locus-tag	class	description
H1R14_RS00425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS00685	COG3550	peptidyl-serine autophosphorylation
H1R14_RS00765	COG1358	cellular component organization or biogenesis
H1R14_RS00795	COG4245	von Willebrand factor, type A
H1R14_RS00800	COG4245	von Willebrand factor, type A
H1R14_RS00945	COG0210	DNA helicase
H1R14_RS01030	COG1192	Involved in chromosome partitioning
H1R14_RS01175	COG2890	protein-(glutamine-N5) methyltransferase activity
H1R14_RS01365	COG3385	transposase activity
H1R14_RS01525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1R14_RS01545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1R14_RS01545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1R14_RS01600	COG1396	sequence-specific DNA binding
H1R14_RS01710	COG0542	response to heat
H1R14_RS01730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H1R14_RS01735	COG4988	ABC transporter
H1R14_RS01740	COG0492	ferredoxin-NADP+ reductase activity
H1R14_RS01745	COG1522	sequence-specific DNA binding
H1R14_RS01750	COG1178	ABC-type Fe3 transport system permease component
H1R14_RS01750	COG1674	ftsk spoiiie
H1R14_RS01760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1R14_RS01770	COG0243	molybdopterin cofactor binding
H1R14_RS01775	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS01780	COG3302	dmso reductase anchor subunit
H1R14_RS01785	COG1335	isochorismatase
H1R14_RS01795	COG0531	amino acid
H1R14_RS01805	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1R14_RS01810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1R14_RS01815	COG4974	Belongs to the 'phage' integrase family
H1R14_RS01890	COG4695	Portal protein
H1R14_RS01985	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H1R14_RS02000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1R14_RS02045	COG1882	Formate acetyltransferase
H1R14_RS02050	COG2116	formate transmembrane transporter activity
H1R14_RS02055	COG1944	ATP diphosphatase activity
H1R14_RS02060	COG2323	membrane
H1R14_RS02075	COG0501	Belongs to the peptidase M48B family
H1R14_RS02085	COG0539	negative regulation of cytoplasmic translation
H1R14_RS02095	COG2333	competence protein COMEC
H1R14_RS02095	COG0658	competence protein
H1R14_RS02100	COG1132	(ABC) transporter
H1R14_RS02105	COG1663	tetraacyldisaccharide 4'-kinase activity
H1R14_RS02110	COG3214	Protein conserved in bacteria
H1R14_RS02125	COG3173	Aminoglycoside phosphotransferase
H1R14_RS02130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H1R14_RS02135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1R14_RS02145	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H1R14_RS02155	COG2989	Protein conserved in bacteria
H1R14_RS02160	COG3108	Peptidase M15
H1R14_RS02165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1R14_RS02170	COG1448	Aminotransferase
H1R14_RS02175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1R14_RS02190	COG0308	aminopeptidase N
H1R14_RS02195	COG1116	anion transmembrane transporter activity
H1R14_RS02200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1R14_RS02210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1R14_RS02215	COG0431	NADPH-dependent FMN reductase
H1R14_RS02220	COG3539	Fimbrial protein
H1R14_RS02225	COG3121	Chaperone
H1R14_RS02230	COG3188	usher protein
H1R14_RS02235	COG3539	Fimbrial protein
H1R14_RS02240	COG3539	Fimbrial protein
H1R14_RS02245	COG3539	Fimbrial protein
H1R14_RS02250	COG3121	Chaperone
H1R14_RS02265	COG3217	Mosc domain protein beta barrel domain protein
H1R14_RS02265	COG0633	Ferredoxin
H1R14_RS02275	COG0488	(ABC) transporter
H1R14_RS02280	COG2995	paraquat-inducible protein a
H1R14_RS02285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1R14_RS02285	COG3008	intermembrane lipid transfer
H1R14_RS02290	COG3009	Protein conserved in bacteria
H1R14_RS02295	COG3130	regulation of translation
H1R14_RS02305	COG1067	ATP-dependent peptidase activity
H1R14_RS02315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1R14_RS02315	COG2885	chlorophyll binding
H1R14_RS02325	COG3070	regulator of competence-specific genes
H1R14_RS02330	COG1289	transmembrane transporter activity
H1R14_RS02335	COG3304	Inner membrane component domain
H1R14_RS02340	COG0210	DNA helicase
H1R14_RS02355	COG1832	CoA-binding protein
H1R14_RS02370	COG1254	Belongs to the acylphosphatase family
H1R14_RS02375	COG2920	part of a sulfur-relay system
H1R14_RS02380	COG0670	Belongs to the BI1 family
H1R14_RS02390	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H1R14_RS02395	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H1R14_RS02400	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
H1R14_RS02405	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H1R14_RS02410	COG1999	signal sequence binding
H1R14_RS02415	COG1773	rubredoxin
H1R14_RS02420	COG1271	oxidase subunit
H1R14_RS02425	COG1294	oxidase, subunit
H1R14_RS02440	COG0489	protein tyrosine kinase activity
H1R14_RS02440	COG3206	protein involved in exopolysaccharide biosynthesis
H1R14_RS02445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1R14_RS02450	COG1596	polysaccharide export
H1R14_RS02455	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1R14_RS02475	COG1278	Cold shock
H1R14_RS02480	COG1278	Cold shock
H1R14_RS02500	COG0348	domain, Protein
H1R14_RS02505	COG2205	protein histidine kinase activity
H1R14_RS02505	COG2198	Histidine kinase
H1R14_RS02505	COG0784	Response regulator, receiver
H1R14_RS02510	COG1879	ABC-type sugar transport system periplasmic component
H1R14_RS02515	COG0745	RESPONSE REGULATOR receiver
H1R14_RS02520	COG3005	denitrification pathway
H1R14_RS02525	COG0243	molybdopterin cofactor binding
H1R14_RS02530	COG3381	protein complex oligomerization
H1R14_RS02565	COG3729	General stress protein
H1R14_RS02570	COG2233	PERMEase
H1R14_RS02605	COG1309	transcriptional regulator
H1R14_RS02610	COG0506	proline dehydrogenase activity
H1R14_RS02610	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1R14_RS02610	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1R14_RS02620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1R14_RS02630	COG2822	iron ion transport
H1R14_RS02640	COG1702	phosphate starvation-inducible protein PhoH
H1R14_RS02645	COG3658	cytochrome
H1R14_RS02650	COG1215	transferase activity, transferring glycosyl groups
H1R14_RS02655	COG0726	polysaccharide deacetylase
H1R14_RS02655	COG1649	PFAM Uncharacterised BCR, COG1649
H1R14_RS02660	COG0457	Tetratricopeptide repeat
H1R14_RS02665	COG3706	GGDEF domain
H1R14_RS02710	COG3381	protein complex oligomerization
H1R14_RS02720	COG1462	curli production assembly transport component CsgG
H1R14_RS02735	COG2197	response regulator
H1R14_RS02760	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H1R14_RS02765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1R14_RS02780	COG2943	transferase activity, transferring hexosyl groups
H1R14_RS02785	COG5645	(Lipo)protein
H1R14_RS02800	COG1560	Kdo2-lipid A biosynthetic process
H1R14_RS02810	COG2353	YceI-like domain
H1R14_RS02815	COG3038	cytochrome b561
H1R14_RS02850	COG2999	glutathione oxidoreductase activity
H1R14_RS02860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1R14_RS02870	COG0673	inositol 2-dehydrogenase activity
H1R14_RS02875	COG0728	peptidoglycan biosynthetic process
H1R14_RS02880	COG3418	PFAM FlgN family protein
H1R14_RS02885	COG2747	anti-sigma28 factor FlgM
H1R14_RS02890	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H1R14_RS02895	COG1815	bacterial-type flagellum-dependent cell motility
H1R14_RS02900	COG1558	bacterial-type flagellum-dependent cell motility
H1R14_RS02905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H1R14_RS02910	COG1749	Flagellar hook protein flgE
H1R14_RS02915	COG4787	bacterial-type flagellum-dependent cell motility
H1R14_RS02920	COG4786	Flagellar basal body rod
H1R14_RS02935	COG1705	Flagellar rod assembly protein muramidase FlgJ
H1R14_RS02935	COG3951	Flagellar rod assembly protein muramidase FlgJ
H1R14_RS02940	COG1256	bacterial-type flagellum assembly
H1R14_RS02945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H1R14_RS02950	COG1530	ribonuclease E activity
H1R14_RS02955	COG0564	pseudouridine synthase activity
H1R14_RS02960	COG0424	maF-like protein
H1R14_RS02965	COG1399	metal-binding, possibly nucleic acid-binding protein
H1R14_RS02985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1R14_RS02990	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS03000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1R14_RS03005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1R14_RS03010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1R14_RS03020	COG0470	DNA polymerase III
H1R14_RS03025	COG0084	hydrolase, TatD family'
H1R14_RS03030	COG1263	PTS System
H1R14_RS03030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS03035	COG4773	Receptor
H1R14_RS03040	COG0537	adenosine 5'-monophosphoramidase activity
H1R14_RS03045	COG5633	Lipoprotein
H1R14_RS03050	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
H1R14_RS03070	COG1252	NADH dehydrogenase
H1R14_RS03075	COG3134	Outer membrane lipoprotein
H1R14_RS03080	COG1309	transcriptional regulator
H1R14_RS03090	COG1376	ErfK ybiS ycfS ynhG family protein
H1R14_RS03090	COG1388	LysM domain
H1R14_RS03095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1R14_RS03100	COG4763	Acyl-transferase
H1R14_RS03105	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1R14_RS03110	COG1136	(ABC) transporter
H1R14_RS03115	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1R14_RS03125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1R14_RS03130	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1R14_RS03140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H1R14_RS03145	COG1177	transmembrane transport
H1R14_RS03155	COG3842	ATPase activity
H1R14_RS03165	COG2850	peptidyl-arginine hydroxylation
H1R14_RS03170	COG2205	protein histidine kinase activity
H1R14_RS03175	COG0745	RESPONSE REGULATOR receiver
H1R14_RS03180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1R14_RS03200	COG1187	pseudouridine synthase activity
H1R14_RS03205	COG0538	isocitrate dehydrogenase activity
H1R14_RS03225	COG5562	phage envelope protein
H1R14_RS03230	COG0789	Transcriptional regulator
H1R14_RS03235	COG2200	EAL domain
H1R14_RS03260	COG2200	EAL domain
H1R14_RS03310	COG2894	cell division
H1R14_RS03335	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1R14_RS03350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1R14_RS03355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1R14_RS03360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H1R14_RS03375	COG2719	SpoVR family
H1R14_RS03385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1R14_RS03395	COG1619	proteins homologs of microcin C7 resistance protein MccF
H1R14_RS03405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H1R14_RS03410	COG2261	transglycosylase associated protein
H1R14_RS03425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS03425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1R14_RS03425	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H1R14_RS03430	COG1461	Dihydroxyacetone kinase
H1R14_RS03435	COG2376	Dihydroxyacetone kinase
H1R14_RS03440	COG3284	Transcriptional regulator
H1R14_RS03445	COG3468	outer membrane autotransporter barrel domain protein
H1R14_RS03450	COG0012	GTP binding
H1R14_RS03465	COG0659	secondary active sulfate transmembrane transporter activity
H1R14_RS03470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1R14_RS03495	COG2890	protein-(glutamine-N5) methyltransferase activity
H1R14_RS03500	COG3094	Invasion gene expression up-regulator, SirB
H1R14_RS03505	COG2912	Transglutaminase-like superfamily
H1R14_RS03530	COG0387	Pfam Sodium calcium exchanger
H1R14_RS03535	COG4572	Cation transport regulator
H1R14_RS03540	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H1R14_RS03545	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1R14_RS03550	COG4932	domain protein
H1R14_RS03555	COG2197	response regulator
H1R14_RS03560	COG3850	Histidine kinase
H1R14_RS03565	COG2223	nitrite transmembrane transporter activity
H1R14_RS03570	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H1R14_RS03575	COG1140	nitrate reductase beta subunit
H1R14_RS03580	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H1R14_RS03585	COG2181	nitrate reductase activity
H1R14_RS03620	COG0788	formyltetrahydrofolate deformylase activity
H1R14_RS03630	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1R14_RS03635	COG0745	RESPONSE REGULATOR receiver
H1R14_RS03640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1R14_RS03650	COG1435	thymidine kinase activity
H1R14_RS03660	COG1454	alcohol dehydrogenase
H1R14_RS03660	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS03665	COG2095	MarC family integral membrane protein
H1R14_RS03675	COG4166	transmembrane transport
H1R14_RS03680	COG0601	transmembrane transport
H1R14_RS03685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1R14_RS03690	COG0444	Belongs to the ABC transporter superfamily
H1R14_RS03695	COG4608	Belongs to the ABC transporter superfamily
H1R14_RS03715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1R14_RS03720	COG2350	Protein conserved in bacteria
H1R14_RS03725	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H1R14_RS03730	COG1607	acyl-coa hydrolase
H1R14_RS03750	COG3047	cAMP biosynthetic process
H1R14_RS03755	COG3685	Protein conserved in bacteria
H1R14_RS03760	COG3685	Protein conserved in bacteria
H1R14_RS03765	COG3729	General stress protein
H1R14_RS03780	COG0135	phosphoribosylanthranilate isomerase activity
H1R14_RS03780	COG0134	indole-3-glycerol-phosphate synthase activity
H1R14_RS03785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1R14_RS03785	COG0512	Glutamine amidotransferase of anthranilate synthase
H1R14_RS03790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1R14_RS03800	COG0613	PHP domain protein
H1R14_RS03805	COG0009	L-threonylcarbamoyladenylate synthase
H1R14_RS03810	COG4907	membrane protein (DUF2207)
H1R14_RS03815	COG1187	pseudouridine synthase activity
H1R14_RS03820	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H1R14_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS03830	COG0616	signal peptide processing
H1R14_RS03840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1R14_RS03845	COG0583	DNA-binding transcription factor activity
H1R14_RS03865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1R14_RS03875	COG0671	phosphoesterase, PA-phosphatase related
H1R14_RS03880	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H1R14_RS03885	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H1R14_RS03895	COG0023	Translation Initiation Factor
H1R14_RS03905	COG1349	DNA-binding transcription factor activity
H1R14_RS03915	COG5001	Diguanylate cyclase
H1R14_RS03930	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1R14_RS03930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1R14_RS03935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H1R14_RS03940	COG2852	Protein conserved in bacteria
H1R14_RS03945	COG4172	Belongs to the ABC transporter superfamily
H1R14_RS03950	COG4172	Belongs to the ABC transporter superfamily
H1R14_RS03955	COG4171	peptide transport system, permease
H1R14_RS03960	COG4168	peptide transport system, permease
H1R14_RS03965	COG4166	transmembrane transport
H1R14_RS03975	COG0531	amino acid
H1R14_RS03985	COG0174	glutamine synthetase
H1R14_RS03990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H1R14_RS03995	COG1917	Cupin 2, conserved barrel domain protein
H1R14_RS03995	COG1396	sequence-specific DNA binding
H1R14_RS04000	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS04005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1R14_RS04010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1R14_RS04015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H1R14_RS04020	COG1842	Phage shock protein A
H1R14_RS04030	COG1983	PspC domain protein
H1R14_RS04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1R14_RS04045	COG0366	Alpha amylase catalytic
H1R14_RS04050	COG1653	transport
H1R14_RS04055	COG1175	transmembrane transport
H1R14_RS04060	COG0395	ABC-type sugar transport system, permease component
H1R14_RS04065	COG1063	alcohol dehydrogenase
H1R14_RS04070	COG1082	Xylose isomerase domain protein TIM barrel
H1R14_RS04075	COG0673	inositol 2-dehydrogenase activity
H1R14_RS04085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1R14_RS04090	COG3842	ATPase activity
H1R14_RS04100	COG1609	Transcriptional regulator
H1R14_RS04105	COG3106	COG3106 Predicted ATPase
H1R14_RS04115	COG3283	Transcriptional regulator of aromatic amino acids metabolism
H1R14_RS04120	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H1R14_RS04125	COG4948	Mandelate Racemase Muconate Lactonizing
H1R14_RS04130	COG2866	Carboxypeptidase
H1R14_RS04145	COG1073	alpha beta
H1R14_RS04150	COG0583	DNA-binding transcription factor activity
H1R14_RS04155	COG4166	transmembrane transport
H1R14_RS04160	COG0668	transmembrane transport
H1R14_RS04165	COG3182	Iron-regulated membrane protein
H1R14_RS04170	COG0589	response to stress
H1R14_RS04175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1R14_RS04180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1R14_RS04185	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H1R14_RS04190	COG1473	amidohydrolase
H1R14_RS04195	COG1473	amidohydrolase
H1R14_RS04200	COG0583	DNA-binding transcription factor activity
H1R14_RS04205	COG2840	Smr protein MutS2
H1R14_RS04210	COG3706	GGDEF domain
H1R14_RS04220	COG0513	Belongs to the DEAD box helicase family
H1R14_RS04230	COG0589	response to stress
H1R14_RS04235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1R14_RS04240	COG0674	pyruvate-flavodoxin oxidoreductase activity
H1R14_RS04240	COG1013	pyruvate-flavodoxin oxidoreductase activity
H1R14_RS04240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H1R14_RS04240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1R14_RS04245	COG3042	response to heat
H1R14_RS04250	COG3187	Heat shock protein
H1R14_RS04255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1R14_RS04260	COG2911	Protein conserved in bacteria
H1R14_RS04270	COG3784	Protein of unknown function (DUF1318)
H1R14_RS04275	COG2207	Transcriptional regulator
H1R14_RS04280	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS04285	COG3733	amine oxidase
H1R14_RS04290	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS04290	COG2030	dehydratase
H1R14_RS04295	COG3396	Phenylacetate-CoA oxygenase
H1R14_RS04300	COG3460	Phenylacetate-CoA oxygenase
H1R14_RS04305	COG3396	Phenylacetate-CoA oxygenase
H1R14_RS04310	COG2151	metal-sulfur cluster biosynthetic enzyme
H1R14_RS04315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1R14_RS04320	COG1024	Enoyl-CoA hydratase
H1R14_RS04325	COG1024	Enoyl-CoA hydratase
H1R14_RS04330	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1R14_RS04335	COG2050	protein possibly involved in aromatic compounds catabolism
H1R14_RS04340	COG0183	Belongs to the thiolase family
H1R14_RS04345	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1R14_RS04350	COG3327	negative regulation of DNA-templated transcription, initiation
H1R14_RS04355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1R14_RS04370	COG0667	Aldo Keto reductase
H1R14_RS04380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1R14_RS04385	COG4589	Belongs to the CDS family
H1R14_RS04390	COG2267	carboxylic ester hydrolase activity
H1R14_RS04395	COG2453	phosphatase
H1R14_RS04395	COG0671	phosphoesterase, PA-phosphatase related
H1R14_RS04405	COG1643	Atp-dependent helicase
H1R14_RS04410	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H1R14_RS04415	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS04425	COG3038	cytochrome b561
H1R14_RS04440	COG0840	transmembrane signaling receptor activity
H1R14_RS04445	COG0583	DNA-binding transcription factor activity
H1R14_RS04450	COG5383	Protein conserved in bacteria
H1R14_RS04460	COG2841	Protein conserved in bacteria
H1R14_RS04465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1R14_RS04470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1R14_RS04475	COG1275	C4-dicarboxylate transporter malic acid transport protein
H1R14_RS04480	COG0500	methyltransferase
H1R14_RS04495	COG0675	Transposase, IS605 OrfB family
H1R14_RS04500	COG3135	benzoate transporter
H1R14_RS04505	COG1396	sequence-specific DNA binding
H1R14_RS04510	COG0826	peptidase U32
H1R14_RS04520	COG1724	mRNA binding
H1R14_RS04525	COG1598	PFAM Uncharacterised protein family UPF0150
H1R14_RS04530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1R14_RS04535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H1R14_RS04540	COG3842	ATPase activity
H1R14_RS04545	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1R14_RS04550	COG1177	transmembrane transport
H1R14_RS04575	COG3238	Protein conserved in bacteria
H1R14_RS04580	COG1247	-acetyltransferase
H1R14_RS04585	COG2130	NADP-dependent
H1R14_RS04590	COG1802	Transcriptional regulator
H1R14_RS04595	COG4772	TonB-dependent receptor
H1R14_RS04600	COG3391	amine dehydrogenase activity
H1R14_RS04605	COG1113	amino acid transport
H1R14_RS04610	COG0625	glutathione transferase activity
H1R14_RS04620	COG3501	Rhs element vgr protein
H1R14_RS04640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1R14_RS04645	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H1R14_RS04650	COG0384	phenazine biosynthesis protein PhzF
H1R14_RS04655	COG2181	nitrate reductase activity
H1R14_RS04660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H1R14_RS04665	COG1140	nitrate reductase beta subunit
H1R14_RS04670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H1R14_RS04675	COG2223	nitrite transmembrane transporter activity
H1R14_RS04685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1R14_RS04690	COG0697	spore germination
H1R14_RS04700	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS04705	COG2864	formate dehydrogenase
H1R14_RS04710	COG3093	addiction module antidote protein HigA
H1R14_RS04715	COG1064	alcohol dehydrogenase
H1R14_RS04735	COG1764	response to oxidative stress
H1R14_RS04740	COG4608	Belongs to the ABC transporter superfamily
H1R14_RS04745	COG0444	Belongs to the ABC transporter superfamily
H1R14_RS04750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1R14_RS04755	COG0601	transmembrane transport
H1R14_RS04760	COG0747	negative chemotaxis
H1R14_RS04765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H1R14_RS04770	COG2200	EAL domain
H1R14_RS04770	COG2199	diguanylate cyclase activity
H1R14_RS04770	COG2202	Pas domain
H1R14_RS04775	COG3706	GGDEF domain
H1R14_RS04790	COG0531	amino acid
H1R14_RS04795	COG0076	glutamate decarboxylase activity
H1R14_RS04800	COG0612	Peptidase, M16
H1R14_RS04810	COG4178	(ABC) transporter
H1R14_RS04820	COG0641	radical SAM
H1R14_RS04825	COG3119	arylsulfatase activity
H1R14_RS04830	COG2207	Transcriptional regulator
H1R14_RS04840	COG0243	molybdopterin cofactor binding
H1R14_RS04845	COG3539	Fimbrial protein
H1R14_RS04850	COG3539	Fimbrial protein
H1R14_RS04855	COG3539	Fimbrial protein
H1R14_RS04870	COG2801	Transposase and inactivated derivatives
H1R14_RS04880	COG3550	peptidyl-serine autophosphorylation
H1R14_RS04885	COG1396	sequence-specific DNA binding
H1R14_RS04945	COG3781	membrane
H1R14_RS04965	COG2066	Belongs to the glutaminase family
H1R14_RS04970	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS04975	COG0583	DNA-binding transcription factor activity
H1R14_RS05005	COG1846	Transcriptional regulator
H1R14_RS05010	COG4977	sequence-specific DNA binding
H1R14_RS05020	COG0697	spore germination
H1R14_RS05025	COG2814	Major facilitator Superfamily
H1R14_RS05035	COG3706	GGDEF domain
H1R14_RS05040	COG3111	PFAM Bacterial OB fold (BOF) protein
H1R14_RS05045	COG1546	Belongs to the CinA family
H1R14_RS05050	COG0339	signal peptide processing
H1R14_RS05055	COG4221	oxidoreductase activity
H1R14_RS05060	COG1802	Transcriptional regulator
H1R14_RS05070	COG0246	Mannitol dehydrogenase
H1R14_RS05100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1R14_RS05105	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H1R14_RS05110	COG5301	cellulose 1,4-beta-cellobiosidase activity
H1R14_RS05130	COG5562	phage envelope protein
H1R14_RS05155	COG1278	Cold shock
H1R14_RS05165	COG3772	lysozyme
H1R14_RS05180	COG1278	Cold shock
H1R14_RS05185	COG1278	Cold shock
H1R14_RS05195	COG0484	heat shock protein binding
H1R14_RS05200	COG1403	HNH endonuclease
H1R14_RS05220	COG2026	Addiction module toxin, RelE StbE family
H1R14_RS05225	COG3077	Addiction module antitoxin, RelB DinJ family
H1R14_RS05240	COG2801	Transposase and inactivated derivatives
H1R14_RS05255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1R14_RS05265	COG0582	viral genome integration into host DNA
H1R14_RS05275	COG1063	alcohol dehydrogenase
H1R14_RS05280	COG4948	Mandelate Racemase Muconate Lactonizing
H1R14_RS05295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1R14_RS05310	COG0243	molybdopterin cofactor binding
H1R14_RS05315	COG0243	molybdopterin cofactor binding
H1R14_RS05320	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS05325	COG3302	dmso reductase anchor subunit
H1R14_RS05330	COG3381	protein complex oligomerization
H1R14_RS05340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H1R14_RS05345	COG1940	carbohydrate kinase activity
H1R14_RS05350	COG0583	DNA-binding transcription factor activity
H1R14_RS05355	COG2814	Major facilitator Superfamily
H1R14_RS05370	COG3591	Belongs to the peptidase S1B family
H1R14_RS05385	COG0628	permease
H1R14_RS05390	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H1R14_RS05395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H1R14_RS05405	COG0531	amino acid
H1R14_RS05415	COG3136	membrane protein required for alginate biosynthesis
H1R14_RS05420	COG0745	RESPONSE REGULATOR receiver
H1R14_RS05425	COG2205	protein histidine kinase activity
H1R14_RS05435	COG0114	fumarate hydratase activity
H1R14_RS05440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1R14_RS05440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1R14_RS05445	COG1482	cell wall glycoprotein biosynthetic process
H1R14_RS05450	COG5339	Protein conserved in bacteria
H1R14_RS05465	COG3250	beta-galactosidase activity
H1R14_RS05470	COG1309	transcriptional regulator
H1R14_RS05475	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS05480	COG1609	Transcriptional regulator
H1R14_RS05485	COG1263	PTS System
H1R14_RS05485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS05490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H1R14_RS05500	COG0673	inositol 2-dehydrogenase activity
H1R14_RS05540	COG4659	FMN binding
H1R14_RS05550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1R14_RS05555	COG3104	oligopeptide transport
H1R14_RS05560	COG0625	glutathione transferase activity
H1R14_RS05565	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H1R14_RS05580	COG3895	Periplasmic Protein
H1R14_RS05590	COG3133	Outer membrane lipoprotein
H1R14_RS05605	COG1566	PFAM secretion protein HlyD family protein
H1R14_RS05610	COG1289	transmembrane transporter activity
H1R14_RS05615	COG2032	superoxide dismutase activity
H1R14_RS05620	COG4989	oxidoreductase activity
H1R14_RS05625	COG3313	Fe-S protein
H1R14_RS05630	COG1309	transcriptional regulator
H1R14_RS05635	COG1902	pentaerythritol trinitrate reductase activity
H1R14_RS05640	COG0346	lactoylglutathione lyase activity
H1R14_RS05645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1R14_RS05650	COG1201	RNA secondary structure unwinding
H1R14_RS05655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1R14_RS05660	COG0791	NLP P60 protein
H1R14_RS05665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1R14_RS05670	COG2814	Major facilitator Superfamily
H1R14_RS05685	COG0583	DNA-binding transcription factor activity
H1R14_RS05690	COG2814	Major facilitator Superfamily
H1R14_RS05695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1R14_RS05700	COG0307	riboflavin synthase, alpha
H1R14_RS05710	COG3468	outer membrane autotransporter barrel domain protein
H1R14_RS05730	COG4529	Protein conserved in bacteria
H1R14_RS05740	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
H1R14_RS05745	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS05755	COG2414	aldehyde ferredoxin oxidoreductase
H1R14_RS05760	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS05770	COG0469	pyruvate kinase activity
H1R14_RS05775	COG4238	major outer membrane lipoprotein
H1R14_RS05780	COG1376	ErfK ybiS ycfS ynhG family protein
H1R14_RS05795	COG0719	Fe-S assembly protein
H1R14_RS05800	COG0396	ATPase activity
H1R14_RS05805	COG0719	Fe-S assembly protein
H1R14_RS05810	COG0316	Belongs to the HesB IscA family
H1R14_RS05820	COG2050	protein possibly involved in aromatic compounds catabolism
H1R14_RS05825	COG0277	FAD linked oxidase domain protein
H1R14_RS05825	COG0247	lactate metabolic process
H1R14_RS05830	COG0628	permease
H1R14_RS05850	COG2271	Major facilitator Superfamily
H1R14_RS05865	COG4670	ketone body catabolic process
H1R14_RS05870	COG1960	acyl-CoA dehydrogenase activity
H1R14_RS05875	COG2207	Transcriptional regulator
H1R14_RS05875	COG1917	Cupin 2, conserved barrel domain protein
H1R14_RS05880	COG2086	electron transfer activity
H1R14_RS05885	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H1R14_RS05890	COG0644	oxidoreductase
H1R14_RS05895	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1R14_RS05900	COG0318	PFAM AMP-dependent synthetase and ligase
H1R14_RS05905	COG0574	Belongs to the PEP-utilizing enzyme family
H1R14_RS05905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1R14_RS05915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1R14_RS05920	COG4256	Hemin uptake protein
H1R14_RS05930	COG2200	EAL domain
H1R14_RS05935	COG0791	NLP P60 protein
H1R14_RS05945	COG0386	Belongs to the glutathione peroxidase family
H1R14_RS05965	COG4974	Belongs to the 'phage' integrase family
H1R14_RS06025	COG0072	phenylalanine-tRNA ligase activity
H1R14_RS06025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1R14_RS06070	COG3137	Salt-induced outer membrane protein
H1R14_RS06075	COG1105	Belongs to the carbohydrate kinase PfkB family
H1R14_RS06085	COG3001	Fructosamine kinase
H1R14_RS06095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1R14_RS06100	COG1988	membrane-bound metal-dependent
H1R14_RS06120	COG0753	catalase activity
H1R14_RS06130	COG1486	melibiose metabolic process
H1R14_RS06135	COG2169	Transcriptional regulator
H1R14_RS06135	COG1917	Cupin 2, conserved barrel domain protein
H1R14_RS06140	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1R14_RS06145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R14_RS06150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R14_RS06155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1R14_RS06165	COG0322	excinuclease ABC activity
H1R14_RS06175	COG3678	ATP-independent chaperone mediated protein folding
H1R14_RS06205	COG0708	Exodeoxyribonuclease III
H1R14_RS06210	COG0398	Pfam SNARE associated Golgi protein
H1R14_RS06220	COG0398	Pfam SNARE associated Golgi protein
H1R14_RS06225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1R14_RS06230	COG4134	Bacterial extracellular solute-binding protein
H1R14_RS06235	COG4135	transport system, permease component
H1R14_RS06240	COG4136	ATPase activity
H1R14_RS06245	COG2897	thiosulfate sulfurtransferase activity
H1R14_RS06250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1R14_RS06255	COG0494	nUDIX hydrolase
H1R14_RS06265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1R14_RS06275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1R14_RS06285	COG0778	Nitroreductase
H1R14_RS06290	COG0616	signal peptide processing
H1R14_RS06295	COG0252	asparaginase activity
H1R14_RS06300	COG1335	isochorismatase
H1R14_RS06305	COG2814	Major facilitator Superfamily
H1R14_RS06310	COG1349	DNA-binding transcription factor activity
H1R14_RS06315	COG0667	Aldo Keto reductase
H1R14_RS06320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS06325	COG0191	fructose-bisphosphate aldolase activity
H1R14_RS06330	COG1063	alcohol dehydrogenase
H1R14_RS06335	COG2271	Major facilitator Superfamily
H1R14_RS06340	COG1063	alcohol dehydrogenase
H1R14_RS06345	COG3139	Protein of unknown function (DUF1315)
H1R14_RS06355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1R14_RS06360	COG0676	glucose-6-phosphate 1-epimerase activity
H1R14_RS06365	COG0656	L-ascorbic acid biosynthetic process
H1R14_RS06370	COG3713	MltA-interacting MipA family protein
H1R14_RS06375	COG2766	serine protein kinase
H1R14_RS06385	COG2199	diguanylate cyclase activity
H1R14_RS06390	COG2199	diguanylate cyclase activity
H1R14_RS06395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1R14_RS06410	COG2207	Transcriptional regulator
H1R14_RS06415	COG2807	transmembrane transport
H1R14_RS06420	COG3189	MarR family transcriptional regulator
H1R14_RS06425	COG3042	response to heat
H1R14_RS06430	COG2199	diguanylate cyclase activity
H1R14_RS06430	COG2203	Gaf domain
H1R14_RS06445	COG2261	transglycosylase associated protein
H1R14_RS06460	COG3385	transposase activity
H1R14_RS06465	COG3615	Tellurite resistance protein tehB
H1R14_RS06475	COG0583	DNA-binding transcription factor activity
H1R14_RS06480	COG0473	3-isopropylmalate dehydrogenase activity
H1R14_RS06490	COG4638	Rieske (2fe-2S)
H1R14_RS06500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H1R14_RS06505	COG0318	PFAM AMP-dependent synthetase and ligase
H1R14_RS06510	COG3065	identical protein binding
H1R14_RS06515	COG1214	PFAM Peptidase M22, glycoprotease
H1R14_RS06520	COG1199	ATP-dependent helicase activity
H1R14_RS06525	COG0251	oxidation-reduction process
H1R14_RS06540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1R14_RS06550	COG1760	l-serine dehydratase
H1R14_RS06555	COG2200	EAL domain
H1R14_RS06560	COG1253	flavin adenine dinucleotide binding
H1R14_RS06565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS06565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS06570	COG3715	PTS system
H1R14_RS06575	COG3716	PTS system mannose fructose sorbose family IID component
H1R14_RS06590	COG2226	methyltransferase
H1R14_RS06620	COG1414	Transcriptional regulator
H1R14_RS06625	COG2814	Major facilitator Superfamily
H1R14_RS06635	COG0793	Belongs to the peptidase S41A family
H1R14_RS06645	COG1956	GAF domain-containing protein
H1R14_RS06650	COG2995	paraquat-inducible protein a
H1R14_RS06655	COG3008	intermembrane lipid transfer
H1R14_RS06675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1R14_RS06685	COG1276	copper resistance
H1R14_RS06690	COG2372	response to copper ion
H1R14_RS06700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1R14_RS06705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1R14_RS06710	COG1770	oligopeptidase
H1R14_RS06715	COG2979	Protein of unknown function (DUF533)
H1R14_RS06725	COG3141	response to X-ray
H1R14_RS06735	COG0800	Aldolase
H1R14_RS06740	COG0129	dihydroxy-acid dehydratase activity
H1R14_RS06745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H1R14_RS06750	COG1737	Transcriptional regulator
H1R14_RS06755	COG0469	pyruvate kinase activity
H1R14_RS06760	COG1560	Kdo2-lipid A biosynthetic process
H1R14_RS06765	COG0739	heme binding
H1R14_RS06770	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H1R14_RS06780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1R14_RS06810	COG0217	transcriptional regulatory protein
H1R14_RS06815	COG0494	nUDIX hydrolase
H1R14_RS06825	COG1335	isochorismatase
H1R14_RS06830	COG1801	Protein of unknown function DUF72
H1R14_RS06835	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H1R14_RS06850	COG0243	molybdopterin cofactor binding
H1R14_RS06855	COG3005	denitrification pathway
H1R14_RS06865	COG3102	Protein conserved in bacteria
H1R14_RS06875	COG3755	Protein conserved in bacteria
H1R14_RS06885	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1R14_RS06890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1R14_RS06895	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H1R14_RS06900	COG0745	RESPONSE REGULATOR receiver
H1R14_RS06905	COG2201	protein-glutamate methylesterase activity
H1R14_RS06910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H1R14_RS06915	COG0840	transmembrane signaling receptor activity
H1R14_RS06920	COG0840	transmembrane signaling receptor activity
H1R14_RS06925	COG0835	chemotaxis
H1R14_RS06930	COG0643	Histidine kinase
H1R14_RS06930	COG2198	Histidine kinase
H1R14_RS06935	COG1360	Flagellar Motor Protein
H1R14_RS06940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H1R14_RS06955	COG0589	response to stress
H1R14_RS06965	COG1877	trehalose-phosphatase activity
H1R14_RS06970	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS06975	COG1129	ABC transporter
H1R14_RS06980	COG1879	ABC-type sugar transport system periplasmic component
H1R14_RS06985	COG1528	Iron-storage protein
H1R14_RS07005	COG1528	Iron-storage protein
H1R14_RS07015	COG0814	amino acid
H1R14_RS07020	COG3012	SEC-C Motif Domain Protein
H1R14_RS07020	COG3318	Belongs to the UPF0149 family
H1R14_RS07030	COG3344	reverse transcriptase
H1R14_RS07125	COG2197	response regulator
H1R14_RS07140	COG2197	response regulator
H1R14_RS07170	COG1191	sigma factor activity
H1R14_RS07180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H1R14_RS07185	COG1516	flagellar protein fliS
H1R14_RS07195	COG0366	Alpha amylase catalytic
H1R14_RS07205	COG2391	methyltransferase activity
H1R14_RS07210	COG0425	Belongs to the sulfur carrier protein TusA family
H1R14_RS07215	COG2135	peptidase activity
H1R14_RS07220	COG0675	Transposase, IS605 OrfB family
H1R14_RS07230	COG2207	Transcriptional regulator
H1R14_RS07235	COG1881	PFAM PEBP family protein
H1R14_RS07240	COG2076	Multidrug Resistance protein
H1R14_RS07250	COG1766	The M ring may be actively involved in energy transduction
H1R14_RS07255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1R14_RS07260	COG1317	bacterial-type flagellum organization
H1R14_RS07265	COG1157	protein secretion by the type III secretion system
H1R14_RS07270	COG2882	bacterial-type flagellum organization
H1R14_RS07275	COG3144	bacterial-type flagellum assembly
H1R14_RS07280	COG1580	Controls the rotational direction of flagella during chemotaxis
H1R14_RS07285	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1R14_RS07290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1R14_RS07295	COG3190	flagellar
H1R14_RS07300	COG1338	Plays a role in the flagellum-specific transport system
H1R14_RS07305	COG1987	bacterial-type flagellum assembly
H1R14_RS07310	COG1684	flagellar biosynthetic protein fliR
H1R14_RS07315	COG2197	response regulator
H1R14_RS07340	COG5475	Uncharacterized small protein (DUF2158)
H1R14_RS07345	COG2354	Protein conserved in bacteria
H1R14_RS07350	COG0697	spore germination
H1R14_RS07355	COG3727	T/G mismatch-specific endonuclease activity
H1R14_RS07360	COG0270	DNA (cytosine-5-)-methyltransferase activity
H1R14_RS07380	COG2205	protein histidine kinase activity
H1R14_RS07385	COG0745	RESPONSE REGULATOR receiver
H1R14_RS07390	COG2351	hydroxyisourate hydrolase activity
H1R14_RS07405	COG3443	Belongs to the bacterial solute-binding protein 9 family
H1R14_RS07410	COG3038	cytochrome b561
H1R14_RS07440	COG0477	Major facilitator Superfamily
H1R14_RS07445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1R14_RS07450	COG0217	transcriptional regulatory protein
H1R14_RS07480	COG0583	DNA-binding transcription factor activity
H1R14_RS07485	COG0583	DNA-binding transcription factor activity
H1R14_RS07495	COG1376	ErfK ybiS ycfS ynhG family protein
H1R14_RS07510	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
H1R14_RS07530	COG1349	DNA-binding transcription factor activity
H1R14_RS07535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS07550	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H1R14_RS07625	COG1289	transmembrane transporter activity
H1R14_RS07635	COG1686	Belongs to the peptidase S11 family
H1R14_RS07640	COG2925	Exonuclease
H1R14_RS07645	COG0425	Belongs to the sulfur carrier protein TusA family
H1R14_RS07650	COG2391	methyltransferase activity
H1R14_RS07655	COG0531	amino acid
H1R14_RS07665	COG0583	DNA-binding transcription factor activity
H1R14_RS07670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1R14_RS07685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1R14_RS07695	COG0131	Imidazoleglycerol-phosphate dehydratase
H1R14_RS07695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H1R14_RS07700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1R14_RS07725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H1R14_RS07730	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H1R14_RS07735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1R14_RS07770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1R14_RS07775	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H1R14_RS07775	COG0662	Cupin 2, conserved barrel domain protein
H1R14_RS07780	COG1051	belongs to the nudix hydrolase family
H1R14_RS07785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1R14_RS07790	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H1R14_RS07795	COG0297	glycogen (starch) synthase activity
H1R14_RS07795	COG0438	transferase activity, transferring glycosyl groups
H1R14_RS07800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1R14_RS07805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1R14_RS07820	COG0438	transferase activity, transferring glycosyl groups
H1R14_RS07825	COG2327	Polysaccharide pyruvyl transferase
H1R14_RS07830	COG2244	polysaccharide biosynthetic process
H1R14_RS07835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1R14_RS07840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1R14_RS07845	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H1R14_RS07845	COG0662	Cupin 2, conserved barrel domain protein
H1R14_RS07850	COG0297	glycogen (starch) synthase activity
H1R14_RS07855	COG1051	belongs to the nudix hydrolase family
H1R14_RS07860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1R14_RS07865	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H1R14_RS07870	COG0110	maltose O-acetyltransferase activity
H1R14_RS07875	COG1216	Glycosyl transferase, family 2
H1R14_RS07885	COG0438	transferase activity, transferring glycosyl groups
H1R14_RS07890	COG1045	serine acetyltransferase
H1R14_RS07895	COG0463	Glycosyl transferase, family 2
H1R14_RS07900	COG3206	protein involved in exopolysaccharide biosynthesis
H1R14_RS07900	COG0489	protein tyrosine kinase activity
H1R14_RS07905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1R14_RS07910	COG1596	polysaccharide export
H1R14_RS07920	COG1253	flavin adenine dinucleotide binding
H1R14_RS07925	COG2982	Protein involved in outer membrane biogenesis
H1R14_RS07935	COG0572	uridine kinase
H1R14_RS07940	COG5002	protein histidine kinase activity
H1R14_RS07940	COG5001	Diguanylate cyclase
H1R14_RS07940	COG3447	MASE1 domain protein
H1R14_RS07945	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H1R14_RS07950	COG0443	Heat shock 70 kDa protein
H1R14_RS07955	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
H1R14_RS07960	COG0631	protein serine/threonine phosphatase activity
H1R14_RS07965	COG4245	von Willebrand factor, type A
H1R14_RS08000	COG2205	protein histidine kinase activity
H1R14_RS08005	COG0745	RESPONSE REGULATOR receiver
H1R14_RS08040	COG1063	alcohol dehydrogenase
H1R14_RS08045	COG3775	system Galactitol-specific IIC component
H1R14_RS08050	COG3414	Phosphotransferase system galactitol-specific IIB component
H1R14_RS08055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS08070	COG1830	Aldolase
H1R14_RS08075	COG2211	Major facilitator Superfamily
H1R14_RS08080	COG1397	ADP-ribosylglycohydrolase
H1R14_RS08085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS08090	COG2188	Transcriptional regulator
H1R14_RS08095	COG3757	hydrolase, family 25
H1R14_RS08100	COG0351	phosphomethylpyrimidine kinase
H1R14_RS08120	COG5455	response to cobalt ion
H1R14_RS08125	COG3539	Fimbrial protein
H1R14_RS08130	COG3188	usher protein
H1R14_RS08135	COG3121	Chaperone
H1R14_RS08140	COG3539	Fimbrial protein
H1R14_RS08150	COG0489	protein tyrosine kinase activity
H1R14_RS08160	COG3831	ATPase activity
H1R14_RS08165	COG3831	ATPase activity
H1R14_RS08175	COG0714	Associated with various cellular activities
H1R14_RS08180	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H1R14_RS08185	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H1R14_RS08190	COG4715	Zinc finger, swim domain protein
H1R14_RS08195	COG4808	Protein conserved in bacteria
H1R14_RS08200	COG4807	Protein conserved in bacteria
H1R14_RS08205	COG3279	Response regulator of the LytR AlgR family
H1R14_RS08210	COG3275	phosphorelay sensor kinase activity
H1R14_RS08215	COG0789	Transcriptional regulator
H1R14_RS08225	COG1174	glycine betaine transport
H1R14_RS08230	COG1125	glycine betaine transport
H1R14_RS08235	COG1174	glycine betaine transport
H1R14_RS08240	COG1732	Glycine betaine
H1R14_RS08245	COG1472	Belongs to the glycosyl hydrolase 3 family
H1R14_RS08250	COG0277	FAD linked oxidase domain protein
H1R14_RS08255	COG1686	Belongs to the peptidase S11 family
H1R14_RS08265	COG0586	Pfam SNARE associated Golgi protein
H1R14_RS08270	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS08285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1R14_RS08295	COG1346	cytolysis
H1R14_RS08305	COG2949	membrane
H1R14_RS08315	COG0493	'glutamate synthase
H1R14_RS08320	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1R14_RS08320	COG0167	dihydroorotate dehydrogenase activity
H1R14_RS08325	COG4211	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS08330	COG1129	ABC transporter
H1R14_RS08335	COG1879	ABC-type sugar transport system periplasmic component
H1R14_RS08340	COG1609	Transcriptional regulator
H1R14_RS08345	COG2311	Membrane
H1R14_RS08360	COG4771	TonB-dependent receptor
H1R14_RS08365	COG0833	amino acid
H1R14_RS08370	COG0583	DNA-binding transcription factor activity
H1R14_RS08375	COG2855	membrane
H1R14_RS08385	COG1522	sequence-specific DNA binding
H1R14_RS08385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS08390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1R14_RS08400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1R14_RS08405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1R14_RS08415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS08420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS08420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1R14_RS08420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS08425	COG1105	Belongs to the carbohydrate kinase PfkB family
H1R14_RS08430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS08430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS08435	COG2814	Major facilitator Superfamily
H1R14_RS08450	COG0246	Mannitol dehydrogenase
H1R14_RS08455	COG0523	cobalamin synthesis protein
H1R14_RS08460	COG0671	phosphoesterase, PA-phosphatase related
H1R14_RS08465	COG0791	NLP P60 protein
H1R14_RS08470	COG2200	EAL domain
H1R14_RS08475	COG4166	transmembrane transport
H1R14_RS08480	COG4174	ABC transporter (Permease)
H1R14_RS08485	COG4239	(ABC) transporter, permease
H1R14_RS08490	COG4172	Belongs to the ABC transporter superfamily
H1R14_RS08500	COG2814	Major facilitator Superfamily
H1R14_RS08505	COG1187	pseudouridine synthase activity
H1R14_RS08510	COG1061	Type III restriction enzyme res subunit
H1R14_RS08530	COG3083	sulfuric ester hydrolase activity
H1R14_RS08540	COG3468	outer membrane autotransporter barrel domain protein
H1R14_RS08545	COG2197	response regulator
H1R14_RS08550	COG4235	cytochrome complex assembly
H1R14_RS08550	COG3088	subunit of a heme lyase
H1R14_RS08555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1R14_RS08560	COG1138	Cytochrome C-type biogenesis protein
H1R14_RS08570	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1R14_RS08575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1R14_RS08580	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1R14_RS08585	COG4133	protoheme IX ABC transporter activity
H1R14_RS08590	COG3005	denitrification pathway
H1R14_RS08595	COG3043	anaerobic respiration
H1R14_RS08600	COG0348	domain, Protein
H1R14_RS08605	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS08615	COG3062	negative regulation of establishment of protein localization
H1R14_RS08620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS08620	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS08640	COG4615	Cyclic peptide transporter
H1R14_RS08645	COG3145	DNA-N1-methyladenine dioxygenase activity
H1R14_RS08650	COG2169	Transcriptional regulator
H1R14_RS08650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1R14_RS08655	COG1477	protein flavinylation
H1R14_RS08660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1R14_RS08665	COG2198	Histidine kinase
H1R14_RS08665	COG0642	Histidine kinase
H1R14_RS08670	COG2197	response regulator
H1R14_RS08675	COG2205	protein histidine kinase activity
H1R14_RS08675	COG0784	Response regulator, receiver
H1R14_RS08680	COG3852	Histidine kinase
H1R14_RS08685	COG2204	response regulator
H1R14_RS08690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1R14_RS08695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1R14_RS08700	COG2031	fatty acid transporter
H1R14_RS08705	COG0183	Belongs to the thiolase family
H1R14_RS08710	COG4676	Protein conserved in bacteria
H1R14_RS08715	COG5445	Predicted secreted protein (DUF2300)
H1R14_RS08720	COG2373	Large extracellular alpha-helical protein
H1R14_RS08725	COG3234	Protein of unknown function (DUF1175)
H1R14_RS08730	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
H1R14_RS08735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H1R14_RS08745	COG3468	outer membrane autotransporter barrel domain protein
H1R14_RS08750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1R14_RS08755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1R14_RS08760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1R14_RS08765	COG3642	lipopolysaccharide core region biosynthetic process
H1R14_RS08770	COG2814	Major facilitator Superfamily
H1R14_RS08775	COG0583	DNA-binding transcription factor activity
H1R14_RS08780	COG0584	glycerophosphoryl diester phosphodiesterase
H1R14_RS08785	COG2271	Major facilitator Superfamily
H1R14_RS08790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H1R14_RS08800	COG0247	lactate metabolic process
H1R14_RS08820	COG2271	Major facilitator Superfamily
H1R14_RS08825	COG0675	Transposase, IS605 OrfB family
H1R14_RS08895	COG0318	PFAM AMP-dependent synthetase and ligase
H1R14_RS08905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H1R14_RS08920	COG1169	isochorismate synthase
H1R14_RS08925	COG4575	ribosome binding
H1R14_RS08930	COG2153	protein acetylation
H1R14_RS08945	COG2304	oxidoreductase activity
H1R14_RS08950	COG2234	aminopeptidase activity
H1R14_RS08970	COG0457	Tetratricopeptide repeat
H1R14_RS08980	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1R14_RS08985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1R14_RS08995	COG0839	Belongs to the complex I subunit 6 family
H1R14_RS09010	COG1034	ATP synthesis coupled electron transport
H1R14_RS09015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1R14_RS09020	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H1R14_RS09040	COG0583	DNA-binding transcription factor activity
H1R14_RS09045	COG0436	Aminotransferase
H1R14_RS09055	COG0471	metal ion transport
H1R14_RS09055	COG0490	domain, Protein
H1R14_RS09060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1R14_RS09075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1R14_RS09080	COG0280	phosphate acetyltransferase
H1R14_RS09080	COG0857	belongs to the CobB CobQ family
H1R14_RS09085	COG1288	antiporter activity
H1R14_RS09090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H1R14_RS09095	COG0622	Phosphoesterase
H1R14_RS09100	COG0625	glutathione transferase activity
H1R14_RS09105	COG0625	glutathione transferase activity
H1R14_RS09110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H1R14_RS09115	COG1090	epimerase
H1R14_RS09120	COG5464	transposase or invertase
H1R14_RS09125	COG4598	ABC transporter
H1R14_RS09130	COG4160	amino acid transport
H1R14_RS09135	COG4215	(ABC) transporter
H1R14_RS09140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS09145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS09150	COG0163	prenyltransferase activity
H1R14_RS09155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H1R14_RS09160	COG1286	toxin biosynthetic process
H1R14_RS09165	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H1R14_RS09170	COG0285	dihydrofolate synthase activity
H1R14_RS09180	COG0586	Pfam SNARE associated Golgi protein
H1R14_RS09190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1R14_RS09205	COG2814	Major facilitator Superfamily
H1R14_RS09210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1R14_RS09225	COG3101	peptidyl-lysine hydroxylation
H1R14_RS09230	COG0730	response to heat
H1R14_RS09245	COG2890	protein-(glutamine-N5) methyltransferase activity
H1R14_RS09260	COG3539	Fimbrial protein
H1R14_RS09265	COG3539	Fimbrial protein
H1R14_RS09270	COG3539	Fimbrial protein
H1R14_RS09275	COG3121	Chaperone
H1R14_RS09280	COG3188	usher protein
H1R14_RS09285	COG3539	Fimbrial protein
H1R14_RS09290	COG2062	phosphohistidine phosphatase, SixA
H1R14_RS09305	COG3691	Protein conserved in bacteria
H1R14_RS09310	COG2067	long-chain fatty acid transport protein
H1R14_RS09320	COG2853	Lipoprotein
H1R14_RS09325	COG2116	formate transmembrane transporter activity
H1R14_RS09335	COG0582	viral genome integration into host DNA
H1R14_RS09340	COG2246	polysaccharide biosynthetic process
H1R14_RS09580	COG4712	double-strand break repair protein
H1R14_RS09585	COG0629	single-stranded DNA binding
H1R14_RS09630	COG0583	DNA-binding transcription factor activity
H1R14_RS09635	COG2610	gluconate transmembrane transporter activity
H1R14_RS09645	COG0477	Major facilitator Superfamily
H1R14_RS09650	COG1566	PFAM secretion protein HlyD family protein
H1R14_RS09655	COG2197	response regulator
H1R14_RS09660	COG0784	Response regulator, receiver
H1R14_RS09660	COG2205	protein histidine kinase activity
H1R14_RS09660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS09660	COG2198	Histidine kinase
H1R14_RS09665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1R14_RS09670	COG0679	Auxin Efflux Carrier
H1R14_RS09675	COG0028	Belongs to the TPP enzyme family
H1R14_RS09700	COG1560	Kdo2-lipid A biosynthetic process
H1R14_RS09710	COG0436	Aminotransferase
H1R14_RS09715	COG3275	phosphorelay sensor kinase activity
H1R14_RS09720	COG3279	Response regulator of the LytR AlgR family
H1R14_RS09725	COG2207	Transcriptional regulator
H1R14_RS09730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1R14_RS09730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS09730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS09735	COG1363	Peptidase, m42
H1R14_RS09740	COG0006	proline dipeptidase activity
H1R14_RS09745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS09750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS09775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1R14_RS09785	COG2200	EAL domain
H1R14_RS09785	COG2199	diguanylate cyclase activity
H1R14_RS09800	COG3415	Transposase
H1R14_RS09805	COG3415	Transposase
H1R14_RS09835	COG0583	DNA-binding transcription factor activity
H1R14_RS09845	COG2211	Major facilitator Superfamily
H1R14_RS09850	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H1R14_RS09860	COG0583	DNA-binding transcription factor activity
H1R14_RS09865	COG0385	Bile acid
H1R14_RS09870	COG3530	Putative quorum-sensing-regulated virulence factor
H1R14_RS09890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1R14_RS09895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS09900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1R14_RS09905	COG2190	(PTS) system
H1R14_RS09920	COG4884	unkown
H1R14_RS09920	COG3831	ATPase activity
H1R14_RS09925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1R14_RS09930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1R14_RS09935	COG4208	sulfate ABC transporter
H1R14_RS09940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1R14_RS09945	COG4150	thiosulfate binding
H1R14_RS09950	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS09965	COG1263	PTS System
H1R14_RS09965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS09970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1R14_RS09975	COG2837	iron assimilation
H1R14_RS09990	COG0456	acetyltransferase
H1R14_RS09995	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1R14_RS10005	COG2207	Transcriptional regulator
H1R14_RS10010	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H1R14_RS10015	COG4816	utilization protein
H1R14_RS10025	COG4303	Ethanolamine ammonia lyase large subunit
H1R14_RS10030	COG4819	ethanolamine utilization protein
H1R14_RS10035	COG3192	ethanolamine utilization protein
H1R14_RS10040	COG1454	alcohol dehydrogenase
H1R14_RS10045	COG4820	ethanolamine utilization protein (EutJ)
H1R14_RS10050	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS10055	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
H1R14_RS10060	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H1R14_RS10065	COG0280	phosphate acetyltransferase
H1R14_RS10070	COG4812	Cobalamin adenosyltransferase
H1R14_RS10075	COG4766	ethanolamine catabolic process
H1R14_RS10080	COG4917	ethanolamine utilization protein
H1R14_RS10085	COG4810	utilization protein
H1R14_RS10090	COG0281	malic enzyme
H1R14_RS10090	COG0280	phosphate acetyltransferase
H1R14_RS10095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1R14_RS10100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1R14_RS10105	COG5342	invasion associated locus B
H1R14_RS10115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS10115	COG0493	'glutamate synthase
H1R14_RS10120	COG3850	Histidine kinase
H1R14_RS10125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1R14_RS10135	COG1393	Belongs to the ArsC family
H1R14_RS10150	COG0400	carboxylic ester hydrolase activity
H1R14_RS10155	COG1444	tRNA N-acetyltransferase activity
H1R14_RS10160	COG2321	neutral zinc metallopeptidase
H1R14_RS10170	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H1R14_RS10180	COG2716	regulation of RNA biosynthetic process
H1R14_RS10185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1R14_RS10190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS10195	COG0651	ATP synthesis coupled electron transport
H1R14_RS10200	COG0650	Formate hydrogenlyase subunit 4
H1R14_RS10205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1R14_RS10210	COG4237	Hydrogenase 4 membrane
H1R14_RS10215	COG0651	ATP synthesis coupled electron transport
H1R14_RS10220	COG3261	NADH dehydrogenase
H1R14_RS10220	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H1R14_RS10225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1R14_RS10230	COG3260	NADH ubiquinone oxidoreductase 20
H1R14_RS10240	COG3604	Transcriptional regulator
H1R14_RS10245	COG2116	formate transmembrane transporter activity
H1R14_RS10250	COG0628	permease
H1R14_RS10255	COG4783	chaperone-mediated protein folding
H1R14_RS10260	COG1393	Belongs to the ArsC family
H1R14_RS10270	COG2233	PERMEase
H1R14_RS10285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1R14_RS10290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H1R14_RS10295	COG0248	Ppx GppA phosphatase
H1R14_RS10300	COG2200	EAL domain
H1R14_RS10315	COG3133	Outer membrane lipoprotein
H1R14_RS10330	COG0516	GMP reductase activity
H1R14_RS10330	COG0517	IMP dehydrogenase activity
H1R14_RS10340	COG1645	bacterial-type flagellum-dependent swarming motility
H1R14_RS10355	COG2976	Protein conserved in bacteria
H1R14_RS10385	COG4953	penicillin-binding protein 1C
H1R14_RS10390	COG2373	Large extracellular alpha-helical protein
H1R14_RS10395	COG2897	thiosulfate sulfurtransferase activity
H1R14_RS10410	COG2975	iron-sulfur cluster assembly
H1R14_RS10415	COG0633	Ferredoxin
H1R14_RS10435	COG0822	iron-sulfur transferase activity
H1R14_RS10455	COG0483	inositol monophosphate 1-phosphatase activity
H1R14_RS10460	COG1073	alpha beta
H1R14_RS10465	COG3711	transcriptional antiterminator
H1R14_RS10470	COG2814	Major facilitator Superfamily
H1R14_RS10475	COG0583	DNA-binding transcription factor activity
H1R14_RS10480	COG4638	Rieske (2fe-2S)
H1R14_RS10505	COG2259	Doxx family
H1R14_RS10510	COG2017	converts alpha-aldose to the beta-anomer
H1R14_RS10515	COG1063	alcohol dehydrogenase
H1R14_RS10520	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS10525	COG1129	ABC transporter
H1R14_RS10530	COG1879	ABC-type sugar transport system periplasmic component
H1R14_RS10535	COG0457	Tetratricopeptide repeat
H1R14_RS10540	COG1940	carbohydrate kinase activity
H1R14_RS10550	COG1017	nitric oxide dioxygenase activity
H1R14_RS10550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1R14_RS10555	COG0347	Belongs to the P(II) protein family
H1R14_RS10560	COG2204	response regulator
H1R14_RS10565	COG3170	Tfp pilus assembly protein FimV
H1R14_RS10570	COG2205	protein histidine kinase activity
H1R14_RS10575	COG0047	phosphoribosylformylglycinamidine synthase activity
H1R14_RS10575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1R14_RS10590	COG0560	Phosphoserine phosphatase
H1R14_RS10595	COG1737	Transcriptional regulator
H1R14_RS10600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS10615	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1R14_RS10635	COG0681	Belongs to the peptidase S26 family
H1R14_RS10645	COG3086	response to oxidative stress
H1R14_RS10650	COG3026	antisigma factor binding
H1R14_RS10655	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H1R14_RS10660	COG1595	DNA-templated transcription, initiation
H1R14_RS10670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H1R14_RS10680	COG0513	Belongs to the DEAD box helicase family
H1R14_RS10685	COG0583	DNA-binding transcription factor activity
H1R14_RS10705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1R14_RS10710	COG3118	belongs to the thioredoxin family
H1R14_RS10720	COG0045	succinate-CoA ligase (ADP-forming) activity
H1R14_RS10720	COG1042	CoA-binding domain protein
H1R14_RS10720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1R14_RS10725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1R14_RS10730	COG5544	Lipoprotein
H1R14_RS10735	COG0477	Major facilitator Superfamily
H1R14_RS10760	COG0542	response to heat
H1R14_RS10770	COG0564	pseudouridine synthase activity
H1R14_RS10775	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1R14_RS10780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H1R14_RS10790	COG0077	Prephenate dehydratase
H1R14_RS10790	COG1605	Chorismate mutase
H1R14_RS10795	COG0287	Prephenate dehydrogenase
H1R14_RS10795	COG1605	Chorismate mutase
H1R14_RS10800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1R14_RS10815	COG2199	diguanylate cyclase activity
H1R14_RS10820	COG2885	chlorophyll binding
H1R14_RS10845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1R14_RS10850	COG4137	Cytochrome C assembly protein
H1R14_RS10855	COG4536	flavin adenine dinucleotide binding
H1R14_RS10870	COG0497	DNA recombination
H1R14_RS10875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1R14_RS10885	COG2867	negative regulation of translational initiation
H1R14_RS10900	COG0582	viral genome integration into host DNA
H1R14_RS10920	COG0366	Alpha amylase catalytic
H1R14_RS10935	COG0579	oxidoreductase
H1R14_RS10940	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS10945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1R14_RS10950	COG1113	amino acid transport
H1R14_RS10955	COG1802	Transcriptional regulator
H1R14_RS10960	COG1652	LysM domain
H1R14_RS10965	COG0401	homolog of Blt101
H1R14_RS10970	COG0640	Transcriptional regulator
H1R14_RS10975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1R14_RS10980	COG2916	Histone family protein nucleoid-structuring protein H-NS
H1R14_RS10995	COG4575	ribosome binding
H1R14_RS11000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1R14_RS11010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1R14_RS11015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1R14_RS11020	COG4175	Glycine betaine
H1R14_RS11025	COG4176	ABC-type proline glycine betaine transport system permease component
H1R14_RS11030	COG2113	Glycine betaine
H1R14_RS11035	COG2814	Major facilitator Superfamily
H1R14_RS11040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1R14_RS11050	COG1846	Transcriptional regulator
H1R14_RS11055	COG1566	PFAM secretion protein HlyD family protein
H1R14_RS11060	COG2814	Major facilitator Superfamily
H1R14_RS11075	COG1238	metal cluster binding
H1R14_RS11080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1R14_RS11110	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H1R14_RS11130	COG1546	Belongs to the CinA family
H1R14_RS11135	COG2951	lytic endotransglycosylase activity
H1R14_RS11140	COG3730	PTS system glucitol sorbitol-specific
H1R14_RS11150	COG3731	PTS system glucitol sorbitol-specific IIA component
H1R14_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS11160	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS11165	COG1349	DNA-binding transcription factor activity
H1R14_RS11170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1R14_RS11170	COG0517	IMP dehydrogenase activity
H1R14_RS11190	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H1R14_RS11195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS11200	COG1609	Transcriptional regulator
H1R14_RS11205	COG1263	PTS System
H1R14_RS11205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS11210	COG2723	6-phospho-beta-galactosidase activity
H1R14_RS11215	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H1R14_RS11225	COG3260	NADH ubiquinone oxidoreductase 20
H1R14_RS11230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1R14_RS11235	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H1R14_RS11235	COG3261	NADH dehydrogenase
H1R14_RS11240	COG0650	Formate hydrogenlyase subunit 4
H1R14_RS11245	COG0651	ATP synthesis coupled electron transport
H1R14_RS11250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS11260	COG0375	protein maturation
H1R14_RS11265	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H1R14_RS11270	COG0298	carbon dioxide binding
H1R14_RS11275	COG0409	Hydrogenase expression formation protein
H1R14_RS11280	COG0309	Hydrogenase expression formation protein (HypE)
H1R14_RS11285	COG3604	Transcriptional regulator
H1R14_RS11305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1R14_RS11310	COG1349	DNA-binding transcription factor activity
H1R14_RS11315	COG2084	Dehydrogenase
H1R14_RS11320	COG3395	kinase activity
H1R14_RS11325	COG0235	Class ii aldolase
H1R14_RS11330	COG3622	Belongs to the hyi family
H1R14_RS11335	COG2610	gluconate transmembrane transporter activity
H1R14_RS11340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1R14_RS11345	COG4942	peptidase
H1R14_RS11345	COG1388	LysM domain
H1R14_RS11400	COG2234	aminopeptidase activity
H1R14_RS11405	COG3385	transposase activity
H1R14_RS11420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1R14_RS11430	COG0720	synthase
H1R14_RS11435	COG0644	oxidoreductase
H1R14_RS11440	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1R14_RS11445	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H1R14_RS11450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H1R14_RS11455	COG2086	electron transfer activity
H1R14_RS11460	COG0477	Major facilitator Superfamily
H1R14_RS11465	COG0277	FAD linked oxidase domain protein
H1R14_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS11475	COG2223	nitrite transmembrane transporter activity
H1R14_RS11480	COG1070	Carbohydrate kinase
H1R14_RS11485	COG0602	queuosine metabolic process
H1R14_RS11495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1R14_RS11510	COG3956	TIGRFAM MazG family protein
H1R14_RS11515	COG2337	Toxic component of a toxin-antitoxin (TA) module
H1R14_RS11520	COG2336	PFAM SpoVT AbrB
H1R14_RS11525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1R14_RS11530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H1R14_RS11535	COG2205	protein histidine kinase activity
H1R14_RS11535	COG4999	Histidine kinase
H1R14_RS11535	COG3437	response regulator, receiver
H1R14_RS11535	COG3850	Histidine kinase
H1R14_RS11540	COG4948	Mandelate Racemase Muconate Lactonizing
H1R14_RS11545	COG4948	Mandelate Racemase Muconate Lactonizing
H1R14_RS11550	COG2271	Major facilitator Superfamily
H1R14_RS11555	COG0716	FMN binding
H1R14_RS11560	COG0564	pseudouridine synthase activity
H1R14_RS11565	COG3098	single-species biofilm formation
H1R14_RS11580	COG1611	Belongs to the LOG family
H1R14_RS11585	COG0814	amino acid
H1R14_RS11590	COG1760	l-serine dehydratase
H1R14_RS11600	COG1454	alcohol dehydrogenase
H1R14_RS11605	COG0235	Class ii aldolase
H1R14_RS11610	COG0738	Major facilitator superfamily
H1R14_RS11620	COG1070	Carbohydrate kinase
H1R14_RS11630	COG1349	DNA-binding transcription factor activity
H1R14_RS11640	COG2363	Small membrane protein
H1R14_RS11645	COG0583	DNA-binding transcription factor activity
H1R14_RS11655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1R14_RS11660	COG2166	iron-sulfur cluster assembly
H1R14_RS11665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1R14_RS11670	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H1R14_RS11690	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1R14_RS11695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H1R14_RS11695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H1R14_RS11700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1R14_RS11705	COG1074	ATP-dependent DNA helicase activity
H1R14_RS11715	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1R14_RS11720	COG4967	type IV pilus modification protein PilV
H1R14_RS11730	COG4795	General secretion pathway protein
H1R14_RS11735	COG2165	general secretion pathway protein
H1R14_RS11750	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
H1R14_RS11765	COG0861	Integral membrane protein TerC family
H1R14_RS11775	COG0667	Aldo Keto reductase
H1R14_RS11790	COG1609	Transcriptional regulator
H1R14_RS11800	COG0583	DNA-binding transcription factor activity
H1R14_RS11805	COG1794	racemase activity, acting on amino acids and derivatives
H1R14_RS11810	COG2814	Major facilitator Superfamily
H1R14_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS11825	COG0183	Belongs to the thiolase family
H1R14_RS11830	COG0814	amino acid
H1R14_RS11840	COG3710	Transcriptional regulator
H1R14_RS11865	COG0457	Tetratricopeptide repeat
H1R14_RS11870	COG0457	Tetratricopeptide repeat
H1R14_RS11870	COG3710	Transcriptional regulator
H1R14_RS11980	COG4942	peptidase
H1R14_RS11985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1R14_RS11990	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H1R14_RS11995	COG2080	2 iron, 2 sulfur cluster binding
H1R14_RS12005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1R14_RS12010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1R14_RS12015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1R14_RS12025	COG0549	Belongs to the carbamate kinase family
H1R14_RS12030	COG3608	succinylglutamate desuccinylase aspartoacylase
H1R14_RS12030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H1R14_RS12035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1R14_RS12040	COG2068	MobA-Related Protein
H1R14_RS12045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS12045	COG0493	'glutamate synthase
H1R14_RS12050	COG0402	S-adenosylhomocysteine deaminase activity
H1R14_RS12055	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H1R14_RS12060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1R14_RS12060	COG2080	2 iron, 2 sulfur cluster binding
H1R14_RS12065	COG2233	PERMEase
H1R14_RS12070	COG0402	S-adenosylhomocysteine deaminase activity
H1R14_RS12075	COG2252	PERMEase
H1R14_RS12080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS12090	COG2233	PERMEase
H1R14_RS12110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H1R14_RS12120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1R14_RS12125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1R14_RS12130	COG4974	Belongs to the 'phage' integrase family
H1R14_RS12135	COG0716	FMN binding
H1R14_RS12145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1R14_RS12155	COG1272	protein, Hemolysin III
H1R14_RS12165	COG2723	6-phospho-beta-galactosidase activity
H1R14_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS12195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1R14_RS12200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1R14_RS12205	COG0006	proline dipeptidase activity
H1R14_RS12225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1R14_RS12235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1R14_RS12255	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H1R14_RS12255	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H1R14_RS12260	COG1703	isobutyryl-CoA mutase activity
H1R14_RS12265	COG1024	Enoyl-CoA hydratase
H1R14_RS12270	COG0427	acetyl-CoA hydrolase
H1R14_RS12275	COG0583	DNA-binding transcription factor activity
H1R14_RS12280	COG2968	Membrane
H1R14_RS12285	COG1279	arginine transmembrane transporter activity
H1R14_RS12290	COG0668	transmembrane transport
H1R14_RS12295	COG0191	fructose-bisphosphate aldolase activity
H1R14_RS12310	COG1072	(Pantothenic acid kinase))
H1R14_RS12315	COG3722	fumarate hydratase activity
H1R14_RS12320	COG1494	fructose-1,6-bisphosphatase
H1R14_RS12325	COG1063	alcohol dehydrogenase
H1R14_RS12330	COG2213	PTS system mannitol-specific
H1R14_RS12335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS12340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1R14_RS12345	COG0501	Belongs to the peptidase M48B family
H1R14_RS12355	COG1166	arginine decarboxylase activity
H1R14_RS12375	COG2814	Major facilitator Superfamily
H1R14_RS12385	COG2356	endonuclease I
H1R14_RS12390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1R14_RS12395	COG0189	ligase activity
H1R14_RS12410	COG2805	Type II/IV secretion system protein
H1R14_RS12415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H1R14_RS12420	COG0762	integral membrane protein
H1R14_RS12430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H1R14_RS12435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1R14_RS12445	COG0252	asparaginase activity
H1R14_RS12455	COG3171	Protein conserved in bacteria
H1R14_RS12465	COG1194	a g-specific adenine glycosylase
H1R14_RS12480	COG2211	Major facilitator Superfamily
H1R14_RS12485	COG1982	Orn Lys Arg decarboxylase major
H1R14_RS12490	COG1811	Na channel or pump
H1R14_RS12500	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H1R14_RS12515	COG4795	General secretion pathway protein
H1R14_RS12530	COG2165	general secretion pathway protein
H1R14_RS12535	COG1459	type II secretion system
H1R14_RS12540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1R14_RS12550	COG1620	l-lactate permease
H1R14_RS12555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1R14_RS12560	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H1R14_RS12565	COG0247	lactate metabolic process
H1R14_RS12570	COG0277	FAD linked oxidase domain protein
H1R14_RS12575	COG0277	FAD linked oxidase domain protein
H1R14_RS12580	COG2186	Transcriptional regulator
H1R14_RS12585	COG0456	acetyltransferase
H1R14_RS12590	COG0318	PFAM AMP-dependent synthetase and ligase
H1R14_RS12600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1R14_RS12605	COG0156	8-amino-7-oxononanoate synthase activity
H1R14_RS12615	COG0795	lipopolysaccharide-transporting ATPase activity
H1R14_RS12620	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H1R14_RS12630	COG2244	polysaccharide biosynthetic process
H1R14_RS12635	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H1R14_RS12640	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H1R14_RS12645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H1R14_RS12650	COG0306	phosphate transporter
H1R14_RS12655	COG0754	glutathionylspermidine amidase activity
H1R14_RS12660	COG0625	glutathione transferase activity
H1R14_RS12665	COG0298	carbon dioxide binding
H1R14_RS12675	COG1773	rubredoxin
H1R14_RS12680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H1R14_RS12685	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H1R14_RS12690	COG5557	Pfam Polysulphide reductase, NrfD
H1R14_RS12695	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS12700	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H1R14_RS12715	COG0667	Aldo Keto reductase
H1R14_RS12725	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS12730	COG0848	biopolymer transport protein
H1R14_RS12735	COG0811	peptide transport
H1R14_RS12740	COG0626	cystathionine gamma-synthase activity
H1R14_RS12745	COG0586	Pfam SNARE associated Golgi protein
H1R14_RS12750	COG2207	Transcriptional regulator
H1R14_RS12755	COG1979	alcohol dehydrogenase
H1R14_RS12760	COG0656	L-ascorbic acid biosynthetic process
H1R14_RS12770	COG4238	major outer membrane lipoprotein
H1R14_RS12775	COG1032	radical SAM domain protein
H1R14_RS12780	COG2132	Multicopper oxidase
H1R14_RS12785	COG0204	Acyl-transferase
H1R14_RS12790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H1R14_RS12795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1R14_RS12800	COG3111	PFAM Bacterial OB fold (BOF) protein
H1R14_RS12805	COG0745	RESPONSE REGULATOR receiver
H1R14_RS12810	COG0642	Histidine kinase
H1R14_RS12815	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1R14_RS12820	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1R14_RS12825	COG1737	Transcriptional regulator
H1R14_RS12835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R14_RS12845	COG1120	ATPase activity
H1R14_RS12850	COG4774	siderophore transport
H1R14_RS12855	COG0187	DNA topoisomerase II activity
H1R14_RS12860	COG3150	esterase
H1R14_RS12865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1R14_RS12870	COG3151	Protein conserved in bacteria
H1R14_RS12875	COG0494	nUDIX hydrolase
H1R14_RS12880	COG1538	Outer membrane efflux protein
H1R14_RS12890	COG0754	glutathionylspermidine amidase activity
H1R14_RS12895	COG3384	dioxygenase
H1R14_RS12910	COG3539	Fimbrial protein
H1R14_RS12915	COG3188	usher protein
H1R14_RS12920	COG3121	Chaperone
H1R14_RS12925	COG3539	Fimbrial protein
H1R14_RS12945	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1R14_RS12955	COG2268	Band 7 protein
H1R14_RS12980	COG3025	triphosphatase activity
H1R14_RS12985	COG4991	sh3 domain protein
H1R14_RS13000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H1R14_RS13015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1R14_RS13020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1R14_RS13035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H1R14_RS13040	COG0358	DNA primase activity
H1R14_RS13045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1R14_RS13060	COG2375	cellular response to nickel ion
H1R14_RS13065	COG1695	Transcriptional regulator
H1R14_RS13070	COG0840	transmembrane signaling receptor activity
H1R14_RS13080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1R14_RS13085	COG1609	Transcriptional regulator
H1R14_RS13090	COG3250	beta-galactosidase activity
H1R14_RS13095	COG2731	YhcH YjgK YiaL family protein
H1R14_RS13100	COG0531	amino acid
H1R14_RS13110	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H1R14_RS13110	COG3408	Glycogen debranching enzyme
H1R14_RS13115	COG1902	pentaerythritol trinitrate reductase activity
H1R14_RS13115	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1R14_RS13120	COG5499	transcription regulator containing HTH domain
H1R14_RS13125	COG4680	protein conserved in bacteria
H1R14_RS13135	COG1451	nucleotide metabolic process
H1R14_RS13140	COG2949	membrane
H1R14_RS13145	COG0673	inositol 2-dehydrogenase activity
H1R14_RS13150	COG0861	Integral membrane protein TerC family
H1R14_RS13155	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H1R14_RS13165	COG2721	sulfolactate sulfo-lyase activity
H1R14_RS13175	COG2271	Major facilitator Superfamily
H1R14_RS13180	COG2186	Transcriptional regulator
H1R14_RS13185	COG0586	Pfam SNARE associated Golgi protein
H1R14_RS13195	COG1422	Protein of unknown function (DUF1090)
H1R14_RS13200	COG4575	ribosome binding
H1R14_RS13205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H1R14_RS13215	COG2259	Doxx family
H1R14_RS13220	COG0435	Glutathione S-transferase
H1R14_RS13225	COG3152	Membrane
H1R14_RS13230	COG3152	Membrane
H1R14_RS13235	COG0583	DNA-binding transcription factor activity
H1R14_RS13240	COG1741	Belongs to the pirin family
H1R14_RS13255	COG0814	amino acid
H1R14_RS13260	COG1760	l-serine dehydratase
H1R14_RS13265	COG0251	oxidation-reduction process
H1R14_RS13270	COG1882	Formate acetyltransferase
H1R14_RS13275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1R14_RS13285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1R14_RS13290	COG0583	DNA-binding transcription factor activity
H1R14_RS13315	COG1929	Belongs to the glycerate kinase type-1 family
H1R14_RS13320	COG2084	Dehydrogenase
H1R14_RS13330	COG2271	Major facilitator Superfamily
H1R14_RS13335	COG2721	sulfolactate sulfo-lyase activity
H1R14_RS13340	COG2002	toxin-antitoxin pair type II binding
H1R14_RS13350	COG1349	DNA-binding transcription factor activity
H1R14_RS13360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS13370	COG3716	PTS system mannose fructose sorbose family IID component
H1R14_RS13375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS13380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1R14_RS13385	COG2222	sugar isomerase
H1R14_RS13395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS13400	COG3715	PTS system
H1R14_RS13405	COG3716	PTS system mannose fructose sorbose family IID component
H1R14_RS13410	COG0363	glucosamine-6-phosphate deaminase activity
H1R14_RS13415	COG3539	Fimbrial protein
H1R14_RS13420	COG3121	Chaperone
H1R14_RS13425	COG3188	usher protein
H1R14_RS13430	COG3539	Fimbrial protein
H1R14_RS13435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H1R14_RS13440	COG3107	peptidoglycan biosynthetic process
H1R14_RS13455	COG2823	Periplasmic or secreted lipoprotein
H1R14_RS13460	COG0701	Predicted permease
H1R14_RS13465	COG0702	epimerase
H1R14_RS13470	COG0693	protein deglycase activity
H1R14_RS13485	COG3153	acetyltransferase
H1R14_RS13490	COG3154	lipid carrier protein
H1R14_RS13495	COG0826	peptidase U32
H1R14_RS13500	COG0826	peptidase U32
H1R14_RS13505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1R14_RS13510	COG0814	amino acid
H1R14_RS13515	COG0513	Belongs to the DEAD box helicase family
H1R14_RS13555	COG0195	Participates in both transcription termination and antitermination
H1R14_RS13575	COG2194	sulfuric ester hydrolase activity
H1R14_RS13585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H1R14_RS13595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1R14_RS13600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1R14_RS13610	COG1534	Rna-binding protein
H1R14_RS13615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1R14_RS13620	COG2027	D-alanyl-D-alanine carboxypeptidase
H1R14_RS13630	COG0697	spore germination
H1R14_RS13645	COG0142	geranyltranstransferase activity
H1R14_RS13650	COG3423	Transcriptional regulator
H1R14_RS13660	COG5007	Belongs to the BolA IbaG family
H1R14_RS13665	COG3113	response to antibiotic
H1R14_RS13670	COG2854	intermembrane phospholipid transfer
H1R14_RS13675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1R14_RS13680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1R14_RS13685	COG1127	ABC transporter
H1R14_RS13690	COG0530	calcium, potassium:sodium antiporter activity
H1R14_RS13695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1R14_RS13695	COG0517	IMP dehydrogenase activity
H1R14_RS13700	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1R14_RS13705	COG3117	lipopolysaccharide transmembrane transporter activity
H1R14_RS13710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1R14_RS13715	COG1137	ATPase activity
H1R14_RS13720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H1R14_RS13725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H1R14_RS13740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS13745	COG0515	serine threonine protein kinase
H1R14_RS13755	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H1R14_RS13760	COG2198	Histidine kinase
H1R14_RS13760	COG5002	protein histidine kinase activity
H1R14_RS13760	COG0784	Response regulator, receiver
H1R14_RS13765	COG1242	4 iron, 4 sulfur cluster binding
H1R14_RS13770	COG0067	glutamate synthase
H1R14_RS13770	COG0069	glutamate synthase activity
H1R14_RS13770	COG0070	glutamate synthase
H1R14_RS13775	COG0493	'glutamate synthase
H1R14_RS13780	COG3539	Fimbrial protein
H1R14_RS13785	COG3121	Chaperone
H1R14_RS13790	COG3188	usher protein
H1R14_RS13800	COG3539	Fimbrial protein
H1R14_RS13805	COG4804	nuclease activity
H1R14_RS13810	COG2731	YhcH YjgK YiaL family protein
H1R14_RS13840	COG3069	C4-dicarboxylate transmembrane transporter activity
H1R14_RS13845	COG2969	positive regulation of protein catabolic process
H1R14_RS13850	COG0625	glutathione transferase activity
H1R14_RS13865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1R14_RS13870	COG3105	Protein conserved in bacteria
H1R14_RS13875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1R14_RS13880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1R14_RS13900	COG2732	(Barnase) inhibitor
H1R14_RS13920	COG0583	DNA-binding transcription factor activity
H1R14_RS13925	COG0312	modulator of DNA gyrase
H1R14_RS13930	COG3164	Protein of unknown function
H1R14_RS13935	COG1530	ribonuclease E activity
H1R14_RS13940	COG0424	maF-like protein
H1R14_RS13945	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1R14_RS13950	COG1792	Involved in formation and maintenance of cell shape
H1R14_RS13955	COG1077	Cell shape determining protein MreB Mrl
H1R14_RS13960	COG2200	EAL domain
H1R14_RS13960	COG2199	diguanylate cyclase activity
H1R14_RS13965	COG0604	alcohol dehydrogenase
H1R14_RS13970	COG0511	ligase activity, forming carbon-carbon bonds
H1R14_RS13975	COG0439	Biotin carboxylase
H1R14_RS13980	COG3924	membrane
H1R14_RS13985	COG4145	pantothenate transmembrane transporter activity
H1R14_RS13995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1R14_RS14005	COG2189	Belongs to the N(4) N(6)-methyltransferase family
H1R14_RS14015	COG1309	transcriptional regulator
H1R14_RS14020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS14025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1R14_RS14035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS14040	COG4597	amino acid ABC transporter
H1R14_RS14045	COG0765	amino acid transport
H1R14_RS14050	COG1126	abc transporter atp-binding protein
H1R14_RS14090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1R14_RS14110	COG0551	DNA topoisomerase type I activity
H1R14_RS14120	COG0758	DNA mediated transformation
H1R14_RS14140	COG0569	domain protein
H1R14_RS14150	COG3036	rescue of stalled ribosome
H1R14_RS14155	COG0789	Transcriptional regulator
H1R14_RS14195	COG0201	protein transport
H1R14_RS14285	COG0089	rRNA binding
H1R14_RS14310	COG3409	Peptidoglycan-binding domain 1 protein
H1R14_RS14310	COG3267	Type II secretory pathway component ExeA
H1R14_RS14315	COG3031	protein transport across the cell outer membrane
H1R14_RS14320	COG1450	Type ii and iii secretion system protein
H1R14_RS14325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1R14_RS14335	COG2165	general secretion pathway protein
H1R14_RS14340	COG2165	general secretion pathway protein
H1R14_RS14345	COG2165	general secretion pathway protein
H1R14_RS14350	COG4795	General secretion pathway protein
H1R14_RS14355	COG3156	type II secretion system protein K
H1R14_RS14360	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H1R14_RS14365	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H1R14_RS14370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H1R14_RS14375	COG2193	ferroxidase activity
H1R14_RS14380	COG2906	2 iron, 2 sulfur cluster binding
H1R14_RS14385	COG3979	chitinase
H1R14_RS14425	COG2964	Protein conserved in bacteria
H1R14_RS14430	COG0545	Peptidyl-prolyl cis-trans isomerase
H1R14_RS14440	COG1047	Peptidyl-prolyl cis-trans
H1R14_RS14445	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1R14_RS14460	COG0488	(ABC) transporter
H1R14_RS14465	COG0429	hydrolase of the alpha beta-hydrolase fold
H1R14_RS14475	COG3954	Phosphoribulokinase
H1R14_RS14480	COG1765	OsmC-like protein
H1R14_RS14485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1R14_RS14490	COG1289	transmembrane transporter activity
H1R14_RS14495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1R14_RS14500	COG0512	Glutamine amidotransferase of anthranilate synthase
H1R14_RS14505	COG2184	nucleotidyltransferase activity
H1R14_RS14515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1R14_RS14525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1R14_RS14530	COG2146	nitrite reductase [NAD(P)H] activity
H1R14_RS14535	COG2116	formate transmembrane transporter activity
H1R14_RS14550	COG0531	amino acid
H1R14_RS14555	COG2222	sugar isomerase
H1R14_RS14560	COG1082	Xylose isomerase domain protein TIM barrel
H1R14_RS14565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS14570	COG2188	Transcriptional regulator
H1R14_RS14575	COG0626	cystathionine gamma-synthase activity
H1R14_RS14595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H1R14_RS14600	COG3457	Alanine racemase
H1R14_RS14610	COG2188	Transcriptional regulator
H1R14_RS14615	COG0180	Tryptophanyl-tRNA synthetase
H1R14_RS14620	COG0546	phosphoglycolate phosphatase activity
H1R14_RS14625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1R14_RS14630	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H1R14_RS14635	COG3266	domain, Protein
H1R14_RS14650	COG4796	Type ii and iii secretion system protein
H1R14_RS14665	COG3166	PFAM Fimbrial assembly family protein
H1R14_RS14670	COG4972	Pilus assembly protein
H1R14_RS14675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H1R14_RS14680	COG0494	nUDIX hydrolase
H1R14_RS14690	COG1011	Hydrolase
H1R14_RS14695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1R14_RS14705	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1R14_RS14715	COG2205	protein histidine kinase activity
H1R14_RS14720	COG0745	RESPONSE REGULATOR receiver
H1R14_RS14725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1R14_RS14730	COG2183	response to ionizing radiation
H1R14_RS14735	COG1918	ferrous iron import across plasma membrane
H1R14_RS14740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H1R14_RS14750	COG5464	transposase or invertase
H1R14_RS14760	COG1040	competence protein
H1R14_RS14770	COG2610	gluconate transmembrane transporter activity
H1R14_RS14775	COG1640	4-alpha-glucanotransferase
H1R14_RS14780	COG0058	SHG alpha-glucan phosphorylase activity
H1R14_RS14795	COG1690	Belongs to the RtcB family
H1R14_RS14800	COG4650	regulator
H1R14_RS14805	COG1349	DNA-binding transcription factor activity
H1R14_RS14820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H1R14_RS14830	COG0058	SHG alpha-glucan phosphorylase activity
H1R14_RS14855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1R14_RS14860	COG2095	MarC family integral membrane protein
H1R14_RS14865	COG2610	gluconate transmembrane transporter activity
H1R14_RS14870	COG3265	gluconokinase activity
H1R14_RS14875	COG1609	Transcriptional regulator
H1R14_RS14880	COG1741	Belongs to the pirin family
H1R14_RS14885	COG0673	inositol 2-dehydrogenase activity
H1R14_RS14890	COG1247	-acetyltransferase
H1R14_RS14910	COG0405	Gamma-glutamyltransferase
H1R14_RS14920	COG0584	glycerophosphoryl diester phosphodiesterase
H1R14_RS14925	COG3842	ATPase activity
H1R14_RS14930	COG0395	ABC-type sugar transport system, permease component
H1R14_RS14935	COG1175	transmembrane transport
H1R14_RS14940	COG1653	transport
H1R14_RS14945	COG0410	ABC transporter
H1R14_RS14950	COG0411	ABC transporter
H1R14_RS14955	COG4177	L-phenylalanine transmembrane transporter activity
H1R14_RS14960	COG0559	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS14965	COG0683	leucine binding
H1R14_RS14970	COG0456	acetyltransferase
H1R14_RS14975	COG0683	leucine binding
H1R14_RS14980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1R14_RS14985	COG2177	Part of the ABC transporter FtsEX involved in
H1R14_RS14990	COG2884	Cell division ATP-binding protein ftsE
H1R14_RS14995	COG0552	protein localization to endoplasmic reticulum
H1R14_RS15000	COG0742	ribosomal rna small subunit methyltransferase
H1R14_RS15005	COG3776	membrane
H1R14_RS15015	COG3714	YhhN family
H1R14_RS15020	COG2217	Heavy metal translocating P-type atpase
H1R14_RS15030	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H1R14_RS15040	COG0477	Major facilitator Superfamily
H1R14_RS15045	COG0628	permease
H1R14_RS15050	COG2091	lysine biosynthetic process via aminoadipic acid
H1R14_RS15055	COG0747	negative chemotaxis
H1R14_RS15060	COG0601	transmembrane transport
H1R14_RS15065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1R14_RS15070	COG0444	Belongs to the ABC transporter superfamily
H1R14_RS15075	COG1124	(ABC) transporter
H1R14_RS15085	COG3209	COG3209 Rhs family protein
H1R14_RS15095	COG1413	lyase activity
H1R14_RS15100	COG5433	transposase activity
H1R14_RS15105	COG0842	Transport permease protein
H1R14_RS15110	COG0842	Transport permease protein
H1R14_RS15110	COG1129	ABC transporter
H1R14_RS15115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS15140	COG2205	protein histidine kinase activity
H1R14_RS15145	COG0745	RESPONSE REGULATOR receiver
H1R14_RS15150	COG1276	copper resistance
H1R14_RS15155	COG2372	response to copper ion
H1R14_RS15160	COG3667	copper resistance
H1R14_RS15165	COG2132	Multicopper oxidase
H1R14_RS15175	COG0739	heme binding
H1R14_RS15205	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS15275	COG2081	HI0933 family
H1R14_RS15280	COG0306	phosphate transporter
H1R14_RS15290	COG0589	response to stress
H1R14_RS15295	COG3104	oligopeptide transport
H1R14_RS15305	COG0339	signal peptide processing
H1R14_RS15310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1R14_RS15315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1R14_RS15325	COG0640	Transcriptional regulator
H1R14_RS15330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1R14_RS15335	COG1393	Belongs to the ArsC family
H1R14_RS15345	COG3065	identical protein binding
H1R14_RS15350	COG2197	response regulator
H1R14_RS15355	COG1285	pathogenesis
H1R14_RS15370	COG3247	response to pH
H1R14_RS15375	COG2771	luxR family
H1R14_RS15385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS15390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1R14_RS15395	COG2207	Transcriptional regulator
H1R14_RS15400	COG2207	Transcriptional regulator
H1R14_RS15405	COG0076	glutamate decarboxylase activity
H1R14_RS15410	COG1858	cytochrome C peroxidase
H1R14_RS15420	COG2197	response regulator
H1R14_RS15425	COG0583	DNA-binding transcription factor activity
H1R14_RS15430	COG1295	ribonuclease BN
H1R14_RS15435	COG0477	Major facilitator Superfamily
H1R14_RS15440	COG2982	Protein involved in outer membrane biogenesis
H1R14_RS15445	COG2200	EAL domain
H1R14_RS15450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS15455	COG0612	Peptidase, M16
H1R14_RS15465	COG2200	EAL domain
H1R14_RS15465	COG2199	diguanylate cyclase activity
H1R14_RS15470	COG3118	belongs to the thioredoxin family
H1R14_RS15470	COG0457	Tetratricopeptide repeat
H1R14_RS15475	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H1R14_RS15480	COG1215	transferase activity, transferring glycosyl groups
H1R14_RS15520	COG0814	amino acid
H1R14_RS15525	COG4608	Belongs to the ABC transporter superfamily
H1R14_RS15530	COG0444	Belongs to the ABC transporter superfamily
H1R14_RS15535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1R14_RS15540	COG0601	transmembrane transport
H1R14_RS15545	COG0747	negative chemotaxis
H1R14_RS15555	COG2194	sulfuric ester hydrolase activity
H1R14_RS15560	COG2223	nitrite transmembrane transporter activity
H1R14_RS15565	COG5571	outer membrane autotransporter
H1R14_RS15570	COG2818	Glycosylase
H1R14_RS15575	COG0456	acetyltransferase
H1R14_RS15580	COG0243	molybdopterin cofactor binding
H1R14_RS15585	COG2885	chlorophyll binding
H1R14_RS15600	COG2944	sequence-specific DNA binding
H1R14_RS15605	COG1278	Cold shock
H1R14_RS15635	COG3274	enterobacterial common antigen metabolic process
H1R14_RS15640	COG4682	membrane
H1R14_RS15645	COG4682	membrane
H1R14_RS15650	COG1070	Carbohydrate kinase
H1R14_RS15660	COG4213	ABC transporter substrate-binding protein
H1R14_RS15665	COG1129	ABC transporter
H1R14_RS15670	COG4214	carbohydrate transport
H1R14_RS15675	COG1609	Transcriptional regulator
H1R14_RS15675	COG2207	Transcriptional regulator
H1R14_RS15680	COG2992	FlgJ-related protein
H1R14_RS15685	COG0366	Alpha amylase catalytic
H1R14_RS15690	COG3977	Valine--pyruvate aminotransferase
H1R14_RS15695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1R14_RS15700	COG1414	Transcriptional regulator
H1R14_RS15710	COG2731	YhcH YjgK YiaL family protein
H1R14_RS15715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1R14_RS15720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1R14_RS15725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1R14_RS15730	COG1070	Carbohydrate kinase
H1R14_RS15735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H1R14_RS15740	COG3623	hexulose-6-phosphate isomerase
H1R14_RS15745	COG0235	Class ii aldolase
H1R14_RS15755	COG3713	MltA-interacting MipA family protein
H1R14_RS15760	COG0583	DNA-binding transcription factor activity
H1R14_RS15765	COG1566	PFAM secretion protein HlyD family protein
H1R14_RS15780	COG1012	belongs to the aldehyde dehydrogenase family
H1R14_RS15785	COG1454	alcohol dehydrogenase
H1R14_RS15790	COG3276	selenocysteine insertion sequence binding
H1R14_RS15800	COG0625	glutathione transferase activity
H1R14_RS15810	COG1413	lyase activity
H1R14_RS15820	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H1R14_RS15830	COG1566	PFAM secretion protein HlyD family protein
H1R14_RS15840	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS15840	COG2213	PTS system mannitol-specific
H1R14_RS15850	COG3722	fumarate hydratase activity
H1R14_RS15865	COG1620	l-lactate permease
H1R14_RS15870	COG2186	Transcriptional regulator
H1R14_RS15880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1R14_RS15885	COG1045	serine acetyltransferase
H1R14_RS15900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1R14_RS15905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1R14_RS15915	COG4942	peptidase
H1R14_RS15920	COG2861	carbohydrate metabolic process
H1R14_RS15925	COG1216	Glycosyl transferase, family 2
H1R14_RS15935	COG0156	8-amino-7-oxononanoate synthase activity
H1R14_RS15945	COG0859	PFAM glycosyl transferase family 9
H1R14_RS15950	COG0859	PFAM glycosyl transferase family 9
H1R14_RS15970	COG3642	lipopolysaccharide core region biosynthetic process
H1R14_RS15975	COG1442	glycosyl transferase family 8
H1R14_RS15980	COG1442	glycosyl transferase family 8
H1R14_RS15985	COG0438	transferase activity, transferring glycosyl groups
H1R14_RS15995	COG0515	serine threonine protein kinase
H1R14_RS16000	COG0438	transferase activity, transferring glycosyl groups
H1R14_RS16005	COG0859	PFAM glycosyl transferase family 9
H1R14_RS16010	COG1519	Transferase
H1R14_RS16040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1R14_RS16065	COG1561	YicC-like family, N-terminal region
H1R14_RS16070	COG3645	SOS response
H1R14_RS16075	COG2860	membrane
H1R14_RS16085	COG0194	GDP metabolic process
H1R14_RS16095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1R14_RS16100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1R14_RS16105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1R14_RS16110	COG0786	glutamate:sodium symporter activity
H1R14_RS16115	COG2233	PERMEase
H1R14_RS16120	COG2982	Protein involved in outer membrane biogenesis
H1R14_RS16125	COG1501	Belongs to the glycosyl hydrolase 31 family
H1R14_RS16130	COG2211	Major facilitator Superfamily
H1R14_RS16140	COG2814	Major facilitator Superfamily
H1R14_RS16145	COG0697	spore germination
H1R14_RS16150	COG1464	Belongs to the NlpA lipoprotein family
H1R14_RS16170	COG2252	PERMEase
H1R14_RS16180	COG2271	Major facilitator Superfamily
H1R14_RS16185	COG2271	Major facilitator Superfamily
H1R14_RS16190	COG3851	Histidine kinase
H1R14_RS16195	COG2197	response regulator
H1R14_RS16200	COG0440	acetolactate synthase activity
H1R14_RS16205	COG0028	Belongs to the TPP enzyme family
H1R14_RS16220	COG2814	Major facilitator Superfamily
H1R14_RS16225	COG0641	radical SAM
H1R14_RS16235	COG2149	membrane
H1R14_RS16245	COG3119	arylsulfatase activity
H1R14_RS16250	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1R14_RS16255	COG2207	Transcriptional regulator
H1R14_RS16270	COG2188	Transcriptional regulator
H1R14_RS16290	COG5645	(Lipo)protein
H1R14_RS16295	COG0823	Involved in the tonB-independent uptake of proteins
H1R14_RS16300	COG0644	oxidoreductase
H1R14_RS16305	COG2271	Major facilitator Superfamily
H1R14_RS16315	COG0800	Aldolase
H1R14_RS16320	COG3734	2-keto-3-deoxy-galactonokinase
H1R14_RS16325	COG2186	Transcriptional regulator
H1R14_RS16335	COG0561	phosphatase activity
H1R14_RS16340	COG3753	Protein conserved in bacteria
H1R14_RS16345	COG0187	DNA topoisomerase II activity
H1R14_RS16355	COG0592	DNA-directed DNA polymerase activity
H1R14_RS16405	COG0814	amino acid
H1R14_RS16420	COG2091	lysine biosynthetic process via aminoadipic acid
H1R14_RS16425	COG0431	NADPH-dependent FMN reductase
H1R14_RS16430	COG2252	PERMEase
H1R14_RS16435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1R14_RS16445	COG3196	Protein conserved in bacteria
H1R14_RS16450	COG0363	glucosamine-6-phosphate deaminase activity
H1R14_RS16455	COG2382	esterase
H1R14_RS16465	COG2723	6-phospho-beta-galactosidase activity
H1R14_RS16470	COG2190	(PTS) system
H1R14_RS16470	COG1263	PTS System
H1R14_RS16470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS16475	COG3711	transcriptional antiterminator
H1R14_RS16480	COG0704	Plays a role in the regulation of phosphate uptake
H1R14_RS16485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1R14_RS16490	COG0581	inorganic phosphate transmembrane transporter activity
H1R14_RS16495	COG0573	inorganic phosphate transmembrane transporter activity
H1R14_RS16500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1R14_RS16505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1R14_RS16555	COG3312	ion transport
H1R14_RS16570	COG0716	FMN binding
H1R14_RS16575	COG1522	sequence-specific DNA binding
H1R14_RS16605	COG1129	ABC transporter
H1R14_RS16610	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS16615	COG1879	ABC-type sugar transport system periplasmic component
H1R14_RS16620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS16625	COG1609	Transcriptional regulator
H1R14_RS16630	COG0477	Major facilitator Superfamily
H1R14_RS16635	COG2186	Transcriptional regulator
H1R14_RS16675	COG3085	chromosome segregation
H1R14_RS16700	COG3978	acetolactate synthase activity
H1R14_RS16705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1R14_RS16715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1R14_RS16720	COG0583	DNA-binding transcription factor activity
H1R14_RS16730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1R14_RS16740	COG0210	DNA helicase
H1R14_RS16755	COG3118	belongs to the thioredoxin family
H1R14_RS16765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H1R14_RS16770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1R14_RS16775	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H1R14_RS16780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H1R14_RS16785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1R14_RS16790	COG1088	dTDP-glucose 4,6-dehydratase activity
H1R14_RS16795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H1R14_RS16800	COG0456	acetyltransferase
H1R14_RS16805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1R14_RS16810	COG2244	polysaccharide biosynthetic process
H1R14_RS16830	COG1113	amino acid transport
H1R14_RS16855	COG0641	radical SAM
H1R14_RS16860	COG3119	arylsulfatase activity
H1R14_RS16865	COG3071	HemY protein
H1R14_RS16870	COG2959	enzyme of heme biosynthesis
H1R14_RS16875	COG1587	Uroporphyrinogen-III synthase
H1R14_RS16885	COG3072	Adenylate cyclase
H1R14_RS16895	COG5567	small periplasmic lipoprotein
H1R14_RS16905	COG3159	Protein conserved in bacteria
H1R14_RS16915	COG1011	Hydrolase
H1R14_RS16920	COG0210	DNA helicase
H1R14_RS16925	COG3698	Phosphodiester glycosidase
H1R14_RS16930	COG0598	Magnesium transport protein CorA
H1R14_RS16945	COG2962	Rard protein
H1R14_RS16950	COG2050	protein possibly involved in aromatic compounds catabolism
H1R14_RS16955	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
H1R14_RS16960	COG0514	ATP-dependent DNA helicase (RecQ)
H1R14_RS16965	COG1280	lysine exporter protein (LysE YggA)
H1R14_RS16970	COG1280	lysine exporter protein (LysE YggA)
H1R14_RS16975	COG2267	carboxylic ester hydrolase activity
H1R14_RS16980	COG0561	phosphatase activity
H1R14_RS16985	COG0697	spore germination
H1R14_RS16990	COG0583	DNA-binding transcription factor activity
H1R14_RS17000	COG0412	Dienelactone hydrolase
H1R14_RS17005	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H1R14_RS17010	COG1322	Protein conserved in bacteria
H1R14_RS17020	COG3165	ubiquinone biosynthetic process from chorismate
H1R14_RS17030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1R14_RS17035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1R14_RS17040	COG0805	protein transport
H1R14_RS17045	COG0084	hydrolase, TatD family'
H1R14_RS17050	COG0250	Participates in transcription elongation, termination and antitermination
H1R14_RS17055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1R14_RS17060	COG0543	2 iron, 2 sulfur cluster binding
H1R14_RS17065	COG0183	Belongs to the thiolase family
H1R14_RS17080	COG1739	Uncharacterized protein family UPF0029
H1R14_RS17085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1R14_RS17090	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H1R14_RS17120	COG1763	Mo-molybdopterin cofactor biosynthetic process
H1R14_RS17125	COG0746	molybdenum cofactor guanylyltransferase activity
H1R14_RS17130	COG3084	Protein conserved in bacteria
H1R14_RS17135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1R14_RS17140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1R14_RS17145	COG5339	Protein conserved in bacteria
H1R14_RS17150	COG0204	Acyl-transferase
H1R14_RS17155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1R14_RS17155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1R14_RS17170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1R14_RS17180	COG2204	response regulator
H1R14_RS17185	COG3852	Histidine kinase
H1R14_RS17190	COG0174	glutamine synthetase
H1R14_RS17200	COG2188	Transcriptional regulator
H1R14_RS17205	COG1082	Xylose isomerase domain protein TIM barrel
H1R14_RS17210	COG2271	Major facilitator Superfamily
H1R14_RS17215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H1R14_RS17220	COG2211	Major facilitator Superfamily
H1R14_RS17225	COG2211	Major facilitator Superfamily
H1R14_RS17230	COG1501	Belongs to the glycosyl hydrolase 31 family
H1R14_RS17235	COG2017	converts alpha-aldose to the beta-anomer
H1R14_RS17240	COG2942	2-epimerase
H1R14_RS17245	COG3684	Belongs to the aldolase LacD family
H1R14_RS17250	COG2084	Dehydrogenase
H1R14_RS17255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS17260	COG1349	DNA-binding transcription factor activity
H1R14_RS17265	COG1011	Hydrolase
H1R14_RS17280	COG0456	acetyltransferase
H1R14_RS17285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1R14_RS17290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1R14_RS17300	COG2864	formate dehydrogenase
H1R14_RS17305	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS17325	COG3711	transcriptional antiterminator
H1R14_RS17325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS17330	COG1363	Peptidase, m42
H1R14_RS17335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS17335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS17340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS17380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1R14_RS17390	COG2258	MOSC domain
H1R14_RS17395	COG2205	protein histidine kinase activity
H1R14_RS17400	COG0745	RESPONSE REGULATOR receiver
H1R14_RS17405	COG3678	ATP-independent chaperone mediated protein folding
H1R14_RS17420	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1R14_RS17440	COG3152	Membrane
H1R14_RS17445	COG3691	Protein conserved in bacteria
H1R14_RS17450	COG0589	response to stress
H1R14_RS17455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1R14_RS17460	COG1494	fructose-1,6-bisphosphatase
H1R14_RS17470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H1R14_RS17485	COG1575	Belongs to the MenA family. Type 1 subfamily
H1R14_RS17500	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1R14_RS17505	COG1609	Transcriptional regulator
H1R14_RS17510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1R14_RS17520	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H1R14_RS17530	COG0626	cystathionine gamma-synthase activity
H1R14_RS17535	COG0460	homoserine dehydrogenase
H1R14_RS17535	COG0527	aspartate kinase activity
H1R14_RS17540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1R14_RS17550	COG0697	spore germination
H1R14_RS17555	COG3738	Protein conserved in bacteria
H1R14_RS17560	COG0371	Dehydrogenase
H1R14_RS17565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1R14_RS17570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS17570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1R14_RS17570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS17640	COG5001	Diguanylate cyclase
H1R14_RS17640	COG3300	MHYT domain
H1R14_RS17695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS17700	COG1882	Formate acetyltransferase
H1R14_RS17705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1R14_RS17710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS17715	COG2207	Transcriptional regulator
H1R14_RS17720	COG2194	sulfuric ester hydrolase activity
H1R14_RS17735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H1R14_RS17750	COG0583	DNA-binding transcription factor activity
H1R14_RS17760	COG1309	transcriptional regulator
H1R14_RS17775	COG4206	TonB-dependent receptor
H1R14_RS17805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H1R14_RS17810	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H1R14_RS17810	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H1R14_RS17845	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H1R14_RS17850	COG0250	Participates in transcription elongation, termination and antitermination
H1R14_RS17890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H1R14_RS17900	COG2104	thiamine diphosphate biosynthetic process
H1R14_RS17905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1R14_RS17940	COG3068	Protein conserved in bacteria
H1R14_RS17955	COG3678	ATP-independent chaperone mediated protein folding
H1R14_RS17960	COG4191	Histidine kinase
H1R14_RS17965	COG2204	response regulator
H1R14_RS17970	COG0151	Belongs to the GarS family
H1R14_RS18005	COG0456	acetyltransferase
H1R14_RS18015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1R14_RS18020	COG2224	Isocitrate lyase
H1R14_RS18035	COG1414	Transcriptional regulator
H1R14_RS18040	COG1410	methionine synthase
H1R14_RS18040	COG0646	methionine synthase
H1R14_RS18045	COG1283	sodium-dependent phosphate transmembrane transporter activity
H1R14_RS18055	COG1187	pseudouridine synthase activity
H1R14_RS18065	COG0527	aspartate kinase activity
H1R14_RS18090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1R14_RS18110	COG2814	Major facilitator Superfamily
H1R14_RS18110	COG0477	Major facilitator Superfamily
H1R14_RS18115	COG3833	ABC-type maltose transport systems, permease component
H1R14_RS18120	COG1175	transmembrane transport
H1R14_RS18125	COG2182	Extracellular solute-binding protein
H1R14_RS18130	COG3842	ATPase activity
H1R14_RS18165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H1R14_RS18175	COG0534	Mate efflux family protein
H1R14_RS18180	COG3237	CsbD-like
H1R14_RS18185	COG0735	belongs to the Fur family
H1R14_RS18195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1R14_RS18205	COG0604	alcohol dehydrogenase
H1R14_RS18210	COG0305	Participates in initiation and elongation during chromosome replication
H1R14_RS18215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1R14_RS18220	COG1448	Aminotransferase
H1R14_RS18230	COG3700	Belongs to the class B bacterial acid phosphatase family
H1R14_RS18235	COG0432	Pfam Uncharacterised protein family UPF0047
H1R14_RS18240	COG2315	Protein conserved in bacteria
H1R14_RS18245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1R14_RS18250	COG0629	single-stranded DNA binding
H1R14_RS18260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1R14_RS18265	COG2207	Transcriptional regulator
H1R14_RS18270	COG0789	Transcriptional regulator
H1R14_RS18275	COG2252	PERMEase
H1R14_RS18280	COG0025	NhaP-type Na H and K H
H1R14_RS18285	COG1357	PFAM Pentapeptide repeats (8 copies)
H1R14_RS18295	COG3162	membrane
H1R14_RS18300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1R14_RS18310	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
H1R14_RS18315	COG0437	4 iron, 4 sulfur cluster binding
H1R14_RS18320	COG3301	Polysulphide reductase, NrfD
H1R14_RS18325	COG1138	Cytochrome C-type biogenesis protein
H1R14_RS18330	COG3088	subunit of a heme lyase
H1R14_RS18335	COG4235	cytochrome complex assembly
H1R14_RS18340	COG1301	dicarboxylic acid transport
H1R14_RS18345	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H1R14_RS18355	COG1538	Outer membrane efflux protein
H1R14_RS18360	COG1289	transmembrane transporter activity
H1R14_RS18365	COG1566	PFAM secretion protein HlyD family protein
H1R14_RS18375	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H1R14_RS18380	COG1940	carbohydrate kinase activity
H1R14_RS18385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1R14_RS18390	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS18395	COG1129	ABC transporter
H1R14_RS18400	COG1879	ABC-type sugar transport system periplasmic component
H1R14_RS18405	COG1737	Transcriptional regulator
H1R14_RS18410	COG0698	ribose 5-phosphate isomerase
H1R14_RS18420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1R14_RS18425	COG0456	acetyltransferase
H1R14_RS18430	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
H1R14_RS18435	COG3454	Phosphonate metabolism
H1R14_RS18440	COG4778	phosphonate C-P lyase system protein PhnL
H1R14_RS18445	COG4107	phosphonate C-P lyase system protein PhnK
H1R14_RS18450	COG3627	carbon phosphorus lyase activity
H1R14_RS18455	COG3626	phosphonate metabolism
H1R14_RS18460	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H1R14_RS18465	COG3624	Phosphonate C-P lyase system protein PhnG
H1R14_RS18470	COG2188	Transcriptional regulator
H1R14_RS18480	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H1R14_RS18485	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H1R14_RS18490	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H1R14_RS18495	COG2824	Alkylphosphonate utilization operon protein PhnA
H1R14_RS18500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H1R14_RS18510	COG0477	Major facilitator Superfamily
H1R14_RS18520	COG0642	Histidine kinase
H1R14_RS18525	COG0745	RESPONSE REGULATOR receiver
H1R14_RS18530	COG2194	sulfuric ester hydrolase activity
H1R14_RS18535	COG0531	amino acid
H1R14_RS18540	COG2207	Transcriptional regulator
H1R14_RS18545	COG1982	Orn Lys Arg decarboxylase major
H1R14_RS18550	COG2169	Transcriptional regulator
H1R14_RS18555	COG1486	melibiose metabolic process
H1R14_RS18560	COG2211	Major facilitator Superfamily
H1R14_RS18565	COG3647	Membrane
H1R14_RS18570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1R14_RS18570	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1R14_RS18575	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H1R14_RS18580	COG4565	transcriptional regulatory protein
H1R14_RS18585	COG3290	protein histidine kinase activity
H1R14_RS18590	COG3592	Divergent 4Fe-4S mono-cluster
H1R14_RS18595	COG2388	GCN5-related N-acetyl-transferase
H1R14_RS18610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H1R14_RS18615	COG3104	oligopeptide transport
H1R14_RS18620	COG1982	Orn Lys Arg decarboxylase major
H1R14_RS18625	COG0531	amino acid
H1R14_RS18630	COG3710	Transcriptional regulator
H1R14_RS18640	COG1309	transcriptional regulator
H1R14_RS18645	COG4232	protein-disulfide reductase activity
H1R14_RS18655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H1R14_RS18660	COG1027	Aspartate ammonia-lyase
H1R14_RS18665	COG3030	protein affecting phage T7 exclusion by the F plasmid
H1R14_RS18670	COG0531	amino acid
H1R14_RS18695	COG1509	lysine 2,3-aminomutase activity
H1R14_RS18705	COG5510	response to toxic substance
H1R14_RS18710	COG5510	response to toxic substance
H1R14_RS18715	COG2076	Multidrug Resistance protein
H1R14_RS18720	COG3040	lipid binding
H1R14_RS18725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1R14_RS18740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1R14_RS18745	COG1053	succinate dehydrogenase
H1R14_RS18755	COG0531	amino acid
H1R14_RS18770	COG1511	domain protein
H1R14_RS18770	COG3264	Mechanosensitive ion channel
H1R14_RS18810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1R14_RS18815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1R14_RS18815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1R14_RS18820	COG0802	atpase or kinase
H1R14_RS18825	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1R14_RS18845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1R14_RS18850	COG0330	HflC and HflK could
H1R14_RS18855	COG0330	HflC and HflK could
H1R14_RS18860	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H1R14_RS18875	COG0557	exoribonuclease II activity
H1R14_RS18880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1R14_RS18885	COG3789	protein conserved in bacteria
H1R14_RS18890	COG1842	Phage shock protein A
H1R14_RS18900	COG3766	membrane
H1R14_RS18905	COG5463	Belongs to the UPF0441 family
H1R14_RS18910	COG0754	glutathionylspermidine amidase activity
H1R14_RS18915	COG1960	acyl-CoA dehydrogenase activity
H1R14_RS18925	COG3650	response to hydrogen peroxide
H1R14_RS18930	COG1073	alpha beta
H1R14_RS18945	COG3037	sugar-specific permease SgaT UlaA
H1R14_RS18950	COG3414	Phosphotransferase system galactitol-specific IIB component
H1R14_RS18990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H1R14_RS19000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1R14_RS19010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1R14_RS19020	COG4670	ketone body catabolic process
H1R14_RS19025	COG1024	Enoyl-CoA hydratase
H1R14_RS19035	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS19040	COG1309	transcriptional regulator
H1R14_RS19045	COG3061	Opacity-associated protein A
H1R14_RS19050	COG0545	Peptidyl-prolyl cis-trans isomerase
H1R14_RS19055	COG1113	amino acid transport
H1R14_RS19065	COG0697	spore germination
H1R14_RS19070	COG0702	epimerase
H1R14_RS19075	COG1733	regulation of RNA biosynthetic process
H1R14_RS19080	COG0737	Belongs to the 5'-nucleotidase family
H1R14_RS19085	COG1218	3'(2'),5'-bisphosphate nucleotidase
H1R14_RS19090	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H1R14_RS19100	COG1253	flavin adenine dinucleotide binding
H1R14_RS19110	COG0729	surface antigen
H1R14_RS19115	COG2911	Protein conserved in bacteria
H1R14_RS19120	COG2105	PFAM AIG2 family protein
H1R14_RS19125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1R14_RS19130	COG1879	ABC-type sugar transport system periplasmic component
H1R14_RS19135	COG1129	ABC transporter
H1R14_RS19140	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS19145	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1R14_RS19155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1R14_RS19165	COG0312	modulator of DNA gyrase
H1R14_RS19170	COG3783	Cytochrome b(562)
H1R14_RS19175	COG0602	queuosine metabolic process
H1R14_RS19180	COG1328	CTP reductase activity
H1R14_RS19185	COG0366	Alpha amylase catalytic
H1R14_RS19190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS19190	COG1263	PTS System
H1R14_RS19195	COG1609	Transcriptional regulator
H1R14_RS19205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1R14_RS19210	COG0251	oxidation-reduction process
H1R14_RS19230	COG0251	oxidation-reduction process
H1R14_RS19235	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS19240	COG1309	transcriptional regulator
H1R14_RS19245	COG2731	YhcH YjgK YiaL family protein
H1R14_RS19255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1R14_RS19260	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
H1R14_RS19265	COG0456	acetyltransferase
H1R14_RS19270	COG4269	membrane
H1R14_RS19280	COG2927	DNA polymerase III (CHI subunit)
H1R14_RS19290	COG0795	lipopolysaccharide-transporting ATPase activity
H1R14_RS19295	COG0795	lipopolysaccharide-transporting ATPase activity
H1R14_RS19300	COG0433	COG0433 Predicted ATPase
H1R14_RS19305	COG1064	alcohol dehydrogenase
H1R14_RS19315	COG0582	viral genome integration into host DNA
H1R14_RS19320	COG3039	Transposase
H1R14_RS19325	COG1120	ATPase activity
H1R14_RS19330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R14_RS19335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R14_RS19340	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H1R14_RS19345	COG4772	TonB-dependent receptor
H1R14_RS19350	COG3712	iron ion homeostasis
H1R14_RS19355	COG1595	DNA-templated transcription, initiation
H1R14_RS19395	COG3436	PFAM IS66 Orf2 family protein
H1R14_RS19435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H1R14_RS19475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H1R14_RS19490	COG2610	gluconate transmembrane transporter activity
H1R14_RS19500	COG0246	Mannitol dehydrogenase
H1R14_RS19505	COG2186	Transcriptional regulator
H1R14_RS19525	COG0583	DNA-binding transcription factor activity
H1R14_RS19530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1R14_RS19535	COG0700	Nucleoside recognition
H1R14_RS19540	COG3366	ferrous iron transmembrane transporter activity
H1R14_RS19550	COG0477	Major facilitator Superfamily
H1R14_RS19565	COG1924	4 iron, 4 sulfur cluster binding
H1R14_RS19570	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
H1R14_RS19575	COG2733	membrane
H1R14_RS19580	COG2814	Major facilitator Superfamily
H1R14_RS19600	COG0523	cobalamin synthesis protein
H1R14_RS19605	COG2879	small protein
H1R14_RS19610	COG1966	Carbon starvation protein
H1R14_RS19615	COG0840	transmembrane signaling receptor activity
H1R14_RS19620	COG2271	Major facilitator Superfamily
H1R14_RS19625	COG1802	Transcriptional regulator
H1R14_RS19630	COG1063	alcohol dehydrogenase
H1R14_RS19645	COG1484	DNA-dependent DNA replication
H1R14_RS19660	COG2966	Psort location CytoplasmicMembrane, score
H1R14_RS19665	COG2197	response regulator
H1R14_RS19670	COG2197	response regulator
H1R14_RS19675	COG4114	ferric iron reductase
H1R14_RS19705	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H1R14_RS19710	COG0456	acetyltransferase
H1R14_RS19715	COG1011	Hydrolase
H1R14_RS19725	COG2823	Periplasmic or secreted lipoprotein
H1R14_RS19735	COG4667	esterase of the alpha-beta hydrolase superfamily
H1R14_RS19740	COG0084	hydrolase, TatD family'
H1R14_RS19745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1R14_RS19750	COG1328	CTP reductase activity
H1R14_RS19785	COG3726	membrane protein affecting hemolysin expression
H1R14_RS19790	COG0560	Phosphoserine phosphatase
H1R14_RS19795	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H1R14_RS19800	COG3172	ATPase kinase involved in NAD metabolism
H1R14_RS19800	COG1056	cytidyltransferase-related domain
H1R14_RS19805	COG0488	(ABC) transporter
H1R14_RS19810	COG0741	lytic transglycosylase activity
H1R14_RS19830	COG2207	Transcriptional regulator
H1R14_RS19830	COG3708	Transcriptional regulator
H1R14_RS19835	COG3045	CreA protein
H1R14_RS19840	COG0745	RESPONSE REGULATOR receiver
H1R14_RS19845	COG2205	protein histidine kinase activity
H1R14_RS19850	COG4452	Inner membrane protein CreD
H1R14_RS19855	COG0745	RESPONSE REGULATOR receiver
H1R14_RS19865	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H1R14_RS19875	COG0527	aspartate kinase activity
H1R14_RS19875	COG0460	homoserine dehydrogenase
H1R14_RS19885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1R14_RS19900	COG1115	amino acid carrier protein
H1R14_RS19910	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1R14_RS19915	COG1584	GPR1 FUN34 yaaH family protein
H1R14_RS19920	COG4735	regulation of single-species biofilm formation
H1R14_RS19955	COG0583	DNA-binding transcription factor activity
H1R14_RS19985	COG0196	riboflavin kinase activity
H1R14_RS20000	COG1047	Peptidyl-prolyl cis-trans
H1R14_RS20020	COG0505	Belongs to the CarA family
H1R14_RS20025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H1R14_RS20075	COG0644	oxidoreductase
H1R14_RS20080	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1R14_RS20085	COG2271	Major facilitator Superfamily
H1R14_RS20100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1R14_RS20125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1R14_RS20130	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H1R14_RS20135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H1R14_RS20155	COG0564	pseudouridine synthase activity
H1R14_RS20165	COG0417	DNA replication proofreading
H1R14_RS20170	COG0235	Class ii aldolase
H1R14_RS20175	COG2160	L-arabinose isomerase activity
H1R14_RS20180	COG1069	ribulokinase activity
H1R14_RS20185	COG4977	sequence-specific DNA binding
H1R14_RS20190	COG0586	Pfam SNARE associated Golgi protein
H1R14_RS20195	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
H1R14_RS20200	COG1178	ABC-type Fe3 transport system permease component
H1R14_RS20205	COG4143	(ABC) transporter
H1R14_RS20210	COG4533	DNA binding
H1R14_RS20220	COG2814	Major facilitator Superfamily
H1R14_RS20235	COG0473	3-isopropylmalate dehydrogenase activity
H1R14_RS20250	COG0583	DNA-binding transcription factor activity
H1R14_RS20260	COG0028	Belongs to the TPP enzyme family
H1R14_RS20265	COG0440	acetolactate synthase activity
H1R14_RS20275	COG1609	Transcriptional regulator
H1R14_RS20280	COG2001	Belongs to the MraZ family
H1R14_RS20290	COG3116	cell division
H1R14_RS20295	COG0768	penicillin binding
H1R14_RS20300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1R14_RS20305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1R14_RS20315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H1R14_RS20320	COG0772	Belongs to the SEDS family
H1R14_RS20335	COG1181	Belongs to the D-alanine--D-alanine ligase family
H1R14_RS20340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1R14_RS20345	COG0849	cell division
H1R14_RS20350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1R14_RS20370	COG0494	nUDIX hydrolase
H1R14_RS20385	COG0237	dephospho-CoA kinase activity
H1R14_RS20400	COG1459	type II secretion system
H1R14_RS20405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1R14_RS20410	COG4969	Belongs to the N-Me-Phe pilin family
H1R14_RS20415	COG0157	Belongs to the NadC ModD family
H1R14_RS20420	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1R14_RS20425	COG3725	Membrane protein required for beta-lactamase induction
H1R14_RS20430	COG1113	amino acid transport
H1R14_RS20435	COG2186	Transcriptional regulator
H1R14_RS20440	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H1R14_RS20445	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1R14_RS20450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1R14_RS20455	COG3064	Membrane
H1R14_RS20460	COG1049	propionate catabolic process, 2-methylcitrate cycle
H1R14_RS20485	COG2132	Multicopper oxidase
H1R14_RS20490	COG4993	Dehydrogenase
H1R14_RS20495	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H1R14_RS20500	COG0288	reversible hydration of carbon dioxide
H1R14_RS20505	COG1131	(ABC) transporter
H1R14_RS20510	COG0842	Transport permease protein
H1R14_RS20515	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS20520	COG0726	polysaccharide deacetylase
H1R14_RS20530	COG5464	transposase or invertase
H1R14_RS20545	COG3539	Fimbrial protein
H1R14_RS20550	COG3539	Fimbrial protein
H1R14_RS20555	COG3539	Fimbrial protein
H1R14_RS20560	COG3539	Fimbrial protein
H1R14_RS20565	COG3188	usher protein
H1R14_RS20570	COG3121	Chaperone
H1R14_RS20575	COG3539	Fimbrial protein
H1R14_RS20580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1R14_RS20585	COG0617	tRNA 3'-terminal CCA addition
H1R14_RS20595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1R14_RS20605	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H1R14_RS20610	COG1643	Atp-dependent helicase
H1R14_RS20615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1R14_RS20620	COG4774	siderophore transport
H1R14_RS20625	COG1120	ATPase activity
H1R14_RS20630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1R14_RS20635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R14_RS20660	COG2860	membrane
H1R14_RS20665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1R14_RS20680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1R14_RS20685	COG3835	regulator
H1R14_RS20695	COG1408	metallophosphoesterase
H1R14_RS20710	COG0024	Methionine aminopeptidase
H1R14_RS20735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H1R14_RS20740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1R14_RS20745	COG0575	Belongs to the CDS family
H1R14_RS20750	COG0750	zinc metalloprotease
H1R14_RS20760	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H1R14_RS20765	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1R14_RS20790	COG0587	DNA-directed DNA polymerase activity
H1R14_RS20805	COG0346	lactoylglutathione lyase activity
H1R14_RS20810	COG0037	tRNA processing
H1R14_RS20815	COG4568	rho-dependent transcription termination
H1R14_RS20825	COG4681	YaeQ
H1R14_RS20830	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H1R14_RS20835	COG3015	lipoprotein NlpE involved in copper resistance
H1R14_RS20840	COG0791	NLP P60 protein
H1R14_RS20850	COG1720	tRNA m6t6A37 methyltransferase activity
H1R14_RS20860	COG1464	Belongs to the NlpA lipoprotein family
H1R14_RS20865	COG2011	ABC-type metal ion transport system permease component
H1R14_RS20870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1R14_RS20875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H1R14_RS20910	COG0656	L-ascorbic acid biosynthetic process
H1R14_RS20915	COG0583	DNA-binding transcription factor activity
H1R14_RS20930	COG1388	LysM domain
H1R14_RS20930	COG0741	lytic transglycosylase activity
H1R14_RS20940	COG2226	methyltransferase
H1R14_RS20950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1R14_RS20970	COG4104	PAAR repeat-containing protein
H1R14_RS20975	COG3157	Type VI secretion system effector, Hcp
H1R14_RS20995	COG3209	COG3209 Rhs family protein
H1R14_RS21005	COG5433	transposase activity
H1R14_RS21010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1R14_RS21020	COG1960	acyl-CoA dehydrogenase activity
H1R14_RS21030	COG0121	glutamine amidotransferase
H1R14_RS21035	COG3034	peptidoglycan biosynthetic process
H1R14_RS21040	COG3041	Addiction module toxin RelE StbE family
H1R14_RS21045	COG3077	Addiction module antitoxin, RelB DinJ family
H1R14_RS21050	COG0791	NLP P60 protein
H1R14_RS21055	COG1943	Transposase
H1R14_RS21075	COG1987	bacterial-type flagellum assembly
H1R14_RS21100	COG1677	Flagellar hook-basal body complex protein FliE
H1R14_RS21110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1R14_RS21130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H1R14_RS21160	COG1815	bacterial-type flagellum-dependent cell motility
H1R14_RS21165	COG1558	bacterial-type flagellum-dependent cell motility
H1R14_RS21175	COG1749	Flagellar hook protein flgE
H1R14_RS21180	COG4787	bacterial-type flagellum-dependent cell motility
H1R14_RS21185	COG4786	Flagellar basal body rod
H1R14_RS21210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H1R14_RS21225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H1R14_RS21230	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H1R14_RS21255	COG1191	sigma factor activity
H1R14_RS21260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H1R14_RS21275	COG2161	toxin-antitoxin pair type II binding
H1R14_RS21285	COG0454	-acetyltransferase
H1R14_RS21300	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1R14_RS21320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1R14_RS21340	COG0583	DNA-binding transcription factor activity
H1R14_RS21345	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H1R14_RS21350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1R14_RS21355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H1R14_RS21360	COG2080	2 iron, 2 sulfur cluster binding
H1R14_RS21365	COG3477	response to acidic pH
H1R14_RS21370	COG0727	PFAM Uncharacterised protein family (UPF0153)
H1R14_RS21375	COG3121	Chaperone
H1R14_RS21385	COG3188	usher protein
H1R14_RS21430	COG2207	Transcriptional regulator
H1R14_RS21430	COG3708	Transcriptional regulator
H1R14_RS21440	COG3059	membrane
H1R14_RS21450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1R14_RS21455	COG2207	Transcriptional regulator
H1R14_RS21460	COG0247	lactate metabolic process
H1R14_RS21465	COG1139	Iron-sulfur cluster binding protein
H1R14_RS21470	COG1556	Lactate utilization protein
H1R14_RS21495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1R14_RS21510	COG0583	DNA-binding transcription factor activity
H1R14_RS21520	COG0666	response to abiotic stimulus
H1R14_RS21530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1R14_RS21535	COG1304	FMN binding
H1R14_RS21545	COG0549	Belongs to the carbamate kinase family
H1R14_RS21550	COG0402	S-adenosylhomocysteine deaminase activity
H1R14_RS21555	COG1064	alcohol dehydrogenase
H1R14_RS21570	COG1280	lysine exporter protein (LysE YggA)
H1R14_RS21580	COG3829	transcription factor binding
H1R14_RS21585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H1R14_RS21590	COG0372	Belongs to the citrate synthase family
H1R14_RS21595	COG2079	MmgE PrpD family protein
H1R14_RS21600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1R14_RS21605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1R14_RS21610	COG0402	S-adenosylhomocysteine deaminase activity
H1R14_RS21615	COG0583	DNA-binding transcription factor activity
H1R14_RS21620	COG0288	reversible hydration of carbon dioxide
H1R14_RS21630	COG2807	transmembrane transport
H1R14_RS21635	COG0110	maltose O-acetyltransferase activity
H1R14_RS21640	COG2223	nitrite transmembrane transporter activity
H1R14_RS21645	COG3250	beta-galactosidase activity
H1R14_RS21650	COG1609	Transcriptional regulator
H1R14_RS21655	COG1414	Transcriptional regulator
H1R14_RS21675	COG3971	2-oxopent-4-enoate hydratase activity
H1R14_RS21690	COG2814	Major facilitator Superfamily
H1R14_RS21695	COG3122	Protein conserved in bacteria
H1R14_RS21725	COG1215	transferase activity, transferring glycosyl groups
H1R14_RS21730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H1R14_RS21735	COG4521	taurine ABC transporter
H1R14_RS21745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1R14_RS21750	COG2175	clavaminate synthase activity
H1R14_RS21755	COG0113	porphobilinogen synthase activity
H1R14_RS21760	COG3468	outer membrane autotransporter barrel domain protein
H1R14_RS21765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1R14_RS21770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1R14_RS21775	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1R14_RS21795	COG1181	Belongs to the D-alanine--D-alanine ligase family
H1R14_RS21810	COG1785	Belongs to the alkaline phosphatase family
H1R14_RS21820	COG3706	GGDEF domain
H1R14_RS21825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H1R14_RS21845	COG4126	flavin adenine dinucleotide binding
H1R14_RS21870	COG1940	carbohydrate kinase activity
H1R14_RS21875	COG2814	Major facilitator Superfamily
H1R14_RS21880	COG0419	ATPase involved in DNA repair
H1R14_RS21885	COG0420	3'-5' exonuclease activity
H1R14_RS21890	COG0745	RESPONSE REGULATOR receiver
H1R14_RS21895	COG5002	protein histidine kinase activity
H1R14_RS21900	COG1114	Component of the transport system for branched-chain amino acids
H1R14_RS21905	COG1113	amino acid transport
H1R14_RS21910	COG0366	Alpha amylase catalytic
H1R14_RS21930	COG1862	Preprotein translocase
H1R14_RS21935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1R14_RS21940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1R14_RS21945	COG1403	HNH endonuclease
H1R14_RS21950	COG3248	Nucleoside-binding outer membrane protein
H1R14_RS21955	COG4238	major outer membrane lipoprotein
H1R14_RS21965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1R14_RS21965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1R14_RS21980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1R14_RS21985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1R14_RS21990	COG0667	Aldo Keto reductase
H1R14_RS22000	COG0142	geranyltranstransferase activity
H1R14_RS22015	COG0693	protein deglycase activity
H1R14_RS22020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H1R14_RS22030	COG2814	Major facilitator Superfamily
H1R14_RS22040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1R14_RS22045	COG1845	cytochrome c oxidase, subunit III
H1R14_RS22050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1R14_RS22055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1R14_RS22060	COG2223	nitrite transmembrane transporter activity
H1R14_RS22065	COG3056	Lipoprotein
H1R14_RS22070	COG0271	Belongs to the BolA IbaG family
H1R14_RS22090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H1R14_RS22095	COG0776	regulation of translation
H1R14_RS22100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1R14_RS22105	COG1555	photosystem II stabilization
H1R14_RS22110	COG0824	Thioesterase
H1R14_RS22120	COG4533	DNA binding
H1R14_RS22130	COG1522	sequence-specific DNA binding
H1R14_RS22135	COG1132	(ABC) transporter
H1R14_RS22140	COG1132	(ABC) transporter
H1R14_RS22145	COG0347	Belongs to the P(II) protein family
H1R14_RS22150	COG0004	ammonium transporteR
H1R14_RS22155	COG1946	Acyl-CoA thioesterase
H1R14_RS22160	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H1R14_RS22165	COG3695	enzyme binding
H1R14_RS22175	COG5507	3-demethylubiquinone-9 3-methyltransferase
H1R14_RS22180	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1R14_RS22190	COG0110	maltose O-acetyltransferase activity
H1R14_RS22205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1R14_RS22210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS22215	COG1309	transcriptional regulator
H1R14_RS22220	COG1196	nuclear chromosome segregation
H1R14_RS22220	COG3264	Mechanosensitive ion channel
H1R14_RS22230	COG3923	Primosomal replication protein n
H1R14_RS22235	COG2832	Protein of unknown function (DUF454)
H1R14_RS22245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1R14_RS22280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1R14_RS22285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1R14_RS22285	COG4651	solute:proton antiporter activity
H1R14_RS22290	COG2223	nitrite transmembrane transporter activity
H1R14_RS22295	COG0737	Belongs to the 5'-nucleotidase family
H1R14_RS22300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1R14_RS22305	COG3735	TraB family
H1R14_RS22310	COG3093	addiction module antidote protein HigA
H1R14_RS22315	COG2217	Heavy metal translocating P-type atpase
H1R14_RS22320	COG2066	Belongs to the glutaminase family
H1R14_RS22325	COG0531	amino acid
H1R14_RS22330	COG0789	Transcriptional regulator
H1R14_RS22335	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1R14_RS22340	COG0330	HflC and HflK could
H1R14_RS22345	COG4619	ABC transporter
H1R14_RS22350	COG0390	transport system, permease component
H1R14_RS22355	COG3118	belongs to the thioredoxin family
H1R14_RS22360	COG0300	oxidoreductase activity
H1R14_RS22365	COG2755	lipolytic protein G-D-S-L family
H1R14_RS22370	COG4181	ATPase activity
H1R14_RS22375	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1R14_RS22380	COG3209	COG3209 Rhs family protein
H1R14_RS22390	COG3209	COG3209 Rhs family protein
H1R14_RS22415	COG0583	DNA-binding transcription factor activity
H1R14_RS22425	COG1414	Transcriptional regulator
H1R14_RS22430	COG3960	tartronate-semialdehyde synthase activity
H1R14_RS22435	COG3622	Belongs to the hyi family
H1R14_RS22440	COG2084	Dehydrogenase
H1R14_RS22445	COG1953	Uracil, thiamine, allantoin
H1R14_RS22455	COG2233	PERMEase
H1R14_RS22460	COG1929	Belongs to the glycerate kinase type-1 family
H1R14_RS22465	COG3257	ureidoglycine aminohydrolase activity
H1R14_RS22470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1R14_RS22475	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H1R14_RS22480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1R14_RS22485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1R14_RS22495	COG0549	Belongs to the carbamate kinase family
H1R14_RS22500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1R14_RS22505	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H1R14_RS22515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1R14_RS22525	COG1988	membrane-bound metal-dependent
H1R14_RS22530	COG2501	S4 domain
H1R14_RS22540	COG3539	Fimbrial protein
H1R14_RS22545	COG3121	Chaperone
H1R14_RS22550	COG3188	usher protein
H1R14_RS22555	COG3539	Fimbrial protein
H1R14_RS22560	COG3539	Fimbrial protein
H1R14_RS22565	COG2197	response regulator
H1R14_RS22575	COG2207	Transcriptional regulator
H1R14_RS22585	COG4783	chaperone-mediated protein folding
H1R14_RS22590	COG1215	transferase activity, transferring glycosyl groups
H1R14_RS22595	COG5002	protein histidine kinase activity
H1R14_RS22600	COG0745	RESPONSE REGULATOR receiver
H1R14_RS22605	COG1538	Outer membrane efflux protein
H1R14_RS22610	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS22615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS22620	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1R14_RS22625	COG1113	amino acid transport
H1R14_RS22630	COG0668	transmembrane transport
H1R14_RS22635	COG0778	Nitroreductase
H1R14_RS22640	COG2315	Protein conserved in bacteria
H1R14_RS22665	COG2977	Belongs to the P-Pant transferase superfamily
H1R14_RS22670	COG4771	TonB-dependent receptor
H1R14_RS22675	COG2382	esterase
H1R14_RS22680	COG3251	PFAM MbtH domain protein
H1R14_RS22685	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1R14_RS22685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1R14_RS22690	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H1R14_RS22695	COG1120	ATPase activity
H1R14_RS22700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R14_RS22705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R14_RS22715	COG4592	Periplasmic binding protein
H1R14_RS22720	COG1169	isochorismate synthase
H1R14_RS22725	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1R14_RS22730	COG1535	isochorismatase
H1R14_RS22730	COG3433	isochorismatase activity
H1R14_RS22735	COG1028	Short-chain dehydrogenase reductase Sdr
H1R14_RS22740	COG2050	protein possibly involved in aromatic compounds catabolism
H1R14_RS22745	COG1966	Carbon starvation protein
H1R14_RS22750	COG2879	small protein
H1R14_RS22755	COG0371	Dehydrogenase
H1R14_RS22760	COG0436	Aminotransferase
H1R14_RS22765	COG1475	DNA binding
H1R14_RS22770	COG3969	phosphoadenosine phosphosulfate
H1R14_RS22775	COG0583	DNA-binding transcription factor activity
H1R14_RS22780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1R14_RS22785	COG0450	alkyl hydroperoxide reductase
H1R14_RS22790	COG3634	alkyl hydroperoxide reductase activity
H1R14_RS22795	COG0589	response to stress
H1R14_RS22800	COG1063	alcohol dehydrogenase
H1R14_RS22805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1R14_RS22810	COG3719	Belongs to the RNase T2 family
H1R14_RS22815	COG0471	metal ion transport
H1R14_RS22830	COG3051	citrate lyase alpha subunit
H1R14_RS22835	COG2301	Belongs to the HpcH HpaI aldolase family
H1R14_RS22845	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
H1R14_RS22850	COG3290	protein histidine kinase activity
H1R14_RS22855	COG4565	transcriptional regulatory protein
H1R14_RS22860	COG3069	C4-dicarboxylate transmembrane transporter activity
H1R14_RS22885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1R14_RS22895	COG0583	DNA-binding transcription factor activity
H1R14_RS22910	COG1686	Belongs to the peptidase S11 family
H1R14_RS22915	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1R14_RS22920	COG0772	Belongs to the SEDS family
H1R14_RS22925	COG0768	penicillin binding
H1R14_RS22935	COG0799	negative regulation of ribosome biogenesis
H1R14_RS22940	COG0406	alpha-ribazole phosphatase activity
H1R14_RS22950	COG1466	dna polymerase III delta subunit
H1R14_RS22965	COG2888	peptidyl-tyrosine sulfation
H1R14_RS22970	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H1R14_RS22980	COG2214	Heat shock protein DnaJ domain protein
H1R14_RS22985	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H1R14_RS22995	COG2214	Heat shock protein DnaJ domain protein
H1R14_RS23000	COG0443	Heat shock 70 kDa protein
H1R14_RS23010	COG1126	abc transporter atp-binding protein
H1R14_RS23015	COG0765	amino acid transport
H1R14_RS23020	COG0765	amino acid transport
H1R14_RS23025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS23030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H1R14_RS23035	COG4535	Mg2 and Co2 transporter CorC
H1R14_RS23045	COG1702	phosphate starvation-inducible protein PhoH
H1R14_RS23055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1R14_RS23095	COG0367	asparagine synthase
H1R14_RS23100	COG0647	UMP catabolic process
H1R14_RS23105	COG1846	Transcriptional regulator
H1R14_RS23105	COG1940	carbohydrate kinase activity
H1R14_RS23110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1R14_RS23120	COG1263	PTS System
H1R14_RS23120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R14_RS23120	COG2190	(PTS) system
H1R14_RS23140	COG0735	belongs to the Fur family
H1R14_RS23150	COG0716	FMN binding
H1R14_RS23160	COG0596	Alpha beta hydrolase
H1R14_RS23165	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H1R14_RS23170	COG0033	Phosphoglucomutase
H1R14_RS23190	COG0531	amino acid
H1R14_RS23195	COG1982	Orn Lys Arg decarboxylase major
H1R14_RS23205	COG0745	RESPONSE REGULATOR receiver
H1R14_RS23210	COG2205	protein histidine kinase activity
H1R14_RS23240	COG3209	COG3209 Rhs family protein
H1R14_RS23275	COG2826	transposase and inactivated derivatives, IS30 family
H1R14_RS23285	COG3272	Protein of unknown function (DUF1722)
H1R14_RS23290	COG0415	Belongs to the DNA photolyase family
H1R14_RS23295	COG3104	oligopeptide transport
H1R14_RS23300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1R14_RS23305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H1R14_RS23310	COG1984	allophanate hydrolase subunit 2
H1R14_RS23325	COG3180	Ammonia monooxygenase
H1R14_RS23330	COG3539	Fimbrial protein
H1R14_RS23335	COG3121	Chaperone
H1R14_RS23340	COG3188	usher protein
H1R14_RS23345	COG3539	Fimbrial protein
H1R14_RS23350	COG0372	Belongs to the citrate synthase family
H1R14_RS23360	COG2009	succinate dehydrogenase
H1R14_RS23365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1R14_RS23370	COG1053	succinate dehydrogenase
H1R14_RS23375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1R14_RS23380	COG0567	Dehydrogenase, E1 component
H1R14_RS23385	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1R14_RS23395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1R14_RS23400	COG2188	Transcriptional regulator
H1R14_RS23405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS23405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R14_RS23405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R14_RS23410	COG0383	alpha-mannosidase activity
H1R14_RS23420	COG1271	oxidase subunit
H1R14_RS23425	COG1294	oxidase, subunit
H1R14_RS23430	COG4890	Cyd operon protein YbgT
H1R14_RS23435	COG3790	cyd operon protein YbgE
H1R14_RS23440	COG0824	Thioesterase
H1R14_RS23445	COG0811	peptide transport
H1R14_RS23450	COG0848	biopolymer transport protein
H1R14_RS23455	COG3064	Membrane
H1R14_RS23465	COG2885	chlorophyll binding
H1R14_RS23470	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H1R14_RS23520	COG3201	nicotinamide mononucleotide transporter
H1R14_RS23525	COG1230	cation diffusion facilitator family transporter
H1R14_RS23535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1R14_RS23545	COG2017	converts alpha-aldose to the beta-anomer
H1R14_RS23555	COG1085	galactose-1-phosphate uridylyltransferase
H1R14_RS23560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1R14_RS23565	COG1119	ATPase activity
H1R14_RS23570	COG2005	Transcriptional regulator
H1R14_RS23570	COG3585	molybdate ion transport
H1R14_RS23580	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1R14_RS23585	COG4149	molybdate abc transporter
H1R14_RS23590	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1R14_RS23595	COG0561	phosphatase activity
H1R14_RS23605	COG0583	DNA-binding transcription factor activity
H1R14_RS23610	COG2828	Protein conserved in bacteria
H1R14_RS23615	COG0471	metal ion transport
H1R14_RS23620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1R14_RS23625	COG4677	pectinesterase activity
H1R14_RS23630	COG1881	PFAM PEBP family protein
H1R14_RS23635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1R14_RS23650	COG2226	methyltransferase
H1R14_RS23655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H1R14_RS23665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H1R14_RS23675	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1R14_RS23685	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H1R14_RS23690	COG0314	molybdopterin synthase activity
H1R14_RS23695	COG0670	Belongs to the BI1 family
H1R14_RS23700	COG0670	Belongs to the BI1 family
H1R14_RS23705	COG0392	lysyltransferase activity
H1R14_RS23710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1R14_RS23715	COG3568	Endonuclease Exonuclease Phosphatase
H1R14_RS23725	COG0842	Transport permease protein
H1R14_RS23730	COG0842	Transport permease protein
H1R14_RS23735	COG1131	(ABC) transporter
H1R14_RS23745	COG1309	transcriptional regulator
H1R14_RS23750	COG0513	Belongs to the DEAD box helicase family
H1R14_RS23755	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
H1R14_RS23760	COG1199	ATP-dependent helicase activity
H1R14_RS23765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1R14_RS23770	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H1R14_RS23780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1R14_RS23790	COG4774	siderophore transport
H1R14_RS23805	COG0668	transmembrane transport
H1R14_RS23810	COG1126	abc transporter atp-binding protein
H1R14_RS23815	COG0765	amino acid transport
H1R14_RS23820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS23830	COG5006	permease, DMT superfamily
H1R14_RS23840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1R14_RS23845	COG2194	sulfuric ester hydrolase activity
H1R14_RS23855	COG1321	iron dependent repressor
H1R14_RS23860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1R14_RS23865	COG1376	ErfK ybiS ycfS ynhG family protein
H1R14_RS23870	COG0488	(ABC) transporter
H1R14_RS23880	COG0561	phosphatase activity
H1R14_RS23885	COG1882	Formate acetyltransferase
H1R14_RS23890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1R14_RS23895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1R14_RS23900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1R14_RS23905	COG0303	'Molybdopterin
H1R14_RS23910	COG1446	asparaginase
H1R14_RS23915	COG4172	Belongs to the ABC transporter superfamily
H1R14_RS23920	COG0747	negative chemotaxis
H1R14_RS23930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1R14_RS23940	COG2199	diguanylate cyclase activity
H1R14_RS23955	COG2133	pyrroloquinoline quinone binding
H1R14_RS23960	COG0625	glutathione transferase activity
H1R14_RS23965	COG1686	Belongs to the peptidase S11 family
H1R14_RS23970	COG1349	DNA-binding transcription factor activity
H1R14_RS23975	COG0671	phosphoesterase, PA-phosphatase related
H1R14_RS23980	COG2814	Major facilitator Superfamily
H1R14_RS23990	COG0561	phosphatase activity
H1R14_RS23995	COG0738	Major facilitator superfamily
H1R14_RS24000	COG3226	Transcriptional regulator
H1R14_RS24015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1R14_RS24025	COG0778	Nitroreductase
H1R14_RS24030	COG2826	transposase and inactivated derivatives, IS30 family
H1R14_RS24045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H1R14_RS24050	COG3842	ATPase activity
H1R14_RS24055	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1R14_RS24060	COG1177	transmembrane transport
H1R14_RS24075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS24080	COG4160	amino acid transport
H1R14_RS24085	COG4215	(ABC) transporter
H1R14_RS24090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R14_RS24095	COG1126	abc transporter atp-binding protein
H1R14_RS24110	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1R14_RS24115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1R14_RS24120	COG0702	epimerase
H1R14_RS24125	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H1R14_RS24130	COG0028	Belongs to the TPP enzyme family
H1R14_RS24135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1R14_RS24145	COG2431	L-lysine efflux transmembrane transporter activity
H1R14_RS24155	COG3593	DNA synthesis involved in DNA repair
H1R14_RS24160	COG2990	Protein conserved in bacteria
H1R14_RS24165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1R14_RS24170	COG0577	efflux transmembrane transporter activity
H1R14_RS24170	COG1136	(ABC) transporter
H1R14_RS24175	COG1278	Cold shock