locus-tag	class	description
EAH50_RS00065	COG3121	Chaperone
EAH50_RS00070	COG3539	Fimbrial protein
EAH50_RS00080	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAH50_RS00105	COG2026	Addiction module toxin, RelE StbE family
EAH50_RS00150	COG1192	Involved in chromosome partitioning
EAH50_RS00200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EAH50_RS00315	COG0616	signal peptide processing
EAH50_RS00385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAH50_RS00465	COG2801	Transposase and inactivated derivatives
EAH50_RS00470	COG2186	Transcriptional regulator
EAH50_RS00480	COG0246	Mannitol dehydrogenase
EAH50_RS00490	COG2271	Major facilitator Superfamily
EAH50_RS00595	COG3173	Aminoglycoside phosphotransferase
EAH50_RS00675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAH50_RS00680	COG2194	sulfuric ester hydrolase activity
EAH50_RS00700	COG1660	Displays ATPase and GTPase activities
EAH50_RS00745	COG2826	transposase and inactivated derivatives, IS30 family
EAH50_RS00760	COG2826	transposase and inactivated derivatives, IS30 family
EAH50_RS00860	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EAH50_RS00930	COG0445	tRNA wobble uridine modification
EAH50_RS00965	COG1192	Involved in chromosome partitioning
EAH50_RS01060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAH50_RS01065	COG2313	pseudouridylate synthase activity
EAH50_RS01070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS01090	COG0210	DNA helicase
EAH50_RS01485	COG3300	MHYT domain
EAH50_RS01485	COG5001	Diguanylate cyclase
EAH50_RS01520	COG4221	oxidoreductase activity
EAH50_RS01620	COG3039	Transposase
EAH50_RS01675	COG0697	spore germination
EAH50_RS01725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAH50_RS01845	COG4221	oxidoreductase activity
EAH50_RS01875	COG1660	Displays ATPase and GTPase activities
EAH50_RS01950	COG2186	Transcriptional regulator
EAH50_RS01955	COG2186	Transcriptional regulator
EAH50_RS02050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EAH50_RS02055	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EAH50_RS02075	COG3039	Transposase
EAH50_RS02085	COG4974	Belongs to the 'phage' integrase family
EAH50_RS02090	COG3385	transposase activity
EAH50_RS02145	COG0592	DNA-directed DNA polymerase activity
EAH50_RS02155	COG0187	DNA topoisomerase II activity
EAH50_RS02165	COG0561	phosphatase activity
EAH50_RS02175	COG2186	Transcriptional regulator
EAH50_RS02180	COG3734	2-keto-3-deoxy-galactonokinase
EAH50_RS02185	COG0800	Aldolase
EAH50_RS02195	COG2271	Major facilitator Superfamily
EAH50_RS02205	COG0823	Involved in the tonB-independent uptake of proteins
EAH50_RS02210	COG5645	(Lipo)protein
EAH50_RS02230	COG2188	Transcriptional regulator
EAH50_RS02245	COG2207	Transcriptional regulator
EAH50_RS02250	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAH50_RS02255	COG3119	arylsulfatase activity
EAH50_RS02265	COG2149	membrane
EAH50_RS02275	COG0641	radical SAM
EAH50_RS02280	COG2814	Major facilitator Superfamily
EAH50_RS02295	COG0028	Belongs to the TPP enzyme family
EAH50_RS02300	COG0440	acetolactate synthase activity
EAH50_RS02305	COG2197	response regulator
EAH50_RS02310	COG3851	Histidine kinase
EAH50_RS02315	COG2271	Major facilitator Superfamily
EAH50_RS02320	COG2271	Major facilitator Superfamily
EAH50_RS02330	COG2252	PERMEase
EAH50_RS02350	COG1464	Belongs to the NlpA lipoprotein family
EAH50_RS02355	COG0697	spore germination
EAH50_RS02380	COG2211	Major facilitator Superfamily
EAH50_RS02385	COG1501	Belongs to the glycosyl hydrolase 31 family
EAH50_RS02390	COG2982	Protein involved in outer membrane biogenesis
EAH50_RS02395	COG2233	PERMEase
EAH50_RS02400	COG0786	glutamate:sodium symporter activity
EAH50_RS02405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAH50_RS02410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAH50_RS02415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAH50_RS02425	COG0194	GDP metabolic process
EAH50_RS02435	COG2860	membrane
EAH50_RS02440	COG3645	SOS response
EAH50_RS02445	COG1561	YicC-like family, N-terminal region
EAH50_RS02470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAH50_RS02500	COG1519	Transferase
EAH50_RS02505	COG0859	PFAM glycosyl transferase family 9
EAH50_RS02510	COG0438	transferase activity, transferring glycosyl groups
EAH50_RS02515	COG0515	serine threonine protein kinase
EAH50_RS02525	COG3642	lipopolysaccharide core region biosynthetic process
EAH50_RS02545	COG0859	PFAM glycosyl transferase family 9
EAH50_RS02550	COG0859	PFAM glycosyl transferase family 9
EAH50_RS02570	COG0156	8-amino-7-oxononanoate synthase activity
EAH50_RS02580	COG1216	Glycosyl transferase, family 2
EAH50_RS02585	COG2861	carbohydrate metabolic process
EAH50_RS02590	COG4942	peptidase
EAH50_RS02595	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAH50_RS02605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAH50_RS02610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAH50_RS02625	COG1045	serine acetyltransferase
EAH50_RS02630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAH50_RS02640	COG2186	Transcriptional regulator
EAH50_RS02645	COG1620	l-lactate permease
EAH50_RS02660	COG3722	fumarate hydratase activity
EAH50_RS02670	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS02670	COG2213	PTS system mannitol-specific
EAH50_RS02680	COG1566	PFAM secretion protein HlyD family protein
EAH50_RS02700	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAH50_RS02710	COG1413	lyase activity
EAH50_RS02720	COG0625	glutathione transferase activity
EAH50_RS02730	COG3276	selenocysteine insertion sequence binding
EAH50_RS02735	COG1454	alcohol dehydrogenase
EAH50_RS02740	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS02755	COG1566	PFAM secretion protein HlyD family protein
EAH50_RS02760	COG0583	DNA-binding transcription factor activity
EAH50_RS02765	COG3713	MltA-interacting MipA family protein
EAH50_RS02775	COG0235	Class ii aldolase
EAH50_RS02780	COG3623	hexulose-6-phosphate isomerase
EAH50_RS02785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EAH50_RS02790	COG1070	Carbohydrate kinase
EAH50_RS02795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAH50_RS02800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAH50_RS02805	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAH50_RS02810	COG2731	YhcH YjgK YiaL family protein
EAH50_RS02820	COG1414	Transcriptional regulator
EAH50_RS02825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS02830	COG3977	Valine--pyruvate aminotransferase
EAH50_RS02835	COG0366	Alpha amylase catalytic
EAH50_RS02840	COG2992	FlgJ-related protein
EAH50_RS02845	COG2207	Transcriptional regulator
EAH50_RS02845	COG1609	Transcriptional regulator
EAH50_RS02850	COG4214	carbohydrate transport
EAH50_RS02855	COG1129	ABC transporter
EAH50_RS02860	COG4213	ABC transporter substrate-binding protein
EAH50_RS02870	COG1070	Carbohydrate kinase
EAH50_RS02875	COG4682	membrane
EAH50_RS02880	COG4682	membrane
EAH50_RS02885	COG3274	enterobacterial common antigen metabolic process
EAH50_RS02915	COG1278	Cold shock
EAH50_RS02920	COG2944	sequence-specific DNA binding
EAH50_RS02935	COG2885	chlorophyll binding
EAH50_RS02940	COG0243	molybdopterin cofactor binding
EAH50_RS02945	COG0456	acetyltransferase
EAH50_RS02950	COG2818	Glycosylase
EAH50_RS02955	COG5571	outer membrane autotransporter
EAH50_RS02960	COG2223	nitrite transmembrane transporter activity
EAH50_RS02965	COG2194	sulfuric ester hydrolase activity
EAH50_RS02975	COG0747	negative chemotaxis
EAH50_RS02980	COG0601	transmembrane transport
EAH50_RS02985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAH50_RS02990	COG0444	Belongs to the ABC transporter superfamily
EAH50_RS02995	COG4608	Belongs to the ABC transporter superfamily
EAH50_RS03000	COG0814	amino acid
EAH50_RS03010	COG2194	sulfuric ester hydrolase activity
EAH50_RS03035	COG1215	transferase activity, transferring glycosyl groups
EAH50_RS03040	COG1215	transferase activity, transferring glycosyl groups
EAH50_RS03045	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EAH50_RS03050	COG0457	Tetratricopeptide repeat
EAH50_RS03050	COG3118	belongs to the thioredoxin family
EAH50_RS03055	COG2200	EAL domain
EAH50_RS03055	COG2199	diguanylate cyclase activity
EAH50_RS03065	COG0612	Peptidase, M16
EAH50_RS03070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS03075	COG2200	EAL domain
EAH50_RS03080	COG2982	Protein involved in outer membrane biogenesis
EAH50_RS03085	COG0477	Major facilitator Superfamily
EAH50_RS03090	COG1295	ribonuclease BN
EAH50_RS03095	COG0583	DNA-binding transcription factor activity
EAH50_RS03100	COG2197	response regulator
EAH50_RS03110	COG1858	cytochrome C peroxidase
EAH50_RS03115	COG0076	glutamate decarboxylase activity
EAH50_RS03120	COG2207	Transcriptional regulator
EAH50_RS03125	COG2207	Transcriptional regulator
EAH50_RS03130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAH50_RS03135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS03145	COG2771	luxR family
EAH50_RS03150	COG3247	response to pH
EAH50_RS03165	COG1285	pathogenesis
EAH50_RS03170	COG2197	response regulator
EAH50_RS03175	COG3065	identical protein binding
EAH50_RS03195	COG1393	Belongs to the ArsC family
EAH50_RS03200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EAH50_RS03205	COG0640	Transcriptional regulator
EAH50_RS03215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAH50_RS03220	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAH50_RS03225	COG0339	signal peptide processing
EAH50_RS03235	COG3104	oligopeptide transport
EAH50_RS03245	COG0589	response to stress
EAH50_RS03255	COG0306	phosphate transporter
EAH50_RS03260	COG2081	HI0933 family
EAH50_RS03335	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS03365	COG0739	heme binding
EAH50_RS03375	COG2132	Multicopper oxidase
EAH50_RS03380	COG3667	copper resistance
EAH50_RS03385	COG2372	response to copper ion
EAH50_RS03390	COG1276	copper resistance
EAH50_RS03395	COG0745	RESPONSE REGULATOR receiver
EAH50_RS03400	COG2205	protein histidine kinase activity
EAH50_RS03430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS03435	COG1129	ABC transporter
EAH50_RS03435	COG0842	Transport permease protein
EAH50_RS03440	COG0842	Transport permease protein
EAH50_RS03450	COG1413	lyase activity
EAH50_RS03470	COG1124	(ABC) transporter
EAH50_RS03475	COG0444	Belongs to the ABC transporter superfamily
EAH50_RS03480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAH50_RS03485	COG0601	transmembrane transport
EAH50_RS03490	COG0747	negative chemotaxis
EAH50_RS03495	COG2091	lysine biosynthetic process via aminoadipic acid
EAH50_RS03500	COG0628	permease
EAH50_RS03505	COG0477	Major facilitator Superfamily
EAH50_RS03515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EAH50_RS03530	COG3714	YhhN family
EAH50_RS03540	COG3776	membrane
EAH50_RS03545	COG0742	ribosomal rna small subunit methyltransferase
EAH50_RS03550	COG0552	protein localization to endoplasmic reticulum
EAH50_RS03555	COG2884	Cell division ATP-binding protein ftsE
EAH50_RS03560	COG2177	Part of the ABC transporter FtsEX involved in
EAH50_RS03565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAH50_RS03570	COG0683	leucine binding
EAH50_RS03575	COG0456	acetyltransferase
EAH50_RS03580	COG0683	leucine binding
EAH50_RS03585	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS03590	COG4177	L-phenylalanine transmembrane transporter activity
EAH50_RS03595	COG0411	ABC transporter
EAH50_RS03600	COG0410	ABC transporter
EAH50_RS03605	COG1653	transport
EAH50_RS03610	COG1175	transmembrane transport
EAH50_RS03615	COG0395	ABC-type sugar transport system, permease component
EAH50_RS03625	COG0584	glycerophosphoryl diester phosphodiesterase
EAH50_RS03635	COG0405	Gamma-glutamyltransferase
EAH50_RS03655	COG3157	Type VI secretion system effector, Hcp
EAH50_RS03660	COG1247	-acetyltransferase
EAH50_RS03665	COG0673	inositol 2-dehydrogenase activity
EAH50_RS03670	COG1741	Belongs to the pirin family
EAH50_RS03675	COG1609	Transcriptional regulator
EAH50_RS03680	COG3265	gluconokinase activity
EAH50_RS03685	COG2610	gluconate transmembrane transporter activity
EAH50_RS03690	COG2095	MarC family integral membrane protein
EAH50_RS03695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAH50_RS03720	COG0058	SHG alpha-glucan phosphorylase activity
EAH50_RS03730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAH50_RS03745	COG1349	DNA-binding transcription factor activity
EAH50_RS03750	COG4650	regulator
EAH50_RS03755	COG1690	Belongs to the RtcB family
EAH50_RS03770	COG0058	SHG alpha-glucan phosphorylase activity
EAH50_RS03775	COG1640	4-alpha-glucanotransferase
EAH50_RS03780	COG2610	gluconate transmembrane transporter activity
EAH50_RS03790	COG1040	competence protein
EAH50_RS03800	COG5464	transposase or invertase
EAH50_RS03810	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EAH50_RS03815	COG1918	ferrous iron import across plasma membrane
EAH50_RS03820	COG2183	response to ionizing radiation
EAH50_RS03825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAH50_RS03845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EAH50_RS03855	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAH50_RS03860	COG1011	Hydrolase
EAH50_RS03870	COG0494	nUDIX hydrolase
EAH50_RS03875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EAH50_RS03880	COG4972	Pilus assembly protein
EAH50_RS03885	COG3166	PFAM Fimbrial assembly family protein
EAH50_RS03900	COG4796	Type ii and iii secretion system protein
EAH50_RS03915	COG3266	domain, Protein
EAH50_RS03920	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EAH50_RS03925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAH50_RS03930	COG0546	phosphoglycolate phosphatase activity
EAH50_RS03935	COG0180	Tryptophanyl-tRNA synthetase
EAH50_RS03945	COG2188	Transcriptional regulator
EAH50_RS03955	COG3457	Alanine racemase
EAH50_RS03960	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EAH50_RS03965	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EAH50_RS03980	COG0626	cystathionine gamma-synthase activity
EAH50_RS03985	COG2188	Transcriptional regulator
EAH50_RS03990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS03995	COG1082	Xylose isomerase domain protein TIM barrel
EAH50_RS04000	COG2222	sugar isomerase
EAH50_RS04005	COG0531	amino acid
EAH50_RS04020	COG2116	formate transmembrane transporter activity
EAH50_RS04025	COG2146	nitrite reductase [NAD(P)H] activity
EAH50_RS04030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAH50_RS04040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAH50_RS04050	COG2184	nucleotidyltransferase activity
EAH50_RS04055	COG0512	Glutamine amidotransferase of anthranilate synthase
EAH50_RS04060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAH50_RS04065	COG1289	transmembrane transporter activity
EAH50_RS04070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAH50_RS04075	COG1765	OsmC-like protein
EAH50_RS04080	COG3954	Phosphoribulokinase
EAH50_RS04090	COG0429	hydrolase of the alpha beta-hydrolase fold
EAH50_RS04095	COG0488	(ABC) transporter
EAH50_RS04110	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EAH50_RS04115	COG1047	Peptidyl-prolyl cis-trans
EAH50_RS04125	COG0545	Peptidyl-prolyl cis-trans isomerase
EAH50_RS04130	COG2964	Protein conserved in bacteria
EAH50_RS04170	COG3979	chitinase
EAH50_RS04175	COG2906	2 iron, 2 sulfur cluster binding
EAH50_RS04180	COG2193	ferroxidase activity
EAH50_RS04185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EAH50_RS04190	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EAH50_RS04195	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EAH50_RS04200	COG3156	type II secretion system protein K
EAH50_RS04205	COG4795	General secretion pathway protein
EAH50_RS04210	COG2165	general secretion pathway protein
EAH50_RS04215	COG2165	general secretion pathway protein
EAH50_RS04220	COG2165	general secretion pathway protein
EAH50_RS04225	COG1459	type II secretion system
EAH50_RS04230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAH50_RS04235	COG1450	Type ii and iii secretion system protein
EAH50_RS04240	COG3031	protein transport across the cell outer membrane
EAH50_RS04245	COG3267	Type II secretory pathway component ExeA
EAH50_RS04245	COG3409	Peptidoglycan-binding domain 1 protein
EAH50_RS04270	COG0089	rRNA binding
EAH50_RS04360	COG0201	protein transport
EAH50_RS04400	COG0789	Transcriptional regulator
EAH50_RS04405	COG3036	rescue of stalled ribosome
EAH50_RS04415	COG0569	domain protein
EAH50_RS04435	COG0758	DNA mediated transformation
EAH50_RS04445	COG0551	DNA topoisomerase type I activity
EAH50_RS04465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAH50_RS04505	COG1126	abc transporter atp-binding protein
EAH50_RS04510	COG0765	amino acid transport
EAH50_RS04515	COG4597	amino acid ABC transporter
EAH50_RS04520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS04530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAH50_RS04535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS04540	COG1309	transcriptional regulator
EAH50_RS04550	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EAH50_RS04560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAH50_RS04570	COG4145	pantothenate transmembrane transporter activity
EAH50_RS04575	COG3924	membrane
EAH50_RS04580	COG0439	Biotin carboxylase
EAH50_RS04585	COG0511	ligase activity, forming carbon-carbon bonds
EAH50_RS04590	COG0604	alcohol dehydrogenase
EAH50_RS04595	COG2199	diguanylate cyclase activity
EAH50_RS04595	COG2200	EAL domain
EAH50_RS04605	COG1077	Cell shape determining protein MreB Mrl
EAH50_RS04610	COG1792	Involved in formation and maintenance of cell shape
EAH50_RS04615	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EAH50_RS04625	COG1530	ribonuclease E activity
EAH50_RS04630	COG3164	Protein of unknown function
EAH50_RS04635	COG0312	modulator of DNA gyrase
EAH50_RS04640	COG0583	DNA-binding transcription factor activity
EAH50_RS04660	COG2732	(Barnase) inhibitor
EAH50_RS04680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAH50_RS04685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAH50_RS04690	COG3105	Protein conserved in bacteria
EAH50_RS04695	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAH50_RS04710	COG0625	glutathione transferase activity
EAH50_RS04715	COG2969	positive regulation of protein catabolic process
EAH50_RS04720	COG3069	C4-dicarboxylate transmembrane transporter activity
EAH50_RS04750	COG2731	YhcH YjgK YiaL family protein
EAH50_RS04755	COG4804	nuclease activity
EAH50_RS04760	COG3539	Fimbrial protein
EAH50_RS04770	COG3188	usher protein
EAH50_RS04775	COG3121	Chaperone
EAH50_RS04795	COG0493	'glutamate synthase
EAH50_RS04800	COG0069	glutamate synthase activity
EAH50_RS04800	COG0070	glutamate synthase
EAH50_RS04800	COG0067	glutamate synthase
EAH50_RS04805	COG1242	4 iron, 4 sulfur cluster binding
EAH50_RS04810	COG0784	Response regulator, receiver
EAH50_RS04810	COG2198	Histidine kinase
EAH50_RS04810	COG5002	protein histidine kinase activity
EAH50_RS04815	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EAH50_RS04825	COG0515	serine threonine protein kinase
EAH50_RS04830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS04845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAH50_RS04850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EAH50_RS04855	COG1137	ATPase activity
EAH50_RS04860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EAH50_RS04865	COG3117	lipopolysaccharide transmembrane transporter activity
EAH50_RS04870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAH50_RS04875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAH50_RS04875	COG0517	IMP dehydrogenase activity
EAH50_RS04880	COG0530	calcium, potassium:sodium antiporter activity
EAH50_RS04885	COG1127	ABC transporter
EAH50_RS04890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAH50_RS04895	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAH50_RS04900	COG2854	intermembrane phospholipid transfer
EAH50_RS04905	COG3113	response to antibiotic
EAH50_RS04910	COG5007	Belongs to the BolA IbaG family
EAH50_RS04920	COG3423	Transcriptional regulator
EAH50_RS04925	COG0142	geranyltranstransferase activity
EAH50_RS04940	COG0697	spore germination
EAH50_RS04950	COG2027	D-alanyl-D-alanine carboxypeptidase
EAH50_RS04955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAH50_RS04960	COG1534	Rna-binding protein
EAH50_RS04970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAH50_RS04975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EAH50_RS04985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAH50_RS04995	COG2194	sulfuric ester hydrolase activity
EAH50_RS05015	COG0195	Participates in both transcription termination and antitermination
EAH50_RS05055	COG0513	Belongs to the DEAD box helicase family
EAH50_RS05060	COG0814	amino acid
EAH50_RS05065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAH50_RS05070	COG0826	peptidase U32
EAH50_RS05075	COG0826	peptidase U32
EAH50_RS05080	COG3154	lipid carrier protein
EAH50_RS05085	COG3153	acetyltransferase
EAH50_RS05100	COG0693	protein deglycase activity
EAH50_RS05105	COG0702	epimerase
EAH50_RS05110	COG0701	Predicted permease
EAH50_RS05115	COG2823	Periplasmic or secreted lipoprotein
EAH50_RS05130	COG3107	peptidoglycan biosynthetic process
EAH50_RS05135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAH50_RS05140	COG3539	Fimbrial protein
EAH50_RS05145	COG3188	usher protein
EAH50_RS05150	COG3121	Chaperone
EAH50_RS05155	COG3539	Fimbrial protein
EAH50_RS05160	COG0363	glucosamine-6-phosphate deaminase activity
EAH50_RS05165	COG3716	PTS system mannose fructose sorbose family IID component
EAH50_RS05170	COG3715	PTS system
EAH50_RS05175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS05185	COG2222	sugar isomerase
EAH50_RS05190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAH50_RS05195	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS05200	COG3716	PTS system mannose fructose sorbose family IID component
EAH50_RS05210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS05220	COG1349	DNA-binding transcription factor activity
EAH50_RS05230	COG2002	toxin-antitoxin pair type II binding
EAH50_RS05235	COG2721	sulfolactate sulfo-lyase activity
EAH50_RS05240	COG2271	Major facilitator Superfamily
EAH50_RS05250	COG2084	Dehydrogenase
EAH50_RS05255	COG1929	Belongs to the glycerate kinase type-1 family
EAH50_RS05280	COG0583	DNA-binding transcription factor activity
EAH50_RS05285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAH50_RS05295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAH50_RS05300	COG1882	Formate acetyltransferase
EAH50_RS05305	COG0251	oxidation-reduction process
EAH50_RS05310	COG1760	l-serine dehydratase
EAH50_RS05315	COG0814	amino acid
EAH50_RS05330	COG1741	Belongs to the pirin family
EAH50_RS05335	COG0583	DNA-binding transcription factor activity
EAH50_RS05340	COG3152	Membrane
EAH50_RS05345	COG3152	Membrane
EAH50_RS05350	COG0435	Glutathione S-transferase
EAH50_RS05355	COG2259	Doxx family
EAH50_RS05365	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EAH50_RS05370	COG4575	ribosome binding
EAH50_RS05375	COG1422	Protein of unknown function (DUF1090)
EAH50_RS05385	COG0586	Pfam SNARE associated Golgi protein
EAH50_RS05390	COG2186	Transcriptional regulator
EAH50_RS05395	COG2271	Major facilitator Superfamily
EAH50_RS05405	COG2721	sulfolactate sulfo-lyase activity
EAH50_RS05415	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EAH50_RS05420	COG0861	Integral membrane protein TerC family
EAH50_RS05425	COG0673	inositol 2-dehydrogenase activity
EAH50_RS05430	COG2949	membrane
EAH50_RS05435	COG1451	nucleotide metabolic process
EAH50_RS05445	COG4680	protein conserved in bacteria
EAH50_RS05450	COG5499	transcription regulator containing HTH domain
EAH50_RS05455	COG1902	pentaerythritol trinitrate reductase activity
EAH50_RS05455	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAH50_RS05460	COG3408	Glycogen debranching enzyme
EAH50_RS05460	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EAH50_RS05470	COG0531	amino acid
EAH50_RS05475	COG2731	YhcH YjgK YiaL family protein
EAH50_RS05480	COG3250	beta-galactosidase activity
EAH50_RS05485	COG1609	Transcriptional regulator
EAH50_RS05490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAH50_RS05500	COG0840	transmembrane signaling receptor activity
EAH50_RS05505	COG1695	Transcriptional regulator
EAH50_RS05510	COG2375	cellular response to nickel ion
EAH50_RS05525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAH50_RS05530	COG0358	DNA primase activity
EAH50_RS05535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EAH50_RS05545	COG0471	metal ion transport
EAH50_RS05550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAH50_RS05555	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAH50_RS05560	COG0583	DNA-binding transcription factor activity
EAH50_RS05570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAH50_RS05585	COG4991	sh3 domain protein
EAH50_RS05590	COG3025	triphosphatase activity
EAH50_RS05615	COG2268	Band 7 protein
EAH50_RS05620	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAH50_RS05630	COG3539	Fimbrial protein
EAH50_RS05635	COG3121	Chaperone
EAH50_RS05640	COG3188	usher protein
EAH50_RS05645	COG3539	Fimbrial protein
EAH50_RS05650	COG2960	long-chain fatty acid transporting porin activity
EAH50_RS05665	COG3384	dioxygenase
EAH50_RS05670	COG0754	glutathionylspermidine amidase activity
EAH50_RS05680	COG1538	Outer membrane efflux protein
EAH50_RS05685	COG0494	nUDIX hydrolase
EAH50_RS05690	COG3151	Protein conserved in bacteria
EAH50_RS05695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAH50_RS05700	COG3150	esterase
EAH50_RS05705	COG0187	DNA topoisomerase II activity
EAH50_RS05710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EAH50_RS05715	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAH50_RS05725	COG0642	Histidine kinase
EAH50_RS05730	COG0745	RESPONSE REGULATOR receiver
EAH50_RS05735	COG3111	PFAM Bacterial OB fold (BOF) protein
EAH50_RS05755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EAH50_RS05765	COG2944	sequence-specific DNA binding
EAH50_RS05770	COG4166	transmembrane transport
EAH50_RS05775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAH50_RS05780	COG0204	Acyl-transferase
EAH50_RS05785	COG2132	Multicopper oxidase
EAH50_RS05790	COG1032	radical SAM domain protein
EAH50_RS05795	COG4238	major outer membrane lipoprotein
EAH50_RS05805	COG0656	L-ascorbic acid biosynthetic process
EAH50_RS05810	COG1979	alcohol dehydrogenase
EAH50_RS05815	COG2207	Transcriptional regulator
EAH50_RS05820	COG0586	Pfam SNARE associated Golgi protein
EAH50_RS05825	COG0626	cystathionine gamma-synthase activity
EAH50_RS05830	COG0811	peptide transport
EAH50_RS05835	COG0848	biopolymer transport protein
EAH50_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS05850	COG0667	Aldo Keto reductase
EAH50_RS05865	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EAH50_RS05870	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS05875	COG5557	Pfam Polysulphide reductase, NrfD
EAH50_RS05880	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EAH50_RS05885	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EAH50_RS05890	COG1773	rubredoxin
EAH50_RS05900	COG0298	carbon dioxide binding
EAH50_RS05905	COG0625	glutathione transferase activity
EAH50_RS05910	COG0754	glutathionylspermidine amidase activity
EAH50_RS05935	COG2200	EAL domain
EAH50_RS05975	COG5433	transposase activity
EAH50_RS06010	COG1216	Glycosyl transferase, family 2
EAH50_RS06010	COG0463	Glycosyl transferase, family 2
EAH50_RS06035	COG3039	Transposase
EAH50_RS06045	COG0582	viral genome integration into host DNA
EAH50_RS06055	COG1811	Na channel or pump
EAH50_RS06060	COG1982	Orn Lys Arg decarboxylase major
EAH50_RS06065	COG2211	Major facilitator Superfamily
EAH50_RS06080	COG1194	a g-specific adenine glycosylase
EAH50_RS06090	COG3171	Protein conserved in bacteria
EAH50_RS06100	COG0252	asparaginase activity
EAH50_RS06110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAH50_RS06115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EAH50_RS06125	COG0762	integral membrane protein
EAH50_RS06130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EAH50_RS06135	COG2805	Type II/IV secretion system protein
EAH50_RS06150	COG0189	ligase activity
EAH50_RS06155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAH50_RS06160	COG2356	endonuclease I
EAH50_RS06170	COG2814	Major facilitator Superfamily
EAH50_RS06195	COG1166	arginine decarboxylase activity
EAH50_RS06205	COG0501	Belongs to the peptidase M48B family
EAH50_RS06210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAH50_RS06215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS06220	COG2213	PTS system mannitol-specific
EAH50_RS06225	COG1063	alcohol dehydrogenase
EAH50_RS06230	COG1494	fructose-1,6-bisphosphatase
EAH50_RS06235	COG3722	fumarate hydratase activity
EAH50_RS06240	COG1072	(Pantothenic acid kinase))
EAH50_RS06255	COG0191	fructose-bisphosphate aldolase activity
EAH50_RS06260	COG0668	transmembrane transport
EAH50_RS06265	COG1279	arginine transmembrane transporter activity
EAH50_RS06270	COG2968	Membrane
EAH50_RS06275	COG0583	DNA-binding transcription factor activity
EAH50_RS06280	COG0427	acetyl-CoA hydrolase
EAH50_RS06285	COG1024	Enoyl-CoA hydratase
EAH50_RS06290	COG1703	isobutyryl-CoA mutase activity
EAH50_RS06295	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EAH50_RS06295	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EAH50_RS06315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAH50_RS06325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAH50_RS06345	COG0006	proline dipeptidase activity
EAH50_RS06350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAH50_RS06355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAH50_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS06385	COG2723	6-phospho-beta-galactosidase activity
EAH50_RS06395	COG1272	protein, Hemolysin III
EAH50_RS06405	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAH50_RS06415	COG0716	FMN binding
EAH50_RS06420	COG4974	Belongs to the 'phage' integrase family
EAH50_RS06425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAH50_RS06430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAH50_RS06440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EAH50_RS06460	COG2233	PERMEase
EAH50_RS06465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS06465	COG0493	'glutamate synthase
EAH50_RS06470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS06475	COG2252	PERMEase
EAH50_RS06480	COG0402	S-adenosylhomocysteine deaminase activity
EAH50_RS06485	COG2233	PERMEase
EAH50_RS06490	COG2080	2 iron, 2 sulfur cluster binding
EAH50_RS06490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAH50_RS06495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EAH50_RS06500	COG0402	S-adenosylhomocysteine deaminase activity
EAH50_RS06505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS06505	COG0493	'glutamate synthase
EAH50_RS06510	COG2068	MobA-Related Protein
EAH50_RS06515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAH50_RS06520	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EAH50_RS06520	COG3608	succinylglutamate desuccinylase aspartoacylase
EAH50_RS06525	COG0549	Belongs to the carbamate kinase family
EAH50_RS06535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAH50_RS06540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAH50_RS06545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAH50_RS06550	COG3829	transcription factor binding
EAH50_RS06555	COG2080	2 iron, 2 sulfur cluster binding
EAH50_RS06560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EAH50_RS06565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAH50_RS06570	COG4942	peptidase
EAH50_RS06590	COG2771	luxR family
EAH50_RS06595	COG3710	Transcriptional regulator
EAH50_RS06605	COG3039	Transposase
EAH50_RS06610	COG0814	amino acid
EAH50_RS06615	COG0183	Belongs to the thiolase family
EAH50_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS06630	COG2814	Major facilitator Superfamily
EAH50_RS06635	COG1794	racemase activity, acting on amino acids and derivatives
EAH50_RS06640	COG0583	DNA-binding transcription factor activity
EAH50_RS06650	COG1609	Transcriptional regulator
EAH50_RS06665	COG0667	Aldo Keto reductase
EAH50_RS06675	COG0861	Integral membrane protein TerC family
EAH50_RS06695	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
EAH50_RS06715	COG2165	general secretion pathway protein
EAH50_RS06720	COG4795	General secretion pathway protein
EAH50_RS06730	COG4967	type IV pilus modification protein PilV
EAH50_RS06735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EAH50_RS06745	COG1074	ATP-dependent DNA helicase activity
EAH50_RS06750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAH50_RS06755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAH50_RS06755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EAH50_RS06760	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAH50_RS06780	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EAH50_RS06785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAH50_RS06790	COG2166	iron-sulfur cluster assembly
EAH50_RS06795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAH50_RS06805	COG0583	DNA-binding transcription factor activity
EAH50_RS06810	COG2363	Small membrane protein
EAH50_RS06820	COG1349	DNA-binding transcription factor activity
EAH50_RS06830	COG1070	Carbohydrate kinase
EAH50_RS06840	COG0738	Major facilitator superfamily
EAH50_RS06845	COG0235	Class ii aldolase
EAH50_RS06850	COG1454	alcohol dehydrogenase
EAH50_RS06860	COG1760	l-serine dehydratase
EAH50_RS06865	COG0814	amino acid
EAH50_RS06870	COG1611	Belongs to the LOG family
EAH50_RS06885	COG3098	single-species biofilm formation
EAH50_RS06890	COG0564	pseudouridine synthase activity
EAH50_RS06895	COG0716	FMN binding
EAH50_RS06900	COG2271	Major facilitator Superfamily
EAH50_RS06905	COG4948	Mandelate Racemase Muconate Lactonizing
EAH50_RS06910	COG4948	Mandelate Racemase Muconate Lactonizing
EAH50_RS06915	COG2205	protein histidine kinase activity
EAH50_RS06915	COG3437	response regulator, receiver
EAH50_RS06915	COG3850	Histidine kinase
EAH50_RS06915	COG4999	Histidine kinase
EAH50_RS06920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAH50_RS06925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAH50_RS06930	COG2336	PFAM SpoVT AbrB
EAH50_RS06935	COG2337	Toxic component of a toxin-antitoxin (TA) module
EAH50_RS06940	COG3956	TIGRFAM MazG family protein
EAH50_RS06955	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EAH50_RS06965	COG0602	queuosine metabolic process
EAH50_RS06975	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAH50_RS06980	COG0644	oxidoreductase
EAH50_RS06985	COG0720	synthase
EAH50_RS06995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAH50_RS07015	COG3385	transposase activity
EAH50_RS07040	COG1857	crispr-associated protein
EAH50_RS07055	COG1518	maintenance of DNA repeat elements
EAH50_RS07060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAH50_RS07065	COG2234	aminopeptidase activity
EAH50_RS07120	COG1388	LysM domain
EAH50_RS07120	COG4942	peptidase
EAH50_RS07125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAH50_RS07130	COG2610	gluconate transmembrane transporter activity
EAH50_RS07135	COG3622	Belongs to the hyi family
EAH50_RS07140	COG0235	Class ii aldolase
EAH50_RS07145	COG3395	kinase activity
EAH50_RS07150	COG2084	Dehydrogenase
EAH50_RS07155	COG1349	DNA-binding transcription factor activity
EAH50_RS07160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAH50_RS07180	COG3604	Transcriptional regulator
EAH50_RS07185	COG0309	Hydrogenase expression formation protein (HypE)
EAH50_RS07190	COG0409	Hydrogenase expression formation protein
EAH50_RS07195	COG0298	carbon dioxide binding
EAH50_RS07200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EAH50_RS07205	COG0375	protein maturation
EAH50_RS07215	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS07220	COG0651	ATP synthesis coupled electron transport
EAH50_RS07225	COG0650	Formate hydrogenlyase subunit 4
EAH50_RS07230	COG3261	NADH dehydrogenase
EAH50_RS07230	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EAH50_RS07235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAH50_RS07240	COG3260	NADH ubiquinone oxidoreductase 20
EAH50_RS07250	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EAH50_RS07255	COG2723	6-phospho-beta-galactosidase activity
EAH50_RS07260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS07260	COG1263	PTS System
EAH50_RS07265	COG1609	Transcriptional regulator
EAH50_RS07270	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS07275	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EAH50_RS07295	COG0517	IMP dehydrogenase activity
EAH50_RS07295	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAH50_RS07300	COG1349	DNA-binding transcription factor activity
EAH50_RS07305	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS07310	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS07320	COG3732	PTS system glucitol sorbitol-specific
EAH50_RS07325	COG3730	PTS system glucitol sorbitol-specific
EAH50_RS07330	COG2951	lytic endotransglycosylase activity
EAH50_RS07335	COG1546	Belongs to the CinA family
EAH50_RS07355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EAH50_RS07385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAH50_RS07390	COG1238	metal cluster binding
EAH50_RS07405	COG2814	Major facilitator Superfamily
EAH50_RS07410	COG1566	PFAM secretion protein HlyD family protein
EAH50_RS07415	COG1846	Transcriptional regulator
EAH50_RS07425	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EAH50_RS07430	COG2814	Major facilitator Superfamily
EAH50_RS07440	COG2113	Glycine betaine
EAH50_RS07445	COG4176	ABC-type proline glycine betaine transport system permease component
EAH50_RS07450	COG4175	Glycine betaine
EAH50_RS07460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAH50_RS07465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAH50_RS07475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAH50_RS07480	COG4575	ribosome binding
EAH50_RS07495	COG2916	Histone family protein nucleoid-structuring protein H-NS
EAH50_RS07500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAH50_RS07505	COG0640	Transcriptional regulator
EAH50_RS07510	COG0401	homolog of Blt101
EAH50_RS07515	COG1652	LysM domain
EAH50_RS07520	COG1802	Transcriptional regulator
EAH50_RS07525	COG1113	amino acid transport
EAH50_RS07530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAH50_RS07535	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS07540	COG0579	oxidoreductase
EAH50_RS07580	COG3468	outer membrane autotransporter barrel domain protein
EAH50_RS07595	COG2867	negative regulation of translational initiation
EAH50_RS07605	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAH50_RS07610	COG0497	DNA recombination
EAH50_RS07630	COG4536	flavin adenine dinucleotide binding
EAH50_RS07635	COG4137	Cytochrome C assembly protein
EAH50_RS07640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAH50_RS07665	COG2885	chlorophyll binding
EAH50_RS07670	COG2199	diguanylate cyclase activity
EAH50_RS07685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAH50_RS07690	COG1605	Chorismate mutase
EAH50_RS07690	COG0287	Prephenate dehydrogenase
EAH50_RS07695	COG1605	Chorismate mutase
EAH50_RS07695	COG0077	Prephenate dehydratase
EAH50_RS07705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAH50_RS07710	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAH50_RS07715	COG0564	pseudouridine synthase activity
EAH50_RS07720	COG1496	oxidoreductase activity
EAH50_RS07725	COG0542	response to heat
EAH50_RS07750	COG0477	Major facilitator Superfamily
EAH50_RS07755	COG5544	Lipoprotein
EAH50_RS07760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAH50_RS07765	COG0045	succinate-CoA ligase (ADP-forming) activity
EAH50_RS07765	COG1042	CoA-binding domain protein
EAH50_RS07765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAH50_RS07770	COG3148	PFAM DTW domain containing protein
EAH50_RS07775	COG3118	belongs to the thioredoxin family
EAH50_RS07780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAH50_RS07800	COG0583	DNA-binding transcription factor activity
EAH50_RS07805	COG0513	Belongs to the DEAD box helicase family
EAH50_RS07815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAH50_RS07825	COG1595	DNA-templated transcription, initiation
EAH50_RS07830	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EAH50_RS07835	COG3026	antisigma factor binding
EAH50_RS07840	COG3086	response to oxidative stress
EAH50_RS07850	COG0681	Belongs to the peptidase S26 family
EAH50_RS07870	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAH50_RS07885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS07890	COG1737	Transcriptional regulator
EAH50_RS07895	COG0560	Phosphoserine phosphatase
EAH50_RS07910	COG0047	phosphoribosylformylglycinamidine synthase activity
EAH50_RS07910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAH50_RS07915	COG2205	protein histidine kinase activity
EAH50_RS07920	COG3170	Tfp pilus assembly protein FimV
EAH50_RS07925	COG2204	response regulator
EAH50_RS07930	COG0347	Belongs to the P(II) protein family
EAH50_RS07935	COG1017	nitric oxide dioxygenase activity
EAH50_RS07935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAH50_RS07945	COG1940	carbohydrate kinase activity
EAH50_RS07950	COG0457	Tetratricopeptide repeat
EAH50_RS07970	COG1129	ABC transporter
EAH50_RS07975	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS07980	COG1063	alcohol dehydrogenase
EAH50_RS07985	COG2017	converts alpha-aldose to the beta-anomer
EAH50_RS07990	COG2259	Doxx family
EAH50_RS08015	COG4638	Rieske (2fe-2S)
EAH50_RS08020	COG0583	DNA-binding transcription factor activity
EAH50_RS08025	COG2814	Major facilitator Superfamily
EAH50_RS08030	COG3711	transcriptional antiterminator
EAH50_RS08035	COG1073	alpha beta
EAH50_RS08040	COG0483	inositol monophosphate 1-phosphatase activity
EAH50_RS08060	COG0822	iron-sulfur transferase activity
EAH50_RS08080	COG0633	Ferredoxin
EAH50_RS08085	COG2975	iron-sulfur cluster assembly
EAH50_RS08100	COG2897	thiosulfate sulfurtransferase activity
EAH50_RS08105	COG2373	Large extracellular alpha-helical protein
EAH50_RS08110	COG4953	penicillin-binding protein 1C
EAH50_RS08140	COG2976	Protein conserved in bacteria
EAH50_RS08155	COG1645	bacterial-type flagellum-dependent swarming motility
EAH50_RS08165	COG0516	GMP reductase activity
EAH50_RS08165	COG0517	IMP dehydrogenase activity
EAH50_RS08185	COG2200	EAL domain
EAH50_RS08190	COG0248	Ppx GppA phosphatase
EAH50_RS08195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EAH50_RS08200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAH50_RS08215	COG2233	PERMEase
EAH50_RS08225	COG1393	Belongs to the ArsC family
EAH50_RS08230	COG4783	chaperone-mediated protein folding
EAH50_RS08235	COG0628	permease
EAH50_RS08240	COG2116	formate transmembrane transporter activity
EAH50_RS08245	COG3604	Transcriptional regulator
EAH50_RS08255	COG3260	NADH ubiquinone oxidoreductase 20
EAH50_RS08260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAH50_RS08265	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EAH50_RS08265	COG3261	NADH dehydrogenase
EAH50_RS08270	COG0651	ATP synthesis coupled electron transport
EAH50_RS08275	COG4237	Hydrogenase 4 membrane
EAH50_RS08280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAH50_RS08285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAH50_RS08295	COG0651	ATP synthesis coupled electron transport
EAH50_RS08300	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS08305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAH50_RS08310	COG2716	regulation of RNA biosynthetic process
EAH50_RS08320	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EAH50_RS08330	COG2321	neutral zinc metallopeptidase
EAH50_RS08340	COG0400	carboxylic ester hydrolase activity
EAH50_RS08355	COG1393	Belongs to the ArsC family
EAH50_RS08365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAH50_RS08370	COG3850	Histidine kinase
EAH50_RS08375	COG0493	'glutamate synthase
EAH50_RS08375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS08385	COG5342	invasion associated locus B
EAH50_RS08390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAH50_RS08395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAH50_RS08400	COG0281	malic enzyme
EAH50_RS08400	COG0280	phosphate acetyltransferase
EAH50_RS08405	COG4810	utilization protein
EAH50_RS08410	COG4917	ethanolamine utilization protein
EAH50_RS08415	COG4766	ethanolamine catabolic process
EAH50_RS08420	COG4812	Cobalamin adenosyltransferase
EAH50_RS08425	COG0280	phosphate acetyltransferase
EAH50_RS08430	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EAH50_RS08435	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EAH50_RS08440	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS08445	COG4820	ethanolamine utilization protein (EutJ)
EAH50_RS08450	COG1454	alcohol dehydrogenase
EAH50_RS08455	COG3192	ethanolamine utilization protein
EAH50_RS08460	COG4819	ethanolamine utilization protein
EAH50_RS08465	COG4303	Ethanolamine ammonia lyase large subunit
EAH50_RS08475	COG4816	utilization protein
EAH50_RS08480	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EAH50_RS08485	COG2207	Transcriptional regulator
EAH50_RS08495	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAH50_RS08515	COG2837	iron assimilation
EAH50_RS08520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAH50_RS08525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS08525	COG1263	PTS System
EAH50_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS08545	COG4150	thiosulfate binding
EAH50_RS08550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EAH50_RS08555	COG4208	sulfate ABC transporter
EAH50_RS08560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAH50_RS08565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EAH50_RS08580	COG2190	(PTS) system
EAH50_RS08585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAH50_RS08590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS08595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EAH50_RS08615	COG3530	Putative quorum-sensing-regulated virulence factor
EAH50_RS08620	COG0385	Bile acid
EAH50_RS08635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EAH50_RS08650	COG0583	DNA-binding transcription factor activity
EAH50_RS08685	COG3415	Transposase
EAH50_RS08690	COG3415	Transposase
EAH50_RS08705	COG2200	EAL domain
EAH50_RS08705	COG2199	diguanylate cyclase activity
EAH50_RS08710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAH50_RS08735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS08740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS08745	COG0006	proline dipeptidase activity
EAH50_RS08750	COG1363	Peptidase, m42
EAH50_RS08755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS08755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS08755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAH50_RS08760	COG2207	Transcriptional regulator
EAH50_RS08765	COG3279	Response regulator of the LytR AlgR family
EAH50_RS08770	COG3275	phosphorelay sensor kinase activity
EAH50_RS08775	COG0436	Aminotransferase
EAH50_RS08785	COG1560	Kdo2-lipid A biosynthetic process
EAH50_RS08810	COG0028	Belongs to the TPP enzyme family
EAH50_RS08835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAH50_RS08840	COG0784	Response regulator, receiver
EAH50_RS08840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS08840	COG2198	Histidine kinase
EAH50_RS08840	COG2205	protein histidine kinase activity
EAH50_RS08845	COG2197	response regulator
EAH50_RS08850	COG1566	PFAM secretion protein HlyD family protein
EAH50_RS08855	COG0477	Major facilitator Superfamily
EAH50_RS08865	COG2610	gluconate transmembrane transporter activity
EAH50_RS08870	COG0583	DNA-binding transcription factor activity
EAH50_RS08910	COG3723	Recombinational DNA repair protein, rece pathway
EAH50_RS08970	COG0305	Participates in initiation and elongation during chromosome replication
EAH50_RS09050	COG3646	Phage regulatory protein
EAH50_RS09065	COG1802	Transcriptional regulator
EAH50_RS09065	COG4626	Terminase
EAH50_RS09075	COG4695	Portal protein
EAH50_RS09165	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAH50_RS09195	COG0582	viral genome integration into host DNA
EAH50_RS09205	COG2116	formate transmembrane transporter activity
EAH50_RS09210	COG2853	Lipoprotein
EAH50_RS09220	COG2067	long-chain fatty acid transport protein
EAH50_RS09225	COG3691	Protein conserved in bacteria
EAH50_RS09240	COG2062	phosphohistidine phosphatase, SixA
EAH50_RS09245	COG3539	Fimbrial protein
EAH50_RS09255	COG3121	Chaperone
EAH50_RS09260	COG3539	Fimbrial protein
EAH50_RS09265	COG3539	Fimbrial protein
EAH50_RS09270	COG3539	Fimbrial protein
EAH50_RS09285	COG2890	protein-(glutamine-N5) methyltransferase activity
EAH50_RS09300	COG0730	response to heat
EAH50_RS09305	COG3101	peptidyl-lysine hydroxylation
EAH50_RS09320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAH50_RS09325	COG2814	Major facilitator Superfamily
EAH50_RS09340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAH50_RS09350	COG0586	Pfam SNARE associated Golgi protein
EAH50_RS09360	COG0285	dihydrofolate synthase activity
EAH50_RS09365	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EAH50_RS09370	COG1286	toxin biosynthetic process
EAH50_RS09375	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EAH50_RS09380	COG0163	prenyltransferase activity
EAH50_RS09385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS09390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS09395	COG4215	(ABC) transporter
EAH50_RS09400	COG4160	amino acid transport
EAH50_RS09405	COG4598	ABC transporter
EAH50_RS09410	COG5464	transposase or invertase
EAH50_RS09415	COG1090	epimerase
EAH50_RS09420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAH50_RS09425	COG0625	glutathione transferase activity
EAH50_RS09430	COG0625	glutathione transferase activity
EAH50_RS09435	COG0622	Phosphoesterase
EAH50_RS09440	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EAH50_RS09445	COG1288	antiporter activity
EAH50_RS09450	COG0280	phosphate acetyltransferase
EAH50_RS09450	COG0857	belongs to the CobB CobQ family
EAH50_RS09455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAH50_RS09470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAH50_RS09475	COG0471	metal ion transport
EAH50_RS09475	COG0490	domain, Protein
EAH50_RS09485	COG0436	Aminotransferase
EAH50_RS09490	COG0583	DNA-binding transcription factor activity
EAH50_RS09510	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EAH50_RS09515	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EAH50_RS09520	COG1034	ATP synthesis coupled electron transport
EAH50_RS09535	COG0839	Belongs to the complex I subunit 6 family
EAH50_RS09545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAH50_RS09550	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAH50_RS09570	COG5160	protein modification by small protein removal
EAH50_RS09580	COG2153	protein acetylation
EAH50_RS09585	COG4575	ribosome binding
EAH50_RS09590	COG1169	isochorismate synthase
EAH50_RS09605	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EAH50_RS09615	COG0318	PFAM AMP-dependent synthetase and ligase
EAH50_RS09680	COG1414	Transcriptional regulator
EAH50_RS09690	COG2271	Major facilitator Superfamily
EAH50_RS09705	COG5464	transposase or invertase
EAH50_RS09710	COG0247	lactate metabolic process
EAH50_RS09720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAH50_RS09725	COG2271	Major facilitator Superfamily
EAH50_RS09730	COG0584	glycerophosphoryl diester phosphodiesterase
EAH50_RS09740	COG3642	lipopolysaccharide core region biosynthetic process
EAH50_RS09745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAH50_RS09750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAH50_RS09755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAH50_RS09760	COG3468	outer membrane autotransporter barrel domain protein
EAH50_RS09770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAH50_RS09775	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
EAH50_RS09780	COG3234	Protein of unknown function (DUF1175)
EAH50_RS09785	COG2373	Large extracellular alpha-helical protein
EAH50_RS09790	COG5445	Predicted secreted protein (DUF2300)
EAH50_RS09795	COG4676	Protein conserved in bacteria
EAH50_RS09800	COG0183	Belongs to the thiolase family
EAH50_RS09805	COG2031	fatty acid transporter
EAH50_RS09810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAH50_RS09815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EAH50_RS09820	COG2204	response regulator
EAH50_RS09825	COG3852	Histidine kinase
EAH50_RS09830	COG0784	Response regulator, receiver
EAH50_RS09830	COG2205	protein histidine kinase activity
EAH50_RS09835	COG2197	response regulator
EAH50_RS09840	COG2198	Histidine kinase
EAH50_RS09840	COG0642	Histidine kinase
EAH50_RS09845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAH50_RS09850	COG1477	protein flavinylation
EAH50_RS09855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAH50_RS09855	COG2169	Transcriptional regulator
EAH50_RS09860	COG3145	DNA-N1-methyladenine dioxygenase activity
EAH50_RS09865	COG4615	Cyclic peptide transporter
EAH50_RS09880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS09880	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAH50_RS09885	COG3062	negative regulation of establishment of protein localization
EAH50_RS09895	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS09900	COG0348	domain, Protein
EAH50_RS09905	COG3043	anaerobic respiration
EAH50_RS09910	COG3005	denitrification pathway
EAH50_RS09915	COG4133	protoheme IX ABC transporter activity
EAH50_RS09920	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAH50_RS09925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAH50_RS09930	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAH50_RS09940	COG1138	Cytochrome C-type biogenesis protein
EAH50_RS09945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EAH50_RS09950	COG4235	cytochrome complex assembly
EAH50_RS09950	COG3088	subunit of a heme lyase
EAH50_RS09955	COG2197	response regulator
EAH50_RS09960	COG3468	outer membrane autotransporter barrel domain protein
EAH50_RS09970	COG3083	sulfuric ester hydrolase activity
EAH50_RS09990	COG1061	Type III restriction enzyme res subunit
EAH50_RS09995	COG1187	pseudouridine synthase activity
EAH50_RS10000	COG2814	Major facilitator Superfamily
EAH50_RS10010	COG4172	Belongs to the ABC transporter superfamily
EAH50_RS10015	COG4239	(ABC) transporter, permease
EAH50_RS10020	COG4174	ABC transporter (Permease)
EAH50_RS10025	COG4166	transmembrane transport
EAH50_RS10030	COG2200	EAL domain
EAH50_RS10035	COG0791	NLP P60 protein
EAH50_RS10045	COG2826	transposase and inactivated derivatives, IS30 family
EAH50_RS10055	COG0523	cobalamin synthesis protein
EAH50_RS10060	COG0246	Mannitol dehydrogenase
EAH50_RS10075	COG2814	Major facilitator Superfamily
EAH50_RS10080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS10080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS10085	COG1105	Belongs to the carbohydrate kinase PfkB family
EAH50_RS10090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS10090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS10090	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EAH50_RS10095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS10100	COG2313	pseudouridylate synthase activity
EAH50_RS10105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAH50_RS10120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAH50_RS10125	COG1522	sequence-specific DNA binding
EAH50_RS10125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS10135	COG2855	membrane
EAH50_RS10140	COG0583	DNA-binding transcription factor activity
EAH50_RS10145	COG0833	amino acid
EAH50_RS10150	COG4771	TonB-dependent receptor
EAH50_RS10165	COG2311	Membrane
EAH50_RS10170	COG1609	Transcriptional regulator
EAH50_RS10175	COG1879	ABC-type sugar transport system periplasmic component
EAH50_RS10180	COG1129	ABC transporter
EAH50_RS10185	COG4211	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS10190	COG0167	dihydroorotate dehydrogenase activity
EAH50_RS10190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EAH50_RS10195	COG0493	'glutamate synthase
EAH50_RS10205	COG2949	membrane
EAH50_RS10215	COG1346	cytolysis
EAH50_RS10225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAH50_RS10240	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS10245	COG0586	Pfam SNARE associated Golgi protein
EAH50_RS10255	COG1686	Belongs to the peptidase S11 family
EAH50_RS10260	COG0277	FAD linked oxidase domain protein
EAH50_RS10265	COG1472	Belongs to the glycosyl hydrolase 3 family
EAH50_RS10270	COG1732	Glycine betaine
EAH50_RS10275	COG1174	glycine betaine transport
EAH50_RS10280	COG1125	glycine betaine transport
EAH50_RS10285	COG1174	glycine betaine transport
EAH50_RS10295	COG0789	Transcriptional regulator
EAH50_RS10300	COG3275	phosphorelay sensor kinase activity
EAH50_RS10305	COG3279	Response regulator of the LytR AlgR family
EAH50_RS10310	COG4807	Protein conserved in bacteria
EAH50_RS10315	COG4808	Protein conserved in bacteria
EAH50_RS10320	COG4715	Zinc finger, swim domain protein
EAH50_RS10325	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EAH50_RS10330	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EAH50_RS10335	COG0714	Associated with various cellular activities
EAH50_RS10345	COG3831	ATPase activity
EAH50_RS10360	COG0489	protein tyrosine kinase activity
EAH50_RS10370	COG3539	Fimbrial protein
EAH50_RS10375	COG3121	Chaperone
EAH50_RS10380	COG3188	usher protein
EAH50_RS10385	COG3539	Fimbrial protein
EAH50_RS10390	COG5455	response to cobalt ion
EAH50_RS10410	COG0351	phosphomethylpyrimidine kinase
EAH50_RS10415	COG3757	hydrolase, family 25
EAH50_RS10420	COG2188	Transcriptional regulator
EAH50_RS10425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS10430	COG1397	ADP-ribosylglycohydrolase
EAH50_RS10435	COG2211	Major facilitator Superfamily
EAH50_RS10440	COG1830	Aldolase
EAH50_RS10460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS10465	COG3414	Phosphotransferase system galactitol-specific IIB component
EAH50_RS10485	COG1063	alcohol dehydrogenase
EAH50_RS10510	COG0826	peptidase U32
EAH50_RS10520	COG0745	RESPONSE REGULATOR receiver
EAH50_RS10525	COG2205	protein histidine kinase activity
EAH50_RS10560	COG4245	von Willebrand factor, type A
EAH50_RS10565	COG0631	protein serine/threonine phosphatase activity
EAH50_RS10570	COG3779	Protein conserved in bacteria
EAH50_RS10575	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EAH50_RS10580	COG0443	Heat shock 70 kDa protein
EAH50_RS10585	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EAH50_RS10590	COG5002	protein histidine kinase activity
EAH50_RS10590	COG5001	Diguanylate cyclase
EAH50_RS10590	COG3447	MASE1 domain protein
EAH50_RS10595	COG0572	uridine kinase
EAH50_RS10605	COG2982	Protein involved in outer membrane biogenesis
EAH50_RS10610	COG1253	flavin adenine dinucleotide binding
EAH50_RS10615	COG1596	polysaccharide export
EAH50_RS10620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAH50_RS10625	COG3206	protein involved in exopolysaccharide biosynthesis
EAH50_RS10625	COG0489	protein tyrosine kinase activity
EAH50_RS10630	COG0463	Glycosyl transferase, family 2
EAH50_RS10635	COG1045	serine acetyltransferase
EAH50_RS10650	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EAH50_RS10660	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EAH50_RS10685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EAH50_RS10690	COG0131	Imidazoleglycerol-phosphate dehydratase
EAH50_RS10690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAH50_RS10700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EAH50_RS10715	COG2161	toxin-antitoxin pair type II binding
EAH50_RS10720	COG4115	mRNA cleavage
EAH50_RS10725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAH50_RS10730	COG0583	DNA-binding transcription factor activity
EAH50_RS10740	COG0531	amino acid
EAH50_RS10745	COG2391	methyltransferase activity
EAH50_RS10750	COG0425	Belongs to the sulfur carrier protein TusA family
EAH50_RS10755	COG2925	Exonuclease
EAH50_RS10760	COG1686	Belongs to the peptidase S11 family
EAH50_RS10770	COG1289	transmembrane transporter activity
EAH50_RS10815	COG2003	Belongs to the UPF0758 family
EAH50_RS10855	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EAH50_RS10870	COG1376	ErfK ybiS ycfS ynhG family protein
EAH50_RS10880	COG0583	DNA-binding transcription factor activity
EAH50_RS10885	COG0583	DNA-binding transcription factor activity
EAH50_RS10895	COG0534	Mate efflux family protein
EAH50_RS10910	COG0217	transcriptional regulatory protein
EAH50_RS10915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAH50_RS10920	COG0477	Major facilitator Superfamily
EAH50_RS10935	COG4932	domain protein
EAH50_RS10935	COG1388	LysM domain
EAH50_RS10935	COG2373	Large extracellular alpha-helical protein
EAH50_RS10955	COG3038	cytochrome b561
EAH50_RS10960	COG3443	Belongs to the bacterial solute-binding protein 9 family
EAH50_RS10975	COG2351	hydroxyisourate hydrolase activity
EAH50_RS10995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAH50_RS11010	COG1418	mRNA catabolic process
EAH50_RS11015	COG0270	DNA (cytosine-5-)-methyltransferase activity
EAH50_RS11020	COG3727	T/G mismatch-specific endonuclease activity
EAH50_RS11025	COG0697	spore germination
EAH50_RS11030	COG2354	Protein conserved in bacteria
EAH50_RS11035	COG5475	Uncharacterized small protein (DUF2158)
EAH50_RS11045	COG3706	GGDEF domain
EAH50_RS11065	COG2197	response regulator
EAH50_RS11070	COG1684	flagellar biosynthetic protein fliR
EAH50_RS11075	COG1987	bacterial-type flagellum assembly
EAH50_RS11080	COG1338	Plays a role in the flagellum-specific transport system
EAH50_RS11085	COG3190	flagellar
EAH50_RS11090	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAH50_RS11095	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAH50_RS11100	COG1580	Controls the rotational direction of flagella during chemotaxis
EAH50_RS11105	COG3144	bacterial-type flagellum assembly
EAH50_RS11110	COG2882	bacterial-type flagellum organization
EAH50_RS11115	COG1157	protein secretion by the type III secretion system
EAH50_RS11120	COG1317	bacterial-type flagellum organization
EAH50_RS11125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAH50_RS11130	COG1766	The M ring may be actively involved in energy transduction
EAH50_RS11145	COG2135	peptidase activity
EAH50_RS11150	COG0425	Belongs to the sulfur carrier protein TusA family
EAH50_RS11155	COG2391	methyltransferase activity
EAH50_RS11165	COG0366	Alpha amylase catalytic
EAH50_RS11175	COG1516	flagellar protein fliS
EAH50_RS11180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EAH50_RS11185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAH50_RS11190	COG1191	sigma factor activity
EAH50_RS11200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS11210	COG0765	amino acid transport
EAH50_RS11215	COG1126	abc transporter atp-binding protein
EAH50_RS11220	COG2197	response regulator
EAH50_RS11235	COG2197	response regulator
EAH50_RS11375	COG3318	Belongs to the UPF0149 family
EAH50_RS11375	COG3012	SEC-C Motif Domain Protein
EAH50_RS11380	COG0814	amino acid
EAH50_RS11390	COG1528	Iron-storage protein
EAH50_RS11415	COG1528	Iron-storage protein
EAH50_RS11420	COG1879	ABC-type sugar transport system periplasmic component
EAH50_RS11425	COG1129	ABC transporter
EAH50_RS11430	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS11435	COG1877	trehalose-phosphatase activity
EAH50_RS11445	COG0589	response to stress
EAH50_RS11470	COG3102	Protein conserved in bacteria
EAH50_RS11485	COG3005	denitrification pathway
EAH50_RS11490	COG0243	molybdopterin cofactor binding
EAH50_RS11505	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EAH50_RS11510	COG1801	Protein of unknown function DUF72
EAH50_RS11515	COG1335	isochorismatase
EAH50_RS11525	COG0494	nUDIX hydrolase
EAH50_RS11530	COG0217	transcriptional regulatory protein
EAH50_RS11560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAH50_RS11570	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EAH50_RS11575	COG0739	heme binding
EAH50_RS11580	COG1560	Kdo2-lipid A biosynthetic process
EAH50_RS11595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAH50_RS11615	COG2182	Extracellular solute-binding protein
EAH50_RS11620	COG1175	transmembrane transport
EAH50_RS11625	COG3833	ABC-type maltose transport systems, permease component
EAH50_RS11650	COG0469	pyruvate kinase activity
EAH50_RS11655	COG1737	Transcriptional regulator
EAH50_RS11660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EAH50_RS11665	COG0129	dihydroxy-acid dehydratase activity
EAH50_RS11670	COG0800	Aldolase
EAH50_RS11680	COG3141	response to X-ray
EAH50_RS11690	COG2979	Protein of unknown function (DUF533)
EAH50_RS11695	COG1770	oligopeptidase
EAH50_RS11700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAH50_RS11705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAH50_RS11715	COG2372	response to copper ion
EAH50_RS11720	COG1276	copper resistance
EAH50_RS11730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAH50_RS11750	COG3008	intermembrane lipid transfer
EAH50_RS11755	COG2995	paraquat-inducible protein a
EAH50_RS11760	COG1956	GAF domain-containing protein
EAH50_RS11770	COG0793	Belongs to the peptidase S41A family
EAH50_RS11780	COG2814	Major facilitator Superfamily
EAH50_RS11785	COG1414	Transcriptional regulator
EAH50_RS11815	COG2226	methyltransferase
EAH50_RS11830	COG3716	PTS system mannose fructose sorbose family IID component
EAH50_RS11835	COG3715	PTS system
EAH50_RS11840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS11840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS11845	COG1253	flavin adenine dinucleotide binding
EAH50_RS11850	COG2200	EAL domain
EAH50_RS11855	COG1760	l-serine dehydratase
EAH50_RS11865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAH50_RS11880	COG0251	oxidation-reduction process
EAH50_RS11885	COG1199	ATP-dependent helicase activity
EAH50_RS11890	COG1214	PFAM Peptidase M22, glycoprotease
EAH50_RS11895	COG3065	identical protein binding
EAH50_RS11900	COG0318	PFAM AMP-dependent synthetase and ligase
EAH50_RS11905	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EAH50_RS11910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAH50_RS11915	COG4638	Rieske (2fe-2S)
EAH50_RS11920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAH50_RS11925	COG0473	3-isopropylmalate dehydrogenase activity
EAH50_RS11930	COG0583	DNA-binding transcription factor activity
EAH50_RS11940	COG3615	Tellurite resistance protein tehB
EAH50_RS11950	COG2261	transglycosylase associated protein
EAH50_RS11965	COG2203	Gaf domain
EAH50_RS11965	COG2199	diguanylate cyclase activity
EAH50_RS11970	COG3042	response to heat
EAH50_RS11975	COG3189	MarR family transcriptional regulator
EAH50_RS11980	COG2807	transmembrane transport
EAH50_RS11985	COG2207	Transcriptional regulator
EAH50_RS12000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAH50_RS12015	COG2199	diguanylate cyclase activity
EAH50_RS12020	COG2199	diguanylate cyclase activity
EAH50_RS12030	COG2766	serine protein kinase
EAH50_RS12035	COG3713	MltA-interacting MipA family protein
EAH50_RS12040	COG0656	L-ascorbic acid biosynthetic process
EAH50_RS12045	COG0676	glucose-6-phosphate 1-epimerase activity
EAH50_RS12050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAH50_RS12060	COG3139	Protein of unknown function (DUF1315)
EAH50_RS12065	COG1063	alcohol dehydrogenase
EAH50_RS12070	COG2271	Major facilitator Superfamily
EAH50_RS12075	COG1063	alcohol dehydrogenase
EAH50_RS12080	COG0191	fructose-bisphosphate aldolase activity
EAH50_RS12085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS12090	COG0667	Aldo Keto reductase
EAH50_RS12095	COG1349	DNA-binding transcription factor activity
EAH50_RS12100	COG2814	Major facilitator Superfamily
EAH50_RS12105	COG1335	isochorismatase
EAH50_RS12110	COG0252	asparaginase activity
EAH50_RS12115	COG0616	signal peptide processing
EAH50_RS12120	COG0778	Nitroreductase
EAH50_RS12130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAH50_RS12140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAH50_RS12150	COG0494	nUDIX hydrolase
EAH50_RS12155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EAH50_RS12160	COG2897	thiosulfate sulfurtransferase activity
EAH50_RS12165	COG4136	ATPase activity
EAH50_RS12170	COG4135	transport system, permease component
EAH50_RS12175	COG4134	Bacterial extracellular solute-binding protein
EAH50_RS12180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAH50_RS12185	COG0398	Pfam SNARE associated Golgi protein
EAH50_RS12195	COG0398	Pfam SNARE associated Golgi protein
EAH50_RS12200	COG0708	Exodeoxyribonuclease III
EAH50_RS12230	COG3678	ATP-independent chaperone mediated protein folding
EAH50_RS12240	COG0322	excinuclease ABC activity
EAH50_RS12250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAH50_RS12260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAH50_RS12265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAH50_RS12270	COG1447	Phosphotransferase system cellobiose-specific component IIA
EAH50_RS12275	COG1917	Cupin 2, conserved barrel domain protein
EAH50_RS12275	COG2169	Transcriptional regulator
EAH50_RS12280	COG1486	melibiose metabolic process
EAH50_RS12290	COG0753	catalase activity
EAH50_RS12305	COG1823	symporter activity
EAH50_RS12310	COG1988	membrane-bound metal-dependent
EAH50_RS12315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAH50_RS12325	COG3001	Fructosamine kinase
EAH50_RS12335	COG1105	Belongs to the carbohydrate kinase PfkB family
EAH50_RS12340	COG3137	Salt-induced outer membrane protein
EAH50_RS12400	COG0386	Belongs to the glutathione peroxidase family
EAH50_RS12410	COG0791	NLP P60 protein
EAH50_RS12415	COG2200	EAL domain
EAH50_RS12425	COG4256	Hemin uptake protein
EAH50_RS12430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAH50_RS12440	COG0574	Belongs to the PEP-utilizing enzyme family
EAH50_RS12440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAH50_RS12445	COG0318	PFAM AMP-dependent synthetase and ligase
EAH50_RS12450	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAH50_RS12455	COG0644	oxidoreductase
EAH50_RS12460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EAH50_RS12465	COG2086	electron transfer activity
EAH50_RS12470	COG1917	Cupin 2, conserved barrel domain protein
EAH50_RS12470	COG2207	Transcriptional regulator
EAH50_RS12475	COG1960	acyl-CoA dehydrogenase activity
EAH50_RS12480	COG4670	ketone body catabolic process
EAH50_RS12485	COG4670	ketone body catabolic process
EAH50_RS12505	COG2271	Major facilitator Superfamily
EAH50_RS12540	COG0628	permease
EAH50_RS12545	COG0277	FAD linked oxidase domain protein
EAH50_RS12545	COG0247	lactate metabolic process
EAH50_RS12550	COG2050	protein possibly involved in aromatic compounds catabolism
EAH50_RS12560	COG0316	Belongs to the HesB IscA family
EAH50_RS12565	COG0719	Fe-S assembly protein
EAH50_RS12570	COG0396	ATPase activity
EAH50_RS12575	COG0719	Fe-S assembly protein
EAH50_RS12590	COG1376	ErfK ybiS ycfS ynhG family protein
EAH50_RS12595	COG4238	major outer membrane lipoprotein
EAH50_RS12600	COG0469	pyruvate kinase activity
EAH50_RS12610	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS12615	COG2414	aldehyde ferredoxin oxidoreductase
EAH50_RS12625	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS12630	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EAH50_RS12640	COG4529	Protein conserved in bacteria
EAH50_RS12660	COG3468	outer membrane autotransporter barrel domain protein
EAH50_RS12670	COG0307	riboflavin synthase, alpha
EAH50_RS12675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EAH50_RS12680	COG2814	Major facilitator Superfamily
EAH50_RS12685	COG0583	DNA-binding transcription factor activity
EAH50_RS12700	COG2814	Major facilitator Superfamily
EAH50_RS12705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EAH50_RS12710	COG0791	NLP P60 protein
EAH50_RS12715	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAH50_RS12720	COG1201	RNA secondary structure unwinding
EAH50_RS12725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAH50_RS12730	COG0346	lactoylglutathione lyase activity
EAH50_RS12735	COG1902	pentaerythritol trinitrate reductase activity
EAH50_RS12740	COG1309	transcriptional regulator
EAH50_RS12745	COG3313	Fe-S protein
EAH50_RS12750	COG4989	oxidoreductase activity
EAH50_RS12755	COG2032	superoxide dismutase activity
EAH50_RS12760	COG1289	transmembrane transporter activity
EAH50_RS12780	COG3133	Outer membrane lipoprotein
EAH50_RS12790	COG3895	Periplasmic Protein
EAH50_RS12805	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EAH50_RS12810	COG0625	glutathione transferase activity
EAH50_RS12815	COG3104	oligopeptide transport
EAH50_RS12820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAH50_RS12830	COG4659	FMN binding
EAH50_RS12870	COG0673	inositol 2-dehydrogenase activity
EAH50_RS12880	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EAH50_RS12885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS12885	COG1263	PTS System
EAH50_RS12890	COG1609	Transcriptional regulator
EAH50_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS12900	COG1309	transcriptional regulator
EAH50_RS12905	COG3250	beta-galactosidase activity
EAH50_RS12920	COG5339	Protein conserved in bacteria
EAH50_RS12925	COG1482	cell wall glycoprotein biosynthetic process
EAH50_RS12930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAH50_RS12930	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAH50_RS12935	COG0114	fumarate hydratase activity
EAH50_RS12945	COG2205	protein histidine kinase activity
EAH50_RS12950	COG0745	RESPONSE REGULATOR receiver
EAH50_RS12955	COG3136	membrane protein required for alginate biosynthesis
EAH50_RS12965	COG0531	amino acid
EAH50_RS12975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EAH50_RS12980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EAH50_RS12985	COG0628	permease
EAH50_RS13010	COG3591	Belongs to the peptidase S1B family
EAH50_RS13025	COG2814	Major facilitator Superfamily
EAH50_RS13030	COG0583	DNA-binding transcription factor activity
EAH50_RS13035	COG1940	carbohydrate kinase activity
EAH50_RS13040	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EAH50_RS13050	COG3381	protein complex oligomerization
EAH50_RS13055	COG3302	dmso reductase anchor subunit
EAH50_RS13060	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS13065	COG0243	molybdopterin cofactor binding
EAH50_RS13070	COG0243	molybdopterin cofactor binding
EAH50_RS13115	COG0243	molybdopterin cofactor binding
EAH50_RS13130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAH50_RS13145	COG4948	Mandelate Racemase Muconate Lactonizing
EAH50_RS13150	COG1063	alcohol dehydrogenase
EAH50_RS13160	COG0582	viral genome integration into host DNA
EAH50_RS13170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAH50_RS13200	COG1396	sequence-specific DNA binding
EAH50_RS13250	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAH50_RS13255	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EAH50_RS13265	COG0477	Major facilitator Superfamily
EAH50_RS13270	COG0246	Mannitol dehydrogenase
EAH50_RS13280	COG1802	Transcriptional regulator
EAH50_RS13285	COG4221	oxidoreductase activity
EAH50_RS13290	COG0339	signal peptide processing
EAH50_RS13295	COG1546	Belongs to the CinA family
EAH50_RS13300	COG3111	PFAM Bacterial OB fold (BOF) protein
EAH50_RS13305	COG3706	GGDEF domain
EAH50_RS13315	COG2814	Major facilitator Superfamily
EAH50_RS13320	COG0697	spore germination
EAH50_RS13330	COG4977	sequence-specific DNA binding
EAH50_RS13335	COG1846	Transcriptional regulator
EAH50_RS13355	COG0583	DNA-binding transcription factor activity
EAH50_RS13360	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS13365	COG2066	Belongs to the glutaminase family
EAH50_RS13375	COG2199	diguanylate cyclase activity
EAH50_RS13385	COG3781	membrane
EAH50_RS13445	COG1396	sequence-specific DNA binding
EAH50_RS13450	COG3550	peptidyl-serine autophosphorylation
EAH50_RS13480	COG3539	Fimbrial protein
EAH50_RS13485	COG3539	Fimbrial protein
EAH50_RS13490	COG3539	Fimbrial protein
EAH50_RS13495	COG0243	molybdopterin cofactor binding
EAH50_RS13505	COG2207	Transcriptional regulator
EAH50_RS13510	COG3119	arylsulfatase activity
EAH50_RS13515	COG0641	radical SAM
EAH50_RS13530	COG4771	TonB-dependent receptor
EAH50_RS13535	COG0612	Peptidase, M16
EAH50_RS13540	COG0076	glutamate decarboxylase activity
EAH50_RS13545	COG0531	amino acid
EAH50_RS13550	COG1649	PFAM Uncharacterised BCR, COG1649
EAH50_RS13555	COG3706	GGDEF domain
EAH50_RS13560	COG2199	diguanylate cyclase activity
EAH50_RS13560	COG2202	Pas domain
EAH50_RS13560	COG2200	EAL domain
EAH50_RS13565	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EAH50_RS13570	COG0747	negative chemotaxis
EAH50_RS13575	COG0601	transmembrane transport
EAH50_RS13580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAH50_RS13585	COG0444	Belongs to the ABC transporter superfamily
EAH50_RS13590	COG4608	Belongs to the ABC transporter superfamily
EAH50_RS13595	COG1764	response to oxidative stress
EAH50_RS13615	COG1064	alcohol dehydrogenase
EAH50_RS13620	COG3093	addiction module antidote protein HigA
EAH50_RS13625	COG2864	formate dehydrogenase
EAH50_RS13630	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS13640	COG0697	spore germination
EAH50_RS13645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAH50_RS13650	COG4886	Leucine-rich repeat (LRR) protein
EAH50_RS13655	COG4886	Leucine-rich repeat (LRR) protein
EAH50_RS13660	COG2223	nitrite transmembrane transporter activity
EAH50_RS13665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EAH50_RS13670	COG1140	nitrate reductase beta subunit
EAH50_RS13675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAH50_RS13680	COG2181	nitrate reductase activity
EAH50_RS13685	COG0384	phenazine biosynthesis protein PhzF
EAH50_RS13690	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EAH50_RS13695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAH50_RS13705	COG5433	transposase activity
EAH50_RS13725	COG3209	COG3209 Rhs family protein
EAH50_RS13740	COG0625	glutathione transferase activity
EAH50_RS13745	COG1113	amino acid transport
EAH50_RS13750	COG3391	amine dehydrogenase activity
EAH50_RS13755	COG4772	TonB-dependent receptor
EAH50_RS13760	COG1802	Transcriptional regulator
EAH50_RS13765	COG2130	NADP-dependent
EAH50_RS13770	COG1247	-acetyltransferase
EAH50_RS13775	COG3238	Protein conserved in bacteria
EAH50_RS13805	COG1177	transmembrane transport
EAH50_RS13810	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAH50_RS13815	COG3842	ATPase activity
EAH50_RS13820	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAH50_RS13825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAH50_RS13830	COG1598	PFAM Uncharacterised protein family UPF0150
EAH50_RS13835	COG1724	mRNA binding
EAH50_RS13845	COG0826	peptidase U32
EAH50_RS13850	COG1396	sequence-specific DNA binding
EAH50_RS13855	COG3135	benzoate transporter
EAH50_RS13860	COG0675	Transposase, IS605 OrfB family
EAH50_RS13875	COG0500	methyltransferase
EAH50_RS13880	COG1275	C4-dicarboxylate transporter malic acid transport protein
EAH50_RS13885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAH50_RS13890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAH50_RS13895	COG2841	Protein conserved in bacteria
EAH50_RS13905	COG5383	Protein conserved in bacteria
EAH50_RS13910	COG0583	DNA-binding transcription factor activity
EAH50_RS13915	COG0840	transmembrane signaling receptor activity
EAH50_RS13935	COG3038	cytochrome b561
EAH50_RS13940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAH50_RS13945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAH50_RS13950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAH50_RS13955	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS13960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EAH50_RS13965	COG1643	Atp-dependent helicase
EAH50_RS13975	COG0671	phosphoesterase, PA-phosphatase related
EAH50_RS13975	COG2453	phosphatase
EAH50_RS13980	COG2267	carboxylic ester hydrolase activity
EAH50_RS13990	COG0667	Aldo Keto reductase
EAH50_RS13995	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAH50_RS14000	COG3327	negative regulation of DNA-templated transcription, initiation
EAH50_RS14005	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EAH50_RS14010	COG0183	Belongs to the thiolase family
EAH50_RS14015	COG2050	protein possibly involved in aromatic compounds catabolism
EAH50_RS14020	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAH50_RS14025	COG1024	Enoyl-CoA hydratase
EAH50_RS14030	COG1024	Enoyl-CoA hydratase
EAH50_RS14035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAH50_RS14040	COG2151	metal-sulfur cluster biosynthetic enzyme
EAH50_RS14045	COG3396	Phenylacetate-CoA oxygenase
EAH50_RS14050	COG3460	Phenylacetate-CoA oxygenase
EAH50_RS14055	COG3396	Phenylacetate-CoA oxygenase
EAH50_RS14060	COG2030	dehydratase
EAH50_RS14060	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS14065	COG3733	amine oxidase
EAH50_RS14070	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS14075	COG2207	Transcriptional regulator
EAH50_RS14080	COG3784	Protein of unknown function (DUF1318)
EAH50_RS14090	COG2911	Protein conserved in bacteria
EAH50_RS14095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAH50_RS14100	COG3187	Heat shock protein
EAH50_RS14105	COG3042	response to heat
EAH50_RS14110	COG0674	pyruvate-flavodoxin oxidoreductase activity
EAH50_RS14110	COG1013	pyruvate-flavodoxin oxidoreductase activity
EAH50_RS14110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EAH50_RS14110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAH50_RS14115	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAH50_RS14120	COG0589	response to stress
EAH50_RS14135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EAH50_RS14195	COG1475	DNA binding
EAH50_RS14200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAH50_RS14210	COG3772	lysozyme
EAH50_RS14235	COG3064	Membrane
EAH50_RS14265	COG2814	Major facilitator Superfamily
EAH50_RS14270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EAH50_RS14290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAH50_RS14350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAH50_RS14355	COG3723	Recombinational DNA repair protein, rece pathway
EAH50_RS14375	COG0582	viral genome integration into host DNA
EAH50_RS14385	COG0513	Belongs to the DEAD box helicase family
EAH50_RS14395	COG3706	GGDEF domain
EAH50_RS14400	COG2840	Smr protein MutS2
EAH50_RS14405	COG0583	DNA-binding transcription factor activity
EAH50_RS14410	COG1473	amidohydrolase
EAH50_RS14415	COG1473	amidohydrolase
EAH50_RS14420	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EAH50_RS14425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAH50_RS14430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAH50_RS14435	COG0589	response to stress
EAH50_RS14440	COG3182	Iron-regulated membrane protein
EAH50_RS14445	COG0668	transmembrane transport
EAH50_RS14450	COG4166	transmembrane transport
EAH50_RS14455	COG0583	DNA-binding transcription factor activity
EAH50_RS14460	COG1073	alpha beta
EAH50_RS14475	COG2866	Carboxypeptidase
EAH50_RS14480	COG4948	Mandelate Racemase Muconate Lactonizing
EAH50_RS14485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EAH50_RS14490	COG3283	Transcriptional regulator of aromatic amino acids metabolism
EAH50_RS14500	COG3106	COG3106 Predicted ATPase
EAH50_RS14505	COG1609	Transcriptional regulator
EAH50_RS14515	COG3842	ATPase activity
EAH50_RS14520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAH50_RS14525	COG1554	hydrolase, family 65, central catalytic
EAH50_RS14530	COG0673	inositol 2-dehydrogenase activity
EAH50_RS14535	COG1082	Xylose isomerase domain protein TIM barrel
EAH50_RS14540	COG1063	alcohol dehydrogenase
EAH50_RS14545	COG0395	ABC-type sugar transport system, permease component
EAH50_RS14550	COG1175	transmembrane transport
EAH50_RS14555	COG1653	transport
EAH50_RS14560	COG0366	Alpha amylase catalytic
EAH50_RS14565	COG0366	Alpha amylase catalytic
EAH50_RS14570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAH50_RS14580	COG1983	PspC domain protein
EAH50_RS14590	COG1842	Phage shock protein A
EAH50_RS14595	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EAH50_RS14600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAH50_RS14605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAH50_RS14610	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS14615	COG1396	sequence-specific DNA binding
EAH50_RS14615	COG1917	Cupin 2, conserved barrel domain protein
EAH50_RS14620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EAH50_RS14625	COG0174	glutamine synthetase
EAH50_RS14635	COG0531	amino acid
EAH50_RS14645	COG4166	transmembrane transport
EAH50_RS14650	COG4168	peptide transport system, permease
EAH50_RS14655	COG4171	peptide transport system, permease
EAH50_RS14660	COG4172	Belongs to the ABC transporter superfamily
EAH50_RS14665	COG4172	Belongs to the ABC transporter superfamily
EAH50_RS14670	COG2852	Protein conserved in bacteria
EAH50_RS14675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EAH50_RS14680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAH50_RS14680	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAH50_RS14695	COG5001	Diguanylate cyclase
EAH50_RS14705	COG1349	DNA-binding transcription factor activity
EAH50_RS14715	COG0023	Translation Initiation Factor
EAH50_RS14725	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EAH50_RS14730	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EAH50_RS14735	COG0671	phosphoesterase, PA-phosphatase related
EAH50_RS14745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAH50_RS14765	COG0583	DNA-binding transcription factor activity
EAH50_RS14770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAH50_RS14780	COG0616	signal peptide processing
EAH50_RS14785	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS14790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EAH50_RS14795	COG1187	pseudouridine synthase activity
EAH50_RS14800	COG4907	membrane protein (DUF2207)
EAH50_RS14805	COG0009	L-threonylcarbamoyladenylate synthase
EAH50_RS14810	COG0613	PHP domain protein
EAH50_RS14820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAH50_RS14825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAH50_RS14825	COG0512	Glutamine amidotransferase of anthranilate synthase
EAH50_RS14830	COG0134	indole-3-glycerol-phosphate synthase activity
EAH50_RS14830	COG0135	phosphoribosylanthranilate isomerase activity
EAH50_RS14845	COG3729	General stress protein
EAH50_RS14850	COG3685	Protein conserved in bacteria
EAH50_RS14855	COG3685	Protein conserved in bacteria
EAH50_RS14860	COG3047	cAMP biosynthetic process
EAH50_RS14880	COG1607	acyl-coa hydrolase
EAH50_RS14885	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EAH50_RS14890	COG2350	Protein conserved in bacteria
EAH50_RS14895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAH50_RS14915	COG4608	Belongs to the ABC transporter superfamily
EAH50_RS14920	COG0444	Belongs to the ABC transporter superfamily
EAH50_RS14925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAH50_RS14930	COG0601	transmembrane transport
EAH50_RS14935	COG4166	transmembrane transport
EAH50_RS14940	COG2095	MarC family integral membrane protein
EAH50_RS14945	COG1454	alcohol dehydrogenase
EAH50_RS14945	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS14955	COG1435	thymidine kinase activity
EAH50_RS14965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAH50_RS14970	COG0745	RESPONSE REGULATOR receiver
EAH50_RS14975	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAH50_RS14985	COG0788	formyltetrahydrofolate deformylase activity
EAH50_RS15010	COG2181	nitrate reductase activity
EAH50_RS15015	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAH50_RS15020	COG1140	nitrate reductase beta subunit
EAH50_RS15025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EAH50_RS15030	COG2223	nitrite transmembrane transporter activity
EAH50_RS15035	COG3850	Histidine kinase
EAH50_RS15040	COG2197	response regulator
EAH50_RS15045	COG4932	domain protein
EAH50_RS15050	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EAH50_RS15055	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EAH50_RS15060	COG4572	Cation transport regulator
EAH50_RS15065	COG0387	Pfam Sodium calcium exchanger
EAH50_RS15090	COG2912	Transglutaminase-like superfamily
EAH50_RS15095	COG3094	Invasion gene expression up-regulator, SirB
EAH50_RS15100	COG2890	protein-(glutamine-N5) methyltransferase activity
EAH50_RS15125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAH50_RS15130	COG0659	secondary active sulfate transmembrane transporter activity
EAH50_RS15145	COG0012	GTP binding
EAH50_RS15150	COG3468	outer membrane autotransporter barrel domain protein
EAH50_RS15155	COG3284	Transcriptional regulator
EAH50_RS15160	COG2376	Dihydroxyacetone kinase
EAH50_RS15165	COG1461	Dihydroxyacetone kinase
EAH50_RS15170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAH50_RS15170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS15170	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EAH50_RS15190	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EAH50_RS15200	COG1619	proteins homologs of microcin C7 resistance protein MccF
EAH50_RS15210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAH50_RS15220	COG2719	SpoVR family
EAH50_RS15235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EAH50_RS15240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAH50_RS15245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAH50_RS15260	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAH50_RS15285	COG2894	cell division
EAH50_RS15330	COG2200	EAL domain
EAH50_RS15360	COG2200	EAL domain
EAH50_RS15365	COG0789	Transcriptional regulator
EAH50_RS15370	COG5562	phage envelope protein
EAH50_RS15385	COG0538	isocitrate dehydrogenase activity
EAH50_RS15390	COG1187	pseudouridine synthase activity
EAH50_RS15410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAH50_RS15420	COG2205	protein histidine kinase activity
EAH50_RS15425	COG2850	peptidyl-arginine hydroxylation
EAH50_RS15445	COG1177	transmembrane transport
EAH50_RS15450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAH50_RS15460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EAH50_RS15465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EAH50_RS15475	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAH50_RS15485	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAH50_RS15490	COG4763	Acyl-transferase
EAH50_RS15495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAH50_RS15500	COG1376	ErfK ybiS ycfS ynhG family protein
EAH50_RS15500	COG1388	LysM domain
EAH50_RS15510	COG1309	transcriptional regulator
EAH50_RS15515	COG3134	Outer membrane lipoprotein
EAH50_RS15520	COG1252	NADH dehydrogenase
EAH50_RS15540	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
EAH50_RS15545	COG5633	Lipoprotein
EAH50_RS15550	COG0537	adenosine 5'-monophosphoramidase activity
EAH50_RS15560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS15560	COG1263	PTS System
EAH50_RS15565	COG0084	hydrolase, TatD family'
EAH50_RS15570	COG0470	DNA polymerase III
EAH50_RS15580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAH50_RS15585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAH50_RS15590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAH50_RS15600	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS15605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EAH50_RS15625	COG1399	metal-binding, possibly nucleic acid-binding protein
EAH50_RS15630	COG0424	maF-like protein
EAH50_RS15635	COG0564	pseudouridine synthase activity
EAH50_RS15645	COG1530	ribonuclease E activity
EAH50_RS15650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EAH50_RS15655	COG1256	bacterial-type flagellum assembly
EAH50_RS15660	COG1705	Flagellar rod assembly protein muramidase FlgJ
EAH50_RS15660	COG3951	Flagellar rod assembly protein muramidase FlgJ
EAH50_RS15675	COG4786	Flagellar basal body rod
EAH50_RS15680	COG4787	bacterial-type flagellum-dependent cell motility
EAH50_RS15685	COG1749	Flagellar hook protein flgE
EAH50_RS15690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EAH50_RS15695	COG1558	bacterial-type flagellum-dependent cell motility
EAH50_RS15700	COG1815	bacterial-type flagellum-dependent cell motility
EAH50_RS15705	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EAH50_RS15710	COG2747	anti-sigma28 factor FlgM
EAH50_RS15715	COG3418	PFAM FlgN family protein
EAH50_RS15720	COG0728	peptidoglycan biosynthetic process
EAH50_RS15725	COG0673	inositol 2-dehydrogenase activity
EAH50_RS15735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAH50_RS15745	COG2999	glutathione oxidoreductase activity
EAH50_RS15780	COG3038	cytochrome b561
EAH50_RS15785	COG2353	YceI-like domain
EAH50_RS15795	COG1560	Kdo2-lipid A biosynthetic process
EAH50_RS15810	COG5645	(Lipo)protein
EAH50_RS15815	COG2943	transferase activity, transferring hexosyl groups
EAH50_RS15830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAH50_RS15835	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EAH50_RS15860	COG2197	response regulator
EAH50_RS15875	COG1462	curli production assembly transport component CsgG
EAH50_RS15885	COG3381	protein complex oligomerization
EAH50_RS15920	COG1702	phosphate starvation-inducible protein PhoH
EAH50_RS15925	COG2837	iron assimilation
EAH50_RS15930	COG2822	iron ion transport
EAH50_RS15940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAH50_RS15950	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAH50_RS15950	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAH50_RS15950	COG0506	proline dehydrogenase activity
EAH50_RS15955	COG1309	transcriptional regulator
EAH50_RS15990	COG2233	PERMEase
EAH50_RS15995	COG3729	General stress protein
EAH50_RS16030	COG3381	protein complex oligomerization
EAH50_RS16035	COG0243	molybdopterin cofactor binding
EAH50_RS16040	COG3005	denitrification pathway
EAH50_RS16045	COG0745	RESPONSE REGULATOR receiver
EAH50_RS16050	COG1879	ABC-type sugar transport system periplasmic component
EAH50_RS16055	COG2205	protein histidine kinase activity
EAH50_RS16055	COG2198	Histidine kinase
EAH50_RS16055	COG0784	Response regulator, receiver
EAH50_RS16060	COG0348	domain, Protein
EAH50_RS16080	COG1278	Cold shock
EAH50_RS16085	COG1278	Cold shock
EAH50_RS16105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAH50_RS16110	COG1596	polysaccharide export
EAH50_RS16115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAH50_RS16120	COG3206	protein involved in exopolysaccharide biosynthesis
EAH50_RS16120	COG0489	protein tyrosine kinase activity
EAH50_RS16135	COG1294	oxidase, subunit
EAH50_RS16140	COG1271	oxidase subunit
EAH50_RS16145	COG1773	rubredoxin
EAH50_RS16150	COG1999	signal sequence binding
EAH50_RS16155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EAH50_RS16160	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
EAH50_RS16165	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EAH50_RS16170	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EAH50_RS16180	COG0670	Belongs to the BI1 family
EAH50_RS16185	COG2920	part of a sulfur-relay system
EAH50_RS16190	COG1254	Belongs to the acylphosphatase family
EAH50_RS16205	COG1832	CoA-binding protein
EAH50_RS16220	COG0210	DNA helicase
EAH50_RS16225	COG3304	Inner membrane component domain
EAH50_RS16230	COG1289	transmembrane transporter activity
EAH50_RS16235	COG3070	regulator of competence-specific genes
EAH50_RS16245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EAH50_RS16245	COG2885	chlorophyll binding
EAH50_RS16255	COG1067	ATP-dependent peptidase activity
EAH50_RS16265	COG3130	regulation of translation
EAH50_RS16270	COG3009	Protein conserved in bacteria
EAH50_RS16275	COG3008	intermembrane lipid transfer
EAH50_RS16275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAH50_RS16280	COG2995	paraquat-inducible protein a
EAH50_RS16285	COG0488	(ABC) transporter
EAH50_RS16295	COG0633	Ferredoxin
EAH50_RS16295	COG3217	Mosc domain protein beta barrel domain protein
EAH50_RS16310	COG3121	Chaperone
EAH50_RS16315	COG3539	Fimbrial protein
EAH50_RS16320	COG3539	Fimbrial protein
EAH50_RS16325	COG3539	Fimbrial protein
EAH50_RS16330	COG3188	usher protein
EAH50_RS16335	COG3121	Chaperone
EAH50_RS16340	COG3539	Fimbrial protein
EAH50_RS16345	COG0431	NADPH-dependent FMN reductase
EAH50_RS16350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAH50_RS16360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAH50_RS16365	COG1116	anion transmembrane transporter activity
EAH50_RS16370	COG0308	aminopeptidase N
EAH50_RS16390	COG1448	Aminotransferase
EAH50_RS16395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAH50_RS16400	COG3108	Peptidase M15
EAH50_RS16405	COG2989	Protein conserved in bacteria
EAH50_RS16415	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EAH50_RS16425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAH50_RS16430	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EAH50_RS16435	COG3173	Aminoglycoside phosphotransferase
EAH50_RS16450	COG3214	Protein conserved in bacteria
EAH50_RS16460	COG1132	(ABC) transporter
EAH50_RS16465	COG2333	competence protein COMEC
EAH50_RS16465	COG0658	competence protein
EAH50_RS16475	COG0539	negative regulation of cytoplasmic translation
EAH50_RS16500	COG2323	membrane
EAH50_RS16505	COG1944	ATP diphosphatase activity
EAH50_RS16510	COG2116	formate transmembrane transporter activity
EAH50_RS16515	COG1882	Formate acetyltransferase
EAH50_RS16520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAH50_RS16525	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAH50_RS16530	COG0583	DNA-binding transcription factor activity
EAH50_RS16535	COG0531	amino acid
EAH50_RS16545	COG1335	isochorismatase
EAH50_RS16550	COG3302	dmso reductase anchor subunit
EAH50_RS16555	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS16560	COG0243	molybdopterin cofactor binding
EAH50_RS16570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAH50_RS16580	COG1674	ftsk spoiiie
EAH50_RS16580	COG1178	ABC-type Fe3 transport system permease component
EAH50_RS16585	COG1522	sequence-specific DNA binding
EAH50_RS16590	COG0492	ferredoxin-NADP+ reductase activity
EAH50_RS16595	COG4988	ABC transporter
EAH50_RS16600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EAH50_RS16625	COG0542	response to heat
EAH50_RS16635	COG1278	Cold shock
EAH50_RS16640	COG1136	(ABC) transporter
EAH50_RS16640	COG0577	efflux transmembrane transporter activity
EAH50_RS16645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS16650	COG2990	Protein conserved in bacteria
EAH50_RS16655	COG3593	DNA synthesis involved in DNA repair
EAH50_RS16665	COG2431	L-lysine efflux transmembrane transporter activity
EAH50_RS16675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAH50_RS16680	COG0028	Belongs to the TPP enzyme family
EAH50_RS16685	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EAH50_RS16690	COG0702	epimerase
EAH50_RS16695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAH50_RS16700	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAH50_RS16715	COG1126	abc transporter atp-binding protein
EAH50_RS16720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS16725	COG4215	(ABC) transporter
EAH50_RS16730	COG4160	amino acid transport
EAH50_RS16735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS16750	COG1177	transmembrane transport
EAH50_RS16755	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAH50_RS16760	COG3842	ATPase activity
EAH50_RS16765	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAH50_RS16790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAH50_RS16805	COG3226	Transcriptional regulator
EAH50_RS16810	COG0738	Major facilitator superfamily
EAH50_RS16815	COG0561	phosphatase activity
EAH50_RS16825	COG2814	Major facilitator Superfamily
EAH50_RS16830	COG0671	phosphoesterase, PA-phosphatase related
EAH50_RS16835	COG1349	DNA-binding transcription factor activity
EAH50_RS16840	COG1686	Belongs to the peptidase S11 family
EAH50_RS16845	COG0625	glutathione transferase activity
EAH50_RS16850	COG2133	pyrroloquinoline quinone binding
EAH50_RS16865	COG2199	diguanylate cyclase activity
EAH50_RS16870	COG2200	EAL domain
EAH50_RS16875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAH50_RS16885	COG0747	negative chemotaxis
EAH50_RS16895	COG1446	asparaginase
EAH50_RS16900	COG0303	'Molybdopterin
EAH50_RS16905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EAH50_RS16910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAH50_RS16915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAH50_RS16920	COG1882	Formate acetyltransferase
EAH50_RS16925	COG0561	phosphatase activity
EAH50_RS16935	COG0488	(ABC) transporter
EAH50_RS16940	COG1376	ErfK ybiS ycfS ynhG family protein
EAH50_RS16945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EAH50_RS16950	COG1321	iron dependent repressor
EAH50_RS16960	COG2194	sulfuric ester hydrolase activity
EAH50_RS16965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EAH50_RS16975	COG5006	permease, DMT superfamily
EAH50_RS16985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS16990	COG0765	amino acid transport
EAH50_RS16995	COG1126	abc transporter atp-binding protein
EAH50_RS17000	COG0668	transmembrane transport
EAH50_RS17015	COG4774	siderophore transport
EAH50_RS17025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAH50_RS17035	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EAH50_RS17040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAH50_RS17045	COG1199	ATP-dependent helicase activity
EAH50_RS17050	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EAH50_RS17055	COG0513	Belongs to the DEAD box helicase family
EAH50_RS17060	COG1309	transcriptional regulator
EAH50_RS17070	COG1131	(ABC) transporter
EAH50_RS17075	COG0842	Transport permease protein
EAH50_RS17080	COG0842	Transport permease protein
EAH50_RS17090	COG3568	Endonuclease Exonuclease Phosphatase
EAH50_RS17095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAH50_RS17100	COG0392	lysyltransferase activity
EAH50_RS17105	COG0670	Belongs to the BI1 family
EAH50_RS17110	COG0670	Belongs to the BI1 family
EAH50_RS17115	COG0314	molybdopterin synthase activity
EAH50_RS17120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EAH50_RS17130	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAH50_RS17140	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EAH50_RS17150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EAH50_RS17155	COG2226	methyltransferase
EAH50_RS17170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EAH50_RS17175	COG1881	PFAM PEBP family protein
EAH50_RS17180	COG2199	diguanylate cyclase activity
EAH50_RS17185	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EAH50_RS17190	COG5301	cellulose 1,4-beta-cellobiosidase activity
EAH50_RS17235	COG1196	nuclear chromosome segregation
EAH50_RS17285	COG1030	water channel activity
EAH50_RS17305	COG4220	transposase activity
EAH50_RS17315	COG5562	phage envelope protein
EAH50_RS17320	COG3646	Phage regulatory protein
EAH50_RS17335	COG3772	lysozyme
EAH50_RS17525	COG0582	viral genome integration into host DNA
EAH50_RS17530	COG4677	pectinesterase activity
EAH50_RS17535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAH50_RS17540	COG0471	metal ion transport
EAH50_RS17545	COG2828	Protein conserved in bacteria
EAH50_RS17550	COG0583	DNA-binding transcription factor activity
EAH50_RS17560	COG0561	phosphatase activity
EAH50_RS17565	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EAH50_RS17570	COG4149	molybdate abc transporter
EAH50_RS17575	COG0725	ABC transporter, periplasmic molybdate-binding protein
EAH50_RS17585	COG2005	Transcriptional regulator
EAH50_RS17585	COG3585	molybdate ion transport
EAH50_RS17590	COG1119	ATPase activity
EAH50_RS17595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAH50_RS17600	COG1085	galactose-1-phosphate uridylyltransferase
EAH50_RS17610	COG2017	converts alpha-aldose to the beta-anomer
EAH50_RS17620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAH50_RS17630	COG1230	cation diffusion facilitator family transporter
EAH50_RS17635	COG3201	nicotinamide mononucleotide transporter
EAH50_RS17670	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EAH50_RS17675	COG2885	chlorophyll binding
EAH50_RS17685	COG3064	Membrane
EAH50_RS17690	COG0848	biopolymer transport protein
EAH50_RS17695	COG0811	peptide transport
EAH50_RS17700	COG0824	Thioesterase
EAH50_RS17705	COG3790	cyd operon protein YbgE
EAH50_RS17710	COG4890	Cyd operon protein YbgT
EAH50_RS17715	COG1294	oxidase, subunit
EAH50_RS17720	COG1271	oxidase subunit
EAH50_RS17730	COG0383	alpha-mannosidase activity
EAH50_RS17735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS17735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS17735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS17740	COG2188	Transcriptional regulator
EAH50_RS17745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAH50_RS17755	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAH50_RS17760	COG0567	Dehydrogenase, E1 component
EAH50_RS17765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAH50_RS17770	COG1053	succinate dehydrogenase
EAH50_RS17775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EAH50_RS17780	COG2009	succinate dehydrogenase
EAH50_RS17790	COG0372	Belongs to the citrate synthase family
EAH50_RS17795	COG3539	Fimbrial protein
EAH50_RS17800	COG3188	usher protein
EAH50_RS17805	COG3121	Chaperone
EAH50_RS17810	COG3539	Fimbrial protein
EAH50_RS17815	COG3180	Ammonia monooxygenase
EAH50_RS17830	COG1984	allophanate hydrolase subunit 2
EAH50_RS17835	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EAH50_RS17840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAH50_RS17845	COG3104	oligopeptide transport
EAH50_RS17850	COG0415	Belongs to the DNA photolyase family
EAH50_RS17855	COG3272	Protein of unknown function (DUF1722)
EAH50_RS17905	COG3209	COG3209 Rhs family protein
EAH50_RS17935	COG2205	protein histidine kinase activity
EAH50_RS17940	COG0745	RESPONSE REGULATOR receiver
EAH50_RS17955	COG1982	Orn Lys Arg decarboxylase major
EAH50_RS17960	COG0531	amino acid
EAH50_RS17980	COG0033	Phosphoglucomutase
EAH50_RS17985	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EAH50_RS17990	COG0596	Alpha beta hydrolase
EAH50_RS18000	COG0716	FMN binding
EAH50_RS18010	COG0735	belongs to the Fur family
EAH50_RS18035	COG1263	PTS System
EAH50_RS18035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS18035	COG2190	(PTS) system
EAH50_RS18045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAH50_RS18050	COG1846	Transcriptional regulator
EAH50_RS18050	COG1940	carbohydrate kinase activity
EAH50_RS18055	COG0647	UMP catabolic process
EAH50_RS18060	COG0367	asparagine synthase
EAH50_RS18100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAH50_RS18110	COG1702	phosphate starvation-inducible protein PhoH
EAH50_RS18120	COG4535	Mg2 and Co2 transporter CorC
EAH50_RS18125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EAH50_RS18130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAH50_RS18135	COG0765	amino acid transport
EAH50_RS18140	COG0765	amino acid transport
EAH50_RS18145	COG1126	abc transporter atp-binding protein
EAH50_RS18155	COG0443	Heat shock 70 kDa protein
EAH50_RS18160	COG2214	Heat shock protein DnaJ domain protein
EAH50_RS18170	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAH50_RS18185	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAH50_RS18190	COG2888	peptidyl-tyrosine sulfation
EAH50_RS18205	COG1466	dna polymerase III delta subunit
EAH50_RS18215	COG0406	alpha-ribazole phosphatase activity
EAH50_RS18220	COG0799	negative regulation of ribosome biogenesis
EAH50_RS18230	COG0768	penicillin binding
EAH50_RS18235	COG0772	Belongs to the SEDS family
EAH50_RS18240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAH50_RS18245	COG1686	Belongs to the peptidase S11 family
EAH50_RS18270	COG0583	DNA-binding transcription factor activity
EAH50_RS18280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAH50_RS18285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAH50_RS18305	COG3069	C4-dicarboxylate transmembrane transporter activity
EAH50_RS18310	COG4565	transcriptional regulatory protein
EAH50_RS18315	COG3290	protein histidine kinase activity
EAH50_RS18320	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EAH50_RS18330	COG2301	Belongs to the HpcH HpaI aldolase family
EAH50_RS18335	COG3051	citrate lyase alpha subunit
EAH50_RS18350	COG0471	metal ion transport
EAH50_RS18355	COG3719	Belongs to the RNase T2 family
EAH50_RS18360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAH50_RS18365	COG1063	alcohol dehydrogenase
EAH50_RS18370	COG0589	response to stress
EAH50_RS18375	COG3634	alkyl hydroperoxide reductase activity
EAH50_RS18380	COG0450	alkyl hydroperoxide reductase
EAH50_RS18385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAH50_RS18390	COG0583	DNA-binding transcription factor activity
EAH50_RS18395	COG3969	phosphoadenosine phosphosulfate
EAH50_RS18400	COG1475	DNA binding
EAH50_RS18405	COG0436	Aminotransferase
EAH50_RS18410	COG0371	Dehydrogenase
EAH50_RS18415	COG2879	small protein
EAH50_RS18420	COG1966	Carbon starvation protein
EAH50_RS18425	COG2050	protein possibly involved in aromatic compounds catabolism
EAH50_RS18430	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS18435	COG3433	isochorismatase activity
EAH50_RS18435	COG1535	isochorismatase
EAH50_RS18440	COG1021	2,3-dihydroxybenzoate-AMP ligase
EAH50_RS18445	COG1169	isochorismate synthase
EAH50_RS18450	COG4592	Periplasmic binding protein
EAH50_RS18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAH50_RS18465	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAH50_RS18470	COG1120	ATPase activity
EAH50_RS18490	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EAH50_RS18490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAH50_RS18495	COG3251	PFAM MbtH domain protein
EAH50_RS18500	COG2382	esterase
EAH50_RS18505	COG4771	TonB-dependent receptor
EAH50_RS18510	COG2977	Belongs to the P-Pant transferase superfamily
EAH50_RS18515	COG3385	transposase activity
EAH50_RS18545	COG2315	Protein conserved in bacteria
EAH50_RS18550	COG0778	Nitroreductase
EAH50_RS18555	COG0668	transmembrane transport
EAH50_RS18560	COG1113	amino acid transport
EAH50_RS18565	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAH50_RS18570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS18575	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS18590	COG1538	Outer membrane efflux protein
EAH50_RS18595	COG0745	RESPONSE REGULATOR receiver
EAH50_RS18600	COG5002	protein histidine kinase activity
EAH50_RS18605	COG3501	Rhs element vgr protein
EAH50_RS18620	COG5433	transposase activity
EAH50_RS18625	COG1215	transferase activity, transferring glycosyl groups
EAH50_RS18630	COG4783	chaperone-mediated protein folding
EAH50_RS18640	COG2207	Transcriptional regulator
EAH50_RS18650	COG2197	response regulator
EAH50_RS18655	COG3539	Fimbrial protein
EAH50_RS18660	COG3539	Fimbrial protein
EAH50_RS18680	COG3121	Chaperone
EAH50_RS18685	COG3539	Fimbrial protein
EAH50_RS18695	COG2501	S4 domain
EAH50_RS18700	COG1988	membrane-bound metal-dependent
EAH50_RS18710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAH50_RS18720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EAH50_RS18725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAH50_RS18730	COG0549	Belongs to the carbamate kinase family
EAH50_RS18740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAH50_RS18745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAH50_RS18760	COG1929	Belongs to the glycerate kinase type-1 family
EAH50_RS18765	COG2233	PERMEase
EAH50_RS18775	COG1953	Uracil, thiamine, allantoin
EAH50_RS18780	COG2084	Dehydrogenase
EAH50_RS18785	COG3622	Belongs to the hyi family
EAH50_RS18790	COG3960	tartronate-semialdehyde synthase activity
EAH50_RS18795	COG1414	Transcriptional regulator
EAH50_RS18805	COG0583	DNA-binding transcription factor activity
EAH50_RS18845	COG3209	COG3209 Rhs family protein
EAH50_RS18850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAH50_RS18855	COG4181	ATPase activity
EAH50_RS18860	COG2755	lipolytic protein G-D-S-L family
EAH50_RS18865	COG0300	oxidoreductase activity
EAH50_RS18870	COG3118	belongs to the thioredoxin family
EAH50_RS18875	COG0390	transport system, permease component
EAH50_RS18880	COG4619	ABC transporter
EAH50_RS18885	COG0330	HflC and HflK could
EAH50_RS18890	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAH50_RS18895	COG0789	Transcriptional regulator
EAH50_RS18900	COG0531	amino acid
EAH50_RS18905	COG2066	Belongs to the glutaminase family
EAH50_RS18910	COG2217	Heavy metal translocating P-type atpase
EAH50_RS18915	COG3093	addiction module antidote protein HigA
EAH50_RS18925	COG3735	TraB family
EAH50_RS18930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAH50_RS18935	COG0737	Belongs to the 5'-nucleotidase family
EAH50_RS18940	COG2223	nitrite transmembrane transporter activity
EAH50_RS18945	COG4651	solute:proton antiporter activity
EAH50_RS18945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAH50_RS18950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS18985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAH50_RS18995	COG2832	Protein of unknown function (DUF454)
EAH50_RS19000	COG3923	Primosomal replication protein n
EAH50_RS19010	COG3264	Mechanosensitive ion channel
EAH50_RS19010	COG1196	nuclear chromosome segregation
EAH50_RS19020	COG2826	transposase and inactivated derivatives, IS30 family
EAH50_RS19025	COG1309	transcriptional regulator
EAH50_RS19030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAH50_RS19035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAH50_RS19050	COG0110	maltose O-acetyltransferase activity
EAH50_RS19060	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAH50_RS19065	COG5507	3-demethylubiquinone-9 3-methyltransferase
EAH50_RS19075	COG3695	enzyme binding
EAH50_RS19080	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EAH50_RS19085	COG1946	Acyl-CoA thioesterase
EAH50_RS19090	COG0004	ammonium transporteR
EAH50_RS19095	COG0347	Belongs to the P(II) protein family
EAH50_RS19100	COG1132	(ABC) transporter
EAH50_RS19105	COG1132	(ABC) transporter
EAH50_RS19110	COG1522	sequence-specific DNA binding
EAH50_RS19120	COG4533	DNA binding
EAH50_RS19130	COG0824	Thioesterase
EAH50_RS19135	COG1555	photosystem II stabilization
EAH50_RS19140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAH50_RS19145	COG0776	regulation of translation
EAH50_RS19150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAH50_RS19175	COG0271	Belongs to the BolA IbaG family
EAH50_RS19180	COG3056	Lipoprotein
EAH50_RS19185	COG2223	nitrite transmembrane transporter activity
EAH50_RS19190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EAH50_RS19195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAH50_RS19200	COG1845	cytochrome c oxidase, subunit III
EAH50_RS19205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAH50_RS19215	COG2814	Major facilitator Superfamily
EAH50_RS19225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAH50_RS19230	COG0693	protein deglycase activity
EAH50_RS19245	COG0142	geranyltranstransferase activity
EAH50_RS19260	COG0667	Aldo Keto reductase
EAH50_RS19265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAH50_RS19270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EAH50_RS19285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAH50_RS19285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAH50_RS19295	COG4238	major outer membrane lipoprotein
EAH50_RS19300	COG3248	Nucleoside-binding outer membrane protein
EAH50_RS19305	COG1403	HNH endonuclease
EAH50_RS19310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAH50_RS19315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAH50_RS19320	COG1862	Preprotein translocase
EAH50_RS19340	COG0366	Alpha amylase catalytic
EAH50_RS19345	COG1113	amino acid transport
EAH50_RS19350	COG1114	Component of the transport system for branched-chain amino acids
EAH50_RS19360	COG5002	protein histidine kinase activity
EAH50_RS19365	COG0745	RESPONSE REGULATOR receiver
EAH50_RS19370	COG0420	3'-5' exonuclease activity
EAH50_RS19375	COG0419	ATPase involved in DNA repair
EAH50_RS19380	COG2814	Major facilitator Superfamily
EAH50_RS19385	COG1940	carbohydrate kinase activity
EAH50_RS19410	COG4126	flavin adenine dinucleotide binding
EAH50_RS19430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EAH50_RS19435	COG3706	GGDEF domain
EAH50_RS19445	COG1785	Belongs to the alkaline phosphatase family
EAH50_RS19455	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAH50_RS19475	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EAH50_RS19480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAH50_RS19485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAH50_RS19490	COG3468	outer membrane autotransporter barrel domain protein
EAH50_RS19495	COG0113	porphobilinogen synthase activity
EAH50_RS19500	COG2175	clavaminate synthase activity
EAH50_RS19505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAH50_RS19515	COG4521	taurine ABC transporter
EAH50_RS19520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EAH50_RS19525	COG1215	transferase activity, transferring glycosyl groups
EAH50_RS19555	COG3122	Protein conserved in bacteria
EAH50_RS19560	COG2814	Major facilitator Superfamily
EAH50_RS19595	COG1414	Transcriptional regulator
EAH50_RS19600	COG1609	Transcriptional regulator
EAH50_RS19605	COG3250	beta-galactosidase activity
EAH50_RS19610	COG2223	nitrite transmembrane transporter activity
EAH50_RS19615	COG0110	maltose O-acetyltransferase activity
EAH50_RS19620	COG2807	transmembrane transport
EAH50_RS19630	COG0288	reversible hydration of carbon dioxide
EAH50_RS19635	COG0583	DNA-binding transcription factor activity
EAH50_RS19640	COG0402	S-adenosylhomocysteine deaminase activity
EAH50_RS19645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EAH50_RS19650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAH50_RS19655	COG2079	MmgE PrpD family protein
EAH50_RS19660	COG0372	Belongs to the citrate synthase family
EAH50_RS19665	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EAH50_RS19670	COG3829	transcription factor binding
EAH50_RS19680	COG1280	lysine exporter protein (LysE YggA)
EAH50_RS19705	COG1064	alcohol dehydrogenase
EAH50_RS19710	COG0402	S-adenosylhomocysteine deaminase activity
EAH50_RS19715	COG0549	Belongs to the carbamate kinase family
EAH50_RS19725	COG1304	FMN binding
EAH50_RS19730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAH50_RS19740	COG0666	response to abiotic stimulus
EAH50_RS19750	COG0583	DNA-binding transcription factor activity
EAH50_RS19755	COG2200	EAL domain
EAH50_RS19755	COG2771	luxR family
EAH50_RS19765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAH50_RS19845	COG3121	Chaperone
EAH50_RS19850	COG0727	PFAM Uncharacterised protein family (UPF0153)
EAH50_RS19860	COG3477	response to acidic pH
EAH50_RS19865	COG2080	2 iron, 2 sulfur cluster binding
EAH50_RS19870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EAH50_RS19880	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EAH50_RS19885	COG0583	DNA-binding transcription factor activity
EAH50_RS20000	COG0582	viral genome integration into host DNA
EAH50_RS20025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAH50_RS20045	COG2195	Cleaves the N-terminal amino acid of tripeptides
EAH50_RS20050	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EAH50_RS20055	COG1690	Belongs to the RtcB family
EAH50_RS20060	COG0454	-acetyltransferase
EAH50_RS20070	COG2161	toxin-antitoxin pair type II binding
EAH50_RS20090	COG1943	Transposase
EAH50_RS20095	COG0791	NLP P60 protein
EAH50_RS20100	COG3077	Addiction module antitoxin, RelB DinJ family
EAH50_RS20105	COG3041	Addiction module toxin RelE StbE family
EAH50_RS20110	COG3034	peptidoglycan biosynthetic process
EAH50_RS20115	COG0121	glutamine amidotransferase
EAH50_RS20125	COG1960	acyl-CoA dehydrogenase activity
EAH50_RS20135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAH50_RS20255	COG3157	Type VI secretion system effector, Hcp
EAH50_RS20260	COG4104	PAAR repeat-containing protein
EAH50_RS20280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAH50_RS20290	COG2226	methyltransferase
EAH50_RS20300	COG1388	LysM domain
EAH50_RS20300	COG0741	lytic transglycosylase activity
EAH50_RS20305	COG2226	methyltransferase
EAH50_RS20315	COG0583	DNA-binding transcription factor activity
EAH50_RS20355	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAH50_RS20360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAH50_RS20365	COG2011	ABC-type metal ion transport system permease component
EAH50_RS20370	COG1464	Belongs to the NlpA lipoprotein family
EAH50_RS20380	COG1720	tRNA m6t6A37 methyltransferase activity
EAH50_RS20390	COG0791	NLP P60 protein
EAH50_RS20410	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EAH50_RS20415	COG4681	YaeQ
EAH50_RS20425	COG4568	rho-dependent transcription termination
EAH50_RS20430	COG0037	tRNA processing
EAH50_RS20435	COG0346	lactoylglutathione lyase activity
EAH50_RS20440	COG1982	Orn Lys Arg decarboxylase major
EAH50_RS20450	COG0587	DNA-directed DNA polymerase activity
EAH50_RS20475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAH50_RS20480	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EAH50_RS20490	COG0750	zinc metalloprotease
EAH50_RS20495	COG0575	Belongs to the CDS family
EAH50_RS20500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EAH50_RS20505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EAH50_RS20530	COG0024	Methionine aminopeptidase
EAH50_RS20550	COG3835	regulator
EAH50_RS20555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAH50_RS20570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAH50_RS20575	COG2860	membrane
EAH50_RS20600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAH50_RS20605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAH50_RS20610	COG1120	ATPase activity
EAH50_RS20615	COG4774	siderophore transport
EAH50_RS20620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAH50_RS20625	COG1643	Atp-dependent helicase
EAH50_RS20630	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EAH50_RS20640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAH50_RS20645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAH50_RS20650	COG0617	tRNA 3'-terminal CCA addition
EAH50_RS20655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EAH50_RS20660	COG3539	Fimbrial protein
EAH50_RS20665	COG3121	Chaperone
EAH50_RS20670	COG3188	usher protein
EAH50_RS20675	COG3539	Fimbrial protein
EAH50_RS20680	COG3539	Fimbrial protein
EAH50_RS20685	COG3539	Fimbrial protein
EAH50_RS20690	COG3539	Fimbrial protein
EAH50_RS20710	COG5464	transposase or invertase
EAH50_RS20720	COG0726	polysaccharide deacetylase
EAH50_RS20725	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS20730	COG0842	Transport permease protein
EAH50_RS20735	COG1131	(ABC) transporter
EAH50_RS20740	COG0288	reversible hydration of carbon dioxide
EAH50_RS20745	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EAH50_RS20750	COG4993	Dehydrogenase
EAH50_RS20755	COG2132	Multicopper oxidase
EAH50_RS20780	COG1049	propionate catabolic process, 2-methylcitrate cycle
EAH50_RS20785	COG3064	Membrane
EAH50_RS20790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAH50_RS20795	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAH50_RS20800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EAH50_RS20805	COG2186	Transcriptional regulator
EAH50_RS20810	COG1113	amino acid transport
EAH50_RS20815	COG3725	Membrane protein required for beta-lactamase induction
EAH50_RS20820	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAH50_RS20825	COG0157	Belongs to the NadC ModD family
EAH50_RS20830	COG4969	Belongs to the N-Me-Phe pilin family
EAH50_RS20835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAH50_RS20840	COG1459	type II secretion system
EAH50_RS20850	COG0237	dephospho-CoA kinase activity
EAH50_RS20865	COG0494	nUDIX hydrolase
EAH50_RS20885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAH50_RS20890	COG0849	cell division
EAH50_RS20895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EAH50_RS20900	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAH50_RS20915	COG0772	Belongs to the SEDS family
EAH50_RS20920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EAH50_RS20930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAH50_RS20935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAH50_RS20940	COG0768	penicillin binding
EAH50_RS20945	COG3116	cell division
EAH50_RS20960	COG1609	Transcriptional regulator
EAH50_RS20970	COG0440	acetolactate synthase activity
EAH50_RS20975	COG0028	Belongs to the TPP enzyme family
EAH50_RS20985	COG0583	DNA-binding transcription factor activity
EAH50_RS21000	COG0473	3-isopropylmalate dehydrogenase activity
EAH50_RS21015	COG2814	Major facilitator Superfamily
EAH50_RS21030	COG4143	(ABC) transporter
EAH50_RS21035	COG1178	ABC-type Fe3 transport system permease component
EAH50_RS21045	COG0586	Pfam SNARE associated Golgi protein
EAH50_RS21050	COG4977	sequence-specific DNA binding
EAH50_RS21065	COG0235	Class ii aldolase
EAH50_RS21070	COG0417	DNA replication proofreading
EAH50_RS21080	COG0564	pseudouridine synthase activity
EAH50_RS21085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EAH50_RS21090	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EAH50_RS21095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAH50_RS21120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EAH50_RS21135	COG2271	Major facilitator Superfamily
EAH50_RS21140	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EAH50_RS21145	COG0644	oxidoreductase
EAH50_RS21205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EAH50_RS21210	COG0505	Belongs to the CarA family
EAH50_RS21230	COG1047	Peptidyl-prolyl cis-trans
EAH50_RS21245	COG0196	riboflavin kinase activity
EAH50_RS21275	COG0583	DNA-binding transcription factor activity
EAH50_RS21290	COG3385	transposase activity
EAH50_RS21310	COG4735	regulation of single-species biofilm formation
EAH50_RS21315	COG1584	GPR1 FUN34 yaaH family protein
EAH50_RS21320	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAH50_RS21330	COG1115	amino acid carrier protein
EAH50_RS21345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EAH50_RS21355	COG0460	homoserine dehydrogenase
EAH50_RS21355	COG0527	aspartate kinase activity
EAH50_RS21365	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EAH50_RS21375	COG0745	RESPONSE REGULATOR receiver
EAH50_RS21380	COG4452	Inner membrane protein CreD
EAH50_RS21385	COG2205	protein histidine kinase activity
EAH50_RS21390	COG0745	RESPONSE REGULATOR receiver
EAH50_RS21395	COG3045	CreA protein
EAH50_RS21400	COG3708	Transcriptional regulator
EAH50_RS21400	COG2207	Transcriptional regulator
EAH50_RS21420	COG0741	lytic transglycosylase activity
EAH50_RS21425	COG0488	(ABC) transporter
EAH50_RS21430	COG1056	cytidyltransferase-related domain
EAH50_RS21430	COG3172	ATPase kinase involved in NAD metabolism
EAH50_RS21435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EAH50_RS21440	COG0560	Phosphoserine phosphatase
EAH50_RS21445	COG3726	membrane protein affecting hemolysin expression
EAH50_RS21480	COG1328	CTP reductase activity
EAH50_RS21485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAH50_RS21490	COG0084	hydrolase, TatD family'
EAH50_RS21495	COG4667	esterase of the alpha-beta hydrolase superfamily
EAH50_RS21505	COG2823	Periplasmic or secreted lipoprotein
EAH50_RS21515	COG1011	Hydrolase
EAH50_RS21520	COG0456	acetyltransferase
EAH50_RS21525	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EAH50_RS21555	COG4114	ferric iron reductase
EAH50_RS21560	COG2197	response regulator
EAH50_RS21565	COG2197	response regulator
EAH50_RS21575	COG2966	Psort location CytoplasmicMembrane, score
EAH50_RS21590	COG1484	DNA-dependent DNA replication
EAH50_RS21605	COG1063	alcohol dehydrogenase
EAH50_RS21610	COG1802	Transcriptional regulator
EAH50_RS21615	COG0025	NhaP-type Na H and K H
EAH50_RS21620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAH50_RS21630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAH50_RS21635	COG0840	transmembrane signaling receptor activity
EAH50_RS21640	COG1846	Transcriptional regulator
EAH50_RS21645	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAH50_RS21650	COG1012	belongs to the aldehyde dehydrogenase family
EAH50_RS21655	COG3384	dioxygenase
EAH50_RS21665	COG3971	2-oxopent-4-enoate hydratase activity
EAH50_RS21685	COG2368	4-hydroxyphenylacetate
EAH50_RS21690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAH50_RS21695	COG1966	Carbon starvation protein
EAH50_RS21700	COG2879	small protein
EAH50_RS21705	COG0523	cobalamin synthesis protein
EAH50_RS21715	COG5457	Domain of unknown function (DUF1127)
EAH50_RS21720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAH50_RS21735	COG2814	Major facilitator Superfamily
EAH50_RS21740	COG2733	membrane
EAH50_RS21745	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EAH50_RS21750	COG1924	4 iron, 4 sulfur cluster binding
EAH50_RS21765	COG0477	Major facilitator Superfamily
EAH50_RS21775	COG3366	ferrous iron transmembrane transporter activity
EAH50_RS21780	COG0700	Nucleoside recognition
EAH50_RS21785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAH50_RS21790	COG0583	DNA-binding transcription factor activity
EAH50_RS21815	COG2186	Transcriptional regulator
EAH50_RS21825	COG0246	Mannitol dehydrogenase
EAH50_RS21840	COG3539	Fimbrial protein
EAH50_RS21845	COG3539	Fimbrial protein
EAH50_RS21855	COG3188	usher protein
EAH50_RS21865	COG0582	viral genome integration into host DNA
EAH50_RS21875	COG1064	alcohol dehydrogenase
EAH50_RS21880	COG0433	COG0433 Predicted ATPase
EAH50_RS21885	COG0795	lipopolysaccharide-transporting ATPase activity
EAH50_RS21890	COG0795	lipopolysaccharide-transporting ATPase activity
EAH50_RS21900	COG2927	DNA polymerase III (CHI subunit)
EAH50_RS21910	COG4269	membrane
EAH50_RS21915	COG0456	acetyltransferase
EAH50_RS21920	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EAH50_RS21940	COG2731	YhcH YjgK YiaL family protein
EAH50_RS21945	COG1309	transcriptional regulator
EAH50_RS21950	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS21955	COG0251	oxidation-reduction process
EAH50_RS21975	COG0251	oxidation-reduction process
EAH50_RS21980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EAH50_RS21990	COG1609	Transcriptional regulator
EAH50_RS21995	COG1263	PTS System
EAH50_RS21995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAH50_RS22000	COG0366	Alpha amylase catalytic
EAH50_RS22005	COG1328	CTP reductase activity
EAH50_RS22010	COG0602	queuosine metabolic process
EAH50_RS22015	COG3783	Cytochrome b(562)
EAH50_RS22020	COG0312	modulator of DNA gyrase
EAH50_RS22030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAH50_RS22040	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS22045	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS22050	COG1129	ABC transporter
EAH50_RS22055	COG1879	ABC-type sugar transport system periplasmic component
EAH50_RS22060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EAH50_RS22070	COG2105	PFAM AIG2 family protein
EAH50_RS22075	COG2911	Protein conserved in bacteria
EAH50_RS22080	COG0729	surface antigen
EAH50_RS22090	COG1253	flavin adenine dinucleotide binding
EAH50_RS22100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EAH50_RS22105	COG1218	3'(2'),5'-bisphosphate nucleotidase
EAH50_RS22115	COG1733	regulation of RNA biosynthetic process
EAH50_RS22120	COG0702	epimerase
EAH50_RS22125	COG0697	spore germination
EAH50_RS22135	COG1113	amino acid transport
EAH50_RS22140	COG0545	Peptidyl-prolyl cis-trans isomerase
EAH50_RS22150	COG3061	Opacity-associated protein A
EAH50_RS22155	COG1309	transcriptional regulator
EAH50_RS22160	COG1028	Short-chain dehydrogenase reductase Sdr
EAH50_RS22170	COG1024	Enoyl-CoA hydratase
EAH50_RS22175	COG4670	ketone body catabolic process
EAH50_RS22180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAH50_RS22185	COG2271	Major facilitator Superfamily
EAH50_RS22195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EAH50_RS22235	COG3414	Phosphotransferase system galactitol-specific IIB component
EAH50_RS22240	COG3037	sugar-specific permease SgaT UlaA
EAH50_RS22255	COG1073	alpha beta
EAH50_RS22260	COG3650	response to hydrogen peroxide
EAH50_RS22270	COG1960	acyl-CoA dehydrogenase activity
EAH50_RS22275	COG0754	glutathionylspermidine amidase activity
EAH50_RS22280	COG5463	Belongs to the UPF0441 family
EAH50_RS22285	COG3766	membrane
EAH50_RS22295	COG1842	Phage shock protein A
EAH50_RS22300	COG3789	protein conserved in bacteria
EAH50_RS22305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAH50_RS22310	COG0557	exoribonuclease II activity
EAH50_RS22325	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EAH50_RS22330	COG0330	HflC and HflK could
EAH50_RS22335	COG0330	HflC and HflK could
EAH50_RS22340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAH50_RS22360	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAH50_RS22365	COG0802	atpase or kinase
EAH50_RS22370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAH50_RS22370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAH50_RS22375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAH50_RS22415	COG1511	domain protein
EAH50_RS22415	COG3264	Mechanosensitive ion channel
EAH50_RS22420	COG0531	amino acid
EAH50_RS22430	COG1053	succinate dehydrogenase
EAH50_RS22435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAH50_RS22450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAH50_RS22455	COG3040	lipid binding
EAH50_RS22460	COG2076	Multidrug Resistance protein
EAH50_RS22465	COG5510	response to toxic substance
EAH50_RS22470	COG5510	response to toxic substance
EAH50_RS22480	COG1509	lysine 2,3-aminomutase activity
EAH50_RS22505	COG0531	amino acid
EAH50_RS22510	COG3030	protein affecting phage T7 exclusion by the F plasmid
EAH50_RS22515	COG1027	Aspartate ammonia-lyase
EAH50_RS22520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EAH50_RS22535	COG1309	transcriptional regulator
EAH50_RS22545	COG3710	Transcriptional regulator
EAH50_RS22555	COG0531	amino acid
EAH50_RS22560	COG1982	Orn Lys Arg decarboxylase major
EAH50_RS22565	COG3104	oligopeptide transport
EAH50_RS22570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EAH50_RS22585	COG2388	GCN5-related N-acetyl-transferase
EAH50_RS22590	COG3592	Divergent 4Fe-4S mono-cluster
EAH50_RS22595	COG3290	protein histidine kinase activity
EAH50_RS22600	COG4565	transcriptional regulatory protein
EAH50_RS22605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EAH50_RS22610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAH50_RS22610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAH50_RS22615	COG3647	Membrane
EAH50_RS22620	COG2211	Major facilitator Superfamily
EAH50_RS22625	COG1486	melibiose metabolic process
EAH50_RS22630	COG2169	Transcriptional regulator
EAH50_RS22635	COG1982	Orn Lys Arg decarboxylase major
EAH50_RS22640	COG2207	Transcriptional regulator
EAH50_RS22645	COG0531	amino acid
EAH50_RS22650	COG2194	sulfuric ester hydrolase activity
EAH50_RS22655	COG0745	RESPONSE REGULATOR receiver
EAH50_RS22660	COG0642	Histidine kinase
EAH50_RS22670	COG0477	Major facilitator Superfamily
EAH50_RS22685	COG2824	Alkylphosphonate utilization operon protein PhnA
EAH50_RS22690	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EAH50_RS22695	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EAH50_RS22700	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EAH50_RS22705	COG3639	organic phosphonate transmembrane transporter activity
EAH50_RS22710	COG2188	Transcriptional regulator
EAH50_RS22715	COG3624	Phosphonate C-P lyase system protein PhnG
EAH50_RS22720	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EAH50_RS22725	COG3626	phosphonate metabolism
EAH50_RS22730	COG3627	carbon phosphorus lyase activity
EAH50_RS22735	COG4107	phosphonate C-P lyase system protein PhnK
EAH50_RS22740	COG4778	phosphonate C-P lyase system protein PhnL
EAH50_RS22745	COG3454	Phosphonate metabolism
EAH50_RS22750	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EAH50_RS22755	COG0456	acetyltransferase
EAH50_RS22760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EAH50_RS22770	COG0698	ribose 5-phosphate isomerase
EAH50_RS22775	COG1737	Transcriptional regulator
EAH50_RS22780	COG1879	ABC-type sugar transport system periplasmic component
EAH50_RS22785	COG1129	ABC transporter
EAH50_RS22790	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS22795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAH50_RS22800	COG1940	carbohydrate kinase activity
EAH50_RS22820	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EAH50_RS22830	COG1566	PFAM secretion protein HlyD family protein
EAH50_RS22850	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAH50_RS22855	COG1301	dicarboxylic acid transport
EAH50_RS22860	COG4235	cytochrome complex assembly
EAH50_RS22865	COG3088	subunit of a heme lyase
EAH50_RS22870	COG1138	Cytochrome C-type biogenesis protein
EAH50_RS22875	COG3301	Polysulphide reductase, NrfD
EAH50_RS22880	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS22885	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EAH50_RS22895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAH50_RS22900	COG3162	membrane
EAH50_RS22910	COG1357	PFAM Pentapeptide repeats (8 copies)
EAH50_RS22915	COG0025	NhaP-type Na H and K H
EAH50_RS22920	COG2252	PERMEase
EAH50_RS22925	COG0789	Transcriptional regulator
EAH50_RS22930	COG2207	Transcriptional regulator
EAH50_RS22935	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAH50_RS22945	COG0629	single-stranded DNA binding
EAH50_RS22950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAH50_RS22955	COG2315	Protein conserved in bacteria
EAH50_RS22960	COG0432	Pfam Uncharacterised protein family UPF0047
EAH50_RS22965	COG3700	Belongs to the class B bacterial acid phosphatase family
EAH50_RS22975	COG1448	Aminotransferase
EAH50_RS22980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAH50_RS22985	COG0305	Participates in initiation and elongation during chromosome replication
EAH50_RS22990	COG0604	alcohol dehydrogenase
EAH50_RS23000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAH50_RS23010	COG0735	belongs to the Fur family
EAH50_RS23015	COG3237	CsbD-like
EAH50_RS23020	COG0534	Mate efflux family protein
EAH50_RS23030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAH50_RS23065	COG3842	ATPase activity
EAH50_RS23070	COG2182	Extracellular solute-binding protein
EAH50_RS23075	COG1175	transmembrane transport
EAH50_RS23080	COG3833	ABC-type maltose transport systems, permease component
EAH50_RS23085	COG2814	Major facilitator Superfamily
EAH50_RS23085	COG0477	Major facilitator Superfamily
EAH50_RS23100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAH50_RS23130	COG0527	aspartate kinase activity
EAH50_RS23140	COG1187	pseudouridine synthase activity
EAH50_RS23150	COG1283	sodium-dependent phosphate transmembrane transporter activity
EAH50_RS23155	COG1410	methionine synthase
EAH50_RS23155	COG0646	methionine synthase
EAH50_RS23160	COG1414	Transcriptional regulator
EAH50_RS23175	COG2224	Isocitrate lyase
EAH50_RS23180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAH50_RS23190	COG0456	acetyltransferase
EAH50_RS23220	COG0151	Belongs to the GarS family
EAH50_RS23225	COG2204	response regulator
EAH50_RS23230	COG4191	Histidine kinase
EAH50_RS23235	COG3678	ATP-independent chaperone mediated protein folding
EAH50_RS23250	COG3068	Protein conserved in bacteria
EAH50_RS23285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EAH50_RS23290	COG2104	thiamine diphosphate biosynthetic process
EAH50_RS23300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EAH50_RS23340	COG0250	Participates in transcription elongation, termination and antitermination
EAH50_RS23345	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAH50_RS23380	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EAH50_RS23380	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EAH50_RS23385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EAH50_RS23410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EAH50_RS23415	COG4206	TonB-dependent receptor
EAH50_RS23430	COG1309	transcriptional regulator
EAH50_RS23440	COG0583	DNA-binding transcription factor activity
EAH50_RS23455	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EAH50_RS23475	COG2194	sulfuric ester hydrolase activity
EAH50_RS23480	COG2207	Transcriptional regulator
EAH50_RS23485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS23490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAH50_RS23495	COG1882	Formate acetyltransferase
EAH50_RS23500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS23505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS23510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAH50_RS23510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS23510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS23515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAH50_RS23520	COG0371	Dehydrogenase
EAH50_RS23525	COG3738	Protein conserved in bacteria
EAH50_RS23530	COG0697	spore germination
EAH50_RS23540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EAH50_RS23545	COG0527	aspartate kinase activity
EAH50_RS23545	COG0460	homoserine dehydrogenase
EAH50_RS23550	COG0626	cystathionine gamma-synthase activity
EAH50_RS23560	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EAH50_RS23570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAH50_RS23575	COG1609	Transcriptional regulator
EAH50_RS23580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAH50_RS23595	COG1575	Belongs to the MenA family. Type 1 subfamily
EAH50_RS23610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EAH50_RS23620	COG1494	fructose-1,6-bisphosphatase
EAH50_RS23630	COG0589	response to stress
EAH50_RS23635	COG3691	Protein conserved in bacteria
EAH50_RS23640	COG3152	Membrane
EAH50_RS23660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAH50_RS23675	COG3678	ATP-independent chaperone mediated protein folding
EAH50_RS23680	COG0745	RESPONSE REGULATOR receiver
EAH50_RS23685	COG2205	protein histidine kinase activity
EAH50_RS23690	COG2258	MOSC domain
EAH50_RS23700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EAH50_RS23745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS23750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS23750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAH50_RS23755	COG1363	Peptidase, m42
EAH50_RS23760	COG3711	transcriptional antiterminator
EAH50_RS23760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAH50_RS23775	COG3383	formate dehydrogenase (NAD+) activity
EAH50_RS23775	COG0243	molybdopterin cofactor binding
EAH50_RS23780	COG3383	formate dehydrogenase (NAD+) activity
EAH50_RS23780	COG0243	molybdopterin cofactor binding
EAH50_RS23785	COG0437	4 iron, 4 sulfur cluster binding
EAH50_RS23790	COG2864	formate dehydrogenase
EAH50_RS23800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAH50_RS23805	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAH50_RS23810	COG0456	acetyltransferase
EAH50_RS23825	COG1011	Hydrolase
EAH50_RS23830	COG1349	DNA-binding transcription factor activity
EAH50_RS23835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS23840	COG2084	Dehydrogenase
EAH50_RS23845	COG3684	Belongs to the aldolase LacD family
EAH50_RS23850	COG2942	2-epimerase
EAH50_RS23855	COG2017	converts alpha-aldose to the beta-anomer
EAH50_RS23865	COG1217	gtp-binding protein TYPA
EAH50_RS23870	COG0174	glutamine synthetase
EAH50_RS23875	COG3852	Histidine kinase
EAH50_RS23880	COG2204	response regulator
EAH50_RS23890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAH50_RS23895	COG3078	GTPase activator activity
EAH50_RS23905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAH50_RS23905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAH50_RS23915	COG0204	Acyl-transferase
EAH50_RS23920	COG5339	Protein conserved in bacteria
EAH50_RS23925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAH50_RS23930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAH50_RS23935	COG3084	Protein conserved in bacteria
EAH50_RS23940	COG0746	molybdenum cofactor guanylyltransferase activity
EAH50_RS23945	COG1763	Mo-molybdopterin cofactor biosynthetic process
EAH50_RS23975	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EAH50_RS23980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAH50_RS23985	COG1739	Uncharacterized protein family UPF0029
EAH50_RS24005	COG0543	2 iron, 2 sulfur cluster binding
EAH50_RS24015	COG0250	Participates in transcription elongation, termination and antitermination
EAH50_RS24025	COG0805	protein transport
EAH50_RS24035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAH50_RS24045	COG3165	ubiquinone biosynthetic process from chorismate
EAH50_RS24055	COG1322	Protein conserved in bacteria
EAH50_RS24060	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EAH50_RS24065	COG0412	Dienelactone hydrolase
EAH50_RS24075	COG0583	DNA-binding transcription factor activity
EAH50_RS24080	COG0697	spore germination
EAH50_RS24085	COG0561	phosphatase activity
EAH50_RS24090	COG2267	carboxylic ester hydrolase activity
EAH50_RS24095	COG1280	lysine exporter protein (LysE YggA)
EAH50_RS24100	COG1280	lysine exporter protein (LysE YggA)
EAH50_RS24105	COG0514	ATP-dependent DNA helicase (RecQ)
EAH50_RS24110	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EAH50_RS24115	COG2050	protein possibly involved in aromatic compounds catabolism
EAH50_RS24120	COG2962	Rard protein
EAH50_RS24140	COG0598	Magnesium transport protein CorA
EAH50_RS24145	COG3698	Phosphodiester glycosidase
EAH50_RS24150	COG0210	DNA helicase
EAH50_RS24155	COG1011	Hydrolase
EAH50_RS24165	COG3159	Protein conserved in bacteria
EAH50_RS24175	COG5567	small periplasmic lipoprotein
EAH50_RS24185	COG3072	Adenylate cyclase
EAH50_RS24195	COG1587	Uroporphyrinogen-III synthase
EAH50_RS24200	COG2959	enzyme of heme biosynthesis
EAH50_RS24205	COG3071	HemY protein
EAH50_RS24210	COG3119	arylsulfatase activity
EAH50_RS24215	COG0641	radical SAM
EAH50_RS24240	COG1113	amino acid transport
EAH50_RS24260	COG2244	polysaccharide biosynthetic process
EAH50_RS24265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EAH50_RS24270	COG0456	acetyltransferase
EAH50_RS24275	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EAH50_RS24280	COG1088	dTDP-glucose 4,6-dehydratase activity
EAH50_RS24285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EAH50_RS24290	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EAH50_RS24295	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EAH50_RS24300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EAH50_RS24310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EAH50_RS24320	COG3118	belongs to the thioredoxin family
EAH50_RS24335	COG0210	DNA helicase
EAH50_RS24345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAH50_RS24355	COG0583	DNA-binding transcription factor activity
EAH50_RS24360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAH50_RS24370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAH50_RS24375	COG3978	acetolactate synthase activity
EAH50_RS24395	COG0606	chelatase, subunit chli
EAH50_RS24400	COG3085	chromosome segregation
EAH50_RS24440	COG2186	Transcriptional regulator
EAH50_RS24445	COG0477	Major facilitator Superfamily
EAH50_RS24450	COG1609	Transcriptional regulator
EAH50_RS24455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAH50_RS24460	COG1879	ABC-type sugar transport system periplasmic component
EAH50_RS24465	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAH50_RS24470	COG1129	ABC transporter
EAH50_RS24500	COG1522	sequence-specific DNA binding
EAH50_RS24505	COG0716	FMN binding
EAH50_RS24520	COG3312	ion transport
EAH50_RS24570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EAH50_RS24575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAH50_RS24580	COG0573	inorganic phosphate transmembrane transporter activity
EAH50_RS24585	COG0581	inorganic phosphate transmembrane transporter activity
EAH50_RS24590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAH50_RS24595	COG0704	Plays a role in the regulation of phosphate uptake
EAH50_RS24610	COG2252	PERMEase
EAH50_RS24615	COG0431	NADPH-dependent FMN reductase
EAH50_RS24620	COG2091	lysine biosynthetic process via aminoadipic acid
EAH50_RS24635	COG0814	amino acid
EAH50_RS24695	COG3539	Fimbrial protein
EAH50_RS24700	COG3121	Chaperone
EAH50_RS24705	COG3188	usher protein
EAH50_RS24730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EAH50_RS24800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAH50_RS24960	COG3941	tape measure
EAH50_RS25005	COG4932	domain protein
EAH50_RS25005	COG5492	domain, Protein
EAH50_RS25055	COG1475	DNA binding
EAH50_RS25060	COG1475	DNA binding
EAH50_RS25160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAH50_RS25230	COG0328	RNA-DNA hybrid ribonuclease activity
EAH50_RS25250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAH50_RS25275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis