locus-tag	class	description
HGG68_RS00015	COG0460	homoserine dehydrogenase
HGG68_RS00015	COG0527	aspartate kinase activity
HGG68_RS00020	COG0083	homoserine kinase activity
HGG68_RS00025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HGG68_RS00040	COG1115	amino acid carrier protein
HGG68_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
HGG68_RS00055	COG1584	GPR1 FUN34 yaaH family protein
HGG68_RS00060	COG4735	regulation of single-species biofilm formation
HGG68_RS00090	COG3119	arylsulfatase activity
HGG68_RS00105	COG0583	DNA-binding transcription factor activity
HGG68_RS00120	COG0196	riboflavin kinase activity
HGG68_RS00135	COG1047	Peptidyl-prolyl cis-trans
HGG68_RS00160	COG0505	Belongs to the CarA family
HGG68_RS00165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HGG68_RS00215	COG0644	oxidoreductase
HGG68_RS00220	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HGG68_RS00225	COG2271	Major facilitator Superfamily
HGG68_RS00235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HGG68_RS00235	COG0475	glutathione-regulated potassium exporter activity
HGG68_RS00240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGG68_RS00270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HGG68_RS00275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HGG68_RS00285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HGG68_RS00290	COG0564	pseudouridine synthase activity
HGG68_RS00300	COG0417	DNA replication proofreading
HGG68_RS00310	COG0235	Class ii aldolase
HGG68_RS00315	COG2160	L-arabinose isomerase activity
HGG68_RS00320	COG1069	ribulokinase activity
HGG68_RS00325	COG4977	sequence-specific DNA binding
HGG68_RS00345	COG0586	Pfam SNARE associated Golgi protein
HGG68_RS00350	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HGG68_RS00355	COG1178	ABC-type Fe3 transport system permease component
HGG68_RS00360	COG4143	(ABC) transporter
HGG68_RS00390	COG0473	3-isopropylmalate dehydrogenase activity
HGG68_RS00405	COG0583	DNA-binding transcription factor activity
HGG68_RS00415	COG0028	Belongs to the TPP enzyme family
HGG68_RS00420	COG0440	acetolactate synthase activity
HGG68_RS00430	COG1609	Transcriptional regulator
HGG68_RS00440	COG0275	rRNA processing
HGG68_RS00445	COG3116	cell division
HGG68_RS00450	COG0768	penicillin binding
HGG68_RS00455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGG68_RS00460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HGG68_RS00470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGG68_RS00475	COG0772	Belongs to the SEDS family
HGG68_RS00490	COG1181	Belongs to the D-alanine--D-alanine ligase family
HGG68_RS00495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HGG68_RS00500	COG0849	cell division
HGG68_RS00505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGG68_RS00525	COG0494	nUDIX hydrolase
HGG68_RS00535	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HGG68_RS00545	COG0237	dephospho-CoA kinase activity
HGG68_RS00560	COG1459	type II secretion system
HGG68_RS00565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HGG68_RS00570	COG4969	Belongs to the N-Me-Phe pilin family
HGG68_RS00575	COG0157	Belongs to the NadC ModD family
HGG68_RS00580	COG3023	N-Acetylmuramoyl-L-alanine amidase
HGG68_RS00585	COG3725	Membrane protein required for beta-lactamase induction
HGG68_RS00590	COG1113	amino acid transport
HGG68_RS00595	COG3157	Type VI secretion system effector, Hcp
HGG68_RS00625	COG2186	Transcriptional regulator
HGG68_RS00630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HGG68_RS00635	COG0508	dehydrogenase complex catalyzes the overall conversion of
HGG68_RS00640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGG68_RS00645	COG3064	Membrane
HGG68_RS00650	COG1049	propionate catabolic process, 2-methylcitrate cycle
HGG68_RS00675	COG2132	Multicopper oxidase
HGG68_RS00680	COG4993	Dehydrogenase
HGG68_RS00685	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HGG68_RS00690	COG0288	reversible hydration of carbon dioxide
HGG68_RS00695	COG1131	(ABC) transporter
HGG68_RS00700	COG0842	Transport permease protein
HGG68_RS00705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS00710	COG0726	polysaccharide deacetylase
HGG68_RS00720	COG5464	transposase or invertase
HGG68_RS00730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HGG68_RS00740	COG3539	Fimbrial protein
HGG68_RS00745	COG3539	Fimbrial protein
HGG68_RS00750	COG3539	Fimbrial protein
HGG68_RS00755	COG3539	Fimbrial protein
HGG68_RS00760	COG3188	usher protein
HGG68_RS00765	COG3121	Chaperone
HGG68_RS00770	COG3539	Fimbrial protein
HGG68_RS00775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HGG68_RS00780	COG0617	tRNA 3'-terminal CCA addition
HGG68_RS00785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGG68_RS00790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HGG68_RS00800	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HGG68_RS00805	COG1643	Atp-dependent helicase
HGG68_RS00810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HGG68_RS00815	COG4774	siderophore transport
HGG68_RS00820	COG1120	ATPase activity
HGG68_RS00825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HGG68_RS00830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS00855	COG2860	membrane
HGG68_RS00860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HGG68_RS00875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGG68_RS00885	COG3835	regulator
HGG68_RS00895	COG2171	N-acyltransferase activity
HGG68_RS00900	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HGG68_RS00905	COG0024	Methionine aminopeptidase
HGG68_RS00930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HGG68_RS00940	COG0575	Belongs to the CDS family
HGG68_RS00945	COG0750	zinc metalloprotease
HGG68_RS00955	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HGG68_RS00960	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HGG68_RS00980	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGG68_RS00985	COG0587	DNA-directed DNA polymerase activity
HGG68_RS00995	COG1982	Orn Lys Arg decarboxylase major
HGG68_RS01000	COG0346	lactoylglutathione lyase activity
HGG68_RS01010	COG4568	rho-dependent transcription termination
HGG68_RS01020	COG4681	YaeQ
HGG68_RS01025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGG68_RS01030	COG3015	lipoprotein NlpE involved in copper resistance
HGG68_RS01040	COG0791	NLP P60 protein
HGG68_RS01050	COG1720	tRNA m6t6A37 methyltransferase activity
HGG68_RS01060	COG1464	Belongs to the NlpA lipoprotein family
HGG68_RS01065	COG2011	ABC-type metal ion transport system permease component
HGG68_RS01070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGG68_RS01075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HGG68_RS01110	COG0656	L-ascorbic acid biosynthetic process
HGG68_RS01115	COG0583	DNA-binding transcription factor activity
HGG68_RS01125	COG2226	methyltransferase
HGG68_RS01130	COG1388	LysM domain
HGG68_RS01130	COG0741	lytic transglycosylase activity
HGG68_RS01135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HGG68_RS01140	COG2226	methyltransferase
HGG68_RS01150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HGG68_RS01170	COG3436	PFAM IS66 Orf2 family protein
HGG68_RS01180	COG3547	Transposase (IS116 IS110 IS902 family)
HGG68_RS01200	COG4584	PFAM Integrase catalytic
HGG68_RS01205	COG1484	DNA-dependent DNA replication
HGG68_RS01230	COG2003	Belongs to the UPF0758 family
HGG68_RS01295	COG0582	viral genome integration into host DNA
HGG68_RS01320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS01325	COG1120	ATPase activity
HGG68_RS01395	COG0823	Involved in the tonB-independent uptake of proteins
HGG68_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS01405	COG1917	Cupin 2, conserved barrel domain protein
HGG68_RS01410	COG2211	Major facilitator Superfamily
HGG68_RS01440	COG1349	DNA-binding transcription factor activity
HGG68_RS01450	COG0738	Major facilitator superfamily
HGG68_RS01465	COG3037	sugar-specific permease SgaT UlaA
HGG68_RS01475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS01505	COG3210	domain, Protein
HGG68_RS01510	COG3210	domain, Protein
HGG68_RS01530	COG3468	outer membrane autotransporter barrel domain protein
HGG68_RS01530	COG3210	domain, Protein
HGG68_RS01585	COG2197	response regulator
HGG68_RS01605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HGG68_RS01615	COG1960	acyl-CoA dehydrogenase activity
HGG68_RS01625	COG0121	glutamine amidotransferase
HGG68_RS01630	COG3034	peptidoglycan biosynthetic process
HGG68_RS01635	COG0791	NLP P60 protein
HGG68_RS01650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGG68_RS01655	COG0454	-acetyltransferase
HGG68_RS01660	COG1690	Belongs to the RtcB family
HGG68_RS01665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGG68_RS01670	COG2195	Cleaves the N-terminal amino acid of tripeptides
HGG68_RS01690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HGG68_RS01700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGG68_RS01710	COG0582	viral genome integration into host DNA
HGG68_RS01740	COG3477	response to acidic pH
HGG68_RS01750	COG0727	PFAM Uncharacterised protein family (UPF0153)
HGG68_RS01765	COG3188	usher protein
HGG68_RS01805	COG1902	pentaerythritol trinitrate reductase activity
HGG68_RS01810	COG1073	alpha beta
HGG68_RS01815	COG0583	DNA-binding transcription factor activity
HGG68_RS01825	COG0667	Aldo Keto reductase
HGG68_RS01830	COG0656	L-ascorbic acid biosynthetic process
HGG68_RS01835	COG1388	LysM domain
HGG68_RS01840	COG2207	Transcriptional regulator
HGG68_RS01840	COG3708	Transcriptional regulator
HGG68_RS01845	COG0656	L-ascorbic acid biosynthetic process
HGG68_RS01850	COG3059	membrane
HGG68_RS01860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGG68_RS01865	COG2207	Transcriptional regulator
HGG68_RS01870	COG0247	lactate metabolic process
HGG68_RS01875	COG1139	Iron-sulfur cluster binding protein
HGG68_RS01880	COG1556	Lactate utilization protein
HGG68_RS01890	COG3468	outer membrane autotransporter barrel domain protein
HGG68_RS01905	COG2200	EAL domain
HGG68_RS01905	COG2771	luxR family
HGG68_RS01910	COG0582	viral genome integration into host DNA
HGG68_RS01915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HGG68_RS01920	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS01930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HGG68_RS01935	COG2200	EAL domain
HGG68_RS01935	COG2771	luxR family
HGG68_RS01940	COG0583	DNA-binding transcription factor activity
HGG68_RS01950	COG0666	response to abiotic stimulus
HGG68_RS01960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGG68_RS01965	COG1304	FMN binding
HGG68_RS01975	COG0549	Belongs to the carbamate kinase family
HGG68_RS01980	COG0402	S-adenosylhomocysteine deaminase activity
HGG68_RS01985	COG1064	alcohol dehydrogenase
HGG68_RS01995	COG1280	lysine exporter protein (LysE YggA)
HGG68_RS02005	COG3829	transcription factor binding
HGG68_RS02010	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HGG68_RS02015	COG0372	Belongs to the citrate synthase family
HGG68_RS02020	COG2079	MmgE PrpD family protein
HGG68_RS02025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HGG68_RS02030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HGG68_RS02035	COG0402	S-adenosylhomocysteine deaminase activity
HGG68_RS02040	COG0110	maltose O-acetyltransferase activity
HGG68_RS02045	COG2223	nitrite transmembrane transporter activity
HGG68_RS02050	COG3250	beta-galactosidase activity
HGG68_RS02055	COG1609	Transcriptional regulator
HGG68_RS02065	COG3122	Protein conserved in bacteria
HGG68_RS02070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HGG68_RS02095	COG1215	transferase activity, transferring glycosyl groups
HGG68_RS02100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HGG68_RS02105	COG4521	taurine ABC transporter
HGG68_RS02110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HGG68_RS02115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGG68_RS02120	COG2175	clavaminate synthase activity
HGG68_RS02125	COG0113	porphobilinogen synthase activity
HGG68_RS02130	COG3468	outer membrane autotransporter barrel domain protein
HGG68_RS02135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGG68_RS02140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HGG68_RS02145	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HGG68_RS02165	COG1181	Belongs to the D-alanine--D-alanine ligase family
HGG68_RS02180	COG1785	Belongs to the alkaline phosphatase family
HGG68_RS02190	COG3706	GGDEF domain
HGG68_RS02195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGG68_RS02215	COG4126	flavin adenine dinucleotide binding
HGG68_RS02240	COG1940	carbohydrate kinase activity
HGG68_RS02245	COG2814	Major facilitator Superfamily
HGG68_RS02250	COG0419	ATPase involved in DNA repair
HGG68_RS02255	COG0420	3'-5' exonuclease activity
HGG68_RS02260	COG0745	RESPONSE REGULATOR receiver
HGG68_RS02265	COG5002	protein histidine kinase activity
HGG68_RS02270	COG1114	Component of the transport system for branched-chain amino acids
HGG68_RS02275	COG1113	amino acid transport
HGG68_RS02280	COG0366	Alpha amylase catalytic
HGG68_RS02285	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HGG68_RS02290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HGG68_RS02300	COG1862	Preprotein translocase
HGG68_RS02305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGG68_RS02310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGG68_RS02315	COG1403	HNH endonuclease
HGG68_RS02320	COG3248	Nucleoside-binding outer membrane protein
HGG68_RS02325	COG4238	major outer membrane lipoprotein
HGG68_RS02335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGG68_RS02335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGG68_RS02350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HGG68_RS02355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HGG68_RS02360	COG0667	Aldo Keto reductase
HGG68_RS02370	COG0142	geranyltranstransferase activity
HGG68_RS02385	COG0693	protein deglycase activity
HGG68_RS02390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGG68_RS02400	COG2814	Major facilitator Superfamily
HGG68_RS02410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HGG68_RS02415	COG1845	cytochrome c oxidase, subunit III
HGG68_RS02420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGG68_RS02425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HGG68_RS02430	COG2223	nitrite transmembrane transporter activity
HGG68_RS02435	COG3056	Lipoprotein
HGG68_RS02440	COG0271	Belongs to the BolA IbaG family
HGG68_RS02460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HGG68_RS02465	COG0776	regulation of translation
HGG68_RS02470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HGG68_RS02475	COG1555	photosystem II stabilization
HGG68_RS02480	COG0824	Thioesterase
HGG68_RS02490	COG4533	DNA binding
HGG68_RS02495	COG0561	phosphatase activity
HGG68_RS02505	COG1522	sequence-specific DNA binding
HGG68_RS02510	COG1132	(ABC) transporter
HGG68_RS02515	COG1132	(ABC) transporter
HGG68_RS02520	COG0347	Belongs to the P(II) protein family
HGG68_RS02525	COG0004	ammonium transporteR
HGG68_RS02530	COG1946	Acyl-CoA thioesterase
HGG68_RS02535	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HGG68_RS02540	COG3695	enzyme binding
HGG68_RS02550	COG5507	3-demethylubiquinone-9 3-methyltransferase
HGG68_RS02555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HGG68_RS02565	COG0110	maltose O-acetyltransferase activity
HGG68_RS02580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGG68_RS02585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS02590	COG1309	transcriptional regulator
HGG68_RS02595	COG3264	Mechanosensitive ion channel
HGG68_RS02595	COG1196	nuclear chromosome segregation
HGG68_RS02605	COG3923	Primosomal replication protein n
HGG68_RS02610	COG2832	Protein of unknown function (DUF454)
HGG68_RS02620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGG68_RS02650	COG0657	acetylesterase activity
HGG68_RS02655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS02660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HGG68_RS02660	COG4651	solute:proton antiporter activity
HGG68_RS02665	COG2223	nitrite transmembrane transporter activity
HGG68_RS02670	COG0737	Belongs to the 5'-nucleotidase family
HGG68_RS02675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGG68_RS02680	COG3735	TraB family
HGG68_RS02690	COG3093	addiction module antidote protein HigA
HGG68_RS02695	COG2217	Heavy metal translocating P-type atpase
HGG68_RS02700	COG2066	Belongs to the glutaminase family
HGG68_RS02705	COG0531	amino acid
HGG68_RS02710	COG0789	Transcriptional regulator
HGG68_RS02720	COG1585	Membrane protein implicated in regulation of membrane protease activity
HGG68_RS02725	COG0330	HflC and HflK could
HGG68_RS02730	COG4619	ABC transporter
HGG68_RS02735	COG0390	transport system, permease component
HGG68_RS02740	COG3118	belongs to the thioredoxin family
HGG68_RS02745	COG0300	oxidoreductase activity
HGG68_RS02750	COG2755	lipolytic protein G-D-S-L family
HGG68_RS02755	COG4181	ATPase activity
HGG68_RS02760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HGG68_RS02775	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HGG68_RS02780	COG1414	Transcriptional regulator
HGG68_RS02785	COG3960	tartronate-semialdehyde synthase activity
HGG68_RS02790	COG3622	Belongs to the hyi family
HGG68_RS02795	COG2084	Dehydrogenase
HGG68_RS02800	COG1953	Uracil, thiamine, allantoin
HGG68_RS02810	COG2233	PERMEase
HGG68_RS02815	COG1929	Belongs to the glycerate kinase type-1 family
HGG68_RS02820	COG3257	ureidoglycine aminohydrolase activity
HGG68_RS02825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HGG68_RS02830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HGG68_RS02835	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGG68_RS02840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGG68_RS02850	COG0549	Belongs to the carbamate kinase family
HGG68_RS02855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGG68_RS02860	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGG68_RS02870	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HGG68_RS02875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGG68_RS02890	COG2501	S4 domain
HGG68_RS02920	COG0500	methyltransferase
HGG68_RS02925	COG4571	Outer membrane protease
HGG68_RS02935	COG4783	chaperone-mediated protein folding
HGG68_RS02945	COG5002	protein histidine kinase activity
HGG68_RS02950	COG0745	RESPONSE REGULATOR receiver
HGG68_RS02955	COG1538	Outer membrane efflux protein
HGG68_RS02960	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS02965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS02970	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGG68_RS02975	COG1113	amino acid transport
HGG68_RS02980	COG0668	transmembrane transport
HGG68_RS02985	COG0778	Nitroreductase
HGG68_RS02990	COG2315	Protein conserved in bacteria
HGG68_RS03000	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HGG68_RS03010	COG2977	Belongs to the P-Pant transferase superfamily
HGG68_RS03015	COG4771	TonB-dependent receptor
HGG68_RS03020	COG2382	esterase
HGG68_RS03025	COG3251	PFAM MbtH domain protein
HGG68_RS03030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HGG68_RS03030	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HGG68_RS03035	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HGG68_RS03040	COG1120	ATPase activity
HGG68_RS03045	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS03050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS03060	COG4592	Periplasmic binding protein
HGG68_RS03065	COG1169	isochorismate synthase
HGG68_RS03070	COG1021	2,3-dihydroxybenzoate-AMP ligase
HGG68_RS03075	COG1535	isochorismatase
HGG68_RS03075	COG3433	isochorismatase activity
HGG68_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS03085	COG2050	protein possibly involved in aromatic compounds catabolism
HGG68_RS03090	COG1966	Carbon starvation protein
HGG68_RS03095	COG2879	small protein
HGG68_RS03100	COG0371	Dehydrogenase
HGG68_RS03105	COG0436	Aminotransferase
HGG68_RS03110	COG1475	DNA binding
HGG68_RS03115	COG3969	phosphoadenosine phosphosulfate
HGG68_RS03120	COG0583	DNA-binding transcription factor activity
HGG68_RS03125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HGG68_RS03130	COG0450	alkyl hydroperoxide reductase
HGG68_RS03135	COG3634	alkyl hydroperoxide reductase activity
HGG68_RS03140	COG0589	response to stress
HGG68_RS03145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HGG68_RS03150	COG3719	Belongs to the RNase T2 family
HGG68_RS03155	COG0471	metal ion transport
HGG68_RS03170	COG3051	citrate lyase alpha subunit
HGG68_RS03175	COG2301	Belongs to the HpcH HpaI aldolase family
HGG68_RS03185	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HGG68_RS03190	COG3290	protein histidine kinase activity
HGG68_RS03195	COG4565	transcriptional regulatory protein
HGG68_RS03200	COG3069	C4-dicarboxylate transmembrane transporter activity
HGG68_RS03220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HGG68_RS03225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGG68_RS03250	COG1686	Belongs to the peptidase S11 family
HGG68_RS03255	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HGG68_RS03260	COG0772	Belongs to the SEDS family
HGG68_RS03265	COG0768	penicillin binding
HGG68_RS03275	COG0799	negative regulation of ribosome biogenesis
HGG68_RS03280	COG0406	alpha-ribazole phosphatase activity
HGG68_RS03290	COG1466	dna polymerase III delta subunit
HGG68_RS03305	COG2888	peptidyl-tyrosine sulfation
HGG68_RS03315	COG1126	abc transporter atp-binding protein
HGG68_RS03320	COG0765	amino acid transport
HGG68_RS03325	COG0765	amino acid transport
HGG68_RS03330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS03340	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HGG68_RS03345	COG4535	Mg2 and Co2 transporter CorC
HGG68_RS03355	COG1702	phosphate starvation-inducible protein PhoH
HGG68_RS03365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGG68_RS03405	COG0367	asparagine synthase
HGG68_RS03410	COG0647	UMP catabolic process
HGG68_RS03415	COG1846	Transcriptional regulator
HGG68_RS03415	COG1940	carbohydrate kinase activity
HGG68_RS03420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGG68_RS03425	COG0363	glucosamine-6-phosphate deaminase activity
HGG68_RS03430	COG1263	PTS System
HGG68_RS03430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS03430	COG2190	(PTS) system
HGG68_RS03450	COG0861	Integral membrane protein TerC family
HGG68_RS03455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGG68_RS03460	COG1454	alcohol dehydrogenase
HGG68_RS03465	COG3395	kinase activity
HGG68_RS03470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HGG68_RS03475	COG1349	DNA-binding transcription factor activity
HGG68_RS03500	COG0735	belongs to the Fur family
HGG68_RS03510	COG0716	FMN binding
HGG68_RS03520	COG0596	Alpha beta hydrolase
HGG68_RS03525	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HGG68_RS03530	COG0033	Phosphoglucomutase
HGG68_RS03535	COG0531	amino acid
HGG68_RS03540	COG1982	Orn Lys Arg decarboxylase major
HGG68_RS03550	COG0745	RESPONSE REGULATOR receiver
HGG68_RS03555	COG2205	protein histidine kinase activity
HGG68_RS03570	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HGG68_RS03585	COG3272	Protein of unknown function (DUF1722)
HGG68_RS03590	COG0415	Belongs to the DNA photolyase family
HGG68_RS03600	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGG68_RS03605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HGG68_RS03610	COG1984	allophanate hydrolase subunit 2
HGG68_RS03615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HGG68_RS03625	COG3180	Ammonia monooxygenase
HGG68_RS03635	COG0372	Belongs to the citrate synthase family
HGG68_RS03645	COG2009	succinate dehydrogenase
HGG68_RS03650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HGG68_RS03655	COG1053	succinate dehydrogenase
HGG68_RS03660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HGG68_RS03665	COG0567	Dehydrogenase, E1 component
HGG68_RS03670	COG0508	dehydrogenase complex catalyzes the overall conversion of
HGG68_RS03680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGG68_RS03690	COG1271	oxidase subunit
HGG68_RS03695	COG1294	oxidase, subunit
HGG68_RS03700	COG4890	Cyd operon protein YbgT
HGG68_RS03705	COG3790	cyd operon protein YbgE
HGG68_RS03710	COG0824	Thioesterase
HGG68_RS03715	COG0811	peptide transport
HGG68_RS03720	COG0848	biopolymer transport protein
HGG68_RS03725	COG3064	Membrane
HGG68_RS03735	COG2885	chlorophyll binding
HGG68_RS03740	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HGG68_RS03780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HGG68_RS03785	COG3201	nicotinamide mononucleotide transporter
HGG68_RS03800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HGG68_RS03810	COG2017	converts alpha-aldose to the beta-anomer
HGG68_RS03820	COG1085	galactose-1-phosphate uridylyltransferase
HGG68_RS03825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HGG68_RS03830	COG1119	ATPase activity
HGG68_RS03835	COG2005	Transcriptional regulator
HGG68_RS03835	COG3585	molybdate ion transport
HGG68_RS03845	COG0725	ABC transporter, periplasmic molybdate-binding protein
HGG68_RS03850	COG4149	molybdate abc transporter
HGG68_RS03855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HGG68_RS03860	COG0561	phosphatase activity
HGG68_RS03870	COG0583	DNA-binding transcription factor activity
HGG68_RS03875	COG2828	Protein conserved in bacteria
HGG68_RS03880	COG0471	metal ion transport
HGG68_RS03885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HGG68_RS03890	COG4677	pectinesterase activity
HGG68_RS03910	COG1132	(ABC) transporter
HGG68_RS03915	COG4977	sequence-specific DNA binding
HGG68_RS03920	COG1881	PFAM PEBP family protein
HGG68_RS03930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HGG68_RS03940	COG0156	8-amino-7-oxononanoate synthase activity
HGG68_RS03945	COG2226	methyltransferase
HGG68_RS03950	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HGG68_RS03960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HGG68_RS03970	COG0521	Mo-molybdopterin cofactor biosynthetic process
HGG68_RS03980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HGG68_RS03985	COG0314	molybdopterin synthase activity
HGG68_RS03990	COG0670	Belongs to the BI1 family
HGG68_RS03995	COG0670	Belongs to the BI1 family
HGG68_RS04000	COG0392	lysyltransferase activity
HGG68_RS04005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGG68_RS04010	COG3568	Endonuclease Exonuclease Phosphatase
HGG68_RS04020	COG0842	Transport permease protein
HGG68_RS04025	COG0842	Transport permease protein
HGG68_RS04030	COG1131	(ABC) transporter
HGG68_RS04040	COG1309	transcriptional regulator
HGG68_RS04045	COG0513	Belongs to the DEAD box helicase family
HGG68_RS04055	COG1199	ATP-dependent helicase activity
HGG68_RS04060	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGG68_RS04065	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HGG68_RS04075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HGG68_RS04080	COG3128	pkhd-type hydroxylase
HGG68_RS04085	COG4774	siderophore transport
HGG68_RS04095	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HGG68_RS04100	COG0668	transmembrane transport
HGG68_RS04105	COG1126	abc transporter atp-binding protein
HGG68_RS04110	COG0765	amino acid transport
HGG68_RS04115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS04120	COG0783	Belongs to the Dps family
HGG68_RS04125	COG5006	permease, DMT superfamily
HGG68_RS04135	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HGG68_RS04140	COG2194	sulfuric ester hydrolase activity
HGG68_RS04150	COG1321	iron dependent repressor
HGG68_RS04155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGG68_RS04160	COG1376	ErfK ybiS ycfS ynhG family protein
HGG68_RS04165	COG0488	(ABC) transporter
HGG68_RS04170	COG0561	phosphatase activity
HGG68_RS04175	COG1882	Formate acetyltransferase
HGG68_RS04180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGG68_RS04185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGG68_RS04190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HGG68_RS04195	COG0303	'Molybdopterin
HGG68_RS04200	COG1446	asparaginase
HGG68_RS04205	COG4172	Belongs to the ABC transporter superfamily
HGG68_RS04215	COG0601	transmembrane transport
HGG68_RS04225	COG2200	EAL domain
HGG68_RS04230	COG2199	diguanylate cyclase activity
HGG68_RS04245	COG2133	pyrroloquinoline quinone binding
HGG68_RS04250	COG0625	glutathione transferase activity
HGG68_RS04255	COG1686	Belongs to the peptidase S11 family
HGG68_RS04260	COG1349	DNA-binding transcription factor activity
HGG68_RS04265	COG0671	phosphoesterase, PA-phosphatase related
HGG68_RS04270	COG2814	Major facilitator Superfamily
HGG68_RS04280	COG0561	phosphatase activity
HGG68_RS04285	COG0738	Major facilitator superfamily
HGG68_RS04290	COG3226	Transcriptional regulator
HGG68_RS04300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HGG68_RS04340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HGG68_RS04380	COG4695	Portal protein
HGG68_RS04530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HGG68_RS04540	COG0778	Nitroreductase
HGG68_RS04555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HGG68_RS04560	COG3842	ATPase activity
HGG68_RS04565	COG1176	ABC-type spermidine putrescine transport system, permease component I
HGG68_RS04570	COG1177	transmembrane transport
HGG68_RS04580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGG68_RS04585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS04590	COG4160	amino acid transport
HGG68_RS04595	COG4215	(ABC) transporter
HGG68_RS04600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS04605	COG1126	abc transporter atp-binding protein
HGG68_RS04620	COG3023	N-Acetylmuramoyl-L-alanine amidase
HGG68_RS04625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGG68_RS04630	COG0702	epimerase
HGG68_RS04635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HGG68_RS04640	COG0028	Belongs to the TPP enzyme family
HGG68_RS04645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGG68_RS04650	COG1151	hydroxylamine reductase activity
HGG68_RS04655	COG2431	L-lysine efflux transmembrane transporter activity
HGG68_RS04665	COG3593	DNA synthesis involved in DNA repair
HGG68_RS04670	COG2990	Protein conserved in bacteria
HGG68_RS04675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS04685	COG1278	Cold shock
HGG68_RS04695	COG0542	response to heat
HGG68_RS04715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HGG68_RS04720	COG4988	ABC transporter
HGG68_RS04725	COG0492	ferredoxin-NADP+ reductase activity
HGG68_RS04730	COG1522	sequence-specific DNA binding
HGG68_RS04735	COG1674	ftsk spoiiie
HGG68_RS04735	COG1178	ABC-type Fe3 transport system permease component
HGG68_RS04745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HGG68_RS04755	COG0243	molybdopterin cofactor binding
HGG68_RS04760	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS04765	COG3302	dmso reductase anchor subunit
HGG68_RS04770	COG1335	isochorismatase
HGG68_RS04780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGG68_RS04785	COG1882	Formate acetyltransferase
HGG68_RS04790	COG2116	formate transmembrane transporter activity
HGG68_RS04795	COG1944	ATP diphosphatase activity
HGG68_RS04800	COG2323	membrane
HGG68_RS04810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HGG68_RS04815	COG0501	Belongs to the peptidase M48B family
HGG68_RS04825	COG0539	negative regulation of cytoplasmic translation
HGG68_RS04835	COG0658	competence protein
HGG68_RS04835	COG2333	competence protein COMEC
HGG68_RS04850	COG3214	Protein conserved in bacteria
HGG68_RS04860	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HGG68_RS04865	COG3173	Aminoglycoside phosphotransferase
HGG68_RS04870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HGG68_RS04875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGG68_RS04885	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HGG68_RS04890	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HGG68_RS04895	COG2989	Protein conserved in bacteria
HGG68_RS04900	COG3108	Peptidase M15
HGG68_RS04905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HGG68_RS04910	COG1448	Aminotransferase
HGG68_RS04930	COG0308	aminopeptidase N
HGG68_RS04935	COG1116	anion transmembrane transporter activity
HGG68_RS04940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGG68_RS04945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGG68_RS04950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGG68_RS04955	COG0431	NADPH-dependent FMN reductase
HGG68_RS04970	COG3217	Mosc domain protein beta barrel domain protein
HGG68_RS04970	COG0633	Ferredoxin
HGG68_RS04975	COG0116	Belongs to the methyltransferase superfamily
HGG68_RS04975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HGG68_RS04980	COG0488	(ABC) transporter
HGG68_RS04985	COG2995	paraquat-inducible protein a
HGG68_RS04990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HGG68_RS04990	COG3008	intermembrane lipid transfer
HGG68_RS04995	COG3009	Protein conserved in bacteria
HGG68_RS05000	COG3130	regulation of translation
HGG68_RS05010	COG1067	ATP-dependent peptidase activity
HGG68_RS05030	COG3070	regulator of competence-specific genes
HGG68_RS05035	COG1289	transmembrane transporter activity
HGG68_RS05040	COG3304	Inner membrane component domain
HGG68_RS05045	COG0210	DNA helicase
HGG68_RS05060	COG1832	CoA-binding protein
HGG68_RS05075	COG1254	Belongs to the acylphosphatase family
HGG68_RS05080	COG2920	part of a sulfur-relay system
HGG68_RS05085	COG0670	Belongs to the BI1 family
HGG68_RS05095	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HGG68_RS05100	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HGG68_RS05105	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HGG68_RS05110	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HGG68_RS05115	COG1999	signal sequence binding
HGG68_RS05120	COG1773	rubredoxin
HGG68_RS05125	COG1271	oxidase subunit
HGG68_RS05130	COG1294	oxidase, subunit
HGG68_RS05145	COG1278	Cold shock
HGG68_RS05150	COG1278	Cold shock
HGG68_RS05170	COG0348	domain, Protein
HGG68_RS05175	COG0784	Response regulator, receiver
HGG68_RS05175	COG2198	Histidine kinase
HGG68_RS05175	COG2205	protein histidine kinase activity
HGG68_RS05180	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS05185	COG0745	RESPONSE REGULATOR receiver
HGG68_RS05190	COG3005	denitrification pathway
HGG68_RS05195	COG0243	molybdopterin cofactor binding
HGG68_RS05200	COG3381	protein complex oligomerization
HGG68_RS05230	COG3729	General stress protein
HGG68_RS05235	COG2233	PERMEase
HGG68_RS05240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGG68_RS05245	COG0778	Nitroreductase
HGG68_RS05250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGG68_RS05260	COG1335	isochorismatase
HGG68_RS05265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGG68_RS05270	COG1309	transcriptional regulator
HGG68_RS05275	COG0506	proline dehydrogenase activity
HGG68_RS05275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HGG68_RS05275	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HGG68_RS05285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGG68_RS05290	COG0672	)-iron permease
HGG68_RS05295	COG2822	iron ion transport
HGG68_RS05305	COG1702	phosphate starvation-inducible protein PhoH
HGG68_RS05310	COG3658	cytochrome
HGG68_RS05315	COG1215	transferase activity, transferring glycosyl groups
HGG68_RS05325	COG0457	Tetratricopeptide repeat
HGG68_RS05330	COG3706	GGDEF domain
HGG68_RS05335	COG0582	viral genome integration into host DNA
HGG68_RS05355	COG4983	Phage plasmid primase, P4 family domain protein
HGG68_RS05380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HGG68_RS05390	COG2222	sugar isomerase
HGG68_RS05410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HGG68_RS05415	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS05425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HGG68_RS05450	COG1216	Glycosyl transferase, family 2
HGG68_RS05455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HGG68_RS05470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGG68_RS05480	COG0204	Acyl-transferase
HGG68_RS05510	COG3210	domain, Protein
HGG68_RS05515	COG3210	domain, Protein
HGG68_RS05555	COG4644	lycopene metabolic process
HGG68_RS05560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HGG68_RS05585	COG2994	toxin metabolic process
HGG68_RS05640	COG3539	Fimbrial protein
HGG68_RS05680	COG3335	DDE superfamily endonuclease
HGG68_RS05685	COG4771	TonB-dependent receptor
HGG68_RS05690	COG2819	hydrolase of the alpha beta superfamily
HGG68_RS05695	COG2382	esterase
HGG68_RS05750	COG4771	TonB-dependent receptor
HGG68_RS05760	COG0523	cobalamin synthesis protein
HGG68_RS05805	COG3468	outer membrane autotransporter barrel domain protein
HGG68_RS05810	COG2020	methyltransferase activity
HGG68_RS05835	COG2003	Belongs to the UPF0758 family
HGG68_RS05840	COG4584	PFAM Integrase catalytic
HGG68_RS05845	COG1484	DNA-dependent DNA replication
HGG68_RS05895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HGG68_RS05905	COG3381	protein complex oligomerization
HGG68_RS05915	COG1462	curli production assembly transport component CsgG
HGG68_RS05930	COG2197	response regulator
HGG68_RS05955	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HGG68_RS05960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGG68_RS05975	COG2943	transferase activity, transferring hexosyl groups
HGG68_RS05980	COG5645	(Lipo)protein
HGG68_RS05995	COG1560	Kdo2-lipid A biosynthetic process
HGG68_RS06005	COG2353	YceI-like domain
HGG68_RS06010	COG3038	cytochrome b561
HGG68_RS06020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HGG68_RS06035	COG0418	dihydroorotase activity
HGG68_RS06045	COG2999	glutathione oxidoreductase activity
HGG68_RS06055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGG68_RS06065	COG0673	inositol 2-dehydrogenase activity
HGG68_RS06070	COG0728	peptidoglycan biosynthetic process
HGG68_RS06075	COG3418	PFAM FlgN family protein
HGG68_RS06080	COG2747	anti-sigma28 factor FlgM
HGG68_RS06085	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HGG68_RS06090	COG1815	bacterial-type flagellum-dependent cell motility
HGG68_RS06095	COG1558	bacterial-type flagellum-dependent cell motility
HGG68_RS06100	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HGG68_RS06105	COG1749	Flagellar hook protein flgE
HGG68_RS06110	COG4787	bacterial-type flagellum-dependent cell motility
HGG68_RS06115	COG4786	Flagellar basal body rod
HGG68_RS06125	COG1706	bacterial-type flagellum-dependent cell motility
HGG68_RS06130	COG3951	Flagellar rod assembly protein muramidase FlgJ
HGG68_RS06130	COG1705	Flagellar rod assembly protein muramidase FlgJ
HGG68_RS06135	COG1256	bacterial-type flagellum assembly
HGG68_RS06140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGG68_RS06145	COG1530	ribonuclease E activity
HGG68_RS06150	COG0564	pseudouridine synthase activity
HGG68_RS06155	COG0424	maF-like protein
HGG68_RS06160	COG1399	metal-binding, possibly nucleic acid-binding protein
HGG68_RS06180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HGG68_RS06185	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS06195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HGG68_RS06200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HGG68_RS06205	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HGG68_RS06210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGG68_RS06215	COG0470	DNA polymerase III
HGG68_RS06220	COG0084	hydrolase, TatD family'
HGG68_RS06225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS06225	COG1263	PTS System
HGG68_RS06230	COG4773	Receptor
HGG68_RS06235	COG0537	adenosine 5'-monophosphoramidase activity
HGG68_RS06240	COG5633	Lipoprotein
HGG68_RS06245	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HGG68_RS06250	COG0510	thiamine kinase activity
HGG68_RS06255	COG1472	Belongs to the glycosyl hydrolase 3 family
HGG68_RS06265	COG1252	NADH dehydrogenase
HGG68_RS06270	COG3134	Outer membrane lipoprotein
HGG68_RS06280	COG1309	transcriptional regulator
HGG68_RS06290	COG1376	ErfK ybiS ycfS ynhG family protein
HGG68_RS06290	COG1388	LysM domain
HGG68_RS06295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGG68_RS06300	COG4763	Acyl-transferase
HGG68_RS06305	COG4591	ABC-type transport system involved in lipoprotein release permease component
HGG68_RS06315	COG4591	ABC-type transport system involved in lipoprotein release permease component
HGG68_RS06320	COG1940	carbohydrate kinase activity
HGG68_RS06325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HGG68_RS06330	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HGG68_RS06340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HGG68_RS06345	COG1177	transmembrane transport
HGG68_RS06350	COG0582	viral genome integration into host DNA
HGG68_RS06360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HGG68_RS06435	COG1403	HNH endonuclease
HGG68_RS06440	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HGG68_RS06445	COG0484	heat shock protein binding
HGG68_RS06505	COG3772	lysozyme
HGG68_RS06520	COG3646	Phage regulatory protein
HGG68_RS06525	COG5562	phage envelope protein
HGG68_RS06535	COG4220	transposase activity
HGG68_RS06640	COG5301	cellulose 1,4-beta-cellobiosidase activity
HGG68_RS06660	COG0500	methyltransferase
HGG68_RS06675	COG3842	ATPase activity
HGG68_RS06685	COG2850	peptidyl-arginine hydroxylation
HGG68_RS06780	COG2205	protein histidine kinase activity
HGG68_RS06790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGG68_RS06810	COG1187	pseudouridine synthase activity
HGG68_RS06815	COG0538	isocitrate dehydrogenase activity
HGG68_RS06820	COG0582	viral genome integration into host DNA
HGG68_RS06875	COG1484	DNA-dependent DNA replication
HGG68_RS06880	COG4584	PFAM Integrase catalytic
HGG68_RS07055	COG3772	lysozyme
HGG68_RS07080	COG4220	transposase activity
HGG68_RS07150	COG1196	nuclear chromosome segregation
HGG68_RS07195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HGG68_RS07200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HGG68_RS07205	COG1121	(ABC) transporter
HGG68_RS07220	COG0538	isocitrate dehydrogenase activity
HGG68_RS07230	COG5562	phage envelope protein
HGG68_RS07235	COG0789	Transcriptional regulator
HGG68_RS07240	COG2200	EAL domain
HGG68_RS07320	COG2894	cell division
HGG68_RS07345	COG0179	Fumarylacetoacetate (FAA) hydrolase
HGG68_RS07360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGG68_RS07365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGG68_RS07375	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HGG68_RS07385	COG2719	SpoVR family
HGG68_RS07395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGG68_RS07405	COG1619	proteins homologs of microcin C7 resistance protein MccF
HGG68_RS07415	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HGG68_RS07430	COG0157	Belongs to the NadC ModD family
HGG68_RS07435	COG0500	methyltransferase
HGG68_RS07440	COG1120	ATPase activity
HGG68_RS07445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS07450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HGG68_RS07455	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HGG68_RS07460	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HGG68_RS07460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGG68_RS07460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS07465	COG1461	Dihydroxyacetone kinase
HGG68_RS07470	COG2376	Dihydroxyacetone kinase
HGG68_RS07475	COG3284	Transcriptional regulator
HGG68_RS07485	COG0012	GTP binding
HGG68_RS07500	COG0659	secondary active sulfate transmembrane transporter activity
HGG68_RS07505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGG68_RS07510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGG68_RS07515	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HGG68_RS07530	COG2890	protein-(glutamine-N5) methyltransferase activity
HGG68_RS07535	COG3094	Invasion gene expression up-regulator, SirB
HGG68_RS07540	COG2912	Transglutaminase-like superfamily
HGG68_RS07545	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HGG68_RS07555	COG0387	Pfam Sodium calcium exchanger
HGG68_RS07560	COG4572	Cation transport regulator
HGG68_RS07565	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HGG68_RS07570	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HGG68_RS07575	COG4932	domain protein
HGG68_RS07580	COG2197	response regulator
HGG68_RS07585	COG3850	Histidine kinase
HGG68_RS07590	COG2223	nitrite transmembrane transporter activity
HGG68_RS07595	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGG68_RS07600	COG1140	nitrate reductase beta subunit
HGG68_RS07605	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HGG68_RS07610	COG2181	nitrate reductase activity
HGG68_RS07615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGG68_RS07620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGG68_RS07665	COG0788	formyltetrahydrofolate deformylase activity
HGG68_RS07675	COG1752	Esterase of the alpha-beta hydrolase superfamily
HGG68_RS07680	COG0745	RESPONSE REGULATOR receiver
HGG68_RS07685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HGG68_RS07695	COG1435	thymidine kinase activity
HGG68_RS07705	COG1454	alcohol dehydrogenase
HGG68_RS07705	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS07710	COG2095	MarC family integral membrane protein
HGG68_RS07715	COG4166	transmembrane transport
HGG68_RS07720	COG0601	transmembrane transport
HGG68_RS07725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGG68_RS07730	COG0444	Belongs to the ABC transporter superfamily
HGG68_RS07735	COG4608	Belongs to the ABC transporter superfamily
HGG68_RS07755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HGG68_RS07760	COG2350	Protein conserved in bacteria
HGG68_RS07770	COG1607	acyl-coa hydrolase
HGG68_RS07790	COG3047	cAMP biosynthetic process
HGG68_RS07795	COG3685	Protein conserved in bacteria
HGG68_RS07800	COG3685	Protein conserved in bacteria
HGG68_RS07805	COG0159	tryptophan synthase activity
HGG68_RS07815	COG0135	phosphoribosylanthranilate isomerase activity
HGG68_RS07815	COG0134	indole-3-glycerol-phosphate synthase activity
HGG68_RS07820	COG0512	Glutamine amidotransferase of anthranilate synthase
HGG68_RS07820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGG68_RS07825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGG68_RS07835	COG0613	PHP domain protein
HGG68_RS07840	COG0009	L-threonylcarbamoyladenylate synthase
HGG68_RS07845	COG4907	membrane protein (DUF2207)
HGG68_RS07850	COG1187	pseudouridine synthase activity
HGG68_RS07855	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HGG68_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS07865	COG0616	signal peptide processing
HGG68_RS07880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGG68_RS07885	COG0583	DNA-binding transcription factor activity
HGG68_RS07905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HGG68_RS07915	COG0671	phosphoesterase, PA-phosphatase related
HGG68_RS07920	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HGG68_RS07925	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HGG68_RS07935	COG0023	Translation Initiation Factor
HGG68_RS07945	COG1349	DNA-binding transcription factor activity
HGG68_RS07955	COG5001	Diguanylate cyclase
HGG68_RS07970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGG68_RS07970	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGG68_RS07975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HGG68_RS07985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS07990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGG68_RS08000	COG2814	Major facilitator Superfamily
HGG68_RS08005	COG4172	Belongs to the ABC transporter superfamily
HGG68_RS08010	COG4172	Belongs to the ABC transporter superfamily
HGG68_RS08015	COG4171	peptide transport system, permease
HGG68_RS08020	COG4168	peptide transport system, permease
HGG68_RS08025	COG4166	transmembrane transport
HGG68_RS08040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HGG68_RS08045	COG1842	Phage shock protein A
HGG68_RS08055	COG1983	PspC domain protein
HGG68_RS08065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGG68_RS08070	COG0366	Alpha amylase catalytic
HGG68_RS08075	COG1653	transport
HGG68_RS08080	COG1175	transmembrane transport
HGG68_RS08085	COG0395	ABC-type sugar transport system, permease component
HGG68_RS08090	COG1063	alcohol dehydrogenase
HGG68_RS08095	COG1082	Xylose isomerase domain protein TIM barrel
HGG68_RS08100	COG0673	inositol 2-dehydrogenase activity
HGG68_RS08105	COG1554	hydrolase, family 65, central catalytic
HGG68_RS08110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HGG68_RS08115	COG3842	ATPase activity
HGG68_RS08125	COG1609	Transcriptional regulator
HGG68_RS08130	COG3106	COG3106 Predicted ATPase
HGG68_RS08140	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HGG68_RS08145	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGG68_RS08150	COG4948	Mandelate Racemase Muconate Lactonizing
HGG68_RS08160	COG0702	epimerase
HGG68_RS08170	COG1073	alpha beta
HGG68_RS08175	COG0583	DNA-binding transcription factor activity
HGG68_RS08180	COG4166	transmembrane transport
HGG68_RS08185	COG0668	transmembrane transport
HGG68_RS08190	COG3182	Iron-regulated membrane protein
HGG68_RS08195	COG0589	response to stress
HGG68_RS08200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGG68_RS08205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGG68_RS08215	COG2207	Transcriptional regulator
HGG68_RS08220	COG1566	PFAM secretion protein HlyD family protein
HGG68_RS08230	COG2840	Smr protein MutS2
HGG68_RS08235	COG3706	GGDEF domain
HGG68_RS08245	COG0513	Belongs to the DEAD box helicase family
HGG68_RS08270	COG0589	response to stress
HGG68_RS08275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HGG68_RS08280	COG0674	pyruvate-flavodoxin oxidoreductase activity
HGG68_RS08280	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HGG68_RS08280	COG1013	pyruvate-flavodoxin oxidoreductase activity
HGG68_RS08280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGG68_RS08285	COG3042	response to heat
HGG68_RS08290	COG3187	Heat shock protein
HGG68_RS08295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGG68_RS08300	COG2911	Protein conserved in bacteria
HGG68_RS08310	COG3784	Protein of unknown function (DUF1318)
HGG68_RS08320	COG0667	Aldo Keto reductase
HGG68_RS08325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGG68_RS08330	COG4589	Belongs to the CDS family
HGG68_RS08335	COG2267	carboxylic ester hydrolase activity
HGG68_RS08340	COG2453	phosphatase
HGG68_RS08340	COG0671	phosphoesterase, PA-phosphatase related
HGG68_RS08345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGG68_RS08350	COG1643	Atp-dependent helicase
HGG68_RS08355	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HGG68_RS08360	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS08365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HGG68_RS08370	COG3038	cytochrome b561
HGG68_RS08390	COG0583	DNA-binding transcription factor activity
HGG68_RS08395	COG5383	Protein conserved in bacteria
HGG68_RS08405	COG2841	Protein conserved in bacteria
HGG68_RS08410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGG68_RS08415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGG68_RS08420	COG1275	C4-dicarboxylate transporter malic acid transport protein
HGG68_RS08425	COG0500	methyltransferase
HGG68_RS08435	COG3135	benzoate transporter
HGG68_RS08440	COG1396	sequence-specific DNA binding
HGG68_RS08445	COG0826	peptidase U32
HGG68_RS08460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HGG68_RS08465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HGG68_RS08470	COG3842	ATPase activity
HGG68_RS08475	COG1176	ABC-type spermidine putrescine transport system, permease component I
HGG68_RS08480	COG1177	transmembrane transport
HGG68_RS08505	COG3238	Protein conserved in bacteria
HGG68_RS08510	COG1247	-acetyltransferase
HGG68_RS08525	COG4772	TonB-dependent receptor
HGG68_RS08530	COG3391	amine dehydrogenase activity
HGG68_RS08535	COG1113	amino acid transport
HGG68_RS08540	COG0625	glutathione transferase activity
HGG68_RS08545	COG0625	glutathione transferase activity
HGG68_RS08555	COG3501	Rhs element vgr protein
HGG68_RS08580	COG3501	Rhs element vgr protein
HGG68_RS08610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGG68_RS08615	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HGG68_RS08620	COG0384	phenazine biosynthesis protein PhzF
HGG68_RS08625	COG2181	nitrate reductase activity
HGG68_RS08630	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HGG68_RS08635	COG1140	nitrate reductase beta subunit
HGG68_RS08640	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGG68_RS08645	COG2223	nitrite transmembrane transporter activity
HGG68_RS08650	COG0697	spore germination
HGG68_RS08660	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS08665	COG2864	formate dehydrogenase
HGG68_RS08670	COG3093	addiction module antidote protein HigA
HGG68_RS08680	COG1064	alcohol dehydrogenase
HGG68_RS08685	COG0281	malic enzyme
HGG68_RS08700	COG1764	response to oxidative stress
HGG68_RS08705	COG2202	Pas domain
HGG68_RS08705	COG2200	EAL domain
HGG68_RS08705	COG2199	diguanylate cyclase activity
HGG68_RS08715	COG1649	PFAM Uncharacterised BCR, COG1649
HGG68_RS08720	COG0531	amino acid
HGG68_RS08725	COG0076	glutamate decarboxylase activity
HGG68_RS08730	COG0612	Peptidase, M16
HGG68_RS08735	COG4771	TonB-dependent receptor
HGG68_RS08740	COG4178	(ABC) transporter
HGG68_RS08750	COG0641	radical SAM
HGG68_RS08755	COG3119	arylsulfatase activity
HGG68_RS08760	COG2207	Transcriptional regulator
HGG68_RS08770	COG0243	molybdopterin cofactor binding
HGG68_RS08775	COG3539	Fimbrial protein
HGG68_RS08780	COG3539	Fimbrial protein
HGG68_RS08785	COG3539	Fimbrial protein
HGG68_RS08790	COG3188	usher protein
HGG68_RS08800	COG3539	Fimbrial protein
HGG68_RS08805	COG0702	epimerase
HGG68_RS08815	COG3550	peptidyl-serine autophosphorylation
HGG68_RS08820	COG1396	sequence-specific DNA binding
HGG68_RS08825	COG4106	trans-aconitate 2-methyltransferase activity
HGG68_RS08830	COG3781	membrane
HGG68_RS08840	COG2199	diguanylate cyclase activity
HGG68_RS08850	COG2066	Belongs to the glutaminase family
HGG68_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS08860	COG0583	DNA-binding transcription factor activity
HGG68_RS08880	COG1846	Transcriptional regulator
HGG68_RS08885	COG4977	sequence-specific DNA binding
HGG68_RS08895	COG2723	6-phospho-beta-galactosidase activity
HGG68_RS08905	COG1447	Phosphotransferase system cellobiose-specific component IIA
HGG68_RS08910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HGG68_RS08920	COG2188	Transcriptional regulator
HGG68_RS08925	COG0697	spore germination
HGG68_RS08930	COG2814	Major facilitator Superfamily
HGG68_RS08940	COG3706	GGDEF domain
HGG68_RS08945	COG3111	PFAM Bacterial OB fold (BOF) protein
HGG68_RS08950	COG0339	signal peptide processing
HGG68_RS08955	COG4221	oxidoreductase activity
HGG68_RS08960	COG1802	Transcriptional regulator
HGG68_RS08970	COG0246	Mannitol dehydrogenase
HGG68_RS08975	COG0477	Major facilitator Superfamily
HGG68_RS08980	COG1063	alcohol dehydrogenase
HGG68_RS08985	COG4948	Mandelate Racemase Muconate Lactonizing
HGG68_RS09000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGG68_RS09015	COG0243	molybdopterin cofactor binding
HGG68_RS09020	COG0243	molybdopterin cofactor binding
HGG68_RS09025	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS09030	COG3302	dmso reductase anchor subunit
HGG68_RS09035	COG3381	protein complex oligomerization
HGG68_RS09045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HGG68_RS09050	COG1940	carbohydrate kinase activity
HGG68_RS09055	COG0583	DNA-binding transcription factor activity
HGG68_RS09060	COG2814	Major facilitator Superfamily
HGG68_RS09075	COG3591	Belongs to the peptidase S1B family
HGG68_RS09080	COG2076	Multidrug Resistance protein
HGG68_RS09085	COG2076	Multidrug Resistance protein
HGG68_RS09090	COG0628	permease
HGG68_RS09095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HGG68_RS09100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HGG68_RS09110	COG0531	amino acid
HGG68_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS09120	COG3136	membrane protein required for alginate biosynthesis
HGG68_RS09125	COG0745	RESPONSE REGULATOR receiver
HGG68_RS09130	COG2205	protein histidine kinase activity
HGG68_RS09140	COG0114	fumarate hydratase activity
HGG68_RS09145	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HGG68_RS09145	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HGG68_RS09150	COG1482	cell wall glycoprotein biosynthetic process
HGG68_RS09155	COG5339	Protein conserved in bacteria
HGG68_RS09170	COG3250	beta-galactosidase activity
HGG68_RS09175	COG1309	transcriptional regulator
HGG68_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS09185	COG1609	Transcriptional regulator
HGG68_RS09190	COG1263	PTS System
HGG68_RS09190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS09195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HGG68_RS09205	COG0673	inositol 2-dehydrogenase activity
HGG68_RS09230	COG2878	Part of a membrane complex involved in electron transport
HGG68_RS09240	COG4658	electron transport chain
HGG68_RS09245	COG4659	FMN binding
HGG68_RS09250	COG4660	Part of a membrane complex involved in electron transport
HGG68_RS09255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGG68_RS09260	COG3104	oligopeptide transport
HGG68_RS09265	COG0625	glutathione transferase activity
HGG68_RS09270	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HGG68_RS09285	COG3895	Periplasmic Protein
HGG68_RS09295	COG3133	Outer membrane lipoprotein
HGG68_RS09310	COG1566	PFAM secretion protein HlyD family protein
HGG68_RS09315	COG1289	transmembrane transporter activity
HGG68_RS09320	COG2032	superoxide dismutase activity
HGG68_RS09325	COG4989	oxidoreductase activity
HGG68_RS09330	COG3313	Fe-S protein
HGG68_RS09335	COG1309	transcriptional regulator
HGG68_RS09340	COG1902	pentaerythritol trinitrate reductase activity
HGG68_RS09345	COG0346	lactoylglutathione lyase activity
HGG68_RS09355	COG1201	RNA secondary structure unwinding
HGG68_RS09360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HGG68_RS09365	COG0791	NLP P60 protein
HGG68_RS09370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HGG68_RS09375	COG2814	Major facilitator Superfamily
HGG68_RS09385	COG1609	Transcriptional regulator
HGG68_RS09390	COG0583	DNA-binding transcription factor activity
HGG68_RS09395	COG2814	Major facilitator Superfamily
HGG68_RS09400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HGG68_RS09405	COG0307	riboflavin synthase, alpha
HGG68_RS09415	COG3468	outer membrane autotransporter barrel domain protein
HGG68_RS09435	COG4529	Protein conserved in bacteria
HGG68_RS09445	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HGG68_RS09450	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS09460	COG2414	aldehyde ferredoxin oxidoreductase
HGG68_RS09465	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS09475	COG0469	pyruvate kinase activity
HGG68_RS09480	COG4238	major outer membrane lipoprotein
HGG68_RS09485	COG1376	ErfK ybiS ycfS ynhG family protein
HGG68_RS09500	COG0719	Fe-S assembly protein
HGG68_RS09505	COG0396	ATPase activity
HGG68_RS09510	COG0719	Fe-S assembly protein
HGG68_RS09515	COG0316	Belongs to the HesB IscA family
HGG68_RS09525	COG2050	protein possibly involved in aromatic compounds catabolism
HGG68_RS09530	COG0247	lactate metabolic process
HGG68_RS09530	COG0277	FAD linked oxidase domain protein
HGG68_RS09535	COG0628	permease
HGG68_RS09550	COG0738	Major facilitator superfamily
HGG68_RS09555	COG2271	Major facilitator Superfamily
HGG68_RS09570	COG4670	ketone body catabolic process
HGG68_RS09575	COG1960	acyl-CoA dehydrogenase activity
HGG68_RS09580	COG1917	Cupin 2, conserved barrel domain protein
HGG68_RS09580	COG2207	Transcriptional regulator
HGG68_RS09585	COG2086	electron transfer activity
HGG68_RS09590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HGG68_RS09595	COG0644	oxidoreductase
HGG68_RS09600	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HGG68_RS09605	COG0318	PFAM AMP-dependent synthetase and ligase
HGG68_RS09610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGG68_RS09610	COG0574	Belongs to the PEP-utilizing enzyme family
HGG68_RS09620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HGG68_RS09625	COG4256	Hemin uptake protein
HGG68_RS09635	COG2200	EAL domain
HGG68_RS09640	COG0791	NLP P60 protein
HGG68_RS09650	COG0386	Belongs to the glutathione peroxidase family
HGG68_RS09655	COG4139	cobalamin transport
HGG68_RS09710	COG3137	Salt-induced outer membrane protein
HGG68_RS09715	COG1105	Belongs to the carbohydrate kinase PfkB family
HGG68_RS09725	COG3001	Fructosamine kinase
HGG68_RS09735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HGG68_RS09740	COG1988	membrane-bound metal-dependent
HGG68_RS09745	COG1823	symporter activity
HGG68_RS09755	COG0753	catalase activity
HGG68_RS09760	COG3394	polysaccharide catabolic process
HGG68_RS09765	COG1486	melibiose metabolic process
HGG68_RS09770	COG2169	Transcriptional regulator
HGG68_RS09770	COG1917	Cupin 2, conserved barrel domain protein
HGG68_RS09775	COG1447	Phosphotransferase system cellobiose-specific component IIA
HGG68_RS09780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HGG68_RS09785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HGG68_RS09790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGG68_RS09800	COG0322	excinuclease ABC activity
HGG68_RS09810	COG3678	ATP-independent chaperone mediated protein folding
HGG68_RS09820	COG3724	N-succinylarginine dihydrolase activity
HGG68_RS09825	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS09830	COG3138	arginine N-succinyltransferase
HGG68_RS09840	COG0708	Exodeoxyribonuclease III
HGG68_RS09845	COG0398	Pfam SNARE associated Golgi protein
HGG68_RS09855	COG0398	Pfam SNARE associated Golgi protein
HGG68_RS09860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGG68_RS09865	COG4134	Bacterial extracellular solute-binding protein
HGG68_RS09870	COG4135	transport system, permease component
HGG68_RS09875	COG4136	ATPase activity
HGG68_RS09880	COG2897	thiosulfate sulfurtransferase activity
HGG68_RS09885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGG68_RS09890	COG0494	nUDIX hydrolase
HGG68_RS09900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HGG68_RS09910	COG0443	Heat shock 70 kDa protein
HGG68_RS09920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGG68_RS09925	COG0709	Synthesizes selenophosphate from selenide and ATP
HGG68_RS09930	COG0778	Nitroreductase
HGG68_RS09935	COG0616	signal peptide processing
HGG68_RS09940	COG0252	asparaginase activity
HGG68_RS09945	COG1335	isochorismatase
HGG68_RS09950	COG2814	Major facilitator Superfamily
HGG68_RS09955	COG1349	DNA-binding transcription factor activity
HGG68_RS09960	COG0667	Aldo Keto reductase
HGG68_RS09965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS09970	COG0191	fructose-bisphosphate aldolase activity
HGG68_RS09975	COG1063	alcohol dehydrogenase
HGG68_RS09980	COG2271	Major facilitator Superfamily
HGG68_RS09985	COG1063	alcohol dehydrogenase
HGG68_RS09990	COG3139	Protein of unknown function (DUF1315)
HGG68_RS10000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HGG68_RS10005	COG0676	glucose-6-phosphate 1-epimerase activity
HGG68_RS10010	COG0656	L-ascorbic acid biosynthetic process
HGG68_RS10015	COG3713	MltA-interacting MipA family protein
HGG68_RS10020	COG2766	serine protein kinase
HGG68_RS10030	COG2199	diguanylate cyclase activity
HGG68_RS10035	COG2199	diguanylate cyclase activity
HGG68_RS10040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGG68_RS10055	COG2207	Transcriptional regulator
HGG68_RS10060	COG2807	transmembrane transport
HGG68_RS10065	COG3189	MarR family transcriptional regulator
HGG68_RS10070	COG3042	response to heat
HGG68_RS10075	COG2199	diguanylate cyclase activity
HGG68_RS10075	COG2203	Gaf domain
HGG68_RS10090	COG2261	transglycosylase associated protein
HGG68_RS10100	COG3615	Tellurite resistance protein tehB
HGG68_RS10110	COG0583	DNA-binding transcription factor activity
HGG68_RS10115	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HGG68_RS10120	COG0318	PFAM AMP-dependent synthetase and ligase
HGG68_RS10125	COG3065	identical protein binding
HGG68_RS10130	COG1214	PFAM Peptidase M22, glycoprotease
HGG68_RS10135	COG1199	ATP-dependent helicase activity
HGG68_RS10140	COG0251	oxidation-reduction process
HGG68_RS10155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGG68_RS10160	COG0494	nUDIX hydrolase
HGG68_RS10165	COG1760	l-serine dehydratase
HGG68_RS10170	COG2200	EAL domain
HGG68_RS10175	COG1253	flavin adenine dinucleotide binding
HGG68_RS10180	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS10180	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS10185	COG3715	PTS system
HGG68_RS10190	COG3716	PTS system mannose fructose sorbose family IID component
HGG68_RS10205	COG2226	methyltransferase
HGG68_RS10235	COG1414	Transcriptional regulator
HGG68_RS10240	COG2814	Major facilitator Superfamily
HGG68_RS10250	COG0793	Belongs to the peptidase S41A family
HGG68_RS10260	COG1956	GAF domain-containing protein
HGG68_RS10265	COG2995	paraquat-inducible protein a
HGG68_RS10270	COG3008	intermembrane lipid transfer
HGG68_RS10275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGG68_RS10275	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HGG68_RS10290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HGG68_RS10300	COG1276	copper resistance
HGG68_RS10305	COG2372	response to copper ion
HGG68_RS10315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HGG68_RS10320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HGG68_RS10330	COG2979	Protein of unknown function (DUF533)
HGG68_RS10340	COG3141	response to X-ray
HGG68_RS10350	COG0800	Aldolase
HGG68_RS10355	COG0129	dihydroxy-acid dehydratase activity
HGG68_RS10360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGG68_RS10365	COG1737	Transcriptional regulator
HGG68_RS10370	COG0469	pyruvate kinase activity
HGG68_RS10375	COG1560	Kdo2-lipid A biosynthetic process
HGG68_RS10380	COG0739	heme binding
HGG68_RS10385	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HGG68_RS10395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HGG68_RS10425	COG0217	transcriptional regulatory protein
HGG68_RS10430	COG0494	nUDIX hydrolase
HGG68_RS10440	COG1335	isochorismatase
HGG68_RS10445	COG1801	Protein of unknown function DUF72
HGG68_RS10450	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HGG68_RS10465	COG0243	molybdopterin cofactor binding
HGG68_RS10470	COG3005	denitrification pathway
HGG68_RS10480	COG3102	Protein conserved in bacteria
HGG68_RS10495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGG68_RS10505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HGG68_RS10510	COG0745	RESPONSE REGULATOR receiver
HGG68_RS10520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HGG68_RS10530	COG0840	transmembrane signaling receptor activity
HGG68_RS10535	COG0835	chemotaxis
HGG68_RS10540	COG2198	Histidine kinase
HGG68_RS10540	COG0643	Histidine kinase
HGG68_RS10545	COG1360	Flagellar Motor Protein
HGG68_RS10550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HGG68_RS10565	COG0589	response to stress
HGG68_RS10575	COG1877	trehalose-phosphatase activity
HGG68_RS10580	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS10585	COG1129	ABC transporter
HGG68_RS10590	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS10595	COG1528	Iron-storage protein
HGG68_RS10615	COG1528	Iron-storage protein
HGG68_RS10625	COG0814	amino acid
HGG68_RS10630	COG3318	Belongs to the UPF0149 family
HGG68_RS10630	COG3012	SEC-C Motif Domain Protein
HGG68_RS10660	COG2197	response regulator
HGG68_RS10675	COG2197	response regulator
HGG68_RS10680	COG1126	abc transporter atp-binding protein
HGG68_RS10685	COG0765	amino acid transport
HGG68_RS10690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HGG68_RS10700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS10710	COG1191	sigma factor activity
HGG68_RS10720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HGG68_RS10725	COG1516	flagellar protein fliS
HGG68_RS10735	COG0366	Alpha amylase catalytic
HGG68_RS10745	COG2391	methyltransferase activity
HGG68_RS10750	COG0425	Belongs to the sulfur carrier protein TusA family
HGG68_RS10755	COG2135	peptidase activity
HGG68_RS10770	COG2207	Transcriptional regulator
HGG68_RS10775	COG1881	PFAM PEBP family protein
HGG68_RS10780	COG2076	Multidrug Resistance protein
HGG68_RS10790	COG1766	The M ring may be actively involved in energy transduction
HGG68_RS10795	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HGG68_RS10800	COG1317	bacterial-type flagellum organization
HGG68_RS10805	COG1157	protein secretion by the type III secretion system
HGG68_RS10810	COG2882	bacterial-type flagellum organization
HGG68_RS10815	COG3144	bacterial-type flagellum assembly
HGG68_RS10820	COG1580	Controls the rotational direction of flagella during chemotaxis
HGG68_RS10825	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HGG68_RS10830	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HGG68_RS10835	COG3190	flagellar
HGG68_RS10840	COG1338	Plays a role in the flagellum-specific transport system
HGG68_RS10845	COG1987	bacterial-type flagellum assembly
HGG68_RS10850	COG1684	flagellar biosynthetic protein fliR
HGG68_RS10855	COG2197	response regulator
HGG68_RS10870	COG3769	mannosylglycerate metabolic process
HGG68_RS10875	COG3706	GGDEF domain
HGG68_RS10880	COG5475	Uncharacterized small protein (DUF2158)
HGG68_RS10885	COG2354	Protein conserved in bacteria
HGG68_RS10890	COG0697	spore germination
HGG68_RS10895	COG3727	T/G mismatch-specific endonuclease activity
HGG68_RS10900	COG0270	DNA (cytosine-5-)-methyltransferase activity
HGG68_RS10905	COG1418	mRNA catabolic process
HGG68_RS10915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HGG68_RS10925	COG2205	protein histidine kinase activity
HGG68_RS10930	COG0745	RESPONSE REGULATOR receiver
HGG68_RS10935	COG2351	hydroxyisourate hydrolase activity
HGG68_RS10940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGG68_RS10945	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HGG68_RS10950	COG3443	Belongs to the bacterial solute-binding protein 9 family
HGG68_RS10955	COG0582	viral genome integration into host DNA
HGG68_RS10985	COG4916	TIR domain
HGG68_RS11095	COG0582	viral genome integration into host DNA
HGG68_RS11105	COG2814	Major facilitator Superfamily
HGG68_RS11110	COG1132	(ABC) transporter
HGG68_RS11155	COG1021	2,3-dihydroxybenzoate-AMP ligase
HGG68_RS11160	COG4771	TonB-dependent receptor
HGG68_RS11165	COG4932	domain protein
HGG68_RS11165	COG2373	Large extracellular alpha-helical protein
HGG68_RS11165	COG1388	LysM domain
HGG68_RS11175	COG1470	cell adhesion involved in biofilm formation
HGG68_RS11175	COG1388	LysM domain
HGG68_RS11185	COG0477	Major facilitator Superfamily
HGG68_RS11190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGG68_RS11195	COG0217	transcriptional regulatory protein
HGG68_RS11205	COG0583	DNA-binding transcription factor activity
HGG68_RS11210	COG0583	DNA-binding transcription factor activity
HGG68_RS11220	COG0534	Mate efflux family protein
HGG68_RS11230	COG0582	viral genome integration into host DNA
HGG68_RS11240	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HGG68_RS11265	COG0154	amidase activity
HGG68_RS11295	COG1960	acyl-CoA dehydrogenase activity
HGG68_RS11300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGG68_RS11305	COG1250	3-hydroxyacyl-CoA dehydrogenase
HGG68_RS11320	COG2197	response regulator
HGG68_RS11340	COG1376	ErfK ybiS ycfS ynhG family protein
HGG68_RS11355	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HGG68_RS11360	COG4771	TonB-dependent receptor
HGG68_RS11365	COG1475	DNA binding
HGG68_RS11370	COG3969	phosphoadenosine phosphosulfate
HGG68_RS11375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HGG68_RS11380	COG1215	transferase activity, transferring glycosyl groups
HGG68_RS11400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS11415	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HGG68_RS11450	COG3547	Transposase (IS116 IS110 IS902 family)
HGG68_RS11465	COG4584	PFAM Integrase catalytic
HGG68_RS11470	COG1484	DNA-dependent DNA replication
HGG68_RS11520	COG1120	ATPase activity
HGG68_RS11525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS11580	COG2003	Belongs to the UPF0758 family
HGG68_RS11610	COG4372	Transposase
HGG68_RS11625	COG1289	transmembrane transporter activity
HGG68_RS11635	COG1686	Belongs to the peptidase S11 family
HGG68_RS11640	COG2925	Exonuclease
HGG68_RS11645	COG0531	amino acid
HGG68_RS11655	COG0583	DNA-binding transcription factor activity
HGG68_RS11660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGG68_RS11665	COG4115	mRNA cleavage
HGG68_RS11670	COG2161	toxin-antitoxin pair type II binding
HGG68_RS11685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGG68_RS11695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HGG68_RS11695	COG0131	Imidazoleglycerol-phosphate dehydratase
HGG68_RS11700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGG68_RS11715	COG0140	phosphoribosyl-ATP diphosphatase activity
HGG68_RS11715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HGG68_RS11720	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HGG68_RS11725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGG68_RS11730	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGG68_RS11735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGG68_RS11750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HGG68_RS11765	COG1216	Glycosyl transferase, family 2
HGG68_RS11780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HGG68_RS11790	COG0438	transferase activity, transferring glycosyl groups
HGG68_RS11795	COG2327	Polysaccharide pyruvyl transferase
HGG68_RS11800	COG2244	polysaccharide biosynthetic process
HGG68_RS11805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGG68_RS11810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGG68_RS11815	COG0662	Cupin 2, conserved barrel domain protein
HGG68_RS11815	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HGG68_RS11820	COG0297	glycogen (starch) synthase activity
HGG68_RS11825	COG1051	belongs to the nudix hydrolase family
HGG68_RS11830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGG68_RS11835	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HGG68_RS11840	COG0110	maltose O-acetyltransferase activity
HGG68_RS11845	COG1216	Glycosyl transferase, family 2
HGG68_RS11855	COG0438	transferase activity, transferring glycosyl groups
HGG68_RS11860	COG1045	serine acetyltransferase
HGG68_RS11865	COG0463	Glycosyl transferase, family 2
HGG68_RS11870	COG0489	protein tyrosine kinase activity
HGG68_RS11870	COG3206	protein involved in exopolysaccharide biosynthesis
HGG68_RS11875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGG68_RS11880	COG1596	polysaccharide export
HGG68_RS11890	COG1253	flavin adenine dinucleotide binding
HGG68_RS11895	COG2982	Protein involved in outer membrane biogenesis
HGG68_RS11905	COG0572	uridine kinase
HGG68_RS11910	COG5001	Diguanylate cyclase
HGG68_RS11910	COG5002	protein histidine kinase activity
HGG68_RS11910	COG3447	MASE1 domain protein
HGG68_RS11915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGG68_RS11920	COG0443	Heat shock 70 kDa protein
HGG68_RS11925	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HGG68_RS11930	COG0631	protein serine/threonine phosphatase activity
HGG68_RS11935	COG4245	von Willebrand factor, type A
HGG68_RS11950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS11960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGG68_RS11965	COG2814	Major facilitator Superfamily
HGG68_RS11970	COG2205	protein histidine kinase activity
HGG68_RS11975	COG0745	RESPONSE REGULATOR receiver
HGG68_RS11980	COG3422	double-strand break repair
HGG68_RS12005	COG0826	peptidase U32
HGG68_RS12015	COG1597	lipid kinase activity
HGG68_RS12025	COG1063	alcohol dehydrogenase
HGG68_RS12030	COG3775	system Galactitol-specific IIC component
HGG68_RS12035	COG3414	Phosphotransferase system galactitol-specific IIB component
HGG68_RS12040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS12050	COG0191	fructose-bisphosphate aldolase activity
HGG68_RS12060	COG1830	Aldolase
HGG68_RS12065	COG2211	Major facilitator Superfamily
HGG68_RS12070	COG1397	ADP-ribosylglycohydrolase
HGG68_RS12075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS12080	COG2188	Transcriptional regulator
HGG68_RS12085	COG3757	hydrolase, family 25
HGG68_RS12090	COG0351	phosphomethylpyrimidine kinase
HGG68_RS12095	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGG68_RS12110	COG5455	response to cobalt ion
HGG68_RS12115	COG3539	Fimbrial protein
HGG68_RS12120	COG3188	usher protein
HGG68_RS12125	COG3121	Chaperone
HGG68_RS12130	COG3539	Fimbrial protein
HGG68_RS12145	COG0489	protein tyrosine kinase activity
HGG68_RS12155	COG3831	ATPase activity
HGG68_RS12160	COG3831	ATPase activity
HGG68_RS12170	COG0714	Associated with various cellular activities
HGG68_RS12175	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HGG68_RS12180	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HGG68_RS12185	COG4715	Zinc finger, swim domain protein
HGG68_RS12190	COG4808	Protein conserved in bacteria
HGG68_RS12195	COG4807	Protein conserved in bacteria
HGG68_RS12200	COG3279	Response regulator of the LytR AlgR family
HGG68_RS12205	COG3275	phosphorelay sensor kinase activity
HGG68_RS12210	COG0789	Transcriptional regulator
HGG68_RS12220	COG1174	glycine betaine transport
HGG68_RS12225	COG1125	glycine betaine transport
HGG68_RS12230	COG1174	glycine betaine transport
HGG68_RS12235	COG1732	Glycine betaine
HGG68_RS12240	COG1472	Belongs to the glycosyl hydrolase 3 family
HGG68_RS12245	COG0277	FAD linked oxidase domain protein
HGG68_RS12250	COG1686	Belongs to the peptidase S11 family
HGG68_RS12260	COG0586	Pfam SNARE associated Golgi protein
HGG68_RS12270	COG1538	Outer membrane efflux protein
HGG68_RS12280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGG68_RS12290	COG1346	cytolysis
HGG68_RS12300	COG2949	membrane
HGG68_RS12310	COG0493	'glutamate synthase
HGG68_RS12315	COG0167	dihydroorotate dehydrogenase activity
HGG68_RS12315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HGG68_RS12320	COG4211	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS12330	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS12335	COG1609	Transcriptional regulator
HGG68_RS12340	COG2311	Membrane
HGG68_RS12355	COG4771	TonB-dependent receptor
HGG68_RS12360	COG0833	amino acid
HGG68_RS12365	COG0583	DNA-binding transcription factor activity
HGG68_RS12370	COG2855	membrane
HGG68_RS12380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS12380	COG1522	sequence-specific DNA binding
HGG68_RS12390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGG68_RS12395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGG68_RS12400	COG2313	pseudouridylate synthase activity
HGG68_RS12405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS12410	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HGG68_RS12410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS12410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS12415	COG1105	Belongs to the carbohydrate kinase PfkB family
HGG68_RS12420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS12420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS12425	COG2814	Major facilitator Superfamily
HGG68_RS12440	COG0246	Mannitol dehydrogenase
HGG68_RS12445	COG0523	cobalamin synthesis protein
HGG68_RS12450	COG0671	phosphoesterase, PA-phosphatase related
HGG68_RS12455	COG0791	NLP P60 protein
HGG68_RS12460	COG2200	EAL domain
HGG68_RS12465	COG4166	transmembrane transport
HGG68_RS12470	COG4174	ABC transporter (Permease)
HGG68_RS12475	COG4239	(ABC) transporter, permease
HGG68_RS12480	COG4172	Belongs to the ABC transporter superfamily
HGG68_RS12490	COG2814	Major facilitator Superfamily
HGG68_RS12495	COG1187	pseudouridine synthase activity
HGG68_RS12500	COG1061	Type III restriction enzyme res subunit
HGG68_RS12520	COG3083	sulfuric ester hydrolase activity
HGG68_RS12535	COG2197	response regulator
HGG68_RS12540	COG3088	subunit of a heme lyase
HGG68_RS12540	COG4235	cytochrome complex assembly
HGG68_RS12545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HGG68_RS12550	COG1138	Cytochrome C-type biogenesis protein
HGG68_RS12560	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HGG68_RS12565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HGG68_RS12570	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HGG68_RS12575	COG4133	protoheme IX ABC transporter activity
HGG68_RS12580	COG3005	denitrification pathway
HGG68_RS12585	COG3043	anaerobic respiration
HGG68_RS12590	COG0348	domain, Protein
HGG68_RS12595	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS12605	COG3062	negative regulation of establishment of protein localization
HGG68_RS12610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS12610	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS12620	COG0579	oxidoreductase
HGG68_RS12625	COG4615	Cyclic peptide transporter
HGG68_RS12630	COG3145	DNA-N1-methyladenine dioxygenase activity
HGG68_RS12635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGG68_RS12635	COG2169	Transcriptional regulator
HGG68_RS12640	COG1477	protein flavinylation
HGG68_RS12645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HGG68_RS12650	COG0642	Histidine kinase
HGG68_RS12650	COG2198	Histidine kinase
HGG68_RS12655	COG2197	response regulator
HGG68_RS12660	COG0784	Response regulator, receiver
HGG68_RS12660	COG2205	protein histidine kinase activity
HGG68_RS12665	COG3852	Histidine kinase
HGG68_RS12670	COG2204	response regulator
HGG68_RS12675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGG68_RS12680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HGG68_RS12690	COG0183	Belongs to the thiolase family
HGG68_RS12695	COG4676	Protein conserved in bacteria
HGG68_RS12700	COG5445	Predicted secreted protein (DUF2300)
HGG68_RS12705	COG2373	Large extracellular alpha-helical protein
HGG68_RS12710	COG3234	Protein of unknown function (DUF1175)
HGG68_RS12715	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HGG68_RS12720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGG68_RS12725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGG68_RS12735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGG68_RS12740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGG68_RS12745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGG68_RS12750	COG3642	lipopolysaccharide core region biosynthetic process
HGG68_RS12755	COG0584	glycerophosphoryl diester phosphodiesterase
HGG68_RS12760	COG2271	Major facilitator Superfamily
HGG68_RS12765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HGG68_RS12770	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HGG68_RS12775	COG0247	lactate metabolic process
HGG68_RS12780	COG5464	transposase or invertase
HGG68_RS12790	COG2271	Major facilitator Superfamily
HGG68_RS12795	COG4948	Mandelate Racemase Muconate Lactonizing
HGG68_RS12800	COG1414	Transcriptional regulator
HGG68_RS12835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGG68_RS12835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGG68_RS12845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGG68_RS12865	COG0318	PFAM AMP-dependent synthetase and ligase
HGG68_RS12870	COG1441	menaquinone biosynthetic process
HGG68_RS12875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGG68_RS12890	COG1169	isochorismate synthase
HGG68_RS12895	COG4575	ribosome binding
HGG68_RS12900	COG2153	protein acetylation
HGG68_RS12910	COG2304	oxidoreductase activity
HGG68_RS12915	COG2234	aminopeptidase activity
HGG68_RS12930	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGG68_RS12935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HGG68_RS12945	COG0839	Belongs to the complex I subunit 6 family
HGG68_RS12960	COG1034	ATP synthesis coupled electron transport
HGG68_RS12965	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HGG68_RS12970	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HGG68_RS12990	COG0583	DNA-binding transcription factor activity
HGG68_RS12995	COG0436	Aminotransferase
HGG68_RS13005	COG0490	domain, Protein
HGG68_RS13005	COG0471	metal ion transport
HGG68_RS13010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HGG68_RS13020	COG3092	negative regulation of chromosome organization
HGG68_RS13025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGG68_RS13030	COG0857	belongs to the CobB CobQ family
HGG68_RS13030	COG0280	phosphate acetyltransferase
HGG68_RS13035	COG1288	antiporter activity
HGG68_RS13040	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HGG68_RS13045	COG0622	Phosphoesterase
HGG68_RS13050	COG0625	glutathione transferase activity
HGG68_RS13055	COG0625	glutathione transferase activity
HGG68_RS13060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGG68_RS13065	COG1090	epimerase
HGG68_RS13070	COG4598	ABC transporter
HGG68_RS13075	COG4160	amino acid transport
HGG68_RS13080	COG4215	(ABC) transporter
HGG68_RS13085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS13095	COG0163	prenyltransferase activity
HGG68_RS13100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGG68_RS13105	COG1286	toxin biosynthetic process
HGG68_RS13110	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HGG68_RS13115	COG0285	dihydrofolate synthase activity
HGG68_RS13120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGG68_RS13125	COG0586	Pfam SNARE associated Golgi protein
HGG68_RS13135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGG68_RS13150	COG2814	Major facilitator Superfamily
HGG68_RS13155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HGG68_RS13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HGG68_RS13160	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HGG68_RS13170	COG3101	peptidyl-lysine hydroxylation
HGG68_RS13175	COG0730	response to heat
HGG68_RS13205	COG3539	Fimbrial protein
HGG68_RS13210	COG3539	Fimbrial protein
HGG68_RS13215	COG3539	Fimbrial protein
HGG68_RS13220	COG3121	Chaperone
HGG68_RS13225	COG3188	usher protein
HGG68_RS13230	COG3539	Fimbrial protein
HGG68_RS13235	COG2062	phosphohistidine phosphatase, SixA
HGG68_RS13240	COG1250	3-hydroxyacyl-CoA dehydrogenase
HGG68_RS13240	COG1024	Enoyl-CoA hydratase
HGG68_RS13245	COG0183	Belongs to the thiolase family
HGG68_RS13250	COG3691	Protein conserved in bacteria
HGG68_RS13255	COG2067	long-chain fatty acid transport protein
HGG68_RS13265	COG2116	formate transmembrane transporter activity
HGG68_RS13290	COG0582	viral genome integration into host DNA
HGG68_RS13295	COG0582	viral genome integration into host DNA
HGG68_RS13300	COG0583	DNA-binding transcription factor activity
HGG68_RS13305	COG2610	gluconate transmembrane transporter activity
HGG68_RS13310	COG3048	D-serine ammonia-lyase activity
HGG68_RS13315	COG0477	Major facilitator Superfamily
HGG68_RS13320	COG1566	PFAM secretion protein HlyD family protein
HGG68_RS13325	COG2197	response regulator
HGG68_RS13330	COG2205	protein histidine kinase activity
HGG68_RS13330	COG0784	Response regulator, receiver
HGG68_RS13330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS13330	COG2198	Histidine kinase
HGG68_RS13335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HGG68_RS13340	COG0679	Auxin Efflux Carrier
HGG68_RS13345	COG0028	Belongs to the TPP enzyme family
HGG68_RS13350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HGG68_RS13370	COG1560	Kdo2-lipid A biosynthetic process
HGG68_RS13380	COG0436	Aminotransferase
HGG68_RS13385	COG3275	phosphorelay sensor kinase activity
HGG68_RS13390	COG3279	Response regulator of the LytR AlgR family
HGG68_RS13395	COG2207	Transcriptional regulator
HGG68_RS13400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS13400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS13400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGG68_RS13405	COG1363	Peptidase, m42
HGG68_RS13410	COG0006	proline dipeptidase activity
HGG68_RS13415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS13420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS13430	COG0038	chloride channel
HGG68_RS13445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGG68_RS13450	COG2200	EAL domain
HGG68_RS13450	COG2199	diguanylate cyclase activity
HGG68_RS13465	COG3415	Transposase
HGG68_RS13470	COG3415	Transposase
HGG68_RS13475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGG68_RS13500	COG0583	DNA-binding transcription factor activity
HGG68_RS13510	COG2211	Major facilitator Superfamily
HGG68_RS13515	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HGG68_RS13525	COG0583	DNA-binding transcription factor activity
HGG68_RS13530	COG0385	Bile acid
HGG68_RS13535	COG3530	Putative quorum-sensing-regulated virulence factor
HGG68_RS13545	COG3115	cell septum assembly
HGG68_RS13555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HGG68_RS13560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS13565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGG68_RS13570	COG2190	(PTS) system
HGG68_RS13585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HGG68_RS13590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HGG68_RS13595	COG4208	sulfate ABC transporter
HGG68_RS13600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HGG68_RS13605	COG4150	thiosulfate binding
HGG68_RS13610	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS13620	COG1263	PTS System
HGG68_RS13620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS13625	COG2837	iron assimilation
HGG68_RS13645	COG0860	N-Acetylmuramoyl-L-alanine amidase
HGG68_RS13655	COG2207	Transcriptional regulator
HGG68_RS13660	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGG68_RS13665	COG4816	utilization protein
HGG68_RS13675	COG4303	Ethanolamine ammonia lyase large subunit
HGG68_RS13680	COG4819	ethanolamine utilization protein
HGG68_RS13685	COG3192	ethanolamine utilization protein
HGG68_RS13690	COG1454	alcohol dehydrogenase
HGG68_RS13695	COG4820	ethanolamine utilization protein (EutJ)
HGG68_RS13700	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS13705	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HGG68_RS13710	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGG68_RS13715	COG0280	phosphate acetyltransferase
HGG68_RS13720	COG4812	Cobalamin adenosyltransferase
HGG68_RS13725	COG4766	ethanolamine catabolic process
HGG68_RS13730	COG4917	ethanolamine utilization protein
HGG68_RS13735	COG4810	utilization protein
HGG68_RS13740	COG0281	malic enzyme
HGG68_RS13740	COG0280	phosphate acetyltransferase
HGG68_RS13745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGG68_RS13750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGG68_RS13755	COG5342	invasion associated locus B
HGG68_RS13765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS13765	COG0493	'glutamate synthase
HGG68_RS13770	COG3850	Histidine kinase
HGG68_RS13775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGG68_RS13785	COG1393	Belongs to the ArsC family
HGG68_RS13800	COG0400	carboxylic ester hydrolase activity
HGG68_RS13810	COG2321	neutral zinc metallopeptidase
HGG68_RS13820	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HGG68_RS13830	COG2716	regulation of RNA biosynthetic process
HGG68_RS13835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGG68_RS13840	COG0628	permease
HGG68_RS13845	COG4783	chaperone-mediated protein folding
HGG68_RS13850	COG1393	Belongs to the ArsC family
HGG68_RS13860	COG2233	PERMEase
HGG68_RS13875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGG68_RS13880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGG68_RS13885	COG0248	Ppx GppA phosphatase
HGG68_RS13890	COG2200	EAL domain
HGG68_RS13905	COG3133	Outer membrane lipoprotein
HGG68_RS13920	COG0517	IMP dehydrogenase activity
HGG68_RS13920	COG0516	GMP reductase activity
HGG68_RS13925	COG1570	exodeoxyribonuclease VII activity
HGG68_RS13945	COG1645	bacterial-type flagellum-dependent swarming motility
HGG68_RS13960	COG2976	Protein conserved in bacteria
HGG68_RS13975	COG1426	Protein conserved in bacteria
HGG68_RS13980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HGG68_RS13990	COG4953	penicillin-binding protein 1C
HGG68_RS13995	COG2373	Large extracellular alpha-helical protein
HGG68_RS14000	COG2897	thiosulfate sulfurtransferase activity
HGG68_RS14015	COG2975	iron-sulfur cluster assembly
HGG68_RS14020	COG0633	Ferredoxin
HGG68_RS14025	COG0443	Heat shock 70 kDa protein
HGG68_RS14040	COG0822	iron-sulfur transferase activity
HGG68_RS14060	COG0483	inositol monophosphate 1-phosphatase activity
HGG68_RS14065	COG1073	alpha beta
HGG68_RS14070	COG3711	transcriptional antiterminator
HGG68_RS14075	COG2814	Major facilitator Superfamily
HGG68_RS14080	COG2259	Doxx family
HGG68_RS14085	COG2017	converts alpha-aldose to the beta-anomer
HGG68_RS14090	COG1063	alcohol dehydrogenase
HGG68_RS14095	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS14100	COG1129	ABC transporter
HGG68_RS14105	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS14110	COG0457	Tetratricopeptide repeat
HGG68_RS14115	COG1940	carbohydrate kinase activity
HGG68_RS14125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGG68_RS14125	COG1017	nitric oxide dioxygenase activity
HGG68_RS14130	COG0347	Belongs to the P(II) protein family
HGG68_RS14135	COG2204	response regulator
HGG68_RS14140	COG3170	Tfp pilus assembly protein FimV
HGG68_RS14145	COG2205	protein histidine kinase activity
HGG68_RS14150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGG68_RS14150	COG0047	phosphoribosylformylglycinamidine synthase activity
HGG68_RS14155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HGG68_RS14160	COG0590	tRNA wobble adenosine to inosine editing
HGG68_RS14165	COG0560	Phosphoserine phosphatase
HGG68_RS14170	COG1737	Transcriptional regulator
HGG68_RS14175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS14190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HGG68_RS14210	COG0681	Belongs to the peptidase S26 family
HGG68_RS14220	COG3086	response to oxidative stress
HGG68_RS14225	COG3026	antisigma factor binding
HGG68_RS14230	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HGG68_RS14235	COG1595	DNA-templated transcription, initiation
HGG68_RS14245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HGG68_RS14255	COG0513	Belongs to the DEAD box helicase family
HGG68_RS14260	COG0583	DNA-binding transcription factor activity
HGG68_RS14280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGG68_RS14285	COG3118	belongs to the thioredoxin family
HGG68_RS14290	COG3148	PFAM DTW domain containing protein
HGG68_RS14295	COG1042	CoA-binding domain protein
HGG68_RS14295	COG0045	succinate-CoA ligase (ADP-forming) activity
HGG68_RS14295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGG68_RS14300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGG68_RS14305	COG5544	Lipoprotein
HGG68_RS14310	COG0477	Major facilitator Superfamily
HGG68_RS14335	COG0542	response to heat
HGG68_RS14345	COG0564	pseudouridine synthase activity
HGG68_RS14350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGG68_RS14355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGG68_RS14365	COG0077	Prephenate dehydratase
HGG68_RS14365	COG1605	Chorismate mutase
HGG68_RS14370	COG1605	Chorismate mutase
HGG68_RS14370	COG0287	Prephenate dehydrogenase
HGG68_RS14375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HGG68_RS14390	COG2199	diguanylate cyclase activity
HGG68_RS14395	COG2885	chlorophyll binding
HGG68_RS14420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGG68_RS14425	COG4137	Cytochrome C assembly protein
HGG68_RS14430	COG4536	flavin adenine dinucleotide binding
HGG68_RS14445	COG0497	DNA recombination
HGG68_RS14450	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGG68_RS14460	COG2867	negative regulation of translational initiation
HGG68_RS14495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HGG68_RS14520	COG5301	cellulose 1,4-beta-cellobiosidase activity
HGG68_RS14560	COG1196	nuclear chromosome segregation
HGG68_RS14610	COG1030	water channel activity
HGG68_RS14630	COG4220	transposase activity
HGG68_RS14660	COG1278	Cold shock
HGG68_RS14670	COG3772	lysozyme
HGG68_RS14690	COG1278	Cold shock
HGG68_RS14695	COG1278	Cold shock
HGG68_RS14705	COG0484	heat shock protein binding
HGG68_RS14710	COG1403	HNH endonuclease
HGG68_RS14720	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HGG68_RS14735	COG1846	Transcriptional regulator
HGG68_RS14775	COG5532	Uncharacterized conserved protein (DUF2303)
HGG68_RS14780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HGG68_RS14795	COG0582	viral genome integration into host DNA
HGG68_RS14815	COG0579	oxidoreductase
HGG68_RS14820	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS14825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGG68_RS14830	COG1113	amino acid transport
HGG68_RS14835	COG1802	Transcriptional regulator
HGG68_RS14840	COG1652	LysM domain
HGG68_RS14845	COG0401	homolog of Blt101
HGG68_RS14850	COG0640	Transcriptional regulator
HGG68_RS14855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGG68_RS14860	COG2916	Histone family protein nucleoid-structuring protein H-NS
HGG68_RS14875	COG4575	ribosome binding
HGG68_RS14880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HGG68_RS14885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGG68_RS14890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HGG68_RS14900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGG68_RS14905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGG68_RS14910	COG4175	Glycine betaine
HGG68_RS14915	COG4176	ABC-type proline glycine betaine transport system permease component
HGG68_RS14920	COG2113	Glycine betaine
HGG68_RS14925	COG2814	Major facilitator Superfamily
HGG68_RS14930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HGG68_RS14940	COG1846	Transcriptional regulator
HGG68_RS14945	COG1566	PFAM secretion protein HlyD family protein
HGG68_RS14950	COG2814	Major facilitator Superfamily
HGG68_RS14975	COG1238	metal cluster binding
HGG68_RS14980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HGG68_RS15015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HGG68_RS15035	COG1546	Belongs to the CinA family
HGG68_RS15040	COG2951	lytic endotransglycosylase activity
HGG68_RS15045	COG3730	PTS system glucitol sorbitol-specific
HGG68_RS15050	COG3732	PTS system glucitol sorbitol-specific
HGG68_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS15065	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS15070	COG1349	DNA-binding transcription factor activity
HGG68_RS15075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HGG68_RS15075	COG0517	IMP dehydrogenase activity
HGG68_RS15080	COG3604	Transcriptional regulator
HGG68_RS15090	COG0446	pyridine nucleotide-disulphide oxidoreductase
HGG68_RS15095	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HGG68_RS15100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS15110	COG5499	transcription regulator containing HTH domain
HGG68_RS15115	COG4680	protein conserved in bacteria
HGG68_RS15125	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HGG68_RS15135	COG3260	NADH ubiquinone oxidoreductase 20
HGG68_RS15140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGG68_RS15145	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HGG68_RS15145	COG3261	NADH dehydrogenase
HGG68_RS15150	COG0650	Formate hydrogenlyase subunit 4
HGG68_RS15155	COG0651	ATP synthesis coupled electron transport
HGG68_RS15160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS15170	COG0375	protein maturation
HGG68_RS15175	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HGG68_RS15180	COG0298	carbon dioxide binding
HGG68_RS15185	COG0409	Hydrogenase expression formation protein
HGG68_RS15190	COG0309	Hydrogenase expression formation protein (HypE)
HGG68_RS15195	COG3604	Transcriptional regulator
HGG68_RS15210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGG68_RS15215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HGG68_RS15220	COG1349	DNA-binding transcription factor activity
HGG68_RS15225	COG2084	Dehydrogenase
HGG68_RS15230	COG3395	kinase activity
HGG68_RS15235	COG0235	Class ii aldolase
HGG68_RS15240	COG3622	Belongs to the hyi family
HGG68_RS15245	COG2610	gluconate transmembrane transporter activity
HGG68_RS15265	COG4942	peptidase
HGG68_RS15265	COG1388	LysM domain
HGG68_RS15280	COG0585	pseudouridine synthase activity
HGG68_RS15320	COG2234	aminopeptidase activity
HGG68_RS15335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGG68_RS15340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HGG68_RS15345	COG0720	synthase
HGG68_RS15350	COG0644	oxidoreductase
HGG68_RS15355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HGG68_RS15360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HGG68_RS15365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HGG68_RS15370	COG2086	electron transfer activity
HGG68_RS15375	COG0477	Major facilitator Superfamily
HGG68_RS15380	COG0277	FAD linked oxidase domain protein
HGG68_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS15390	COG2223	nitrite transmembrane transporter activity
HGG68_RS15395	COG1070	Carbohydrate kinase
HGG68_RS15400	COG0602	queuosine metabolic process
HGG68_RS15410	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HGG68_RS15420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HGG68_RS15435	COG3956	TIGRFAM MazG family protein
HGG68_RS15440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGG68_RS15450	COG4999	Histidine kinase
HGG68_RS15450	COG3850	Histidine kinase
HGG68_RS15450	COG3437	response regulator, receiver
HGG68_RS15450	COG2205	protein histidine kinase activity
HGG68_RS15455	COG4948	Mandelate Racemase Muconate Lactonizing
HGG68_RS15460	COG4948	Mandelate Racemase Muconate Lactonizing
HGG68_RS15465	COG2271	Major facilitator Superfamily
HGG68_RS15470	COG0716	FMN binding
HGG68_RS15475	COG0564	pseudouridine synthase activity
HGG68_RS15480	COG3098	single-species biofilm formation
HGG68_RS15495	COG1611	Belongs to the LOG family
HGG68_RS15500	COG0814	amino acid
HGG68_RS15505	COG1760	l-serine dehydratase
HGG68_RS15515	COG1454	alcohol dehydrogenase
HGG68_RS15520	COG0235	Class ii aldolase
HGG68_RS15525	COG0738	Major facilitator superfamily
HGG68_RS15530	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HGG68_RS15535	COG1070	Carbohydrate kinase
HGG68_RS15545	COG1349	DNA-binding transcription factor activity
HGG68_RS15555	COG2363	Small membrane protein
HGG68_RS15560	COG0583	DNA-binding transcription factor activity
HGG68_RS15570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGG68_RS15575	COG2166	iron-sulfur cluster assembly
HGG68_RS15580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HGG68_RS15585	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HGG68_RS15625	COG2885	chlorophyll binding
HGG68_RS15710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HGG68_RS15715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS15715	COG1263	PTS System
HGG68_RS15720	COG3711	transcriptional antiterminator
HGG68_RS15725	COG0860	N-Acetylmuramoyl-L-alanine amidase
HGG68_RS15730	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HGG68_RS15730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HGG68_RS15735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HGG68_RS15740	COG1074	ATP-dependent DNA helicase activity
HGG68_RS15745	COG1025	Belongs to the peptidase M16 family
HGG68_RS15750	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HGG68_RS15755	COG4967	type IV pilus modification protein PilV
HGG68_RS15765	COG4795	General secretion pathway protein
HGG68_RS15770	COG2165	general secretion pathway protein
HGG68_RS15785	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HGG68_RS15800	COG0861	Integral membrane protein TerC family
HGG68_RS15810	COG0667	Aldo Keto reductase
HGG68_RS15830	COG1609	Transcriptional regulator
HGG68_RS15840	COG0583	DNA-binding transcription factor activity
HGG68_RS15845	COG1794	racemase activity, acting on amino acids and derivatives
HGG68_RS15850	COG2814	Major facilitator Superfamily
HGG68_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS15865	COG0183	Belongs to the thiolase family
HGG68_RS15870	COG0814	amino acid
HGG68_RS15880	COG4942	peptidase
HGG68_RS15885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HGG68_RS15890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HGG68_RS15895	COG2080	2 iron, 2 sulfur cluster binding
HGG68_RS15900	COG3829	transcription factor binding
HGG68_RS15905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGG68_RS15910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGG68_RS15915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HGG68_RS15925	COG0549	Belongs to the carbamate kinase family
HGG68_RS15930	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HGG68_RS15930	COG3608	succinylglutamate desuccinylase aspartoacylase
HGG68_RS15935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGG68_RS15940	COG2068	MobA-Related Protein
HGG68_RS15945	COG0493	'glutamate synthase
HGG68_RS15945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS15950	COG0402	S-adenosylhomocysteine deaminase activity
HGG68_RS15955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HGG68_RS15960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HGG68_RS15960	COG2080	2 iron, 2 sulfur cluster binding
HGG68_RS15965	COG2233	PERMEase
HGG68_RS15970	COG0402	S-adenosylhomocysteine deaminase activity
HGG68_RS15975	COG2252	PERMEase
HGG68_RS15980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS15985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS15985	COG0493	'glutamate synthase
HGG68_RS15990	COG2233	PERMEase
HGG68_RS16005	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HGG68_RS16015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HGG68_RS16025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HGG68_RS16030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HGG68_RS16035	COG4974	Belongs to the 'phage' integrase family
HGG68_RS16040	COG0716	FMN binding
HGG68_RS16050	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HGG68_RS16055	COG0354	folic acid binding
HGG68_RS16060	COG1272	protein, Hemolysin III
HGG68_RS16070	COG2723	6-phospho-beta-galactosidase activity
HGG68_RS16075	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGG68_RS16075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGG68_RS16085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HGG68_RS16095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGG68_RS16100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGG68_RS16105	COG0006	proline dipeptidase activity
HGG68_RS16125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGG68_RS16135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HGG68_RS16155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HGG68_RS16155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HGG68_RS16160	COG0583	DNA-binding transcription factor activity
HGG68_RS16165	COG2968	Membrane
HGG68_RS16170	COG1279	arginine transmembrane transporter activity
HGG68_RS16175	COG0668	transmembrane transport
HGG68_RS16180	COG0191	fructose-bisphosphate aldolase activity
HGG68_RS16215	COG1122	ATPase activity
HGG68_RS16220	COG1072	(Pantothenic acid kinase))
HGG68_RS16235	COG1063	alcohol dehydrogenase
HGG68_RS16240	COG2213	PTS system mannitol-specific
HGG68_RS16245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS16250	COG0330	HflC and HflK could
HGG68_RS16255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGG68_RS16260	COG0501	Belongs to the peptidase M48B family
HGG68_RS16275	COG1166	arginine decarboxylase activity
HGG68_RS16295	COG2814	Major facilitator Superfamily
HGG68_RS16305	COG2356	endonuclease I
HGG68_RS16310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HGG68_RS16315	COG0189	ligase activity
HGG68_RS16330	COG2805	Type II/IV secretion system protein
HGG68_RS16335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGG68_RS16340	COG0762	integral membrane protein
HGG68_RS16350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGG68_RS16355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HGG68_RS16365	COG0252	asparaginase activity
HGG68_RS16375	COG3171	Protein conserved in bacteria
HGG68_RS16385	COG1194	a g-specific adenine glycosylase
HGG68_RS16390	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HGG68_RS16400	COG2211	Major facilitator Superfamily
HGG68_RS16405	COG1982	Orn Lys Arg decarboxylase major
HGG68_RS16410	COG1811	Na channel or pump
HGG68_RS16420	COG0582	viral genome integration into host DNA
HGG68_RS16440	COG3436	PFAM IS66 Orf2 family protein
HGG68_RS16455	COG5002	protein histidine kinase activity
HGG68_RS16460	COG0745	RESPONSE REGULATOR receiver
HGG68_RS16470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGG68_RS16490	COG2274	protein secretion by the type I secretion system
HGG68_RS16510	COG3436	PFAM IS66 Orf2 family protein
HGG68_RS16640	COG4584	PFAM Integrase catalytic
HGG68_RS16645	COG1484	DNA-dependent DNA replication
HGG68_RS16655	COG4771	TonB-dependent receptor
HGG68_RS16675	COG3436	PFAM IS66 Orf2 family protein
HGG68_RS16690	COG3468	outer membrane autotransporter barrel domain protein
HGG68_RS16740	COG0657	acetylesterase activity
HGG68_RS16740	COG2755	lipolytic protein G-D-S-L family
HGG68_RS16745	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HGG68_RS16750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HGG68_RS16760	COG2814	Major facilitator Superfamily
HGG68_RS16765	COG1940	carbohydrate kinase activity
HGG68_RS16770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGG68_RS16785	COG3436	PFAM IS66 Orf2 family protein
HGG68_RS16795	COG4372	Transposase
HGG68_RS16830	COG4983	Phage plasmid primase, P4 family domain protein
HGG68_RS16840	COG3468	outer membrane autotransporter barrel domain protein
HGG68_RS16855	COG2433	Pfam Transposase IS66
HGG68_RS16865	COG3436	PFAM IS66 Orf2 family protein
HGG68_RS16875	COG2020	methyltransferase activity
HGG68_RS16900	COG2003	Belongs to the UPF0758 family
HGG68_RS16955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HGG68_RS16955	COG0517	IMP dehydrogenase activity
HGG68_RS16995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGG68_RS17005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HGG68_RS17020	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HGG68_RS17035	COG3385	transposase activity
HGG68_RS17040	COG1620	l-lactate permease
HGG68_RS17045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HGG68_RS17050	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HGG68_RS17055	COG0247	lactate metabolic process
HGG68_RS17060	COG0277	FAD linked oxidase domain protein
HGG68_RS17065	COG0277	FAD linked oxidase domain protein
HGG68_RS17070	COG2186	Transcriptional regulator
HGG68_RS17075	COG0456	acetyltransferase
HGG68_RS17080	COG0318	PFAM AMP-dependent synthetase and ligase
HGG68_RS17090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGG68_RS17095	COG0156	8-amino-7-oxononanoate synthase activity
HGG68_RS17105	COG0795	lipopolysaccharide-transporting ATPase activity
HGG68_RS17110	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HGG68_RS17120	COG2244	polysaccharide biosynthetic process
HGG68_RS17125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGG68_RS17130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGG68_RS17135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGG68_RS17140	COG0306	phosphate transporter
HGG68_RS17145	COG0754	glutathionylspermidine amidase activity
HGG68_RS17150	COG0625	glutathione transferase activity
HGG68_RS17155	COG0298	carbon dioxide binding
HGG68_RS17160	COG0375	protein maturation
HGG68_RS17165	COG1773	rubredoxin
HGG68_RS17170	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HGG68_RS17175	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HGG68_RS17180	COG5557	Pfam Polysulphide reductase, NrfD
HGG68_RS17185	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS17190	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HGG68_RS17205	COG0667	Aldo Keto reductase
HGG68_RS17210	COG2862	Uncharacterized protein family, UPF0114
HGG68_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS17220	COG0848	biopolymer transport protein
HGG68_RS17225	COG0811	peptide transport
HGG68_RS17230	COG0626	cystathionine gamma-synthase activity
HGG68_RS17235	COG0586	Pfam SNARE associated Golgi protein
HGG68_RS17240	COG2207	Transcriptional regulator
HGG68_RS17245	COG1979	alcohol dehydrogenase
HGG68_RS17250	COG0656	L-ascorbic acid biosynthetic process
HGG68_RS17260	COG4238	major outer membrane lipoprotein
HGG68_RS17265	COG1032	radical SAM domain protein
HGG68_RS17270	COG2186	Transcriptional regulator
HGG68_RS17275	COG0246	Mannitol dehydrogenase
HGG68_RS17280	COG1063	alcohol dehydrogenase
HGG68_RS17285	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HGG68_RS17310	COG0204	Acyl-transferase
HGG68_RS17315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGG68_RS17320	COG4166	transmembrane transport
HGG68_RS17325	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HGG68_RS17330	COG3111	PFAM Bacterial OB fold (BOF) protein
HGG68_RS17335	COG0745	RESPONSE REGULATOR receiver
HGG68_RS17340	COG0642	Histidine kinase
HGG68_RS17355	COG2249	NAD(P)H dehydrogenase (quinone) activity
HGG68_RS17360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HGG68_RS17365	COG1737	Transcriptional regulator
HGG68_RS17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS17380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS17385	COG1120	ATPase activity
HGG68_RS17390	COG4774	siderophore transport
HGG68_RS17395	COG0187	DNA topoisomerase II activity
HGG68_RS17400	COG3150	esterase
HGG68_RS17405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HGG68_RS17410	COG3151	Protein conserved in bacteria
HGG68_RS17415	COG0494	nUDIX hydrolase
HGG68_RS17420	COG1538	Outer membrane efflux protein
HGG68_RS17430	COG0754	glutathionylspermidine amidase activity
HGG68_RS17440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HGG68_RS17450	COG3384	dioxygenase
HGG68_RS17465	COG3539	Fimbrial protein
HGG68_RS17470	COG3188	usher protein
HGG68_RS17475	COG3121	Chaperone
HGG68_RS17480	COG3539	Fimbrial protein
HGG68_RS17500	COG1585	Membrane protein implicated in regulation of membrane protease activity
HGG68_RS17505	COG2268	Band 7 protein
HGG68_RS17520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HGG68_RS17525	COG3025	triphosphatase activity
HGG68_RS17535	COG0675	Transposase, IS605 OrfB family
HGG68_RS17540	COG4991	sh3 domain protein
HGG68_RS17545	COG0617	tRNA 3'-terminal CCA addition
HGG68_RS17555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGG68_RS17575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HGG68_RS17590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HGG68_RS17600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGG68_RS17615	COG2375	cellular response to nickel ion
HGG68_RS17620	COG1695	Transcriptional regulator
HGG68_RS17625	COG0840	transmembrane signaling receptor activity
HGG68_RS17630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HGG68_RS17635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGG68_RS17640	COG1609	Transcriptional regulator
HGG68_RS17645	COG3250	beta-galactosidase activity
HGG68_RS17650	COG2731	YhcH YjgK YiaL family protein
HGG68_RS17655	COG0531	amino acid
HGG68_RS17665	COG3408	Glycogen debranching enzyme
HGG68_RS17665	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HGG68_RS17670	COG0446	pyridine nucleotide-disulphide oxidoreductase
HGG68_RS17670	COG1902	pentaerythritol trinitrate reductase activity
HGG68_RS17675	COG5499	transcription regulator containing HTH domain
HGG68_RS17690	COG1451	nucleotide metabolic process
HGG68_RS17695	COG2949	membrane
HGG68_RS17700	COG0673	inositol 2-dehydrogenase activity
HGG68_RS17705	COG0861	Integral membrane protein TerC family
HGG68_RS17710	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HGG68_RS17720	COG2721	sulfolactate sulfo-lyase activity
HGG68_RS17730	COG2271	Major facilitator Superfamily
HGG68_RS17735	COG2186	Transcriptional regulator
HGG68_RS17740	COG0586	Pfam SNARE associated Golgi protein
HGG68_RS17750	COG1422	Protein of unknown function (DUF1090)
HGG68_RS17755	COG4575	ribosome binding
HGG68_RS17760	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HGG68_RS17770	COG2259	Doxx family
HGG68_RS17775	COG0435	Glutathione S-transferase
HGG68_RS17780	COG3152	Membrane
HGG68_RS17785	COG0583	DNA-binding transcription factor activity
HGG68_RS17790	COG1741	Belongs to the pirin family
HGG68_RS17805	COG0814	amino acid
HGG68_RS17810	COG1760	l-serine dehydratase
HGG68_RS17815	COG0251	oxidation-reduction process
HGG68_RS17820	COG1882	Formate acetyltransferase
HGG68_RS17825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGG68_RS17835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGG68_RS17840	COG0583	DNA-binding transcription factor activity
HGG68_RS17855	COG1929	Belongs to the glycerate kinase type-1 family
HGG68_RS17860	COG2084	Dehydrogenase
HGG68_RS17865	COG3836	Belongs to the HpcH HpaI aldolase family
HGG68_RS17870	COG2271	Major facilitator Superfamily
HGG68_RS17875	COG2721	sulfolactate sulfo-lyase activity
HGG68_RS17880	COG2002	toxin-antitoxin pair type II binding
HGG68_RS17890	COG1349	DNA-binding transcription factor activity
HGG68_RS17900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS17910	COG3716	PTS system mannose fructose sorbose family IID component
HGG68_RS17915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS17920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGG68_RS17925	COG2222	sugar isomerase
HGG68_RS17935	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS17940	COG3715	PTS system
HGG68_RS17945	COG3716	PTS system mannose fructose sorbose family IID component
HGG68_RS17950	COG0363	glucosamine-6-phosphate deaminase activity
HGG68_RS17955	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGG68_RS17960	COG3107	peptidoglycan biosynthetic process
HGG68_RS17975	COG2823	Periplasmic or secreted lipoprotein
HGG68_RS17980	COG0701	Predicted permease
HGG68_RS17985	COG0702	epimerase
HGG68_RS18000	COG3153	acetyltransferase
HGG68_RS18005	COG3154	lipid carrier protein
HGG68_RS18010	COG0826	peptidase U32
HGG68_RS18015	COG0826	peptidase U32
HGG68_RS18020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGG68_RS18025	COG0814	amino acid
HGG68_RS18030	COG0513	Belongs to the DEAD box helicase family
HGG68_RS18070	COG0195	Participates in both transcription termination and antitermination
HGG68_RS18090	COG2194	sulfuric ester hydrolase activity
HGG68_RS18100	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HGG68_RS18110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HGG68_RS18115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGG68_RS18125	COG1534	Rna-binding protein
HGG68_RS18130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HGG68_RS18135	COG2027	D-alanyl-D-alanine carboxypeptidase
HGG68_RS18145	COG0697	spore germination
HGG68_RS18160	COG0142	geranyltranstransferase activity
HGG68_RS18165	COG3423	Transcriptional regulator
HGG68_RS18175	COG5007	Belongs to the BolA IbaG family
HGG68_RS18180	COG3113	response to antibiotic
HGG68_RS18185	COG2854	intermembrane phospholipid transfer
HGG68_RS18190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HGG68_RS18195	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HGG68_RS18200	COG1127	ABC transporter
HGG68_RS18205	COG0530	calcium, potassium:sodium antiporter activity
HGG68_RS18210	COG0517	IMP dehydrogenase activity
HGG68_RS18210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HGG68_RS18215	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HGG68_RS18220	COG3117	lipopolysaccharide transmembrane transporter activity
HGG68_RS18225	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HGG68_RS18230	COG1137	ATPase activity
HGG68_RS18235	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HGG68_RS18240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGG68_RS18255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS18260	COG0515	serine threonine protein kinase
HGG68_RS18270	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HGG68_RS18275	COG5002	protein histidine kinase activity
HGG68_RS18275	COG2198	Histidine kinase
HGG68_RS18275	COG0784	Response regulator, receiver
HGG68_RS18280	COG1242	4 iron, 4 sulfur cluster binding
HGG68_RS18285	COG0069	glutamate synthase activity
HGG68_RS18285	COG0067	glutamate synthase
HGG68_RS18285	COG0070	glutamate synthase
HGG68_RS18290	COG0493	'glutamate synthase
HGG68_RS18295	COG2731	YhcH YjgK YiaL family protein
HGG68_RS18300	COG1940	carbohydrate kinase activity
HGG68_RS18310	COG2814	Major facilitator Superfamily
HGG68_RS18315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGG68_RS18325	COG2969	positive regulation of protein catabolic process
HGG68_RS18330	COG0625	glutathione transferase activity
HGG68_RS18345	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HGG68_RS18350	COG3105	Protein conserved in bacteria
HGG68_RS18355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGG68_RS18360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGG68_RS18380	COG2732	(Barnase) inhibitor
HGG68_RS18385	COG1289	transmembrane transporter activity
HGG68_RS18400	COG0583	DNA-binding transcription factor activity
HGG68_RS18405	COG0312	modulator of DNA gyrase
HGG68_RS18410	COG3164	Protein of unknown function
HGG68_RS18415	COG1530	ribonuclease E activity
HGG68_RS18425	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HGG68_RS18430	COG1792	Involved in formation and maintenance of cell shape
HGG68_RS18435	COG1077	Cell shape determining protein MreB Mrl
HGG68_RS18440	COG2199	diguanylate cyclase activity
HGG68_RS18440	COG2200	EAL domain
HGG68_RS18445	COG0604	alcohol dehydrogenase
HGG68_RS18455	COG0511	ligase activity, forming carbon-carbon bonds
HGG68_RS18460	COG0439	Biotin carboxylase
HGG68_RS18470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS18475	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS18480	COG1129	ABC transporter
HGG68_RS18485	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS18495	COG1349	DNA-binding transcription factor activity
HGG68_RS18500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS18505	COG3924	membrane
HGG68_RS18510	COG4145	pantothenate transmembrane transporter activity
HGG68_RS18520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGG68_RS18530	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HGG68_RS18540	COG1309	transcriptional regulator
HGG68_RS18545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS18550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGG68_RS18560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGG68_RS18565	COG4597	amino acid ABC transporter
HGG68_RS18570	COG0765	amino acid transport
HGG68_RS18575	COG1126	abc transporter atp-binding protein
HGG68_RS18615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGG68_RS18625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGG68_RS18630	COG0009	L-threonylcarbamoyladenylate synthase
HGG68_RS18635	COG0551	DNA topoisomerase type I activity
HGG68_RS18640	COG2922	Belongs to the Smg family
HGG68_RS18645	COG0758	DNA mediated transformation
HGG68_RS18655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGG68_RS18660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGG68_RS18660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGG68_RS18665	COG0569	domain protein
HGG68_RS18675	COG3036	rescue of stalled ribosome
HGG68_RS18680	COG0789	Transcriptional regulator
HGG68_RS18720	COG0201	protein transport
HGG68_RS18810	COG0089	rRNA binding
HGG68_RS18835	COG3409	Peptidoglycan-binding domain 1 protein
HGG68_RS18835	COG3267	Type II secretory pathway component ExeA
HGG68_RS18840	COG3031	protein transport across the cell outer membrane
HGG68_RS18845	COG1450	Type ii and iii secretion system protein
HGG68_RS18850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HGG68_RS18855	COG1459	type II secretion system
HGG68_RS18860	COG2165	general secretion pathway protein
HGG68_RS18865	COG2165	general secretion pathway protein
HGG68_RS18870	COG2165	general secretion pathway protein
HGG68_RS18875	COG4795	General secretion pathway protein
HGG68_RS18885	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HGG68_RS18890	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HGG68_RS18895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HGG68_RS18900	COG2193	ferroxidase activity
HGG68_RS18905	COG2906	2 iron, 2 sulfur cluster binding
HGG68_RS18910	COG3979	chitinase
HGG68_RS18950	COG2964	Protein conserved in bacteria
HGG68_RS18955	COG0545	Peptidyl-prolyl cis-trans isomerase
HGG68_RS18965	COG1047	Peptidyl-prolyl cis-trans
HGG68_RS18970	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HGG68_RS18985	COG0488	(ABC) transporter
HGG68_RS18990	COG0429	hydrolase of the alpha beta-hydrolase fold
HGG68_RS19000	COG3954	Phosphoribulokinase
HGG68_RS19005	COG1765	OsmC-like protein
HGG68_RS19010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGG68_RS19015	COG1289	transmembrane transporter activity
HGG68_RS19020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HGG68_RS19025	COG0512	Glutamine amidotransferase of anthranilate synthase
HGG68_RS19030	COG2184	nucleotidyltransferase activity
HGG68_RS19040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGG68_RS19050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGG68_RS19055	COG2146	nitrite reductase [NAD(P)H] activity
HGG68_RS19060	COG2116	formate transmembrane transporter activity
HGG68_RS19075	COG0626	cystathionine gamma-synthase activity
HGG68_RS19090	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HGG68_RS19095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGG68_RS19100	COG3457	Alanine racemase
HGG68_RS19110	COG2188	Transcriptional regulator
HGG68_RS19115	COG0180	Tryptophanyl-tRNA synthetase
HGG68_RS19120	COG0546	phosphoglycolate phosphatase activity
HGG68_RS19125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HGG68_RS19130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HGG68_RS19135	COG3266	domain, Protein
HGG68_RS19150	COG4796	Type ii and iii secretion system protein
HGG68_RS19165	COG3166	PFAM Fimbrial assembly family protein
HGG68_RS19170	COG4972	Pilus assembly protein
HGG68_RS19175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HGG68_RS19180	COG0494	nUDIX hydrolase
HGG68_RS19190	COG1011	Hydrolase
HGG68_RS19195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HGG68_RS19205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HGG68_RS19210	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HGG68_RS19235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HGG68_RS19240	COG2183	response to ionizing radiation
HGG68_RS19245	COG1918	ferrous iron import across plasma membrane
HGG68_RS19250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HGG68_RS19265	COG0596	Alpha beta hydrolase
HGG68_RS19270	COG1040	competence protein
HGG68_RS19280	COG2610	gluconate transmembrane transporter activity
HGG68_RS19285	COG1640	4-alpha-glucanotransferase
HGG68_RS19290	COG0058	SHG alpha-glucan phosphorylase activity
HGG68_RS19295	COG2909	trisaccharide binding
HGG68_RS19300	COG0430	RNA-3'-phosphate cyclase activity
HGG68_RS19305	COG1690	Belongs to the RtcB family
HGG68_RS19310	COG4650	regulator
HGG68_RS19315	COG1349	DNA-binding transcription factor activity
HGG68_RS19330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HGG68_RS19370	COG3188	usher protein
HGG68_RS19375	COG3121	Chaperone
HGG68_RS19385	COG0058	SHG alpha-glucan phosphorylase activity
HGG68_RS19400	COG1523	belongs to the glycosyl hydrolase 13 family
HGG68_RS19405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGG68_RS19410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGG68_RS19415	COG2095	MarC family integral membrane protein
HGG68_RS19425	COG0514	ATP-dependent DNA helicase (RecQ)
HGG68_RS19430	COG2610	gluconate transmembrane transporter activity
HGG68_RS19435	COG3265	gluconokinase activity
HGG68_RS19440	COG1609	Transcriptional regulator
HGG68_RS19445	COG1741	Belongs to the pirin family
HGG68_RS19450	COG0673	inositol 2-dehydrogenase activity
HGG68_RS19455	COG1247	-acetyltransferase
HGG68_RS19460	COG1247	-acetyltransferase
HGG68_RS19465	COG3157	Type VI secretion system effector, Hcp
HGG68_RS19485	COG0405	Gamma-glutamyltransferase
HGG68_RS19495	COG0584	glycerophosphoryl diester phosphodiesterase
HGG68_RS19500	COG3842	ATPase activity
HGG68_RS19510	COG1175	transmembrane transport
HGG68_RS19520	COG0410	ABC transporter
HGG68_RS19525	COG0411	ABC transporter
HGG68_RS19530	COG4177	L-phenylalanine transmembrane transporter activity
HGG68_RS19535	COG0559	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS19540	COG0683	leucine binding
HGG68_RS19545	COG0456	acetyltransferase
HGG68_RS19550	COG0683	leucine binding
HGG68_RS19555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGG68_RS19560	COG2177	Part of the ABC transporter FtsEX involved in
HGG68_RS19565	COG2884	Cell division ATP-binding protein ftsE
HGG68_RS19570	COG0552	protein localization to endoplasmic reticulum
HGG68_RS19575	COG0742	ribosomal rna small subunit methyltransferase
HGG68_RS19580	COG3776	membrane
HGG68_RS19590	COG3714	YhhN family
HGG68_RS19605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HGG68_RS19615	COG0477	Major facilitator Superfamily
HGG68_RS19620	COG0628	permease
HGG68_RS19625	COG2091	lysine biosynthetic process via aminoadipic acid
HGG68_RS19630	COG0747	negative chemotaxis
HGG68_RS19635	COG0601	transmembrane transport
HGG68_RS19640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGG68_RS19645	COG0444	Belongs to the ABC transporter superfamily
HGG68_RS19660	COG2188	Transcriptional regulator
HGG68_RS19670	COG3414	Phosphotransferase system galactitol-specific IIB component
HGG68_RS19675	COG3775	system Galactitol-specific IIC component
HGG68_RS19690	COG0191	fructose-bisphosphate aldolase activity
HGG68_RS19695	COG0842	Transport permease protein
HGG68_RS19700	COG0842	Transport permease protein
HGG68_RS19700	COG1129	ABC transporter
HGG68_RS19705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS19715	COG2081	HI0933 family
HGG68_RS19720	COG0306	phosphate transporter
HGG68_RS19730	COG0589	response to stress
HGG68_RS19735	COG3104	oligopeptide transport
HGG68_RS19745	COG0339	signal peptide processing
HGG68_RS19750	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HGG68_RS19755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGG68_RS19765	COG1393	Belongs to the ArsC family
HGG68_RS19775	COG3065	identical protein binding
HGG68_RS19780	COG2197	response regulator
HGG68_RS19785	COG3720	iron ion transport
HGG68_RS19790	COG4771	TonB-dependent receptor
HGG68_RS19805	COG3721	Heme iron utilization protein
HGG68_RS19815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGG68_RS19825	COG1285	pathogenesis
HGG68_RS19840	COG3247	response to pH
HGG68_RS19845	COG2771	luxR family
HGG68_RS19855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGG68_RS19860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGG68_RS19865	COG2207	Transcriptional regulator
HGG68_RS19870	COG2207	Transcriptional regulator
HGG68_RS19875	COG0076	glutamate decarboxylase activity
HGG68_RS19880	COG1858	cytochrome C peroxidase
HGG68_RS19890	COG2197	response regulator
HGG68_RS19895	COG0583	DNA-binding transcription factor activity
HGG68_RS19900	COG1295	ribonuclease BN
HGG68_RS19905	COG0477	Major facilitator Superfamily
HGG68_RS19910	COG2982	Protein involved in outer membrane biogenesis
HGG68_RS19915	COG2200	EAL domain
HGG68_RS19920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS19925	COG0612	Peptidase, M16
HGG68_RS19935	COG2199	diguanylate cyclase activity
HGG68_RS19935	COG2200	EAL domain
HGG68_RS19940	COG3118	belongs to the thioredoxin family
HGG68_RS19940	COG0457	Tetratricopeptide repeat
HGG68_RS19945	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HGG68_RS19950	COG1215	transferase activity, transferring glycosyl groups
HGG68_RS19955	COG1215	transferase activity, transferring glycosyl groups
HGG68_RS19980	COG2194	sulfuric ester hydrolase activity
HGG68_RS19995	COG0814	amino acid
HGG68_RS20000	COG4608	Belongs to the ABC transporter superfamily
HGG68_RS20005	COG0444	Belongs to the ABC transporter superfamily
HGG68_RS20010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGG68_RS20015	COG0601	transmembrane transport
HGG68_RS20025	COG0747	negative chemotaxis
HGG68_RS20035	COG2194	sulfuric ester hydrolase activity
HGG68_RS20040	COG2223	nitrite transmembrane transporter activity
HGG68_RS20045	COG5571	outer membrane autotransporter
HGG68_RS20050	COG2818	Glycosylase
HGG68_RS20055	COG0456	acetyltransferase
HGG68_RS20060	COG0243	molybdopterin cofactor binding
HGG68_RS20065	COG2885	chlorophyll binding
HGG68_RS20070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGG68_RS20080	COG2944	sequence-specific DNA binding
HGG68_RS20085	COG1278	Cold shock
HGG68_RS20110	COG3274	enterobacterial common antigen metabolic process
HGG68_RS20115	COG4682	membrane
HGG68_RS20120	COG4682	membrane
HGG68_RS20125	COG1070	Carbohydrate kinase
HGG68_RS20135	COG4213	ABC transporter substrate-binding protein
HGG68_RS20145	COG4214	carbohydrate transport
HGG68_RS20150	COG1609	Transcriptional regulator
HGG68_RS20150	COG2207	Transcriptional regulator
HGG68_RS20155	COG2992	FlgJ-related protein
HGG68_RS20160	COG0366	Alpha amylase catalytic
HGG68_RS20165	COG3977	Valine--pyruvate aminotransferase
HGG68_RS20170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGG68_RS20175	COG1414	Transcriptional regulator
HGG68_RS20185	COG2731	YhcH YjgK YiaL family protein
HGG68_RS20195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HGG68_RS20200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HGG68_RS20205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HGG68_RS20210	COG1070	Carbohydrate kinase
HGG68_RS20215	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HGG68_RS20220	COG3623	hexulose-6-phosphate isomerase
HGG68_RS20225	COG0235	Class ii aldolase
HGG68_RS20230	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS20240	COG1454	alcohol dehydrogenase
HGG68_RS20245	COG3276	selenocysteine insertion sequence binding
HGG68_RS20255	COG0625	glutathione transferase activity
HGG68_RS20260	COG1566	PFAM secretion protein HlyD family protein
HGG68_RS20270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS20270	COG2213	PTS system mannitol-specific
HGG68_RS20280	COG3722	fumarate hydratase activity
HGG68_RS20300	COG5295	Hep Hag repeat protein
HGG68_RS20305	COG1620	l-lactate permease
HGG68_RS20310	COG2186	Transcriptional regulator
HGG68_RS20320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HGG68_RS20325	COG1045	serine acetyltransferase
HGG68_RS20340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HGG68_RS20345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGG68_RS20350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGG68_RS20355	COG4942	peptidase
HGG68_RS20360	COG2861	carbohydrate metabolic process
HGG68_RS20365	COG1216	Glycosyl transferase, family 2
HGG68_RS20375	COG0156	8-amino-7-oxononanoate synthase activity
HGG68_RS20385	COG0859	PFAM glycosyl transferase family 9
HGG68_RS20390	COG0859	PFAM glycosyl transferase family 9
HGG68_RS20395	COG3307	-O-antigen
HGG68_RS20400	COG1216	Glycosyl transferase, family 2
HGG68_RS20405	COG1442	glycosyl transferase family 8
HGG68_RS20410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HGG68_RS20425	COG0515	serine threonine protein kinase
HGG68_RS20430	COG0438	transferase activity, transferring glycosyl groups
HGG68_RS20435	COG0859	PFAM glycosyl transferase family 9
HGG68_RS20440	COG1519	Transferase
HGG68_RS20450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HGG68_RS20470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGG68_RS20495	COG1561	YicC-like family, N-terminal region
HGG68_RS20500	COG3645	SOS response
HGG68_RS20505	COG2860	membrane
HGG68_RS20510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGG68_RS20515	COG0194	GDP metabolic process
HGG68_RS20525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGG68_RS20530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGG68_RS20535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGG68_RS20540	COG0786	glutamate:sodium symporter activity
HGG68_RS20545	COG2233	PERMEase
HGG68_RS20550	COG2982	Protein involved in outer membrane biogenesis
HGG68_RS20560	COG1940	carbohydrate kinase activity
HGG68_RS20565	COG0191	fructose-bisphosphate aldolase activity
HGG68_RS20575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS20575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS20580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS20585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS20585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS20585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS20590	COG3711	transcriptional antiterminator
HGG68_RS20595	COG1501	Belongs to the glycosyl hydrolase 31 family
HGG68_RS20600	COG2211	Major facilitator Superfamily
HGG68_RS20610	COG0582	viral genome integration into host DNA
HGG68_RS20620	COG1609	Transcriptional regulator
HGG68_RS20625	COG2271	Major facilitator Superfamily
HGG68_RS20640	COG0531	amino acid
HGG68_RS20645	COG1982	Orn Lys Arg decarboxylase major
HGG68_RS20650	COG0531	amino acid
HGG68_RS20660	COG0604	alcohol dehydrogenase
HGG68_RS20670	COG2826	transposase and inactivated derivatives, IS30 family
HGG68_RS20725	COG2831	hemolysin activation secretion protein
HGG68_RS20750	COG4869	propanediol catabolic process
HGG68_RS20755	COG4820	ethanolamine utilization protein (EutJ)
HGG68_RS20790	COG1012	belongs to the aldehyde dehydrogenase family
HGG68_RS20800	COG0693	protein deglycase activity
HGG68_RS20805	COG1882	Formate acetyltransferase
HGG68_RS20810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGG68_RS20825	COG3344	reverse transcriptase
HGG68_RS20830	COG2972	Histidine kinase
HGG68_RS20835	COG2207	Transcriptional regulator
HGG68_RS20840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGG68_RS20895	COG3596	GTP binding
HGG68_RS20900	COG2378	regulation of single-species biofilm formation
HGG68_RS20925	COG2003	Belongs to the UPF0758 family
HGG68_RS20965	COG0697	spore germination
HGG68_RS20970	COG1464	Belongs to the NlpA lipoprotein family
HGG68_RS20980	COG2814	Major facilitator Superfamily
HGG68_RS20990	COG2252	PERMEase
HGG68_RS20995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HGG68_RS21000	COG2271	Major facilitator Superfamily
HGG68_RS21005	COG2271	Major facilitator Superfamily
HGG68_RS21010	COG3851	Histidine kinase
HGG68_RS21015	COG2197	response regulator
HGG68_RS21025	COG0440	acetolactate synthase activity
HGG68_RS21030	COG0028	Belongs to the TPP enzyme family
HGG68_RS21040	COG2814	Major facilitator Superfamily
HGG68_RS21045	COG0641	radical SAM
HGG68_RS21055	COG2149	membrane
HGG68_RS21060	COG3119	arylsulfatase activity
HGG68_RS21065	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGG68_RS21070	COG2207	Transcriptional regulator
HGG68_RS21090	COG5645	(Lipo)protein
HGG68_RS21095	COG0823	Involved in the tonB-independent uptake of proteins
HGG68_RS21100	COG0644	oxidoreductase
HGG68_RS21105	COG2271	Major facilitator Superfamily
HGG68_RS21115	COG0800	Aldolase
HGG68_RS21120	COG3734	2-keto-3-deoxy-galactonokinase
HGG68_RS21125	COG2186	Transcriptional regulator
HGG68_RS21135	COG0561	phosphatase activity
HGG68_RS21140	COG3753	Protein conserved in bacteria
HGG68_RS21145	COG0187	DNA topoisomerase II activity
HGG68_RS21155	COG0592	DNA-directed DNA polymerase activity
HGG68_RS21175	COG0594	ribonuclease P activity
HGG68_RS21200	COG3033	Beta-eliminating lyase
HGG68_RS21205	COG0814	amino acid
HGG68_RS21215	COG0583	DNA-binding transcription factor activity
HGG68_RS21220	COG2091	lysine biosynthetic process via aminoadipic acid
HGG68_RS21225	COG0431	NADPH-dependent FMN reductase
HGG68_RS21230	COG2252	PERMEase
HGG68_RS21235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HGG68_RS21245	COG0363	glucosamine-6-phosphate deaminase activity
HGG68_RS21250	COG2382	esterase
HGG68_RS21255	COG4580	involved in the transport of maltose and maltodextrins
HGG68_RS21260	COG2723	6-phospho-beta-galactosidase activity
HGG68_RS21265	COG2190	(PTS) system
HGG68_RS21265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS21265	COG1263	PTS System
HGG68_RS21270	COG3711	transcriptional antiterminator
HGG68_RS21275	COG0704	Plays a role in the regulation of phosphate uptake
HGG68_RS21280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HGG68_RS21285	COG0581	inorganic phosphate transmembrane transporter activity
HGG68_RS21290	COG0573	inorganic phosphate transmembrane transporter activity
HGG68_RS21295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HGG68_RS21300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HGG68_RS21305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGG68_RS21350	COG3312	ion transport
HGG68_RS21365	COG0716	FMN binding
HGG68_RS21370	COG1522	sequence-specific DNA binding
HGG68_RS21385	COG0714	Associated with various cellular activities
HGG68_RS21395	COG1869	D-ribose catabolic process
HGG68_RS21400	COG1129	ABC transporter
HGG68_RS21405	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS21410	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS21415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS21420	COG1609	Transcriptional regulator
HGG68_RS21425	COG0477	Major facilitator Superfamily
HGG68_RS21430	COG2186	Transcriptional regulator
HGG68_RS21470	COG3085	chromosome segregation
HGG68_RS21475	COG0606	chelatase, subunit chli
HGG68_RS21495	COG3978	acetolactate synthase activity
HGG68_RS21500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HGG68_RS21505	COG0129	dihydroxy-acid dehydratase activity
HGG68_RS21510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGG68_RS21515	COG0583	DNA-binding transcription factor activity
HGG68_RS21525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HGG68_RS21530	COG0210	DNA helicase
HGG68_RS21545	COG3118	belongs to the thioredoxin family
HGG68_RS21555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HGG68_RS21560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGG68_RS21565	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HGG68_RS21570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HGG68_RS21575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HGG68_RS21580	COG1088	dTDP-glucose 4,6-dehydratase activity
HGG68_RS21585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGG68_RS21590	COG0456	acetyltransferase
HGG68_RS21595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HGG68_RS21600	COG2244	polysaccharide biosynthetic process
HGG68_RS21605	COG1819	glycosyl
HGG68_RS21620	COG1113	amino acid transport
HGG68_RS21645	COG0641	radical SAM
HGG68_RS21650	COG3119	arylsulfatase activity
HGG68_RS21655	COG3071	HemY protein
HGG68_RS21660	COG2959	enzyme of heme biosynthesis
HGG68_RS21665	COG1587	Uroporphyrinogen-III synthase
HGG68_RS21670	COG0181	hydroxymethylbilane synthase activity
HGG68_RS21675	COG3072	Adenylate cyclase
HGG68_RS21680	COG1965	Belongs to the frataxin family
HGG68_RS21695	COG5567	small periplasmic lipoprotein
HGG68_RS21700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGG68_RS21705	COG3159	Protein conserved in bacteria
HGG68_RS21715	COG1011	Hydrolase
HGG68_RS21720	COG0210	DNA helicase
HGG68_RS21725	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HGG68_RS21730	COG3698	Phosphodiester glycosidase
HGG68_RS21735	COG0598	Magnesium transport protein CorA
HGG68_RS21750	COG2962	Rard protein
HGG68_RS21755	COG2050	protein possibly involved in aromatic compounds catabolism
HGG68_RS21760	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HGG68_RS21765	COG0514	ATP-dependent DNA helicase (RecQ)
HGG68_RS21770	COG1280	lysine exporter protein (LysE YggA)
HGG68_RS21775	COG1280	lysine exporter protein (LysE YggA)
HGG68_RS21780	COG2267	carboxylic ester hydrolase activity
HGG68_RS21785	COG0561	phosphatase activity
HGG68_RS21790	COG0697	spore germination
HGG68_RS21795	COG0583	DNA-binding transcription factor activity
HGG68_RS21800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGG68_RS21810	COG3157	Type VI secretion system effector, Hcp
HGG68_RS21815	COG3157	Type VI secretion system effector, Hcp
HGG68_RS21825	COG2190	(PTS) system
HGG68_RS21825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS21825	COG1263	PTS System
HGG68_RS21830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGG68_RS21835	COG1737	Transcriptional regulator
HGG68_RS21840	COG0583	DNA-binding transcription factor activity
HGG68_RS21845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HGG68_RS21855	COG0549	Belongs to the carbamate kinase family
HGG68_RS21860	COG1304	FMN binding
HGG68_RS21865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGG68_RS21875	COG1335	isochorismatase
HGG68_RS21880	COG0412	Dienelactone hydrolase
HGG68_RS21885	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HGG68_RS21905	COG0800	Aldolase
HGG68_RS21910	COG3734	2-keto-3-deoxy-galactonokinase
HGG68_RS21915	COG1414	Transcriptional regulator
HGG68_RS21920	COG1322	Protein conserved in bacteria
HGG68_RS21930	COG3165	ubiquinone biosynthetic process from chorismate
HGG68_RS21940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGG68_RS21950	COG0805	protein transport
HGG68_RS21965	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HGG68_RS21970	COG0543	2 iron, 2 sulfur cluster binding
HGG68_RS21975	COG0183	Belongs to the thiolase family
HGG68_RS21980	COG1250	3-hydroxyacyl-CoA dehydrogenase
HGG68_RS21980	COG1024	Enoyl-CoA hydratase
HGG68_RS21990	COG1739	Uncharacterized protein family UPF0029
HGG68_RS21995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HGG68_RS22000	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HGG68_RS22025	COG1763	Mo-molybdopterin cofactor biosynthetic process
HGG68_RS22030	COG0746	molybdenum cofactor guanylyltransferase activity
HGG68_RS22035	COG3084	Protein conserved in bacteria
HGG68_RS22040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HGG68_RS22045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HGG68_RS22050	COG5339	Protein conserved in bacteria
HGG68_RS22055	COG0204	Acyl-transferase
HGG68_RS22060	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGG68_RS22060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGG68_RS22075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HGG68_RS22085	COG2204	response regulator
HGG68_RS22090	COG3852	Histidine kinase
HGG68_RS22095	COG0174	glutamine synthetase
HGG68_RS22100	COG1217	gtp-binding protein TYPA
HGG68_RS22105	COG2188	Transcriptional regulator
HGG68_RS22110	COG1082	Xylose isomerase domain protein TIM barrel
HGG68_RS22115	COG2271	Major facilitator Superfamily
HGG68_RS22120	COG1349	DNA-binding transcription factor activity
HGG68_RS22125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGG68_RS22130	COG2084	Dehydrogenase
HGG68_RS22135	COG3684	Belongs to the aldolase LacD family
HGG68_RS22140	COG1063	alcohol dehydrogenase
HGG68_RS22150	COG0477	Major facilitator Superfamily
HGG68_RS22160	COG1011	Hydrolase
HGG68_RS22175	COG0456	acetyltransferase
HGG68_RS22185	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HGG68_RS22210	COG2864	formate dehydrogenase
HGG68_RS22215	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS22225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HGG68_RS22245	COG0235	Class ii aldolase
HGG68_RS22250	COG4806	L-rhamnose isomerase
HGG68_RS22260	COG4977	sequence-specific DNA binding
HGG68_RS22275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HGG68_RS22285	COG2258	MOSC domain
HGG68_RS22290	COG2205	protein histidine kinase activity
HGG68_RS22295	COG0745	RESPONSE REGULATOR receiver
HGG68_RS22300	COG3678	ATP-independent chaperone mediated protein folding
HGG68_RS22315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HGG68_RS22335	COG3152	Membrane
HGG68_RS22340	COG3691	Protein conserved in bacteria
HGG68_RS22345	COG0589	response to stress
HGG68_RS22355	COG1494	fructose-1,6-bisphosphatase
HGG68_RS22360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGG68_RS22365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HGG68_RS22380	COG1575	Belongs to the MenA family. Type 1 subfamily
HGG68_RS22395	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HGG68_RS22400	COG1609	Transcriptional regulator
HGG68_RS22405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGG68_RS22415	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HGG68_RS22425	COG0626	cystathionine gamma-synthase activity
HGG68_RS22430	COG0527	aspartate kinase activity
HGG68_RS22430	COG0460	homoserine dehydrogenase
HGG68_RS22440	COG0737	Belongs to the 5'-nucleotidase family
HGG68_RS22445	COG0737	Belongs to the 5'-nucleotidase family
HGG68_RS22455	COG0737	Belongs to the 5'-nucleotidase family
HGG68_RS22460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HGG68_RS22470	COG0697	spore germination
HGG68_RS22475	COG3738	Protein conserved in bacteria
HGG68_RS22480	COG0371	Dehydrogenase
HGG68_RS22485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGG68_RS22490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS22490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGG68_RS22490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS22495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS22500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS22505	COG1882	Formate acetyltransferase
HGG68_RS22510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGG68_RS22515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HGG68_RS22520	COG2207	Transcriptional regulator
HGG68_RS22525	COG2194	sulfuric ester hydrolase activity
HGG68_RS22540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGG68_RS22545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HGG68_RS22555	COG4948	Mandelate Racemase Muconate Lactonizing
HGG68_RS22560	COG2271	Major facilitator Superfamily
HGG68_RS22565	COG0583	DNA-binding transcription factor activity
HGG68_RS22575	COG1473	amidohydrolase
HGG68_RS22580	COG0477	Major facilitator Superfamily
HGG68_RS22595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGG68_RS22630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HGG68_RS22635	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HGG68_RS22635	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HGG68_RS22670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HGG68_RS22675	COG0250	Participates in transcription elongation, termination and antitermination
HGG68_RS22710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HGG68_RS22715	COG2022	thiamine diphosphate biosynthetic process
HGG68_RS22720	COG2104	thiamine diphosphate biosynthetic process
HGG68_RS22725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HGG68_RS22730	COG0352	thiamine-phosphate diphosphorylase activity
HGG68_RS22735	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HGG68_RS22740	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HGG68_RS22760	COG3068	Protein conserved in bacteria
HGG68_RS22775	COG3678	ATP-independent chaperone mediated protein folding
HGG68_RS22780	COG4191	Histidine kinase
HGG68_RS22785	COG2204	response regulator
HGG68_RS22790	COG0151	Belongs to the GarS family
HGG68_RS22795	COG0138	bifunctional purine biosynthesis protein purh
HGG68_RS22830	COG0456	acetyltransferase
HGG68_RS22840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HGG68_RS22845	COG2224	Isocitrate lyase
HGG68_RS22855	COG1414	Transcriptional regulator
HGG68_RS22860	COG1410	methionine synthase
HGG68_RS22860	COG0646	methionine synthase
HGG68_RS22875	COG1283	sodium-dependent phosphate transmembrane transporter activity
HGG68_RS22920	COG1187	pseudouridine synthase activity
HGG68_RS22930	COG0527	aspartate kinase activity
HGG68_RS22955	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGG68_RS22970	COG3833	ABC-type maltose transport systems, permease component
HGG68_RS22975	COG1175	transmembrane transport
HGG68_RS22980	COG2182	Extracellular solute-binding protein
HGG68_RS22985	COG3842	ATPase activity
HGG68_RS23015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HGG68_RS23025	COG0534	Mate efflux family protein
HGG68_RS23030	COG3237	CsbD-like
HGG68_RS23035	COG0735	belongs to the Fur family
HGG68_RS23040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGG68_RS23050	COG0604	alcohol dehydrogenase
HGG68_RS23055	COG1053	succinate dehydrogenase
HGG68_RS23060	COG0477	Major facilitator Superfamily
HGG68_RS23065	COG1024	Enoyl-CoA hydratase
HGG68_RS23075	COG1609	Transcriptional regulator
HGG68_RS23080	COG0305	Participates in initiation and elongation during chromosome replication
HGG68_RS23090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGG68_RS23095	COG3201	nicotinamide mononucleotide transporter
HGG68_RS23105	COG1448	Aminotransferase
HGG68_RS23110	COG0567	Dehydrogenase, E1 component
HGG68_RS23120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGG68_RS23125	COG0045	succinate-CoA ligase (ADP-forming) activity
HGG68_RS23130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGG68_RS23135	COG0471	metal ion transport
HGG68_RS23140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HGG68_RS23145	COG2204	response regulator
HGG68_RS23155	COG3700	Belongs to the class B bacterial acid phosphatase family
HGG68_RS23160	COG0432	Pfam Uncharacterised protein family UPF0047
HGG68_RS23165	COG2315	Protein conserved in bacteria
HGG68_RS23170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HGG68_RS23175	COG0629	single-stranded DNA binding
HGG68_RS23185	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HGG68_RS23190	COG2207	Transcriptional regulator
HGG68_RS23195	COG0789	Transcriptional regulator
HGG68_RS23200	COG2252	PERMEase
HGG68_RS23205	COG0025	NhaP-type Na H and K H
HGG68_RS23210	COG0583	DNA-binding transcription factor activity
HGG68_RS23215	COG1380	Effector of murein hydrolase LrgA
HGG68_RS23220	COG1346	cytolysis
HGG68_RS23225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGG68_RS23230	COG3162	membrane
HGG68_RS23235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HGG68_RS23245	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HGG68_RS23250	COG0437	4 iron, 4 sulfur cluster binding
HGG68_RS23255	COG3301	Polysulphide reductase, NrfD
HGG68_RS23260	COG1138	Cytochrome C-type biogenesis protein
HGG68_RS23265	COG3088	subunit of a heme lyase
HGG68_RS23270	COG4235	cytochrome complex assembly
HGG68_RS23275	COG1301	dicarboxylic acid transport
HGG68_RS23280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HGG68_RS23285	COG4608	Belongs to the ABC transporter superfamily
HGG68_RS23290	COG0444	Belongs to the ABC transporter superfamily
HGG68_RS23295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGG68_RS23300	COG0601	transmembrane transport
HGG68_RS23315	COG1538	Outer membrane efflux protein
HGG68_RS23320	COG1289	transmembrane transporter activity
HGG68_RS23325	COG1566	PFAM secretion protein HlyD family protein
HGG68_RS23335	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HGG68_RS23340	COG1940	carbohydrate kinase activity
HGG68_RS23345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HGG68_RS23350	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS23355	COG1129	ABC transporter
HGG68_RS23360	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS23365	COG1737	Transcriptional regulator
HGG68_RS23370	COG0698	ribose 5-phosphate isomerase
HGG68_RS23380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HGG68_RS23385	COG0456	acetyltransferase
HGG68_RS23395	COG3454	Phosphonate metabolism
HGG68_RS23400	COG4778	phosphonate C-P lyase system protein PhnL
HGG68_RS23405	COG4107	phosphonate C-P lyase system protein PhnK
HGG68_RS23410	COG3627	carbon phosphorus lyase activity
HGG68_RS23415	COG3626	phosphonate metabolism
HGG68_RS23420	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HGG68_RS23425	COG3624	Phosphonate C-P lyase system protein PhnG
HGG68_RS23430	COG2188	Transcriptional regulator
HGG68_RS23435	COG3639	organic phosphonate transmembrane transporter activity
HGG68_RS23440	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HGG68_RS23445	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HGG68_RS23450	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HGG68_RS23455	COG2824	Alkylphosphonate utilization operon protein PhnA
HGG68_RS23470	COG0477	Major facilitator Superfamily
HGG68_RS23480	COG0642	Histidine kinase
HGG68_RS23485	COG0745	RESPONSE REGULATOR receiver
HGG68_RS23490	COG2194	sulfuric ester hydrolase activity
HGG68_RS23495	COG0531	amino acid
HGG68_RS23500	COG2207	Transcriptional regulator
HGG68_RS23505	COG1982	Orn Lys Arg decarboxylase major
HGG68_RS23510	COG2169	Transcriptional regulator
HGG68_RS23515	COG1486	melibiose metabolic process
HGG68_RS23525	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HGG68_RS23525	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HGG68_RS23530	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HGG68_RS23535	COG4565	transcriptional regulatory protein
HGG68_RS23540	COG3290	protein histidine kinase activity
HGG68_RS23545	COG3592	Divergent 4Fe-4S mono-cluster
HGG68_RS23550	COG2388	GCN5-related N-acetyl-transferase
HGG68_RS23565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HGG68_RS23570	COG3104	oligopeptide transport
HGG68_RS23575	COG1982	Orn Lys Arg decarboxylase major
HGG68_RS23580	COG0531	amino acid
HGG68_RS23585	COG3710	Transcriptional regulator
HGG68_RS23595	COG4584	PFAM Integrase catalytic
HGG68_RS23600	COG1484	DNA-dependent DNA replication
HGG68_RS23635	COG2003	Belongs to the UPF0758 family
HGG68_RS23660	COG2378	regulation of single-species biofilm formation
HGG68_RS23665	COG3596	GTP binding
HGG68_RS23695	COG4771	TonB-dependent receptor
HGG68_RS23840	COG3969	phosphoadenosine phosphosulfate
HGG68_RS23865	COG0582	viral genome integration into host DNA
HGG68_RS23875	COG1309	transcriptional regulator
HGG68_RS23880	COG4232	protein-disulfide reductase activity
HGG68_RS23890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HGG68_RS23895	COG1027	Aspartate ammonia-lyase
HGG68_RS23900	COG3030	protein affecting phage T7 exclusion by the F plasmid
HGG68_RS23905	COG0531	amino acid
HGG68_RS23930	COG1509	lysine 2,3-aminomutase activity
HGG68_RS23940	COG5510	response to toxic substance
HGG68_RS23945	COG5510	response to toxic substance
HGG68_RS23950	COG2076	Multidrug Resistance protein
HGG68_RS23955	COG3040	lipid binding
HGG68_RS23960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HGG68_RS23975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HGG68_RS23980	COG1053	succinate dehydrogenase
HGG68_RS23990	COG0531	amino acid
HGG68_RS23995	COG3264	Mechanosensitive ion channel
HGG68_RS23995	COG1511	domain protein
HGG68_RS24035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HGG68_RS24040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGG68_RS24040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HGG68_RS24045	COG0802	atpase or kinase
HGG68_RS24050	COG0860	N-Acetylmuramoyl-L-alanine amidase
HGG68_RS24055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGG68_RS24070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGG68_RS24075	COG0330	HflC and HflK could
HGG68_RS24080	COG0330	HflC and HflK could
HGG68_RS24085	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HGG68_RS24100	COG0557	exoribonuclease II activity
HGG68_RS24105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGG68_RS24110	COG3789	protein conserved in bacteria
HGG68_RS24115	COG1842	Phage shock protein A
HGG68_RS24125	COG3766	membrane
HGG68_RS24130	COG5463	Belongs to the UPF0441 family
HGG68_RS24135	COG0754	glutathionylspermidine amidase activity
HGG68_RS24140	COG1960	acyl-CoA dehydrogenase activity
HGG68_RS24150	COG3650	response to hydrogen peroxide
HGG68_RS24155	COG1073	alpha beta
HGG68_RS24170	COG3037	sugar-specific permease SgaT UlaA
HGG68_RS24180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HGG68_RS24195	COG0235	Class ii aldolase
HGG68_RS24215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGG68_RS24235	COG2271	Major facilitator Superfamily
HGG68_RS24240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HGG68_RS24245	COG4670	ketone body catabolic process
HGG68_RS24250	COG1024	Enoyl-CoA hydratase
HGG68_RS24265	COG1309	transcriptional regulator
HGG68_RS24270	COG3061	Opacity-associated protein A
HGG68_RS24275	COG0545	Peptidyl-prolyl cis-trans isomerase
HGG68_RS24280	COG1113	amino acid transport
HGG68_RS24295	COG0702	epimerase
HGG68_RS24300	COG1733	regulation of RNA biosynthetic process
HGG68_RS24305	COG0737	Belongs to the 5'-nucleotidase family
HGG68_RS24310	COG1218	3'(2'),5'-bisphosphate nucleotidase
HGG68_RS24315	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HGG68_RS24325	COG1253	flavin adenine dinucleotide binding
HGG68_RS24330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGG68_RS24335	COG0729	surface antigen
HGG68_RS24340	COG2911	Protein conserved in bacteria
HGG68_RS24345	COG2105	PFAM AIG2 family protein
HGG68_RS24350	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HGG68_RS24355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HGG68_RS24360	COG1879	ABC-type sugar transport system periplasmic component
HGG68_RS24365	COG1129	ABC transporter
HGG68_RS24370	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS24375	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGG68_RS24385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HGG68_RS24390	COG3028	Belongs to the UPF0307 family
HGG68_RS24395	COG0312	modulator of DNA gyrase
HGG68_RS24400	COG3783	Cytochrome b(562)
HGG68_RS24405	COG0602	queuosine metabolic process
HGG68_RS24410	COG1328	CTP reductase activity
HGG68_RS24415	COG0366	Alpha amylase catalytic
HGG68_RS24420	COG1263	PTS System
HGG68_RS24420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HGG68_RS24425	COG1609	Transcriptional regulator
HGG68_RS24435	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HGG68_RS24440	COG0251	oxidation-reduction process
HGG68_RS24460	COG1438	arginine binding
HGG68_RS24465	COG1288	antiporter activity
HGG68_RS24470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGG68_RS24475	COG0549	Belongs to the carbamate kinase family
HGG68_RS24485	COG2731	YhcH YjgK YiaL family protein
HGG68_RS24490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGG68_RS24495	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HGG68_RS24500	COG0456	acetyltransferase
HGG68_RS24510	COG0525	valine-tRNA ligase activity
HGG68_RS24515	COG2927	DNA polymerase III (CHI subunit)
HGG68_RS24525	COG0795	lipopolysaccharide-transporting ATPase activity
HGG68_RS24530	COG0795	lipopolysaccharide-transporting ATPase activity
HGG68_RS24535	COG0433	COG0433 Predicted ATPase
HGG68_RS24540	COG1609	Transcriptional regulator
HGG68_RS24545	COG2610	gluconate transmembrane transporter activity
HGG68_RS24550	COG1028	Short-chain dehydrogenase reductase Sdr
HGG68_RS24555	COG1063	alcohol dehydrogenase
HGG68_RS24560	COG3265	gluconokinase activity
HGG68_RS24565	COG1064	alcohol dehydrogenase
HGG68_RS24575	COG0582	viral genome integration into host DNA
HGG68_RS24645	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HGG68_RS24650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HGG68_RS24655	COG0582	viral genome integration into host DNA
HGG68_RS24660	COG4974	Belongs to the 'phage' integrase family
HGG68_RS24665	COG3539	Fimbrial protein
HGG68_RS24670	COG3539	Fimbrial protein
HGG68_RS24675	COG3121	Chaperone
HGG68_RS24680	COG3188	usher protein
HGG68_RS24685	COG3539	Fimbrial protein
HGG68_RS24690	COG3539	Fimbrial protein
HGG68_RS24695	COG3539	Fimbrial protein
HGG68_RS24700	COG2610	gluconate transmembrane transporter activity
HGG68_RS24710	COG0246	Mannitol dehydrogenase
HGG68_RS24715	COG2186	Transcriptional regulator
HGG68_RS24720	COG3518	anti-sigma factor antagonist activity
HGG68_RS24730	COG0583	DNA-binding transcription factor activity
HGG68_RS24735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGG68_RS24740	COG0700	Nucleoside recognition
HGG68_RS24745	COG3366	ferrous iron transmembrane transporter activity
HGG68_RS24755	COG0477	Major facilitator Superfamily
HGG68_RS24770	COG1924	4 iron, 4 sulfur cluster binding
HGG68_RS24775	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HGG68_RS24780	COG2733	membrane
HGG68_RS24790	COG5457	Domain of unknown function (DUF1127)
HGG68_RS24805	COG0732	type I restriction modification DNA specificity domain
HGG68_RS24825	COG0523	cobalamin synthesis protein
HGG68_RS24830	COG2879	small protein
HGG68_RS24835	COG1966	Carbon starvation protein
HGG68_RS24840	COG0840	transmembrane signaling receptor activity
HGG68_RS24855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HGG68_RS24860	COG0025	NhaP-type Na H and K H
HGG68_RS24865	COG1802	Transcriptional regulator
HGG68_RS24870	COG1063	alcohol dehydrogenase
HGG68_RS24875	COG1368	sulfuric ester hydrolase activity
HGG68_RS24885	COG1484	DNA-dependent DNA replication
HGG68_RS24900	COG2966	Psort location CytoplasmicMembrane, score
HGG68_RS24905	COG2197	response regulator
HGG68_RS24910	COG2197	response regulator
HGG68_RS24915	COG4114	ferric iron reductase
HGG68_RS24940	COG2813	Specifically methylates the guanine in position
HGG68_RS24945	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HGG68_RS24950	COG0456	acetyltransferase
HGG68_RS24955	COG1011	Hydrolase
HGG68_RS24965	COG2823	Periplasmic or secreted lipoprotein
HGG68_RS24975	COG4667	esterase of the alpha-beta hydrolase superfamily
HGG68_RS24980	COG0084	hydrolase, TatD family'
HGG68_RS24985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGG68_RS24990	COG1328	CTP reductase activity
HGG68_RS25020	COG3550	peptidyl-serine autophosphorylation
HGG68_RS25025	COG0095	Lipoate-protein ligase
HGG68_RS25030	COG3726	membrane protein affecting hemolysin expression
HGG68_RS25035	COG0560	Phosphoserine phosphatase
HGG68_RS25040	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGG68_RS25045	COG1056	cytidyltransferase-related domain
HGG68_RS25045	COG3172	ATPase kinase involved in NAD metabolism
HGG68_RS25050	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HGG68_RS25060	COG0488	(ABC) transporter
HGG68_RS25065	COG0741	lytic transglycosylase activity
HGG68_RS25085	COG3708	Transcriptional regulator
HGG68_RS25085	COG2207	Transcriptional regulator
HGG68_RS25090	COG3045	CreA protein
HGG68_RS25095	COG0745	RESPONSE REGULATOR receiver
HGG68_RS25100	COG2205	protein histidine kinase activity
HGG68_RS25105	COG4452	Inner membrane protein CreD
HGG68_RS25110	COG0745	RESPONSE REGULATOR receiver
HGG68_RS25120	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA