locus-tag	class	description
E1A98_RS00010	COG0527	aspartate kinase activity
E1A98_RS00010	COG0460	homoserine dehydrogenase
E1A98_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E1A98_RS00035	COG1115	amino acid carrier protein
E1A98_RS00045	COG0521	Mo-molybdopterin cofactor biosynthetic process
E1A98_RS00050	COG1584	GPR1 FUN34 yaaH family protein
E1A98_RS00055	COG4735	regulation of single-species biofilm formation
E1A98_RS00075	COG3385	transposase activity
E1A98_RS00085	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E1A98_RS00090	COG0583	DNA-binding transcription factor activity
E1A98_RS00110	COG0196	riboflavin kinase activity
E1A98_RS00125	COG1047	Peptidyl-prolyl cis-trans
E1A98_RS00145	COG0505	Belongs to the CarA family
E1A98_RS00150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E1A98_RS00200	COG0644	oxidoreductase
E1A98_RS00205	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E1A98_RS00210	COG2271	Major facilitator Superfamily
E1A98_RS00225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
E1A98_RS00250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E1A98_RS00255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E1A98_RS00260	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
E1A98_RS00265	COG1357	PFAM Pentapeptide repeats (8 copies)
E1A98_RS00280	COG0564	pseudouridine synthase activity
E1A98_RS00290	COG0417	DNA replication proofreading
E1A98_RS00295	COG0235	Class ii aldolase
E1A98_RS00300	COG4977	sequence-specific DNA binding
E1A98_RS00305	COG0586	Pfam SNARE associated Golgi protein
E1A98_RS00310	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
E1A98_RS00315	COG1178	ABC-type Fe3 transport system permease component
E1A98_RS00320	COG4143	(ABC) transporter
E1A98_RS00325	COG4533	DNA binding
E1A98_RS00335	COG2814	Major facilitator Superfamily
E1A98_RS00350	COG0473	3-isopropylmalate dehydrogenase activity
E1A98_RS00365	COG0583	DNA-binding transcription factor activity
E1A98_RS00375	COG0028	Belongs to the TPP enzyme family
E1A98_RS00380	COG0440	acetolactate synthase activity
E1A98_RS00390	COG1609	Transcriptional regulator
E1A98_RS00395	COG2001	Belongs to the MraZ family
E1A98_RS00405	COG3116	cell division
E1A98_RS00410	COG0768	penicillin binding
E1A98_RS00415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E1A98_RS00420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E1A98_RS00430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E1A98_RS00435	COG0772	Belongs to the SEDS family
E1A98_RS00450	COG1181	Belongs to the D-alanine--D-alanine ligase family
E1A98_RS00455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E1A98_RS00460	COG0849	cell division
E1A98_RS00465	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E1A98_RS00485	COG0494	nUDIX hydrolase
E1A98_RS00500	COG0237	dephospho-CoA kinase activity
E1A98_RS00510	COG1459	type II secretion system
E1A98_RS00515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E1A98_RS00520	COG4969	Belongs to the N-Me-Phe pilin family
E1A98_RS00525	COG0157	Belongs to the NadC ModD family
E1A98_RS00530	COG3023	N-Acetylmuramoyl-L-alanine amidase
E1A98_RS00535	COG3725	Membrane protein required for beta-lactamase induction
E1A98_RS00540	COG1113	amino acid transport
E1A98_RS00545	COG2186	Transcriptional regulator
E1A98_RS00550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E1A98_RS00555	COG0508	dehydrogenase complex catalyzes the overall conversion of
E1A98_RS00560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E1A98_RS00565	COG3064	Membrane
E1A98_RS00570	COG1049	propionate catabolic process, 2-methylcitrate cycle
E1A98_RS00595	COG2132	Multicopper oxidase
E1A98_RS00600	COG4993	Dehydrogenase
E1A98_RS00605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E1A98_RS00610	COG0288	reversible hydration of carbon dioxide
E1A98_RS00615	COG1131	(ABC) transporter
E1A98_RS00620	COG0842	Transport permease protein
E1A98_RS00625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS00630	COG0726	polysaccharide deacetylase
E1A98_RS00640	COG5464	transposase or invertase
E1A98_RS00655	COG3539	Fimbrial protein
E1A98_RS00660	COG3539	Fimbrial protein
E1A98_RS00665	COG3539	Fimbrial protein
E1A98_RS00670	COG3539	Fimbrial protein
E1A98_RS00675	COG3188	usher protein
E1A98_RS00680	COG3121	Chaperone
E1A98_RS00685	COG3539	Fimbrial protein
E1A98_RS00690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E1A98_RS00695	COG0617	tRNA 3'-terminal CCA addition
E1A98_RS00705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E1A98_RS00715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E1A98_RS00720	COG1643	Atp-dependent helicase
E1A98_RS00725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E1A98_RS00730	COG4774	siderophore transport
E1A98_RS00735	COG1120	ATPase activity
E1A98_RS00740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A98_RS00745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A98_RS00770	COG2860	membrane
E1A98_RS00775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A98_RS00790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E1A98_RS00795	COG3835	regulator
E1A98_RS00810	COG1408	metallophosphoesterase
E1A98_RS00825	COG0024	Methionine aminopeptidase
E1A98_RS00850	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E1A98_RS00855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E1A98_RS00860	COG0575	Belongs to the CDS family
E1A98_RS00865	COG0750	zinc metalloprotease
E1A98_RS00875	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
E1A98_RS00880	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E1A98_RS00905	COG0587	DNA-directed DNA polymerase activity
E1A98_RS00920	COG0346	lactoylglutathione lyase activity
E1A98_RS00925	COG0037	tRNA processing
E1A98_RS00930	COG4568	rho-dependent transcription termination
E1A98_RS00940	COG4681	YaeQ
E1A98_RS00945	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E1A98_RS00950	COG3015	lipoprotein NlpE involved in copper resistance
E1A98_RS00955	COG0791	NLP P60 protein
E1A98_RS00965	COG1720	tRNA m6t6A37 methyltransferase activity
E1A98_RS00975	COG1464	Belongs to the NlpA lipoprotein family
E1A98_RS00980	COG2011	ABC-type metal ion transport system permease component
E1A98_RS00985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
E1A98_RS00990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E1A98_RS01025	COG0656	L-ascorbic acid biosynthetic process
E1A98_RS01030	COG0583	DNA-binding transcription factor activity
E1A98_RS01040	COG2226	methyltransferase
E1A98_RS01045	COG0741	lytic transglycosylase activity
E1A98_RS01045	COG1388	LysM domain
E1A98_RS01050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A98_RS01055	COG2226	methyltransferase
E1A98_RS01065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E1A98_RS01095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E1A98_RS01105	COG1960	acyl-CoA dehydrogenase activity
E1A98_RS01115	COG0121	glutamine amidotransferase
E1A98_RS01120	COG3034	peptidoglycan biosynthetic process
E1A98_RS01125	COG3041	Addiction module toxin RelE StbE family
E1A98_RS01130	COG3077	Addiction module antitoxin, RelB DinJ family
E1A98_RS01135	COG0791	NLP P60 protein
E1A98_RS01140	COG1943	Transposase
E1A98_RS01160	COG2161	toxin-antitoxin pair type II binding
E1A98_RS01170	COG0454	-acetyltransferase
E1A98_RS01175	COG1690	Belongs to the RtcB family
E1A98_RS01180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E1A98_RS01185	COG2195	Cleaves the N-terminal amino acid of tripeptides
E1A98_RS01205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E1A98_RS01245	COG2003	Belongs to the UPF0758 family
E1A98_RS01265	COG2378	regulation of single-species biofilm formation
E1A98_RS01285	COG3596	GTP binding
E1A98_RS01290	COG0583	DNA-binding transcription factor activity
E1A98_RS01315	COG3039	Transposase
E1A98_RS01320	COG0833	amino acid
E1A98_RS01325	COG2040	homocysteine
E1A98_RS01330	COG3842	ATPase activity
E1A98_RS01350	COG2963	transposase activity
E1A98_RS01360	COG2801	Transposase and inactivated derivatives
E1A98_RS01360	COG3415	Transposase
E1A98_RS01365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E1A98_RS01370	COG0129	dihydroxy-acid dehydratase activity
E1A98_RS01375	COG2211	Major facilitator Superfamily
E1A98_RS01380	COG3507	Belongs to the glycosyl hydrolase 43 family
E1A98_RS01385	COG1414	Transcriptional regulator
E1A98_RS01390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E1A98_RS01405	COG1061	Type III restriction enzyme res subunit
E1A98_RS01415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E1A98_RS01435	COG0582	viral genome integration into host DNA
E1A98_RS01445	COG0583	DNA-binding transcription factor activity
E1A98_RS01450	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E1A98_RS01455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E1A98_RS01460	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E1A98_RS01465	COG2080	2 iron, 2 sulfur cluster binding
E1A98_RS01470	COG3477	response to acidic pH
E1A98_RS01480	COG3121	Chaperone
E1A98_RS01490	COG3188	usher protein
E1A98_RS01520	COG0254	rRNA binding
E1A98_RS01535	COG1388	LysM domain
E1A98_RS01555	COG3059	membrane
E1A98_RS01565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E1A98_RS01570	COG2207	Transcriptional regulator
E1A98_RS01575	COG0247	lactate metabolic process
E1A98_RS01580	COG1139	Iron-sulfur cluster binding protein
E1A98_RS01585	COG1556	Lactate utilization protein
E1A98_RS01610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E1A98_RS01620	COG2771	luxR family
E1A98_RS01620	COG2200	EAL domain
E1A98_RS01625	COG0583	DNA-binding transcription factor activity
E1A98_RS01635	COG0666	response to abiotic stimulus
E1A98_RS01645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E1A98_RS01650	COG1304	FMN binding
E1A98_RS01660	COG0549	Belongs to the carbamate kinase family
E1A98_RS01665	COG0402	S-adenosylhomocysteine deaminase activity
E1A98_RS01670	COG1064	alcohol dehydrogenase
E1A98_RS01685	COG1280	lysine exporter protein (LysE YggA)
E1A98_RS01695	COG3829	transcription factor binding
E1A98_RS01700	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E1A98_RS01705	COG0372	Belongs to the citrate synthase family
E1A98_RS01710	COG2079	MmgE PrpD family protein
E1A98_RS01715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E1A98_RS01720	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E1A98_RS01725	COG0402	S-adenosylhomocysteine deaminase activity
E1A98_RS01730	COG0583	DNA-binding transcription factor activity
E1A98_RS01735	COG0288	reversible hydration of carbon dioxide
E1A98_RS01745	COG2807	transmembrane transport
E1A98_RS01750	COG0110	maltose O-acetyltransferase activity
E1A98_RS01755	COG2223	nitrite transmembrane transporter activity
E1A98_RS01770	COG1609	Transcriptional regulator
E1A98_RS01775	COG1414	Transcriptional regulator
E1A98_RS01785	COG3384	dioxygenase
E1A98_RS01795	COG2826	transposase and inactivated derivatives, IS30 family
E1A98_RS01805	COG3971	2-oxopent-4-enoate hydratase activity
E1A98_RS01820	COG2814	Major facilitator Superfamily
E1A98_RS01825	COG3122	Protein conserved in bacteria
E1A98_RS01835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
E1A98_RS01865	COG1215	transferase activity, transferring glycosyl groups
E1A98_RS01875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E1A98_RS01880	COG4521	taurine ABC transporter
E1A98_RS01885	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E1A98_RS01890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E1A98_RS01895	COG2175	clavaminate synthase activity
E1A98_RS01900	COG0113	porphobilinogen synthase activity
E1A98_RS01905	COG3468	outer membrane autotransporter barrel domain protein
E1A98_RS01920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E1A98_RS01925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E1A98_RS01930	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E1A98_RS01950	COG1181	Belongs to the D-alanine--D-alanine ligase family
E1A98_RS01960	COG1785	Belongs to the alkaline phosphatase family
E1A98_RS01970	COG3706	GGDEF domain
E1A98_RS01975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E1A98_RS01995	COG4126	flavin adenine dinucleotide binding
E1A98_RS02020	COG1940	carbohydrate kinase activity
E1A98_RS02025	COG2814	Major facilitator Superfamily
E1A98_RS02030	COG0419	ATPase involved in DNA repair
E1A98_RS02035	COG0420	3'-5' exonuclease activity
E1A98_RS02040	COG0745	RESPONSE REGULATOR receiver
E1A98_RS02045	COG5002	protein histidine kinase activity
E1A98_RS02050	COG1114	Component of the transport system for branched-chain amino acids
E1A98_RS02055	COG1113	amino acid transport
E1A98_RS02060	COG0366	Alpha amylase catalytic
E1A98_RS02080	COG1862	Preprotein translocase
E1A98_RS02085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E1A98_RS02090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E1A98_RS02095	COG1403	HNH endonuclease
E1A98_RS02100	COG3248	Nucleoside-binding outer membrane protein
E1A98_RS02105	COG4238	major outer membrane lipoprotein
E1A98_RS02115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E1A98_RS02115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E1A98_RS02130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E1A98_RS02135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E1A98_RS02140	COG0667	Aldo Keto reductase
E1A98_RS02150	COG0142	geranyltranstransferase activity
E1A98_RS02165	COG0693	protein deglycase activity
E1A98_RS02170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E1A98_RS02180	COG2814	Major facilitator Superfamily
E1A98_RS02190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E1A98_RS02195	COG1845	cytochrome c oxidase, subunit III
E1A98_RS02200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E1A98_RS02205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E1A98_RS02210	COG2223	nitrite transmembrane transporter activity
E1A98_RS02215	COG3056	Lipoprotein
E1A98_RS02220	COG0271	Belongs to the BolA IbaG family
E1A98_RS02240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E1A98_RS02245	COG0776	regulation of translation
E1A98_RS02250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E1A98_RS02255	COG1555	photosystem II stabilization
E1A98_RS02260	COG0824	Thioesterase
E1A98_RS02270	COG4533	DNA binding
E1A98_RS02280	COG1522	sequence-specific DNA binding
E1A98_RS02285	COG1132	(ABC) transporter
E1A98_RS02290	COG1132	(ABC) transporter
E1A98_RS02295	COG0347	Belongs to the P(II) protein family
E1A98_RS02300	COG0004	ammonium transporteR
E1A98_RS02305	COG1946	Acyl-CoA thioesterase
E1A98_RS02310	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E1A98_RS02315	COG3695	enzyme binding
E1A98_RS02325	COG5507	3-demethylubiquinone-9 3-methyltransferase
E1A98_RS02330	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E1A98_RS02340	COG0110	maltose O-acetyltransferase activity
E1A98_RS02355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E1A98_RS02360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E1A98_RS02365	COG1309	transcriptional regulator
E1A98_RS02370	COG3264	Mechanosensitive ion channel
E1A98_RS02370	COG1196	nuclear chromosome segregation
E1A98_RS02380	COG3923	Primosomal replication protein n
E1A98_RS02385	COG2832	Protein of unknown function (DUF454)
E1A98_RS02395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E1A98_RS02410	COG0326	Molecular chaperone. Has ATPase activity
E1A98_RS02435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS02440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E1A98_RS02440	COG4651	solute:proton antiporter activity
E1A98_RS02445	COG2223	nitrite transmembrane transporter activity
E1A98_RS02450	COG0737	Belongs to the 5'-nucleotidase family
E1A98_RS02455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E1A98_RS02460	COG3735	TraB family
E1A98_RS02470	COG3093	addiction module antidote protein HigA
E1A98_RS02475	COG2217	Heavy metal translocating P-type atpase
E1A98_RS02480	COG2066	Belongs to the glutaminase family
E1A98_RS02485	COG0531	amino acid
E1A98_RS02490	COG0789	Transcriptional regulator
E1A98_RS02495	COG1585	Membrane protein implicated in regulation of membrane protease activity
E1A98_RS02500	COG0330	HflC and HflK could
E1A98_RS02505	COG4619	ABC transporter
E1A98_RS02510	COG0390	transport system, permease component
E1A98_RS02515	COG3118	belongs to the thioredoxin family
E1A98_RS02520	COG0300	oxidoreductase activity
E1A98_RS02525	COG2755	lipolytic protein G-D-S-L family
E1A98_RS02530	COG4181	ATPase activity
E1A98_RS02535	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E1A98_RS02540	COG3209	COG3209 Rhs family protein
E1A98_RS02570	COG0583	DNA-binding transcription factor activity
E1A98_RS02580	COG1414	Transcriptional regulator
E1A98_RS02585	COG3960	tartronate-semialdehyde synthase activity
E1A98_RS02590	COG3622	Belongs to the hyi family
E1A98_RS02595	COG2084	Dehydrogenase
E1A98_RS02600	COG1953	Uracil, thiamine, allantoin
E1A98_RS02610	COG2233	PERMEase
E1A98_RS02615	COG1929	Belongs to the glycerate kinase type-1 family
E1A98_RS02620	COG3257	ureidoglycine aminohydrolase activity
E1A98_RS02625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E1A98_RS02630	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E1A98_RS02635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E1A98_RS02640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E1A98_RS02650	COG0549	Belongs to the carbamate kinase family
E1A98_RS02655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E1A98_RS02660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E1A98_RS02670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E1A98_RS02680	COG1988	membrane-bound metal-dependent
E1A98_RS02685	COG2501	S4 domain
E1A98_RS02695	COG3539	Fimbrial protein
E1A98_RS02700	COG3121	Chaperone
E1A98_RS02705	COG3188	usher protein
E1A98_RS02710	COG3539	Fimbrial protein
E1A98_RS02715	COG3539	Fimbrial protein
E1A98_RS02720	COG2197	response regulator
E1A98_RS02730	COG0582	viral genome integration into host DNA
E1A98_RS02760	COG2076	Multidrug Resistance protein
E1A98_RS02770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E1A98_RS02775	COG1881	PFAM PEBP family protein
E1A98_RS02780	COG2207	Transcriptional regulator
E1A98_RS02820	COG3039	Transposase
E1A98_RS02835	COG3772	lysozyme
E1A98_RS02850	COG5562	phage envelope protein
E1A98_RS02865	COG4220	transposase activity
E1A98_RS02880	COG0500	methyltransferase
E1A98_RS02890	COG2207	Transcriptional regulator
E1A98_RS02895	COG4571	Outer membrane protease
E1A98_RS02900	COG2207	Transcriptional regulator
E1A98_RS02910	COG4783	chaperone-mediated protein folding
E1A98_RS02915	COG1215	transferase activity, transferring glycosyl groups
E1A98_RS02920	COG5002	protein histidine kinase activity
E1A98_RS02925	COG0745	RESPONSE REGULATOR receiver
E1A98_RS02930	COG1538	Outer membrane efflux protein
E1A98_RS02935	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E1A98_RS02940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E1A98_RS02945	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E1A98_RS02950	COG1113	amino acid transport
E1A98_RS02955	COG0668	transmembrane transport
E1A98_RS02960	COG0778	Nitroreductase
E1A98_RS02965	COG2315	Protein conserved in bacteria
E1A98_RS02990	COG3385	transposase activity
E1A98_RS02995	COG2977	Belongs to the P-Pant transferase superfamily
E1A98_RS03000	COG4771	TonB-dependent receptor
E1A98_RS03005	COG2382	esterase
E1A98_RS03010	COG3251	PFAM MbtH domain protein
E1A98_RS03015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E1A98_RS03015	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E1A98_RS03020	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E1A98_RS03025	COG1120	ATPase activity
E1A98_RS03030	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A98_RS03035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A98_RS03045	COG4592	Periplasmic binding protein
E1A98_RS03050	COG1169	isochorismate synthase
E1A98_RS03055	COG1021	2,3-dihydroxybenzoate-AMP ligase
E1A98_RS03060	COG1535	isochorismatase
E1A98_RS03060	COG3433	isochorismatase activity
E1A98_RS03065	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS03070	COG2050	protein possibly involved in aromatic compounds catabolism
E1A98_RS03075	COG1966	Carbon starvation protein
E1A98_RS03080	COG2879	small protein
E1A98_RS03085	COG0371	Dehydrogenase
E1A98_RS03090	COG0436	Aminotransferase
E1A98_RS03095	COG1475	DNA binding
E1A98_RS03100	COG3969	phosphoadenosine phosphosulfate
E1A98_RS03105	COG0583	DNA-binding transcription factor activity
E1A98_RS03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E1A98_RS03115	COG0450	alkyl hydroperoxide reductase
E1A98_RS03120	COG3634	alkyl hydroperoxide reductase activity
E1A98_RS03125	COG0589	response to stress
E1A98_RS03130	COG1063	alcohol dehydrogenase
E1A98_RS03135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E1A98_RS03140	COG3719	Belongs to the RNase T2 family
E1A98_RS03145	COG0471	metal ion transport
E1A98_RS03160	COG3051	citrate lyase alpha subunit
E1A98_RS03165	COG2301	Belongs to the HpcH HpaI aldolase family
E1A98_RS03175	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E1A98_RS03180	COG3290	protein histidine kinase activity
E1A98_RS03185	COG4565	transcriptional regulatory protein
E1A98_RS03190	COG3069	C4-dicarboxylate transmembrane transporter activity
E1A98_RS03200	COG1278	Cold shock
E1A98_RS03215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E1A98_RS03225	COG0583	DNA-binding transcription factor activity
E1A98_RS03240	COG1686	Belongs to the peptidase S11 family
E1A98_RS03245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E1A98_RS03250	COG0772	Belongs to the SEDS family
E1A98_RS03255	COG0768	penicillin binding
E1A98_RS03265	COG0799	negative regulation of ribosome biogenesis
E1A98_RS03270	COG0406	alpha-ribazole phosphatase activity
E1A98_RS03280	COG1466	dna polymerase III delta subunit
E1A98_RS03295	COG2888	peptidyl-tyrosine sulfation
E1A98_RS03300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E1A98_RS03310	COG2214	Heat shock protein DnaJ domain protein
E1A98_RS03315	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E1A98_RS03325	COG2214	Heat shock protein DnaJ domain protein
E1A98_RS03330	COG0443	Heat shock 70 kDa protein
E1A98_RS03340	COG1126	abc transporter atp-binding protein
E1A98_RS03345	COG0765	amino acid transport
E1A98_RS03350	COG0765	amino acid transport
E1A98_RS03355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A98_RS03360	COG3039	Transposase
E1A98_RS03365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
E1A98_RS03370	COG4535	Mg2 and Co2 transporter CorC
E1A98_RS03380	COG1702	phosphate starvation-inducible protein PhoH
E1A98_RS03390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E1A98_RS03430	COG0367	asparagine synthase
E1A98_RS03435	COG0647	UMP catabolic process
E1A98_RS03440	COG1940	carbohydrate kinase activity
E1A98_RS03440	COG1846	Transcriptional regulator
E1A98_RS03445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E1A98_RS03455	COG2190	(PTS) system
E1A98_RS03455	COG1263	PTS System
E1A98_RS03455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS03475	COG0735	belongs to the Fur family
E1A98_RS03485	COG0716	FMN binding
E1A98_RS03495	COG0596	Alpha beta hydrolase
E1A98_RS03500	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
E1A98_RS03505	COG0033	Phosphoglucomutase
E1A98_RS03525	COG0531	amino acid
E1A98_RS03530	COG1982	Orn Lys Arg decarboxylase major
E1A98_RS03540	COG0745	RESPONSE REGULATOR receiver
E1A98_RS03545	COG2205	protein histidine kinase activity
E1A98_RS03575	COG3209	COG3209 Rhs family protein
E1A98_RS03610	COG3272	Protein of unknown function (DUF1722)
E1A98_RS03615	COG0415	Belongs to the DNA photolyase family
E1A98_RS03620	COG3104	oligopeptide transport
E1A98_RS03625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E1A98_RS03630	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E1A98_RS03635	COG1984	allophanate hydrolase subunit 2
E1A98_RS03650	COG3180	Ammonia monooxygenase
E1A98_RS03655	COG3539	Fimbrial protein
E1A98_RS03660	COG3121	Chaperone
E1A98_RS03665	COG3188	usher protein
E1A98_RS03670	COG3539	Fimbrial protein
E1A98_RS03675	COG0372	Belongs to the citrate synthase family
E1A98_RS03685	COG2009	succinate dehydrogenase
E1A98_RS03690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E1A98_RS03695	COG1053	succinate dehydrogenase
E1A98_RS03700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E1A98_RS03705	COG0567	Dehydrogenase, E1 component
E1A98_RS03710	COG0508	dehydrogenase complex catalyzes the overall conversion of
E1A98_RS03720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E1A98_RS03725	COG2188	Transcriptional regulator
E1A98_RS03730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS03730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS03730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS03735	COG0383	alpha-mannosidase activity
E1A98_RS03740	COG1271	oxidase subunit
E1A98_RS03745	COG1294	oxidase, subunit
E1A98_RS03750	COG4890	Cyd operon protein YbgT
E1A98_RS03755	COG3790	cyd operon protein YbgE
E1A98_RS03760	COG0824	Thioesterase
E1A98_RS03765	COG0811	peptide transport
E1A98_RS03770	COG0848	biopolymer transport protein
E1A98_RS03775	COG3064	Membrane
E1A98_RS03785	COG2885	chlorophyll binding
E1A98_RS03790	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E1A98_RS03840	COG3201	nicotinamide mononucleotide transporter
E1A98_RS03845	COG1230	cation diffusion facilitator family transporter
E1A98_RS03855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E1A98_RS03865	COG2017	converts alpha-aldose to the beta-anomer
E1A98_RS03875	COG1085	galactose-1-phosphate uridylyltransferase
E1A98_RS03880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E1A98_RS03885	COG1119	ATPase activity
E1A98_RS03890	COG2005	Transcriptional regulator
E1A98_RS03890	COG3585	molybdate ion transport
E1A98_RS03900	COG0725	ABC transporter, periplasmic molybdate-binding protein
E1A98_RS03905	COG4149	molybdate abc transporter
E1A98_RS03910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
E1A98_RS03915	COG0561	phosphatase activity
E1A98_RS03925	COG0583	DNA-binding transcription factor activity
E1A98_RS03930	COG2828	Protein conserved in bacteria
E1A98_RS03935	COG0471	metal ion transport
E1A98_RS03940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E1A98_RS03945	COG4677	pectinesterase activity
E1A98_RS03950	COG1881	PFAM PEBP family protein
E1A98_RS03955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E1A98_RS03970	COG2226	methyltransferase
E1A98_RS03975	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E1A98_RS03985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E1A98_RS03995	COG0521	Mo-molybdopterin cofactor biosynthetic process
E1A98_RS04005	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E1A98_RS04010	COG0314	molybdopterin synthase activity
E1A98_RS04015	COG0670	Belongs to the BI1 family
E1A98_RS04020	COG0670	Belongs to the BI1 family
E1A98_RS04025	COG0392	lysyltransferase activity
E1A98_RS04030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A98_RS04035	COG3568	Endonuclease Exonuclease Phosphatase
E1A98_RS04045	COG0842	Transport permease protein
E1A98_RS04050	COG0842	Transport permease protein
E1A98_RS04055	COG1131	(ABC) transporter
E1A98_RS04065	COG1309	transcriptional regulator
E1A98_RS04070	COG0513	Belongs to the DEAD box helicase family
E1A98_RS04075	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
E1A98_RS04080	COG1199	ATP-dependent helicase activity
E1A98_RS04085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E1A98_RS04090	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E1A98_RS04100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E1A98_RS04110	COG4774	siderophore transport
E1A98_RS04125	COG0668	transmembrane transport
E1A98_RS04130	COG1126	abc transporter atp-binding protein
E1A98_RS04135	COG0765	amino acid transport
E1A98_RS04140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A98_RS04150	COG5006	permease, DMT superfamily
E1A98_RS04160	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E1A98_RS04165	COG2194	sulfuric ester hydrolase activity
E1A98_RS04175	COG1321	iron dependent repressor
E1A98_RS04180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E1A98_RS04185	COG1376	ErfK ybiS ycfS ynhG family protein
E1A98_RS04190	COG0488	(ABC) transporter
E1A98_RS04200	COG0561	phosphatase activity
E1A98_RS04210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E1A98_RS04215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E1A98_RS04220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E1A98_RS04225	COG0303	'Molybdopterin
E1A98_RS04230	COG1446	asparaginase
E1A98_RS04235	COG4172	Belongs to the ABC transporter superfamily
E1A98_RS04240	COG0747	negative chemotaxis
E1A98_RS04250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1A98_RS04255	COG2200	EAL domain
E1A98_RS04260	COG2199	diguanylate cyclase activity
E1A98_RS04275	COG2133	pyrroloquinoline quinone binding
E1A98_RS04280	COG0625	glutathione transferase activity
E1A98_RS04285	COG1686	Belongs to the peptidase S11 family
E1A98_RS04290	COG1349	DNA-binding transcription factor activity
E1A98_RS04295	COG0671	phosphoesterase, PA-phosphatase related
E1A98_RS04300	COG2814	Major facilitator Superfamily
E1A98_RS04310	COG0561	phosphatase activity
E1A98_RS04315	COG0738	Major facilitator superfamily
E1A98_RS04320	COG3226	Transcriptional regulator
E1A98_RS04335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E1A98_RS04345	COG0778	Nitroreductase
E1A98_RS04360	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E1A98_RS04365	COG3842	ATPase activity
E1A98_RS04370	COG1176	ABC-type spermidine putrescine transport system, permease component I
E1A98_RS04375	COG1177	transmembrane transport
E1A98_RS04390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A98_RS04395	COG4160	amino acid transport
E1A98_RS04400	COG4215	(ABC) transporter
E1A98_RS04405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A98_RS04410	COG1126	abc transporter atp-binding protein
E1A98_RS04425	COG3023	N-Acetylmuramoyl-L-alanine amidase
E1A98_RS04430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1A98_RS04435	COG0702	epimerase
E1A98_RS04440	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E1A98_RS04445	COG0028	Belongs to the TPP enzyme family
E1A98_RS04450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E1A98_RS04460	COG2431	L-lysine efflux transmembrane transporter activity
E1A98_RS04465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E1A98_RS04470	COG3593	DNA synthesis involved in DNA repair
E1A98_RS04475	COG2990	Protein conserved in bacteria
E1A98_RS04480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E1A98_RS04485	COG1136	(ABC) transporter
E1A98_RS04485	COG0577	efflux transmembrane transporter activity
E1A98_RS04490	COG1278	Cold shock
E1A98_RS04500	COG0542	response to heat
E1A98_RS04525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E1A98_RS04530	COG4988	ABC transporter
E1A98_RS04535	COG0492	ferredoxin-NADP+ reductase activity
E1A98_RS04540	COG1522	sequence-specific DNA binding
E1A98_RS04545	COG1178	ABC-type Fe3 transport system permease component
E1A98_RS04545	COG1674	ftsk spoiiie
E1A98_RS04555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E1A98_RS04565	COG0243	molybdopterin cofactor binding
E1A98_RS04570	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS04575	COG3302	dmso reductase anchor subunit
E1A98_RS04580	COG1335	isochorismatase
E1A98_RS04590	COG0531	amino acid
E1A98_RS04595	COG0583	DNA-binding transcription factor activity
E1A98_RS04600	COG2249	NAD(P)H dehydrogenase (quinone) activity
E1A98_RS04605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E1A98_RS04610	COG1882	Formate acetyltransferase
E1A98_RS04615	COG2116	formate transmembrane transporter activity
E1A98_RS04620	COG1944	ATP diphosphatase activity
E1A98_RS04625	COG2323	membrane
E1A98_RS04640	COG0501	Belongs to the peptidase M48B family
E1A98_RS04650	COG0539	negative regulation of cytoplasmic translation
E1A98_RS04660	COG0658	competence protein
E1A98_RS04660	COG2333	competence protein COMEC
E1A98_RS04665	COG1132	(ABC) transporter
E1A98_RS04670	COG1663	tetraacyldisaccharide 4'-kinase activity
E1A98_RS04675	COG3214	Protein conserved in bacteria
E1A98_RS04690	COG3173	Aminoglycoside phosphotransferase
E1A98_RS04695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E1A98_RS04700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E1A98_RS04710	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E1A98_RS04720	COG2989	Protein conserved in bacteria
E1A98_RS04725	COG3108	Peptidase M15
E1A98_RS04730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A98_RS04735	COG1448	Aminotransferase
E1A98_RS04740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E1A98_RS04755	COG0308	aminopeptidase N
E1A98_RS04760	COG1116	anion transmembrane transporter activity
E1A98_RS04765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E1A98_RS04775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E1A98_RS04780	COG0431	NADPH-dependent FMN reductase
E1A98_RS04785	COG3539	Fimbrial protein
E1A98_RS04790	COG3121	Chaperone
E1A98_RS04795	COG3188	usher protein
E1A98_RS04800	COG3539	Fimbrial protein
E1A98_RS04805	COG3539	Fimbrial protein
E1A98_RS04810	COG3539	Fimbrial protein
E1A98_RS04815	COG3121	Chaperone
E1A98_RS04830	COG0633	Ferredoxin
E1A98_RS04830	COG3217	Mosc domain protein beta barrel domain protein
E1A98_RS04840	COG0488	(ABC) transporter
E1A98_RS04845	COG2995	paraquat-inducible protein a
E1A98_RS04850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E1A98_RS04850	COG3008	intermembrane lipid transfer
E1A98_RS04855	COG3009	Protein conserved in bacteria
E1A98_RS04860	COG3130	regulation of translation
E1A98_RS04870	COG1067	ATP-dependent peptidase activity
E1A98_RS04880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E1A98_RS04880	COG2885	chlorophyll binding
E1A98_RS04890	COG3070	regulator of competence-specific genes
E1A98_RS04895	COG1289	transmembrane transporter activity
E1A98_RS04900	COG3304	Inner membrane component domain
E1A98_RS04905	COG0210	DNA helicase
E1A98_RS04920	COG1832	CoA-binding protein
E1A98_RS04935	COG1254	Belongs to the acylphosphatase family
E1A98_RS04940	COG2920	part of a sulfur-relay system
E1A98_RS04945	COG0670	Belongs to the BI1 family
E1A98_RS04955	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E1A98_RS04960	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E1A98_RS04965	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
E1A98_RS04970	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E1A98_RS04975	COG1999	signal sequence binding
E1A98_RS04980	COG1773	rubredoxin
E1A98_RS04985	COG1271	oxidase subunit
E1A98_RS04990	COG1294	oxidase, subunit
E1A98_RS05005	COG0489	protein tyrosine kinase activity
E1A98_RS05005	COG3206	protein involved in exopolysaccharide biosynthesis
E1A98_RS05010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E1A98_RS05015	COG1596	polysaccharide export
E1A98_RS05020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E1A98_RS05045	COG1278	Cold shock
E1A98_RS05050	COG1278	Cold shock
E1A98_RS05070	COG0348	domain, Protein
E1A98_RS05075	COG2205	protein histidine kinase activity
E1A98_RS05075	COG2198	Histidine kinase
E1A98_RS05075	COG0784	Response regulator, receiver
E1A98_RS05080	COG1879	ABC-type sugar transport system periplasmic component
E1A98_RS05085	COG0745	RESPONSE REGULATOR receiver
E1A98_RS05090	COG3005	denitrification pathway
E1A98_RS05095	COG0243	molybdopterin cofactor binding
E1A98_RS05100	COG3381	protein complex oligomerization
E1A98_RS05135	COG3729	General stress protein
E1A98_RS05140	COG2233	PERMEase
E1A98_RS05155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E1A98_RS05180	COG1309	transcriptional regulator
E1A98_RS05185	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E1A98_RS05185	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E1A98_RS05185	COG0506	proline dehydrogenase activity
E1A98_RS05195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E1A98_RS05205	COG2822	iron ion transport
E1A98_RS05210	COG2837	iron assimilation
E1A98_RS05215	COG1702	phosphate starvation-inducible protein PhoH
E1A98_RS05220	COG3658	cytochrome
E1A98_RS05225	COG1215	transferase activity, transferring glycosyl groups
E1A98_RS05230	COG0726	polysaccharide deacetylase
E1A98_RS05230	COG1649	PFAM Uncharacterised BCR, COG1649
E1A98_RS05235	COG0457	Tetratricopeptide repeat
E1A98_RS05240	COG3706	GGDEF domain
E1A98_RS05290	COG3381	protein complex oligomerization
E1A98_RS05300	COG1462	curli production assembly transport component CsgG
E1A98_RS05315	COG2197	response regulator
E1A98_RS05330	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E1A98_RS05335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A98_RS05350	COG2943	transferase activity, transferring hexosyl groups
E1A98_RS05355	COG5645	(Lipo)protein
E1A98_RS05370	COG1560	Kdo2-lipid A biosynthetic process
E1A98_RS05380	COG2353	YceI-like domain
E1A98_RS05385	COG3038	cytochrome b561
E1A98_RS05420	COG2999	glutathione oxidoreductase activity
E1A98_RS05430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A98_RS05440	COG0673	inositol 2-dehydrogenase activity
E1A98_RS05445	COG0728	peptidoglycan biosynthetic process
E1A98_RS05450	COG3418	PFAM FlgN family protein
E1A98_RS05455	COG2747	anti-sigma28 factor FlgM
E1A98_RS05460	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
E1A98_RS05465	COG1815	bacterial-type flagellum-dependent cell motility
E1A98_RS05470	COG1558	bacterial-type flagellum-dependent cell motility
E1A98_RS05475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
E1A98_RS05480	COG1749	Flagellar hook protein flgE
E1A98_RS05485	COG4787	bacterial-type flagellum-dependent cell motility
E1A98_RS05490	COG4786	Flagellar basal body rod
E1A98_RS05505	COG3951	Flagellar rod assembly protein muramidase FlgJ
E1A98_RS05505	COG1705	Flagellar rod assembly protein muramidase FlgJ
E1A98_RS05510	COG1256	bacterial-type flagellum assembly
E1A98_RS05515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E1A98_RS05520	COG1530	ribonuclease E activity
E1A98_RS05530	COG0564	pseudouridine synthase activity
E1A98_RS05540	COG1399	metal-binding, possibly nucleic acid-binding protein
E1A98_RS05560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E1A98_RS05565	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS05575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E1A98_RS05580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E1A98_RS05585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E1A98_RS05595	COG0470	DNA polymerase III
E1A98_RS05600	COG0084	hydrolase, TatD family'
E1A98_RS05605	COG1263	PTS System
E1A98_RS05605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS05610	COG4773	Receptor
E1A98_RS05615	COG0537	adenosine 5'-monophosphoramidase activity
E1A98_RS05620	COG5633	Lipoprotein
E1A98_RS05625	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
E1A98_RS05645	COG1252	NADH dehydrogenase
E1A98_RS05650	COG3134	Outer membrane lipoprotein
E1A98_RS05655	COG1309	transcriptional regulator
E1A98_RS05665	COG1388	LysM domain
E1A98_RS05665	COG1376	ErfK ybiS ycfS ynhG family protein
E1A98_RS05670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E1A98_RS05675	COG4763	Acyl-transferase
E1A98_RS05680	COG4591	ABC-type transport system involved in lipoprotein release permease component
E1A98_RS05685	COG1136	(ABC) transporter
E1A98_RS05690	COG4591	ABC-type transport system involved in lipoprotein release permease component
E1A98_RS05700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E1A98_RS05705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E1A98_RS05715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E1A98_RS05720	COG1177	transmembrane transport
E1A98_RS05725	COG1176	ABC-type spermidine putrescine transport system, permease component I
E1A98_RS05730	COG3842	ATPase activity
E1A98_RS05740	COG2850	peptidyl-arginine hydroxylation
E1A98_RS05745	COG2205	protein histidine kinase activity
E1A98_RS05750	COG0745	RESPONSE REGULATOR receiver
E1A98_RS05755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E1A98_RS05775	COG1187	pseudouridine synthase activity
E1A98_RS05780	COG0538	isocitrate dehydrogenase activity
E1A98_RS05785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E1A98_RS05800	COG0582	viral genome integration into host DNA
E1A98_RS05825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E1A98_RS05830	COG4197	protein conserved in bacteria, prophage-related
E1A98_RS05845	COG1802	Transcriptional regulator
E1A98_RS05845	COG4626	Terminase
E1A98_RS05855	COG4695	Portal protein
E1A98_RS05860	COG3299	homolog of phage Mu protein gp47
E1A98_RS05865	COG3778	Protein conserved in bacteria
E1A98_RS05880	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E1A98_RS05890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E1A98_RS05895	COG1403	HNH endonuclease
E1A98_RS05900	COG0538	isocitrate dehydrogenase activity
E1A98_RS05915	COG5562	phage envelope protein
E1A98_RS05920	COG0789	Transcriptional regulator
E1A98_RS05925	COG2200	EAL domain
E1A98_RS05950	COG2200	EAL domain
E1A98_RS06000	COG2894	cell division
E1A98_RS06025	COG0179	Fumarylacetoacetate (FAA) hydrolase
E1A98_RS06040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E1A98_RS06045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E1A98_RS06050	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E1A98_RS06065	COG2719	SpoVR family
E1A98_RS06075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E1A98_RS06085	COG1619	proteins homologs of microcin C7 resistance protein MccF
E1A98_RS06095	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
E1A98_RS06100	COG2261	transglycosylase associated protein
E1A98_RS06115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS06115	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
E1A98_RS06115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E1A98_RS06120	COG1461	Dihydroxyacetone kinase
E1A98_RS06125	COG2376	Dihydroxyacetone kinase
E1A98_RS06130	COG3284	Transcriptional regulator
E1A98_RS06135	COG3468	outer membrane autotransporter barrel domain protein
E1A98_RS06140	COG0012	GTP binding
E1A98_RS06155	COG0659	secondary active sulfate transmembrane transporter activity
E1A98_RS06160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E1A98_RS06165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
E1A98_RS06175	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
E1A98_RS06185	COG2890	protein-(glutamine-N5) methyltransferase activity
E1A98_RS06190	COG3094	Invasion gene expression up-regulator, SirB
E1A98_RS06195	COG2912	Transglutaminase-like superfamily
E1A98_RS06225	COG0387	Pfam Sodium calcium exchanger
E1A98_RS06230	COG4572	Cation transport regulator
E1A98_RS06235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
E1A98_RS06240	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E1A98_RS06245	COG4932	domain protein
E1A98_RS06250	COG2197	response regulator
E1A98_RS06255	COG3850	Histidine kinase
E1A98_RS06260	COG2223	nitrite transmembrane transporter activity
E1A98_RS06265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E1A98_RS06270	COG1140	nitrate reductase beta subunit
E1A98_RS06275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E1A98_RS06280	COG2181	nitrate reductase activity
E1A98_RS06315	COG0788	formyltetrahydrofolate deformylase activity
E1A98_RS06325	COG1752	Esterase of the alpha-beta hydrolase superfamily
E1A98_RS06330	COG0745	RESPONSE REGULATOR receiver
E1A98_RS06335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E1A98_RS06340	COG2916	Histone family protein nucleoid-structuring protein H-NS
E1A98_RS06345	COG1435	thymidine kinase activity
E1A98_RS06355	COG1454	alcohol dehydrogenase
E1A98_RS06355	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS06360	COG2095	MarC family integral membrane protein
E1A98_RS06365	COG4166	transmembrane transport
E1A98_RS06370	COG0601	transmembrane transport
E1A98_RS06375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1A98_RS06380	COG0444	Belongs to the ABC transporter superfamily
E1A98_RS06385	COG4608	Belongs to the ABC transporter superfamily
E1A98_RS06405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E1A98_RS06410	COG2350	Protein conserved in bacteria
E1A98_RS06415	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
E1A98_RS06420	COG1607	acyl-coa hydrolase
E1A98_RS06440	COG3047	cAMP biosynthetic process
E1A98_RS06445	COG3685	Protein conserved in bacteria
E1A98_RS06450	COG3685	Protein conserved in bacteria
E1A98_RS06455	COG3729	General stress protein
E1A98_RS06470	COG0135	phosphoribosylanthranilate isomerase activity
E1A98_RS06470	COG0134	indole-3-glycerol-phosphate synthase activity
E1A98_RS06475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E1A98_RS06475	COG0512	Glutamine amidotransferase of anthranilate synthase
E1A98_RS06480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E1A98_RS06490	COG0613	PHP domain protein
E1A98_RS06495	COG0009	L-threonylcarbamoyladenylate synthase
E1A98_RS06500	COG4907	membrane protein (DUF2207)
E1A98_RS06505	COG1187	pseudouridine synthase activity
E1A98_RS06510	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
E1A98_RS06515	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS06520	COG0616	signal peptide processing
E1A98_RS06530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E1A98_RS06535	COG0583	DNA-binding transcription factor activity
E1A98_RS06555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E1A98_RS06565	COG0671	phosphoesterase, PA-phosphatase related
E1A98_RS06570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E1A98_RS06575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E1A98_RS06585	COG0023	Translation Initiation Factor
E1A98_RS06595	COG1349	DNA-binding transcription factor activity
E1A98_RS06605	COG5001	Diguanylate cyclase
E1A98_RS06620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A98_RS06620	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A98_RS06625	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E1A98_RS06630	COG2852	Protein conserved in bacteria
E1A98_RS06635	COG4172	Belongs to the ABC transporter superfamily
E1A98_RS06640	COG4172	Belongs to the ABC transporter superfamily
E1A98_RS06645	COG4171	peptide transport system, permease
E1A98_RS06650	COG4168	peptide transport system, permease
E1A98_RS06655	COG4166	transmembrane transport
E1A98_RS06665	COG0531	amino acid
E1A98_RS06675	COG0174	glutamine synthetase
E1A98_RS06680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
E1A98_RS06685	COG1917	Cupin 2, conserved barrel domain protein
E1A98_RS06685	COG1396	sequence-specific DNA binding
E1A98_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS06695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E1A98_RS06700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E1A98_RS06705	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E1A98_RS06710	COG1842	Phage shock protein A
E1A98_RS06720	COG1983	PspC domain protein
E1A98_RS06730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A98_RS06735	COG0366	Alpha amylase catalytic
E1A98_RS06740	COG1653	transport
E1A98_RS06745	COG1175	transmembrane transport
E1A98_RS06750	COG0395	ABC-type sugar transport system, permease component
E1A98_RS06755	COG1063	alcohol dehydrogenase
E1A98_RS06760	COG1082	Xylose isomerase domain protein TIM barrel
E1A98_RS06765	COG0673	inositol 2-dehydrogenase activity
E1A98_RS06770	COG1554	hydrolase, family 65, central catalytic
E1A98_RS06775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1A98_RS06790	COG1609	Transcriptional regulator
E1A98_RS06795	COG3106	COG3106 Predicted ATPase
E1A98_RS06805	COG3283	Transcriptional regulator of aromatic amino acids metabolism
E1A98_RS06810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E1A98_RS06815	COG4948	Mandelate Racemase Muconate Lactonizing
E1A98_RS06820	COG2866	Carboxypeptidase
E1A98_RS06835	COG1073	alpha beta
E1A98_RS06840	COG0583	DNA-binding transcription factor activity
E1A98_RS06845	COG4166	transmembrane transport
E1A98_RS06850	COG0668	transmembrane transport
E1A98_RS06855	COG3039	Transposase
E1A98_RS06860	COG3182	Iron-regulated membrane protein
E1A98_RS06865	COG0589	response to stress
E1A98_RS06870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E1A98_RS06875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E1A98_RS06880	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
E1A98_RS06885	COG1473	amidohydrolase
E1A98_RS06890	COG1473	amidohydrolase
E1A98_RS06895	COG0583	DNA-binding transcription factor activity
E1A98_RS06900	COG2840	Smr protein MutS2
E1A98_RS06905	COG3706	GGDEF domain
E1A98_RS06915	COG0513	Belongs to the DEAD box helicase family
E1A98_RS06925	COG0582	viral genome integration into host DNA
E1A98_RS06945	COG3723	Recombinational DNA repair protein, rece pathway
E1A98_RS06950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E1A98_RS06990	COG4197	protein conserved in bacteria, prophage-related
E1A98_RS07000	COG3756	Protein conserved in bacteria
E1A98_RS07005	COG1484	DNA-dependent DNA replication
E1A98_RS07010	COG1846	Transcriptional regulator
E1A98_RS07020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E1A98_RS07025	COG1475	DNA binding
E1A98_RS07050	COG3039	Transposase
E1A98_RS07060	COG5301	cellulose 1,4-beta-cellobiosidase activity
E1A98_RS07065	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E1A98_RS07070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E1A98_RS07085	COG0589	response to stress
E1A98_RS07090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E1A98_RS07095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A98_RS07095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E1A98_RS07095	COG0674	pyruvate-flavodoxin oxidoreductase activity
E1A98_RS07095	COG1013	pyruvate-flavodoxin oxidoreductase activity
E1A98_RS07100	COG3042	response to heat
E1A98_RS07105	COG3187	Heat shock protein
E1A98_RS07110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E1A98_RS07115	COG2911	Protein conserved in bacteria
E1A98_RS07125	COG3784	Protein of unknown function (DUF1318)
E1A98_RS07130	COG2207	Transcriptional regulator
E1A98_RS07135	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS07140	COG3733	amine oxidase
E1A98_RS07145	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS07145	COG2030	dehydratase
E1A98_RS07150	COG3396	Phenylacetate-CoA oxygenase
E1A98_RS07155	COG3460	Phenylacetate-CoA oxygenase
E1A98_RS07160	COG3396	Phenylacetate-CoA oxygenase
E1A98_RS07165	COG2151	metal-sulfur cluster biosynthetic enzyme
E1A98_RS07170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E1A98_RS07175	COG1024	Enoyl-CoA hydratase
E1A98_RS07180	COG1024	Enoyl-CoA hydratase
E1A98_RS07185	COG1250	3-hydroxyacyl-CoA dehydrogenase
E1A98_RS07190	COG2050	protein possibly involved in aromatic compounds catabolism
E1A98_RS07195	COG0183	Belongs to the thiolase family
E1A98_RS07200	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
E1A98_RS07205	COG3327	negative regulation of DNA-templated transcription, initiation
E1A98_RS07210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E1A98_RS07230	COG2826	transposase and inactivated derivatives, IS30 family
E1A98_RS07245	COG0667	Aldo Keto reductase
E1A98_RS07255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E1A98_RS07260	COG4589	Belongs to the CDS family
E1A98_RS07265	COG2267	carboxylic ester hydrolase activity
E1A98_RS07270	COG0671	phosphoesterase, PA-phosphatase related
E1A98_RS07270	COG2453	phosphatase
E1A98_RS07280	COG1643	Atp-dependent helicase
E1A98_RS07285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E1A98_RS07290	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS07300	COG3038	cytochrome b561
E1A98_RS07320	COG0840	transmembrane signaling receptor activity
E1A98_RS07325	COG0583	DNA-binding transcription factor activity
E1A98_RS07330	COG5383	Protein conserved in bacteria
E1A98_RS07340	COG2841	Protein conserved in bacteria
E1A98_RS07345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A98_RS07350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E1A98_RS07355	COG1275	C4-dicarboxylate transporter malic acid transport protein
E1A98_RS07360	COG0500	methyltransferase
E1A98_RS07375	COG0675	Transposase, IS605 OrfB family
E1A98_RS07380	COG3135	benzoate transporter
E1A98_RS07385	COG1396	sequence-specific DNA binding
E1A98_RS07390	COG0826	peptidase U32
E1A98_RS07400	COG1724	mRNA binding
E1A98_RS07405	COG1598	PFAM Uncharacterised protein family UPF0150
E1A98_RS07410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A98_RS07415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E1A98_RS07420	COG3842	ATPase activity
E1A98_RS07425	COG1176	ABC-type spermidine putrescine transport system, permease component I
E1A98_RS07430	COG1177	transmembrane transport
E1A98_RS07455	COG3238	Protein conserved in bacteria
E1A98_RS07460	COG1247	-acetyltransferase
E1A98_RS07465	COG2130	NADP-dependent
E1A98_RS07470	COG1802	Transcriptional regulator
E1A98_RS07475	COG4772	TonB-dependent receptor
E1A98_RS07480	COG3391	amine dehydrogenase activity
E1A98_RS07485	COG1113	amino acid transport
E1A98_RS07490	COG0625	glutathione transferase activity
E1A98_RS07505	COG3209	COG3209 Rhs family protein
E1A98_RS07525	COG5433	transposase activity
E1A98_RS07535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E1A98_RS07540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
E1A98_RS07545	COG0384	phenazine biosynthesis protein PhzF
E1A98_RS07550	COG2181	nitrate reductase activity
E1A98_RS07555	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E1A98_RS07560	COG1140	nitrate reductase beta subunit
E1A98_RS07565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E1A98_RS07570	COG2223	nitrite transmembrane transporter activity
E1A98_RS07575	COG4886	Leucine-rich repeat (LRR) protein
E1A98_RS07580	COG4886	Leucine-rich repeat (LRR) protein
E1A98_RS07585	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E1A98_RS07590	COG0697	spore germination
E1A98_RS07595	COG0243	molybdopterin cofactor binding
E1A98_RS07595	COG3383	formate dehydrogenase (NAD+) activity
E1A98_RS07600	COG0243	molybdopterin cofactor binding
E1A98_RS07600	COG3383	formate dehydrogenase (NAD+) activity
E1A98_RS07605	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS07610	COG2864	formate dehydrogenase
E1A98_RS07615	COG3093	addiction module antidote protein HigA
E1A98_RS07620	COG1064	alcohol dehydrogenase
E1A98_RS07640	COG1764	response to oxidative stress
E1A98_RS07645	COG4608	Belongs to the ABC transporter superfamily
E1A98_RS07650	COG0444	Belongs to the ABC transporter superfamily
E1A98_RS07655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1A98_RS07660	COG0601	transmembrane transport
E1A98_RS07665	COG0747	negative chemotaxis
E1A98_RS07670	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E1A98_RS07675	COG2199	diguanylate cyclase activity
E1A98_RS07675	COG2202	Pas domain
E1A98_RS07675	COG2200	EAL domain
E1A98_RS07680	COG3706	GGDEF domain
E1A98_RS07690	COG0531	amino acid
E1A98_RS07695	COG0076	glutamate decarboxylase activity
E1A98_RS07700	COG0612	Peptidase, M16
E1A98_RS07705	COG4771	TonB-dependent receptor
E1A98_RS07710	COG4178	(ABC) transporter
E1A98_RS07720	COG0641	radical SAM
E1A98_RS07725	COG3119	arylsulfatase activity
E1A98_RS07730	COG2207	Transcriptional regulator
E1A98_RS07740	COG0243	molybdopterin cofactor binding
E1A98_RS07745	COG3539	Fimbrial protein
E1A98_RS07750	COG3539	Fimbrial protein
E1A98_RS07755	COG3539	Fimbrial protein
E1A98_RS07770	COG3550	peptidyl-serine autophosphorylation
E1A98_RS07775	COG1396	sequence-specific DNA binding
E1A98_RS07825	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E1A98_RS07835	COG3781	membrane
E1A98_RS07840	COG0246	Mannitol dehydrogenase
E1A98_RS07845	COG2199	diguanylate cyclase activity
E1A98_RS07855	COG2066	Belongs to the glutaminase family
E1A98_RS07860	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS07865	COG0583	DNA-binding transcription factor activity
E1A98_RS07885	COG1846	Transcriptional regulator
E1A98_RS07890	COG4977	sequence-specific DNA binding
E1A98_RS07900	COG0697	spore germination
E1A98_RS07905	COG2814	Major facilitator Superfamily
E1A98_RS07915	COG3706	GGDEF domain
E1A98_RS07920	COG3111	PFAM Bacterial OB fold (BOF) protein
E1A98_RS07925	COG1546	Belongs to the CinA family
E1A98_RS07930	COG0339	signal peptide processing
E1A98_RS07935	COG4221	oxidoreductase activity
E1A98_RS07940	COG1802	Transcriptional regulator
E1A98_RS07950	COG0246	Mannitol dehydrogenase
E1A98_RS07955	COG0477	Major facilitator Superfamily
E1A98_RS07970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E1A98_RS07975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
E1A98_RS07980	COG5301	cellulose 1,4-beta-cellobiosidase activity
E1A98_RS07985	COG4220	transposase activity
E1A98_RS07995	COG5562	phage envelope protein
E1A98_RS08020	COG1278	Cold shock
E1A98_RS08030	COG3772	lysozyme
E1A98_RS08045	COG1278	Cold shock
E1A98_RS08050	COG1278	Cold shock
E1A98_RS08060	COG0484	heat shock protein binding
E1A98_RS08065	COG1403	HNH endonuclease
E1A98_RS08085	COG2026	Addiction module toxin, RelE StbE family
E1A98_RS08090	COG3077	Addiction module antitoxin, RelB DinJ family
E1A98_RS08105	COG2801	Transposase and inactivated derivatives
E1A98_RS08120	COG1396	sequence-specific DNA binding
E1A98_RS08160	COG0582	viral genome integration into host DNA
E1A98_RS08170	COG1063	alcohol dehydrogenase
E1A98_RS08175	COG4948	Mandelate Racemase Muconate Lactonizing
E1A98_RS08190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A98_RS08205	COG0243	molybdopterin cofactor binding
E1A98_RS08210	COG0243	molybdopterin cofactor binding
E1A98_RS08215	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS08220	COG3302	dmso reductase anchor subunit
E1A98_RS08225	COG3381	protein complex oligomerization
E1A98_RS08235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E1A98_RS08240	COG1940	carbohydrate kinase activity
E1A98_RS08245	COG0583	DNA-binding transcription factor activity
E1A98_RS08250	COG2814	Major facilitator Superfamily
E1A98_RS08265	COG3591	Belongs to the peptidase S1B family
E1A98_RS08285	COG0628	permease
E1A98_RS08290	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E1A98_RS08295	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E1A98_RS08305	COG0531	amino acid
E1A98_RS08310	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS08315	COG3136	membrane protein required for alginate biosynthesis
E1A98_RS08320	COG0745	RESPONSE REGULATOR receiver
E1A98_RS08325	COG2205	protein histidine kinase activity
E1A98_RS08335	COG0114	fumarate hydratase activity
E1A98_RS08340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E1A98_RS08340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E1A98_RS08345	COG1482	cell wall glycoprotein biosynthetic process
E1A98_RS08350	COG5339	Protein conserved in bacteria
E1A98_RS08360	COG2211	Major facilitator Superfamily
E1A98_RS08365	COG3250	beta-galactosidase activity
E1A98_RS08370	COG1309	transcriptional regulator
E1A98_RS08375	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS08380	COG1609	Transcriptional regulator
E1A98_RS08385	COG1263	PTS System
E1A98_RS08385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS08390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E1A98_RS08400	COG0673	inositol 2-dehydrogenase activity
E1A98_RS08440	COG4659	FMN binding
E1A98_RS08450	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E1A98_RS08455	COG3104	oligopeptide transport
E1A98_RS08460	COG0625	glutathione transferase activity
E1A98_RS08465	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
E1A98_RS08480	COG3895	Periplasmic Protein
E1A98_RS08490	COG3133	Outer membrane lipoprotein
E1A98_RS08505	COG1566	PFAM secretion protein HlyD family protein
E1A98_RS08510	COG1289	transmembrane transporter activity
E1A98_RS08515	COG2032	superoxide dismutase activity
E1A98_RS08520	COG4989	oxidoreductase activity
E1A98_RS08525	COG3313	Fe-S protein
E1A98_RS08530	COG1309	transcriptional regulator
E1A98_RS08535	COG1902	pentaerythritol trinitrate reductase activity
E1A98_RS08540	COG0346	lactoylglutathione lyase activity
E1A98_RS08545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E1A98_RS08550	COG1201	RNA secondary structure unwinding
E1A98_RS08555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E1A98_RS08560	COG0791	NLP P60 protein
E1A98_RS08565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E1A98_RS08570	COG2814	Major facilitator Superfamily
E1A98_RS08585	COG0583	DNA-binding transcription factor activity
E1A98_RS08590	COG2814	Major facilitator Superfamily
E1A98_RS08595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E1A98_RS08600	COG0307	riboflavin synthase, alpha
E1A98_RS08610	COG3468	outer membrane autotransporter barrel domain protein
E1A98_RS08630	COG4529	Protein conserved in bacteria
E1A98_RS08640	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
E1A98_RS08645	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS08655	COG2414	aldehyde ferredoxin oxidoreductase
E1A98_RS08660	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS08670	COG0469	pyruvate kinase activity
E1A98_RS08675	COG4238	major outer membrane lipoprotein
E1A98_RS08680	COG1376	ErfK ybiS ycfS ynhG family protein
E1A98_RS08695	COG0719	Fe-S assembly protein
E1A98_RS08700	COG0396	ATPase activity
E1A98_RS08705	COG0719	Fe-S assembly protein
E1A98_RS08710	COG0316	Belongs to the HesB IscA family
E1A98_RS08720	COG2050	protein possibly involved in aromatic compounds catabolism
E1A98_RS08725	COG0277	FAD linked oxidase domain protein
E1A98_RS08725	COG0247	lactate metabolic process
E1A98_RS08730	COG0628	permease
E1A98_RS08745	COG0738	Major facilitator superfamily
E1A98_RS08750	COG2271	Major facilitator Superfamily
E1A98_RS08765	COG4670	ketone body catabolic process
E1A98_RS08770	COG1960	acyl-CoA dehydrogenase activity
E1A98_RS08775	COG1917	Cupin 2, conserved barrel domain protein
E1A98_RS08775	COG2207	Transcriptional regulator
E1A98_RS08780	COG2086	electron transfer activity
E1A98_RS08785	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E1A98_RS08790	COG0644	oxidoreductase
E1A98_RS08795	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E1A98_RS08800	COG0318	PFAM AMP-dependent synthetase and ligase
E1A98_RS08805	COG0574	Belongs to the PEP-utilizing enzyme family
E1A98_RS08805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E1A98_RS08815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E1A98_RS08820	COG4256	Hemin uptake protein
E1A98_RS08830	COG2200	EAL domain
E1A98_RS08835	COG0791	NLP P60 protein
E1A98_RS08845	COG0386	Belongs to the glutathione peroxidase family
E1A98_RS08860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E1A98_RS08860	COG0072	phenylalanine-tRNA ligase activity
E1A98_RS08905	COG3137	Salt-induced outer membrane protein
E1A98_RS08910	COG1105	Belongs to the carbohydrate kinase PfkB family
E1A98_RS08930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1A98_RS08935	COG1988	membrane-bound metal-dependent
E1A98_RS08955	COG0753	catalase activity
E1A98_RS08965	COG1486	melibiose metabolic process
E1A98_RS08970	COG1917	Cupin 2, conserved barrel domain protein
E1A98_RS08970	COG2169	Transcriptional regulator
E1A98_RS08975	COG1447	Phosphotransferase system cellobiose-specific component IIA
E1A98_RS08980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E1A98_RS08985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E1A98_RS08995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E1A98_RS09005	COG0322	excinuclease ABC activity
E1A98_RS09015	COG3678	ATP-independent chaperone mediated protein folding
E1A98_RS09035	COG3138	arginine N-succinyltransferase
E1A98_RS09045	COG0708	Exodeoxyribonuclease III
E1A98_RS09050	COG0398	Pfam SNARE associated Golgi protein
E1A98_RS09060	COG0398	Pfam SNARE associated Golgi protein
E1A98_RS09065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A98_RS09070	COG4134	Bacterial extracellular solute-binding protein
E1A98_RS09075	COG4135	transport system, permease component
E1A98_RS09080	COG4136	ATPase activity
E1A98_RS09085	COG2897	thiosulfate sulfurtransferase activity
E1A98_RS09090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E1A98_RS09095	COG0494	nUDIX hydrolase
E1A98_RS09105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E1A98_RS09115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E1A98_RS09125	COG0778	Nitroreductase
E1A98_RS09130	COG0616	signal peptide processing
E1A98_RS09135	COG0252	asparaginase activity
E1A98_RS09140	COG1335	isochorismatase
E1A98_RS09145	COG2814	Major facilitator Superfamily
E1A98_RS09150	COG1349	DNA-binding transcription factor activity
E1A98_RS09155	COG0667	Aldo Keto reductase
E1A98_RS09160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS09165	COG0191	fructose-bisphosphate aldolase activity
E1A98_RS09170	COG1063	alcohol dehydrogenase
E1A98_RS09175	COG2271	Major facilitator Superfamily
E1A98_RS09180	COG1063	alcohol dehydrogenase
E1A98_RS09185	COG3139	Protein of unknown function (DUF1315)
E1A98_RS09195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E1A98_RS09200	COG0676	glucose-6-phosphate 1-epimerase activity
E1A98_RS09205	COG0656	L-ascorbic acid biosynthetic process
E1A98_RS09210	COG3713	MltA-interacting MipA family protein
E1A98_RS09215	COG2766	serine protein kinase
E1A98_RS09225	COG2199	diguanylate cyclase activity
E1A98_RS09230	COG2199	diguanylate cyclase activity
E1A98_RS09235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E1A98_RS09250	COG2207	Transcriptional regulator
E1A98_RS09255	COG2807	transmembrane transport
E1A98_RS09260	COG3189	MarR family transcriptional regulator
E1A98_RS09265	COG3042	response to heat
E1A98_RS09270	COG2199	diguanylate cyclase activity
E1A98_RS09270	COG2203	Gaf domain
E1A98_RS09285	COG2261	transglycosylase associated protein
E1A98_RS09295	COG3615	Tellurite resistance protein tehB
E1A98_RS09305	COG0583	DNA-binding transcription factor activity
E1A98_RS09310	COG0473	3-isopropylmalate dehydrogenase activity
E1A98_RS09315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E1A98_RS09320	COG4638	Rieske (2fe-2S)
E1A98_RS09325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E1A98_RS09330	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E1A98_RS09335	COG0318	PFAM AMP-dependent synthetase and ligase
E1A98_RS09340	COG3065	identical protein binding
E1A98_RS09345	COG1214	PFAM Peptidase M22, glycoprotease
E1A98_RS09350	COG1199	ATP-dependent helicase activity
E1A98_RS09355	COG0251	oxidation-reduction process
E1A98_RS09370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E1A98_RS09380	COG1760	l-serine dehydratase
E1A98_RS09385	COG2200	EAL domain
E1A98_RS09390	COG1253	flavin adenine dinucleotide binding
E1A98_RS09395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS09395	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS09400	COG3715	PTS system
E1A98_RS09405	COG3716	PTS system mannose fructose sorbose family IID component
E1A98_RS09420	COG2226	methyltransferase
E1A98_RS09425	COG1278	Cold shock
E1A98_RS09450	COG1414	Transcriptional regulator
E1A98_RS09455	COG2814	Major facilitator Superfamily
E1A98_RS09465	COG0793	Belongs to the peptidase S41A family
E1A98_RS09475	COG1956	GAF domain-containing protein
E1A98_RS09480	COG2995	paraquat-inducible protein a
E1A98_RS09485	COG3008	intermembrane lipid transfer
E1A98_RS09505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E1A98_RS09515	COG1276	copper resistance
E1A98_RS09520	COG2372	response to copper ion
E1A98_RS09530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E1A98_RS09535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E1A98_RS09540	COG1770	oligopeptidase
E1A98_RS09545	COG2979	Protein of unknown function (DUF533)
E1A98_RS09555	COG3141	response to X-ray
E1A98_RS09565	COG0800	Aldolase
E1A98_RS09570	COG0129	dihydroxy-acid dehydratase activity
E1A98_RS09575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E1A98_RS09580	COG1737	Transcriptional regulator
E1A98_RS09585	COG0469	pyruvate kinase activity
E1A98_RS09590	COG1560	Kdo2-lipid A biosynthetic process
E1A98_RS09595	COG0739	heme binding
E1A98_RS09600	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E1A98_RS09605	COG1121	(ABC) transporter
E1A98_RS09610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E1A98_RS09640	COG0217	transcriptional regulatory protein
E1A98_RS09645	COG0494	nUDIX hydrolase
E1A98_RS09655	COG1335	isochorismatase
E1A98_RS09660	COG1801	Protein of unknown function DUF72
E1A98_RS09665	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E1A98_RS09680	COG0243	molybdopterin cofactor binding
E1A98_RS09685	COG3005	denitrification pathway
E1A98_RS09695	COG3102	Protein conserved in bacteria
E1A98_RS09705	COG3755	Protein conserved in bacteria
E1A98_RS09715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E1A98_RS09720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E1A98_RS09725	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
E1A98_RS09730	COG0745	RESPONSE REGULATOR receiver
E1A98_RS09735	COG2201	protein-glutamate methylesterase activity
E1A98_RS09740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E1A98_RS09745	COG0840	transmembrane signaling receptor activity
E1A98_RS09750	COG0840	transmembrane signaling receptor activity
E1A98_RS09755	COG0835	chemotaxis
E1A98_RS09760	COG0643	Histidine kinase
E1A98_RS09760	COG2198	Histidine kinase
E1A98_RS09765	COG1360	Flagellar Motor Protein
E1A98_RS09770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E1A98_RS09785	COG0589	response to stress
E1A98_RS09795	COG1877	trehalose-phosphatase activity
E1A98_RS09800	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS09805	COG1129	ABC transporter
E1A98_RS09810	COG1879	ABC-type sugar transport system periplasmic component
E1A98_RS09815	COG1528	Iron-storage protein
E1A98_RS09835	COG1528	Iron-storage protein
E1A98_RS09845	COG0814	amino acid
E1A98_RS09850	COG3318	Belongs to the UPF0149 family
E1A98_RS09850	COG3012	SEC-C Motif Domain Protein
E1A98_RS09870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E1A98_RS09880	COG2197	response regulator
E1A98_RS09895	COG2197	response regulator
E1A98_RS09925	COG1191	sigma factor activity
E1A98_RS09930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E1A98_RS09935	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
E1A98_RS09940	COG1516	flagellar protein fliS
E1A98_RS09950	COG0366	Alpha amylase catalytic
E1A98_RS09960	COG2391	methyltransferase activity
E1A98_RS09965	COG0425	Belongs to the sulfur carrier protein TusA family
E1A98_RS09970	COG2135	peptidase activity
E1A98_RS09975	COG0454	-acetyltransferase
E1A98_RS10000	COG1766	The M ring may be actively involved in energy transduction
E1A98_RS10005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E1A98_RS10010	COG1317	bacterial-type flagellum organization
E1A98_RS10015	COG1157	protein secretion by the type III secretion system
E1A98_RS10020	COG2882	bacterial-type flagellum organization
E1A98_RS10025	COG3144	bacterial-type flagellum assembly
E1A98_RS10030	COG1580	Controls the rotational direction of flagella during chemotaxis
E1A98_RS10035	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E1A98_RS10040	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E1A98_RS10045	COG3190	flagellar
E1A98_RS10050	COG1338	Plays a role in the flagellum-specific transport system
E1A98_RS10055	COG1987	bacterial-type flagellum assembly
E1A98_RS10060	COG1684	flagellar biosynthetic protein fliR
E1A98_RS10065	COG2197	response regulator
E1A98_RS10090	COG3706	GGDEF domain
E1A98_RS10095	COG5475	Uncharacterized small protein (DUF2158)
E1A98_RS10100	COG2354	Protein conserved in bacteria
E1A98_RS10105	COG0697	spore germination
E1A98_RS10110	COG3727	T/G mismatch-specific endonuclease activity
E1A98_RS10115	COG0270	DNA (cytosine-5-)-methyltransferase activity
E1A98_RS10120	COG1418	mRNA catabolic process
E1A98_RS10145	COG2205	protein histidine kinase activity
E1A98_RS10150	COG0745	RESPONSE REGULATOR receiver
E1A98_RS10155	COG2351	hydroxyisourate hydrolase activity
E1A98_RS10160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E1A98_RS10170	COG3443	Belongs to the bacterial solute-binding protein 9 family
E1A98_RS10175	COG3038	cytochrome b561
E1A98_RS10185	COG3228	Belongs to the MtfA family
E1A98_RS10195	COG1470	cell adhesion involved in biofilm formation
E1A98_RS10195	COG1388	LysM domain
E1A98_RS10205	COG0477	Major facilitator Superfamily
E1A98_RS10210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E1A98_RS10225	COG0534	Mate efflux family protein
E1A98_RS10235	COG0583	DNA-binding transcription factor activity
E1A98_RS10240	COG0583	DNA-binding transcription factor activity
E1A98_RS10250	COG1376	ErfK ybiS ycfS ynhG family protein
E1A98_RS10265	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
E1A98_RS10275	COG3039	Transposase
E1A98_RS10310	COG3468	outer membrane autotransporter barrel domain protein
E1A98_RS10315	COG2020	methyltransferase activity
E1A98_RS10320	COG2003	Belongs to the UPF0758 family
E1A98_RS10355	COG4917	ethanolamine utilization protein
E1A98_RS10365	COG1289	transmembrane transporter activity
E1A98_RS10370	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E1A98_RS10375	COG1686	Belongs to the peptidase S11 family
E1A98_RS10380	COG2925	Exonuclease
E1A98_RS10385	COG0425	Belongs to the sulfur carrier protein TusA family
E1A98_RS10390	COG2391	methyltransferase activity
E1A98_RS10395	COG0531	amino acid
E1A98_RS10405	COG0583	DNA-binding transcription factor activity
E1A98_RS10410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1A98_RS10415	COG4115	mRNA cleavage
E1A98_RS10420	COG2161	toxin-antitoxin pair type II binding
E1A98_RS10435	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E1A98_RS10445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E1A98_RS10445	COG0131	Imidazoleglycerol-phosphate dehydratase
E1A98_RS10450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E1A98_RS10465	COG0140	phosphoribosyl-ATP diphosphatase activity
E1A98_RS10465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
E1A98_RS10470	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E1A98_RS10475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
E1A98_RS10480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E1A98_RS10490	COG3039	Transposase
E1A98_RS10500	COG0438	transferase activity, transferring glycosyl groups
E1A98_RS10505	COG0110	maltose O-acetyltransferase activity
E1A98_RS10510	COG0438	transferase activity, transferring glycosyl groups
E1A98_RS10520	COG0562	UDP-galactopyranose mutase
E1A98_RS10525	COG2244	polysaccharide biosynthetic process
E1A98_RS10530	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
E1A98_RS10535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E1A98_RS10540	COG1091	dTDP-4-dehydrorhamnose reductase activity
E1A98_RS10545	COG1088	dTDP-glucose 4,6-dehydratase activity
E1A98_RS10550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E1A98_RS10560	COG0438	transferase activity, transferring glycosyl groups
E1A98_RS10565	COG2327	Polysaccharide pyruvyl transferase
E1A98_RS10570	COG2244	polysaccharide biosynthetic process
E1A98_RS10575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E1A98_RS10580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E1A98_RS10585	COG0662	Cupin 2, conserved barrel domain protein
E1A98_RS10585	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
E1A98_RS10590	COG0297	glycogen (starch) synthase activity
E1A98_RS10595	COG1051	belongs to the nudix hydrolase family
E1A98_RS10600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1A98_RS10605	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E1A98_RS10610	COG0110	maltose O-acetyltransferase activity
E1A98_RS10615	COG1216	Glycosyl transferase, family 2
E1A98_RS10625	COG0438	transferase activity, transferring glycosyl groups
E1A98_RS10630	COG1045	serine acetyltransferase
E1A98_RS10635	COG0463	Glycosyl transferase, family 2
E1A98_RS10640	COG3206	protein involved in exopolysaccharide biosynthesis
E1A98_RS10640	COG0489	protein tyrosine kinase activity
E1A98_RS10645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E1A98_RS10650	COG1596	polysaccharide export
E1A98_RS10655	COG1253	flavin adenine dinucleotide binding
E1A98_RS10660	COG2982	Protein involved in outer membrane biogenesis
E1A98_RS10670	COG0572	uridine kinase
E1A98_RS10675	COG5001	Diguanylate cyclase
E1A98_RS10675	COG3447	MASE1 domain protein
E1A98_RS10675	COG5002	protein histidine kinase activity
E1A98_RS10680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E1A98_RS10685	COG0443	Heat shock 70 kDa protein
E1A98_RS10690	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
E1A98_RS10695	COG3779	Protein conserved in bacteria
E1A98_RS10700	COG0631	protein serine/threonine phosphatase activity
E1A98_RS10705	COG4245	von Willebrand factor, type A
E1A98_RS10740	COG2205	protein histidine kinase activity
E1A98_RS10745	COG0745	RESPONSE REGULATOR receiver
E1A98_RS10750	COG3422	double-strand break repair
E1A98_RS10800	COG1063	alcohol dehydrogenase
E1A98_RS10805	COG3775	system Galactitol-specific IIC component
E1A98_RS10810	COG3414	Phosphotransferase system galactitol-specific IIB component
E1A98_RS10815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS10830	COG1830	Aldolase
E1A98_RS10835	COG2211	Major facilitator Superfamily
E1A98_RS10840	COG1397	ADP-ribosylglycohydrolase
E1A98_RS10845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS10850	COG2188	Transcriptional regulator
E1A98_RS10855	COG3757	hydrolase, family 25
E1A98_RS10860	COG0351	phosphomethylpyrimidine kinase
E1A98_RS10875	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E1A98_RS10880	COG5455	response to cobalt ion
E1A98_RS10885	COG3539	Fimbrial protein
E1A98_RS10890	COG3188	usher protein
E1A98_RS10895	COG3121	Chaperone
E1A98_RS10900	COG3539	Fimbrial protein
E1A98_RS10910	COG0489	protein tyrosine kinase activity
E1A98_RS10925	COG3831	ATPase activity
E1A98_RS10935	COG0714	Associated with various cellular activities
E1A98_RS10940	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E1A98_RS10945	COG3552	Protein containing von Willebrand factor type A (VWA) domain
E1A98_RS10950	COG4715	Zinc finger, swim domain protein
E1A98_RS10955	COG4808	Protein conserved in bacteria
E1A98_RS10960	COG4807	Protein conserved in bacteria
E1A98_RS10965	COG3279	Response regulator of the LytR AlgR family
E1A98_RS10970	COG3275	phosphorelay sensor kinase activity
E1A98_RS10975	COG0789	Transcriptional regulator
E1A98_RS10985	COG1174	glycine betaine transport
E1A98_RS10990	COG1125	glycine betaine transport
E1A98_RS10995	COG1174	glycine betaine transport
E1A98_RS11000	COG1732	Glycine betaine
E1A98_RS11005	COG1472	Belongs to the glycosyl hydrolase 3 family
E1A98_RS11010	COG0277	FAD linked oxidase domain protein
E1A98_RS11015	COG1686	Belongs to the peptidase S11 family
E1A98_RS11025	COG0586	Pfam SNARE associated Golgi protein
E1A98_RS11030	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS11045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E1A98_RS11055	COG1346	cytolysis
E1A98_RS11065	COG2949	membrane
E1A98_RS11075	COG0493	'glutamate synthase
E1A98_RS11080	COG0167	dihydroorotate dehydrogenase activity
E1A98_RS11080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
E1A98_RS11085	COG4211	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS11090	COG1129	ABC transporter
E1A98_RS11095	COG1879	ABC-type sugar transport system periplasmic component
E1A98_RS11100	COG1609	Transcriptional regulator
E1A98_RS11105	COG2311	Membrane
E1A98_RS11120	COG4771	TonB-dependent receptor
E1A98_RS11125	COG0833	amino acid
E1A98_RS11130	COG0583	DNA-binding transcription factor activity
E1A98_RS11135	COG2855	membrane
E1A98_RS11140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
E1A98_RS11145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS11145	COG1522	sequence-specific DNA binding
E1A98_RS11150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A98_RS11160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E1A98_RS11165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A98_RS11170	COG2313	pseudouridylate synthase activity
E1A98_RS11175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS11180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E1A98_RS11180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS11180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS11185	COG1105	Belongs to the carbohydrate kinase PfkB family
E1A98_RS11190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS11190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS11195	COG2814	Major facilitator Superfamily
E1A98_RS11210	COG0246	Mannitol dehydrogenase
E1A98_RS11215	COG0523	cobalamin synthesis protein
E1A98_RS11220	COG0671	phosphoesterase, PA-phosphatase related
E1A98_RS11225	COG0791	NLP P60 protein
E1A98_RS11230	COG2200	EAL domain
E1A98_RS11235	COG4166	transmembrane transport
E1A98_RS11240	COG4174	ABC transporter (Permease)
E1A98_RS11245	COG4239	(ABC) transporter, permease
E1A98_RS11250	COG4172	Belongs to the ABC transporter superfamily
E1A98_RS11260	COG2814	Major facilitator Superfamily
E1A98_RS11265	COG1187	pseudouridine synthase activity
E1A98_RS11270	COG1061	Type III restriction enzyme res subunit
E1A98_RS11290	COG3083	sulfuric ester hydrolase activity
E1A98_RS11300	COG3468	outer membrane autotransporter barrel domain protein
E1A98_RS11305	COG3039	Transposase
E1A98_RS11310	COG2197	response regulator
E1A98_RS11315	COG3088	subunit of a heme lyase
E1A98_RS11315	COG4235	cytochrome complex assembly
E1A98_RS11320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1A98_RS11325	COG1138	Cytochrome C-type biogenesis protein
E1A98_RS11335	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E1A98_RS11340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E1A98_RS11345	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E1A98_RS11355	COG3005	denitrification pathway
E1A98_RS11360	COG3043	anaerobic respiration
E1A98_RS11365	COG0348	domain, Protein
E1A98_RS11370	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS11380	COG3062	negative regulation of establishment of protein localization
E1A98_RS11385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS11385	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS11400	COG4615	Cyclic peptide transporter
E1A98_RS11405	COG3145	DNA-N1-methyladenine dioxygenase activity
E1A98_RS11410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E1A98_RS11410	COG2169	Transcriptional regulator
E1A98_RS11415	COG1477	protein flavinylation
E1A98_RS11420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E1A98_RS11425	COG2198	Histidine kinase
E1A98_RS11425	COG0642	Histidine kinase
E1A98_RS11430	COG2197	response regulator
E1A98_RS11435	COG2205	protein histidine kinase activity
E1A98_RS11435	COG0784	Response regulator, receiver
E1A98_RS11440	COG3852	Histidine kinase
E1A98_RS11445	COG2204	response regulator
E1A98_RS11450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
E1A98_RS11455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E1A98_RS11460	COG2031	fatty acid transporter
E1A98_RS11465	COG0183	Belongs to the thiolase family
E1A98_RS11470	COG4676	Protein conserved in bacteria
E1A98_RS11475	COG5445	Predicted secreted protein (DUF2300)
E1A98_RS11485	COG3234	Protein of unknown function (DUF1175)
E1A98_RS11490	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
E1A98_RS11495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E1A98_RS11505	COG3468	outer membrane autotransporter barrel domain protein
E1A98_RS11510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E1A98_RS11515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E1A98_RS11520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E1A98_RS11525	COG3642	lipopolysaccharide core region biosynthetic process
E1A98_RS11535	COG0584	glycerophosphoryl diester phosphodiesterase
E1A98_RS11540	COG2271	Major facilitator Superfamily
E1A98_RS11545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E1A98_RS11555	COG0247	lactate metabolic process
E1A98_RS11560	COG5464	transposase or invertase
E1A98_RS11575	COG2271	Major facilitator Superfamily
E1A98_RS11585	COG1414	Transcriptional regulator
E1A98_RS11650	COG0318	PFAM AMP-dependent synthetase and ligase
E1A98_RS11660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E1A98_RS11675	COG1169	isochorismate synthase
E1A98_RS11680	COG4575	ribosome binding
E1A98_RS11685	COG2153	protein acetylation
E1A98_RS11695	COG5160	protein modification by small protein removal
E1A98_RS11700	COG2304	oxidoreductase activity
E1A98_RS11705	COG2234	aminopeptidase activity
E1A98_RS11725	COG0457	Tetratricopeptide repeat
E1A98_RS11735	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A98_RS11740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E1A98_RS11750	COG0839	Belongs to the complex I subunit 6 family
E1A98_RS11755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A98_RS11765	COG1034	ATP synthesis coupled electron transport
E1A98_RS11770	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E1A98_RS11775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E1A98_RS11795	COG0583	DNA-binding transcription factor activity
E1A98_RS11800	COG0436	Aminotransferase
E1A98_RS11810	COG0471	metal ion transport
E1A98_RS11810	COG0490	domain, Protein
E1A98_RS11815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1A98_RS11830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E1A98_RS11835	COG0857	belongs to the CobB CobQ family
E1A98_RS11835	COG0280	phosphate acetyltransferase
E1A98_RS11840	COG1288	antiporter activity
E1A98_RS11845	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
E1A98_RS11850	COG0622	Phosphoesterase
E1A98_RS11855	COG0625	glutathione transferase activity
E1A98_RS11860	COG0625	glutathione transferase activity
E1A98_RS11865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E1A98_RS11870	COG1090	epimerase
E1A98_RS11875	COG5464	transposase or invertase
E1A98_RS11880	COG4598	ABC transporter
E1A98_RS11885	COG4160	amino acid transport
E1A98_RS11890	COG4215	(ABC) transporter
E1A98_RS11895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A98_RS11900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A98_RS11905	COG0163	prenyltransferase activity
E1A98_RS11910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E1A98_RS11915	COG1286	toxin biosynthetic process
E1A98_RS11920	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E1A98_RS11925	COG0285	dihydrofolate synthase activity
E1A98_RS11935	COG0586	Pfam SNARE associated Golgi protein
E1A98_RS11945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E1A98_RS11960	COG2814	Major facilitator Superfamily
E1A98_RS11965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E1A98_RS11980	COG3101	peptidyl-lysine hydroxylation
E1A98_RS11985	COG0730	response to heat
E1A98_RS12000	COG2890	protein-(glutamine-N5) methyltransferase activity
E1A98_RS12015	COG3539	Fimbrial protein
E1A98_RS12020	COG3539	Fimbrial protein
E1A98_RS12025	COG3539	Fimbrial protein
E1A98_RS12030	COG3121	Chaperone
E1A98_RS12040	COG3539	Fimbrial protein
E1A98_RS12045	COG2062	phosphohistidine phosphatase, SixA
E1A98_RS12060	COG3691	Protein conserved in bacteria
E1A98_RS12065	COG2067	long-chain fatty acid transport protein
E1A98_RS12075	COG2853	Lipoprotein
E1A98_RS12080	COG2116	formate transmembrane transporter activity
E1A98_RS12090	COG0582	viral genome integration into host DNA
E1A98_RS12095	COG2246	polysaccharide biosynthetic process
E1A98_RS12100	COG0463	Glycosyl transferase, family 2
E1A98_RS12130	COG4725	Belongs to the MT-A70-like family
E1A98_RS12140	COG1846	Transcriptional regulator
E1A98_RS12150	COG5532	Uncharacterized conserved protein (DUF2303)
E1A98_RS12155	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E1A98_RS12170	COG3311	Transcriptional regulator
E1A98_RS12175	COG0583	DNA-binding transcription factor activity
E1A98_RS12180	COG2610	gluconate transmembrane transporter activity
E1A98_RS12190	COG0477	Major facilitator Superfamily
E1A98_RS12195	COG1566	PFAM secretion protein HlyD family protein
E1A98_RS12200	COG2197	response regulator
E1A98_RS12205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A98_RS12205	COG2198	Histidine kinase
E1A98_RS12205	COG2205	protein histidine kinase activity
E1A98_RS12205	COG0784	Response regulator, receiver
E1A98_RS12210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
E1A98_RS12215	COG0679	Auxin Efflux Carrier
E1A98_RS12220	COG0028	Belongs to the TPP enzyme family
E1A98_RS12245	COG1560	Kdo2-lipid A biosynthetic process
E1A98_RS12255	COG0436	Aminotransferase
E1A98_RS12260	COG3275	phosphorelay sensor kinase activity
E1A98_RS12265	COG3279	Response regulator of the LytR AlgR family
E1A98_RS12270	COG2207	Transcriptional regulator
E1A98_RS12275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS12275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS12275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E1A98_RS12280	COG1363	Peptidase, m42
E1A98_RS12285	COG0006	proline dipeptidase activity
E1A98_RS12290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS12295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS12305	COG0038	chloride channel
E1A98_RS12320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A98_RS12325	COG3385	transposase activity
E1A98_RS12330	COG2199	diguanylate cyclase activity
E1A98_RS12330	COG2200	EAL domain
E1A98_RS12345	COG3415	Transposase
E1A98_RS12350	COG3415	Transposase
E1A98_RS12380	COG0583	DNA-binding transcription factor activity
E1A98_RS12390	COG2211	Major facilitator Superfamily
E1A98_RS12395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E1A98_RS12405	COG0583	DNA-binding transcription factor activity
E1A98_RS12410	COG0385	Bile acid
E1A98_RS12415	COG3530	Putative quorum-sensing-regulated virulence factor
E1A98_RS12435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E1A98_RS12440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS12445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E1A98_RS12450	COG2190	(PTS) system
E1A98_RS12465	COG4884	unkown
E1A98_RS12465	COG3831	ATPase activity
E1A98_RS12470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E1A98_RS12475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E1A98_RS12480	COG4208	sulfate ABC transporter
E1A98_RS12485	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
E1A98_RS12490	COG4150	thiosulfate binding
E1A98_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS12510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS12510	COG1263	PTS System
E1A98_RS12515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E1A98_RS12520	COG2837	iron assimilation
E1A98_RS12535	COG0456	acetyltransferase
E1A98_RS12540	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A98_RS12550	COG2207	Transcriptional regulator
E1A98_RS12555	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E1A98_RS12560	COG4816	utilization protein
E1A98_RS12570	COG4303	Ethanolamine ammonia lyase large subunit
E1A98_RS12575	COG0582	viral genome integration into host DNA
E1A98_RS12620	COG4819	ethanolamine utilization protein
E1A98_RS12625	COG3192	ethanolamine utilization protein
E1A98_RS12630	COG1454	alcohol dehydrogenase
E1A98_RS12635	COG4820	ethanolamine utilization protein (EutJ)
E1A98_RS12640	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS12645	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
E1A98_RS12650	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E1A98_RS12655	COG0280	phosphate acetyltransferase
E1A98_RS12660	COG4812	Cobalamin adenosyltransferase
E1A98_RS12665	COG4766	ethanolamine catabolic process
E1A98_RS12670	COG4917	ethanolamine utilization protein
E1A98_RS12675	COG4810	utilization protein
E1A98_RS12680	COG0280	phosphate acetyltransferase
E1A98_RS12680	COG0281	malic enzyme
E1A98_RS12685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E1A98_RS12690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E1A98_RS12695	COG5342	invasion associated locus B
E1A98_RS12705	COG0493	'glutamate synthase
E1A98_RS12705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS12710	COG3850	Histidine kinase
E1A98_RS12715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E1A98_RS12725	COG1393	Belongs to the ArsC family
E1A98_RS12740	COG0400	carboxylic ester hydrolase activity
E1A98_RS12745	COG1444	tRNA N-acetyltransferase activity
E1A98_RS12750	COG2321	neutral zinc metallopeptidase
E1A98_RS12760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E1A98_RS12770	COG2716	regulation of RNA biosynthetic process
E1A98_RS12775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E1A98_RS12780	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS12785	COG0651	ATP synthesis coupled electron transport
E1A98_RS12790	COG0650	Formate hydrogenlyase subunit 4
E1A98_RS12795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E1A98_RS12800	COG4237	Hydrogenase 4 membrane
E1A98_RS12805	COG0651	ATP synthesis coupled electron transport
E1A98_RS12810	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E1A98_RS12810	COG3261	NADH dehydrogenase
E1A98_RS12815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A98_RS12820	COG3260	NADH ubiquinone oxidoreductase 20
E1A98_RS12830	COG3604	Transcriptional regulator
E1A98_RS12835	COG2116	formate transmembrane transporter activity
E1A98_RS12840	COG0628	permease
E1A98_RS12845	COG4783	chaperone-mediated protein folding
E1A98_RS12850	COG1393	Belongs to the ArsC family
E1A98_RS12860	COG2233	PERMEase
E1A98_RS12875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E1A98_RS12880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E1A98_RS12885	COG0248	Ppx GppA phosphatase
E1A98_RS12890	COG2200	EAL domain
E1A98_RS12900	COG3133	Outer membrane lipoprotein
E1A98_RS12915	COG0516	GMP reductase activity
E1A98_RS12915	COG0517	IMP dehydrogenase activity
E1A98_RS12925	COG1645	bacterial-type flagellum-dependent swarming motility
E1A98_RS12935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E1A98_RS12940	COG2976	Protein conserved in bacteria
E1A98_RS12970	COG4953	penicillin-binding protein 1C
E1A98_RS12975	COG2373	Large extracellular alpha-helical protein
E1A98_RS12980	COG2897	thiosulfate sulfurtransferase activity
E1A98_RS12995	COG2975	iron-sulfur cluster assembly
E1A98_RS13000	COG0633	Ferredoxin
E1A98_RS13020	COG0822	iron-sulfur transferase activity
E1A98_RS13040	COG0483	inositol monophosphate 1-phosphatase activity
E1A98_RS13045	COG1073	alpha beta
E1A98_RS13050	COG3711	transcriptional antiterminator
E1A98_RS13055	COG2814	Major facilitator Superfamily
E1A98_RS13060	COG0583	DNA-binding transcription factor activity
E1A98_RS13065	COG4638	Rieske (2fe-2S)
E1A98_RS13090	COG2259	Doxx family
E1A98_RS13095	COG2017	converts alpha-aldose to the beta-anomer
E1A98_RS13100	COG1063	alcohol dehydrogenase
E1A98_RS13105	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS13110	COG1129	ABC transporter
E1A98_RS13115	COG1879	ABC-type sugar transport system periplasmic component
E1A98_RS13120	COG0457	Tetratricopeptide repeat
E1A98_RS13125	COG1940	carbohydrate kinase activity
E1A98_RS13135	COG1017	nitric oxide dioxygenase activity
E1A98_RS13135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E1A98_RS13140	COG0347	Belongs to the P(II) protein family
E1A98_RS13145	COG2204	response regulator
E1A98_RS13150	COG3170	Tfp pilus assembly protein FimV
E1A98_RS13155	COG2205	protein histidine kinase activity
E1A98_RS13160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E1A98_RS13160	COG0047	phosphoribosylformylglycinamidine synthase activity
E1A98_RS13170	COG0590	tRNA wobble adenosine to inosine editing
E1A98_RS13175	COG0560	Phosphoserine phosphatase
E1A98_RS13180	COG1737	Transcriptional regulator
E1A98_RS13185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS13200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
E1A98_RS13220	COG0681	Belongs to the peptidase S26 family
E1A98_RS13230	COG3086	response to oxidative stress
E1A98_RS13235	COG3026	antisigma factor binding
E1A98_RS13240	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
E1A98_RS13245	COG1595	DNA-templated transcription, initiation
E1A98_RS13255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E1A98_RS13260	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E1A98_RS13265	COG0513	Belongs to the DEAD box helicase family
E1A98_RS13270	COG0583	DNA-binding transcription factor activity
E1A98_RS13290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E1A98_RS13295	COG3118	belongs to the thioredoxin family
E1A98_RS13305	COG1042	CoA-binding domain protein
E1A98_RS13305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A98_RS13305	COG0045	succinate-CoA ligase (ADP-forming) activity
E1A98_RS13310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A98_RS13315	COG5544	Lipoprotein
E1A98_RS13320	COG0477	Major facilitator Superfamily
E1A98_RS13345	COG0542	response to heat
E1A98_RS13355	COG0564	pseudouridine synthase activity
E1A98_RS13360	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E1A98_RS13365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E1A98_RS13375	COG0077	Prephenate dehydratase
E1A98_RS13375	COG1605	Chorismate mutase
E1A98_RS13380	COG1605	Chorismate mutase
E1A98_RS13380	COG0287	Prephenate dehydrogenase
E1A98_RS13385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E1A98_RS13400	COG2199	diguanylate cyclase activity
E1A98_RS13405	COG2885	chlorophyll binding
E1A98_RS13430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E1A98_RS13435	COG4137	Cytochrome C assembly protein
E1A98_RS13440	COG4536	flavin adenine dinucleotide binding
E1A98_RS13460	COG0497	DNA recombination
E1A98_RS13465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E1A98_RS13470	COG2914	Belongs to the UPF0125 (RnfH) family
E1A98_RS13475	COG2867	negative regulation of translational initiation
E1A98_RS13490	COG0582	viral genome integration into host DNA
E1A98_RS13500	COG3311	Transcriptional regulator
E1A98_RS13505	COG4983	Phage plasmid primase, P4 family domain protein
E1A98_RS13515	COG1204	response to ionizing radiation
E1A98_RS13525	COG1479	Protein of unknown function DUF262
E1A98_RS13540	COG3596	GTP binding
E1A98_RS13550	COG2378	regulation of single-species biofilm formation
E1A98_RS13595	COG2003	Belongs to the UPF0758 family
E1A98_RS13615	COG3468	outer membrane autotransporter barrel domain protein
E1A98_RS13655	COG0579	oxidoreductase
E1A98_RS13660	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS13665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E1A98_RS13670	COG1113	amino acid transport
E1A98_RS13675	COG1802	Transcriptional regulator
E1A98_RS13680	COG1652	LysM domain
E1A98_RS13685	COG0401	homolog of Blt101
E1A98_RS13690	COG0640	Transcriptional regulator
E1A98_RS13695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A98_RS13700	COG2916	Histone family protein nucleoid-structuring protein H-NS
E1A98_RS13715	COG4575	ribosome binding
E1A98_RS13720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E1A98_RS13725	COG1780	Probably involved in ribonucleotide reductase function
E1A98_RS13730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E1A98_RS13735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E1A98_RS13745	COG4175	Glycine betaine
E1A98_RS13750	COG4176	ABC-type proline glycine betaine transport system permease component
E1A98_RS13755	COG2113	Glycine betaine
E1A98_RS13765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E1A98_RS13775	COG1846	Transcriptional regulator
E1A98_RS13780	COG1566	PFAM secretion protein HlyD family protein
E1A98_RS13785	COG2814	Major facilitator Superfamily
E1A98_RS13800	COG1238	metal cluster binding
E1A98_RS13805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1A98_RS13855	COG1546	Belongs to the CinA family
E1A98_RS13860	COG2951	lytic endotransglycosylase activity
E1A98_RS13865	COG3730	PTS system glucitol sorbitol-specific
E1A98_RS13870	COG3732	PTS system glucitol sorbitol-specific
E1A98_RS13875	COG3731	PTS system glucitol sorbitol-specific IIA component
E1A98_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS13885	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS13890	COG1349	DNA-binding transcription factor activity
E1A98_RS13895	COG0517	IMP dehydrogenase activity
E1A98_RS13895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E1A98_RS13915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E1A98_RS13920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS13925	COG1609	Transcriptional regulator
E1A98_RS13930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS13930	COG1263	PTS System
E1A98_RS13935	COG2723	6-phospho-beta-galactosidase activity
E1A98_RS13940	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E1A98_RS13950	COG3260	NADH ubiquinone oxidoreductase 20
E1A98_RS13955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A98_RS13960	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E1A98_RS13960	COG3261	NADH dehydrogenase
E1A98_RS13965	COG0650	Formate hydrogenlyase subunit 4
E1A98_RS13970	COG0651	ATP synthesis coupled electron transport
E1A98_RS13975	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS13990	COG0375	protein maturation
E1A98_RS13995	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E1A98_RS14000	COG0298	carbon dioxide binding
E1A98_RS14005	COG0409	Hydrogenase expression formation protein
E1A98_RS14010	COG0309	Hydrogenase expression formation protein (HypE)
E1A98_RS14015	COG3604	Transcriptional regulator
E1A98_RS14030	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E1A98_RS14035	COG1349	DNA-binding transcription factor activity
E1A98_RS14040	COG2084	Dehydrogenase
E1A98_RS14045	COG3395	kinase activity
E1A98_RS14050	COG0235	Class ii aldolase
E1A98_RS14055	COG3622	Belongs to the hyi family
E1A98_RS14060	COG2610	gluconate transmembrane transporter activity
E1A98_RS14065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E1A98_RS14070	COG4942	peptidase
E1A98_RS14070	COG1388	LysM domain
E1A98_RS14125	COG2234	aminopeptidase activity
E1A98_RS14130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E1A98_RS14135	COG1518	maintenance of DNA repeat elements
E1A98_RS14150	COG1857	crispr-associated protein
E1A98_RS14165	COG1203	CRISPR-associated helicase, Cas3
E1A98_RS14185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
E1A98_RS14190	COG0720	synthase
E1A98_RS14195	COG0644	oxidoreductase
E1A98_RS14200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E1A98_RS14205	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E1A98_RS14210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E1A98_RS14215	COG2086	electron transfer activity
E1A98_RS14220	COG0477	Major facilitator Superfamily
E1A98_RS14225	COG0277	FAD linked oxidase domain protein
E1A98_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS14235	COG2223	nitrite transmembrane transporter activity
E1A98_RS14240	COG1070	Carbohydrate kinase
E1A98_RS14245	COG0602	queuosine metabolic process
E1A98_RS14255	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
E1A98_RS14270	COG3956	TIGRFAM MazG family protein
E1A98_RS14275	COG2337	Toxic component of a toxin-antitoxin (TA) module
E1A98_RS14280	COG2336	PFAM SpoVT AbrB
E1A98_RS14285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E1A98_RS14290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E1A98_RS14295	COG4999	Histidine kinase
E1A98_RS14295	COG3437	response regulator, receiver
E1A98_RS14295	COG2205	protein histidine kinase activity
E1A98_RS14295	COG3850	Histidine kinase
E1A98_RS14300	COG4948	Mandelate Racemase Muconate Lactonizing
E1A98_RS14305	COG4948	Mandelate Racemase Muconate Lactonizing
E1A98_RS14310	COG2271	Major facilitator Superfamily
E1A98_RS14315	COG0716	FMN binding
E1A98_RS14320	COG0564	pseudouridine synthase activity
E1A98_RS14325	COG3098	single-species biofilm formation
E1A98_RS14340	COG1611	Belongs to the LOG family
E1A98_RS14345	COG0814	amino acid
E1A98_RS14350	COG1760	l-serine dehydratase
E1A98_RS14360	COG1454	alcohol dehydrogenase
E1A98_RS14365	COG0235	Class ii aldolase
E1A98_RS14370	COG0738	Major facilitator superfamily
E1A98_RS14380	COG1070	Carbohydrate kinase
E1A98_RS14390	COG1349	DNA-binding transcription factor activity
E1A98_RS14400	COG2363	Small membrane protein
E1A98_RS14405	COG0583	DNA-binding transcription factor activity
E1A98_RS14415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E1A98_RS14420	COG2166	iron-sulfur cluster assembly
E1A98_RS14425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E1A98_RS14430	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E1A98_RS14450	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A98_RS14455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
E1A98_RS14455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E1A98_RS14460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E1A98_RS14465	COG1074	ATP-dependent DNA helicase activity
E1A98_RS14470	COG1025	Belongs to the peptidase M16 family
E1A98_RS14475	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E1A98_RS14480	COG4967	type IV pilus modification protein PilV
E1A98_RS14490	COG4795	General secretion pathway protein
E1A98_RS14495	COG2165	general secretion pathway protein
E1A98_RS14510	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
E1A98_RS14530	COG0861	Integral membrane protein TerC family
E1A98_RS14540	COG0667	Aldo Keto reductase
E1A98_RS14555	COG1609	Transcriptional regulator
E1A98_RS14560	COG0019	diaminopimelate decarboxylase activity
E1A98_RS14565	COG0583	DNA-binding transcription factor activity
E1A98_RS14570	COG1794	racemase activity, acting on amino acids and derivatives
E1A98_RS14575	COG2814	Major facilitator Superfamily
E1A98_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS14590	COG0183	Belongs to the thiolase family
E1A98_RS14595	COG0814	amino acid
E1A98_RS14600	COG2771	luxR family
E1A98_RS14605	COG3710	Transcriptional regulator
E1A98_RS14630	COG0457	Tetratricopeptide repeat
E1A98_RS14635	COG0457	Tetratricopeptide repeat
E1A98_RS14635	COG3710	Transcriptional regulator
E1A98_RS14685	COG4942	peptidase
E1A98_RS14690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E1A98_RS14695	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E1A98_RS14700	COG2080	2 iron, 2 sulfur cluster binding
E1A98_RS14710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E1A98_RS14715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E1A98_RS14720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E1A98_RS14730	COG0549	Belongs to the carbamate kinase family
E1A98_RS14735	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
E1A98_RS14735	COG3608	succinylglutamate desuccinylase aspartoacylase
E1A98_RS14740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E1A98_RS14745	COG2068	MobA-Related Protein
E1A98_RS14750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS14750	COG0493	'glutamate synthase
E1A98_RS14755	COG0402	S-adenosylhomocysteine deaminase activity
E1A98_RS14760	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
E1A98_RS14765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
E1A98_RS14765	COG2080	2 iron, 2 sulfur cluster binding
E1A98_RS14770	COG2233	PERMEase
E1A98_RS14775	COG0402	S-adenosylhomocysteine deaminase activity
E1A98_RS14780	COG2252	PERMEase
E1A98_RS14785	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS14795	COG2233	PERMEase
E1A98_RS14815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E1A98_RS14825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E1A98_RS14830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E1A98_RS14835	COG4974	Belongs to the 'phage' integrase family
E1A98_RS14840	COG0716	FMN binding
E1A98_RS14850	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
E1A98_RS14860	COG1272	protein, Hemolysin III
E1A98_RS14870	COG2723	6-phospho-beta-galactosidase activity
E1A98_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS14900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E1A98_RS14905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E1A98_RS14910	COG0006	proline dipeptidase activity
E1A98_RS14930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E1A98_RS14940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E1A98_RS14960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E1A98_RS14960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E1A98_RS14965	COG1703	isobutyryl-CoA mutase activity
E1A98_RS14970	COG1024	Enoyl-CoA hydratase
E1A98_RS14975	COG0427	acetyl-CoA hydrolase
E1A98_RS14980	COG0583	DNA-binding transcription factor activity
E1A98_RS14985	COG2968	Membrane
E1A98_RS14990	COG1279	arginine transmembrane transporter activity
E1A98_RS14995	COG0668	transmembrane transport
E1A98_RS15000	COG0191	fructose-bisphosphate aldolase activity
E1A98_RS15015	COG1072	(Pantothenic acid kinase))
E1A98_RS15020	COG3722	fumarate hydratase activity
E1A98_RS15025	COG1494	fructose-1,6-bisphosphatase
E1A98_RS15030	COG1063	alcohol dehydrogenase
E1A98_RS15035	COG2213	PTS system mannitol-specific
E1A98_RS15040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS15045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E1A98_RS15050	COG0501	Belongs to the peptidase M48B family
E1A98_RS15060	COG1166	arginine decarboxylase activity
E1A98_RS15085	COG2814	Major facilitator Superfamily
E1A98_RS15095	COG2356	endonuclease I
E1A98_RS15100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E1A98_RS15105	COG0189	ligase activity
E1A98_RS15120	COG2805	Type II/IV secretion system protein
E1A98_RS15125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E1A98_RS15130	COG0762	integral membrane protein
E1A98_RS15140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
E1A98_RS15145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E1A98_RS15155	COG0252	asparaginase activity
E1A98_RS15165	COG3171	Protein conserved in bacteria
E1A98_RS15175	COG1194	a g-specific adenine glycosylase
E1A98_RS15190	COG2211	Major facilitator Superfamily
E1A98_RS15195	COG1982	Orn Lys Arg decarboxylase major
E1A98_RS15200	COG1811	Na channel or pump
E1A98_RS15210	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
E1A98_RS15220	COG3031	protein transport across the cell outer membrane
E1A98_RS15230	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E1A98_RS15235	COG3064	Membrane
E1A98_RS15240	COG1620	l-lactate permease
E1A98_RS15245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E1A98_RS15250	COG3193	protein, possibly involved in utilization of glycolate and propanediol
E1A98_RS15255	COG0247	lactate metabolic process
E1A98_RS15260	COG0277	FAD linked oxidase domain protein
E1A98_RS15265	COG0277	FAD linked oxidase domain protein
E1A98_RS15270	COG2186	Transcriptional regulator
E1A98_RS15275	COG0456	acetyltransferase
E1A98_RS15280	COG3039	Transposase
E1A98_RS15285	COG2244	polysaccharide biosynthetic process
E1A98_RS15290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E1A98_RS15295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E1A98_RS15300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E1A98_RS15305	COG0306	phosphate transporter
E1A98_RS15310	COG0754	glutathionylspermidine amidase activity
E1A98_RS15315	COG0625	glutathione transferase activity
E1A98_RS15320	COG0298	carbon dioxide binding
E1A98_RS15325	COG0375	protein maturation
E1A98_RS15330	COG1773	rubredoxin
E1A98_RS15335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E1A98_RS15340	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E1A98_RS15345	COG5557	Pfam Polysulphide reductase, NrfD
E1A98_RS15350	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS15355	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E1A98_RS15370	COG0667	Aldo Keto reductase
E1A98_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS15385	COG0848	biopolymer transport protein
E1A98_RS15390	COG0811	peptide transport
E1A98_RS15395	COG0626	cystathionine gamma-synthase activity
E1A98_RS15400	COG0586	Pfam SNARE associated Golgi protein
E1A98_RS15405	COG2207	Transcriptional regulator
E1A98_RS15410	COG1979	alcohol dehydrogenase
E1A98_RS15415	COG0656	L-ascorbic acid biosynthetic process
E1A98_RS15425	COG4238	major outer membrane lipoprotein
E1A98_RS15430	COG1032	radical SAM domain protein
E1A98_RS15435	COG2132	Multicopper oxidase
E1A98_RS15440	COG0204	Acyl-transferase
E1A98_RS15445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E1A98_RS15450	COG4166	transmembrane transport
E1A98_RS15455	COG2944	sequence-specific DNA binding
E1A98_RS15465	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E1A98_RS15470	COG3111	PFAM Bacterial OB fold (BOF) protein
E1A98_RS15475	COG0745	RESPONSE REGULATOR receiver
E1A98_RS15480	COG0642	Histidine kinase
E1A98_RS15490	COG2249	NAD(P)H dehydrogenase (quinone) activity
E1A98_RS15495	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E1A98_RS15500	COG0187	DNA topoisomerase II activity
E1A98_RS15505	COG3150	esterase
E1A98_RS15510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E1A98_RS15515	COG3151	Protein conserved in bacteria
E1A98_RS15520	COG0494	nUDIX hydrolase
E1A98_RS15525	COG1538	Outer membrane efflux protein
E1A98_RS15535	COG0754	glutathionylspermidine amidase activity
E1A98_RS15540	COG3384	dioxygenase
E1A98_RS15555	COG2960	long-chain fatty acid transporting porin activity
E1A98_RS15560	COG3539	Fimbrial protein
E1A98_RS15570	COG3188	usher protein
E1A98_RS15575	COG3121	Chaperone
E1A98_RS15580	COG3539	Fimbrial protein
E1A98_RS15590	COG1585	Membrane protein implicated in regulation of membrane protease activity
E1A98_RS15595	COG2268	Band 7 protein
E1A98_RS15620	COG3025	triphosphatase activity
E1A98_RS15625	COG4991	sh3 domain protein
E1A98_RS15635	COG1968	undecaprenyl-diphosphatase activity
E1A98_RS15640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E1A98_RS15650	COG0583	DNA-binding transcription factor activity
E1A98_RS15665	COG0471	metal ion transport
E1A98_RS15680	COG0358	DNA primase activity
E1A98_RS15685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E1A98_RS15700	COG2375	cellular response to nickel ion
E1A98_RS15705	COG1695	Transcriptional regulator
E1A98_RS15710	COG0840	transmembrane signaling receptor activity
E1A98_RS15720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E1A98_RS15725	COG1609	Transcriptional regulator
E1A98_RS15730	COG3250	beta-galactosidase activity
E1A98_RS15735	COG2731	YhcH YjgK YiaL family protein
E1A98_RS15740	COG0531	amino acid
E1A98_RS15750	COG3408	Glycogen debranching enzyme
E1A98_RS15750	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E1A98_RS15755	COG1902	pentaerythritol trinitrate reductase activity
E1A98_RS15755	COG0446	pyridine nucleotide-disulphide oxidoreductase
E1A98_RS15760	COG5499	transcription regulator containing HTH domain
E1A98_RS15765	COG4680	protein conserved in bacteria
E1A98_RS15775	COG1451	nucleotide metabolic process
E1A98_RS15780	COG2949	membrane
E1A98_RS15785	COG0673	inositol 2-dehydrogenase activity
E1A98_RS15790	COG0861	Integral membrane protein TerC family
E1A98_RS15795	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
E1A98_RS15805	COG2721	sulfolactate sulfo-lyase activity
E1A98_RS15815	COG2271	Major facilitator Superfamily
E1A98_RS15820	COG2186	Transcriptional regulator
E1A98_RS15825	COG0586	Pfam SNARE associated Golgi protein
E1A98_RS15835	COG1422	Protein of unknown function (DUF1090)
E1A98_RS15840	COG4575	ribosome binding
E1A98_RS15845	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E1A98_RS15855	COG2259	Doxx family
E1A98_RS15860	COG0435	Glutathione S-transferase
E1A98_RS15865	COG3152	Membrane
E1A98_RS15870	COG3152	Membrane
E1A98_RS15875	COG0583	DNA-binding transcription factor activity
E1A98_RS15880	COG1741	Belongs to the pirin family
E1A98_RS15895	COG0814	amino acid
E1A98_RS15900	COG1760	l-serine dehydratase
E1A98_RS15905	COG0251	oxidation-reduction process
E1A98_RS15910	COG1882	Formate acetyltransferase
E1A98_RS15915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E1A98_RS15925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E1A98_RS15930	COG0583	DNA-binding transcription factor activity
E1A98_RS15955	COG1929	Belongs to the glycerate kinase type-1 family
E1A98_RS15960	COG2084	Dehydrogenase
E1A98_RS15970	COG2271	Major facilitator Superfamily
E1A98_RS15975	COG2721	sulfolactate sulfo-lyase activity
E1A98_RS15980	COG2002	toxin-antitoxin pair type II binding
E1A98_RS15990	COG1349	DNA-binding transcription factor activity
E1A98_RS16000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS16015	COG2222	sugar isomerase
E1A98_RS16025	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS16030	COG3715	PTS system
E1A98_RS16035	COG3716	PTS system mannose fructose sorbose family IID component
E1A98_RS16040	COG0363	glucosamine-6-phosphate deaminase activity
E1A98_RS16045	COG3539	Fimbrial protein
E1A98_RS16050	COG3121	Chaperone
E1A98_RS16055	COG3188	usher protein
E1A98_RS16060	COG3539	Fimbrial protein
E1A98_RS16065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E1A98_RS16070	COG3107	peptidoglycan biosynthetic process
E1A98_RS16080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
E1A98_RS16085	COG2823	Periplasmic or secreted lipoprotein
E1A98_RS16090	COG0701	Predicted permease
E1A98_RS16095	COG0702	epimerase
E1A98_RS16100	COG0693	protein deglycase activity
E1A98_RS16115	COG3153	acetyltransferase
E1A98_RS16135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E1A98_RS16140	COG0814	amino acid
E1A98_RS16145	COG0513	Belongs to the DEAD box helicase family
E1A98_RS16155	COG4785	May be involved in cell division
E1A98_RS16170	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
E1A98_RS16185	COG0195	Participates in both transcription termination and antitermination
E1A98_RS16205	COG2194	sulfuric ester hydrolase activity
E1A98_RS16215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E1A98_RS16225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E1A98_RS16230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E1A98_RS16240	COG1534	Rna-binding protein
E1A98_RS16245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E1A98_RS16250	COG2027	D-alanyl-D-alanine carboxypeptidase
E1A98_RS16260	COG0697	spore germination
E1A98_RS16275	COG0142	geranyltranstransferase activity
E1A98_RS16280	COG3423	Transcriptional regulator
E1A98_RS16290	COG5007	Belongs to the BolA IbaG family
E1A98_RS16295	COG3113	response to antibiotic
E1A98_RS16300	COG2854	intermembrane phospholipid transfer
E1A98_RS16305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E1A98_RS16310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E1A98_RS16315	COG1127	ABC transporter
E1A98_RS16320	COG0530	calcium, potassium:sodium antiporter activity
E1A98_RS16325	COG0517	IMP dehydrogenase activity
E1A98_RS16325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E1A98_RS16330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E1A98_RS16335	COG3117	lipopolysaccharide transmembrane transporter activity
E1A98_RS16340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E1A98_RS16345	COG1137	ATPase activity
E1A98_RS16350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
E1A98_RS16355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E1A98_RS16360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS16370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS16375	COG0515	serine threonine protein kinase
E1A98_RS16385	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E1A98_RS16390	COG0784	Response regulator, receiver
E1A98_RS16390	COG2198	Histidine kinase
E1A98_RS16390	COG5002	protein histidine kinase activity
E1A98_RS16395	COG1242	4 iron, 4 sulfur cluster binding
E1A98_RS16400	COG0070	glutamate synthase
E1A98_RS16400	COG0069	glutamate synthase activity
E1A98_RS16400	COG0067	glutamate synthase
E1A98_RS16405	COG0493	'glutamate synthase
E1A98_RS16410	COG3539	Fimbrial protein
E1A98_RS16415	COG3121	Chaperone
E1A98_RS16420	COG3188	usher protein
E1A98_RS16430	COG3039	Transposase
E1A98_RS16440	COG3539	Fimbrial protein
E1A98_RS16445	COG4804	nuclease activity
E1A98_RS16450	COG2731	YhcH YjgK YiaL family protein
E1A98_RS16480	COG3069	C4-dicarboxylate transmembrane transporter activity
E1A98_RS16485	COG2969	positive regulation of protein catabolic process
E1A98_RS16490	COG0625	glutathione transferase activity
E1A98_RS16505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E1A98_RS16510	COG3105	Protein conserved in bacteria
E1A98_RS16515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E1A98_RS16520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E1A98_RS16540	COG2732	(Barnase) inhibitor
E1A98_RS16545	COG1289	transmembrane transporter activity
E1A98_RS16560	COG0583	DNA-binding transcription factor activity
E1A98_RS16565	COG0312	modulator of DNA gyrase
E1A98_RS16570	COG3164	Protein of unknown function
E1A98_RS16575	COG1530	ribonuclease E activity
E1A98_RS16580	COG0424	maF-like protein
E1A98_RS16585	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E1A98_RS16590	COG1792	Involved in formation and maintenance of cell shape
E1A98_RS16595	COG1077	Cell shape determining protein MreB Mrl
E1A98_RS16605	COG2200	EAL domain
E1A98_RS16605	COG2199	diguanylate cyclase activity
E1A98_RS16610	COG0604	alcohol dehydrogenase
E1A98_RS16615	COG0511	ligase activity, forming carbon-carbon bonds
E1A98_RS16620	COG0439	Biotin carboxylase
E1A98_RS16625	COG3924	membrane
E1A98_RS16630	COG4145	pantothenate transmembrane transporter activity
E1A98_RS16640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E1A98_RS16650	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E1A98_RS16660	COG1309	transcriptional regulator
E1A98_RS16665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E1A98_RS16670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E1A98_RS16685	COG4597	amino acid ABC transporter
E1A98_RS16690	COG0765	amino acid transport
E1A98_RS16695	COG1126	abc transporter atp-binding protein
E1A98_RS16735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E1A98_RS16755	COG0551	DNA topoisomerase type I activity
E1A98_RS16765	COG0758	DNA mediated transformation
E1A98_RS16785	COG0569	domain protein
E1A98_RS16795	COG3036	rescue of stalled ribosome
E1A98_RS16800	COG0789	Transcriptional regulator
E1A98_RS16830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E1A98_RS16840	COG0201	protein transport
E1A98_RS16930	COG0089	rRNA binding
E1A98_RS16955	COG3267	Type II secretory pathway component ExeA
E1A98_RS16955	COG3409	Peptidoglycan-binding domain 1 protein
E1A98_RS16960	COG3031	protein transport across the cell outer membrane
E1A98_RS16965	COG1450	Type ii and iii secretion system protein
E1A98_RS16970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E1A98_RS16975	COG1459	type II secretion system
E1A98_RS16980	COG2165	general secretion pathway protein
E1A98_RS16985	COG2165	general secretion pathway protein
E1A98_RS16990	COG2165	general secretion pathway protein
E1A98_RS16995	COG4795	General secretion pathway protein
E1A98_RS17000	COG3156	type II secretion system protein K
E1A98_RS17005	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
E1A98_RS17010	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
E1A98_RS17015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E1A98_RS17020	COG2193	ferroxidase activity
E1A98_RS17025	COG2906	2 iron, 2 sulfur cluster binding
E1A98_RS17030	COG3979	chitinase
E1A98_RS17070	COG2964	Protein conserved in bacteria
E1A98_RS17075	COG0545	Peptidyl-prolyl cis-trans isomerase
E1A98_RS17085	COG1047	Peptidyl-prolyl cis-trans
E1A98_RS17090	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E1A98_RS17105	COG0488	(ABC) transporter
E1A98_RS17110	COG0429	hydrolase of the alpha beta-hydrolase fold
E1A98_RS17120	COG3954	Phosphoribulokinase
E1A98_RS17125	COG1765	OsmC-like protein
E1A98_RS17130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E1A98_RS17135	COG1289	transmembrane transporter activity
E1A98_RS17140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E1A98_RS17145	COG0512	Glutamine amidotransferase of anthranilate synthase
E1A98_RS17150	COG2184	nucleotidyltransferase activity
E1A98_RS17160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E1A98_RS17170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E1A98_RS17175	COG2146	nitrite reductase [NAD(P)H] activity
E1A98_RS17180	COG2116	formate transmembrane transporter activity
E1A98_RS17195	COG0531	amino acid
E1A98_RS17200	COG2222	sugar isomerase
E1A98_RS17205	COG1082	Xylose isomerase domain protein TIM barrel
E1A98_RS17210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS17215	COG2188	Transcriptional regulator
E1A98_RS17220	COG0626	cystathionine gamma-synthase activity
E1A98_RS17235	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E1A98_RS17240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
E1A98_RS17245	COG3457	Alanine racemase
E1A98_RS17255	COG2188	Transcriptional regulator
E1A98_RS17265	COG0180	Tryptophanyl-tRNA synthetase
E1A98_RS17270	COG0546	phosphoglycolate phosphatase activity
E1A98_RS17275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E1A98_RS17280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E1A98_RS17285	COG3266	domain, Protein
E1A98_RS17300	COG4796	Type ii and iii secretion system protein
E1A98_RS17315	COG3166	PFAM Fimbrial assembly family protein
E1A98_RS17320	COG4972	Pilus assembly protein
E1A98_RS17325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E1A98_RS17330	COG0494	nUDIX hydrolase
E1A98_RS17340	COG1011	Hydrolase
E1A98_RS17345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E1A98_RS17355	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E1A98_RS17365	COG2205	protein histidine kinase activity
E1A98_RS17370	COG0745	RESPONSE REGULATOR receiver
E1A98_RS17375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E1A98_RS17380	COG2183	response to ionizing radiation
E1A98_RS17385	COG1918	ferrous iron import across plasma membrane
E1A98_RS17390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E1A98_RS17400	COG5464	transposase or invertase
E1A98_RS17410	COG1040	competence protein
E1A98_RS17420	COG2610	gluconate transmembrane transporter activity
E1A98_RS17425	COG1640	4-alpha-glucanotransferase
E1A98_RS17430	COG0058	SHG alpha-glucan phosphorylase activity
E1A98_RS17445	COG1690	Belongs to the RtcB family
E1A98_RS17450	COG4650	regulator
E1A98_RS17455	COG1349	DNA-binding transcription factor activity
E1A98_RS17470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E1A98_RS17480	COG0058	SHG alpha-glucan phosphorylase activity
E1A98_RS17505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E1A98_RS17510	COG2095	MarC family integral membrane protein
E1A98_RS17515	COG2610	gluconate transmembrane transporter activity
E1A98_RS17520	COG3265	gluconokinase activity
E1A98_RS17525	COG1609	Transcriptional regulator
E1A98_RS17530	COG1741	Belongs to the pirin family
E1A98_RS17535	COG0673	inositol 2-dehydrogenase activity
E1A98_RS17540	COG1247	-acetyltransferase
E1A98_RS17545	COG3157	Type VI secretion system effector, Hcp
E1A98_RS17570	COG0405	Gamma-glutamyltransferase
E1A98_RS17580	COG0584	glycerophosphoryl diester phosphodiesterase
E1A98_RS17585	COG3842	ATPase activity
E1A98_RS17590	COG0395	ABC-type sugar transport system, permease component
E1A98_RS17595	COG1175	transmembrane transport
E1A98_RS17600	COG1653	transport
E1A98_RS17605	COG0410	ABC transporter
E1A98_RS17610	COG0411	ABC transporter
E1A98_RS17615	COG4177	L-phenylalanine transmembrane transporter activity
E1A98_RS17620	COG0559	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS17625	COG0683	leucine binding
E1A98_RS17630	COG0456	acetyltransferase
E1A98_RS17635	COG0683	leucine binding
E1A98_RS17640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E1A98_RS17645	COG2177	Part of the ABC transporter FtsEX involved in
E1A98_RS17650	COG2884	Cell division ATP-binding protein ftsE
E1A98_RS17655	COG0552	protein localization to endoplasmic reticulum
E1A98_RS17660	COG0742	ribosomal rna small subunit methyltransferase
E1A98_RS17665	COG3776	membrane
E1A98_RS17675	COG3714	YhhN family
E1A98_RS17680	COG2217	Heavy metal translocating P-type atpase
E1A98_RS17690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E1A98_RS17700	COG0477	Major facilitator Superfamily
E1A98_RS17705	COG0628	permease
E1A98_RS17710	COG2091	lysine biosynthetic process via aminoadipic acid
E1A98_RS17715	COG0747	negative chemotaxis
E1A98_RS17720	COG0601	transmembrane transport
E1A98_RS17725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1A98_RS17730	COG0444	Belongs to the ABC transporter superfamily
E1A98_RS17735	COG1124	(ABC) transporter
E1A98_RS17745	COG3209	COG3209 Rhs family protein
E1A98_RS17760	COG5433	transposase activity
E1A98_RS17765	COG0842	Transport permease protein
E1A98_RS17770	COG0842	Transport permease protein
E1A98_RS17770	COG1129	ABC transporter
E1A98_RS17775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E1A98_RS17795	COG2081	HI0933 family
E1A98_RS17800	COG0306	phosphate transporter
E1A98_RS17810	COG0589	response to stress
E1A98_RS17815	COG3104	oligopeptide transport
E1A98_RS17820	COG0742	ribosomal rna small subunit methyltransferase
E1A98_RS17825	COG0339	signal peptide processing
E1A98_RS17830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E1A98_RS17835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E1A98_RS17845	COG0640	Transcriptional regulator
E1A98_RS17850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E1A98_RS17855	COG1393	Belongs to the ArsC family
E1A98_RS17865	COG3039	Transposase
E1A98_RS17875	COG3065	identical protein binding
E1A98_RS17880	COG2197	response regulator
E1A98_RS17885	COG1285	pathogenesis
E1A98_RS17900	COG3247	response to pH
E1A98_RS17905	COG2771	luxR family
E1A98_RS17915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E1A98_RS17920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E1A98_RS17925	COG2207	Transcriptional regulator
E1A98_RS17930	COG2207	Transcriptional regulator
E1A98_RS17935	COG0076	glutamate decarboxylase activity
E1A98_RS17940	COG1858	cytochrome C peroxidase
E1A98_RS17945	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E1A98_RS17950	COG2197	response regulator
E1A98_RS17955	COG0583	DNA-binding transcription factor activity
E1A98_RS17960	COG1295	ribonuclease BN
E1A98_RS17965	COG0477	Major facilitator Superfamily
E1A98_RS17970	COG2982	Protein involved in outer membrane biogenesis
E1A98_RS17975	COG2200	EAL domain
E1A98_RS17980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS17985	COG0612	Peptidase, M16
E1A98_RS17995	COG2199	diguanylate cyclase activity
E1A98_RS17995	COG2200	EAL domain
E1A98_RS18000	COG3118	belongs to the thioredoxin family
E1A98_RS18000	COG0457	Tetratricopeptide repeat
E1A98_RS18005	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
E1A98_RS18010	COG1215	transferase activity, transferring glycosyl groups
E1A98_RS18015	COG1215	transferase activity, transferring glycosyl groups
E1A98_RS18040	COG2194	sulfuric ester hydrolase activity
E1A98_RS18050	COG0814	amino acid
E1A98_RS18055	COG4608	Belongs to the ABC transporter superfamily
E1A98_RS18060	COG0444	Belongs to the ABC transporter superfamily
E1A98_RS18065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1A98_RS18070	COG0601	transmembrane transport
E1A98_RS18080	COG0747	negative chemotaxis
E1A98_RS18095	COG2194	sulfuric ester hydrolase activity
E1A98_RS18100	COG2223	nitrite transmembrane transporter activity
E1A98_RS18105	COG5571	outer membrane autotransporter
E1A98_RS18110	COG2818	Glycosylase
E1A98_RS18115	COG0456	acetyltransferase
E1A98_RS18120	COG0243	molybdopterin cofactor binding
E1A98_RS18125	COG2885	chlorophyll binding
E1A98_RS18140	COG2944	sequence-specific DNA binding
E1A98_RS18145	COG1278	Cold shock
E1A98_RS18165	COG0752	glycyl-tRNA synthetase alpha subunit
E1A98_RS18175	COG3274	enterobacterial common antigen metabolic process
E1A98_RS18180	COG4682	membrane
E1A98_RS18185	COG4682	membrane
E1A98_RS18190	COG1070	Carbohydrate kinase
E1A98_RS18200	COG4213	ABC transporter substrate-binding protein
E1A98_RS18205	COG1129	ABC transporter
E1A98_RS18210	COG4214	carbohydrate transport
E1A98_RS18215	COG1609	Transcriptional regulator
E1A98_RS18215	COG2207	Transcriptional regulator
E1A98_RS18220	COG2992	FlgJ-related protein
E1A98_RS18225	COG0366	Alpha amylase catalytic
E1A98_RS18230	COG3977	Valine--pyruvate aminotransferase
E1A98_RS18235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E1A98_RS18240	COG1414	Transcriptional regulator
E1A98_RS18250	COG2731	YhcH YjgK YiaL family protein
E1A98_RS18255	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
E1A98_RS18260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
E1A98_RS18265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E1A98_RS18270	COG1070	Carbohydrate kinase
E1A98_RS18275	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E1A98_RS18280	COG3623	hexulose-6-phosphate isomerase
E1A98_RS18285	COG0235	Class ii aldolase
E1A98_RS18295	COG3713	MltA-interacting MipA family protein
E1A98_RS18300	COG0583	DNA-binding transcription factor activity
E1A98_RS18305	COG1566	PFAM secretion protein HlyD family protein
E1A98_RS18320	COG1012	belongs to the aldehyde dehydrogenase family
E1A98_RS18325	COG1454	alcohol dehydrogenase
E1A98_RS18330	COG3276	selenocysteine insertion sequence binding
E1A98_RS18340	COG0625	glutathione transferase activity
E1A98_RS18345	COG3209	COG3209 Rhs family protein
E1A98_RS18360	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E1A98_RS18380	COG1566	PFAM secretion protein HlyD family protein
E1A98_RS18390	COG2213	PTS system mannitol-specific
E1A98_RS18390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS18400	COG3722	fumarate hydratase activity
E1A98_RS18415	COG1620	l-lactate permease
E1A98_RS18420	COG2186	Transcriptional regulator
E1A98_RS18430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E1A98_RS18435	COG1045	serine acetyltransferase
E1A98_RS18450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E1A98_RS18455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A98_RS18465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
E1A98_RS18470	COG4942	peptidase
E1A98_RS18475	COG2861	carbohydrate metabolic process
E1A98_RS18480	COG1216	Glycosyl transferase, family 2
E1A98_RS18490	COG0156	8-amino-7-oxononanoate synthase activity
E1A98_RS18505	COG0859	PFAM glycosyl transferase family 9
E1A98_RS18510	COG0859	PFAM glycosyl transferase family 9
E1A98_RS18515	COG3307	-O-antigen
E1A98_RS18520	COG0859	PFAM glycosyl transferase family 9
E1A98_RS18530	COG3642	lipopolysaccharide core region biosynthetic process
E1A98_RS18535	COG1442	glycosyl transferase family 8
E1A98_RS18540	COG1442	glycosyl transferase family 8
E1A98_RS18545	COG0438	transferase activity, transferring glycosyl groups
E1A98_RS18550	COG0438	transferase activity, transferring glycosyl groups
E1A98_RS18550	COG4641	Protein conserved in bacteria
E1A98_RS18555	COG0515	serine threonine protein kinase
E1A98_RS18560	COG0438	transferase activity, transferring glycosyl groups
E1A98_RS18565	COG0859	PFAM glycosyl transferase family 9
E1A98_RS18570	COG1519	Transferase
E1A98_RS18600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E1A98_RS18625	COG1561	YicC-like family, N-terminal region
E1A98_RS18630	COG3645	SOS response
E1A98_RS18635	COG2860	membrane
E1A98_RS18655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E1A98_RS18660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E1A98_RS18665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E1A98_RS18670	COG0786	glutamate:sodium symporter activity
E1A98_RS18675	COG2233	PERMEase
E1A98_RS18680	COG2982	Protein involved in outer membrane biogenesis
E1A98_RS18685	COG1501	Belongs to the glycosyl hydrolase 31 family
E1A98_RS18690	COG2211	Major facilitator Superfamily
E1A98_RS18705	COG2814	Major facilitator Superfamily
E1A98_RS18710	COG0697	spore germination
E1A98_RS18715	COG1464	Belongs to the NlpA lipoprotein family
E1A98_RS18735	COG2252	PERMEase
E1A98_RS18745	COG2271	Major facilitator Superfamily
E1A98_RS18750	COG2271	Major facilitator Superfamily
E1A98_RS18755	COG3851	Histidine kinase
E1A98_RS18760	COG2197	response regulator
E1A98_RS18765	COG0440	acetolactate synthase activity
E1A98_RS18770	COG0028	Belongs to the TPP enzyme family
E1A98_RS18785	COG2814	Major facilitator Superfamily
E1A98_RS18790	COG0641	radical SAM
E1A98_RS18800	COG2149	membrane
E1A98_RS18810	COG3119	arylsulfatase activity
E1A98_RS18815	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E1A98_RS18820	COG2207	Transcriptional regulator
E1A98_RS18835	COG2188	Transcriptional regulator
E1A98_RS18855	COG5645	(Lipo)protein
E1A98_RS18860	COG0823	Involved in the tonB-independent uptake of proteins
E1A98_RS18865	COG0644	oxidoreductase
E1A98_RS18870	COG2271	Major facilitator Superfamily
E1A98_RS18880	COG0800	Aldolase
E1A98_RS18885	COG3734	2-keto-3-deoxy-galactonokinase
E1A98_RS18890	COG2186	Transcriptional regulator
E1A98_RS18900	COG0561	phosphatase activity
E1A98_RS18905	COG3753	Protein conserved in bacteria
E1A98_RS18910	COG0187	DNA topoisomerase II activity
E1A98_RS18920	COG0592	DNA-directed DNA polymerase activity
E1A98_RS18970	COG0814	amino acid
E1A98_RS18985	COG2091	lysine biosynthetic process via aminoadipic acid
E1A98_RS18990	COG0431	NADPH-dependent FMN reductase
E1A98_RS18995	COG2252	PERMEase
E1A98_RS19000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1A98_RS19010	COG3196	Protein conserved in bacteria
E1A98_RS19015	COG0363	glucosamine-6-phosphate deaminase activity
E1A98_RS19020	COG2382	esterase
E1A98_RS19030	COG2723	6-phospho-beta-galactosidase activity
E1A98_RS19035	COG2190	(PTS) system
E1A98_RS19035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS19035	COG1263	PTS System
E1A98_RS19040	COG3711	transcriptional antiterminator
E1A98_RS19045	COG0704	Plays a role in the regulation of phosphate uptake
E1A98_RS19050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E1A98_RS19055	COG0581	inorganic phosphate transmembrane transporter activity
E1A98_RS19060	COG0573	inorganic phosphate transmembrane transporter activity
E1A98_RS19065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E1A98_RS19070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E1A98_RS19120	COG3312	ion transport
E1A98_RS19135	COG0716	FMN binding
E1A98_RS19140	COG1522	sequence-specific DNA binding
E1A98_RS19150	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E1A98_RS19165	COG1869	D-ribose catabolic process
E1A98_RS19175	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS19180	COG1879	ABC-type sugar transport system periplasmic component
E1A98_RS19185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS19190	COG1609	Transcriptional regulator
E1A98_RS19195	COG0477	Major facilitator Superfamily
E1A98_RS19200	COG2186	Transcriptional regulator
E1A98_RS19240	COG3085	chromosome segregation
E1A98_RS19245	COG0606	chelatase, subunit chli
E1A98_RS19265	COG3978	acetolactate synthase activity
E1A98_RS19270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E1A98_RS19280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E1A98_RS19285	COG0583	DNA-binding transcription factor activity
E1A98_RS19295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E1A98_RS19305	COG0210	DNA helicase
E1A98_RS19310	COG0248	Ppx GppA phosphatase
E1A98_RS19320	COG3118	belongs to the thioredoxin family
E1A98_RS19330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E1A98_RS19335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E1A98_RS19340	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E1A98_RS19345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E1A98_RS19350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E1A98_RS19355	COG1088	dTDP-glucose 4,6-dehydratase activity
E1A98_RS19360	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E1A98_RS19365	COG0456	acetyltransferase
E1A98_RS19370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E1A98_RS19375	COG2244	polysaccharide biosynthetic process
E1A98_RS19395	COG1113	amino acid transport
E1A98_RS19420	COG0641	radical SAM
E1A98_RS19425	COG3119	arylsulfatase activity
E1A98_RS19430	COG3071	HemY protein
E1A98_RS19435	COG2959	enzyme of heme biosynthesis
E1A98_RS19440	COG1587	Uroporphyrinogen-III synthase
E1A98_RS19450	COG3072	Adenylate cyclase
E1A98_RS19465	COG5567	small periplasmic lipoprotein
E1A98_RS19475	COG3159	Protein conserved in bacteria
E1A98_RS19485	COG1011	Hydrolase
E1A98_RS19490	COG0210	DNA helicase
E1A98_RS19495	COG3698	Phosphodiester glycosidase
E1A98_RS19500	COG0598	Magnesium transport protein CorA
E1A98_RS19515	COG2962	Rard protein
E1A98_RS19520	COG2050	protein possibly involved in aromatic compounds catabolism
E1A98_RS19525	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
E1A98_RS19530	COG0514	ATP-dependent DNA helicase (RecQ)
E1A98_RS19535	COG1280	lysine exporter protein (LysE YggA)
E1A98_RS19540	COG1280	lysine exporter protein (LysE YggA)
E1A98_RS19545	COG2267	carboxylic ester hydrolase activity
E1A98_RS19550	COG0561	phosphatase activity
E1A98_RS19560	COG0583	DNA-binding transcription factor activity
E1A98_RS19570	COG0412	Dienelactone hydrolase
E1A98_RS19575	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
E1A98_RS19580	COG1322	Protein conserved in bacteria
E1A98_RS19590	COG3165	ubiquinone biosynthetic process from chorismate
E1A98_RS19600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E1A98_RS19605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E1A98_RS19610	COG0805	protein transport
E1A98_RS19615	COG0084	hydrolase, TatD family'
E1A98_RS19620	COG0250	Participates in transcription elongation, termination and antitermination
E1A98_RS19625	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E1A98_RS19630	COG0543	2 iron, 2 sulfur cluster binding
E1A98_RS19635	COG0183	Belongs to the thiolase family
E1A98_RS19650	COG1739	Uncharacterized protein family UPF0029
E1A98_RS19655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E1A98_RS19660	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
E1A98_RS19690	COG1763	Mo-molybdopterin cofactor biosynthetic process
E1A98_RS19695	COG0746	molybdenum cofactor guanylyltransferase activity
E1A98_RS19700	COG3084	Protein conserved in bacteria
E1A98_RS19705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
E1A98_RS19710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E1A98_RS19715	COG5339	Protein conserved in bacteria
E1A98_RS19720	COG0204	Acyl-transferase
E1A98_RS19730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1A98_RS19730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1A98_RS19745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E1A98_RS19755	COG2204	response regulator
E1A98_RS19760	COG3852	Histidine kinase
E1A98_RS19765	COG0174	glutamine synthetase
E1A98_RS19775	COG2188	Transcriptional regulator
E1A98_RS19780	COG1082	Xylose isomerase domain protein TIM barrel
E1A98_RS19785	COG2271	Major facilitator Superfamily
E1A98_RS19790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E1A98_RS19795	COG2211	Major facilitator Superfamily
E1A98_RS19800	COG2211	Major facilitator Superfamily
E1A98_RS19805	COG1501	Belongs to the glycosyl hydrolase 31 family
E1A98_RS19810	COG2017	converts alpha-aldose to the beta-anomer
E1A98_RS19815	COG2942	2-epimerase
E1A98_RS19820	COG3684	Belongs to the aldolase LacD family
E1A98_RS19825	COG2084	Dehydrogenase
E1A98_RS19830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A98_RS19835	COG1349	DNA-binding transcription factor activity
E1A98_RS19840	COG1011	Hydrolase
E1A98_RS19855	COG0456	acetyltransferase
E1A98_RS19860	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E1A98_RS19865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E1A98_RS19875	COG2864	formate dehydrogenase
E1A98_RS19880	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS19900	COG3711	transcriptional antiterminator
E1A98_RS19900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS19905	COG1363	Peptidase, m42
E1A98_RS19910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS19910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS19915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS19945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E1A98_RS19955	COG2258	MOSC domain
E1A98_RS19960	COG2205	protein histidine kinase activity
E1A98_RS19965	COG0745	RESPONSE REGULATOR receiver
E1A98_RS19970	COG3678	ATP-independent chaperone mediated protein folding
E1A98_RS19985	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
E1A98_RS20005	COG3152	Membrane
E1A98_RS20010	COG3691	Protein conserved in bacteria
E1A98_RS20015	COG0589	response to stress
E1A98_RS20020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E1A98_RS20025	COG1494	fructose-1,6-bisphosphatase
E1A98_RS20035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E1A98_RS20050	COG1575	Belongs to the MenA family. Type 1 subfamily
E1A98_RS20055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
E1A98_RS20065	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E1A98_RS20070	COG1609	Transcriptional regulator
E1A98_RS20075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E1A98_RS20085	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
E1A98_RS20095	COG0626	cystathionine gamma-synthase activity
E1A98_RS20100	COG0527	aspartate kinase activity
E1A98_RS20100	COG0460	homoserine dehydrogenase
E1A98_RS20105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E1A98_RS20115	COG0697	spore germination
E1A98_RS20120	COG3738	Protein conserved in bacteria
E1A98_RS20125	COG0371	Dehydrogenase
E1A98_RS20130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E1A98_RS20135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS20135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS20135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E1A98_RS20140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS20145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS20155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E1A98_RS20160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A98_RS20165	COG2207	Transcriptional regulator
E1A98_RS20170	COG2194	sulfuric ester hydrolase activity
E1A98_RS20195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E1A98_RS20205	COG0583	DNA-binding transcription factor activity
E1A98_RS20230	COG4206	TonB-dependent receptor
E1A98_RS20260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E1A98_RS20265	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
E1A98_RS20265	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
E1A98_RS20300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E1A98_RS20305	COG0250	Participates in transcription elongation, termination and antitermination
E1A98_RS20345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E1A98_RS20355	COG2104	thiamine diphosphate biosynthetic process
E1A98_RS20360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E1A98_RS20395	COG3068	Protein conserved in bacteria
E1A98_RS20400	COG0776	regulation of translation
E1A98_RS20410	COG3678	ATP-independent chaperone mediated protein folding
E1A98_RS20415	COG4191	Histidine kinase
E1A98_RS20420	COG2204	response regulator
E1A98_RS20425	COG0151	Belongs to the GarS family
E1A98_RS20460	COG0456	acetyltransferase
E1A98_RS20470	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E1A98_RS20475	COG2224	Isocitrate lyase
E1A98_RS20490	COG1414	Transcriptional regulator
E1A98_RS20495	COG1410	methionine synthase
E1A98_RS20495	COG0646	methionine synthase
E1A98_RS20500	COG1283	sodium-dependent phosphate transmembrane transporter activity
E1A98_RS20510	COG1187	pseudouridine synthase activity
E1A98_RS20520	COG0527	aspartate kinase activity
E1A98_RS20550	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E1A98_RS20565	COG0477	Major facilitator Superfamily
E1A98_RS20565	COG2814	Major facilitator Superfamily
E1A98_RS20570	COG3833	ABC-type maltose transport systems, permease component
E1A98_RS20575	COG1175	transmembrane transport
E1A98_RS20580	COG2182	Extracellular solute-binding protein
E1A98_RS20585	COG3842	ATPase activity
E1A98_RS20620	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E1A98_RS20630	COG0534	Mate efflux family protein
E1A98_RS20635	COG3237	CsbD-like
E1A98_RS20640	COG0735	belongs to the Fur family
E1A98_RS20655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E1A98_RS20665	COG0604	alcohol dehydrogenase
E1A98_RS20670	COG0305	Participates in initiation and elongation during chromosome replication
E1A98_RS20675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E1A98_RS20680	COG1448	Aminotransferase
E1A98_RS20690	COG3700	Belongs to the class B bacterial acid phosphatase family
E1A98_RS20695	COG0432	Pfam Uncharacterised protein family UPF0047
E1A98_RS20700	COG2315	Protein conserved in bacteria
E1A98_RS20705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E1A98_RS20710	COG0629	single-stranded DNA binding
E1A98_RS20720	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E1A98_RS20725	COG2207	Transcriptional regulator
E1A98_RS20730	COG0789	Transcriptional regulator
E1A98_RS20735	COG2252	PERMEase
E1A98_RS20740	COG0025	NhaP-type Na H and K H
E1A98_RS20745	COG1357	PFAM Pentapeptide repeats (8 copies)
E1A98_RS20755	COG3162	membrane
E1A98_RS20760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E1A98_RS20770	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E1A98_RS20775	COG0437	4 iron, 4 sulfur cluster binding
E1A98_RS20780	COG3301	Polysulphide reductase, NrfD
E1A98_RS20785	COG1138	Cytochrome C-type biogenesis protein
E1A98_RS20790	COG3088	subunit of a heme lyase
E1A98_RS20795	COG4235	cytochrome complex assembly
E1A98_RS20800	COG1301	dicarboxylic acid transport
E1A98_RS20805	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E1A98_RS20815	COG1538	Outer membrane efflux protein
E1A98_RS20820	COG1289	transmembrane transporter activity
E1A98_RS20825	COG1566	PFAM secretion protein HlyD family protein
E1A98_RS20835	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E1A98_RS20840	COG1940	carbohydrate kinase activity
E1A98_RS20845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E1A98_RS20850	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS20855	COG1129	ABC transporter
E1A98_RS20860	COG1879	ABC-type sugar transport system periplasmic component
E1A98_RS20865	COG1737	Transcriptional regulator
E1A98_RS20870	COG0698	ribose 5-phosphate isomerase
E1A98_RS20880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E1A98_RS20885	COG0456	acetyltransferase
E1A98_RS20890	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
E1A98_RS20895	COG3454	Phosphonate metabolism
E1A98_RS20900	COG4778	phosphonate C-P lyase system protein PhnL
E1A98_RS20905	COG4107	phosphonate C-P lyase system protein PhnK
E1A98_RS20910	COG3627	carbon phosphorus lyase activity
E1A98_RS20915	COG3626	phosphonate metabolism
E1A98_RS20920	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
E1A98_RS20925	COG3624	Phosphonate C-P lyase system protein PhnG
E1A98_RS20930	COG2188	Transcriptional regulator
E1A98_RS20940	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
E1A98_RS20945	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
E1A98_RS20950	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E1A98_RS20955	COG2824	Alkylphosphonate utilization operon protein PhnA
E1A98_RS20960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E1A98_RS20970	COG0477	Major facilitator Superfamily
E1A98_RS20980	COG0642	Histidine kinase
E1A98_RS20985	COG0745	RESPONSE REGULATOR receiver
E1A98_RS20990	COG2194	sulfuric ester hydrolase activity
E1A98_RS20995	COG0531	amino acid
E1A98_RS21000	COG2207	Transcriptional regulator
E1A98_RS21005	COG1982	Orn Lys Arg decarboxylase major
E1A98_RS21010	COG2169	Transcriptional regulator
E1A98_RS21015	COG1486	melibiose metabolic process
E1A98_RS21020	COG2211	Major facilitator Superfamily
E1A98_RS21025	COG3647	Membrane
E1A98_RS21030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E1A98_RS21030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E1A98_RS21035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E1A98_RS21040	COG4565	transcriptional regulatory protein
E1A98_RS21045	COG3290	protein histidine kinase activity
E1A98_RS21050	COG3592	Divergent 4Fe-4S mono-cluster
E1A98_RS21055	COG2388	GCN5-related N-acetyl-transferase
E1A98_RS21070	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E1A98_RS21075	COG3104	oligopeptide transport
E1A98_RS21080	COG1982	Orn Lys Arg decarboxylase major
E1A98_RS21085	COG0531	amino acid
E1A98_RS21090	COG3710	Transcriptional regulator
E1A98_RS21100	COG1309	transcriptional regulator
E1A98_RS21105	COG4232	protein-disulfide reductase activity
E1A98_RS21115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E1A98_RS21120	COG1027	Aspartate ammonia-lyase
E1A98_RS21125	COG3030	protein affecting phage T7 exclusion by the F plasmid
E1A98_RS21130	COG0531	amino acid
E1A98_RS21155	COG1509	lysine 2,3-aminomutase activity
E1A98_RS21165	COG5510	response to toxic substance
E1A98_RS21170	COG5510	response to toxic substance
E1A98_RS21175	COG2076	Multidrug Resistance protein
E1A98_RS21180	COG3040	lipid binding
E1A98_RS21185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E1A98_RS21200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E1A98_RS21205	COG1053	succinate dehydrogenase
E1A98_RS21215	COG0531	amino acid
E1A98_RS21230	COG1511	domain protein
E1A98_RS21230	COG3264	Mechanosensitive ion channel
E1A98_RS21270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E1A98_RS21275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E1A98_RS21275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E1A98_RS21280	COG0802	atpase or kinase
E1A98_RS21285	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A98_RS21305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E1A98_RS21310	COG0330	HflC and HflK could
E1A98_RS21315	COG0330	HflC and HflK could
E1A98_RS21320	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E1A98_RS21335	COG0557	exoribonuclease II activity
E1A98_RS21340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E1A98_RS21345	COG3789	protein conserved in bacteria
E1A98_RS21350	COG1842	Phage shock protein A
E1A98_RS21360	COG3766	membrane
E1A98_RS21365	COG5463	Belongs to the UPF0441 family
E1A98_RS21370	COG0754	glutathionylspermidine amidase activity
E1A98_RS21375	COG1960	acyl-CoA dehydrogenase activity
E1A98_RS21385	COG3650	response to hydrogen peroxide
E1A98_RS21390	COG1073	alpha beta
E1A98_RS21405	COG3037	sugar-specific permease SgaT UlaA
E1A98_RS21410	COG3414	Phosphotransferase system galactitol-specific IIB component
E1A98_RS21415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS21470	COG3061	Opacity-associated protein A
E1A98_RS21475	COG0545	Peptidyl-prolyl cis-trans isomerase
E1A98_RS21480	COG1113	amino acid transport
E1A98_RS21490	COG0697	spore germination
E1A98_RS21495	COG0702	epimerase
E1A98_RS21500	COG1733	regulation of RNA biosynthetic process
E1A98_RS21505	COG0737	Belongs to the 5'-nucleotidase family
E1A98_RS21510	COG1218	3'(2'),5'-bisphosphate nucleotidase
E1A98_RS21520	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E1A98_RS21530	COG1253	flavin adenine dinucleotide binding
E1A98_RS21540	COG0729	surface antigen
E1A98_RS21545	COG2911	Protein conserved in bacteria
E1A98_RS21550	COG2105	PFAM AIG2 family protein
E1A98_RS21555	COG2336	PFAM SpoVT AbrB
E1A98_RS21560	COG2337	Toxic component of a toxin-antitoxin (TA) module
E1A98_RS21565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E1A98_RS21570	COG1879	ABC-type sugar transport system periplasmic component
E1A98_RS21575	COG1129	ABC transporter
E1A98_RS21580	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS21585	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A98_RS21595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E1A98_RS21605	COG0312	modulator of DNA gyrase
E1A98_RS21610	COG3783	Cytochrome b(562)
E1A98_RS21615	COG0602	queuosine metabolic process
E1A98_RS21620	COG1328	CTP reductase activity
E1A98_RS21625	COG0366	Alpha amylase catalytic
E1A98_RS21630	COG1263	PTS System
E1A98_RS21630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A98_RS21635	COG1609	Transcriptional regulator
E1A98_RS21645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E1A98_RS21650	COG0251	oxidation-reduction process
E1A98_RS21670	COG0251	oxidation-reduction process
E1A98_RS21675	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS21680	COG1309	transcriptional regulator
E1A98_RS21685	COG2731	YhcH YjgK YiaL family protein
E1A98_RS21695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E1A98_RS21700	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
E1A98_RS21705	COG0456	acetyltransferase
E1A98_RS21710	COG4269	membrane
E1A98_RS21715	COG0525	valine-tRNA ligase activity
E1A98_RS21720	COG2927	DNA polymerase III (CHI subunit)
E1A98_RS21730	COG0795	lipopolysaccharide-transporting ATPase activity
E1A98_RS21735	COG0795	lipopolysaccharide-transporting ATPase activity
E1A98_RS21740	COG0433	COG0433 Predicted ATPase
E1A98_RS21745	COG1609	Transcriptional regulator
E1A98_RS21750	COG2610	gluconate transmembrane transporter activity
E1A98_RS21755	COG1028	Short-chain dehydrogenase reductase Sdr
E1A98_RS21760	COG1063	alcohol dehydrogenase
E1A98_RS21765	COG3265	gluconokinase activity
E1A98_RS21770	COG1064	alcohol dehydrogenase
E1A98_RS21805	COG3385	transposase activity
E1A98_RS21810	COG2814	Major facilitator Superfamily
E1A98_RS21815	COG0673	inositol 2-dehydrogenase activity
E1A98_RS21840	COG2826	transposase and inactivated derivatives, IS30 family
E1A98_RS21855	COG2085	NADP oxidoreductase coenzyme F420-dependent
E1A98_RS21860	COG1120	ATPase activity
E1A98_RS21865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A98_RS21870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A98_RS21875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E1A98_RS21880	COG4772	TonB-dependent receptor
E1A98_RS21885	COG3712	iron ion homeostasis
E1A98_RS21890	COG1595	DNA-templated transcription, initiation
E1A98_RS21900	COG2390	Transcriptional regulator
E1A98_RS21905	COG2610	gluconate transmembrane transporter activity
E1A98_RS21910	COG0129	dihydroxy-acid dehydratase activity
E1A98_RS21915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E1A98_RS21920	COG1414	Transcriptional regulator
E1A98_RS21925	COG1349	DNA-binding transcription factor activity
E1A98_RS21930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E1A98_RS21935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A98_RS21940	COG0434	BtpA family
E1A98_RS21945	COG3775	system Galactitol-specific IIC component
E1A98_RS21950	COG3414	Phosphotransferase system galactitol-specific IIB component
E1A98_RS21955	COG1363	Peptidase, m42
E1A98_RS21965	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E1A98_RS21970	COG3153	acetyltransferase
E1A98_RS21985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A98_RS21985	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E1A98_RS21995	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
E1A98_RS22000	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E1A98_RS22005	COG0582	viral genome integration into host DNA
E1A98_RS22010	COG4974	Belongs to the 'phage' integrase family
E1A98_RS22015	COG2610	gluconate transmembrane transporter activity
E1A98_RS22025	COG0246	Mannitol dehydrogenase
E1A98_RS22030	COG2186	Transcriptional regulator
E1A98_RS22050	COG0583	DNA-binding transcription factor activity
E1A98_RS22055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E1A98_RS22060	COG0700	Nucleoside recognition
E1A98_RS22065	COG3366	ferrous iron transmembrane transporter activity
E1A98_RS22075	COG0477	Major facilitator Superfamily
E1A98_RS22080	COG3204	pilus organization
E1A98_RS22090	COG1924	4 iron, 4 sulfur cluster binding
E1A98_RS22095	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
E1A98_RS22100	COG2733	membrane
E1A98_RS22105	COG2814	Major facilitator Superfamily
E1A98_RS22115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A98_RS22120	COG5457	Domain of unknown function (DUF1127)
E1A98_RS22125	COG1196	nuclear chromosome segregation
E1A98_RS22135	COG4268	DNA restriction-modification system
E1A98_RS22140	COG1401	restriction endodeoxyribonuclease activity
E1A98_RS22150	COG0732	type I restriction modification DNA specificity domain
E1A98_RS22155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E1A98_RS22165	COG1715	Restriction endonuclease
E1A98_RS22170	COG0523	cobalamin synthesis protein
E1A98_RS22175	COG2879	small protein
E1A98_RS22180	COG1966	Carbon starvation protein
E1A98_RS22185	COG0840	transmembrane signaling receptor activity
E1A98_RS22190	COG2271	Major facilitator Superfamily
E1A98_RS22195	COG1802	Transcriptional regulator
E1A98_RS22200	COG1063	alcohol dehydrogenase
E1A98_RS22215	COG1484	DNA-dependent DNA replication
E1A98_RS22235	COG2197	response regulator
E1A98_RS22240	COG2197	response regulator
E1A98_RS22245	COG4114	ferric iron reductase
E1A98_RS22275	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E1A98_RS22280	COG0456	acetyltransferase
E1A98_RS22285	COG1011	Hydrolase
E1A98_RS22295	COG2823	Periplasmic or secreted lipoprotein
E1A98_RS22305	COG4667	esterase of the alpha-beta hydrolase superfamily
E1A98_RS22310	COG0084	hydrolase, TatD family'
E1A98_RS22315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E1A98_RS22320	COG1328	CTP reductase activity
E1A98_RS22345	COG3550	peptidyl-serine autophosphorylation
E1A98_RS22360	COG0560	Phosphoserine phosphatase
E1A98_RS22365	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E1A98_RS22370	COG3172	ATPase kinase involved in NAD metabolism
E1A98_RS22370	COG1056	cytidyltransferase-related domain
E1A98_RS22375	COG0488	(ABC) transporter
E1A98_RS22380	COG0741	lytic transglycosylase activity
E1A98_RS22400	COG3708	Transcriptional regulator
E1A98_RS22400	COG2207	Transcriptional regulator
E1A98_RS22405	COG3045	CreA protein
E1A98_RS22410	COG0745	RESPONSE REGULATOR receiver
E1A98_RS22415	COG2205	protein histidine kinase activity
E1A98_RS22420	COG4452	Inner membrane protein CreD
E1A98_RS22425	COG0745	RESPONSE REGULATOR receiver
E1A98_RS22435	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA