locus-tag	class	description
HP432_RS00120	COG3344	reverse transcriptase
HP432_RS00130	COG2271	Major facilitator Superfamily
HP432_RS00140	COG0246	Mannitol dehydrogenase
HP432_RS00150	COG2186	Transcriptional regulator
HP432_RS00190	COG3539	Fimbrial protein
HP432_RS00195	COG3121	Chaperone
HP432_RS00215	COG0697	spore germination
HP432_RS00310	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HP432_RS00315	COG3421	Type III restriction
HP432_RS00375	COG2026	Addiction module toxin, RelE StbE family
HP432_RS00410	COG1192	Involved in chromosome partitioning
HP432_RS00515	COG4221	oxidoreductase activity
HP432_RS00585	COG0739	heme binding
HP432_RS00615	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS00650	COG3706	GGDEF domain
HP432_RS00670	COG2826	transposase and inactivated derivatives, IS30 family
HP432_RS00690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HP432_RS00700	COG3436	PFAM IS66 Orf2 family protein
HP432_RS00760	COG2433	Pfam Transposase IS66
HP432_RS00765	COG3436	PFAM IS66 Orf2 family protein
HP432_RS00775	COG2194	sulfuric ester hydrolase activity
HP432_RS00780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HP432_RS00905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HP432_RS00945	COG3121	Chaperone
HP432_RS00950	COG3539	Fimbrial protein
HP432_RS00960	COG1585	Membrane protein implicated in regulation of membrane protease activity
HP432_RS00965	COG2268	Band 7 protein
HP432_RS00990	COG3025	triphosphatase activity
HP432_RS00995	COG4991	sh3 domain protein
HP432_RS01010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HP432_RS01020	COG0583	DNA-binding transcription factor activity
HP432_RS01025	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HP432_RS01030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HP432_RS01035	COG0471	metal ion transport
HP432_RS01045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HP432_RS01050	COG0358	DNA primase activity
HP432_RS01055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HP432_RS01070	COG2375	cellular response to nickel ion
HP432_RS01075	COG1695	Transcriptional regulator
HP432_RS01080	COG0840	transmembrane signaling receptor activity
HP432_RS01090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HP432_RS01095	COG1609	Transcriptional regulator
HP432_RS01100	COG3250	beta-galactosidase activity
HP432_RS01105	COG2731	YhcH YjgK YiaL family protein
HP432_RS01110	COG0531	amino acid
HP432_RS01120	COG3408	Glycogen debranching enzyme
HP432_RS01120	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HP432_RS01125	COG1902	pentaerythritol trinitrate reductase activity
HP432_RS01125	COG0446	pyridine nucleotide-disulphide oxidoreductase
HP432_RS01140	COG1451	nucleotide metabolic process
HP432_RS01145	COG2949	membrane
HP432_RS01150	COG0673	inositol 2-dehydrogenase activity
HP432_RS01155	COG0861	Integral membrane protein TerC family
HP432_RS01160	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HP432_RS01170	COG2721	sulfolactate sulfo-lyase activity
HP432_RS01180	COG2271	Major facilitator Superfamily
HP432_RS01185	COG2186	Transcriptional regulator
HP432_RS01190	COG0586	Pfam SNARE associated Golgi protein
HP432_RS01200	COG1422	Protein of unknown function (DUF1090)
HP432_RS01205	COG4575	ribosome binding
HP432_RS01210	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HP432_RS01220	COG2259	Doxx family
HP432_RS01225	COG0435	Glutathione S-transferase
HP432_RS01230	COG3152	Membrane
HP432_RS01235	COG3152	Membrane
HP432_RS01240	COG0583	DNA-binding transcription factor activity
HP432_RS01245	COG1741	Belongs to the pirin family
HP432_RS01260	COG0814	amino acid
HP432_RS01265	COG1760	l-serine dehydratase
HP432_RS01270	COG0251	oxidation-reduction process
HP432_RS01275	COG1882	Formate acetyltransferase
HP432_RS01280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HP432_RS01290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HP432_RS01295	COG0583	DNA-binding transcription factor activity
HP432_RS01320	COG1929	Belongs to the glycerate kinase type-1 family
HP432_RS01325	COG2084	Dehydrogenase
HP432_RS01335	COG2271	Major facilitator Superfamily
HP432_RS01340	COG2721	sulfolactate sulfo-lyase activity
HP432_RS01345	COG2002	toxin-antitoxin pair type II binding
HP432_RS01365	COG1349	DNA-binding transcription factor activity
HP432_RS01375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS01385	COG3716	PTS system mannose fructose sorbose family IID component
HP432_RS01390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS01400	COG2222	sugar isomerase
HP432_RS01410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS01415	COG3715	PTS system
HP432_RS01420	COG3716	PTS system mannose fructose sorbose family IID component
HP432_RS01425	COG0363	glucosamine-6-phosphate deaminase activity
HP432_RS01430	COG3539	Fimbrial protein
HP432_RS01435	COG3121	Chaperone
HP432_RS01440	COG3188	usher protein
HP432_RS01445	COG3539	Fimbrial protein
HP432_RS01450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HP432_RS01455	COG3107	peptidoglycan biosynthetic process
HP432_RS01470	COG2823	Periplasmic or secreted lipoprotein
HP432_RS01475	COG0701	Predicted permease
HP432_RS01480	COG0702	epimerase
HP432_RS01485	COG0693	protein deglycase activity
HP432_RS01500	COG3153	acetyltransferase
HP432_RS01505	COG3154	lipid carrier protein
HP432_RS01510	COG0826	peptidase U32
HP432_RS01515	COG0826	peptidase U32
HP432_RS01520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HP432_RS01525	COG0814	amino acid
HP432_RS01530	COG0513	Belongs to the DEAD box helicase family
HP432_RS01570	COG0195	Participates in both transcription termination and antitermination
HP432_RS01590	COG2194	sulfuric ester hydrolase activity
HP432_RS01600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HP432_RS01610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HP432_RS01615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HP432_RS01625	COG1534	Rna-binding protein
HP432_RS01630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HP432_RS01635	COG2027	D-alanyl-D-alanine carboxypeptidase
HP432_RS01645	COG0697	spore germination
HP432_RS01660	COG0142	geranyltranstransferase activity
HP432_RS01665	COG3423	Transcriptional regulator
HP432_RS01675	COG5007	Belongs to the BolA IbaG family
HP432_RS01680	COG3113	response to antibiotic
HP432_RS01685	COG2854	intermembrane phospholipid transfer
HP432_RS01690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HP432_RS01695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HP432_RS01700	COG1127	ABC transporter
HP432_RS01705	COG0530	calcium, potassium:sodium antiporter activity
HP432_RS01710	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HP432_RS01710	COG0517	IMP dehydrogenase activity
HP432_RS01715	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HP432_RS01720	COG3117	lipopolysaccharide transmembrane transporter activity
HP432_RS01725	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HP432_RS01730	COG1137	ATPase activity
HP432_RS01735	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HP432_RS01740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HP432_RS01755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS01760	COG0515	serine threonine protein kinase
HP432_RS01770	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HP432_RS01775	COG0784	Response regulator, receiver
HP432_RS01775	COG5002	protein histidine kinase activity
HP432_RS01775	COG2198	Histidine kinase
HP432_RS01780	COG1242	4 iron, 4 sulfur cluster binding
HP432_RS01785	COG0069	glutamate synthase activity
HP432_RS01785	COG0067	glutamate synthase
HP432_RS01785	COG0070	glutamate synthase
HP432_RS01790	COG0493	'glutamate synthase
HP432_RS01795	COG3539	Fimbrial protein
HP432_RS01800	COG3121	Chaperone
HP432_RS01805	COG3188	usher protein
HP432_RS01815	COG3539	Fimbrial protein
HP432_RS01830	COG4804	nuclease activity
HP432_RS01835	COG2731	YhcH YjgK YiaL family protein
HP432_RS01865	COG3069	C4-dicarboxylate transmembrane transporter activity
HP432_RS01870	COG2969	positive regulation of protein catabolic process
HP432_RS01875	COG0625	glutathione transferase activity
HP432_RS01890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HP432_RS01895	COG3105	Protein conserved in bacteria
HP432_RS01900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HP432_RS01905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HP432_RS01925	COG2732	(Barnase) inhibitor
HP432_RS01945	COG0583	DNA-binding transcription factor activity
HP432_RS01950	COG0312	modulator of DNA gyrase
HP432_RS01955	COG3164	Protein of unknown function
HP432_RS01960	COG1530	ribonuclease E activity
HP432_RS01970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HP432_RS01975	COG1792	Involved in formation and maintenance of cell shape
HP432_RS01980	COG1077	Cell shape determining protein MreB Mrl
HP432_RS01985	COG2199	diguanylate cyclase activity
HP432_RS01985	COG2200	EAL domain
HP432_RS01990	COG0604	alcohol dehydrogenase
HP432_RS01995	COG0511	ligase activity, forming carbon-carbon bonds
HP432_RS02000	COG0439	Biotin carboxylase
HP432_RS02005	COG3924	membrane
HP432_RS02010	COG4145	pantothenate transmembrane transporter activity
HP432_RS02020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HP432_RS02030	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HP432_RS02040	COG1309	transcriptional regulator
HP432_RS02045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS02050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HP432_RS02060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS02065	COG4597	amino acid ABC transporter
HP432_RS02070	COG0765	amino acid transport
HP432_RS02075	COG1126	abc transporter atp-binding protein
HP432_RS02110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HP432_RS02130	COG0551	DNA topoisomerase type I activity
HP432_RS02140	COG0758	DNA mediated transformation
HP432_RS02160	COG0569	domain protein
HP432_RS02170	COG3036	rescue of stalled ribosome
HP432_RS02175	COG0789	Transcriptional regulator
HP432_RS02215	COG0201	protein transport
HP432_RS02305	COG0089	rRNA binding
HP432_RS02330	COG3267	Type II secretory pathway component ExeA
HP432_RS02330	COG3409	Peptidoglycan-binding domain 1 protein
HP432_RS02335	COG3031	protein transport across the cell outer membrane
HP432_RS02340	COG1450	Type ii and iii secretion system protein
HP432_RS02345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HP432_RS02350	COG1459	type II secretion system
HP432_RS02355	COG2165	general secretion pathway protein
HP432_RS02360	COG2165	general secretion pathway protein
HP432_RS02365	COG2165	general secretion pathway protein
HP432_RS02370	COG4795	General secretion pathway protein
HP432_RS02375	COG3156	type II secretion system protein K
HP432_RS02380	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HP432_RS02385	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HP432_RS02390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HP432_RS02395	COG2193	ferroxidase activity
HP432_RS02400	COG2906	2 iron, 2 sulfur cluster binding
HP432_RS02405	COG3979	chitinase
HP432_RS02445	COG2964	Protein conserved in bacteria
HP432_RS02450	COG0545	Peptidyl-prolyl cis-trans isomerase
HP432_RS02460	COG1047	Peptidyl-prolyl cis-trans
HP432_RS02465	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HP432_RS02480	COG0488	(ABC) transporter
HP432_RS02485	COG0429	hydrolase of the alpha beta-hydrolase fold
HP432_RS02495	COG3954	Phosphoribulokinase
HP432_RS02500	COG1765	OsmC-like protein
HP432_RS02505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HP432_RS02510	COG1289	transmembrane transporter activity
HP432_RS02515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HP432_RS02520	COG0512	Glutamine amidotransferase of anthranilate synthase
HP432_RS02525	COG2184	nucleotidyltransferase activity
HP432_RS02535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HP432_RS02545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HP432_RS02550	COG2146	nitrite reductase [NAD(P)H] activity
HP432_RS02555	COG2116	formate transmembrane transporter activity
HP432_RS02570	COG0531	amino acid
HP432_RS02575	COG2222	sugar isomerase
HP432_RS02580	COG1082	Xylose isomerase domain protein TIM barrel
HP432_RS02585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HP432_RS02590	COG2188	Transcriptional regulator
HP432_RS02595	COG0626	cystathionine gamma-synthase activity
HP432_RS02610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HP432_RS02615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HP432_RS02620	COG3457	Alanine racemase
HP432_RS02630	COG2188	Transcriptional regulator
HP432_RS02635	COG0180	Tryptophanyl-tRNA synthetase
HP432_RS02640	COG0546	phosphoglycolate phosphatase activity
HP432_RS02645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HP432_RS02650	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HP432_RS02655	COG3266	domain, Protein
HP432_RS02670	COG4796	Type ii and iii secretion system protein
HP432_RS02685	COG3166	PFAM Fimbrial assembly family protein
HP432_RS02690	COG4972	Pilus assembly protein
HP432_RS02695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HP432_RS02700	COG0494	nUDIX hydrolase
HP432_RS02710	COG1011	Hydrolase
HP432_RS02715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HP432_RS02725	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HP432_RS02735	COG2205	protein histidine kinase activity
HP432_RS02740	COG0745	RESPONSE REGULATOR receiver
HP432_RS02745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HP432_RS02750	COG2183	response to ionizing radiation
HP432_RS02755	COG1918	ferrous iron import across plasma membrane
HP432_RS02760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HP432_RS02770	COG5464	transposase or invertase
HP432_RS02785	COG1040	competence protein
HP432_RS02795	COG2610	gluconate transmembrane transporter activity
HP432_RS02800	COG1640	4-alpha-glucanotransferase
HP432_RS02805	COG0058	SHG alpha-glucan phosphorylase activity
HP432_RS02820	COG1690	Belongs to the RtcB family
HP432_RS02825	COG4650	regulator
HP432_RS02830	COG1349	DNA-binding transcription factor activity
HP432_RS02845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HP432_RS02865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HP432_RS02870	COG0058	SHG alpha-glucan phosphorylase activity
HP432_RS02895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HP432_RS02900	COG2095	MarC family integral membrane protein
HP432_RS02905	COG2610	gluconate transmembrane transporter activity
HP432_RS02910	COG3265	gluconokinase activity
HP432_RS02915	COG1609	Transcriptional regulator
HP432_RS02920	COG1741	Belongs to the pirin family
HP432_RS02925	COG0673	inositol 2-dehydrogenase activity
HP432_RS02930	COG1247	-acetyltransferase
HP432_RS02935	COG3157	Type VI secretion system effector, Hcp
HP432_RS02955	COG0405	Gamma-glutamyltransferase
HP432_RS02965	COG0584	glycerophosphoryl diester phosphodiesterase
HP432_RS02970	COG3842	ATPase activity
HP432_RS02975	COG0395	ABC-type sugar transport system, permease component
HP432_RS02980	COG1175	transmembrane transport
HP432_RS02985	COG1653	transport
HP432_RS02990	COG0410	ABC transporter
HP432_RS02995	COG0411	ABC transporter
HP432_RS03000	COG4177	L-phenylalanine transmembrane transporter activity
HP432_RS03005	COG0559	Belongs to the binding-protein-dependent transport system permease family
HP432_RS03010	COG0683	leucine binding
HP432_RS03015	COG0456	acetyltransferase
HP432_RS03020	COG0683	leucine binding
HP432_RS03025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HP432_RS03030	COG2177	Part of the ABC transporter FtsEX involved in
HP432_RS03035	COG2884	Cell division ATP-binding protein ftsE
HP432_RS03040	COG0552	protein localization to endoplasmic reticulum
HP432_RS03045	COG0742	ribosomal rna small subunit methyltransferase
HP432_RS03050	COG3776	membrane
HP432_RS03060	COG3714	YhhN family
HP432_RS03075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HP432_RS03085	COG0477	Major facilitator Superfamily
HP432_RS03090	COG0628	permease
HP432_RS03095	COG2091	lysine biosynthetic process via aminoadipic acid
HP432_RS03100	COG0747	negative chemotaxis
HP432_RS03105	COG0601	transmembrane transport
HP432_RS03110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HP432_RS03115	COG0444	Belongs to the ABC transporter superfamily
HP432_RS03120	COG1124	(ABC) transporter
HP432_RS03130	COG3209	COG3209 Rhs family protein
HP432_RS03140	COG1413	lyase activity
HP432_RS03145	COG5433	transposase activity
HP432_RS03150	COG0842	Transport permease protein
HP432_RS03155	COG0842	Transport permease protein
HP432_RS03155	COG1129	ABC transporter
HP432_RS03160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS03180	COG2081	HI0933 family
HP432_RS03185	COG0306	phosphate transporter
HP432_RS03195	COG0589	response to stress
HP432_RS03200	COG3104	oligopeptide transport
HP432_RS03210	COG0339	signal peptide processing
HP432_RS03215	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HP432_RS03220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HP432_RS03230	COG0640	Transcriptional regulator
HP432_RS03235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HP432_RS03240	COG1393	Belongs to the ArsC family
HP432_RS03250	COG3065	identical protein binding
HP432_RS03255	COG2197	response regulator
HP432_RS03260	COG1285	pathogenesis
HP432_RS03275	COG3247	response to pH
HP432_RS03280	COG2771	luxR family
HP432_RS03290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS03295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HP432_RS03300	COG2207	Transcriptional regulator
HP432_RS03305	COG2207	Transcriptional regulator
HP432_RS03310	COG0076	glutamate decarboxylase activity
HP432_RS03315	COG1858	cytochrome C peroxidase
HP432_RS03325	COG2197	response regulator
HP432_RS03330	COG0583	DNA-binding transcription factor activity
HP432_RS03335	COG1295	ribonuclease BN
HP432_RS03340	COG0477	Major facilitator Superfamily
HP432_RS03345	COG2982	Protein involved in outer membrane biogenesis
HP432_RS03350	COG2200	EAL domain
HP432_RS03360	COG0612	Peptidase, M16
HP432_RS03370	COG2199	diguanylate cyclase activity
HP432_RS03370	COG2200	EAL domain
HP432_RS03385	COG2194	sulfuric ester hydrolase activity
HP432_RS03395	COG0814	amino acid
HP432_RS03400	COG4608	Belongs to the ABC transporter superfamily
HP432_RS03405	COG0444	Belongs to the ABC transporter superfamily
HP432_RS03410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HP432_RS03415	COG0601	transmembrane transport
HP432_RS03420	COG0747	negative chemotaxis
HP432_RS03430	COG2194	sulfuric ester hydrolase activity
HP432_RS03435	COG2223	nitrite transmembrane transporter activity
HP432_RS03440	COG5571	outer membrane autotransporter
HP432_RS03445	COG2818	Glycosylase
HP432_RS03450	COG0456	acetyltransferase
HP432_RS03455	COG0243	molybdopterin cofactor binding
HP432_RS03460	COG2885	chlorophyll binding
HP432_RS03475	COG2944	sequence-specific DNA binding
HP432_RS03480	COG1278	Cold shock
HP432_RS03510	COG3274	enterobacterial common antigen metabolic process
HP432_RS03515	COG4682	membrane
HP432_RS03525	COG4682	membrane
HP432_RS03530	COG1070	Carbohydrate kinase
HP432_RS03540	COG4213	ABC transporter substrate-binding protein
HP432_RS03545	COG1129	ABC transporter
HP432_RS03550	COG4214	carbohydrate transport
HP432_RS03555	COG1609	Transcriptional regulator
HP432_RS03555	COG2207	Transcriptional regulator
HP432_RS03560	COG2992	FlgJ-related protein
HP432_RS03565	COG0366	Alpha amylase catalytic
HP432_RS03570	COG3977	Valine--pyruvate aminotransferase
HP432_RS03575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS03580	COG1414	Transcriptional regulator
HP432_RS03590	COG2731	YhcH YjgK YiaL family protein
HP432_RS03595	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HP432_RS03600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HP432_RS03605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HP432_RS03610	COG1070	Carbohydrate kinase
HP432_RS03615	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HP432_RS03620	COG3623	hexulose-6-phosphate isomerase
HP432_RS03625	COG0235	Class ii aldolase
HP432_RS03630	COG3713	MltA-interacting MipA family protein
HP432_RS03635	COG0583	DNA-binding transcription factor activity
HP432_RS03640	COG1566	PFAM secretion protein HlyD family protein
HP432_RS03655	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS03660	COG1454	alcohol dehydrogenase
HP432_RS03665	COG3276	selenocysteine insertion sequence binding
HP432_RS03675	COG0625	glutathione transferase activity
HP432_RS03690	COG1566	PFAM secretion protein HlyD family protein
HP432_RS03700	COG2213	PTS system mannitol-specific
HP432_RS03700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS03710	COG3722	fumarate hydratase activity
HP432_RS03725	COG1620	l-lactate permease
HP432_RS03730	COG2186	Transcriptional regulator
HP432_RS03740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HP432_RS03745	COG1045	serine acetyltransferase
HP432_RS03760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HP432_RS03765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HP432_RS03770	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HP432_RS03775	COG4942	peptidase
HP432_RS03780	COG2861	carbohydrate metabolic process
HP432_RS03785	COG1216	Glycosyl transferase, family 2
HP432_RS03795	COG0156	8-amino-7-oxononanoate synthase activity
HP432_RS03815	COG0859	PFAM glycosyl transferase family 9
HP432_RS03820	COG0859	PFAM glycosyl transferase family 9
HP432_RS03840	COG3642	lipopolysaccharide core region biosynthetic process
HP432_RS03850	COG0515	serine threonine protein kinase
HP432_RS03855	COG0438	transferase activity, transferring glycosyl groups
HP432_RS03860	COG0859	PFAM glycosyl transferase family 9
HP432_RS03865	COG1519	Transferase
HP432_RS03895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HP432_RS03920	COG1561	YicC-like family, N-terminal region
HP432_RS03960	COG2314	TM2 domain
HP432_RS03980	COG3645	SOS response
HP432_RS03985	COG2860	membrane
HP432_RS03995	COG0194	GDP metabolic process
HP432_RS04005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HP432_RS04010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HP432_RS04015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HP432_RS04020	COG0786	glutamate:sodium symporter activity
HP432_RS04025	COG2233	PERMEase
HP432_RS04030	COG2982	Protein involved in outer membrane biogenesis
HP432_RS04035	COG1501	Belongs to the glycosyl hydrolase 31 family
HP432_RS04045	COG2211	Major facilitator Superfamily
HP432_RS04060	COG2814	Major facilitator Superfamily
HP432_RS04065	COG0697	spore germination
HP432_RS04070	COG1464	Belongs to the NlpA lipoprotein family
HP432_RS04090	COG2252	PERMEase
HP432_RS04100	COG2271	Major facilitator Superfamily
HP432_RS04105	COG2271	Major facilitator Superfamily
HP432_RS04110	COG3851	Histidine kinase
HP432_RS04115	COG2197	response regulator
HP432_RS04120	COG0440	acetolactate synthase activity
HP432_RS04125	COG0028	Belongs to the TPP enzyme family
HP432_RS04140	COG2814	Major facilitator Superfamily
HP432_RS04145	COG0641	radical SAM
HP432_RS04155	COG2149	membrane
HP432_RS04165	COG3119	arylsulfatase activity
HP432_RS04170	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HP432_RS04175	COG2207	Transcriptional regulator
HP432_RS04190	COG2188	Transcriptional regulator
HP432_RS04210	COG5645	(Lipo)protein
HP432_RS04215	COG0823	Involved in the tonB-independent uptake of proteins
HP432_RS04225	COG2271	Major facilitator Superfamily
HP432_RS04235	COG0800	Aldolase
HP432_RS04240	COG3734	2-keto-3-deoxy-galactonokinase
HP432_RS04245	COG2186	Transcriptional regulator
HP432_RS04255	COG0561	phosphatase activity
HP432_RS04265	COG0187	DNA topoisomerase II activity
HP432_RS04275	COG0592	DNA-directed DNA polymerase activity
HP432_RS04325	COG0814	amino acid
HP432_RS04340	COG2091	lysine biosynthetic process via aminoadipic acid
HP432_RS04345	COG0431	NADPH-dependent FMN reductase
HP432_RS04350	COG2252	PERMEase
HP432_RS04355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HP432_RS04370	COG3196	Protein conserved in bacteria
HP432_RS04375	COG0363	glucosamine-6-phosphate deaminase activity
HP432_RS04380	COG2382	esterase
HP432_RS04390	COG2723	6-phospho-beta-galactosidase activity
HP432_RS04395	COG1263	PTS System
HP432_RS04395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS04395	COG2190	(PTS) system
HP432_RS04400	COG2826	transposase and inactivated derivatives, IS30 family
HP432_RS04415	COG2826	transposase and inactivated derivatives, IS30 family
HP432_RS04420	COG0704	Plays a role in the regulation of phosphate uptake
HP432_RS04425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HP432_RS04430	COG0581	inorganic phosphate transmembrane transporter activity
HP432_RS04435	COG0573	inorganic phosphate transmembrane transporter activity
HP432_RS04440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HP432_RS04445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HP432_RS04495	COG3312	ion transport
HP432_RS04510	COG0716	FMN binding
HP432_RS04515	COG1522	sequence-specific DNA binding
HP432_RS04545	COG1129	ABC transporter
HP432_RS04550	COG1172	Belongs to the binding-protein-dependent transport system permease family
HP432_RS04555	COG1879	ABC-type sugar transport system periplasmic component
HP432_RS04560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HP432_RS04565	COG1609	Transcriptional regulator
HP432_RS04570	COG0477	Major facilitator Superfamily
HP432_RS04575	COG2186	Transcriptional regulator
HP432_RS04615	COG3085	chromosome segregation
HP432_RS04620	COG0606	chelatase, subunit chli
HP432_RS04640	COG3978	acetolactate synthase activity
HP432_RS04645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HP432_RS04655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HP432_RS04660	COG0583	DNA-binding transcription factor activity
HP432_RS04670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HP432_RS04680	COG0210	DNA helicase
HP432_RS04695	COG3118	belongs to the thioredoxin family
HP432_RS04705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HP432_RS04710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HP432_RS04715	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HP432_RS04720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HP432_RS04725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HP432_RS04730	COG1088	dTDP-glucose 4,6-dehydratase activity
HP432_RS04735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HP432_RS04740	COG0456	acetyltransferase
HP432_RS04745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HP432_RS04750	COG2244	polysaccharide biosynthetic process
HP432_RS04770	COG1113	amino acid transport
HP432_RS04795	COG0641	radical SAM
HP432_RS04800	COG3119	arylsulfatase activity
HP432_RS04805	COG3071	HemY protein
HP432_RS04810	COG2959	enzyme of heme biosynthesis
HP432_RS04815	COG1587	Uroporphyrinogen-III synthase
HP432_RS04825	COG3072	Adenylate cyclase
HP432_RS04865	COG5567	small periplasmic lipoprotein
HP432_RS04875	COG3159	Protein conserved in bacteria
HP432_RS04885	COG1011	Hydrolase
HP432_RS04890	COG0210	DNA helicase
HP432_RS04895	COG3698	Phosphodiester glycosidase
HP432_RS04900	COG0598	Magnesium transport protein CorA
HP432_RS04915	COG2962	Rard protein
HP432_RS04920	COG2050	protein possibly involved in aromatic compounds catabolism
HP432_RS04925	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HP432_RS04930	COG0514	ATP-dependent DNA helicase (RecQ)
HP432_RS04935	COG1280	lysine exporter protein (LysE YggA)
HP432_RS04940	COG1280	lysine exporter protein (LysE YggA)
HP432_RS04945	COG2267	carboxylic ester hydrolase activity
HP432_RS04950	COG0561	phosphatase activity
HP432_RS04955	COG0697	spore germination
HP432_RS04960	COG0583	DNA-binding transcription factor activity
HP432_RS04970	COG0412	Dienelactone hydrolase
HP432_RS04975	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HP432_RS04980	COG1322	Protein conserved in bacteria
HP432_RS04990	COG3165	ubiquinone biosynthetic process from chorismate
HP432_RS05000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HP432_RS05005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HP432_RS05010	COG0805	protein transport
HP432_RS05015	COG0084	hydrolase, TatD family'
HP432_RS05020	COG0250	Participates in transcription elongation, termination and antitermination
HP432_RS05025	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HP432_RS05030	COG0543	2 iron, 2 sulfur cluster binding
HP432_RS05035	COG0183	Belongs to the thiolase family
HP432_RS05050	COG1739	Uncharacterized protein family UPF0029
HP432_RS05055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HP432_RS05060	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HP432_RS05090	COG1763	Mo-molybdopterin cofactor biosynthetic process
HP432_RS05095	COG0746	molybdenum cofactor guanylyltransferase activity
HP432_RS05100	COG3084	Protein conserved in bacteria
HP432_RS05105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HP432_RS05110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HP432_RS05115	COG5339	Protein conserved in bacteria
HP432_RS05120	COG0204	Acyl-transferase
HP432_RS05125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HP432_RS05125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HP432_RS05140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HP432_RS05150	COG2204	response regulator
HP432_RS05155	COG3852	Histidine kinase
HP432_RS05160	COG0174	glutamine synthetase
HP432_RS05170	COG2188	Transcriptional regulator
HP432_RS05175	COG1082	Xylose isomerase domain protein TIM barrel
HP432_RS05185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HP432_RS05190	COG2211	Major facilitator Superfamily
HP432_RS05195	COG2211	Major facilitator Superfamily
HP432_RS05200	COG1501	Belongs to the glycosyl hydrolase 31 family
HP432_RS05205	COG2017	converts alpha-aldose to the beta-anomer
HP432_RS05210	COG2942	2-epimerase
HP432_RS05215	COG3684	Belongs to the aldolase LacD family
HP432_RS05220	COG2084	Dehydrogenase
HP432_RS05225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HP432_RS05230	COG1349	DNA-binding transcription factor activity
HP432_RS05235	COG1011	Hydrolase
HP432_RS05250	COG0456	acetyltransferase
HP432_RS05255	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HP432_RS05260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HP432_RS05270	COG2864	formate dehydrogenase
HP432_RS05275	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS05295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS05295	COG3711	transcriptional antiterminator
HP432_RS05300	COG1363	Peptidase, m42
HP432_RS05305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS05305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS05310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS05350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HP432_RS05360	COG2258	MOSC domain
HP432_RS05365	COG2205	protein histidine kinase activity
HP432_RS05370	COG0745	RESPONSE REGULATOR receiver
HP432_RS05375	COG3678	ATP-independent chaperone mediated protein folding
HP432_RS05390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HP432_RS05410	COG3152	Membrane
HP432_RS05415	COG3691	Protein conserved in bacteria
HP432_RS05420	COG0589	response to stress
HP432_RS05425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HP432_RS05430	COG1494	fructose-1,6-bisphosphatase
HP432_RS05440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HP432_RS05455	COG1575	Belongs to the MenA family. Type 1 subfamily
HP432_RS05470	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HP432_RS05475	COG1609	Transcriptional regulator
HP432_RS05480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HP432_RS05490	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HP432_RS05500	COG0626	cystathionine gamma-synthase activity
HP432_RS05505	COG0527	aspartate kinase activity
HP432_RS05505	COG0460	homoserine dehydrogenase
HP432_RS05510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HP432_RS05520	COG0697	spore germination
HP432_RS05525	COG3738	Protein conserved in bacteria
HP432_RS05530	COG0371	Dehydrogenase
HP432_RS05535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HP432_RS05540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HP432_RS05540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS05540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS05545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS05550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS05555	COG1882	Formate acetyltransferase
HP432_RS05560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HP432_RS05565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS05570	COG2207	Transcriptional regulator
HP432_RS05575	COG2194	sulfuric ester hydrolase activity
HP432_RS05590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HP432_RS05605	COG0583	DNA-binding transcription factor activity
HP432_RS05615	COG1309	transcriptional regulator
HP432_RS05630	COG4206	TonB-dependent receptor
HP432_RS05635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HP432_RS05660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HP432_RS05665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HP432_RS05665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HP432_RS05700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HP432_RS05705	COG0250	Participates in transcription elongation, termination and antitermination
HP432_RS05745	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HP432_RS05755	COG2104	thiamine diphosphate biosynthetic process
HP432_RS05760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HP432_RS05795	COG3068	Protein conserved in bacteria
HP432_RS05810	COG3678	ATP-independent chaperone mediated protein folding
HP432_RS05815	COG4191	Histidine kinase
HP432_RS05820	COG2204	response regulator
HP432_RS05825	COG0151	Belongs to the GarS family
HP432_RS05855	COG0456	acetyltransferase
HP432_RS05865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HP432_RS05870	COG2224	Isocitrate lyase
HP432_RS05885	COG1414	Transcriptional regulator
HP432_RS05890	COG0646	methionine synthase
HP432_RS05890	COG1410	methionine synthase
HP432_RS05895	COG1283	sodium-dependent phosphate transmembrane transporter activity
HP432_RS05940	COG1187	pseudouridine synthase activity
HP432_RS05950	COG0527	aspartate kinase activity
HP432_RS05975	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HP432_RS05995	COG0477	Major facilitator Superfamily
HP432_RS05995	COG2814	Major facilitator Superfamily
HP432_RS06000	COG3833	ABC-type maltose transport systems, permease component
HP432_RS06005	COG1175	transmembrane transport
HP432_RS06010	COG2182	Extracellular solute-binding protein
HP432_RS06015	COG3842	ATPase activity
HP432_RS06050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HP432_RS06060	COG0534	Mate efflux family protein
HP432_RS06065	COG3237	CsbD-like
HP432_RS06070	COG0735	belongs to the Fur family
HP432_RS06080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HP432_RS06090	COG0604	alcohol dehydrogenase
HP432_RS06095	COG0305	Participates in initiation and elongation during chromosome replication
HP432_RS06100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HP432_RS06105	COG1448	Aminotransferase
HP432_RS06130	COG0432	Pfam Uncharacterised protein family UPF0047
HP432_RS06135	COG2315	Protein conserved in bacteria
HP432_RS06140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HP432_RS06145	COG0629	single-stranded DNA binding
HP432_RS06155	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HP432_RS06160	COG2207	Transcriptional regulator
HP432_RS06165	COG0789	Transcriptional regulator
HP432_RS06170	COG2252	PERMEase
HP432_RS06175	COG0025	NhaP-type Na H and K H
HP432_RS06200	COG3162	membrane
HP432_RS06205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HP432_RS06215	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HP432_RS06220	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS06225	COG3301	Polysulphide reductase, NrfD
HP432_RS06230	COG1138	Cytochrome C-type biogenesis protein
HP432_RS06235	COG3088	subunit of a heme lyase
HP432_RS06240	COG4235	cytochrome complex assembly
HP432_RS06245	COG1301	dicarboxylic acid transport
HP432_RS06250	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HP432_RS06260	COG1538	Outer membrane efflux protein
HP432_RS06265	COG1289	transmembrane transporter activity
HP432_RS06270	COG1566	PFAM secretion protein HlyD family protein
HP432_RS06280	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HP432_RS06285	COG1940	carbohydrate kinase activity
HP432_RS06290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HP432_RS06295	COG1172	Belongs to the binding-protein-dependent transport system permease family
HP432_RS06300	COG1129	ABC transporter
HP432_RS06305	COG1879	ABC-type sugar transport system periplasmic component
HP432_RS06310	COG1737	Transcriptional regulator
HP432_RS06315	COG0698	ribose 5-phosphate isomerase
HP432_RS06325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HP432_RS06330	COG0456	acetyltransferase
HP432_RS06335	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HP432_RS06340	COG3454	Phosphonate metabolism
HP432_RS06345	COG4778	phosphonate C-P lyase system protein PhnL
HP432_RS06350	COG4107	phosphonate C-P lyase system protein PhnK
HP432_RS06355	COG3627	carbon phosphorus lyase activity
HP432_RS06360	COG3626	phosphonate metabolism
HP432_RS06365	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HP432_RS06370	COG3624	Phosphonate C-P lyase system protein PhnG
HP432_RS06375	COG2188	Transcriptional regulator
HP432_RS06380	COG3639	organic phosphonate transmembrane transporter activity
HP432_RS06385	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HP432_RS06390	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HP432_RS06395	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HP432_RS06400	COG2824	Alkylphosphonate utilization operon protein PhnA
HP432_RS06415	COG0477	Major facilitator Superfamily
HP432_RS06425	COG0642	Histidine kinase
HP432_RS06430	COG0745	RESPONSE REGULATOR receiver
HP432_RS06435	COG2194	sulfuric ester hydrolase activity
HP432_RS06440	COG0531	amino acid
HP432_RS06445	COG2207	Transcriptional regulator
HP432_RS06450	COG1982	Orn Lys Arg decarboxylase major
HP432_RS06455	COG2169	Transcriptional regulator
HP432_RS06460	COG1486	melibiose metabolic process
HP432_RS06465	COG2211	Major facilitator Superfamily
HP432_RS06470	COG3647	Membrane
HP432_RS06475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HP432_RS06475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HP432_RS06480	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HP432_RS06485	COG4565	transcriptional regulatory protein
HP432_RS06490	COG3290	protein histidine kinase activity
HP432_RS06495	COG3592	Divergent 4Fe-4S mono-cluster
HP432_RS06500	COG2388	GCN5-related N-acetyl-transferase
HP432_RS06515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HP432_RS06520	COG3104	oligopeptide transport
HP432_RS06525	COG1982	Orn Lys Arg decarboxylase major
HP432_RS06530	COG0531	amino acid
HP432_RS06535	COG3710	Transcriptional regulator
HP432_RS06545	COG1309	transcriptional regulator
HP432_RS06550	COG4232	protein-disulfide reductase activity
HP432_RS06560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HP432_RS06565	COG1027	Aspartate ammonia-lyase
HP432_RS06570	COG3030	protein affecting phage T7 exclusion by the F plasmid
HP432_RS06575	COG0531	amino acid
HP432_RS06600	COG1509	lysine 2,3-aminomutase activity
HP432_RS06610	COG5510	response to toxic substance
HP432_RS06615	COG5510	response to toxic substance
HP432_RS06620	COG2076	Multidrug Resistance protein
HP432_RS06625	COG3040	lipid binding
HP432_RS06630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HP432_RS06645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HP432_RS06650	COG1053	succinate dehydrogenase
HP432_RS06660	COG0531	amino acid
HP432_RS06675	COG3264	Mechanosensitive ion channel
HP432_RS06675	COG1511	domain protein
HP432_RS06715	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HP432_RS06720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HP432_RS06720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HP432_RS06725	COG0802	atpase or kinase
HP432_RS06730	COG0860	N-Acetylmuramoyl-L-alanine amidase
HP432_RS06750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HP432_RS06755	COG0330	HflC and HflK could
HP432_RS06760	COG0330	HflC and HflK could
HP432_RS06765	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HP432_RS06780	COG0557	exoribonuclease II activity
HP432_RS06785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HP432_RS06790	COG3789	protein conserved in bacteria
HP432_RS06795	COG1842	Phage shock protein A
HP432_RS06805	COG3766	membrane
HP432_RS06810	COG5463	Belongs to the UPF0441 family
HP432_RS06815	COG0754	glutathionylspermidine amidase activity
HP432_RS06820	COG1960	acyl-CoA dehydrogenase activity
HP432_RS06830	COG3650	response to hydrogen peroxide
HP432_RS06835	COG1073	alpha beta
HP432_RS06850	COG3037	sugar-specific permease SgaT UlaA
HP432_RS06855	COG3414	Phosphotransferase system galactitol-specific IIB component
HP432_RS06895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HP432_RS06905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HP432_RS06915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HP432_RS06920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HP432_RS06925	COG4670	ketone body catabolic process
HP432_RS06930	COG1024	Enoyl-CoA hydratase
HP432_RS06945	COG1309	transcriptional regulator
HP432_RS06950	COG3061	Opacity-associated protein A
HP432_RS06955	COG0545	Peptidyl-prolyl cis-trans isomerase
HP432_RS06960	COG1113	amino acid transport
HP432_RS06970	COG0697	spore germination
HP432_RS06975	COG0702	epimerase
HP432_RS06980	COG1733	regulation of RNA biosynthetic process
HP432_RS06985	COG0737	Belongs to the 5'-nucleotidase family
HP432_RS06990	COG1218	3'(2'),5'-bisphosphate nucleotidase
HP432_RS06995	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HP432_RS07005	COG1253	flavin adenine dinucleotide binding
HP432_RS07015	COG0729	surface antigen
HP432_RS07020	COG2911	Protein conserved in bacteria
HP432_RS07025	COG2105	PFAM AIG2 family protein
HP432_RS07030	COG2336	PFAM SpoVT AbrB
HP432_RS07035	COG2337	Toxic component of a toxin-antitoxin (TA) module
HP432_RS07040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HP432_RS07045	COG1879	ABC-type sugar transport system periplasmic component
HP432_RS07050	COG1129	ABC transporter
HP432_RS07055	COG1172	Belongs to the binding-protein-dependent transport system permease family
HP432_RS07060	COG1172	Belongs to the binding-protein-dependent transport system permease family
HP432_RS07070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HP432_RS07080	COG0312	modulator of DNA gyrase
HP432_RS07085	COG3783	Cytochrome b(562)
HP432_RS07090	COG0602	queuosine metabolic process
HP432_RS07095	COG1328	CTP reductase activity
HP432_RS07100	COG0366	Alpha amylase catalytic
HP432_RS07105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS07105	COG1263	PTS System
HP432_RS07110	COG1609	Transcriptional regulator
HP432_RS07120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HP432_RS07125	COG0251	oxidation-reduction process
HP432_RS07145	COG0251	oxidation-reduction process
HP432_RS07150	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS07155	COG1309	transcriptional regulator
HP432_RS07160	COG2731	YhcH YjgK YiaL family protein
HP432_RS07175	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HP432_RS07180	COG0456	acetyltransferase
HP432_RS07185	COG4269	membrane
HP432_RS07190	COG0525	valine-tRNA ligase activity
HP432_RS07195	COG2927	DNA polymerase III (CHI subunit)
HP432_RS07205	COG0795	lipopolysaccharide-transporting ATPase activity
HP432_RS07210	COG0795	lipopolysaccharide-transporting ATPase activity
HP432_RS07220	COG1064	alcohol dehydrogenase
HP432_RS07230	COG0582	viral genome integration into host DNA
HP432_RS07250	COG2132	Multicopper oxidase
HP432_RS07270	COG0210	DNA helicase
HP432_RS07295	COG3539	Fimbrial protein
HP432_RS07300	COG2610	gluconate transmembrane transporter activity
HP432_RS07310	COG0246	Mannitol dehydrogenase
HP432_RS07315	COG2186	Transcriptional regulator
HP432_RS07335	COG0583	DNA-binding transcription factor activity
HP432_RS07340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HP432_RS07345	COG0700	Nucleoside recognition
HP432_RS07350	COG3366	ferrous iron transmembrane transporter activity
HP432_RS07360	COG0477	Major facilitator Superfamily
HP432_RS07375	COG1924	4 iron, 4 sulfur cluster binding
HP432_RS07380	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HP432_RS07385	COG2733	membrane
HP432_RS07390	COG2814	Major facilitator Superfamily
HP432_RS07410	COG0523	cobalamin synthesis protein
HP432_RS07415	COG2879	small protein
HP432_RS07420	COG1966	Carbon starvation protein
HP432_RS07425	COG0840	transmembrane signaling receptor activity
HP432_RS07430	COG2271	Major facilitator Superfamily
HP432_RS07435	COG1802	Transcriptional regulator
HP432_RS07440	COG1063	alcohol dehydrogenase
HP432_RS07455	COG1484	DNA-dependent DNA replication
HP432_RS07470	COG2966	Psort location CytoplasmicMembrane, score
HP432_RS07475	COG2197	response regulator
HP432_RS07480	COG2197	response regulator
HP432_RS07485	COG4114	ferric iron reductase
HP432_RS07515	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HP432_RS07520	COG0456	acetyltransferase
HP432_RS07525	COG1011	Hydrolase
HP432_RS07535	COG2823	Periplasmic or secreted lipoprotein
HP432_RS07545	COG4667	esterase of the alpha-beta hydrolase superfamily
HP432_RS07550	COG0084	hydrolase, TatD family'
HP432_RS07555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HP432_RS07560	COG1328	CTP reductase activity
HP432_RS07595	COG3726	membrane protein affecting hemolysin expression
HP432_RS07600	COG0560	Phosphoserine phosphatase
HP432_RS07605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HP432_RS07610	COG3172	ATPase kinase involved in NAD metabolism
HP432_RS07610	COG1056	cytidyltransferase-related domain
HP432_RS07620	COG0488	(ABC) transporter
HP432_RS07625	COG0741	lytic transglycosylase activity
HP432_RS07645	COG3708	Transcriptional regulator
HP432_RS07645	COG2207	Transcriptional regulator
HP432_RS07650	COG3045	CreA protein
HP432_RS07655	COG0745	RESPONSE REGULATOR receiver
HP432_RS07660	COG2205	protein histidine kinase activity
HP432_RS07665	COG4452	Inner membrane protein CreD
HP432_RS07670	COG0745	RESPONSE REGULATOR receiver
HP432_RS07680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HP432_RS07690	COG0527	aspartate kinase activity
HP432_RS07690	COG0460	homoserine dehydrogenase
HP432_RS07700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HP432_RS07715	COG1115	amino acid carrier protein
HP432_RS07720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HP432_RS07725	COG0521	Mo-molybdopterin cofactor biosynthetic process
HP432_RS07730	COG1584	GPR1 FUN34 yaaH family protein
HP432_RS07735	COG4735	regulation of single-species biofilm formation
HP432_RS07755	COG3385	transposase activity
HP432_RS07770	COG0583	DNA-binding transcription factor activity
HP432_RS07800	COG0196	riboflavin kinase activity
HP432_RS07815	COG1047	Peptidyl-prolyl cis-trans
HP432_RS07835	COG0505	Belongs to the CarA family
HP432_RS07840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HP432_RS07895	COG0644	oxidoreductase
HP432_RS07900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HP432_RS07905	COG2271	Major facilitator Superfamily
HP432_RS07920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HP432_RS07945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HP432_RS07950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HP432_RS07955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HP432_RS07960	COG0564	pseudouridine synthase activity
HP432_RS07970	COG0417	DNA replication proofreading
HP432_RS07975	COG0235	Class ii aldolase
HP432_RS07990	COG4977	sequence-specific DNA binding
HP432_RS07995	COG0586	Pfam SNARE associated Golgi protein
HP432_RS08005	COG1178	ABC-type Fe3 transport system permease component
HP432_RS08010	COG4143	(ABC) transporter
HP432_RS08025	COG2814	Major facilitator Superfamily
HP432_RS08040	COG0473	3-isopropylmalate dehydrogenase activity
HP432_RS08055	COG0583	DNA-binding transcription factor activity
HP432_RS08065	COG0028	Belongs to the TPP enzyme family
HP432_RS08070	COG0440	acetolactate synthase activity
HP432_RS08080	COG1609	Transcriptional regulator
HP432_RS08085	COG2001	Belongs to the MraZ family
HP432_RS08095	COG3116	cell division
HP432_RS08100	COG0768	penicillin binding
HP432_RS08105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HP432_RS08110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HP432_RS08120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HP432_RS08125	COG0772	Belongs to the SEDS family
HP432_RS08140	COG1181	Belongs to the D-alanine--D-alanine ligase family
HP432_RS08145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HP432_RS08150	COG0849	cell division
HP432_RS08155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HP432_RS08175	COG0494	nUDIX hydrolase
HP432_RS08190	COG0237	dephospho-CoA kinase activity
HP432_RS08200	COG1459	type II secretion system
HP432_RS08205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HP432_RS08210	COG4969	Belongs to the N-Me-Phe pilin family
HP432_RS08215	COG0157	Belongs to the NadC ModD family
HP432_RS08220	COG3023	N-Acetylmuramoyl-L-alanine amidase
HP432_RS08225	COG3725	Membrane protein required for beta-lactamase induction
HP432_RS08235	COG2186	Transcriptional regulator
HP432_RS08240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HP432_RS08245	COG0508	dehydrogenase complex catalyzes the overall conversion of
HP432_RS08250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HP432_RS08255	COG3064	Membrane
HP432_RS08260	COG1049	propionate catabolic process, 2-methylcitrate cycle
HP432_RS08285	COG2132	Multicopper oxidase
HP432_RS08290	COG4993	Dehydrogenase
HP432_RS08295	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HP432_RS08300	COG0288	reversible hydration of carbon dioxide
HP432_RS08305	COG1131	(ABC) transporter
HP432_RS08310	COG0842	Transport permease protein
HP432_RS08315	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS08320	COG0726	polysaccharide deacetylase
HP432_RS08330	COG5464	transposase or invertase
HP432_RS08345	COG3539	Fimbrial protein
HP432_RS08355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HP432_RS08360	COG0617	tRNA 3'-terminal CCA addition
HP432_RS08370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HP432_RS08380	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HP432_RS08385	COG1643	Atp-dependent helicase
HP432_RS08390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HP432_RS08395	COG4774	siderophore transport
HP432_RS08400	COG1120	ATPase activity
HP432_RS08405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HP432_RS08410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HP432_RS08435	COG2860	membrane
HP432_RS08440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HP432_RS08455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HP432_RS08460	COG3835	regulator
HP432_RS08470	COG1408	metallophosphoesterase
HP432_RS08485	COG0024	Methionine aminopeptidase
HP432_RS08510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HP432_RS08515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HP432_RS08520	COG0575	Belongs to the CDS family
HP432_RS08525	COG0750	zinc metalloprotease
HP432_RS08535	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HP432_RS08540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HP432_RS08565	COG0587	DNA-directed DNA polymerase activity
HP432_RS08580	COG0346	lactoylglutathione lyase activity
HP432_RS08590	COG4568	rho-dependent transcription termination
HP432_RS08600	COG4681	YaeQ
HP432_RS08605	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HP432_RS08610	COG3015	lipoprotein NlpE involved in copper resistance
HP432_RS08615	COG0791	NLP P60 protein
HP432_RS08625	COG1720	tRNA m6t6A37 methyltransferase activity
HP432_RS08635	COG1464	Belongs to the NlpA lipoprotein family
HP432_RS08640	COG2011	ABC-type metal ion transport system permease component
HP432_RS08645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HP432_RS08650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HP432_RS08685	COG0656	L-ascorbic acid biosynthetic process
HP432_RS08690	COG0583	DNA-binding transcription factor activity
HP432_RS08705	COG1388	LysM domain
HP432_RS08705	COG0741	lytic transglycosylase activity
HP432_RS08715	COG2226	methyltransferase
HP432_RS08725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HP432_RS08745	COG4104	PAAR repeat-containing protein
HP432_RS08750	COG3157	Type VI secretion system effector, Hcp
HP432_RS08780	COG3209	COG3209 Rhs family protein
HP432_RS08790	COG5433	transposase activity
HP432_RS08795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HP432_RS08805	COG1960	acyl-CoA dehydrogenase activity
HP432_RS08815	COG0121	glutamine amidotransferase
HP432_RS08820	COG3034	peptidoglycan biosynthetic process
HP432_RS08830	COG3077	Addiction module antitoxin, RelB DinJ family
HP432_RS08850	COG1677	Flagellar hook-basal body complex protein FliE
HP432_RS08860	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HP432_RS08880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HP432_RS08910	COG1815	bacterial-type flagellum-dependent cell motility
HP432_RS08915	COG1558	bacterial-type flagellum-dependent cell motility
HP432_RS08925	COG1749	Flagellar hook protein flgE
HP432_RS08930	COG4787	bacterial-type flagellum-dependent cell motility
HP432_RS08935	COG4786	Flagellar basal body rod
HP432_RS08960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HP432_RS08975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HP432_RS08980	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HP432_RS09005	COG1191	sigma factor activity
HP432_RS09010	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HP432_RS09025	COG2161	toxin-antitoxin pair type II binding
HP432_RS09035	COG0454	-acetyltransferase
HP432_RS09040	COG1690	Belongs to the RtcB family
HP432_RS09045	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HP432_RS09050	COG2195	Cleaves the N-terminal amino acid of tripeptides
HP432_RS09070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HP432_RS09105	COG2003	Belongs to the UPF0758 family
HP432_RS09135	COG2378	regulation of single-species biofilm formation
HP432_RS09145	COG3596	GTP binding
HP432_RS09165	COG0833	amino acid
HP432_RS09170	COG2040	homocysteine
HP432_RS09175	COG3842	ATPase activity
HP432_RS09195	COG3059	membrane
HP432_RS09205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HP432_RS09210	COG2207	Transcriptional regulator
HP432_RS09215	COG0247	lactate metabolic process
HP432_RS09220	COG1139	Iron-sulfur cluster binding protein
HP432_RS09225	COG1556	Lactate utilization protein
HP432_RS09250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HP432_RS09265	COG2200	EAL domain
HP432_RS09265	COG2771	luxR family
HP432_RS09270	COG0583	DNA-binding transcription factor activity
HP432_RS09280	COG0666	response to abiotic stimulus
HP432_RS09290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HP432_RS09295	COG1304	FMN binding
HP432_RS09305	COG0549	Belongs to the carbamate kinase family
HP432_RS09310	COG0402	S-adenosylhomocysteine deaminase activity
HP432_RS09315	COG1064	alcohol dehydrogenase
HP432_RS09330	COG1280	lysine exporter protein (LysE YggA)
HP432_RS09340	COG3829	transcription factor binding
HP432_RS09345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HP432_RS09350	COG0372	Belongs to the citrate synthase family
HP432_RS09355	COG2079	MmgE PrpD family protein
HP432_RS09360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HP432_RS09365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HP432_RS09370	COG0402	S-adenosylhomocysteine deaminase activity
HP432_RS09375	COG0583	DNA-binding transcription factor activity
HP432_RS09380	COG0288	reversible hydration of carbon dioxide
HP432_RS09390	COG2807	transmembrane transport
HP432_RS09395	COG0110	maltose O-acetyltransferase activity
HP432_RS09400	COG2223	nitrite transmembrane transporter activity
HP432_RS09405	COG3250	beta-galactosidase activity
HP432_RS09410	COG1609	Transcriptional regulator
HP432_RS09415	COG1414	Transcriptional regulator
HP432_RS09435	COG3971	2-oxopent-4-enoate hydratase activity
HP432_RS09450	COG2814	Major facilitator Superfamily
HP432_RS09455	COG3122	Protein conserved in bacteria
HP432_RS09485	COG1215	transferase activity, transferring glycosyl groups
HP432_RS09490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HP432_RS09495	COG4521	taurine ABC transporter
HP432_RS09500	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HP432_RS09505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HP432_RS09510	COG2175	clavaminate synthase activity
HP432_RS09515	COG0113	porphobilinogen synthase activity
HP432_RS09535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HP432_RS09540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HP432_RS09545	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HP432_RS09565	COG1181	Belongs to the D-alanine--D-alanine ligase family
HP432_RS09580	COG1785	Belongs to the alkaline phosphatase family
HP432_RS09590	COG3706	GGDEF domain
HP432_RS09595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HP432_RS09615	COG4126	flavin adenine dinucleotide binding
HP432_RS09640	COG1940	carbohydrate kinase activity
HP432_RS09645	COG2814	Major facilitator Superfamily
HP432_RS09650	COG0419	ATPase involved in DNA repair
HP432_RS09655	COG0420	3'-5' exonuclease activity
HP432_RS09660	COG0745	RESPONSE REGULATOR receiver
HP432_RS09665	COG5002	protein histidine kinase activity
HP432_RS09670	COG1114	Component of the transport system for branched-chain amino acids
HP432_RS09675	COG1113	amino acid transport
HP432_RS09680	COG0366	Alpha amylase catalytic
HP432_RS09700	COG1862	Preprotein translocase
HP432_RS09705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HP432_RS09710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HP432_RS09715	COG1403	HNH endonuclease
HP432_RS09720	COG3248	Nucleoside-binding outer membrane protein
HP432_RS09725	COG4238	major outer membrane lipoprotein
HP432_RS09735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HP432_RS09735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HP432_RS09750	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HP432_RS09755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HP432_RS09760	COG0667	Aldo Keto reductase
HP432_RS09770	COG0142	geranyltranstransferase activity
HP432_RS09785	COG0693	protein deglycase activity
HP432_RS09790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HP432_RS09800	COG2814	Major facilitator Superfamily
HP432_RS09810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HP432_RS09815	COG1845	cytochrome c oxidase, subunit III
HP432_RS09820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HP432_RS09825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HP432_RS09830	COG2223	nitrite transmembrane transporter activity
HP432_RS09835	COG3056	Lipoprotein
HP432_RS09840	COG0271	Belongs to the BolA IbaG family
HP432_RS09860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HP432_RS09865	COG0776	regulation of translation
HP432_RS09870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HP432_RS09875	COG1555	photosystem II stabilization
HP432_RS09890	COG4533	DNA binding
HP432_RS09900	COG1522	sequence-specific DNA binding
HP432_RS09905	COG1132	(ABC) transporter
HP432_RS09910	COG1132	(ABC) transporter
HP432_RS09915	COG0347	Belongs to the P(II) protein family
HP432_RS09920	COG0004	ammonium transporteR
HP432_RS09925	COG1946	Acyl-CoA thioesterase
HP432_RS09930	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HP432_RS09935	COG3695	enzyme binding
HP432_RS09945	COG5507	3-demethylubiquinone-9 3-methyltransferase
HP432_RS09960	COG0110	maltose O-acetyltransferase activity
HP432_RS09975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HP432_RS09980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS09985	COG1309	transcriptional regulator
HP432_RS09990	COG3264	Mechanosensitive ion channel
HP432_RS09990	COG1196	nuclear chromosome segregation
HP432_RS10000	COG3923	Primosomal replication protein n
HP432_RS10005	COG2832	Protein of unknown function (DUF454)
HP432_RS10015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HP432_RS10050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HP432_RS10055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HP432_RS10055	COG4651	solute:proton antiporter activity
HP432_RS10060	COG2223	nitrite transmembrane transporter activity
HP432_RS10065	COG0737	Belongs to the 5'-nucleotidase family
HP432_RS10070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HP432_RS10075	COG3735	TraB family
HP432_RS10080	COG3093	addiction module antidote protein HigA
HP432_RS10085	COG2217	Heavy metal translocating P-type atpase
HP432_RS10095	COG0531	amino acid
HP432_RS10100	COG0789	Transcriptional regulator
HP432_RS10105	COG1585	Membrane protein implicated in regulation of membrane protease activity
HP432_RS10110	COG0330	HflC and HflK could
HP432_RS10115	COG4619	ABC transporter
HP432_RS10120	COG0390	transport system, permease component
HP432_RS10125	COG3118	belongs to the thioredoxin family
HP432_RS10130	COG0300	oxidoreductase activity
HP432_RS10135	COG2755	lipolytic protein G-D-S-L family
HP432_RS10140	COG4181	ATPase activity
HP432_RS10145	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HP432_RS10155	COG0583	DNA-binding transcription factor activity
HP432_RS10165	COG1414	Transcriptional regulator
HP432_RS10170	COG3960	tartronate-semialdehyde synthase activity
HP432_RS10175	COG3622	Belongs to the hyi family
HP432_RS10180	COG2084	Dehydrogenase
HP432_RS10185	COG1953	Uracil, thiamine, allantoin
HP432_RS10210	COG1929	Belongs to the glycerate kinase type-1 family
HP432_RS10225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HP432_RS10230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HP432_RS10240	COG0549	Belongs to the carbamate kinase family
HP432_RS10245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HP432_RS10250	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HP432_RS10260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HP432_RS10270	COG1988	membrane-bound metal-dependent
HP432_RS10275	COG2501	S4 domain
HP432_RS10285	COG3539	Fimbrial protein
HP432_RS10290	COG3121	Chaperone
HP432_RS10295	COG3188	usher protein
HP432_RS10300	COG3539	Fimbrial protein
HP432_RS10305	COG3539	Fimbrial protein
HP432_RS10310	COG2197	response regulator
HP432_RS10320	COG2207	Transcriptional regulator
HP432_RS10330	COG4783	chaperone-mediated protein folding
HP432_RS10335	COG1215	transferase activity, transferring glycosyl groups
HP432_RS10340	COG5433	transposase activity
HP432_RS10355	COG4104	PAAR repeat-containing protein
HP432_RS10355	COG3209	COG3209 Rhs family protein
HP432_RS10365	COG3501	Rhs element vgr protein
HP432_RS10370	COG5002	protein histidine kinase activity
HP432_RS10375	COG0745	RESPONSE REGULATOR receiver
HP432_RS10380	COG1538	Outer membrane efflux protein
HP432_RS10385	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS10390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS10395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HP432_RS10400	COG1113	amino acid transport
HP432_RS10405	COG0668	transmembrane transport
HP432_RS10410	COG0778	Nitroreductase
HP432_RS10415	COG2315	Protein conserved in bacteria
HP432_RS10440	COG3385	transposase activity
HP432_RS10445	COG2977	Belongs to the P-Pant transferase superfamily
HP432_RS10450	COG4771	TonB-dependent receptor
HP432_RS10455	COG2382	esterase
HP432_RS10460	COG3251	PFAM MbtH domain protein
HP432_RS10465	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HP432_RS10465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HP432_RS10470	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HP432_RS10475	COG1120	ATPase activity
HP432_RS10480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HP432_RS10485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HP432_RS10495	COG4592	Periplasmic binding protein
HP432_RS10500	COG1169	isochorismate synthase
HP432_RS10505	COG1021	2,3-dihydroxybenzoate-AMP ligase
HP432_RS10510	COG3433	isochorismatase activity
HP432_RS10510	COG1535	isochorismatase
HP432_RS10515	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS10520	COG2050	protein possibly involved in aromatic compounds catabolism
HP432_RS10525	COG1966	Carbon starvation protein
HP432_RS10530	COG2879	small protein
HP432_RS10535	COG0371	Dehydrogenase
HP432_RS10540	COG0436	Aminotransferase
HP432_RS10545	COG1475	DNA binding
HP432_RS10550	COG3969	phosphoadenosine phosphosulfate
HP432_RS10555	COG0583	DNA-binding transcription factor activity
HP432_RS10560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HP432_RS10565	COG0450	alkyl hydroperoxide reductase
HP432_RS10570	COG3634	alkyl hydroperoxide reductase activity
HP432_RS10575	COG0589	response to stress
HP432_RS10580	COG1063	alcohol dehydrogenase
HP432_RS10585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HP432_RS10590	COG3719	Belongs to the RNase T2 family
HP432_RS10595	COG0471	metal ion transport
HP432_RS10610	COG3051	citrate lyase alpha subunit
HP432_RS10615	COG2301	Belongs to the HpcH HpaI aldolase family
HP432_RS10625	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HP432_RS10630	COG3290	protein histidine kinase activity
HP432_RS10635	COG4565	transcriptional regulatory protein
HP432_RS10640	COG3069	C4-dicarboxylate transmembrane transporter activity
HP432_RS10660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HP432_RS10665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HP432_RS10675	COG0583	DNA-binding transcription factor activity
HP432_RS10690	COG1686	Belongs to the peptidase S11 family
HP432_RS10695	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HP432_RS10700	COG0772	Belongs to the SEDS family
HP432_RS10705	COG0768	penicillin binding
HP432_RS10715	COG0799	negative regulation of ribosome biogenesis
HP432_RS10720	COG0406	alpha-ribazole phosphatase activity
HP432_RS10730	COG1466	dna polymerase III delta subunit
HP432_RS10745	COG2888	peptidyl-tyrosine sulfation
HP432_RS10750	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HP432_RS10760	COG2214	Heat shock protein DnaJ domain protein
HP432_RS10765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HP432_RS10775	COG2214	Heat shock protein DnaJ domain protein
HP432_RS10780	COG0443	Heat shock 70 kDa protein
HP432_RS10790	COG1126	abc transporter atp-binding protein
HP432_RS10795	COG0765	amino acid transport
HP432_RS10800	COG0765	amino acid transport
HP432_RS10805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS10810	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HP432_RS10815	COG4535	Mg2 and Co2 transporter CorC
HP432_RS10825	COG1702	phosphate starvation-inducible protein PhoH
HP432_RS10835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HP432_RS10875	COG0367	asparagine synthase
HP432_RS10880	COG0647	UMP catabolic process
HP432_RS10885	COG1846	Transcriptional regulator
HP432_RS10885	COG1940	carbohydrate kinase activity
HP432_RS10890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HP432_RS10900	COG1263	PTS System
HP432_RS10900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS10900	COG2190	(PTS) system
HP432_RS10920	COG0735	belongs to the Fur family
HP432_RS10930	COG0716	FMN binding
HP432_RS10940	COG0596	Alpha beta hydrolase
HP432_RS10945	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HP432_RS10950	COG0033	Phosphoglucomutase
HP432_RS10970	COG0531	amino acid
HP432_RS10975	COG1982	Orn Lys Arg decarboxylase major
HP432_RS10985	COG0745	RESPONSE REGULATOR receiver
HP432_RS10990	COG2205	protein histidine kinase activity
HP432_RS11020	COG3209	COG3209 Rhs family protein
HP432_RS11030	COG3209	COG3209 Rhs family protein
HP432_RS11080	COG3272	Protein of unknown function (DUF1722)
HP432_RS11085	COG0415	Belongs to the DNA photolyase family
HP432_RS11090	COG3104	oligopeptide transport
HP432_RS11095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HP432_RS11100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HP432_RS11105	COG1984	allophanate hydrolase subunit 2
HP432_RS11120	COG3180	Ammonia monooxygenase
HP432_RS11140	COG3121	Chaperone
HP432_RS11145	COG3188	usher protein
HP432_RS11150	COG3539	Fimbrial protein
HP432_RS11155	COG0372	Belongs to the citrate synthase family
HP432_RS11165	COG2009	succinate dehydrogenase
HP432_RS11170	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HP432_RS11175	COG1053	succinate dehydrogenase
HP432_RS11180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HP432_RS11185	COG0567	Dehydrogenase, E1 component
HP432_RS11190	COG0508	dehydrogenase complex catalyzes the overall conversion of
HP432_RS11200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HP432_RS11205	COG2188	Transcriptional regulator
HP432_RS11210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS11210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS11210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS11215	COG0383	alpha-mannosidase activity
HP432_RS11220	COG1271	oxidase subunit
HP432_RS11225	COG1294	oxidase, subunit
HP432_RS11230	COG4890	Cyd operon protein YbgT
HP432_RS11235	COG3790	cyd operon protein YbgE
HP432_RS11240	COG0824	Thioesterase
HP432_RS11245	COG0811	peptide transport
HP432_RS11250	COG0848	biopolymer transport protein
HP432_RS11255	COG3064	Membrane
HP432_RS11265	COG2885	chlorophyll binding
HP432_RS11270	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HP432_RS11315	COG3201	nicotinamide mononucleotide transporter
HP432_RS11320	COG1230	cation diffusion facilitator family transporter
HP432_RS11330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HP432_RS11340	COG2017	converts alpha-aldose to the beta-anomer
HP432_RS11350	COG1085	galactose-1-phosphate uridylyltransferase
HP432_RS11355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HP432_RS11360	COG1119	ATPase activity
HP432_RS11365	COG2005	Transcriptional regulator
HP432_RS11365	COG3585	molybdate ion transport
HP432_RS11375	COG0725	ABC transporter, periplasmic molybdate-binding protein
HP432_RS11380	COG4149	molybdate abc transporter
HP432_RS11385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HP432_RS11390	COG0561	phosphatase activity
HP432_RS11400	COG0583	DNA-binding transcription factor activity
HP432_RS11405	COG2828	Protein conserved in bacteria
HP432_RS11410	COG0471	metal ion transport
HP432_RS11415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HP432_RS11420	COG4677	pectinesterase activity
HP432_RS11425	COG1881	PFAM PEBP family protein
HP432_RS11430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HP432_RS11445	COG2226	methyltransferase
HP432_RS11450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HP432_RS11460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HP432_RS11470	COG0521	Mo-molybdopterin cofactor biosynthetic process
HP432_RS11480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HP432_RS11485	COG0314	molybdopterin synthase activity
HP432_RS11490	COG0670	Belongs to the BI1 family
HP432_RS11495	COG0670	Belongs to the BI1 family
HP432_RS11500	COG0392	lysyltransferase activity
HP432_RS11505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HP432_RS11510	COG3568	Endonuclease Exonuclease Phosphatase
HP432_RS11520	COG0842	Transport permease protein
HP432_RS11525	COG0842	Transport permease protein
HP432_RS11530	COG1131	(ABC) transporter
HP432_RS11540	COG1309	transcriptional regulator
HP432_RS11545	COG0513	Belongs to the DEAD box helicase family
HP432_RS11550	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HP432_RS11555	COG1199	ATP-dependent helicase activity
HP432_RS11560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HP432_RS11565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HP432_RS11575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HP432_RS11585	COG4774	siderophore transport
HP432_RS11600	COG0668	transmembrane transport
HP432_RS11605	COG1126	abc transporter atp-binding protein
HP432_RS11610	COG0765	amino acid transport
HP432_RS11615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS11625	COG5006	permease, DMT superfamily
HP432_RS11635	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HP432_RS11640	COG2194	sulfuric ester hydrolase activity
HP432_RS11650	COG1321	iron dependent repressor
HP432_RS11655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HP432_RS11660	COG1376	ErfK ybiS ycfS ynhG family protein
HP432_RS11665	COG0488	(ABC) transporter
HP432_RS11675	COG0561	phosphatase activity
HP432_RS11680	COG1882	Formate acetyltransferase
HP432_RS11685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HP432_RS11690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HP432_RS11695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HP432_RS11700	COG0303	'Molybdopterin
HP432_RS11705	COG1446	asparaginase
HP432_RS11730	COG2200	EAL domain
HP432_RS11755	COG2133	pyrroloquinoline quinone binding
HP432_RS11760	COG0625	glutathione transferase activity
HP432_RS11765	COG1686	Belongs to the peptidase S11 family
HP432_RS11770	COG1349	DNA-binding transcription factor activity
HP432_RS11775	COG0671	phosphoesterase, PA-phosphatase related
HP432_RS11780	COG2814	Major facilitator Superfamily
HP432_RS11790	COG0561	phosphatase activity
HP432_RS11795	COG0738	Major facilitator superfamily
HP432_RS11800	COG3226	Transcriptional regulator
HP432_RS11805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HP432_RS11845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HP432_RS11875	COG4695	Portal protein
HP432_RS11975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HP432_RS11985	COG0778	Nitroreductase
HP432_RS12000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HP432_RS12005	COG3842	ATPase activity
HP432_RS12010	COG1176	ABC-type spermidine putrescine transport system, permease component I
HP432_RS12015	COG1177	transmembrane transport
HP432_RS12030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS12035	COG4160	amino acid transport
HP432_RS12040	COG4215	(ABC) transporter
HP432_RS12045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS12050	COG1126	abc transporter atp-binding protein
HP432_RS12065	COG3023	N-Acetylmuramoyl-L-alanine amidase
HP432_RS12070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HP432_RS12075	COG0702	epimerase
HP432_RS12080	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HP432_RS12085	COG0028	Belongs to the TPP enzyme family
HP432_RS12090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HP432_RS12100	COG2431	L-lysine efflux transmembrane transporter activity
HP432_RS12115	COG3593	DNA synthesis involved in DNA repair
HP432_RS12120	COG2990	Protein conserved in bacteria
HP432_RS12125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HP432_RS12130	COG1136	(ABC) transporter
HP432_RS12130	COG0577	efflux transmembrane transporter activity
HP432_RS12135	COG1278	Cold shock
HP432_RS12145	COG0542	response to heat
HP432_RS12165	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HP432_RS12170	COG4988	ABC transporter
HP432_RS12175	COG0492	ferredoxin-NADP+ reductase activity
HP432_RS12180	COG1522	sequence-specific DNA binding
HP432_RS12185	COG1178	ABC-type Fe3 transport system permease component
HP432_RS12185	COG1674	ftsk spoiiie
HP432_RS12195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HP432_RS12205	COG0243	molybdopterin cofactor binding
HP432_RS12210	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS12215	COG3302	dmso reductase anchor subunit
HP432_RS12220	COG1335	isochorismatase
HP432_RS12235	COG0531	amino acid
HP432_RS12240	COG0583	DNA-binding transcription factor activity
HP432_RS12245	COG2249	NAD(P)H dehydrogenase (quinone) activity
HP432_RS12250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HP432_RS12255	COG1882	Formate acetyltransferase
HP432_RS12260	COG2116	formate transmembrane transporter activity
HP432_RS12265	COG1944	ATP diphosphatase activity
HP432_RS12270	COG2323	membrane
HP432_RS12285	COG0501	Belongs to the peptidase M48B family
HP432_RS12295	COG0539	negative regulation of cytoplasmic translation
HP432_RS12305	COG2333	competence protein COMEC
HP432_RS12305	COG0658	competence protein
HP432_RS12310	COG1132	(ABC) transporter
HP432_RS12315	COG1663	tetraacyldisaccharide 4'-kinase activity
HP432_RS12320	COG3214	Protein conserved in bacteria
HP432_RS12335	COG3173	Aminoglycoside phosphotransferase
HP432_RS12340	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HP432_RS12345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HP432_RS12355	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HP432_RS12365	COG2989	Protein conserved in bacteria
HP432_RS12370	COG3108	Peptidase M15
HP432_RS12375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HP432_RS12380	COG1448	Aminotransferase
HP432_RS12385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HP432_RS12400	COG0308	aminopeptidase N
HP432_RS12405	COG1116	anion transmembrane transporter activity
HP432_RS12410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HP432_RS12420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HP432_RS12425	COG0431	NADPH-dependent FMN reductase
HP432_RS12445	COG3121	Chaperone
HP432_RS12450	COG3188	usher protein
HP432_RS12455	COG3539	Fimbrial protein
HP432_RS12460	COG3539	Fimbrial protein
HP432_RS12465	COG3539	Fimbrial protein
HP432_RS12470	COG3121	Chaperone
HP432_RS12485	COG3217	Mosc domain protein beta barrel domain protein
HP432_RS12485	COG0633	Ferredoxin
HP432_RS12495	COG0488	(ABC) transporter
HP432_RS12500	COG2995	paraquat-inducible protein a
HP432_RS12505	COG3008	intermembrane lipid transfer
HP432_RS12505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HP432_RS12510	COG3009	Protein conserved in bacteria
HP432_RS12515	COG3130	regulation of translation
HP432_RS12525	COG1067	ATP-dependent peptidase activity
HP432_RS12535	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HP432_RS12535	COG2885	chlorophyll binding
HP432_RS12545	COG3070	regulator of competence-specific genes
HP432_RS12550	COG1289	transmembrane transporter activity
HP432_RS12555	COG3304	Inner membrane component domain
HP432_RS12560	COG0210	DNA helicase
HP432_RS12575	COG1832	CoA-binding protein
HP432_RS12590	COG1254	Belongs to the acylphosphatase family
HP432_RS12595	COG2920	part of a sulfur-relay system
HP432_RS12600	COG0670	Belongs to the BI1 family
HP432_RS12610	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HP432_RS12615	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HP432_RS12620	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HP432_RS12625	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HP432_RS12630	COG1999	signal sequence binding
HP432_RS12635	COG1773	rubredoxin
HP432_RS12640	COG1271	oxidase subunit
HP432_RS12645	COG1294	oxidase, subunit
HP432_RS12665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HP432_RS12670	COG1596	polysaccharide export
HP432_RS12675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HP432_RS12700	COG1278	Cold shock
HP432_RS12705	COG1278	Cold shock
HP432_RS12725	COG0348	domain, Protein
HP432_RS12730	COG2198	Histidine kinase
HP432_RS12730	COG2205	protein histidine kinase activity
HP432_RS12730	COG0784	Response regulator, receiver
HP432_RS12735	COG1879	ABC-type sugar transport system periplasmic component
HP432_RS12740	COG0745	RESPONSE REGULATOR receiver
HP432_RS12745	COG3005	denitrification pathway
HP432_RS12750	COG0243	molybdopterin cofactor binding
HP432_RS12790	COG3729	General stress protein
HP432_RS12795	COG2233	PERMEase
HP432_RS12820	COG1335	isochorismatase
HP432_RS12830	COG1309	transcriptional regulator
HP432_RS12835	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HP432_RS12835	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HP432_RS12835	COG0506	proline dehydrogenase activity
HP432_RS12845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HP432_RS12855	COG2822	iron ion transport
HP432_RS12860	COG2837	iron assimilation
HP432_RS12865	COG1702	phosphate starvation-inducible protein PhoH
HP432_RS12870	COG3658	cytochrome
HP432_RS12875	COG1215	transferase activity, transferring glycosyl groups
HP432_RS12880	COG0726	polysaccharide deacetylase
HP432_RS12880	COG1649	PFAM Uncharacterised BCR, COG1649
HP432_RS12885	COG0457	Tetratricopeptide repeat
HP432_RS12890	COG3706	GGDEF domain
HP432_RS12925	COG3381	protein complex oligomerization
HP432_RS12935	COG1462	curli production assembly transport component CsgG
HP432_RS12950	COG2197	response regulator
HP432_RS12975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HP432_RS12980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HP432_RS12995	COG2943	transferase activity, transferring hexosyl groups
HP432_RS13000	COG5645	(Lipo)protein
HP432_RS13015	COG1560	Kdo2-lipid A biosynthetic process
HP432_RS13025	COG2353	YceI-like domain
HP432_RS13030	COG3038	cytochrome b561
HP432_RS13065	COG2999	glutathione oxidoreductase activity
HP432_RS13075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HP432_RS13085	COG0673	inositol 2-dehydrogenase activity
HP432_RS13090	COG0728	peptidoglycan biosynthetic process
HP432_RS13095	COG3418	PFAM FlgN family protein
HP432_RS13100	COG2747	anti-sigma28 factor FlgM
HP432_RS13105	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HP432_RS13110	COG1815	bacterial-type flagellum-dependent cell motility
HP432_RS13115	COG1558	bacterial-type flagellum-dependent cell motility
HP432_RS13120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HP432_RS13125	COG1749	Flagellar hook protein flgE
HP432_RS13130	COG4787	bacterial-type flagellum-dependent cell motility
HP432_RS13135	COG4786	Flagellar basal body rod
HP432_RS13150	COG3951	Flagellar rod assembly protein muramidase FlgJ
HP432_RS13150	COG1705	Flagellar rod assembly protein muramidase FlgJ
HP432_RS13155	COG1256	bacterial-type flagellum assembly
HP432_RS13160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HP432_RS13165	COG1530	ribonuclease E activity
HP432_RS13170	COG0564	pseudouridine synthase activity
HP432_RS13175	COG0424	maF-like protein
HP432_RS13180	COG1399	metal-binding, possibly nucleic acid-binding protein
HP432_RS13200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HP432_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS13215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HP432_RS13220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HP432_RS13225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HP432_RS13235	COG0470	DNA polymerase III
HP432_RS13240	COG0084	hydrolase, TatD family'
HP432_RS13245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS13245	COG1263	PTS System
HP432_RS13250	COG4773	Receptor
HP432_RS13255	COG0537	adenosine 5'-monophosphoramidase activity
HP432_RS13260	COG5633	Lipoprotein
HP432_RS13265	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HP432_RS13285	COG1252	NADH dehydrogenase
HP432_RS13290	COG3134	Outer membrane lipoprotein
HP432_RS13295	COG1309	transcriptional regulator
HP432_RS13305	COG1388	LysM domain
HP432_RS13305	COG1376	ErfK ybiS ycfS ynhG family protein
HP432_RS13310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HP432_RS13315	COG4763	Acyl-transferase
HP432_RS13320	COG4591	ABC-type transport system involved in lipoprotein release permease component
HP432_RS13325	COG1136	(ABC) transporter
HP432_RS13330	COG4591	ABC-type transport system involved in lipoprotein release permease component
HP432_RS13340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HP432_RS13345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HP432_RS13355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HP432_RS13360	COG1177	transmembrane transport
HP432_RS13380	COG2850	peptidyl-arginine hydroxylation
HP432_RS13385	COG2205	protein histidine kinase activity
HP432_RS13390	COG0745	RESPONSE REGULATOR receiver
HP432_RS13395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HP432_RS13415	COG1187	pseudouridine synthase activity
HP432_RS13420	COG0538	isocitrate dehydrogenase activity
HP432_RS13435	COG5562	phage envelope protein
HP432_RS13440	COG0789	Transcriptional regulator
HP432_RS13445	COG2200	EAL domain
HP432_RS13540	COG2894	cell division
HP432_RS13565	COG0179	Fumarylacetoacetate (FAA) hydrolase
HP432_RS13585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HP432_RS13590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HP432_RS13605	COG2719	SpoVR family
HP432_RS13615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HP432_RS13625	COG1619	proteins homologs of microcin C7 resistance protein MccF
HP432_RS13635	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HP432_RS13640	COG2261	transglycosylase associated protein
HP432_RS13665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HP432_RS13665	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HP432_RS13665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS13670	COG1461	Dihydroxyacetone kinase
HP432_RS13675	COG2376	Dihydroxyacetone kinase
HP432_RS13680	COG3284	Transcriptional regulator
HP432_RS13685	COG3468	outer membrane autotransporter barrel domain protein
HP432_RS13690	COG0012	GTP binding
HP432_RS13705	COG0659	secondary active sulfate transmembrane transporter activity
HP432_RS13710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HP432_RS13735	COG2890	protein-(glutamine-N5) methyltransferase activity
HP432_RS13740	COG3094	Invasion gene expression up-regulator, SirB
HP432_RS13745	COG2912	Transglutaminase-like superfamily
HP432_RS13770	COG0387	Pfam Sodium calcium exchanger
HP432_RS13775	COG4572	Cation transport regulator
HP432_RS13780	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HP432_RS13785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HP432_RS13790	COG4932	domain protein
HP432_RS13795	COG2197	response regulator
HP432_RS13800	COG3850	Histidine kinase
HP432_RS13805	COG2223	nitrite transmembrane transporter activity
HP432_RS13810	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HP432_RS13815	COG1140	nitrate reductase beta subunit
HP432_RS13820	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HP432_RS13825	COG2181	nitrate reductase activity
HP432_RS13855	COG0788	formyltetrahydrofolate deformylase activity
HP432_RS13865	COG1752	Esterase of the alpha-beta hydrolase superfamily
HP432_RS13870	COG0745	RESPONSE REGULATOR receiver
HP432_RS13875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HP432_RS13885	COG1435	thymidine kinase activity
HP432_RS13895	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS13895	COG1454	alcohol dehydrogenase
HP432_RS13900	COG2095	MarC family integral membrane protein
HP432_RS13910	COG4166	transmembrane transport
HP432_RS13915	COG0601	transmembrane transport
HP432_RS13920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HP432_RS13925	COG0444	Belongs to the ABC transporter superfamily
HP432_RS13930	COG4608	Belongs to the ABC transporter superfamily
HP432_RS13950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HP432_RS13955	COG2350	Protein conserved in bacteria
HP432_RS13960	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HP432_RS13965	COG1607	acyl-coa hydrolase
HP432_RS13985	COG3047	cAMP biosynthetic process
HP432_RS13990	COG3685	Protein conserved in bacteria
HP432_RS13995	COG3685	Protein conserved in bacteria
HP432_RS14000	COG3729	General stress protein
HP432_RS14015	COG0135	phosphoribosylanthranilate isomerase activity
HP432_RS14015	COG0134	indole-3-glycerol-phosphate synthase activity
HP432_RS14020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HP432_RS14020	COG0512	Glutamine amidotransferase of anthranilate synthase
HP432_RS14025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HP432_RS14035	COG0613	PHP domain protein
HP432_RS14040	COG0009	L-threonylcarbamoyladenylate synthase
HP432_RS14045	COG4907	membrane protein (DUF2207)
HP432_RS14050	COG1187	pseudouridine synthase activity
HP432_RS14055	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HP432_RS14060	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS14065	COG0616	signal peptide processing
HP432_RS14075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HP432_RS14080	COG0583	DNA-binding transcription factor activity
HP432_RS14100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HP432_RS14110	COG0671	phosphoesterase, PA-phosphatase related
HP432_RS14115	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HP432_RS14120	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HP432_RS14130	COG0023	Translation Initiation Factor
HP432_RS14140	COG1349	DNA-binding transcription factor activity
HP432_RS14150	COG5001	Diguanylate cyclase
HP432_RS14165	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HP432_RS14165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HP432_RS14170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HP432_RS14175	COG2852	Protein conserved in bacteria
HP432_RS14180	COG4172	Belongs to the ABC transporter superfamily
HP432_RS14185	COG4172	Belongs to the ABC transporter superfamily
HP432_RS14190	COG4171	peptide transport system, permease
HP432_RS14195	COG4168	peptide transport system, permease
HP432_RS14200	COG4166	transmembrane transport
HP432_RS14210	COG0531	amino acid
HP432_RS14220	COG0174	glutamine synthetase
HP432_RS14225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HP432_RS14230	COG1396	sequence-specific DNA binding
HP432_RS14230	COG1917	Cupin 2, conserved barrel domain protein
HP432_RS14235	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS14240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HP432_RS14245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HP432_RS14250	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HP432_RS14255	COG1842	Phage shock protein A
HP432_RS14265	COG1983	PspC domain protein
HP432_RS14275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HP432_RS14280	COG0366	Alpha amylase catalytic
HP432_RS14295	COG1653	transport
HP432_RS14300	COG1175	transmembrane transport
HP432_RS14305	COG0395	ABC-type sugar transport system, permease component
HP432_RS14310	COG1063	alcohol dehydrogenase
HP432_RS14315	COG1082	Xylose isomerase domain protein TIM barrel
HP432_RS14320	COG0673	inositol 2-dehydrogenase activity
HP432_RS14325	COG1554	hydrolase, family 65, central catalytic
HP432_RS14330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HP432_RS14335	COG3842	ATPase activity
HP432_RS14345	COG1609	Transcriptional regulator
HP432_RS14350	COG3106	COG3106 Predicted ATPase
HP432_RS14360	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HP432_RS14365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HP432_RS14370	COG4948	Mandelate Racemase Muconate Lactonizing
HP432_RS14375	COG2866	Carboxypeptidase
HP432_RS14390	COG1073	alpha beta
HP432_RS14410	COG4166	transmembrane transport
HP432_RS14415	COG0668	transmembrane transport
HP432_RS14420	COG3182	Iron-regulated membrane protein
HP432_RS14425	COG0589	response to stress
HP432_RS14430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HP432_RS14435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HP432_RS14440	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HP432_RS14445	COG1473	amidohydrolase
HP432_RS14450	COG1473	amidohydrolase
HP432_RS14455	COG0583	DNA-binding transcription factor activity
HP432_RS14460	COG2840	Smr protein MutS2
HP432_RS14465	COG3706	GGDEF domain
HP432_RS14475	COG0513	Belongs to the DEAD box helicase family
HP432_RS14485	COG0582	viral genome integration into host DNA
HP432_RS14505	COG3723	Recombinational DNA repair protein, rece pathway
HP432_RS14510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HP432_RS14520	COG1484	DNA-dependent DNA replication
HP432_RS14525	COG1846	Transcriptional regulator
HP432_RS14560	COG1403	HNH endonuclease
HP432_RS14565	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HP432_RS14570	COG0484	heat shock protein binding
HP432_RS14610	COG3772	lysozyme
HP432_RS14620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HP432_RS14625	COG1475	DNA binding
HP432_RS14645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HP432_RS14650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HP432_RS14665	COG0589	response to stress
HP432_RS14670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HP432_RS14675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HP432_RS14675	COG1013	pyruvate-flavodoxin oxidoreductase activity
HP432_RS14675	COG0674	pyruvate-flavodoxin oxidoreductase activity
HP432_RS14675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HP432_RS14680	COG3042	response to heat
HP432_RS14685	COG3187	Heat shock protein
HP432_RS14690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HP432_RS14695	COG2911	Protein conserved in bacteria
HP432_RS14705	COG3784	Protein of unknown function (DUF1318)
HP432_RS14710	COG2207	Transcriptional regulator
HP432_RS14715	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS14720	COG3733	amine oxidase
HP432_RS14725	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS14725	COG2030	dehydratase
HP432_RS14730	COG3396	Phenylacetate-CoA oxygenase
HP432_RS14735	COG3460	Phenylacetate-CoA oxygenase
HP432_RS14740	COG3396	Phenylacetate-CoA oxygenase
HP432_RS14745	COG2151	metal-sulfur cluster biosynthetic enzyme
HP432_RS14750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HP432_RS14755	COG1024	Enoyl-CoA hydratase
HP432_RS14760	COG1024	Enoyl-CoA hydratase
HP432_RS14765	COG1250	3-hydroxyacyl-CoA dehydrogenase
HP432_RS14770	COG2050	protein possibly involved in aromatic compounds catabolism
HP432_RS14775	COG0183	Belongs to the thiolase family
HP432_RS14780	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HP432_RS14785	COG3327	negative regulation of DNA-templated transcription, initiation
HP432_RS14790	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HP432_RS14815	COG0667	Aldo Keto reductase
HP432_RS14825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HP432_RS14845	COG2267	carboxylic ester hydrolase activity
HP432_RS14850	COG0671	phosphoesterase, PA-phosphatase related
HP432_RS14850	COG2453	phosphatase
HP432_RS14860	COG1643	Atp-dependent helicase
HP432_RS14865	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HP432_RS14870	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS14875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HP432_RS14880	COG3038	cytochrome b561
HP432_RS14895	COG0840	transmembrane signaling receptor activity
HP432_RS14900	COG0583	DNA-binding transcription factor activity
HP432_RS14905	COG5383	Protein conserved in bacteria
HP432_RS14915	COG2841	Protein conserved in bacteria
HP432_RS14920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HP432_RS14925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HP432_RS14930	COG1275	C4-dicarboxylate transporter malic acid transport protein
HP432_RS14935	COG0500	methyltransferase
HP432_RS14950	COG0675	Transposase, IS605 OrfB family
HP432_RS14955	COG3135	benzoate transporter
HP432_RS14960	COG1396	sequence-specific DNA binding
HP432_RS14965	COG0826	peptidase U32
HP432_RS14975	COG1724	mRNA binding
HP432_RS14980	COG1598	PFAM Uncharacterised protein family UPF0150
HP432_RS14985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HP432_RS14990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HP432_RS14995	COG3842	ATPase activity
HP432_RS15000	COG1176	ABC-type spermidine putrescine transport system, permease component I
HP432_RS15005	COG1177	transmembrane transport
HP432_RS15030	COG3238	Protein conserved in bacteria
HP432_RS15035	COG1247	-acetyltransferase
HP432_RS15040	COG2130	NADP-dependent
HP432_RS15045	COG1802	Transcriptional regulator
HP432_RS15050	COG4772	TonB-dependent receptor
HP432_RS15055	COG3391	amine dehydrogenase activity
HP432_RS15060	COG1113	amino acid transport
HP432_RS15070	COG1403	HNH endonuclease
HP432_RS15090	COG2207	Transcriptional regulator
HP432_RS15105	COG3772	lysozyme
HP432_RS15115	COG1278	Cold shock
HP432_RS15140	COG5562	phage envelope protein
HP432_RS15150	COG4220	transposase activity
HP432_RS15200	COG5301	cellulose 1,4-beta-cellobiosidase activity
HP432_RS15205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HP432_RS15210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HP432_RS15230	COG0246	Mannitol dehydrogenase
HP432_RS15240	COG1802	Transcriptional regulator
HP432_RS15245	COG4221	oxidoreductase activity
HP432_RS15250	COG0339	signal peptide processing
HP432_RS15255	COG1546	Belongs to the CinA family
HP432_RS15260	COG3111	PFAM Bacterial OB fold (BOF) protein
HP432_RS15265	COG3706	GGDEF domain
HP432_RS15275	COG2814	Major facilitator Superfamily
HP432_RS15280	COG0697	spore germination
HP432_RS15285	COG2188	Transcriptional regulator
HP432_RS15295	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HP432_RS15300	COG1447	Phosphotransferase system cellobiose-specific component IIA
HP432_RS15320	COG2723	6-phospho-beta-galactosidase activity
HP432_RS15330	COG4977	sequence-specific DNA binding
HP432_RS15335	COG1846	Transcriptional regulator
HP432_RS15355	COG0583	DNA-binding transcription factor activity
HP432_RS15360	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS15365	COG2066	Belongs to the glutaminase family
HP432_RS15375	COG2199	diguanylate cyclase activity
HP432_RS15385	COG3781	membrane
HP432_RS15455	COG1396	sequence-specific DNA binding
HP432_RS15460	COG3550	peptidyl-serine autophosphorylation
HP432_RS15485	COG3539	Fimbrial protein
HP432_RS15490	COG0243	molybdopterin cofactor binding
HP432_RS15505	COG3119	arylsulfatase activity
HP432_RS15510	COG0641	radical SAM
HP432_RS15520	COG4178	(ABC) transporter
HP432_RS15525	COG4771	TonB-dependent receptor
HP432_RS15530	COG0612	Peptidase, M16
HP432_RS15535	COG0076	glutamate decarboxylase activity
HP432_RS15540	COG0531	amino acid
HP432_RS15550	COG3706	GGDEF domain
HP432_RS15555	COG2199	diguanylate cyclase activity
HP432_RS15555	COG2200	EAL domain
HP432_RS15555	COG2202	Pas domain
HP432_RS15560	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HP432_RS15565	COG0747	negative chemotaxis
HP432_RS15570	COG0601	transmembrane transport
HP432_RS15575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HP432_RS15580	COG0444	Belongs to the ABC transporter superfamily
HP432_RS15590	COG1764	response to oxidative stress
HP432_RS15610	COG1064	alcohol dehydrogenase
HP432_RS15615	COG3093	addiction module antidote protein HigA
HP432_RS15620	COG2864	formate dehydrogenase
HP432_RS15625	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS15635	COG0697	spore germination
HP432_RS15640	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HP432_RS15660	COG2223	nitrite transmembrane transporter activity
HP432_RS15665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HP432_RS15670	COG1140	nitrate reductase beta subunit
HP432_RS15675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HP432_RS15680	COG2181	nitrate reductase activity
HP432_RS15685	COG0384	phenazine biosynthesis protein PhzF
HP432_RS15690	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HP432_RS15695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HP432_RS15705	COG5433	transposase activity
HP432_RS15740	COG0625	glutathione transferase activity
HP432_RS15760	COG2026	Addiction module toxin, RelE StbE family
HP432_RS15765	COG3077	Addiction module antitoxin, RelB DinJ family
HP432_RS15780	COG2801	Transposase and inactivated derivatives
HP432_RS15800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HP432_RS15815	COG0243	molybdopterin cofactor binding
HP432_RS15820	COG0243	molybdopterin cofactor binding
HP432_RS15825	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS15830	COG3302	dmso reductase anchor subunit
HP432_RS15835	COG3381	protein complex oligomerization
HP432_RS15845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HP432_RS15850	COG1940	carbohydrate kinase activity
HP432_RS15855	COG0583	DNA-binding transcription factor activity
HP432_RS15860	COG2814	Major facilitator Superfamily
HP432_RS15875	COG3591	Belongs to the peptidase S1B family
HP432_RS15890	COG0628	permease
HP432_RS15895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HP432_RS15900	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HP432_RS15910	COG0531	amino acid
HP432_RS15920	COG3136	membrane protein required for alginate biosynthesis
HP432_RS15925	COG0745	RESPONSE REGULATOR receiver
HP432_RS15930	COG2205	protein histidine kinase activity
HP432_RS15940	COG0114	fumarate hydratase activity
HP432_RS15945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HP432_RS15945	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HP432_RS15950	COG1482	cell wall glycoprotein biosynthetic process
HP432_RS15955	COG5339	Protein conserved in bacteria
HP432_RS15970	COG3250	beta-galactosidase activity
HP432_RS15975	COG1309	transcriptional regulator
HP432_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS15985	COG1609	Transcriptional regulator
HP432_RS15990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS15990	COG1263	PTS System
HP432_RS15995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HP432_RS16005	COG0673	inositol 2-dehydrogenase activity
HP432_RS16045	COG4659	FMN binding
HP432_RS16055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HP432_RS16060	COG3104	oligopeptide transport
HP432_RS16065	COG0625	glutathione transferase activity
HP432_RS16070	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HP432_RS16085	COG3895	Periplasmic Protein
HP432_RS16095	COG3133	Outer membrane lipoprotein
HP432_RS16110	COG1566	PFAM secretion protein HlyD family protein
HP432_RS16115	COG1289	transmembrane transporter activity
HP432_RS16120	COG2032	superoxide dismutase activity
HP432_RS16125	COG4989	oxidoreductase activity
HP432_RS16130	COG3313	Fe-S protein
HP432_RS16135	COG1309	transcriptional regulator
HP432_RS16140	COG1902	pentaerythritol trinitrate reductase activity
HP432_RS16145	COG0346	lactoylglutathione lyase activity
HP432_RS16155	COG1201	RNA secondary structure unwinding
HP432_RS16160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HP432_RS16170	COG0791	NLP P60 protein
HP432_RS16175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HP432_RS16180	COG2814	Major facilitator Superfamily
HP432_RS16195	COG0583	DNA-binding transcription factor activity
HP432_RS16200	COG2814	Major facilitator Superfamily
HP432_RS16205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HP432_RS16210	COG0307	riboflavin synthase, alpha
HP432_RS16220	COG3468	outer membrane autotransporter barrel domain protein
HP432_RS16240	COG4529	Protein conserved in bacteria
HP432_RS16250	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HP432_RS16255	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS16280	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS16290	COG0469	pyruvate kinase activity
HP432_RS16295	COG4238	major outer membrane lipoprotein
HP432_RS16300	COG1376	ErfK ybiS ycfS ynhG family protein
HP432_RS16315	COG0719	Fe-S assembly protein
HP432_RS16320	COG0396	ATPase activity
HP432_RS16325	COG0719	Fe-S assembly protein
HP432_RS16330	COG0316	Belongs to the HesB IscA family
HP432_RS16340	COG2050	protein possibly involved in aromatic compounds catabolism
HP432_RS16345	COG0247	lactate metabolic process
HP432_RS16345	COG0277	FAD linked oxidase domain protein
HP432_RS16350	COG0628	permease
HP432_RS16365	COG0738	Major facilitator superfamily
HP432_RS16370	COG2271	Major facilitator Superfamily
HP432_RS16390	COG4670	ketone body catabolic process
HP432_RS16395	COG1960	acyl-CoA dehydrogenase activity
HP432_RS16400	COG2207	Transcriptional regulator
HP432_RS16400	COG1917	Cupin 2, conserved barrel domain protein
HP432_RS16405	COG2086	electron transfer activity
HP432_RS16410	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HP432_RS16415	COG0644	oxidoreductase
HP432_RS16420	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HP432_RS16425	COG0318	PFAM AMP-dependent synthetase and ligase
HP432_RS16430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HP432_RS16430	COG0574	Belongs to the PEP-utilizing enzyme family
HP432_RS16440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HP432_RS16445	COG4256	Hemin uptake protein
HP432_RS16460	COG2200	EAL domain
HP432_RS16465	COG0791	NLP P60 protein
HP432_RS16475	COG0386	Belongs to the glutathione peroxidase family
HP432_RS16490	COG0072	phenylalanine-tRNA ligase activity
HP432_RS16490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HP432_RS16535	COG3137	Salt-induced outer membrane protein
HP432_RS16540	COG1105	Belongs to the carbohydrate kinase PfkB family
HP432_RS16550	COG3001	Fructosamine kinase
HP432_RS16560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HP432_RS16565	COG1988	membrane-bound metal-dependent
HP432_RS16585	COG0753	catalase activity
HP432_RS16595	COG1486	melibiose metabolic process
HP432_RS16600	COG2169	Transcriptional regulator
HP432_RS16600	COG1917	Cupin 2, conserved barrel domain protein
HP432_RS16605	COG1447	Phosphotransferase system cellobiose-specific component IIA
HP432_RS16610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HP432_RS16615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HP432_RS16620	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HP432_RS16630	COG0322	excinuclease ABC activity
HP432_RS16640	COG3678	ATP-independent chaperone mediated protein folding
HP432_RS16670	COG0708	Exodeoxyribonuclease III
HP432_RS16675	COG0398	Pfam SNARE associated Golgi protein
HP432_RS16685	COG0398	Pfam SNARE associated Golgi protein
HP432_RS16690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HP432_RS16695	COG4134	Bacterial extracellular solute-binding protein
HP432_RS16700	COG4135	transport system, permease component
HP432_RS16705	COG4136	ATPase activity
HP432_RS16710	COG2897	thiosulfate sulfurtransferase activity
HP432_RS16715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HP432_RS16720	COG0494	nUDIX hydrolase
HP432_RS16730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HP432_RS16740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HP432_RS16750	COG0778	Nitroreductase
HP432_RS16755	COG0616	signal peptide processing
HP432_RS16760	COG0252	asparaginase activity
HP432_RS16765	COG1335	isochorismatase
HP432_RS16770	COG2814	Major facilitator Superfamily
HP432_RS16775	COG1349	DNA-binding transcription factor activity
HP432_RS16780	COG0667	Aldo Keto reductase
HP432_RS16800	COG0191	fructose-bisphosphate aldolase activity
HP432_RS16805	COG1063	alcohol dehydrogenase
HP432_RS16830	COG3139	Protein of unknown function (DUF1315)
HP432_RS16840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HP432_RS16845	COG0676	glucose-6-phosphate 1-epimerase activity
HP432_RS16850	COG0656	L-ascorbic acid biosynthetic process
HP432_RS16855	COG3713	MltA-interacting MipA family protein
HP432_RS16860	COG2766	serine protein kinase
HP432_RS16870	COG2199	diguanylate cyclase activity
HP432_RS16875	COG2199	diguanylate cyclase activity
HP432_RS16880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HP432_RS16895	COG2207	Transcriptional regulator
HP432_RS16900	COG2807	transmembrane transport
HP432_RS16905	COG3189	MarR family transcriptional regulator
HP432_RS16910	COG3042	response to heat
HP432_RS16915	COG2199	diguanylate cyclase activity
HP432_RS16915	COG2203	Gaf domain
HP432_RS16930	COG2261	transglycosylase associated protein
HP432_RS16940	COG3615	Tellurite resistance protein tehB
HP432_RS16950	COG2826	transposase and inactivated derivatives, IS30 family
HP432_RS16955	COG0583	DNA-binding transcription factor activity
HP432_RS16960	COG0473	3-isopropylmalate dehydrogenase activity
HP432_RS16965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HP432_RS16970	COG4638	Rieske (2fe-2S)
HP432_RS16975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HP432_RS16980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HP432_RS16985	COG0318	PFAM AMP-dependent synthetase and ligase
HP432_RS16990	COG3065	identical protein binding
HP432_RS16995	COG1214	PFAM Peptidase M22, glycoprotease
HP432_RS17000	COG1199	ATP-dependent helicase activity
HP432_RS17005	COG0251	oxidation-reduction process
HP432_RS17020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HP432_RS17030	COG1760	l-serine dehydratase
HP432_RS17040	COG1253	flavin adenine dinucleotide binding
HP432_RS17045	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS17045	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS17050	COG3715	PTS system
HP432_RS17055	COG3716	PTS system mannose fructose sorbose family IID component
HP432_RS17070	COG2226	methyltransferase
HP432_RS17100	COG1414	Transcriptional regulator
HP432_RS17105	COG2814	Major facilitator Superfamily
HP432_RS17115	COG0793	Belongs to the peptidase S41A family
HP432_RS17125	COG1956	GAF domain-containing protein
HP432_RS17130	COG2995	paraquat-inducible protein a
HP432_RS17135	COG3008	intermembrane lipid transfer
HP432_RS17155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HP432_RS17165	COG1276	copper resistance
HP432_RS17170	COG2372	response to copper ion
HP432_RS17180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HP432_RS17185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HP432_RS17190	COG1770	oligopeptidase
HP432_RS17195	COG2979	Protein of unknown function (DUF533)
HP432_RS17205	COG3141	response to X-ray
HP432_RS17215	COG0800	Aldolase
HP432_RS17220	COG0129	dihydroxy-acid dehydratase activity
HP432_RS17225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HP432_RS17230	COG1737	Transcriptional regulator
HP432_RS17235	COG0469	pyruvate kinase activity
HP432_RS17240	COG1560	Kdo2-lipid A biosynthetic process
HP432_RS17245	COG0739	heme binding
HP432_RS17250	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HP432_RS17260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HP432_RS17290	COG0217	transcriptional regulatory protein
HP432_RS17295	COG0494	nUDIX hydrolase
HP432_RS17305	COG1335	isochorismatase
HP432_RS17310	COG1801	Protein of unknown function DUF72
HP432_RS17315	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HP432_RS17330	COG0243	molybdopterin cofactor binding
HP432_RS17335	COG3005	denitrification pathway
HP432_RS17345	COG3102	Protein conserved in bacteria
HP432_RS17355	COG3755	Protein conserved in bacteria
HP432_RS17365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HP432_RS17370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HP432_RS17375	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HP432_RS17380	COG0745	RESPONSE REGULATOR receiver
HP432_RS17385	COG2201	protein-glutamate methylesterase activity
HP432_RS17390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HP432_RS17395	COG0840	transmembrane signaling receptor activity
HP432_RS17400	COG0840	transmembrane signaling receptor activity
HP432_RS17405	COG0835	chemotaxis
HP432_RS17410	COG2198	Histidine kinase
HP432_RS17410	COG0643	Histidine kinase
HP432_RS17415	COG1360	Flagellar Motor Protein
HP432_RS17420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HP432_RS17435	COG0589	response to stress
HP432_RS17445	COG1877	trehalose-phosphatase activity
HP432_RS17450	COG1172	Belongs to the binding-protein-dependent transport system permease family
HP432_RS17455	COG1129	ABC transporter
HP432_RS17460	COG1879	ABC-type sugar transport system periplasmic component
HP432_RS17465	COG1528	Iron-storage protein
HP432_RS17485	COG1528	Iron-storage protein
HP432_RS17495	COG0814	amino acid
HP432_RS17500	COG3318	Belongs to the UPF0149 family
HP432_RS17500	COG3012	SEC-C Motif Domain Protein
HP432_RS17520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HP432_RS17525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HP432_RS17550	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HP432_RS17555	COG3318	Belongs to the UPF0149 family
HP432_RS17555	COG3012	SEC-C Motif Domain Protein
HP432_RS17665	COG2197	response regulator
HP432_RS17680	COG2197	response regulator
HP432_RS17710	COG1191	sigma factor activity
HP432_RS17720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HP432_RS17725	COG1516	flagellar protein fliS
HP432_RS17735	COG0366	Alpha amylase catalytic
HP432_RS17745	COG2391	methyltransferase activity
HP432_RS17750	COG0425	Belongs to the sulfur carrier protein TusA family
HP432_RS17755	COG2135	peptidase activity
HP432_RS17765	COG1766	The M ring may be actively involved in energy transduction
HP432_RS17770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HP432_RS17775	COG1317	bacterial-type flagellum organization
HP432_RS17780	COG1157	protein secretion by the type III secretion system
HP432_RS17785	COG2882	bacterial-type flagellum organization
HP432_RS17790	COG3144	bacterial-type flagellum assembly
HP432_RS17795	COG1580	Controls the rotational direction of flagella during chemotaxis
HP432_RS17800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HP432_RS17805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HP432_RS17810	COG3190	flagellar
HP432_RS17815	COG1338	Plays a role in the flagellum-specific transport system
HP432_RS17820	COG1987	bacterial-type flagellum assembly
HP432_RS17825	COG1684	flagellar biosynthetic protein fliR
HP432_RS17830	COG2197	response regulator
HP432_RS17855	COG5475	Uncharacterized small protein (DUF2158)
HP432_RS17860	COG2354	Protein conserved in bacteria
HP432_RS17865	COG0697	spore germination
HP432_RS17870	COG3727	T/G mismatch-specific endonuclease activity
HP432_RS17875	COG0270	DNA (cytosine-5-)-methyltransferase activity
HP432_RS17890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HP432_RS17915	COG2205	protein histidine kinase activity
HP432_RS17920	COG0745	RESPONSE REGULATOR receiver
HP432_RS17925	COG2351	hydroxyisourate hydrolase activity
HP432_RS17940	COG3443	Belongs to the bacterial solute-binding protein 9 family
HP432_RS17945	COG3038	cytochrome b561
HP432_RS17965	COG0582	viral genome integration into host DNA
HP432_RS17990	COG0477	Major facilitator Superfamily
HP432_RS17995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HP432_RS18000	COG0217	transcriptional regulatory protein
HP432_RS18010	COG0534	Mate efflux family protein
HP432_RS18020	COG0583	DNA-binding transcription factor activity
HP432_RS18025	COG0583	DNA-binding transcription factor activity
HP432_RS18050	COG1349	DNA-binding transcription factor activity
HP432_RS18055	COG0698	ribose 5-phosphate isomerase
HP432_RS18060	COG3775	system Galactitol-specific IIC component
HP432_RS18065	COG3414	Phosphotransferase system galactitol-specific IIB component
HP432_RS18070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS18080	COG1376	ErfK ybiS ycfS ynhG family protein
HP432_RS18095	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HP432_RS18115	COG1289	transmembrane transporter activity
HP432_RS18125	COG1686	Belongs to the peptidase S11 family
HP432_RS18130	COG2246	polysaccharide biosynthetic process
HP432_RS18135	COG0463	Glycosyl transferase, family 2
HP432_RS18185	COG2925	Exonuclease
HP432_RS18190	COG0425	Belongs to the sulfur carrier protein TusA family
HP432_RS18195	COG2391	methyltransferase activity
HP432_RS18200	COG0531	amino acid
HP432_RS18210	COG0583	DNA-binding transcription factor activity
HP432_RS18215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HP432_RS18220	COG4115	mRNA cleavage
HP432_RS18225	COG2161	toxin-antitoxin pair type II binding
HP432_RS18240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HP432_RS18250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HP432_RS18250	COG0131	Imidazoleglycerol-phosphate dehydratase
HP432_RS18255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HP432_RS18285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HP432_RS18290	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HP432_RS18335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HP432_RS18340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HP432_RS18355	COG0438	transferase activity, transferring glycosyl groups
HP432_RS18360	COG2327	Polysaccharide pyruvyl transferase
HP432_RS18365	COG2244	polysaccharide biosynthetic process
HP432_RS18370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HP432_RS18375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HP432_RS18380	COG0662	Cupin 2, conserved barrel domain protein
HP432_RS18380	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HP432_RS18385	COG0297	glycogen (starch) synthase activity
HP432_RS18390	COG1051	belongs to the nudix hydrolase family
HP432_RS18395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HP432_RS18400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HP432_RS18405	COG0110	maltose O-acetyltransferase activity
HP432_RS18410	COG1216	Glycosyl transferase, family 2
HP432_RS18420	COG0438	transferase activity, transferring glycosyl groups
HP432_RS18425	COG1045	serine acetyltransferase
HP432_RS18430	COG0463	Glycosyl transferase, family 2
HP432_RS18435	COG0489	protein tyrosine kinase activity
HP432_RS18435	COG3206	protein involved in exopolysaccharide biosynthesis
HP432_RS18440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HP432_RS18445	COG1596	polysaccharide export
HP432_RS18455	COG1253	flavin adenine dinucleotide binding
HP432_RS18460	COG2982	Protein involved in outer membrane biogenesis
HP432_RS18470	COG0572	uridine kinase
HP432_RS18475	COG5002	protein histidine kinase activity
HP432_RS18475	COG5001	Diguanylate cyclase
HP432_RS18475	COG3447	MASE1 domain protein
HP432_RS18480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HP432_RS18485	COG0443	Heat shock 70 kDa protein
HP432_RS18490	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HP432_RS18495	COG3779	Protein conserved in bacteria
HP432_RS18500	COG0631	protein serine/threonine phosphatase activity
HP432_RS18505	COG4245	von Willebrand factor, type A
HP432_RS18540	COG2205	protein histidine kinase activity
HP432_RS18545	COG0745	RESPONSE REGULATOR receiver
HP432_RS18570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HP432_RS18580	COG1070	Carbohydrate kinase
HP432_RS18605	COG1069	ribulokinase activity
HP432_RS18615	COG1830	Aldolase
HP432_RS18620	COG2211	Major facilitator Superfamily
HP432_RS18625	COG1397	ADP-ribosylglycohydrolase
HP432_RS18630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HP432_RS18635	COG2188	Transcriptional regulator
HP432_RS18640	COG3757	hydrolase, family 25
HP432_RS18645	COG0351	phosphomethylpyrimidine kinase
HP432_RS18665	COG5455	response to cobalt ion
HP432_RS18670	COG3539	Fimbrial protein
HP432_RS18675	COG3188	usher protein
HP432_RS18680	COG3121	Chaperone
HP432_RS18685	COG3539	Fimbrial protein
HP432_RS18695	COG0489	protein tyrosine kinase activity
HP432_RS18705	COG3831	ATPase activity
HP432_RS18710	COG3831	ATPase activity
HP432_RS18720	COG0714	Associated with various cellular activities
HP432_RS18725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HP432_RS18730	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HP432_RS18735	COG4715	Zinc finger, swim domain protein
HP432_RS18740	COG4808	Protein conserved in bacteria
HP432_RS18745	COG4807	Protein conserved in bacteria
HP432_RS18750	COG3279	Response regulator of the LytR AlgR family
HP432_RS18755	COG3275	phosphorelay sensor kinase activity
HP432_RS18760	COG0789	Transcriptional regulator
HP432_RS18770	COG1174	glycine betaine transport
HP432_RS18775	COG1125	glycine betaine transport
HP432_RS18780	COG1174	glycine betaine transport
HP432_RS18785	COG1732	Glycine betaine
HP432_RS18790	COG1472	Belongs to the glycosyl hydrolase 3 family
HP432_RS18795	COG0277	FAD linked oxidase domain protein
HP432_RS18800	COG1686	Belongs to the peptidase S11 family
HP432_RS18810	COG0586	Pfam SNARE associated Golgi protein
HP432_RS18815	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS18830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HP432_RS18840	COG1346	cytolysis
HP432_RS18850	COG2949	membrane
HP432_RS18860	COG0493	'glutamate synthase
HP432_RS18865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HP432_RS18865	COG0167	dihydroorotate dehydrogenase activity
HP432_RS18870	COG4211	Belongs to the binding-protein-dependent transport system permease family
HP432_RS18875	COG1129	ABC transporter
HP432_RS18880	COG1879	ABC-type sugar transport system periplasmic component
HP432_RS18885	COG1609	Transcriptional regulator
HP432_RS18890	COG2311	Membrane
HP432_RS18905	COG4771	TonB-dependent receptor
HP432_RS18910	COG0833	amino acid
HP432_RS18915	COG0583	DNA-binding transcription factor activity
HP432_RS18920	COG2855	membrane
HP432_RS18930	COG1522	sequence-specific DNA binding
HP432_RS18930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HP432_RS18935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HP432_RS18950	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HP432_RS18950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS18950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS18955	COG1105	Belongs to the carbohydrate kinase PfkB family
HP432_RS18960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS18960	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS18965	COG2814	Major facilitator Superfamily
HP432_RS18980	COG0246	Mannitol dehydrogenase
HP432_RS18985	COG0523	cobalamin synthesis protein
HP432_RS18990	COG0671	phosphoesterase, PA-phosphatase related
HP432_RS18995	COG0791	NLP P60 protein
HP432_RS19000	COG2200	EAL domain
HP432_RS19005	COG4166	transmembrane transport
HP432_RS19010	COG4174	ABC transporter (Permease)
HP432_RS19015	COG4239	(ABC) transporter, permease
HP432_RS19020	COG4172	Belongs to the ABC transporter superfamily
HP432_RS19030	COG2814	Major facilitator Superfamily
HP432_RS19035	COG1187	pseudouridine synthase activity
HP432_RS19040	COG1061	Type III restriction enzyme res subunit
HP432_RS19060	COG3083	sulfuric ester hydrolase activity
HP432_RS19070	COG3468	outer membrane autotransporter barrel domain protein
HP432_RS19075	COG2197	response regulator
HP432_RS19080	COG3088	subunit of a heme lyase
HP432_RS19080	COG4235	cytochrome complex assembly
HP432_RS19085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HP432_RS19090	COG1138	Cytochrome C-type biogenesis protein
HP432_RS19100	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HP432_RS19105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HP432_RS19110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HP432_RS19115	COG4133	protoheme IX ABC transporter activity
HP432_RS19120	COG3005	denitrification pathway
HP432_RS19125	COG3043	anaerobic respiration
HP432_RS19130	COG0348	domain, Protein
HP432_RS19135	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS19145	COG3062	negative regulation of establishment of protein localization
HP432_RS19150	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS19150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS19170	COG4615	Cyclic peptide transporter
HP432_RS19175	COG3145	DNA-N1-methyladenine dioxygenase activity
HP432_RS19180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HP432_RS19180	COG2169	Transcriptional regulator
HP432_RS19185	COG1477	protein flavinylation
HP432_RS19195	COG0642	Histidine kinase
HP432_RS19195	COG2198	Histidine kinase
HP432_RS19200	COG2197	response regulator
HP432_RS19205	COG0784	Response regulator, receiver
HP432_RS19205	COG2205	protein histidine kinase activity
HP432_RS19210	COG3852	Histidine kinase
HP432_RS19220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HP432_RS19225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HP432_RS19230	COG2031	fatty acid transporter
HP432_RS19235	COG0183	Belongs to the thiolase family
HP432_RS19240	COG4676	Protein conserved in bacteria
HP432_RS19245	COG5445	Predicted secreted protein (DUF2300)
HP432_RS19250	COG2373	Large extracellular alpha-helical protein
HP432_RS19255	COG3234	Protein of unknown function (DUF1175)
HP432_RS19260	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HP432_RS19265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HP432_RS19275	COG3468	outer membrane autotransporter barrel domain protein
HP432_RS19285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HP432_RS19290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HP432_RS19295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HP432_RS19300	COG3642	lipopolysaccharide core region biosynthetic process
HP432_RS19310	COG0584	glycerophosphoryl diester phosphodiesterase
HP432_RS19315	COG2271	Major facilitator Superfamily
HP432_RS19320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HP432_RS19330	COG0247	lactate metabolic process
HP432_RS19335	COG5464	transposase or invertase
HP432_RS19350	COG2271	Major facilitator Superfamily
HP432_RS19360	COG1414	Transcriptional regulator
HP432_RS19430	COG0318	PFAM AMP-dependent synthetase and ligase
HP432_RS19440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HP432_RS19455	COG1169	isochorismate synthase
HP432_RS19460	COG4575	ribosome binding
HP432_RS19465	COG2153	protein acetylation
HP432_RS19480	COG0457	Tetratricopeptide repeat
HP432_RS19490	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HP432_RS19495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HP432_RS19505	COG0839	Belongs to the complex I subunit 6 family
HP432_RS19520	COG1034	ATP synthesis coupled electron transport
HP432_RS19525	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HP432_RS19530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HP432_RS19550	COG0583	DNA-binding transcription factor activity
HP432_RS19555	COG0436	Aminotransferase
HP432_RS19565	COG0471	metal ion transport
HP432_RS19565	COG0490	domain, Protein
HP432_RS19570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HP432_RS19585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HP432_RS19590	COG0857	belongs to the CobB CobQ family
HP432_RS19590	COG0280	phosphate acetyltransferase
HP432_RS19595	COG1288	antiporter activity
HP432_RS19600	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HP432_RS19605	COG0622	Phosphoesterase
HP432_RS19610	COG0625	glutathione transferase activity
HP432_RS19615	COG0625	glutathione transferase activity
HP432_RS19620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HP432_RS19625	COG1090	epimerase
HP432_RS19630	COG5464	transposase or invertase
HP432_RS19635	COG4598	ABC transporter
HP432_RS19640	COG4160	amino acid transport
HP432_RS19645	COG4215	(ABC) transporter
HP432_RS19650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS19655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS19660	COG0163	prenyltransferase activity
HP432_RS19665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HP432_RS19670	COG1286	toxin biosynthetic process
HP432_RS19675	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HP432_RS19680	COG0285	dihydrofolate synthase activity
HP432_RS19690	COG0586	Pfam SNARE associated Golgi protein
HP432_RS19700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HP432_RS19715	COG2814	Major facilitator Superfamily
HP432_RS19720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HP432_RS19735	COG3101	peptidyl-lysine hydroxylation
HP432_RS19740	COG0730	response to heat
HP432_RS19755	COG2890	protein-(glutamine-N5) methyltransferase activity
HP432_RS19770	COG3539	Fimbrial protein
HP432_RS19775	COG3539	Fimbrial protein
HP432_RS19780	COG3539	Fimbrial protein
HP432_RS19785	COG3121	Chaperone
HP432_RS19790	COG3188	usher protein
HP432_RS19795	COG3539	Fimbrial protein
HP432_RS19800	COG2062	phosphohistidine phosphatase, SixA
HP432_RS19815	COG3691	Protein conserved in bacteria
HP432_RS19820	COG2067	long-chain fatty acid transport protein
HP432_RS19840	COG2853	Lipoprotein
HP432_RS19845	COG2116	formate transmembrane transporter activity
HP432_RS19855	COG0583	DNA-binding transcription factor activity
HP432_RS19860	COG2610	gluconate transmembrane transporter activity
HP432_RS19870	COG0477	Major facilitator Superfamily
HP432_RS19875	COG1566	PFAM secretion protein HlyD family protein
HP432_RS19880	COG2197	response regulator
HP432_RS19885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HP432_RS19885	COG0784	Response regulator, receiver
HP432_RS19885	COG2198	Histidine kinase
HP432_RS19885	COG2205	protein histidine kinase activity
HP432_RS19890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HP432_RS19895	COG0679	Auxin Efflux Carrier
HP432_RS19900	COG0028	Belongs to the TPP enzyme family
HP432_RS19925	COG1560	Kdo2-lipid A biosynthetic process
HP432_RS19935	COG0436	Aminotransferase
HP432_RS19940	COG3275	phosphorelay sensor kinase activity
HP432_RS19945	COG3279	Response regulator of the LytR AlgR family
HP432_RS19950	COG2207	Transcriptional regulator
HP432_RS19955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS19955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS19955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HP432_RS19960	COG1363	Peptidase, m42
HP432_RS19965	COG0006	proline dipeptidase activity
HP432_RS19970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS19975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HP432_RS20000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HP432_RS20005	COG2200	EAL domain
HP432_RS20005	COG2199	diguanylate cyclase activity
HP432_RS20020	COG3415	Transposase
HP432_RS20025	COG3415	Transposase
HP432_RS20055	COG0583	DNA-binding transcription factor activity
HP432_RS20065	COG2211	Major facilitator Superfamily
HP432_RS20070	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HP432_RS20080	COG0583	DNA-binding transcription factor activity
HP432_RS20085	COG0385	Bile acid
HP432_RS20090	COG3530	Putative quorum-sensing-regulated virulence factor
HP432_RS20110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HP432_RS20115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS20120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HP432_RS20125	COG2190	(PTS) system
HP432_RS20140	COG3831	ATPase activity
HP432_RS20140	COG4884	unkown
HP432_RS20145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HP432_RS20150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HP432_RS20155	COG4208	sulfate ABC transporter
HP432_RS20160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HP432_RS20165	COG4150	thiosulfate binding
HP432_RS20170	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS20185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS20185	COG1263	PTS System
HP432_RS20190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HP432_RS20195	COG2837	iron assimilation
HP432_RS20215	COG0860	N-Acetylmuramoyl-L-alanine amidase
HP432_RS20225	COG2207	Transcriptional regulator
HP432_RS20230	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HP432_RS20235	COG4816	utilization protein
HP432_RS20245	COG4303	Ethanolamine ammonia lyase large subunit
HP432_RS20250	COG4819	ethanolamine utilization protein
HP432_RS20255	COG3192	ethanolamine utilization protein
HP432_RS20260	COG1454	alcohol dehydrogenase
HP432_RS20265	COG4820	ethanolamine utilization protein (EutJ)
HP432_RS20270	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS20275	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HP432_RS20280	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HP432_RS20285	COG0280	phosphate acetyltransferase
HP432_RS20290	COG4812	Cobalamin adenosyltransferase
HP432_RS20295	COG4766	ethanolamine catabolic process
HP432_RS20300	COG4917	ethanolamine utilization protein
HP432_RS20305	COG4810	utilization protein
HP432_RS20310	COG0280	phosphate acetyltransferase
HP432_RS20310	COG0281	malic enzyme
HP432_RS20315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HP432_RS20320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HP432_RS20325	COG5342	invasion associated locus B
HP432_RS20335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS20335	COG0493	'glutamate synthase
HP432_RS20340	COG3850	Histidine kinase
HP432_RS20345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HP432_RS20360	COG1393	Belongs to the ArsC family
HP432_RS20375	COG0400	carboxylic ester hydrolase activity
HP432_RS20385	COG2321	neutral zinc metallopeptidase
HP432_RS20395	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HP432_RS20405	COG2716	regulation of RNA biosynthetic process
HP432_RS20410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HP432_RS20415	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS20425	COG0650	Formate hydrogenlyase subunit 4
HP432_RS20430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HP432_RS20435	COG4237	Hydrogenase 4 membrane
HP432_RS20445	COG3261	NADH dehydrogenase
HP432_RS20445	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HP432_RS20450	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HP432_RS20455	COG3260	NADH ubiquinone oxidoreductase 20
HP432_RS20465	COG3604	Transcriptional regulator
HP432_RS20470	COG2116	formate transmembrane transporter activity
HP432_RS20475	COG0628	permease
HP432_RS20480	COG4783	chaperone-mediated protein folding
HP432_RS20485	COG1393	Belongs to the ArsC family
HP432_RS20495	COG2233	PERMEase
HP432_RS20510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HP432_RS20515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HP432_RS20520	COG0248	Ppx GppA phosphatase
HP432_RS20525	COG2200	EAL domain
HP432_RS20540	COG3133	Outer membrane lipoprotein
HP432_RS20555	COG0517	IMP dehydrogenase activity
HP432_RS20555	COG0516	GMP reductase activity
HP432_RS20565	COG1645	bacterial-type flagellum-dependent swarming motility
HP432_RS20580	COG2976	Protein conserved in bacteria
HP432_RS20610	COG4953	penicillin-binding protein 1C
HP432_RS20615	COG2373	Large extracellular alpha-helical protein
HP432_RS20620	COG2897	thiosulfate sulfurtransferase activity
HP432_RS20635	COG2975	iron-sulfur cluster assembly
HP432_RS20640	COG0633	Ferredoxin
HP432_RS20660	COG0822	iron-sulfur transferase activity
HP432_RS20680	COG0483	inositol monophosphate 1-phosphatase activity
HP432_RS20685	COG1073	alpha beta
HP432_RS20690	COG3711	transcriptional antiterminator
HP432_RS20695	COG2814	Major facilitator Superfamily
HP432_RS20700	COG0583	DNA-binding transcription factor activity
HP432_RS20705	COG4638	Rieske (2fe-2S)
HP432_RS20730	COG2259	Doxx family
HP432_RS20735	COG2017	converts alpha-aldose to the beta-anomer
HP432_RS20740	COG1063	alcohol dehydrogenase
HP432_RS20745	COG1172	Belongs to the binding-protein-dependent transport system permease family
HP432_RS20750	COG1129	ABC transporter
HP432_RS20755	COG1879	ABC-type sugar transport system periplasmic component
HP432_RS20760	COG0457	Tetratricopeptide repeat
HP432_RS20765	COG1940	carbohydrate kinase activity
HP432_RS20775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HP432_RS20775	COG1017	nitric oxide dioxygenase activity
HP432_RS20780	COG0347	Belongs to the P(II) protein family
HP432_RS20785	COG2204	response regulator
HP432_RS20790	COG3170	Tfp pilus assembly protein FimV
HP432_RS20795	COG2205	protein histidine kinase activity
HP432_RS20800	COG0047	phosphoribosylformylglycinamidine synthase activity
HP432_RS20800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HP432_RS20815	COG0560	Phosphoserine phosphatase
HP432_RS20820	COG1737	Transcriptional regulator
HP432_RS20825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS20840	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HP432_RS20860	COG0681	Belongs to the peptidase S26 family
HP432_RS20870	COG3086	response to oxidative stress
HP432_RS20875	COG3026	antisigma factor binding
HP432_RS20880	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HP432_RS20885	COG1595	DNA-templated transcription, initiation
HP432_RS20895	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HP432_RS20905	COG0513	Belongs to the DEAD box helicase family
HP432_RS20910	COG0583	DNA-binding transcription factor activity
HP432_RS20935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HP432_RS20940	COG3118	belongs to the thioredoxin family
HP432_RS20950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HP432_RS20950	COG0045	succinate-CoA ligase (ADP-forming) activity
HP432_RS20950	COG1042	CoA-binding domain protein
HP432_RS20955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HP432_RS20960	COG5544	Lipoprotein
HP432_RS20965	COG0477	Major facilitator Superfamily
HP432_RS20990	COG0542	response to heat
HP432_RS21000	COG0564	pseudouridine synthase activity
HP432_RS21005	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HP432_RS21010	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HP432_RS21020	COG1605	Chorismate mutase
HP432_RS21020	COG0077	Prephenate dehydratase
HP432_RS21025	COG0287	Prephenate dehydrogenase
HP432_RS21025	COG1605	Chorismate mutase
HP432_RS21030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HP432_RS21045	COG2199	diguanylate cyclase activity
HP432_RS21050	COG2885	chlorophyll binding
HP432_RS21075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HP432_RS21080	COG4137	Cytochrome C assembly protein
HP432_RS21085	COG4536	flavin adenine dinucleotide binding
HP432_RS21100	COG0497	DNA recombination
HP432_RS21105	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HP432_RS21115	COG2867	negative regulation of translational initiation
HP432_RS21130	COG0582	viral genome integration into host DNA
HP432_RS21140	COG1475	DNA binding
HP432_RS21175	COG0579	oxidoreductase
HP432_RS21180	COG1012	belongs to the aldehyde dehydrogenase family
HP432_RS21185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HP432_RS21190	COG1113	amino acid transport
HP432_RS21195	COG1802	Transcriptional regulator
HP432_RS21200	COG1652	LysM domain
HP432_RS21205	COG0401	homolog of Blt101
HP432_RS21210	COG0640	Transcriptional regulator
HP432_RS21215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HP432_RS21220	COG2916	Histone family protein nucleoid-structuring protein H-NS
HP432_RS21235	COG4575	ribosome binding
HP432_RS21240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HP432_RS21250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HP432_RS21255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HP432_RS21260	COG4175	Glycine betaine
HP432_RS21265	COG4176	ABC-type proline glycine betaine transport system permease component
HP432_RS21270	COG2113	Glycine betaine
HP432_RS21275	COG2814	Major facilitator Superfamily
HP432_RS21280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HP432_RS21290	COG1846	Transcriptional regulator
HP432_RS21295	COG1566	PFAM secretion protein HlyD family protein
HP432_RS21300	COG2814	Major facilitator Superfamily
HP432_RS21315	COG1238	metal cluster binding
HP432_RS21320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HP432_RS21355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HP432_RS21375	COG1546	Belongs to the CinA family
HP432_RS21385	COG2951	lytic endotransglycosylase activity
HP432_RS21390	COG3730	PTS system glucitol sorbitol-specific
HP432_RS21395	COG3732	PTS system glucitol sorbitol-specific
HP432_RS21405	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS21410	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS21415	COG1349	DNA-binding transcription factor activity
HP432_RS21440	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HP432_RS21445	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS21450	COG1609	Transcriptional regulator
HP432_RS21455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HP432_RS21455	COG1263	PTS System
HP432_RS21460	COG2723	6-phospho-beta-galactosidase activity
HP432_RS21465	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HP432_RS21475	COG3260	NADH ubiquinone oxidoreductase 20
HP432_RS21480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HP432_RS21485	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HP432_RS21485	COG3261	NADH dehydrogenase
HP432_RS21490	COG0650	Formate hydrogenlyase subunit 4
HP432_RS21495	COG0651	ATP synthesis coupled electron transport
HP432_RS21500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS21510	COG0375	protein maturation
HP432_RS21515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HP432_RS21520	COG0298	carbon dioxide binding
HP432_RS21525	COG0409	Hydrogenase expression formation protein
HP432_RS21530	COG0309	Hydrogenase expression formation protein (HypE)
HP432_RS21535	COG3604	Transcriptional regulator
HP432_RS21555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HP432_RS21560	COG1349	DNA-binding transcription factor activity
HP432_RS21565	COG2084	Dehydrogenase
HP432_RS21570	COG3395	kinase activity
HP432_RS21575	COG0235	Class ii aldolase
HP432_RS21580	COG3622	Belongs to the hyi family
HP432_RS21585	COG2610	gluconate transmembrane transporter activity
HP432_RS21590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HP432_RS21595	COG4942	peptidase
HP432_RS21595	COG1388	LysM domain
HP432_RS21650	COG2234	aminopeptidase activity
HP432_RS21655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HP432_RS21660	COG1518	maintenance of DNA repeat elements
HP432_RS21675	COG1857	crispr-associated protein
HP432_RS21690	COG1203	CRISPR-associated helicase, Cas3
HP432_RS21700	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HP432_RS21710	COG0720	synthase
HP432_RS21715	COG0644	oxidoreductase
HP432_RS21720	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HP432_RS21725	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HP432_RS21730	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HP432_RS21735	COG2086	electron transfer activity
HP432_RS21740	COG0477	Major facilitator Superfamily
HP432_RS21745	COG0277	FAD linked oxidase domain protein
HP432_RS21750	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS21755	COG2223	nitrite transmembrane transporter activity
HP432_RS21760	COG1070	Carbohydrate kinase
HP432_RS21765	COG0602	queuosine metabolic process
HP432_RS21775	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HP432_RS21790	COG3956	TIGRFAM MazG family protein
HP432_RS21795	COG2337	Toxic component of a toxin-antitoxin (TA) module
HP432_RS21800	COG2336	PFAM SpoVT AbrB
HP432_RS21805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HP432_RS21815	COG2205	protein histidine kinase activity
HP432_RS21815	COG4999	Histidine kinase
HP432_RS21815	COG3850	Histidine kinase
HP432_RS21815	COG3437	response regulator, receiver
HP432_RS21820	COG4948	Mandelate Racemase Muconate Lactonizing
HP432_RS21825	COG4948	Mandelate Racemase Muconate Lactonizing
HP432_RS21830	COG2271	Major facilitator Superfamily
HP432_RS21835	COG0716	FMN binding
HP432_RS21840	COG0564	pseudouridine synthase activity
HP432_RS21845	COG3098	single-species biofilm formation
HP432_RS21860	COG1611	Belongs to the LOG family
HP432_RS21865	COG0814	amino acid
HP432_RS21870	COG1760	l-serine dehydratase
HP432_RS21880	COG1454	alcohol dehydrogenase
HP432_RS21885	COG0235	Class ii aldolase
HP432_RS21890	COG0738	Major facilitator superfamily
HP432_RS21900	COG1070	Carbohydrate kinase
HP432_RS21905	COG1070	Carbohydrate kinase
HP432_RS21915	COG1349	DNA-binding transcription factor activity
HP432_RS21925	COG2363	Small membrane protein
HP432_RS21930	COG0583	DNA-binding transcription factor activity
HP432_RS21940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HP432_RS21945	COG2166	iron-sulfur cluster assembly
HP432_RS21950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HP432_RS21955	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HP432_RS21975	COG0860	N-Acetylmuramoyl-L-alanine amidase
HP432_RS21980	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HP432_RS21980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HP432_RS21985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HP432_RS21990	COG1074	ATP-dependent DNA helicase activity
HP432_RS21995	COG1025	Belongs to the peptidase M16 family
HP432_RS22000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HP432_RS22005	COG4967	type IV pilus modification protein PilV
HP432_RS22015	COG4795	General secretion pathway protein
HP432_RS22020	COG2165	general secretion pathway protein
HP432_RS22035	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HP432_RS22050	COG0861	Integral membrane protein TerC family
HP432_RS22060	COG0667	Aldo Keto reductase
HP432_RS22075	COG1609	Transcriptional regulator
HP432_RS22085	COG0583	DNA-binding transcription factor activity
HP432_RS22090	COG1794	racemase activity, acting on amino acids and derivatives
HP432_RS22095	COG2814	Major facilitator Superfamily
HP432_RS22100	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS22110	COG0183	Belongs to the thiolase family
HP432_RS22115	COG0814	amino acid
HP432_RS22135	COG4942	peptidase
HP432_RS22140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HP432_RS22145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HP432_RS22150	COG2080	2 iron, 2 sulfur cluster binding
HP432_RS22170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HP432_RS22175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HP432_RS22180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HP432_RS22195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HP432_RS22195	COG3608	succinylglutamate desuccinylase aspartoacylase
HP432_RS22200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HP432_RS22205	COG2068	MobA-Related Protein
HP432_RS22210	COG0493	'glutamate synthase
HP432_RS22210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS22215	COG0402	S-adenosylhomocysteine deaminase activity
HP432_RS22220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HP432_RS22230	COG2233	PERMEase
HP432_RS22235	COG0402	S-adenosylhomocysteine deaminase activity
HP432_RS22240	COG2252	PERMEase
HP432_RS22245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HP432_RS22255	COG2233	PERMEase
HP432_RS22275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HP432_RS22285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HP432_RS22290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HP432_RS22295	COG4974	Belongs to the 'phage' integrase family
HP432_RS22300	COG0716	FMN binding
HP432_RS22310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HP432_RS22320	COG1272	protein, Hemolysin III
HP432_RS22330	COG2723	6-phospho-beta-galactosidase activity
HP432_RS22335	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS22360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HP432_RS22365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HP432_RS22370	COG0006	proline dipeptidase activity
HP432_RS22390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HP432_RS22400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HP432_RS22420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HP432_RS22420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HP432_RS22425	COG1703	isobutyryl-CoA mutase activity
HP432_RS22430	COG1024	Enoyl-CoA hydratase
HP432_RS22435	COG0427	acetyl-CoA hydrolase
HP432_RS22440	COG0583	DNA-binding transcription factor activity
HP432_RS22445	COG2968	Membrane
HP432_RS22450	COG1279	arginine transmembrane transporter activity
HP432_RS22455	COG0668	transmembrane transport
HP432_RS22460	COG0191	fructose-bisphosphate aldolase activity
HP432_RS22475	COG1072	(Pantothenic acid kinase))
HP432_RS22480	COG3722	fumarate hydratase activity
HP432_RS22485	COG1494	fructose-1,6-bisphosphatase
HP432_RS22490	COG1063	alcohol dehydrogenase
HP432_RS22495	COG2213	PTS system mannitol-specific
HP432_RS22500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HP432_RS22505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HP432_RS22510	COG0501	Belongs to the peptidase M48B family
HP432_RS22520	COG1166	arginine decarboxylase activity
HP432_RS22540	COG2814	Major facilitator Superfamily
HP432_RS22550	COG2356	endonuclease I
HP432_RS22555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HP432_RS22560	COG0189	ligase activity
HP432_RS22575	COG2805	Type II/IV secretion system protein
HP432_RS22580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HP432_RS22585	COG0762	integral membrane protein
HP432_RS22600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HP432_RS22610	COG0252	asparaginase activity
HP432_RS22620	COG3171	Protein conserved in bacteria
HP432_RS22630	COG1194	a g-specific adenine glycosylase
HP432_RS22645	COG2211	Major facilitator Superfamily
HP432_RS22650	COG1982	Orn Lys Arg decarboxylase major
HP432_RS22655	COG1811	Na channel or pump
HP432_RS22665	COG0582	viral genome integration into host DNA
HP432_RS22670	COG2194	sulfuric ester hydrolase activity
HP432_RS22695	COG2244	polysaccharide biosynthetic process
HP432_RS22700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HP432_RS22705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HP432_RS22710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HP432_RS22715	COG0306	phosphate transporter
HP432_RS22720	COG0754	glutathionylspermidine amidase activity
HP432_RS22725	COG0625	glutathione transferase activity
HP432_RS22730	COG0298	carbon dioxide binding
HP432_RS22735	COG0375	protein maturation
HP432_RS22740	COG1773	rubredoxin
HP432_RS22745	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HP432_RS22750	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HP432_RS22755	COG5557	Pfam Polysulphide reductase, NrfD
HP432_RS22760	COG0437	4 iron, 4 sulfur cluster binding
HP432_RS22765	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HP432_RS22780	COG0667	Aldo Keto reductase
HP432_RS22790	COG1028	Short-chain dehydrogenase reductase Sdr
HP432_RS22795	COG0848	biopolymer transport protein
HP432_RS22800	COG0811	peptide transport
HP432_RS22805	COG0626	cystathionine gamma-synthase activity
HP432_RS22810	COG0586	Pfam SNARE associated Golgi protein
HP432_RS22815	COG2207	Transcriptional regulator
HP432_RS22820	COG1979	alcohol dehydrogenase
HP432_RS22825	COG0656	L-ascorbic acid biosynthetic process
HP432_RS22845	COG4238	major outer membrane lipoprotein
HP432_RS22850	COG1032	radical SAM domain protein
HP432_RS22855	COG2132	Multicopper oxidase
HP432_RS22860	COG0204	Acyl-transferase
HP432_RS22865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HP432_RS22870	COG4166	transmembrane transport
HP432_RS22875	COG2944	sequence-specific DNA binding
HP432_RS22885	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HP432_RS22890	COG3111	PFAM Bacterial OB fold (BOF) protein
HP432_RS22895	COG0745	RESPONSE REGULATOR receiver
HP432_RS22900	COG0642	Histidine kinase
HP432_RS22910	COG2249	NAD(P)H dehydrogenase (quinone) activity
HP432_RS22915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HP432_RS22920	COG0187	DNA topoisomerase II activity
HP432_RS22925	COG3150	esterase
HP432_RS22930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HP432_RS22935	COG3151	Protein conserved in bacteria
HP432_RS22940	COG0494	nUDIX hydrolase
HP432_RS22945	COG1538	Outer membrane efflux protein
HP432_RS22955	COG0754	glutathionylspermidine amidase activity
HP432_RS22960	COG3384	dioxygenase
HP432_RS22980	COG2960	long-chain fatty acid transporting porin activity
HP432_RS22985	COG3539	Fimbrial protein