locus-tag	class	description
RG42_RS00005	COG1763	Mo-molybdopterin cofactor biosynthetic process
RG42_RS00010	COG0746	molybdenum cofactor guanylyltransferase activity
RG42_RS00015	COG3084	Protein conserved in bacteria
RG42_RS00020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RG42_RS00025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RG42_RS00030	COG5339	Protein conserved in bacteria
RG42_RS00035	COG0204	Acyl-transferase
RG42_RS00045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RG42_RS00045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RG42_RS00065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RG42_RS00075	COG2204	response regulator
RG42_RS00080	COG3852	Histidine kinase
RG42_RS00085	COG0174	glutamine synthetase
RG42_RS00095	COG1217	gtp-binding protein TYPA
RG42_RS00100	COG2188	Transcriptional regulator
RG42_RS00105	COG1082	Xylose isomerase domain protein TIM barrel
RG42_RS00110	COG2271	Major facilitator Superfamily
RG42_RS00115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RG42_RS00120	COG2211	Major facilitator Superfamily
RG42_RS00125	COG2211	Major facilitator Superfamily
RG42_RS00130	COG1501	Belongs to the glycosyl hydrolase 31 family
RG42_RS00135	COG2017	converts alpha-aldose to the beta-anomer
RG42_RS00140	COG2942	2-epimerase
RG42_RS00145	COG3684	Belongs to the aldolase LacD family
RG42_RS00150	COG2084	Dehydrogenase
RG42_RS00155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS00160	COG1349	DNA-binding transcription factor activity
RG42_RS00165	COG1011	Hydrolase
RG42_RS00180	COG0456	acetyltransferase
RG42_RS00185	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG42_RS00190	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG42_RS00205	COG2864	formate dehydrogenase
RG42_RS00210	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS00235	COG3711	transcriptional antiterminator
RG42_RS00235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS00240	COG1363	Peptidase, m42
RG42_RS00245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS00245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS00250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS00295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RG42_RS00315	COG2258	MOSC domain
RG42_RS00320	COG2205	protein histidine kinase activity
RG42_RS00325	COG0745	RESPONSE REGULATOR receiver
RG42_RS00330	COG3678	ATP-independent chaperone mediated protein folding
RG42_RS00345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RG42_RS00370	COG3152	Membrane
RG42_RS00375	COG3691	Protein conserved in bacteria
RG42_RS00380	COG0589	response to stress
RG42_RS00385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG42_RS00390	COG1494	fructose-1,6-bisphosphatase
RG42_RS00400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RG42_RS00415	COG1575	Belongs to the MenA family. Type 1 subfamily
RG42_RS00430	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RG42_RS00435	COG1609	Transcriptional regulator
RG42_RS00440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RG42_RS00450	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
RG42_RS00460	COG0626	cystathionine gamma-synthase activity
RG42_RS00465	COG0527	aspartate kinase activity
RG42_RS00465	COG0460	homoserine dehydrogenase
RG42_RS00475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RG42_RS00485	COG0697	spore germination
RG42_RS00490	COG3738	Protein conserved in bacteria
RG42_RS00500	COG0371	Dehydrogenase
RG42_RS00505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RG42_RS00510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS00510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG42_RS00510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS00515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS00520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS00525	COG1882	Formate acetyltransferase
RG42_RS00530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG42_RS00535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS00540	COG2207	Transcriptional regulator
RG42_RS00550	COG2194	sulfuric ester hydrolase activity
RG42_RS00570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RG42_RS00585	COG0583	DNA-binding transcription factor activity
RG42_RS00600	COG1309	transcriptional regulator
RG42_RS00615	COG4206	TonB-dependent receptor
RG42_RS00650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RG42_RS00655	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RG42_RS00655	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RG42_RS00700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RG42_RS00705	COG0250	Participates in transcription elongation, termination and antitermination
RG42_RS00750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RG42_RS00760	COG2104	thiamine diphosphate biosynthetic process
RG42_RS00765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RG42_RS00800	COG3068	Protein conserved in bacteria
RG42_RS00815	COG3678	ATP-independent chaperone mediated protein folding
RG42_RS00825	COG4191	Histidine kinase
RG42_RS00830	COG2204	response regulator
RG42_RS00835	COG0151	Belongs to the GarS family
RG42_RS00880	COG0456	acetyltransferase
RG42_RS00890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RG42_RS00895	COG2224	Isocitrate lyase
RG42_RS00915	COG1414	Transcriptional regulator
RG42_RS00920	COG0646	methionine synthase
RG42_RS00920	COG1410	methionine synthase
RG42_RS00925	COG1283	sodium-dependent phosphate transmembrane transporter activity
RG42_RS00935	COG1187	pseudouridine synthase activity
RG42_RS00945	COG0527	aspartate kinase activity
RG42_RS00975	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG42_RS00995	COG0477	Major facilitator Superfamily
RG42_RS00995	COG2814	Major facilitator Superfamily
RG42_RS01000	COG3833	ABC-type maltose transport systems, permease component
RG42_RS01005	COG1175	transmembrane transport
RG42_RS01010	COG2182	Extracellular solute-binding protein
RG42_RS01020	COG3842	ATPase activity
RG42_RS01040	COG1357	PFAM Pentapeptide repeats (8 copies)
RG42_RS01070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RG42_RS01080	COG0534	Mate efflux family protein
RG42_RS01085	COG3237	CsbD-like
RG42_RS01090	COG0735	belongs to the Fur family
RG42_RS01105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RG42_RS01115	COG0604	alcohol dehydrogenase
RG42_RS01120	COG0305	Participates in initiation and elongation during chromosome replication
RG42_RS01125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RG42_RS01130	COG1448	Aminotransferase
RG42_RS01140	COG3700	Belongs to the class B bacterial acid phosphatase family
RG42_RS01145	COG0432	Pfam Uncharacterised protein family UPF0047
RG42_RS01150	COG2315	Protein conserved in bacteria
RG42_RS01155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RG42_RS01160	COG0629	single-stranded DNA binding
RG42_RS01175	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RG42_RS01180	COG2207	Transcriptional regulator
RG42_RS01185	COG0789	Transcriptional regulator
RG42_RS01205	COG2252	PERMEase
RG42_RS01210	COG0025	NhaP-type Na H and K H
RG42_RS01215	COG1357	PFAM Pentapeptide repeats (8 copies)
RG42_RS01225	COG3162	membrane
RG42_RS01230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RG42_RS01245	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
RG42_RS01250	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS01255	COG3301	Polysulphide reductase, NrfD
RG42_RS01260	COG1138	Cytochrome C-type biogenesis protein
RG42_RS01265	COG3088	subunit of a heme lyase
RG42_RS01270	COG4235	cytochrome complex assembly
RG42_RS01280	COG1301	dicarboxylic acid transport
RG42_RS01285	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RG42_RS01295	COG1538	Outer membrane efflux protein
RG42_RS01300	COG1289	transmembrane transporter activity
RG42_RS01305	COG1566	PFAM secretion protein HlyD family protein
RG42_RS01315	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RG42_RS01320	COG1940	carbohydrate kinase activity
RG42_RS01325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RG42_RS01330	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG42_RS01335	COG1129	ABC transporter
RG42_RS01340	COG1879	ABC-type sugar transport system periplasmic component
RG42_RS01345	COG1737	Transcriptional regulator
RG42_RS01355	COG0698	ribose 5-phosphate isomerase
RG42_RS01365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RG42_RS01370	COG0456	acetyltransferase
RG42_RS01375	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RG42_RS01380	COG3454	Phosphonate metabolism
RG42_RS01385	COG4778	phosphonate C-P lyase system protein PhnL
RG42_RS01395	COG4107	phosphonate C-P lyase system protein PhnK
RG42_RS01400	COG3627	carbon phosphorus lyase activity
RG42_RS01405	COG3626	phosphonate metabolism
RG42_RS01410	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
RG42_RS01415	COG3624	Phosphonate C-P lyase system protein PhnG
RG42_RS01420	COG2188	Transcriptional regulator
RG42_RS01430	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
RG42_RS01435	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RG42_RS01440	COG2764	glyoxalase bleomycin resistance protein dioxygenase
RG42_RS01450	COG2824	Alkylphosphonate utilization operon protein PhnA
RG42_RS01460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RG42_RS01470	COG0477	Major facilitator Superfamily
RG42_RS01480	COG0642	Histidine kinase
RG42_RS01485	COG0745	RESPONSE REGULATOR receiver
RG42_RS01490	COG2194	sulfuric ester hydrolase activity
RG42_RS01495	COG0531	amino acid
RG42_RS01500	COG2207	Transcriptional regulator
RG42_RS01505	COG1982	Orn Lys Arg decarboxylase major
RG42_RS01510	COG2169	Transcriptional regulator
RG42_RS01520	COG1486	melibiose metabolic process
RG42_RS01540	COG2211	Major facilitator Superfamily
RG42_RS01545	COG3647	Membrane
RG42_RS01550	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RG42_RS01550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RG42_RS01555	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RG42_RS01565	COG4565	transcriptional regulatory protein
RG42_RS01570	COG3290	protein histidine kinase activity
RG42_RS01575	COG3592	Divergent 4Fe-4S mono-cluster
RG42_RS01580	COG2388	GCN5-related N-acetyl-transferase
RG42_RS01600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RG42_RS01605	COG3104	oligopeptide transport
RG42_RS01610	COG1982	Orn Lys Arg decarboxylase major
RG42_RS01615	COG0531	amino acid
RG42_RS01620	COG3710	Transcriptional regulator
RG42_RS01635	COG1309	transcriptional regulator
RG42_RS01640	COG4232	protein-disulfide reductase activity
RG42_RS01650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RG42_RS01655	COG1027	Aspartate ammonia-lyase
RG42_RS01665	COG3030	protein affecting phage T7 exclusion by the F plasmid
RG42_RS01670	COG0531	amino acid
RG42_RS01695	COG1509	lysine 2,3-aminomutase activity
RG42_RS01705	COG5510	response to toxic substance
RG42_RS01710	COG5510	response to toxic substance
RG42_RS01715	COG2076	Multidrug Resistance protein
RG42_RS01720	COG3040	lipid binding
RG42_RS01725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RG42_RS01740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RG42_RS01745	COG1053	succinate dehydrogenase
RG42_RS01755	COG0531	amino acid
RG42_RS01770	COG1511	domain protein
RG42_RS01770	COG3264	Mechanosensitive ion channel
RG42_RS01805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RG42_RS01810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RG42_RS01810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RG42_RS01815	COG0802	atpase or kinase
RG42_RS01820	COG0860	N-Acetylmuramoyl-L-alanine amidase
RG42_RS01840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RG42_RS01845	COG0330	HflC and HflK could
RG42_RS01850	COG0330	HflC and HflK could
RG42_RS01855	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
RG42_RS01870	COG0557	exoribonuclease II activity
RG42_RS01875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RG42_RS01880	COG3789	protein conserved in bacteria
RG42_RS01885	COG1842	Phage shock protein A
RG42_RS01895	COG3766	membrane
RG42_RS01900	COG5463	Belongs to the UPF0441 family
RG42_RS01905	COG0754	glutathionylspermidine amidase activity
RG42_RS01910	COG1960	acyl-CoA dehydrogenase activity
RG42_RS01925	COG3650	response to hydrogen peroxide
RG42_RS01930	COG1073	alpha beta
RG42_RS01945	COG3037	sugar-specific permease SgaT UlaA
RG42_RS01950	COG3414	Phosphotransferase system galactitol-specific IIB component
RG42_RS01995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RG42_RS02020	COG0675	Transposase, IS605 OrfB family
RG42_RS02025	COG1309	transcriptional regulator
RG42_RS02030	COG3061	Opacity-associated protein A
RG42_RS02040	COG0545	Peptidyl-prolyl cis-trans isomerase
RG42_RS02045	COG1113	amino acid transport
RG42_RS02055	COG0697	spore germination
RG42_RS02060	COG0702	epimerase
RG42_RS02065	COG1733	regulation of RNA biosynthetic process
RG42_RS02070	COG0737	Belongs to the 5'-nucleotidase family
RG42_RS02075	COG1218	3'(2'),5'-bisphosphate nucleotidase
RG42_RS02090	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
RG42_RS02100	COG1253	flavin adenine dinucleotide binding
RG42_RS02115	COG0729	surface antigen
RG42_RS02120	COG2911	Protein conserved in bacteria
RG42_RS02125	COG2105	PFAM AIG2 family protein
RG42_RS02130	COG2336	PFAM SpoVT AbrB
RG42_RS02135	COG2337	Toxic component of a toxin-antitoxin (TA) module
RG42_RS02140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RG42_RS02145	COG1879	ABC-type sugar transport system periplasmic component
RG42_RS02150	COG1129	ABC transporter
RG42_RS02155	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG42_RS02160	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG42_RS02170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RG42_RS02180	COG0312	modulator of DNA gyrase
RG42_RS02185	COG3783	Cytochrome b(562)
RG42_RS02190	COG0602	queuosine metabolic process
RG42_RS02200	COG1328	CTP reductase activity
RG42_RS02205	COG0366	Alpha amylase catalytic
RG42_RS02210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS02210	COG1263	PTS System
RG42_RS02215	COG1609	Transcriptional regulator
RG42_RS02220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RG42_RS02225	COG0251	oxidation-reduction process
RG42_RS02250	COG0251	oxidation-reduction process
RG42_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS02260	COG1309	transcriptional regulator
RG42_RS02265	COG2731	YhcH YjgK YiaL family protein
RG42_RS02280	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
RG42_RS02285	COG0456	acetyltransferase
RG42_RS02290	COG4269	membrane
RG42_RS02295	COG0525	valine-tRNA ligase activity
RG42_RS02300	COG2927	DNA polymerase III (CHI subunit)
RG42_RS02315	COG0795	lipopolysaccharide-transporting ATPase activity
RG42_RS02320	COG0795	lipopolysaccharide-transporting ATPase activity
RG42_RS02325	COG0433	COG0433 Predicted ATPase
RG42_RS02330	COG1064	alcohol dehydrogenase
RG42_RS02340	COG0582	viral genome integration into host DNA
RG42_RS02345	COG0582	viral genome integration into host DNA
RG42_RS02365	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
RG42_RS02365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RG42_RS02380	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
RG42_RS02385	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RG42_RS02395	COG0582	viral genome integration into host DNA
RG42_RS02400	COG4974	Belongs to the 'phage' integrase family
RG42_RS02415	COG3539	Fimbrial protein
RG42_RS02420	COG3121	Chaperone
RG42_RS02425	COG3188	usher protein
RG42_RS02430	COG3539	Fimbrial protein
RG42_RS02435	COG3539	Fimbrial protein
RG42_RS02440	COG3539	Fimbrial protein
RG42_RS02450	COG2610	gluconate transmembrane transporter activity
RG42_RS02465	COG0246	Mannitol dehydrogenase
RG42_RS02475	COG2186	Transcriptional regulator
RG42_RS02515	COG0583	DNA-binding transcription factor activity
RG42_RS02520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RG42_RS02525	COG0700	Nucleoside recognition
RG42_RS02530	COG3366	ferrous iron transmembrane transporter activity
RG42_RS02540	COG0477	Major facilitator Superfamily
RG42_RS02555	COG1924	4 iron, 4 sulfur cluster binding
RG42_RS02560	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
RG42_RS02565	COG2733	membrane
RG42_RS02570	COG2814	Major facilitator Superfamily
RG42_RS02600	COG0523	cobalamin synthesis protein
RG42_RS02605	COG2879	small protein
RG42_RS02610	COG1966	Carbon starvation protein
RG42_RS02615	COG0840	transmembrane signaling receptor activity
RG42_RS02620	COG2271	Major facilitator Superfamily
RG42_RS02625	COG1802	Transcriptional regulator
RG42_RS02630	COG1063	alcohol dehydrogenase
RG42_RS02645	COG1484	DNA-dependent DNA replication
RG42_RS02660	COG2966	Psort location CytoplasmicMembrane, score
RG42_RS02665	COG2197	response regulator
RG42_RS02670	COG2197	response regulator
RG42_RS02675	COG4114	ferric iron reductase
RG42_RS02710	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
RG42_RS02715	COG0456	acetyltransferase
RG42_RS02720	COG1011	Hydrolase
RG42_RS02730	COG2823	Periplasmic or secreted lipoprotein
RG42_RS02740	COG4667	esterase of the alpha-beta hydrolase superfamily
RG42_RS02745	COG0084	hydrolase, TatD family'
RG42_RS02755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG42_RS02760	COG1328	CTP reductase activity
RG42_RS02800	COG0560	Phosphoserine phosphatase
RG42_RS02805	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RG42_RS02810	COG1056	cytidyltransferase-related domain
RG42_RS02810	COG3172	ATPase kinase involved in NAD metabolism
RG42_RS02820	COG0488	(ABC) transporter
RG42_RS02830	COG0741	lytic transglycosylase activity
RG42_RS02850	COG3708	Transcriptional regulator
RG42_RS02850	COG2207	Transcriptional regulator
RG42_RS02855	COG3045	CreA protein
RG42_RS02860	COG0745	RESPONSE REGULATOR receiver
RG42_RS02865	COG2205	protein histidine kinase activity
RG42_RS02870	COG4452	Inner membrane protein CreD
RG42_RS02875	COG0745	RESPONSE REGULATOR receiver
RG42_RS02885	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
RG42_RS02895	COG0527	aspartate kinase activity
RG42_RS02895	COG0460	homoserine dehydrogenase
RG42_RS02905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RG42_RS02925	COG1115	amino acid carrier protein
RG42_RS02930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RG42_RS02935	COG0521	Mo-molybdopterin cofactor biosynthetic process
RG42_RS02940	COG1584	GPR1 FUN34 yaaH family protein
RG42_RS02945	COG4735	regulation of single-species biofilm formation
RG42_RS02980	COG0583	DNA-binding transcription factor activity
RG42_RS02990	COG3188	usher protein
RG42_RS02995	COG3121	Chaperone
RG42_RS03020	COG0196	riboflavin kinase activity
RG42_RS03035	COG1047	Peptidyl-prolyl cis-trans
RG42_RS03055	COG0505	Belongs to the CarA family
RG42_RS03060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RG42_RS03115	COG0644	oxidoreductase
RG42_RS03120	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RG42_RS03125	COG2271	Major facilitator Superfamily
RG42_RS03140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RG42_RS03165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RG42_RS03170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RG42_RS03175	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RG42_RS03180	COG1357	PFAM Pentapeptide repeats (8 copies)
RG42_RS03195	COG0564	pseudouridine synthase activity
RG42_RS03205	COG0417	DNA replication proofreading
RG42_RS03210	COG0235	Class ii aldolase
RG42_RS03220	COG2160	L-arabinose isomerase activity
RG42_RS03225	COG1069	ribulokinase activity
RG42_RS03235	COG4977	sequence-specific DNA binding
RG42_RS03240	COG0586	Pfam SNARE associated Golgi protein
RG42_RS03245	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
RG42_RS03250	COG1178	ABC-type Fe3 transport system permease component
RG42_RS03255	COG4143	(ABC) transporter
RG42_RS03260	COG4533	DNA binding
RG42_RS03270	COG2814	Major facilitator Superfamily
RG42_RS03285	COG0473	3-isopropylmalate dehydrogenase activity
RG42_RS03300	COG0583	DNA-binding transcription factor activity
RG42_RS03305	COG0028	Belongs to the TPP enzyme family
RG42_RS03310	COG0440	acetolactate synthase activity
RG42_RS03320	COG1609	Transcriptional regulator
RG42_RS03330	COG2001	Belongs to the MraZ family
RG42_RS03340	COG3116	cell division
RG42_RS03345	COG0768	penicillin binding
RG42_RS03350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RG42_RS03355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RG42_RS03365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RG42_RS03370	COG0772	Belongs to the SEDS family
RG42_RS03385	COG1181	Belongs to the D-alanine--D-alanine ligase family
RG42_RS03390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RG42_RS03395	COG0849	cell division
RG42_RS03400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RG42_RS03420	COG0494	nUDIX hydrolase
RG42_RS03435	COG0237	dephospho-CoA kinase activity
RG42_RS03445	COG1459	type II secretion system
RG42_RS03450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RG42_RS03455	COG4969	Belongs to the N-Me-Phe pilin family
RG42_RS03465	COG0157	Belongs to the NadC ModD family
RG42_RS03470	COG3023	N-Acetylmuramoyl-L-alanine amidase
RG42_RS03475	COG3725	Membrane protein required for beta-lactamase induction
RG42_RS03480	COG1113	amino acid transport
RG42_RS03485	COG2186	Transcriptional regulator
RG42_RS03495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RG42_RS03500	COG0508	dehydrogenase complex catalyzes the overall conversion of
RG42_RS03505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RG42_RS03510	COG3064	Membrane
RG42_RS03520	COG1049	propionate catabolic process, 2-methylcitrate cycle
RG42_RS03545	COG2132	Multicopper oxidase
RG42_RS03550	COG4993	Dehydrogenase
RG42_RS03555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RG42_RS03560	COG0288	reversible hydration of carbon dioxide
RG42_RS03565	COG1131	(ABC) transporter
RG42_RS03570	COG0842	Transport permease protein
RG42_RS03575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS03580	COG0726	polysaccharide deacetylase
RG42_RS03600	COG5464	transposase or invertase
RG42_RS03615	COG3539	Fimbrial protein
RG42_RS03620	COG3539	Fimbrial protein
RG42_RS03625	COG3539	Fimbrial protein
RG42_RS03630	COG3539	Fimbrial protein
RG42_RS03635	COG3188	usher protein
RG42_RS03640	COG3121	Chaperone
RG42_RS03645	COG3539	Fimbrial protein
RG42_RS03650	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RG42_RS03655	COG0617	tRNA 3'-terminal CCA addition
RG42_RS03665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RG42_RS03675	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RG42_RS03680	COG1643	Atp-dependent helicase
RG42_RS03690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RG42_RS03695	COG4774	siderophore transport
RG42_RS03700	COG1120	ATPase activity
RG42_RS03705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RG42_RS03710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RG42_RS03730	COG2860	membrane
RG42_RS03735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RG42_RS03755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RG42_RS03760	COG3835	regulator
RG42_RS03770	COG1408	metallophosphoesterase
RG42_RS03785	COG0024	Methionine aminopeptidase
RG42_RS03820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RG42_RS03825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RG42_RS03830	COG0575	Belongs to the CDS family
RG42_RS03835	COG0750	zinc metalloprotease
RG42_RS03845	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
RG42_RS03850	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RG42_RS03875	COG0587	DNA-directed DNA polymerase activity
RG42_RS03885	COG1982	Orn Lys Arg decarboxylase major
RG42_RS03890	COG0346	lactoylglutathione lyase activity
RG42_RS03895	COG0037	tRNA processing
RG42_RS03900	COG4568	rho-dependent transcription termination
RG42_RS03910	COG4681	YaeQ
RG42_RS03915	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RG42_RS03920	COG3015	lipoprotein NlpE involved in copper resistance
RG42_RS03925	COG0791	NLP P60 protein
RG42_RS03935	COG1720	tRNA m6t6A37 methyltransferase activity
RG42_RS03945	COG1464	Belongs to the NlpA lipoprotein family
RG42_RS03950	COG2011	ABC-type metal ion transport system permease component
RG42_RS03955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RG42_RS03960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RG42_RS03995	COG0656	L-ascorbic acid biosynthetic process
RG42_RS04000	COG0583	DNA-binding transcription factor activity
RG42_RS04010	COG2226	methyltransferase
RG42_RS04015	COG1388	LysM domain
RG42_RS04015	COG0741	lytic transglycosylase activity
RG42_RS04025	COG2226	methyltransferase
RG42_RS04035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG42_RS04055	COG4104	PAAR repeat-containing protein
RG42_RS04060	COG3157	Type VI secretion system effector, Hcp
RG42_RS04160	COG3209	COG3209 Rhs family protein
RG42_RS04175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RG42_RS04185	COG1960	acyl-CoA dehydrogenase activity
RG42_RS04195	COG0121	glutamine amidotransferase
RG42_RS04200	COG3034	peptidoglycan biosynthetic process
RG42_RS04205	COG3041	Addiction module toxin RelE StbE family
RG42_RS04210	COG3077	Addiction module antitoxin, RelB DinJ family
RG42_RS04215	COG0791	NLP P60 protein
RG42_RS04220	COG1943	Transposase
RG42_RS04245	COG2161	toxin-antitoxin pair type II binding
RG42_RS04255	COG0454	-acetyltransferase
RG42_RS04265	COG1690	Belongs to the RtcB family
RG42_RS04270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RG42_RS04275	COG2195	Cleaves the N-terminal amino acid of tripeptides
RG42_RS04295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG42_RS04315	COG0582	viral genome integration into host DNA
RG42_RS04345	COG4228	DNA circulation
RG42_RS04355	COG4372	Transposase
RG42_RS04360	COG4372	Transposase
RG42_RS04365	COG3436	PFAM IS66 Orf2 family protein
RG42_RS04390	COG3299	homolog of phage Mu protein gp47
RG42_RS04395	COG3778	Protein conserved in bacteria
RG42_RS04415	COG2030	dehydratase
RG42_RS04435	COG0583	DNA-binding transcription factor activity
RG42_RS04440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RG42_RS04450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RG42_RS04455	COG2080	2 iron, 2 sulfur cluster binding
RG42_RS04465	COG3477	response to acidic pH
RG42_RS04475	COG0727	PFAM Uncharacterised protein family (UPF0153)
RG42_RS04480	COG3121	Chaperone
RG42_RS04490	COG3188	usher protein
RG42_RS04540	COG1388	LysM domain
RG42_RS04545	COG3708	Transcriptional regulator
RG42_RS04545	COG2207	Transcriptional regulator
RG42_RS04550	COG3059	membrane
RG42_RS04560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RG42_RS04565	COG2207	Transcriptional regulator
RG42_RS04570	COG0247	lactate metabolic process
RG42_RS04575	COG1139	Iron-sulfur cluster binding protein
RG42_RS04580	COG1556	Lactate utilization protein
RG42_RS04615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RG42_RS04630	COG2200	EAL domain
RG42_RS04630	COG2771	luxR family
RG42_RS04635	COG0583	DNA-binding transcription factor activity
RG42_RS04650	COG0666	response to abiotic stimulus
RG42_RS04660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG42_RS04665	COG1304	FMN binding
RG42_RS04675	COG0549	Belongs to the carbamate kinase family
RG42_RS04680	COG0402	S-adenosylhomocysteine deaminase activity
RG42_RS04685	COG1064	alcohol dehydrogenase
RG42_RS04700	COG1280	lysine exporter protein (LysE YggA)
RG42_RS04710	COG3829	transcription factor binding
RG42_RS04715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RG42_RS04725	COG0372	Belongs to the citrate synthase family
RG42_RS04730	COG2079	MmgE PrpD family protein
RG42_RS04735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RG42_RS04745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RG42_RS04750	COG0402	S-adenosylhomocysteine deaminase activity
RG42_RS04755	COG0583	DNA-binding transcription factor activity
RG42_RS04760	COG0288	reversible hydration of carbon dioxide
RG42_RS04770	COG2807	transmembrane transport
RG42_RS04775	COG0110	maltose O-acetyltransferase activity
RG42_RS04780	COG2223	nitrite transmembrane transporter activity
RG42_RS04785	COG3250	beta-galactosidase activity
RG42_RS04795	COG1609	Transcriptional regulator
RG42_RS04800	COG1414	Transcriptional regulator
RG42_RS04820	COG3971	2-oxopent-4-enoate hydratase activity
RG42_RS04845	COG2814	Major facilitator Superfamily
RG42_RS04850	COG3122	Protein conserved in bacteria
RG42_RS04880	COG1215	transferase activity, transferring glycosyl groups
RG42_RS04885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RG42_RS04895	COG4521	taurine ABC transporter
RG42_RS04905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RG42_RS04910	COG2175	clavaminate synthase activity
RG42_RS04915	COG0113	porphobilinogen synthase activity
RG42_RS04925	COG3468	outer membrane autotransporter barrel domain protein
RG42_RS04930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RG42_RS04935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RG42_RS04945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RG42_RS04965	COG1181	Belongs to the D-alanine--D-alanine ligase family
RG42_RS04980	COG1785	Belongs to the alkaline phosphatase family
RG42_RS04990	COG3706	GGDEF domain
RG42_RS04995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RG42_RS05020	COG4126	flavin adenine dinucleotide binding
RG42_RS05045	COG1940	carbohydrate kinase activity
RG42_RS05055	COG2814	Major facilitator Superfamily
RG42_RS05060	COG0419	ATPase involved in DNA repair
RG42_RS05065	COG0420	3'-5' exonuclease activity
RG42_RS05070	COG0745	RESPONSE REGULATOR receiver
RG42_RS05075	COG5002	protein histidine kinase activity
RG42_RS05080	COG1114	Component of the transport system for branched-chain amino acids
RG42_RS05085	COG1113	amino acid transport
RG42_RS05090	COG0366	Alpha amylase catalytic
RG42_RS05110	COG1862	Preprotein translocase
RG42_RS05115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RG42_RS05120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RG42_RS05125	COG1403	HNH endonuclease
RG42_RS05130	COG3248	Nucleoside-binding outer membrane protein
RG42_RS05135	COG4238	major outer membrane lipoprotein
RG42_RS05145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RG42_RS05145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RG42_RS05160	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RG42_RS05165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RG42_RS05170	COG0667	Aldo Keto reductase
RG42_RS05180	COG0142	geranyltranstransferase activity
RG42_RS05195	COG0693	protein deglycase activity
RG42_RS05200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RG42_RS05210	COG2814	Major facilitator Superfamily
RG42_RS05220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RG42_RS05225	COG1845	cytochrome c oxidase, subunit III
RG42_RS05230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RG42_RS05235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RG42_RS05240	COG2223	nitrite transmembrane transporter activity
RG42_RS05245	COG3056	Lipoprotein
RG42_RS05255	COG0271	Belongs to the BolA IbaG family
RG42_RS05280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RG42_RS05285	COG0776	regulation of translation
RG42_RS05290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RG42_RS05295	COG1555	photosystem II stabilization
RG42_RS05300	COG0824	Thioesterase
RG42_RS05310	COG4533	DNA binding
RG42_RS05320	COG1522	sequence-specific DNA binding
RG42_RS05325	COG1132	(ABC) transporter
RG42_RS05330	COG1132	(ABC) transporter
RG42_RS05335	COG0347	Belongs to the P(II) protein family
RG42_RS05340	COG0004	ammonium transporteR
RG42_RS05345	COG1946	Acyl-CoA thioesterase
RG42_RS05350	COG3126	Type III secretion system lipoprotein chaperone (YscW)
RG42_RS05355	COG3695	enzyme binding
RG42_RS05365	COG5507	3-demethylubiquinone-9 3-methyltransferase
RG42_RS05370	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RG42_RS05380	COG0110	maltose O-acetyltransferase activity
RG42_RS05395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG42_RS05400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG42_RS05405	COG1309	transcriptional regulator
RG42_RS05415	COG3264	Mechanosensitive ion channel
RG42_RS05415	COG1196	nuclear chromosome segregation
RG42_RS05425	COG3923	Primosomal replication protein n
RG42_RS05430	COG2832	Protein of unknown function (DUF454)
RG42_RS05445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RG42_RS05480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS05485	COG4651	solute:proton antiporter activity
RG42_RS05485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RG42_RS05490	COG2223	nitrite transmembrane transporter activity
RG42_RS05500	COG0737	Belongs to the 5'-nucleotidase family
RG42_RS05505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RG42_RS05510	COG3735	TraB family
RG42_RS05515	COG3093	addiction module antidote protein HigA
RG42_RS05525	COG2217	Heavy metal translocating P-type atpase
RG42_RS05530	COG2066	Belongs to the glutaminase family
RG42_RS05535	COG0531	amino acid
RG42_RS05545	COG0789	Transcriptional regulator
RG42_RS05550	COG1585	Membrane protein implicated in regulation of membrane protease activity
RG42_RS05555	COG0330	HflC and HflK could
RG42_RS05560	COG4619	ABC transporter
RG42_RS05565	COG0390	transport system, permease component
RG42_RS05570	COG3118	belongs to the thioredoxin family
RG42_RS05575	COG0300	oxidoreductase activity
RG42_RS05580	COG2755	lipolytic protein G-D-S-L family
RG42_RS05585	COG4181	ATPase activity
RG42_RS05590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RG42_RS05595	COG3209	COG3209 Rhs family protein
RG42_RS05605	COG3209	COG3209 Rhs family protein
RG42_RS05620	COG2801	Transposase and inactivated derivatives
RG42_RS05630	COG0583	DNA-binding transcription factor activity
RG42_RS05640	COG1414	Transcriptional regulator
RG42_RS05645	COG3960	tartronate-semialdehyde synthase activity
RG42_RS05650	COG3622	Belongs to the hyi family
RG42_RS05655	COG2084	Dehydrogenase
RG42_RS05660	COG1953	Uracil, thiamine, allantoin
RG42_RS05670	COG2233	PERMEase
RG42_RS05675	COG1929	Belongs to the glycerate kinase type-1 family
RG42_RS05680	COG3257	ureidoglycine aminohydrolase activity
RG42_RS05685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RG42_RS05690	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RG42_RS05695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG42_RS05700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG42_RS05710	COG0549	Belongs to the carbamate kinase family
RG42_RS05715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RG42_RS05720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RG42_RS05735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RG42_RS05745	COG1988	membrane-bound metal-dependent
RG42_RS05750	COG2501	S4 domain
RG42_RS05760	COG3539	Fimbrial protein
RG42_RS05765	COG3121	Chaperone
RG42_RS05770	COG3188	usher protein
RG42_RS05775	COG3539	Fimbrial protein
RG42_RS05780	COG3539	Fimbrial protein
RG42_RS05785	COG2197	response regulator
RG42_RS05795	COG2207	Transcriptional regulator
RG42_RS05820	COG5002	protein histidine kinase activity
RG42_RS05825	COG0745	RESPONSE REGULATOR receiver
RG42_RS05835	COG1538	Outer membrane efflux protein
RG42_RS05840	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG42_RS05845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG42_RS05850	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG42_RS05855	COG1113	amino acid transport
RG42_RS05860	COG0668	transmembrane transport
RG42_RS05865	COG0778	Nitroreductase
RG42_RS05870	COG2315	Protein conserved in bacteria
RG42_RS05895	COG3385	transposase activity
RG42_RS05900	COG2977	Belongs to the P-Pant transferase superfamily
RG42_RS05910	COG4771	TonB-dependent receptor
RG42_RS05915	COG2382	esterase
RG42_RS05920	COG3251	PFAM MbtH domain protein
RG42_RS05925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RG42_RS05925	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RG42_RS05930	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
RG42_RS05935	COG1120	ATPase activity
RG42_RS05940	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RG42_RS05945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RG42_RS05955	COG4592	Periplasmic binding protein
RG42_RS05965	COG1169	isochorismate synthase
RG42_RS05970	COG1021	2,3-dihydroxybenzoate-AMP ligase
RG42_RS05975	COG1535	isochorismatase
RG42_RS05975	COG3433	isochorismatase activity
RG42_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS05985	COG2050	protein possibly involved in aromatic compounds catabolism
RG42_RS05990	COG1966	Carbon starvation protein
RG42_RS05995	COG2879	small protein
RG42_RS06000	COG0371	Dehydrogenase
RG42_RS06005	COG0436	Aminotransferase
RG42_RS06010	COG1475	DNA binding
RG42_RS06015	COG3969	phosphoadenosine phosphosulfate
RG42_RS06020	COG0583	DNA-binding transcription factor activity
RG42_RS06030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RG42_RS06035	COG0450	alkyl hydroperoxide reductase
RG42_RS06040	COG3634	alkyl hydroperoxide reductase activity
RG42_RS06045	COG0589	response to stress
RG42_RS06050	COG1063	alcohol dehydrogenase
RG42_RS06060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RG42_RS06070	COG3719	Belongs to the RNase T2 family
RG42_RS06075	COG0471	metal ion transport
RG42_RS06090	COG3051	citrate lyase alpha subunit
RG42_RS06095	COG2301	Belongs to the HpcH HpaI aldolase family
RG42_RS06105	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
RG42_RS06110	COG3290	protein histidine kinase activity
RG42_RS06115	COG4565	transcriptional regulatory protein
RG42_RS06120	COG3069	C4-dicarboxylate transmembrane transporter activity
RG42_RS06145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RG42_RS06150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RG42_RS06155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RG42_RS06170	COG0583	DNA-binding transcription factor activity
RG42_RS06190	COG1686	Belongs to the peptidase S11 family
RG42_RS06195	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RG42_RS06200	COG0772	Belongs to the SEDS family
RG42_RS06205	COG0768	penicillin binding
RG42_RS06215	COG0799	negative regulation of ribosome biogenesis
RG42_RS06220	COG0406	alpha-ribazole phosphatase activity
RG42_RS06230	COG1466	dna polymerase III delta subunit
RG42_RS06245	COG2888	peptidyl-tyrosine sulfation
RG42_RS06250	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RG42_RS06280	COG2214	Heat shock protein DnaJ domain protein
RG42_RS06290	COG0443	Heat shock 70 kDa protein
RG42_RS06300	COG1126	abc transporter atp-binding protein
RG42_RS06305	COG0765	amino acid transport
RG42_RS06310	COG0765	amino acid transport
RG42_RS06315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS06320	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RG42_RS06325	COG4535	Mg2 and Co2 transporter CorC
RG42_RS06335	COG1702	phosphate starvation-inducible protein PhoH
RG42_RS06345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RG42_RS06395	COG0367	asparagine synthase
RG42_RS06400	COG0647	UMP catabolic process
RG42_RS06405	COG1846	Transcriptional regulator
RG42_RS06405	COG1940	carbohydrate kinase activity
RG42_RS06410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RG42_RS06420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS06420	COG1263	PTS System
RG42_RS06420	COG2190	(PTS) system
RG42_RS06440	COG0735	belongs to the Fur family
RG42_RS06455	COG0716	FMN binding
RG42_RS06465	COG0596	Alpha beta hydrolase
RG42_RS06470	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
RG42_RS06475	COG0033	Phosphoglucomutase
RG42_RS06495	COG0531	amino acid
RG42_RS06510	COG0745	RESPONSE REGULATOR receiver
RG42_RS06515	COG2205	protein histidine kinase activity
RG42_RS06550	COG3209	COG3209 Rhs family protein
RG42_RS06565	COG3209	COG3209 Rhs family protein
RG42_RS06585	COG5433	transposase activity
RG42_RS06595	COG5433	transposase activity
RG42_RS06600	COG3272	Protein of unknown function (DUF1722)
RG42_RS06605	COG0415	Belongs to the DNA photolyase family
RG42_RS06610	COG3104	oligopeptide transport
RG42_RS06615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RG42_RS06620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RG42_RS06625	COG1984	allophanate hydrolase subunit 2
RG42_RS06640	COG3180	Ammonia monooxygenase
RG42_RS06645	COG3539	Fimbrial protein
RG42_RS06650	COG3121	Chaperone
RG42_RS06655	COG3188	usher protein
RG42_RS06660	COG3539	Fimbrial protein
RG42_RS06665	COG0372	Belongs to the citrate synthase family
RG42_RS06685	COG2009	succinate dehydrogenase
RG42_RS06690	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RG42_RS06695	COG1053	succinate dehydrogenase
RG42_RS06700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RG42_RS06710	COG0567	Dehydrogenase, E1 component
RG42_RS06715	COG0508	dehydrogenase complex catalyzes the overall conversion of
RG42_RS06725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RG42_RS06730	COG2188	Transcriptional regulator
RG42_RS06735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS06735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS06735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS06740	COG0383	alpha-mannosidase activity
RG42_RS06750	COG1271	oxidase subunit
RG42_RS06755	COG1294	oxidase, subunit
RG42_RS06760	COG4890	Cyd operon protein YbgT
RG42_RS06765	COG3790	cyd operon protein YbgE
RG42_RS06770	COG0824	Thioesterase
RG42_RS06775	COG0811	peptide transport
RG42_RS06780	COG0848	biopolymer transport protein
RG42_RS06785	COG3064	Membrane
RG42_RS06795	COG2885	chlorophyll binding
RG42_RS06800	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
RG42_RS06850	COG3201	nicotinamide mononucleotide transporter
RG42_RS06855	COG1230	cation diffusion facilitator family transporter
RG42_RS06870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RG42_RS06880	COG2017	converts alpha-aldose to the beta-anomer
RG42_RS06890	COG1085	galactose-1-phosphate uridylyltransferase
RG42_RS06895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RG42_RS06900	COG1119	ATPase activity
RG42_RS06905	COG2005	Transcriptional regulator
RG42_RS06905	COG3585	molybdate ion transport
RG42_RS06920	COG0725	ABC transporter, periplasmic molybdate-binding protein
RG42_RS06925	COG4149	molybdate abc transporter
RG42_RS06930	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RG42_RS06935	COG0561	phosphatase activity
RG42_RS06945	COG0583	DNA-binding transcription factor activity
RG42_RS06950	COG2828	Protein conserved in bacteria
RG42_RS06955	COG0471	metal ion transport
RG42_RS06960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RG42_RS06965	COG4677	pectinesterase activity
RG42_RS07025	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
RG42_RS07055	COG3772	lysozyme
RG42_RS07070	COG3646	Phage regulatory protein
RG42_RS07075	COG5562	phage envelope protein
RG42_RS07085	COG4220	transposase activity
RG42_RS07105	COG1030	water channel activity
RG42_RS07155	COG1196	nuclear chromosome segregation
RG42_RS07190	COG5301	cellulose 1,4-beta-cellobiosidase activity
RG42_RS07195	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RG42_RS07200	COG2199	diguanylate cyclase activity
RG42_RS07210	COG1881	PFAM PEBP family protein
RG42_RS07215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RG42_RS07230	COG2226	methyltransferase
RG42_RS07235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RG42_RS07245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RG42_RS07255	COG0521	Mo-molybdopterin cofactor biosynthetic process
RG42_RS07265	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RG42_RS07270	COG0314	molybdopterin synthase activity
RG42_RS07275	COG0670	Belongs to the BI1 family
RG42_RS07280	COG0670	Belongs to the BI1 family
RG42_RS07285	COG0392	lysyltransferase activity
RG42_RS07290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RG42_RS07295	COG3568	Endonuclease Exonuclease Phosphatase
RG42_RS07305	COG0842	Transport permease protein
RG42_RS07310	COG0842	Transport permease protein
RG42_RS07315	COG1131	(ABC) transporter
RG42_RS07325	COG1309	transcriptional regulator
RG42_RS07330	COG0513	Belongs to the DEAD box helicase family
RG42_RS07335	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
RG42_RS07345	COG1199	ATP-dependent helicase activity
RG42_RS07350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RG42_RS07355	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RG42_RS07365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RG42_RS07375	COG4774	siderophore transport
RG42_RS07390	COG0668	transmembrane transport
RG42_RS07400	COG1126	abc transporter atp-binding protein
RG42_RS07405	COG0765	amino acid transport
RG42_RS07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS07435	COG5006	permease, DMT superfamily
RG42_RS07440	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RG42_RS07445	COG2194	sulfuric ester hydrolase activity
RG42_RS07455	COG1321	iron dependent repressor
RG42_RS07460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RG42_RS07465	COG1376	ErfK ybiS ycfS ynhG family protein
RG42_RS07470	COG0488	(ABC) transporter
RG42_RS07480	COG0561	phosphatase activity
RG42_RS07485	COG1882	Formate acetyltransferase
RG42_RS07490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG42_RS07495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RG42_RS07500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RG42_RS07505	COG0303	'Molybdopterin
RG42_RS07510	COG1446	asparaginase
RG42_RS07515	COG4172	Belongs to the ABC transporter superfamily
RG42_RS07520	COG0747	negative chemotaxis
RG42_RS07530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG42_RS07535	COG2200	EAL domain
RG42_RS07540	COG2199	diguanylate cyclase activity
RG42_RS07555	COG2133	pyrroloquinoline quinone binding
RG42_RS07560	COG0625	glutathione transferase activity
RG42_RS07565	COG1686	Belongs to the peptidase S11 family
RG42_RS07570	COG1349	DNA-binding transcription factor activity
RG42_RS07575	COG0671	phosphoesterase, PA-phosphatase related
RG42_RS07580	COG2814	Major facilitator Superfamily
RG42_RS07590	COG0561	phosphatase activity
RG42_RS07595	COG0738	Major facilitator superfamily
RG42_RS07600	COG3226	Transcriptional regulator
RG42_RS07605	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RG42_RS07645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RG42_RS07695	COG4695	Portal protein
RG42_RS07800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RG42_RS07855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RG42_RS07865	COG0778	Nitroreductase
RG42_RS07885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RG42_RS07890	COG3842	ATPase activity
RG42_RS07895	COG1176	ABC-type spermidine putrescine transport system, permease component I
RG42_RS07900	COG1177	transmembrane transport
RG42_RS07920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS07925	COG4160	amino acid transport
RG42_RS07930	COG4215	(ABC) transporter
RG42_RS07935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS07940	COG1126	abc transporter atp-binding protein
RG42_RS07955	COG3023	N-Acetylmuramoyl-L-alanine amidase
RG42_RS07960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RG42_RS07965	COG0702	epimerase
RG42_RS07970	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RG42_RS07975	COG0028	Belongs to the TPP enzyme family
RG42_RS07980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG42_RS07990	COG2431	L-lysine efflux transmembrane transporter activity
RG42_RS08005	COG3593	DNA synthesis involved in DNA repair
RG42_RS08010	COG2990	Protein conserved in bacteria
RG42_RS08015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG42_RS08020	COG1136	(ABC) transporter
RG42_RS08020	COG0577	efflux transmembrane transporter activity
RG42_RS08025	COG1278	Cold shock
RG42_RS08035	COG0542	response to heat
RG42_RS08065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RG42_RS08070	COG4988	ABC transporter
RG42_RS08075	COG0492	ferredoxin-NADP+ reductase activity
RG42_RS08085	COG1522	sequence-specific DNA binding
RG42_RS08090	COG1674	ftsk spoiiie
RG42_RS08090	COG1178	ABC-type Fe3 transport system permease component
RG42_RS08100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RG42_RS08110	COG0243	molybdopterin cofactor binding
RG42_RS08115	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS08120	COG3302	dmso reductase anchor subunit
RG42_RS08125	COG1335	isochorismatase
RG42_RS08135	COG0531	amino acid
RG42_RS08140	COG0583	DNA-binding transcription factor activity
RG42_RS08145	COG2249	NAD(P)H dehydrogenase (quinone) activity
RG42_RS08150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RG42_RS08160	COG1944	ATP diphosphatase activity
RG42_RS08165	COG2323	membrane
RG42_RS08180	COG0501	Belongs to the peptidase M48B family
RG42_RS08190	COG0539	negative regulation of cytoplasmic translation
RG42_RS08205	COG1132	(ABC) transporter
RG42_RS08210	COG1663	tetraacyldisaccharide 4'-kinase activity
RG42_RS08215	COG3214	Protein conserved in bacteria
RG42_RS08230	COG3173	Aminoglycoside phosphotransferase
RG42_RS08235	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RG42_RS08240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RG42_RS08250	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
RG42_RS08260	COG2989	Protein conserved in bacteria
RG42_RS08270	COG3108	Peptidase M15
RG42_RS08275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RG42_RS08280	COG1448	Aminotransferase
RG42_RS08305	COG0308	aminopeptidase N
RG42_RS08310	COG1116	anion transmembrane transporter activity
RG42_RS08315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RG42_RS08325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RG42_RS08330	COG0431	NADPH-dependent FMN reductase
RG42_RS08340	COG3539	Fimbrial protein
RG42_RS08345	COG3121	Chaperone
RG42_RS08350	COG3188	usher protein
RG42_RS08355	COG3539	Fimbrial protein
RG42_RS08360	COG3539	Fimbrial protein
RG42_RS08365	COG3539	Fimbrial protein
RG42_RS08370	COG3121	Chaperone
RG42_RS08385	COG3217	Mosc domain protein beta barrel domain protein
RG42_RS08385	COG0633	Ferredoxin
RG42_RS08395	COG0488	(ABC) transporter
RG42_RS08400	COG2995	paraquat-inducible protein a
RG42_RS08405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RG42_RS08405	COG3008	intermembrane lipid transfer
RG42_RS08410	COG3009	Protein conserved in bacteria
RG42_RS08415	COG3130	regulation of translation
RG42_RS08425	COG1067	ATP-dependent peptidase activity
RG42_RS08435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RG42_RS08435	COG2885	chlorophyll binding
RG42_RS08450	COG3070	regulator of competence-specific genes
RG42_RS08455	COG1289	transmembrane transporter activity
RG42_RS08460	COG3304	Inner membrane component domain
RG42_RS08465	COG0210	DNA helicase
RG42_RS08485	COG1832	CoA-binding protein
RG42_RS08500	COG1254	Belongs to the acylphosphatase family
RG42_RS08505	COG2920	part of a sulfur-relay system
RG42_RS08510	COG0670	Belongs to the BI1 family
RG42_RS08520	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RG42_RS08525	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RG42_RS08530	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
RG42_RS08535	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RG42_RS08540	COG1999	signal sequence binding
RG42_RS08545	COG1773	rubredoxin
RG42_RS08550	COG1271	oxidase subunit
RG42_RS08555	COG1294	oxidase, subunit
RG42_RS08575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RG42_RS08580	COG1596	polysaccharide export
RG42_RS08585	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG42_RS08605	COG1278	Cold shock
RG42_RS08610	COG1278	Cold shock
RG42_RS08630	COG0348	domain, Protein
RG42_RS08635	COG2205	protein histidine kinase activity
RG42_RS08635	COG2198	Histidine kinase
RG42_RS08635	COG0784	Response regulator, receiver
RG42_RS08640	COG1879	ABC-type sugar transport system periplasmic component
RG42_RS08645	COG0745	RESPONSE REGULATOR receiver
RG42_RS08650	COG3005	denitrification pathway
RG42_RS08655	COG0243	molybdopterin cofactor binding
RG42_RS08660	COG3381	protein complex oligomerization
RG42_RS08700	COG3729	General stress protein
RG42_RS08710	COG2233	PERMEase
RG42_RS08745	COG1309	transcriptional regulator
RG42_RS08750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG42_RS08750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RG42_RS08750	COG0506	proline dehydrogenase activity
RG42_RS08765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RG42_RS08780	COG2822	iron ion transport
RG42_RS08785	COG2837	iron assimilation
RG42_RS08795	COG1702	phosphate starvation-inducible protein PhoH
RG42_RS08800	COG3658	cytochrome
RG42_RS08805	COG1215	transferase activity, transferring glycosyl groups
RG42_RS08810	COG1649	PFAM Uncharacterised BCR, COG1649
RG42_RS08810	COG0726	polysaccharide deacetylase
RG42_RS08815	COG0457	Tetratricopeptide repeat
RG42_RS08820	COG3706	GGDEF domain
RG42_RS08825	COG2801	Transposase and inactivated derivatives
RG42_RS08860	COG3381	protein complex oligomerization
RG42_RS08870	COG1462	curli production assembly transport component CsgG
RG42_RS08885	COG2197	response regulator
RG42_RS08920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RG42_RS08925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RG42_RS08940	COG2943	transferase activity, transferring hexosyl groups
RG42_RS08945	COG5645	(Lipo)protein
RG42_RS08965	COG1560	Kdo2-lipid A biosynthetic process
RG42_RS08975	COG2353	YceI-like domain
RG42_RS08980	COG3038	cytochrome b561
RG42_RS09020	COG2999	glutathione oxidoreductase activity
RG42_RS09030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG42_RS09040	COG0673	inositol 2-dehydrogenase activity
RG42_RS09045	COG0728	peptidoglycan biosynthetic process
RG42_RS09050	COG3418	PFAM FlgN family protein
RG42_RS09055	COG2747	anti-sigma28 factor FlgM
RG42_RS09060	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
RG42_RS09065	COG1815	bacterial-type flagellum-dependent cell motility
RG42_RS09070	COG1558	bacterial-type flagellum-dependent cell motility
RG42_RS09075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RG42_RS09080	COG1749	Flagellar hook protein flgE
RG42_RS09085	COG4787	bacterial-type flagellum-dependent cell motility
RG42_RS09090	COG4786	Flagellar basal body rod
RG42_RS09105	COG1705	Flagellar rod assembly protein muramidase FlgJ
RG42_RS09105	COG3951	Flagellar rod assembly protein muramidase FlgJ
RG42_RS09110	COG1256	bacterial-type flagellum assembly
RG42_RS09115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RG42_RS09120	COG1530	ribonuclease E activity
RG42_RS09130	COG0564	pseudouridine synthase activity
RG42_RS09135	COG0424	maF-like protein
RG42_RS09140	COG1399	metal-binding, possibly nucleic acid-binding protein
RG42_RS09160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RG42_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS09175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RG42_RS09180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RG42_RS09185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RG42_RS09195	COG0470	DNA polymerase III
RG42_RS09200	COG0084	hydrolase, TatD family'
RG42_RS09205	COG1263	PTS System
RG42_RS09205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS09210	COG4773	Receptor
RG42_RS09215	COG0537	adenosine 5'-monophosphoramidase activity
RG42_RS09220	COG5633	Lipoprotein
RG42_RS09225	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
RG42_RS09250	COG1252	NADH dehydrogenase
RG42_RS09260	COG3134	Outer membrane lipoprotein
RG42_RS09265	COG1309	transcriptional regulator
RG42_RS09275	COG1376	ErfK ybiS ycfS ynhG family protein
RG42_RS09275	COG1388	LysM domain
RG42_RS09280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RG42_RS09285	COG4763	Acyl-transferase
RG42_RS09290	COG4591	ABC-type transport system involved in lipoprotein release permease component
RG42_RS09295	COG1136	(ABC) transporter
RG42_RS09300	COG4591	ABC-type transport system involved in lipoprotein release permease component
RG42_RS09310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RG42_RS09315	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RG42_RS09325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RG42_RS09330	COG1177	transmembrane transport
RG42_RS09340	COG3842	ATPase activity
RG42_RS09355	COG2850	peptidyl-arginine hydroxylation
RG42_RS09360	COG2205	protein histidine kinase activity
RG42_RS09365	COG0745	RESPONSE REGULATOR receiver
RG42_RS09370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RG42_RS09390	COG1187	pseudouridine synthase activity
RG42_RS09395	COG0538	isocitrate dehydrogenase activity
RG42_RS09430	COG5562	phage envelope protein
RG42_RS09435	COG0789	Transcriptional regulator
RG42_RS09440	COG2200	EAL domain
RG42_RS09465	COG2200	EAL domain
RG42_RS09525	COG2894	cell division
RG42_RS09560	COG0179	Fumarylacetoacetate (FAA) hydrolase
RG42_RS09575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RG42_RS09580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RG42_RS09585	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RG42_RS09600	COG2719	SpoVR family
RG42_RS09610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RG42_RS09620	COG1619	proteins homologs of microcin C7 resistance protein MccF
RG42_RS09635	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RG42_RS09640	COG2261	transglycosylase associated protein
RG42_RS09660	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RG42_RS09660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS09660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG42_RS09665	COG1461	Dihydroxyacetone kinase
RG42_RS09670	COG2376	Dihydroxyacetone kinase
RG42_RS09675	COG3284	Transcriptional regulator
RG42_RS09680	COG3468	outer membrane autotransporter barrel domain protein
RG42_RS09695	COG0012	GTP binding
RG42_RS09710	COG0659	secondary active sulfate transmembrane transporter activity
RG42_RS09715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RG42_RS09740	COG2890	protein-(glutamine-N5) methyltransferase activity
RG42_RS09745	COG3094	Invasion gene expression up-regulator, SirB
RG42_RS09750	COG2912	Transglutaminase-like superfamily
RG42_RS09790	COG0387	Pfam Sodium calcium exchanger
RG42_RS09795	COG4572	Cation transport regulator
RG42_RS09800	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RG42_RS09805	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
RG42_RS09810	COG4932	domain protein
RG42_RS09815	COG2197	response regulator
RG42_RS09820	COG3850	Histidine kinase
RG42_RS09830	COG2223	nitrite transmembrane transporter activity
RG42_RS09835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RG42_RS09840	COG1140	nitrate reductase beta subunit
RG42_RS09845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RG42_RS09850	COG2181	nitrate reductase activity
RG42_RS09885	COG0788	formyltetrahydrofolate deformylase activity
RG42_RS09895	COG1752	Esterase of the alpha-beta hydrolase superfamily
RG42_RS09900	COG0745	RESPONSE REGULATOR receiver
RG42_RS09905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RG42_RS09915	COG1435	thymidine kinase activity
RG42_RS09935	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS09935	COG1454	alcohol dehydrogenase
RG42_RS09940	COG2095	MarC family integral membrane protein
RG42_RS09950	COG4166	transmembrane transport
RG42_RS09955	COG0601	transmembrane transport
RG42_RS09960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG42_RS09965	COG0444	Belongs to the ABC transporter superfamily
RG42_RS09970	COG4608	Belongs to the ABC transporter superfamily
RG42_RS09990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RG42_RS09995	COG2350	Protein conserved in bacteria
RG42_RS10000	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
RG42_RS10005	COG1607	acyl-coa hydrolase
RG42_RS10065	COG2135	peptidase activity
RG42_RS10080	COG3047	cAMP biosynthetic process
RG42_RS10085	COG3685	Protein conserved in bacteria
RG42_RS10090	COG3685	Protein conserved in bacteria
RG42_RS10095	COG3729	General stress protein
RG42_RS10110	COG0135	phosphoribosylanthranilate isomerase activity
RG42_RS10110	COG0134	indole-3-glycerol-phosphate synthase activity
RG42_RS10115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RG42_RS10115	COG0512	Glutamine amidotransferase of anthranilate synthase
RG42_RS10120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RG42_RS10130	COG0613	PHP domain protein
RG42_RS10135	COG0009	L-threonylcarbamoyladenylate synthase
RG42_RS10140	COG4907	membrane protein (DUF2207)
RG42_RS10145	COG1187	pseudouridine synthase activity
RG42_RS10150	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
RG42_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS10165	COG0616	signal peptide processing
RG42_RS10175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RG42_RS10185	COG0583	DNA-binding transcription factor activity
RG42_RS10205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RG42_RS10215	COG0671	phosphoesterase, PA-phosphatase related
RG42_RS10220	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
RG42_RS10225	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RG42_RS10235	COG0023	Translation Initiation Factor
RG42_RS10245	COG1349	DNA-binding transcription factor activity
RG42_RS10255	COG5001	Diguanylate cyclase
RG42_RS10270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RG42_RS10270	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RG42_RS10275	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RG42_RS10280	COG2852	Protein conserved in bacteria
RG42_RS10290	COG4172	Belongs to the ABC transporter superfamily
RG42_RS10295	COG4171	peptide transport system, permease
RG42_RS10300	COG4168	peptide transport system, permease
RG42_RS10305	COG4166	transmembrane transport
RG42_RS10320	COG0531	amino acid
RG42_RS10325	COG0174	glutamine synthetase
RG42_RS10330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RG42_RS10335	COG1917	Cupin 2, conserved barrel domain protein
RG42_RS10335	COG1396	sequence-specific DNA binding
RG42_RS10345	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS10350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RG42_RS10355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RG42_RS10360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RG42_RS10365	COG1842	Phage shock protein A
RG42_RS10375	COG1983	PspC domain protein
RG42_RS10385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RG42_RS10390	COG0366	Alpha amylase catalytic
RG42_RS10395	COG1653	transport
RG42_RS10400	COG1175	transmembrane transport
RG42_RS10405	COG0395	ABC-type sugar transport system, permease component
RG42_RS10410	COG1063	alcohol dehydrogenase
RG42_RS10415	COG1082	Xylose isomerase domain protein TIM barrel
RG42_RS10420	COG0673	inositol 2-dehydrogenase activity
RG42_RS10430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG42_RS10435	COG3842	ATPase activity
RG42_RS10445	COG1609	Transcriptional regulator
RG42_RS10450	COG3106	COG3106 Predicted ATPase
RG42_RS10460	COG3283	Transcriptional regulator of aromatic amino acids metabolism
RG42_RS10465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RG42_RS10470	COG4948	Mandelate Racemase Muconate Lactonizing
RG42_RS10475	COG2866	Carboxypeptidase
RG42_RS10480	COG0702	epimerase
RG42_RS10485	COG1073	alpha beta
RG42_RS10490	COG0583	DNA-binding transcription factor activity
RG42_RS10500	COG4166	transmembrane transport
RG42_RS10505	COG0668	transmembrane transport
RG42_RS10510	COG3182	Iron-regulated membrane protein
RG42_RS10515	COG0589	response to stress
RG42_RS10520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RG42_RS10525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RG42_RS10530	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RG42_RS10540	COG1473	amidohydrolase
RG42_RS10545	COG1473	amidohydrolase
RG42_RS10550	COG0583	DNA-binding transcription factor activity
RG42_RS10560	COG2840	Smr protein MutS2
RG42_RS10565	COG3706	GGDEF domain
RG42_RS10580	COG0513	Belongs to the DEAD box helicase family
RG42_RS10590	COG0582	viral genome integration into host DNA
RG42_RS10610	COG3723	Recombinational DNA repair protein, rece pathway
RG42_RS10615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG42_RS10660	COG4197	protein conserved in bacteria, prophage-related
RG42_RS10670	COG3756	Protein conserved in bacteria
RG42_RS10675	COG1484	DNA-dependent DNA replication
RG42_RS10680	COG1846	Transcriptional regulator
RG42_RS10710	COG3385	transposase activity
RG42_RS10735	COG3064	Membrane
RG42_RS10750	COG3772	lysozyme
RG42_RS10760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RG42_RS10770	COG1475	DNA binding
RG42_RS10805	COG3436	PFAM IS66 Orf2 family protein
RG42_RS10810	COG4372	Transposase
RG42_RS10835	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RG42_RS10840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RG42_RS10850	COG0589	response to stress
RG42_RS10855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG42_RS10860	COG1013	pyruvate-flavodoxin oxidoreductase activity
RG42_RS10860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG42_RS10860	COG0674	pyruvate-flavodoxin oxidoreductase activity
RG42_RS10860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RG42_RS10865	COG3042	response to heat
RG42_RS10870	COG3187	Heat shock protein
RG42_RS10875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RG42_RS10880	COG2911	Protein conserved in bacteria
RG42_RS10890	COG3784	Protein of unknown function (DUF1318)
RG42_RS10895	COG2207	Transcriptional regulator
RG42_RS10900	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS10905	COG3733	amine oxidase
RG42_RS10910	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS10910	COG2030	dehydratase
RG42_RS10915	COG3396	Phenylacetate-CoA oxygenase
RG42_RS10920	COG3460	Phenylacetate-CoA oxygenase
RG42_RS10925	COG3396	Phenylacetate-CoA oxygenase
RG42_RS10930	COG2151	metal-sulfur cluster biosynthetic enzyme
RG42_RS10935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG42_RS10940	COG1024	Enoyl-CoA hydratase
RG42_RS10945	COG1024	Enoyl-CoA hydratase
RG42_RS10950	COG1250	3-hydroxyacyl-CoA dehydrogenase
RG42_RS10955	COG2050	protein possibly involved in aromatic compounds catabolism
RG42_RS10960	COG0183	Belongs to the thiolase family
RG42_RS10965	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RG42_RS10970	COG3327	negative regulation of DNA-templated transcription, initiation
RG42_RS10975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RG42_RS10985	COG0667	Aldo Keto reductase
RG42_RS10995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RG42_RS11005	COG2267	carboxylic ester hydrolase activity
RG42_RS11010	COG2453	phosphatase
RG42_RS11010	COG0671	phosphoesterase, PA-phosphatase related
RG42_RS11020	COG1643	Atp-dependent helicase
RG42_RS11025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RG42_RS11030	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS11035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RG42_RS11040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RG42_RS11045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RG42_RS11050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RG42_RS11055	COG3038	cytochrome b561
RG42_RS11070	COG0840	transmembrane signaling receptor activity
RG42_RS11075	COG0583	DNA-binding transcription factor activity
RG42_RS11080	COG5383	Protein conserved in bacteria
RG42_RS11100	COG2841	Protein conserved in bacteria
RG42_RS11105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG42_RS11110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RG42_RS11115	COG1275	C4-dicarboxylate transporter malic acid transport protein
RG42_RS11120	COG0500	methyltransferase
RG42_RS11135	COG0675	Transposase, IS605 OrfB family
RG42_RS11140	COG3135	benzoate transporter
RG42_RS11145	COG1396	sequence-specific DNA binding
RG42_RS11150	COG0826	peptidase U32
RG42_RS11160	COG1724	mRNA binding
RG42_RS11165	COG1598	PFAM Uncharacterised protein family UPF0150
RG42_RS11170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RG42_RS11175	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RG42_RS11180	COG3842	ATPase activity
RG42_RS11185	COG1176	ABC-type spermidine putrescine transport system, permease component I
RG42_RS11190	COG1177	transmembrane transport
RG42_RS11220	COG3238	Protein conserved in bacteria
RG42_RS11225	COG1247	-acetyltransferase
RG42_RS11235	COG2130	NADP-dependent
RG42_RS11240	COG1802	Transcriptional regulator
RG42_RS11245	COG4772	TonB-dependent receptor
RG42_RS11260	COG3391	amine dehydrogenase activity
RG42_RS11265	COG1113	amino acid transport
RG42_RS11270	COG0625	glutathione transferase activity
RG42_RS11285	COG3209	COG3209 Rhs family protein
RG42_RS11295	COG5433	transposase activity
RG42_RS11300	COG5433	transposase activity
RG42_RS11310	COG5433	transposase activity
RG42_RS11320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RG42_RS11325	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RG42_RS11330	COG0384	phenazine biosynthesis protein PhzF
RG42_RS11335	COG2181	nitrate reductase activity
RG42_RS11340	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RG42_RS11345	COG1140	nitrate reductase beta subunit
RG42_RS11350	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RG42_RS11355	COG2223	nitrite transmembrane transporter activity
RG42_RS11360	COG4886	Leucine-rich repeat (LRR) protein
RG42_RS11365	COG4886	Leucine-rich repeat (LRR) protein
RG42_RS11370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG42_RS11375	COG0697	spore germination
RG42_RS11380	COG3383	formate dehydrogenase (NAD+) activity
RG42_RS11380	COG0243	molybdopterin cofactor binding
RG42_RS11385	COG3383	formate dehydrogenase (NAD+) activity
RG42_RS11385	COG0243	molybdopterin cofactor binding
RG42_RS11390	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS11395	COG2864	formate dehydrogenase
RG42_RS11405	COG3093	addiction module antidote protein HigA
RG42_RS11410	COG1064	alcohol dehydrogenase
RG42_RS11435	COG1764	response to oxidative stress
RG42_RS11440	COG4608	Belongs to the ABC transporter superfamily
RG42_RS11445	COG0444	Belongs to the ABC transporter superfamily
RG42_RS11450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG42_RS11455	COG0601	transmembrane transport
RG42_RS11460	COG0747	negative chemotaxis
RG42_RS11465	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RG42_RS11470	COG2200	EAL domain
RG42_RS11470	COG2202	Pas domain
RG42_RS11470	COG2199	diguanylate cyclase activity
RG42_RS11475	COG3706	GGDEF domain
RG42_RS11480	COG1649	PFAM Uncharacterised BCR, COG1649
RG42_RS11485	COG0531	amino acid
RG42_RS11490	COG0076	glutamate decarboxylase activity
RG42_RS11505	COG0612	Peptidase, M16
RG42_RS11510	COG4771	TonB-dependent receptor
RG42_RS11515	COG4178	(ABC) transporter
RG42_RS11520	COG0641	radical SAM
RG42_RS11525	COG3119	arylsulfatase activity
RG42_RS11530	COG2207	Transcriptional regulator
RG42_RS11540	COG0243	molybdopterin cofactor binding
RG42_RS11545	COG3539	Fimbrial protein
RG42_RS11550	COG3539	Fimbrial protein
RG42_RS11555	COG3539	Fimbrial protein
RG42_RS11560	COG3188	usher protein
RG42_RS11565	COG4977	sequence-specific DNA binding
RG42_RS11575	COG3550	peptidyl-serine autophosphorylation
RG42_RS11580	COG1396	sequence-specific DNA binding
RG42_RS11590	COG2911	Protein conserved in bacteria
RG42_RS11590	COG3210	domain, Protein
RG42_RS11640	COG3781	membrane
RG42_RS11660	COG2199	diguanylate cyclase activity
RG42_RS11670	COG2066	Belongs to the glutaminase family
RG42_RS11675	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS11680	COG0583	DNA-binding transcription factor activity
RG42_RS11705	COG1846	Transcriptional regulator
RG42_RS11710	COG4977	sequence-specific DNA binding
RG42_RS11720	COG0697	spore germination
RG42_RS11725	COG2814	Major facilitator Superfamily
RG42_RS11735	COG3706	GGDEF domain
RG42_RS11740	COG3111	PFAM Bacterial OB fold (BOF) protein
RG42_RS11745	COG1546	Belongs to the CinA family
RG42_RS11750	COG0339	signal peptide processing
RG42_RS11760	COG4221	oxidoreductase activity
RG42_RS11765	COG1802	Transcriptional regulator
RG42_RS11775	COG0246	Mannitol dehydrogenase
RG42_RS11780	COG0477	Major facilitator Superfamily
RG42_RS11785	COG1063	alcohol dehydrogenase
RG42_RS11790	COG4948	Mandelate Racemase Muconate Lactonizing
RG42_RS11805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG42_RS11820	COG0243	molybdopterin cofactor binding
RG42_RS11835	COG0243	molybdopterin cofactor binding
RG42_RS11840	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS11845	COG3302	dmso reductase anchor subunit
RG42_RS11850	COG3381	protein complex oligomerization
RG42_RS11860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RG42_RS11865	COG1940	carbohydrate kinase activity
RG42_RS11870	COG0583	DNA-binding transcription factor activity
RG42_RS11875	COG2814	Major facilitator Superfamily
RG42_RS11895	COG3591	Belongs to the peptidase S1B family
RG42_RS11910	COG0628	permease
RG42_RS11915	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RG42_RS11920	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RG42_RS11935	COG0531	amino acid
RG42_RS11945	COG3136	membrane protein required for alginate biosynthesis
RG42_RS11950	COG0745	RESPONSE REGULATOR receiver
RG42_RS11955	COG2205	protein histidine kinase activity
RG42_RS11965	COG0114	fumarate hydratase activity
RG42_RS11970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RG42_RS11970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RG42_RS11975	COG1482	cell wall glycoprotein biosynthetic process
RG42_RS11980	COG5339	Protein conserved in bacteria
RG42_RS11995	COG3250	beta-galactosidase activity
RG42_RS12000	COG1309	transcriptional regulator
RG42_RS12005	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS12010	COG1609	Transcriptional regulator
RG42_RS12015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS12015	COG1263	PTS System
RG42_RS12020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RG42_RS12030	COG0673	inositol 2-dehydrogenase activity
RG42_RS12075	COG4659	FMN binding
RG42_RS12085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RG42_RS12095	COG3104	oligopeptide transport
RG42_RS12100	COG0625	glutathione transferase activity
RG42_RS12105	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RG42_RS12120	COG3895	Periplasmic Protein
RG42_RS12130	COG3133	Outer membrane lipoprotein
RG42_RS12145	COG1566	PFAM secretion protein HlyD family protein
RG42_RS12150	COG1289	transmembrane transporter activity
RG42_RS12155	COG2032	superoxide dismutase activity
RG42_RS12160	COG4989	oxidoreductase activity
RG42_RS12165	COG3313	Fe-S protein
RG42_RS12170	COG1309	transcriptional regulator
RG42_RS12175	COG1902	pentaerythritol trinitrate reductase activity
RG42_RS12180	COG0346	lactoylglutathione lyase activity
RG42_RS12185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG42_RS12190	COG1201	RNA secondary structure unwinding
RG42_RS12195	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RG42_RS12200	COG0791	NLP P60 protein
RG42_RS12205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RG42_RS12210	COG2814	Major facilitator Superfamily
RG42_RS12230	COG0583	DNA-binding transcription factor activity
RG42_RS12235	COG2814	Major facilitator Superfamily
RG42_RS12240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RG42_RS12245	COG0307	riboflavin synthase, alpha
RG42_RS12255	COG3468	outer membrane autotransporter barrel domain protein
RG42_RS12275	COG4529	Protein conserved in bacteria
RG42_RS12285	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
RG42_RS12290	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS12300	COG2414	aldehyde ferredoxin oxidoreductase
RG42_RS12305	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS12315	COG0469	pyruvate kinase activity
RG42_RS12320	COG4238	major outer membrane lipoprotein
RG42_RS12325	COG1376	ErfK ybiS ycfS ynhG family protein
RG42_RS12340	COG0719	Fe-S assembly protein
RG42_RS12345	COG0396	ATPase activity
RG42_RS12350	COG0719	Fe-S assembly protein
RG42_RS12355	COG0316	Belongs to the HesB IscA family
RG42_RS12365	COG2050	protein possibly involved in aromatic compounds catabolism
RG42_RS12370	COG0277	FAD linked oxidase domain protein
RG42_RS12370	COG0247	lactate metabolic process
RG42_RS12380	COG0628	permease
RG42_RS12395	COG0738	Major facilitator superfamily
RG42_RS12400	COG2271	Major facilitator Superfamily
RG42_RS12415	COG4670	ketone body catabolic process
RG42_RS12420	COG1960	acyl-CoA dehydrogenase activity
RG42_RS12425	COG1960	acyl-CoA dehydrogenase activity
RG42_RS12430	COG2207	Transcriptional regulator
RG42_RS12430	COG1917	Cupin 2, conserved barrel domain protein
RG42_RS12440	COG2086	electron transfer activity
RG42_RS12445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RG42_RS12450	COG0644	oxidoreductase
RG42_RS12455	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RG42_RS12460	COG0318	PFAM AMP-dependent synthetase and ligase
RG42_RS12465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG42_RS12465	COG0574	Belongs to the PEP-utilizing enzyme family
RG42_RS12475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RG42_RS12480	COG4256	Hemin uptake protein
RG42_RS12490	COG2200	EAL domain
RG42_RS12495	COG0791	NLP P60 protein
RG42_RS12505	COG0386	Belongs to the glutathione peroxidase family
RG42_RS12520	COG0072	phenylalanine-tRNA ligase activity
RG42_RS12520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RG42_RS12580	COG3137	Salt-induced outer membrane protein
RG42_RS12585	COG1105	Belongs to the carbohydrate kinase PfkB family
RG42_RS12595	COG3001	Fructosamine kinase
RG42_RS12605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG42_RS12610	COG1988	membrane-bound metal-dependent
RG42_RS12615	COG1823	symporter activity
RG42_RS12630	COG0753	catalase activity
RG42_RS12645	COG1486	melibiose metabolic process
RG42_RS12650	COG2169	Transcriptional regulator
RG42_RS12650	COG1917	Cupin 2, conserved barrel domain protein
RG42_RS12655	COG1447	Phosphotransferase system cellobiose-specific component IIA
RG42_RS12660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RG42_RS12665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RG42_RS12675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG42_RS12685	COG0322	excinuclease ABC activity
RG42_RS12695	COG3678	ATP-independent chaperone mediated protein folding
RG42_RS12730	COG0708	Exodeoxyribonuclease III
RG42_RS12735	COG0398	Pfam SNARE associated Golgi protein
RG42_RS12745	COG0398	Pfam SNARE associated Golgi protein
RG42_RS12750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RG42_RS12755	COG4134	Bacterial extracellular solute-binding protein
RG42_RS12760	COG4135	transport system, permease component
RG42_RS12765	COG4136	ATPase activity
RG42_RS12770	COG2897	thiosulfate sulfurtransferase activity
RG42_RS12775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RG42_RS12780	COG0494	nUDIX hydrolase
RG42_RS12790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RG42_RS12810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RG42_RS12825	COG0778	Nitroreductase
RG42_RS12830	COG0616	signal peptide processing
RG42_RS12835	COG0252	asparaginase activity
RG42_RS12840	COG1335	isochorismatase
RG42_RS12845	COG2814	Major facilitator Superfamily
RG42_RS12850	COG1349	DNA-binding transcription factor activity
RG42_RS12855	COG0667	Aldo Keto reductase
RG42_RS12860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS12865	COG0191	fructose-bisphosphate aldolase activity
RG42_RS12870	COG1063	alcohol dehydrogenase
RG42_RS12875	COG2271	Major facilitator Superfamily
RG42_RS12880	COG1063	alcohol dehydrogenase
RG42_RS12885	COG3139	Protein of unknown function (DUF1315)
RG42_RS12895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RG42_RS12900	COG0676	glucose-6-phosphate 1-epimerase activity
RG42_RS12905	COG0656	L-ascorbic acid biosynthetic process
RG42_RS12910	COG3713	MltA-interacting MipA family protein
RG42_RS12915	COG2766	serine protein kinase
RG42_RS12925	COG2199	diguanylate cyclase activity
RG42_RS12930	COG2199	diguanylate cyclase activity
RG42_RS12935	COG2199	diguanylate cyclase activity
RG42_RS12940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RG42_RS12955	COG2207	Transcriptional regulator
RG42_RS12960	COG2807	transmembrane transport
RG42_RS12965	COG3189	MarR family transcriptional regulator
RG42_RS12970	COG3042	response to heat
RG42_RS12975	COG2199	diguanylate cyclase activity
RG42_RS12975	COG2203	Gaf domain
RG42_RS12990	COG2261	transglycosylase associated protein
RG42_RS13000	COG3615	Tellurite resistance protein tehB
RG42_RS13010	COG0583	DNA-binding transcription factor activity
RG42_RS13015	COG0473	3-isopropylmalate dehydrogenase activity
RG42_RS13020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RG42_RS13025	COG4638	Rieske (2fe-2S)
RG42_RS13030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG42_RS13035	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RG42_RS13040	COG0318	PFAM AMP-dependent synthetase and ligase
RG42_RS13045	COG3065	identical protein binding
RG42_RS13050	COG1214	PFAM Peptidase M22, glycoprotease
RG42_RS13055	COG1199	ATP-dependent helicase activity
RG42_RS13060	COG0251	oxidation-reduction process
RG42_RS13075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RG42_RS13085	COG1760	l-serine dehydratase
RG42_RS13090	COG2200	EAL domain
RG42_RS13095	COG1253	flavin adenine dinucleotide binding
RG42_RS13110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS13110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS13115	COG3715	PTS system
RG42_RS13120	COG3716	PTS system mannose fructose sorbose family IID component
RG42_RS13140	COG2226	methyltransferase
RG42_RS13175	COG1414	Transcriptional regulator
RG42_RS13180	COG2814	Major facilitator Superfamily
RG42_RS13190	COG0793	Belongs to the peptidase S41A family
RG42_RS13200	COG1956	GAF domain-containing protein
RG42_RS13205	COG2995	paraquat-inducible protein a
RG42_RS13210	COG3008	intermembrane lipid transfer
RG42_RS13230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RG42_RS13245	COG1276	copper resistance
RG42_RS13250	COG2372	response to copper ion
RG42_RS13260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RG42_RS13265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG42_RS13270	COG1770	oligopeptidase
RG42_RS13280	COG2979	Protein of unknown function (DUF533)
RG42_RS13300	COG3141	response to X-ray
RG42_RS13310	COG0800	Aldolase
RG42_RS13315	COG0129	dihydroxy-acid dehydratase activity
RG42_RS13320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RG42_RS13335	COG1737	Transcriptional regulator
RG42_RS13340	COG0469	pyruvate kinase activity
RG42_RS13345	COG1560	Kdo2-lipid A biosynthetic process
RG42_RS13350	COG0739	heme binding
RG42_RS13355	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
RG42_RS13365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RG42_RS13395	COG0217	transcriptional regulatory protein
RG42_RS13400	COG0494	nUDIX hydrolase
RG42_RS13410	COG1335	isochorismatase
RG42_RS13415	COG1801	Protein of unknown function DUF72
RG42_RS13420	COG3788	relative of glutathione S-transferase, MAPEG superfamily
RG42_RS13435	COG0243	molybdopterin cofactor binding
RG42_RS13440	COG3005	denitrification pathway
RG42_RS13450	COG3102	Protein conserved in bacteria
RG42_RS13465	COG3755	Protein conserved in bacteria
RG42_RS13475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RG42_RS13480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RG42_RS13485	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
RG42_RS13490	COG0745	RESPONSE REGULATOR receiver
RG42_RS13495	COG2201	protein-glutamate methylesterase activity
RG42_RS13500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RG42_RS13505	COG0840	transmembrane signaling receptor activity
RG42_RS13510	COG0840	transmembrane signaling receptor activity
RG42_RS13515	COG0835	chemotaxis
RG42_RS13520	COG0643	Histidine kinase
RG42_RS13520	COG2198	Histidine kinase
RG42_RS13525	COG1360	Flagellar Motor Protein
RG42_RS13530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RG42_RS13550	COG0589	response to stress
RG42_RS13560	COG1877	trehalose-phosphatase activity
RG42_RS13565	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG42_RS13575	COG1879	ABC-type sugar transport system periplasmic component
RG42_RS13585	COG1528	Iron-storage protein
RG42_RS13605	COG1528	Iron-storage protein
RG42_RS13615	COG0814	amino acid
RG42_RS13620	COG3318	Belongs to the UPF0149 family
RG42_RS13620	COG3012	SEC-C Motif Domain Protein
RG42_RS13650	COG2197	response regulator
RG42_RS13665	COG2197	response regulator
RG42_RS13670	COG1126	abc transporter atp-binding protein
RG42_RS13675	COG0765	amino acid transport
RG42_RS13685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS13695	COG1191	sigma factor activity
RG42_RS13700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RG42_RS13730	COG0366	Alpha amylase catalytic
RG42_RS13745	COG2391	methyltransferase activity
RG42_RS13750	COG0425	Belongs to the sulfur carrier protein TusA family
RG42_RS13755	COG2135	peptidase activity
RG42_RS13770	COG1766	The M ring may be actively involved in energy transduction
RG42_RS13775	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RG42_RS13780	COG1317	bacterial-type flagellum organization
RG42_RS13785	COG1157	protein secretion by the type III secretion system
RG42_RS13790	COG2882	bacterial-type flagellum organization
RG42_RS13795	COG3144	bacterial-type flagellum assembly
RG42_RS13800	COG1580	Controls the rotational direction of flagella during chemotaxis
RG42_RS13805	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RG42_RS13810	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RG42_RS13815	COG3190	flagellar
RG42_RS13820	COG1338	Plays a role in the flagellum-specific transport system
RG42_RS13825	COG1987	bacterial-type flagellum assembly
RG42_RS13830	COG1684	flagellar biosynthetic protein fliR
RG42_RS13835	COG2197	response regulator
RG42_RS13860	COG3706	GGDEF domain
RG42_RS13870	COG5475	Uncharacterized small protein (DUF2158)
RG42_RS13875	COG2354	Protein conserved in bacteria
RG42_RS13880	COG0697	spore germination
RG42_RS13885	COG3727	T/G mismatch-specific endonuclease activity
RG42_RS13890	COG0270	DNA (cytosine-5-)-methyltransferase activity
RG42_RS13895	COG1418	mRNA catabolic process
RG42_RS13910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG42_RS13925	COG2205	protein histidine kinase activity
RG42_RS13930	COG0745	RESPONSE REGULATOR receiver
RG42_RS13935	COG2351	hydroxyisourate hydrolase activity
RG42_RS13950	COG3443	Belongs to the bacterial solute-binding protein 9 family
RG42_RS13955	COG3038	cytochrome b561
RG42_RS13980	COG1388	LysM domain
RG42_RS13980	COG1470	cell adhesion involved in biofilm formation
RG42_RS14005	COG1470	cell adhesion involved in biofilm formation
RG42_RS14005	COG1388	LysM domain
RG42_RS14015	COG3436	PFAM IS66 Orf2 family protein
RG42_RS14020	COG4372	Transposase
RG42_RS14030	COG0477	Major facilitator Superfamily
RG42_RS14035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RG42_RS14040	COG0217	transcriptional regulatory protein
RG42_RS14055	COG0534	Mate efflux family protein
RG42_RS14065	COG0582	viral genome integration into host DNA
RG42_RS14110	COG3209	COG3209 Rhs family protein
RG42_RS14125	COG0583	DNA-binding transcription factor activity
RG42_RS14130	COG0583	DNA-binding transcription factor activity
RG42_RS14140	COG1376	ErfK ybiS ycfS ynhG family protein
RG42_RS14155	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
RG42_RS14215	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RG42_RS14230	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RG42_RS14245	COG1454	alcohol dehydrogenase
RG42_RS14245	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS14250	COG4656	Part of a membrane complex involved in electron transport
RG42_RS14275	COG1289	transmembrane transporter activity
RG42_RS14285	COG1686	Belongs to the peptidase S11 family
RG42_RS14345	COG2246	polysaccharide biosynthetic process
RG42_RS14365	COG0582	viral genome integration into host DNA
RG42_RS14370	COG2925	Exonuclease
RG42_RS14375	COG0425	Belongs to the sulfur carrier protein TusA family
RG42_RS14380	COG2391	methyltransferase activity
RG42_RS14385	COG0531	amino acid
RG42_RS14390	COG0583	DNA-binding transcription factor activity
RG42_RS14395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RG42_RS14400	COG4115	mRNA cleavage
RG42_RS14405	COG2161	toxin-antitoxin pair type II binding
RG42_RS14425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RG42_RS14435	COG0131	Imidazoleglycerol-phosphate dehydratase
RG42_RS14435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RG42_RS14440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RG42_RS14475	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RG42_RS14485	COG0562	UDP-galactopyranose mutase
RG42_RS14520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RG42_RS14525	COG1088	dTDP-glucose 4,6-dehydratase activity
RG42_RS14535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RG42_RS14545	COG0438	transferase activity, transferring glycosyl groups
RG42_RS14550	COG2327	Polysaccharide pyruvyl transferase
RG42_RS14555	COG2244	polysaccharide biosynthetic process
RG42_RS14560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RG42_RS14565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RG42_RS14570	COG0662	Cupin 2, conserved barrel domain protein
RG42_RS14570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
RG42_RS14575	COG0297	glycogen (starch) synthase activity
RG42_RS14580	COG1051	belongs to the nudix hydrolase family
RG42_RS14585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RG42_RS14590	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
RG42_RS14595	COG0110	maltose O-acetyltransferase activity
RG42_RS14600	COG1216	Glycosyl transferase, family 2
RG42_RS14610	COG0438	transferase activity, transferring glycosyl groups
RG42_RS14615	COG1045	serine acetyltransferase
RG42_RS14620	COG0463	Glycosyl transferase, family 2
RG42_RS14625	COG0489	protein tyrosine kinase activity
RG42_RS14625	COG3206	protein involved in exopolysaccharide biosynthesis
RG42_RS14630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RG42_RS14635	COG1596	polysaccharide export
RG42_RS14640	COG1253	flavin adenine dinucleotide binding
RG42_RS14650	COG2982	Protein involved in outer membrane biogenesis
RG42_RS14660	COG0572	uridine kinase
RG42_RS14665	COG5002	protein histidine kinase activity
RG42_RS14665	COG5001	Diguanylate cyclase
RG42_RS14665	COG3447	MASE1 domain protein
RG42_RS14670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RG42_RS14675	COG0443	Heat shock 70 kDa protein
RG42_RS14680	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
RG42_RS14685	COG3779	Protein conserved in bacteria
RG42_RS14690	COG0631	protein serine/threonine phosphatase activity
RG42_RS14695	COG4245	von Willebrand factor, type A
RG42_RS14730	COG2205	protein histidine kinase activity
RG42_RS14735	COG0745	RESPONSE REGULATOR receiver
RG42_RS14750	COG0826	peptidase U32
RG42_RS14770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG42_RS14780	COG1070	Carbohydrate kinase
RG42_RS14815	COG1830	Aldolase
RG42_RS14820	COG2211	Major facilitator Superfamily
RG42_RS14825	COG1397	ADP-ribosylglycohydrolase
RG42_RS14830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS14835	COG2188	Transcriptional regulator
RG42_RS14840	COG3757	hydrolase, family 25
RG42_RS14845	COG0351	phosphomethylpyrimidine kinase
RG42_RS14865	COG5455	response to cobalt ion
RG42_RS14870	COG3539	Fimbrial protein
RG42_RS14875	COG3188	usher protein
RG42_RS14880	COG3121	Chaperone
RG42_RS14885	COG3539	Fimbrial protein
RG42_RS14900	COG0489	protein tyrosine kinase activity
RG42_RS14915	COG3831	ATPase activity
RG42_RS14925	COG0714	Associated with various cellular activities
RG42_RS14930	COG2425	protein containing a von Willebrand factor type A (vWA) domain
RG42_RS14935	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RG42_RS14940	COG4715	Zinc finger, swim domain protein
RG42_RS14945	COG4808	Protein conserved in bacteria
RG42_RS14950	COG4807	Protein conserved in bacteria
RG42_RS14955	COG3279	Response regulator of the LytR AlgR family
RG42_RS14960	COG3275	phosphorelay sensor kinase activity
RG42_RS14965	COG0789	Transcriptional regulator
RG42_RS14975	COG1174	glycine betaine transport
RG42_RS14980	COG1125	glycine betaine transport
RG42_RS14985	COG1174	glycine betaine transport
RG42_RS14990	COG1732	Glycine betaine
RG42_RS14995	COG1472	Belongs to the glycosyl hydrolase 3 family
RG42_RS15000	COG0277	FAD linked oxidase domain protein
RG42_RS15005	COG1686	Belongs to the peptidase S11 family
RG42_RS15015	COG0586	Pfam SNARE associated Golgi protein
RG42_RS15020	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS15045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RG42_RS15055	COG1346	cytolysis
RG42_RS15065	COG2949	membrane
RG42_RS15075	COG0493	'glutamate synthase
RG42_RS15080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RG42_RS15080	COG0167	dihydroorotate dehydrogenase activity
RG42_RS15085	COG4211	Belongs to the binding-protein-dependent transport system permease family
RG42_RS15090	COG1129	ABC transporter
RG42_RS15095	COG1879	ABC-type sugar transport system periplasmic component
RG42_RS15100	COG1609	Transcriptional regulator
RG42_RS15110	COG2311	Membrane
RG42_RS15130	COG4771	TonB-dependent receptor
RG42_RS15135	COG0833	amino acid
RG42_RS15145	COG0583	DNA-binding transcription factor activity
RG42_RS15150	COG2855	membrane
RG42_RS15160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS15160	COG1522	sequence-specific DNA binding
RG42_RS15165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RG42_RS15180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RG42_RS15185	COG2313	pseudouridylate synthase activity
RG42_RS15190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS15195	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RG42_RS15195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS15195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS15200	COG1105	Belongs to the carbohydrate kinase PfkB family
RG42_RS15205	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS15205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS15210	COG2814	Major facilitator Superfamily
RG42_RS15225	COG0246	Mannitol dehydrogenase
RG42_RS15230	COG0523	cobalamin synthesis protein
RG42_RS15235	COG0671	phosphoesterase, PA-phosphatase related
RG42_RS15240	COG0791	NLP P60 protein
RG42_RS15245	COG2200	EAL domain
RG42_RS15250	COG4166	transmembrane transport
RG42_RS15255	COG4174	ABC transporter (Permease)
RG42_RS15260	COG4239	(ABC) transporter, permease
RG42_RS15265	COG4172	Belongs to the ABC transporter superfamily
RG42_RS15280	COG2814	Major facilitator Superfamily
RG42_RS15285	COG1187	pseudouridine synthase activity
RG42_RS15295	COG1061	Type III restriction enzyme res subunit
RG42_RS15315	COG3083	sulfuric ester hydrolase activity
RG42_RS15330	COG3468	outer membrane autotransporter barrel domain protein
RG42_RS15340	COG2197	response regulator
RG42_RS15345	COG4235	cytochrome complex assembly
RG42_RS15345	COG3088	subunit of a heme lyase
RG42_RS15350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RG42_RS15355	COG1138	Cytochrome C-type biogenesis protein
RG42_RS15365	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RG42_RS15370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RG42_RS15375	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RG42_RS15380	COG4133	protoheme IX ABC transporter activity
RG42_RS15385	COG3005	denitrification pathway
RG42_RS15390	COG3043	anaerobic respiration
RG42_RS15395	COG0348	domain, Protein
RG42_RS15400	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS15410	COG3062	negative regulation of establishment of protein localization
RG42_RS15415	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS15415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS15435	COG4615	Cyclic peptide transporter
RG42_RS15440	COG3145	DNA-N1-methyladenine dioxygenase activity
RG42_RS15445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RG42_RS15445	COG2169	Transcriptional regulator
RG42_RS15450	COG1477	protein flavinylation
RG42_RS15455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
RG42_RS15470	COG0642	Histidine kinase
RG42_RS15470	COG2198	Histidine kinase
RG42_RS15475	COG2197	response regulator
RG42_RS15485	COG2205	protein histidine kinase activity
RG42_RS15485	COG0784	Response regulator, receiver
RG42_RS15490	COG3852	Histidine kinase
RG42_RS15495	COG2204	response regulator
RG42_RS15500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RG42_RS15505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RG42_RS15510	COG2031	fatty acid transporter
RG42_RS15515	COG0183	Belongs to the thiolase family
RG42_RS15520	COG4676	Protein conserved in bacteria
RG42_RS15525	COG5445	Predicted secreted protein (DUF2300)
RG42_RS15530	COG2373	Large extracellular alpha-helical protein
RG42_RS15535	COG3234	Protein of unknown function (DUF1175)
RG42_RS15540	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
RG42_RS15545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RG42_RS15555	COG3468	outer membrane autotransporter barrel domain protein
RG42_RS15565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG42_RS15575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG42_RS15580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG42_RS15585	COG3642	lipopolysaccharide core region biosynthetic process
RG42_RS15595	COG3436	PFAM IS66 Orf2 family protein
RG42_RS15600	COG4372	Transposase
RG42_RS15610	COG0583	DNA-binding transcription factor activity
RG42_RS15615	COG0584	glycerophosphoryl diester phosphodiesterase
RG42_RS15620	COG2271	Major facilitator Superfamily
RG42_RS15625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RG42_RS15635	COG0247	lactate metabolic process
RG42_RS15640	COG5464	transposase or invertase
RG42_RS15655	COG2271	Major facilitator Superfamily
RG42_RS15665	COG1414	Transcriptional regulator
RG42_RS15730	COG0318	PFAM AMP-dependent synthetase and ligase
RG42_RS15740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RG42_RS15755	COG1169	isochorismate synthase
RG42_RS15760	COG4575	ribosome binding
RG42_RS15765	COG2153	protein acetylation
RG42_RS15775	COG5160	protein modification by small protein removal
RG42_RS15780	COG2304	oxidoreductase activity
RG42_RS15785	COG2234	aminopeptidase activity
RG42_RS15820	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG42_RS15825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RG42_RS15835	COG0839	Belongs to the complex I subunit 6 family
RG42_RS15850	COG1034	ATP synthesis coupled electron transport
RG42_RS15855	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RG42_RS15860	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RG42_RS15880	COG0583	DNA-binding transcription factor activity
RG42_RS15890	COG0436	Aminotransferase
RG42_RS15900	COG0490	domain, Protein
RG42_RS15900	COG0471	metal ion transport
RG42_RS15905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG42_RS15925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RG42_RS15930	COG0857	belongs to the CobB CobQ family
RG42_RS15930	COG0280	phosphate acetyltransferase
RG42_RS15935	COG1288	antiporter activity
RG42_RS15940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
RG42_RS15945	COG0622	Phosphoesterase
RG42_RS15950	COG0625	glutathione transferase activity
RG42_RS15955	COG0625	glutathione transferase activity
RG42_RS15960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RG42_RS15965	COG1090	epimerase
RG42_RS15970	COG5464	transposase or invertase
RG42_RS15975	COG4598	ABC transporter
RG42_RS15980	COG4160	amino acid transport
RG42_RS15985	COG4215	(ABC) transporter
RG42_RS15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS15995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS16000	COG0163	prenyltransferase activity
RG42_RS16005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RG42_RS16010	COG1286	toxin biosynthetic process
RG42_RS16015	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
RG42_RS16020	COG0285	dihydrofolate synthase activity
RG42_RS16030	COG0586	Pfam SNARE associated Golgi protein
RG42_RS16040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RG42_RS16055	COG2814	Major facilitator Superfamily
RG42_RS16065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RG42_RS16080	COG3101	peptidyl-lysine hydroxylation
RG42_RS16085	COG0730	response to heat
RG42_RS16100	COG2890	protein-(glutamine-N5) methyltransferase activity
RG42_RS16115	COG3539	Fimbrial protein
RG42_RS16120	COG3539	Fimbrial protein
RG42_RS16125	COG3539	Fimbrial protein
RG42_RS16130	COG3121	Chaperone
RG42_RS16135	COG3188	usher protein
RG42_RS16140	COG3539	Fimbrial protein
RG42_RS16145	COG2062	phosphohistidine phosphatase, SixA
RG42_RS16160	COG3691	Protein conserved in bacteria
RG42_RS16170	COG2067	long-chain fatty acid transport protein
RG42_RS16185	COG2853	Lipoprotein
RG42_RS16190	COG2116	formate transmembrane transporter activity
RG42_RS16200	COG0583	DNA-binding transcription factor activity
RG42_RS16205	COG2610	gluconate transmembrane transporter activity
RG42_RS16215	COG0477	Major facilitator Superfamily
RG42_RS16220	COG1566	PFAM secretion protein HlyD family protein
RG42_RS16225	COG2197	response regulator
RG42_RS16230	COG2198	Histidine kinase
RG42_RS16230	COG0784	Response regulator, receiver
RG42_RS16230	COG2205	protein histidine kinase activity
RG42_RS16230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS16235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RG42_RS16240	COG0679	Auxin Efflux Carrier
RG42_RS16245	COG0028	Belongs to the TPP enzyme family
RG42_RS16275	COG1560	Kdo2-lipid A biosynthetic process
RG42_RS16285	COG0436	Aminotransferase
RG42_RS16290	COG3275	phosphorelay sensor kinase activity
RG42_RS16295	COG3279	Response regulator of the LytR AlgR family
RG42_RS16300	COG2207	Transcriptional regulator
RG42_RS16305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG42_RS16305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS16305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS16310	COG1363	Peptidase, m42
RG42_RS16315	COG0006	proline dipeptidase activity
RG42_RS16320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS16325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS16355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RG42_RS16360	COG2200	EAL domain
RG42_RS16360	COG2199	diguanylate cyclase activity
RG42_RS16375	COG3415	Transposase
RG42_RS16380	COG3415	Transposase
RG42_RS16415	COG0583	DNA-binding transcription factor activity
RG42_RS16425	COG2211	Major facilitator Superfamily
RG42_RS16430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RG42_RS16440	COG0583	DNA-binding transcription factor activity
RG42_RS16445	COG0385	Bile acid
RG42_RS16450	COG3530	Putative quorum-sensing-regulated virulence factor
RG42_RS16475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RG42_RS16480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS16485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RG42_RS16490	COG2190	(PTS) system
RG42_RS16505	COG4884	unkown
RG42_RS16505	COG3831	ATPase activity
RG42_RS16510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RG42_RS16515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RG42_RS16520	COG4208	sulfate ABC transporter
RG42_RS16525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RG42_RS16530	COG4150	thiosulfate binding
RG42_RS16535	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS16550	COG1263	PTS System
RG42_RS16550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS16555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RG42_RS16560	COG2837	iron assimilation
RG42_RS16575	COG0456	acetyltransferase
RG42_RS16580	COG0860	N-Acetylmuramoyl-L-alanine amidase
RG42_RS16590	COG2207	Transcriptional regulator
RG42_RS16595	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RG42_RS16600	COG4816	utilization protein
RG42_RS16610	COG4303	Ethanolamine ammonia lyase large subunit
RG42_RS16615	COG4819	ethanolamine utilization protein
RG42_RS16620	COG3192	ethanolamine utilization protein
RG42_RS16625	COG1454	alcohol dehydrogenase
RG42_RS16630	COG4820	ethanolamine utilization protein (EutJ)
RG42_RS16635	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS16640	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RG42_RS16645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RG42_RS16650	COG0280	phosphate acetyltransferase
RG42_RS16655	COG4812	Cobalamin adenosyltransferase
RG42_RS16660	COG4766	ethanolamine catabolic process
RG42_RS16665	COG4917	ethanolamine utilization protein
RG42_RS16670	COG4810	utilization protein
RG42_RS16675	COG0280	phosphate acetyltransferase
RG42_RS16675	COG0281	malic enzyme
RG42_RS16680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RG42_RS16685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RG42_RS16690	COG5342	invasion associated locus B
RG42_RS16700	COG0493	'glutamate synthase
RG42_RS16700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS16705	COG3850	Histidine kinase
RG42_RS16710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG42_RS16720	COG1393	Belongs to the ArsC family
RG42_RS16735	COG0400	carboxylic ester hydrolase activity
RG42_RS16740	COG1444	tRNA N-acetyltransferase activity
RG42_RS16745	COG2321	neutral zinc metallopeptidase
RG42_RS16760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RG42_RS16770	COG2716	regulation of RNA biosynthetic process
RG42_RS16775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RG42_RS16780	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS16785	COG0651	ATP synthesis coupled electron transport
RG42_RS16790	COG0650	Formate hydrogenlyase subunit 4
RG42_RS16795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RG42_RS16800	COG4237	Hydrogenase 4 membrane
RG42_RS16805	COG0651	ATP synthesis coupled electron transport
RG42_RS16810	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
RG42_RS16810	COG3261	NADH dehydrogenase
RG42_RS16815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG42_RS16820	COG3260	NADH ubiquinone oxidoreductase 20
RG42_RS16830	COG3604	Transcriptional regulator
RG42_RS16835	COG2116	formate transmembrane transporter activity
RG42_RS16840	COG0628	permease
RG42_RS16845	COG4783	chaperone-mediated protein folding
RG42_RS16850	COG1393	Belongs to the ArsC family
RG42_RS16860	COG2233	PERMEase
RG42_RS16880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RG42_RS16885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RG42_RS16890	COG0248	Ppx GppA phosphatase
RG42_RS16895	COG2200	EAL domain
RG42_RS16915	COG3133	Outer membrane lipoprotein
RG42_RS16930	COG0516	GMP reductase activity
RG42_RS16930	COG0517	IMP dehydrogenase activity
RG42_RS16940	COG1645	bacterial-type flagellum-dependent swarming motility
RG42_RS16955	COG2976	Protein conserved in bacteria
RG42_RS16985	COG4953	penicillin-binding protein 1C
RG42_RS16990	COG2373	Large extracellular alpha-helical protein
RG42_RS16995	COG2897	thiosulfate sulfurtransferase activity
RG42_RS17010	COG2975	iron-sulfur cluster assembly
RG42_RS17015	COG0633	Ferredoxin
RG42_RS17035	COG0822	iron-sulfur transferase activity
RG42_RS17055	COG0483	inositol monophosphate 1-phosphatase activity
RG42_RS17060	COG1073	alpha beta
RG42_RS17065	COG3711	transcriptional antiterminator
RG42_RS17070	COG2814	Major facilitator Superfamily
RG42_RS17075	COG0583	DNA-binding transcription factor activity
RG42_RS17080	COG4638	Rieske (2fe-2S)
RG42_RS17105	COG2259	Doxx family
RG42_RS17110	COG2017	converts alpha-aldose to the beta-anomer
RG42_RS17115	COG1063	alcohol dehydrogenase
RG42_RS17120	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG42_RS17125	COG1129	ABC transporter
RG42_RS17130	COG1879	ABC-type sugar transport system periplasmic component
RG42_RS17135	COG0457	Tetratricopeptide repeat
RG42_RS17140	COG1940	carbohydrate kinase activity
RG42_RS17155	COG1017	nitric oxide dioxygenase activity
RG42_RS17155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG42_RS17160	COG0347	Belongs to the P(II) protein family
RG42_RS17165	COG2204	response regulator
RG42_RS17170	COG3170	Tfp pilus assembly protein FimV
RG42_RS17175	COG2205	protein histidine kinase activity
RG42_RS17180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RG42_RS17180	COG0047	phosphoribosylformylglycinamidine synthase activity
RG42_RS17200	COG0560	Phosphoserine phosphatase
RG42_RS17205	COG1737	Transcriptional regulator
RG42_RS17210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS17235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RG42_RS17260	COG0681	Belongs to the peptidase S26 family
RG42_RS17270	COG3086	response to oxidative stress
RG42_RS17275	COG3026	antisigma factor binding
RG42_RS17280	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
RG42_RS17285	COG1595	DNA-templated transcription, initiation
RG42_RS17295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RG42_RS17305	COG0513	Belongs to the DEAD box helicase family
RG42_RS17310	COG0583	DNA-binding transcription factor activity
RG42_RS17330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RG42_RS17335	COG3118	belongs to the thioredoxin family
RG42_RS17340	COG3148	PFAM DTW domain containing protein
RG42_RS17345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RG42_RS17345	COG1042	CoA-binding domain protein
RG42_RS17345	COG0045	succinate-CoA ligase (ADP-forming) activity
RG42_RS17350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RG42_RS17355	COG5544	Lipoprotein
RG42_RS17360	COG0477	Major facilitator Superfamily
RG42_RS17395	COG0542	response to heat
RG42_RS17400	COG1496	oxidoreductase activity
RG42_RS17405	COG0564	pseudouridine synthase activity
RG42_RS17410	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG42_RS17420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RG42_RS17425	COG0077	Prephenate dehydratase
RG42_RS17425	COG1605	Chorismate mutase
RG42_RS17430	COG0287	Prephenate dehydrogenase
RG42_RS17430	COG1605	Chorismate mutase
RG42_RS17435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RG42_RS17450	COG2199	diguanylate cyclase activity
RG42_RS17455	COG2885	chlorophyll binding
RG42_RS17480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RG42_RS17485	COG4137	Cytochrome C assembly protein
RG42_RS17490	COG4536	flavin adenine dinucleotide binding
RG42_RS17510	COG0497	DNA recombination
RG42_RS17515	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RG42_RS17525	COG2867	negative regulation of translational initiation
RG42_RS17540	COG3468	outer membrane autotransporter barrel domain protein
RG42_RS17575	COG0366	Alpha amylase catalytic
RG42_RS17585	COG0366	Alpha amylase catalytic
RG42_RS17590	COG0366	Alpha amylase catalytic
RG42_RS17600	COG0579	oxidoreductase
RG42_RS17605	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS17610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RG42_RS17615	COG1113	amino acid transport
RG42_RS17620	COG1802	Transcriptional regulator
RG42_RS17625	COG1652	LysM domain
RG42_RS17630	COG0401	homolog of Blt101
RG42_RS17635	COG0640	Transcriptional regulator
RG42_RS17640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RG42_RS17645	COG2916	Histone family protein nucleoid-structuring protein H-NS
RG42_RS17660	COG4575	ribosome binding
RG42_RS17665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RG42_RS17675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG42_RS17680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RG42_RS17690	COG4175	Glycine betaine
RG42_RS17695	COG4176	ABC-type proline glycine betaine transport system permease component
RG42_RS17700	COG2113	Glycine betaine
RG42_RS17705	COG2814	Major facilitator Superfamily
RG42_RS17710	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RG42_RS17720	COG1846	Transcriptional regulator
RG42_RS17725	COG1566	PFAM secretion protein HlyD family protein
RG42_RS17730	COG2814	Major facilitator Superfamily
RG42_RS17745	COG1238	metal cluster binding
RG42_RS17750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG42_RS17780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RG42_RS17805	COG1546	Belongs to the CinA family
RG42_RS17810	COG2951	lytic endotransglycosylase activity
RG42_RS17815	COG3730	PTS system glucitol sorbitol-specific
RG42_RS17820	COG3732	PTS system glucitol sorbitol-specific
RG42_RS17825	COG3731	PTS system glucitol sorbitol-specific IIA component
RG42_RS17830	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS17835	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS17840	COG1349	DNA-binding transcription factor activity
RG42_RS17845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RG42_RS17845	COG0517	IMP dehydrogenase activity
RG42_RS17870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RG42_RS17875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS17880	COG1609	Transcriptional regulator
RG42_RS17885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS17885	COG1263	PTS System
RG42_RS17890	COG2723	6-phospho-beta-galactosidase activity
RG42_RS17895	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RG42_RS17905	COG3260	NADH ubiquinone oxidoreductase 20
RG42_RS17910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RG42_RS17915	COG3261	NADH dehydrogenase
RG42_RS17915	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
RG42_RS17920	COG0650	Formate hydrogenlyase subunit 4
RG42_RS17925	COG0651	ATP synthesis coupled electron transport
RG42_RS17930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS17945	COG0375	protein maturation
RG42_RS17950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RG42_RS17955	COG0298	carbon dioxide binding
RG42_RS17960	COG0409	Hydrogenase expression formation protein
RG42_RS17965	COG0309	Hydrogenase expression formation protein (HypE)
RG42_RS17970	COG3604	Transcriptional regulator
RG42_RS17985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RG42_RS17990	COG1349	DNA-binding transcription factor activity
RG42_RS17995	COG2084	Dehydrogenase
RG42_RS18000	COG3395	kinase activity
RG42_RS18005	COG0235	Class ii aldolase
RG42_RS18010	COG3622	Belongs to the hyi family
RG42_RS18015	COG2610	gluconate transmembrane transporter activity
RG42_RS18020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RG42_RS18025	COG1388	LysM domain
RG42_RS18025	COG4942	peptidase
RG42_RS18080	COG2234	aminopeptidase activity
RG42_RS18085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RG42_RS18090	COG1518	maintenance of DNA repeat elements
RG42_RS18105	COG1857	crispr-associated protein
RG42_RS18130	COG1203	CRISPR-associated helicase, Cas3
RG42_RS18150	COG0720	synthase
RG42_RS18160	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
RG42_RS18165	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RG42_RS18170	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RG42_RS18180	COG0477	Major facilitator Superfamily
RG42_RS18185	COG0277	FAD linked oxidase domain protein
RG42_RS18190	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS18195	COG2223	nitrite transmembrane transporter activity
RG42_RS18200	COG1070	Carbohydrate kinase
RG42_RS18205	COG0602	queuosine metabolic process
RG42_RS18215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RG42_RS18230	COG3956	TIGRFAM MazG family protein
RG42_RS18235	COG2337	Toxic component of a toxin-antitoxin (TA) module
RG42_RS18240	COG2336	PFAM SpoVT AbrB
RG42_RS18245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RG42_RS18250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RG42_RS18255	COG2205	protein histidine kinase activity
RG42_RS18255	COG3437	response regulator, receiver
RG42_RS18255	COG3850	Histidine kinase
RG42_RS18255	COG4999	Histidine kinase
RG42_RS18260	COG4948	Mandelate Racemase Muconate Lactonizing
RG42_RS18265	COG4948	Mandelate Racemase Muconate Lactonizing
RG42_RS18270	COG2271	Major facilitator Superfamily
RG42_RS18275	COG0716	FMN binding
RG42_RS18280	COG0564	pseudouridine synthase activity
RG42_RS18285	COG3098	single-species biofilm formation
RG42_RS18305	COG1611	Belongs to the LOG family
RG42_RS18310	COG0814	amino acid
RG42_RS18315	COG1760	l-serine dehydratase
RG42_RS18325	COG1454	alcohol dehydrogenase
RG42_RS18330	COG0235	Class ii aldolase
RG42_RS18335	COG0738	Major facilitator superfamily
RG42_RS18345	COG1070	Carbohydrate kinase
RG42_RS18355	COG1349	DNA-binding transcription factor activity
RG42_RS18365	COG2363	Small membrane protein
RG42_RS18370	COG0583	DNA-binding transcription factor activity
RG42_RS18380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RG42_RS18385	COG2166	iron-sulfur cluster assembly
RG42_RS18390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RG42_RS18395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RG42_RS18420	COG0860	N-Acetylmuramoyl-L-alanine amidase
RG42_RS18425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RG42_RS18425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RG42_RS18430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RG42_RS18435	COG1074	ATP-dependent DNA helicase activity
RG42_RS18440	COG1025	Belongs to the peptidase M16 family
RG42_RS18445	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
RG42_RS18450	COG4967	type IV pilus modification protein PilV
RG42_RS18460	COG4795	General secretion pathway protein
RG42_RS18465	COG2165	general secretion pathway protein
RG42_RS18480	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
RG42_RS18505	COG0861	Integral membrane protein TerC family
RG42_RS18515	COG0667	Aldo Keto reductase
RG42_RS18535	COG1609	Transcriptional regulator
RG42_RS18545	COG0583	DNA-binding transcription factor activity
RG42_RS18550	COG1794	racemase activity, acting on amino acids and derivatives
RG42_RS18555	COG2814	Major facilitator Superfamily
RG42_RS18560	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS18570	COG0183	Belongs to the thiolase family
RG42_RS18575	COG0814	amino acid
RG42_RS18580	COG2771	luxR family
RG42_RS18585	COG3710	Transcriptional regulator
RG42_RS18610	COG0457	Tetratricopeptide repeat
RG42_RS18620	COG3710	Transcriptional regulator
RG42_RS18620	COG0457	Tetratricopeptide repeat
RG42_RS18635	COG2197	response regulator
RG42_RS18640	COG2197	response regulator
RG42_RS18725	COG3387	PFAM Glycoside hydrolase 15-related
RG42_RS18730	COG3385	transposase activity
RG42_RS18755	COG3387	PFAM Glycoside hydrolase 15-related
RG42_RS18765	COG4942	peptidase
RG42_RS18775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RG42_RS18780	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RG42_RS18785	COG2080	2 iron, 2 sulfur cluster binding
RG42_RS18790	COG3829	transcription factor binding
RG42_RS18795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RG42_RS18800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RG42_RS18805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RG42_RS18815	COG0549	Belongs to the carbamate kinase family
RG42_RS18825	COG3608	succinylglutamate desuccinylase aspartoacylase
RG42_RS18825	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RG42_RS18830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RG42_RS18835	COG2068	MobA-Related Protein
RG42_RS18840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS18840	COG0493	'glutamate synthase
RG42_RS18845	COG0402	S-adenosylhomocysteine deaminase activity
RG42_RS18850	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RG42_RS18855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RG42_RS18855	COG2080	2 iron, 2 sulfur cluster binding
RG42_RS18860	COG2233	PERMEase
RG42_RS18865	COG0402	S-adenosylhomocysteine deaminase activity
RG42_RS18870	COG2252	PERMEase
RG42_RS18875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS18880	COG0493	'glutamate synthase
RG42_RS18880	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS18890	COG2233	PERMEase
RG42_RS18905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RG42_RS18915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RG42_RS18920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RG42_RS18925	COG4974	Belongs to the 'phage' integrase family
RG42_RS18930	COG0716	FMN binding
RG42_RS18940	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RG42_RS18950	COG1272	protein, Hemolysin III
RG42_RS18960	COG2723	6-phospho-beta-galactosidase activity
RG42_RS18965	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS18985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RG42_RS18990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RG42_RS18995	COG0006	proline dipeptidase activity
RG42_RS19020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RG42_RS19030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RG42_RS19055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RG42_RS19055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RG42_RS19060	COG1703	isobutyryl-CoA mutase activity
RG42_RS19065	COG1024	Enoyl-CoA hydratase
RG42_RS19070	COG0427	acetyl-CoA hydrolase
RG42_RS19080	COG2968	Membrane
RG42_RS19085	COG1279	arginine transmembrane transporter activity
RG42_RS19090	COG0668	transmembrane transport
RG42_RS19095	COG0191	fructose-bisphosphate aldolase activity
RG42_RS19115	COG1072	(Pantothenic acid kinase))
RG42_RS19120	COG3722	fumarate hydratase activity
RG42_RS19130	COG1063	alcohol dehydrogenase
RG42_RS19135	COG2213	PTS system mannitol-specific
RG42_RS19140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS19145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RG42_RS19150	COG0501	Belongs to the peptidase M48B family
RG42_RS19160	COG1166	arginine decarboxylase activity
RG42_RS19190	COG2814	Major facilitator Superfamily
RG42_RS19200	COG2356	endonuclease I
RG42_RS19205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RG42_RS19210	COG0189	ligase activity
RG42_RS19225	COG2805	Type II/IV secretion system protein
RG42_RS19230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RG42_RS19235	COG0762	integral membrane protein
RG42_RS19245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RG42_RS19250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RG42_RS19260	COG0252	asparaginase activity
RG42_RS19270	COG3171	Protein conserved in bacteria
RG42_RS19285	COG1194	a g-specific adenine glycosylase
RG42_RS19300	COG2211	Major facilitator Superfamily
RG42_RS19305	COG1982	Orn Lys Arg decarboxylase major
RG42_RS19315	COG1811	Na channel or pump
RG42_RS19325	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
RG42_RS19355	COG2165	general secretion pathway protein
RG42_RS19360	COG1459	type II secretion system
RG42_RS19365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RG42_RS19375	COG3031	protein transport across the cell outer membrane
RG42_RS19385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RG42_RS19395	COG3064	Membrane
RG42_RS19410	COG1620	l-lactate permease
RG42_RS19415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RG42_RS19420	COG3193	protein, possibly involved in utilization of glycolate and propanediol
RG42_RS19425	COG0247	lactate metabolic process
RG42_RS19430	COG0277	FAD linked oxidase domain protein
RG42_RS19435	COG0277	FAD linked oxidase domain protein
RG42_RS19440	COG2186	Transcriptional regulator
RG42_RS19445	COG0456	acetyltransferase
RG42_RS19450	COG0318	PFAM AMP-dependent synthetase and ligase
RG42_RS19460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RG42_RS19465	COG0156	8-amino-7-oxononanoate synthase activity
RG42_RS19475	COG0795	lipopolysaccharide-transporting ATPase activity
RG42_RS19480	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
RG42_RS19495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RG42_RS19500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RG42_RS19505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RG42_RS19510	COG0306	phosphate transporter
RG42_RS19515	COG0754	glutathionylspermidine amidase activity
RG42_RS19520	COG0625	glutathione transferase activity
RG42_RS19525	COG0298	carbon dioxide binding
RG42_RS19535	COG1773	rubredoxin
RG42_RS19540	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RG42_RS19545	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RG42_RS19550	COG5557	Pfam Polysulphide reductase, NrfD
RG42_RS19555	COG0437	4 iron, 4 sulfur cluster binding
RG42_RS19560	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RG42_RS19585	COG0667	Aldo Keto reductase
RG42_RS19595	COG1028	Short-chain dehydrogenase reductase Sdr
RG42_RS19605	COG0848	biopolymer transport protein
RG42_RS19610	COG0811	peptide transport
RG42_RS19620	COG0626	cystathionine gamma-synthase activity
RG42_RS19625	COG0586	Pfam SNARE associated Golgi protein
RG42_RS19630	COG2207	Transcriptional regulator
RG42_RS19640	COG1979	alcohol dehydrogenase
RG42_RS19645	COG0656	L-ascorbic acid biosynthetic process
RG42_RS19655	COG4238	major outer membrane lipoprotein
RG42_RS19660	COG1032	radical SAM domain protein
RG42_RS19665	COG2132	Multicopper oxidase
RG42_RS19670	COG0204	Acyl-transferase
RG42_RS19680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RG42_RS19685	COG4166	transmembrane transport
RG42_RS19690	COG2944	sequence-specific DNA binding
RG42_RS19700	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RG42_RS19705	COG3111	PFAM Bacterial OB fold (BOF) protein
RG42_RS19710	COG0745	RESPONSE REGULATOR receiver
RG42_RS19715	COG0642	Histidine kinase
RG42_RS19725	COG2249	NAD(P)H dehydrogenase (quinone) activity
RG42_RS19730	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RG42_RS19735	COG0187	DNA topoisomerase II activity
RG42_RS19740	COG3150	esterase
RG42_RS19745	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RG42_RS19750	COG3151	Protein conserved in bacteria
RG42_RS19755	COG0494	nUDIX hydrolase
RG42_RS19760	COG1538	Outer membrane efflux protein
RG42_RS19775	COG0754	glutathionylspermidine amidase activity
RG42_RS19780	COG3384	dioxygenase
RG42_RS19800	COG2960	long-chain fatty acid transporting porin activity
RG42_RS19805	COG3539	Fimbrial protein
RG42_RS19810	COG3188	usher protein
RG42_RS19815	COG3121	Chaperone
RG42_RS19820	COG3539	Fimbrial protein
RG42_RS19830	COG1585	Membrane protein implicated in regulation of membrane protease activity
RG42_RS19835	COG2268	Band 7 protein
RG42_RS19860	COG3025	triphosphatase activity
RG42_RS19870	COG4991	sh3 domain protein
RG42_RS19885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RG42_RS19895	COG0583	DNA-binding transcription factor activity
RG42_RS19905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RG42_RS19910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RG42_RS19915	COG0471	metal ion transport
RG42_RS19930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RG42_RS19935	COG0358	DNA primase activity
RG42_RS19945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RG42_RS19960	COG2375	cellular response to nickel ion
RG42_RS19970	COG1695	Transcriptional regulator
RG42_RS19975	COG0840	transmembrane signaling receptor activity
RG42_RS19990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RG42_RS20000	COG1609	Transcriptional regulator
RG42_RS20005	COG3250	beta-galactosidase activity
RG42_RS20010	COG2731	YhcH YjgK YiaL family protein
RG42_RS20015	COG0531	amino acid
RG42_RS20025	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
RG42_RS20025	COG3408	Glycogen debranching enzyme
RG42_RS20030	COG1902	pentaerythritol trinitrate reductase activity
RG42_RS20030	COG0446	pyridine nucleotide-disulphide oxidoreductase
RG42_RS20035	COG5499	transcription regulator containing HTH domain
RG42_RS20040	COG4680	protein conserved in bacteria
RG42_RS20055	COG1451	nucleotide metabolic process
RG42_RS20060	COG2949	membrane
RG42_RS20065	COG0673	inositol 2-dehydrogenase activity
RG42_RS20070	COG0861	Integral membrane protein TerC family
RG42_RS20075	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
RG42_RS20085	COG2721	sulfolactate sulfo-lyase activity
RG42_RS20095	COG2271	Major facilitator Superfamily
RG42_RS20100	COG2186	Transcriptional regulator
RG42_RS20105	COG0586	Pfam SNARE associated Golgi protein
RG42_RS20115	COG1422	Protein of unknown function (DUF1090)
RG42_RS20120	COG4575	ribosome binding
RG42_RS20125	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
RG42_RS20135	COG2259	Doxx family
RG42_RS20140	COG0435	Glutathione S-transferase
RG42_RS20145	COG3152	Membrane
RG42_RS20150	COG3152	Membrane
RG42_RS20160	COG0583	DNA-binding transcription factor activity
RG42_RS20165	COG1741	Belongs to the pirin family
RG42_RS20180	COG0814	amino acid
RG42_RS20185	COG1760	l-serine dehydratase
RG42_RS20190	COG0251	oxidation-reduction process
RG42_RS20195	COG1882	Formate acetyltransferase
RG42_RS20200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RG42_RS20210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RG42_RS20215	COG0583	DNA-binding transcription factor activity
RG42_RS20240	COG1929	Belongs to the glycerate kinase type-1 family
RG42_RS20245	COG2084	Dehydrogenase
RG42_RS20255	COG2271	Major facilitator Superfamily
RG42_RS20260	COG2721	sulfolactate sulfo-lyase activity
RG42_RS20265	COG2002	toxin-antitoxin pair type II binding
RG42_RS20275	COG1349	DNA-binding transcription factor activity
RG42_RS20290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS20300	COG3716	PTS system mannose fructose sorbose family IID component
RG42_RS20305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS20310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RG42_RS20315	COG2222	sugar isomerase
RG42_RS20325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS20330	COG3715	PTS system
RG42_RS20335	COG3716	PTS system mannose fructose sorbose family IID component
RG42_RS20340	COG0363	glucosamine-6-phosphate deaminase activity
RG42_RS20345	COG3539	Fimbrial protein
RG42_RS20350	COG3121	Chaperone
RG42_RS20360	COG3539	Fimbrial protein
RG42_RS20365	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RG42_RS20370	COG3107	peptidoglycan biosynthetic process
RG42_RS20385	COG2823	Periplasmic or secreted lipoprotein
RG42_RS20390	COG0701	Predicted permease
RG42_RS20395	COG0702	epimerase
RG42_RS20400	COG0693	protein deglycase activity
RG42_RS20415	COG3153	acetyltransferase
RG42_RS20420	COG3154	lipid carrier protein
RG42_RS20425	COG0826	peptidase U32
RG42_RS20430	COG0826	peptidase U32
RG42_RS20435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RG42_RS20440	COG0814	amino acid
RG42_RS20450	COG0513	Belongs to the DEAD box helicase family
RG42_RS20490	COG0195	Participates in both transcription termination and antitermination
RG42_RS20510	COG2194	sulfuric ester hydrolase activity
RG42_RS20525	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RG42_RS20535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RG42_RS20540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RG42_RS20550	COG1534	Rna-binding protein
RG42_RS20555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RG42_RS20560	COG2027	D-alanyl-D-alanine carboxypeptidase
RG42_RS20570	COG0697	spore germination
RG42_RS20585	COG0142	geranyltranstransferase activity
RG42_RS20590	COG3423	Transcriptional regulator
RG42_RS20600	COG5007	Belongs to the BolA IbaG family
RG42_RS20605	COG3113	response to antibiotic
RG42_RS20610	COG2854	intermembrane phospholipid transfer
RG42_RS20615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RG42_RS20620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RG42_RS20625	COG1127	ABC transporter
RG42_RS20630	COG0530	calcium, potassium:sodium antiporter activity
RG42_RS20635	COG0517	IMP dehydrogenase activity
RG42_RS20635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RG42_RS20640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RG42_RS20645	COG3117	lipopolysaccharide transmembrane transporter activity
RG42_RS20650	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RG42_RS20655	COG1137	ATPase activity
RG42_RS20660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RG42_RS20665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RG42_RS20680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS20685	COG0515	serine threonine protein kinase
RG42_RS20695	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
RG42_RS20700	COG5002	protein histidine kinase activity
RG42_RS20700	COG0784	Response regulator, receiver
RG42_RS20700	COG2198	Histidine kinase
RG42_RS20705	COG1242	4 iron, 4 sulfur cluster binding
RG42_RS20720	COG0069	glutamate synthase activity
RG42_RS20720	COG0067	glutamate synthase
RG42_RS20720	COG0070	glutamate synthase
RG42_RS20725	COG0493	'glutamate synthase
RG42_RS20740	COG3539	Fimbrial protein
RG42_RS20745	COG3121	Chaperone
RG42_RS20750	COG3188	usher protein
RG42_RS20760	COG3539	Fimbrial protein
RG42_RS20765	COG4804	nuclease activity
RG42_RS20770	COG2731	YhcH YjgK YiaL family protein
RG42_RS20805	COG3069	C4-dicarboxylate transmembrane transporter activity
RG42_RS20810	COG2969	positive regulation of protein catabolic process
RG42_RS20815	COG0625	glutathione transferase activity
RG42_RS20830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RG42_RS20835	COG3105	Protein conserved in bacteria
RG42_RS20840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RG42_RS20845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RG42_RS20865	COG2732	(Barnase) inhibitor
RG42_RS20885	COG0583	DNA-binding transcription factor activity
RG42_RS20890	COG0312	modulator of DNA gyrase
RG42_RS20900	COG3164	Protein of unknown function
RG42_RS20905	COG1530	ribonuclease E activity
RG42_RS20910	COG0424	maF-like protein
RG42_RS20915	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RG42_RS20920	COG1792	Involved in formation and maintenance of cell shape
RG42_RS20925	COG1077	Cell shape determining protein MreB Mrl
RG42_RS20940	COG2199	diguanylate cyclase activity
RG42_RS20940	COG2200	EAL domain
RG42_RS20945	COG0604	alcohol dehydrogenase
RG42_RS20960	COG0511	ligase activity, forming carbon-carbon bonds
RG42_RS20965	COG0439	Biotin carboxylase
RG42_RS20970	COG3924	membrane
RG42_RS20975	COG4145	pantothenate transmembrane transporter activity
RG42_RS20985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RG42_RS20995	COG2189	Belongs to the N(4) N(6)-methyltransferase family
RG42_RS21005	COG1309	transcriptional regulator
RG42_RS21015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG42_RS21020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG42_RS21025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG42_RS21040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RG42_RS21045	COG4597	amino acid ABC transporter
RG42_RS21050	COG0765	amino acid transport
RG42_RS21055	COG1126	abc transporter atp-binding protein
RG42_RS21095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RG42_RS21115	COG0551	DNA topoisomerase type I activity
RG42_RS21125	COG0758	DNA mediated transformation
RG42_RS21145	COG0569	domain protein
RG42_RS21155	COG3036	rescue of stalled ribosome
RG42_RS21160	COG0789	Transcriptional regulator
RG42_RS21200	COG0201	protein transport
RG42_RS21290	COG0089	rRNA binding
RG42_RS21315	COG3267	Type II secretory pathway component ExeA
RG42_RS21315	COG3409	Peptidoglycan-binding domain 1 protein
RG42_RS21320	COG3031	protein transport across the cell outer membrane
RG42_RS21325	COG1450	Type ii and iii secretion system protein
RG42_RS21330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RG42_RS21335	COG1459	type II secretion system
RG42_RS21340	COG2165	general secretion pathway protein
RG42_RS21345	COG2165	general secretion pathway protein
RG42_RS21350	COG2165	general secretion pathway protein
RG42_RS21355	COG4795	General secretion pathway protein
RG42_RS21360	COG3156	type II secretion system protein K
RG42_RS21365	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
RG42_RS21385	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
RG42_RS21390	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
RG42_RS21395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RG42_RS21400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RG42_RS21405	COG2193	ferroxidase activity
RG42_RS21410	COG2906	2 iron, 2 sulfur cluster binding
RG42_RS21415	COG3979	chitinase
RG42_RS21455	COG2964	Protein conserved in bacteria
RG42_RS21460	COG0545	Peptidyl-prolyl cis-trans isomerase
RG42_RS21470	COG1047	Peptidyl-prolyl cis-trans
RG42_RS21475	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
RG42_RS21495	COG0488	(ABC) transporter
RG42_RS21500	COG0429	hydrolase of the alpha beta-hydrolase fold
RG42_RS21510	COG3954	Phosphoribulokinase
RG42_RS21515	COG1765	OsmC-like protein
RG42_RS21525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RG42_RS21530	COG1289	transmembrane transporter activity
RG42_RS21535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RG42_RS21540	COG0512	Glutamine amidotransferase of anthranilate synthase
RG42_RS21545	COG2184	nucleotidyltransferase activity
RG42_RS21555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RG42_RS21565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RG42_RS21570	COG2146	nitrite reductase [NAD(P)H] activity
RG42_RS21575	COG2116	formate transmembrane transporter activity
RG42_RS21590	COG0531	amino acid
RG42_RS21595	COG2222	sugar isomerase
RG42_RS21600	COG1082	Xylose isomerase domain protein TIM barrel
RG42_RS21605	COG1082	Xylose isomerase domain protein TIM barrel
RG42_RS21610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS21615	COG2188	Transcriptional regulator
RG42_RS21620	COG0626	cystathionine gamma-synthase activity
RG42_RS21635	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RG42_RS21640	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RG42_RS21645	COG3457	Alanine racemase
RG42_RS21655	COG2188	Transcriptional regulator
RG42_RS21665	COG0180	Tryptophanyl-tRNA synthetase
RG42_RS21670	COG0546	phosphoglycolate phosphatase activity
RG42_RS21675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RG42_RS21680	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RG42_RS21685	COG3266	domain, Protein
RG42_RS21700	COG4796	Type ii and iii secretion system protein
RG42_RS21715	COG3166	PFAM Fimbrial assembly family protein
RG42_RS21720	COG4972	Pilus assembly protein
RG42_RS21725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RG42_RS21730	COG0494	nUDIX hydrolase
RG42_RS21740	COG1011	Hydrolase
RG42_RS21745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RG42_RS21755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RG42_RS21785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RG42_RS21790	COG2183	response to ionizing radiation
RG42_RS21800	COG1918	ferrous iron import across plasma membrane
RG42_RS21805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RG42_RS21820	COG5464	transposase or invertase
RG42_RS21830	COG1040	competence protein
RG42_RS21840	COG2610	gluconate transmembrane transporter activity
RG42_RS21845	COG1640	4-alpha-glucanotransferase
RG42_RS21850	COG0058	SHG alpha-glucan phosphorylase activity
RG42_RS21865	COG1690	Belongs to the RtcB family
RG42_RS21870	COG4650	regulator
RG42_RS21875	COG1349	DNA-binding transcription factor activity
RG42_RS21890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RG42_RS21895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RG42_RS21900	COG0058	SHG alpha-glucan phosphorylase activity
RG42_RS21925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RG42_RS21930	COG2095	MarC family integral membrane protein
RG42_RS21935	COG2610	gluconate transmembrane transporter activity
RG42_RS21940	COG3265	gluconokinase activity
RG42_RS21945	COG1609	Transcriptional regulator
RG42_RS21950	COG1741	Belongs to the pirin family
RG42_RS21955	COG0673	inositol 2-dehydrogenase activity
RG42_RS21960	COG1247	-acetyltransferase
RG42_RS21965	COG3157	Type VI secretion system effector, Hcp
RG42_RS21985	COG0405	Gamma-glutamyltransferase
RG42_RS21995	COG0584	glycerophosphoryl diester phosphodiesterase
RG42_RS22000	COG3842	ATPase activity
RG42_RS22005	COG0395	ABC-type sugar transport system, permease component
RG42_RS22010	COG1175	transmembrane transport
RG42_RS22015	COG1653	transport
RG42_RS22020	COG0410	ABC transporter
RG42_RS22025	COG0411	ABC transporter
RG42_RS22030	COG4177	L-phenylalanine transmembrane transporter activity
RG42_RS22035	COG0559	Belongs to the binding-protein-dependent transport system permease family
RG42_RS22040	COG0683	leucine binding
RG42_RS22050	COG0456	acetyltransferase
RG42_RS22055	COG0683	leucine binding
RG42_RS22060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RG42_RS22065	COG2177	Part of the ABC transporter FtsEX involved in
RG42_RS22070	COG2884	Cell division ATP-binding protein ftsE
RG42_RS22075	COG0552	protein localization to endoplasmic reticulum
RG42_RS22080	COG0742	ribosomal rna small subunit methyltransferase
RG42_RS22085	COG3776	membrane
RG42_RS22095	COG3714	YhhN family
RG42_RS22100	COG2217	Heavy metal translocating P-type atpase
RG42_RS22110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RG42_RS22120	COG0477	Major facilitator Superfamily
RG42_RS22125	COG0628	permease
RG42_RS22130	COG2091	lysine biosynthetic process via aminoadipic acid
RG42_RS22135	COG0747	negative chemotaxis
RG42_RS22140	COG0601	transmembrane transport
RG42_RS22145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG42_RS22150	COG0444	Belongs to the ABC transporter superfamily
RG42_RS22155	COG1124	(ABC) transporter
RG42_RS22170	COG3209	COG3209 Rhs family protein
RG42_RS22180	COG1413	lyase activity
RG42_RS22185	COG5433	transposase activity
RG42_RS22190	COG0842	Transport permease protein
RG42_RS22195	COG0842	Transport permease protein
RG42_RS22195	COG1129	ABC transporter
RG42_RS22200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG42_RS22235	COG2081	HI0933 family
RG42_RS22240	COG0306	phosphate transporter
RG42_RS22255	COG0589	response to stress
RG42_RS22265	COG3104	oligopeptide transport
RG42_RS22275	COG0339	signal peptide processing
RG42_RS22280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RG42_RS22285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RG42_RS22300	COG0640	Transcriptional regulator
RG42_RS22305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RG42_RS22310	COG1393	Belongs to the ArsC family
RG42_RS22320	COG3065	identical protein binding
RG42_RS22330	COG2197	response regulator
RG42_RS22335	COG1285	pathogenesis
RG42_RS22350	COG3247	response to pH
RG42_RS22355	COG2771	luxR family
RG42_RS22365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RG42_RS22370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RG42_RS22380	COG2207	Transcriptional regulator
RG42_RS22385	COG2207	Transcriptional regulator
RG42_RS22390	COG0076	glutamate decarboxylase activity
RG42_RS22395	COG1858	cytochrome C peroxidase
RG42_RS22405	COG2197	response regulator
RG42_RS22410	COG0583	DNA-binding transcription factor activity
RG42_RS22415	COG1295	ribonuclease BN
RG42_RS22420	COG0477	Major facilitator Superfamily
RG42_RS22425	COG2982	Protein involved in outer membrane biogenesis
RG42_RS22430	COG2200	EAL domain
RG42_RS22440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS22445	COG0612	Peptidase, M16
RG42_RS22465	COG2199	diguanylate cyclase activity
RG42_RS22465	COG2200	EAL domain
RG42_RS22470	COG0457	Tetratricopeptide repeat
RG42_RS22470	COG3118	belongs to the thioredoxin family
RG42_RS22475	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RG42_RS22480	COG1215	transferase activity, transferring glycosyl groups
RG42_RS22485	COG1215	transferase activity, transferring glycosyl groups
RG42_RS22530	COG0814	amino acid
RG42_RS22535	COG4608	Belongs to the ABC transporter superfamily
RG42_RS22540	COG0444	Belongs to the ABC transporter superfamily
RG42_RS22545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RG42_RS22550	COG0601	transmembrane transport
RG42_RS22560	COG0747	negative chemotaxis
RG42_RS22580	COG2194	sulfuric ester hydrolase activity
RG42_RS22585	COG2223	nitrite transmembrane transporter activity
RG42_RS22595	COG5571	outer membrane autotransporter
RG42_RS22600	COG2818	Glycosylase
RG42_RS22605	COG0456	acetyltransferase
RG42_RS22610	COG0243	molybdopterin cofactor binding
RG42_RS22615	COG2885	chlorophyll binding
RG42_RS22630	COG2944	sequence-specific DNA binding
RG42_RS22635	COG1278	Cold shock
RG42_RS22645	COG2963	transposase activity
RG42_RS22650	COG2801	Transposase and inactivated derivatives
RG42_RS22670	COG3274	enterobacterial common antigen metabolic process
RG42_RS22675	COG4682	membrane
RG42_RS22680	COG4682	membrane
RG42_RS22685	COG1070	Carbohydrate kinase
RG42_RS22695	COG4213	ABC transporter substrate-binding protein
RG42_RS22700	COG1129	ABC transporter
RG42_RS22705	COG4214	carbohydrate transport
RG42_RS22710	COG2207	Transcriptional regulator
RG42_RS22710	COG1609	Transcriptional regulator
RG42_RS22715	COG2992	FlgJ-related protein
RG42_RS22720	COG0366	Alpha amylase catalytic
RG42_RS22725	COG3977	Valine--pyruvate aminotransferase
RG42_RS22730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RG42_RS22735	COG1414	Transcriptional regulator
RG42_RS22745	COG2731	YhcH YjgK YiaL family protein
RG42_RS22750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RG42_RS22755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RG42_RS22760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RG42_RS22765	COG1070	Carbohydrate kinase
RG42_RS22770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RG42_RS22775	COG3623	hexulose-6-phosphate isomerase
RG42_RS22780	COG0235	Class ii aldolase
RG42_RS22785	COG3713	MltA-interacting MipA family protein
RG42_RS22790	COG0583	DNA-binding transcription factor activity
RG42_RS22795	COG1566	PFAM secretion protein HlyD family protein
RG42_RS22810	COG1012	belongs to the aldehyde dehydrogenase family
RG42_RS22815	COG1454	alcohol dehydrogenase
RG42_RS22820	COG3276	selenocysteine insertion sequence binding
RG42_RS22830	COG0625	glutathione transferase activity
RG42_RS22840	COG1413	lyase activity
RG42_RS22845	COG3209	COG3209 Rhs family protein
RG42_RS22850	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RG42_RS22875	COG1566	PFAM secretion protein HlyD family protein
RG42_RS22885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RG42_RS22885	COG2213	PTS system mannitol-specific
RG42_RS22895	COG3722	fumarate hydratase activity
RG42_RS22915	COG1620	l-lactate permease
RG42_RS22920	COG2186	Transcriptional regulator
RG42_RS22930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RG42_RS22935	COG1045	serine acetyltransferase
RG42_RS22950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RG42_RS22955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RG42_RS22970	COG4942	peptidase
RG42_RS22975	COG2861	carbohydrate metabolic process
RG42_RS22980	COG1216	Glycosyl transferase, family 2
RG42_RS22990	COG0156	8-amino-7-oxononanoate synthase activity
RG42_RS23000	COG0859	PFAM glycosyl transferase family 9
RG42_RS23005	COG0859	PFAM glycosyl transferase family 9
RG42_RS23025	COG3642	lipopolysaccharide core region biosynthetic process
RG42_RS23030	COG1442	glycosyl transferase family 8
RG42_RS23035	COG1442	glycosyl transferase family 8
RG42_RS23040	COG0438	transferase activity, transferring glycosyl groups
RG42_RS23045	COG1442	glycosyl transferase family 8
RG42_RS23050	COG0515	serine threonine protein kinase
RG42_RS23055	COG0438	transferase activity, transferring glycosyl groups
RG42_RS23060	COG0859	PFAM glycosyl transferase family 9
RG42_RS23065	COG1519	Transferase
RG42_RS23095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RG42_RS23125	COG1561	YicC-like family, N-terminal region
RG42_RS23130	COG3645	SOS response
RG42_RS23135	COG2860	membrane
RG42_RS23145	COG0194	GDP metabolic process
RG42_RS23155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RG42_RS23160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RG42_RS23165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RG42_RS23170	COG0786	glutamate:sodium symporter activity
RG42_RS23175	COG2233	PERMEase
RG42_RS23180	COG2982	Protein involved in outer membrane biogenesis
RG42_RS23185	COG1501	Belongs to the glycosyl hydrolase 31 family
RG42_RS23190	COG2211	Major facilitator Superfamily
RG42_RS23205	COG2814	Major facilitator Superfamily
RG42_RS23210	COG0697	spore germination
RG42_RS23215	COG1464	Belongs to the NlpA lipoprotein family
RG42_RS23250	COG2252	PERMEase
RG42_RS23260	COG2271	Major facilitator Superfamily
RG42_RS23265	COG2271	Major facilitator Superfamily
RG42_RS23270	COG3851	Histidine kinase
RG42_RS23275	COG2197	response regulator
RG42_RS23280	COG0440	acetolactate synthase activity
RG42_RS23285	COG0028	Belongs to the TPP enzyme family
RG42_RS23320	COG2814	Major facilitator Superfamily
RG42_RS23325	COG0641	radical SAM
RG42_RS23335	COG2149	membrane
RG42_RS23345	COG3119	arylsulfatase activity
RG42_RS23350	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RG42_RS23355	COG2207	Transcriptional regulator
RG42_RS23375	COG2188	Transcriptional regulator
RG42_RS23395	COG5645	(Lipo)protein
RG42_RS23400	COG0823	Involved in the tonB-independent uptake of proteins
RG42_RS23405	COG0644	oxidoreductase
RG42_RS23410	COG2271	Major facilitator Superfamily
RG42_RS23420	COG0800	Aldolase
RG42_RS23425	COG3734	2-keto-3-deoxy-galactonokinase
RG42_RS23430	COG2186	Transcriptional regulator
RG42_RS23440	COG0561	phosphatase activity
RG42_RS23445	COG3753	Protein conserved in bacteria
RG42_RS23450	COG0187	DNA topoisomerase II activity
RG42_RS23460	COG0592	DNA-directed DNA polymerase activity
RG42_RS23510	COG0814	amino acid
RG42_RS23525	COG2091	lysine biosynthetic process via aminoadipic acid
RG42_RS23530	COG0431	NADPH-dependent FMN reductase
RG42_RS23535	COG2252	PERMEase
RG42_RS23540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RG42_RS23550	COG3196	Protein conserved in bacteria
RG42_RS23555	COG4372	Transposase
RG42_RS23560	COG4372	Transposase
RG42_RS23565	COG3436	PFAM IS66 Orf2 family protein
RG42_RS23575	COG3196	Protein conserved in bacteria
RG42_RS23580	COG0363	glucosamine-6-phosphate deaminase activity
RG42_RS23585	COG2382	esterase
RG42_RS23595	COG2723	6-phospho-beta-galactosidase activity
RG42_RS23600	COG1263	PTS System
RG42_RS23600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RG42_RS23600	COG2190	(PTS) system
RG42_RS23605	COG3711	transcriptional antiterminator
RG42_RS23610	COG0704	Plays a role in the regulation of phosphate uptake
RG42_RS23615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RG42_RS23620	COG0581	inorganic phosphate transmembrane transporter activity
RG42_RS23625	COG0573	inorganic phosphate transmembrane transporter activity
RG42_RS23630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RG42_RS23635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RG42_RS23685	COG3312	ion transport
RG42_RS23700	COG0716	FMN binding
RG42_RS23705	COG1522	sequence-specific DNA binding
RG42_RS23735	COG1129	ABC transporter
RG42_RS23740	COG1172	Belongs to the binding-protein-dependent transport system permease family
RG42_RS23745	COG1879	ABC-type sugar transport system periplasmic component
RG42_RS23750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS23755	COG1609	Transcriptional regulator
RG42_RS23760	COG0477	Major facilitator Superfamily
RG42_RS23765	COG2186	Transcriptional regulator
RG42_RS23810	COG3085	chromosome segregation
RG42_RS23815	COG0606	chelatase, subunit chli
RG42_RS23830	COG3978	acetolactate synthase activity
RG42_RS23835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RG42_RS23845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RG42_RS23850	COG0583	DNA-binding transcription factor activity
RG42_RS23860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RG42_RS23865	COG3692	DNA binding
RG42_RS23870	COG3692	DNA binding
RG42_RS23875	COG0210	DNA helicase
RG42_RS23895	COG3118	belongs to the thioredoxin family
RG42_RS23905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RG42_RS23915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RG42_RS23920	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
RG42_RS23925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RG42_RS23930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RG42_RS23935	COG1088	dTDP-glucose 4,6-dehydratase activity
RG42_RS23940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RG42_RS23945	COG0456	acetyltransferase
RG42_RS23950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RG42_RS23955	COG2244	polysaccharide biosynthetic process
RG42_RS23975	COG1113	amino acid transport
RG42_RS24000	COG0641	radical SAM
RG42_RS24010	COG3119	arylsulfatase activity
RG42_RS24015	COG3071	HemY protein
RG42_RS24020	COG2959	enzyme of heme biosynthesis
RG42_RS24025	COG1587	Uroporphyrinogen-III synthase
RG42_RS24040	COG3072	Adenylate cyclase
RG42_RS24055	COG5567	small periplasmic lipoprotein
RG42_RS24065	COG3159	Protein conserved in bacteria
RG42_RS24075	COG1011	Hydrolase
RG42_RS24080	COG0210	DNA helicase
RG42_RS24085	COG3698	Phosphodiester glycosidase
RG42_RS24095	COG0598	Magnesium transport protein CorA
RG42_RS24110	COG2962	Rard protein
RG42_RS24115	COG2050	protein possibly involved in aromatic compounds catabolism
RG42_RS24120	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
RG42_RS24125	COG0514	ATP-dependent DNA helicase (RecQ)
RG42_RS24130	COG1280	lysine exporter protein (LysE YggA)
RG42_RS24135	COG1280	lysine exporter protein (LysE YggA)
RG42_RS24140	COG2267	carboxylic ester hydrolase activity
RG42_RS24145	COG0561	phosphatase activity
RG42_RS24150	COG0697	spore germination
RG42_RS24155	COG0583	DNA-binding transcription factor activity
RG42_RS24165	COG0412	Dienelactone hydrolase
RG42_RS24170	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
RG42_RS24180	COG1322	Protein conserved in bacteria
RG42_RS24190	COG3165	ubiquinone biosynthetic process from chorismate
RG42_RS24200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RG42_RS24205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RG42_RS24210	COG0805	protein transport
RG42_RS24215	COG0084	hydrolase, TatD family'
RG42_RS24220	COG0250	Participates in transcription elongation, termination and antitermination
RG42_RS24225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RG42_RS24230	COG0543	2 iron, 2 sulfur cluster binding
RG42_RS24240	COG0183	Belongs to the thiolase family
RG42_RS24255	COG1739	Uncharacterized protein family UPF0029
RG42_RS24260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RG42_RS24265	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
RG42_RS24405	COG2211	Major facilitator Superfamily
RG42_RS24420	COG1501	Belongs to the glycosyl hydrolase 31 family
RG42_RS24565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS24565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RG42_RS24760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RG42_RS24905	COG2194	sulfuric ester hydrolase activity
RG42_RS25090	COG2017	converts alpha-aldose to the beta-anomer
RG42_RS25385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RG42_RS25390	COG1494	fructose-1,6-bisphosphatase
RG42_RS25425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RG42_RS25440	COG5339	Protein conserved in bacteria
RG42_RS25465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RG42_RS25465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RG42_RS25570	COG1082	Xylose isomerase domain protein TIM barrel
RG42_RS25580	COG2271	Major facilitator Superfamily
RG42_RS25630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RG42_RS25690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response