locus-tag	class	description
ECDH1ME8569_RS00010	COG0527	aspartate kinase activity
ECDH1ME8569_RS00010	COG0460	homoserine dehydrogenase
ECDH1ME8569_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ECDH1ME8569_RS00040	COG1115	amino acid carrier protein
ECDH1ME8569_RS00045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECDH1ME8569_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECDH1ME8569_RS00055	COG1584	GPR1 FUN34 yaaH family protein
ECDH1ME8569_RS00060	COG4735	regulation of single-species biofilm formation
ECDH1ME8569_RS00080	COG3385	transposase activity
ECDH1ME8569_RS00090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ECDH1ME8569_RS00095	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS00120	COG0196	riboflavin kinase activity
ECDH1ME8569_RS00135	COG1047	Peptidyl-prolyl cis-trans
ECDH1ME8569_RS00165	COG0505	Belongs to the CarA family
ECDH1ME8569_RS00170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ECDH1ME8569_RS00225	COG0644	oxidoreductase
ECDH1ME8569_RS00230	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECDH1ME8569_RS00235	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS00250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ECDH1ME8569_RS00275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECDH1ME8569_RS00280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECDH1ME8569_RS00285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ECDH1ME8569_RS00295	COG0564	pseudouridine synthase activity
ECDH1ME8569_RS00305	COG0417	DNA replication proofreading
ECDH1ME8569_RS00310	COG0235	Class ii aldolase
ECDH1ME8569_RS00315	COG2160	L-arabinose isomerase activity
ECDH1ME8569_RS00320	COG1069	ribulokinase activity
ECDH1ME8569_RS00325	COG4977	sequence-specific DNA binding
ECDH1ME8569_RS00330	COG0586	Pfam SNARE associated Golgi protein
ECDH1ME8569_RS00335	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ECDH1ME8569_RS00340	COG1178	ABC-type Fe3 transport system permease component
ECDH1ME8569_RS00345	COG4143	(ABC) transporter
ECDH1ME8569_RS00360	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS00375	COG0473	3-isopropylmalate dehydrogenase activity
ECDH1ME8569_RS00390	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS00395	COG0028	Belongs to the TPP enzyme family
ECDH1ME8569_RS00400	COG0440	acetolactate synthase activity
ECDH1ME8569_RS00410	COG1609	Transcriptional regulator
ECDH1ME8569_RS00415	COG2001	Belongs to the MraZ family
ECDH1ME8569_RS00425	COG3116	cell division
ECDH1ME8569_RS00430	COG0768	penicillin binding
ECDH1ME8569_RS00435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECDH1ME8569_RS00440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ECDH1ME8569_RS00450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ECDH1ME8569_RS00455	COG0772	Belongs to the SEDS family
ECDH1ME8569_RS00470	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECDH1ME8569_RS00475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ECDH1ME8569_RS00480	COG0849	cell division
ECDH1ME8569_RS00485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ECDH1ME8569_RS00505	COG0494	nUDIX hydrolase
ECDH1ME8569_RS00525	COG0237	dephospho-CoA kinase activity
ECDH1ME8569_RS00535	COG1459	type II secretion system
ECDH1ME8569_RS00540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECDH1ME8569_RS00545	COG4969	Belongs to the N-Me-Phe pilin family
ECDH1ME8569_RS00555	COG0157	Belongs to the NadC ModD family
ECDH1ME8569_RS00560	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECDH1ME8569_RS00565	COG3725	Membrane protein required for beta-lactamase induction
ECDH1ME8569_RS00570	COG1113	amino acid transport
ECDH1ME8569_RS00575	COG2186	Transcriptional regulator
ECDH1ME8569_RS00580	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ECDH1ME8569_RS00585	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECDH1ME8569_RS00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECDH1ME8569_RS00595	COG3064	Membrane
ECDH1ME8569_RS00600	COG1049	propionate catabolic process, 2-methylcitrate cycle
ECDH1ME8569_RS00625	COG2132	Multicopper oxidase
ECDH1ME8569_RS00630	COG4993	Dehydrogenase
ECDH1ME8569_RS00635	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ECDH1ME8569_RS00640	COG0288	reversible hydration of carbon dioxide
ECDH1ME8569_RS00645	COG1131	(ABC) transporter
ECDH1ME8569_RS00650	COG0842	Transport permease protein
ECDH1ME8569_RS00655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS00660	COG0726	polysaccharide deacetylase
ECDH1ME8569_RS00670	COG5464	transposase or invertase
ECDH1ME8569_RS00685	COG3539	Fimbrial protein
ECDH1ME8569_RS00690	COG3539	Fimbrial protein
ECDH1ME8569_RS00695	COG3539	Fimbrial protein
ECDH1ME8569_RS00700	COG3539	Fimbrial protein
ECDH1ME8569_RS00705	COG3188	usher protein
ECDH1ME8569_RS00710	COG3121	Chaperone
ECDH1ME8569_RS00715	COG3539	Fimbrial protein
ECDH1ME8569_RS00720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ECDH1ME8569_RS00725	COG0617	tRNA 3'-terminal CCA addition
ECDH1ME8569_RS00735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECDH1ME8569_RS00745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ECDH1ME8569_RS00750	COG1643	Atp-dependent helicase
ECDH1ME8569_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ECDH1ME8569_RS00765	COG4774	siderophore transport
ECDH1ME8569_RS00770	COG1120	ATPase activity
ECDH1ME8569_RS00775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECDH1ME8569_RS00780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECDH1ME8569_RS00800	COG2860	membrane
ECDH1ME8569_RS00805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECDH1ME8569_RS00820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECDH1ME8569_RS00825	COG3835	regulator
ECDH1ME8569_RS00835	COG1408	metallophosphoesterase
ECDH1ME8569_RS00850	COG0024	Methionine aminopeptidase
ECDH1ME8569_RS00875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ECDH1ME8569_RS00880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ECDH1ME8569_RS00885	COG0575	Belongs to the CDS family
ECDH1ME8569_RS00890	COG0750	zinc metalloprotease
ECDH1ME8569_RS00900	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ECDH1ME8569_RS00905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECDH1ME8569_RS00930	COG0587	DNA-directed DNA polymerase activity
ECDH1ME8569_RS00940	COG1982	Orn Lys Arg decarboxylase major
ECDH1ME8569_RS00945	COG0346	lactoylglutathione lyase activity
ECDH1ME8569_RS00950	COG0037	tRNA processing
ECDH1ME8569_RS00955	COG4568	rho-dependent transcription termination
ECDH1ME8569_RS00965	COG4681	YaeQ
ECDH1ME8569_RS00970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECDH1ME8569_RS00975	COG3015	lipoprotein NlpE involved in copper resistance
ECDH1ME8569_RS00980	COG0791	NLP P60 protein
ECDH1ME8569_RS00990	COG1720	tRNA m6t6A37 methyltransferase activity
ECDH1ME8569_RS01000	COG1464	Belongs to the NlpA lipoprotein family
ECDH1ME8569_RS01005	COG2011	ABC-type metal ion transport system permease component
ECDH1ME8569_RS01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ECDH1ME8569_RS01015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECDH1ME8569_RS01050	COG0656	L-ascorbic acid biosynthetic process
ECDH1ME8569_RS01055	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS01065	COG2226	methyltransferase
ECDH1ME8569_RS01070	COG1388	LysM domain
ECDH1ME8569_RS01070	COG0741	lytic transglycosylase activity
ECDH1ME8569_RS01080	COG2226	methyltransferase
ECDH1ME8569_RS01090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECDH1ME8569_RS01110	COG4104	PAAR repeat-containing protein
ECDH1ME8569_RS01115	COG5433	transposase activity
ECDH1ME8569_RS01120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECDH1ME8569_RS01130	COG1960	acyl-CoA dehydrogenase activity
ECDH1ME8569_RS01140	COG0121	glutamine amidotransferase
ECDH1ME8569_RS01145	COG3034	peptidoglycan biosynthetic process
ECDH1ME8569_RS01150	COG3041	Addiction module toxin RelE StbE family
ECDH1ME8569_RS01155	COG3077	Addiction module antitoxin, RelB DinJ family
ECDH1ME8569_RS01160	COG0791	NLP P60 protein
ECDH1ME8569_RS01165	COG1943	Transposase
ECDH1ME8569_RS01185	COG2161	toxin-antitoxin pair type II binding
ECDH1ME8569_RS01195	COG0454	-acetyltransferase
ECDH1ME8569_RS01200	COG1690	Belongs to the RtcB family
ECDH1ME8569_RS01205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECDH1ME8569_RS01210	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECDH1ME8569_RS01230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECDH1ME8569_RS01260	COG2003	Belongs to the UPF0758 family
ECDH1ME8569_RS01280	COG2378	regulation of single-species biofilm formation
ECDH1ME8569_RS01295	COG3596	GTP binding
ECDH1ME8569_RS01300	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS01305	COG2963	transposase activity
ECDH1ME8569_RS01310	COG2826	transposase and inactivated derivatives, IS30 family
ECDH1ME8569_RS01315	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS01330	COG3344	reverse transcriptase
ECDH1ME8569_RS01340	COG0833	amino acid
ECDH1ME8569_RS01345	COG2040	homocysteine
ECDH1ME8569_RS01350	COG3842	ATPase activity
ECDH1ME8569_RS01355	COG1178	ABC-type Fe3 transport system permease component
ECDH1ME8569_RS01360	COG1662	PFAM IS1 transposase
ECDH1ME8569_RS01365	COG3677	Transposase
ECDH1ME8569_RS01365	COG1662	PFAM IS1 transposase
ECDH1ME8569_RS01370	COG2963	transposase activity
ECDH1ME8569_RS01380	COG3415	Transposase
ECDH1ME8569_RS01380	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS01385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECDH1ME8569_RS01390	COG0129	dihydroxy-acid dehydratase activity
ECDH1ME8569_RS01395	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS01400	COG3507	Belongs to the glycosyl hydrolase 43 family
ECDH1ME8569_RS01405	COG1414	Transcriptional regulator
ECDH1ME8569_RS01410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECDH1ME8569_RS01415	COG1662	PFAM IS1 transposase
ECDH1ME8569_RS01420	COG1061	Type III restriction enzyme res subunit
ECDH1ME8569_RS01430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECDH1ME8569_RS01450	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS01460	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS01465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ECDH1ME8569_RS01470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECDH1ME8569_RS01475	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECDH1ME8569_RS01480	COG2080	2 iron, 2 sulfur cluster binding
ECDH1ME8569_RS01485	COG3477	response to acidic pH
ECDH1ME8569_RS01490	COG0727	PFAM Uncharacterised protein family (UPF0153)
ECDH1ME8569_RS01495	COG3121	Chaperone
ECDH1ME8569_RS01505	COG3188	usher protein
ECDH1ME8569_RS01545	COG1388	LysM domain
ECDH1ME8569_RS01555	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS01560	COG2207	Transcriptional regulator
ECDH1ME8569_RS01560	COG3708	Transcriptional regulator
ECDH1ME8569_RS01565	COG3059	membrane
ECDH1ME8569_RS01575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECDH1ME8569_RS01580	COG2207	Transcriptional regulator
ECDH1ME8569_RS01585	COG0247	lactate metabolic process
ECDH1ME8569_RS01590	COG1139	Iron-sulfur cluster binding protein
ECDH1ME8569_RS01595	COG1556	Lactate utilization protein
ECDH1ME8569_RS01625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECDH1ME8569_RS01635	COG2200	EAL domain
ECDH1ME8569_RS01635	COG2771	luxR family
ECDH1ME8569_RS01640	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS01650	COG0666	response to abiotic stimulus
ECDH1ME8569_RS01660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECDH1ME8569_RS01665	COG1304	FMN binding
ECDH1ME8569_RS01675	COG0549	Belongs to the carbamate kinase family
ECDH1ME8569_RS01680	COG0402	S-adenosylhomocysteine deaminase activity
ECDH1ME8569_RS01685	COG1064	alcohol dehydrogenase
ECDH1ME8569_RS01700	COG1280	lysine exporter protein (LysE YggA)
ECDH1ME8569_RS01710	COG3829	transcription factor binding
ECDH1ME8569_RS01715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ECDH1ME8569_RS01720	COG0372	Belongs to the citrate synthase family
ECDH1ME8569_RS01725	COG2079	MmgE PrpD family protein
ECDH1ME8569_RS01730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECDH1ME8569_RS01735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ECDH1ME8569_RS01740	COG0402	S-adenosylhomocysteine deaminase activity
ECDH1ME8569_RS01745	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS01750	COG0288	reversible hydration of carbon dioxide
ECDH1ME8569_RS01760	COG2807	transmembrane transport
ECDH1ME8569_RS01765	COG0110	maltose O-acetyltransferase activity
ECDH1ME8569_RS01770	COG2223	nitrite transmembrane transporter activity
ECDH1ME8569_RS01775	COG3250	beta-galactosidase activity
ECDH1ME8569_RS01780	COG1609	Transcriptional regulator
ECDH1ME8569_RS01785	COG1414	Transcriptional regulator
ECDH1ME8569_RS01805	COG3971	2-oxopent-4-enoate hydratase activity
ECDH1ME8569_RS01820	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS01825	COG3122	Protein conserved in bacteria
ECDH1ME8569_RS01835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ECDH1ME8569_RS01870	COG1215	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS01875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ECDH1ME8569_RS01880	COG4521	taurine ABC transporter
ECDH1ME8569_RS01890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECDH1ME8569_RS01895	COG2175	clavaminate synthase activity
ECDH1ME8569_RS01900	COG0113	porphobilinogen synthase activity
ECDH1ME8569_RS01915	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS01925	COG3468	outer membrane autotransporter barrel domain protein
ECDH1ME8569_RS01930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECDH1ME8569_RS01935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECDH1ME8569_RS01945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ECDH1ME8569_RS01965	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECDH1ME8569_RS01980	COG1785	Belongs to the alkaline phosphatase family
ECDH1ME8569_RS01990	COG3706	GGDEF domain
ECDH1ME8569_RS01995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ECDH1ME8569_RS02020	COG4126	flavin adenine dinucleotide binding
ECDH1ME8569_RS02040	COG1940	carbohydrate kinase activity
ECDH1ME8569_RS02045	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS02050	COG0419	ATPase involved in DNA repair
ECDH1ME8569_RS02055	COG0420	3'-5' exonuclease activity
ECDH1ME8569_RS02060	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS02065	COG5002	protein histidine kinase activity
ECDH1ME8569_RS02070	COG1114	Component of the transport system for branched-chain amino acids
ECDH1ME8569_RS02075	COG1113	amino acid transport
ECDH1ME8569_RS02080	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS02100	COG1862	Preprotein translocase
ECDH1ME8569_RS02105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECDH1ME8569_RS02110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECDH1ME8569_RS02115	COG1403	HNH endonuclease
ECDH1ME8569_RS02125	COG3248	Nucleoside-binding outer membrane protein
ECDH1ME8569_RS02130	COG4238	major outer membrane lipoprotein
ECDH1ME8569_RS02140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECDH1ME8569_RS02140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECDH1ME8569_RS02155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ECDH1ME8569_RS02160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ECDH1ME8569_RS02165	COG0667	Aldo Keto reductase
ECDH1ME8569_RS02175	COG0142	geranyltranstransferase activity
ECDH1ME8569_RS02190	COG0693	protein deglycase activity
ECDH1ME8569_RS02195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECDH1ME8569_RS02205	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS02215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ECDH1ME8569_RS02220	COG1845	cytochrome c oxidase, subunit III
ECDH1ME8569_RS02225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECDH1ME8569_RS02230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ECDH1ME8569_RS02235	COG2223	nitrite transmembrane transporter activity
ECDH1ME8569_RS02240	COG3056	Lipoprotein
ECDH1ME8569_RS02245	COG0271	Belongs to the BolA IbaG family
ECDH1ME8569_RS02270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ECDH1ME8569_RS02275	COG0776	regulation of translation
ECDH1ME8569_RS02280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECDH1ME8569_RS02285	COG1555	photosystem II stabilization
ECDH1ME8569_RS02290	COG0824	Thioesterase
ECDH1ME8569_RS02300	COG4533	DNA binding
ECDH1ME8569_RS02310	COG1522	sequence-specific DNA binding
ECDH1ME8569_RS02315	COG1132	(ABC) transporter
ECDH1ME8569_RS02320	COG1132	(ABC) transporter
ECDH1ME8569_RS02325	COG0347	Belongs to the P(II) protein family
ECDH1ME8569_RS02330	COG0004	ammonium transporteR
ECDH1ME8569_RS02335	COG1946	Acyl-CoA thioesterase
ECDH1ME8569_RS02340	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ECDH1ME8569_RS02345	COG3695	enzyme binding
ECDH1ME8569_RS02350	COG5507	3-demethylubiquinone-9 3-methyltransferase
ECDH1ME8569_RS02355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECDH1ME8569_RS02365	COG0110	maltose O-acetyltransferase activity
ECDH1ME8569_RS02380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECDH1ME8569_RS02385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECDH1ME8569_RS02390	COG1309	transcriptional regulator
ECDH1ME8569_RS02395	COG1196	nuclear chromosome segregation
ECDH1ME8569_RS02395	COG3264	Mechanosensitive ion channel
ECDH1ME8569_RS02410	COG3923	Primosomal replication protein n
ECDH1ME8569_RS02415	COG2832	Protein of unknown function (DUF454)
ECDH1ME8569_RS02425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECDH1ME8569_RS02460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS02465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECDH1ME8569_RS02465	COG4651	solute:proton antiporter activity
ECDH1ME8569_RS02470	COG2223	nitrite transmembrane transporter activity
ECDH1ME8569_RS02475	COG0737	Belongs to the 5'-nucleotidase family
ECDH1ME8569_RS02480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECDH1ME8569_RS02485	COG3735	TraB family
ECDH1ME8569_RS02490	COG3093	addiction module antidote protein HigA
ECDH1ME8569_RS02495	COG2217	Heavy metal translocating P-type atpase
ECDH1ME8569_RS02500	COG2066	Belongs to the glutaminase family
ECDH1ME8569_RS02505	COG0531	amino acid
ECDH1ME8569_RS02510	COG0789	Transcriptional regulator
ECDH1ME8569_RS02515	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECDH1ME8569_RS02520	COG0330	HflC and HflK could
ECDH1ME8569_RS02525	COG4619	ABC transporter
ECDH1ME8569_RS02530	COG0390	transport system, permease component
ECDH1ME8569_RS02535	COG3118	belongs to the thioredoxin family
ECDH1ME8569_RS02540	COG0300	oxidoreductase activity
ECDH1ME8569_RS02545	COG2755	lipolytic protein G-D-S-L family
ECDH1ME8569_RS02550	COG4181	ATPase activity
ECDH1ME8569_RS02555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ECDH1ME8569_RS02560	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS02570	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS02580	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS02590	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS02600	COG1414	Transcriptional regulator
ECDH1ME8569_RS02605	COG3960	tartronate-semialdehyde synthase activity
ECDH1ME8569_RS02610	COG3622	Belongs to the hyi family
ECDH1ME8569_RS02615	COG2084	Dehydrogenase
ECDH1ME8569_RS02620	COG1953	Uracil, thiamine, allantoin
ECDH1ME8569_RS02630	COG2233	PERMEase
ECDH1ME8569_RS02635	COG1929	Belongs to the glycerate kinase type-1 family
ECDH1ME8569_RS02640	COG3257	ureidoglycine aminohydrolase activity
ECDH1ME8569_RS02645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECDH1ME8569_RS02650	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECDH1ME8569_RS02655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECDH1ME8569_RS02660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECDH1ME8569_RS02670	COG0549	Belongs to the carbamate kinase family
ECDH1ME8569_RS02675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ECDH1ME8569_RS02680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ECDH1ME8569_RS02690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECDH1ME8569_RS02700	COG1988	membrane-bound metal-dependent
ECDH1ME8569_RS02705	COG2501	S4 domain
ECDH1ME8569_RS02715	COG3539	Fimbrial protein
ECDH1ME8569_RS02720	COG3121	Chaperone
ECDH1ME8569_RS02725	COG3188	usher protein
ECDH1ME8569_RS02730	COG3539	Fimbrial protein
ECDH1ME8569_RS02735	COG3539	Fimbrial protein
ECDH1ME8569_RS02740	COG2197	response regulator
ECDH1ME8569_RS02750	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS02770	COG3772	lysozyme
ECDH1ME8569_RS02790	COG5562	phage envelope protein
ECDH1ME8569_RS02810	COG4220	transposase activity
ECDH1ME8569_RS02820	COG0500	methyltransferase
ECDH1ME8569_RS02830	COG2207	Transcriptional regulator
ECDH1ME8569_RS02835	COG4571	Outer membrane protease
ECDH1ME8569_RS02845	COG2207	Transcriptional regulator
ECDH1ME8569_RS02855	COG4783	chaperone-mediated protein folding
ECDH1ME8569_RS02860	COG1215	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS02865	COG5002	protein histidine kinase activity
ECDH1ME8569_RS02870	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS02875	COG1538	Outer membrane efflux protein
ECDH1ME8569_RS02880	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECDH1ME8569_RS02885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECDH1ME8569_RS02890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECDH1ME8569_RS02895	COG1113	amino acid transport
ECDH1ME8569_RS02900	COG0668	transmembrane transport
ECDH1ME8569_RS02905	COG0778	Nitroreductase
ECDH1ME8569_RS02910	COG2315	Protein conserved in bacteria
ECDH1ME8569_RS02935	COG3385	transposase activity
ECDH1ME8569_RS02940	COG2977	Belongs to the P-Pant transferase superfamily
ECDH1ME8569_RS02945	COG4771	TonB-dependent receptor
ECDH1ME8569_RS02950	COG2382	esterase
ECDH1ME8569_RS02955	COG3251	PFAM MbtH domain protein
ECDH1ME8569_RS02960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ECDH1ME8569_RS02960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ECDH1ME8569_RS02965	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECDH1ME8569_RS02970	COG1120	ATPase activity
ECDH1ME8569_RS02975	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECDH1ME8569_RS02980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECDH1ME8569_RS02990	COG4592	Periplasmic binding protein
ECDH1ME8569_RS02995	COG1169	isochorismate synthase
ECDH1ME8569_RS03000	COG1021	2,3-dihydroxybenzoate-AMP ligase
ECDH1ME8569_RS03005	COG3433	isochorismatase activity
ECDH1ME8569_RS03005	COG1535	isochorismatase
ECDH1ME8569_RS03010	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS03015	COG2050	protein possibly involved in aromatic compounds catabolism
ECDH1ME8569_RS03020	COG1966	Carbon starvation protein
ECDH1ME8569_RS03025	COG2879	small protein
ECDH1ME8569_RS03030	COG0371	Dehydrogenase
ECDH1ME8569_RS03035	COG0436	Aminotransferase
ECDH1ME8569_RS03040	COG1475	DNA binding
ECDH1ME8569_RS03045	COG3969	phosphoadenosine phosphosulfate
ECDH1ME8569_RS03050	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS03055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECDH1ME8569_RS03060	COG0450	alkyl hydroperoxide reductase
ECDH1ME8569_RS03065	COG3634	alkyl hydroperoxide reductase activity
ECDH1ME8569_RS03070	COG0589	response to stress
ECDH1ME8569_RS03075	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS03085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECDH1ME8569_RS03090	COG3719	Belongs to the RNase T2 family
ECDH1ME8569_RS03095	COG0471	metal ion transport
ECDH1ME8569_RS03110	COG3051	citrate lyase alpha subunit
ECDH1ME8569_RS03115	COG2301	Belongs to the HpcH HpaI aldolase family
ECDH1ME8569_RS03125	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ECDH1ME8569_RS03130	COG3290	protein histidine kinase activity
ECDH1ME8569_RS03135	COG4565	transcriptional regulatory protein
ECDH1ME8569_RS03140	COG3069	C4-dicarboxylate transmembrane transporter activity
ECDH1ME8569_RS03165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECDH1ME8569_RS03175	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS03195	COG1686	Belongs to the peptidase S11 family
ECDH1ME8569_RS03200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECDH1ME8569_RS03205	COG0772	Belongs to the SEDS family
ECDH1ME8569_RS03210	COG0768	penicillin binding
ECDH1ME8569_RS03220	COG0799	negative regulation of ribosome biogenesis
ECDH1ME8569_RS03225	COG0406	alpha-ribazole phosphatase activity
ECDH1ME8569_RS03235	COG1466	dna polymerase III delta subunit
ECDH1ME8569_RS03250	COG2888	peptidyl-tyrosine sulfation
ECDH1ME8569_RS03255	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECDH1ME8569_RS03265	COG2214	Heat shock protein DnaJ domain protein
ECDH1ME8569_RS03270	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECDH1ME8569_RS03280	COG2214	Heat shock protein DnaJ domain protein
ECDH1ME8569_RS03285	COG0443	Heat shock 70 kDa protein
ECDH1ME8569_RS03295	COG1126	abc transporter atp-binding protein
ECDH1ME8569_RS03300	COG0765	amino acid transport
ECDH1ME8569_RS03305	COG0765	amino acid transport
ECDH1ME8569_RS03310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS03320	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ECDH1ME8569_RS03325	COG4535	Mg2 and Co2 transporter CorC
ECDH1ME8569_RS03335	COG1702	phosphate starvation-inducible protein PhoH
ECDH1ME8569_RS03345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECDH1ME8569_RS03385	COG0367	asparagine synthase
ECDH1ME8569_RS03390	COG0647	UMP catabolic process
ECDH1ME8569_RS03395	COG1940	carbohydrate kinase activity
ECDH1ME8569_RS03395	COG1846	Transcriptional regulator
ECDH1ME8569_RS03400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECDH1ME8569_RS03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS03410	COG1263	PTS System
ECDH1ME8569_RS03410	COG2190	(PTS) system
ECDH1ME8569_RS03430	COG0735	belongs to the Fur family
ECDH1ME8569_RS03445	COG0716	FMN binding
ECDH1ME8569_RS03455	COG0596	Alpha beta hydrolase
ECDH1ME8569_RS03460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ECDH1ME8569_RS03465	COG0033	Phosphoglucomutase
ECDH1ME8569_RS03485	COG0531	amino acid
ECDH1ME8569_RS03490	COG1982	Orn Lys Arg decarboxylase major
ECDH1ME8569_RS03500	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS03505	COG2205	protein histidine kinase activity
ECDH1ME8569_RS03535	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS03545	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS03555	COG5433	transposase activity
ECDH1ME8569_RS03565	COG3272	Protein of unknown function (DUF1722)
ECDH1ME8569_RS03570	COG0415	Belongs to the DNA photolyase family
ECDH1ME8569_RS03575	COG3104	oligopeptide transport
ECDH1ME8569_RS03580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ECDH1ME8569_RS03585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ECDH1ME8569_RS03590	COG1984	allophanate hydrolase subunit 2
ECDH1ME8569_RS03605	COG3180	Ammonia monooxygenase
ECDH1ME8569_RS03610	COG3539	Fimbrial protein
ECDH1ME8569_RS03615	COG3121	Chaperone
ECDH1ME8569_RS03620	COG3188	usher protein
ECDH1ME8569_RS03625	COG3539	Fimbrial protein
ECDH1ME8569_RS03630	COG0372	Belongs to the citrate synthase family
ECDH1ME8569_RS03640	COG2009	succinate dehydrogenase
ECDH1ME8569_RS03645	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ECDH1ME8569_RS03650	COG1053	succinate dehydrogenase
ECDH1ME8569_RS03655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECDH1ME8569_RS03665	COG0567	Dehydrogenase, E1 component
ECDH1ME8569_RS03670	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECDH1ME8569_RS03680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECDH1ME8569_RS03685	COG2188	Transcriptional regulator
ECDH1ME8569_RS03690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS03690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS03690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS03695	COG0383	alpha-mannosidase activity
ECDH1ME8569_RS03705	COG1271	oxidase subunit
ECDH1ME8569_RS03710	COG1294	oxidase, subunit
ECDH1ME8569_RS03715	COG4890	Cyd operon protein YbgT
ECDH1ME8569_RS03720	COG3790	cyd operon protein YbgE
ECDH1ME8569_RS03725	COG0824	Thioesterase
ECDH1ME8569_RS03730	COG0811	peptide transport
ECDH1ME8569_RS03735	COG0848	biopolymer transport protein
ECDH1ME8569_RS03740	COG3064	Membrane
ECDH1ME8569_RS03750	COG2885	chlorophyll binding
ECDH1ME8569_RS03755	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ECDH1ME8569_RS03800	COG3201	nicotinamide mononucleotide transporter
ECDH1ME8569_RS03805	COG1230	cation diffusion facilitator family transporter
ECDH1ME8569_RS03820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECDH1ME8569_RS03830	COG2017	converts alpha-aldose to the beta-anomer
ECDH1ME8569_RS03840	COG1085	galactose-1-phosphate uridylyltransferase
ECDH1ME8569_RS03845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ECDH1ME8569_RS03850	COG1119	ATPase activity
ECDH1ME8569_RS03855	COG2005	Transcriptional regulator
ECDH1ME8569_RS03855	COG3585	molybdate ion transport
ECDH1ME8569_RS03865	COG0725	ABC transporter, periplasmic molybdate-binding protein
ECDH1ME8569_RS03870	COG4149	molybdate abc transporter
ECDH1ME8569_RS03875	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ECDH1ME8569_RS03880	COG0561	phosphatase activity
ECDH1ME8569_RS03890	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS03895	COG2828	Protein conserved in bacteria
ECDH1ME8569_RS03900	COG0471	metal ion transport
ECDH1ME8569_RS03905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECDH1ME8569_RS03910	COG4677	pectinesterase activity
ECDH1ME8569_RS03915	COG1881	PFAM PEBP family protein
ECDH1ME8569_RS03920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ECDH1ME8569_RS03935	COG2226	methyltransferase
ECDH1ME8569_RS03940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECDH1ME8569_RS03950	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ECDH1ME8569_RS03965	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECDH1ME8569_RS03975	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ECDH1ME8569_RS03980	COG0314	molybdopterin synthase activity
ECDH1ME8569_RS03985	COG0670	Belongs to the BI1 family
ECDH1ME8569_RS03990	COG0670	Belongs to the BI1 family
ECDH1ME8569_RS03995	COG0392	lysyltransferase activity
ECDH1ME8569_RS04000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECDH1ME8569_RS04005	COG3568	Endonuclease Exonuclease Phosphatase
ECDH1ME8569_RS04015	COG0842	Transport permease protein
ECDH1ME8569_RS04020	COG0842	Transport permease protein
ECDH1ME8569_RS04025	COG1131	(ABC) transporter
ECDH1ME8569_RS04035	COG1309	transcriptional regulator
ECDH1ME8569_RS04040	COG0513	Belongs to the DEAD box helicase family
ECDH1ME8569_RS04045	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ECDH1ME8569_RS04050	COG1199	ATP-dependent helicase activity
ECDH1ME8569_RS04055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECDH1ME8569_RS04060	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECDH1ME8569_RS04070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECDH1ME8569_RS04080	COG4774	siderophore transport
ECDH1ME8569_RS04095	COG0668	transmembrane transport
ECDH1ME8569_RS04100	COG1126	abc transporter atp-binding protein
ECDH1ME8569_RS04105	COG0765	amino acid transport
ECDH1ME8569_RS04110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS04125	COG5006	permease, DMT superfamily
ECDH1ME8569_RS04130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECDH1ME8569_RS04135	COG2194	sulfuric ester hydrolase activity
ECDH1ME8569_RS04145	COG1321	iron dependent repressor
ECDH1ME8569_RS04150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECDH1ME8569_RS04155	COG1376	ErfK ybiS ycfS ynhG family protein
ECDH1ME8569_RS04160	COG0488	(ABC) transporter
ECDH1ME8569_RS04170	COG0561	phosphatase activity
ECDH1ME8569_RS04175	COG1882	Formate acetyltransferase
ECDH1ME8569_RS04180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECDH1ME8569_RS04185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECDH1ME8569_RS04190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECDH1ME8569_RS04195	COG0303	'Molybdopterin
ECDH1ME8569_RS04200	COG1446	asparaginase
ECDH1ME8569_RS04205	COG4172	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS04220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECDH1ME8569_RS04225	COG2200	EAL domain
ECDH1ME8569_RS04230	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS04245	COG2133	pyrroloquinoline quinone binding
ECDH1ME8569_RS04250	COG0625	glutathione transferase activity
ECDH1ME8569_RS04255	COG1686	Belongs to the peptidase S11 family
ECDH1ME8569_RS04260	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS04265	COG0671	phosphoesterase, PA-phosphatase related
ECDH1ME8569_RS04270	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS04280	COG0561	phosphatase activity
ECDH1ME8569_RS04285	COG0738	Major facilitator superfamily
ECDH1ME8569_RS04290	COG3226	Transcriptional regulator
ECDH1ME8569_RS04305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECDH1ME8569_RS04315	COG0778	Nitroreductase
ECDH1ME8569_RS04335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECDH1ME8569_RS04340	COG3842	ATPase activity
ECDH1ME8569_RS04345	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECDH1ME8569_RS04350	COG1177	transmembrane transport
ECDH1ME8569_RS04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS04370	COG4160	amino acid transport
ECDH1ME8569_RS04375	COG4215	(ABC) transporter
ECDH1ME8569_RS04380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS04385	COG1126	abc transporter atp-binding protein
ECDH1ME8569_RS04400	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECDH1ME8569_RS04405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECDH1ME8569_RS04410	COG0702	epimerase
ECDH1ME8569_RS04415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ECDH1ME8569_RS04420	COG0028	Belongs to the TPP enzyme family
ECDH1ME8569_RS04425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECDH1ME8569_RS04435	COG2431	L-lysine efflux transmembrane transporter activity
ECDH1ME8569_RS04450	COG3593	DNA synthesis involved in DNA repair
ECDH1ME8569_RS04455	COG2990	Protein conserved in bacteria
ECDH1ME8569_RS04460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECDH1ME8569_RS04465	COG1136	(ABC) transporter
ECDH1ME8569_RS04465	COG0577	efflux transmembrane transporter activity
ECDH1ME8569_RS04470	COG1278	Cold shock
ECDH1ME8569_RS04480	COG0542	response to heat
ECDH1ME8569_RS04500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ECDH1ME8569_RS04505	COG4988	ABC transporter
ECDH1ME8569_RS04510	COG0492	ferredoxin-NADP+ reductase activity
ECDH1ME8569_RS04515	COG1522	sequence-specific DNA binding
ECDH1ME8569_RS04520	COG1674	ftsk spoiiie
ECDH1ME8569_RS04520	COG1178	ABC-type Fe3 transport system permease component
ECDH1ME8569_RS04530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ECDH1ME8569_RS04540	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS04545	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS04550	COG3302	dmso reductase anchor subunit
ECDH1ME8569_RS04555	COG1335	isochorismatase
ECDH1ME8569_RS04565	COG0531	amino acid
ECDH1ME8569_RS04570	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS04575	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECDH1ME8569_RS04580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECDH1ME8569_RS04585	COG1882	Formate acetyltransferase
ECDH1ME8569_RS04590	COG2116	formate transmembrane transporter activity
ECDH1ME8569_RS04595	COG1944	ATP diphosphatase activity
ECDH1ME8569_RS04600	COG2323	membrane
ECDH1ME8569_RS04615	COG0501	Belongs to the peptidase M48B family
ECDH1ME8569_RS04625	COG0539	negative regulation of cytoplasmic translation
ECDH1ME8569_RS04635	COG0658	competence protein
ECDH1ME8569_RS04635	COG2333	competence protein COMEC
ECDH1ME8569_RS04640	COG1132	(ABC) transporter
ECDH1ME8569_RS04645	COG1663	tetraacyldisaccharide 4'-kinase activity
ECDH1ME8569_RS04650	COG3214	Protein conserved in bacteria
ECDH1ME8569_RS04665	COG3173	Aminoglycoside phosphotransferase
ECDH1ME8569_RS04670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECDH1ME8569_RS04675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECDH1ME8569_RS04685	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ECDH1ME8569_RS04695	COG2989	Protein conserved in bacteria
ECDH1ME8569_RS04700	COG3108	Peptidase M15
ECDH1ME8569_RS04705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECDH1ME8569_RS04710	COG1448	Aminotransferase
ECDH1ME8569_RS04735	COG0308	aminopeptidase N
ECDH1ME8569_RS04740	COG1116	anion transmembrane transporter activity
ECDH1ME8569_RS04745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECDH1ME8569_RS04755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECDH1ME8569_RS04760	COG0431	NADPH-dependent FMN reductase
ECDH1ME8569_RS04765	COG3539	Fimbrial protein
ECDH1ME8569_RS04770	COG3121	Chaperone
ECDH1ME8569_RS04775	COG3188	usher protein
ECDH1ME8569_RS04780	COG3539	Fimbrial protein
ECDH1ME8569_RS04785	COG3539	Fimbrial protein
ECDH1ME8569_RS04790	COG3539	Fimbrial protein
ECDH1ME8569_RS04795	COG3121	Chaperone
ECDH1ME8569_RS04810	COG3217	Mosc domain protein beta barrel domain protein
ECDH1ME8569_RS04810	COG0633	Ferredoxin
ECDH1ME8569_RS04820	COG0488	(ABC) transporter
ECDH1ME8569_RS04825	COG2995	paraquat-inducible protein a
ECDH1ME8569_RS04830	COG3008	intermembrane lipid transfer
ECDH1ME8569_RS04830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECDH1ME8569_RS04835	COG3009	Protein conserved in bacteria
ECDH1ME8569_RS04840	COG3130	regulation of translation
ECDH1ME8569_RS04850	COG1067	ATP-dependent peptidase activity
ECDH1ME8569_RS04860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECDH1ME8569_RS04860	COG2885	chlorophyll binding
ECDH1ME8569_RS04875	COG3070	regulator of competence-specific genes
ECDH1ME8569_RS04880	COG1289	transmembrane transporter activity
ECDH1ME8569_RS04885	COG3304	Inner membrane component domain
ECDH1ME8569_RS04890	COG0210	DNA helicase
ECDH1ME8569_RS04925	COG1832	CoA-binding protein
ECDH1ME8569_RS04940	COG1254	Belongs to the acylphosphatase family
ECDH1ME8569_RS04945	COG2920	part of a sulfur-relay system
ECDH1ME8569_RS04950	COG0670	Belongs to the BI1 family
ECDH1ME8569_RS04960	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECDH1ME8569_RS04965	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECDH1ME8569_RS04970	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ECDH1ME8569_RS04975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECDH1ME8569_RS04980	COG1999	signal sequence binding
ECDH1ME8569_RS04985	COG1773	rubredoxin
ECDH1ME8569_RS04990	COG1271	oxidase subunit
ECDH1ME8569_RS04995	COG1294	oxidase, subunit
ECDH1ME8569_RS05010	COG0489	protein tyrosine kinase activity
ECDH1ME8569_RS05010	COG3206	protein involved in exopolysaccharide biosynthesis
ECDH1ME8569_RS05015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECDH1ME8569_RS05020	COG1596	polysaccharide export
ECDH1ME8569_RS05025	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECDH1ME8569_RS05050	COG1662	PFAM IS1 transposase
ECDH1ME8569_RS05055	COG1278	Cold shock
ECDH1ME8569_RS05060	COG1278	Cold shock
ECDH1ME8569_RS05075	COG0348	domain, Protein
ECDH1ME8569_RS05080	COG2205	protein histidine kinase activity
ECDH1ME8569_RS05080	COG2198	Histidine kinase
ECDH1ME8569_RS05080	COG0784	Response regulator, receiver
ECDH1ME8569_RS05085	COG1879	ABC-type sugar transport system periplasmic component
ECDH1ME8569_RS05090	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS05095	COG3005	denitrification pathway
ECDH1ME8569_RS05100	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS05105	COG3381	protein complex oligomerization
ECDH1ME8569_RS05145	COG3729	General stress protein
ECDH1ME8569_RS05150	COG2233	PERMEase
ECDH1ME8569_RS05185	COG1309	transcriptional regulator
ECDH1ME8569_RS05190	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECDH1ME8569_RS05190	COG0506	proline dehydrogenase activity
ECDH1ME8569_RS05190	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECDH1ME8569_RS05200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECDH1ME8569_RS05215	COG2822	iron ion transport
ECDH1ME8569_RS05220	COG2837	iron assimilation
ECDH1ME8569_RS05230	COG1702	phosphate starvation-inducible protein PhoH
ECDH1ME8569_RS05235	COG3658	cytochrome
ECDH1ME8569_RS05240	COG1215	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS05245	COG1649	PFAM Uncharacterised BCR, COG1649
ECDH1ME8569_RS05245	COG0726	polysaccharide deacetylase
ECDH1ME8569_RS05250	COG0457	Tetratricopeptide repeat
ECDH1ME8569_RS05265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECDH1ME8569_RS05270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECDH1ME8569_RS05295	COG2943	transferase activity, transferring hexosyl groups
ECDH1ME8569_RS05300	COG5645	(Lipo)protein
ECDH1ME8569_RS05320	COG1560	Kdo2-lipid A biosynthetic process
ECDH1ME8569_RS05330	COG2353	YceI-like domain
ECDH1ME8569_RS05335	COG3038	cytochrome b561
ECDH1ME8569_RS05370	COG2999	glutathione oxidoreductase activity
ECDH1ME8569_RS05380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECDH1ME8569_RS05390	COG0673	inositol 2-dehydrogenase activity
ECDH1ME8569_RS05395	COG0728	peptidoglycan biosynthetic process
ECDH1ME8569_RS05400	COG3418	PFAM FlgN family protein
ECDH1ME8569_RS05405	COG2747	anti-sigma28 factor FlgM
ECDH1ME8569_RS05410	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ECDH1ME8569_RS05415	COG1815	bacterial-type flagellum-dependent cell motility
ECDH1ME8569_RS05420	COG1558	bacterial-type flagellum-dependent cell motility
ECDH1ME8569_RS05425	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ECDH1ME8569_RS05430	COG1749	Flagellar hook protein flgE
ECDH1ME8569_RS05435	COG4787	bacterial-type flagellum-dependent cell motility
ECDH1ME8569_RS05440	COG4786	Flagellar basal body rod
ECDH1ME8569_RS05455	COG3951	Flagellar rod assembly protein muramidase FlgJ
ECDH1ME8569_RS05455	COG1705	Flagellar rod assembly protein muramidase FlgJ
ECDH1ME8569_RS05460	COG1256	bacterial-type flagellum assembly
ECDH1ME8569_RS05465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECDH1ME8569_RS05470	COG1530	ribonuclease E activity
ECDH1ME8569_RS05480	COG0564	pseudouridine synthase activity
ECDH1ME8569_RS05485	COG0424	maF-like protein
ECDH1ME8569_RS05490	COG1399	metal-binding, possibly nucleic acid-binding protein
ECDH1ME8569_RS05510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ECDH1ME8569_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS05525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECDH1ME8569_RS05530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECDH1ME8569_RS05535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ECDH1ME8569_RS05545	COG0470	DNA polymerase III
ECDH1ME8569_RS05550	COG0084	hydrolase, TatD family'
ECDH1ME8569_RS05555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS05555	COG1263	PTS System
ECDH1ME8569_RS05560	COG4773	Receptor
ECDH1ME8569_RS05565	COG0537	adenosine 5'-monophosphoramidase activity
ECDH1ME8569_RS05570	COG5633	Lipoprotein
ECDH1ME8569_RS05575	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ECDH1ME8569_RS05595	COG1252	NADH dehydrogenase
ECDH1ME8569_RS05600	COG3134	Outer membrane lipoprotein
ECDH1ME8569_RS05605	COG1309	transcriptional regulator
ECDH1ME8569_RS05615	COG1388	LysM domain
ECDH1ME8569_RS05615	COG1376	ErfK ybiS ycfS ynhG family protein
ECDH1ME8569_RS05620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ECDH1ME8569_RS05625	COG4763	Acyl-transferase
ECDH1ME8569_RS05630	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECDH1ME8569_RS05635	COG1136	(ABC) transporter
ECDH1ME8569_RS05640	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECDH1ME8569_RS05650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ECDH1ME8569_RS05655	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECDH1ME8569_RS05665	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECDH1ME8569_RS05670	COG1177	transmembrane transport
ECDH1ME8569_RS05680	COG3842	ATPase activity
ECDH1ME8569_RS05695	COG2850	peptidyl-arginine hydroxylation
ECDH1ME8569_RS05700	COG2205	protein histidine kinase activity
ECDH1ME8569_RS05705	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS05710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECDH1ME8569_RS05730	COG1187	pseudouridine synthase activity
ECDH1ME8569_RS05735	COG0538	isocitrate dehydrogenase activity
ECDH1ME8569_RS05740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECDH1ME8569_RS05760	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS05765	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS05780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECDH1ME8569_RS05785	COG4197	protein conserved in bacteria, prophage-related
ECDH1ME8569_RS05800	COG1802	Transcriptional regulator
ECDH1ME8569_RS05800	COG4626	Terminase
ECDH1ME8569_RS05810	COG4695	Portal protein
ECDH1ME8569_RS05815	COG3299	homolog of phage Mu protein gp47
ECDH1ME8569_RS05820	COG3778	Protein conserved in bacteria
ECDH1ME8569_RS05835	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECDH1ME8569_RS05845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECDH1ME8569_RS05850	COG1403	HNH endonuclease
ECDH1ME8569_RS05865	COG5562	phage envelope protein
ECDH1ME8569_RS05870	COG0789	Transcriptional regulator
ECDH1ME8569_RS05875	COG2200	EAL domain
ECDH1ME8569_RS05900	COG2200	EAL domain
ECDH1ME8569_RS05950	COG2894	cell division
ECDH1ME8569_RS05980	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECDH1ME8569_RS05995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECDH1ME8569_RS06000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ECDH1ME8569_RS06005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ECDH1ME8569_RS06020	COG2719	SpoVR family
ECDH1ME8569_RS06030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECDH1ME8569_RS06040	COG1619	proteins homologs of microcin C7 resistance protein MccF
ECDH1ME8569_RS06050	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ECDH1ME8569_RS06055	COG2261	transglycosylase associated protein
ECDH1ME8569_RS06070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDH1ME8569_RS06070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS06070	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ECDH1ME8569_RS06075	COG1461	Dihydroxyacetone kinase
ECDH1ME8569_RS06080	COG2376	Dihydroxyacetone kinase
ECDH1ME8569_RS06085	COG3284	Transcriptional regulator
ECDH1ME8569_RS06090	COG3468	outer membrane autotransporter barrel domain protein
ECDH1ME8569_RS06100	COG0012	GTP binding
ECDH1ME8569_RS06115	COG0659	secondary active sulfate transmembrane transporter activity
ECDH1ME8569_RS06120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ECDH1ME8569_RS06145	COG2890	protein-(glutamine-N5) methyltransferase activity
ECDH1ME8569_RS06150	COG3094	Invasion gene expression up-regulator, SirB
ECDH1ME8569_RS06155	COG2912	Transglutaminase-like superfamily
ECDH1ME8569_RS06180	COG0387	Pfam Sodium calcium exchanger
ECDH1ME8569_RS06185	COG4572	Cation transport regulator
ECDH1ME8569_RS06190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ECDH1ME8569_RS06195	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECDH1ME8569_RS06200	COG4932	domain protein
ECDH1ME8569_RS06205	COG2197	response regulator
ECDH1ME8569_RS06210	COG3850	Histidine kinase
ECDH1ME8569_RS06220	COG2223	nitrite transmembrane transporter activity
ECDH1ME8569_RS06230	COG1140	nitrate reductase beta subunit
ECDH1ME8569_RS06235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECDH1ME8569_RS06240	COG2181	nitrate reductase activity
ECDH1ME8569_RS06260	COG0788	formyltetrahydrofolate deformylase activity
ECDH1ME8569_RS06270	COG1752	Esterase of the alpha-beta hydrolase superfamily
ECDH1ME8569_RS06280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ECDH1ME8569_RS06290	COG1435	thymidine kinase activity
ECDH1ME8569_RS06305	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS06305	COG1454	alcohol dehydrogenase
ECDH1ME8569_RS06310	COG2095	MarC family integral membrane protein
ECDH1ME8569_RS06320	COG4166	transmembrane transport
ECDH1ME8569_RS06335	COG4166	transmembrane transport
ECDH1ME8569_RS06340	COG0601	transmembrane transport
ECDH1ME8569_RS06345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECDH1ME8569_RS06350	COG0444	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS06355	COG4608	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS06375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECDH1ME8569_RS06380	COG2350	Protein conserved in bacteria
ECDH1ME8569_RS06385	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ECDH1ME8569_RS06390	COG1607	acyl-coa hydrolase
ECDH1ME8569_RS06405	COG3047	cAMP biosynthetic process
ECDH1ME8569_RS06410	COG3685	Protein conserved in bacteria
ECDH1ME8569_RS06415	COG3685	Protein conserved in bacteria
ECDH1ME8569_RS06420	COG3729	General stress protein
ECDH1ME8569_RS06435	COG0134	indole-3-glycerol-phosphate synthase activity
ECDH1ME8569_RS06435	COG0135	phosphoribosylanthranilate isomerase activity
ECDH1ME8569_RS06440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECDH1ME8569_RS06440	COG0512	Glutamine amidotransferase of anthranilate synthase
ECDH1ME8569_RS06445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECDH1ME8569_RS06450	COG0613	PHP domain protein
ECDH1ME8569_RS06455	COG0009	L-threonylcarbamoyladenylate synthase
ECDH1ME8569_RS06460	COG4907	membrane protein (DUF2207)
ECDH1ME8569_RS06465	COG1187	pseudouridine synthase activity
ECDH1ME8569_RS06470	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ECDH1ME8569_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS06485	COG0616	signal peptide processing
ECDH1ME8569_RS06500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECDH1ME8569_RS06505	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS06525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECDH1ME8569_RS06535	COG0671	phosphoesterase, PA-phosphatase related
ECDH1ME8569_RS06540	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ECDH1ME8569_RS06545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ECDH1ME8569_RS06555	COG0023	Translation Initiation Factor
ECDH1ME8569_RS06565	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS06575	COG5001	Diguanylate cyclase
ECDH1ME8569_RS06590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECDH1ME8569_RS06590	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECDH1ME8569_RS06595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECDH1ME8569_RS06600	COG2852	Protein conserved in bacteria
ECDH1ME8569_RS06605	COG4172	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS06610	COG4172	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS06615	COG4171	peptide transport system, permease
ECDH1ME8569_RS06620	COG4168	peptide transport system, permease
ECDH1ME8569_RS06625	COG4166	transmembrane transport
ECDH1ME8569_RS06640	COG0531	amino acid
ECDH1ME8569_RS06645	COG0174	glutamine synthetase
ECDH1ME8569_RS06650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ECDH1ME8569_RS06655	COG1396	sequence-specific DNA binding
ECDH1ME8569_RS06655	COG1917	Cupin 2, conserved barrel domain protein
ECDH1ME8569_RS06660	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS06665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECDH1ME8569_RS06670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECDH1ME8569_RS06675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ECDH1ME8569_RS06680	COG1842	Phage shock protein A
ECDH1ME8569_RS06690	COG1983	PspC domain protein
ECDH1ME8569_RS06700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECDH1ME8569_RS06705	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS06710	COG1653	transport
ECDH1ME8569_RS06715	COG1175	transmembrane transport
ECDH1ME8569_RS06720	COG0395	ABC-type sugar transport system, permease component
ECDH1ME8569_RS06725	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS06730	COG1082	Xylose isomerase domain protein TIM barrel
ECDH1ME8569_RS06735	COG0673	inositol 2-dehydrogenase activity
ECDH1ME8569_RS06740	COG1554	hydrolase, family 65, central catalytic
ECDH1ME8569_RS06745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECDH1ME8569_RS06760	COG1609	Transcriptional regulator
ECDH1ME8569_RS06765	COG3106	COG3106 Predicted ATPase
ECDH1ME8569_RS06775	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ECDH1ME8569_RS06780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ECDH1ME8569_RS06785	COG4948	Mandelate Racemase Muconate Lactonizing
ECDH1ME8569_RS06790	COG2866	Carboxypeptidase
ECDH1ME8569_RS06795	COG0702	epimerase
ECDH1ME8569_RS06800	COG1073	alpha beta
ECDH1ME8569_RS06805	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS06815	COG4166	transmembrane transport
ECDH1ME8569_RS06820	COG0668	transmembrane transport
ECDH1ME8569_RS06830	COG3182	Iron-regulated membrane protein
ECDH1ME8569_RS06835	COG0589	response to stress
ECDH1ME8569_RS06840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECDH1ME8569_RS06850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECDH1ME8569_RS06855	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ECDH1ME8569_RS06865	COG1473	amidohydrolase
ECDH1ME8569_RS06870	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS06880	COG2840	Smr protein MutS2
ECDH1ME8569_RS06885	COG3706	GGDEF domain
ECDH1ME8569_RS06900	COG0513	Belongs to the DEAD box helicase family
ECDH1ME8569_RS06910	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS06930	COG3723	Recombinational DNA repair protein, rece pathway
ECDH1ME8569_RS06935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECDH1ME8569_RS06965	COG4197	protein conserved in bacteria, prophage-related
ECDH1ME8569_RS06975	COG3756	Protein conserved in bacteria
ECDH1ME8569_RS06980	COG1484	DNA-dependent DNA replication
ECDH1ME8569_RS06985	COG1846	Transcriptional regulator
ECDH1ME8569_RS06995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECDH1ME8569_RS07000	COG1475	DNA binding
ECDH1ME8569_RS07015	COG1196	nuclear chromosome segregation
ECDH1ME8569_RS07025	COG3039	Transposase
ECDH1ME8569_RS07045	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECDH1ME8569_RS07050	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECDH1ME8569_RS07055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECDH1ME8569_RS07065	COG0589	response to stress
ECDH1ME8569_RS07070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECDH1ME8569_RS07075	COG0674	pyruvate-flavodoxin oxidoreductase activity
ECDH1ME8569_RS07075	COG1013	pyruvate-flavodoxin oxidoreductase activity
ECDH1ME8569_RS07075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECDH1ME8569_RS07075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ECDH1ME8569_RS07080	COG3042	response to heat
ECDH1ME8569_RS07085	COG3187	Heat shock protein
ECDH1ME8569_RS07090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECDH1ME8569_RS07095	COG2911	Protein conserved in bacteria
ECDH1ME8569_RS07105	COG3784	Protein of unknown function (DUF1318)
ECDH1ME8569_RS07110	COG2207	Transcriptional regulator
ECDH1ME8569_RS07115	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS07120	COG3733	amine oxidase
ECDH1ME8569_RS07125	COG2030	dehydratase
ECDH1ME8569_RS07125	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS07130	COG3396	Phenylacetate-CoA oxygenase
ECDH1ME8569_RS07135	COG3460	Phenylacetate-CoA oxygenase
ECDH1ME8569_RS07140	COG3396	Phenylacetate-CoA oxygenase
ECDH1ME8569_RS07145	COG2151	metal-sulfur cluster biosynthetic enzyme
ECDH1ME8569_RS07150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECDH1ME8569_RS07155	COG1024	Enoyl-CoA hydratase
ECDH1ME8569_RS07160	COG1024	Enoyl-CoA hydratase
ECDH1ME8569_RS07165	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECDH1ME8569_RS07170	COG2050	protein possibly involved in aromatic compounds catabolism
ECDH1ME8569_RS07175	COG0183	Belongs to the thiolase family
ECDH1ME8569_RS07180	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ECDH1ME8569_RS07185	COG3327	negative regulation of DNA-templated transcription, initiation
ECDH1ME8569_RS07190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECDH1ME8569_RS07210	COG2826	transposase and inactivated derivatives, IS30 family
ECDH1ME8569_RS07220	COG0667	Aldo Keto reductase
ECDH1ME8569_RS07230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECDH1ME8569_RS07235	COG4589	Belongs to the CDS family
ECDH1ME8569_RS07240	COG2267	carboxylic ester hydrolase activity
ECDH1ME8569_RS07245	COG0671	phosphoesterase, PA-phosphatase related
ECDH1ME8569_RS07245	COG2453	phosphatase
ECDH1ME8569_RS07255	COG1643	Atp-dependent helicase
ECDH1ME8569_RS07260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECDH1ME8569_RS07265	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS07270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECDH1ME8569_RS07275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECDH1ME8569_RS07280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECDH1ME8569_RS07285	COG3038	cytochrome b561
ECDH1ME8569_RS07300	COG0840	transmembrane signaling receptor activity
ECDH1ME8569_RS07305	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS07310	COG5383	Protein conserved in bacteria
ECDH1ME8569_RS07325	COG2841	Protein conserved in bacteria
ECDH1ME8569_RS07330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECDH1ME8569_RS07335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECDH1ME8569_RS07340	COG1275	C4-dicarboxylate transporter malic acid transport protein
ECDH1ME8569_RS07345	COG0500	methyltransferase
ECDH1ME8569_RS07365	COG0675	Transposase, IS605 OrfB family
ECDH1ME8569_RS07370	COG3135	benzoate transporter
ECDH1ME8569_RS07375	COG1396	sequence-specific DNA binding
ECDH1ME8569_RS07380	COG0826	peptidase U32
ECDH1ME8569_RS07390	COG1724	mRNA binding
ECDH1ME8569_RS07395	COG1598	PFAM Uncharacterised protein family UPF0150
ECDH1ME8569_RS07400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECDH1ME8569_RS07405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECDH1ME8569_RS07410	COG3842	ATPase activity
ECDH1ME8569_RS07415	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECDH1ME8569_RS07420	COG1177	transmembrane transport
ECDH1ME8569_RS07445	COG3238	Protein conserved in bacteria
ECDH1ME8569_RS07450	COG1247	-acetyltransferase
ECDH1ME8569_RS07455	COG2130	NADP-dependent
ECDH1ME8569_RS07460	COG1802	Transcriptional regulator
ECDH1ME8569_RS07465	COG4772	TonB-dependent receptor
ECDH1ME8569_RS07470	COG3391	amine dehydrogenase activity
ECDH1ME8569_RS07475	COG1113	amino acid transport
ECDH1ME8569_RS07480	COG0625	glutathione transferase activity
ECDH1ME8569_RS07490	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS07500	COG5433	transposase activity
ECDH1ME8569_RS07505	COG5433	transposase activity
ECDH1ME8569_RS07515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECDH1ME8569_RS07520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ECDH1ME8569_RS07525	COG0384	phenazine biosynthesis protein PhzF
ECDH1ME8569_RS07530	COG2181	nitrate reductase activity
ECDH1ME8569_RS07535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECDH1ME8569_RS07540	COG1140	nitrate reductase beta subunit
ECDH1ME8569_RS07545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECDH1ME8569_RS07550	COG2223	nitrite transmembrane transporter activity
ECDH1ME8569_RS07560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECDH1ME8569_RS07565	COG0697	spore germination
ECDH1ME8569_RS07570	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS07570	COG3383	formate dehydrogenase (NAD+) activity
ECDH1ME8569_RS07575	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS07575	COG3383	formate dehydrogenase (NAD+) activity
ECDH1ME8569_RS07580	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS07585	COG2864	formate dehydrogenase
ECDH1ME8569_RS07590	COG3093	addiction module antidote protein HigA
ECDH1ME8569_RS07595	COG1064	alcohol dehydrogenase
ECDH1ME8569_RS07615	COG1764	response to oxidative stress
ECDH1ME8569_RS07620	COG4608	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS07625	COG0444	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS07630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECDH1ME8569_RS07635	COG0601	transmembrane transport
ECDH1ME8569_RS07640	COG0747	negative chemotaxis
ECDH1ME8569_RS07645	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ECDH1ME8569_RS07650	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS07650	COG2202	Pas domain
ECDH1ME8569_RS07650	COG2200	EAL domain
ECDH1ME8569_RS07655	COG3706	GGDEF domain
ECDH1ME8569_RS07660	COG1649	PFAM Uncharacterised BCR, COG1649
ECDH1ME8569_RS07665	COG0531	amino acid
ECDH1ME8569_RS07670	COG0076	glutamate decarboxylase activity
ECDH1ME8569_RS07680	COG0612	Peptidase, M16
ECDH1ME8569_RS07685	COG4771	TonB-dependent receptor
ECDH1ME8569_RS07690	COG4178	(ABC) transporter
ECDH1ME8569_RS07695	COG0641	radical SAM
ECDH1ME8569_RS07700	COG3119	arylsulfatase activity
ECDH1ME8569_RS07705	COG2207	Transcriptional regulator
ECDH1ME8569_RS07715	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS07720	COG3539	Fimbrial protein
ECDH1ME8569_RS07725	COG3539	Fimbrial protein
ECDH1ME8569_RS07730	COG3539	Fimbrial protein
ECDH1ME8569_RS07735	COG3188	usher protein
ECDH1ME8569_RS07740	COG4977	sequence-specific DNA binding
ECDH1ME8569_RS07745	COG3550	peptidyl-serine autophosphorylation
ECDH1ME8569_RS07750	COG1396	sequence-specific DNA binding
ECDH1ME8569_RS07760	COG3210	domain, Protein
ECDH1ME8569_RS07760	COG2911	Protein conserved in bacteria
ECDH1ME8569_RS07810	COG3781	membrane
ECDH1ME8569_RS07825	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS07835	COG2066	Belongs to the glutaminase family
ECDH1ME8569_RS07840	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS07845	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS07865	COG1846	Transcriptional regulator
ECDH1ME8569_RS07870	COG4977	sequence-specific DNA binding
ECDH1ME8569_RS07880	COG0697	spore germination
ECDH1ME8569_RS07885	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS07895	COG3706	GGDEF domain
ECDH1ME8569_RS07900	COG3111	PFAM Bacterial OB fold (BOF) protein
ECDH1ME8569_RS07905	COG1546	Belongs to the CinA family
ECDH1ME8569_RS07910	COG0339	signal peptide processing
ECDH1ME8569_RS07915	COG4221	oxidoreductase activity
ECDH1ME8569_RS07920	COG1802	Transcriptional regulator
ECDH1ME8569_RS07930	COG0246	Mannitol dehydrogenase
ECDH1ME8569_RS07935	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS07945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECDH1ME8569_RS07950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECDH1ME8569_RS07955	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECDH1ME8569_RS07960	COG4220	transposase activity
ECDH1ME8569_RS07970	COG5562	phage envelope protein
ECDH1ME8569_RS07985	COG1278	Cold shock
ECDH1ME8569_RS07995	COG3772	lysozyme
ECDH1ME8569_RS08010	COG1278	Cold shock
ECDH1ME8569_RS08015	COG1278	Cold shock
ECDH1ME8569_RS08020	COG0484	heat shock protein binding
ECDH1ME8569_RS08025	COG1403	HNH endonuclease
ECDH1ME8569_RS08045	COG2026	Addiction module toxin, RelE StbE family
ECDH1ME8569_RS08050	COG3077	Addiction module antitoxin, RelB DinJ family
ECDH1ME8569_RS08070	COG1396	sequence-specific DNA binding
ECDH1ME8569_RS08110	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS08115	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS08120	COG4948	Mandelate Racemase Muconate Lactonizing
ECDH1ME8569_RS08135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECDH1ME8569_RS08150	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS08155	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS08160	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS08165	COG3302	dmso reductase anchor subunit
ECDH1ME8569_RS08170	COG3381	protein complex oligomerization
ECDH1ME8569_RS08180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECDH1ME8569_RS08185	COG1940	carbohydrate kinase activity
ECDH1ME8569_RS08190	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS08195	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS08210	COG3591	Belongs to the peptidase S1B family
ECDH1ME8569_RS08225	COG0628	permease
ECDH1ME8569_RS08230	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ECDH1ME8569_RS08235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ECDH1ME8569_RS08245	COG0531	amino acid
ECDH1ME8569_RS08255	COG3136	membrane protein required for alginate biosynthesis
ECDH1ME8569_RS08260	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS08265	COG2205	protein histidine kinase activity
ECDH1ME8569_RS08275	COG0114	fumarate hydratase activity
ECDH1ME8569_RS08280	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECDH1ME8569_RS08280	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECDH1ME8569_RS08285	COG1482	cell wall glycoprotein biosynthetic process
ECDH1ME8569_RS08290	COG5339	Protein conserved in bacteria
ECDH1ME8569_RS08300	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS08305	COG3250	beta-galactosidase activity
ECDH1ME8569_RS08310	COG1309	transcriptional regulator
ECDH1ME8569_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS08320	COG1609	Transcriptional regulator
ECDH1ME8569_RS08325	COG1263	PTS System
ECDH1ME8569_RS08325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS08330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECDH1ME8569_RS08340	COG0673	inositol 2-dehydrogenase activity
ECDH1ME8569_RS08380	COG4659	FMN binding
ECDH1ME8569_RS08390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECDH1ME8569_RS08400	COG3104	oligopeptide transport
ECDH1ME8569_RS08405	COG0625	glutathione transferase activity
ECDH1ME8569_RS08410	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ECDH1ME8569_RS08425	COG3895	Periplasmic Protein
ECDH1ME8569_RS08435	COG3133	Outer membrane lipoprotein
ECDH1ME8569_RS08450	COG1566	PFAM secretion protein HlyD family protein
ECDH1ME8569_RS08455	COG1289	transmembrane transporter activity
ECDH1ME8569_RS08460	COG2032	superoxide dismutase activity
ECDH1ME8569_RS08465	COG4989	oxidoreductase activity
ECDH1ME8569_RS08470	COG3313	Fe-S protein
ECDH1ME8569_RS08475	COG1309	transcriptional regulator
ECDH1ME8569_RS08480	COG1902	pentaerythritol trinitrate reductase activity
ECDH1ME8569_RS08485	COG0346	lactoylglutathione lyase activity
ECDH1ME8569_RS08490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECDH1ME8569_RS08495	COG1201	RNA secondary structure unwinding
ECDH1ME8569_RS08500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ECDH1ME8569_RS08505	COG0791	NLP P60 protein
ECDH1ME8569_RS08510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECDH1ME8569_RS08515	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS08530	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS08535	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS08540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECDH1ME8569_RS08545	COG0307	riboflavin synthase, alpha
ECDH1ME8569_RS08560	COG3468	outer membrane autotransporter barrel domain protein
ECDH1ME8569_RS08580	COG4529	Protein conserved in bacteria
ECDH1ME8569_RS08590	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ECDH1ME8569_RS08595	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS08605	COG2414	aldehyde ferredoxin oxidoreductase
ECDH1ME8569_RS08610	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS08620	COG0469	pyruvate kinase activity
ECDH1ME8569_RS08625	COG4238	major outer membrane lipoprotein
ECDH1ME8569_RS08630	COG1376	ErfK ybiS ycfS ynhG family protein
ECDH1ME8569_RS08645	COG0719	Fe-S assembly protein
ECDH1ME8569_RS08650	COG0396	ATPase activity
ECDH1ME8569_RS08655	COG0719	Fe-S assembly protein
ECDH1ME8569_RS08660	COG0316	Belongs to the HesB IscA family
ECDH1ME8569_RS08670	COG2050	protein possibly involved in aromatic compounds catabolism
ECDH1ME8569_RS08675	COG0277	FAD linked oxidase domain protein
ECDH1ME8569_RS08675	COG0247	lactate metabolic process
ECDH1ME8569_RS08680	COG0628	permease
ECDH1ME8569_RS08690	COG0738	Major facilitator superfamily
ECDH1ME8569_RS08695	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS08710	COG4670	ketone body catabolic process
ECDH1ME8569_RS08715	COG1960	acyl-CoA dehydrogenase activity
ECDH1ME8569_RS08720	COG1917	Cupin 2, conserved barrel domain protein
ECDH1ME8569_RS08720	COG2207	Transcriptional regulator
ECDH1ME8569_RS08730	COG2086	electron transfer activity
ECDH1ME8569_RS08735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ECDH1ME8569_RS08740	COG0644	oxidoreductase
ECDH1ME8569_RS08745	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECDH1ME8569_RS08750	COG0318	PFAM AMP-dependent synthetase and ligase
ECDH1ME8569_RS08755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDH1ME8569_RS08755	COG0574	Belongs to the PEP-utilizing enzyme family
ECDH1ME8569_RS08770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECDH1ME8569_RS08775	COG4256	Hemin uptake protein
ECDH1ME8569_RS08785	COG2200	EAL domain
ECDH1ME8569_RS08790	COG0791	NLP P60 protein
ECDH1ME8569_RS08800	COG0386	Belongs to the glutathione peroxidase family
ECDH1ME8569_RS08815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECDH1ME8569_RS08815	COG0072	phenylalanine-tRNA ligase activity
ECDH1ME8569_RS08860	COG3137	Salt-induced outer membrane protein
ECDH1ME8569_RS08865	COG1105	Belongs to the carbohydrate kinase PfkB family
ECDH1ME8569_RS08875	COG3001	Fructosamine kinase
ECDH1ME8569_RS08885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECDH1ME8569_RS08890	COG1988	membrane-bound metal-dependent
ECDH1ME8569_RS08895	COG1823	symporter activity
ECDH1ME8569_RS08910	COG0753	catalase activity
ECDH1ME8569_RS08920	COG1486	melibiose metabolic process
ECDH1ME8569_RS08925	COG2169	Transcriptional regulator
ECDH1ME8569_RS08925	COG1917	Cupin 2, conserved barrel domain protein
ECDH1ME8569_RS08930	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECDH1ME8569_RS08935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECDH1ME8569_RS08940	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECDH1ME8569_RS08945	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECDH1ME8569_RS08960	COG0322	excinuclease ABC activity
ECDH1ME8569_RS08970	COG3678	ATP-independent chaperone mediated protein folding
ECDH1ME8569_RS09000	COG0708	Exodeoxyribonuclease III
ECDH1ME8569_RS09005	COG0398	Pfam SNARE associated Golgi protein
ECDH1ME8569_RS09015	COG0398	Pfam SNARE associated Golgi protein
ECDH1ME8569_RS09020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECDH1ME8569_RS09025	COG4134	Bacterial extracellular solute-binding protein
ECDH1ME8569_RS09030	COG4135	transport system, permease component
ECDH1ME8569_RS09035	COG4136	ATPase activity
ECDH1ME8569_RS09040	COG2897	thiosulfate sulfurtransferase activity
ECDH1ME8569_RS09045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECDH1ME8569_RS09050	COG0494	nUDIX hydrolase
ECDH1ME8569_RS09060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ECDH1ME8569_RS09070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECDH1ME8569_RS09085	COG0778	Nitroreductase
ECDH1ME8569_RS09095	COG0616	signal peptide processing
ECDH1ME8569_RS09100	COG0252	asparaginase activity
ECDH1ME8569_RS09105	COG1335	isochorismatase
ECDH1ME8569_RS09110	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS09115	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS09120	COG0667	Aldo Keto reductase
ECDH1ME8569_RS09125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS09130	COG0191	fructose-bisphosphate aldolase activity
ECDH1ME8569_RS09135	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS09140	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS09145	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS09150	COG3139	Protein of unknown function (DUF1315)
ECDH1ME8569_RS09160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECDH1ME8569_RS09165	COG0676	glucose-6-phosphate 1-epimerase activity
ECDH1ME8569_RS09170	COG0656	L-ascorbic acid biosynthetic process
ECDH1ME8569_RS09175	COG3713	MltA-interacting MipA family protein
ECDH1ME8569_RS09180	COG2766	serine protein kinase
ECDH1ME8569_RS09190	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS09195	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS09200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECDH1ME8569_RS09215	COG2207	Transcriptional regulator
ECDH1ME8569_RS09220	COG2807	transmembrane transport
ECDH1ME8569_RS09225	COG3189	MarR family transcriptional regulator
ECDH1ME8569_RS09230	COG3042	response to heat
ECDH1ME8569_RS09235	COG2203	Gaf domain
ECDH1ME8569_RS09235	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS09245	COG2261	transglycosylase associated protein
ECDH1ME8569_RS09255	COG3615	Tellurite resistance protein tehB
ECDH1ME8569_RS09265	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS09270	COG0473	3-isopropylmalate dehydrogenase activity
ECDH1ME8569_RS09275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECDH1ME8569_RS09280	COG4638	Rieske (2fe-2S)
ECDH1ME8569_RS09285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECDH1ME8569_RS09290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ECDH1ME8569_RS09295	COG0318	PFAM AMP-dependent synthetase and ligase
ECDH1ME8569_RS09300	COG3065	identical protein binding
ECDH1ME8569_RS09305	COG1214	PFAM Peptidase M22, glycoprotease
ECDH1ME8569_RS09310	COG1199	ATP-dependent helicase activity
ECDH1ME8569_RS09315	COG0251	oxidation-reduction process
ECDH1ME8569_RS09330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECDH1ME8569_RS09340	COG1760	l-serine dehydratase
ECDH1ME8569_RS09345	COG2200	EAL domain
ECDH1ME8569_RS09350	COG1253	flavin adenine dinucleotide binding
ECDH1ME8569_RS09360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS09360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS09365	COG3715	PTS system
ECDH1ME8569_RS09370	COG3716	PTS system mannose fructose sorbose family IID component
ECDH1ME8569_RS09390	COG2226	methyltransferase
ECDH1ME8569_RS09425	COG1414	Transcriptional regulator
ECDH1ME8569_RS09435	COG1414	Transcriptional regulator
ECDH1ME8569_RS09440	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS09450	COG0793	Belongs to the peptidase S41A family
ECDH1ME8569_RS09460	COG1956	GAF domain-containing protein
ECDH1ME8569_RS09465	COG2995	paraquat-inducible protein a
ECDH1ME8569_RS09470	COG3008	intermembrane lipid transfer
ECDH1ME8569_RS09490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECDH1ME8569_RS09505	COG1276	copper resistance
ECDH1ME8569_RS09510	COG2372	response to copper ion
ECDH1ME8569_RS09520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECDH1ME8569_RS09525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECDH1ME8569_RS09530	COG1770	oligopeptidase
ECDH1ME8569_RS09535	COG2979	Protein of unknown function (DUF533)
ECDH1ME8569_RS09550	COG3141	response to X-ray
ECDH1ME8569_RS09560	COG0800	Aldolase
ECDH1ME8569_RS09565	COG0129	dihydroxy-acid dehydratase activity
ECDH1ME8569_RS09570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ECDH1ME8569_RS09580	COG1737	Transcriptional regulator
ECDH1ME8569_RS09585	COG0469	pyruvate kinase activity
ECDH1ME8569_RS09595	COG0739	heme binding
ECDH1ME8569_RS09600	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ECDH1ME8569_RS09610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECDH1ME8569_RS09635	COG0217	transcriptional regulatory protein
ECDH1ME8569_RS09640	COG0494	nUDIX hydrolase
ECDH1ME8569_RS09650	COG1335	isochorismatase
ECDH1ME8569_RS09655	COG1801	Protein of unknown function DUF72
ECDH1ME8569_RS09660	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ECDH1ME8569_RS09675	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS09680	COG3005	denitrification pathway
ECDH1ME8569_RS09690	COG3102	Protein conserved in bacteria
ECDH1ME8569_RS09700	COG3755	Protein conserved in bacteria
ECDH1ME8569_RS09710	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECDH1ME8569_RS09715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECDH1ME8569_RS09720	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ECDH1ME8569_RS09725	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS09730	COG2201	protein-glutamate methylesterase activity
ECDH1ME8569_RS09735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ECDH1ME8569_RS09740	COG0840	transmembrane signaling receptor activity
ECDH1ME8569_RS09745	COG0840	transmembrane signaling receptor activity
ECDH1ME8569_RS09750	COG0835	chemotaxis
ECDH1ME8569_RS09755	COG2198	Histidine kinase
ECDH1ME8569_RS09755	COG0643	Histidine kinase
ECDH1ME8569_RS09760	COG1360	Flagellar Motor Protein
ECDH1ME8569_RS09765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECDH1ME8569_RS09780	COG0589	response to stress
ECDH1ME8569_RS09790	COG1877	trehalose-phosphatase activity
ECDH1ME8569_RS09795	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS09800	COG1129	ABC transporter
ECDH1ME8569_RS09805	COG1879	ABC-type sugar transport system periplasmic component
ECDH1ME8569_RS09810	COG1528	Iron-storage protein
ECDH1ME8569_RS09830	COG1528	Iron-storage protein
ECDH1ME8569_RS09840	COG0814	amino acid
ECDH1ME8569_RS09845	COG3012	SEC-C Motif Domain Protein
ECDH1ME8569_RS09845	COG3318	Belongs to the UPF0149 family
ECDH1ME8569_RS09875	COG2197	response regulator
ECDH1ME8569_RS09890	COG2197	response regulator
ECDH1ME8569_RS09895	COG1126	abc transporter atp-binding protein
ECDH1ME8569_RS09900	COG0765	amino acid transport
ECDH1ME8569_RS09910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS09920	COG1191	sigma factor activity
ECDH1ME8569_RS09925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECDH1ME8569_RS09930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECDH1ME8569_RS09935	COG1516	flagellar protein fliS
ECDH1ME8569_RS09945	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS09955	COG2391	methyltransferase activity
ECDH1ME8569_RS09960	COG0425	Belongs to the sulfur carrier protein TusA family
ECDH1ME8569_RS09965	COG2135	peptidase activity
ECDH1ME8569_RS09970	COG0454	-acetyltransferase
ECDH1ME8569_RS09995	COG1766	The M ring may be actively involved in energy transduction
ECDH1ME8569_RS10000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECDH1ME8569_RS10005	COG1317	bacterial-type flagellum organization
ECDH1ME8569_RS10010	COG1157	protein secretion by the type III secretion system
ECDH1ME8569_RS10015	COG2882	bacterial-type flagellum organization
ECDH1ME8569_RS10020	COG3144	bacterial-type flagellum assembly
ECDH1ME8569_RS10025	COG1580	Controls the rotational direction of flagella during chemotaxis
ECDH1ME8569_RS10030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECDH1ME8569_RS10035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECDH1ME8569_RS10040	COG3190	flagellar
ECDH1ME8569_RS10045	COG1338	Plays a role in the flagellum-specific transport system
ECDH1ME8569_RS10050	COG1987	bacterial-type flagellum assembly
ECDH1ME8569_RS10055	COG1684	flagellar biosynthetic protein fliR
ECDH1ME8569_RS10060	COG2197	response regulator
ECDH1ME8569_RS10080	COG3706	GGDEF domain
ECDH1ME8569_RS10085	COG5475	Uncharacterized small protein (DUF2158)
ECDH1ME8569_RS10090	COG2354	Protein conserved in bacteria
ECDH1ME8569_RS10095	COG0697	spore germination
ECDH1ME8569_RS10100	COG3727	T/G mismatch-specific endonuclease activity
ECDH1ME8569_RS10105	COG0270	DNA (cytosine-5-)-methyltransferase activity
ECDH1ME8569_RS10110	COG1418	mRNA catabolic process
ECDH1ME8569_RS10140	COG2205	protein histidine kinase activity
ECDH1ME8569_RS10145	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS10150	COG2351	hydroxyisourate hydrolase activity
ECDH1ME8569_RS10165	COG3443	Belongs to the bacterial solute-binding protein 9 family
ECDH1ME8569_RS10170	COG3038	cytochrome b561
ECDH1ME8569_RS10195	COG1470	cell adhesion involved in biofilm formation
ECDH1ME8569_RS10195	COG1388	LysM domain
ECDH1ME8569_RS10205	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS10210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ECDH1ME8569_RS10215	COG0217	transcriptional regulatory protein
ECDH1ME8569_RS10225	COG0534	Mate efflux family protein
ECDH1ME8569_RS10235	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS10240	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS10250	COG1376	ErfK ybiS ycfS ynhG family protein
ECDH1ME8569_RS10265	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ECDH1ME8569_RS10275	COG3039	Transposase
ECDH1ME8569_RS10295	COG4771	TonB-dependent receptor
ECDH1ME8569_RS10305	COG3468	outer membrane autotransporter barrel domain protein
ECDH1ME8569_RS10315	COG2003	Belongs to the UPF0758 family
ECDH1ME8569_RS10355	COG1289	transmembrane transporter activity
ECDH1ME8569_RS10365	COG1686	Belongs to the peptidase S11 family
ECDH1ME8569_RS10370	COG2925	Exonuclease
ECDH1ME8569_RS10375	COG0425	Belongs to the sulfur carrier protein TusA family
ECDH1ME8569_RS10380	COG2391	methyltransferase activity
ECDH1ME8569_RS10385	COG0531	amino acid
ECDH1ME8569_RS10390	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS10395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECDH1ME8569_RS10400	COG4115	mRNA cleavage
ECDH1ME8569_RS10405	COG2161	toxin-antitoxin pair type II binding
ECDH1ME8569_RS10415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ECDH1ME8569_RS10425	COG0131	Imidazoleglycerol-phosphate dehydratase
ECDH1ME8569_RS10425	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECDH1ME8569_RS10430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ECDH1ME8569_RS10445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ECDH1ME8569_RS10445	COG0140	phosphoribosyl-ATP diphosphatase activity
ECDH1ME8569_RS10450	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECDH1ME8569_RS10455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ECDH1ME8569_RS10460	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ECDH1ME8569_RS10475	COG0438	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS10480	COG0110	maltose O-acetyltransferase activity
ECDH1ME8569_RS10485	COG0438	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS10495	COG0562	UDP-galactopyranose mutase
ECDH1ME8569_RS10500	COG2244	polysaccharide biosynthetic process
ECDH1ME8569_RS10505	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ECDH1ME8569_RS10510	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ECDH1ME8569_RS10520	COG1088	dTDP-glucose 4,6-dehydratase activity
ECDH1ME8569_RS10525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ECDH1ME8569_RS10535	COG0438	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS10540	COG2327	Polysaccharide pyruvyl transferase
ECDH1ME8569_RS10545	COG2244	polysaccharide biosynthetic process
ECDH1ME8569_RS10550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ECDH1ME8569_RS10555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECDH1ME8569_RS10560	COG0662	Cupin 2, conserved barrel domain protein
ECDH1ME8569_RS10560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ECDH1ME8569_RS10565	COG0297	glycogen (starch) synthase activity
ECDH1ME8569_RS10570	COG1051	belongs to the nudix hydrolase family
ECDH1ME8569_RS10575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECDH1ME8569_RS10580	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ECDH1ME8569_RS10585	COG0110	maltose O-acetyltransferase activity
ECDH1ME8569_RS10590	COG1216	Glycosyl transferase, family 2
ECDH1ME8569_RS10600	COG0438	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS10605	COG1045	serine acetyltransferase
ECDH1ME8569_RS10610	COG0463	Glycosyl transferase, family 2
ECDH1ME8569_RS10615	COG3206	protein involved in exopolysaccharide biosynthesis
ECDH1ME8569_RS10615	COG0489	protein tyrosine kinase activity
ECDH1ME8569_RS10620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECDH1ME8569_RS10625	COG1596	polysaccharide export
ECDH1ME8569_RS10630	COG1253	flavin adenine dinucleotide binding
ECDH1ME8569_RS10635	COG2982	Protein involved in outer membrane biogenesis
ECDH1ME8569_RS10645	COG0572	uridine kinase
ECDH1ME8569_RS10650	COG3447	MASE1 domain protein
ECDH1ME8569_RS10650	COG5001	Diguanylate cyclase
ECDH1ME8569_RS10650	COG5002	protein histidine kinase activity
ECDH1ME8569_RS10655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ECDH1ME8569_RS10665	COG0443	Heat shock 70 kDa protein
ECDH1ME8569_RS10670	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ECDH1ME8569_RS10675	COG3779	Protein conserved in bacteria
ECDH1ME8569_RS10680	COG0631	protein serine/threonine phosphatase activity
ECDH1ME8569_RS10685	COG4245	von Willebrand factor, type A
ECDH1ME8569_RS10710	COG2205	protein histidine kinase activity
ECDH1ME8569_RS10715	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS10720	COG3422	double-strand break repair
ECDH1ME8569_RS10725	COG0826	peptidase U32
ECDH1ME8569_RS10760	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS10770	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS10775	COG3775	system Galactitol-specific IIC component
ECDH1ME8569_RS10785	COG3414	Phosphotransferase system galactitol-specific IIB component
ECDH1ME8569_RS10790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS10805	COG1830	Aldolase
ECDH1ME8569_RS10810	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS10815	COG1397	ADP-ribosylglycohydrolase
ECDH1ME8569_RS10820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS10825	COG2188	Transcriptional regulator
ECDH1ME8569_RS10830	COG3757	hydrolase, family 25
ECDH1ME8569_RS10835	COG0351	phosphomethylpyrimidine kinase
ECDH1ME8569_RS10850	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ECDH1ME8569_RS10855	COG5455	response to cobalt ion
ECDH1ME8569_RS10860	COG3539	Fimbrial protein
ECDH1ME8569_RS10865	COG3188	usher protein
ECDH1ME8569_RS10870	COG3121	Chaperone
ECDH1ME8569_RS10875	COG3539	Fimbrial protein
ECDH1ME8569_RS10890	COG0489	protein tyrosine kinase activity
ECDH1ME8569_RS10910	COG3831	ATPase activity
ECDH1ME8569_RS10920	COG0714	Associated with various cellular activities
ECDH1ME8569_RS10925	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ECDH1ME8569_RS10930	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ECDH1ME8569_RS10935	COG4715	Zinc finger, swim domain protein
ECDH1ME8569_RS10940	COG4808	Protein conserved in bacteria
ECDH1ME8569_RS10945	COG4807	Protein conserved in bacteria
ECDH1ME8569_RS10950	COG3279	Response regulator of the LytR AlgR family
ECDH1ME8569_RS10955	COG3275	phosphorelay sensor kinase activity
ECDH1ME8569_RS10960	COG0789	Transcriptional regulator
ECDH1ME8569_RS10970	COG1174	glycine betaine transport
ECDH1ME8569_RS10975	COG1125	glycine betaine transport
ECDH1ME8569_RS10980	COG1174	glycine betaine transport
ECDH1ME8569_RS10985	COG1732	Glycine betaine
ECDH1ME8569_RS10990	COG1472	Belongs to the glycosyl hydrolase 3 family
ECDH1ME8569_RS10995	COG0277	FAD linked oxidase domain protein
ECDH1ME8569_RS11000	COG1686	Belongs to the peptidase S11 family
ECDH1ME8569_RS11010	COG0586	Pfam SNARE associated Golgi protein
ECDH1ME8569_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS11030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECDH1ME8569_RS11040	COG1346	cytolysis
ECDH1ME8569_RS11050	COG2949	membrane
ECDH1ME8569_RS11060	COG0493	'glutamate synthase
ECDH1ME8569_RS11065	COG0167	dihydroorotate dehydrogenase activity
ECDH1ME8569_RS11065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ECDH1ME8569_RS11070	COG4211	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS11075	COG1129	ABC transporter
ECDH1ME8569_RS11080	COG1879	ABC-type sugar transport system periplasmic component
ECDH1ME8569_RS11085	COG1609	Transcriptional regulator
ECDH1ME8569_RS11095	COG2311	Membrane
ECDH1ME8569_RS11115	COG4771	TonB-dependent receptor
ECDH1ME8569_RS11120	COG0833	amino acid
ECDH1ME8569_RS11125	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS11130	COG2855	membrane
ECDH1ME8569_RS11140	COG1522	sequence-specific DNA binding
ECDH1ME8569_RS11140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS11145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECDH1ME8569_RS11155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECDH1ME8569_RS11160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECDH1ME8569_RS11165	COG2313	pseudouridylate synthase activity
ECDH1ME8569_RS11170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS11175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS11175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ECDH1ME8569_RS11175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS11180	COG1105	Belongs to the carbohydrate kinase PfkB family
ECDH1ME8569_RS11185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS11185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS11190	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS11205	COG0246	Mannitol dehydrogenase
ECDH1ME8569_RS11210	COG0523	cobalamin synthesis protein
ECDH1ME8569_RS11215	COG0671	phosphoesterase, PA-phosphatase related
ECDH1ME8569_RS11220	COG0791	NLP P60 protein
ECDH1ME8569_RS11225	COG2200	EAL domain
ECDH1ME8569_RS11230	COG4166	transmembrane transport
ECDH1ME8569_RS11235	COG4174	ABC transporter (Permease)
ECDH1ME8569_RS11240	COG4239	(ABC) transporter, permease
ECDH1ME8569_RS11245	COG4172	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS11255	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS11260	COG1187	pseudouridine synthase activity
ECDH1ME8569_RS11265	COG1061	Type III restriction enzyme res subunit
ECDH1ME8569_RS11285	COG3083	sulfuric ester hydrolase activity
ECDH1ME8569_RS11295	COG3468	outer membrane autotransporter barrel domain protein
ECDH1ME8569_RS11310	COG2197	response regulator
ECDH1ME8569_RS11315	COG4235	cytochrome complex assembly
ECDH1ME8569_RS11315	COG3088	subunit of a heme lyase
ECDH1ME8569_RS11320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECDH1ME8569_RS11325	COG1138	Cytochrome C-type biogenesis protein
ECDH1ME8569_RS11335	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECDH1ME8569_RS11340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECDH1ME8569_RS11345	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECDH1ME8569_RS11350	COG4133	protoheme IX ABC transporter activity
ECDH1ME8569_RS11355	COG3005	denitrification pathway
ECDH1ME8569_RS11360	COG3043	anaerobic respiration
ECDH1ME8569_RS11365	COG0348	domain, Protein
ECDH1ME8569_RS11370	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS11380	COG3062	negative regulation of establishment of protein localization
ECDH1ME8569_RS11385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS11385	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS11405	COG4615	Cyclic peptide transporter
ECDH1ME8569_RS11410	COG3145	DNA-N1-methyladenine dioxygenase activity
ECDH1ME8569_RS11415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECDH1ME8569_RS11415	COG2169	Transcriptional regulator
ECDH1ME8569_RS11420	COG1477	protein flavinylation
ECDH1ME8569_RS11425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECDH1ME8569_RS11440	COG0642	Histidine kinase
ECDH1ME8569_RS11440	COG2198	Histidine kinase
ECDH1ME8569_RS11445	COG2197	response regulator
ECDH1ME8569_RS11450	COG2205	protein histidine kinase activity
ECDH1ME8569_RS11450	COG0784	Response regulator, receiver
ECDH1ME8569_RS11455	COG3852	Histidine kinase
ECDH1ME8569_RS11460	COG2204	response regulator
ECDH1ME8569_RS11465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ECDH1ME8569_RS11470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ECDH1ME8569_RS11475	COG2031	fatty acid transporter
ECDH1ME8569_RS11480	COG0183	Belongs to the thiolase family
ECDH1ME8569_RS11485	COG4676	Protein conserved in bacteria
ECDH1ME8569_RS11490	COG5445	Predicted secreted protein (DUF2300)
ECDH1ME8569_RS11495	COG2373	Large extracellular alpha-helical protein
ECDH1ME8569_RS11505	COG3234	Protein of unknown function (DUF1175)
ECDH1ME8569_RS11510	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ECDH1ME8569_RS11515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECDH1ME8569_RS11525	COG3468	outer membrane autotransporter barrel domain protein
ECDH1ME8569_RS11535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECDH1ME8569_RS11540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECDH1ME8569_RS11545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECDH1ME8569_RS11550	COG3642	lipopolysaccharide core region biosynthetic process
ECDH1ME8569_RS11555	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS11560	COG0584	glycerophosphoryl diester phosphodiesterase
ECDH1ME8569_RS11565	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS11570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECDH1ME8569_RS11580	COG0247	lactate metabolic process
ECDH1ME8569_RS11585	COG5464	transposase or invertase
ECDH1ME8569_RS11600	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS11610	COG1414	Transcriptional regulator
ECDH1ME8569_RS11675	COG0318	PFAM AMP-dependent synthetase and ligase
ECDH1ME8569_RS11685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ECDH1ME8569_RS11700	COG1169	isochorismate synthase
ECDH1ME8569_RS11705	COG4575	ribosome binding
ECDH1ME8569_RS11710	COG2153	protein acetylation
ECDH1ME8569_RS11720	COG5160	protein modification by small protein removal
ECDH1ME8569_RS11725	COG2304	oxidoreductase activity
ECDH1ME8569_RS11730	COG2234	aminopeptidase activity
ECDH1ME8569_RS11750	COG0457	Tetratricopeptide repeat
ECDH1ME8569_RS11760	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECDH1ME8569_RS11765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECDH1ME8569_RS11775	COG0839	Belongs to the complex I subunit 6 family
ECDH1ME8569_RS11790	COG1034	ATP synthesis coupled electron transport
ECDH1ME8569_RS11795	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ECDH1ME8569_RS11800	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ECDH1ME8569_RS11820	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS11825	COG0436	Aminotransferase
ECDH1ME8569_RS11835	COG0490	domain, Protein
ECDH1ME8569_RS11835	COG0471	metal ion transport
ECDH1ME8569_RS11840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECDH1ME8569_RS11860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECDH1ME8569_RS11865	COG0857	belongs to the CobB CobQ family
ECDH1ME8569_RS11865	COG0280	phosphate acetyltransferase
ECDH1ME8569_RS11870	COG1288	antiporter activity
ECDH1ME8569_RS11875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ECDH1ME8569_RS11880	COG0622	Phosphoesterase
ECDH1ME8569_RS11885	COG0625	glutathione transferase activity
ECDH1ME8569_RS11890	COG0625	glutathione transferase activity
ECDH1ME8569_RS11895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECDH1ME8569_RS11900	COG1090	epimerase
ECDH1ME8569_RS11905	COG5464	transposase or invertase
ECDH1ME8569_RS11910	COG4598	ABC transporter
ECDH1ME8569_RS11915	COG4160	amino acid transport
ECDH1ME8569_RS11920	COG4215	(ABC) transporter
ECDH1ME8569_RS11925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS11935	COG0163	prenyltransferase activity
ECDH1ME8569_RS11940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ECDH1ME8569_RS11945	COG1286	toxin biosynthetic process
ECDH1ME8569_RS11950	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ECDH1ME8569_RS11955	COG0285	dihydrofolate synthase activity
ECDH1ME8569_RS11965	COG0586	Pfam SNARE associated Golgi protein
ECDH1ME8569_RS11975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECDH1ME8569_RS11990	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS11995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECDH1ME8569_RS12010	COG3101	peptidyl-lysine hydroxylation
ECDH1ME8569_RS12015	COG0730	response to heat
ECDH1ME8569_RS12030	COG2890	protein-(glutamine-N5) methyltransferase activity
ECDH1ME8569_RS12045	COG3539	Fimbrial protein
ECDH1ME8569_RS12050	COG3539	Fimbrial protein
ECDH1ME8569_RS12055	COG3539	Fimbrial protein
ECDH1ME8569_RS12060	COG3121	Chaperone
ECDH1ME8569_RS12070	COG3539	Fimbrial protein
ECDH1ME8569_RS12075	COG2062	phosphohistidine phosphatase, SixA
ECDH1ME8569_RS12090	COG3691	Protein conserved in bacteria
ECDH1ME8569_RS12095	COG2067	long-chain fatty acid transport protein
ECDH1ME8569_RS12105	COG2853	Lipoprotein
ECDH1ME8569_RS12110	COG2116	formate transmembrane transporter activity
ECDH1ME8569_RS12120	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS12125	COG2246	polysaccharide biosynthetic process
ECDH1ME8569_RS12130	COG0463	Glycosyl transferase, family 2
ECDH1ME8569_RS12155	COG4725	Belongs to the MT-A70-like family
ECDH1ME8569_RS12165	COG1846	Transcriptional regulator
ECDH1ME8569_RS12175	COG5532	Uncharacterized conserved protein (DUF2303)
ECDH1ME8569_RS12180	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ECDH1ME8569_RS12200	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS12205	COG2610	gluconate transmembrane transporter activity
ECDH1ME8569_RS12215	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS12220	COG1566	PFAM secretion protein HlyD family protein
ECDH1ME8569_RS12225	COG2197	response regulator
ECDH1ME8569_RS12230	COG2205	protein histidine kinase activity
ECDH1ME8569_RS12230	COG2198	Histidine kinase
ECDH1ME8569_RS12230	COG0784	Response regulator, receiver
ECDH1ME8569_RS12230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS12235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ECDH1ME8569_RS12240	COG0679	Auxin Efflux Carrier
ECDH1ME8569_RS12245	COG0028	Belongs to the TPP enzyme family
ECDH1ME8569_RS12275	COG1560	Kdo2-lipid A biosynthetic process
ECDH1ME8569_RS12280	COG0436	Aminotransferase
ECDH1ME8569_RS12285	COG3275	phosphorelay sensor kinase activity
ECDH1ME8569_RS12290	COG3279	Response regulator of the LytR AlgR family
ECDH1ME8569_RS12295	COG2207	Transcriptional regulator
ECDH1ME8569_RS12300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS12300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS12300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDH1ME8569_RS12305	COG1363	Peptidase, m42
ECDH1ME8569_RS12310	COG0006	proline dipeptidase activity
ECDH1ME8569_RS12315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS12320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS12350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECDH1ME8569_RS12355	COG3385	transposase activity
ECDH1ME8569_RS12360	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS12360	COG2200	EAL domain
ECDH1ME8569_RS12375	COG3415	Transposase
ECDH1ME8569_RS12380	COG3415	Transposase
ECDH1ME8569_RS12410	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS12420	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS12425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ECDH1ME8569_RS12435	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS12440	COG0385	Bile acid
ECDH1ME8569_RS12445	COG3530	Putative quorum-sensing-regulated virulence factor
ECDH1ME8569_RS12465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECDH1ME8569_RS12470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS12475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDH1ME8569_RS12480	COG2190	(PTS) system
ECDH1ME8569_RS12495	COG4884	unkown
ECDH1ME8569_RS12495	COG3831	ATPase activity
ECDH1ME8569_RS12500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECDH1ME8569_RS12505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ECDH1ME8569_RS12510	COG4208	sulfate ABC transporter
ECDH1ME8569_RS12515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ECDH1ME8569_RS12520	COG4150	thiosulfate binding
ECDH1ME8569_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS12540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS12540	COG1263	PTS System
ECDH1ME8569_RS12545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECDH1ME8569_RS12550	COG2837	iron assimilation
ECDH1ME8569_RS12565	COG0456	acetyltransferase
ECDH1ME8569_RS12570	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECDH1ME8569_RS12580	COG2207	Transcriptional regulator
ECDH1ME8569_RS12585	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECDH1ME8569_RS12590	COG4816	utilization protein
ECDH1ME8569_RS12600	COG4303	Ethanolamine ammonia lyase large subunit
ECDH1ME8569_RS12605	COG4819	ethanolamine utilization protein
ECDH1ME8569_RS12610	COG3192	ethanolamine utilization protein
ECDH1ME8569_RS12615	COG1454	alcohol dehydrogenase
ECDH1ME8569_RS12620	COG4820	ethanolamine utilization protein (EutJ)
ECDH1ME8569_RS12625	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS12630	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ECDH1ME8569_RS12635	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECDH1ME8569_RS12640	COG0280	phosphate acetyltransferase
ECDH1ME8569_RS12645	COG4812	Cobalamin adenosyltransferase
ECDH1ME8569_RS12650	COG4766	ethanolamine catabolic process
ECDH1ME8569_RS12655	COG4917	ethanolamine utilization protein
ECDH1ME8569_RS12660	COG4810	utilization protein
ECDH1ME8569_RS12665	COG0280	phosphate acetyltransferase
ECDH1ME8569_RS12665	COG0281	malic enzyme
ECDH1ME8569_RS12670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECDH1ME8569_RS12675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECDH1ME8569_RS12680	COG5342	invasion associated locus B
ECDH1ME8569_RS12690	COG0493	'glutamate synthase
ECDH1ME8569_RS12690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS12695	COG3850	Histidine kinase
ECDH1ME8569_RS12700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECDH1ME8569_RS12710	COG1393	Belongs to the ArsC family
ECDH1ME8569_RS12725	COG0400	carboxylic ester hydrolase activity
ECDH1ME8569_RS12730	COG1444	tRNA N-acetyltransferase activity
ECDH1ME8569_RS12735	COG2321	neutral zinc metallopeptidase
ECDH1ME8569_RS12750	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ECDH1ME8569_RS12760	COG2716	regulation of RNA biosynthetic process
ECDH1ME8569_RS12765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ECDH1ME8569_RS12770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS12775	COG0651	ATP synthesis coupled electron transport
ECDH1ME8569_RS12780	COG0650	Formate hydrogenlyase subunit 4
ECDH1ME8569_RS12785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECDH1ME8569_RS12790	COG4237	Hydrogenase 4 membrane
ECDH1ME8569_RS12795	COG0651	ATP synthesis coupled electron transport
ECDH1ME8569_RS12800	COG3261	NADH dehydrogenase
ECDH1ME8569_RS12800	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECDH1ME8569_RS12805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECDH1ME8569_RS12810	COG3260	NADH ubiquinone oxidoreductase 20
ECDH1ME8569_RS12820	COG3604	Transcriptional regulator
ECDH1ME8569_RS12825	COG2116	formate transmembrane transporter activity
ECDH1ME8569_RS12830	COG0628	permease
ECDH1ME8569_RS12835	COG4783	chaperone-mediated protein folding
ECDH1ME8569_RS12840	COG1393	Belongs to the ArsC family
ECDH1ME8569_RS12850	COG2233	PERMEase
ECDH1ME8569_RS12865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ECDH1ME8569_RS12870	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ECDH1ME8569_RS12875	COG0248	Ppx GppA phosphatase
ECDH1ME8569_RS12880	COG2200	EAL domain
ECDH1ME8569_RS12895	COG3133	Outer membrane lipoprotein
ECDH1ME8569_RS12910	COG0516	GMP reductase activity
ECDH1ME8569_RS12910	COG0517	IMP dehydrogenase activity
ECDH1ME8569_RS12920	COG1645	bacterial-type flagellum-dependent swarming motility
ECDH1ME8569_RS12930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECDH1ME8569_RS12935	COG2976	Protein conserved in bacteria
ECDH1ME8569_RS12965	COG4953	penicillin-binding protein 1C
ECDH1ME8569_RS12970	COG2373	Large extracellular alpha-helical protein
ECDH1ME8569_RS12975	COG2897	thiosulfate sulfurtransferase activity
ECDH1ME8569_RS12990	COG2975	iron-sulfur cluster assembly
ECDH1ME8569_RS12995	COG0633	Ferredoxin
ECDH1ME8569_RS13015	COG0822	iron-sulfur transferase activity
ECDH1ME8569_RS13035	COG0483	inositol monophosphate 1-phosphatase activity
ECDH1ME8569_RS13040	COG1073	alpha beta
ECDH1ME8569_RS13045	COG3711	transcriptional antiterminator
ECDH1ME8569_RS13050	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS13055	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS13060	COG4638	Rieske (2fe-2S)
ECDH1ME8569_RS13085	COG2259	Doxx family
ECDH1ME8569_RS13090	COG2017	converts alpha-aldose to the beta-anomer
ECDH1ME8569_RS13095	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS13100	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS13105	COG1129	ABC transporter
ECDH1ME8569_RS13110	COG1879	ABC-type sugar transport system periplasmic component
ECDH1ME8569_RS13115	COG0457	Tetratricopeptide repeat
ECDH1ME8569_RS13120	COG1940	carbohydrate kinase activity
ECDH1ME8569_RS13130	COG1017	nitric oxide dioxygenase activity
ECDH1ME8569_RS13130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECDH1ME8569_RS13135	COG0347	Belongs to the P(II) protein family
ECDH1ME8569_RS13140	COG2204	response regulator
ECDH1ME8569_RS13145	COG3170	Tfp pilus assembly protein FimV
ECDH1ME8569_RS13150	COG2205	protein histidine kinase activity
ECDH1ME8569_RS13155	COG0047	phosphoribosylformylglycinamidine synthase activity
ECDH1ME8569_RS13155	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ECDH1ME8569_RS13170	COG0560	Phosphoserine phosphatase
ECDH1ME8569_RS13175	COG1737	Transcriptional regulator
ECDH1ME8569_RS13180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS13205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ECDH1ME8569_RS13225	COG0681	Belongs to the peptidase S26 family
ECDH1ME8569_RS13235	COG3086	response to oxidative stress
ECDH1ME8569_RS13240	COG3026	antisigma factor binding
ECDH1ME8569_RS13245	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ECDH1ME8569_RS13250	COG1595	DNA-templated transcription, initiation
ECDH1ME8569_RS13260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECDH1ME8569_RS13270	COG0513	Belongs to the DEAD box helicase family
ECDH1ME8569_RS13280	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS13300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECDH1ME8569_RS13310	COG3118	belongs to the thioredoxin family
ECDH1ME8569_RS13315	COG3148	PFAM DTW domain containing protein
ECDH1ME8569_RS13320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECDH1ME8569_RS13320	COG0045	succinate-CoA ligase (ADP-forming) activity
ECDH1ME8569_RS13320	COG1042	CoA-binding domain protein
ECDH1ME8569_RS13325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECDH1ME8569_RS13330	COG5544	Lipoprotein
ECDH1ME8569_RS13335	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS13365	COG0542	response to heat
ECDH1ME8569_RS13370	COG1496	oxidoreductase activity
ECDH1ME8569_RS13375	COG0564	pseudouridine synthase activity
ECDH1ME8569_RS13380	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECDH1ME8569_RS13390	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECDH1ME8569_RS13395	COG1605	Chorismate mutase
ECDH1ME8569_RS13395	COG0077	Prephenate dehydratase
ECDH1ME8569_RS13400	COG1605	Chorismate mutase
ECDH1ME8569_RS13400	COG0287	Prephenate dehydrogenase
ECDH1ME8569_RS13405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECDH1ME8569_RS13420	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS13425	COG2885	chlorophyll binding
ECDH1ME8569_RS13450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECDH1ME8569_RS13455	COG4137	Cytochrome C assembly protein
ECDH1ME8569_RS13460	COG4536	flavin adenine dinucleotide binding
ECDH1ME8569_RS13480	COG0497	DNA recombination
ECDH1ME8569_RS13485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECDH1ME8569_RS13495	COG2867	negative regulation of translational initiation
ECDH1ME8569_RS13505	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS13515	COG3311	Transcriptional regulator
ECDH1ME8569_RS13520	COG4983	Phage plasmid primase, P4 family domain protein
ECDH1ME8569_RS13530	COG1204	response to ionizing radiation
ECDH1ME8569_RS13540	COG1479	Protein of unknown function DUF262
ECDH1ME8569_RS13555	COG3596	GTP binding
ECDH1ME8569_RS13565	COG2378	regulation of single-species biofilm formation
ECDH1ME8569_RS13605	COG2003	Belongs to the UPF0758 family
ECDH1ME8569_RS13620	COG3468	outer membrane autotransporter barrel domain protein
ECDH1ME8569_RS13655	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS13660	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS13665	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS13675	COG0579	oxidoreductase
ECDH1ME8569_RS13680	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS13685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECDH1ME8569_RS13690	COG1113	amino acid transport
ECDH1ME8569_RS13695	COG1802	Transcriptional regulator
ECDH1ME8569_RS13700	COG1652	LysM domain
ECDH1ME8569_RS13705	COG0401	homolog of Blt101
ECDH1ME8569_RS13710	COG0640	Transcriptional regulator
ECDH1ME8569_RS13715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECDH1ME8569_RS13720	COG2916	Histone family protein nucleoid-structuring protein H-NS
ECDH1ME8569_RS13735	COG4575	ribosome binding
ECDH1ME8569_RS13740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECDH1ME8569_RS13750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECDH1ME8569_RS13755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECDH1ME8569_RS13760	COG4175	Glycine betaine
ECDH1ME8569_RS13765	COG4176	ABC-type proline glycine betaine transport system permease component
ECDH1ME8569_RS13770	COG2113	Glycine betaine
ECDH1ME8569_RS13780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ECDH1ME8569_RS13790	COG1846	Transcriptional regulator
ECDH1ME8569_RS13795	COG1566	PFAM secretion protein HlyD family protein
ECDH1ME8569_RS13800	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS13815	COG1238	metal cluster binding
ECDH1ME8569_RS13820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECDH1ME8569_RS13855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ECDH1ME8569_RS13880	COG1546	Belongs to the CinA family
ECDH1ME8569_RS13885	COG2951	lytic endotransglycosylase activity
ECDH1ME8569_RS13890	COG3730	PTS system glucitol sorbitol-specific
ECDH1ME8569_RS13895	COG3732	PTS system glucitol sorbitol-specific
ECDH1ME8569_RS13900	COG3731	PTS system glucitol sorbitol-specific IIA component
ECDH1ME8569_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS13910	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS13915	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS13920	COG0517	IMP dehydrogenase activity
ECDH1ME8569_RS13920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECDH1ME8569_RS13940	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ECDH1ME8569_RS13945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS13950	COG1609	Transcriptional regulator
ECDH1ME8569_RS13955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS13955	COG1263	PTS System
ECDH1ME8569_RS13960	COG2723	6-phospho-beta-galactosidase activity
ECDH1ME8569_RS13965	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECDH1ME8569_RS13975	COG3260	NADH ubiquinone oxidoreductase 20
ECDH1ME8569_RS13980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECDH1ME8569_RS13985	COG3261	NADH dehydrogenase
ECDH1ME8569_RS13985	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECDH1ME8569_RS13990	COG0650	Formate hydrogenlyase subunit 4
ECDH1ME8569_RS13995	COG0651	ATP synthesis coupled electron transport
ECDH1ME8569_RS14000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS14015	COG0375	protein maturation
ECDH1ME8569_RS14020	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ECDH1ME8569_RS14025	COG0298	carbon dioxide binding
ECDH1ME8569_RS14030	COG0409	Hydrogenase expression formation protein
ECDH1ME8569_RS14035	COG0309	Hydrogenase expression formation protein (HypE)
ECDH1ME8569_RS14040	COG3604	Transcriptional regulator
ECDH1ME8569_RS14055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECDH1ME8569_RS14060	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS14065	COG2084	Dehydrogenase
ECDH1ME8569_RS14070	COG3395	kinase activity
ECDH1ME8569_RS14075	COG0235	Class ii aldolase
ECDH1ME8569_RS14080	COG3622	Belongs to the hyi family
ECDH1ME8569_RS14085	COG2610	gluconate transmembrane transporter activity
ECDH1ME8569_RS14090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECDH1ME8569_RS14095	COG4942	peptidase
ECDH1ME8569_RS14095	COG1388	LysM domain
ECDH1ME8569_RS14150	COG2234	aminopeptidase activity
ECDH1ME8569_RS14155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECDH1ME8569_RS14160	COG1518	maintenance of DNA repeat elements
ECDH1ME8569_RS14175	COG1857	crispr-associated protein
ECDH1ME8569_RS14190	COG1203	CRISPR-associated helicase, Cas3
ECDH1ME8569_RS14205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ECDH1ME8569_RS14210	COG0720	synthase
ECDH1ME8569_RS14215	COG0644	oxidoreductase
ECDH1ME8569_RS14220	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECDH1ME8569_RS14225	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ECDH1ME8569_RS14230	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ECDH1ME8569_RS14235	COG2086	electron transfer activity
ECDH1ME8569_RS14240	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS14245	COG0277	FAD linked oxidase domain protein
ECDH1ME8569_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS14255	COG2223	nitrite transmembrane transporter activity
ECDH1ME8569_RS14260	COG1070	Carbohydrate kinase
ECDH1ME8569_RS14265	COG0602	queuosine metabolic process
ECDH1ME8569_RS14275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECDH1ME8569_RS14290	COG3956	TIGRFAM MazG family protein
ECDH1ME8569_RS14295	COG2337	Toxic component of a toxin-antitoxin (TA) module
ECDH1ME8569_RS14300	COG2336	PFAM SpoVT AbrB
ECDH1ME8569_RS14305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECDH1ME8569_RS14310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECDH1ME8569_RS14315	COG2205	protein histidine kinase activity
ECDH1ME8569_RS14315	COG3437	response regulator, receiver
ECDH1ME8569_RS14315	COG3850	Histidine kinase
ECDH1ME8569_RS14315	COG4999	Histidine kinase
ECDH1ME8569_RS14320	COG4948	Mandelate Racemase Muconate Lactonizing
ECDH1ME8569_RS14325	COG4948	Mandelate Racemase Muconate Lactonizing
ECDH1ME8569_RS14330	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS14335	COG0716	FMN binding
ECDH1ME8569_RS14340	COG0564	pseudouridine synthase activity
ECDH1ME8569_RS14345	COG3098	single-species biofilm formation
ECDH1ME8569_RS14365	COG1611	Belongs to the LOG family
ECDH1ME8569_RS14370	COG0814	amino acid
ECDH1ME8569_RS14375	COG1760	l-serine dehydratase
ECDH1ME8569_RS14385	COG1454	alcohol dehydrogenase
ECDH1ME8569_RS14390	COG0235	Class ii aldolase
ECDH1ME8569_RS14395	COG0738	Major facilitator superfamily
ECDH1ME8569_RS14405	COG1070	Carbohydrate kinase
ECDH1ME8569_RS14415	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS14425	COG2363	Small membrane protein
ECDH1ME8569_RS14430	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS14440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECDH1ME8569_RS14445	COG2166	iron-sulfur cluster assembly
ECDH1ME8569_RS14450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ECDH1ME8569_RS14455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ECDH1ME8569_RS14475	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECDH1ME8569_RS14480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ECDH1ME8569_RS14480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ECDH1ME8569_RS14485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ECDH1ME8569_RS14490	COG1074	ATP-dependent DNA helicase activity
ECDH1ME8569_RS14495	COG1025	Belongs to the peptidase M16 family
ECDH1ME8569_RS14500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ECDH1ME8569_RS14505	COG4967	type IV pilus modification protein PilV
ECDH1ME8569_RS14515	COG4795	General secretion pathway protein
ECDH1ME8569_RS14520	COG2165	general secretion pathway protein
ECDH1ME8569_RS14535	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ECDH1ME8569_RS14560	COG0861	Integral membrane protein TerC family
ECDH1ME8569_RS14570	COG0667	Aldo Keto reductase
ECDH1ME8569_RS14585	COG1609	Transcriptional regulator
ECDH1ME8569_RS14595	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS14600	COG1794	racemase activity, acting on amino acids and derivatives
ECDH1ME8569_RS14605	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS14610	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS14620	COG0183	Belongs to the thiolase family
ECDH1ME8569_RS14625	COG0814	amino acid
ECDH1ME8569_RS14630	COG2771	luxR family
ECDH1ME8569_RS14635	COG3710	Transcriptional regulator
ECDH1ME8569_RS14655	COG0457	Tetratricopeptide repeat
ECDH1ME8569_RS14660	COG0457	Tetratricopeptide repeat
ECDH1ME8569_RS14660	COG3710	Transcriptional regulator
ECDH1ME8569_RS14675	COG2197	response regulator
ECDH1ME8569_RS14680	COG2197	response regulator
ECDH1ME8569_RS14710	COG3387	PFAM Glycoside hydrolase 15-related
ECDH1ME8569_RS14715	COG3387	PFAM Glycoside hydrolase 15-related
ECDH1ME8569_RS14725	COG4942	peptidase
ECDH1ME8569_RS14730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECDH1ME8569_RS14735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECDH1ME8569_RS14740	COG2080	2 iron, 2 sulfur cluster binding
ECDH1ME8569_RS14745	COG3829	transcription factor binding
ECDH1ME8569_RS14750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECDH1ME8569_RS14755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECDH1ME8569_RS14760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECDH1ME8569_RS14770	COG0549	Belongs to the carbamate kinase family
ECDH1ME8569_RS14775	COG3608	succinylglutamate desuccinylase aspartoacylase
ECDH1ME8569_RS14775	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ECDH1ME8569_RS14780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECDH1ME8569_RS14785	COG2068	MobA-Related Protein
ECDH1ME8569_RS14790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS14790	COG0493	'glutamate synthase
ECDH1ME8569_RS14795	COG0402	S-adenosylhomocysteine deaminase activity
ECDH1ME8569_RS14800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECDH1ME8569_RS14805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECDH1ME8569_RS14805	COG2080	2 iron, 2 sulfur cluster binding
ECDH1ME8569_RS14810	COG2233	PERMEase
ECDH1ME8569_RS14815	COG0402	S-adenosylhomocysteine deaminase activity
ECDH1ME8569_RS14820	COG2252	PERMEase
ECDH1ME8569_RS14825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS14830	COG0493	'glutamate synthase
ECDH1ME8569_RS14830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS14840	COG2233	PERMEase
ECDH1ME8569_RS14855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECDH1ME8569_RS14865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ECDH1ME8569_RS14870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECDH1ME8569_RS14875	COG4974	Belongs to the 'phage' integrase family
ECDH1ME8569_RS14880	COG0716	FMN binding
ECDH1ME8569_RS14890	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ECDH1ME8569_RS14900	COG1272	protein, Hemolysin III
ECDH1ME8569_RS14910	COG2723	6-phospho-beta-galactosidase activity
ECDH1ME8569_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS14935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECDH1ME8569_RS14940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECDH1ME8569_RS14945	COG0006	proline dipeptidase activity
ECDH1ME8569_RS14960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ECDH1ME8569_RS14965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECDH1ME8569_RS14985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECDH1ME8569_RS14985	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECDH1ME8569_RS14990	COG1703	isobutyryl-CoA mutase activity
ECDH1ME8569_RS14995	COG1024	Enoyl-CoA hydratase
ECDH1ME8569_RS15000	COG0427	acetyl-CoA hydrolase
ECDH1ME8569_RS15005	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS15010	COG2968	Membrane
ECDH1ME8569_RS15015	COG1279	arginine transmembrane transporter activity
ECDH1ME8569_RS15020	COG0668	transmembrane transport
ECDH1ME8569_RS15025	COG0191	fructose-bisphosphate aldolase activity
ECDH1ME8569_RS15040	COG1072	(Pantothenic acid kinase))
ECDH1ME8569_RS15045	COG3722	fumarate hydratase activity
ECDH1ME8569_RS15050	COG1494	fructose-1,6-bisphosphatase
ECDH1ME8569_RS15055	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS15060	COG2213	PTS system mannitol-specific
ECDH1ME8569_RS15065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS15070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECDH1ME8569_RS15075	COG0501	Belongs to the peptidase M48B family
ECDH1ME8569_RS15085	COG1166	arginine decarboxylase activity
ECDH1ME8569_RS15110	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS15120	COG2356	endonuclease I
ECDH1ME8569_RS15125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ECDH1ME8569_RS15130	COG0189	ligase activity
ECDH1ME8569_RS15145	COG2805	Type II/IV secretion system protein
ECDH1ME8569_RS15150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ECDH1ME8569_RS15155	COG0762	integral membrane protein
ECDH1ME8569_RS15165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ECDH1ME8569_RS15170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECDH1ME8569_RS15180	COG0252	asparaginase activity
ECDH1ME8569_RS15195	COG3171	Protein conserved in bacteria
ECDH1ME8569_RS15205	COG1194	a g-specific adenine glycosylase
ECDH1ME8569_RS15220	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS15225	COG1982	Orn Lys Arg decarboxylase major
ECDH1ME8569_RS15230	COG1811	Na channel or pump
ECDH1ME8569_RS15240	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECDH1ME8569_RS15250	COG3031	protein transport across the cell outer membrane
ECDH1ME8569_RS15260	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ECDH1ME8569_RS15265	COG3064	Membrane
ECDH1ME8569_RS15275	COG1620	l-lactate permease
ECDH1ME8569_RS15280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECDH1ME8569_RS15285	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ECDH1ME8569_RS15290	COG0247	lactate metabolic process
ECDH1ME8569_RS15295	COG0277	FAD linked oxidase domain protein
ECDH1ME8569_RS15300	COG0277	FAD linked oxidase domain protein
ECDH1ME8569_RS15305	COG2186	Transcriptional regulator
ECDH1ME8569_RS15310	COG0456	acetyltransferase
ECDH1ME8569_RS15320	COG2244	polysaccharide biosynthetic process
ECDH1ME8569_RS15325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECDH1ME8569_RS15330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECDH1ME8569_RS15335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECDH1ME8569_RS15340	COG0306	phosphate transporter
ECDH1ME8569_RS15345	COG0754	glutathionylspermidine amidase activity
ECDH1ME8569_RS15350	COG0625	glutathione transferase activity
ECDH1ME8569_RS15355	COG0298	carbon dioxide binding
ECDH1ME8569_RS15365	COG1773	rubredoxin
ECDH1ME8569_RS15370	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECDH1ME8569_RS15375	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECDH1ME8569_RS15380	COG5557	Pfam Polysulphide reductase, NrfD
ECDH1ME8569_RS15385	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS15390	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECDH1ME8569_RS15410	COG0667	Aldo Keto reductase
ECDH1ME8569_RS15420	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS15425	COG0848	biopolymer transport protein
ECDH1ME8569_RS15430	COG0811	peptide transport
ECDH1ME8569_RS15440	COG0626	cystathionine gamma-synthase activity
ECDH1ME8569_RS15445	COG0586	Pfam SNARE associated Golgi protein
ECDH1ME8569_RS15450	COG2207	Transcriptional regulator
ECDH1ME8569_RS15460	COG1979	alcohol dehydrogenase
ECDH1ME8569_RS15465	COG0656	L-ascorbic acid biosynthetic process
ECDH1ME8569_RS15475	COG4238	major outer membrane lipoprotein
ECDH1ME8569_RS15480	COG1032	radical SAM domain protein
ECDH1ME8569_RS15490	COG0204	Acyl-transferase
ECDH1ME8569_RS15495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECDH1ME8569_RS15500	COG4166	transmembrane transport
ECDH1ME8569_RS15505	COG2944	sequence-specific DNA binding
ECDH1ME8569_RS15515	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECDH1ME8569_RS15520	COG3111	PFAM Bacterial OB fold (BOF) protein
ECDH1ME8569_RS15525	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS15530	COG0642	Histidine kinase
ECDH1ME8569_RS15540	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECDH1ME8569_RS15545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ECDH1ME8569_RS15550	COG0187	DNA topoisomerase II activity
ECDH1ME8569_RS15555	COG3150	esterase
ECDH1ME8569_RS15560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ECDH1ME8569_RS15565	COG3151	Protein conserved in bacteria
ECDH1ME8569_RS15570	COG0494	nUDIX hydrolase
ECDH1ME8569_RS15575	COG1538	Outer membrane efflux protein
ECDH1ME8569_RS15590	COG0754	glutathionylspermidine amidase activity
ECDH1ME8569_RS15595	COG3384	dioxygenase
ECDH1ME8569_RS15615	COG2960	long-chain fatty acid transporting porin activity
ECDH1ME8569_RS15620	COG3539	Fimbrial protein
ECDH1ME8569_RS15635	COG3188	usher protein
ECDH1ME8569_RS15640	COG3121	Chaperone
ECDH1ME8569_RS15645	COG3539	Fimbrial protein
ECDH1ME8569_RS15655	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECDH1ME8569_RS15660	COG2268	Band 7 protein
ECDH1ME8569_RS15685	COG3025	triphosphatase activity
ECDH1ME8569_RS15695	COG4991	sh3 domain protein
ECDH1ME8569_RS15710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECDH1ME8569_RS15720	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS15725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECDH1ME8569_RS15735	COG0471	metal ion transport
ECDH1ME8569_RS15745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ECDH1ME8569_RS15750	COG0358	DNA primase activity
ECDH1ME8569_RS15755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECDH1ME8569_RS15770	COG2375	cellular response to nickel ion
ECDH1ME8569_RS15775	COG1695	Transcriptional regulator
ECDH1ME8569_RS15780	COG0840	transmembrane signaling receptor activity
ECDH1ME8569_RS15790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECDH1ME8569_RS15795	COG1609	Transcriptional regulator
ECDH1ME8569_RS15800	COG3250	beta-galactosidase activity
ECDH1ME8569_RS15805	COG2731	YhcH YjgK YiaL family protein
ECDH1ME8569_RS15810	COG0531	amino acid
ECDH1ME8569_RS15820	COG3408	Glycogen debranching enzyme
ECDH1ME8569_RS15820	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ECDH1ME8569_RS15825	COG1902	pentaerythritol trinitrate reductase activity
ECDH1ME8569_RS15825	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECDH1ME8569_RS15830	COG5499	transcription regulator containing HTH domain
ECDH1ME8569_RS15835	COG4680	protein conserved in bacteria
ECDH1ME8569_RS15850	COG1451	nucleotide metabolic process
ECDH1ME8569_RS15855	COG2949	membrane
ECDH1ME8569_RS15860	COG0673	inositol 2-dehydrogenase activity
ECDH1ME8569_RS15865	COG0861	Integral membrane protein TerC family
ECDH1ME8569_RS15870	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ECDH1ME8569_RS15880	COG2721	sulfolactate sulfo-lyase activity
ECDH1ME8569_RS15890	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS15895	COG2186	Transcriptional regulator
ECDH1ME8569_RS15900	COG0586	Pfam SNARE associated Golgi protein
ECDH1ME8569_RS15910	COG1422	Protein of unknown function (DUF1090)
ECDH1ME8569_RS15915	COG4575	ribosome binding
ECDH1ME8569_RS15920	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ECDH1ME8569_RS15930	COG2259	Doxx family
ECDH1ME8569_RS15935	COG0435	Glutathione S-transferase
ECDH1ME8569_RS15940	COG3152	Membrane
ECDH1ME8569_RS15945	COG3152	Membrane
ECDH1ME8569_RS15950	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS15955	COG1741	Belongs to the pirin family
ECDH1ME8569_RS15970	COG0814	amino acid
ECDH1ME8569_RS15975	COG1760	l-serine dehydratase
ECDH1ME8569_RS15980	COG0251	oxidation-reduction process
ECDH1ME8569_RS15985	COG1882	Formate acetyltransferase
ECDH1ME8569_RS15990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECDH1ME8569_RS16000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECDH1ME8569_RS16005	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS16025	COG1929	Belongs to the glycerate kinase type-1 family
ECDH1ME8569_RS16030	COG2084	Dehydrogenase
ECDH1ME8569_RS16040	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS16045	COG2721	sulfolactate sulfo-lyase activity
ECDH1ME8569_RS16050	COG2002	toxin-antitoxin pair type II binding
ECDH1ME8569_RS16060	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS16070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS16080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECDH1ME8569_RS16085	COG2222	sugar isomerase
ECDH1ME8569_RS16095	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS16100	COG3715	PTS system
ECDH1ME8569_RS16105	COG3716	PTS system mannose fructose sorbose family IID component
ECDH1ME8569_RS16110	COG0363	glucosamine-6-phosphate deaminase activity
ECDH1ME8569_RS16115	COG3539	Fimbrial protein
ECDH1ME8569_RS16120	COG3121	Chaperone
ECDH1ME8569_RS16125	COG3188	usher protein
ECDH1ME8569_RS16130	COG3539	Fimbrial protein
ECDH1ME8569_RS16135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECDH1ME8569_RS16140	COG3107	peptidoglycan biosynthetic process
ECDH1ME8569_RS16155	COG2823	Periplasmic or secreted lipoprotein
ECDH1ME8569_RS16160	COG0701	Predicted permease
ECDH1ME8569_RS16165	COG0702	epimerase
ECDH1ME8569_RS16170	COG0693	protein deglycase activity
ECDH1ME8569_RS16185	COG3153	acetyltransferase
ECDH1ME8569_RS16190	COG3154	lipid carrier protein
ECDH1ME8569_RS16195	COG0826	peptidase U32
ECDH1ME8569_RS16200	COG0826	peptidase U32
ECDH1ME8569_RS16205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECDH1ME8569_RS16210	COG0814	amino acid
ECDH1ME8569_RS16220	COG0513	Belongs to the DEAD box helicase family
ECDH1ME8569_RS16255	COG0195	Participates in both transcription termination and antitermination
ECDH1ME8569_RS16275	COG2194	sulfuric ester hydrolase activity
ECDH1ME8569_RS16285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECDH1ME8569_RS16295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ECDH1ME8569_RS16300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ECDH1ME8569_RS16310	COG1534	Rna-binding protein
ECDH1ME8569_RS16315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECDH1ME8569_RS16320	COG2027	D-alanyl-D-alanine carboxypeptidase
ECDH1ME8569_RS16330	COG0697	spore germination
ECDH1ME8569_RS16345	COG0142	geranyltranstransferase activity
ECDH1ME8569_RS16350	COG3423	Transcriptional regulator
ECDH1ME8569_RS16360	COG5007	Belongs to the BolA IbaG family
ECDH1ME8569_RS16365	COG3113	response to antibiotic
ECDH1ME8569_RS16370	COG2854	intermembrane phospholipid transfer
ECDH1ME8569_RS16375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECDH1ME8569_RS16380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ECDH1ME8569_RS16385	COG1127	ABC transporter
ECDH1ME8569_RS16390	COG0530	calcium, potassium:sodium antiporter activity
ECDH1ME8569_RS16395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECDH1ME8569_RS16395	COG0517	IMP dehydrogenase activity
ECDH1ME8569_RS16400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ECDH1ME8569_RS16405	COG3117	lipopolysaccharide transmembrane transporter activity
ECDH1ME8569_RS16410	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ECDH1ME8569_RS16415	COG1137	ATPase activity
ECDH1ME8569_RS16420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ECDH1ME8569_RS16425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECDH1ME8569_RS16440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS16445	COG0515	serine threonine protein kinase
ECDH1ME8569_RS16455	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ECDH1ME8569_RS16460	COG5002	protein histidine kinase activity
ECDH1ME8569_RS16460	COG2198	Histidine kinase
ECDH1ME8569_RS16460	COG0784	Response regulator, receiver
ECDH1ME8569_RS16465	COG1242	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS16470	COG0070	glutamate synthase
ECDH1ME8569_RS16470	COG0067	glutamate synthase
ECDH1ME8569_RS16470	COG0069	glutamate synthase activity
ECDH1ME8569_RS16475	COG0493	'glutamate synthase
ECDH1ME8569_RS16480	COG3539	Fimbrial protein
ECDH1ME8569_RS16485	COG3121	Chaperone
ECDH1ME8569_RS16490	COG3188	usher protein
ECDH1ME8569_RS16510	COG3539	Fimbrial protein
ECDH1ME8569_RS16515	COG4804	nuclease activity
ECDH1ME8569_RS16520	COG2731	YhcH YjgK YiaL family protein
ECDH1ME8569_RS16550	COG3069	C4-dicarboxylate transmembrane transporter activity
ECDH1ME8569_RS16555	COG2969	positive regulation of protein catabolic process
ECDH1ME8569_RS16560	COG0625	glutathione transferase activity
ECDH1ME8569_RS16575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ECDH1ME8569_RS16580	COG3105	Protein conserved in bacteria
ECDH1ME8569_RS16585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECDH1ME8569_RS16590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECDH1ME8569_RS16610	COG2732	(Barnase) inhibitor
ECDH1ME8569_RS16630	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS16635	COG0312	modulator of DNA gyrase
ECDH1ME8569_RS16640	COG3164	Protein of unknown function
ECDH1ME8569_RS16645	COG1530	ribonuclease E activity
ECDH1ME8569_RS16650	COG0424	maF-like protein
ECDH1ME8569_RS16655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ECDH1ME8569_RS16660	COG1792	Involved in formation and maintenance of cell shape
ECDH1ME8569_RS16665	COG1077	Cell shape determining protein MreB Mrl
ECDH1ME8569_RS16675	COG2200	EAL domain
ECDH1ME8569_RS16675	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS16680	COG0604	alcohol dehydrogenase
ECDH1ME8569_RS16700	COG0511	ligase activity, forming carbon-carbon bonds
ECDH1ME8569_RS16705	COG0439	Biotin carboxylase
ECDH1ME8569_RS16710	COG3924	membrane
ECDH1ME8569_RS16715	COG4145	pantothenate transmembrane transporter activity
ECDH1ME8569_RS16725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECDH1ME8569_RS16735	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ECDH1ME8569_RS16745	COG1309	transcriptional regulator
ECDH1ME8569_RS16750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECDH1ME8569_RS16755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECDH1ME8569_RS16770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECDH1ME8569_RS16775	COG4597	amino acid ABC transporter
ECDH1ME8569_RS16780	COG0765	amino acid transport
ECDH1ME8569_RS16785	COG1126	abc transporter atp-binding protein
ECDH1ME8569_RS16825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECDH1ME8569_RS16845	COG0551	DNA topoisomerase type I activity
ECDH1ME8569_RS16855	COG0758	DNA mediated transformation
ECDH1ME8569_RS16885	COG3036	rescue of stalled ribosome
ECDH1ME8569_RS16890	COG0789	Transcriptional regulator
ECDH1ME8569_RS16930	COG0201	protein transport
ECDH1ME8569_RS17020	COG0089	rRNA binding
ECDH1ME8569_RS17045	COG3267	Type II secretory pathway component ExeA
ECDH1ME8569_RS17045	COG3409	Peptidoglycan-binding domain 1 protein
ECDH1ME8569_RS17050	COG3031	protein transport across the cell outer membrane
ECDH1ME8569_RS17055	COG1450	Type ii and iii secretion system protein
ECDH1ME8569_RS17060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECDH1ME8569_RS17065	COG1459	type II secretion system
ECDH1ME8569_RS17070	COG2165	general secretion pathway protein
ECDH1ME8569_RS17075	COG2165	general secretion pathway protein
ECDH1ME8569_RS17080	COG2165	general secretion pathway protein
ECDH1ME8569_RS17085	COG4795	General secretion pathway protein
ECDH1ME8569_RS17090	COG3156	type II secretion system protein K
ECDH1ME8569_RS17095	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECDH1ME8569_RS17100	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECDH1ME8569_RS17105	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ECDH1ME8569_RS17110	COG2193	ferroxidase activity
ECDH1ME8569_RS17115	COG2906	2 iron, 2 sulfur cluster binding
ECDH1ME8569_RS17120	COG3979	chitinase
ECDH1ME8569_RS17160	COG2964	Protein conserved in bacteria
ECDH1ME8569_RS17165	COG0545	Peptidyl-prolyl cis-trans isomerase
ECDH1ME8569_RS17175	COG1047	Peptidyl-prolyl cis-trans
ECDH1ME8569_RS17180	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ECDH1ME8569_RS17195	COG0488	(ABC) transporter
ECDH1ME8569_RS17200	COG0429	hydrolase of the alpha beta-hydrolase fold
ECDH1ME8569_RS17210	COG3954	Phosphoribulokinase
ECDH1ME8569_RS17215	COG1765	OsmC-like protein
ECDH1ME8569_RS17225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECDH1ME8569_RS17230	COG1289	transmembrane transporter activity
ECDH1ME8569_RS17235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ECDH1ME8569_RS17240	COG0512	Glutamine amidotransferase of anthranilate synthase
ECDH1ME8569_RS17245	COG2184	nucleotidyltransferase activity
ECDH1ME8569_RS17255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECDH1ME8569_RS17265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECDH1ME8569_RS17270	COG2146	nitrite reductase [NAD(P)H] activity
ECDH1ME8569_RS17275	COG2116	formate transmembrane transporter activity
ECDH1ME8569_RS17290	COG0531	amino acid
ECDH1ME8569_RS17295	COG2222	sugar isomerase
ECDH1ME8569_RS17300	COG1082	Xylose isomerase domain protein TIM barrel
ECDH1ME8569_RS17305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS17310	COG2188	Transcriptional regulator
ECDH1ME8569_RS17315	COG0626	cystathionine gamma-synthase activity
ECDH1ME8569_RS17330	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ECDH1ME8569_RS17335	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ECDH1ME8569_RS17340	COG3457	Alanine racemase
ECDH1ME8569_RS17350	COG2188	Transcriptional regulator
ECDH1ME8569_RS17355	COG0180	Tryptophanyl-tRNA synthetase
ECDH1ME8569_RS17360	COG0546	phosphoglycolate phosphatase activity
ECDH1ME8569_RS17365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECDH1ME8569_RS17370	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ECDH1ME8569_RS17375	COG3266	domain, Protein
ECDH1ME8569_RS17390	COG4796	Type ii and iii secretion system protein
ECDH1ME8569_RS17405	COG3166	PFAM Fimbrial assembly family protein
ECDH1ME8569_RS17410	COG4972	Pilus assembly protein
ECDH1ME8569_RS17415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ECDH1ME8569_RS17420	COG0494	nUDIX hydrolase
ECDH1ME8569_RS17430	COG1011	Hydrolase
ECDH1ME8569_RS17435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ECDH1ME8569_RS17445	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECDH1ME8569_RS17470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECDH1ME8569_RS17475	COG2183	response to ionizing radiation
ECDH1ME8569_RS17480	COG1918	ferrous iron import across plasma membrane
ECDH1ME8569_RS17485	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ECDH1ME8569_RS17495	COG5464	transposase or invertase
ECDH1ME8569_RS17505	COG1040	competence protein
ECDH1ME8569_RS17515	COG2610	gluconate transmembrane transporter activity
ECDH1ME8569_RS17520	COG1640	4-alpha-glucanotransferase
ECDH1ME8569_RS17525	COG0058	SHG alpha-glucan phosphorylase activity
ECDH1ME8569_RS17540	COG1690	Belongs to the RtcB family
ECDH1ME8569_RS17545	COG4650	regulator
ECDH1ME8569_RS17550	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS17565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECDH1ME8569_RS17570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECDH1ME8569_RS17575	COG0058	SHG alpha-glucan phosphorylase activity
ECDH1ME8569_RS17600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECDH1ME8569_RS17605	COG2095	MarC family integral membrane protein
ECDH1ME8569_RS17610	COG2610	gluconate transmembrane transporter activity
ECDH1ME8569_RS17615	COG3265	gluconokinase activity
ECDH1ME8569_RS17620	COG1609	Transcriptional regulator
ECDH1ME8569_RS17625	COG1741	Belongs to the pirin family
ECDH1ME8569_RS17630	COG0673	inositol 2-dehydrogenase activity
ECDH1ME8569_RS17635	COG1247	-acetyltransferase
ECDH1ME8569_RS17640	COG3157	Type VI secretion system effector, Hcp
ECDH1ME8569_RS17660	COG0405	Gamma-glutamyltransferase
ECDH1ME8569_RS17670	COG0584	glycerophosphoryl diester phosphodiesterase
ECDH1ME8569_RS17675	COG3842	ATPase activity
ECDH1ME8569_RS17680	COG0395	ABC-type sugar transport system, permease component
ECDH1ME8569_RS17685	COG1175	transmembrane transport
ECDH1ME8569_RS17690	COG1653	transport
ECDH1ME8569_RS17700	COG0410	ABC transporter
ECDH1ME8569_RS17705	COG0411	ABC transporter
ECDH1ME8569_RS17710	COG4177	L-phenylalanine transmembrane transporter activity
ECDH1ME8569_RS17715	COG0559	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS17720	COG0683	leucine binding
ECDH1ME8569_RS17725	COG0456	acetyltransferase
ECDH1ME8569_RS17735	COG0683	leucine binding
ECDH1ME8569_RS17740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECDH1ME8569_RS17745	COG2177	Part of the ABC transporter FtsEX involved in
ECDH1ME8569_RS17750	COG2884	Cell division ATP-binding protein ftsE
ECDH1ME8569_RS17755	COG0552	protein localization to endoplasmic reticulum
ECDH1ME8569_RS17760	COG0742	ribosomal rna small subunit methyltransferase
ECDH1ME8569_RS17765	COG3776	membrane
ECDH1ME8569_RS17775	COG3714	YhhN family
ECDH1ME8569_RS17780	COG2217	Heavy metal translocating P-type atpase
ECDH1ME8569_RS17790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ECDH1ME8569_RS17800	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS17805	COG0628	permease
ECDH1ME8569_RS17810	COG2091	lysine biosynthetic process via aminoadipic acid
ECDH1ME8569_RS17815	COG0747	negative chemotaxis
ECDH1ME8569_RS17820	COG0601	transmembrane transport
ECDH1ME8569_RS17825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECDH1ME8569_RS17830	COG0444	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS17835	COG1124	(ABC) transporter
ECDH1ME8569_RS17845	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS17860	COG5433	transposase activity
ECDH1ME8569_RS17865	COG0842	Transport permease protein
ECDH1ME8569_RS17870	COG1129	ABC transporter
ECDH1ME8569_RS17870	COG0842	Transport permease protein
ECDH1ME8569_RS17875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECDH1ME8569_RS17905	COG2081	HI0933 family
ECDH1ME8569_RS17910	COG0306	phosphate transporter
ECDH1ME8569_RS17920	COG0589	response to stress
ECDH1ME8569_RS17925	COG3104	oligopeptide transport
ECDH1ME8569_RS17935	COG0339	signal peptide processing
ECDH1ME8569_RS17940	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ECDH1ME8569_RS17945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECDH1ME8569_RS17960	COG0640	Transcriptional regulator
ECDH1ME8569_RS17965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECDH1ME8569_RS17970	COG1393	Belongs to the ArsC family
ECDH1ME8569_RS17990	COG3065	identical protein binding
ECDH1ME8569_RS17995	COG2197	response regulator
ECDH1ME8569_RS18000	COG1285	pathogenesis
ECDH1ME8569_RS18015	COG3247	response to pH
ECDH1ME8569_RS18020	COG2771	luxR family
ECDH1ME8569_RS18030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECDH1ME8569_RS18035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECDH1ME8569_RS18040	COG2207	Transcriptional regulator
ECDH1ME8569_RS18045	COG2207	Transcriptional regulator
ECDH1ME8569_RS18050	COG0076	glutamate decarboxylase activity
ECDH1ME8569_RS18055	COG1858	cytochrome C peroxidase
ECDH1ME8569_RS18065	COG2197	response regulator
ECDH1ME8569_RS18070	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS18075	COG1295	ribonuclease BN
ECDH1ME8569_RS18080	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS18085	COG2982	Protein involved in outer membrane biogenesis
ECDH1ME8569_RS18090	COG2200	EAL domain
ECDH1ME8569_RS18100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS18105	COG0612	Peptidase, M16
ECDH1ME8569_RS18115	COG2200	EAL domain
ECDH1ME8569_RS18115	COG2199	diguanylate cyclase activity
ECDH1ME8569_RS18120	COG0457	Tetratricopeptide repeat
ECDH1ME8569_RS18120	COG3118	belongs to the thioredoxin family
ECDH1ME8569_RS18125	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ECDH1ME8569_RS18130	COG1215	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS18135	COG1215	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS18160	COG2194	sulfuric ester hydrolase activity
ECDH1ME8569_RS18175	COG0814	amino acid
ECDH1ME8569_RS18180	COG4608	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS18185	COG0444	Belongs to the ABC transporter superfamily
ECDH1ME8569_RS18190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECDH1ME8569_RS18195	COG0601	transmembrane transport
ECDH1ME8569_RS18205	COG0747	negative chemotaxis
ECDH1ME8569_RS18220	COG2194	sulfuric ester hydrolase activity
ECDH1ME8569_RS18225	COG2223	nitrite transmembrane transporter activity
ECDH1ME8569_RS18230	COG5571	outer membrane autotransporter
ECDH1ME8569_RS18235	COG2818	Glycosylase
ECDH1ME8569_RS18240	COG0456	acetyltransferase
ECDH1ME8569_RS18245	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS18250	COG2885	chlorophyll binding
ECDH1ME8569_RS18265	COG2944	sequence-specific DNA binding
ECDH1ME8569_RS18270	COG1278	Cold shock
ECDH1ME8569_RS18280	COG2963	transposase activity
ECDH1ME8569_RS18285	COG2801	Transposase and inactivated derivatives
ECDH1ME8569_RS18305	COG3274	enterobacterial common antigen metabolic process
ECDH1ME8569_RS18310	COG4682	membrane
ECDH1ME8569_RS18315	COG4682	membrane
ECDH1ME8569_RS18320	COG1070	Carbohydrate kinase
ECDH1ME8569_RS18330	COG4213	ABC transporter substrate-binding protein
ECDH1ME8569_RS18335	COG1129	ABC transporter
ECDH1ME8569_RS18340	COG4214	carbohydrate transport
ECDH1ME8569_RS18345	COG1609	Transcriptional regulator
ECDH1ME8569_RS18345	COG2207	Transcriptional regulator
ECDH1ME8569_RS18350	COG2992	FlgJ-related protein
ECDH1ME8569_RS18355	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS18360	COG3977	Valine--pyruvate aminotransferase
ECDH1ME8569_RS18370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECDH1ME8569_RS18375	COG1414	Transcriptional regulator
ECDH1ME8569_RS18385	COG2731	YhcH YjgK YiaL family protein
ECDH1ME8569_RS18390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECDH1ME8569_RS18395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECDH1ME8569_RS18400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECDH1ME8569_RS18405	COG1070	Carbohydrate kinase
ECDH1ME8569_RS18410	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ECDH1ME8569_RS18415	COG3623	hexulose-6-phosphate isomerase
ECDH1ME8569_RS18420	COG0235	Class ii aldolase
ECDH1ME8569_RS18425	COG3713	MltA-interacting MipA family protein
ECDH1ME8569_RS18430	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS18435	COG1566	PFAM secretion protein HlyD family protein
ECDH1ME8569_RS18450	COG1012	belongs to the aldehyde dehydrogenase family
ECDH1ME8569_RS18455	COG1454	alcohol dehydrogenase
ECDH1ME8569_RS18460	COG3276	selenocysteine insertion sequence binding
ECDH1ME8569_RS18470	COG0625	glutathione transferase activity
ECDH1ME8569_RS18475	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS18480	COG1413	lyase activity
ECDH1ME8569_RS18485	COG3209	COG3209 Rhs family protein
ECDH1ME8569_RS18490	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECDH1ME8569_RS18500	COG1566	PFAM secretion protein HlyD family protein
ECDH1ME8569_RS18510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS18510	COG2213	PTS system mannitol-specific
ECDH1ME8569_RS18520	COG3722	fumarate hydratase activity
ECDH1ME8569_RS18535	COG1620	l-lactate permease
ECDH1ME8569_RS18540	COG2186	Transcriptional regulator
ECDH1ME8569_RS18550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ECDH1ME8569_RS18555	COG1045	serine acetyltransferase
ECDH1ME8569_RS18570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECDH1ME8569_RS18575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECDH1ME8569_RS18580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ECDH1ME8569_RS18585	COG4942	peptidase
ECDH1ME8569_RS18590	COG2861	carbohydrate metabolic process
ECDH1ME8569_RS18595	COG1216	Glycosyl transferase, family 2
ECDH1ME8569_RS18605	COG0156	8-amino-7-oxononanoate synthase activity
ECDH1ME8569_RS18620	COG0859	PFAM glycosyl transferase family 9
ECDH1ME8569_RS18625	COG0859	PFAM glycosyl transferase family 9
ECDH1ME8569_RS18630	COG3307	-O-antigen
ECDH1ME8569_RS18635	COG0859	PFAM glycosyl transferase family 9
ECDH1ME8569_RS18645	COG3642	lipopolysaccharide core region biosynthetic process
ECDH1ME8569_RS18650	COG1442	glycosyl transferase family 8
ECDH1ME8569_RS18655	COG1442	glycosyl transferase family 8
ECDH1ME8569_RS18660	COG0438	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS18665	COG0438	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS18665	COG4641	Protein conserved in bacteria
ECDH1ME8569_RS18670	COG0515	serine threonine protein kinase
ECDH1ME8569_RS18675	COG0438	transferase activity, transferring glycosyl groups
ECDH1ME8569_RS18680	COG0859	PFAM glycosyl transferase family 9
ECDH1ME8569_RS18685	COG1519	Transferase
ECDH1ME8569_RS18715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECDH1ME8569_RS18720	COG0756	dUTP diphosphatase activity
ECDH1ME8569_RS18740	COG1561	YicC-like family, N-terminal region
ECDH1ME8569_RS18745	COG3645	SOS response
ECDH1ME8569_RS18750	COG2860	membrane
ECDH1ME8569_RS18760	COG0194	GDP metabolic process
ECDH1ME8569_RS18770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECDH1ME8569_RS18775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECDH1ME8569_RS18780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECDH1ME8569_RS18785	COG0786	glutamate:sodium symporter activity
ECDH1ME8569_RS18790	COG2233	PERMEase
ECDH1ME8569_RS18795	COG2982	Protein involved in outer membrane biogenesis
ECDH1ME8569_RS18800	COG1501	Belongs to the glycosyl hydrolase 31 family
ECDH1ME8569_RS18805	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS18820	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS18825	COG0697	spore germination
ECDH1ME8569_RS18830	COG1464	Belongs to the NlpA lipoprotein family
ECDH1ME8569_RS18855	COG2252	PERMEase
ECDH1ME8569_RS18865	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS18870	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS18875	COG3851	Histidine kinase
ECDH1ME8569_RS18880	COG2197	response regulator
ECDH1ME8569_RS18885	COG0440	acetolactate synthase activity
ECDH1ME8569_RS18890	COG0028	Belongs to the TPP enzyme family
ECDH1ME8569_RS18915	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS18920	COG0641	radical SAM
ECDH1ME8569_RS18930	COG2149	membrane
ECDH1ME8569_RS18940	COG3119	arylsulfatase activity
ECDH1ME8569_RS18945	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECDH1ME8569_RS18950	COG2207	Transcriptional regulator
ECDH1ME8569_RS18960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS18960	COG1263	PTS System
ECDH1ME8569_RS18965	COG1263	PTS System
ECDH1ME8569_RS18970	COG2188	Transcriptional regulator
ECDH1ME8569_RS18990	COG5645	(Lipo)protein
ECDH1ME8569_RS18995	COG0823	Involved in the tonB-independent uptake of proteins
ECDH1ME8569_RS19000	COG0644	oxidoreductase
ECDH1ME8569_RS19005	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS19015	COG0800	Aldolase
ECDH1ME8569_RS19020	COG3734	2-keto-3-deoxy-galactonokinase
ECDH1ME8569_RS19025	COG2186	Transcriptional regulator
ECDH1ME8569_RS19035	COG0561	phosphatase activity
ECDH1ME8569_RS19040	COG3753	Protein conserved in bacteria
ECDH1ME8569_RS19050	COG0187	DNA topoisomerase II activity
ECDH1ME8569_RS19060	COG0592	DNA-directed DNA polymerase activity
ECDH1ME8569_RS19105	COG0814	amino acid
ECDH1ME8569_RS19115	COG0814	amino acid
ECDH1ME8569_RS19130	COG2091	lysine biosynthetic process via aminoadipic acid
ECDH1ME8569_RS19135	COG0431	NADPH-dependent FMN reductase
ECDH1ME8569_RS19140	COG2252	PERMEase
ECDH1ME8569_RS19145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECDH1ME8569_RS19155	COG3196	Protein conserved in bacteria
ECDH1ME8569_RS19160	COG0363	glucosamine-6-phosphate deaminase activity
ECDH1ME8569_RS19165	COG2382	esterase
ECDH1ME8569_RS19175	COG2723	6-phospho-beta-galactosidase activity
ECDH1ME8569_RS19180	COG1263	PTS System
ECDH1ME8569_RS19180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS19180	COG2190	(PTS) system
ECDH1ME8569_RS19185	COG3711	transcriptional antiterminator
ECDH1ME8569_RS19190	COG0704	Plays a role in the regulation of phosphate uptake
ECDH1ME8569_RS19195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ECDH1ME8569_RS19200	COG0581	inorganic phosphate transmembrane transporter activity
ECDH1ME8569_RS19205	COG0573	inorganic phosphate transmembrane transporter activity
ECDH1ME8569_RS19210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECDH1ME8569_RS19215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ECDH1ME8569_RS19265	COG3312	ion transport
ECDH1ME8569_RS19280	COG0716	FMN binding
ECDH1ME8569_RS19285	COG1522	sequence-specific DNA binding
ECDH1ME8569_RS19315	COG1129	ABC transporter
ECDH1ME8569_RS19320	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS19325	COG1879	ABC-type sugar transport system periplasmic component
ECDH1ME8569_RS19330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS19340	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS19345	COG2186	Transcriptional regulator
ECDH1ME8569_RS19385	COG3085	chromosome segregation
ECDH1ME8569_RS19390	COG0606	chelatase, subunit chli
ECDH1ME8569_RS19405	COG3978	acetolactate synthase activity
ECDH1ME8569_RS19410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECDH1ME8569_RS19420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECDH1ME8569_RS19425	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS19435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECDH1ME8569_RS19445	COG0210	DNA helicase
ECDH1ME8569_RS19460	COG3118	belongs to the thioredoxin family
ECDH1ME8569_RS19470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECDH1ME8569_RS19480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECDH1ME8569_RS19485	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECDH1ME8569_RS19490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ECDH1ME8569_RS19495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ECDH1ME8569_RS19500	COG1088	dTDP-glucose 4,6-dehydratase activity
ECDH1ME8569_RS19505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ECDH1ME8569_RS19510	COG0456	acetyltransferase
ECDH1ME8569_RS19515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ECDH1ME8569_RS19520	COG2244	polysaccharide biosynthetic process
ECDH1ME8569_RS19540	COG1113	amino acid transport
ECDH1ME8569_RS19565	COG0641	radical SAM
ECDH1ME8569_RS19570	COG3119	arylsulfatase activity
ECDH1ME8569_RS19575	COG3071	HemY protein
ECDH1ME8569_RS19580	COG2959	enzyme of heme biosynthesis
ECDH1ME8569_RS19585	COG1587	Uroporphyrinogen-III synthase
ECDH1ME8569_RS19595	COG3072	Adenylate cyclase
ECDH1ME8569_RS19605	COG5567	small periplasmic lipoprotein
ECDH1ME8569_RS19615	COG3159	Protein conserved in bacteria
ECDH1ME8569_RS19625	COG1011	Hydrolase
ECDH1ME8569_RS19630	COG0210	DNA helicase
ECDH1ME8569_RS19635	COG3698	Phosphodiester glycosidase
ECDH1ME8569_RS19645	COG0598	Magnesium transport protein CorA
ECDH1ME8569_RS19660	COG2962	Rard protein
ECDH1ME8569_RS19665	COG2050	protein possibly involved in aromatic compounds catabolism
ECDH1ME8569_RS19670	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ECDH1ME8569_RS19675	COG0514	ATP-dependent DNA helicase (RecQ)
ECDH1ME8569_RS19680	COG1280	lysine exporter protein (LysE YggA)
ECDH1ME8569_RS19685	COG1280	lysine exporter protein (LysE YggA)
ECDH1ME8569_RS19690	COG2267	carboxylic ester hydrolase activity
ECDH1ME8569_RS19695	COG0561	phosphatase activity
ECDH1ME8569_RS19700	COG0697	spore germination
ECDH1ME8569_RS19705	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS19715	COG0412	Dienelactone hydrolase
ECDH1ME8569_RS19720	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ECDH1ME8569_RS19725	COG1322	Protein conserved in bacteria
ECDH1ME8569_RS19735	COG3165	ubiquinone biosynthetic process from chorismate
ECDH1ME8569_RS19745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECDH1ME8569_RS19750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECDH1ME8569_RS19755	COG0805	protein transport
ECDH1ME8569_RS19760	COG0084	hydrolase, TatD family'
ECDH1ME8569_RS19765	COG0250	Participates in transcription elongation, termination and antitermination
ECDH1ME8569_RS19770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECDH1ME8569_RS19775	COG0543	2 iron, 2 sulfur cluster binding
ECDH1ME8569_RS19780	COG0183	Belongs to the thiolase family
ECDH1ME8569_RS19795	COG1739	Uncharacterized protein family UPF0029
ECDH1ME8569_RS19800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECDH1ME8569_RS19805	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ECDH1ME8569_RS19835	COG1763	Mo-molybdopterin cofactor biosynthetic process
ECDH1ME8569_RS19840	COG0746	molybdenum cofactor guanylyltransferase activity
ECDH1ME8569_RS19845	COG3084	Protein conserved in bacteria
ECDH1ME8569_RS19850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ECDH1ME8569_RS19855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECDH1ME8569_RS19860	COG5339	Protein conserved in bacteria
ECDH1ME8569_RS19865	COG0204	Acyl-transferase
ECDH1ME8569_RS19875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECDH1ME8569_RS19875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECDH1ME8569_RS19890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECDH1ME8569_RS19900	COG2204	response regulator
ECDH1ME8569_RS19905	COG3852	Histidine kinase
ECDH1ME8569_RS19910	COG0174	glutamine synthetase
ECDH1ME8569_RS19920	COG1217	gtp-binding protein TYPA
ECDH1ME8569_RS19925	COG2188	Transcriptional regulator
ECDH1ME8569_RS19930	COG1082	Xylose isomerase domain protein TIM barrel
ECDH1ME8569_RS19935	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS19940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECDH1ME8569_RS19945	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS19950	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS19955	COG1501	Belongs to the glycosyl hydrolase 31 family
ECDH1ME8569_RS19960	COG2017	converts alpha-aldose to the beta-anomer
ECDH1ME8569_RS19965	COG2942	2-epimerase
ECDH1ME8569_RS19970	COG3684	Belongs to the aldolase LacD family
ECDH1ME8569_RS19975	COG2084	Dehydrogenase
ECDH1ME8569_RS19980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDH1ME8569_RS19985	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS19990	COG1011	Hydrolase
ECDH1ME8569_RS20005	COG0456	acetyltransferase
ECDH1ME8569_RS20010	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECDH1ME8569_RS20015	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECDH1ME8569_RS20030	COG2864	formate dehydrogenase
ECDH1ME8569_RS20035	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS20040	COG3383	formate dehydrogenase (NAD+) activity
ECDH1ME8569_RS20040	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS20045	COG3383	formate dehydrogenase (NAD+) activity
ECDH1ME8569_RS20045	COG0243	molybdopterin cofactor binding
ECDH1ME8569_RS20060	COG3711	transcriptional antiterminator
ECDH1ME8569_RS20060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS20065	COG1363	Peptidase, m42
ECDH1ME8569_RS20070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS20070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS20075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS20120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECDH1ME8569_RS20135	COG2258	MOSC domain
ECDH1ME8569_RS20140	COG2205	protein histidine kinase activity
ECDH1ME8569_RS20145	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS20150	COG3678	ATP-independent chaperone mediated protein folding
ECDH1ME8569_RS20165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ECDH1ME8569_RS20185	COG3152	Membrane
ECDH1ME8569_RS20190	COG3691	Protein conserved in bacteria
ECDH1ME8569_RS20195	COG0589	response to stress
ECDH1ME8569_RS20200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECDH1ME8569_RS20205	COG1494	fructose-1,6-bisphosphatase
ECDH1ME8569_RS20215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ECDH1ME8569_RS20230	COG1575	Belongs to the MenA family. Type 1 subfamily
ECDH1ME8569_RS20245	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECDH1ME8569_RS20250	COG1609	Transcriptional regulator
ECDH1ME8569_RS20255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ECDH1ME8569_RS20265	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ECDH1ME8569_RS20275	COG0626	cystathionine gamma-synthase activity
ECDH1ME8569_RS20280	COG0527	aspartate kinase activity
ECDH1ME8569_RS20280	COG0460	homoserine dehydrogenase
ECDH1ME8569_RS20290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ECDH1ME8569_RS20300	COG0697	spore germination
ECDH1ME8569_RS20305	COG3738	Protein conserved in bacteria
ECDH1ME8569_RS20315	COG0371	Dehydrogenase
ECDH1ME8569_RS20320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECDH1ME8569_RS20325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDH1ME8569_RS20325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS20325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS20330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS20335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS20340	COG1882	Formate acetyltransferase
ECDH1ME8569_RS20345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECDH1ME8569_RS20350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECDH1ME8569_RS20355	COG2207	Transcriptional regulator
ECDH1ME8569_RS20360	COG2194	sulfuric ester hydrolase activity
ECDH1ME8569_RS20380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ECDH1ME8569_RS20395	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS20420	COG4206	TonB-dependent receptor
ECDH1ME8569_RS20450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ECDH1ME8569_RS20455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ECDH1ME8569_RS20455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ECDH1ME8569_RS20495	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECDH1ME8569_RS20500	COG0250	Participates in transcription elongation, termination and antitermination
ECDH1ME8569_RS20540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ECDH1ME8569_RS20550	COG2104	thiamine diphosphate biosynthetic process
ECDH1ME8569_RS20555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECDH1ME8569_RS20590	COG3068	Protein conserved in bacteria
ECDH1ME8569_RS20605	COG3678	ATP-independent chaperone mediated protein folding
ECDH1ME8569_RS20610	COG4191	Histidine kinase
ECDH1ME8569_RS20615	COG2204	response regulator
ECDH1ME8569_RS20620	COG0151	Belongs to the GarS family
ECDH1ME8569_RS20655	COG0456	acetyltransferase
ECDH1ME8569_RS20665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECDH1ME8569_RS20670	COG2224	Isocitrate lyase
ECDH1ME8569_RS20685	COG1414	Transcriptional regulator
ECDH1ME8569_RS20690	COG1410	methionine synthase
ECDH1ME8569_RS20690	COG0646	methionine synthase
ECDH1ME8569_RS20695	COG1283	sodium-dependent phosphate transmembrane transporter activity
ECDH1ME8569_RS20705	COG1187	pseudouridine synthase activity
ECDH1ME8569_RS20715	COG0527	aspartate kinase activity
ECDH1ME8569_RS20740	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECDH1ME8569_RS20760	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS20760	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS20765	COG3833	ABC-type maltose transport systems, permease component
ECDH1ME8569_RS20770	COG1175	transmembrane transport
ECDH1ME8569_RS20775	COG2182	Extracellular solute-binding protein
ECDH1ME8569_RS20785	COG3842	ATPase activity
ECDH1ME8569_RS20805	COG1357	PFAM Pentapeptide repeats (8 copies)
ECDH1ME8569_RS20825	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ECDH1ME8569_RS20835	COG0534	Mate efflux family protein
ECDH1ME8569_RS20840	COG3237	CsbD-like
ECDH1ME8569_RS20845	COG0735	belongs to the Fur family
ECDH1ME8569_RS20860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECDH1ME8569_RS20870	COG0604	alcohol dehydrogenase
ECDH1ME8569_RS20875	COG0305	Participates in initiation and elongation during chromosome replication
ECDH1ME8569_RS20880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECDH1ME8569_RS20885	COG1448	Aminotransferase
ECDH1ME8569_RS20895	COG3700	Belongs to the class B bacterial acid phosphatase family
ECDH1ME8569_RS20900	COG0432	Pfam Uncharacterised protein family UPF0047
ECDH1ME8569_RS20905	COG2315	Protein conserved in bacteria
ECDH1ME8569_RS20910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ECDH1ME8569_RS20915	COG0629	single-stranded DNA binding
ECDH1ME8569_RS20925	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECDH1ME8569_RS20930	COG2207	Transcriptional regulator
ECDH1ME8569_RS20935	COG0789	Transcriptional regulator
ECDH1ME8569_RS20940	COG2252	PERMEase
ECDH1ME8569_RS20945	COG0025	NhaP-type Na H and K H
ECDH1ME8569_RS20950	COG1357	PFAM Pentapeptide repeats (8 copies)
ECDH1ME8569_RS20960	COG3162	membrane
ECDH1ME8569_RS20965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECDH1ME8569_RS20975	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ECDH1ME8569_RS20980	COG0437	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS20985	COG3301	Polysulphide reductase, NrfD
ECDH1ME8569_RS20990	COG1138	Cytochrome C-type biogenesis protein
ECDH1ME8569_RS20995	COG3088	subunit of a heme lyase
ECDH1ME8569_RS21000	COG4235	cytochrome complex assembly
ECDH1ME8569_RS21005	COG1301	dicarboxylic acid transport
ECDH1ME8569_RS21010	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECDH1ME8569_RS21015	COG3383	formate dehydrogenase (NAD+) activity
ECDH1ME8569_RS21020	COG3383	formate dehydrogenase (NAD+) activity
ECDH1ME8569_RS21025	COG1538	Outer membrane efflux protein
ECDH1ME8569_RS21030	COG1289	transmembrane transporter activity
ECDH1ME8569_RS21035	COG1566	PFAM secretion protein HlyD family protein
ECDH1ME8569_RS21045	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ECDH1ME8569_RS21050	COG1940	carbohydrate kinase activity
ECDH1ME8569_RS21055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECDH1ME8569_RS21060	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS21065	COG1129	ABC transporter
ECDH1ME8569_RS21070	COG1879	ABC-type sugar transport system periplasmic component
ECDH1ME8569_RS21075	COG1737	Transcriptional regulator
ECDH1ME8569_RS21080	COG0698	ribose 5-phosphate isomerase
ECDH1ME8569_RS21090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ECDH1ME8569_RS21095	COG0456	acetyltransferase
ECDH1ME8569_RS21100	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ECDH1ME8569_RS21105	COG3454	Phosphonate metabolism
ECDH1ME8569_RS21110	COG4778	phosphonate C-P lyase system protein PhnL
ECDH1ME8569_RS21115	COG4107	phosphonate C-P lyase system protein PhnK
ECDH1ME8569_RS21120	COG3627	carbon phosphorus lyase activity
ECDH1ME8569_RS21125	COG3626	phosphonate metabolism
ECDH1ME8569_RS21130	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ECDH1ME8569_RS21135	COG3624	Phosphonate C-P lyase system protein PhnG
ECDH1ME8569_RS21140	COG2188	Transcriptional regulator
ECDH1ME8569_RS21150	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ECDH1ME8569_RS21155	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ECDH1ME8569_RS21160	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ECDH1ME8569_RS21165	COG2824	Alkylphosphonate utilization operon protein PhnA
ECDH1ME8569_RS21170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ECDH1ME8569_RS21180	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS21190	COG0642	Histidine kinase
ECDH1ME8569_RS21195	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS21200	COG2194	sulfuric ester hydrolase activity
ECDH1ME8569_RS21205	COG0531	amino acid
ECDH1ME8569_RS21210	COG2207	Transcriptional regulator
ECDH1ME8569_RS21215	COG1982	Orn Lys Arg decarboxylase major
ECDH1ME8569_RS21220	COG2169	Transcriptional regulator
ECDH1ME8569_RS21230	COG1486	melibiose metabolic process
ECDH1ME8569_RS21235	COG2211	Major facilitator Superfamily
ECDH1ME8569_RS21240	COG3647	Membrane
ECDH1ME8569_RS21245	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECDH1ME8569_RS21245	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECDH1ME8569_RS21250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECDH1ME8569_RS21260	COG4565	transcriptional regulatory protein
ECDH1ME8569_RS21265	COG3290	protein histidine kinase activity
ECDH1ME8569_RS21270	COG3592	Divergent 4Fe-4S mono-cluster
ECDH1ME8569_RS21275	COG2388	GCN5-related N-acetyl-transferase
ECDH1ME8569_RS21290	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECDH1ME8569_RS21295	COG3104	oligopeptide transport
ECDH1ME8569_RS21300	COG1982	Orn Lys Arg decarboxylase major
ECDH1ME8569_RS21305	COG0531	amino acid
ECDH1ME8569_RS21315	COG3710	Transcriptional regulator
ECDH1ME8569_RS21325	COG1309	transcriptional regulator
ECDH1ME8569_RS21330	COG4232	protein-disulfide reductase activity
ECDH1ME8569_RS21340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECDH1ME8569_RS21345	COG1027	Aspartate ammonia-lyase
ECDH1ME8569_RS21350	COG3030	protein affecting phage T7 exclusion by the F plasmid
ECDH1ME8569_RS21355	COG0531	amino acid
ECDH1ME8569_RS21380	COG1509	lysine 2,3-aminomutase activity
ECDH1ME8569_RS21390	COG5510	response to toxic substance
ECDH1ME8569_RS21395	COG5510	response to toxic substance
ECDH1ME8569_RS21400	COG2076	Multidrug Resistance protein
ECDH1ME8569_RS21405	COG3040	lipid binding
ECDH1ME8569_RS21410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECDH1ME8569_RS21425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECDH1ME8569_RS21430	COG1053	succinate dehydrogenase
ECDH1ME8569_RS21440	COG0531	amino acid
ECDH1ME8569_RS21455	COG3264	Mechanosensitive ion channel
ECDH1ME8569_RS21455	COG1511	domain protein
ECDH1ME8569_RS21490	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ECDH1ME8569_RS21495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ECDH1ME8569_RS21495	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECDH1ME8569_RS21500	COG0802	atpase or kinase
ECDH1ME8569_RS21505	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECDH1ME8569_RS21525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ECDH1ME8569_RS21530	COG0330	HflC and HflK could
ECDH1ME8569_RS21535	COG0330	HflC and HflK could
ECDH1ME8569_RS21540	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ECDH1ME8569_RS21555	COG0557	exoribonuclease II activity
ECDH1ME8569_RS21560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECDH1ME8569_RS21565	COG3789	protein conserved in bacteria
ECDH1ME8569_RS21570	COG1842	Phage shock protein A
ECDH1ME8569_RS21580	COG3766	membrane
ECDH1ME8569_RS21585	COG5463	Belongs to the UPF0441 family
ECDH1ME8569_RS21590	COG0754	glutathionylspermidine amidase activity
ECDH1ME8569_RS21595	COG1960	acyl-CoA dehydrogenase activity
ECDH1ME8569_RS21605	COG3650	response to hydrogen peroxide
ECDH1ME8569_RS21610	COG1073	alpha beta
ECDH1ME8569_RS21625	COG3037	sugar-specific permease SgaT UlaA
ECDH1ME8569_RS21630	COG3414	Phosphotransferase system galactitol-specific IIB component
ECDH1ME8569_RS21635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS21675	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ECDH1ME8569_RS21690	COG1309	transcriptional regulator
ECDH1ME8569_RS21695	COG3061	Opacity-associated protein A
ECDH1ME8569_RS21700	COG0545	Peptidyl-prolyl cis-trans isomerase
ECDH1ME8569_RS21705	COG1113	amino acid transport
ECDH1ME8569_RS21715	COG0697	spore germination
ECDH1ME8569_RS21720	COG0702	epimerase
ECDH1ME8569_RS21725	COG1733	regulation of RNA biosynthetic process
ECDH1ME8569_RS21740	COG1218	3'(2'),5'-bisphosphate nucleotidase
ECDH1ME8569_RS21750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECDH1ME8569_RS21760	COG1253	flavin adenine dinucleotide binding
ECDH1ME8569_RS21775	COG0729	surface antigen
ECDH1ME8569_RS21780	COG2911	Protein conserved in bacteria
ECDH1ME8569_RS21785	COG2105	PFAM AIG2 family protein
ECDH1ME8569_RS21790	COG2336	PFAM SpoVT AbrB
ECDH1ME8569_RS21795	COG2337	Toxic component of a toxin-antitoxin (TA) module
ECDH1ME8569_RS21800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ECDH1ME8569_RS21805	COG1879	ABC-type sugar transport system periplasmic component
ECDH1ME8569_RS21810	COG1129	ABC transporter
ECDH1ME8569_RS21815	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS21820	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECDH1ME8569_RS21830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECDH1ME8569_RS21840	COG0312	modulator of DNA gyrase
ECDH1ME8569_RS21845	COG3783	Cytochrome b(562)
ECDH1ME8569_RS21850	COG0602	queuosine metabolic process
ECDH1ME8569_RS21855	COG1328	CTP reductase activity
ECDH1ME8569_RS21860	COG0366	Alpha amylase catalytic
ECDH1ME8569_RS21865	COG1263	PTS System
ECDH1ME8569_RS21865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECDH1ME8569_RS21870	COG1609	Transcriptional regulator
ECDH1ME8569_RS21875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ECDH1ME8569_RS21880	COG0251	oxidation-reduction process
ECDH1ME8569_RS21905	COG0251	oxidation-reduction process
ECDH1ME8569_RS21910	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS21915	COG1309	transcriptional regulator
ECDH1ME8569_RS21920	COG2731	YhcH YjgK YiaL family protein
ECDH1ME8569_RS21930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECDH1ME8569_RS21935	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ECDH1ME8569_RS21940	COG0456	acetyltransferase
ECDH1ME8569_RS21945	COG4269	membrane
ECDH1ME8569_RS21950	COG0525	valine-tRNA ligase activity
ECDH1ME8569_RS21955	COG2927	DNA polymerase III (CHI subunit)
ECDH1ME8569_RS21965	COG0795	lipopolysaccharide-transporting ATPase activity
ECDH1ME8569_RS21970	COG0795	lipopolysaccharide-transporting ATPase activity
ECDH1ME8569_RS21975	COG0433	COG0433 Predicted ATPase
ECDH1ME8569_RS21980	COG1609	Transcriptional regulator
ECDH1ME8569_RS21985	COG2610	gluconate transmembrane transporter activity
ECDH1ME8569_RS21990	COG1028	Short-chain dehydrogenase reductase Sdr
ECDH1ME8569_RS21995	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS22000	COG3265	gluconokinase activity
ECDH1ME8569_RS22005	COG1064	alcohol dehydrogenase
ECDH1ME8569_RS22015	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS22055	COG3385	transposase activity
ECDH1ME8569_RS22060	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS22065	COG0673	inositol 2-dehydrogenase activity
ECDH1ME8569_RS22085	COG2826	transposase and inactivated derivatives, IS30 family
ECDH1ME8569_RS22100	COG2085	NADP oxidoreductase coenzyme F420-dependent
ECDH1ME8569_RS22105	COG1120	ATPase activity
ECDH1ME8569_RS22110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECDH1ME8569_RS22115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECDH1ME8569_RS22120	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ECDH1ME8569_RS22125	COG4772	TonB-dependent receptor
ECDH1ME8569_RS22130	COG3712	iron ion homeostasis
ECDH1ME8569_RS22135	COG1595	DNA-templated transcription, initiation
ECDH1ME8569_RS22155	COG2390	Transcriptional regulator
ECDH1ME8569_RS22165	COG2610	gluconate transmembrane transporter activity
ECDH1ME8569_RS22170	COG0129	dihydroxy-acid dehydratase activity
ECDH1ME8569_RS22175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECDH1ME8569_RS22180	COG1414	Transcriptional regulator
ECDH1ME8569_RS22185	COG1349	DNA-binding transcription factor activity
ECDH1ME8569_RS22190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECDH1ME8569_RS22195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECDH1ME8569_RS22200	COG0434	BtpA family
ECDH1ME8569_RS22205	COG3775	system Galactitol-specific IIC component
ECDH1ME8569_RS22210	COG3414	Phosphotransferase system galactitol-specific IIB component
ECDH1ME8569_RS22215	COG1363	Peptidase, m42
ECDH1ME8569_RS22220	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ECDH1ME8569_RS22225	COG3153	acetyltransferase
ECDH1ME8569_RS22245	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ECDH1ME8569_RS22245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECDH1ME8569_RS22255	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ECDH1ME8569_RS22260	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECDH1ME8569_RS22275	COG0582	viral genome integration into host DNA
ECDH1ME8569_RS22280	COG4974	Belongs to the 'phage' integrase family
ECDH1ME8569_RS22290	COG3539	Fimbrial protein
ECDH1ME8569_RS22295	COG3539	Fimbrial protein
ECDH1ME8569_RS22300	COG3121	Chaperone
ECDH1ME8569_RS22305	COG3188	usher protein
ECDH1ME8569_RS22310	COG3539	Fimbrial protein
ECDH1ME8569_RS22315	COG3539	Fimbrial protein
ECDH1ME8569_RS22320	COG3539	Fimbrial protein
ECDH1ME8569_RS22325	COG2610	gluconate transmembrane transporter activity
ECDH1ME8569_RS22340	COG0246	Mannitol dehydrogenase
ECDH1ME8569_RS22350	COG2186	Transcriptional regulator
ECDH1ME8569_RS22380	COG0583	DNA-binding transcription factor activity
ECDH1ME8569_RS22385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECDH1ME8569_RS22390	COG0700	Nucleoside recognition
ECDH1ME8569_RS22395	COG3366	ferrous iron transmembrane transporter activity
ECDH1ME8569_RS22405	COG0477	Major facilitator Superfamily
ECDH1ME8569_RS22410	COG3204	pilus organization
ECDH1ME8569_RS22420	COG1924	4 iron, 4 sulfur cluster binding
ECDH1ME8569_RS22425	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ECDH1ME8569_RS22430	COG2733	membrane
ECDH1ME8569_RS22435	COG2814	Major facilitator Superfamily
ECDH1ME8569_RS22445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECDH1ME8569_RS22450	COG5457	Domain of unknown function (DUF1127)
ECDH1ME8569_RS22455	COG1196	nuclear chromosome segregation
ECDH1ME8569_RS22465	COG4268	DNA restriction-modification system
ECDH1ME8569_RS22470	COG1401	restriction endodeoxyribonuclease activity
ECDH1ME8569_RS22480	COG0732	type I restriction modification DNA specificity domain
ECDH1ME8569_RS22485	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ECDH1ME8569_RS22495	COG1715	Restriction endonuclease
ECDH1ME8569_RS22500	COG0523	cobalamin synthesis protein
ECDH1ME8569_RS22505	COG2879	small protein
ECDH1ME8569_RS22510	COG1966	Carbon starvation protein
ECDH1ME8569_RS22520	COG0840	transmembrane signaling receptor activity
ECDH1ME8569_RS22525	COG2271	Major facilitator Superfamily
ECDH1ME8569_RS22530	COG1802	Transcriptional regulator
ECDH1ME8569_RS22535	COG1063	alcohol dehydrogenase
ECDH1ME8569_RS22550	COG1484	DNA-dependent DNA replication
ECDH1ME8569_RS22565	COG2966	Psort location CytoplasmicMembrane, score
ECDH1ME8569_RS22570	COG2197	response regulator
ECDH1ME8569_RS22575	COG2197	response regulator
ECDH1ME8569_RS22580	COG4114	ferric iron reductase
ECDH1ME8569_RS22610	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ECDH1ME8569_RS22615	COG0456	acetyltransferase
ECDH1ME8569_RS22620	COG1011	Hydrolase
ECDH1ME8569_RS22630	COG2823	Periplasmic or secreted lipoprotein
ECDH1ME8569_RS22640	COG4667	esterase of the alpha-beta hydrolase superfamily
ECDH1ME8569_RS22645	COG0084	hydrolase, TatD family'
ECDH1ME8569_RS22650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECDH1ME8569_RS22655	COG1328	CTP reductase activity
ECDH1ME8569_RS22685	COG3550	peptidyl-serine autophosphorylation
ECDH1ME8569_RS22695	COG3726	membrane protein affecting hemolysin expression
ECDH1ME8569_RS22700	COG0560	Phosphoserine phosphatase
ECDH1ME8569_RS22705	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECDH1ME8569_RS22710	COG3172	ATPase kinase involved in NAD metabolism
ECDH1ME8569_RS22710	COG1056	cytidyltransferase-related domain
ECDH1ME8569_RS22720	COG0488	(ABC) transporter
ECDH1ME8569_RS22725	COG0741	lytic transglycosylase activity
ECDH1ME8569_RS22745	COG2207	Transcriptional regulator
ECDH1ME8569_RS22745	COG3708	Transcriptional regulator
ECDH1ME8569_RS22750	COG3045	CreA protein
ECDH1ME8569_RS22755	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS22760	COG2205	protein histidine kinase activity
ECDH1ME8569_RS22765	COG4452	Inner membrane protein CreD
ECDH1ME8569_RS22770	COG0745	RESPONSE REGULATOR receiver
ECDH1ME8569_RS22780	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA