locus-tag	class	description
BCV59_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
BCV59_RS00210	COG0284	orotidine-5'-phosphate decarboxylase activity
BCV59_RS00385	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS00400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV59_RS00480	COG1554	hydrolase, family 65, central catalytic
BCV59_RS00485	COG1554	hydrolase, family 65, central catalytic
BCV59_RS00690	COG0135	phosphoribosylanthranilate isomerase activity
BCV59_RS00690	COG0134	indole-3-glycerol-phosphate synthase activity
BCV59_RS00695	COG0512	Glutamine amidotransferase of anthranilate synthase
BCV59_RS00695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV59_RS00715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV59_RS00800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCV59_RS00885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV59_RS00950	COG0583	DNA-binding transcription factor activity
BCV59_RS00970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCV59_RS01000	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCV59_RS01020	COG5001	Diguanylate cyclase
BCV59_RS01090	COG4168	peptide transport system, permease
BCV59_RS01145	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS01165	COG3685	Protein conserved in bacteria
BCV59_RS01170	COG3685	Protein conserved in bacteria
BCV59_RS01175	COG3729	General stress protein
BCV59_RS01190	COG0134	indole-3-glycerol-phosphate synthase activity
BCV59_RS01190	COG0135	phosphoribosylanthranilate isomerase activity
BCV59_RS01195	COG0512	Glutamine amidotransferase of anthranilate synthase
BCV59_RS01195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV59_RS01200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV59_RS01205	COG0613	PHP domain protein
BCV59_RS01210	COG0009	L-threonylcarbamoyladenylate synthase
BCV59_RS01215	COG1187	pseudouridine synthase activity
BCV59_RS01220	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BCV59_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS01235	COG0616	signal peptide processing
BCV59_RS01250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV59_RS01255	COG0583	DNA-binding transcription factor activity
BCV59_RS01275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCV59_RS01285	COG0671	phosphoesterase, PA-phosphatase related
BCV59_RS01290	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BCV59_RS01295	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCV59_RS01305	COG0023	Translation Initiation Factor
BCV59_RS01315	COG1349	DNA-binding transcription factor activity
BCV59_RS01325	COG5001	Diguanylate cyclase
BCV59_RS01335	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV59_RS01335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV59_RS01340	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCV59_RS01345	COG2852	Protein conserved in bacteria
BCV59_RS01350	COG4172	Belongs to the ABC transporter superfamily
BCV59_RS01355	COG4172	Belongs to the ABC transporter superfamily
BCV59_RS01360	COG4171	peptide transport system, permease
BCV59_RS01365	COG4168	peptide transport system, permease
BCV59_RS01370	COG4166	transmembrane transport
BCV59_RS01385	COG0531	amino acid
BCV59_RS01390	COG0174	glutamine synthetase
BCV59_RS01395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BCV59_RS01400	COG1917	Cupin 2, conserved barrel domain protein
BCV59_RS01400	COG1396	sequence-specific DNA binding
BCV59_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS01410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV59_RS01415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCV59_RS01420	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCV59_RS01425	COG1842	Phage shock protein A
BCV59_RS01435	COG1983	PspC domain protein
BCV59_RS01445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV59_RS01450	COG0366	Alpha amylase catalytic
BCV59_RS01455	COG1653	transport
BCV59_RS01460	COG1063	alcohol dehydrogenase
BCV59_RS01465	COG1082	Xylose isomerase domain protein TIM barrel
BCV59_RS01470	COG0673	inositol 2-dehydrogenase activity
BCV59_RS01480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV59_RS01485	COG3842	ATPase activity
BCV59_RS01495	COG1609	Transcriptional regulator
BCV59_RS01500	COG3106	COG3106 Predicted ATPase
BCV59_RS01510	COG3283	Transcriptional regulator of aromatic amino acids metabolism
BCV59_RS01520	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCV59_RS01525	COG4948	Mandelate Racemase Muconate Lactonizing
BCV59_RS01530	COG2866	Carboxypeptidase
BCV59_RS01535	COG0702	epimerase
BCV59_RS01540	COG1073	alpha beta
BCV59_RS01545	COG1073	alpha beta
BCV59_RS01555	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCV59_RS01560	COG4166	transmembrane transport
BCV59_RS01565	COG0668	transmembrane transport
BCV59_RS01570	COG3182	Iron-regulated membrane protein
BCV59_RS01575	COG0589	response to stress
BCV59_RS01580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV59_RS01585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV59_RS01590	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BCV59_RS01600	COG2207	Transcriptional regulator
BCV59_RS01615	COG2840	Smr protein MutS2
BCV59_RS01620	COG3706	GGDEF domain
BCV59_RS01635	COG0513	Belongs to the DEAD box helicase family
BCV59_RS01645	COG0589	response to stress
BCV59_RS01650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV59_RS01655	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCV59_RS01655	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCV59_RS01655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCV59_RS01655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV59_RS01660	COG3042	response to heat
BCV59_RS01665	COG3187	Heat shock protein
BCV59_RS01670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCV59_RS01675	COG2911	Protein conserved in bacteria
BCV59_RS01685	COG3784	Protein of unknown function (DUF1318)
BCV59_RS01690	COG2207	Transcriptional regulator
BCV59_RS01695	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS01700	COG3733	amine oxidase
BCV59_RS01705	COG2030	dehydratase
BCV59_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS01710	COG3396	Phenylacetate-CoA oxygenase
BCV59_RS01715	COG3460	Phenylacetate-CoA oxygenase
BCV59_RS01720	COG3396	Phenylacetate-CoA oxygenase
BCV59_RS01725	COG2151	metal-sulfur cluster biosynthetic enzyme
BCV59_RS01730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV59_RS01735	COG1024	Enoyl-CoA hydratase
BCV59_RS01740	COG1024	Enoyl-CoA hydratase
BCV59_RS01745	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCV59_RS01750	COG2050	protein possibly involved in aromatic compounds catabolism
BCV59_RS01755	COG0183	Belongs to the thiolase family
BCV59_RS01760	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BCV59_RS01765	COG3327	negative regulation of DNA-templated transcription, initiation
BCV59_RS01770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV59_RS01775	COG0667	Aldo Keto reductase
BCV59_RS01785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCV59_RS01795	COG2267	carboxylic ester hydrolase activity
BCV59_RS01800	COG0671	phosphoesterase, PA-phosphatase related
BCV59_RS01800	COG2453	phosphatase
BCV59_RS01810	COG1643	Atp-dependent helicase
BCV59_RS01815	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCV59_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS01825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV59_RS01830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV59_RS01835	COG3038	cytochrome b561
BCV59_RS01850	COG0840	transmembrane signaling receptor activity
BCV59_RS01855	COG0583	DNA-binding transcription factor activity
BCV59_RS01860	COG5383	Protein conserved in bacteria
BCV59_RS01875	COG2841	Protein conserved in bacteria
BCV59_RS01880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV59_RS01885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV59_RS01890	COG1275	C4-dicarboxylate transporter malic acid transport protein
BCV59_RS01895	COG0500	methyltransferase
BCV59_RS01915	COG0675	Transposase, IS605 OrfB family
BCV59_RS01920	COG3135	benzoate transporter
BCV59_RS01925	COG1396	sequence-specific DNA binding
BCV59_RS01930	COG0826	peptidase U32
BCV59_RS01940	COG1724	mRNA binding
BCV59_RS01945	COG1598	PFAM Uncharacterised protein family UPF0150
BCV59_RS01950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV59_RS01955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCV59_RS01960	COG3842	ATPase activity
BCV59_RS01965	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCV59_RS01970	COG1177	transmembrane transport
BCV59_RS02000	COG3238	Protein conserved in bacteria
BCV59_RS02005	COG1247	-acetyltransferase
BCV59_RS02010	COG2130	NADP-dependent
BCV59_RS02015	COG1802	Transcriptional regulator
BCV59_RS02020	COG4772	TonB-dependent receptor
BCV59_RS02025	COG3391	amine dehydrogenase activity
BCV59_RS02030	COG1113	amino acid transport
BCV59_RS02035	COG0625	glutathione transferase activity
BCV59_RS02055	COG5433	transposase activity
BCV59_RS02065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCV59_RS02070	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BCV59_RS02075	COG0384	phenazine biosynthesis protein PhzF
BCV59_RS02080	COG2181	nitrate reductase activity
BCV59_RS02085	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCV59_RS02090	COG1140	nitrate reductase beta subunit
BCV59_RS02095	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCV59_RS02100	COG2223	nitrite transmembrane transporter activity
BCV59_RS02110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV59_RS02115	COG0697	spore germination
BCV59_RS02120	COG3383	formate dehydrogenase (NAD+) activity
BCV59_RS02120	COG0243	molybdopterin cofactor binding
BCV59_RS02125	COG3383	formate dehydrogenase (NAD+) activity
BCV59_RS02125	COG0243	molybdopterin cofactor binding
BCV59_RS02130	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS02135	COG2864	formate dehydrogenase
BCV59_RS02140	COG3093	addiction module antidote protein HigA
BCV59_RS02145	COG1064	alcohol dehydrogenase
BCV59_RS02165	COG1764	response to oxidative stress
BCV59_RS02170	COG4608	Belongs to the ABC transporter superfamily
BCV59_RS02175	COG0444	Belongs to the ABC transporter superfamily
BCV59_RS02180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV59_RS02185	COG0601	transmembrane transport
BCV59_RS02190	COG0747	negative chemotaxis
BCV59_RS02195	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BCV59_RS02200	COG2199	diguanylate cyclase activity
BCV59_RS02200	COG2200	EAL domain
BCV59_RS02200	COG2202	Pas domain
BCV59_RS02210	COG1649	PFAM Uncharacterised BCR, COG1649
BCV59_RS02215	COG0531	amino acid
BCV59_RS02220	COG0076	glutamate decarboxylase activity
BCV59_RS02230	COG0612	Peptidase, M16
BCV59_RS02235	COG4771	TonB-dependent receptor
BCV59_RS02240	COG4178	(ABC) transporter
BCV59_RS02245	COG0641	radical SAM
BCV59_RS02250	COG3119	arylsulfatase activity
BCV59_RS02265	COG0243	molybdopterin cofactor binding
BCV59_RS02270	COG3539	Fimbrial protein
BCV59_RS02275	COG3539	Fimbrial protein
BCV59_RS02280	COG3188	usher protein
BCV59_RS02290	COG3539	Fimbrial protein
BCV59_RS02295	COG4977	sequence-specific DNA binding
BCV59_RS02300	COG3550	peptidyl-serine autophosphorylation
BCV59_RS02305	COG1396	sequence-specific DNA binding
BCV59_RS02365	COG3781	membrane
BCV59_RS02375	COG2199	diguanylate cyclase activity
BCV59_RS02385	COG0697	spore germination
BCV59_RS02390	COG2814	Major facilitator Superfamily
BCV59_RS02400	COG3706	GGDEF domain
BCV59_RS02405	COG3111	PFAM Bacterial OB fold (BOF) protein
BCV59_RS02410	COG1546	Belongs to the CinA family
BCV59_RS02415	COG0339	signal peptide processing
BCV59_RS02420	COG4221	oxidoreductase activity
BCV59_RS02425	COG1802	Transcriptional regulator
BCV59_RS02435	COG0246	Mannitol dehydrogenase
BCV59_RS02440	COG0477	Major facilitator Superfamily
BCV59_RS02470	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS02570	COG3772	lysozyme
BCV59_RS02585	COG3772	lysozyme
BCV59_RS02635	COG0484	heat shock protein binding
BCV59_RS02640	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BCV59_RS02645	COG1403	HNH endonuclease
BCV59_RS02655	COG3111	PFAM Bacterial OB fold (BOF) protein
BCV59_RS02685	COG1846	Transcriptional regulator
BCV59_RS02690	COG1484	DNA-dependent DNA replication
BCV59_RS02695	COG1846	Transcriptional regulator
BCV59_RS02750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS02760	COG0582	viral genome integration into host DNA
BCV59_RS02770	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS02775	COG4372	Transposase
BCV59_RS02795	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS02800	COG4372	Transposase
BCV59_RS02845	COG2207	Transcriptional regulator
BCV59_RS02865	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BCV59_RS02870	COG1403	HNH endonuclease
BCV59_RS02910	COG1846	Transcriptional regulator
BCV59_RS02915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS02930	COG0582	viral genome integration into host DNA
BCV59_RS02940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS02955	COG0243	molybdopterin cofactor binding
BCV59_RS02960	COG0243	molybdopterin cofactor binding
BCV59_RS02965	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS02970	COG3302	dmso reductase anchor subunit
BCV59_RS02975	COG3381	protein complex oligomerization
BCV59_RS02985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCV59_RS02990	COG1940	carbohydrate kinase activity
BCV59_RS02995	COG0583	DNA-binding transcription factor activity
BCV59_RS03000	COG2814	Major facilitator Superfamily
BCV59_RS03015	COG3591	Belongs to the peptidase S1B family
BCV59_RS03030	COG0628	permease
BCV59_RS03035	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BCV59_RS03040	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BCV59_RS03050	COG0531	amino acid
BCV59_RS03060	COG3136	membrane protein required for alginate biosynthesis
BCV59_RS03065	COG0745	RESPONSE REGULATOR receiver
BCV59_RS03070	COG2205	protein histidine kinase activity
BCV59_RS03080	COG0114	fumarate hydratase activity
BCV59_RS03085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV59_RS03085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV59_RS03090	COG1482	cell wall glycoprotein biosynthetic process
BCV59_RS03095	COG5339	Protein conserved in bacteria
BCV59_RS03110	COG3250	beta-galactosidase activity
BCV59_RS03115	COG1309	transcriptional regulator
BCV59_RS03120	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS03125	COG1609	Transcriptional regulator
BCV59_RS03130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS03130	COG1263	PTS System
BCV59_RS03135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCV59_RS03145	COG0673	inositol 2-dehydrogenase activity
BCV59_RS03185	COG4659	FMN binding
BCV59_RS03195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCV59_RS03205	COG3104	oligopeptide transport
BCV59_RS03210	COG0625	glutathione transferase activity
BCV59_RS03215	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BCV59_RS03230	COG3895	Periplasmic Protein
BCV59_RS03240	COG3133	Outer membrane lipoprotein
BCV59_RS03255	COG1566	PFAM secretion protein HlyD family protein
BCV59_RS03260	COG1289	transmembrane transporter activity
BCV59_RS03265	COG2032	superoxide dismutase activity
BCV59_RS03270	COG4989	oxidoreductase activity
BCV59_RS03275	COG3313	Fe-S protein
BCV59_RS03280	COG1309	transcriptional regulator
BCV59_RS03285	COG1902	pentaerythritol trinitrate reductase activity
BCV59_RS03290	COG0346	lactoylglutathione lyase activity
BCV59_RS03305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV59_RS03310	COG0791	NLP P60 protein
BCV59_RS03315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV59_RS03320	COG2814	Major facilitator Superfamily
BCV59_RS03335	COG0583	DNA-binding transcription factor activity
BCV59_RS03340	COG2814	Major facilitator Superfamily
BCV59_RS03345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCV59_RS03350	COG0307	riboflavin synthase, alpha
BCV59_RS03360	COG3468	outer membrane autotransporter barrel domain protein
BCV59_RS03380	COG4529	Protein conserved in bacteria
BCV59_RS03390	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
BCV59_RS03395	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS03410	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS03420	COG0469	pyruvate kinase activity
BCV59_RS03425	COG4238	major outer membrane lipoprotein
BCV59_RS03430	COG1376	ErfK ybiS ycfS ynhG family protein
BCV59_RS03445	COG0719	Fe-S assembly protein
BCV59_RS03450	COG0396	ATPase activity
BCV59_RS03455	COG0719	Fe-S assembly protein
BCV59_RS03460	COG0316	Belongs to the HesB IscA family
BCV59_RS03470	COG2050	protein possibly involved in aromatic compounds catabolism
BCV59_RS03475	COG0247	lactate metabolic process
BCV59_RS03475	COG0277	FAD linked oxidase domain protein
BCV59_RS03480	COG0628	permease
BCV59_RS03495	COG0738	Major facilitator superfamily
BCV59_RS03500	COG2271	Major facilitator Superfamily
BCV59_RS03515	COG4670	ketone body catabolic process
BCV59_RS03520	COG1960	acyl-CoA dehydrogenase activity
BCV59_RS03525	COG1917	Cupin 2, conserved barrel domain protein
BCV59_RS03525	COG2207	Transcriptional regulator
BCV59_RS03535	COG2086	electron transfer activity
BCV59_RS03540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCV59_RS03545	COG0644	oxidoreductase
BCV59_RS03550	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BCV59_RS03555	COG0318	PFAM AMP-dependent synthetase and ligase
BCV59_RS03560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV59_RS03560	COG0574	Belongs to the PEP-utilizing enzyme family
BCV59_RS03575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV59_RS03580	COG4256	Hemin uptake protein
BCV59_RS03590	COG2200	EAL domain
BCV59_RS03595	COG0791	NLP P60 protein
BCV59_RS03605	COG0386	Belongs to the glutathione peroxidase family
BCV59_RS03670	COG3137	Salt-induced outer membrane protein
BCV59_RS03675	COG1105	Belongs to the carbohydrate kinase PfkB family
BCV59_RS03685	COG3001	Fructosamine kinase
BCV59_RS03695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV59_RS03700	COG1988	membrane-bound metal-dependent
BCV59_RS03705	COG1823	symporter activity
BCV59_RS03720	COG0753	catalase activity
BCV59_RS03730	COG1486	melibiose metabolic process
BCV59_RS03735	COG1917	Cupin 2, conserved barrel domain protein
BCV59_RS03735	COG2169	Transcriptional regulator
BCV59_RS03740	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV59_RS03745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV59_RS03750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV59_RS03755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV59_RS03770	COG0322	excinuclease ABC activity
BCV59_RS03780	COG3678	ATP-independent chaperone mediated protein folding
BCV59_RS03810	COG0708	Exodeoxyribonuclease III
BCV59_RS03815	COG0398	Pfam SNARE associated Golgi protein
BCV59_RS03825	COG0398	Pfam SNARE associated Golgi protein
BCV59_RS03830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV59_RS03835	COG4134	Bacterial extracellular solute-binding protein
BCV59_RS03840	COG4135	transport system, permease component
BCV59_RS03845	COG4136	ATPase activity
BCV59_RS03850	COG2897	thiosulfate sulfurtransferase activity
BCV59_RS03855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCV59_RS03860	COG0494	nUDIX hydrolase
BCV59_RS03870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCV59_RS03880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV59_RS03895	COG0778	Nitroreductase
BCV59_RS03905	COG0616	signal peptide processing
BCV59_RS03910	COG0252	asparaginase activity
BCV59_RS03915	COG1335	isochorismatase
BCV59_RS03920	COG2814	Major facilitator Superfamily
BCV59_RS03925	COG1349	DNA-binding transcription factor activity
BCV59_RS03930	COG0667	Aldo Keto reductase
BCV59_RS03935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS03945	COG1063	alcohol dehydrogenase
BCV59_RS03950	COG2271	Major facilitator Superfamily
BCV59_RS03955	COG1063	alcohol dehydrogenase
BCV59_RS03960	COG3139	Protein of unknown function (DUF1315)
BCV59_RS03970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV59_RS03975	COG0676	glucose-6-phosphate 1-epimerase activity
BCV59_RS03980	COG0656	L-ascorbic acid biosynthetic process
BCV59_RS03985	COG3713	MltA-interacting MipA family protein
BCV59_RS03990	COG2766	serine protein kinase
BCV59_RS04000	COG2199	diguanylate cyclase activity
BCV59_RS04005	COG2199	diguanylate cyclase activity
BCV59_RS04010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCV59_RS04025	COG2207	Transcriptional regulator
BCV59_RS04035	COG3189	MarR family transcriptional regulator
BCV59_RS04040	COG3042	response to heat
BCV59_RS04045	COG2203	Gaf domain
BCV59_RS04045	COG2199	diguanylate cyclase activity
BCV59_RS04055	COG2261	transglycosylase associated protein
BCV59_RS04065	COG3615	Tellurite resistance protein tehB
BCV59_RS04075	COG0583	DNA-binding transcription factor activity
BCV59_RS04090	COG0583	DNA-binding transcription factor activity
BCV59_RS04095	COG0473	3-isopropylmalate dehydrogenase activity
BCV59_RS04100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCV59_RS04105	COG4638	Rieske (2fe-2S)
BCV59_RS04110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV59_RS04115	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BCV59_RS04120	COG0318	PFAM AMP-dependent synthetase and ligase
BCV59_RS04125	COG3065	identical protein binding
BCV59_RS04130	COG1214	PFAM Peptidase M22, glycoprotease
BCV59_RS04135	COG1199	ATP-dependent helicase activity
BCV59_RS04140	COG0251	oxidation-reduction process
BCV59_RS04155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV59_RS04165	COG1760	l-serine dehydratase
BCV59_RS04170	COG2200	EAL domain
BCV59_RS04185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS04185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS04190	COG3715	PTS system
BCV59_RS04195	COG3716	PTS system mannose fructose sorbose family IID component
BCV59_RS04215	COG2226	methyltransferase
BCV59_RS04250	COG1414	Transcriptional regulator
BCV59_RS04255	COG2814	Major facilitator Superfamily
BCV59_RS04265	COG0793	Belongs to the peptidase S41A family
BCV59_RS04275	COG1956	GAF domain-containing protein
BCV59_RS04280	COG2995	paraquat-inducible protein a
BCV59_RS04285	COG3008	intermembrane lipid transfer
BCV59_RS04305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV59_RS04320	COG1276	copper resistance
BCV59_RS04325	COG2372	response to copper ion
BCV59_RS04335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV59_RS04340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS04345	COG1770	oligopeptidase
BCV59_RS04350	COG2979	Protein of unknown function (DUF533)
BCV59_RS04365	COG3141	response to X-ray
BCV59_RS04375	COG0800	Aldolase
BCV59_RS04380	COG0129	dihydroxy-acid dehydratase activity
BCV59_RS04385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCV59_RS04395	COG1737	Transcriptional regulator
BCV59_RS04400	COG0469	pyruvate kinase activity
BCV59_RS04405	COG1560	Kdo2-lipid A biosynthetic process
BCV59_RS04415	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BCV59_RS04425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV59_RS04450	COG0217	transcriptional regulatory protein
BCV59_RS04455	COG0494	nUDIX hydrolase
BCV59_RS04465	COG1335	isochorismatase
BCV59_RS04485	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS04560	COG0740	serine-type endopeptidase activity
BCV59_RS04600	COG3772	lysozyme
BCV59_RS04670	COG1403	HNH endonuclease
BCV59_RS04680	COG0305	Participates in initiation and elongation during chromosome replication
BCV59_RS04685	COG1484	DNA-dependent DNA replication
BCV59_RS04710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV59_RS04755	COG0582	viral genome integration into host DNA
BCV59_RS04760	COG1801	Protein of unknown function DUF72
BCV59_RS04765	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BCV59_RS04780	COG0243	molybdopterin cofactor binding
BCV59_RS04785	COG3005	denitrification pathway
BCV59_RS04795	COG3102	Protein conserved in bacteria
BCV59_RS04805	COG3755	Protein conserved in bacteria
BCV59_RS04815	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCV59_RS04820	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCV59_RS04830	COG0745	RESPONSE REGULATOR receiver
BCV59_RS04840	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCV59_RS04845	COG0840	transmembrane signaling receptor activity
BCV59_RS04850	COG0840	transmembrane signaling receptor activity
BCV59_RS04855	COG0835	chemotaxis
BCV59_RS04860	COG2198	Histidine kinase
BCV59_RS04860	COG0643	Histidine kinase
BCV59_RS04865	COG1360	Flagellar Motor Protein
BCV59_RS04870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCV59_RS04885	COG0589	response to stress
BCV59_RS04895	COG1877	trehalose-phosphatase activity
BCV59_RS04900	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV59_RS04905	COG1129	ABC transporter
BCV59_RS04910	COG1879	ABC-type sugar transport system periplasmic component
BCV59_RS04915	COG1528	Iron-storage protein
BCV59_RS04935	COG1528	Iron-storage protein
BCV59_RS04945	COG0814	amino acid
BCV59_RS04950	COG3318	Belongs to the UPF0149 family
BCV59_RS04950	COG3012	SEC-C Motif Domain Protein
BCV59_RS04980	COG2197	response regulator
BCV59_RS04995	COG2197	response regulator
BCV59_RS05000	COG1126	abc transporter atp-binding protein
BCV59_RS05005	COG0765	amino acid transport
BCV59_RS05015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS05025	COG1191	sigma factor activity
BCV59_RS05030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCV59_RS05035	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BCV59_RS05040	COG1516	flagellar protein fliS
BCV59_RS05050	COG0366	Alpha amylase catalytic
BCV59_RS05060	COG2391	methyltransferase activity
BCV59_RS05065	COG0425	Belongs to the sulfur carrier protein TusA family
BCV59_RS05070	COG2135	peptidase activity
BCV59_RS05085	COG1766	The M ring may be actively involved in energy transduction
BCV59_RS05090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCV59_RS05095	COG1317	bacterial-type flagellum organization
BCV59_RS05100	COG1157	protein secretion by the type III secretion system
BCV59_RS05105	COG2882	bacterial-type flagellum organization
BCV59_RS05110	COG3144	bacterial-type flagellum assembly
BCV59_RS05115	COG1580	Controls the rotational direction of flagella during chemotaxis
BCV59_RS05120	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCV59_RS05125	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCV59_RS05130	COG3190	flagellar
BCV59_RS05135	COG1338	Plays a role in the flagellum-specific transport system
BCV59_RS05140	COG1987	bacterial-type flagellum assembly
BCV59_RS05145	COG1684	flagellar biosynthetic protein fliR
BCV59_RS05150	COG2197	response regulator
BCV59_RS05175	COG5475	Uncharacterized small protein (DUF2158)
BCV59_RS05180	COG2354	Protein conserved in bacteria
BCV59_RS05185	COG0697	spore germination
BCV59_RS05190	COG3727	T/G mismatch-specific endonuclease activity
BCV59_RS05195	COG0270	DNA (cytosine-5-)-methyltransferase activity
BCV59_RS05200	COG1418	mRNA catabolic process
BCV59_RS05215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV59_RS05230	COG2205	protein histidine kinase activity
BCV59_RS05235	COG0745	RESPONSE REGULATOR receiver
BCV59_RS05240	COG2351	hydroxyisourate hydrolase activity
BCV59_RS05255	COG3443	Belongs to the bacterial solute-binding protein 9 family
BCV59_RS05260	COG3038	cytochrome b561
BCV59_RS05285	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS05290	COG1403	HNH endonuclease
BCV59_RS05305	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS05310	COG4372	Transposase
BCV59_RS05355	COG3772	lysozyme
BCV59_RS05370	COG3772	lysozyme
BCV59_RS05405	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BCV59_RS05410	COG1403	HNH endonuclease
BCV59_RS05455	COG1846	Transcriptional regulator
BCV59_RS05480	COG1396	sequence-specific DNA binding
BCV59_RS05520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS05540	COG0582	viral genome integration into host DNA
BCV59_RS05545	COG1177	transmembrane transport
BCV59_RS05550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCV59_RS05555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BCV59_RS05565	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCV59_RS05575	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCV59_RS05580	COG4763	Acyl-transferase
BCV59_RS05585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCV59_RS05590	COG1388	LysM domain
BCV59_RS05590	COG1376	ErfK ybiS ycfS ynhG family protein
BCV59_RS05600	COG1309	transcriptional regulator
BCV59_RS05605	COG3134	Outer membrane lipoprotein
BCV59_RS05610	COG1252	NADH dehydrogenase
BCV59_RS05630	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BCV59_RS05635	COG5633	Lipoprotein
BCV59_RS05640	COG0537	adenosine 5'-monophosphoramidase activity
BCV59_RS05645	COG4773	Receptor
BCV59_RS05650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS05650	COG1263	PTS System
BCV59_RS05655	COG0084	hydrolase, TatD family'
BCV59_RS05660	COG0470	DNA polymerase III
BCV59_RS05670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCV59_RS05675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV59_RS05680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV59_RS05690	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS05695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCV59_RS05715	COG1399	metal-binding, possibly nucleic acid-binding protein
BCV59_RS05720	COG0424	maF-like protein
BCV59_RS05725	COG0564	pseudouridine synthase activity
BCV59_RS05735	COG1530	ribonuclease E activity
BCV59_RS05740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCV59_RS05745	COG1256	bacterial-type flagellum assembly
BCV59_RS05750	COG3951	Flagellar rod assembly protein muramidase FlgJ
BCV59_RS05750	COG1705	Flagellar rod assembly protein muramidase FlgJ
BCV59_RS05765	COG4786	Flagellar basal body rod
BCV59_RS05770	COG4787	bacterial-type flagellum-dependent cell motility
BCV59_RS05775	COG1749	Flagellar hook protein flgE
BCV59_RS05780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BCV59_RS05785	COG1558	bacterial-type flagellum-dependent cell motility
BCV59_RS05790	COG1815	bacterial-type flagellum-dependent cell motility
BCV59_RS05795	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BCV59_RS05800	COG2747	anti-sigma28 factor FlgM
BCV59_RS05805	COG3418	PFAM FlgN family protein
BCV59_RS05810	COG0728	peptidoglycan biosynthetic process
BCV59_RS05825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV59_RS05835	COG2999	glutathione oxidoreductase activity
BCV59_RS05870	COG3038	cytochrome b561
BCV59_RS05875	COG2353	YceI-like domain
BCV59_RS05885	COG1560	Kdo2-lipid A biosynthetic process
BCV59_RS05905	COG5645	(Lipo)protein
BCV59_RS05910	COG2943	transferase activity, transferring hexosyl groups
BCV59_RS05935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV59_RS05940	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCV59_RS05970	COG2197	response regulator
BCV59_RS05985	COG1462	curli production assembly transport component CsgG
BCV59_RS05995	COG3381	protein complex oligomerization
BCV59_RS06030	COG3706	GGDEF domain
BCV59_RS06040	COG1649	PFAM Uncharacterised BCR, COG1649
BCV59_RS06040	COG0726	polysaccharide deacetylase
BCV59_RS06045	COG1215	transferase activity, transferring glycosyl groups
BCV59_RS06050	COG3658	cytochrome
BCV59_RS06055	COG1702	phosphate starvation-inducible protein PhoH
BCV59_RS06065	COG2822	iron ion transport
BCV59_RS06080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV59_RS06090	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BCV59_RS06090	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BCV59_RS06090	COG0506	proline dehydrogenase activity
BCV59_RS06095	COG1309	transcriptional regulator
BCV59_RS06105	COG1335	isochorismatase
BCV59_RS06130	COG2233	PERMEase
BCV59_RS06135	COG3729	General stress protein
BCV59_RS06180	COG0243	molybdopterin cofactor binding
BCV59_RS06185	COG3005	denitrification pathway
BCV59_RS06190	COG0745	RESPONSE REGULATOR receiver
BCV59_RS06195	COG1879	ABC-type sugar transport system periplasmic component
BCV59_RS06200	COG0784	Response regulator, receiver
BCV59_RS06200	COG2198	Histidine kinase
BCV59_RS06200	COG2205	protein histidine kinase activity
BCV59_RS06205	COG0348	domain, Protein
BCV59_RS06220	COG1278	Cold shock
BCV59_RS06225	COG1278	Cold shock
BCV59_RS06245	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV59_RS06250	COG1596	polysaccharide export
BCV59_RS06255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCV59_RS06260	COG3206	protein involved in exopolysaccharide biosynthesis
BCV59_RS06260	COG0489	protein tyrosine kinase activity
BCV59_RS06275	COG1294	oxidase, subunit
BCV59_RS06280	COG1271	oxidase subunit
BCV59_RS06290	COG1999	signal sequence binding
BCV59_RS06295	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCV59_RS06300	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BCV59_RS06305	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BCV59_RS06310	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BCV59_RS06345	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS06450	COG4220	transposase activity
BCV59_RS06475	COG3772	lysozyme
BCV59_RS06530	COG2207	Transcriptional regulator
BCV59_RS06545	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BCV59_RS06550	COG1403	HNH endonuclease
BCV59_RS06655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS06690	COG0670	Belongs to the BI1 family
BCV59_RS06695	COG2920	part of a sulfur-relay system
BCV59_RS06700	COG1254	Belongs to the acylphosphatase family
BCV59_RS06715	COG1832	CoA-binding protein
BCV59_RS06735	COG0210	DNA helicase
BCV59_RS06740	COG3304	Inner membrane component domain
BCV59_RS06745	COG1289	transmembrane transporter activity
BCV59_RS06750	COG3070	regulator of competence-specific genes
BCV59_RS06765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BCV59_RS06765	COG2885	chlorophyll binding
BCV59_RS06775	COG1067	ATP-dependent peptidase activity
BCV59_RS06785	COG3130	regulation of translation
BCV59_RS06790	COG3009	Protein conserved in bacteria
BCV59_RS06795	COG3008	intermembrane lipid transfer
BCV59_RS06795	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV59_RS06800	COG2995	paraquat-inducible protein a
BCV59_RS06805	COG0488	(ABC) transporter
BCV59_RS06815	COG0633	Ferredoxin
BCV59_RS06815	COG3217	Mosc domain protein beta barrel domain protein
BCV59_RS06830	COG3121	Chaperone
BCV59_RS06835	COG3539	Fimbrial protein
BCV59_RS06840	COG3539	Fimbrial protein
BCV59_RS06845	COG3539	Fimbrial protein
BCV59_RS06850	COG3188	usher protein
BCV59_RS06855	COG3121	Chaperone
BCV59_RS06860	COG3539	Fimbrial protein
BCV59_RS06865	COG0431	NADPH-dependent FMN reductase
BCV59_RS06870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCV59_RS06880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV59_RS06890	COG0308	aminopeptidase N
BCV59_RS06915	COG1448	Aminotransferase
BCV59_RS06920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV59_RS06925	COG3108	Peptidase M15
BCV59_RS06930	COG2989	Protein conserved in bacteria
BCV59_RS06940	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BCV59_RS06950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCV59_RS06955	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCV59_RS06960	COG3173	Aminoglycoside phosphotransferase
BCV59_RS06975	COG3214	Protein conserved in bacteria
BCV59_RS06985	COG1132	(ABC) transporter
BCV59_RS06990	COG0658	competence protein
BCV59_RS06990	COG2333	competence protein COMEC
BCV59_RS07000	COG0539	negative regulation of cytoplasmic translation
BCV59_RS07010	COG0501	Belongs to the peptidase M48B family
BCV59_RS07025	COG2323	membrane
BCV59_RS07030	COG1944	ATP diphosphatase activity
BCV59_RS07035	COG2116	formate transmembrane transporter activity
BCV59_RS07040	COG1882	Formate acetyltransferase
BCV59_RS07045	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCV59_RS07050	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCV59_RS07055	COG0583	DNA-binding transcription factor activity
BCV59_RS07060	COG0531	amino acid
BCV59_RS07070	COG1335	isochorismatase
BCV59_RS07075	COG3302	dmso reductase anchor subunit
BCV59_RS07080	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS07085	COG0243	molybdopterin cofactor binding
BCV59_RS07095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCV59_RS07110	COG1522	sequence-specific DNA binding
BCV59_RS07115	COG0492	ferredoxin-NADP+ reductase activity
BCV59_RS07120	COG4988	ABC transporter
BCV59_RS07125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCV59_RS07145	COG0542	response to heat
BCV59_RS07155	COG1278	Cold shock
BCV59_RS07160	COG0577	efflux transmembrane transporter activity
BCV59_RS07160	COG1136	(ABC) transporter
BCV59_RS07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV59_RS07170	COG2990	Protein conserved in bacteria
BCV59_RS07175	COG3593	DNA synthesis involved in DNA repair
BCV59_RS07190	COG2431	L-lysine efflux transmembrane transporter activity
BCV59_RS07200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV59_RS07205	COG0028	Belongs to the TPP enzyme family
BCV59_RS07210	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BCV59_RS07215	COG0702	epimerase
BCV59_RS07220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV59_RS07225	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCV59_RS07240	COG1126	abc transporter atp-binding protein
BCV59_RS07245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS07250	COG4215	(ABC) transporter
BCV59_RS07255	COG4160	amino acid transport
BCV59_RS07260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS07275	COG1177	transmembrane transport
BCV59_RS07280	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCV59_RS07285	COG3842	ATPase activity
BCV59_RS07290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCV59_RS07310	COG0778	Nitroreductase
BCV59_RS07320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCV59_RS07335	COG3226	Transcriptional regulator
BCV59_RS07340	COG0738	Major facilitator superfamily
BCV59_RS07345	COG0561	phosphatase activity
BCV59_RS07355	COG2814	Major facilitator Superfamily
BCV59_RS07360	COG0671	phosphoesterase, PA-phosphatase related
BCV59_RS07365	COG1349	DNA-binding transcription factor activity
BCV59_RS07370	COG1686	Belongs to the peptidase S11 family
BCV59_RS07375	COG0625	glutathione transferase activity
BCV59_RS07380	COG2133	pyrroloquinoline quinone binding
BCV59_RS07395	COG2199	diguanylate cyclase activity
BCV59_RS07400	COG2200	EAL domain
BCV59_RS07430	COG0303	'Molybdopterin
BCV59_RS07435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV59_RS07440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV59_RS07445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCV59_RS07450	COG1882	Formate acetyltransferase
BCV59_RS07455	COG0561	phosphatase activity
BCV59_RS07465	COG0488	(ABC) transporter
BCV59_RS07470	COG1376	ErfK ybiS ycfS ynhG family protein
BCV59_RS07475	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCV59_RS07480	COG1321	iron dependent repressor
BCV59_RS07490	COG2194	sulfuric ester hydrolase activity
BCV59_RS07495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BCV59_RS07500	COG5006	permease, DMT superfamily
BCV59_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS07520	COG0765	amino acid transport
BCV59_RS07525	COG1126	abc transporter atp-binding protein
BCV59_RS07535	COG0668	transmembrane transport
BCV59_RS07550	COG4774	siderophore transport
BCV59_RS07560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV59_RS07570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BCV59_RS07575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV59_RS07580	COG1199	ATP-dependent helicase activity
BCV59_RS07585	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
BCV59_RS07590	COG0513	Belongs to the DEAD box helicase family
BCV59_RS07595	COG1309	transcriptional regulator
BCV59_RS07605	COG1131	(ABC) transporter
BCV59_RS07610	COG0842	Transport permease protein
BCV59_RS07615	COG0842	Transport permease protein
BCV59_RS07625	COG3568	Endonuclease Exonuclease Phosphatase
BCV59_RS07630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV59_RS07635	COG0392	lysyltransferase activity
BCV59_RS07640	COG0670	Belongs to the BI1 family
BCV59_RS07645	COG0670	Belongs to the BI1 family
BCV59_RS07650	COG0314	molybdopterin synthase activity
BCV59_RS07655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BCV59_RS07665	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCV59_RS07675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BCV59_RS07685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCV59_RS07690	COG2226	methyltransferase
BCV59_RS07705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCV59_RS07710	COG1881	PFAM PEBP family protein
BCV59_RS07760	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS07785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV59_RS07865	COG0582	viral genome integration into host DNA
BCV59_RS07870	COG4677	pectinesterase activity
BCV59_RS07875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCV59_RS07880	COG0471	metal ion transport
BCV59_RS07885	COG2828	Protein conserved in bacteria
BCV59_RS07890	COG0583	DNA-binding transcription factor activity
BCV59_RS07900	COG0561	phosphatase activity
BCV59_RS07905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BCV59_RS07910	COG4149	molybdate abc transporter
BCV59_RS07915	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCV59_RS07925	COG2005	Transcriptional regulator
BCV59_RS07925	COG3585	molybdate ion transport
BCV59_RS07930	COG1119	ATPase activity
BCV59_RS07935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCV59_RS07940	COG1085	galactose-1-phosphate uridylyltransferase
BCV59_RS07950	COG2017	converts alpha-aldose to the beta-anomer
BCV59_RS07960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV59_RS07975	COG1230	cation diffusion facilitator family transporter
BCV59_RS07980	COG3201	nicotinamide mononucleotide transporter
BCV59_RS08035	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BCV59_RS08040	COG2885	chlorophyll binding
BCV59_RS08050	COG3064	Membrane
BCV59_RS08055	COG0848	biopolymer transport protein
BCV59_RS08060	COG0811	peptide transport
BCV59_RS08065	COG0824	Thioesterase
BCV59_RS08070	COG3790	cyd operon protein YbgE
BCV59_RS08075	COG4890	Cyd operon protein YbgT
BCV59_RS08080	COG1294	oxidase, subunit
BCV59_RS08085	COG1271	oxidase subunit
BCV59_RS08095	COG0383	alpha-mannosidase activity
BCV59_RS08110	COG0383	alpha-mannosidase activity
BCV59_RS08120	COG2188	Transcriptional regulator
BCV59_RS08125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV59_RS08135	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV59_RS08140	COG0567	Dehydrogenase, E1 component
BCV59_RS08150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCV59_RS08155	COG1053	succinate dehydrogenase
BCV59_RS08160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BCV59_RS08165	COG2009	succinate dehydrogenase
BCV59_RS08175	COG0372	Belongs to the citrate synthase family
BCV59_RS08185	COG3188	usher protein
BCV59_RS08190	COG3121	Chaperone
BCV59_RS08195	COG3539	Fimbrial protein
BCV59_RS08200	COG3180	Ammonia monooxygenase
BCV59_RS08215	COG1984	allophanate hydrolase subunit 2
BCV59_RS08220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCV59_RS08225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCV59_RS08235	COG0415	Belongs to the DNA photolyase family
BCV59_RS08240	COG3272	Protein of unknown function (DUF1722)
BCV59_RS08245	COG5433	transposase activity
BCV59_RS08255	COG5433	transposase activity
BCV59_RS08265	COG3209	COG3209 Rhs family protein
BCV59_RS08265	COG3209	COG3209 Rhs family protein
BCV59_RS08295	COG2205	protein histidine kinase activity
BCV59_RS08300	COG0745	RESPONSE REGULATOR receiver
BCV59_RS08310	COG1982	Orn Lys Arg decarboxylase major
BCV59_RS08315	COG0531	amino acid
BCV59_RS08320	COG0033	Phosphoglucomutase
BCV59_RS08325	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BCV59_RS08330	COG0596	Alpha beta hydrolase
BCV59_RS08340	COG0716	FMN binding
BCV59_RS08355	COG0735	belongs to the Fur family
BCV59_RS08375	COG2190	(PTS) system
BCV59_RS08375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS08375	COG1263	PTS System
BCV59_RS08385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV59_RS08390	COG1846	Transcriptional regulator
BCV59_RS08390	COG1940	carbohydrate kinase activity
BCV59_RS08395	COG0647	UMP catabolic process
BCV59_RS08400	COG0367	asparagine synthase
BCV59_RS08440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV59_RS08450	COG1702	phosphate starvation-inducible protein PhoH
BCV59_RS08460	COG4535	Mg2 and Co2 transporter CorC
BCV59_RS08465	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BCV59_RS08475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS08480	COG0765	amino acid transport
BCV59_RS08485	COG0765	amino acid transport
BCV59_RS08490	COG1126	abc transporter atp-binding protein
BCV59_RS08500	COG0443	Heat shock 70 kDa protein
BCV59_RS08505	COG2214	Heat shock protein DnaJ domain protein
BCV59_RS08510	COG2214	Heat shock protein DnaJ domain protein
BCV59_RS08515	COG2214	Heat shock protein DnaJ domain protein
BCV59_RS08525	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BCV59_RS08530	COG2888	peptidyl-tyrosine sulfation
BCV59_RS08545	COG1466	dna polymerase III delta subunit
BCV59_RS08555	COG0406	alpha-ribazole phosphatase activity
BCV59_RS08560	COG0799	negative regulation of ribosome biogenesis
BCV59_RS08570	COG0768	penicillin binding
BCV59_RS08575	COG0772	Belongs to the SEDS family
BCV59_RS08580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCV59_RS08585	COG1686	Belongs to the peptidase S11 family
BCV59_RS08605	COG0583	DNA-binding transcription factor activity
BCV59_RS08615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCV59_RS08620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV59_RS08640	COG3069	C4-dicarboxylate transmembrane transporter activity
BCV59_RS08645	COG4565	transcriptional regulatory protein
BCV59_RS08650	COG3290	protein histidine kinase activity
BCV59_RS08655	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BCV59_RS08665	COG2301	Belongs to the HpcH HpaI aldolase family
BCV59_RS08670	COG3051	citrate lyase alpha subunit
BCV59_RS08685	COG0471	metal ion transport
BCV59_RS08690	COG3719	Belongs to the RNase T2 family
BCV59_RS08695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV59_RS08705	COG1063	alcohol dehydrogenase
BCV59_RS08710	COG0589	response to stress
BCV59_RS08715	COG3634	alkyl hydroperoxide reductase activity
BCV59_RS08720	COG0450	alkyl hydroperoxide reductase
BCV59_RS08725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV59_RS08730	COG0583	DNA-binding transcription factor activity
BCV59_RS08735	COG3969	phosphoadenosine phosphosulfate
BCV59_RS08740	COG1475	DNA binding
BCV59_RS08745	COG0436	Aminotransferase
BCV59_RS08750	COG0371	Dehydrogenase
BCV59_RS08755	COG2879	small protein
BCV59_RS08760	COG1966	Carbon starvation protein
BCV59_RS08765	COG2050	protein possibly involved in aromatic compounds catabolism
BCV59_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS08775	COG1535	isochorismatase
BCV59_RS08775	COG3433	isochorismatase activity
BCV59_RS08780	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCV59_RS08785	COG1169	isochorismate synthase
BCV59_RS08790	COG4592	Periplasmic binding protein
BCV59_RS08800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV59_RS08805	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV59_RS08810	COG1120	ATPase activity
BCV59_RS08815	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BCV59_RS08820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV59_RS08820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BCV59_RS08825	COG3251	PFAM MbtH domain protein
BCV59_RS08830	COG2382	esterase
BCV59_RS08835	COG4771	TonB-dependent receptor
BCV59_RS08840	COG2977	Belongs to the P-Pant transferase superfamily
BCV59_RS08870	COG2315	Protein conserved in bacteria
BCV59_RS08875	COG0778	Nitroreductase
BCV59_RS08880	COG0668	transmembrane transport
BCV59_RS08885	COG1113	amino acid transport
BCV59_RS08890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV59_RS08895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV59_RS08900	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV59_RS08905	COG1538	Outer membrane efflux protein
BCV59_RS08910	COG0745	RESPONSE REGULATOR receiver
BCV59_RS08915	COG5002	protein histidine kinase activity
BCV59_RS08920	COG3501	Rhs element vgr protein
BCV59_RS08935	COG4104	PAAR repeat-containing protein
BCV59_RS08935	COG3209	COG3209 Rhs family protein
BCV59_RS08950	COG5433	transposase activity
BCV59_RS08955	COG1215	transferase activity, transferring glycosyl groups
BCV59_RS08960	COG4783	chaperone-mediated protein folding
BCV59_RS08970	COG2207	Transcriptional regulator
BCV59_RS08980	COG2197	response regulator
BCV59_RS08985	COG3539	Fimbrial protein
BCV59_RS08990	COG3539	Fimbrial protein
BCV59_RS08995	COG3188	usher protein
BCV59_RS09000	COG3121	Chaperone
BCV59_RS09005	COG3539	Fimbrial protein
BCV59_RS09015	COG2501	S4 domain
BCV59_RS09020	COG1988	membrane-bound metal-dependent
BCV59_RS09030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCV59_RS09040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCV59_RS09045	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCV59_RS09050	COG0549	Belongs to the carbamate kinase family
BCV59_RS09060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV59_RS09065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV59_RS09070	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BCV59_RS09075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV59_RS09080	COG3257	ureidoglycine aminohydrolase activity
BCV59_RS09085	COG1929	Belongs to the glycerate kinase type-1 family
BCV59_RS09090	COG2233	PERMEase
BCV59_RS09100	COG1953	Uracil, thiamine, allantoin
BCV59_RS09105	COG2084	Dehydrogenase
BCV59_RS09110	COG3622	Belongs to the hyi family
BCV59_RS09115	COG3960	tartronate-semialdehyde synthase activity
BCV59_RS09120	COG1414	Transcriptional regulator
BCV59_RS09130	COG0583	DNA-binding transcription factor activity
BCV59_RS09140	COG2801	Transposase and inactivated derivatives
BCV59_RS09160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BCV59_RS09165	COG4181	ATPase activity
BCV59_RS09170	COG2755	lipolytic protein G-D-S-L family
BCV59_RS09175	COG0300	oxidoreductase activity
BCV59_RS09180	COG3118	belongs to the thioredoxin family
BCV59_RS09185	COG0390	transport system, permease component
BCV59_RS09190	COG4619	ABC transporter
BCV59_RS09195	COG0330	HflC and HflK could
BCV59_RS09205	COG0789	Transcriptional regulator
BCV59_RS09210	COG0531	amino acid
BCV59_RS09220	COG2217	Heavy metal translocating P-type atpase
BCV59_RS09225	COG3093	addiction module antidote protein HigA
BCV59_RS09230	COG3735	TraB family
BCV59_RS09235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCV59_RS09240	COG0737	Belongs to the 5'-nucleotidase family
BCV59_RS09245	COG2223	nitrite transmembrane transporter activity
BCV59_RS09250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV59_RS09250	COG4651	solute:proton antiporter activity
BCV59_RS09255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS09290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCV59_RS09300	COG2832	Protein of unknown function (DUF454)
BCV59_RS09305	COG3923	Primosomal replication protein n
BCV59_RS09320	COG1196	nuclear chromosome segregation
BCV59_RS09320	COG3264	Mechanosensitive ion channel
BCV59_RS09325	COG1309	transcriptional regulator
BCV59_RS09330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV59_RS09335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV59_RS09350	COG0110	maltose O-acetyltransferase activity
BCV59_RS09360	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV59_RS09375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV59_RS09380	COG5507	3-demethylubiquinone-9 3-methyltransferase
BCV59_RS09390	COG3695	enzyme binding
BCV59_RS09395	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BCV59_RS09400	COG1946	Acyl-CoA thioesterase
BCV59_RS09405	COG0004	ammonium transporteR
BCV59_RS09415	COG1132	(ABC) transporter
BCV59_RS09420	COG1132	(ABC) transporter
BCV59_RS09425	COG1522	sequence-specific DNA binding
BCV59_RS09435	COG4533	DNA binding
BCV59_RS09445	COG0824	Thioesterase
BCV59_RS09450	COG1555	photosystem II stabilization
BCV59_RS09455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV59_RS09460	COG0776	regulation of translation
BCV59_RS09490	COG0271	Belongs to the BolA IbaG family
BCV59_RS09495	COG3056	Lipoprotein
BCV59_RS09500	COG2223	nitrite transmembrane transporter activity
BCV59_RS09505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV59_RS09510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCV59_RS09515	COG1845	cytochrome c oxidase, subunit III
BCV59_RS09520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCV59_RS09545	COG2814	Major facilitator Superfamily
BCV59_RS09555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCV59_RS09560	COG0693	protein deglycase activity
BCV59_RS09575	COG0142	geranyltranstransferase activity
BCV59_RS09585	COG0667	Aldo Keto reductase
BCV59_RS09590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCV59_RS09595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCV59_RS09610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV59_RS09610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV59_RS09620	COG4238	major outer membrane lipoprotein
BCV59_RS09625	COG3248	Nucleoside-binding outer membrane protein
BCV59_RS09635	COG1403	HNH endonuclease
BCV59_RS09640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV59_RS09645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV59_RS09650	COG1862	Preprotein translocase
BCV59_RS09670	COG0366	Alpha amylase catalytic
BCV59_RS09675	COG1113	amino acid transport
BCV59_RS09680	COG1114	Component of the transport system for branched-chain amino acids
BCV59_RS09685	COG5002	protein histidine kinase activity
BCV59_RS09690	COG0745	RESPONSE REGULATOR receiver
BCV59_RS09695	COG0420	3'-5' exonuclease activity
BCV59_RS09700	COG0419	ATPase involved in DNA repair
BCV59_RS09705	COG2814	Major facilitator Superfamily
BCV59_RS09710	COG1940	carbohydrate kinase activity
BCV59_RS09730	COG4126	flavin adenine dinucleotide binding
BCV59_RS09755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCV59_RS09760	COG3706	GGDEF domain
BCV59_RS09770	COG1785	Belongs to the alkaline phosphatase family
BCV59_RS09785	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCV59_RS09810	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BCV59_RS09820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV59_RS09825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV59_RS09830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV59_RS09835	COG3468	outer membrane autotransporter barrel domain protein
BCV59_RS09840	COG0113	porphobilinogen synthase activity
BCV59_RS09860	COG4521	taurine ABC transporter
BCV59_RS09865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCV59_RS09870	COG1215	transferase activity, transferring glycosyl groups
BCV59_RS09900	COG3122	Protein conserved in bacteria
BCV59_RS09905	COG2814	Major facilitator Superfamily
BCV59_RS09940	COG1414	Transcriptional regulator
BCV59_RS09945	COG1609	Transcriptional regulator
BCV59_RS09955	COG2223	nitrite transmembrane transporter activity
BCV59_RS09960	COG0110	maltose O-acetyltransferase activity
BCV59_RS09965	COG2807	transmembrane transport
BCV59_RS09975	COG0288	reversible hydration of carbon dioxide
BCV59_RS09980	COG0583	DNA-binding transcription factor activity
BCV59_RS09985	COG0402	S-adenosylhomocysteine deaminase activity
BCV59_RS09990	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCV59_RS09995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV59_RS10000	COG2079	MmgE PrpD family protein
BCV59_RS10005	COG0372	Belongs to the citrate synthase family
BCV59_RS10010	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCV59_RS10015	COG3829	transcription factor binding
BCV59_RS10025	COG1280	lysine exporter protein (LysE YggA)
BCV59_RS10040	COG1064	alcohol dehydrogenase
BCV59_RS10045	COG0402	S-adenosylhomocysteine deaminase activity
BCV59_RS10050	COG0549	Belongs to the carbamate kinase family
BCV59_RS10055	COG1304	FMN binding
BCV59_RS10060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV59_RS10070	COG0666	response to abiotic stimulus
BCV59_RS10080	COG0583	DNA-binding transcription factor activity
BCV59_RS10085	COG2771	luxR family
BCV59_RS10085	COG2200	EAL domain
BCV59_RS10095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCV59_RS10120	COG1556	Lactate utilization protein
BCV59_RS10125	COG1139	Iron-sulfur cluster binding protein
BCV59_RS10130	COG0247	lactate metabolic process
BCV59_RS10135	COG2207	Transcriptional regulator
BCV59_RS10150	COG3059	membrane
BCV59_RS10155	COG0656	L-ascorbic acid biosynthetic process
BCV59_RS10160	COG3708	Transcriptional regulator
BCV59_RS10160	COG2207	Transcriptional regulator
BCV59_RS10165	COG1388	LysM domain
BCV59_RS10170	COG0656	L-ascorbic acid biosynthetic process
BCV59_RS10175	COG0667	Aldo Keto reductase
BCV59_RS10220	COG3188	usher protein
BCV59_RS10230	COG3121	Chaperone
BCV59_RS10235	COG0727	PFAM Uncharacterised protein family (UPF0153)
BCV59_RS10250	COG0582	viral genome integration into host DNA
BCV59_RS10270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV59_RS10290	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCV59_RS10295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCV59_RS10305	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS10310	COG4372	Transposase
BCV59_RS10320	COG0454	-acetyltransferase
BCV59_RS10350	COG0791	NLP P60 protein
BCV59_RS10355	COG3077	Addiction module antitoxin, RelB DinJ family
BCV59_RS10360	COG3041	Addiction module toxin RelE StbE family
BCV59_RS10365	COG3034	peptidoglycan biosynthetic process
BCV59_RS10370	COG0121	glutamine amidotransferase
BCV59_RS10380	COG1960	acyl-CoA dehydrogenase activity
BCV59_RS10390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV59_RS10395	COG5433	transposase activity
BCV59_RS10410	COG5433	transposase activity
BCV59_RS10420	COG3209	COG3209 Rhs family protein
BCV59_RS10505	COG3157	Type VI secretion system effector, Hcp
BCV59_RS10510	COG4104	PAAR repeat-containing protein
BCV59_RS10530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS10540	COG2226	methyltransferase
BCV59_RS10550	COG1388	LysM domain
BCV59_RS10550	COG0741	lytic transglycosylase activity
BCV59_RS10555	COG2226	methyltransferase
BCV59_RS10565	COG0583	DNA-binding transcription factor activity
BCV59_RS10570	COG0656	L-ascorbic acid biosynthetic process
BCV59_RS10605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCV59_RS10610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCV59_RS10615	COG2011	ABC-type metal ion transport system permease component
BCV59_RS10620	COG1464	Belongs to the NlpA lipoprotein family
BCV59_RS10630	COG1720	tRNA m6t6A37 methyltransferase activity
BCV59_RS10640	COG0791	NLP P60 protein
BCV59_RS10645	COG0791	NLP P60 protein
BCV59_RS10650	COG3015	lipoprotein NlpE involved in copper resistance
BCV59_RS10655	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCV59_RS10660	COG4681	YaeQ
BCV59_RS10670	COG4568	rho-dependent transcription termination
BCV59_RS10680	COG0346	lactoylglutathione lyase activity
BCV59_RS10685	COG1982	Orn Lys Arg decarboxylase major
BCV59_RS10695	COG0587	DNA-directed DNA polymerase activity
BCV59_RS10720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV59_RS10725	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BCV59_RS10735	COG0750	zinc metalloprotease
BCV59_RS10740	COG0575	Belongs to the CDS family
BCV59_RS10745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCV59_RS10750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCV59_RS10775	COG0024	Methionine aminopeptidase
BCV59_RS10795	COG3835	regulator
BCV59_RS10800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV59_RS10815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV59_RS10820	COG2860	membrane
BCV59_RS10840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV59_RS10845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV59_RS10850	COG1120	ATPase activity
BCV59_RS10855	COG4774	siderophore transport
BCV59_RS10860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV59_RS10870	COG1643	Atp-dependent helicase
BCV59_RS10875	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCV59_RS10885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV59_RS10895	COG0617	tRNA 3'-terminal CCA addition
BCV59_RS10900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCV59_RS10905	COG3539	Fimbrial protein
BCV59_RS10910	COG3121	Chaperone
BCV59_RS10915	COG3188	usher protein
BCV59_RS10920	COG3539	Fimbrial protein
BCV59_RS10925	COG3539	Fimbrial protein
BCV59_RS10930	COG3539	Fimbrial protein
BCV59_RS10935	COG3539	Fimbrial protein
BCV59_RS10950	COG5464	transposase or invertase
BCV59_RS10960	COG0726	polysaccharide deacetylase
BCV59_RS10965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS10970	COG0842	Transport permease protein
BCV59_RS10975	COG1131	(ABC) transporter
BCV59_RS10980	COG0288	reversible hydration of carbon dioxide
BCV59_RS10985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCV59_RS10990	COG4993	Dehydrogenase
BCV59_RS10995	COG2132	Multicopper oxidase
BCV59_RS11020	COG1049	propionate catabolic process, 2-methylcitrate cycle
BCV59_RS11025	COG3064	Membrane
BCV59_RS11030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV59_RS11035	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV59_RS11040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BCV59_RS11045	COG2186	Transcriptional regulator
BCV59_RS11050	COG1113	amino acid transport
BCV59_RS11060	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCV59_RS11065	COG0157	Belongs to the NadC ModD family
BCV59_RS11075	COG4969	Belongs to the N-Me-Phe pilin family
BCV59_RS11080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV59_RS11085	COG1459	type II secretion system
BCV59_RS11095	COG0237	dephospho-CoA kinase activity
BCV59_RS11115	COG0494	nUDIX hydrolase
BCV59_RS11140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCV59_RS11145	COG0849	cell division
BCV59_RS11150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCV59_RS11155	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCV59_RS11170	COG0772	Belongs to the SEDS family
BCV59_RS11185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCV59_RS11190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCV59_RS11195	COG0768	penicillin binding
BCV59_RS11200	COG3116	cell division
BCV59_RS11215	COG1609	Transcriptional regulator
BCV59_RS11225	COG0440	acetolactate synthase activity
BCV59_RS11230	COG0028	Belongs to the TPP enzyme family
BCV59_RS11250	COG0473	3-isopropylmalate dehydrogenase activity
BCV59_RS11265	COG2814	Major facilitator Superfamily
BCV59_RS11280	COG4143	(ABC) transporter
BCV59_RS11285	COG1178	ABC-type Fe3 transport system permease component
BCV59_RS11295	COG0586	Pfam SNARE associated Golgi protein
BCV59_RS11300	COG4977	sequence-specific DNA binding
BCV59_RS11315	COG0235	Class ii aldolase
BCV59_RS11320	COG0417	DNA replication proofreading
BCV59_RS11330	COG0564	pseudouridine synthase activity
BCV59_RS11335	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BCV59_RS11340	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCV59_RS11345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV59_RS11370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCV59_RS11385	COG2271	Major facilitator Superfamily
BCV59_RS11390	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BCV59_RS11395	COG0644	oxidoreductase
BCV59_RS11450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCV59_RS11455	COG0505	Belongs to the CarA family
BCV59_RS11485	COG1047	Peptidyl-prolyl cis-trans
BCV59_RS11500	COG0196	riboflavin kinase activity
BCV59_RS11520	COG3188	usher protein
BCV59_RS11530	COG0583	DNA-binding transcription factor activity
BCV59_RS11560	COG4735	regulation of single-species biofilm formation
BCV59_RS11565	COG1584	GPR1 FUN34 yaaH family protein
BCV59_RS11570	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCV59_RS11580	COG1115	amino acid carrier protein
BCV59_RS11600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCV59_RS11610	COG0460	homoserine dehydrogenase
BCV59_RS11610	COG0527	aspartate kinase activity
BCV59_RS11620	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BCV59_RS11630	COG0745	RESPONSE REGULATOR receiver
BCV59_RS11635	COG4452	Inner membrane protein CreD
BCV59_RS11640	COG2205	protein histidine kinase activity
BCV59_RS11645	COG0745	RESPONSE REGULATOR receiver
BCV59_RS11650	COG3045	CreA protein
BCV59_RS11655	COG3708	Transcriptional regulator
BCV59_RS11655	COG2207	Transcriptional regulator
BCV59_RS11675	COG0741	lytic transglycosylase activity
BCV59_RS11680	COG0488	(ABC) transporter
BCV59_RS11690	COG3172	ATPase kinase involved in NAD metabolism
BCV59_RS11690	COG1056	cytidyltransferase-related domain
BCV59_RS11695	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCV59_RS11700	COG0560	Phosphoserine phosphatase
BCV59_RS11705	COG3726	membrane protein affecting hemolysin expression
BCV59_RS11745	COG1328	CTP reductase activity
BCV59_RS11750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCV59_RS11755	COG0084	hydrolase, TatD family'
BCV59_RS11760	COG4667	esterase of the alpha-beta hydrolase superfamily
BCV59_RS11770	COG2823	Periplasmic or secreted lipoprotein
BCV59_RS11790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCV59_RS11795	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCV59_RS11810	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCV59_RS11815	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS11835	COG1196	nuclear chromosome segregation
BCV59_RS11890	COG4220	transposase activity
BCV59_RS11900	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS11905	COG4372	Transposase
BCV59_RS11910	COG4220	transposase activity
BCV59_RS11935	COG1278	Cold shock
BCV59_RS11945	COG3772	lysozyme
BCV59_RS11960	COG1278	Cold shock
BCV59_RS11965	COG1278	Cold shock
BCV59_RS11975	COG0484	heat shock protein binding
BCV59_RS11980	COG1403	HNH endonuclease
BCV59_RS11990	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BCV59_RS11995	COG4725	Belongs to the MT-A70-like family
BCV59_RS12005	COG1846	Transcriptional regulator
BCV59_RS12025	COG4197	protein conserved in bacteria, prophage-related
BCV59_RS12030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV59_RS12050	COG5532	Uncharacterized conserved protein (DUF2303)
BCV59_RS12055	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BCV59_RS12060	COG0583	DNA-binding transcription factor activity
BCV59_RS12110	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
BCV59_RS12115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCV59_RS12130	COG0582	viral genome integration into host DNA
BCV59_RS12135	COG4974	Belongs to the 'phage' integrase family
BCV59_RS12150	COG3539	Fimbrial protein
BCV59_RS12155	COG3121	Chaperone
BCV59_RS12160	COG3188	usher protein
BCV59_RS12165	COG3539	Fimbrial protein
BCV59_RS12170	COG3539	Fimbrial protein
BCV59_RS12175	COG3539	Fimbrial protein
BCV59_RS12180	COG2610	gluconate transmembrane transporter activity
BCV59_RS12195	COG0246	Mannitol dehydrogenase
BCV59_RS12205	COG2186	Transcriptional regulator
BCV59_RS12245	COG0583	DNA-binding transcription factor activity
BCV59_RS12250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV59_RS12255	COG0700	Nucleoside recognition
BCV59_RS12260	COG3366	ferrous iron transmembrane transporter activity
BCV59_RS12270	COG0477	Major facilitator Superfamily
BCV59_RS12285	COG1924	4 iron, 4 sulfur cluster binding
BCV59_RS12290	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BCV59_RS12295	COG2733	membrane
BCV59_RS12300	COG2814	Major facilitator Superfamily
BCV59_RS12315	COG5457	Domain of unknown function (DUF1127)
BCV59_RS12325	COG0523	cobalamin synthesis protein
BCV59_RS12330	COG2879	small protein
BCV59_RS12335	COG1966	Carbon starvation protein
BCV59_RS12345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCV59_RS12350	COG2368	4-hydroxyphenylacetate
BCV59_RS12370	COG3971	2-oxopent-4-enoate hydratase activity
BCV59_RS12380	COG3384	dioxygenase
BCV59_RS12385	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS12390	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCV59_RS12395	COG1846	Transcriptional regulator
BCV59_RS12400	COG0840	transmembrane signaling receptor activity
BCV59_RS12405	COG2271	Major facilitator Superfamily
BCV59_RS12410	COG1802	Transcriptional regulator
BCV59_RS12415	COG1063	alcohol dehydrogenase
BCV59_RS12430	COG1484	DNA-dependent DNA replication
BCV59_RS12445	COG2966	Psort location CytoplasmicMembrane, score
BCV59_RS12450	COG2197	response regulator
BCV59_RS12455	COG2197	response regulator
BCV59_RS12460	COG4114	ferric iron reductase
BCV59_RS12490	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BCV59_RS12495	COG0456	acetyltransferase
BCV59_RS12500	COG1011	Hydrolase
BCV59_RS12525	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS12545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BCV59_RS12545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV59_RS12560	COG0328	RNA-DNA hybrid ribonuclease activity
BCV59_RS12600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCV59_RS12605	COG0464	growth
BCV59_RS12610	COG1404	Belongs to the peptidase S8 family
BCV59_RS12670	COG0582	viral genome integration into host DNA
BCV59_RS12680	COG1064	alcohol dehydrogenase
BCV59_RS12685	COG3265	gluconokinase activity
BCV59_RS12690	COG1063	alcohol dehydrogenase
BCV59_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS12700	COG2610	gluconate transmembrane transporter activity
BCV59_RS12705	COG1609	Transcriptional regulator
BCV59_RS12710	COG0433	COG0433 Predicted ATPase
BCV59_RS12715	COG0795	lipopolysaccharide-transporting ATPase activity
BCV59_RS12720	COG0795	lipopolysaccharide-transporting ATPase activity
BCV59_RS12730	COG2927	DNA polymerase III (CHI subunit)
BCV59_RS12735	COG0525	valine-tRNA ligase activity
BCV59_RS12740	COG4269	membrane
BCV59_RS12745	COG0456	acetyltransferase
BCV59_RS12750	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BCV59_RS12770	COG2731	YhcH YjgK YiaL family protein
BCV59_RS12775	COG1309	transcriptional regulator
BCV59_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS12785	COG0251	oxidation-reduction process
BCV59_RS12810	COG0251	oxidation-reduction process
BCV59_RS12815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCV59_RS12820	COG1609	Transcriptional regulator
BCV59_RS12825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS12825	COG1263	PTS System
BCV59_RS12830	COG0366	Alpha amylase catalytic
BCV59_RS12835	COG1328	CTP reductase activity
BCV59_RS12840	COG0602	queuosine metabolic process
BCV59_RS12845	COG3783	Cytochrome b(562)
BCV59_RS12850	COG0312	modulator of DNA gyrase
BCV59_RS12860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCV59_RS12870	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV59_RS12875	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV59_RS12885	COG1879	ABC-type sugar transport system periplasmic component
BCV59_RS12890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCV59_RS12895	COG2105	PFAM AIG2 family protein
BCV59_RS12900	COG2911	Protein conserved in bacteria
BCV59_RS12905	COG0729	surface antigen
BCV59_RS12920	COG1253	flavin adenine dinucleotide binding
BCV59_RS12930	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BCV59_RS12940	COG1218	3'(2'),5'-bisphosphate nucleotidase
BCV59_RS12945	COG0737	Belongs to the 5'-nucleotidase family
BCV59_RS12950	COG1733	regulation of RNA biosynthetic process
BCV59_RS12955	COG0702	epimerase
BCV59_RS12960	COG0697	spore germination
BCV59_RS12970	COG1113	amino acid transport
BCV59_RS12975	COG0545	Peptidyl-prolyl cis-trans isomerase
BCV59_RS12980	COG3061	Opacity-associated protein A
BCV59_RS12985	COG1309	transcriptional regulator
BCV59_RS13000	COG1024	Enoyl-CoA hydratase
BCV59_RS13005	COG4670	ketone body catabolic process
BCV59_RS13010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCV59_RS13015	COG2271	Major facilitator Superfamily
BCV59_RS13030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCV59_RS13055	COG3477	response to acidic pH
BCV59_RS13085	COG3037	sugar-specific permease SgaT UlaA
BCV59_RS13100	COG1073	alpha beta
BCV59_RS13105	COG3650	response to hydrogen peroxide
BCV59_RS13115	COG1960	acyl-CoA dehydrogenase activity
BCV59_RS13120	COG0754	glutathionylspermidine amidase activity
BCV59_RS13125	COG5463	Belongs to the UPF0441 family
BCV59_RS13130	COG3766	membrane
BCV59_RS13145	COG1842	Phage shock protein A
BCV59_RS13150	COG3789	protein conserved in bacteria
BCV59_RS13155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV59_RS13160	COG0557	exoribonuclease II activity
BCV59_RS13175	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BCV59_RS13180	COG0330	HflC and HflK could
BCV59_RS13185	COG0330	HflC and HflK could
BCV59_RS13190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCV59_RS13210	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV59_RS13215	COG0802	atpase or kinase
BCV59_RS13220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BCV59_RS13220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCV59_RS13225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCV59_RS13260	COG1511	domain protein
BCV59_RS13260	COG3264	Mechanosensitive ion channel
BCV59_RS13265	COG0531	amino acid
BCV59_RS13275	COG1053	succinate dehydrogenase
BCV59_RS13280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCV59_RS13295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV59_RS13300	COG3040	lipid binding
BCV59_RS13305	COG2076	Multidrug Resistance protein
BCV59_RS13310	COG5510	response to toxic substance
BCV59_RS13315	COG5510	response to toxic substance
BCV59_RS13325	COG1509	lysine 2,3-aminomutase activity
BCV59_RS13350	COG0531	amino acid
BCV59_RS13355	COG3030	protein affecting phage T7 exclusion by the F plasmid
BCV59_RS13360	COG1027	Aspartate ammonia-lyase
BCV59_RS13365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCV59_RS13380	COG1309	transcriptional regulator
BCV59_RS13390	COG0582	viral genome integration into host DNA
BCV59_RS13395	COG4372	Transposase
BCV59_RS13685	COG3710	Transcriptional regulator
BCV59_RS13690	COG0531	amino acid
BCV59_RS13695	COG1982	Orn Lys Arg decarboxylase major
BCV59_RS13700	COG3104	oligopeptide transport
BCV59_RS13705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCV59_RS13725	COG2388	GCN5-related N-acetyl-transferase
BCV59_RS13730	COG3592	Divergent 4Fe-4S mono-cluster
BCV59_RS13735	COG3290	protein histidine kinase activity
BCV59_RS13740	COG4565	transcriptional regulatory protein
BCV59_RS13750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCV59_RS13755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV59_RS13755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV59_RS13760	COG3647	Membrane
BCV59_RS13765	COG2211	Major facilitator Superfamily
BCV59_RS13770	COG1486	melibiose metabolic process
BCV59_RS13780	COG2169	Transcriptional regulator
BCV59_RS13785	COG1982	Orn Lys Arg decarboxylase major
BCV59_RS13790	COG2207	Transcriptional regulator
BCV59_RS13795	COG0531	amino acid
BCV59_RS13800	COG2194	sulfuric ester hydrolase activity
BCV59_RS13805	COG0745	RESPONSE REGULATOR receiver
BCV59_RS13810	COG0642	Histidine kinase
BCV59_RS13820	COG0477	Major facilitator Superfamily
BCV59_RS13830	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCV59_RS13835	COG2824	Alkylphosphonate utilization operon protein PhnA
BCV59_RS13840	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BCV59_RS13850	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BCV59_RS13855	COG3639	organic phosphonate transmembrane transporter activity
BCV59_RS13860	COG2188	Transcriptional regulator
BCV59_RS13865	COG3624	Phosphonate C-P lyase system protein PhnG
BCV59_RS13870	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BCV59_RS13875	COG3626	phosphonate metabolism
BCV59_RS13880	COG3627	carbon phosphorus lyase activity
BCV59_RS13885	COG4107	phosphonate C-P lyase system protein PhnK
BCV59_RS13890	COG4778	phosphonate C-P lyase system protein PhnL
BCV59_RS13895	COG3454	Phosphonate metabolism
BCV59_RS13900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BCV59_RS13905	COG0456	acetyltransferase
BCV59_RS13910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCV59_RS13920	COG0698	ribose 5-phosphate isomerase
BCV59_RS13925	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BCV59_RS13935	COG1566	PFAM secretion protein HlyD family protein
BCV59_RS13940	COG1289	transmembrane transporter activity
BCV59_RS13950	COG3383	formate dehydrogenase (NAD+) activity
BCV59_RS13955	COG3383	formate dehydrogenase (NAD+) activity
BCV59_RS13960	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BCV59_RS13965	COG1301	dicarboxylic acid transport
BCV59_RS13970	COG4235	cytochrome complex assembly
BCV59_RS13975	COG3088	subunit of a heme lyase
BCV59_RS13980	COG1138	Cytochrome C-type biogenesis protein
BCV59_RS13985	COG3301	Polysulphide reductase, NrfD
BCV59_RS13990	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS13995	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BCV59_RS14005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV59_RS14010	COG3162	membrane
BCV59_RS14020	COG1357	PFAM Pentapeptide repeats (8 copies)
BCV59_RS14025	COG0025	NhaP-type Na H and K H
BCV59_RS14030	COG2252	PERMEase
BCV59_RS14035	COG0789	Transcriptional regulator
BCV59_RS14040	COG2207	Transcriptional regulator
BCV59_RS14045	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV59_RS14055	COG0629	single-stranded DNA binding
BCV59_RS14060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCV59_RS14065	COG2315	Protein conserved in bacteria
BCV59_RS14070	COG0432	Pfam Uncharacterised protein family UPF0047
BCV59_RS14075	COG3700	Belongs to the class B bacterial acid phosphatase family
BCV59_RS14085	COG1448	Aminotransferase
BCV59_RS14090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCV59_RS14095	COG0305	Participates in initiation and elongation during chromosome replication
BCV59_RS14100	COG0604	alcohol dehydrogenase
BCV59_RS14110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV59_RS14155	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS14180	COG5532	Uncharacterized conserved protein (DUF2303)
BCV59_RS14185	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BCV59_RS14240	COG0735	belongs to the Fur family
BCV59_RS14245	COG3237	CsbD-like
BCV59_RS14250	COG0534	Mate efflux family protein
BCV59_RS14260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV59_RS14300	COG3842	ATPase activity
BCV59_RS14310	COG2182	Extracellular solute-binding protein
BCV59_RS14315	COG1175	transmembrane transport
BCV59_RS14320	COG3833	ABC-type maltose transport systems, permease component
BCV59_RS14325	COG0477	Major facilitator Superfamily
BCV59_RS14325	COG2814	Major facilitator Superfamily
BCV59_RS14345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV59_RS14370	COG0527	aspartate kinase activity
BCV59_RS14430	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCV59_RS14435	COG0646	methionine synthase
BCV59_RS14435	COG1410	methionine synthase
BCV59_RS14440	COG1414	Transcriptional regulator
BCV59_RS14455	COG2224	Isocitrate lyase
BCV59_RS14460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCV59_RS14470	COG0456	acetyltransferase
BCV59_RS14500	COG0151	Belongs to the GarS family
BCV59_RS14505	COG2204	response regulator
BCV59_RS14510	COG4191	Histidine kinase
BCV59_RS14515	COG3678	ATP-independent chaperone mediated protein folding
BCV59_RS14530	COG3068	Protein conserved in bacteria
BCV59_RS14565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV59_RS14570	COG2104	thiamine diphosphate biosynthetic process
BCV59_RS14580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCV59_RS14620	COG0250	Participates in transcription elongation, termination and antitermination
BCV59_RS14625	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCV59_RS14665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BCV59_RS14665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BCV59_RS14700	COG4206	TonB-dependent receptor
BCV59_RS14725	COG0583	DNA-binding transcription factor activity
BCV59_RS14740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCV59_RS14755	COG2194	sulfuric ester hydrolase activity
BCV59_RS14760	COG2207	Transcriptional regulator
BCV59_RS14765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS14770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCV59_RS14775	COG1882	Formate acetyltransferase
BCV59_RS14780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS14785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS14790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS14790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV59_RS14790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS14795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV59_RS14800	COG0371	Dehydrogenase
BCV59_RS14810	COG3738	Protein conserved in bacteria
BCV59_RS14815	COG0697	spore germination
BCV59_RS14825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCV59_RS14835	COG0527	aspartate kinase activity
BCV59_RS14835	COG0460	homoserine dehydrogenase
BCV59_RS14840	COG0626	cystathionine gamma-synthase activity
BCV59_RS14850	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BCV59_RS14870	COG3209	COG3209 Rhs family protein
BCV59_RS14870	COG3209	COG3209 Rhs family protein
BCV59_RS14880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCV59_RS14885	COG1609	Transcriptional regulator
BCV59_RS14890	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCV59_RS14905	COG1575	Belongs to the MenA family. Type 1 subfamily
BCV59_RS14920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCV59_RS14930	COG1494	fructose-1,6-bisphosphatase
BCV59_RS14940	COG0589	response to stress
BCV59_RS14945	COG3691	Protein conserved in bacteria
BCV59_RS14950	COG3152	Membrane
BCV59_RS14970	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BCV59_RS14985	COG3678	ATP-independent chaperone mediated protein folding
BCV59_RS14990	COG0745	RESPONSE REGULATOR receiver
BCV59_RS14995	COG2205	protein histidine kinase activity
BCV59_RS15000	COG2258	MOSC domain
BCV59_RS15015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV59_RS15060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS15065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS15065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS15070	COG1363	Peptidase, m42
BCV59_RS15075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS15075	COG3711	transcriptional antiterminator
BCV59_RS15090	COG0243	molybdopterin cofactor binding
BCV59_RS15090	COG3383	formate dehydrogenase (NAD+) activity
BCV59_RS15095	COG0243	molybdopterin cofactor binding
BCV59_RS15095	COG3383	formate dehydrogenase (NAD+) activity
BCV59_RS15100	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS15105	COG2864	formate dehydrogenase
BCV59_RS15115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BCV59_RS15120	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BCV59_RS15125	COG0456	acetyltransferase
BCV59_RS15140	COG1011	Hydrolase
BCV59_RS15145	COG1349	DNA-binding transcription factor activity
BCV59_RS15150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS15155	COG2084	Dehydrogenase
BCV59_RS15160	COG3684	Belongs to the aldolase LacD family
BCV59_RS15170	COG2017	converts alpha-aldose to the beta-anomer
BCV59_RS15175	COG1501	Belongs to the glycosyl hydrolase 31 family
BCV59_RS15180	COG2211	Major facilitator Superfamily
BCV59_RS15185	COG2211	Major facilitator Superfamily
BCV59_RS15190	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCV59_RS15195	COG2271	Major facilitator Superfamily
BCV59_RS15200	COG1082	Xylose isomerase domain protein TIM barrel
BCV59_RS15205	COG2188	Transcriptional regulator
BCV59_RS15210	COG1217	gtp-binding protein TYPA
BCV59_RS15220	COG0174	glutamine synthetase
BCV59_RS15225	COG3852	Histidine kinase
BCV59_RS15230	COG2204	response regulator
BCV59_RS15240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV59_RS15255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCV59_RS15255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCV59_RS15270	COG0204	Acyl-transferase
BCV59_RS15275	COG5339	Protein conserved in bacteria
BCV59_RS15280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV59_RS15285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCV59_RS15290	COG3084	Protein conserved in bacteria
BCV59_RS15295	COG0746	molybdenum cofactor guanylyltransferase activity
BCV59_RS15300	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCV59_RS15330	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BCV59_RS15335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCV59_RS15340	COG1739	Uncharacterized protein family UPF0029
BCV59_RS15360	COG0543	2 iron, 2 sulfur cluster binding
BCV59_RS15365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BCV59_RS15370	COG0250	Participates in transcription elongation, termination and antitermination
BCV59_RS15380	COG0805	protein transport
BCV59_RS15385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCV59_RS15390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCV59_RS15400	COG3165	ubiquinone biosynthetic process from chorismate
BCV59_RS15410	COG1322	Protein conserved in bacteria
BCV59_RS15415	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BCV59_RS15420	COG0412	Dienelactone hydrolase
BCV59_RS15430	COG0583	DNA-binding transcription factor activity
BCV59_RS15435	COG0697	spore germination
BCV59_RS15440	COG0561	phosphatase activity
BCV59_RS15445	COG2267	carboxylic ester hydrolase activity
BCV59_RS15450	COG1280	lysine exporter protein (LysE YggA)
BCV59_RS15455	COG1280	lysine exporter protein (LysE YggA)
BCV59_RS15460	COG0514	ATP-dependent DNA helicase (RecQ)
BCV59_RS15465	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BCV59_RS15470	COG2050	protein possibly involved in aromatic compounds catabolism
BCV59_RS15475	COG2962	Rard protein
BCV59_RS15500	COG0598	Magnesium transport protein CorA
BCV59_RS15510	COG3698	Phosphodiester glycosidase
BCV59_RS15515	COG0210	DNA helicase
BCV59_RS15520	COG1011	Hydrolase
BCV59_RS15530	COG3159	Protein conserved in bacteria
BCV59_RS15540	COG5567	small periplasmic lipoprotein
BCV59_RS15550	COG3072	Adenylate cyclase
BCV59_RS15560	COG1587	Uroporphyrinogen-III synthase
BCV59_RS15565	COG2959	enzyme of heme biosynthesis
BCV59_RS15570	COG3071	HemY protein
BCV59_RS15575	COG3119	arylsulfatase activity
BCV59_RS15580	COG0641	radical SAM
BCV59_RS15605	COG1113	amino acid transport
BCV59_RS15625	COG2244	polysaccharide biosynthetic process
BCV59_RS15630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCV59_RS15635	COG0456	acetyltransferase
BCV59_RS15640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCV59_RS15645	COG1088	dTDP-glucose 4,6-dehydratase activity
BCV59_RS15650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCV59_RS15655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCV59_RS15660	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BCV59_RS15665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCV59_RS15675	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCV59_RS15685	COG3118	belongs to the thioredoxin family
BCV59_RS15700	COG0210	DNA helicase
BCV59_RS15710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV59_RS15720	COG0583	DNA-binding transcription factor activity
BCV59_RS15725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCV59_RS15735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV59_RS15740	COG3978	acetolactate synthase activity
BCV59_RS15760	COG0606	chelatase, subunit chli
BCV59_RS15765	COG3085	chromosome segregation
BCV59_RS15805	COG2186	Transcriptional regulator
BCV59_RS15810	COG0477	Major facilitator Superfamily
BCV59_RS15815	COG1609	Transcriptional regulator
BCV59_RS15820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS15825	COG1879	ABC-type sugar transport system periplasmic component
BCV59_RS15830	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV59_RS15835	COG1129	ABC transporter
BCV59_RS15865	COG1522	sequence-specific DNA binding
BCV59_RS15870	COG0716	FMN binding
BCV59_RS15885	COG3312	ion transport
BCV59_RS15950	COG3188	usher protein
BCV59_RS15960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV59_RS15965	COG0573	inorganic phosphate transmembrane transporter activity
BCV59_RS15970	COG0581	inorganic phosphate transmembrane transporter activity
BCV59_RS15975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCV59_RS15980	COG0704	Plays a role in the regulation of phosphate uptake
BCV59_RS15985	COG3711	transcriptional antiterminator
BCV59_RS15990	COG1263	PTS System
BCV59_RS15990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS15990	COG2190	(PTS) system
BCV59_RS15995	COG2723	6-phospho-beta-galactosidase activity
BCV59_RS16015	COG2382	esterase
BCV59_RS16020	COG0363	glucosamine-6-phosphate deaminase activity
BCV59_RS16025	COG3196	Protein conserved in bacteria
BCV59_RS16035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV59_RS16040	COG2252	PERMEase
BCV59_RS16045	COG0431	NADPH-dependent FMN reductase
BCV59_RS16050	COG2091	lysine biosynthetic process via aminoadipic acid
BCV59_RS16065	COG0814	amino acid
BCV59_RS16110	COG0592	DNA-directed DNA polymerase activity
BCV59_RS16120	COG0187	DNA topoisomerase II activity
BCV59_RS16130	COG3753	Protein conserved in bacteria
BCV59_RS16135	COG0561	phosphatase activity
BCV59_RS16145	COG2186	Transcriptional regulator
BCV59_RS16150	COG3734	2-keto-3-deoxy-galactonokinase
BCV59_RS16155	COG0800	Aldolase
BCV59_RS16165	COG2271	Major facilitator Superfamily
BCV59_RS16175	COG0823	Involved in the tonB-independent uptake of proteins
BCV59_RS16180	COG5645	(Lipo)protein
BCV59_RS16200	COG2188	Transcriptional regulator
BCV59_RS16215	COG2207	Transcriptional regulator
BCV59_RS16220	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV59_RS16225	COG3119	arylsulfatase activity
BCV59_RS16235	COG2149	membrane
BCV59_RS16245	COG0641	radical SAM
BCV59_RS16250	COG2814	Major facilitator Superfamily
BCV59_RS16275	COG0028	Belongs to the TPP enzyme family
BCV59_RS16280	COG0440	acetolactate synthase activity
BCV59_RS16285	COG2197	response regulator
BCV59_RS16290	COG3851	Histidine kinase
BCV59_RS16295	COG2271	Major facilitator Superfamily
BCV59_RS16300	COG2271	Major facilitator Superfamily
BCV59_RS16310	COG2252	PERMEase
BCV59_RS16335	COG1464	Belongs to the NlpA lipoprotein family
BCV59_RS16340	COG0697	spore germination
BCV59_RS16345	COG2814	Major facilitator Superfamily
BCV59_RS16360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCV59_RS16375	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BCV59_RS16400	COG0582	viral genome integration into host DNA
BCV59_RS16410	COG2211	Major facilitator Superfamily
BCV59_RS16415	COG1501	Belongs to the glycosyl hydrolase 31 family
BCV59_RS16420	COG2982	Protein involved in outer membrane biogenesis
BCV59_RS16425	COG2233	PERMEase
BCV59_RS16430	COG0786	glutamate:sodium symporter activity
BCV59_RS16440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCV59_RS16445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV59_RS16450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV59_RS16460	COG0194	GDP metabolic process
BCV59_RS16470	COG2860	membrane
BCV59_RS16475	COG3645	SOS response
BCV59_RS16480	COG1561	YicC-like family, N-terminal region
BCV59_RS16505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCV59_RS16535	COG1519	Transferase
BCV59_RS16540	COG0859	PFAM glycosyl transferase family 9
BCV59_RS16545	COG0438	transferase activity, transferring glycosyl groups
BCV59_RS16550	COG0515	serine threonine protein kinase
BCV59_RS16560	COG3642	lipopolysaccharide core region biosynthetic process
BCV59_RS16580	COG0859	PFAM glycosyl transferase family 9
BCV59_RS16585	COG0859	PFAM glycosyl transferase family 9
BCV59_RS16600	COG0156	8-amino-7-oxononanoate synthase activity
BCV59_RS16610	COG1216	Glycosyl transferase, family 2
BCV59_RS16615	COG2861	carbohydrate metabolic process
BCV59_RS16620	COG4942	peptidase
BCV59_RS16630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV59_RS16635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCV59_RS16650	COG1045	serine acetyltransferase
BCV59_RS16655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCV59_RS16665	COG2186	Transcriptional regulator
BCV59_RS16670	COG1620	l-lactate permease
BCV59_RS16675	COG5295	Hep Hag repeat protein
BCV59_RS16695	COG3722	fumarate hydratase activity
BCV59_RS16705	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS16705	COG2213	PTS system mannitol-specific
BCV59_RS16715	COG1566	PFAM secretion protein HlyD family protein
BCV59_RS16725	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BCV59_RS16730	COG3209	COG3209 Rhs family protein
BCV59_RS16735	COG0625	glutathione transferase activity
BCV59_RS16745	COG3276	selenocysteine insertion sequence binding
BCV59_RS16750	COG1454	alcohol dehydrogenase
BCV59_RS16755	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS16770	COG1566	PFAM secretion protein HlyD family protein
BCV59_RS16775	COG0583	DNA-binding transcription factor activity
BCV59_RS16780	COG3713	MltA-interacting MipA family protein
BCV59_RS16785	COG0235	Class ii aldolase
BCV59_RS16790	COG3623	hexulose-6-phosphate isomerase
BCV59_RS16795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BCV59_RS16800	COG1070	Carbohydrate kinase
BCV59_RS16805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BCV59_RS16810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BCV59_RS16815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BCV59_RS16820	COG2731	YhcH YjgK YiaL family protein
BCV59_RS16830	COG1414	Transcriptional regulator
BCV59_RS16835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS16845	COG3977	Valine--pyruvate aminotransferase
BCV59_RS16850	COG0366	Alpha amylase catalytic
BCV59_RS16855	COG2992	FlgJ-related protein
BCV59_RS16860	COG1609	Transcriptional regulator
BCV59_RS16860	COG2207	Transcriptional regulator
BCV59_RS16865	COG4214	carbohydrate transport
BCV59_RS16875	COG4213	ABC transporter substrate-binding protein
BCV59_RS16890	COG4682	membrane
BCV59_RS16895	COG4682	membrane
BCV59_RS16900	COG3274	enterobacterial common antigen metabolic process
BCV59_RS16925	COG1278	Cold shock
BCV59_RS16930	COG2944	sequence-specific DNA binding
BCV59_RS16945	COG2885	chlorophyll binding
BCV59_RS16950	COG0243	molybdopterin cofactor binding
BCV59_RS16955	COG0456	acetyltransferase
BCV59_RS16960	COG2818	Glycosylase
BCV59_RS16965	COG5571	outer membrane autotransporter
BCV59_RS16970	COG2223	nitrite transmembrane transporter activity
BCV59_RS16975	COG2194	sulfuric ester hydrolase activity
BCV59_RS16990	COG0747	negative chemotaxis
BCV59_RS17000	COG0601	transmembrane transport
BCV59_RS17005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV59_RS17010	COG0444	Belongs to the ABC transporter superfamily
BCV59_RS17015	COG4608	Belongs to the ABC transporter superfamily
BCV59_RS17020	COG0814	amino acid
BCV59_RS17040	COG2194	sulfuric ester hydrolase activity
BCV59_RS17065	COG1215	transferase activity, transferring glycosyl groups
BCV59_RS17070	COG1215	transferase activity, transferring glycosyl groups
BCV59_RS17075	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BCV59_RS17080	COG0457	Tetratricopeptide repeat
BCV59_RS17080	COG3118	belongs to the thioredoxin family
BCV59_RS17085	COG2200	EAL domain
BCV59_RS17085	COG2199	diguanylate cyclase activity
BCV59_RS17095	COG0612	Peptidase, M16
BCV59_RS17100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS17110	COG2200	EAL domain
BCV59_RS17115	COG2982	Protein involved in outer membrane biogenesis
BCV59_RS17120	COG0477	Major facilitator Superfamily
BCV59_RS17125	COG1295	ribonuclease BN
BCV59_RS17130	COG0583	DNA-binding transcription factor activity
BCV59_RS17135	COG2197	response regulator
BCV59_RS17145	COG1858	cytochrome C peroxidase
BCV59_RS17150	COG0076	glutamate decarboxylase activity
BCV59_RS17160	COG2207	Transcriptional regulator
BCV59_RS17165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV59_RS17170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV59_RS17180	COG2771	luxR family
BCV59_RS17185	COG3247	response to pH
BCV59_RS17200	COG1285	pathogenesis
BCV59_RS17205	COG2197	response regulator
BCV59_RS17210	COG3065	identical protein binding
BCV59_RS17230	COG1393	Belongs to the ArsC family
BCV59_RS17235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCV59_RS17240	COG0640	Transcriptional regulator
BCV59_RS17255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV59_RS17260	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BCV59_RS17265	COG0339	signal peptide processing
BCV59_RS17275	COG3104	oligopeptide transport
BCV59_RS17280	COG0589	response to stress
BCV59_RS17290	COG0306	phosphate transporter
BCV59_RS17295	COG2081	HI0933 family
BCV59_RS17325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV59_RS17330	COG0842	Transport permease protein
BCV59_RS17330	COG1129	ABC transporter
BCV59_RS17335	COG0842	Transport permease protein
BCV59_RS17360	COG0444	Belongs to the ABC transporter superfamily
BCV59_RS17365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV59_RS17370	COG0601	transmembrane transport
BCV59_RS17375	COG0747	negative chemotaxis
BCV59_RS17380	COG2091	lysine biosynthetic process via aminoadipic acid
BCV59_RS17385	COG0628	permease
BCV59_RS17400	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BCV59_RS17415	COG3714	YhhN family
BCV59_RS17425	COG3776	membrane
BCV59_RS17430	COG0742	ribosomal rna small subunit methyltransferase
BCV59_RS17435	COG0552	protein localization to endoplasmic reticulum
BCV59_RS17440	COG2884	Cell division ATP-binding protein ftsE
BCV59_RS17445	COG2177	Part of the ABC transporter FtsEX involved in
BCV59_RS17450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV59_RS17455	COG0683	leucine binding
BCV59_RS17465	COG0456	acetyltransferase
BCV59_RS17470	COG0683	leucine binding
BCV59_RS17475	COG0559	Belongs to the binding-protein-dependent transport system permease family
BCV59_RS17480	COG4177	L-phenylalanine transmembrane transporter activity
BCV59_RS17485	COG0411	ABC transporter
BCV59_RS17490	COG0410	ABC transporter
BCV59_RS17500	COG1653	transport
BCV59_RS17505	COG1175	transmembrane transport
BCV59_RS17520	COG0584	glycerophosphoryl diester phosphodiesterase
BCV59_RS17530	COG0405	Gamma-glutamyltransferase
BCV59_RS17545	COG3157	Type VI secretion system effector, Hcp
BCV59_RS17550	COG1247	-acetyltransferase
BCV59_RS17555	COG0673	inositol 2-dehydrogenase activity
BCV59_RS17560	COG1741	Belongs to the pirin family
BCV59_RS17565	COG1609	Transcriptional regulator
BCV59_RS17570	COG3265	gluconokinase activity
BCV59_RS17575	COG2610	gluconate transmembrane transporter activity
BCV59_RS17580	COG2095	MarC family integral membrane protein
BCV59_RS17585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV59_RS17590	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCV59_RS17610	COG0058	SHG alpha-glucan phosphorylase activity
BCV59_RS17615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV59_RS17635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCV59_RS17650	COG1349	DNA-binding transcription factor activity
BCV59_RS17655	COG4650	regulator
BCV59_RS17660	COG1690	Belongs to the RtcB family
BCV59_RS17675	COG0058	SHG alpha-glucan phosphorylase activity
BCV59_RS17680	COG1640	4-alpha-glucanotransferase
BCV59_RS17685	COG2610	gluconate transmembrane transporter activity
BCV59_RS17695	COG1040	competence protein
BCV59_RS17705	COG5464	transposase or invertase
BCV59_RS17715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCV59_RS17720	COG1918	ferrous iron import across plasma membrane
BCV59_RS17725	COG2183	response to ionizing radiation
BCV59_RS17730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV59_RS17755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BCV59_RS17765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCV59_RS17770	COG1011	Hydrolase
BCV59_RS17780	COG0494	nUDIX hydrolase
BCV59_RS17785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCV59_RS17790	COG4972	Pilus assembly protein
BCV59_RS17795	COG3166	PFAM Fimbrial assembly family protein
BCV59_RS17810	COG4796	Type ii and iii secretion system protein
BCV59_RS17825	COG3266	domain, Protein
BCV59_RS17830	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BCV59_RS17835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCV59_RS17845	COG0180	Tryptophanyl-tRNA synthetase
BCV59_RS17850	COG2188	Transcriptional regulator
BCV59_RS17860	COG3457	Alanine racemase
BCV59_RS17870	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BCV59_RS17885	COG0626	cystathionine gamma-synthase activity
BCV59_RS17890	COG2188	Transcriptional regulator
BCV59_RS17900	COG1082	Xylose isomerase domain protein TIM barrel
BCV59_RS17905	COG2222	sugar isomerase
BCV59_RS17910	COG0531	amino acid
BCV59_RS17925	COG2116	formate transmembrane transporter activity
BCV59_RS17930	COG2146	nitrite reductase [NAD(P)H] activity
BCV59_RS17935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCV59_RS17945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCV59_RS17955	COG2184	nucleotidyltransferase activity
BCV59_RS17970	COG1289	transmembrane transporter activity
BCV59_RS17975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV59_RS17985	COG1765	OsmC-like protein
BCV59_RS17990	COG3954	Phosphoribulokinase
BCV59_RS18000	COG0429	hydrolase of the alpha beta-hydrolase fold
BCV59_RS18005	COG0488	(ABC) transporter
BCV59_RS18020	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BCV59_RS18025	COG1047	Peptidyl-prolyl cis-trans
BCV59_RS18035	COG0545	Peptidyl-prolyl cis-trans isomerase
BCV59_RS18040	COG2964	Protein conserved in bacteria
BCV59_RS18115	COG0089	rRNA binding
BCV59_RS18205	COG0201	protein transport
BCV59_RS18245	COG0789	Transcriptional regulator
BCV59_RS18250	COG3036	rescue of stalled ribosome
BCV59_RS18260	COG0569	domain protein
BCV59_RS18280	COG0758	DNA mediated transformation
BCV59_RS18290	COG0551	DNA topoisomerase type I activity
BCV59_RS18310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV59_RS18350	COG1126	abc transporter atp-binding protein
BCV59_RS18355	COG0765	amino acid transport
BCV59_RS18360	COG4597	amino acid ABC transporter
BCV59_RS18365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS18390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV59_RS18395	COG1309	transcriptional regulator
BCV59_RS18405	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BCV59_RS18415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV59_RS18425	COG4145	pantothenate transmembrane transporter activity
BCV59_RS18430	COG3924	membrane
BCV59_RS18435	COG0439	Biotin carboxylase
BCV59_RS18440	COG0511	ligase activity, forming carbon-carbon bonds
BCV59_RS18460	COG0604	alcohol dehydrogenase
BCV59_RS18465	COG2199	diguanylate cyclase activity
BCV59_RS18465	COG2200	EAL domain
BCV59_RS18475	COG1077	Cell shape determining protein MreB Mrl
BCV59_RS18480	COG1792	Involved in formation and maintenance of cell shape
BCV59_RS18485	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCV59_RS18495	COG1530	ribonuclease E activity
BCV59_RS18500	COG3164	Protein of unknown function
BCV59_RS18505	COG0312	modulator of DNA gyrase
BCV59_RS18510	COG0583	DNA-binding transcription factor activity
BCV59_RS18530	COG2732	(Barnase) inhibitor
BCV59_RS18550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV59_RS18555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV59_RS18560	COG3105	Protein conserved in bacteria
BCV59_RS18565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCV59_RS18580	COG0625	glutathione transferase activity
BCV59_RS18585	COG2969	positive regulation of protein catabolic process
BCV59_RS18590	COG3069	C4-dicarboxylate transmembrane transporter activity
BCV59_RS18620	COG2731	YhcH YjgK YiaL family protein
BCV59_RS18630	COG4804	nuclease activity
BCV59_RS18635	COG0493	'glutamate synthase
BCV59_RS18640	COG0067	glutamate synthase
BCV59_RS18640	COG0070	glutamate synthase
BCV59_RS18640	COG0069	glutamate synthase activity
BCV59_RS18645	COG1242	4 iron, 4 sulfur cluster binding
BCV59_RS18650	COG0784	Response regulator, receiver
BCV59_RS18650	COG2198	Histidine kinase
BCV59_RS18650	COG5002	protein histidine kinase activity
BCV59_RS18655	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BCV59_RS18665	COG0515	serine threonine protein kinase
BCV59_RS18670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS18685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCV59_RS18690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCV59_RS18695	COG1137	ATPase activity
BCV59_RS18700	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BCV59_RS18705	COG3117	lipopolysaccharide transmembrane transporter activity
BCV59_RS18710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BCV59_RS18715	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BCV59_RS18715	COG0517	IMP dehydrogenase activity
BCV59_RS18720	COG0530	calcium, potassium:sodium antiporter activity
BCV59_RS18725	COG1127	ABC transporter
BCV59_RS18730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV59_RS18735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV59_RS18740	COG2854	intermembrane phospholipid transfer
BCV59_RS18745	COG3113	response to antibiotic
BCV59_RS18750	COG5007	Belongs to the BolA IbaG family
BCV59_RS18760	COG3423	Transcriptional regulator
BCV59_RS18765	COG0142	geranyltranstransferase activity
BCV59_RS18780	COG0697	spore germination
BCV59_RS18790	COG2027	D-alanyl-D-alanine carboxypeptidase
BCV59_RS18795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV59_RS18800	COG1534	Rna-binding protein
BCV59_RS18810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV59_RS18815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCV59_RS18825	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCV59_RS18855	COG0195	Participates in both transcription termination and antitermination
BCV59_RS18890	COG0513	Belongs to the DEAD box helicase family
BCV59_RS18900	COG0814	amino acid
BCV59_RS18905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV59_RS18910	COG0826	peptidase U32
BCV59_RS18915	COG0826	peptidase U32
BCV59_RS18920	COG3154	lipid carrier protein
BCV59_RS18925	COG3153	acetyltransferase
BCV59_RS18940	COG0693	protein deglycase activity
BCV59_RS18945	COG0702	epimerase
BCV59_RS18950	COG0701	Predicted permease
BCV59_RS18955	COG2823	Periplasmic or secreted lipoprotein
BCV59_RS18970	COG3107	peptidoglycan biosynthetic process
BCV59_RS18975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCV59_RS18980	COG3539	Fimbrial protein
BCV59_RS18995	COG3539	Fimbrial protein
BCV59_RS19000	COG0363	glucosamine-6-phosphate deaminase activity
BCV59_RS19005	COG3716	PTS system mannose fructose sorbose family IID component
BCV59_RS19010	COG3715	PTS system
BCV59_RS19015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS19025	COG2222	sugar isomerase
BCV59_RS19030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV59_RS19035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS19040	COG3716	PTS system mannose fructose sorbose family IID component
BCV59_RS19050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS19060	COG1349	DNA-binding transcription factor activity
BCV59_RS19070	COG2002	toxin-antitoxin pair type II binding
BCV59_RS19075	COG2721	sulfolactate sulfo-lyase activity
BCV59_RS19080	COG2271	Major facilitator Superfamily
BCV59_RS19090	COG2084	Dehydrogenase
BCV59_RS19095	COG1929	Belongs to the glycerate kinase type-1 family
BCV59_RS19120	COG0583	DNA-binding transcription factor activity
BCV59_RS19125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCV59_RS19135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCV59_RS19140	COG1882	Formate acetyltransferase
BCV59_RS19145	COG0251	oxidation-reduction process
BCV59_RS19150	COG1760	l-serine dehydratase
BCV59_RS19155	COG0814	amino acid
BCV59_RS19170	COG1741	Belongs to the pirin family
BCV59_RS19175	COG0583	DNA-binding transcription factor activity
BCV59_RS19180	COG3152	Membrane
BCV59_RS19185	COG3152	Membrane
BCV59_RS19190	COG0435	Glutathione S-transferase
BCV59_RS19195	COG2259	Doxx family
BCV59_RS19205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BCV59_RS19210	COG4575	ribosome binding
BCV59_RS19215	COG1422	Protein of unknown function (DUF1090)
BCV59_RS19225	COG0586	Pfam SNARE associated Golgi protein
BCV59_RS19230	COG2186	Transcriptional regulator
BCV59_RS19255	COG2271	Major facilitator Superfamily
BCV59_RS19265	COG2721	sulfolactate sulfo-lyase activity
BCV59_RS19275	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BCV59_RS19280	COG0861	Integral membrane protein TerC family
BCV59_RS19285	COG0673	inositol 2-dehydrogenase activity
BCV59_RS19290	COG2949	membrane
BCV59_RS19295	COG1451	nucleotide metabolic process
BCV59_RS19310	COG4680	protein conserved in bacteria
BCV59_RS19315	COG5499	transcription regulator containing HTH domain
BCV59_RS19320	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCV59_RS19320	COG1902	pentaerythritol trinitrate reductase activity
BCV59_RS19325	COG3408	Glycogen debranching enzyme
BCV59_RS19325	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BCV59_RS19335	COG0531	amino acid
BCV59_RS19340	COG2731	YhcH YjgK YiaL family protein
BCV59_RS19345	COG3250	beta-galactosidase activity
BCV59_RS19350	COG1609	Transcriptional regulator
BCV59_RS19355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV59_RS19365	COG0840	transmembrane signaling receptor activity
BCV59_RS19370	COG1695	Transcriptional regulator
BCV59_RS19375	COG2375	cellular response to nickel ion
BCV59_RS19400	COG4983	Phage plasmid primase, P4 family domain protein
BCV59_RS19415	COG3188	usher protein
BCV59_RS19420	COG3121	Chaperone
BCV59_RS19425	COG3539	Fimbrial protein
BCV59_RS19435	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCV59_RS19440	COG2268	Band 7 protein
BCV59_RS19465	COG3025	triphosphatase activity
BCV59_RS19475	COG4991	sh3 domain protein
BCV59_RS19490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV59_RS19500	COG0583	DNA-binding transcription factor activity
BCV59_RS19505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV59_RS19510	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV59_RS19515	COG0471	metal ion transport
BCV59_RS19525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCV59_RS19530	COG0358	DNA primase activity
BCV59_RS19535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV59_RS19580	COG2003	Belongs to the UPF0758 family
BCV59_RS19705	COG1358	cellular component organization or biogenesis
BCV59_RS19735	COG4372	Transposase
BCV59_RS19760	COG0254	rRNA binding
BCV59_RS19780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV59_RS19785	COG2194	sulfuric ester hydrolase activity
BCV59_RS19840	COG4372	Transposase
BCV59_RS19860	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS19875	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS19880	COG4372	Transposase
BCV59_RS19905	COG3188	usher protein
BCV59_RS19910	COG3539	Fimbrial protein
BCV59_RS19915	COG2960	long-chain fatty acid transporting porin activity
BCV59_RS19935	COG3384	dioxygenase
BCV59_RS19940	COG0754	glutathionylspermidine amidase activity
BCV59_RS19955	COG1538	Outer membrane efflux protein
BCV59_RS19960	COG0494	nUDIX hydrolase
BCV59_RS19965	COG3151	Protein conserved in bacteria
BCV59_RS19970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BCV59_RS19975	COG3150	esterase
BCV59_RS19980	COG0187	DNA topoisomerase II activity
BCV59_RS19985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BCV59_RS19990	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCV59_RS19995	COG0642	Histidine kinase
BCV59_RS20000	COG0745	RESPONSE REGULATOR receiver
BCV59_RS20005	COG3111	PFAM Bacterial OB fold (BOF) protein
BCV59_RS20010	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BCV59_RS20020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCV59_RS20025	COG0204	Acyl-transferase
BCV59_RS20030	COG2132	Multicopper oxidase
BCV59_RS20035	COG1032	radical SAM domain protein
BCV59_RS20050	COG0656	L-ascorbic acid biosynthetic process
BCV59_RS20055	COG1979	alcohol dehydrogenase
BCV59_RS20065	COG2207	Transcriptional regulator
BCV59_RS20070	COG0586	Pfam SNARE associated Golgi protein
BCV59_RS20075	COG0626	cystathionine gamma-synthase activity
BCV59_RS20085	COG0811	peptide transport
BCV59_RS20090	COG0848	biopolymer transport protein
BCV59_RS20095	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS20105	COG0667	Aldo Keto reductase
BCV59_RS20125	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BCV59_RS20130	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS20135	COG5557	Pfam Polysulphide reductase, NrfD
BCV59_RS20140	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BCV59_RS20145	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCV59_RS20150	COG1773	rubredoxin
BCV59_RS20160	COG0298	carbon dioxide binding
BCV59_RS20165	COG0625	glutathione transferase activity
BCV59_RS20170	COG0754	glutathionylspermidine amidase activity
BCV59_RS20175	COG0306	phosphate transporter
BCV59_RS20180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BCV59_RS20185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BCV59_RS20190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BCV59_RS20195	COG2244	polysaccharide biosynthetic process
BCV59_RS20205	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BCV59_RS20210	COG0795	lipopolysaccharide-transporting ATPase activity
BCV59_RS20220	COG0156	8-amino-7-oxononanoate synthase activity
BCV59_RS20225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCV59_RS20235	COG0318	PFAM AMP-dependent synthetase and ligase
BCV59_RS20240	COG0456	acetyltransferase
BCV59_RS20245	COG2186	Transcriptional regulator
BCV59_RS20250	COG0277	FAD linked oxidase domain protein
BCV59_RS20255	COG0277	FAD linked oxidase domain protein
BCV59_RS20260	COG0247	lactate metabolic process
BCV59_RS20265	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BCV59_RS20275	COG1620	l-lactate permease
BCV59_RS20285	COG3064	Membrane
BCV59_RS20310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV59_RS20315	COG1459	type II secretion system
BCV59_RS20320	COG2165	general secretion pathway protein
BCV59_RS20350	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BCV59_RS20385	COG2003	Belongs to the UPF0758 family
BCV59_RS20465	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS20470	COG4372	Transposase
BCV59_RS20555	COG3596	GTP binding
BCV59_RS20585	COG2433	Pfam Transposase IS66
BCV59_RS20590	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS20600	COG4372	Transposase
BCV59_RS20605	COG0582	viral genome integration into host DNA
BCV59_RS20615	COG1811	Na channel or pump
BCV59_RS20620	COG1982	Orn Lys Arg decarboxylase major
BCV59_RS20625	COG2211	Major facilitator Superfamily
BCV59_RS20640	COG1194	a g-specific adenine glycosylase
BCV59_RS20650	COG3171	Protein conserved in bacteria
BCV59_RS20665	COG0252	asparaginase activity
BCV59_RS20680	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BCV59_RS20685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BCV59_RS20690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV59_RS20705	COG0762	integral membrane protein
BCV59_RS20710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCV59_RS20715	COG2805	Type II/IV secretion system protein
BCV59_RS20730	COG0189	ligase activity
BCV59_RS20735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCV59_RS20740	COG2356	endonuclease I
BCV59_RS20750	COG2814	Major facilitator Superfamily
BCV59_RS20775	COG1166	arginine decarboxylase activity
BCV59_RS20785	COG0501	Belongs to the peptidase M48B family
BCV59_RS20790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV59_RS20795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS20800	COG2213	PTS system mannitol-specific
BCV59_RS20805	COG1063	alcohol dehydrogenase
BCV59_RS20810	COG1494	fructose-1,6-bisphosphatase
BCV59_RS20815	COG3722	fumarate hydratase activity
BCV59_RS20820	COG1072	(Pantothenic acid kinase))
BCV59_RS20825	COG1122	ATPase activity
BCV59_RS20830	COG1122	ATPase activity
BCV59_RS20860	COG0191	fructose-bisphosphate aldolase activity
BCV59_RS20865	COG0668	transmembrane transport
BCV59_RS20875	COG2968	Membrane
BCV59_RS20880	COG0583	DNA-binding transcription factor activity
BCV59_RS20885	COG0427	acetyl-CoA hydrolase
BCV59_RS20890	COG1024	Enoyl-CoA hydratase
BCV59_RS20895	COG1703	isobutyryl-CoA mutase activity
BCV59_RS20900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCV59_RS20900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCV59_RS20915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV59_RS20925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCV59_RS20945	COG0006	proline dipeptidase activity
BCV59_RS20950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV59_RS20955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV59_RS20975	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS20980	COG2723	6-phospho-beta-galactosidase activity
BCV59_RS20990	COG1272	protein, Hemolysin III
BCV59_RS21000	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BCV59_RS21010	COG0716	FMN binding
BCV59_RS21015	COG4974	Belongs to the 'phage' integrase family
BCV59_RS21020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV59_RS21025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCV59_RS21060	COG2233	PERMEase
BCV59_RS21070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS21070	COG0493	'glutamate synthase
BCV59_RS21075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS21080	COG2252	PERMEase
BCV59_RS21085	COG0402	S-adenosylhomocysteine deaminase activity
BCV59_RS21090	COG2233	PERMEase
BCV59_RS21100	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BCV59_RS21105	COG0402	S-adenosylhomocysteine deaminase activity
BCV59_RS21110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS21110	COG0493	'glutamate synthase
BCV59_RS21115	COG2068	MobA-Related Protein
BCV59_RS21120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCV59_RS21125	COG3608	succinylglutamate desuccinylase aspartoacylase
BCV59_RS21125	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BCV59_RS21130	COG0549	Belongs to the carbamate kinase family
BCV59_RS21140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV59_RS21145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCV59_RS21150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCV59_RS21155	COG3829	transcription factor binding
BCV59_RS21160	COG2080	2 iron, 2 sulfur cluster binding
BCV59_RS21165	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BCV59_RS21170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BCV59_RS21180	COG4942	peptidase
BCV59_RS21275	COG2197	response regulator
BCV59_RS21290	COG0457	Tetratricopeptide repeat
BCV59_RS21290	COG3710	Transcriptional regulator
BCV59_RS21295	COG0457	Tetratricopeptide repeat
BCV59_RS21325	COG3710	Transcriptional regulator
BCV59_RS21335	COG0814	amino acid
BCV59_RS21340	COG0183	Belongs to the thiolase family
BCV59_RS21350	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS21355	COG2814	Major facilitator Superfamily
BCV59_RS21360	COG1794	racemase activity, acting on amino acids and derivatives
BCV59_RS21365	COG0583	DNA-binding transcription factor activity
BCV59_RS21375	COG1609	Transcriptional regulator
BCV59_RS21390	COG0667	Aldo Keto reductase
BCV59_RS21400	COG0861	Integral membrane protein TerC family
BCV59_RS21425	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BCV59_RS21440	COG2165	general secretion pathway protein
BCV59_RS21445	COG4795	General secretion pathway protein
BCV59_RS21455	COG4967	type IV pilus modification protein PilV
BCV59_RS21460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BCV59_RS21475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV59_RS21480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BCV59_RS21480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCV59_RS21485	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV59_RS21505	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BCV59_RS21510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCV59_RS21515	COG2166	iron-sulfur cluster assembly
BCV59_RS21520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCV59_RS21530	COG0583	DNA-binding transcription factor activity
BCV59_RS21535	COG2363	Small membrane protein
BCV59_RS21545	COG1349	DNA-binding transcription factor activity
BCV59_RS21555	COG1070	Carbohydrate kinase
BCV59_RS21565	COG0738	Major facilitator superfamily
BCV59_RS21570	COG0235	Class ii aldolase
BCV59_RS21575	COG1454	alcohol dehydrogenase
BCV59_RS21585	COG1760	l-serine dehydratase
BCV59_RS21590	COG0814	amino acid
BCV59_RS21595	COG1611	Belongs to the LOG family
BCV59_RS21615	COG3098	single-species biofilm formation
BCV59_RS21620	COG0564	pseudouridine synthase activity
BCV59_RS21625	COG0716	FMN binding
BCV59_RS21630	COG2271	Major facilitator Superfamily
BCV59_RS21635	COG4948	Mandelate Racemase Muconate Lactonizing
BCV59_RS21640	COG4948	Mandelate Racemase Muconate Lactonizing
BCV59_RS21645	COG4999	Histidine kinase
BCV59_RS21645	COG3437	response regulator, receiver
BCV59_RS21645	COG3850	Histidine kinase
BCV59_RS21645	COG2205	protein histidine kinase activity
BCV59_RS21655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV59_RS21660	COG2336	PFAM SpoVT AbrB
BCV59_RS21665	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCV59_RS21670	COG3956	TIGRFAM MazG family protein
BCV59_RS21685	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BCV59_RS21695	COG0602	queuosine metabolic process
BCV59_RS21700	COG1070	Carbohydrate kinase
BCV59_RS21705	COG2223	nitrite transmembrane transporter activity
BCV59_RS21710	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS21715	COG0277	FAD linked oxidase domain protein
BCV59_RS21720	COG0477	Major facilitator Superfamily
BCV59_RS21725	COG2086	electron transfer activity
BCV59_RS21730	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCV59_RS21735	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCV59_RS21740	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BCV59_RS21745	COG0644	oxidoreductase
BCV59_RS21750	COG0720	synthase
BCV59_RS21775	COG1203	CRISPR-associated helicase, Cas3
BCV59_RS21790	COG1857	crispr-associated protein
BCV59_RS21805	COG1518	maintenance of DNA repeat elements
BCV59_RS21810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS21815	COG2234	aminopeptidase activity
BCV59_RS21870	COG4942	peptidase
BCV59_RS21870	COG1388	LysM domain
BCV59_RS21875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV59_RS21890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BCV59_RS21900	COG2610	gluconate transmembrane transporter activity
BCV59_RS21905	COG3622	Belongs to the hyi family
BCV59_RS21910	COG0235	Class ii aldolase
BCV59_RS21915	COG3395	kinase activity
BCV59_RS21920	COG2084	Dehydrogenase
BCV59_RS21925	COG1349	DNA-binding transcription factor activity
BCV59_RS21930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV59_RS21950	COG3604	Transcriptional regulator
BCV59_RS21955	COG0309	Hydrogenase expression formation protein (HypE)
BCV59_RS21960	COG0409	Hydrogenase expression formation protein
BCV59_RS21965	COG0298	carbon dioxide binding
BCV59_RS21970	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BCV59_RS21975	COG0375	protein maturation
BCV59_RS21990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS21995	COG0651	ATP synthesis coupled electron transport
BCV59_RS22000	COG0650	Formate hydrogenlyase subunit 4
BCV59_RS22005	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BCV59_RS22005	COG3261	NADH dehydrogenase
BCV59_RS22010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV59_RS22015	COG3260	NADH ubiquinone oxidoreductase 20
BCV59_RS22025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCV59_RS22035	COG4680	protein conserved in bacteria
BCV59_RS22040	COG5499	transcription regulator containing HTH domain
BCV59_RS22045	COG2723	6-phospho-beta-galactosidase activity
BCV59_RS22055	COG1609	Transcriptional regulator
BCV59_RS22060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS22065	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BCV59_RS22090	COG1349	DNA-binding transcription factor activity
BCV59_RS22095	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS22100	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS22110	COG3732	PTS system glucitol sorbitol-specific
BCV59_RS22115	COG3730	PTS system glucitol sorbitol-specific
BCV59_RS22120	COG2951	lytic endotransglycosylase activity
BCV59_RS22125	COG1546	Belongs to the CinA family
BCV59_RS22145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCV59_RS22150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCV59_RS22180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV59_RS22185	COG1238	metal cluster binding
BCV59_RS22200	COG2814	Major facilitator Superfamily
BCV59_RS22205	COG1566	PFAM secretion protein HlyD family protein
BCV59_RS22210	COG1846	Transcriptional regulator
BCV59_RS22220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BCV59_RS22230	COG2113	Glycine betaine
BCV59_RS22235	COG4176	ABC-type proline glycine betaine transport system permease component
BCV59_RS22240	COG4175	Glycine betaine
BCV59_RS22245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV59_RS22250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV59_RS22260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCV59_RS22265	COG4575	ribosome binding
BCV59_RS22280	COG2916	Histone family protein nucleoid-structuring protein H-NS
BCV59_RS22285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV59_RS22290	COG0640	Transcriptional regulator
BCV59_RS22295	COG0401	homolog of Blt101
BCV59_RS22300	COG1652	LysM domain
BCV59_RS22305	COG1802	Transcriptional regulator
BCV59_RS22310	COG1113	amino acid transport
BCV59_RS22315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCV59_RS22320	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS22325	COG0579	oxidoreductase
BCV59_RS22335	COG0366	Alpha amylase catalytic
BCV59_RS22450	COG2867	negative regulation of translational initiation
BCV59_RS22460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV59_RS22465	COG0497	DNA recombination
BCV59_RS22485	COG4536	flavin adenine dinucleotide binding
BCV59_RS22490	COG4137	Cytochrome C assembly protein
BCV59_RS22495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCV59_RS22520	COG2885	chlorophyll binding
BCV59_RS22525	COG2199	diguanylate cyclase activity
BCV59_RS22540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV59_RS22545	COG1605	Chorismate mutase
BCV59_RS22545	COG0287	Prephenate dehydrogenase
BCV59_RS22550	COG0077	Prephenate dehydratase
BCV59_RS22550	COG1605	Chorismate mutase
BCV59_RS22555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCV59_RS22565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV59_RS22570	COG0564	pseudouridine synthase activity
BCV59_RS22575	COG1496	oxidoreductase activity
BCV59_RS22580	COG0542	response to heat
BCV59_RS22605	COG0477	Major facilitator Superfamily
BCV59_RS22610	COG5544	Lipoprotein
BCV59_RS22615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV59_RS22620	COG1042	CoA-binding domain protein
BCV59_RS22620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV59_RS22620	COG0045	succinate-CoA ligase (ADP-forming) activity
BCV59_RS22625	COG3148	PFAM DTW domain containing protein
BCV59_RS22630	COG3118	belongs to the thioredoxin family
BCV59_RS22640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV59_RS22660	COG0583	DNA-binding transcription factor activity
BCV59_RS22670	COG0513	Belongs to the DEAD box helicase family
BCV59_RS22680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCV59_RS22690	COG1595	DNA-templated transcription, initiation
BCV59_RS22695	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BCV59_RS22700	COG3026	antisigma factor binding
BCV59_RS22705	COG3086	response to oxidative stress
BCV59_RS22715	COG0681	Belongs to the peptidase S26 family
BCV59_RS22760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS22765	COG1737	Transcriptional regulator
BCV59_RS22770	COG0560	Phosphoserine phosphatase
BCV59_RS22790	COG2205	protein histidine kinase activity
BCV59_RS22795	COG3170	Tfp pilus assembly protein FimV
BCV59_RS22800	COG2204	response regulator
BCV59_RS22805	COG0347	Belongs to the P(II) protein family
BCV59_RS22810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV59_RS22810	COG1017	nitric oxide dioxygenase activity
BCV59_RS22820	COG1940	carbohydrate kinase activity
BCV59_RS22825	COG0457	Tetratricopeptide repeat
BCV59_RS22830	COG1879	ABC-type sugar transport system periplasmic component
BCV59_RS22835	COG1129	ABC transporter
BCV59_RS22840	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV59_RS22845	COG1063	alcohol dehydrogenase
BCV59_RS22850	COG2017	converts alpha-aldose to the beta-anomer
BCV59_RS22855	COG2259	Doxx family
BCV59_RS22880	COG4638	Rieske (2fe-2S)
BCV59_RS22885	COG0583	DNA-binding transcription factor activity
BCV59_RS22890	COG2814	Major facilitator Superfamily
BCV59_RS22895	COG3711	transcriptional antiterminator
BCV59_RS22900	COG1073	alpha beta
BCV59_RS22905	COG0483	inositol monophosphate 1-phosphatase activity
BCV59_RS22925	COG0822	iron-sulfur transferase activity
BCV59_RS22945	COG0633	Ferredoxin
BCV59_RS22950	COG2975	iron-sulfur cluster assembly
BCV59_RS22965	COG2897	thiosulfate sulfurtransferase activity
BCV59_RS22970	COG2373	Large extracellular alpha-helical protein
BCV59_RS22975	COG4953	penicillin-binding protein 1C
BCV59_RS23005	COG2976	Protein conserved in bacteria
BCV59_RS23020	COG1645	bacterial-type flagellum-dependent swarming motility
BCV59_RS23030	COG0517	IMP dehydrogenase activity
BCV59_RS23030	COG0516	GMP reductase activity
BCV59_RS23045	COG3133	Outer membrane lipoprotein
BCV59_RS23060	COG2200	EAL domain
BCV59_RS23065	COG0248	Ppx GppA phosphatase
BCV59_RS23070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCV59_RS23075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCV59_RS23090	COG2233	PERMEase
BCV59_RS23100	COG1393	Belongs to the ArsC family
BCV59_RS23105	COG4783	chaperone-mediated protein folding
BCV59_RS23110	COG0628	permease
BCV59_RS23115	COG2116	formate transmembrane transporter activity
BCV59_RS23130	COG3260	NADH ubiquinone oxidoreductase 20
BCV59_RS23135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV59_RS23140	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BCV59_RS23140	COG3261	NADH dehydrogenase
BCV59_RS23145	COG0651	ATP synthesis coupled electron transport
BCV59_RS23150	COG4237	Hydrogenase 4 membrane
BCV59_RS23155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCV59_RS23165	COG0651	ATP synthesis coupled electron transport
BCV59_RS23170	COG0651	ATP synthesis coupled electron transport
BCV59_RS23175	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS23180	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCV59_RS23185	COG2716	regulation of RNA biosynthetic process
BCV59_RS23195	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BCV59_RS23220	COG2321	neutral zinc metallopeptidase
BCV59_RS23230	COG0400	carboxylic ester hydrolase activity
BCV59_RS23245	COG1393	Belongs to the ArsC family
BCV59_RS23255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV59_RS23260	COG3850	Histidine kinase
BCV59_RS23265	COG0493	'glutamate synthase
BCV59_RS23265	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS23275	COG5342	invasion associated locus B
BCV59_RS23280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV59_RS23285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV59_RS23290	COG0281	malic enzyme
BCV59_RS23290	COG0280	phosphate acetyltransferase
BCV59_RS23295	COG4810	utilization protein
BCV59_RS23300	COG4917	ethanolamine utilization protein
BCV59_RS23305	COG4766	ethanolamine catabolic process
BCV59_RS23310	COG4812	Cobalamin adenosyltransferase
BCV59_RS23320	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BCV59_RS23325	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BCV59_RS23330	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS23335	COG4820	ethanolamine utilization protein (EutJ)
BCV59_RS23340	COG1454	alcohol dehydrogenase
BCV59_RS23345	COG3192	ethanolamine utilization protein
BCV59_RS23350	COG4819	ethanolamine utilization protein
BCV59_RS23355	COG4303	Ethanolamine ammonia lyase large subunit
BCV59_RS23365	COG4816	utilization protein
BCV59_RS23370	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BCV59_RS23375	COG2207	Transcriptional regulator
BCV59_RS23385	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV59_RS23405	COG2837	iron assimilation
BCV59_RS23410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV59_RS23415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV59_RS23415	COG1263	PTS System
BCV59_RS23430	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS23435	COG4150	thiosulfate binding
BCV59_RS23440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCV59_RS23445	COG4208	sulfate ABC transporter
BCV59_RS23450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCV59_RS23455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV59_RS23470	COG2190	(PTS) system
BCV59_RS23475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV59_RS23480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS23485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV59_RS23505	COG3530	Putative quorum-sensing-regulated virulence factor
BCV59_RS23510	COG0385	Bile acid
BCV59_RS23515	COG0583	DNA-binding transcription factor activity
BCV59_RS23550	COG3415	Transposase
BCV59_RS23555	COG3415	Transposase
BCV59_RS23570	COG2200	EAL domain
BCV59_RS23570	COG2199	diguanylate cyclase activity
BCV59_RS23575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV59_RS23605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS23610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS23615	COG0006	proline dipeptidase activity
BCV59_RS23620	COG1363	Peptidase, m42
BCV59_RS23630	COG2207	Transcriptional regulator
BCV59_RS23635	COG3279	Response regulator of the LytR AlgR family
BCV59_RS23640	COG3275	phosphorelay sensor kinase activity
BCV59_RS23645	COG0436	Aminotransferase
BCV59_RS23650	COG1560	Kdo2-lipid A biosynthetic process
BCV59_RS23680	COG0028	Belongs to the TPP enzyme family
BCV59_RS23685	COG0679	Auxin Efflux Carrier
BCV59_RS23690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BCV59_RS23695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS23695	COG0784	Response regulator, receiver
BCV59_RS23695	COG2198	Histidine kinase
BCV59_RS23695	COG2205	protein histidine kinase activity
BCV59_RS23700	COG2197	response regulator
BCV59_RS23705	COG1566	PFAM secretion protein HlyD family protein
BCV59_RS23710	COG0477	Major facilitator Superfamily
BCV59_RS23720	COG2610	gluconate transmembrane transporter activity
BCV59_RS23935	COG0582	viral genome integration into host DNA
BCV59_RS23945	COG2116	formate transmembrane transporter activity
BCV59_RS23950	COG2853	Lipoprotein
BCV59_RS23960	COG2067	long-chain fatty acid transport protein
BCV59_RS23965	COG3691	Protein conserved in bacteria
BCV59_RS23980	COG2062	phosphohistidine phosphatase, SixA
BCV59_RS23985	COG3539	Fimbrial protein
BCV59_RS23990	COG3188	usher protein
BCV59_RS23995	COG3121	Chaperone
BCV59_RS24000	COG3539	Fimbrial protein
BCV59_RS24005	COG3539	Fimbrial protein
BCV59_RS24010	COG3539	Fimbrial protein
BCV59_RS24040	COG0730	response to heat
BCV59_RS24045	COG3101	peptidyl-lysine hydroxylation
BCV59_RS24060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV59_RS24065	COG2814	Major facilitator Superfamily
BCV59_RS24135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCV59_RS24220	COG4695	Portal protein
BCV59_RS24235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCV59_RS24335	COG4974	Belongs to the 'phage' integrase family
BCV59_RS24345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV59_RS24355	COG0586	Pfam SNARE associated Golgi protein
BCV59_RS24365	COG0285	dihydrofolate synthase activity
BCV59_RS24370	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BCV59_RS24375	COG1286	toxin biosynthetic process
BCV59_RS24380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCV59_RS24385	COG0163	prenyltransferase activity
BCV59_RS24395	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS24430	COG4372	Transposase
BCV59_RS24435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS24440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV59_RS24445	COG4215	(ABC) transporter
BCV59_RS24450	COG4160	amino acid transport
BCV59_RS24455	COG4598	ABC transporter
BCV59_RS24460	COG5464	transposase or invertase
BCV59_RS24465	COG1090	epimerase
BCV59_RS24470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV59_RS24475	COG0625	glutathione transferase activity
BCV59_RS24480	COG0625	glutathione transferase activity
BCV59_RS24485	COG0622	Phosphoesterase
BCV59_RS24490	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BCV59_RS24495	COG1288	antiporter activity
BCV59_RS24500	COG0280	phosphate acetyltransferase
BCV59_RS24500	COG0857	belongs to the CobB CobQ family
BCV59_RS24505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCV59_RS24525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV59_RS24530	COG0490	domain, Protein
BCV59_RS24530	COG0471	metal ion transport
BCV59_RS24540	COG0436	Aminotransferase
BCV59_RS24545	COG0583	DNA-binding transcription factor activity
BCV59_RS24565	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BCV59_RS24570	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BCV59_RS24575	COG1034	ATP synthesis coupled electron transport
BCV59_RS24590	COG0839	Belongs to the complex I subunit 6 family
BCV59_RS24600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCV59_RS24605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV59_RS24620	COG2234	aminopeptidase activity
BCV59_RS24635	COG2153	protein acetylation
BCV59_RS24640	COG4575	ribosome binding
BCV59_RS24645	COG1169	isochorismate synthase
BCV59_RS24660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCV59_RS24670	COG0318	PFAM AMP-dependent synthetase and ligase
BCV59_RS24735	COG1414	Transcriptional regulator
BCV59_RS24745	COG2271	Major facilitator Superfamily
BCV59_RS24755	COG5464	transposase or invertase
BCV59_RS24760	COG0247	lactate metabolic process
BCV59_RS24770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCV59_RS24775	COG2271	Major facilitator Superfamily
BCV59_RS24780	COG0584	glycerophosphoryl diester phosphodiesterase
BCV59_RS24785	COG0583	DNA-binding transcription factor activity
BCV59_RS24790	COG3642	lipopolysaccharide core region biosynthetic process
BCV59_RS24795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV59_RS24800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV59_RS24805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV59_RS24815	COG3468	outer membrane autotransporter barrel domain protein
BCV59_RS24825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCV59_RS24830	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
BCV59_RS24835	COG3234	Protein of unknown function (DUF1175)
BCV59_RS24840	COG2373	Large extracellular alpha-helical protein
BCV59_RS24845	COG5445	Predicted secreted protein (DUF2300)
BCV59_RS24850	COG4676	Protein conserved in bacteria
BCV59_RS24855	COG2205	protein histidine kinase activity
BCV59_RS24855	COG0784	Response regulator, receiver
BCV59_RS24860	COG2197	response regulator
BCV59_RS24865	COG0642	Histidine kinase
BCV59_RS24865	COG2198	Histidine kinase
BCV59_RS24880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV59_RS24885	COG1477	protein flavinylation
BCV59_RS24890	COG2169	Transcriptional regulator
BCV59_RS24890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV59_RS24895	COG3145	DNA-N1-methyladenine dioxygenase activity
BCV59_RS24900	COG4615	Cyclic peptide transporter
BCV59_RS24920	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS24920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV59_RS24925	COG3062	negative regulation of establishment of protein localization
BCV59_RS24935	COG0437	4 iron, 4 sulfur cluster binding
BCV59_RS24940	COG0348	domain, Protein
BCV59_RS24945	COG3043	anaerobic respiration
BCV59_RS24950	COG3005	denitrification pathway
BCV59_RS24955	COG4133	protoheme IX ABC transporter activity
BCV59_RS24960	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCV59_RS24965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCV59_RS24970	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCV59_RS24980	COG1138	Cytochrome C-type biogenesis protein
BCV59_RS24985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV59_RS24990	COG3088	subunit of a heme lyase
BCV59_RS24990	COG4235	cytochrome complex assembly
BCV59_RS24995	COG2197	response regulator
BCV59_RS25005	COG3468	outer membrane autotransporter barrel domain protein
BCV59_RS25015	COG3083	sulfuric ester hydrolase activity
BCV59_RS25035	COG1061	Type III restriction enzyme res subunit
BCV59_RS25040	COG1187	pseudouridine synthase activity
BCV59_RS25045	COG2814	Major facilitator Superfamily
BCV59_RS25055	COG4172	Belongs to the ABC transporter superfamily
BCV59_RS25060	COG4239	(ABC) transporter, permease
BCV59_RS25065	COG4174	ABC transporter (Permease)
BCV59_RS25070	COG4166	transmembrane transport
BCV59_RS25075	COG2200	EAL domain
BCV59_RS25080	COG0791	NLP P60 protein
BCV59_RS25090	COG0523	cobalamin synthesis protein
BCV59_RS25095	COG0246	Mannitol dehydrogenase
BCV59_RS25110	COG2814	Major facilitator Superfamily
BCV59_RS25115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS25115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS25120	COG1105	Belongs to the carbohydrate kinase PfkB family
BCV59_RS25125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS25125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV59_RS25125	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BCV59_RS25130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS25135	COG2313	pseudouridylate synthase activity
BCV59_RS25140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV59_RS25145	COG1522	sequence-specific DNA binding
BCV59_RS25145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS25155	COG2855	membrane
BCV59_RS25160	COG0583	DNA-binding transcription factor activity
BCV59_RS25165	COG0833	amino acid
BCV59_RS25170	COG4771	TonB-dependent receptor
BCV59_RS25190	COG2311	Membrane
BCV59_RS25200	COG1609	Transcriptional regulator
BCV59_RS25205	COG1879	ABC-type sugar transport system periplasmic component
BCV59_RS25210	COG1129	ABC transporter
BCV59_RS25215	COG4211	Belongs to the binding-protein-dependent transport system permease family
BCV59_RS25225	COG0493	'glutamate synthase
BCV59_RS25235	COG2949	membrane
BCV59_RS25245	COG1346	cytolysis
BCV59_RS25255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV59_RS25270	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS25285	COG1028	Short-chain dehydrogenase reductase Sdr
BCV59_RS25290	COG0586	Pfam SNARE associated Golgi protein
BCV59_RS25300	COG1686	Belongs to the peptidase S11 family
BCV59_RS25305	COG4372	Transposase
BCV59_RS25310	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS25330	COG0277	FAD linked oxidase domain protein
BCV59_RS25335	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV59_RS25340	COG1732	Glycine betaine
BCV59_RS25345	COG1174	glycine betaine transport
BCV59_RS25350	COG1125	glycine betaine transport
BCV59_RS25355	COG1174	glycine betaine transport
BCV59_RS25365	COG0789	Transcriptional regulator
BCV59_RS25370	COG3275	phosphorelay sensor kinase activity
BCV59_RS25375	COG3279	Response regulator of the LytR AlgR family
BCV59_RS25380	COG4807	Protein conserved in bacteria
BCV59_RS25385	COG4808	Protein conserved in bacteria
BCV59_RS25395	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BCV59_RS25400	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BCV59_RS25405	COG0714	Associated with various cellular activities
BCV59_RS25415	COG3831	ATPase activity
BCV59_RS25420	COG3831	ATPase activity
BCV59_RS25430	COG0489	protein tyrosine kinase activity
BCV59_RS25445	COG3539	Fimbrial protein
BCV59_RS25450	COG3121	Chaperone
BCV59_RS25455	COG3188	usher protein
BCV59_RS25460	COG3539	Fimbrial protein
BCV59_RS25465	COG5455	response to cobalt ion
BCV59_RS25470	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BCV59_RS25485	COG0351	phosphomethylpyrimidine kinase
BCV59_RS25490	COG3757	hydrolase, family 25
BCV59_RS25495	COG2188	Transcriptional regulator
BCV59_RS25500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV59_RS25505	COG1397	ADP-ribosylglycohydrolase
BCV59_RS25515	COG1830	Aldolase
BCV59_RS25530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS25535	COG3414	Phosphotransferase system galactitol-specific IIB component
BCV59_RS25540	COG3775	system Galactitol-specific IIC component
BCV59_RS25545	COG1063	alcohol dehydrogenase
BCV59_RS25570	COG0826	peptidase U32
BCV59_RS25580	COG3609	addiction module antidote protein, CC2985 family
BCV59_RS25590	COG0745	RESPONSE REGULATOR receiver
BCV59_RS25595	COG2205	protein histidine kinase activity
BCV59_RS25620	COG0582	viral genome integration into host DNA
BCV59_RS25685	COG3772	lysozyme
BCV59_RS25705	COG4220	transposase activity
BCV59_RS25760	COG4245	von Willebrand factor, type A
BCV59_RS25765	COG0631	protein serine/threonine phosphatase activity
BCV59_RS25770	COG3779	Protein conserved in bacteria
BCV59_RS25775	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
BCV59_RS25780	COG0443	Heat shock 70 kDa protein
BCV59_RS25785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCV59_RS25795	COG0572	uridine kinase
BCV59_RS25805	COG2982	Protein involved in outer membrane biogenesis
BCV59_RS25810	COG1253	flavin adenine dinucleotide binding
BCV59_RS25815	COG1596	polysaccharide export
BCV59_RS25820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCV59_RS25825	COG0489	protein tyrosine kinase activity
BCV59_RS25825	COG3206	protein involved in exopolysaccharide biosynthesis
BCV59_RS25830	COG0463	Glycosyl transferase, family 2
BCV59_RS25835	COG1045	serine acetyltransferase
BCV59_RS25840	COG0438	transferase activity, transferring glycosyl groups
BCV59_RS25850	COG1216	Glycosyl transferase, family 2
BCV59_RS25860	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BCV59_RS25865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV59_RS25870	COG1051	belongs to the nudix hydrolase family
BCV59_RS25875	COG0297	glycogen (starch) synthase activity
BCV59_RS25880	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BCV59_RS25880	COG0662	Cupin 2, conserved barrel domain protein
BCV59_RS25885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV59_RS25890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BCV59_RS25895	COG2244	polysaccharide biosynthetic process
BCV59_RS25900	COG2327	Polysaccharide pyruvyl transferase
BCV59_RS25905	COG0438	transferase activity, transferring glycosyl groups
BCV59_RS25915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCV59_RS25925	COG2089	acid synthase
BCV59_RS25995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCV59_RS26000	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCV59_RS26025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCV59_RS26030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCV59_RS26030	COG0131	Imidazoleglycerol-phosphate dehydratase
BCV59_RS26040	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCV59_RS26050	COG2161	toxin-antitoxin pair type II binding
BCV59_RS26055	COG4115	mRNA cleavage
BCV59_RS26060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV59_RS26065	COG0583	DNA-binding transcription factor activity
BCV59_RS26070	COG0531	amino acid
BCV59_RS26075	COG2391	methyltransferase activity
BCV59_RS26080	COG0425	Belongs to the sulfur carrier protein TusA family
BCV59_RS26085	COG2925	Exonuclease
BCV59_RS26090	COG1686	Belongs to the peptidase S11 family
BCV59_RS26100	COG1289	transmembrane transporter activity
BCV59_RS26110	COG4917	ethanolamine utilization protein
BCV59_RS26125	COG0405	Gamma-glutamyltransferase
BCV59_RS26130	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BCV59_RS26165	COG4771	TonB-dependent receptor
BCV59_RS26175	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BCV59_RS26190	COG1376	ErfK ybiS ycfS ynhG family protein
BCV59_RS26200	COG0583	DNA-binding transcription factor activity
BCV59_RS26205	COG0583	DNA-binding transcription factor activity
BCV59_RS26215	COG0534	Mate efflux family protein
BCV59_RS26225	COG0217	transcriptional regulatory protein
BCV59_RS26240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCV59_RS26255	COG1470	cell adhesion involved in biofilm formation
BCV59_RS26255	COG1388	LysM domain
BCV59_RS26285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV59_RS26295	COG1396	sequence-specific DNA binding
BCV59_RS26320	COG1846	Transcriptional regulator
BCV59_RS26350	COG4372	Transposase
BCV59_RS26355	COG3436	PFAM IS66 Orf2 family protein
BCV59_RS26440	COG2032	superoxide dismutase activity
BCV59_RS26455	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS26515	COG2850	peptidyl-arginine hydroxylation
BCV59_RS26520	COG2205	protein histidine kinase activity
BCV59_RS26530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCV59_RS26550	COG1187	pseudouridine synthase activity
BCV59_RS26555	COG0538	isocitrate dehydrogenase activity
BCV59_RS26560	COG0582	viral genome integration into host DNA
BCV59_RS26620	COG5562	phage envelope protein
BCV59_RS26635	COG4220	transposase activity
BCV59_RS26660	COG5301	cellulose 1,4-beta-cellobiosidase activity
BCV59_RS26665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCV59_RS26670	COG3546	catalase activity
BCV59_RS26675	COG3685	Protein conserved in bacteria
BCV59_RS26680	COG3685	Protein conserved in bacteria
BCV59_RS26685	COG3729	General stress protein
BCV59_RS26690	COG0500	methyltransferase
BCV59_RS26705	COG4571	Outer membrane protease
BCV59_RS26715	COG0456	acetyltransferase
BCV59_RS26730	COG5562	phage envelope protein
BCV59_RS26735	COG0789	Transcriptional regulator
BCV59_RS26740	COG2200	EAL domain
BCV59_RS26765	COG2200	EAL domain
BCV59_RS26815	COG2894	cell division
BCV59_RS26840	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCV59_RS26855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV59_RS26860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCV59_RS26880	COG2719	SpoVR family
BCV59_RS26890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCV59_RS26910	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BCV59_RS26930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV59_RS26930	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BCV59_RS26930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV59_RS26935	COG1461	Dihydroxyacetone kinase
BCV59_RS26940	COG2376	Dihydroxyacetone kinase
BCV59_RS26945	COG3284	Transcriptional regulator
BCV59_RS26950	COG3468	outer membrane autotransporter barrel domain protein
BCV59_RS26960	COG0012	GTP binding
BCV59_RS26975	COG0659	secondary active sulfate transmembrane transporter activity
BCV59_RS26980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCV59_RS27005	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV59_RS27010	COG3094	Invasion gene expression up-regulator, SirB
BCV59_RS27015	COG2912	Transglutaminase-like superfamily
BCV59_RS27035	COG0387	Pfam Sodium calcium exchanger
BCV59_RS27040	COG4572	Cation transport regulator
BCV59_RS27045	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BCV59_RS27050	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BCV59_RS27055	COG4932	domain protein
BCV59_RS27060	COG2197	response regulator
BCV59_RS27065	COG3850	Histidine kinase
BCV59_RS27075	COG2223	nitrite transmembrane transporter activity
BCV59_RS27080	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCV59_RS27085	COG1140	nitrate reductase beta subunit
BCV59_RS27090	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCV59_RS27095	COG2181	nitrate reductase activity
BCV59_RS27110	COG0788	formyltetrahydrofolate deformylase activity
BCV59_RS27120	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV59_RS27125	COG0745	RESPONSE REGULATOR receiver
BCV59_RS27130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCV59_RS27140	COG1435	thymidine kinase activity
BCV59_RS27145	COG1454	alcohol dehydrogenase
BCV59_RS27145	COG1012	belongs to the aldehyde dehydrogenase family
BCV59_RS27150	COG2095	MarC family integral membrane protein
BCV59_RS27155	COG4166	transmembrane transport
BCV59_RS27160	COG0601	transmembrane transport
BCV59_RS27165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV59_RS27170	COG0444	Belongs to the ABC transporter superfamily
BCV59_RS27175	COG4608	Belongs to the ABC transporter superfamily
BCV59_RS27195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV59_RS27200	COG2350	Protein conserved in bacteria
BCV59_RS27205	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BCV59_RS27210	COG1607	acyl-coa hydrolase
BCV59_RS27225	COG3047	cAMP biosynthetic process
BCV59_RS27230	COG0582	viral genome integration into host DNA
BCV59_RS27260	COG1846	Transcriptional regulator
BCV59_RS27285	COG1403	HNH endonuclease
BCV59_RS27290	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BCV59_RS27340	COG3772	lysozyme
BCV59_RS27445	COG0582	viral genome integration into host DNA
BCV59_RS27460	COG3328	transposase activity
BCV59_RS27465	COG3328	transposase activity
BCV59_RS27500	COG0582	viral genome integration into host DNA
BCV59_RS27545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV59_RS27570	COG1484	DNA-dependent DNA replication
BCV59_RS27575	COG0305	Participates in initiation and elongation during chromosome replication
BCV59_RS27585	COG1403	HNH endonuclease