locus-tag class description GZ082_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) GZ082_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GZ082_RS00025 ENOG4105VP5 Bacterial protein of unknown function (DUF937) GZ082_RS00030 ENOG410667J hydrolase GZ082_RS00035 ENOG410657R replicase EC 2.7 GZ082_RS00040 ENOG4105EMF GntR family transcriptional regulator GZ082_RS00045 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 GZ082_RS00050 ENOG4108RTU Aldolase GZ082_RS00060 ENOG4105DJB Major Facilitator Superfamily GZ082_RS00070 ENOG4105D99 atp gtp-binding protein GZ082_RS00075 ENOG4105R2A (LipO)protein GZ082_RS00095 ENOG4105FDP GntR family transcriptional regulator GZ082_RS00100 ENOG4105CI1 PTS System GZ082_RS00110 ENOG4108AHD Transcriptional regulator GZ082_RS00115 ENOG4107RUZ Sss sodium solute transporter superfamily GZ082_RS00120 ENOG4105CBG Sulfatase GZ082_RS00125 ENOG4106DRA Inner membrane protein YidI GZ082_RS00130 ENOG4105VG5 Membrane GZ082_RS00135 ENOG4105JP4 Inner membrane protein yidG GZ082_RS00140 ENOG4105J13 transcriptional regulator GZ082_RS00145 ENOG4105E5M Multidrug resistance protein D GZ082_RS00160 ENOG4105C7K acetolactate synthase GZ082_RS00165 ENOG4105M71 acetolactate synthase 1 regulatory subunit GZ082_RS00170 ENOG4108KX4 response regulator GZ082_RS00175 ENOG4105BZU Histidine kinase GZ082_RS00180 ENOG4105CXY transporter GZ082_RS00185 ENOG4105CXY transporter GZ082_RS00195 ENOG4105C7N Xanthine uracil vitamin C permease GZ082_RS00200 ENOG4108SAJ Protein of unknown function (DUF1198) GZ082_RS00210 ENOG4105T8A Uncharacterized protein YicS GZ082_RS00215 ENOG4105D01 (LipO)protein GZ082_RS00220 ENOG4108UZ3 Transporter GZ082_RS00225 ENOG4105S8Q sugar efflux transporter GZ082_RS00285 ENOG4105DFP Integrase GZ082_RS00295 ENOG4105CT4 transporter GZ082_RS00300 ENOG4105CJQ hydrolase, family 31 GZ082_RS00305 ENOG4105JV1 AsmA family GZ082_RS00310 ENOG4105C2W permease GZ082_RS00315 ENOG4105D6U Sodium Glutamate Symporter GZ082_RS00325 ENOG4105CB5 ATP-dependent DNA helicase recG GZ082_RS00330 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase GZ082_RS00335 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GZ082_RS00345 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) GZ082_RS00355 ENOG4105EN6 Membrane GZ082_RS00360 ENOG4105F5P DNA-damage-inducible protein d GZ082_RS00365 ENOG4105DSJ YicC domain protein GZ082_RS00385 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) GZ082_RS00390 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase GZ082_RS00400 ENOG4105KDC 50s ribosomal protein l28 GZ082_RS00420 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase GZ082_RS00425 ENOG4105DKP glycosyl transferase, family 9 GZ082_RS00430 ENOG4107RJ7 Glycosyl transferase (Group 1 GZ082_RS00435 ENOG4107543 (lipo)polysaccharide GZ082_RS00440 ENOG4106AH0 Glycosyl Transferase GZ082_RS00445 ENOG4105X1N Glycosyl transferase family 8 GZ082_RS00455 ENOG4105X1N Glycosyl transferase family 8 GZ082_RS00460 ENOG4105K64 Glycosyl transferase, family 2 GZ082_RS00465 ENOG41068PG O-Antigen polymerase GZ082_RS00470 ENOG4105D16 lipopolysaccharide heptosyltransferase i GZ082_RS00475 ENOG4105XA0 heptosyltransferase ii GZ082_RS00485 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GZ082_RS00495 ENOG4105K64 Glycosyl transferase, family 2 GZ082_RS00500 ENOG4105PXI polysaccharide deacetylase GZ082_RS00505 ENOG41063SB peptidase GZ082_RS00515 ENOG4107YZP Rhodanese domain protein GZ082_RS00520 ENOG4105VW4 glutaredoxin 3 GZ082_RS00535 ENOG4105D7W serine acetyltransferase GZ082_RS00540 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) GZ082_RS00550 ENOG41073TP transcriptional regulator GZ082_RS00555 ENOG4105DAA L-lactate GZ082_RS00560 ENOG4105EUR Domain-Containing protein GZ082_RS00565 ENOG4108WY4 inner membrane lipoprotein GZ082_RS00570 ENOG4108YYI Protein of unknown function (DUF2810) GZ082_RS00580 ENOG4105E61 Mannitol repressor protein GZ082_RS00590 ENOG4105CTS PTS system mannitol-specific GZ082_RS00595 ENOG4105FP6 Protein of unknown function (DUF3302) GZ082_RS00600 ENOG4105EFX secretion protein, HlyD family GZ082_RS00630 ENOG4105CNA YD repeat protein GZ082_RS00635 ENOG4108U78 Glutathione S-transferase GZ082_RS00645 ENOG4105EM7 Selenocysteine-specific translation elongation factor GZ082_RS00650 ENOG4105C0A alcohol dehydrogenase GZ082_RS00655 ENOG4105C26 Dehydrogenase GZ082_RS00665 ENOG4105KK7 inner membrane protein YiaW GZ082_RS00670 ENOG4105EFX secretion protein, HlyD family GZ082_RS00675 ENOG4108Q2M Transcriptional regulator GZ082_RS00680 ENOG4105GNX MltA-interacting MipA family protein GZ082_RS00685 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GZ082_RS00690 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase GZ082_RS00695 ENOG4105H6Q decarboxylase GZ082_RS00700 ENOG4105CMG Carbohydrate kinase GZ082_RS00705 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit GZ082_RS00710 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GZ082_RS00715 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter GZ082_RS00720 ENOG4108R66 Conserved Protein GZ082_RS00730 ENOG4105J4Q Transcriptional regulator GZ082_RS00735 ENOG4108XIB electron transport protein ysaA GZ082_RS00740 ENOG4105JKW Valine--pyruvate aminotransferase GZ082_RS00745 ENOG4107T9C Alpha amylase catalytic region GZ082_RS00750 ENOG4108UR8 BAX protein GZ082_RS00755 ENOG4105T16 Transcriptional regulator (AraC family) GZ082_RS00760 ENOG4108HWW ABC transporter GZ082_RS00765 ENOG4105C2J ABC transporter GZ082_RS00770 ENOG4105DFW ABC transporter GZ082_RS00780 ENOG4105CMG Carbohydrate kinase GZ082_RS00785 ENOG410688U Inner membrane protein yiaB GZ082_RS00790 ENOG4108Z12 YiaAB two helix domain-containing protein GZ082_RS00795 ENOG4105MEV Acyl-transferase GZ082_RS00815 ENOG41060TC Hok gef cell toxic protein GZ082_RS00825 ENOG4105MVF Transcriptional regulator GZ082_RS00830 ENOG4106JH6 (LipO)protein GZ082_RS00840 ENOG4108ZG0 Ompa motb domain protein GZ082_RS00845 ENOG4107QY8 reductase GZ082_RS00850 ENOG4105HNP -acetyltransferase GZ082_RS00855 ENOG4108R3E Dna-3-methyladenine glycosylase i GZ082_RS00860 ENOG4105EAX Putative lipase GZ082_RS00865 ENOG4105FCD Major Facilitator GZ082_RS00870 ENOG4105DIJ Phosphoethanolamine transferase GZ082_RS00890 ENOG4105DEF Extracellular solute-binding protein, family 5 GZ082_RS00895 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GZ082_RS00900 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GZ082_RS00905 ENOG4105C3U ABC transporter GZ082_RS00910 ENOG4108JQ7 (ABC) transporter GZ082_RS00915 ENOG4105C44 Serine transporter GZ082_RS00935 ENOG4105WQA Cellulose biosynthesis protein BcsF GZ082_RS00940 ENOG4105U74 cellulose biosynthesis protein BcsE GZ082_RS00945 ENOG410661M cytoplasmic protein GZ082_RS00955 ENOG4107QZ7 Cellulose synthase catalytic subunit GZ082_RS00960 ENOG4107EEX Cellulose synthase regulator protein GZ082_RS00965 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) GZ082_RS00970 ENOG4105EJG cellulose synthase GZ082_RS00975 ENOG4105BZU Histidine kinase GZ082_RS00985 ENOG4105CS0 peptidase GZ082_RS00995 ENOG4105CMB EAL domain-containing protein GZ082_RS01000 ENOG41066T0 asmA family GZ082_RS01005 ENOG4105CSH Transporter GZ082_RS01010 ENOG4107H3J ribonuclease GZ082_RS01015 ENOG4105CBN LysR family transcriptional regulator GZ082_RS01020 ENOG4106S2D Transcriptional regulator GZ082_RS01030 ENOG4105CA0 peroxidase GZ082_RS01035 ENOG4105CVK Glutamate decarboxylase GZ082_RS01040 ENOG4108NKV transcriptional regulator GZ082_RS01050 ENOG4105BZS acriflavin resistance protein GZ082_RS01055 ENOG4105C1P efflux transporter, rnd family, mfp subunit GZ082_RS01065 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci GZ082_RS01070 ENOG4108YK4 Acid-resistance membrane protein GZ082_RS01075 ENOG41060V2 Acid-resistance protein GZ082_RS01080 ENOG4105XXV Acid-resistance protein GZ082_RS01085 ENOG4105KT7 mgtC SapB transporter GZ082_RS01095 ENOG4105Y4Z Outer Membrane Lipoprotein GZ082_RS01120 ENOG4105K89 arsenate reductase GZ082_RS01125 ENOG4107R5R arsenical pump membrane protein GZ082_RS01130 ENOG4105KBH arsR family transcriptional regulator GZ082_RS01145 ENOG4105DC8 reductase GZ082_RS01150 ENOG4105D6S protein involved in catabolism of external DNA GZ082_RS01155 ENOG4105DGW oligopeptidase A GZ082_RS01165 ENOG4105DUX Transporter GZ082_RS01180 ENOG4105CJ3 phosphate transporter GZ082_RS01185 ENOG4105CBX hi0933 family GZ082_RS01190 ENOG4107UNS conserved inner membrane protein GZ082_RS01205 ENOG4105D0S secretion protein (HlyD GZ082_RS01210 ENOG4105CJ1 ABC, transporter GZ082_RS01215 ENOG4105CMI transporter GZ082_RS01230 ENOG4105D2N Aldolase GZ082_RS01245 ENOG4105DT3 PTS system, galactitol-specific IIc component GZ082_RS01250 ENOG41090UW PTS System GZ082_RS01275 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) GZ082_RS01280 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GZ082_RS01285 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GZ082_RS01290 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein GZ082_RS01295 ENOG4107YAK holo-(acyl carrier protein) synthase 2 GZ082_RS01300 ENOG4105DSF transport protein GZ082_RS01305 ENOG4105F9N Major Facilitator Superfamily GZ082_RS01310 ENOG4108W1V Lipoprotein GZ082_RS01315 ENOG4105EX9 Membrane GZ082_RS01330 ENOG4107FS9 Membrane GZ082_RS01340 ENOG4105MG3 Membrane GZ082_RS01345 ENOG4106H78 methyltransferase GZ082_RS01350 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) GZ082_RS01355 ENOG4105CAK Cell division ATP-binding protein ftsE GZ082_RS01360 ENOG4105CRP Part of the ABC transporter FtsEX involved in GZ082_RS01365 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GZ082_RS01370 ENOG4105CP9 extracellular ligand-binding receptor GZ082_RS01385 ENOG4105U59 -acetyltransferase GZ082_RS01390 ENOG4105CP9 extracellular ligand-binding receptor GZ082_RS01395 ENOG4105C32 Amino acid ABC transporter (Permease) GZ082_RS01400 ENOG4105CF8 branched-chain amino acid ABC transporter, permease GZ082_RS01405 ENOG4105C0Z ABC transporter GZ082_RS01410 ENOG4108IV0 ABC, transporter GZ082_RS01415 ENOG4105BZ7 extracellular solute-binding protein family 1 GZ082_RS01420 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component GZ082_RS01425 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component GZ082_RS01435 ENOG4107T6V glycerophosphoryl diester phosphodiesterase GZ082_RS01440 ENOG4105WC8 Conserved Protein GZ082_RS01445 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) GZ082_RS01450 ENOG4106FA4 GZ082_RS01465 ENOG4105GMB type VI secretion system effector, hcp1 family GZ082_RS01470 ENOG4105WCN acetyltransferase GZ082_RS01475 ENOG4105D9R oxidoreductase GZ082_RS01480 ENOG4105C2I pirin domain protein GZ082_RS01485 ENOG4105DIQ Transcriptional regulator GZ082_RS01490 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family GZ082_RS01495 ENOG4105C6Z Gluconate GZ082_RS01500 ENOG41076UM multiple antibiotic resistance (MarC)-related protein GZ082_RS01505 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GZ082_RS01515 ENOG4108IUM Glycogen debranching enzyme GZ082_RS01530 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GZ082_RS01555 ENOG4105C6V Glycerol-3-phosphate dehydrogenase GZ082_RS01570 ENOG4105E98 transcriptional regulator DeoR family GZ082_RS01575 ENOG4105CYB regulatoR GZ082_RS01580 ENOG4105E0Y RtcB Protein GZ082_RS01595 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) GZ082_RS01600 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) GZ082_RS01605 ENOG4105C6Z Gluconate GZ082_RS01615 ENOG4105MJ2 Competence protein GZ082_RS01625 ENOG4105DNE Transposase GZ082_RS01635 ENOG4105CE1 Ferrous iron transport protein b GZ082_RS01640 ENOG4105XFK Ferrous iron transport protein A GZ082_RS01645 ENOG4105BZM domain protein GZ082_RS01650 ENOG4108RRZ Transcription elongation factor GreB GZ082_RS01660 ENOG4105E0F Histidine kinase GZ082_RS01670 ENOG4108MAJ Membrane GZ082_RS01680 ENOG4105VEJ Heat shock protein GZ082_RS01685 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 GZ082_RS01690 ENOG4105DQY intracellular growth attenuator GZ082_RS01695 ENOG4107RK2 ADP-ribose diphosphatase NudE GZ082_RS01700 ENOG4108JQC penicillin-binding protein 1A GZ082_RS01705 ENOG4108U1Q Pilus assembly protein GZ082_RS01710 ENOG41065NF Fimbrial assembly family protein GZ082_RS01715 ENOG4105XPX DNA utilization protein HofO GZ082_RS01720 ENOG4105ITY Required for the use of extracellular DNA as a nutrient GZ082_RS01725 ENOG4105E4G Type IV pilus GZ082_RS01740 ENOG4105EGB membrane protein DamX GZ082_RS01745 ENOG4105DFE Dna adenine methylase GZ082_RS01750 ENOG4105DJV ribulose-phosphate 3-epimerase GZ082_RS01755 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) GZ082_RS01760 ENOG4105C31 Tryptophanyl-tRNA synthetase GZ082_RS01765 ENOG4108M21 GZ082_RS01770 ENOG4105RMW regulation of transcription, DNA-dependent GZ082_RS01775 ENOG4108626 Racemase GZ082_RS01780 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) GZ082_RS01785 ENOG41080QX K07048 phosphotriesterase-related protein GZ082_RS01790 ENOG4105MUZ Protein of unknown function DUF2620 GZ082_RS01795 ENOG4106M0N transport system permease protein GZ082_RS01800 ENOG4106PKC pyridoxal phosphate binding GZ082_RS01805 ENOG4105VYH GZ082_RS01815 ENOG4107V9H nitrite transporter GZ082_RS01820 ENOG4105WZK nitrite reductase NADPH small subunit GZ082_RS01825 ENOG4107QZF nitrite reductase NADPH large subunit GZ082_RS01835 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GZ082_RS01845 ENOG4105MZU cell filamentation protein GZ082_RS01850 ENOG4105DDQ anthranilate synthase GZ082_RS01855 ENOG4105C8Y Acetylornithine aminotransferase GZ082_RS01860 ENOG410613R integral membrane protein, YccS YhfK family GZ082_RS01870 ENOG4108UKZ OsmC family GZ082_RS01875 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) GZ082_RS01885 ENOG4105DNZ Alpha Beta Hydrolase GZ082_RS01890 ENOG4105C5H ABC transporter GZ082_RS01905 ENOG4105VKU nucleicacid-binding protein GZ082_RS01910 ENOG4108YZY peptidylprolyl cis-trans isomerase GZ082_RS01920 ENOG4108V1T peptidylprolyl cis-trans isomerase GZ082_RS01925 ENOG4105WWK YheO domain protein GZ082_RS01965 ENOG4105W53 bacterioferritin-associated ferredoxin GZ082_RS01970 ENOG4108UQY Iron-storage protein GZ082_RS01995 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) GZ082_RS02040 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) GZ082_RS02085 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) GZ082_RS02090 ENOG41067V7 50S ribosomal protein L36 GZ082_RS02120 ENOG4105VTS DnaJ-like, subfamily C GZ082_RS02125 ENOG4105W1Y Transcriptional regulator GZ082_RS02130 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system GZ082_RS02140 ENOG4105C1A potassium transporter peripheral membrane GZ082_RS02160 ENOG4105C79 DNA protecting protein DprA GZ082_RS02170 ENOG4108WI1 Dna topoisomerase GZ082_RS02185 ENOG4105SG3 Protein of unknown function (DUF1488) GZ082_RS02190 ENOG4108Z0R Transferase GZ082_RS02230 ENOG4105CDA abc transporter atp-binding protein GZ082_RS02235 ENOG4105DRP amino acid AbC transporter GZ082_RS02240 ENOG4105EZ7 amino acid ABC transporter GZ082_RS02260 ENOG4105XCM membrane LIPOPROTEIN GZ082_RS02265 ENOG4105BZS acriflavin resistance protein GZ082_RS02270 ENOG4105C1P efflux transporter, rnd family, mfp subunit GZ082_RS02275 ENOG4108XG4 DNA-binding transcriptional regulator GZ082_RS02280 ENOG41061ME transport protein GZ082_RS02285 ENOG4105CEC DNA methylase N-4 N-6 GZ082_RS02295 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GZ082_RS02305 ENOG4108IA2 Sodium pantothenate symporter GZ082_RS02310 ENOG4105RG0 Membrane GZ082_RS02315 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase GZ082_RS02320 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein GZ082_RS02325 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family GZ082_RS02330 ENOG41062P1 Diguanylate cyclase phosphodiesterase GZ082_RS02340 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) GZ082_RS02345 ENOG4105VQ7 Rod shape-determining protein MreD GZ082_RS02355 ENOG4105C03 ribonuclease GZ082_RS02360 ENOG4105QD6 exported protein GZ082_RS02365 ENOG4105D1U peptidase U62 modulator of DNA gyrase GZ082_RS02370 ENOG4105CR8 Transcriptional regulator GZ082_RS02375 ENOG4105ZQC membrane protein AaeX GZ082_RS02390 ENOG4105UNR (Barnase) inhibitor GZ082_RS02395 ENOG4105RID UPF0379 protein yhcN GZ082_RS02410 ENOG4105C0H protease GZ082_RS02415 ENOG4105C0H protease GZ082_RS02420 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III GZ082_RS02425 ENOG4105D6Z AFG1 family ATPase GZ082_RS02440 ENOG4107MKT Stringent starvation protein a GZ082_RS02445 ENOG4105KB2 stringent starvation protein b GZ082_RS02450 ENOG4105CEE C4-dicarboxylate transporter GZ082_RS02455 ENOG4108QBF Transcriptional regulator GZ082_RS02465 ENOG4105JHE Major Facilitator Superfamily GZ082_RS02480 ENOG4108R66 Conserved Protein GZ082_RS02485 ENOG4105DFS Conserved Protein GZ082_RS02490 ENOG4105BZ8 glutamate synthase GZ082_RS02495 ENOG4105CBC glutamate synthase GZ082_RS02500 ENOG4105N5T Radical SAM Protein GZ082_RS02505 ENOG4105BZU Histidine kinase GZ082_RS02510 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain GZ082_RS02520 ENOG4108NIH transferase activity, transferring phosphorus-containing groups GZ082_RS02525 ENOG41080Z8 PHOSPHOCARRIER protein GZ082_RS02535 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN GZ082_RS02540 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA GZ082_RS02545 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GZ082_RS02550 ENOG4108IUZ ABC transporter GZ082_RS02555 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA GZ082_RS02560 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) GZ082_RS02565 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase GZ082_RS02570 ENOG4105C2X Arabinose 5-phosphate isomerase GZ082_RS02575 ENOG4105FEU K -dependent Na -Ca exchanger GZ082_RS02580 ENOG4105DHJ ABC, transporter GZ082_RS02585 ENOG4105CY3 ABC transporter, permease GZ082_RS02590 ENOG4107PE3 Mammalian cell entry related domain protein GZ082_RS02595 ENOG4105E3I toluene tolerance GZ082_RS02600 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane GZ082_RS02605 ENOG4105VFK BolA family GZ082_RS02615 ENOG4105HVQ Regulatory factor of maltose metabolism GZ082_RS02620 ENOG4105EAH synthase GZ082_RS02635 ENOG4105QYV Membrane GZ082_RS02645 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase GZ082_RS02650 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) GZ082_RS02655 ENOG4105HBR Rna-binding protein GZ082_RS02665 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GZ082_RS02670 ENOG4105EEI dihydropteroate synthase GZ082_RS02680 ENOG4105NTZ Preprotein translocase subunit SecG GZ082_RS02690 ENOG4105DIJ Phosphoethanolamine transferase GZ082_RS02710 ENOG4105CHV Transcription elongation factor NusA GZ082_RS02750 ENOG4105C1J atp-dependent rna helicase GZ082_RS02755 ENOG4105CIC tryptophan-specific transport protein GZ082_RS02765 ENOG4105DEN Luciferase family GZ082_RS02785 ENOG4108YYD acetyltransferase GZ082_RS02800 ENOG4107R7Y intracellular protease Pfpi family GZ082_RS02805 ENOG4105K4T epimerase GZ082_RS02810 ENOG4107S21 permease GZ082_RS02815 ENOG4105W4M Transport-associated protein GZ082_RS02835 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) GZ082_RS02855 ENOG4105CW0 outer membrane usher protein GZ082_RS02860 ENOG4108VCD Chaperone GZ082_RS02865 ENOG4105Q10 Fimbrial-like protein GZ082_RS02870 ENOG4106HBN Galactosamine-6-phosphate isomerase GZ082_RS02875 ENOG4105F3R pts system mannose fructose sorbose family iid GZ082_RS02880 ENOG4105ETZ PTS System GZ082_RS02885 ENOG4108UZY PTS System GZ082_RS02895 ENOG4105E70 isomerase GZ082_RS02900 ENOG4105CE4 GlcNAc 6-P deacetylase GZ082_RS02905 ENOG4108YTN IIa component GZ082_RS02910 ENOG4105F3R pts system mannose fructose sorbose family iid GZ082_RS02920 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB GZ082_RS02930 ENOG4105E98 transcriptional regulator DeoR family GZ082_RS02935 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression GZ082_RS02940 ENOG4105ZEG Suppressor protein GZ082_RS02945 ENOG4105CTX dehydratase GZ082_RS02950 ENOG4105DJB Major Facilitator Superfamily GZ082_RS02960 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GZ082_RS02965 ENOG4105BZW Glycerate kinase GZ082_RS02995 ENOG410811B TRANSCRIPTIONal GZ082_RS03010 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GZ082_RS03015 ENOG4105C6N Formate acetyltransferase GZ082_RS03020 ENOG4105KME endoribonuclease L-psp GZ082_RS03025 ENOG4105EJQ L-serine dehydratase GZ082_RS03030 ENOG4105C44 Serine transporter GZ082_RS03040 ENOG4106D80 Uncharacterized protein YhaL GZ082_RS03045 ENOG4108CNN domain protein GZ082_RS03050 ENOG4105CWB LysR family transcriptional Regulator GZ082_RS03055 ENOG4105KAF membrAne GZ082_RS03060 ENOG4105KAF membrAne GZ082_RS03065 ENOG4105CHF Glutathione S-transferase GZ082_RS03070 ENOG4108VBZ doxx family GZ082_RS03075 ENOG4105YJD GZ082_RS03080 ENOG41090KG Inner membrane protein YqjE GZ082_RS03085 ENOG4105NE1 Conserved Protein GZ082_RS03090 ENOG4105WAY exported protein GZ082_RS03095 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) GZ082_RS03100 ENOG4106W5V Membrane GZ082_RS03105 ENOG4107YCY Transcriptional regulator GZ082_RS03130 ENOG4105DPW Major facilitator superfamily MFS_1 GZ082_RS03140 ENOG4105CTX dehydratase GZ082_RS03145 ENOG4105P66 Membrane GZ082_RS03150 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) GZ082_RS03160 ENOG4105DU1 integral membrane protein, terc GZ082_RS03165 ENOG4105EE0 oxidoreductase GZ082_RS03170 ENOG4108UB4 uncharacterized protein ygjQ GZ082_RS03175 ENOG4108VKG metal-dependent hydrolase GZ082_RS03190 ENOG4108Z3N Transcriptional regulator GZ082_RS03195 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GZ082_RS03200 ENOG4107WCA isomerase GZ082_RS03205 ENOG4107W6W Conserved Protein GZ082_RS03210 ENOG4105E5D amino acid GZ082_RS03215 ENOG4105FK9 beta-D-galactosidase beta subunit GZ082_RS03220 ENOG4105CNT hydrolase family 2 GZ082_RS03225 ENOG4105CQ4 Transcriptional regulator GZ082_RS03230 ENOG4108Y51 tRNA-binding protein GZ082_RS03240 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor GZ082_RS03245 ENOG4105NTW Transcriptional regulator GZ082_RS03250 ENOG4105Q26 Siderophore-interacting protein GZ082_RS03265 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GZ082_RS03270 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) GZ082_RS03285 ENOG4107QPK )-transporter GZ082_RS03290 ENOG4107GFK fumarate GZ082_RS03295 ENOG4106DSS Tartrate dehydratase subunit alpha GZ082_RS03300 ENOG4105EJC lysr family transcriptional regulator GZ082_RS03310 ENOG4107ZVW dihydroneopterin aldolase GZ082_RS03325 ENOG4106MWK domain protein GZ082_RS03330 ENOG4105I7R Adenylate cyclase GZ082_RS03355 ENOG4107S78 Band 7 protein GZ082_RS03360 ENOG4105PV3 Inner membrane protein yqiJ GZ082_RS03370 ENOG4108MY7 Fimbrial GZ082_RS03375 ENOG4108TTM chaperone GZ082_RS03385 ENOG4105H8W Fimbrial protein GZ082_RS03390 ENOG4105W0Z cytoplasmic protein GZ082_RS03410 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b GZ082_RS03415 ENOG4106032 Glutathionylspermidine synthase GZ082_RS03425 ENOG4105DFG type I secretion outer membrane protein GZ082_RS03430 ENOG41087AY ADP-Ribose pyrophosphatase GZ082_RS03435 ENOG4108SX3 cytoplasmic protein GZ082_RS03440 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) GZ082_RS03445 ENOG4105IPS esterase GZ082_RS03450 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GZ082_RS03455 ENOG4105VRH Antibiotic biosynthesis monooxygenase GZ082_RS03460 ENOG4105NF4 modulator of drug activity GZ082_RS03465 ENOG4107DEU Inner membrane protein YgiZ GZ082_RS03470 ENOG4105DHQ Histidine kinase GZ082_RS03475 ENOG4105XJC Two component transcriptional regulator (Winged helix family GZ082_RS03480 ENOG4105H4F exported protein GZ082_RS03485 ENOG4105F4I Transcriptional regulator GZ082_RS03490 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GZ082_RS03495 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase GZ082_RS03500 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) GZ082_RS03505 ENOG4105CCT upf0313 protein GZ082_RS03515 ENOG4105ZKC Conserved Protein GZ082_RS03520 ENOG4105CV8 reductase GZ082_RS03525 ENOG4108I6A alcohol dehydrogenase GZ082_RS03530 ENOG4105CF7 AraC family transcriptional regulator GZ082_RS03535 ENOG4108K81 inner membrane protein YghB GZ082_RS03540 ENOG4105C28 cystathionine GZ082_RS03545 ENOG4105CWK Biopolymer transport protein, ExbB GZ082_RS03550 ENOG4108ZZF transport protein (ExbD) GZ082_RS03555 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GZ082_RS03565 ENOG4105CPC Aldo Keto reductase GZ082_RS03575 ENOG410900S Protein of unknown function (DUF2623) GZ082_RS03580 ENOG4105E3S small subunit GZ082_RS03585 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GZ082_RS03590 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit GZ082_RS03595 ENOG4105DPX Hydrogenase, large subunit GZ082_RS03600 ENOG4108USZ hydrogenase GZ082_RS03605 ENOG4108WGS hydrogenase 2-specific chaperone GZ082_RS03615 ENOG41082MF Hydrogenase assembly chaperone hypC hupF GZ082_RS03620 ENOG4105CYM Glutathione S-transferase GZ082_RS03625 ENOG4106032 Glutathionylspermidine synthase GZ082_RS03630 ENOG4105CJ3 phosphate transporter GZ082_RS03635 ENOG4108GH0 ATP-binding protein yghT GZ082_RS03640 ENOG4108NDC ATP-binding protein yghS GZ082_RS03645 ENOG4106FPV ATP-binding protein YghR GZ082_RS03650 ENOG4108S55 polysaccharide biosynthesis protein GZ082_RS03660 ENOG4108UUE Transcriptional regulator GZ082_RS03665 ENOG4108M8S permease YjgP YjgQ family protein GZ082_RS03675 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GZ082_RS03680 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GZ082_RS03690 ENOG4107RCI amp-dependent synthetase and ligase GZ082_RS03700 ENOG4108KWP DNA-binding transcriptional regulator GlcC GZ082_RS03705 ENOG4105CQB FAD linked oxidase domain protein GZ082_RS03710 ENOG4105EU8 FAD linked oxidase domain protein GZ082_RS03715 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GZ082_RS03720 ENOG4108ZJF Glcg protein GZ082_RS03725 ENOG4107QP3 malate synthase g GZ082_RS03730 ENOG4105DAA L-lactate GZ082_RS03745 ENOG410765S (LipO)protein GZ082_RS03760 ENOG4107QHF type ii secretion system protein e GZ082_RS03765 ENOG4105D7Q type ii secretion system GZ082_RS03770 ENOG4108VAU general secretion pathway protein G GZ082_RS03780 ENOG4105X5Z General secretion pathway protein I GZ082_RS03800 ENOG4105U1E general secretion pathway protein M GZ082_RS03805 ENOG41090SZ ABC-2 type transporter GZ082_RS03835 ENOG41084CK capsule polysaccharide GZ082_RS03840 ENOG4105E12 capsule polysaccharide GZ082_RS03845 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) GZ082_RS03850 ENOG4107V1M polysaccharide export protein GZ082_RS03855 ENOG4105ECX polysaccharide export GZ082_RS03860 ENOG4105C2X Arabinose 5-phosphate isomerase GZ082_RS03875 ENOG4105X54 addiction module antidote protein GZ082_RS03900 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles GZ082_RS03910 ENOG4108YGG dna repair protein GZ082_RS03915 ENOG4106549 Antirestriction protein GZ082_RS03920 ENOG4106H6R UPF0380 protein GZ082_RS03935 ENOG4105TS0 gtp-binding protein GZ082_RS04025 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) GZ082_RS04055 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein GZ082_RS04090 ENOG4107SCJ type I restriction enzyme EcoKI subunit R GZ082_RS04105 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) GZ082_RS04120 ENOG4105T40 surface antigen msp4 family protein GZ082_RS04150 ENOG4105DIJ Phosphoethanolamine transferase GZ082_RS04195 ENOG4105DFP Integrase GZ082_RS04205 ENOG4108UQV Membrane GZ082_RS04210 ENOG4105CXN decarboxylase GZ082_RS04215 ENOG4105EAA nucleoside GZ082_RS04230 ENOG4105CEN a g-specific adenine glycosylase GZ082_RS04240 ENOG41090ED Protein with unknown function (DUF469) GZ082_RS04245 ENOG4105K33 Periplasmic Protein GZ082_RS04250 ENOG4105HDK L-asparaginase GZ082_RS04255 ENOG4106MH3 alpha helix chain GZ082_RS04260 ENOG4105CSA Coproporphyrinogen iii oxidase GZ082_RS04265 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) GZ082_RS04275 ENOG4108VIA integral membrane protein GZ082_RS04280 ENOG4105DFA alanine racemase domain protein GZ082_RS04285 ENOG4105CZX twitching motility protein GZ082_RS04305 ENOG4105D7Z glutathione synthase GZ082_RS04310 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) GZ082_RS04315 ENOG4105RWS endonuclease I GZ082_RS04325 ENOG4107QNK )-transporter GZ082_RS04345 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) GZ082_RS04360 ENOG4108K0D peptidase, M48 GZ082_RS04365 ENOG4105CV1 Transketolase (EC 2.2.1.1) GZ082_RS04375 ENOG4105EPW hflc protein GZ082_RS04380 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia GZ082_RS04385 ENOG4105CTS PTS system mannitol-specific GZ082_RS04390 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein GZ082_RS04400 ENOG4108R4K DNA-binding, transcriptional regulator GZ082_RS04405 ENOG4107Z1W Fructose transport system kinase GZ082_RS04410 ENOG4108JJB ABC transporter GZ082_RS04415 ENOG4108JJB ABC transporter GZ082_RS04445 ENOG4105D2N Aldolase GZ082_RS04450 ENOG4105D64 Mechanosensitive ion channel GZ082_RS04455 ENOG4108ZUB Lysine exporter protein (Lyse ygga) GZ082_RS04460 ENOG4105MPN Membrane GZ082_RS04465 ENOG4105DEQ transcriptional regulator GZ082_RS04470 ENOG4105D5P Methylmalonyl-coA mutase GZ082_RS04490 ENOG4108JQ1 Dehydrogenase GZ082_RS04500 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase GZ082_RS04520 ENOG4107RAQ aminopeptidase GZ082_RS04525 ENOG4105D0A hydroxylase GZ082_RS04530 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GZ082_RS04555 ENOG4105CS2 ec 3.2.1.21 GZ082_RS04565 ENOG4108UT2 hemolysin iii GZ082_RS04570 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) GZ082_RS04575 ENOG4105Y75 tpr repeat protein GZ082_RS04580 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB GZ082_RS04585 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) GZ082_RS04590 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GZ082_RS04595 ENOG4105T95 Thiol disulfide interChange protein GZ082_RS04600 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) GZ082_RS04610 ENOG4105CRK lysyL-tRNA synthetase GZ082_RS04630 ENOG4105C2W permease GZ082_RS04635 ENOG4105BZ8 glutamate synthase GZ082_RS04640 ENOG4108R8B oxidoreductase Fe-S subunit GZ082_RS04645 ENOG4105C7N Xanthine uracil vitamin C permease GZ082_RS04650 ENOG4107QUY Guanine deaminase GZ082_RS04655 ENOG4105C2W permease GZ082_RS04660 ENOG4105C7W Xanthine dehydrogenase GZ082_RS04665 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase GZ082_RS04670 ENOG4107UUR Chlorohydrolase aminohydrolase GZ082_RS04675 ENOG4105BZ8 glutamate synthase GZ082_RS04680 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase GZ082_RS04685 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC GZ082_RS04690 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family GZ082_RS04695 ENOG4105C5B carbamate kinase GZ082_RS04705 ENOG4107S4Y M20 DapE family protein YgeY GZ082_RS04710 ENOG4107RCH Diaminopropionate ammonia-lyase GZ082_RS04715 ENOG4105IW6 Carbamoyltransferase GZ082_RS04720 ENOG4108JUB Transcriptional regulator GZ082_RS04725 ENOG4108UTP (2Fe-2S)-binding domain protein GZ082_RS04730 ENOG4108HR6 Dehydrogenase GZ082_RS04735 ENOG4105C7W Xanthine dehydrogenase GZ082_RS04740 ENOG4108K5P (LipO)protein GZ082_RS04760 ENOG4105ISV protein with bipartite regulator domain GZ082_RS04770 ENOG4108MHD transport protein GZ082_RS04775 ENOG4105CHU acetyl-coa acetyltransferase GZ082_RS04785 ENOG4105CHR reductase GZ082_RS04790 ENOG4107QNK )-transporter GZ082_RS04800 ENOG4105RQF LysR family Transcriptional regulator GZ082_RS04810 ENOG41060NJ transcriptional regulator GZ082_RS04825 ENOG4105CPC Aldo Keto reductase GZ082_RS04830 ENOG4105SUV lipoprotein YgdR GZ082_RS04835 ENOG4105EE5 Membrane protein terC GZ082_RS04850 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase GZ082_RS04865 ENOG4105IPU prepilin peptidase dependent protein A GZ082_RS04870 ENOG4105JCS prepilin peptidase dependent protein GZ082_RS04875 ENOG4105SEN Protein of unknown function (DUF2509) GZ082_RS04880 ENOG4105RVB Prepilin peptidase dependent protein c GZ082_RS04885 ENOG4105DSY exodeoxyribonuclease V, gamma GZ082_RS04890 ENOG4107QXK peptidase GZ082_RS04895 ENOG4107QKA exodeoxyribonuclease V beta GZ082_RS04900 ENOG4107QYX exodeoxyribonuclease v alpha GZ082_RS04905 ENOG4108EKC n-acetylglutamate synthase GZ082_RS04910 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GZ082_RS04960 ENOG4105CA3 membrane-bound lytic murein transglycosylase GZ082_RS04965 ENOG4105CUZ uba thif-type nad fad binding protein GZ082_RS04970 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) GZ082_RS04975 ENOG4105C9B Cysteine desulfurase GZ082_RS04980 ENOG4105M5B (LipO)protein GZ082_RS04985 ENOG4105ETT transcriptional Regulator, LysR family GZ082_RS04990 ENOG4105M08 Membrane GZ082_RS05000 ENOG4107EDW L-fucose operon activator GZ082_RS05010 ENOG4105CMG Carbohydrate kinase GZ082_RS05020 ENOG4105EDR glucose galactose transporter GZ082_RS05025 ENOG4107W7X Aldolase GZ082_RS05030 ENOG4105C0A alcohol dehydrogenase GZ082_RS05040 ENOG4105EJQ L-serine dehydratase GZ082_RS05045 ENOG4105C44 Serine transporter GZ082_RS05050 ENOG4105EWT decarboxylase family GZ082_RS05065 ENOG4105WP7 tRNA pseudouridine synthase C GZ082_RS05070 ENOG4105DR9 pseudouridine synthase GZ082_RS05075 ENOG4105QDK Flavodoxin GZ082_RS05080 ENOG4105DJB Major Facilitator Superfamily GZ082_RS05085 ENOG4105EQX glucarate dehydratase GZ082_RS05090 ENOG4105EQX glucarate dehydratase GZ082_RS05095 ENOG4105BZU Histidine kinase GZ082_RS05100 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) GZ082_RS05105 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) GZ082_RS05110 ENOG4106A2Z transcriptional regulator antitoxin, MazE GZ082_RS05115 ENOG4105MZG transcriptional modulator of maze toxin, mazf GZ082_RS05120 ENOG4105DXN mazG family GZ082_RS05135 ENOG4105VNT transposase (IS4 family) protein GZ082_RS05140 ENOG4105HA9 of methanol dehydrogenase type GZ082_RS05150 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) GZ082_RS05155 ENOG4108CWB sugar kinase ygcE GZ082_RS05160 ENOG4108ITV Inner membrane protein yqcE GZ082_RS05165 ENOG4105CHR reductase GZ082_RS05170 ENOG4107R3A FAD linked oxidase domain protein GZ082_RS05175 ENOG4105C54 Major Facilitator superfamily GZ082_RS05180 ENOG4106IKH Electron transfer flavoprotein GZ082_RS05185 ENOG4105YBM electron transfer flavoprotein subunit ygcQ GZ082_RS05190 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator GZ082_RS05195 ENOG4105WQV ferredoxin-like protein GZ082_RS05200 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GZ082_RS05205 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase GZ082_RS05225 ENOG4107635 Hok Gef family protein GZ082_RS05230 ENOG4105DTT CRISPR-associated helicase, cas3 GZ082_RS05245 ENOG41060M0 Crispr-associated protein, cse4 family GZ082_RS05250 ENOG4108VWQ crispr-associated protein GZ082_RS05260 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) GZ082_RS05270 ENOG4108MXK alkaline phosphatase isozyme conversion GZ082_RS05290 ENOG4105N0Z inner membrane protein ygbE GZ082_RS05325 ENOG4108K5P (LipO)protein GZ082_RS05330 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GZ082_RS05340 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GZ082_RS05345 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) GZ082_RS05350 ENOG4105KZM cytoplasmic protein GZ082_RS05355 ENOG4105C6Z Gluconate GZ082_RS05360 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GZ082_RS05365 ENOG4105FB2 class II Aldolase GZ082_RS05370 ENOG4105G63 Type III effector Hrp-dependent GZ082_RS05375 ENOG4105ZXK Dehydrogenase GZ082_RS05380 ENOG4105MVE transcriptional regulator GZ082_RS05385 ENOG4105MEW serine threonine protein phosphatase GZ082_RS05400 ENOG4105VXR cytoplasmic protein GZ082_RS05405 ENOG4108JUA Transcriptional regulator GZ082_RS05410 ENOG4105C45 hydrogenase expression formation protein (HypE) GZ082_RS05415 ENOG4105CQS hydrogenase expression formation protein HypD GZ082_RS05420 ENOG41083WG hydrogenase assembly chaperone GZ082_RS05425 ENOG4107RSS Hydrogenase accessory protein HypB GZ082_RS05430 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GZ082_RS05435 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA GZ082_RS05440 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) GZ082_RS05445 ENOG4107R30 NADH dehydrogenase GZ082_RS05450 ENOG4107TDF Formate hydrogenlyase subunit 4 GZ082_RS05455 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GZ082_RS05460 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit GZ082_RS05465 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit GZ082_RS05470 ENOG4105I6X formate hydrogenlyase maturation GZ082_RS05475 ENOG4108MG9 hydrogenase 3 maturation protease GZ082_RS05485 ENOG4108Z3N Transcriptional regulator GZ082_RS05495 ENOG4105CS2 ec 3.2.1.21 GZ082_RS05500 ENOG4105C5Y PTS System GZ082_RS05505 ENOG4105DDV Transcriptional regulator (LacI family GZ082_RS05510 ENOG4108RC0 Electron transport protein GZ082_RS05515 ENOG4105C8H hydrogenase maturation protein Hypf GZ082_RS05540 ENOG410804X Transcriptional regulator GZ082_RS05545 ENOG4105J92 DNA-binding transcriptional activator GutM GZ082_RS05550 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase GZ082_RS05555 ENOG4105VI0 Pts system, glucitol sorbitol-specific GZ082_RS05560 ENOG4105DZY Pts system, glucitol sorbitol-specific GZ082_RS05565 ENOG410787A Pts system, glucitol sorbitol-specific GZ082_RS05570 ENOG4105CVE Lytic murein transglycosylase GZ082_RS05575 ENOG4107TH8 cina domain protein GZ082_RS05595 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) GZ082_RS05625 ENOG4107VXZ Hydrolase GZ082_RS05630 ENOG4105W39 Membrane GZ082_RS05645 ENOG4105C0R drug resistance transporter emrb qaca subfamily GZ082_RS05650 ENOG4105CW7 secretion protein, HlyD family GZ082_RS05655 ENOG4105NTK Transcriptional repressor Mpra GZ082_RS05660 ENOG4105ZED uncharacterized protein ygaH GZ082_RS05665 ENOG4108UMN azlc family GZ082_RS05675 ENOG4105GIJ Glycine betaine GZ082_RS05680 ENOG4108HQS Glycine betaine GZ082_RS05685 ENOG4108IJ7 Glycine betaine GZ082_RS05690 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GZ082_RS05695 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GZ082_RS05705 ENOG4105WAZ (Glutaredoxin-like protein) NrdH GZ082_RS05710 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) GZ082_RS05715 ENOG4108WMJ Protein of unknown function (DUF2002) GZ082_RS05720 ENOG4108RNS Exports L-alanine (By similarity) GZ082_RS05725 ENOG4108X73 DNA- binding protein GZ082_RS05730 ENOG4108V62 Rhodanese domain protein GZ082_RS05735 ENOG41080HT Transcriptional regulator, arsr family GZ082_RS05740 ENOG4105VPI YqaE family transport protein GZ082_RS05745 ENOG4109066 lysm domain bon superfamily protein GZ082_RS05750 ENOG4108PVQ transcriptional regulator GZ082_RS05755 ENOG4105C85 amino acid GZ082_RS05760 ENOG4108JPW Aminotransferase GZ082_RS05765 ENOG4105C26 Dehydrogenase GZ082_RS05770 ENOG4105D5U fad dependent oxidoreductase GZ082_RS05840 ENOG4108Z1B Cyclase dehydrase GZ082_RS05850 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GZ082_RS05855 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) GZ082_RS05875 ENOG4108JU6 CBS domain protein GZ082_RS05880 ENOG4106KVJ cytochrome C assembly protein GZ082_RS05885 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY GZ082_RS05910 ENOG41090EK ompa motb domain protein GZ082_RS05915 ENOG4108KHX Diguanylate cyclase GZ082_RS05920 ENOG4108WS1 GZ082_RS05925 ENOG4105QP9 Protein of unknown function (DUF2799) GZ082_RS05930 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GZ082_RS05935 ENOG4105EHE chorismate mutase- prephenate dehydrogenase GZ082_RS05940 ENOG4105CQC Prephenate dehydratase GZ082_RS05950 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA GZ082_RS05955 ENOG4105VNT transposase (IS4 family) protein GZ082_RS05960 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane GZ082_RS05965 ENOG4105C34 Pseudouridine synthase GZ082_RS05970 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase GZ082_RS05975 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GZ082_RS06000 ENOG4105CSH Transporter GZ082_RS06005 ENOG4105T42 (LipO)protein GZ082_RS06010 ENOG4105JIM Phosphatidylserine synthase GZ082_RS06020 ENOG4106IUH DTW domain containing protein GZ082_RS06025 ENOG4105K63 Thioredoxin GZ082_RS06030 ENOG4105EIB trna rrna methyltransferase GZ082_RS06050 ENOG41090KR LysR family transcriptional Regulator GZ082_RS06055 ENOG4105C1J atp-dependent rna helicase GZ082_RS06065 ENOG4108IYU L-aspartate oxidase GZ082_RS06075 ENOG4105EMN RNA polymerase sigma factor GZ082_RS06080 ENOG41069PW sigma-e factor negative regulatory protein GZ082_RS06085 ENOG4105VQK sigma E regulatory protein, MucB RseB GZ082_RS06090 ENOG4105WMJ Positive regulator of sigma E, RseC MucC GZ082_RS06100 ENOG4105C3F Signal peptidase i GZ082_RS06120 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) GZ082_RS06135 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding GZ082_RS06140 ENOG4106G6Q Transcriptional regulator GZ082_RS06145 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB GZ082_RS06150 ENOG4108Z6B deaminase GZ082_RS06165 ENOG4107WP9 Histidine kinase GZ082_RS06170 ENOG4108SKK alpha helix protein GZ082_RS06175 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GZ082_RS06185 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GZ082_RS06195 ENOG4108NZE NAGC-like transcriptional regulator GZ082_RS06200 ENOG4107HQ7 repeat protein GZ082_RS06205 ENOG4105FCA ABC transporter periplasmic-binding protein YphF GZ082_RS06210 ENOG4108F37 ATP-binding component of a transport system GZ082_RS06215 ENOG4105CNN ABC, transporter GZ082_RS06220 ENOG4105CPQ Dehydrogenase GZ082_RS06225 ENOG4108ZKT aldose 1-epimerase GZ082_RS06230 ENOG4108SB3 DoxX Family GZ082_RS06255 ENOG4105FUY alpha subunit GZ082_RS06260 ENOG4108W5M transcriptional regulator GZ082_RS06265 ENOG4105D8G Major Facilitator superfamily GZ082_RS06270 ENOG4108MN2 Stationary phase inducible protein CsiE GZ082_RS06275 ENOG4107XM9 (LipO)protein GZ082_RS06280 ENOG4105ECY inositol monophosphatase GZ082_RS06300 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins GZ082_RS06320 ENOG4108ZIT Ferredoxin, 2FE-2S GZ082_RS06325 ENOG4105WVQ Fe-S assembly protein IscX GZ082_RS06335 ENOG4105YYA enhanced serine sensitivity protein SseB GZ082_RS06340 ENOG4105KHC sulfurtransferase GZ082_RS06345 ENOG4105DN3 alpha-2-macroglobulin domain protein GZ082_RS06350 ENOG4108JQB penicillin-binding protein 1C GZ082_RS06380 ENOG4105N21 Membrane GZ082_RS06395 ENOG4105VPD cellular component movement GZ082_RS06405 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) GZ082_RS06415 ENOG41066DY Membrane GZ082_RS06420 ENOG4108ZMA Outer membrane lipoprotein GZ082_RS06430 ENOG41062G3 Protein of unknown function (DUF2633) GZ082_RS06440 ENOG4105BZU Histidine kinase GZ082_RS06445 ENOG4105C9X ppx gppa phosphatase GZ082_RS06450 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) GZ082_RS06455 ENOG4108V3E phosphoribosylglycinamide formyltransferase GZ082_RS06470 ENOG4105C2W permease GZ082_RS06475 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) GZ082_RS06480 ENOG4105K89 arsenate reductase GZ082_RS06485 ENOG4105ERG peptidase m48, ste24p GZ082_RS06490 ENOG4105C02 permease GZ082_RS06495 ENOG4105TMB Formate nitrite transporter GZ082_RS06500 ENOG4108JUA Transcriptional regulator GZ082_RS06505 ENOG4105I6X formate hydrogenlyase maturation GZ082_RS06510 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit GZ082_RS06520 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GZ082_RS06525 ENOG4108JPZ Monovalent cation H antiporter subunit D GZ082_RS06530 ENOG4107WQX hydrogenase 4 membrane subunit GZ082_RS06540 ENOG4105D65 subunit l GZ082_RS06545 ENOG4107TDF Formate hydrogenlyase subunit 4 GZ082_RS06550 ENOG4108JPZ Monovalent cation H antiporter subunit D GZ082_RS06555 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) GZ082_RS06560 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GZ082_RS06565 ENOG4105RH4 Glycine cleavage system transcriptional repressor GZ082_RS06575 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) GZ082_RS06590 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A GZ082_RS06595 ENOG4105CGZ zinc metallopeptidase GZ082_RS06605 ENOG4106KED esterase YpfH GZ082_RS06620 ENOG4105KUZ arsenate reductase GZ082_RS06630 ENOG4105BZS acriflavin resistance protein GZ082_RS06635 ENOG4105BZU Histidine kinase GZ082_RS06640 ENOG4105BZ8 glutamate synthase GZ082_RS06650 ENOG4108PVD exported protein GZ082_RS06655 ENOG4105CV1 Transketolase (EC 2.2.1.1) GZ082_RS06660 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GZ082_RS06665 ENOG4105C6K Malic enzyme GZ082_RS06670 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place GZ082_RS06675 ENOG4106S4J ethanolamine utilization protein EutP GZ082_RS06680 ENOG4105NDK ethanolamine utilization protein GZ082_RS06685 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase GZ082_RS06690 ENOG4107WUY phosphate acetyltransferase GZ082_RS06695 ENOG4105KNY Microcompartments protein GZ082_RS06700 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml GZ082_RS06705 ENOG4108EKI Dehydrogenase GZ082_RS06710 ENOG4107RWI ethanolamine utilization protein eutJ GZ082_RS06715 ENOG4105C0A alcohol dehydrogenase GZ082_RS06720 ENOG4105ENY Ethanolamine utilization protein eutH GZ082_RS06725 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase GZ082_RS06775 ENOG4105DFP Integrase GZ082_RS06780 ENOG4105CPD ethanolamine ammonia-lyase GZ082_RS06790 ENOG4106D67 ethanolamine utilization protein GZ082_RS06795 ENOG4108X49 Ethanolamine utilization protein EutK GZ082_RS06800 ENOG4108K3Z AraC family transcriptional regulator GZ082_RS06810 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase GZ082_RS06820 ENOG4105QZU Inner membrane protein YfeZ GZ082_RS06825 ENOG4105E7K (LipO)protein GZ082_RS06830 ENOG4105EZR dyp-type peroxidase family protein GZ082_RS06835 ENOG4107S1E Beta-lactamase GZ082_RS06840 ENOG4105C5Y PTS System GZ082_RS06855 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr GZ082_RS06860 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein GZ082_RS06865 ENOG4108I5D sulfate abc transporter GZ082_RS06870 ENOG4105ECW sulfate abc transporter GZ082_RS06875 ENOG4108IJ6 ABC transporter GZ082_RS06880 ENOG4105C6T cysteine synthase GZ082_RS06885 ENOG4105M0Y GZ082_RS06895 ENOG4105C5Y PTS System GZ082_RS06900 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GZ082_RS06910 ENOG4105C6T cysteine synthase GZ082_RS06930 ENOG4105VRT cytoplasmic protein GZ082_RS06935 ENOG4105DHU Bile acid GZ082_RS06940 ENOG4108M0I Transcriptional regulator GZ082_RS06975 ENOG4105GXM Putative transcription regulator (DUF1323) GZ082_RS06980 ENOG4105HZG regulatoR GZ082_RS06995 ENOG4108KMM Diguanylate cyclase GZ082_RS07000 ENOG4105D9N nucleoside GZ082_RS07010 ENOG4109076 Conserved Protein GZ082_RS07025 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) GZ082_RS07030 ENOG410863U PTS System GZ082_RS07035 ENOG4105DC7 peptidase M24 GZ082_RS07040 ENOG4105CN9 Peptidase m42 family protein GZ082_RS07045 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GZ082_RS07050 ENOG4108CIP transcriptional regulator GZ082_RS07055 ENOG4105DY9 regulatoR GZ082_RS07060 ENOG4108HRK Histidine kinase GZ082_RS07065 ENOG4105CHM Aminotransferase GZ082_RS07075 ENOG4105D1S lipid A biosynthesis GZ082_RS07080 ENOG4105W9M Membrane GZ082_RS07090 ENOG4108V08 YfdX protein GZ082_RS07100 ENOG4105CFN oxalyl-CoA decarboxylase GZ082_RS07105 ENOG4108N2Y auxin Efflux GZ082_RS07110 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F GZ082_RS07115 ENOG4105BZU Histidine kinase GZ082_RS07120 ENOG4108WQH regulatoR GZ082_RS07125 ENOG4105CW7 secretion protein, HlyD family GZ082_RS07130 ENOG4105C0R drug resistance transporter emrb qaca subfamily GZ082_RS07145 ENOG4106NDP Transcriptional regulator GZ082_RS07150 ENOG4108HKT sucrose-6-phosphate hydrolase GZ082_RS07155 ENOG4105D7K pfkb domain protein GZ082_RS07160 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) GZ082_RS07165 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles GZ082_RS07175 ENOG4108YGG dna repair protein GZ082_RS07180 ENOG4105MFG Antirestriction protein GZ082_RS07185 ENOG4106H6R UPF0380 protein GZ082_RS07200 ENOG4105F9F transposase GZ082_RS07240 ENOG4105C6F GntR Family Transcriptional Regulator GZ082_RS07290 ENOG4105CPQ Dehydrogenase GZ082_RS07295 ENOG4108I5G Major Facilitator superfamily GZ082_RS07330 ENOG4107QRT dEAD DEAH box helicase GZ082_RS07360 ENOG4105DFP Integrase GZ082_RS07370 ENOG4105S64 Formate nitrite transporter GZ082_RS07375 ENOG410903C (LipO)protein GZ082_RS07385 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation GZ082_RS07390 ENOG4105KZW UPF0381 protein GZ082_RS07405 ENOG4108BY2 phosphohistidine phosphatase GZ082_RS07420 ENOG4108FZ9 Chaperone GZ082_RS07425 ENOG4105NEV Fimbrial GZ082_RS07430 ENOG4105UGQ Fimbrial GZ082_RS07435 ENOG4105US4 fimbrial-like protein yfcP GZ082_RS07470 ENOG4105EJ9 Membrane GZ082_RS07475 ENOG4108BPE -transporting atpase GZ082_RS07480 ENOG4105MH2 YfcL protein GZ082_RS07485 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) GZ082_RS07490 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GZ082_RS07495 ENOG4105F9N Major Facilitator Superfamily GZ082_RS07500 ENOG4106WZ1 flagella biosynthesis regulator GZ082_RS07510 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) GZ082_RS07520 ENOG4105DQR SNARE associated Golgi GZ082_RS07530 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase GZ082_RS07535 ENOG4108S3P Sporulation domain protein GZ082_RS07540 ENOG4105E96 Colicin v production protein GZ082_RS07545 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase GZ082_RS07550 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase GZ082_RS07555 ENOG4105E89 ABC transporter GZ082_RS07560 ENOG4105E89 ABC transporter GZ082_RS07565 ENOG4105DSP amino acid AbC transporter GZ082_RS07570 ENOG4106YG3 ABC transporter GZ082_RS07575 ENOG4108JEH abc transporter atp-binding protein GZ082_RS07580 ENOG4105DNE Transposase GZ082_RS07585 ENOG4105ECP epimerase GZ082_RS07590 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase GZ082_RS07595 ENOG4105CYM Glutathione S-transferase GZ082_RS07600 ENOG4108SHQ Glutathione S-transferase GZ082_RS07605 ENOG4108RE9 Phosphodiesterase GZ082_RS07610 ENOG4105PTV Nudix Hydrolase GZ082_RS07615 ENOG4105CSX c4-dicarboxylate anaerobic carrier GZ082_RS07620 ENOG4105C6K Malic enzyme GZ082_RS07625 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GZ082_RS07635 ENOG4105XWI UPF0304 protein GZ082_RS07640 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 GZ082_RS07645 ENOG4107QWE )-transporter GZ082_RS07655 ENOG4105CHM Aminotransferase GZ082_RS07660 ENOG4107NQ8 LysR family Transcriptional regulator GZ082_RS07680 ENOG4105GKE subunit e GZ082_RS07685 ENOG4107QIZ NADH dehydrogenase GZ082_RS07690 ENOG4108IEH NADH dehydrogenase subunit g GZ082_RS07705 ENOG4107UFS subunit j GZ082_RS07715 ENOG4105D65 subunit l GZ082_RS07720 ENOG4105C8S subunit m GZ082_RS07730 ENOG4105GDX Domain of unknown function (DUF1877) GZ082_RS07750 ENOG4107YB6 acetyltransferase, (GNAT) family GZ082_RS07755 ENOG4105TNS Conserved Protein GZ082_RS07760 ENOG4105E4F Isochorismate synthase GZ082_RS07775 ENOG4108IPT Naphthoate synthase GZ082_RS07785 ENOG4105CEY Amp-dependent synthetase and ligase GZ082_RS07790 ENOG4106GZG polymyxin resistance protein B GZ082_RS07805 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) GZ082_RS07840 ENOG4108UII YfaZ family GZ082_RS07845 ENOG4108EWA cinA-like protein GZ082_RS07855 ENOG4105DNE Transposase GZ082_RS07860 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GZ082_RS07870 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A GZ082_RS07875 ENOG4105CXY transporter GZ082_RS07880 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase GZ082_RS07890 ENOG4105FQR PH-inducible protein involved in stress response GZ082_RS07895 ENOG4105XPH Ferredoxin GZ082_RS07900 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GZ082_RS07905 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) GZ082_RS07910 ENOG4107GHC outer membrane autotransporter GZ082_RS07920 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) GZ082_RS07925 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) GZ082_RS07930 ENOG4108QJJ Protein of unknown function (DUF1175) GZ082_RS07935 ENOG4107S52 alpha-2-macroglobulin domain protein GZ082_RS07940 ENOG41081SK signal peptide protein GZ082_RS07945 ENOG4105EDV vault protein GZ082_RS07950 ENOG4105BZU Histidine kinase GZ082_RS07955 ENOG41068CG regulatoR GZ082_RS07960 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC GZ082_RS07965 ENOG4105FCK Membrane GZ082_RS07970 ENOG4105CJ2 (LipO)protein GZ082_RS07975 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GZ082_RS07980 ENOG4105CF1 Alkylated DNA repair protein GZ082_RS07985 ENOG4105IBP Cyclic peptide transporter GZ082_RS08005 ENOG4108ZNS ferredoxin-type protein NapF GZ082_RS08010 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase GZ082_RS08020 ENOG4108BGM Quinol dehydrogenase periplasmic component GZ082_RS08025 ENOG4105GXZ Ferredoxin-type protein NapH GZ082_RS08030 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) GZ082_RS08035 ENOG4105CUW cytochrome C-TYPE protein GZ082_RS08040 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) GZ082_RS08045 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) GZ082_RS08050 ENOG41060IM Heme exporter protein GZ082_RS08055 ENOG4105X3C heme exporter protein GZ082_RS08065 ENOG4105DA4 cytochrome c-type biogenesis protein GZ082_RS08070 ENOG4107QX9 Thiol disulfide interChange protein GZ082_RS08075 ENOG4105KWW Biogenesis protein GZ082_RS08080 ENOG4105WH1 Two component transcriptional regulator luxr family GZ082_RS08095 ENOG4105E68 Sulfatase GZ082_RS08115 ENOG4105CFI type iii restriction protein res subunit GZ082_RS08120 ENOG4105I08 Pseudouridine synthase GZ082_RS08125 ENOG4105C2C drug resistance transporter, Bcr CflA GZ082_RS08130 ENOG4105HG6 GZ082_RS08135 ENOG4108JQ5 ABC transporter GZ082_RS08140 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component GZ082_RS08145 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component GZ082_RS08150 ENOG4105E43 Extracellular solute-binding protein, family 5 GZ082_RS08155 ENOG4105CXC rtn protein GZ082_RS08160 ENOG4107TT5 NLP P60 protein GZ082_RS08165 ENOG41076MN Phosphoesterase, PA-phosphatase related GZ082_RS08170 ENOG4105CKI cobalamin synthesis protein GZ082_RS08175 ENOG4105DEI Mannitol dehydrogenase GZ082_RS08185 ENOG4105KRS Proteinase inhibitor GZ082_RS08190 ENOG4105S8Q sugar efflux transporter GZ082_RS08195 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein GZ082_RS08200 ENOG4105DE4 1-phosphofructokinase GZ082_RS08205 ENOG4105DM4 PTS System GZ082_RS08210 ENOG4105DD7 kinase (PfkB family GZ082_RS08215 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) GZ082_RS08220 ENOG4105D9N nucleoside GZ082_RS08225 ENOG4108Y4K DNA-binding transcriptional activator GZ082_RS08235 ENOG4105D9N nucleoside GZ082_RS08240 ENOG4105DD7 kinase (PfkB family GZ082_RS08250 ENOG4105HMI Membrane GZ082_RS08255 ENOG4105DUM transcriptional regulator, lysR family GZ082_RS08260 ENOG4108IQI permease GZ082_RS08265 ENOG4105D05 Receptor GZ082_RS08280 ENOG4105DHF Membrane GZ082_RS08285 ENOG41060NJ transcriptional regulator GZ082_RS08290 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator GZ082_RS08295 ENOG4105C2J ABC transporter GZ082_RS08300 ENOG4108HWV )-transporter GZ082_RS08305 ENOG4107SJI Dehydrogenase GZ082_RS08310 ENOG4105BZ8 glutamate synthase GZ082_RS08315 ENOG4105Y9N Membrane GZ082_RS08320 ENOG4107GZ4 SanA protein GZ082_RS08330 ENOG41067MG lrgb family GZ082_RS08360 ENOG4108RXX maleylacetoacetate isomerase GZ082_RS08365 ENOG4105MSY salicylate hydroxylase GZ082_RS08370 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) GZ082_RS08380 ENOG4105ETP RND efflux system, outer membrane lipoprotein GZ082_RS08385 ENOG4105H9W Short-chain dehydrogenase reductase Sdr GZ082_RS08390 ENOG4105KHU inner membrane protein YohD GZ082_RS08395 ENOG41069YE inner membrane protein yohC GZ082_RS08400 ENOG41061WM D-Alanyl-D-Alanine GZ082_RS08405 ENOG4105CXG d-lactate dehydrogenase GZ082_RS08410 ENOG4107QK4 glycoside hydrolase, family 3 domain protein GZ082_RS08415 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system GZ082_RS08420 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component GZ082_RS08425 ENOG4108IJ8 ABC transporter GZ082_RS08430 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component GZ082_RS08440 ENOG4108XDN Transcriptional regulator GZ082_RS08445 ENOG4108HRK Histidine kinase GZ082_RS08450 ENOG4108NEV two component transcriptional regulator, LytTR family GZ082_RS08455 ENOG4108W15 Protein of unknown function (DUF1456) GZ082_RS08460 ENOG4108YCW (LipO)protein GZ082_RS08465 ENOG410903U zinc ion binding GZ082_RS08470 ENOG4105DEG Vwa containing coxe family protein GZ082_RS08475 ENOG4105RD5 GZ082_RS08480 ENOG4105KKX ATPase associated with various cellular activities aaa_5 GZ082_RS08495 ENOG4108KDT Molybdate metabolism regulator GZ082_RS08505 ENOG4105D1F ATP-binding protein GZ082_RS08510 ENOG41067AK Protein of unknown function (DUF2574) GZ082_RS08515 ENOG41063W2 Fimbrial protein GZ082_RS08520 ENOG4108MQF Chaperone GZ082_RS08525 ENOG4105CW0 outer membrane usher protein GZ082_RS08530 ENOG410662B Type-1 fimbrial protein GZ082_RS08535 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly GZ082_RS08555 ENOG4105VNT transposase (IS4 family) protein GZ082_RS08575 ENOG4105DWF phosphomethylpyrimidine kinase GZ082_RS08580 ENOG4108UQ1 hydrolase, family 25 GZ082_RS08585 ENOG4105FDP GntR family transcriptional regulator GZ082_RS08590 ENOG4108TFM Kinase, PfkB family GZ082_RS08595 ENOG4108KD5 ADP-ribosylation crystallin J1 GZ082_RS08600 ENOG4105EAA nucleoside GZ082_RS08605 ENOG4105EIE fructose-bisphosphate aldolase GZ082_RS08620 ENOG41082GB PTS system galactitol-specific transporter subunit IIA GZ082_RS08625 ENOG41090UW PTS System GZ082_RS08630 ENOG4105DT3 PTS system, galactitol-specific IIc component GZ082_RS08635 ENOG4107WTH Galactitol-1-phosphate dehydrogenase GZ082_RS08650 ENOG41076Z6 Uncharacterized protein yegR GZ082_RS08655 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GZ082_RS08700 ENOG4105VZ1 Replication Protein GZ082_RS08710 ENOG4105ED4 portal protein GZ082_RS08860 ENOG4105ZTC transcriptional activator, Ogr delta GZ082_RS08865 ENOG4105CFP Peptidase U32 GZ082_RS08875 ENOG4105X54 addiction module antidote protein GZ082_RS08880 ENOG4105KWI UPF0339 protein GZ082_RS08885 ENOG4105E3W Two component transcriptional regulator (Winged helix family GZ082_RS08890 ENOG4105EB3 Histidine kinase GZ082_RS08925 ENOG4108M24 von Willebrand factor, type A GZ082_RS08930 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase GZ082_RS08935 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding GZ082_RS08940 ENOG4105R8A Heat shock protein GZ082_RS08945 ENOG4105D03 DNA-3-methyladenine glycosylase II GZ082_RS08955 ENOG4105DBI uridine monophosphokinase GZ082_RS08965 ENOG4108GAE asmA family GZ082_RS08970 ENOG4105EE5 Membrane protein terC GZ082_RS08980 ENOG4105DAY polysaccharide export protein GZ082_RS08985 ENOG4105KJF protein tyrosine phosphatase GZ082_RS08990 ENOG4105D75 Capsular exopolysaccharide family GZ082_RS08995 ENOG41090RK glycosyl transferase GZ082_RS09000 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB GZ082_RS09005 ENOG4107RXY Glycosyl transferase GZ082_RS09010 ENOG4108NYJ Colanic acid GZ082_RS09015 ENOG4105ECJ Glycosyl Transferase GZ082_RS09020 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF GZ082_RS09025 ENOG4105C0K Gdp-mannose 4,6-dehydratase GZ082_RS09030 ENOG4105C30 Nad-dependent epimerase dehydratase GZ082_RS09035 ENOG4105FGF GDP-mannose mannosyl hydrolase GZ082_RS09040 ENOG4106CD9 glycosyl transferase group 1 GZ082_RS09045 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GZ082_RS09050 ENOG4107QKV phosphomannomutase GZ082_RS09055 ENOG4105D3Q Sugar transferase GZ082_RS09060 ENOG4105PSV Polysaccharide Biosynthesis Protein GZ082_RS09065 ENOG4105C74 pyruvyl transferase GZ082_RS09070 ENOG4107T8Q Glycosyl transferase (Group 1 GZ082_RS09075 ENOG4105G1A colanic acid biosynthesis protein GZ082_RS09080 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GZ082_RS09115 ENOG4105CMR udp-glucose 4-epimerase GZ082_RS09120 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) GZ082_RS09125 ENOG4105C6Y Udp-glucose 6-dehydrogenase GZ082_RS09130 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) GZ082_RS09135 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase GZ082_RS09150 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) GZ082_RS09155 ENOG4105ECC imidazole-glycerol-phosphate dehydratase GZ082_RS09160 ENOG4105CIH Imidazole acetol-phosphate transaminase GZ082_RS09180 ENOG4107SRH Nad-dependent epimerase dehydratase GZ082_RS09185 ENOG4105EQ1 Transcriptional regulator GZ082_RS09195 ENOG4105CUB amino acid GZ082_RS09200 ENOG4105CUC YeeE YedE family protein GZ082_RS09210 ENOG4105CJB Exodeoxyribonuclease I GZ082_RS09215 ENOG4105DZ1 carboxypeptidase GZ082_RS09225 ENOG4105DR8 Membrane GZ082_RS09280 ENOG4108YZT Adenosylcobinamide kinase GZ082_RS09295 ENOG4108PXI ErfK YbiS YcfS YnhG GZ082_RS09305 ENOG4106P55 Transcriptional regulator GZ082_RS09310 ENOG4107R11 Transcriptional regulator GZ082_RS09320 ENOG4105UQX Mate efflux family protein GZ082_RS09330 ENOG4105CDY transcriptional regulatory protein GZ082_RS09335 ENOG4105FYV Amp nucleosidase GZ082_RS09340 ENOG4105CSH Transporter GZ082_RS09365 ENOG4105TNG K13735 adhesin invasin GZ082_RS09370 ENOG4107ZSV Receptor GZ082_RS09375 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase GZ082_RS09395 ENOG4105C0W non-ribosomal peptide synthetase GZ082_RS09415 ENOG4105BZ1 (ABC) transporter GZ082_RS09420 ENOG4105EYM Major Facilitator superfamily GZ082_RS09450 ENOG4108MEK Metal-binding protein YodA GZ082_RS09455 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) GZ082_RS09465 ENOG4105VT2 5-hydroxyisourate hydrolase GZ082_RS09470 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GZ082_RS09475 ENOG4107ZY3 Histidine kinase GZ082_RS09480 ENOG4105TMR Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity) GZ082_RS09490 ENOG4105FCK Membrane GZ082_RS09495 ENOG4105Y0K Inner membrane protein YedR GZ082_RS09500 ENOG4105EST Metal Dependent Phosphohydrolase GZ082_RS09505 ENOG4105DVF Cytosine-specific methyltransferase GZ082_RS09510 ENOG41090BB DNA mismatch endonuclease (vsr) GZ082_RS09515 ENOG4105FDR Membrane GZ082_RS09520 ENOG4105CKW Inner membrane protein yedI GZ082_RS09525 ENOG4105VNZ cytoplasmic protein GZ082_RS09530 ENOG4105BZU Histidine kinase GZ082_RS09540 ENOG4105YX3 cellular response to acidity GZ082_RS09550 ENOG4107TKS colanic acid capsular biosynthesis activation protein A GZ082_RS09555 ENOG4105D19 Role in flagellar biosynthesis (By similarity) GZ082_RS09565 ENOG4105CN7 Flagellar biosynthetic protein FliP GZ082_RS09570 ENOG4105K0P flagellar biosynthesis protein GZ082_RS09575 ENOG4105DD5 Flagellar motor switch protein GZ082_RS09580 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GZ082_RS09585 ENOG4107ZI8 flagellar basal body-associated protein flil GZ082_RS09590 ENOG4105WF4 Flagellar hook-length control protein GZ082_RS09595 ENOG4105GSA Flagellar export protein flij GZ082_RS09600 ENOG4108JIR Flagellum-specific ATP synthase GZ082_RS09605 ENOG41090PJ Flagellar assembly protein GZ082_RS09610 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) GZ082_RS09615 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) GZ082_RS09620 ENOG4105VQ0 flagellar hook-basal body complex protein fliE GZ082_RS09625 ENOG410814C multidrug resistance protein GZ082_RS09630 ENOG4108V1U phospholipid-binding protein GZ082_RS09635 ENOG4108UQN AraC family transcriptional regulator GZ082_RS09645 ENOG4105D7V transposase GZ082_RS09650 ENOG4108RAV Conserved protein GZ082_RS09660 ENOG41066VF YeeE YedE family protein GZ082_RS09665 ENOG4108W9D (LipO)protein GZ082_RS09670 ENOG4105E5K Alpha-amylase GZ082_RS09680 ENOG4105MQ3 flagellar protein FliS GZ082_RS09685 ENOG4105DTS flagellar hook-associated GZ082_RS09695 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GZ082_RS09700 ENOG4108M9K flagella biosynthesis protein FliZ GZ082_RS09705 ENOG4105EAB amino acid AbC transporter GZ082_RS09710 ENOG4105K6H D-cysteine desulfhydrase GZ082_RS09715 ENOG4105E5Q amino acid AbC transporter GZ082_RS09720 ENOG4105CDA abc transporter atp-binding protein GZ082_RS09725 ENOG4105VJY transcriptional regulator GZ082_RS09730 ENOG4105XVG cytoplasmic protein GZ082_RS09740 ENOG4105WH1 Two component transcriptional regulator luxr family GZ082_RS09770 ENOG4106RHG Yeca family GZ082_RS09775 ENOG4105E0U tyrosine-specific transport protein GZ082_RS09780 ENOG4105VVZ metal-binding protein GZ082_RS09785 ENOG41090A1 ferritin GZ082_RS09790 ENOG4105P23 (LipO)protein GZ082_RS09800 ENOG4105N4N Protein of unknown function (DUF2766) GZ082_RS09805 ENOG4108UEC Ferritin-like protein GZ082_RS09810 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator GZ082_RS09815 ENOG4105C2J ABC transporter GZ082_RS09820 ENOG4105CNN ABC, transporter GZ082_RS09825 ENOG4108K4C ec 3.1.3.12 GZ082_RS09835 ENOG4108VA4 Universal stress protein GZ082_RS09845 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region GZ082_RS09850 ENOG4107RD7 Flagellar Motor Protein, MotA GZ082_RS09855 ENOG4105ER2 Ompa motb domain protein GZ082_RS09860 ENOG4105CBS Chea signal transduction histidine kinase GZ082_RS09865 ENOG4108V3W Chemotaxis protein, CheW GZ082_RS09870 ENOG4105C8Q Methyl-accepting chemotaxis GZ082_RS09875 ENOG4105C8Q Methyl-accepting chemotaxis GZ082_RS09880 ENOG4105BZU Histidine kinase GZ082_RS09885 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) GZ082_RS09890 ENOG4108VYJ response regulator receiver protein GZ082_RS09895 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) GZ082_RS09900 ENOG4105D00 flagellar biosynthetic protein flhB GZ082_RS09905 ENOG4105D7B Flagellar biosynthesis protein flha GZ082_RS09910 ENOG4105W13 flagellar protein GZ082_RS09925 ENOG4106ZCM YecM protein GZ082_RS09935 ENOG4105CUW cytochrome C-TYPE protein GZ082_RS09940 ENOG4108J2R molybdopterin oxidoreductase GZ082_RS09955 ENOG4105WJG Glutathione GZ082_RS09960 ENOG41081XQ Conserved Protein GZ082_RS09965 ENOG4105D3W isochorismatase GZ082_RS09975 ENOG4108TIT dATP pyrophosphohydrolase GZ082_RS09980 ENOG4105CDY transcriptional regulatory protein GZ082_RS09990 ENOG4107S01 Repressor protein MetJ GZ082_RS10010 ENOG4105FAV ABC, transporter GZ082_RS10020 ENOG4105NXV High-affinity zinc uptake system protein GZ082_RS10025 ENOG4105DR5 peptidase GZ082_RS10030 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase GZ082_RS10050 ENOG4108IJ9 (ABC) transporter GZ082_RS10060 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GZ082_RS10070 ENOG4107FKK extracellular solute-binding protein family 1 GZ082_RS10075 ENOG4105D56 permease protein GZ082_RS10080 ENOG4105EG2 ABC transporter, permease GZ082_RS10105 ENOG4105CA9 Pyruvate kinase GZ082_RS10110 ENOG4106KNT transcriptional regulator GZ082_RS10115 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase GZ082_RS10120 ENOG4105C01 Dihydroxy-acid dehydratase GZ082_RS10125 ENOG4108UHU Aldolase GZ082_RS10135 ENOG4105X2V dna damage-inducible protein GZ082_RS10145 ENOG4108Q2J Inner membrane protein YebE GZ082_RS10150 ENOG4105CUG Oligopeptidase b GZ082_RS10155 ENOG4105UMD exodeoxyribonuclease X GZ082_RS10160 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GZ082_RS10165 ENOG4105MPK DNA polymerase III subunit theta GZ082_RS10170 ENOG4105FXM Copper resistance protein GZ082_RS10175 ENOG4108PNC copper resistance GZ082_RS10180 ENOG4105NKT exported protein GZ082_RS10185 ENOG4108R1E Serine threonine protein phosphatase 1 GZ082_RS10190 ENOG4105UVW uncharacterized protein yebW GZ082_RS10195 ENOG4105WT8 Protein of unknown function (DUF1480) GZ082_RS10205 ENOG4105DY2 Paraquat-inducible protein b GZ082_RS10210 ENOG4105H2K paraquat-inducible protein a GZ082_RS10215 ENOG4108ZGC gaf domain protein GZ082_RS10225 ENOG4105CN1 protease GZ082_RS10235 ENOG4105C0R drug resistance transporter emrb qaca subfamily GZ082_RS10240 ENOG4105J4Q Transcriptional regulator GZ082_RS10245 ENOG4105TIK GZ082_RS10255 ENOG4105Q3Y exported protein GZ082_RS10270 ENOG4105DHI Methyltransferase GZ082_RS10285 ENOG4105F3R pts system mannose fructose sorbose family iid GZ082_RS10290 ENOG4105ETZ PTS System GZ082_RS10295 ENOG4105DAS pts system GZ082_RS10300 ENOG4105EE5 Membrane protein terC GZ082_RS10305 ENOG4107XTP (EAL) domain protein GZ082_RS10310 ENOG4105EJQ L-serine dehydratase GZ082_RS10320 ENOG4105CRQ synthase (Component I) GZ082_RS10330 ENOG4105V2F Uncharacterized protein yoac GZ082_RS10335 ENOG4105M4H endoribonuclease L-psp GZ082_RS10340 ENOG4105DVT helicase GZ082_RS10345 ENOG41072GX Peptidase M22 Glycoprotease GZ082_RS10350 ENOG4105Y4Z Outer Membrane Lipoprotein GZ082_RS10355 ENOG4105CEY Amp-dependent synthetase and ligase GZ082_RS10360 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) GZ082_RS10365 ENOG4105E3J oxidoreductase GZ082_RS10370 ENOG4105DVW rieske (2Fe-2S) GZ082_RS10375 ENOG4105C94 Transporter GZ082_RS10380 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) GZ082_RS10385 ENOG4105EJC lysr family transcriptional regulator GZ082_RS10395 ENOG4108YS1 cytoplasmic protein GZ082_RS10400 ENOG4105YP6 Domain of unknown function (DUF1869) GZ082_RS10410 ENOG4105D7V transposase GZ082_RS10415 ENOG4105Y3U Transglycosylase-associated protein GZ082_RS10425 ENOG4106G4W GZ082_RS10430 ENOG410620I Diguanylate cyclase GZ082_RS10435 ENOG4105UCG Domain of unknown function (DUF333) GZ082_RS10440 ENOG4105K78 MarR family Transcriptional regulator GZ082_RS10445 ENOG4105DJ2 Major Facilitator Superfamily GZ082_RS10450 ENOG4105R1U AraC Family Transcriptional Regulator GZ082_RS10465 ENOG4108KXH Ybak prolyl-tRNA synthetase associated GZ082_RS10470 ENOG4108KHP Diguanylate cyclase GZ082_RS10475 ENOG4106KTS Inner membrane protein yeaI GZ082_RS10485 ENOG4105CYN Serine protein kinase GZ082_RS10490 ENOG4105GNX MltA-interacting MipA family protein GZ082_RS10495 ENOG4105CV8 reductase GZ082_RS10500 ENOG4105DSB aldose 1-epimerase GZ082_RS10505 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GZ082_RS10515 ENOG4105VUT cytoplasmic protein GZ082_RS10520 ENOG4105CPQ Dehydrogenase GZ082_RS10525 ENOG4107TE1 transport protein GZ082_RS10530 ENOG4105CPQ Dehydrogenase GZ082_RS10535 ENOG4105D2N Aldolase GZ082_RS10540 ENOG4107UH8 sugar kinase GZ082_RS10545 ENOG4105CPC Aldo Keto reductase GZ082_RS10550 ENOG4105E98 transcriptional regulator DeoR family GZ082_RS10555 ENOG4108KUU Inner membrane metabolite transport protein ydjE GZ082_RS10560 ENOG4108RWI nicotinamidase GZ082_RS10565 ENOG4105HDK L-asparaginase GZ082_RS10570 ENOG4105D07 Signal peptide peptidase, SppA GZ082_RS10575 ENOG41069NU Nitroreductase GZ082_RS10585 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GZ082_RS10595 ENOG4105D82 Glutamate dehydrogenase GZ082_RS10600 ENOG4105MTM Protein of unknown function (DUF1496) GZ082_RS10605 ENOG4105M6F mutator MutT protein GZ082_RS10610 ENOG4108T9J Cdp-alcohol phosphatidyltransferase GZ082_RS10615 ENOG4107RM6 sulfurtransferase GZ082_RS10620 ENOG4108VGW abc transporter atp-binding protein GZ082_RS10625 ENOG4105CXZ ABC transporter, permease GZ082_RS10630 ENOG4105VNH ABC transporter solute-binding protein GZ082_RS10635 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) GZ082_RS10640 ENOG4108N5C SNARE associated Golgi protein-related protein GZ082_RS10645 ENOG4108KCW iron-sulfur cluster binding GZ082_RS10650 ENOG4108RSN SNARE associated Golgi GZ082_RS10655 ENOG4105CGK Exodeoxyribonuclease III GZ082_RS10685 ENOG4108SPG Periplasmic Protein GZ082_RS10695 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) GZ082_RS10705 ENOG4105KKI DNA-binding transcriptional activator OsmE GZ082_RS10710 ENOG4105VZJ PTS System GZ082_RS10715 ENOG4105CK1 PTS System GZ082_RS10720 ENOG4105VCP PTS System GZ082_RS10725 ENOG4105EZV Transcriptional regulator GZ082_RS10730 ENOG4105F8D glycoside hydrolase family 4 GZ082_RS10740 ENOG4105CH6 catalase GZ082_RS10760 ENOG4108ETY sodium dicarboxylate symporter GZ082_RS10765 ENOG4107K5X Membrane-bound metal-dependent hydrolase GZ082_RS10770 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 GZ082_RS10775 ENOG4107PN8 YfeABCD locus regulator GZ082_RS10785 ENOG4105P10 Uncharacterized protein ydiZ GZ082_RS10790 ENOG4105DE4 1-phosphofructokinase GZ082_RS10795 ENOG4108NE3 Salt-induced outer membrane protein GZ082_RS10815 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) GZ082_RS10820 ENOG41082NX 50s ribosomal protein l35 GZ082_RS10900 ENOG4108C33 Resolvase GZ082_RS10910 ENOG4105PTU response to oxidative stress GZ082_RS10915 ENOG4108US3 tail fiber assembly GZ082_RS11000 ENOG4105ED4 portal protein GZ082_RS11015 ENOG4105VZ1 Replication Protein GZ082_RS11080 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GZ082_RS11100 ENOG4108V06 Glutathione peroxidase GZ082_RS11110 ENOG4108QBX (LipO)protein GZ082_RS11115 ENOG4108TC0 Diguanylate phosphodiesterase GZ082_RS11130 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GZ082_RS11140 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) GZ082_RS11150 ENOG41090P5 ferredoxin-like protein GZ082_RS11155 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GZ082_RS11160 ENOG4105C10 Electron transfer flavoprotein GZ082_RS11165 ENOG4105CV7 Electron transfer flavoprotein GZ082_RS11170 ENOG4105W4W Transcriptional regulator GZ082_RS11175 ENOG4105C1G acyl-Coa dehydrogenase GZ082_RS11180 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) GZ082_RS11195 ENOG4105EMV Major Facilitator GZ082_RS11200 ENOG4105EMV Major Facilitator GZ082_RS11205 ENOG4105SUA Ydil protein GZ082_RS11215 ENOG4105IPI Membrane GZ082_RS11220 ENOG4105CQB FAD linked oxidase domain protein GZ082_RS11225 ENOG4105KA0 thioesterase Superfamily protein GZ082_RS11230 ENOG410671Z uncharacterized protein ydiH GZ082_RS11235 ENOG4108Z4V iron-sulfur cluster assembly GZ082_RS11240 ENOG4105DIW FeS assembly protein SUFB GZ082_RS11245 ENOG4105C3K feS assembly ATPase SufC GZ082_RS11250 ENOG4105JRK feS assembly protein SufD GZ082_RS11265 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GZ082_RS11270 ENOG4105KMX major outer membrane lipoprotein GZ082_RS11275 ENOG4105CA9 Pyruvate kinase GZ082_RS11280 ENOG4105RFR Protein of unknown function (DUF2767) GZ082_RS11285 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein GZ082_RS11290 ENOG4105WE2 aldehyde ferredoxin oxidoreductase GZ082_RS11295 ENOG4105JVW GZ082_RS11300 ENOG4108393 oxidoreductase Fe-S subunit GZ082_RS11305 ENOG4108NWD Cytochrome GZ082_RS11310 ENOG4108Y7C Conserved Protein GZ082_RS11315 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain GZ082_RS11320 ENOG4105N0V mono-oxygenase ydhR GZ082_RS11345 ENOG4108R6K riboflavin synthase, subunit alpha GZ082_RS11350 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase GZ082_RS11355 ENOG4105CZQ inner membrane transport protein YdhC GZ082_RS11360 ENOG4105F52 Transcriptional regulator GZ082_RS11375 ENOG4105F27 Major Facilitator GZ082_RS11380 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GZ082_RS11385 ENOG4105K4H Nlp p60 protein GZ082_RS11390 ENOG4105M2J Glutaredoxin GZ082_RS11395 ENOG4107QRT dEAD DEAH box helicase GZ082_RS11405 ENOG4108UYE Lactoylglutathione lyase GZ082_RS11410 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GZ082_RS11415 ENOG4108WUH Transcriptional regulator, TetR family GZ082_RS11420 ENOG4105XZD Fe-S protein GZ082_RS11425 ENOG4107RGM aldo keto reductase GZ082_RS11430 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GZ082_RS11435 ENOG4105DSW Fusaric acid resistance protein GZ082_RS11440 ENOG4105Y49 secretion protein, HlyD family GZ082_RS11455 ENOG4108XTF Outer Membrane Lipoprotein GZ082_RS11465 ENOG410642K Lysozyme inhibitor GZ082_RS11480 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) GZ082_RS11485 ENOG4108K3A Glutathione S-transferase GZ082_RS11490 ENOG4105DUX Transporter GZ082_RS11495 ENOG4105CSM endonuclease III GZ082_RS11505 ENOG4108UQQ Electron transport complex GZ082_RS11530 ENOG4105M9B inner membrane protein ydgK GZ082_RS11535 ENOG4105QZ5 OriC-binding nucleoid-associated protein GZ082_RS11540 ENOG4106C6R beta-lactam resistance protein GZ082_RS11545 ENOG4105D9R oxidoreductase GZ082_RS11555 ENOG4105C87 Aminotransferase class I and II GZ082_RS11560 ENOG4105CI1 PTS System GZ082_RS11565 ENOG4107P2S Transcriptional regulator GZ082_RS11570 ENOG4107ZQV short-chain dehydrogenase reductase GZ082_RS11575 ENOG4105XEA Tetr family transcriptional regulator GZ082_RS11580 ENOG4105CNT hydrolase family 2 GZ082_RS11585 ENOG4105CT4 transporter GZ082_RS11590 ENOG4108QNI outer membrane porin protein GZ082_RS11595 ENOG4106J39 exported protein GZ082_RS11600 ENOG4105EIP mannose-6-phosphate isomerase GZ082_RS11605 ENOG4107GFK fumarate GZ082_RS11610 ENOG4105C9Q fumarate hydratase class II GZ082_RS11620 ENOG4105JJR Histidine kinase GZ082_RS11625 ENOG4107EXC regulatoR GZ082_RS11630 ENOG4105RA2 Membrane GZ082_RS11640 ENOG4105D5Q Arginine ornithine antiporter GZ082_RS11645 ENOG4105C5D exported protein GZ082_RS11650 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GZ082_RS11655 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GZ082_RS11660 ENOG4105DSF transport protein GZ082_RS11675 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap GZ082_RS11690 ENOG4105D94 Major Facilitator Superfamily GZ082_RS11695 ENOG4106NZI LysR family Transcriptional regulator GZ082_RS11700 ENOG4105DAG ROK family GZ082_RS11705 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GZ082_RS11715 ENOG4108NEM leader-binding protein dmsD GZ082_RS11720 ENOG4107KGK dmso reductase anchor subunit GZ082_RS11725 ENOG4105QAX Iron-sulfur GZ082_RS11730 ENOG4105C3J Cysteine desulfurase GZ082_RS11735 ENOG4107QY8 reductase GZ082_RS11740 ENOG4105KBG Protein of unknown function (DUF1161) GZ082_RS11745 ENOG4105D69 UPF0257 lipoprotein ynfC GZ082_RS11750 ENOG4108MK9 spermidine N(1)-acetyltransferase GZ082_RS11765 ENOG4105CXK mandelate racemase muconate lactonizing GZ082_RS11770 ENOG4105CPQ Dehydrogenase GZ082_RS11780 ENOG4105DEI Mannitol dehydrogenase GZ082_RS11785 ENOG41061EV selenium-binding protein YdfZ GZ082_RS11790 ENOG4107XBN GntR Family Transcriptional Regulator GZ082_RS11795 ENOG4105EMU Dehydrogenase GZ082_RS11800 ENOG4105DGW oligopeptidase A GZ082_RS11805 ENOG4108WTK competence damage-inducible protein GZ082_RS11810 ENOG4108YDI single-species biofilm formation on inanimate substrate GZ082_RS11815 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria GZ082_RS11825 ENOG4105E5W Transporter GZ082_RS11830 ENOG4108594 Permease of the drug metabolite transporter GZ082_RS11835 ENOG4105FDP GntR family transcriptional regulator GZ082_RS11845 ENOG4105CK1 PTS System GZ082_RS11850 ENOG4105VCP PTS System GZ082_RS11860 ENOG4105CS2 ec 3.2.1.21 GZ082_RS11865 ENOG4106DNR multiple antibiotic resistance protein GZ082_RS11870 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF GZ082_RS11875 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes GZ082_RS11895 ENOG4105EGI Transcriptional regulator GZ082_RS11900 ENOG4105C26 Dehydrogenase GZ082_RS11905 ENOG4105CSV Glutaminase GZ082_RS11910 ENOG4105M0C cytoplasmic protein GZ082_RS11915 ENOG4105BZU Histidine kinase GZ082_RS11925 ENOG4105FFC UPF0187 protein GZ082_RS11930 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) GZ082_RS11935 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound GZ082_RS11960 ENOG4105C2J ABC transporter GZ082_RS11980 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein GZ082_RS11985 ENOG4105CAF HipA N-terminal domain protein GZ082_RS11995 ENOG4108RQP Major type 1 subunit fimbrin GZ082_RS12005 ENOG4105CW0 outer membrane usher protein GZ082_RS12010 ENOG4108WDE Fimbrial protein GZ082_RS12015 ENOG4106318 fimbrial-like protein YdeR GZ082_RS12020 ENOG4106PIH fimbrial-like protein ydeQ GZ082_RS12030 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit GZ082_RS12040 ENOG4105Z68 AraC Family Transcriptional Regulator GZ082_RS12045 ENOG4105ENH Sulfatase GZ082_RS12050 ENOG4105C4X radical SAM domain protein GZ082_RS12060 ENOG4105CQ0 ABC transporter GZ082_RS12065 ENOG4105PE1 Receptor GZ082_RS12070 ENOG4107RAN Peptidase, M16 GZ082_RS12075 ENOG4105CVK Glutamate decarboxylase GZ082_RS12080 ENOG4105E5D amino acid GZ082_RS12085 ENOG4105F32 YngK protein GZ082_RS12095 ENOG4105BZU Histidine kinase GZ082_RS12100 ENOG4108UQS dipeptidase GZ082_RS12105 ENOG4105DEF Extracellular solute-binding protein, family 5 GZ082_RS12110 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GZ082_RS12115 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GZ082_RS12120 ENOG4105C3U ABC transporter GZ082_RS12125 ENOG4107H6U ABC transporter GZ082_RS12130 ENOG4105DUM transcriptional regulator, lysR family GZ082_RS12135 ENOG4107QP7 CoA-transferase subunit A GZ082_RS12140 ENOG4107QNJ CoA-transferase subunit B GZ082_RS12145 ENOG4105CHU acetyl-coa acetyltransferase GZ082_RS12150 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase GZ082_RS12155 ENOG4105CY2 Citrate transporter GZ082_RS12160 ENOG4105DTD Dehydrogenase GZ082_RS12165 ENOG4108Z9K Osmotically inducible protein GZ082_RS12170 ENOG4105TPS biofilm-dependent modulation protein GZ082_RS12175 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein GZ082_RS12185 ENOG4105DQ4 alcohol dehydrogenase GZ082_RS12190 ENOG41084S7 Plasmid maintenance system antidote protein GZ082_RS12195 ENOG4108MG3 formate dehydrogenase GZ082_RS12200 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GZ082_RS12210 ENOG4105RPH Inner membrane protein YddG GZ082_RS12220 ENOG4108UI3 Leucine Rich repeat GZ082_RS12225 ENOG4107QND Nitrite extrusion protein GZ082_RS12230 ENOG4105CRU nitrate reductase, alpha subunit GZ082_RS12235 ENOG4108IUE nitrate reductase beta subunit GZ082_RS12240 ENOG4108NZN Respiratory nitrate reductase 2 delta chain GZ082_RS12245 ENOG4105D0D Nitrate reductase 2, gamma subunit GZ082_RS12250 ENOG4105JAB phenazine biosynthesis protein, phzf family GZ082_RS12255 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase GZ082_RS12260 ENOG4108MEJ flavin reductase domain protein GZ082_RS12290 ENOG4105CNA YD repeat protein GZ082_RS12295 ENOG4105CS6 Rhs element vgr protein GZ082_RS12305 ENOG4108N27 Glutathione S-transferase GZ082_RS12310 ENOG4105C85 amino acid GZ082_RS12315 ENOG4108NS2 receptor GZ082_RS12320 ENOG4105CHB tonB-dependent Receptor GZ082_RS12330 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein GZ082_RS12335 ENOG4108Z7F N-acetyltransferase GZ082_RS12340 ENOG4108T9Y Inner membrane protein ydcZ GZ082_RS12345 ENOG4105R71 cytoplasmic protein GZ082_RS12350 ENOG410654E Membrane GZ082_RS12365 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component GZ082_RS12370 ENOG4105D81 ABC transporter, permease GZ082_RS12375 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GZ082_RS12380 ENOG4107TYH extracellular solute-binding protein family 1 GZ082_RS12385 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GZ082_RS12390 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin GZ082_RS12400 ENOG4105RR0 Protein of unknown function (DUF2554) GZ082_RS12405 ENOG4105CFP Peptidase U32 GZ082_RS12410 ENOG4108JCI Transcriptional regulator GZ082_RS12415 ENOG4105DKK Benzoate GZ082_RS12420 ENOG4105D7V transposase GZ082_RS12430 ENOG4108KKZ (LipO)protein GZ082_RS12435 ENOG41088CC tellurite resistance protein tehB GZ082_RS12440 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein GZ082_RS12445 ENOG4107WE3 acetyltransferase YdcK GZ082_RS12450 ENOG4108Z9I -acetyltransferase GZ082_RS12455 ENOG4105Z2P Protein of unknown function (DUF465) GZ082_RS12465 ENOG4105E32 cytoplasmic protein GZ082_RS12470 ENOG4105DDW LysR family Transcriptional regulator GZ082_RS12475 ENOG4105C8Q Methyl-accepting chemotaxis GZ082_RS12480 ENOG4107NK6 Hok/gef family GZ082_RS12485 ENOG4105UPP uncharacterized protein ydcA GZ082_RS12490 ENOG4105CPW cytochrome b561 GZ082_RS12495 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GZ082_RS12500 ENOG4105C26 Dehydrogenase GZ082_RS12505 ENOG4107DB1 DUF218 domain GZ082_RS12510 ENOG4105CQ7 ATP-dependent helicase GZ082_RS12520 ENOG41077RS Phosphatase GZ082_RS12525 ENOG4105E8V Alpha Beta Hydrolase Fold protein GZ082_RS12530 ENOG4108HPI phosphatidate Cytidylyltransferase GZ082_RS12535 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase GZ082_RS12545 ENOG4107S5I aldo keto reductase GZ082_RS12550 ENOG4108Z0R Transferase GZ082_RS12555 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein GZ082_RS12560 ENOG4105DZS Phenylacetate-CoA ligase GZ082_RS12565 ENOG4105CHU acetyl-coa acetyltransferase GZ082_RS12570 ENOG4108ZJI phenylacetic acid degradation protein GZ082_RS12575 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase GZ082_RS12580 ENOG4108UKI Enoyl-CoA hydratase GZ082_RS12585 ENOG4105E39 Enoyl-CoA hydratase GZ082_RS12590 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GZ082_RS12595 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit GZ082_RS12600 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit GZ082_RS12605 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit GZ082_RS12610 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit GZ082_RS12615 ENOG4105DXM phenylacetic acid degradation protein GZ082_RS12620 ENOG4105F11 amine oxidase GZ082_RS12625 ENOG4105C26 Dehydrogenase GZ082_RS12630 ENOG4108WFR AraC Family Transcriptional Regulator GZ082_RS12635 ENOG4105WXT Conserved Protein GZ082_RS12640 ENOG410689M (LipO)protein GZ082_RS12645 ENOG4107H52 Dicarboxylate transport GZ082_RS12650 ENOG4105C5I Dehydrogenase GZ082_RS12655 ENOG41090X5 Heat shock protein hslJ GZ082_RS12660 ENOG4105IKK cytoplasmic protein GZ082_RS12665 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) GZ082_RS12670 ENOG4105FCK Membrane GZ082_RS12675 ENOG4108RW8 Universal stress protein F GZ082_RS12685 ENOG4105DIK (ABC) transporter GZ082_RS12690 ENOG4105CC5 ABC transporter GZ082_RS12695 ENOG4105CC5 ABC transporter GZ082_RS12750 ENOG4108ES9 ParB domain protein nuclease GZ082_RS12755 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) GZ082_RS12765 ENOG4105KUS lysozyme GZ082_RS12770 ENOG4105QFS Lysis protein S homolog from lambdoid prophage GZ082_RS12790 ENOG4105RWQ Protein of unknown function (DUF1364) GZ082_RS12805 ENOG4105WPN DNA integration recombination invertion protein GZ082_RS12825 ENOG4105JBR DNA replication protein GZ082_RS12830 ENOG4105ZTP Protein of unknown function (DUF1376) GZ082_RS12870 ENOG4107C82 Rac prophage GZ082_RS12880 ENOG41076J9 exonuclease VIII GZ082_RS12885 ENOG4108PNI recT protein GZ082_RS12890 ENOG4106YAH restriction alleviation and modification enhancement GZ082_RS12895 ENOG41070YT Rac prophage GZ082_RS12900 ENOG4107160 Rac prophage GZ082_RS12905 ENOG4107R08 Integrase GZ082_RS12915 ENOG4105C1J atp-dependent rna helicase GZ082_RS12930 ENOG4105BZU Histidine kinase GZ082_RS12935 ENOG4108DG9 Smr protein MutS2 GZ082_RS12940 ENOG4106KR7 LysR family Transcriptional regulator GZ082_RS12945 ENOG4105CH2 amidohydrolase GZ082_RS12950 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B GZ082_RS12955 ENOG4105CFC Transporter GZ082_RS12960 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GZ082_RS12965 ENOG4105DS0 Transcriptional regulator, Crp Fnr family GZ082_RS12970 ENOG4105Q9Y Universal stress protein GZ082_RS12975 ENOG4105S5I Membrane GZ082_RS12980 ENOG4105D64 Mechanosensitive ion channel GZ082_RS12985 ENOG4107QSI ABC, transporter GZ082_RS12990 ENOG4105EQ2 LysR family Transcriptional regulator GZ082_RS12995 ENOG4105ENX hydrolase GZ082_RS13000 ENOG4105ENX hydrolase GZ082_RS13010 ENOG4105KXI murein peptide amidase A GZ082_RS13015 ENOG4107S8C mandelate racemase muconate lactonizing GZ082_RS13020 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) GZ082_RS13025 ENOG4108JU8 Transcriptional regulator GZ082_RS13035 ENOG4105CM6 amino acid regulated cytosolic protein GZ082_RS13040 ENOG4105FKQ transcriptional regulator GZ082_RS13045 ENOG4107EFV Outer membrane protein G GZ082_RS13050 ENOG4108IJ9 (ABC) transporter GZ082_RS13055 ENOG4107URF beta-phospho-glucomutase GZ082_RS13070 ENOG4107RRD Dehydrogenase GZ082_RS13075 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component GZ082_RS13080 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component GZ082_RS13085 ENOG4105WEM extracellular solute-binding protein GZ082_RS13090 ENOG4107QW3 Sucrose phosphorylase GZ082_RS13095 ENOG4105K8Z Phage shock protein GZ082_RS13100 ENOG4105NNG Peripheral inner membrane phage-shock protein GZ082_RS13105 ENOG4105FM1 phage shock protein C GZ082_RS13110 ENOG4105YYT phage shock protein B GZ082_RS13115 ENOG41087YS Phage shock protein A GZ082_RS13120 ENOG4105E51 psp operon transcriptional activator GZ082_RS13125 ENOG4108JPW Aminotransferase GZ082_RS13130 ENOG4105CJP fad dependent oxidoreductase GZ082_RS13135 ENOG4105C26 Dehydrogenase GZ082_RS13140 ENOG4107VRI Transcriptional regulator GZ082_RS13145 ENOG4108Z86 Glutamine amidotransferase GZ082_RS13150 ENOG4105CFQ glutamine synthetase GZ082_RS13160 ENOG4105CUB amino acid GZ082_RS13165 ENOG4105N0E Protein of unknown function (DUF2543) GZ082_RS13170 ENOG4108HIY periplasmic GZ082_RS13175 ENOG4108I5W peptide transport system, permease protein GZ082_RS13180 ENOG4108EU3 peptide transport system, permease GZ082_RS13185 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein GZ082_RS13190 ENOG4108JQ2 peptide transport system atp-binding protein GZ082_RS13195 ENOG4105WDY DNA (cytosine-5-)-methyltransferase GZ082_RS13200 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH GZ082_RS13205 ENOG4105Q4T oxidoreductase GZ082_RS13220 ENOG4105BZU Histidine kinase GZ082_RS13225 ENOG410643D UPF0509 protein GZ082_RS13230 ENOG4105N2W Transcriptional regulator GZ082_RS13240 ENOG4108ZJT translation initiation factor, Sui1 GZ082_RS13250 ENOG4105CFV Tetratricopeptide repeat protein GZ082_RS13255 ENOG4105Q4A inner membrane protein yciS GZ082_RS13260 ENOG4105EYK Phosphatidylglycerophosphatase B GZ082_RS13270 ENOG4107QM5 aconitate hydratase GZ082_RS13290 ENOG4107R11 Transcriptional regulator GZ082_RS13295 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GZ082_RS13300 ENOG4105RKX Protein of unknown function (DUF2498) GZ082_RS13305 ENOG4105ERU peptidase GZ082_RS13310 ENOG4105UBK short-chain dehydrogenase reductase GZ082_RS13315 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase GZ082_RS13320 ENOG4105FE9 pseudouridine synthase GZ082_RS13325 ENOG4107RTD sua5 ycio yrdc ywlc family protein GZ082_RS13330 ENOG4105DB7 PHP domain protein GZ082_RS13340 ENOG4105CRQ synthase (Component I) GZ082_RS13345 ENOG4108EFP Anthranilate synthase component II GZ082_RS13350 ENOG4105DK0 Indole-3-glycerol phosphate synthase GZ082_RS13370 ENOG4108Z9Z response to DNA damage stimulus GZ082_RS13375 ENOG4108N8X transition metal ion binding GZ082_RS13380 ENOG4105EIF outer membrane protein W GZ082_RS13400 ENOG4105NAU thioesterase Superfamily protein GZ082_RS13405 ENOG410822N TonB family GZ082_RS13410 ENOG4105K9H YciI-like protein GZ082_RS13415 ENOG4107SVH Potassium channel protein GZ082_RS13435 ENOG4108JQ7 (ABC) transporter GZ082_RS13440 ENOG4105C3U ABC transporter GZ082_RS13445 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GZ082_RS13450 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GZ082_RS13455 ENOG4108J59 Extracellular solute-binding protein, family 5 GZ082_RS13465 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein GZ082_RS13470 ENOG4105C0A alcohol dehydrogenase GZ082_RS13480 ENOG4107104 thymidine kinase GZ082_RS13485 ENOG4108SAU DNA-binding protein H-ns GZ082_RS13490 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GZ082_RS13495 ENOG4105I93 response regulator GZ082_RS13500 ENOG4105D78 K07001 NTE family protein GZ082_RS13510 ENOG4105CIY formyltetrahydrofolate deformylase GZ082_RS13530 ENOG41076YT nitrate reductase, gamma subunit GZ082_RS13535 ENOG4105R3A Nitrate reductase GZ082_RS13540 ENOG4108IUE nitrate reductase beta subunit GZ082_RS13545 ENOG4105CRU nitrate reductase, alpha subunit GZ082_RS13550 ENOG4105DQQ Major facilitator superfamily MFS_1 GZ082_RS13555 ENOG4105BZU Histidine kinase GZ082_RS13560 ENOG4105WH1 Two component transcriptional regulator luxr family GZ082_RS13565 ENOG4105ID0 Putative invasin GZ082_RS13570 ENOG41090EX DsrE family GZ082_RS13575 ENOG4108NH8 Cation transport protein GZ082_RS13580 ENOG4105WS7 Cation transport regulator GZ082_RS13585 ENOG4105EWV Sodium calcium exchanger membrane region GZ082_RS13610 ENOG41063JG Transcriptional regulator GZ082_RS13615 ENOG4108YY7 Invasion gene expression up-regulator SirB GZ082_RS13620 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) GZ082_RS13645 ENOG4105C5T Phosphoribosyl pyrophosphate synthase GZ082_RS13650 ENOG4105CHH sulfate transporter GZ082_RS13655 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria GZ082_RS13665 ENOG4105C3G gtp-binding protein GZ082_RS13670 ENOG4105I1J Autotransporter GZ082_RS13675 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family GZ082_RS13680 ENOG4105CMT Dihydroxyacetone kinase GZ082_RS13685 ENOG4108UTZ Dihydroxyacetone kinase GZ082_RS13690 ENOG4105VDH Dihydroxyacetone kinase GZ082_RS13710 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) GZ082_RS13715 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division GZ082_RS13720 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GZ082_RS13730 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GZ082_RS13740 ENOG4105ED1 spovr family GZ082_RS13755 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) GZ082_RS13760 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) GZ082_RS13765 ENOG4105KT5 UmuD protein GZ082_RS13770 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells GZ082_RS13780 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase GZ082_RS13785 ENOG4105VNT transposase (IS4 family) protein GZ082_RS13795 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium GZ082_RS13800 ENOG4105S66 prophage protein GZ082_RS13810 ENOG4107QMS site-determining protein GZ082_RS13845 ENOG410658X GZ082_RS13865 ENOG4105BZU Histidine kinase GZ082_RS13870 ENOG410738I uncharacterized protein ymgC GZ082_RS13880 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB GZ082_RS13885 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component GZ082_RS13890 ENOG4105BZU Histidine kinase GZ082_RS13895 ENOG4108XDN Transcriptional regulator GZ082_RS13900 ENOG41064WM Uncharacterized protein YcgX GZ082_RS13915 ENOG4108HMX isocitrate dehydrogenase (NADP) GZ082_RS13920 ENOG4108R99 pseudouridine synthase GZ082_RS13940 ENOG4107QTF adenylosuccinate lyase GZ082_RS13945 ENOG4105XJC Two component transcriptional regulator (Winged helix family GZ082_RS13950 ENOG4105IFJ Histidine kinase GZ082_RS13955 ENOG4105EZE Cupin 4 family protein GZ082_RS13965 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GZ082_RS13975 ENOG4105D38 putrescine abc transporter GZ082_RS13980 ENOG4107RUE extracellular solute-binding protein family 1 GZ082_RS13995 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) GZ082_RS14005 ENOG4105D60 lipoprotein releasing system transmembrane protein GZ082_RS14010 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) GZ082_RS14015 ENOG4105D60 lipoprotein releasing system transmembrane protein GZ082_RS14020 ENOG4105IQC Inner membrane protein YcfT GZ082_RS14025 ENOG4108JA2 transcriptioN-repair coupling factor GZ082_RS14030 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GZ082_RS14035 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction GZ082_RS14040 ENOG4108IND Tetr family transcriptional regulator GZ082_RS14045 ENOG4107MBR 17 kDa surface antigen GZ082_RS14050 ENOG4105CEP NADH dehydrogenase GZ082_RS14070 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) GZ082_RS14075 ENOG41090DQ Lipoprotein GZ082_RS14080 ENOG4105K59 histidine triad (HIT) protein GZ082_RS14085 ENOG4105CNM Receptor GZ082_RS14090 ENOG4105CI1 PTS System GZ082_RS14095 ENOG4105F8V Hydrolase, tatD family GZ082_RS14100 ENOG4107QRG dna polymerase iii GZ082_RS14110 ENOG4105HHA aminodeoxychorismate lyase GZ082_RS14115 ENOG4105YAZ 4-amino-4-deoxychorismate lyase GZ082_RS14120 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GZ082_RS14125 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GZ082_RS14130 ENOG4105CHR reductase GZ082_RS14135 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase GZ082_RS14155 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein GZ082_RS14160 ENOG4108UHJ MAF-like protein GZ082_RS14165 ENOG4105EI2 Pseudouridine synthase GZ082_RS14170 ENOG4107QQB Ribonuclease E GZ082_RS14175 ENOG4105DTJ flagellar hook-associated protein GZ082_RS14180 ENOG4105E1Q flagellar hook-associated protein GZ082_RS14185 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj GZ082_RS14200 ENOG4105CGA flagellar basal-body rod protein FlgG GZ082_RS14205 ENOG4108KPB Flagellar basal-body rod protein FlgF GZ082_RS14210 ENOG4105BZE flagellar hook protein, FlgE GZ082_RS14215 ENOG4105W00 Flagellar hook capping protein GZ082_RS14220 ENOG4108ZC9 flagellar basal-body rod protein flgc GZ082_RS14225 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) GZ082_RS14230 ENOG4105CKS Flagella basal body P-ring formation protein flgA GZ082_RS14235 ENOG4105M9M anti-sigma28 factor FlgM GZ082_RS14240 ENOG4105QVD Flagella synthesis protein FlgN GZ082_RS14245 ENOG4105CJR Integral membrane protein (MviN GZ082_RS14250 ENOG4105EP9 oxidoreductase GZ082_RS14260 ENOG4105D9U N-acetyltransferase GZ082_RS14270 ENOG4105E9S glutaredoxin 2 GZ082_RS14275 ENOG4105F3T (LipO)protein GZ082_RS14285 ENOG4105MEA DNA damage-inducible protein i GZ082_RS14290 ENOG4105PVA Biofilm formation regulatory protein BssS GZ082_RS14300 ENOG4106974 biofilm formation GZ082_RS14305 ENOG4105DS1 cytochrome b561 GZ082_RS14310 ENOG4108YYC ycei family GZ082_RS14320 ENOG4105D1S lipid A biosynthesis GZ082_RS14330 ENOG4108W47 Acidic protein msyB GZ082_RS14335 ENOG4105NAC (LipO)protein GZ082_RS14340 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) GZ082_RS14355 ENOG4107RZC phospholipase d GZ082_RS14360 ENOG4108UVJ appr-1-p processing domain protein GZ082_RS14375 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin GZ082_RS14380 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers GZ082_RS14385 ENOG41086KC Transcriptional regulator GZ082_RS14390 ENOG4108XDW curli assembly protein CsgE GZ082_RS14395 ENOG4108WYR Curli production assembly transport component, CsgF GZ082_RS14400 ENOG4105P8Q Curli production assembly transport component CsgG GZ082_RS14405 ENOG4108UQ5 membrane protein YcdZ GZ082_RS14410 ENOG4107XHZ cytoplasmic chaperone TorD family protein GZ082_RS14420 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase GZ082_RS14435 ENOG4108T85 Membrane GZ082_RS14450 ENOG4105BZU Histidine kinase GZ082_RS14455 ENOG4108TUY outer membrane protein PgaA GZ082_RS14460 ENOG4107BJW polysaccharide deacetylase GZ082_RS14465 ENOG4105CND Glycosyl transferase, family 2 GZ082_RS14475 ENOG4105D5M phosphate starvation-inducible protein GZ082_RS14480 ENOG4105DBE peroxidase GZ082_RS14485 ENOG410650H (LipO)protein GZ082_RS14495 ENOG4105CK7 Sodium proline symporter GZ082_RS14505 ENOG4105C26 Dehydrogenase GZ082_RS14510 ENOG4108R86 Transcriptional regulator GZ082_RS14530 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) GZ082_RS14545 ENOG4105C2W permease GZ082_RS14550 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 GZ082_RS14560 ENOG4105XH3 GZ082_RS14565 ENOG4105D6F Phosphatase GZ082_RS14590 ENOG4108J2R molybdopterin oxidoreductase GZ082_RS14595 ENOG4105CUW cytochrome C-TYPE protein GZ082_RS14600 ENOG4106WF9 DNA-binding transcriptional regulator TorR GZ082_RS14605 ENOG4108SV3 Tmao reductase system periplasmic protein tort GZ082_RS14615 ENOG4105HEE Binding Domain protein GZ082_RS14620 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation GZ082_RS14635 ENOG4105VEQ Cold shock protein GZ082_RS14640 ENOG41060EU Cold shock-like protein GZ082_RS14650 ENOG4108Y9B (LipO)protein GZ082_RS14655 ENOG4108W78 Pfam:DUF1017 GZ082_RS14660 ENOG4105E3R (LipO)protein GZ082_RS14665 ENOG4105DAY polysaccharide export protein GZ082_RS14670 ENOG4107ZF2 Phosphatase GZ082_RS14675 ENOG4105D75 Capsular exopolysaccharide family GZ082_RS14680 ENOG4105D6F Phosphatase GZ082_RS14690 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GZ082_RS14695 ENOG4105C4M (Ubiquinol oxidase) subunit I GZ082_RS14700 ENOG4105MVP hydrogenase-1 operon protein HyaF GZ082_RS14705 ENOG4108VXY Hydrogenase-1 operon protein HyaE GZ082_RS14710 ENOG4108USZ hydrogenase GZ082_RS14715 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit GZ082_RS14720 ENOG4105DPX Hydrogenase, large subunit GZ082_RS14725 ENOG4105E3S small subunit GZ082_RS14735 ENOG4108MN8 Membrane GZ082_RS14740 ENOG4108Z0T Part of a sulfur-relay system (By similarity) GZ082_RS14745 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 GZ082_RS14760 ENOG4105K4P CoA-binding domain protein GZ082_RS14775 ENOG41088T4 Helicase IV GZ082_RS14780 ENOG410901E Membrane GZ082_RS14785 ENOG4105EM2 membrane GZ082_RS14790 ENOG4108RZ1 DNA transformation protein GZ082_RS14800 ENOG4105UYK outer membrane protein a GZ082_RS14810 ENOG4105DAN ATP-dependent protease GZ082_RS14820 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) GZ082_RS14825 ENOG4108Q2G (LipO)protein GZ082_RS14830 ENOG4105DY2 Paraquat-inducible protein b GZ082_RS14835 ENOG4105F1S paraquat-inducible protein a GZ082_RS14840 ENOG4105C5H ABC transporter GZ082_RS14850 ENOG4105QVC MOSC domain-containing protein GZ082_RS14855 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) GZ082_RS14865 ENOG4106PH7 chaperone GZ082_RS14870 ENOG4105MX3 Fimbrial GZ082_RS14875 ENOG4105Q7J Fimbrial GZ082_RS14880 ENOG4108MDY Fimbrial GZ082_RS14885 ENOG4105CW0 outer membrane usher protein GZ082_RS14890 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae GZ082_RS14895 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon GZ082_RS14900 ENOG4108UZX fmn reductase GZ082_RS14905 ENOG4105GVF (ABC) transporter GZ082_RS14915 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component GZ082_RS14925 ENOG4105CD8 aminopeptidase N GZ082_RS14940 ENOG4105FCK Membrane GZ082_RS14945 ENOG4105CGF Aromatic amino acid aminotransferase GZ082_RS14950 ENOG4105C5X domain protein GZ082_RS14955 ENOG4105EAQ (twin-arginine translocation) pathway signal GZ082_RS14960 ENOG4105DIT ErfK YbiS YcfS YnhG family protein GZ082_RS14970 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) GZ082_RS14980 ENOG4106371 Methyltransferase GZ082_RS14985 ENOG4107S90 membrAne GZ082_RS14990 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups GZ082_RS15005 ENOG4105T0Z Conserved Protein GZ082_RS15015 ENOG4105BZ1 (ABC) transporter GZ082_RS15020 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 GZ082_RS15030 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) GZ082_RS15040 ENOG4108K0D peptidase, M48 GZ082_RS15045 ENOG4105VNT transposase (IS4 family) protein GZ082_RS15060 ENOG4107VMU Membrane GZ082_RS15065 ENOG4105DDY UPF0142 protein ycaO GZ082_RS15070 ENOG4105TMB Formate nitrite transporter GZ082_RS15075 ENOG4105C6N Formate acetyltransferase GZ082_RS15080 ENOG4105F1A Pyruvate formate-lyase GZ082_RS15085 ENOG4108X0B nad(p)h dehydrogenase (quinone) GZ082_RS15090 ENOG410642W LysR family Transcriptional regulator GZ082_RS15095 ENOG4105E5D amino acid GZ082_RS15105 ENOG4105CHJ isochorismatase hydrolase GZ082_RS15110 ENOG4107KGK dmso reductase anchor subunit GZ082_RS15115 ENOG4105QAX Iron-sulfur GZ082_RS15120 ENOG4107QY8 reductase GZ082_RS15130 ENOG4105D1H recombination factor protein RarA GZ082_RS15140 ENOG4105CNU cell division protein FtsK GZ082_RS15150 ENOG4105C3M thioredoxin reductase GZ082_RS15155 ENOG4108JJ9 ABC, transporter GZ082_RS15160 ENOG4108JJ8 (ABC) transporter GZ082_RS15170 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) GZ082_RS15180 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GZ082_RS15190 ENOG4105VEQ Cold shock protein GZ082_RS15195 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GZ082_RS15200 ENOG4105DJY efflux transporter, rnd family, mfp subunit GZ082_RS15205 ENOG4108MJ5 VirK protein GZ082_RS15210 ENOG4105CPB ATP-dependent endonuclease of the OLD family GZ082_RS15215 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GZ082_RS15220 ENOG4105DWU Membrane GZ082_RS15230 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GZ082_RS15235 ENOG4105C7K acetolactate synthase GZ082_RS15240 ENOG4105C5W Aldolase GZ082_RS15245 ENOG4105CGD Nad-dependent epimerase dehydratase GZ082_RS15250 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase GZ082_RS15255 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase GZ082_RS15265 ENOG41064MM (LipO)protein GZ082_RS15270 ENOG4105E5Z arginine transporter ATP-binding subunit GZ082_RS15275 ENOG4106PMH Extracellular solute-binding protein family 3 GZ082_RS15280 ENOG4105GBT ABC transporter GZ082_RS15285 ENOG4105DMR ABC, transporter GZ082_RS15290 ENOG4106TNF Periplasmic binding protein GZ082_RS15300 ENOG4105RBQ inner membrane protein ybjO GZ082_RS15305 ENOG4105D38 putrescine abc transporter GZ082_RS15310 ENOG4105F38 ABC transporter, permease GZ082_RS15315 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GZ082_RS15320 ENOG4107RUE extracellular solute-binding protein family 1 GZ082_RS15325 ENOG4108RMJ sensory transduction regulator GZ082_RS15335 ENOG4108DBC nitroreductase GZ082_RS15340 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress GZ082_RS15345 ENOG41090BQ Glutaredoxin GZ082_RS15350 ENOG4105GWF inner membrane protein YbjM GZ082_RS15360 ENOG4105ZTC transcriptional activator, Ogr delta GZ082_RS15400 ENOG4108C33 Resolvase GZ082_RS15405 ENOG4105PTU response to oxidative stress GZ082_RS15410 ENOG4108US3 tail fiber assembly GZ082_RS15500 ENOG4105ED4 portal protein GZ082_RS15530 ENOG4105VZ1 Replication Protein GZ082_RS15540 ENOG4105DFE Dna adenine methylase GZ082_RS15545 ENOG4105KSC Transcriptional regulator, TraR DksA family GZ082_RS15570 ENOG4105MEH GZ082_RS15585 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GZ082_RS15595 ENOG4108RFG Tetr family transcriptional regulator GZ082_RS15600 ENOG4106UW1 Major Facilitator superfamily GZ082_RS15605 ENOG4108HCJ Hydrolase GZ082_RS15615 ENOG4107QF7 multi-drug GZ082_RS15620 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase GZ082_RS15625 ENOG4107FB0 transcriptional regulator DeoR family GZ082_RS15630 ENOG4105DZ1 carboxypeptidase GZ082_RS15635 ENOG4108TGY Glutathione S-transferase GZ082_RS15640 ENOG4105D8V Glucose sorbosone dehydrogenase GZ082_RS15645 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway GZ082_RS15655 ENOG41064RH membrane protein YliF GZ082_RS15660 ENOG4105BZU Histidine kinase GZ082_RS15685 ENOG4105D44 asparaginase GZ082_RS15690 ENOG4105CVM Molybdenum cofactor synthesis domain protein GZ082_RS15695 ENOG4105D06 uba thif-type nad fad binding protein GZ082_RS15700 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GZ082_RS15705 ENOG4105F1A Pyruvate formate-lyase GZ082_RS15715 ENOG4108HCJ Hydrolase GZ082_RS15720 ENOG41072TH Protein of unknown function (DUF1479) GZ082_RS15730 ENOG4105C5H ABC transporter GZ082_RS15735 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein GZ082_RS15740 ENOG4105F4P )-transporter GZ082_RS15745 ENOG4105KST dependent repressor GZ082_RS15755 ENOG4108I6E Sulfatase GZ082_RS15760 ENOG4108T1M outer membrane protein x GZ082_RS15770 ENOG4107AQZ Membrane GZ082_RS15780 ENOG4107R0W ABC transporter GZ082_RS15785 ENOG4105E5Q amino acid AbC transporter GZ082_RS15790 ENOG4105CDA abc transporter atp-binding protein GZ082_RS15795 ENOG4105D8X mechanosensitive ion channel GZ082_RS15805 ENOG4105ZY9 UPF0379 protein ybiM GZ082_RS15810 ENOG4108IU3 tonb-dependent siderophore receptor GZ082_RS15815 ENOG4105VNT transposase (IS4 family) protein GZ082_RS15830 ENOG4105KSC Transcriptional regulator, TraR DksA family GZ082_RS15835 ENOG4105VR4 UPF0379 protein ybiJ GZ082_RS15845 ENOG4105DG4 malate L-lactate dehydrogenase GZ082_RS15850 ENOG4108MTB glycosyl transferase family GZ082_RS15855 ENOG4105DVT helicase GZ082_RS15865 ENOG4105C1J atp-dependent rna helicase GZ082_RS15870 ENOG4107MVR Transcriptional regulator GZ082_RS15880 ENOG4105CJ1 ABC, transporter GZ082_RS15885 ENOG4107QWP ABC-2 type transporter GZ082_RS15890 ENOG4107QWP ABC-2 type transporter GZ082_RS15895 ENOG4105I9U inner membrane protein ybhQ GZ082_RS15900 ENOG4105X23 Endonuclease Exonuclease phosphatase GZ082_RS15905 ENOG4105DZQ phospholipase D Transphosphatidylase GZ082_RS15910 ENOG4107UXM Membrane GZ082_RS15915 ENOG410733J conserved inner membrane protein GZ082_RS15920 ENOG4105HFZ Membrane GZ082_RS15925 ENOG4108ZAF Molybdopterin GZ082_RS15930 ENOG4105M00 molybdopterin converting factor, subunit 1 GZ082_RS15940 ENOG4108RIR Molybdenum cofactor biosynthesis protein GZ082_RS15950 ENOG4105CHW UPF0052 protein GZ082_RS15960 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GZ082_RS15965 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GZ082_RS15980 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) GZ082_RS15985 ENOG4108V1U phospholipid-binding protein GZ082_RS15990 ENOG4105NBR Pectinesterase GZ082_RS15995 ENOG4107QM5 aconitate hydratase GZ082_RS16000 ENOG4107QPK )-transporter GZ082_RS16005 ENOG4105C7F AcnD-accessory protein PrpF GZ082_RS16010 ENOG4105F04 LysR family Transcriptional regulator GZ082_RS16020 ENOG4108K4B hydrolase GZ082_RS16030 ENOG4105E0C molybdate abc transporter GZ082_RS16035 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein GZ082_RS16045 ENOG4105F4R Transcriptional regulator mode GZ082_RS16050 ENOG4105DKW ABC transporter GZ082_RS16055 ENOG4105CMR udp-glucose 4-epimerase GZ082_RS16060 ENOG4105F0Z galactose-1-phosphate uridylyltransferase GZ082_RS16070 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) GZ082_RS16080 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GZ082_RS16085 ENOG4105JND homeobox protein GZ082_RS16090 ENOG4105PGM cation diffusion facilitator family transporter GZ082_RS16095 ENOG4106Z1T Nicotinamide Mononucleotide Transporter GZ082_RS16145 ENOG4105UFD tol-pal system protein YbgF GZ082_RS16150 ENOG4105KCK Peptidoglycan-associated lipoprotein GZ082_RS16160 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA GZ082_RS16170 ENOG4105E02 MotA TolQ exbB proton channel GZ082_RS16175 ENOG4107YD3 Thioesterase GZ082_RS16180 ENOG4105KJB cyd operon protein YbgE GZ082_RS16190 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GZ082_RS16195 ENOG4105C4M (Ubiquinol oxidase) subunit I GZ082_RS16200 ENOG4105C8I hydrolase, family 38 GZ082_RS16205 ENOG4105DM4 PTS System GZ082_RS16210 ENOG4105FDP GntR family transcriptional regulator GZ082_RS16215 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha GZ082_RS16225 ENOG4105C7S Dehydrogenase GZ082_RS16230 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 GZ082_RS16235 ENOG4105E33 succinate dehydrogenase GZ082_RS16240 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GZ082_RS16245 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein GZ082_RS16250 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit GZ082_RS16260 ENOG4105BZN citrate synthase GZ082_RS16265 ENOG4106UBK fimbrial-like adhesin protein GZ082_RS16270 ENOG4106PG1 outer membrane usher protein GZ082_RS16275 ENOG4108TTM chaperone GZ082_RS16280 ENOG4108MY7 Fimbrial GZ082_RS16285 ENOG4108KK1 membrane protein AbrB duplication GZ082_RS16300 ENOG4107R7A Allophanate hydrolase subunit 2 GZ082_RS16305 ENOG4105P4J Allophanate hydrolase, subunit 1 GZ082_RS16310 ENOG4107QNR UPF0135 protein GZ082_RS16315 ENOG4105DUX Transporter GZ082_RS16320 ENOG4105CVP deoxyribo-dipyrimidine photolyase GZ082_RS16325 ENOG4107SEY Conserved Protein GZ082_RS16340 ENOG4106R09 GZ082_RS16345 ENOG4105CNA YD repeat protein GZ082_RS16350 ENOG41079JQ Membrane GZ082_RS16355 ENOG4105CNA YD repeat protein GZ082_RS16360 ENOG4105XIQ Protein of unknown function (DUF2517) GZ082_RS16385 ENOG4105C08 Histidine kinase GZ082_RS16390 ENOG4105EEX Two component transcriptional regulator (Winged helix family GZ082_RS16400 ENOG4105CXN decarboxylase GZ082_RS16405 ENOG4105D5Q Arginine ornithine antiporter GZ082_RS16410 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 GZ082_RS16415 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) GZ082_RS16420 ENOG4105EV9 Alpha Beta Hydrolase GZ082_RS16425 ENOG4105NNH LexA regulated protein GZ082_RS16430 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) GZ082_RS16440 ENOG41090R7 Ferric uptake GZ082_RS16445 ENOG4105GX6 (LipO)protein GZ082_RS16460 ENOG4105CI1 PTS System GZ082_RS16470 ENOG4105CE4 GlcNAc 6-P deacetylase GZ082_RS16475 ENOG4105E2R ROK family GZ082_RS16480 ENOG4105D4U had-superfamily hydrolase, subfamily iia GZ082_RS16485 ENOG4105CAQ asparagine synthetase GZ082_RS16525 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family GZ082_RS16535 ENOG4105C9A Phoh family GZ082_RS16545 ENOG4108JU5 Magnesium and cobalt efflux protein GZ082_RS16550 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) GZ082_RS16555 ENOG4107U91 Rhomboid family GZ082_RS16560 ENOG4107RP9 extracellular solute-binding protein, family 3 GZ082_RS16565 ENOG4105EAD ABC transporter GZ082_RS16570 ENOG4105DRP amino acid AbC transporter GZ082_RS16575 ENOG4105CDA abc transporter atp-binding protein GZ082_RS16585 ENOG4105F7F Chaperone GZ082_RS16590 ENOG4105QFC Hsc56 co-chaperone of HscC GZ082_RS16595 ENOG41069CF Protein of unknown function (DUF1266) GZ082_RS16600 ENOG4107JFD Sel1 repeat GZ082_RS16605 ENOG4105QFC Hsc56 co-chaperone of HscC GZ082_RS16610 ENOG41069CF Protein of unknown function (DUF1266) GZ082_RS16615 ENOG4105EUU Sel1 domain protein repeat-containing protein GZ082_RS16620 ENOG4107PAI alpha helical protein GZ082_RS16635 ENOG4105DJF DNA polymerase III, delta' subunit GZ082_RS16645 ENOG4108TGR phosphatase GZ082_RS16650 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) GZ082_RS16660 ENOG4105CJN penicillin-binding protein GZ082_RS16665 ENOG4105CNI cell division protein FtsW GZ082_RS16670 ENOG4105K6T rare lipoprotein A GZ082_RS16675 ENOG4105DZ1 carboxypeptidase GZ082_RS16690 ENOG41064T2 transcriptional regulator, lysR family GZ082_RS16700 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) GZ082_RS16720 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) GZ082_RS16725 ENOG4105CEE C4-dicarboxylate transporter GZ082_RS16730 ENOG4106YYS transcriptional regulatory protein GZ082_RS16735 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism GZ082_RS16740 ENOG4105DUA (citrate (pro-3S)-lyase ligase GZ082_RS16750 ENOG4105CI0 Citrate lyase GZ082_RS16755 ENOG4105CHY citrate lyase, alpha GZ082_RS16770 ENOG4107QPK )-transporter GZ082_RS16775 ENOG4105KTS ribonuclease GZ082_RS16780 ENOG4105NXH GreA GreB family elongation factor GZ082_RS16785 ENOG4105E2A Dehydrogenase GZ082_RS16790 ENOG4108U51 Universal stress protein GZ082_RS16795 ENOG4108JU3 Alkyl hydroperoxide reductase GZ082_RS16800 ENOG4105D3R alkyl hydroperoxide reductase GZ082_RS16805 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase GZ082_RS16810 ENOG4105DQS Transcriptional regulator GZ082_RS16815 ENOG4105BZV Phosphoadenosine phosphosulfate reductase GZ082_RS16820 ENOG4105GTN ParB Domain Protein Nuclease GZ082_RS16825 ENOG4105CHM Aminotransferase GZ082_RS16830 ENOG4107SCQ Iron-containing alcohol dehydrogenase GZ082_RS16835 ENOG4105VCD cytoplasmic protein GZ082_RS16840 ENOG4105D22 carbon starvation protein GZ082_RS16845 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) GZ082_RS16850 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase GZ082_RS16855 ENOG4105WQI isochorismatase GZ082_RS16860 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase GZ082_RS16865 ENOG4105E4F Isochorismate synthase GZ082_RS16870 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein GZ082_RS16880 ENOG4105DQ5 transport system permease protein GZ082_RS16885 ENOG4105TVJ transport system, permease GZ082_RS16890 ENOG4105E0A ABC, transporter GZ082_RS16895 ENOG4108QY5 Ferric enterobactin transport protein GZ082_RS16900 ENOG4105C0W non-ribosomal peptide synthetase GZ082_RS16905 ENOG41085A6 mbth domain-containing protein GZ082_RS16910 ENOG4105E93 esterase GZ082_RS16915 ENOG4107RNH Outer membrane receptor FepA GZ082_RS16920 ENOG4108TSE Transferase GZ082_RS16930 ENOG4107635 Hok Gef family protein GZ082_RS16940 ENOG4105WQ6 Membrane GZ082_RS16945 ENOG4105MSB protein, conserved in bacteria GZ082_RS16950 ENOG4108RCM Nitroreductase GZ082_RS16955 ENOG4105CUY Mechanosensitive ion channel GZ082_RS16960 ENOG4105C85 amino acid GZ082_RS16965 ENOG4108IJF Heavy metal efflux pump, CzcA GZ082_RS16970 ENOG4105EP1 Efflux transporter rnd family, mfp subunit GZ082_RS16975 ENOG410624V efflux system protein GZ082_RS16980 ENOG4105ENJ RND efflux system, outer membrane lipoprotein GZ082_RS16985 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GZ082_RS16990 ENOG4105GR3 Histidine kinase GZ082_RS16995 ENOG4105CS6 Rhs element vgr protein GZ082_RS17020 ENOG4108WF3 methyltransferase GZ082_RS17025 ENOG4105UZW Tail fiber assembly protein GZ082_RS17040 ENOG4107DE1 head-to-tail joining protein GZ082_RS17045 ENOG4105UZW Tail fiber assembly protein GZ082_RS17050 ENOG4105FKG DNA packaging protein GZ082_RS17055 ENOG4106YSC GZ082_RS17070 ENOG4105QYK bacteriophage lambda Bor protein homolog GZ082_RS17080 ENOG4105KUS lysozyme GZ082_RS17085 ENOG4105QFS Lysis protein S homolog from lambdoid prophage GZ082_RS17095 ENOG4105HRS Antitermination protein GZ082_RS17115 ENOG4105H40 GZ082_RS17120 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) GZ082_RS17125 ENOG4108R7K Metal Dependent Phosphohydrolase GZ082_RS17130 ENOG41077V0 CPS-53 (KpLE1) prophage GZ082_RS17140 ENOG4108KU3 Integrase GZ082_RS17150 ENOG4108Q9V regulatoR GZ082_RS17155 ENOG4108ZI2 Fimbrial protein GZ082_RS17160 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) GZ082_RS17170 ENOG4108AF8 Chaperone GZ082_RS17175 ENOG4108WDE Fimbrial protein GZ082_RS17185 ENOG4105WQ3 Rna-binding protein GZ082_RS17190 ENOG4105S2T inner membrane protein YbcI GZ082_RS17200 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) GZ082_RS17210 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) GZ082_RS17215 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit GZ082_RS17220 ENOG4105C5B carbamate kinase GZ082_RS17225 ENOG4105G5A Protein of unknown function (DUF2877) GZ082_RS17230 ENOG4107REC cytoplasmic protein GZ082_RS17235 ENOG4107R1Q Membrane protein FdrA GZ082_RS17240 ENOG4105DG4 malate L-lactate dehydrogenase GZ082_RS17245 ENOG4105CE7 Amidase, hydantoinase carbamoylase family GZ082_RS17250 ENOG4105S0E allantoin catabolism protein GZ082_RS17255 ENOG4105BZW Glycerate kinase GZ082_RS17260 ENOG4105DTE Xanthine uracil vitamin C permease GZ082_RS17270 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease GZ082_RS17275 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GZ082_RS17280 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) GZ082_RS17285 ENOG41060W2 glyoxylate carboligase GZ082_RS17290 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region GZ082_RS17300 ENOG4107653 Transcriptional regulator GZ082_RS17320 ENOG4105CNA YD repeat protein GZ082_RS17325 ENOG4105CV6 ABC transporter, permease GZ082_RS17330 ENOG4108I0Y (ABC) transporter GZ082_RS17335 ENOG4108UJV acyl-CoA thioesterase i GZ082_RS17340 ENOG4105E1F short-chain dehydrogenase reductase GZ082_RS17345 ENOG4107QR8 Thioredoxin GZ082_RS17350 ENOG4105C4B ABC transporter, permease GZ082_RS17355 ENOG41083J0 (ABC) transporter GZ082_RS17360 ENOG4107QX8 SPFH domain, Band 7 family protein GZ082_RS17365 ENOG4105G5H Membrane GZ082_RS17370 ENOG4108Z6Z Transcriptional regulator GZ082_RS17375 ENOG4107RY6 amino acid GZ082_RS17380 ENOG4105CSV Glutaminase GZ082_RS17385 ENOG4105C59 p-type ATPase GZ082_RS17390 ENOG41081XE plasmid maintenance system antidote protein, xre family GZ082_RS17395 ENOG4105MBR gumn family GZ082_RS17400 ENOG4108Z66 YbaK ebsC protein GZ082_RS17405 ENOG4105CGH 5'-nucleotidase GZ082_RS17410 ENOG4105EU0 Major facilitator Superfamily GZ082_RS17415 ENOG4105CKD glutathione-regulated potassium-efflux system protein GZ082_RS17420 ENOG4107RE1 Inosine-guanosine kinase GZ082_RS17455 ENOG4107QMP dna polymerase iii subunits gamma and tau GZ082_RS17465 ENOG4105WD1 Membrane GZ082_RS17470 ENOG4108URS primosomal replication protein n'' GZ082_RS17475 ENOG4106428 Protein of unknown function (DUF2496) GZ082_RS17480 ENOG4105EGS Mechanosensitive ion channel GZ082_RS17485 ENOG4107XI7 Tetr family transcriptional regulator GZ082_RS17490 ENOG4105C1P efflux transporter, rnd family, mfp subunit GZ082_RS17495 ENOG4105BZS acriflavin resistance protein GZ082_RS17500 ENOG4108UKR Biofilm formation regulator YbaJ GZ082_RS17505 ENOG4105KF5 hemolysin expression-modulating protein GZ082_RS17510 ENOG4108UW5 maltose o-acetyltransferase GZ082_RS17515 ENOG4105GSJ Inner membrane protein ylaC GZ082_RS17520 ENOG41066DG (EAL) domain protein GZ082_RS17525 ENOG4105KCV RNA signal recognition particle 4.5S RNA GZ082_RS17535 ENOG41080UX Methyltransferase GZ082_RS17540 ENOG4108MNP Glycoprotein polysaccharide metabolism GZ082_RS17545 ENOG4105C29 acyl-CoA thioesterase GZ082_RS17550 ENOG4105BZU Histidine kinase GZ082_RS17555 ENOG4108YZA Nitrogen regulatory protein pii GZ082_RS17560 ENOG4105BZ1 (ABC) transporter GZ082_RS17565 ENOG4105BZ1 (ABC) transporter GZ082_RS17570 ENOG4108XM1 transcriptional regulator AsnC family GZ082_RS17580 ENOG4108NFA extracellular solute-binding protein GZ082_RS17590 ENOG4108TGP Thioesterase superfamily protein GZ082_RS17595 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein GZ082_RS17600 ENOG4105EIN peptidylprolyl cis-trans isomerase GZ082_RS17605 ENOG4105K70 DNA-binding protein GZ082_RS17610 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) GZ082_RS17630 ENOG4105M85 Bola protein GZ082_RS17635 ENOG4105IEY (LipO)protein GZ082_RS17640 ENOG4105EYM Major Facilitator superfamily GZ082_RS17645 ENOG4105E2S oxidase) subunit II GZ082_RS17650 ENOG4105BZ9 Cytochrome C oxidase, subunit I GZ082_RS17655 ENOG4105CCU oxidase (Subunit III) GZ082_RS17660 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) GZ082_RS17685 ENOG4107RDB Major Facilitator GZ082_RS17695 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) GZ082_RS17700 ENOG4107S0N DJ-1 family GZ082_RS17715 ENOG4105CTB Polyprenyl synthetase GZ082_RS17725 ENOG4105CPC Aldo Keto reductase GZ082_RS17730 ENOG4108ZAI phosphatidylglycerophosphatase a GZ082_RS17735 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) GZ082_RS17745 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) GZ082_RS17750 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) GZ082_RS17760 ENOG4108KIC (LipO)protein GZ082_RS17765 ENOG4105DRB nucleoside-specific channel-forming protein GZ082_RS17770 ENOG4105N1F Hnh endonuclease GZ082_RS17775 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GZ082_RS17780 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GZ082_RS17785 ENOG4105VIE preprotein translocase, subunit YajC GZ082_RS17805 ENOG4107R28 alpha amylase, catalytic region GZ082_RS17810 ENOG4105C85 amino acid GZ082_RS17815 ENOG4105CWM branched-chain amino acid transport system II carrier protein GZ082_RS17820 ENOG4105BZU Histidine kinase GZ082_RS17825 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GZ082_RS17830 ENOG4107RH8 nuclease SbcCD subunit D GZ082_RS17835 ENOG4105EYH Exonuclease GZ082_RS17840 ENOG4105F27 Major Facilitator GZ082_RS17845 ENOG4105DKQ ROK family GZ082_RS17865 ENOG4105HBA AroM protein GZ082_RS17870 ENOG4105SS3 GZ082_RS17885 ENOG4105II7 pyrroline-5-carboxylate reductase GZ082_RS17890 ENOG4105BZU Histidine kinase GZ082_RS17895 ENOG4105VIF phosphate starvation-inducible protein GZ082_RS17900 ENOG4105G6Z alkaline phosphatase GZ082_RS17915 ENOG4105CPF Cell wall formation (By similarity) GZ082_RS17920 ENOG4105UNH Membrane GZ082_RS17925 ENOG4105FR5 inner membrane protein YaiY GZ082_RS17930 ENOG4107QS8 (LipO)protein GZ082_RS17935 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 GZ082_RS17940 ENOG4107R6D beta-lactam binding protein AmpH GZ082_RS17945 ENOG4108PNB DNA-binding transcriptional regulator GZ082_RS17955 ENOG4105D52 delta-aminolevulinic acid dehydratase GZ082_RS17960 ENOG4105E2B Taurine dioxygenase GZ082_RS17965 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component GZ082_RS17975 ENOG4106FTQ Taurine ABC transporter, periplasmic GZ082_RS17980 ENOG4107W19 lmbE family GZ082_RS17985 ENOG4108PBI Polysaccharide metabolism GZ082_RS17995 ENOG4105SRB Uncharacterized protein yaiO GZ082_RS18015 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme GZ082_RS18020 ENOG4108SC4 )-transporter GZ082_RS18055 ENOG4108K2P TRANSCRIPTIONal GZ082_RS18060 ENOG4105ETE Transcriptional regulator (LacI family GZ082_RS18070 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) GZ082_RS18075 ENOG4108UW5 maltose o-acetyltransferase GZ082_RS18080 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GZ082_RS18085 ENOG4105DXD 2-methylcitrate dehydratase GZ082_RS18090 ENOG4105BZN citrate synthase GZ082_RS18095 ENOG4105CR4 methylisocitrate lyase GZ082_RS18100 ENOG4108JU7 Transcriptional regulator GZ082_RS18105 ENOG4105TDT uncharacterized protein yahO GZ082_RS18110 ENOG4105E82 cytochrome subunit of dehydrogenase GZ082_RS18125 ENOG4105DQ4 alcohol dehydrogenase GZ082_RS18130 ENOG4105CNN ABC, transporter GZ082_RS18135 ENOG4105CNN ABC, transporter GZ082_RS18140 ENOG4105C2J ABC transporter GZ082_RS18145 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GZ082_RS18155 ENOG4105DZC cytosine deaminase GZ082_RS18160 ENOG4105C5B carbamate kinase GZ082_RS18165 ENOG4107REC cytoplasmic protein GZ082_RS18170 ENOG4107R1Q Membrane protein FdrA GZ082_RS18175 ENOG4105N16 Protein of unknown function (DUF2877) GZ082_RS18180 ENOG4107SNB ankyrin repeat protein YahD GZ082_RS18185 ENOG4105SZ2 membrAne GZ082_RS18190 ENOG4108NUU Transcriptional regulator GZ082_RS18195 ENOG4105BZU Histidine kinase GZ082_RS18205 ENOG4105C94 Transporter GZ082_RS18230 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) GZ082_RS18235 ENOG4107QR9 Iron-sulfur cluster binding protein GZ082_RS18240 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GZ082_RS18245 ENOG4108K01 transcriptional regulator GZ082_RS18250 ENOG4107QN2 dihydrolipoyl dehydrogenase GZ082_RS18255 ENOG41066GK UPF0379 protein ykgI GZ082_RS18260 ENOG4108KBJ Inner membrane protein YkgB GZ082_RS18265 ENOG4105CV8 reductase GZ082_RS18305 ENOG4108GWT fimbrillin MatB GZ082_RS18315 ENOG4108N3D putative enzyme GZ082_RS18320 ENOG4106PYX Receptor GZ082_RS18325 ENOG4108UD7 cell wall organization GZ082_RS18330 ENOG4105PI0 Ferredoxin GZ082_RS18335 ENOG4105R3P Inner membrane protein yagU GZ082_RS18340 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit GZ082_RS18345 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding GZ082_RS18350 ENOG4105C7W Xanthine dehydrogenase GZ082_RS18355 ENOG4107XAN XdhC and CoxI family GZ082_RS18440 ENOG4105DFP Integrase GZ082_RS18460 ENOG4105FCK Membrane GZ082_RS18480 ENOG4105CIN aminoacyl-histidine dipeptidase GZ082_RS18485 ENOG4108S2Y peptide Chain Release factor GZ082_RS18495 ENOG4108HYG acetyltransferase GZ082_RS18525 ENOG4108YS0 lipoprotein YafL GZ082_RS18535 ENOG4105VXN addiction module toxin, RelE StbE family GZ082_RS18540 ENOG4105F7V ErfK ybiS ycfS ynhG family protein GZ082_RS18545 ENOG4105E7A Glutamine amidotransferase GZ082_RS18555 ENOG4107QPN acyl-Coa dehydrogenase GZ082_RS18560 ENOG4108WN0 inhibitor of vertebrate lysozyme GZ082_RS18565 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase GZ082_RS18590 ENOG4105CNA YD repeat protein GZ082_RS18625 ENOG4105CS6 Rhs element vgr protein GZ082_RS18630 ENOG4108WC9 type VI secretion system effector, hcp1 family GZ082_RS18670 ENOG4105GMB type VI secretion system effector, hcp1 family GZ082_RS18685 ENOG410600K aminopeptidase GZ082_RS18695 ENOG4107RZZ dna polymerase iii epsilon subunit GZ082_RS18705 ENOG4105D1A Methyltransferase GZ082_RS18715 ENOG4105E9H Lytic Murein transglycosylase GZ082_RS18720 ENOG4105F2W methyltransferase GZ082_RS18730 ENOG4105HEI LysR family (Transcriptional regulator GZ082_RS18735 ENOG4105CV8 reductase GZ082_RS18770 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase GZ082_RS18775 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) GZ082_RS18780 ENOG4108UMI ABC transporter, permease GZ082_RS18785 ENOG4105D01 (LipO)protein GZ082_RS18790 ENOG4108R8X outer membrane lipoprotein GZ082_RS18795 ENOG4108R96 Methyltransferase, YaeB family GZ082_RS18815 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion GZ082_RS18820 ENOG4108YZN class I peptide chain release factor GZ082_RS18825 ENOG4108VWS Yaeq family GZ082_RS18835 ENOG4105M1T rho-binding antiterminator GZ082_RS18840 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) GZ082_RS18845 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase GZ082_RS18850 ENOG4105CXN decarboxylase GZ082_RS18860 ENOG4105C0B DNA polymerase III (alpha subunit) GZ082_RS18885 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GZ082_RS18890 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) GZ082_RS18900 ENOG4105DZP Membrane-associated zinc metalloprotease GZ082_RS18905 ENOG4105KNE Phosphatidate cytidylyltransferase GZ082_RS18910 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) GZ082_RS18915 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) GZ082_RS18940 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) GZ082_RS18960 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR GZ082_RS18965 ENOG4105C0H protease GZ082_RS18980 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GZ082_RS18985 ENOG4105EN6 Membrane GZ082_RS19010 ENOG4105S6R Iron-hydroxamate transporter permease subunit GZ082_RS19015 ENOG4105J76 Periplasmic binding protein GZ082_RS19020 ENOG4105E0A ABC, transporter GZ082_RS19025 ENOG4105E0K tonB-dependent siderophore receptor GZ082_RS19030 ENOG4105BZ4 penicillin-binding protein GZ082_RS19035 ENOG4105CQ7 ATP-dependent helicase GZ082_RS19040 ENOG4107XID 2'-5' rna ligase GZ082_RS19060 ENOG4105DJ0 Poly(A) Polymerase GZ082_RS19065 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase GZ082_RS19075 ENOG4108VEV chaperone GZ082_RS19080 ENOG4105CW0 outer membrane usher protein GZ082_RS19085 ENOG4108XEY fimbrial-like adhesin protein GZ082_RS19090 ENOG4105SYG Fimbrial protein GZ082_RS19095 ENOG4105SN2 fimbrial-like adhesin protein GZ082_RS19100 ENOG4105P0Q fimbrial-like protein YadC GZ082_RS19115 ENOG4108A32 Transposase GZ082_RS19125 ENOG4107BJW polysaccharide deacetylase GZ082_RS19130 ENOG4108YTN IIa component GZ082_RS19135 ENOG4105E3A (ABC) transporter GZ082_RS19140 ENOG4105DA5 (ABC) transporter GZ082_RS19145 ENOG41077A9 carbonic anhydrase GZ082_RS19150 ENOG4108UGV hypoxanthine phosphoribosyltransferase GZ082_RS19155 ENOG4105DZG Dehydrogenase GZ082_RS19160 ENOG4105E3B Multicopper oxidase GZ082_RS19165 ENOG4108ZRK uncharacterized protein yacC GZ082_RS19185 ENOG4107QIJ Aconitate hydratase 2 GZ082_RS19190 ENOG4108NST exported protein GZ082_RS19195 ENOG4107QN2 dihydrolipoyl dehydrogenase GZ082_RS19200 ENOG4107QSN dihydrolipoamide acetyltransferase GZ082_RS19205 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) GZ082_RS19210 ENOG41073TP transcriptional regulator GZ082_RS19215 ENOG4105C85 amino acid GZ082_RS19220 ENOG4106A72 regulatory protein AmpE GZ082_RS19225 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase GZ082_RS19230 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase GZ082_RS19235 ENOG4108ZUW Major pilin subunit GZ082_RS19240 ENOG4107QHF type ii secretion system protein e GZ082_RS19245 ENOG4105D7Q type ii secretion system GZ082_RS19255 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) GZ082_RS19270 ENOG4105M6F mutator MutT protein GZ082_RS19280 ENOG4108SR7 Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) GZ082_RS19290 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) GZ082_RS19295 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) GZ082_RS19300 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) GZ082_RS19305 ENOG4105CPF Cell wall formation (By similarity) GZ082_RS19310 ENOG4105DFU Cell wall formation (By similarity) GZ082_RS19320 ENOG4105CNI cell division protein FtsW GZ082_RS19335 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) GZ082_RS19340 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) GZ082_RS19345 ENOG4105CJN penicillin-binding protein GZ082_RS19350 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) GZ082_RS19365 ENOG4107B7Y DNA-binding transcriptional regulator FruR GZ082_RS19375 ENOG4108ZP8 Acetolactate synthase small subunit GZ082_RS19380 ENOG4105C7K acetolactate synthase GZ082_RS19385 ENOG41064T2 transcriptional regulator, lysR family GZ082_RS19400 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) GZ082_RS19415 ENOG4105S8Q sugar efflux transporter GZ082_RS19425 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) GZ082_RS19430 ENOG4105DP9 ABC transporter GZ082_RS19435 ENOG4106SMU thiamine transporter membrane protein GZ082_RS19445 ENOG4108KF1 Membrane GZ082_RS19450 ENOG41063TF transcriptional regulator (AraC GZ082_RS19465 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase GZ082_RS19470 ENOG4105CQ2 DNA polymerase GZ082_RS19475 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) GZ082_RS19480 ENOG4105D3G Pseudouridine synthase GZ082_RS19485 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) GZ082_RS19490 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) GZ082_RS19495 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) GZ082_RS19515 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) GZ082_RS19520 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) GZ082_RS19535 ENOG4105C54 Major Facilitator superfamily GZ082_RS19540 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein GZ082_RS19545 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase GZ082_RS19550 ENOG4105C10 Electron transfer flavoprotein GZ082_RS19580 ENOG4106YT9 Enoyl-CoA hydratase GZ082_RS19590 ENOG4108XNW Transcriptional activatory protein CaiF GZ082_RS19595 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain GZ082_RS19600 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain GZ082_RS19620 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase GZ082_RS19625 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) GZ082_RS19630 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) GZ082_RS19635 ENOG4105DTN riboflavin biosynthesis protein ribF GZ082_RS19640 ENOG410647N response to DNA damage stimulus GZ082_RS19655 ENOG4105CW0 outer membrane usher protein GZ082_RS19660 ENOG4105CW0 outer membrane usher protein GZ082_RS19670 ENOG41063Z6 transcriptional regulator, lysR family GZ082_RS19680 ENOG4105WI6 cell killing protein encoded within cryptic prophage GZ082_RS19700 ENOG4108QUJ UPF0174 protein YaaW GZ082_RS19705 ENOG4106HK8 GPR1 FUN34 yaaH family protein GZ082_RS19710 ENOG4108RIR Molybdenum cofactor biosynthesis protein GZ082_RS19715 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GZ082_RS19720 ENOG4105BZG amino acid carrier protein GZ082_RS19735 ENOG41062C6 Protein of unknown function (DUF2502) GZ082_RS19740 ENOG4105D98 threonine synthase GZ082_RS19750 ENOG4105CFH Aspartokinase GZ082_RS19760 ENOG4106FVC RNA methyltransferase GZ082_RS19765 ENOG410759A GZ082_RS19770 ENOG41065U4 response regulator GZ082_RS19775 ENOG4105CT7 inner membrane cred family protein GZ082_RS19780 ENOG4105EB3 Histidine kinase GZ082_RS19785 ENOG4105E3W Two component transcriptional regulator (Winged helix family GZ082_RS19790 ENOG4108RH0 Crea protein GZ082_RS19795 ENOG4105UEI Transcriptional Regulator AraC Family GZ082_RS19805 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) GZ082_RS19820 ENOG4107SC1 transglycosylase GZ082_RS19825 ENOG4105C5H ABC transporter GZ082_RS19830 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase GZ082_RS19835 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) GZ082_RS19840 ENOG4105EAC phosphoserine phosphatase GZ082_RS19845 ENOG41062Z9 Membrane GZ082_RS19880 ENOG4105G0K glycine radical enzyme YjjI family GZ082_RS19885 ENOG41076CZ activating enzyme GZ082_RS19890 ENOG4105EYA deoxyribonuclease GZ082_RS19895 ENOG4108NRW Phospholipase, patatin family GZ082_RS19905 ENOG4105K3G Periplasmic Protein GZ082_RS19915 ENOG4106FE3 DNA repair GZ082_RS19925 ENOG4105W3V DNA-binding, transcriptional regulator GZ082_RS19930 ENOG4105MN3 Resolvase GZ082_RS19975 ENOG4106CZA Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC (By similarity) GZ082_RS19995 ENOG4108S1U GZ082_RS20010 ENOG4105H40 GZ082_RS20015 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) GZ082_RS20020 ENOG4108R7K Metal Dependent Phosphohydrolase GZ082_RS20025 ENOG41077V0 CPS-53 (KpLE1) prophage GZ082_RS20050 ENOG4105PAD Hydrolase GZ082_RS20055 ENOG4105KEG ribosomal-protein-alanine acetyltransferase GZ082_RS20060 ENOG4108WPU DNA polymerase III subunit psi GZ082_RS20085 ENOG4105YBH Protein of unknown function (DUF1435) GZ082_RS20090 ENOG4108819 ferric iron reductase GZ082_RS20095 ENOG4108T94 DNA-binding transcriptional activator BglJ GZ082_RS20100 ENOG4108N8T regulatoR GZ082_RS20105 ENOG4105DWK Membrane GZ082_RS20120 ENOG4106CVF DNA replication protein GZ082_RS20125 ENOG4105RI1 glycoprotein receptor GZ082_RS20135 ENOG4105CPQ Dehydrogenase GZ082_RS20140 ENOG410617M Transcriptional regulator GZ082_RS20145 ENOG4108I5G Major Facilitator superfamily GZ082_RS20150 ENOG4105C8Q Methyl-accepting chemotaxis GZ082_RS20155 ENOG4108V8F Transcriptional regulator, MarR family GZ082_RS20160 ENOG4105ERH Fumarylacetoacetate hydrolase GZ082_RS20165 ENOG4105C26 Dehydrogenase GZ082_RS20170 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase GZ082_RS20185 ENOG4105CNV Aldolase GZ082_RS20200 ENOG4105EFA 4-hydroxyphenylacetate GZ082_RS20205 ENOG4107UWN reductase GZ082_RS20210 ENOG4105D22 carbon starvation protein GZ082_RS20215 ENOG4105VCD cytoplasmic protein GZ082_RS20220 ENOG4105CKI cobalamin synthesis protein GZ082_RS20230 ENOG4106DIZ Domain of unknown function (DUF1127) GZ082_RS20235 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family GZ082_RS20250 ENOG41083G8 Multidrug resistance protein MdtM GZ082_RS20255 ENOG4106BRA Membrane GZ082_RS20260 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase GZ082_RS20265 ENOG4105CIZ coA-substrate-specific enzyme activase GZ082_RS20280 ENOG4105CBP Major Facilitator GZ082_RS20290 ENOG41074DU domain protein GZ082_RS20295 ENOG4108P2H Inner membrane protein YjiG GZ082_RS20300 ENOG4105DYB Isoaspartyl dipeptidase GZ082_RS20305 ENOG4107YNJ LysR family Transcriptional regulator GZ082_RS20325 ENOG4105C6F GntR Family Transcriptional Regulator GZ082_RS20330 ENOG4105DEI Mannitol dehydrogenase GZ082_RS20340 ENOG4107EFN gluconate transport system permease 3 GZ082_RS20345 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin GZ082_RS20350 ENOG4108T65 Fimbrial GZ082_RS20355 ENOG4108SQA Fimbrial GZ082_RS20360 ENOG4105CW0 outer membrane usher protein GZ082_RS20365 ENOG4108NAE Fimbrial chaperone protein GZ082_RS20370 ENOG4108S54 Fimbrial protein GZ082_RS20380 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off GZ082_RS20385 ENOG4108W9T type 1 fimbriae regulatory protein GZ082_RS20390 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria GZ082_RS20430 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles GZ082_RS20440 ENOG4108YGG dna repair protein GZ082_RS20445 ENOG4106549 Antirestriction protein GZ082_RS20450 ENOG4106H6R UPF0380 protein GZ082_RS20455 ENOG4105F4K antigen 43 GZ082_RS20505 ENOG4107FB0 transcriptional regulator DeoR family GZ082_RS20515 ENOG4105EDR glucose galactose transporter GZ082_RS20530 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC GZ082_RS20540 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia GZ082_RS20575 ENOG4105C9S Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity) GZ082_RS20585 ENOG4105QEK Transcriptional regulator GZ082_RS20630 ENOG4105C9U ATP-dependent DNA helicase RecQ GZ082_RS20650 ENOG4105C9U ATP-dependent DNA helicase RecQ GZ082_RS20655 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) GZ082_RS20660 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase GZ082_RS20695 ENOG4107RJ5 oxidoreductase GZ082_RS20700 ENOG4105JHE Major Facilitator Superfamily GZ082_RS20715 ENOG4108I6E Sulfatase GZ082_RS20730 ENOG4105DQ4 alcohol dehydrogenase GZ082_RS20735 ENOG4105D7A ATP-binding protein GZ082_RS20740 ENOG4108K5H permease YjgP YjgQ family protein GZ082_RS20745 ENOG4108M8S permease YjgP YjgQ family protein GZ082_RS20755 ENOG4105MYG DNA polymerase iii, chi subunit GZ082_RS20765 ENOG4108M3P Membrane GZ082_RS20770 ENOG4108MJ3 acetyltransferase GZ082_RS20775 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) GZ082_RS20795 ENOG4105XEP YhcH YjgK YiaL family protein GZ082_RS20800 ENOG4108XFH Transcriptional regulator GZ082_RS20805 ENOG4105F6U Short-chain dehydrogenase reductase Sdr GZ082_RS20810 ENOG4108UQ8 endoribonuclease L-psp GZ082_RS20815 ENOG4107C93 pyrBI operon leader peptide GZ082_RS20830 ENOG4105KME endoribonuclease L-psp GZ082_RS20840 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GZ082_RS20850 ENOG4105D4X repressor GZ082_RS20855 ENOG4105C5Y PTS System GZ082_RS20860 ENOG4105CG3 alpha amylase, catalytic region GZ082_RS20865 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase GZ082_RS20870 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) GZ082_RS20880 ENOG4105CMS peptidase U62, modulator of DNA gyrase GZ082_RS20890 ENOG4105DFU Cell wall formation (By similarity) GZ082_RS20900 ENOG41062B0 ABC transporter, permease GZ082_RS20905 ENOG4107R9N ABC transporter GZ082_RS20910 ENOG4105C2J ABC transporter GZ082_RS20915 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator GZ082_RS20920 ENOG4105F0N pyrophosphate phospho-hydrolase GZ082_RS20925 ENOG4108ZHD aig2 family GZ082_RS20930 ENOG4105MA0 exported protein GZ082_RS20935 ENOG4105CFU surface antigen GZ082_RS20945 ENOG4105C37 (CBS) domain GZ082_RS20950 ENOG41061GZ Protein of unknown function (DUF1107) GZ082_RS20955 ENOG4108UUE Transcriptional regulator GZ082_RS20960 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase GZ082_RS20965 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic GZ082_RS20970 ENOG4105KVH Transcriptional regulator GZ082_RS20975 ENOG4105ECR NmrA family GZ082_RS20980 ENOG4105DXC membrane GZ082_RS20990 ENOG4105C85 amino acid GZ082_RS20995 ENOG4108V1T peptidylprolyl cis-trans isomerase GZ082_RS21000 ENOG4105FHY Opacity-associated protein A GZ082_RS21010 ENOG4105CHR reductase GZ082_RS21020 ENOG4105E39 Enoyl-CoA hydratase GZ082_RS21025 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) GZ082_RS21035 ENOG4105DPW Major facilitator superfamily MFS_1 GZ082_RS21045 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) GZ082_RS21060 ENOG4105KIT UPF0379 protein yjfY GZ082_RS21085 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport GZ082_RS21090 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC GZ082_RS21105 ENOG4108MXZ Esterase GZ082_RS21110 ENOG4105WSB biofilm stress and motility protein A GZ082_RS21115 ENOG4105S17 UPF0379 protein yjfN GZ082_RS21120 ENOG4105CSU acyl-Coa dehydrogenase GZ082_RS21125 ENOG4106032 Glutathionylspermidine synthase GZ082_RS21130 ENOG4108KXT Conserved Protein GZ082_RS21135 ENOG4105Z6B inner membrane protein yjfl GZ082_RS21140 ENOG4107VNS Protein of unknown function (DUF2491) GZ082_RS21145 ENOG4108P9J Phage shock protein A GZ082_RS21150 ENOG4105FUX Conserved Protein GZ082_RS21155 ENOG4105C2N RNA methyltransferase TrmH family group 3 GZ082_RS21160 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) GZ082_RS21180 ENOG4105EPW hflc protein GZ082_RS21185 ENOG4107QJR hflk protein GZ082_RS21190 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) GZ082_RS21210 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GZ082_RS21215 ENOG4105K8N protein family UPF0079, ATPase GZ082_RS21220 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) GZ082_RS21225 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) GZ082_RS21265 ENOG4105EGS Mechanosensitive ion channel GZ082_RS21270 ENOG4107SC7 Inner membrane transporter yjeM GZ082_RS21280 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) GZ082_RS21285 ENOG4105E33 succinate dehydrogenase GZ082_RS21300 ENOG41066YJ Beta-lactamase GZ082_RS21305 ENOG4105QNF Outer membrane lipoprotein GZ082_RS21310 ENOG4105KPY Small multidrug resistance protein GZ082_RS21315 ENOG4106BSU Entericidin B GZ082_RS21320 ENOG4107PEH Entericidin EcnA/B family GZ082_RS21330 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein GZ082_RS21335 ENOG4105MTB Uncharacterized protein YjeJ GZ082_RS21345 ENOG4108ZVF (LipO)protein GZ082_RS21360 ENOG4105DVH amino acid GZ082_RS21365 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 GZ082_RS21370 ENOG4108IJ0 Aspartate ammonia-lyase GZ082_RS21375 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GZ082_RS21385 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) GZ082_RS21390 ENOG4108SIC Transcriptional regulator GZ082_RS21400 ENOG4108M3R transcriptional activator CadC GZ082_RS21405 ENOG4105D5Q Arginine ornithine antiporter GZ082_RS21410 ENOG4105CXN decarboxylase GZ082_RS21415 ENOG4105DUX Transporter GZ082_RS21420 ENOG4105CRK lysyL-tRNA synthetase GZ082_RS21435 ENOG410830R acetyltransferase GZ082_RS21440 ENOG4105VR1 Pfam:DUF1271 GZ082_RS21450 ENOG4108MRH transcriptional regulatory protein GZ082_RS21455 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter GZ082_RS21460 ENOG4107GFK fumarate GZ082_RS21465 ENOG4108R5S membrane GZ082_RS21470 ENOG4105CT4 transporter GZ082_RS21475 ENOG4105F8D glycoside hydrolase family 4 GZ082_RS21480 ENOG4108K2B transcriptional regulator GZ082_RS21485 ENOG4105CXN decarboxylase GZ082_RS21490 ENOG4106ZGR Transcriptional regulator GZ082_RS21495 ENOG4105D5Q Arginine ornithine antiporter GZ082_RS21500 ENOG4105DIJ Phosphoethanolamine transferase GZ082_RS21505 ENOG4105XJC Two component transcriptional regulator (Winged helix family GZ082_RS21510 ENOG4105ECM Sensor protein basS pmrB GZ082_RS21520 ENOG4105CSH Transporter GZ082_RS21525 ENOG4108YIV GZ082_RS21530 ENOG4108F5E vimentin GZ082_RS21535 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA GZ082_RS21540 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase GZ082_RS21545 ENOG4105D5T phosphonate abc transporter GZ082_RS21550 ENOG4105EHI Phosphonate ABC transporter, periplasmic GZ082_RS21560 ENOG4107RJJ Transcriptional regulator GZ082_RS21565 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG GZ082_RS21570 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH GZ082_RS21575 ENOG4105EKV Phosphonate metabolism protein GZ082_RS21580 ENOG4105FT8 Phosphonate metabolism GZ082_RS21585 ENOG4105ENV phosphonate C-P lyase system protein PhnK GZ082_RS21590 ENOG4105HRV phosphonate c-p lyase system protein phnl GZ082_RS21595 ENOG4105FD8 phosphonate metabolism protein PhnM GZ082_RS21600 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) GZ082_RS21605 ENOG410849A acetyltransferase, (GNAT) family GZ082_RS21610 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein GZ082_RS21620 ENOG4108YZG isomerase GZ082_RS21625 ENOG4105EUZ Beta-lactamase domain protein GZ082_RS21630 ENOG4106833 GZ082_RS21635 ENOG4105J12 Multidrug resistance protein mdtN GZ082_RS21640 ENOG4108MI0 Resistance protein GZ082_RS21645 ENOG4105ETP RND efflux system, outer membrane lipoprotein GZ082_RS21655 ENOG41082ND Uncharacterized protein yjcO GZ082_RS21665 ENOG4105CK2 sodium dicarboxylate symporter GZ082_RS21670 ENOG4108W0S formate-dependent nitrite reductase complex GZ082_RS21680 ENOG4108QKW cytochrome c-type biogenesis protein GZ082_RS21685 ENOG4105DVI reductase, NrfD GZ082_RS21690 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GZ082_RS21695 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit GZ082_RS21705 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GZ082_RS21710 ENOG41062QD Membrane GZ082_RS21725 ENOG4105EEQ Na H antiporter GZ082_RS21730 ENOG4105C7N Xanthine uracil vitamin C permease GZ082_RS21735 ENOG4108Z4X TRANSCRIPTIONal GZ082_RS21740 ENOG4108W3Q Transcriptional regulator GZ082_RS21745 ENOG4108M8H domain protein GZ082_RS21750 ENOG4105PMV Membrane GZ082_RS21755 ENOG4108UUM single-stranded DNA-binding protein GZ082_RS21760 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) GZ082_RS21765 ENOG4105MSB protein, conserved in bacteria GZ082_RS21770 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme GZ082_RS21775 ENOG4105F0S class B acid phosphatase GZ082_RS21785 ENOG4105CGF Aromatic amino acid aminotransferase GZ082_RS21790 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GZ082_RS21795 ENOG4105CDU Replicative dna helicase GZ082_RS21800 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein GZ082_RS21805 ENOG4105P4Z Phage shock protein G GZ082_RS21810 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GZ082_RS21820 ENOG4105MYN Zinc uptake regulation protein GZ082_RS21825 ENOG4105VDW Csbd family GZ082_RS21830 ENOG4107R73 Mate efflux family protein GZ082_RS21840 ENOG41080IJ Diacylglycerol kinase GZ082_RS21865 ENOG4107W52 maltose operon periplasmic protein GZ082_RS21875 ENOG4108IJ9 (ABC) transporter GZ082_RS21880 ENOG4107FKK extracellular solute-binding protein family 1 GZ082_RS21885 ENOG4105D56 permease protein GZ082_RS21890 ENOG4105EG2 ABC transporter, permease GZ082_RS21895 ENOG4107QNK )-transporter GZ082_RS21910 ENOG4105E3R (LipO)protein GZ082_RS21915 ENOG4108Q9C Periplasmic Protein GZ082_RS21920 ENOG4108MDC (LipO)protein GZ082_RS21935 ENOG4105CFH Aspartokinase GZ082_RS21940 ENOG4108WZA zeta toxin GZ082_RS21945 ENOG410756H nucleotidyltransferase GZ082_RS21955 ENOG4108ZR5 Conserved Protein GZ082_RS21960 ENOG4105FE9 pseudouridine synthase GZ082_RS21970 ENOG4105EAM Na Pi-cotransporter GZ082_RS21975 ENOG4105C3R Methionine synthase GZ082_RS21980 ENOG41069M3 Transcriptional regulator GZ082_RS21995 ENOG4108I9X Isocitrate lyase GZ082_RS22000 ENOG4107QP3 malate synthase g GZ082_RS22010 ENOG4105K5X acetyltransferase GZ082_RS22040 ENOG4105C12 Phosphoribosylglycinamide synthetase GZ082_RS22045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GZ082_RS22050 ENOG4105BZU Histidine kinase GZ082_RS22055 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism GZ082_RS22060 ENOG4108T8B Protein of unknown function (DUF1481) GZ082_RS22070 ENOG4105R2J Conserved Protein GZ082_RS22105 ENOG4105D06 uba thif-type nad fad binding protein GZ082_RS22110 ENOG4105WHD thiamine biosynthesis protein ThiS GZ082_RS22120 ENOG4105D41 biosynthesis protein thiH GZ082_RS22125 ENOG410645W Thiamin biosynthesis protein ThiH GZ082_RS22160 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) GZ082_RS22165 ENOG4105PM1 preprotein translocase subunit SecE GZ082_RS22200 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase GZ082_RS22245 ENOG4108Y73 Membrane GZ082_RS22250 ENOG4105EJ2 Transcriptional regulator GZ082_RS22260 ENOG4105C5Q Transcriptional regulator GZ082_RS22265 ENOG4108I5G Major Facilitator superfamily GZ082_RS22270 ENOG4105CXK mandelate racemase muconate lactonizing GZ082_RS22285 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase GZ082_RS22300 ENOG4105DIJ Phosphoethanolamine transferase GZ082_RS22305 ENOG4106R3P AraC family transcriptional regulator GZ082_RS22310 ENOG4108XCZ PTS System GZ082_RS22315 ENOG4108AHH pyruvate formate lyase II activase GZ082_RS22325 ENOG4108YRF PTS System GZ082_RS22330 ENOG4105DM4 PTS System GZ082_RS22335 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) GZ082_RS22340 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GZ082_RS22345 ENOG4105DCT glycerol dehydrogenase GZ082_RS22350 ENOG4108XC3 NADH ubiquinone oxidoreductase GZ082_RS22355 ENOG4108Q5Y Membrane GZ082_RS22365 ENOG4105SYT Methylenetetrahydrofolate reductase GZ082_RS22370 ENOG4105CFH Aspartokinase GZ082_RS22375 ENOG4105C28 cystathionine GZ082_RS22385 ENOG4107S01 Repressor protein MetJ GZ082_RS22400 ENOG4105CNA YD repeat protein GZ082_RS22410 ENOG4105C25 Primosomal protein n' GZ082_RS22415 ENOG4105ETE Transcriptional regulator (LacI family GZ082_RS22420 ENOG41063M6 Cell Division Protein GZ082_RS22435 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase GZ082_RS22450 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) GZ082_RS22460 ENOG4105CBT Fructose-1,6-bisphosphatase GZ082_RS22465 ENOG4105DP0 ferredoxin-NADP reductase GZ082_RS22475 ENOG41065TG regulatoR GZ082_RS22480 ENOG4108VTS Membrane GZ082_RS22485 ENOG4105EBK exported protein GZ082_RS22500 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein GZ082_RS22515 ENOG4105FMW periplasmic GZ082_RS22520 ENOG4105E3W Two component transcriptional regulator (Winged helix family GZ082_RS22525 ENOG4105E0F Histidine kinase GZ082_RS22530 ENOG4108RPX mosc domain containing protein GZ082_RS22540 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GZ082_RS22580 ENOG41064BA PTS system, fructose-specific, IIA component GZ082_RS22585 ENOG4105DM4 PTS System GZ082_RS22590 ENOG4105CN9 Peptidase m42 family protein GZ082_RS22595 ENOG4106C3V frv operon regulatory protein GZ082_RS22600 ENOG4108V87 frv operon regulatory protein GZ082_RS22615 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein GZ082_RS22620 ENOG4108MG3 formate dehydrogenase GZ082_RS22630 ENOG41068KX affects formate dehydrogenase-N GZ082_RS22645 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system GZ082_RS22655 ENOG4105SUU thioesterase domain GZ082_RS22670 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 GZ082_RS22675 ENOG4105E98 transcriptional regulator DeoR family GZ082_RS22680 ENOG4108MGF sugar kinase GZ082_RS22685 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase GZ082_RS22690 ENOG4105D2M Aldolase GZ082_RS22695 ENOG4107QKS N-acylglucosamine 2-epimerase GZ082_RS22700 ENOG4107WI4 Aldose-1-epimerase GZ082_RS22705 ENOG4105CJQ hydrolase, family 31 GZ082_RS22710 ENOG4105CT4 transporter GZ082_RS22715 ENOG4105CT4 transporter GZ082_RS22720 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is GZ082_RS22725 ENOG4105R9B Major Facilitator GZ082_RS22730 ENOG4108KHF Resistance protein GZ082_RS22735 ENOG4108K85 Transcriptional regulator GZ082_RS22740 ENOG4105CI3 gtp-binding protein typa GZ082_RS22745 ENOG4105C5F glutamine synthetase GZ082_RS22750 ENOG4105CUX Signal transduction histidine kinase GZ082_RS22755 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GZ082_RS22760 ENOG4106FIY GZ082_RS22765 ENOG4105D4P Coproporphyrinogen iii oxidase GZ082_RS22780 ENOG4105C2M dna polymerase I GZ082_RS22785 ENOG4106HNH Acyl-transferase GZ082_RS22795 ENOG4108Z33 Thiol disulfide Interchange Protein GZ082_RS22800 ENOG4105E27 serine threonine protein kinase GZ082_RS22805 ENOG4105PC1 Conserved Protein GZ082_RS22810 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) GZ082_RS22815 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b GZ082_RS22845 ENOG4108RR8 protoporphyrinogen oxidase GZ082_RS22850 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) GZ082_RS22855 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein GZ082_RS22875 ENOG4108EX3 reductase GZ082_RS22880 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) GZ082_RS22885 ENOG4105MDZ Transcriptional activator rfaH GZ082_RS22895 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) GZ082_RS22900 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) GZ082_RS22905 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) GZ082_RS22915 ENOG4105JC1 sterol-binding domain protein GZ082_RS22925 ENOG4105CGY Dna recombination protein GZ082_RS22930 ENOG4108I5U Uridine phosphorylase GZ082_RS22935 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) GZ082_RS22945 ENOG4105DZ2 Transcriptional regulator GZ082_RS22950 ENOG4105EMK carboxylate amino acid amine transporter GZ082_RS22955 ENOG4105DQF Hydrolase GZ082_RS22960 ENOG4108EUD Lysophospholipase GZ082_RS22965 ENOG410829K Lysine exporter protein (Lyse ygga) GZ082_RS22970 ENOG4105CCF Lysine exporter protein (Lyse ygga) GZ082_RS22975 ENOG4105C9U ATP-dependent DNA helicase RecQ GZ082_RS22980 ENOG4105HDD phospholipase GZ082_RS22985 ENOG4108VUY thioesterase Superfamily protein GZ082_RS22990 ENOG4105FR1 rard protein GZ082_RS23000 ENOG4107QUT magnesium and cobalt transport protein CorA GZ082_RS23015 ENOG4107QUT magnesium and cobalt transport protein CorA GZ082_RS23020 ENOG4108T58 Mg2 transport protein CorA GZ082_RS23025 ENOG4105C4R Atp-dependent dna helicase GZ082_RS23030 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant GZ082_RS23040 ENOG4105CT0 Protein of unknown function, DUF484 GZ082_RS23050 ENOG4105S7Z (LipO)protein GZ082_RS23075 ENOG4107T0K Adenylate cyclase GZ082_RS23085 ENOG41076E6 Uroporphyrinogen-III Synthase GZ082_RS23090 ENOG4105ECF c-methyltransferase GZ082_RS23095 ENOG410601J HemY protein GZ082_RS23100 ENOG4105ENH Sulfatase GZ082_RS23105 ENOG4105C4X radical SAM domain protein GZ082_RS23130 ENOG4105C85 amino acid GZ082_RS23145 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) GZ082_RS23150 ENOG4105EGZ biosynthesis protein GZ082_RS23155 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase GZ082_RS23160 ENOG4108WJ1 acetyltransferase GZ082_RS23165 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) GZ082_RS23170 ENOG4105C1B dTDP-glucose 4-6-dehydratase GZ082_RS23175 ENOG4107QQG Dehydrogenase GZ082_RS23180 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase GZ082_RS23185 ENOG4105SFE lipopolysaccharide biosynthesis protein GZ082_RS23190 ENOG4105ESV Glycosyl transferase, family 4 GZ082_RS23195 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) GZ082_RS23220 ENOG4105C4R Atp-dependent dna helicase GZ082_RS23230 ENOG4105KQ5 peptidylprolyl cis-trans isomerase GZ082_RS23240 ENOG4105EMY transcriptional regulator GZ082_RS23245 ENOG4105C7B Threonine dehydratase GZ082_RS23255 ENOG4105CM2 brancheD-chain amino acid aminotransferase GZ082_RS23260 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit GZ082_RS23280 ENOG4105C0P Mg chelatase subunit ChlI GZ082_RS23285 ENOG4108WFC UPF0438 protein yifE GZ082_RS23325 ENOG4107EJG GntR family transcriptional regulator GZ082_RS23330 ENOG4105C0R drug resistance transporter emrb qaca subfamily GZ082_RS23335 ENOG4105ETE Transcriptional regulator (LacI family GZ082_RS23340 ENOG4108RVA ribokinase GZ082_RS23345 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GZ082_RS23350 ENOG4105CNN ABC, transporter GZ082_RS23355 ENOG4105C2J ABC transporter GZ082_RS23385 ENOG4108VVK transcriptional Regulator, AsnC GZ082_RS23390 ENOG4105QTB Flavodoxin GZ082_RS23405 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation GZ082_RS23455 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) GZ082_RS23460 ENOG4108RQP Major type 1 subunit fimbrin GZ082_RS23470 ENOG4105CW0 outer membrane usher protein GZ082_RS23480 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) GZ082_RS23485 ENOG4105C8U phosphate abc transporter GZ082_RS23490 ENOG4105E2Z phosphate ABC transporter (Permease GZ082_RS23495 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GZ082_RS23500 ENOG4108UTW Plays a role in the regulation of phosphate uptake GZ082_RS23505 ENOG4105CID antiterminator GZ082_RS23510 ENOG4105C5Y PTS System GZ082_RS23515 ENOG4105CS2 ec 3.2.1.21 GZ082_RS23530 ENOG4107VKM 6-phosphogluconolactonase GZ082_RS23540 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 GZ082_RS23545 ENOG4105C7N Xanthine uracil vitamin C permease GZ082_RS23550 ENOG4108YYH Nadph-dependent fmn reductase GZ082_RS23555 ENOG4105E8Q phosphopantetheinyl transferase GZ082_RS23565 ENOG4105CNH Multidrug resistance protein MdtL GZ082_RS23570 ENOG4108P6C Tryptophan transporter of low affinity GZ082_RS23605 ENOG4105VG0 50S ribosomal protein l34 GZ082_RS23645 ENOG4107QJE Chromosome Partitioning Protein GZ082_RS23680 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) GZ082_RS23700 ENOG4108Z9I -acetyltransferase GZ082_RS23730 ENOG4108X73 DNA- binding protein GZ082_RS23735 ENOG4105KF5 hemolysin expression-modulating protein GZ082_RS23740 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GZ082_RS23750 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GZ082_RS23755 ENOG4105KK6 nuclease GZ082_RS23840 ENOG4105MDZ Transcriptional activator rfaH GZ082_RS23890 ENOG4105K4U addiction module toxin, RelE StbE family GZ082_RS23910 ENOG4107TV1 YD repeat protein GZ082_RS23935 ENOG4106JVB Replication Protein GZ082_RS23960 ENOG4105DFE Dna adenine methylase GZ082_RS24000 ENOG4106JVB Replication Protein GZ082_RS24020 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) GZ082_RS24155 ENOG4108BUD transposase GZ082_RS24175 ENOG4105MVE transcriptional regulator GZ082_RS24180 ENOG4108J4B Beta-lactamase GZ082_RS24185 ENOG4108BUD transposase GZ082_RS24215 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) GZ082_RS24230 ENOG4105EQR Transposase IS116 IS110 IS902 GZ082_RS24245 ENOG4108BUD transposase GZ082_RS24310 ENOG4108BUD transposase GZ082_RS24390 ENOG41085W3 Transposase GZ082_RS24410 ENOG4105K4U addiction module toxin, RelE StbE family GZ082_RS24415 ENOG41074AV Hok/gef family GZ082_RS24570 ENOG4105GMB type VI secretion system effector, hcp1 family GZ082_RS24585 ENOG4105T95 Thiol disulfide interChange protein GZ082_RS24605 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) GZ082_RS24625 ENOG4105F2I Transposase GZ082_RS24660 ENOG4105CAU Arsenical resistance protein, ArsH GZ082_RS24665 ENOG4105KBH arsR family transcriptional regulator GZ082_RS24675 ENOG4105K89 arsenate reductase GZ082_RS24685 ENOG4105CHH sulfate transporter GZ082_RS24760 ENOG41061MD high-affinity nickel-transporter GZ082_RS24770 ENOG4105GR3 Histidine kinase GZ082_RS24780 ENOG4105DIJ Phosphoethanolamine transferase GZ082_RS24790 ENOG4108BUD transposase GZ082_RS24820 ENOG4108YX2 DNA-binding protein GZ082_RS24855 ENOG4105XIV Mercuric transport protein, periplasmic component GZ082_RS24870 ENOG4108X6F Transcriptional regulator MerD GZ082_RS24895 ENOG4105VUF Transcriptional regulator GZ082_RS24900 ENOG4105EQR Transposase IS116 IS110 IS902 GZ082_RS24920 ENOG4105CAF HipA N-terminal domain protein GZ082_RS25035 ENOG4105DAX Pfam:DUF2983 GZ082_RS25065 ENOG4108M24 von Willebrand factor, type A GZ082_RS25070 ENOG4108M24 von Willebrand factor, type A GZ082_RS25120 ENOG4108BUD transposase GZ082_RS25135 ENOG4108BUD transposase GZ082_RS25240 ENOG4105C4R Atp-dependent dna helicase GZ082_RS25665 ENOG41073YN Protein of unknown function (DUF1380) GZ082_RS25710 ENOG4105FEQ ParB domain protein nuclease GZ082_RS25925 ENOG4105CZX twitching motility protein GZ082_RS25975 ENOG4105K5T PilT protein GZ082_RS25990 ENOG4108NC2 Outer membrane protease GZ082_RS26045 ENOG4105DIK (ABC) transporter GZ082_RS26050 ENOG4105CC5 ABC transporter GZ082_RS26055 ENOG4105CC5 ABC transporter GZ082_RS26070 ENOG41082CG Protein CrcB homolog GZ082_RS26090 ENOG4105DUU IucA IucC family protein GZ082_RS26095 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) GZ082_RS26160 ENOG41074AV Hok/gef family GZ082_RS26360 ENOG4107U2T alpha beta GZ082_RS26365 ENOG4107CBI conjugal transfer fertility inhibition protein GZ082_RS26400 ENOG4106CQM replication GZ082_RS26445 ENOG4108KTG Membrane protein, drug metabolite transporter GZ082_RS26470 ENOG4108BUD transposase GZ082_RS26485 ENOG4108BUD transposase GZ082_RS26500 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) GZ082_RS26510 ENOG4108BUD transposase GZ082_RS26535 ENOG4108YXQ IS66 Orf2 family protein GZ082_RS26545 ENOG4105H3G oxidoreductase GZ082_RS26575 ENOG4108MBX Secretion Protein GZ082_RS26600 ENOG4107RNH Outer membrane receptor FepA GZ082_RS26605 ENOG4105NIV Esterase GZ082_RS26610 ENOG4105E93 esterase GZ082_RS26635 ENOG4105QYK bacteriophage lambda Bor protein homolog GZ082_RS26680 ENOG4105ENJ RND efflux system, outer membrane lipoprotein GZ082_RS26690 ENOG4105DJY efflux transporter, rnd family, mfp subunit