locus-tag	class	description
ADZ28_RS00010	COG0527	aspartate kinase activity
ADZ28_RS00010	COG0460	homoserine dehydrogenase
ADZ28_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADZ28_RS00040	COG1115	amino acid carrier protein
ADZ28_RS00045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADZ28_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADZ28_RS00055	COG1584	GPR1 FUN34 yaaH family protein
ADZ28_RS00060	COG4735	regulation of single-species biofilm formation
ADZ28_RS00080	COG3385	transposase activity
ADZ28_RS00090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADZ28_RS00095	COG0583	DNA-binding transcription factor activity
ADZ28_RS00120	COG0196	riboflavin kinase activity
ADZ28_RS00135	COG1047	Peptidyl-prolyl cis-trans
ADZ28_RS00165	COG0505	Belongs to the CarA family
ADZ28_RS00170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADZ28_RS00225	COG0644	oxidoreductase
ADZ28_RS00230	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ADZ28_RS00235	COG2271	Major facilitator Superfamily
ADZ28_RS00250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ADZ28_RS00275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADZ28_RS00280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADZ28_RS00285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADZ28_RS00295	COG0564	pseudouridine synthase activity
ADZ28_RS00305	COG0417	DNA replication proofreading
ADZ28_RS00310	COG0235	Class ii aldolase
ADZ28_RS00315	COG2160	L-arabinose isomerase activity
ADZ28_RS00320	COG1069	ribulokinase activity
ADZ28_RS00325	COG4977	sequence-specific DNA binding
ADZ28_RS00330	COG0586	Pfam SNARE associated Golgi protein
ADZ28_RS00335	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ADZ28_RS00340	COG1178	ABC-type Fe3 transport system permease component
ADZ28_RS00345	COG4143	(ABC) transporter
ADZ28_RS00360	COG2814	Major facilitator Superfamily
ADZ28_RS00375	COG0473	3-isopropylmalate dehydrogenase activity
ADZ28_RS00390	COG0583	DNA-binding transcription factor activity
ADZ28_RS00395	COG0028	Belongs to the TPP enzyme family
ADZ28_RS00400	COG0440	acetolactate synthase activity
ADZ28_RS00410	COG1609	Transcriptional regulator
ADZ28_RS00415	COG2001	Belongs to the MraZ family
ADZ28_RS00425	COG3116	cell division
ADZ28_RS00430	COG0768	penicillin binding
ADZ28_RS00435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADZ28_RS00440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ADZ28_RS00450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADZ28_RS00455	COG0772	Belongs to the SEDS family
ADZ28_RS00470	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADZ28_RS00475	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ADZ28_RS00480	COG0849	cell division
ADZ28_RS00485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADZ28_RS00505	COG0494	nUDIX hydrolase
ADZ28_RS00525	COG0237	dephospho-CoA kinase activity
ADZ28_RS00535	COG1459	type II secretion system
ADZ28_RS00540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ADZ28_RS00545	COG4969	Belongs to the N-Me-Phe pilin family
ADZ28_RS00555	COG0157	Belongs to the NadC ModD family
ADZ28_RS00560	COG3023	N-Acetylmuramoyl-L-alanine amidase
ADZ28_RS00565	COG3725	Membrane protein required for beta-lactamase induction
ADZ28_RS00570	COG1113	amino acid transport
ADZ28_RS00575	COG2186	Transcriptional regulator
ADZ28_RS00580	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADZ28_RS00585	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADZ28_RS00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADZ28_RS00595	COG3064	Membrane
ADZ28_RS00600	COG1049	propionate catabolic process, 2-methylcitrate cycle
ADZ28_RS00625	COG2132	Multicopper oxidase
ADZ28_RS00630	COG4993	Dehydrogenase
ADZ28_RS00635	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ADZ28_RS00640	COG0288	reversible hydration of carbon dioxide
ADZ28_RS00645	COG1131	(ABC) transporter
ADZ28_RS00650	COG0842	Transport permease protein
ADZ28_RS00655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS00660	COG0726	polysaccharide deacetylase
ADZ28_RS00670	COG5464	transposase or invertase
ADZ28_RS00685	COG3539	Fimbrial protein
ADZ28_RS00690	COG3539	Fimbrial protein
ADZ28_RS00695	COG3539	Fimbrial protein
ADZ28_RS00700	COG3539	Fimbrial protein
ADZ28_RS00705	COG3188	usher protein
ADZ28_RS00710	COG3121	Chaperone
ADZ28_RS00715	COG3539	Fimbrial protein
ADZ28_RS00720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADZ28_RS00725	COG0617	tRNA 3'-terminal CCA addition
ADZ28_RS00735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ADZ28_RS00745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ADZ28_RS00750	COG1643	Atp-dependent helicase
ADZ28_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADZ28_RS00765	COG4774	siderophore transport
ADZ28_RS00770	COG1120	ATPase activity
ADZ28_RS00775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADZ28_RS00780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADZ28_RS00800	COG2860	membrane
ADZ28_RS00805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADZ28_RS00820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADZ28_RS00825	COG3835	regulator
ADZ28_RS00835	COG1408	metallophosphoesterase
ADZ28_RS00850	COG0024	Methionine aminopeptidase
ADZ28_RS00875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADZ28_RS00880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADZ28_RS00885	COG0575	Belongs to the CDS family
ADZ28_RS00890	COG0750	zinc metalloprotease
ADZ28_RS00900	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ADZ28_RS00905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADZ28_RS00930	COG0587	DNA-directed DNA polymerase activity
ADZ28_RS00940	COG1982	Orn Lys Arg decarboxylase major
ADZ28_RS00945	COG0346	lactoylglutathione lyase activity
ADZ28_RS00950	COG0037	tRNA processing
ADZ28_RS00955	COG4568	rho-dependent transcription termination
ADZ28_RS00965	COG4681	YaeQ
ADZ28_RS00970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADZ28_RS00975	COG3015	lipoprotein NlpE involved in copper resistance
ADZ28_RS00980	COG0791	NLP P60 protein
ADZ28_RS00990	COG1720	tRNA m6t6A37 methyltransferase activity
ADZ28_RS01000	COG1464	Belongs to the NlpA lipoprotein family
ADZ28_RS01005	COG2011	ABC-type metal ion transport system permease component
ADZ28_RS01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ADZ28_RS01015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADZ28_RS01050	COG0656	L-ascorbic acid biosynthetic process
ADZ28_RS01055	COG0583	DNA-binding transcription factor activity
ADZ28_RS01065	COG2226	methyltransferase
ADZ28_RS01070	COG1388	LysM domain
ADZ28_RS01070	COG0741	lytic transglycosylase activity
ADZ28_RS01080	COG2226	methyltransferase
ADZ28_RS01090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADZ28_RS01110	COG4104	PAAR repeat-containing protein
ADZ28_RS01115	COG5433	transposase activity
ADZ28_RS01120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADZ28_RS01130	COG1960	acyl-CoA dehydrogenase activity
ADZ28_RS01140	COG0121	glutamine amidotransferase
ADZ28_RS01145	COG3034	peptidoglycan biosynthetic process
ADZ28_RS01150	COG3041	Addiction module toxin RelE StbE family
ADZ28_RS01155	COG3077	Addiction module antitoxin, RelB DinJ family
ADZ28_RS01160	COG0791	NLP P60 protein
ADZ28_RS01165	COG1943	Transposase
ADZ28_RS01185	COG2161	toxin-antitoxin pair type II binding
ADZ28_RS01195	COG0454	-acetyltransferase
ADZ28_RS01200	COG1690	Belongs to the RtcB family
ADZ28_RS01205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADZ28_RS01210	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADZ28_RS01230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADZ28_RS01260	COG2003	Belongs to the UPF0758 family
ADZ28_RS01280	COG2378	regulation of single-species biofilm formation
ADZ28_RS01295	COG3596	GTP binding
ADZ28_RS01300	COG0583	DNA-binding transcription factor activity
ADZ28_RS01305	COG2963	transposase activity
ADZ28_RS01310	COG2826	transposase and inactivated derivatives, IS30 family
ADZ28_RS01315	COG2801	Transposase and inactivated derivatives
ADZ28_RS01330	COG3344	reverse transcriptase
ADZ28_RS01340	COG0833	amino acid
ADZ28_RS01345	COG2040	homocysteine
ADZ28_RS01350	COG3842	ATPase activity
ADZ28_RS01355	COG1178	ABC-type Fe3 transport system permease component
ADZ28_RS01360	COG1662	PFAM IS1 transposase
ADZ28_RS01365	COG1662	PFAM IS1 transposase
ADZ28_RS01365	COG3677	Transposase
ADZ28_RS01370	COG2963	transposase activity
ADZ28_RS01380	COG2801	Transposase and inactivated derivatives
ADZ28_RS01380	COG3415	Transposase
ADZ28_RS01385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADZ28_RS01390	COG0129	dihydroxy-acid dehydratase activity
ADZ28_RS01395	COG2211	Major facilitator Superfamily
ADZ28_RS01400	COG3507	Belongs to the glycosyl hydrolase 43 family
ADZ28_RS01405	COG1414	Transcriptional regulator
ADZ28_RS01410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADZ28_RS01415	COG1662	PFAM IS1 transposase
ADZ28_RS01420	COG1061	Type III restriction enzyme res subunit
ADZ28_RS01430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ADZ28_RS01450	COG0582	viral genome integration into host DNA
ADZ28_RS01460	COG0583	DNA-binding transcription factor activity
ADZ28_RS01465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ADZ28_RS01470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ADZ28_RS01475	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ADZ28_RS01480	COG2080	2 iron, 2 sulfur cluster binding
ADZ28_RS01485	COG3477	response to acidic pH
ADZ28_RS01490	COG0727	PFAM Uncharacterised protein family (UPF0153)
ADZ28_RS01495	COG3121	Chaperone
ADZ28_RS01505	COG3188	usher protein
ADZ28_RS01545	COG1388	LysM domain
ADZ28_RS01555	COG2801	Transposase and inactivated derivatives
ADZ28_RS01560	COG2207	Transcriptional regulator
ADZ28_RS01560	COG3708	Transcriptional regulator
ADZ28_RS01565	COG3059	membrane
ADZ28_RS01575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADZ28_RS01580	COG2207	Transcriptional regulator
ADZ28_RS01585	COG0247	lactate metabolic process
ADZ28_RS01590	COG1139	Iron-sulfur cluster binding protein
ADZ28_RS01595	COG1556	Lactate utilization protein
ADZ28_RS01625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADZ28_RS01635	COG2200	EAL domain
ADZ28_RS01635	COG2771	luxR family
ADZ28_RS01640	COG0583	DNA-binding transcription factor activity
ADZ28_RS01650	COG0666	response to abiotic stimulus
ADZ28_RS01660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADZ28_RS01665	COG1304	FMN binding
ADZ28_RS01675	COG0549	Belongs to the carbamate kinase family
ADZ28_RS01680	COG0402	S-adenosylhomocysteine deaminase activity
ADZ28_RS01685	COG1064	alcohol dehydrogenase
ADZ28_RS01700	COG1280	lysine exporter protein (LysE YggA)
ADZ28_RS01710	COG3829	transcription factor binding
ADZ28_RS01715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ADZ28_RS01720	COG0372	Belongs to the citrate synthase family
ADZ28_RS01725	COG2079	MmgE PrpD family protein
ADZ28_RS01730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADZ28_RS01735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ADZ28_RS01740	COG0402	S-adenosylhomocysteine deaminase activity
ADZ28_RS01745	COG0583	DNA-binding transcription factor activity
ADZ28_RS01750	COG0288	reversible hydration of carbon dioxide
ADZ28_RS01760	COG2807	transmembrane transport
ADZ28_RS01765	COG0110	maltose O-acetyltransferase activity
ADZ28_RS01770	COG2223	nitrite transmembrane transporter activity
ADZ28_RS01775	COG3250	beta-galactosidase activity
ADZ28_RS01780	COG1609	Transcriptional regulator
ADZ28_RS01785	COG1414	Transcriptional regulator
ADZ28_RS01805	COG3971	2-oxopent-4-enoate hydratase activity
ADZ28_RS01820	COG2814	Major facilitator Superfamily
ADZ28_RS01825	COG3122	Protein conserved in bacteria
ADZ28_RS01835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ADZ28_RS01870	COG1215	transferase activity, transferring glycosyl groups
ADZ28_RS01875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ADZ28_RS01880	COG4521	taurine ABC transporter
ADZ28_RS01890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADZ28_RS01895	COG2175	clavaminate synthase activity
ADZ28_RS01900	COG0113	porphobilinogen synthase activity
ADZ28_RS01915	COG2801	Transposase and inactivated derivatives
ADZ28_RS01925	COG3468	outer membrane autotransporter barrel domain protein
ADZ28_RS01930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADZ28_RS01935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ADZ28_RS01945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ADZ28_RS01965	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADZ28_RS01980	COG1785	Belongs to the alkaline phosphatase family
ADZ28_RS01990	COG3706	GGDEF domain
ADZ28_RS01995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADZ28_RS02020	COG4126	flavin adenine dinucleotide binding
ADZ28_RS02040	COG1940	carbohydrate kinase activity
ADZ28_RS02045	COG2814	Major facilitator Superfamily
ADZ28_RS02050	COG0419	ATPase involved in DNA repair
ADZ28_RS02055	COG0420	3'-5' exonuclease activity
ADZ28_RS02060	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS02065	COG5002	protein histidine kinase activity
ADZ28_RS02070	COG1114	Component of the transport system for branched-chain amino acids
ADZ28_RS02075	COG1113	amino acid transport
ADZ28_RS02080	COG0366	Alpha amylase catalytic
ADZ28_RS02100	COG1862	Preprotein translocase
ADZ28_RS02105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADZ28_RS02110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADZ28_RS02115	COG1403	HNH endonuclease
ADZ28_RS02125	COG3248	Nucleoside-binding outer membrane protein
ADZ28_RS02130	COG4238	major outer membrane lipoprotein
ADZ28_RS02140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADZ28_RS02140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADZ28_RS02155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ADZ28_RS02160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ADZ28_RS02165	COG0667	Aldo Keto reductase
ADZ28_RS02175	COG0142	geranyltranstransferase activity
ADZ28_RS02190	COG0693	protein deglycase activity
ADZ28_RS02195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ADZ28_RS02205	COG2814	Major facilitator Superfamily
ADZ28_RS02215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ADZ28_RS02220	COG1845	cytochrome c oxidase, subunit III
ADZ28_RS02225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADZ28_RS02230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ADZ28_RS02235	COG2223	nitrite transmembrane transporter activity
ADZ28_RS02240	COG3056	Lipoprotein
ADZ28_RS02245	COG0271	Belongs to the BolA IbaG family
ADZ28_RS02270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADZ28_RS02275	COG0776	regulation of translation
ADZ28_RS02280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADZ28_RS02285	COG1555	photosystem II stabilization
ADZ28_RS02290	COG0824	Thioesterase
ADZ28_RS02300	COG4533	DNA binding
ADZ28_RS02310	COG1522	sequence-specific DNA binding
ADZ28_RS02315	COG1132	(ABC) transporter
ADZ28_RS02320	COG1132	(ABC) transporter
ADZ28_RS02325	COG0347	Belongs to the P(II) protein family
ADZ28_RS02330	COG0004	ammonium transporteR
ADZ28_RS02335	COG1946	Acyl-CoA thioesterase
ADZ28_RS02340	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ADZ28_RS02345	COG3695	enzyme binding
ADZ28_RS02350	COG5507	3-demethylubiquinone-9 3-methyltransferase
ADZ28_RS02355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ADZ28_RS02365	COG0110	maltose O-acetyltransferase activity
ADZ28_RS02380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADZ28_RS02385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADZ28_RS02390	COG1309	transcriptional regulator
ADZ28_RS02395	COG3264	Mechanosensitive ion channel
ADZ28_RS02395	COG1196	nuclear chromosome segregation
ADZ28_RS02410	COG3923	Primosomal replication protein n
ADZ28_RS02415	COG2832	Protein of unknown function (DUF454)
ADZ28_RS02425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADZ28_RS02460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS02465	COG4651	solute:proton antiporter activity
ADZ28_RS02465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADZ28_RS02470	COG2223	nitrite transmembrane transporter activity
ADZ28_RS02475	COG0737	Belongs to the 5'-nucleotidase family
ADZ28_RS02480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADZ28_RS02485	COG3735	TraB family
ADZ28_RS02490	COG3093	addiction module antidote protein HigA
ADZ28_RS02495	COG2217	Heavy metal translocating P-type atpase
ADZ28_RS02500	COG2066	Belongs to the glutaminase family
ADZ28_RS02505	COG0531	amino acid
ADZ28_RS02510	COG0789	Transcriptional regulator
ADZ28_RS02515	COG1585	Membrane protein implicated in regulation of membrane protease activity
ADZ28_RS02520	COG0330	HflC and HflK could
ADZ28_RS02525	COG4619	ABC transporter
ADZ28_RS02530	COG0390	transport system, permease component
ADZ28_RS02535	COG3118	belongs to the thioredoxin family
ADZ28_RS02540	COG0300	oxidoreductase activity
ADZ28_RS02545	COG2755	lipolytic protein G-D-S-L family
ADZ28_RS02550	COG4181	ATPase activity
ADZ28_RS02555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ADZ28_RS02560	COG3209	COG3209 Rhs family protein
ADZ28_RS02570	COG3209	COG3209 Rhs family protein
ADZ28_RS02580	COG2801	Transposase and inactivated derivatives
ADZ28_RS02590	COG0583	DNA-binding transcription factor activity
ADZ28_RS02600	COG1414	Transcriptional regulator
ADZ28_RS02605	COG3960	tartronate-semialdehyde synthase activity
ADZ28_RS02610	COG3622	Belongs to the hyi family
ADZ28_RS02615	COG2084	Dehydrogenase
ADZ28_RS02620	COG1953	Uracil, thiamine, allantoin
ADZ28_RS02630	COG2233	PERMEase
ADZ28_RS02635	COG1929	Belongs to the glycerate kinase type-1 family
ADZ28_RS02640	COG3257	ureidoglycine aminohydrolase activity
ADZ28_RS02645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADZ28_RS02650	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADZ28_RS02655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADZ28_RS02660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADZ28_RS02670	COG0549	Belongs to the carbamate kinase family
ADZ28_RS02675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ADZ28_RS02680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADZ28_RS02690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADZ28_RS02700	COG1988	membrane-bound metal-dependent
ADZ28_RS02705	COG2501	S4 domain
ADZ28_RS02715	COG3539	Fimbrial protein
ADZ28_RS02720	COG3121	Chaperone
ADZ28_RS02725	COG3188	usher protein
ADZ28_RS02730	COG3539	Fimbrial protein
ADZ28_RS02735	COG3539	Fimbrial protein
ADZ28_RS02740	COG2197	response regulator
ADZ28_RS02750	COG0582	viral genome integration into host DNA
ADZ28_RS02770	COG3772	lysozyme
ADZ28_RS02790	COG5562	phage envelope protein
ADZ28_RS02810	COG4220	transposase activity
ADZ28_RS02820	COG0500	methyltransferase
ADZ28_RS02830	COG2207	Transcriptional regulator
ADZ28_RS02835	COG4571	Outer membrane protease
ADZ28_RS02845	COG2207	Transcriptional regulator
ADZ28_RS02855	COG4783	chaperone-mediated protein folding
ADZ28_RS02860	COG1215	transferase activity, transferring glycosyl groups
ADZ28_RS02865	COG5002	protein histidine kinase activity
ADZ28_RS02870	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS02875	COG1538	Outer membrane efflux protein
ADZ28_RS02880	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADZ28_RS02885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADZ28_RS02890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADZ28_RS02895	COG1113	amino acid transport
ADZ28_RS02900	COG0668	transmembrane transport
ADZ28_RS02905	COG0778	Nitroreductase
ADZ28_RS02910	COG2315	Protein conserved in bacteria
ADZ28_RS02935	COG3385	transposase activity
ADZ28_RS02940	COG2977	Belongs to the P-Pant transferase superfamily
ADZ28_RS02945	COG4771	TonB-dependent receptor
ADZ28_RS02950	COG2382	esterase
ADZ28_RS02955	COG3251	PFAM MbtH domain protein
ADZ28_RS02960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADZ28_RS02960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ADZ28_RS02965	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ADZ28_RS02970	COG1120	ATPase activity
ADZ28_RS02975	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADZ28_RS02980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADZ28_RS02990	COG4592	Periplasmic binding protein
ADZ28_RS02995	COG1169	isochorismate synthase
ADZ28_RS03000	COG1021	2,3-dihydroxybenzoate-AMP ligase
ADZ28_RS03005	COG1535	isochorismatase
ADZ28_RS03005	COG3433	isochorismatase activity
ADZ28_RS03010	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS03015	COG2050	protein possibly involved in aromatic compounds catabolism
ADZ28_RS03020	COG1966	Carbon starvation protein
ADZ28_RS03025	COG2879	small protein
ADZ28_RS03030	COG0371	Dehydrogenase
ADZ28_RS03035	COG0436	Aminotransferase
ADZ28_RS03040	COG1475	DNA binding
ADZ28_RS03045	COG3969	phosphoadenosine phosphosulfate
ADZ28_RS03050	COG0583	DNA-binding transcription factor activity
ADZ28_RS03055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADZ28_RS03060	COG0450	alkyl hydroperoxide reductase
ADZ28_RS03065	COG3634	alkyl hydroperoxide reductase activity
ADZ28_RS03070	COG0589	response to stress
ADZ28_RS03075	COG1063	alcohol dehydrogenase
ADZ28_RS03085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADZ28_RS03090	COG3719	Belongs to the RNase T2 family
ADZ28_RS03095	COG0471	metal ion transport
ADZ28_RS03110	COG3051	citrate lyase alpha subunit
ADZ28_RS03115	COG2301	Belongs to the HpcH HpaI aldolase family
ADZ28_RS03125	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ADZ28_RS03130	COG3290	protein histidine kinase activity
ADZ28_RS03135	COG4565	transcriptional regulatory protein
ADZ28_RS03140	COG3069	C4-dicarboxylate transmembrane transporter activity
ADZ28_RS03165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADZ28_RS03175	COG0583	DNA-binding transcription factor activity
ADZ28_RS03195	COG1686	Belongs to the peptidase S11 family
ADZ28_RS03200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADZ28_RS03205	COG0772	Belongs to the SEDS family
ADZ28_RS03210	COG0768	penicillin binding
ADZ28_RS03220	COG0799	negative regulation of ribosome biogenesis
ADZ28_RS03225	COG0406	alpha-ribazole phosphatase activity
ADZ28_RS03235	COG1466	dna polymerase III delta subunit
ADZ28_RS03250	COG2888	peptidyl-tyrosine sulfation
ADZ28_RS03255	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ADZ28_RS03265	COG2214	Heat shock protein DnaJ domain protein
ADZ28_RS03270	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ADZ28_RS03280	COG2214	Heat shock protein DnaJ domain protein
ADZ28_RS03285	COG0443	Heat shock 70 kDa protein
ADZ28_RS03295	COG1126	abc transporter atp-binding protein
ADZ28_RS03300	COG0765	amino acid transport
ADZ28_RS03305	COG0765	amino acid transport
ADZ28_RS03310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS03320	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ADZ28_RS03325	COG4535	Mg2 and Co2 transporter CorC
ADZ28_RS03335	COG1702	phosphate starvation-inducible protein PhoH
ADZ28_RS03345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADZ28_RS03385	COG0367	asparagine synthase
ADZ28_RS03390	COG0647	UMP catabolic process
ADZ28_RS03395	COG1940	carbohydrate kinase activity
ADZ28_RS03395	COG1846	Transcriptional regulator
ADZ28_RS03400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ADZ28_RS03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS03410	COG1263	PTS System
ADZ28_RS03410	COG2190	(PTS) system
ADZ28_RS03430	COG0735	belongs to the Fur family
ADZ28_RS03445	COG0716	FMN binding
ADZ28_RS03455	COG0596	Alpha beta hydrolase
ADZ28_RS03460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ADZ28_RS03465	COG0033	Phosphoglucomutase
ADZ28_RS03485	COG0531	amino acid
ADZ28_RS03490	COG1982	Orn Lys Arg decarboxylase major
ADZ28_RS03500	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS03505	COG2205	protein histidine kinase activity
ADZ28_RS03535	COG3209	COG3209 Rhs family protein
ADZ28_RS03545	COG3209	COG3209 Rhs family protein
ADZ28_RS03555	COG5433	transposase activity
ADZ28_RS03565	COG3272	Protein of unknown function (DUF1722)
ADZ28_RS03570	COG0415	Belongs to the DNA photolyase family
ADZ28_RS03575	COG3104	oligopeptide transport
ADZ28_RS03580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADZ28_RS03585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ADZ28_RS03590	COG1984	allophanate hydrolase subunit 2
ADZ28_RS03605	COG3180	Ammonia monooxygenase
ADZ28_RS03610	COG3539	Fimbrial protein
ADZ28_RS03615	COG3121	Chaperone
ADZ28_RS03620	COG3188	usher protein
ADZ28_RS03625	COG3539	Fimbrial protein
ADZ28_RS03630	COG0372	Belongs to the citrate synthase family
ADZ28_RS03640	COG2009	succinate dehydrogenase
ADZ28_RS03645	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ADZ28_RS03650	COG1053	succinate dehydrogenase
ADZ28_RS03655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADZ28_RS03665	COG0567	Dehydrogenase, E1 component
ADZ28_RS03670	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADZ28_RS03680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ADZ28_RS03685	COG2188	Transcriptional regulator
ADZ28_RS03690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS03690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS03690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS03695	COG0383	alpha-mannosidase activity
ADZ28_RS03705	COG1271	oxidase subunit
ADZ28_RS03710	COG1294	oxidase, subunit
ADZ28_RS03715	COG4890	Cyd operon protein YbgT
ADZ28_RS03720	COG3790	cyd operon protein YbgE
ADZ28_RS03725	COG0824	Thioesterase
ADZ28_RS03730	COG0811	peptide transport
ADZ28_RS03735	COG0848	biopolymer transport protein
ADZ28_RS03740	COG3064	Membrane
ADZ28_RS03750	COG2885	chlorophyll binding
ADZ28_RS03755	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ADZ28_RS03800	COG3201	nicotinamide mononucleotide transporter
ADZ28_RS03805	COG1230	cation diffusion facilitator family transporter
ADZ28_RS03820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ADZ28_RS03830	COG2017	converts alpha-aldose to the beta-anomer
ADZ28_RS03840	COG1085	galactose-1-phosphate uridylyltransferase
ADZ28_RS03845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADZ28_RS03850	COG1119	ATPase activity
ADZ28_RS03855	COG3585	molybdate ion transport
ADZ28_RS03855	COG2005	Transcriptional regulator
ADZ28_RS03865	COG0725	ABC transporter, periplasmic molybdate-binding protein
ADZ28_RS03870	COG4149	molybdate abc transporter
ADZ28_RS03875	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ADZ28_RS03880	COG0561	phosphatase activity
ADZ28_RS03890	COG0583	DNA-binding transcription factor activity
ADZ28_RS03895	COG2828	Protein conserved in bacteria
ADZ28_RS03900	COG0471	metal ion transport
ADZ28_RS03905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADZ28_RS03910	COG4677	pectinesterase activity
ADZ28_RS03915	COG1881	PFAM PEBP family protein
ADZ28_RS03920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ADZ28_RS03935	COG2226	methyltransferase
ADZ28_RS03940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADZ28_RS03950	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ADZ28_RS03965	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADZ28_RS03975	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ADZ28_RS03980	COG0314	molybdopterin synthase activity
ADZ28_RS03985	COG0670	Belongs to the BI1 family
ADZ28_RS03990	COG0670	Belongs to the BI1 family
ADZ28_RS03995	COG0392	lysyltransferase activity
ADZ28_RS04000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADZ28_RS04005	COG3568	Endonuclease Exonuclease Phosphatase
ADZ28_RS04015	COG0842	Transport permease protein
ADZ28_RS04020	COG0842	Transport permease protein
ADZ28_RS04025	COG1131	(ABC) transporter
ADZ28_RS04035	COG1309	transcriptional regulator
ADZ28_RS04040	COG0513	Belongs to the DEAD box helicase family
ADZ28_RS04045	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ADZ28_RS04050	COG1199	ATP-dependent helicase activity
ADZ28_RS04055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADZ28_RS04060	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADZ28_RS04070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ADZ28_RS04080	COG4774	siderophore transport
ADZ28_RS04095	COG0668	transmembrane transport
ADZ28_RS04100	COG1126	abc transporter atp-binding protein
ADZ28_RS04105	COG0765	amino acid transport
ADZ28_RS04110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS04125	COG5006	permease, DMT superfamily
ADZ28_RS04130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ADZ28_RS04135	COG2194	sulfuric ester hydrolase activity
ADZ28_RS04145	COG1321	iron dependent repressor
ADZ28_RS04150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADZ28_RS04155	COG1376	ErfK ybiS ycfS ynhG family protein
ADZ28_RS04160	COG0488	(ABC) transporter
ADZ28_RS04170	COG0561	phosphatase activity
ADZ28_RS04175	COG1882	Formate acetyltransferase
ADZ28_RS04180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ADZ28_RS04185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADZ28_RS04190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADZ28_RS04195	COG0303	'Molybdopterin
ADZ28_RS04200	COG1446	asparaginase
ADZ28_RS04205	COG4172	Belongs to the ABC transporter superfamily
ADZ28_RS04210	COG0747	negative chemotaxis
ADZ28_RS04220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADZ28_RS04225	COG2200	EAL domain
ADZ28_RS04230	COG2199	diguanylate cyclase activity
ADZ28_RS04245	COG2133	pyrroloquinoline quinone binding
ADZ28_RS04250	COG0625	glutathione transferase activity
ADZ28_RS04255	COG1686	Belongs to the peptidase S11 family
ADZ28_RS04260	COG1349	DNA-binding transcription factor activity
ADZ28_RS04265	COG0671	phosphoesterase, PA-phosphatase related
ADZ28_RS04270	COG2814	Major facilitator Superfamily
ADZ28_RS04280	COG0561	phosphatase activity
ADZ28_RS04285	COG0738	Major facilitator superfamily
ADZ28_RS04290	COG3226	Transcriptional regulator
ADZ28_RS04305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADZ28_RS04315	COG0778	Nitroreductase
ADZ28_RS04335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADZ28_RS04340	COG3842	ATPase activity
ADZ28_RS04345	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADZ28_RS04350	COG1177	transmembrane transport
ADZ28_RS04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS04370	COG4160	amino acid transport
ADZ28_RS04375	COG4215	(ABC) transporter
ADZ28_RS04380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS04385	COG1126	abc transporter atp-binding protein
ADZ28_RS04400	COG3023	N-Acetylmuramoyl-L-alanine amidase
ADZ28_RS04405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADZ28_RS04410	COG0702	epimerase
ADZ28_RS04415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ADZ28_RS04420	COG0028	Belongs to the TPP enzyme family
ADZ28_RS04425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADZ28_RS04435	COG2431	L-lysine efflux transmembrane transporter activity
ADZ28_RS04450	COG3593	DNA synthesis involved in DNA repair
ADZ28_RS04455	COG2990	Protein conserved in bacteria
ADZ28_RS04460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADZ28_RS04465	COG1136	(ABC) transporter
ADZ28_RS04465	COG0577	efflux transmembrane transporter activity
ADZ28_RS04470	COG1278	Cold shock
ADZ28_RS04480	COG0542	response to heat
ADZ28_RS04500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ADZ28_RS04505	COG4988	ABC transporter
ADZ28_RS04510	COG0492	ferredoxin-NADP+ reductase activity
ADZ28_RS04515	COG1522	sequence-specific DNA binding
ADZ28_RS04520	COG1674	ftsk spoiiie
ADZ28_RS04520	COG1178	ABC-type Fe3 transport system permease component
ADZ28_RS04530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADZ28_RS04540	COG0243	molybdopterin cofactor binding
ADZ28_RS04545	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS04550	COG3302	dmso reductase anchor subunit
ADZ28_RS04555	COG1335	isochorismatase
ADZ28_RS04565	COG0531	amino acid
ADZ28_RS04570	COG0583	DNA-binding transcription factor activity
ADZ28_RS04575	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADZ28_RS04580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ADZ28_RS04585	COG1882	Formate acetyltransferase
ADZ28_RS04590	COG2116	formate transmembrane transporter activity
ADZ28_RS04595	COG1944	ATP diphosphatase activity
ADZ28_RS04600	COG2323	membrane
ADZ28_RS04615	COG0501	Belongs to the peptidase M48B family
ADZ28_RS04625	COG0539	negative regulation of cytoplasmic translation
ADZ28_RS04635	COG0658	competence protein
ADZ28_RS04635	COG2333	competence protein COMEC
ADZ28_RS04640	COG1132	(ABC) transporter
ADZ28_RS04645	COG1663	tetraacyldisaccharide 4'-kinase activity
ADZ28_RS04650	COG3214	Protein conserved in bacteria
ADZ28_RS04665	COG3173	Aminoglycoside phosphotransferase
ADZ28_RS04670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ADZ28_RS04675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADZ28_RS04685	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ADZ28_RS04695	COG2989	Protein conserved in bacteria
ADZ28_RS04700	COG3108	Peptidase M15
ADZ28_RS04705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADZ28_RS04710	COG1448	Aminotransferase
ADZ28_RS04735	COG0308	aminopeptidase N
ADZ28_RS04740	COG1116	anion transmembrane transporter activity
ADZ28_RS04745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADZ28_RS04755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ADZ28_RS04760	COG0431	NADPH-dependent FMN reductase
ADZ28_RS04765	COG3539	Fimbrial protein
ADZ28_RS04770	COG3121	Chaperone
ADZ28_RS04775	COG3188	usher protein
ADZ28_RS04780	COG3539	Fimbrial protein
ADZ28_RS04785	COG3539	Fimbrial protein
ADZ28_RS04790	COG3539	Fimbrial protein
ADZ28_RS04795	COG3121	Chaperone
ADZ28_RS04810	COG0633	Ferredoxin
ADZ28_RS04810	COG3217	Mosc domain protein beta barrel domain protein
ADZ28_RS04820	COG0488	(ABC) transporter
ADZ28_RS04825	COG2995	paraquat-inducible protein a
ADZ28_RS04830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADZ28_RS04830	COG3008	intermembrane lipid transfer
ADZ28_RS04835	COG3009	Protein conserved in bacteria
ADZ28_RS04840	COG3130	regulation of translation
ADZ28_RS04850	COG1067	ATP-dependent peptidase activity
ADZ28_RS04860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ADZ28_RS04860	COG2885	chlorophyll binding
ADZ28_RS04875	COG3070	regulator of competence-specific genes
ADZ28_RS04880	COG1289	transmembrane transporter activity
ADZ28_RS04885	COG3304	Inner membrane component domain
ADZ28_RS04890	COG0210	DNA helicase
ADZ28_RS04930	COG1832	CoA-binding protein
ADZ28_RS04945	COG1254	Belongs to the acylphosphatase family
ADZ28_RS04950	COG2920	part of a sulfur-relay system
ADZ28_RS04955	COG0670	Belongs to the BI1 family
ADZ28_RS04965	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADZ28_RS04970	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ADZ28_RS04975	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ADZ28_RS04980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADZ28_RS04985	COG1999	signal sequence binding
ADZ28_RS04990	COG1773	rubredoxin
ADZ28_RS04995	COG1271	oxidase subunit
ADZ28_RS05000	COG1294	oxidase, subunit
ADZ28_RS05015	COG0489	protein tyrosine kinase activity
ADZ28_RS05015	COG3206	protein involved in exopolysaccharide biosynthesis
ADZ28_RS05020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADZ28_RS05025	COG1596	polysaccharide export
ADZ28_RS05030	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADZ28_RS05055	COG1662	PFAM IS1 transposase
ADZ28_RS05060	COG1278	Cold shock
ADZ28_RS05065	COG1278	Cold shock
ADZ28_RS05080	COG0348	domain, Protein
ADZ28_RS05085	COG2198	Histidine kinase
ADZ28_RS05085	COG2205	protein histidine kinase activity
ADZ28_RS05085	COG0784	Response regulator, receiver
ADZ28_RS05090	COG1879	ABC-type sugar transport system periplasmic component
ADZ28_RS05095	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS05100	COG3005	denitrification pathway
ADZ28_RS05105	COG0243	molybdopterin cofactor binding
ADZ28_RS05110	COG3381	protein complex oligomerization
ADZ28_RS05150	COG3729	General stress protein
ADZ28_RS05155	COG2233	PERMEase
ADZ28_RS05190	COG1309	transcriptional regulator
ADZ28_RS05195	COG0506	proline dehydrogenase activity
ADZ28_RS05195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADZ28_RS05195	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADZ28_RS05205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADZ28_RS05220	COG2822	iron ion transport
ADZ28_RS05225	COG2837	iron assimilation
ADZ28_RS05235	COG1702	phosphate starvation-inducible protein PhoH
ADZ28_RS05240	COG3658	cytochrome
ADZ28_RS05245	COG1215	transferase activity, transferring glycosyl groups
ADZ28_RS05250	COG0726	polysaccharide deacetylase
ADZ28_RS05250	COG1649	PFAM Uncharacterised BCR, COG1649
ADZ28_RS05255	COG0457	Tetratricopeptide repeat
ADZ28_RS05270	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADZ28_RS05275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADZ28_RS05300	COG2943	transferase activity, transferring hexosyl groups
ADZ28_RS05305	COG5645	(Lipo)protein
ADZ28_RS05325	COG1560	Kdo2-lipid A biosynthetic process
ADZ28_RS05335	COG2353	YceI-like domain
ADZ28_RS05340	COG3038	cytochrome b561
ADZ28_RS05375	COG2999	glutathione oxidoreductase activity
ADZ28_RS05385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADZ28_RS05395	COG0673	inositol 2-dehydrogenase activity
ADZ28_RS05400	COG0728	peptidoglycan biosynthetic process
ADZ28_RS05405	COG3418	PFAM FlgN family protein
ADZ28_RS05410	COG2747	anti-sigma28 factor FlgM
ADZ28_RS05415	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ADZ28_RS05420	COG1815	bacterial-type flagellum-dependent cell motility
ADZ28_RS05425	COG1558	bacterial-type flagellum-dependent cell motility
ADZ28_RS05430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ADZ28_RS05435	COG1749	Flagellar hook protein flgE
ADZ28_RS05440	COG4787	bacterial-type flagellum-dependent cell motility
ADZ28_RS05445	COG4786	Flagellar basal body rod
ADZ28_RS05460	COG3951	Flagellar rod assembly protein muramidase FlgJ
ADZ28_RS05460	COG1705	Flagellar rod assembly protein muramidase FlgJ
ADZ28_RS05465	COG1256	bacterial-type flagellum assembly
ADZ28_RS05470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADZ28_RS05475	COG1530	ribonuclease E activity
ADZ28_RS05485	COG0564	pseudouridine synthase activity
ADZ28_RS05490	COG0424	maF-like protein
ADZ28_RS05495	COG1399	metal-binding, possibly nucleic acid-binding protein
ADZ28_RS05515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ADZ28_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS05530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADZ28_RS05535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADZ28_RS05540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADZ28_RS05550	COG0470	DNA polymerase III
ADZ28_RS05555	COG0084	hydrolase, TatD family'
ADZ28_RS05560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS05560	COG1263	PTS System
ADZ28_RS05565	COG4773	Receptor
ADZ28_RS05570	COG0537	adenosine 5'-monophosphoramidase activity
ADZ28_RS05575	COG5633	Lipoprotein
ADZ28_RS05580	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ADZ28_RS05600	COG1252	NADH dehydrogenase
ADZ28_RS05605	COG3134	Outer membrane lipoprotein
ADZ28_RS05610	COG1309	transcriptional regulator
ADZ28_RS05620	COG1376	ErfK ybiS ycfS ynhG family protein
ADZ28_RS05620	COG1388	LysM domain
ADZ28_RS05625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADZ28_RS05630	COG4763	Acyl-transferase
ADZ28_RS05635	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADZ28_RS05640	COG1136	(ABC) transporter
ADZ28_RS05645	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADZ28_RS05655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADZ28_RS05660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ADZ28_RS05670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADZ28_RS05675	COG1177	transmembrane transport
ADZ28_RS05685	COG3842	ATPase activity
ADZ28_RS05700	COG2850	peptidyl-arginine hydroxylation
ADZ28_RS05705	COG2205	protein histidine kinase activity
ADZ28_RS05710	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS05715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADZ28_RS05735	COG1187	pseudouridine synthase activity
ADZ28_RS05740	COG0538	isocitrate dehydrogenase activity
ADZ28_RS05745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADZ28_RS05765	COG2801	Transposase and inactivated derivatives
ADZ28_RS05770	COG0582	viral genome integration into host DNA
ADZ28_RS05785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADZ28_RS05790	COG4197	protein conserved in bacteria, prophage-related
ADZ28_RS05805	COG4626	Terminase
ADZ28_RS05805	COG1802	Transcriptional regulator
ADZ28_RS05815	COG4695	Portal protein
ADZ28_RS05820	COG3299	homolog of phage Mu protein gp47
ADZ28_RS05825	COG3778	Protein conserved in bacteria
ADZ28_RS05840	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADZ28_RS05850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ADZ28_RS05855	COG1403	HNH endonuclease
ADZ28_RS05870	COG5562	phage envelope protein
ADZ28_RS05875	COG0789	Transcriptional regulator
ADZ28_RS05880	COG2200	EAL domain
ADZ28_RS05905	COG2200	EAL domain
ADZ28_RS05950	COG2894	cell division
ADZ28_RS05980	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADZ28_RS05995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADZ28_RS06000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADZ28_RS06005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ADZ28_RS06020	COG2719	SpoVR family
ADZ28_RS06030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADZ28_RS06040	COG1619	proteins homologs of microcin C7 resistance protein MccF
ADZ28_RS06050	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ADZ28_RS06055	COG2261	transglycosylase associated protein
ADZ28_RS06070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS06070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADZ28_RS06070	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ADZ28_RS06075	COG1461	Dihydroxyacetone kinase
ADZ28_RS06080	COG2376	Dihydroxyacetone kinase
ADZ28_RS06085	COG3284	Transcriptional regulator
ADZ28_RS06090	COG3468	outer membrane autotransporter barrel domain protein
ADZ28_RS06100	COG0012	GTP binding
ADZ28_RS06115	COG0659	secondary active sulfate transmembrane transporter activity
ADZ28_RS06120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADZ28_RS06145	COG2890	protein-(glutamine-N5) methyltransferase activity
ADZ28_RS06150	COG3094	Invasion gene expression up-regulator, SirB
ADZ28_RS06155	COG2912	Transglutaminase-like superfamily
ADZ28_RS06180	COG0387	Pfam Sodium calcium exchanger
ADZ28_RS06185	COG4572	Cation transport regulator
ADZ28_RS06190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ADZ28_RS06195	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ADZ28_RS06200	COG4932	domain protein
ADZ28_RS06205	COG2197	response regulator
ADZ28_RS06210	COG3850	Histidine kinase
ADZ28_RS06220	COG2223	nitrite transmembrane transporter activity
ADZ28_RS06230	COG1140	nitrate reductase beta subunit
ADZ28_RS06235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ADZ28_RS06240	COG2181	nitrate reductase activity
ADZ28_RS06260	COG0788	formyltetrahydrofolate deformylase activity
ADZ28_RS06270	COG1752	Esterase of the alpha-beta hydrolase superfamily
ADZ28_RS06280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADZ28_RS06290	COG1435	thymidine kinase activity
ADZ28_RS06305	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS06305	COG1454	alcohol dehydrogenase
ADZ28_RS06310	COG2095	MarC family integral membrane protein
ADZ28_RS06320	COG4166	transmembrane transport
ADZ28_RS06335	COG4166	transmembrane transport
ADZ28_RS06340	COG0601	transmembrane transport
ADZ28_RS06345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADZ28_RS06350	COG0444	Belongs to the ABC transporter superfamily
ADZ28_RS06355	COG4608	Belongs to the ABC transporter superfamily
ADZ28_RS06375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADZ28_RS06380	COG2350	Protein conserved in bacteria
ADZ28_RS06385	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ADZ28_RS06390	COG1607	acyl-coa hydrolase
ADZ28_RS06405	COG3047	cAMP biosynthetic process
ADZ28_RS06410	COG3685	Protein conserved in bacteria
ADZ28_RS06415	COG3685	Protein conserved in bacteria
ADZ28_RS06420	COG3729	General stress protein
ADZ28_RS06435	COG0135	phosphoribosylanthranilate isomerase activity
ADZ28_RS06435	COG0134	indole-3-glycerol-phosphate synthase activity
ADZ28_RS06440	COG0512	Glutamine amidotransferase of anthranilate synthase
ADZ28_RS06440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADZ28_RS06445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADZ28_RS06450	COG0613	PHP domain protein
ADZ28_RS06455	COG0009	L-threonylcarbamoyladenylate synthase
ADZ28_RS06460	COG4907	membrane protein (DUF2207)
ADZ28_RS06465	COG1187	pseudouridine synthase activity
ADZ28_RS06470	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ADZ28_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS06485	COG0616	signal peptide processing
ADZ28_RS06500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADZ28_RS06505	COG0583	DNA-binding transcription factor activity
ADZ28_RS06525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADZ28_RS06535	COG0671	phosphoesterase, PA-phosphatase related
ADZ28_RS06540	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ADZ28_RS06545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ADZ28_RS06555	COG0023	Translation Initiation Factor
ADZ28_RS06565	COG1349	DNA-binding transcription factor activity
ADZ28_RS06575	COG5001	Diguanylate cyclase
ADZ28_RS06590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADZ28_RS06590	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADZ28_RS06595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADZ28_RS06600	COG2852	Protein conserved in bacteria
ADZ28_RS06605	COG4172	Belongs to the ABC transporter superfamily
ADZ28_RS06610	COG4172	Belongs to the ABC transporter superfamily
ADZ28_RS06615	COG4171	peptide transport system, permease
ADZ28_RS06620	COG4168	peptide transport system, permease
ADZ28_RS06625	COG4166	transmembrane transport
ADZ28_RS06640	COG0531	amino acid
ADZ28_RS06645	COG0174	glutamine synthetase
ADZ28_RS06650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ADZ28_RS06655	COG1917	Cupin 2, conserved barrel domain protein
ADZ28_RS06655	COG1396	sequence-specific DNA binding
ADZ28_RS06660	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS06665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADZ28_RS06670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADZ28_RS06675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ADZ28_RS06680	COG1842	Phage shock protein A
ADZ28_RS06690	COG1983	PspC domain protein
ADZ28_RS06700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADZ28_RS06705	COG0366	Alpha amylase catalytic
ADZ28_RS06710	COG1653	transport
ADZ28_RS06715	COG1175	transmembrane transport
ADZ28_RS06720	COG0395	ABC-type sugar transport system, permease component
ADZ28_RS06725	COG1063	alcohol dehydrogenase
ADZ28_RS06730	COG1082	Xylose isomerase domain protein TIM barrel
ADZ28_RS06735	COG0673	inositol 2-dehydrogenase activity
ADZ28_RS06740	COG1554	hydrolase, family 65, central catalytic
ADZ28_RS06745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADZ28_RS06760	COG1609	Transcriptional regulator
ADZ28_RS06765	COG3106	COG3106 Predicted ATPase
ADZ28_RS06770	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ADZ28_RS06775	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ADZ28_RS06780	COG4948	Mandelate Racemase Muconate Lactonizing
ADZ28_RS06785	COG2866	Carboxypeptidase
ADZ28_RS06790	COG0702	epimerase
ADZ28_RS06795	COG1073	alpha beta
ADZ28_RS06800	COG0583	DNA-binding transcription factor activity
ADZ28_RS06810	COG4166	transmembrane transport
ADZ28_RS06815	COG0668	transmembrane transport
ADZ28_RS06825	COG3182	Iron-regulated membrane protein
ADZ28_RS06830	COG0589	response to stress
ADZ28_RS06835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADZ28_RS06845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADZ28_RS06850	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ADZ28_RS06860	COG1473	amidohydrolase
ADZ28_RS06865	COG0583	DNA-binding transcription factor activity
ADZ28_RS06875	COG2840	Smr protein MutS2
ADZ28_RS06880	COG3706	GGDEF domain
ADZ28_RS06895	COG0513	Belongs to the DEAD box helicase family
ADZ28_RS06905	COG0582	viral genome integration into host DNA
ADZ28_RS06925	COG3723	Recombinational DNA repair protein, rece pathway
ADZ28_RS06930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADZ28_RS06965	COG4197	protein conserved in bacteria, prophage-related
ADZ28_RS06975	COG3756	Protein conserved in bacteria
ADZ28_RS06980	COG1484	DNA-dependent DNA replication
ADZ28_RS06985	COG1846	Transcriptional regulator
ADZ28_RS06995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADZ28_RS07000	COG1475	DNA binding
ADZ28_RS07015	COG1196	nuclear chromosome segregation
ADZ28_RS07025	COG3039	Transposase
ADZ28_RS07045	COG5301	cellulose 1,4-beta-cellobiosidase activity
ADZ28_RS07050	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADZ28_RS07055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ADZ28_RS07065	COG0589	response to stress
ADZ28_RS07070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADZ28_RS07075	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADZ28_RS07075	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADZ28_RS07075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADZ28_RS07075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADZ28_RS07080	COG3042	response to heat
ADZ28_RS07085	COG3187	Heat shock protein
ADZ28_RS07090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADZ28_RS07095	COG2911	Protein conserved in bacteria
ADZ28_RS07105	COG3784	Protein of unknown function (DUF1318)
ADZ28_RS07110	COG2207	Transcriptional regulator
ADZ28_RS07115	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS07120	COG3733	amine oxidase
ADZ28_RS07125	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS07125	COG2030	dehydratase
ADZ28_RS07130	COG3396	Phenylacetate-CoA oxygenase
ADZ28_RS07135	COG3460	Phenylacetate-CoA oxygenase
ADZ28_RS07140	COG3396	Phenylacetate-CoA oxygenase
ADZ28_RS07145	COG2151	metal-sulfur cluster biosynthetic enzyme
ADZ28_RS07150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADZ28_RS07155	COG1024	Enoyl-CoA hydratase
ADZ28_RS07160	COG1024	Enoyl-CoA hydratase
ADZ28_RS07165	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADZ28_RS07170	COG2050	protein possibly involved in aromatic compounds catabolism
ADZ28_RS07175	COG0183	Belongs to the thiolase family
ADZ28_RS07180	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADZ28_RS07185	COG3327	negative regulation of DNA-templated transcription, initiation
ADZ28_RS07190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ADZ28_RS07210	COG2826	transposase and inactivated derivatives, IS30 family
ADZ28_RS07220	COG0667	Aldo Keto reductase
ADZ28_RS07230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADZ28_RS07235	COG4589	Belongs to the CDS family
ADZ28_RS07240	COG2267	carboxylic ester hydrolase activity
ADZ28_RS07245	COG0671	phosphoesterase, PA-phosphatase related
ADZ28_RS07245	COG2453	phosphatase
ADZ28_RS07255	COG1643	Atp-dependent helicase
ADZ28_RS07260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ADZ28_RS07265	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS07270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADZ28_RS07275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADZ28_RS07280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADZ28_RS07285	COG3038	cytochrome b561
ADZ28_RS07300	COG0840	transmembrane signaling receptor activity
ADZ28_RS07305	COG0583	DNA-binding transcription factor activity
ADZ28_RS07310	COG5383	Protein conserved in bacteria
ADZ28_RS07325	COG2841	Protein conserved in bacteria
ADZ28_RS07330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADZ28_RS07335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ADZ28_RS07340	COG1275	C4-dicarboxylate transporter malic acid transport protein
ADZ28_RS07345	COG0500	methyltransferase
ADZ28_RS07365	COG0675	Transposase, IS605 OrfB family
ADZ28_RS07370	COG3135	benzoate transporter
ADZ28_RS07375	COG1396	sequence-specific DNA binding
ADZ28_RS07380	COG0826	peptidase U32
ADZ28_RS07390	COG1724	mRNA binding
ADZ28_RS07395	COG1598	PFAM Uncharacterised protein family UPF0150
ADZ28_RS07400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADZ28_RS07405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADZ28_RS07410	COG3842	ATPase activity
ADZ28_RS07415	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADZ28_RS07420	COG1177	transmembrane transport
ADZ28_RS07445	COG3238	Protein conserved in bacteria
ADZ28_RS07450	COG1247	-acetyltransferase
ADZ28_RS07455	COG2130	NADP-dependent
ADZ28_RS07460	COG1802	Transcriptional regulator
ADZ28_RS07465	COG4772	TonB-dependent receptor
ADZ28_RS07470	COG3391	amine dehydrogenase activity
ADZ28_RS07475	COG1113	amino acid transport
ADZ28_RS07480	COG0625	glutathione transferase activity
ADZ28_RS07490	COG3209	COG3209 Rhs family protein
ADZ28_RS07500	COG5433	transposase activity
ADZ28_RS07505	COG5433	transposase activity
ADZ28_RS07515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADZ28_RS07520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ADZ28_RS07525	COG0384	phenazine biosynthesis protein PhzF
ADZ28_RS07530	COG2181	nitrate reductase activity
ADZ28_RS07535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ADZ28_RS07540	COG1140	nitrate reductase beta subunit
ADZ28_RS07545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ADZ28_RS07550	COG2223	nitrite transmembrane transporter activity
ADZ28_RS07560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADZ28_RS07565	COG0697	spore germination
ADZ28_RS07570	COG0243	molybdopterin cofactor binding
ADZ28_RS07570	COG3383	formate dehydrogenase (NAD+) activity
ADZ28_RS07575	COG0243	molybdopterin cofactor binding
ADZ28_RS07575	COG3383	formate dehydrogenase (NAD+) activity
ADZ28_RS07580	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS07585	COG2864	formate dehydrogenase
ADZ28_RS07590	COG3093	addiction module antidote protein HigA
ADZ28_RS07595	COG1064	alcohol dehydrogenase
ADZ28_RS07615	COG1764	response to oxidative stress
ADZ28_RS07620	COG4608	Belongs to the ABC transporter superfamily
ADZ28_RS07625	COG0444	Belongs to the ABC transporter superfamily
ADZ28_RS07630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADZ28_RS07635	COG0601	transmembrane transport
ADZ28_RS07640	COG0747	negative chemotaxis
ADZ28_RS07645	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ADZ28_RS07650	COG2200	EAL domain
ADZ28_RS07650	COG2202	Pas domain
ADZ28_RS07650	COG2199	diguanylate cyclase activity
ADZ28_RS07655	COG3706	GGDEF domain
ADZ28_RS07660	COG1649	PFAM Uncharacterised BCR, COG1649
ADZ28_RS07665	COG0531	amino acid
ADZ28_RS07670	COG0076	glutamate decarboxylase activity
ADZ28_RS07680	COG0612	Peptidase, M16
ADZ28_RS07685	COG4771	TonB-dependent receptor
ADZ28_RS07690	COG4178	(ABC) transporter
ADZ28_RS07695	COG0641	radical SAM
ADZ28_RS07700	COG3119	arylsulfatase activity
ADZ28_RS07705	COG2207	Transcriptional regulator
ADZ28_RS07715	COG0243	molybdopterin cofactor binding
ADZ28_RS07720	COG3539	Fimbrial protein
ADZ28_RS07725	COG3539	Fimbrial protein
ADZ28_RS07730	COG3539	Fimbrial protein
ADZ28_RS07735	COG3188	usher protein
ADZ28_RS07740	COG4977	sequence-specific DNA binding
ADZ28_RS07745	COG3550	peptidyl-serine autophosphorylation
ADZ28_RS07750	COG1396	sequence-specific DNA binding
ADZ28_RS07760	COG2911	Protein conserved in bacteria
ADZ28_RS07760	COG3210	domain, Protein
ADZ28_RS07810	COG3781	membrane
ADZ28_RS07825	COG2199	diguanylate cyclase activity
ADZ28_RS07835	COG2066	Belongs to the glutaminase family
ADZ28_RS07840	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS07845	COG0583	DNA-binding transcription factor activity
ADZ28_RS07865	COG1846	Transcriptional regulator
ADZ28_RS07870	COG4977	sequence-specific DNA binding
ADZ28_RS07880	COG0697	spore germination
ADZ28_RS07885	COG2814	Major facilitator Superfamily
ADZ28_RS07895	COG3706	GGDEF domain
ADZ28_RS07900	COG3111	PFAM Bacterial OB fold (BOF) protein
ADZ28_RS07905	COG1546	Belongs to the CinA family
ADZ28_RS07910	COG0339	signal peptide processing
ADZ28_RS07915	COG4221	oxidoreductase activity
ADZ28_RS07920	COG1802	Transcriptional regulator
ADZ28_RS07930	COG0246	Mannitol dehydrogenase
ADZ28_RS07935	COG0477	Major facilitator Superfamily
ADZ28_RS07945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ADZ28_RS07950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADZ28_RS07955	COG5301	cellulose 1,4-beta-cellobiosidase activity
ADZ28_RS07960	COG4220	transposase activity
ADZ28_RS07970	COG5562	phage envelope protein
ADZ28_RS07985	COG1278	Cold shock
ADZ28_RS07995	COG3772	lysozyme
ADZ28_RS08010	COG1278	Cold shock
ADZ28_RS08015	COG1278	Cold shock
ADZ28_RS08020	COG0484	heat shock protein binding
ADZ28_RS08025	COG1403	HNH endonuclease
ADZ28_RS08045	COG2026	Addiction module toxin, RelE StbE family
ADZ28_RS08050	COG3077	Addiction module antitoxin, RelB DinJ family
ADZ28_RS08070	COG1396	sequence-specific DNA binding
ADZ28_RS08110	COG0582	viral genome integration into host DNA
ADZ28_RS08115	COG1063	alcohol dehydrogenase
ADZ28_RS08120	COG4948	Mandelate Racemase Muconate Lactonizing
ADZ28_RS08135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADZ28_RS08150	COG0243	molybdopterin cofactor binding
ADZ28_RS08155	COG0243	molybdopterin cofactor binding
ADZ28_RS08160	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS08165	COG3302	dmso reductase anchor subunit
ADZ28_RS08170	COG3381	protein complex oligomerization
ADZ28_RS08180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADZ28_RS08185	COG1940	carbohydrate kinase activity
ADZ28_RS08190	COG0583	DNA-binding transcription factor activity
ADZ28_RS08195	COG2814	Major facilitator Superfamily
ADZ28_RS08210	COG3591	Belongs to the peptidase S1B family
ADZ28_RS08225	COG0628	permease
ADZ28_RS08230	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ADZ28_RS08235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ADZ28_RS08245	COG0531	amino acid
ADZ28_RS08255	COG3136	membrane protein required for alginate biosynthesis
ADZ28_RS08260	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS08265	COG2205	protein histidine kinase activity
ADZ28_RS08275	COG0114	fumarate hydratase activity
ADZ28_RS08280	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADZ28_RS08280	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ADZ28_RS08285	COG1482	cell wall glycoprotein biosynthetic process
ADZ28_RS08290	COG5339	Protein conserved in bacteria
ADZ28_RS08300	COG2211	Major facilitator Superfamily
ADZ28_RS08305	COG3250	beta-galactosidase activity
ADZ28_RS08310	COG1309	transcriptional regulator
ADZ28_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS08320	COG1609	Transcriptional regulator
ADZ28_RS08325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS08325	COG1263	PTS System
ADZ28_RS08330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ADZ28_RS08340	COG0673	inositol 2-dehydrogenase activity
ADZ28_RS08380	COG4659	FMN binding
ADZ28_RS08390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADZ28_RS08400	COG3104	oligopeptide transport
ADZ28_RS08405	COG0625	glutathione transferase activity
ADZ28_RS08410	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ADZ28_RS08425	COG3895	Periplasmic Protein
ADZ28_RS08435	COG3133	Outer membrane lipoprotein
ADZ28_RS08450	COG1566	PFAM secretion protein HlyD family protein
ADZ28_RS08455	COG1289	transmembrane transporter activity
ADZ28_RS08460	COG2032	superoxide dismutase activity
ADZ28_RS08465	COG4989	oxidoreductase activity
ADZ28_RS08470	COG3313	Fe-S protein
ADZ28_RS08475	COG1309	transcriptional regulator
ADZ28_RS08480	COG1902	pentaerythritol trinitrate reductase activity
ADZ28_RS08485	COG0346	lactoylglutathione lyase activity
ADZ28_RS08490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADZ28_RS08495	COG1201	RNA secondary structure unwinding
ADZ28_RS08500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ADZ28_RS08505	COG0791	NLP P60 protein
ADZ28_RS08510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADZ28_RS08515	COG2814	Major facilitator Superfamily
ADZ28_RS08530	COG0583	DNA-binding transcription factor activity
ADZ28_RS08535	COG2814	Major facilitator Superfamily
ADZ28_RS08540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ADZ28_RS08545	COG0307	riboflavin synthase, alpha
ADZ28_RS08560	COG3468	outer membrane autotransporter barrel domain protein
ADZ28_RS08580	COG4529	Protein conserved in bacteria
ADZ28_RS08590	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ADZ28_RS08595	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS08605	COG2414	aldehyde ferredoxin oxidoreductase
ADZ28_RS08610	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS08620	COG0469	pyruvate kinase activity
ADZ28_RS08625	COG4238	major outer membrane lipoprotein
ADZ28_RS08630	COG1376	ErfK ybiS ycfS ynhG family protein
ADZ28_RS08645	COG0719	Fe-S assembly protein
ADZ28_RS08650	COG0396	ATPase activity
ADZ28_RS08655	COG0719	Fe-S assembly protein
ADZ28_RS08660	COG0316	Belongs to the HesB IscA family
ADZ28_RS08670	COG2050	protein possibly involved in aromatic compounds catabolism
ADZ28_RS08675	COG0277	FAD linked oxidase domain protein
ADZ28_RS08675	COG0247	lactate metabolic process
ADZ28_RS08680	COG0628	permease
ADZ28_RS08690	COG0738	Major facilitator superfamily
ADZ28_RS08695	COG2271	Major facilitator Superfamily
ADZ28_RS08710	COG4670	ketone body catabolic process
ADZ28_RS08715	COG1960	acyl-CoA dehydrogenase activity
ADZ28_RS08720	COG2207	Transcriptional regulator
ADZ28_RS08720	COG1917	Cupin 2, conserved barrel domain protein
ADZ28_RS08730	COG2086	electron transfer activity
ADZ28_RS08735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADZ28_RS08740	COG0644	oxidoreductase
ADZ28_RS08745	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ADZ28_RS08750	COG0318	PFAM AMP-dependent synthetase and ligase
ADZ28_RS08755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADZ28_RS08755	COG0574	Belongs to the PEP-utilizing enzyme family
ADZ28_RS08770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ADZ28_RS08775	COG4256	Hemin uptake protein
ADZ28_RS08785	COG2200	EAL domain
ADZ28_RS08790	COG0791	NLP P60 protein
ADZ28_RS08800	COG0386	Belongs to the glutathione peroxidase family
ADZ28_RS08815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADZ28_RS08815	COG0072	phenylalanine-tRNA ligase activity
ADZ28_RS08860	COG3137	Salt-induced outer membrane protein
ADZ28_RS08865	COG1105	Belongs to the carbohydrate kinase PfkB family
ADZ28_RS08875	COG3001	Fructosamine kinase
ADZ28_RS08885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADZ28_RS08890	COG1988	membrane-bound metal-dependent
ADZ28_RS08895	COG1823	symporter activity
ADZ28_RS08910	COG0753	catalase activity
ADZ28_RS08920	COG1486	melibiose metabolic process
ADZ28_RS08925	COG2169	Transcriptional regulator
ADZ28_RS08925	COG1917	Cupin 2, conserved barrel domain protein
ADZ28_RS08930	COG1447	Phosphotransferase system cellobiose-specific component IIA
ADZ28_RS08935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ADZ28_RS08940	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ADZ28_RS08945	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADZ28_RS08960	COG0322	excinuclease ABC activity
ADZ28_RS08970	COG3678	ATP-independent chaperone mediated protein folding
ADZ28_RS09000	COG0708	Exodeoxyribonuclease III
ADZ28_RS09005	COG0398	Pfam SNARE associated Golgi protein
ADZ28_RS09015	COG0398	Pfam SNARE associated Golgi protein
ADZ28_RS09020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADZ28_RS09025	COG4134	Bacterial extracellular solute-binding protein
ADZ28_RS09030	COG4135	transport system, permease component
ADZ28_RS09035	COG4136	ATPase activity
ADZ28_RS09040	COG2897	thiosulfate sulfurtransferase activity
ADZ28_RS09045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADZ28_RS09050	COG0494	nUDIX hydrolase
ADZ28_RS09060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADZ28_RS09070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADZ28_RS09085	COG0778	Nitroreductase
ADZ28_RS09095	COG0616	signal peptide processing
ADZ28_RS09100	COG0252	asparaginase activity
ADZ28_RS09105	COG1335	isochorismatase
ADZ28_RS09110	COG2814	Major facilitator Superfamily
ADZ28_RS09115	COG1349	DNA-binding transcription factor activity
ADZ28_RS09120	COG0667	Aldo Keto reductase
ADZ28_RS09125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS09130	COG0191	fructose-bisphosphate aldolase activity
ADZ28_RS09135	COG1063	alcohol dehydrogenase
ADZ28_RS09140	COG2271	Major facilitator Superfamily
ADZ28_RS09145	COG1063	alcohol dehydrogenase
ADZ28_RS09150	COG3139	Protein of unknown function (DUF1315)
ADZ28_RS09160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADZ28_RS09165	COG0676	glucose-6-phosphate 1-epimerase activity
ADZ28_RS09170	COG0656	L-ascorbic acid biosynthetic process
ADZ28_RS09175	COG3713	MltA-interacting MipA family protein
ADZ28_RS09180	COG2766	serine protein kinase
ADZ28_RS09190	COG2199	diguanylate cyclase activity
ADZ28_RS09195	COG2199	diguanylate cyclase activity
ADZ28_RS09200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADZ28_RS09215	COG2207	Transcriptional regulator
ADZ28_RS09220	COG2807	transmembrane transport
ADZ28_RS09225	COG3189	MarR family transcriptional regulator
ADZ28_RS09230	COG3042	response to heat
ADZ28_RS09235	COG2199	diguanylate cyclase activity
ADZ28_RS09235	COG2203	Gaf domain
ADZ28_RS09245	COG2261	transglycosylase associated protein
ADZ28_RS09255	COG3615	Tellurite resistance protein tehB
ADZ28_RS09265	COG0583	DNA-binding transcription factor activity
ADZ28_RS09270	COG0473	3-isopropylmalate dehydrogenase activity
ADZ28_RS09275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADZ28_RS09280	COG4638	Rieske (2fe-2S)
ADZ28_RS09285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADZ28_RS09290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ADZ28_RS09295	COG0318	PFAM AMP-dependent synthetase and ligase
ADZ28_RS09300	COG3065	identical protein binding
ADZ28_RS09305	COG1214	PFAM Peptidase M22, glycoprotease
ADZ28_RS09310	COG1199	ATP-dependent helicase activity
ADZ28_RS09315	COG0251	oxidation-reduction process
ADZ28_RS09330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADZ28_RS09340	COG1760	l-serine dehydratase
ADZ28_RS09345	COG2200	EAL domain
ADZ28_RS09350	COG1253	flavin adenine dinucleotide binding
ADZ28_RS09360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS09360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS09365	COG3715	PTS system
ADZ28_RS09370	COG3716	PTS system mannose fructose sorbose family IID component
ADZ28_RS09390	COG2226	methyltransferase
ADZ28_RS09425	COG1414	Transcriptional regulator
ADZ28_RS09435	COG1414	Transcriptional regulator
ADZ28_RS09440	COG2814	Major facilitator Superfamily
ADZ28_RS09450	COG0793	Belongs to the peptidase S41A family
ADZ28_RS09460	COG1956	GAF domain-containing protein
ADZ28_RS09465	COG2995	paraquat-inducible protein a
ADZ28_RS09470	COG3008	intermembrane lipid transfer
ADZ28_RS09490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADZ28_RS09505	COG1276	copper resistance
ADZ28_RS09510	COG2372	response to copper ion
ADZ28_RS09520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADZ28_RS09525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADZ28_RS09530	COG1770	oligopeptidase
ADZ28_RS09535	COG2979	Protein of unknown function (DUF533)
ADZ28_RS09550	COG3141	response to X-ray
ADZ28_RS09560	COG0800	Aldolase
ADZ28_RS09565	COG0129	dihydroxy-acid dehydratase activity
ADZ28_RS09570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ADZ28_RS09580	COG1737	Transcriptional regulator
ADZ28_RS09585	COG0469	pyruvate kinase activity
ADZ28_RS09590	COG1560	Kdo2-lipid A biosynthetic process
ADZ28_RS09595	COG0739	heme binding
ADZ28_RS09600	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ADZ28_RS09610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADZ28_RS09635	COG0217	transcriptional regulatory protein
ADZ28_RS09640	COG0494	nUDIX hydrolase
ADZ28_RS09650	COG1335	isochorismatase
ADZ28_RS09655	COG1801	Protein of unknown function DUF72
ADZ28_RS09660	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ADZ28_RS09675	COG0243	molybdopterin cofactor binding
ADZ28_RS09680	COG3005	denitrification pathway
ADZ28_RS09690	COG3102	Protein conserved in bacteria
ADZ28_RS09700	COG3755	Protein conserved in bacteria
ADZ28_RS09710	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADZ28_RS09715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADZ28_RS09720	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ADZ28_RS09725	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS09730	COG2201	protein-glutamate methylesterase activity
ADZ28_RS09735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ADZ28_RS09740	COG0840	transmembrane signaling receptor activity
ADZ28_RS09745	COG0840	transmembrane signaling receptor activity
ADZ28_RS09750	COG0835	chemotaxis
ADZ28_RS09755	COG2198	Histidine kinase
ADZ28_RS09755	COG0643	Histidine kinase
ADZ28_RS09760	COG1360	Flagellar Motor Protein
ADZ28_RS09765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ADZ28_RS09780	COG0589	response to stress
ADZ28_RS09790	COG1877	trehalose-phosphatase activity
ADZ28_RS09795	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS09800	COG1129	ABC transporter
ADZ28_RS09805	COG1879	ABC-type sugar transport system periplasmic component
ADZ28_RS09810	COG1528	Iron-storage protein
ADZ28_RS09830	COG1528	Iron-storage protein
ADZ28_RS09840	COG0814	amino acid
ADZ28_RS09845	COG3318	Belongs to the UPF0149 family
ADZ28_RS09845	COG3012	SEC-C Motif Domain Protein
ADZ28_RS09875	COG2197	response regulator
ADZ28_RS09890	COG2197	response regulator
ADZ28_RS09895	COG1126	abc transporter atp-binding protein
ADZ28_RS09900	COG0765	amino acid transport
ADZ28_RS09910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS09920	COG1191	sigma factor activity
ADZ28_RS09925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADZ28_RS09930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ADZ28_RS09935	COG1516	flagellar protein fliS
ADZ28_RS09945	COG0366	Alpha amylase catalytic
ADZ28_RS09955	COG2391	methyltransferase activity
ADZ28_RS09960	COG0425	Belongs to the sulfur carrier protein TusA family
ADZ28_RS09965	COG2135	peptidase activity
ADZ28_RS09970	COG0454	-acetyltransferase
ADZ28_RS09995	COG1766	The M ring may be actively involved in energy transduction
ADZ28_RS10000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADZ28_RS10005	COG1317	bacterial-type flagellum organization
ADZ28_RS10010	COG1157	protein secretion by the type III secretion system
ADZ28_RS10015	COG2882	bacterial-type flagellum organization
ADZ28_RS10020	COG3144	bacterial-type flagellum assembly
ADZ28_RS10025	COG1580	Controls the rotational direction of flagella during chemotaxis
ADZ28_RS10030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADZ28_RS10035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADZ28_RS10040	COG3190	flagellar
ADZ28_RS10045	COG1338	Plays a role in the flagellum-specific transport system
ADZ28_RS10050	COG1987	bacterial-type flagellum assembly
ADZ28_RS10055	COG1684	flagellar biosynthetic protein fliR
ADZ28_RS10060	COG2197	response regulator
ADZ28_RS10080	COG3706	GGDEF domain
ADZ28_RS10085	COG5475	Uncharacterized small protein (DUF2158)
ADZ28_RS10090	COG2354	Protein conserved in bacteria
ADZ28_RS10095	COG0697	spore germination
ADZ28_RS10100	COG3727	T/G mismatch-specific endonuclease activity
ADZ28_RS10105	COG0270	DNA (cytosine-5-)-methyltransferase activity
ADZ28_RS10110	COG1418	mRNA catabolic process
ADZ28_RS10135	COG2205	protein histidine kinase activity
ADZ28_RS10140	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS10145	COG2351	hydroxyisourate hydrolase activity
ADZ28_RS10160	COG3443	Belongs to the bacterial solute-binding protein 9 family
ADZ28_RS10165	COG3038	cytochrome b561
ADZ28_RS10190	COG1388	LysM domain
ADZ28_RS10190	COG1470	cell adhesion involved in biofilm formation
ADZ28_RS10200	COG0477	Major facilitator Superfamily
ADZ28_RS10205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADZ28_RS10210	COG0217	transcriptional regulatory protein
ADZ28_RS10220	COG0534	Mate efflux family protein
ADZ28_RS10230	COG0583	DNA-binding transcription factor activity
ADZ28_RS10235	COG0583	DNA-binding transcription factor activity
ADZ28_RS10245	COG1376	ErfK ybiS ycfS ynhG family protein
ADZ28_RS10260	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ADZ28_RS10265	COG3039	Transposase
ADZ28_RS10285	COG4771	TonB-dependent receptor
ADZ28_RS10295	COG3468	outer membrane autotransporter barrel domain protein
ADZ28_RS10305	COG2003	Belongs to the UPF0758 family
ADZ28_RS10345	COG1289	transmembrane transporter activity
ADZ28_RS10355	COG1686	Belongs to the peptidase S11 family
ADZ28_RS10360	COG2925	Exonuclease
ADZ28_RS10365	COG0425	Belongs to the sulfur carrier protein TusA family
ADZ28_RS10370	COG2391	methyltransferase activity
ADZ28_RS10375	COG0531	amino acid
ADZ28_RS10380	COG0583	DNA-binding transcription factor activity
ADZ28_RS10385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADZ28_RS10390	COG4115	mRNA cleavage
ADZ28_RS10395	COG2161	toxin-antitoxin pair type II binding
ADZ28_RS10405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADZ28_RS10415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADZ28_RS10415	COG0131	Imidazoleglycerol-phosphate dehydratase
ADZ28_RS10420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADZ28_RS10435	COG0140	phosphoribosyl-ATP diphosphatase activity
ADZ28_RS10435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADZ28_RS10440	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ADZ28_RS10445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ADZ28_RS10450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ADZ28_RS10465	COG0438	transferase activity, transferring glycosyl groups
ADZ28_RS10470	COG0110	maltose O-acetyltransferase activity
ADZ28_RS10475	COG0438	transferase activity, transferring glycosyl groups
ADZ28_RS10485	COG0562	UDP-galactopyranose mutase
ADZ28_RS10490	COG2244	polysaccharide biosynthetic process
ADZ28_RS10495	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ADZ28_RS10500	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ADZ28_RS10510	COG1088	dTDP-glucose 4,6-dehydratase activity
ADZ28_RS10515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADZ28_RS10525	COG0438	transferase activity, transferring glycosyl groups
ADZ28_RS10530	COG2327	Polysaccharide pyruvyl transferase
ADZ28_RS10535	COG2244	polysaccharide biosynthetic process
ADZ28_RS10540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADZ28_RS10545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADZ28_RS10550	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ADZ28_RS10550	COG0662	Cupin 2, conserved barrel domain protein
ADZ28_RS10555	COG0297	glycogen (starch) synthase activity
ADZ28_RS10560	COG1051	belongs to the nudix hydrolase family
ADZ28_RS10565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADZ28_RS10570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ADZ28_RS10575	COG0110	maltose O-acetyltransferase activity
ADZ28_RS10580	COG1216	Glycosyl transferase, family 2
ADZ28_RS10590	COG0438	transferase activity, transferring glycosyl groups
ADZ28_RS10595	COG1045	serine acetyltransferase
ADZ28_RS10600	COG0463	Glycosyl transferase, family 2
ADZ28_RS10605	COG3206	protein involved in exopolysaccharide biosynthesis
ADZ28_RS10605	COG0489	protein tyrosine kinase activity
ADZ28_RS10610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADZ28_RS10615	COG1596	polysaccharide export
ADZ28_RS10620	COG1253	flavin adenine dinucleotide binding
ADZ28_RS10625	COG2982	Protein involved in outer membrane biogenesis
ADZ28_RS10635	COG0572	uridine kinase
ADZ28_RS10640	COG5001	Diguanylate cyclase
ADZ28_RS10640	COG5002	protein histidine kinase activity
ADZ28_RS10640	COG3447	MASE1 domain protein
ADZ28_RS10645	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ADZ28_RS10655	COG0443	Heat shock 70 kDa protein
ADZ28_RS10660	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ADZ28_RS10665	COG3779	Protein conserved in bacteria
ADZ28_RS10670	COG0631	protein serine/threonine phosphatase activity
ADZ28_RS10675	COG4245	von Willebrand factor, type A
ADZ28_RS10700	COG2205	protein histidine kinase activity
ADZ28_RS10705	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS10710	COG3422	double-strand break repair
ADZ28_RS10715	COG0826	peptidase U32
ADZ28_RS10745	COG2801	Transposase and inactivated derivatives
ADZ28_RS10755	COG1063	alcohol dehydrogenase
ADZ28_RS10760	COG3775	system Galactitol-specific IIC component
ADZ28_RS10770	COG3414	Phosphotransferase system galactitol-specific IIB component
ADZ28_RS10775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS10790	COG1830	Aldolase
ADZ28_RS10795	COG2211	Major facilitator Superfamily
ADZ28_RS10800	COG1397	ADP-ribosylglycohydrolase
ADZ28_RS10805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS10810	COG2188	Transcriptional regulator
ADZ28_RS10815	COG3757	hydrolase, family 25
ADZ28_RS10820	COG0351	phosphomethylpyrimidine kinase
ADZ28_RS10835	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADZ28_RS10840	COG5455	response to cobalt ion
ADZ28_RS10845	COG3539	Fimbrial protein
ADZ28_RS10850	COG3188	usher protein
ADZ28_RS10855	COG3121	Chaperone
ADZ28_RS10860	COG3539	Fimbrial protein
ADZ28_RS10875	COG0489	protein tyrosine kinase activity
ADZ28_RS10895	COG3831	ATPase activity
ADZ28_RS10905	COG0714	Associated with various cellular activities
ADZ28_RS10910	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ADZ28_RS10915	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ADZ28_RS10920	COG4715	Zinc finger, swim domain protein
ADZ28_RS10925	COG4808	Protein conserved in bacteria
ADZ28_RS10930	COG4807	Protein conserved in bacteria
ADZ28_RS10935	COG3279	Response regulator of the LytR AlgR family
ADZ28_RS10940	COG3275	phosphorelay sensor kinase activity
ADZ28_RS10945	COG0789	Transcriptional regulator
ADZ28_RS10955	COG1174	glycine betaine transport
ADZ28_RS10960	COG1125	glycine betaine transport
ADZ28_RS10965	COG1174	glycine betaine transport
ADZ28_RS10970	COG1732	Glycine betaine
ADZ28_RS10975	COG1472	Belongs to the glycosyl hydrolase 3 family
ADZ28_RS10980	COG0277	FAD linked oxidase domain protein
ADZ28_RS10985	COG1686	Belongs to the peptidase S11 family
ADZ28_RS10995	COG0586	Pfam SNARE associated Golgi protein
ADZ28_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS11015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADZ28_RS11025	COG1346	cytolysis
ADZ28_RS11035	COG2949	membrane
ADZ28_RS11045	COG0493	'glutamate synthase
ADZ28_RS11050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ADZ28_RS11050	COG0167	dihydroorotate dehydrogenase activity
ADZ28_RS11055	COG4211	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS11060	COG1129	ABC transporter
ADZ28_RS11065	COG1879	ABC-type sugar transport system periplasmic component
ADZ28_RS11070	COG1609	Transcriptional regulator
ADZ28_RS11080	COG2311	Membrane
ADZ28_RS11100	COG4771	TonB-dependent receptor
ADZ28_RS11105	COG0833	amino acid
ADZ28_RS11110	COG0583	DNA-binding transcription factor activity
ADZ28_RS11115	COG2855	membrane
ADZ28_RS11125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS11125	COG1522	sequence-specific DNA binding
ADZ28_RS11130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADZ28_RS11140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADZ28_RS11145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADZ28_RS11150	COG2313	pseudouridylate synthase activity
ADZ28_RS11155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS11160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS11160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS11160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ADZ28_RS11165	COG1105	Belongs to the carbohydrate kinase PfkB family
ADZ28_RS11170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS11170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS11175	COG2814	Major facilitator Superfamily
ADZ28_RS11190	COG0246	Mannitol dehydrogenase
ADZ28_RS11195	COG0523	cobalamin synthesis protein
ADZ28_RS11200	COG0671	phosphoesterase, PA-phosphatase related
ADZ28_RS11205	COG0791	NLP P60 protein
ADZ28_RS11210	COG2200	EAL domain
ADZ28_RS11215	COG4166	transmembrane transport
ADZ28_RS11220	COG4174	ABC transporter (Permease)
ADZ28_RS11225	COG4239	(ABC) transporter, permease
ADZ28_RS11230	COG4172	Belongs to the ABC transporter superfamily
ADZ28_RS11240	COG2814	Major facilitator Superfamily
ADZ28_RS11245	COG1187	pseudouridine synthase activity
ADZ28_RS11250	COG1061	Type III restriction enzyme res subunit
ADZ28_RS11270	COG3083	sulfuric ester hydrolase activity
ADZ28_RS11280	COG3468	outer membrane autotransporter barrel domain protein
ADZ28_RS11295	COG2197	response regulator
ADZ28_RS11300	COG3088	subunit of a heme lyase
ADZ28_RS11300	COG4235	cytochrome complex assembly
ADZ28_RS11305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADZ28_RS11310	COG1138	Cytochrome C-type biogenesis protein
ADZ28_RS11320	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADZ28_RS11325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADZ28_RS11330	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADZ28_RS11335	COG4133	protoheme IX ABC transporter activity
ADZ28_RS11340	COG3005	denitrification pathway
ADZ28_RS11345	COG3043	anaerobic respiration
ADZ28_RS11350	COG0348	domain, Protein
ADZ28_RS11355	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS11365	COG3062	negative regulation of establishment of protein localization
ADZ28_RS11370	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS11370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS11390	COG4615	Cyclic peptide transporter
ADZ28_RS11395	COG3145	DNA-N1-methyladenine dioxygenase activity
ADZ28_RS11400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADZ28_RS11400	COG2169	Transcriptional regulator
ADZ28_RS11405	COG1477	protein flavinylation
ADZ28_RS11410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ADZ28_RS11425	COG2198	Histidine kinase
ADZ28_RS11425	COG0642	Histidine kinase
ADZ28_RS11430	COG2197	response regulator
ADZ28_RS11435	COG0784	Response regulator, receiver
ADZ28_RS11435	COG2205	protein histidine kinase activity
ADZ28_RS11440	COG3852	Histidine kinase
ADZ28_RS11445	COG2204	response regulator
ADZ28_RS11450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ADZ28_RS11455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADZ28_RS11460	COG2031	fatty acid transporter
ADZ28_RS11465	COG0183	Belongs to the thiolase family
ADZ28_RS11470	COG4676	Protein conserved in bacteria
ADZ28_RS11475	COG5445	Predicted secreted protein (DUF2300)
ADZ28_RS11480	COG2373	Large extracellular alpha-helical protein
ADZ28_RS11490	COG3234	Protein of unknown function (DUF1175)
ADZ28_RS11495	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ADZ28_RS11500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADZ28_RS11510	COG3468	outer membrane autotransporter barrel domain protein
ADZ28_RS11520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADZ28_RS11525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADZ28_RS11530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADZ28_RS11535	COG3642	lipopolysaccharide core region biosynthetic process
ADZ28_RS11540	COG0583	DNA-binding transcription factor activity
ADZ28_RS11545	COG0584	glycerophosphoryl diester phosphodiesterase
ADZ28_RS11550	COG2271	Major facilitator Superfamily
ADZ28_RS11555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADZ28_RS11565	COG0247	lactate metabolic process
ADZ28_RS11570	COG5464	transposase or invertase
ADZ28_RS11585	COG2271	Major facilitator Superfamily
ADZ28_RS11595	COG1414	Transcriptional regulator
ADZ28_RS11660	COG0318	PFAM AMP-dependent synthetase and ligase
ADZ28_RS11670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADZ28_RS11685	COG1169	isochorismate synthase
ADZ28_RS11690	COG4575	ribosome binding
ADZ28_RS11695	COG2153	protein acetylation
ADZ28_RS11705	COG5160	protein modification by small protein removal
ADZ28_RS11710	COG2304	oxidoreductase activity
ADZ28_RS11715	COG2234	aminopeptidase activity
ADZ28_RS11735	COG0457	Tetratricopeptide repeat
ADZ28_RS11745	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADZ28_RS11750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADZ28_RS11760	COG0839	Belongs to the complex I subunit 6 family
ADZ28_RS11775	COG1034	ATP synthesis coupled electron transport
ADZ28_RS11780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ADZ28_RS11785	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ADZ28_RS11805	COG0583	DNA-binding transcription factor activity
ADZ28_RS11810	COG0436	Aminotransferase
ADZ28_RS11820	COG0471	metal ion transport
ADZ28_RS11820	COG0490	domain, Protein
ADZ28_RS11825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADZ28_RS11845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADZ28_RS11850	COG0280	phosphate acetyltransferase
ADZ28_RS11850	COG0857	belongs to the CobB CobQ family
ADZ28_RS11855	COG1288	antiporter activity
ADZ28_RS11860	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ADZ28_RS11865	COG0622	Phosphoesterase
ADZ28_RS11870	COG0625	glutathione transferase activity
ADZ28_RS11875	COG0625	glutathione transferase activity
ADZ28_RS11880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ADZ28_RS11885	COG1090	epimerase
ADZ28_RS11890	COG5464	transposase or invertase
ADZ28_RS11895	COG4598	ABC transporter
ADZ28_RS11900	COG4160	amino acid transport
ADZ28_RS11905	COG4215	(ABC) transporter
ADZ28_RS11910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS11915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS11920	COG0163	prenyltransferase activity
ADZ28_RS11925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADZ28_RS11930	COG1286	toxin biosynthetic process
ADZ28_RS11935	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ADZ28_RS11940	COG0285	dihydrofolate synthase activity
ADZ28_RS11950	COG0586	Pfam SNARE associated Golgi protein
ADZ28_RS11960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADZ28_RS11975	COG2814	Major facilitator Superfamily
ADZ28_RS11980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADZ28_RS11995	COG3101	peptidyl-lysine hydroxylation
ADZ28_RS12000	COG0730	response to heat
ADZ28_RS12015	COG2890	protein-(glutamine-N5) methyltransferase activity
ADZ28_RS12030	COG3539	Fimbrial protein
ADZ28_RS12035	COG3539	Fimbrial protein
ADZ28_RS12040	COG3539	Fimbrial protein
ADZ28_RS12045	COG3121	Chaperone
ADZ28_RS12055	COG3539	Fimbrial protein
ADZ28_RS12060	COG2062	phosphohistidine phosphatase, SixA
ADZ28_RS12075	COG3691	Protein conserved in bacteria
ADZ28_RS12080	COG2067	long-chain fatty acid transport protein
ADZ28_RS12090	COG2853	Lipoprotein
ADZ28_RS12095	COG2116	formate transmembrane transporter activity
ADZ28_RS12105	COG0582	viral genome integration into host DNA
ADZ28_RS12110	COG2246	polysaccharide biosynthetic process
ADZ28_RS12115	COG0463	Glycosyl transferase, family 2
ADZ28_RS12140	COG4725	Belongs to the MT-A70-like family
ADZ28_RS12150	COG1846	Transcriptional regulator
ADZ28_RS12160	COG5532	Uncharacterized conserved protein (DUF2303)
ADZ28_RS12165	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ADZ28_RS12185	COG0583	DNA-binding transcription factor activity
ADZ28_RS12190	COG2610	gluconate transmembrane transporter activity
ADZ28_RS12200	COG0477	Major facilitator Superfamily
ADZ28_RS12205	COG1566	PFAM secretion protein HlyD family protein
ADZ28_RS12210	COG2197	response regulator
ADZ28_RS12215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS12215	COG2205	protein histidine kinase activity
ADZ28_RS12215	COG2198	Histidine kinase
ADZ28_RS12215	COG0784	Response regulator, receiver
ADZ28_RS12220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ADZ28_RS12225	COG0679	Auxin Efflux Carrier
ADZ28_RS12230	COG0028	Belongs to the TPP enzyme family
ADZ28_RS12260	COG1560	Kdo2-lipid A biosynthetic process
ADZ28_RS12265	COG0436	Aminotransferase
ADZ28_RS12270	COG3275	phosphorelay sensor kinase activity
ADZ28_RS12275	COG3279	Response regulator of the LytR AlgR family
ADZ28_RS12280	COG2207	Transcriptional regulator
ADZ28_RS12285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS12285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS12285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADZ28_RS12290	COG1363	Peptidase, m42
ADZ28_RS12295	COG0006	proline dipeptidase activity
ADZ28_RS12300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS12305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS12335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ADZ28_RS12340	COG3385	transposase activity
ADZ28_RS12345	COG2199	diguanylate cyclase activity
ADZ28_RS12345	COG2200	EAL domain
ADZ28_RS12360	COG3415	Transposase
ADZ28_RS12365	COG3415	Transposase
ADZ28_RS12395	COG0583	DNA-binding transcription factor activity
ADZ28_RS12405	COG2211	Major facilitator Superfamily
ADZ28_RS12410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ADZ28_RS12420	COG0583	DNA-binding transcription factor activity
ADZ28_RS12425	COG0385	Bile acid
ADZ28_RS12430	COG3530	Putative quorum-sensing-regulated virulence factor
ADZ28_RS12450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADZ28_RS12455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS12460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADZ28_RS12465	COG2190	(PTS) system
ADZ28_RS12480	COG4884	unkown
ADZ28_RS12480	COG3831	ATPase activity
ADZ28_RS12485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADZ28_RS12490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADZ28_RS12495	COG4208	sulfate ABC transporter
ADZ28_RS12500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ADZ28_RS12505	COG4150	thiosulfate binding
ADZ28_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS12525	COG1263	PTS System
ADZ28_RS12525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS12530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ADZ28_RS12535	COG2837	iron assimilation
ADZ28_RS12550	COG0456	acetyltransferase
ADZ28_RS12555	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADZ28_RS12565	COG2207	Transcriptional regulator
ADZ28_RS12570	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ADZ28_RS12575	COG4816	utilization protein
ADZ28_RS12585	COG4303	Ethanolamine ammonia lyase large subunit
ADZ28_RS12590	COG4819	ethanolamine utilization protein
ADZ28_RS12595	COG3192	ethanolamine utilization protein
ADZ28_RS12600	COG1454	alcohol dehydrogenase
ADZ28_RS12605	COG4820	ethanolamine utilization protein (EutJ)
ADZ28_RS12610	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS12615	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ADZ28_RS12620	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ADZ28_RS12625	COG0280	phosphate acetyltransferase
ADZ28_RS12630	COG4812	Cobalamin adenosyltransferase
ADZ28_RS12635	COG4766	ethanolamine catabolic process
ADZ28_RS12640	COG4917	ethanolamine utilization protein
ADZ28_RS12645	COG4810	utilization protein
ADZ28_RS12650	COG0280	phosphate acetyltransferase
ADZ28_RS12650	COG0281	malic enzyme
ADZ28_RS12655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADZ28_RS12660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADZ28_RS12665	COG5342	invasion associated locus B
ADZ28_RS12675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS12675	COG0493	'glutamate synthase
ADZ28_RS12680	COG3850	Histidine kinase
ADZ28_RS12685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADZ28_RS12695	COG1393	Belongs to the ArsC family
ADZ28_RS12710	COG0400	carboxylic ester hydrolase activity
ADZ28_RS12715	COG1444	tRNA N-acetyltransferase activity
ADZ28_RS12720	COG2321	neutral zinc metallopeptidase
ADZ28_RS12735	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ADZ28_RS12745	COG2716	regulation of RNA biosynthetic process
ADZ28_RS12750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADZ28_RS12755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS12760	COG0651	ATP synthesis coupled electron transport
ADZ28_RS12765	COG0650	Formate hydrogenlyase subunit 4
ADZ28_RS12770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADZ28_RS12775	COG4237	Hydrogenase 4 membrane
ADZ28_RS12780	COG0651	ATP synthesis coupled electron transport
ADZ28_RS12785	COG3261	NADH dehydrogenase
ADZ28_RS12785	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ADZ28_RS12790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADZ28_RS12795	COG3260	NADH ubiquinone oxidoreductase 20
ADZ28_RS12805	COG3604	Transcriptional regulator
ADZ28_RS12810	COG2116	formate transmembrane transporter activity
ADZ28_RS12815	COG0628	permease
ADZ28_RS12820	COG4783	chaperone-mediated protein folding
ADZ28_RS12825	COG1393	Belongs to the ArsC family
ADZ28_RS12835	COG2233	PERMEase
ADZ28_RS12850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADZ28_RS12855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ADZ28_RS12860	COG0248	Ppx GppA phosphatase
ADZ28_RS12865	COG2200	EAL domain
ADZ28_RS12880	COG3133	Outer membrane lipoprotein
ADZ28_RS12895	COG0517	IMP dehydrogenase activity
ADZ28_RS12895	COG0516	GMP reductase activity
ADZ28_RS12905	COG1645	bacterial-type flagellum-dependent swarming motility
ADZ28_RS12915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADZ28_RS12920	COG2976	Protein conserved in bacteria
ADZ28_RS12950	COG4953	penicillin-binding protein 1C
ADZ28_RS12955	COG2373	Large extracellular alpha-helical protein
ADZ28_RS12960	COG2897	thiosulfate sulfurtransferase activity
ADZ28_RS12975	COG2975	iron-sulfur cluster assembly
ADZ28_RS12980	COG0633	Ferredoxin
ADZ28_RS13000	COG0822	iron-sulfur transferase activity
ADZ28_RS13020	COG0483	inositol monophosphate 1-phosphatase activity
ADZ28_RS13025	COG1073	alpha beta
ADZ28_RS13030	COG3711	transcriptional antiterminator
ADZ28_RS13035	COG2814	Major facilitator Superfamily
ADZ28_RS13040	COG0583	DNA-binding transcription factor activity
ADZ28_RS13045	COG4638	Rieske (2fe-2S)
ADZ28_RS13070	COG2259	Doxx family
ADZ28_RS13075	COG2017	converts alpha-aldose to the beta-anomer
ADZ28_RS13080	COG1063	alcohol dehydrogenase
ADZ28_RS13085	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS13090	COG1129	ABC transporter
ADZ28_RS13095	COG1879	ABC-type sugar transport system periplasmic component
ADZ28_RS13100	COG0457	Tetratricopeptide repeat
ADZ28_RS13105	COG1940	carbohydrate kinase activity
ADZ28_RS13115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADZ28_RS13115	COG1017	nitric oxide dioxygenase activity
ADZ28_RS13120	COG0347	Belongs to the P(II) protein family
ADZ28_RS13125	COG2204	response regulator
ADZ28_RS13130	COG3170	Tfp pilus assembly protein FimV
ADZ28_RS13135	COG2205	protein histidine kinase activity
ADZ28_RS13140	COG0047	phosphoribosylformylglycinamidine synthase activity
ADZ28_RS13140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADZ28_RS13155	COG0560	Phosphoserine phosphatase
ADZ28_RS13160	COG1737	Transcriptional regulator
ADZ28_RS13165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS13190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ADZ28_RS13210	COG0681	Belongs to the peptidase S26 family
ADZ28_RS13220	COG3086	response to oxidative stress
ADZ28_RS13225	COG3026	antisigma factor binding
ADZ28_RS13230	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ADZ28_RS13235	COG1595	DNA-templated transcription, initiation
ADZ28_RS13245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ADZ28_RS13255	COG0513	Belongs to the DEAD box helicase family
ADZ28_RS13265	COG0583	DNA-binding transcription factor activity
ADZ28_RS13285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADZ28_RS13295	COG3118	belongs to the thioredoxin family
ADZ28_RS13300	COG3148	PFAM DTW domain containing protein
ADZ28_RS13305	COG0045	succinate-CoA ligase (ADP-forming) activity
ADZ28_RS13305	COG1042	CoA-binding domain protein
ADZ28_RS13305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADZ28_RS13310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADZ28_RS13315	COG5544	Lipoprotein
ADZ28_RS13320	COG0477	Major facilitator Superfamily
ADZ28_RS13350	COG0542	response to heat
ADZ28_RS13355	COG1496	oxidoreductase activity
ADZ28_RS13360	COG0564	pseudouridine synthase activity
ADZ28_RS13365	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADZ28_RS13375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADZ28_RS13380	COG0077	Prephenate dehydratase
ADZ28_RS13380	COG1605	Chorismate mutase
ADZ28_RS13385	COG0287	Prephenate dehydrogenase
ADZ28_RS13385	COG1605	Chorismate mutase
ADZ28_RS13390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ADZ28_RS13405	COG2199	diguanylate cyclase activity
ADZ28_RS13410	COG2885	chlorophyll binding
ADZ28_RS13435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADZ28_RS13440	COG4137	Cytochrome C assembly protein
ADZ28_RS13445	COG4536	flavin adenine dinucleotide binding
ADZ28_RS13465	COG0497	DNA recombination
ADZ28_RS13470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADZ28_RS13480	COG2867	negative regulation of translational initiation
ADZ28_RS13490	COG0582	viral genome integration into host DNA
ADZ28_RS13500	COG3311	Transcriptional regulator
ADZ28_RS13505	COG4983	Phage plasmid primase, P4 family domain protein
ADZ28_RS13515	COG1204	response to ionizing radiation
ADZ28_RS13525	COG1479	Protein of unknown function DUF262
ADZ28_RS13540	COG3596	GTP binding
ADZ28_RS13550	COG2378	regulation of single-species biofilm formation
ADZ28_RS13590	COG2003	Belongs to the UPF0758 family
ADZ28_RS13605	COG3468	outer membrane autotransporter barrel domain protein
ADZ28_RS13630	COG0366	Alpha amylase catalytic
ADZ28_RS13635	COG0366	Alpha amylase catalytic
ADZ28_RS13640	COG0366	Alpha amylase catalytic
ADZ28_RS13650	COG0579	oxidoreductase
ADZ28_RS13655	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS13660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADZ28_RS13665	COG1113	amino acid transport
ADZ28_RS13670	COG1802	Transcriptional regulator
ADZ28_RS13675	COG1652	LysM domain
ADZ28_RS13680	COG0401	homolog of Blt101
ADZ28_RS13685	COG0640	Transcriptional regulator
ADZ28_RS13690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADZ28_RS13695	COG2916	Histone family protein nucleoid-structuring protein H-NS
ADZ28_RS13710	COG4575	ribosome binding
ADZ28_RS13715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADZ28_RS13725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADZ28_RS13730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADZ28_RS13735	COG4175	Glycine betaine
ADZ28_RS13740	COG4176	ABC-type proline glycine betaine transport system permease component
ADZ28_RS13745	COG2113	Glycine betaine
ADZ28_RS13755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADZ28_RS13765	COG1846	Transcriptional regulator
ADZ28_RS13770	COG1566	PFAM secretion protein HlyD family protein
ADZ28_RS13775	COG2814	Major facilitator Superfamily
ADZ28_RS13790	COG1238	metal cluster binding
ADZ28_RS13795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADZ28_RS13825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ADZ28_RS13850	COG1546	Belongs to the CinA family
ADZ28_RS13855	COG2951	lytic endotransglycosylase activity
ADZ28_RS13860	COG3730	PTS system glucitol sorbitol-specific
ADZ28_RS13865	COG3732	PTS system glucitol sorbitol-specific
ADZ28_RS13870	COG3731	PTS system glucitol sorbitol-specific IIA component
ADZ28_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS13880	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS13885	COG1349	DNA-binding transcription factor activity
ADZ28_RS13890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ADZ28_RS13890	COG0517	IMP dehydrogenase activity
ADZ28_RS13910	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADZ28_RS13915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS13920	COG1609	Transcriptional regulator
ADZ28_RS13925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS13925	COG1263	PTS System
ADZ28_RS13930	COG2723	6-phospho-beta-galactosidase activity
ADZ28_RS13935	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADZ28_RS13945	COG3260	NADH ubiquinone oxidoreductase 20
ADZ28_RS13950	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADZ28_RS13955	COG3261	NADH dehydrogenase
ADZ28_RS13955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ADZ28_RS13960	COG0650	Formate hydrogenlyase subunit 4
ADZ28_RS13965	COG0651	ATP synthesis coupled electron transport
ADZ28_RS13970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS13985	COG0375	protein maturation
ADZ28_RS13990	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADZ28_RS13995	COG0298	carbon dioxide binding
ADZ28_RS14000	COG0409	Hydrogenase expression formation protein
ADZ28_RS14005	COG0309	Hydrogenase expression formation protein (HypE)
ADZ28_RS14010	COG3604	Transcriptional regulator
ADZ28_RS14025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADZ28_RS14030	COG1349	DNA-binding transcription factor activity
ADZ28_RS14035	COG2084	Dehydrogenase
ADZ28_RS14040	COG3395	kinase activity
ADZ28_RS14045	COG0235	Class ii aldolase
ADZ28_RS14050	COG3622	Belongs to the hyi family
ADZ28_RS14055	COG2610	gluconate transmembrane transporter activity
ADZ28_RS14060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADZ28_RS14065	COG1388	LysM domain
ADZ28_RS14065	COG4942	peptidase
ADZ28_RS14120	COG2234	aminopeptidase activity
ADZ28_RS14125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADZ28_RS14130	COG1518	maintenance of DNA repeat elements
ADZ28_RS14145	COG1857	crispr-associated protein
ADZ28_RS14160	COG1203	CRISPR-associated helicase, Cas3
ADZ28_RS14175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ADZ28_RS14180	COG0720	synthase
ADZ28_RS14185	COG0644	oxidoreductase
ADZ28_RS14190	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ADZ28_RS14195	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ADZ28_RS14200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADZ28_RS14205	COG2086	electron transfer activity
ADZ28_RS14210	COG0477	Major facilitator Superfamily
ADZ28_RS14215	COG0277	FAD linked oxidase domain protein
ADZ28_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS14225	COG2223	nitrite transmembrane transporter activity
ADZ28_RS14230	COG1070	Carbohydrate kinase
ADZ28_RS14235	COG0602	queuosine metabolic process
ADZ28_RS14245	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ADZ28_RS14260	COG3956	TIGRFAM MazG family protein
ADZ28_RS14265	COG2337	Toxic component of a toxin-antitoxin (TA) module
ADZ28_RS14270	COG2336	PFAM SpoVT AbrB
ADZ28_RS14275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADZ28_RS14280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADZ28_RS14285	COG2205	protein histidine kinase activity
ADZ28_RS14285	COG3437	response regulator, receiver
ADZ28_RS14285	COG3850	Histidine kinase
ADZ28_RS14285	COG4999	Histidine kinase
ADZ28_RS14290	COG4948	Mandelate Racemase Muconate Lactonizing
ADZ28_RS14295	COG4948	Mandelate Racemase Muconate Lactonizing
ADZ28_RS14300	COG2271	Major facilitator Superfamily
ADZ28_RS14305	COG0716	FMN binding
ADZ28_RS14310	COG0564	pseudouridine synthase activity
ADZ28_RS14315	COG3098	single-species biofilm formation
ADZ28_RS14335	COG1611	Belongs to the LOG family
ADZ28_RS14340	COG0814	amino acid
ADZ28_RS14345	COG1760	l-serine dehydratase
ADZ28_RS14355	COG1454	alcohol dehydrogenase
ADZ28_RS14360	COG0235	Class ii aldolase
ADZ28_RS14365	COG0738	Major facilitator superfamily
ADZ28_RS14375	COG1070	Carbohydrate kinase
ADZ28_RS14385	COG1349	DNA-binding transcription factor activity
ADZ28_RS14395	COG2363	Small membrane protein
ADZ28_RS14400	COG0583	DNA-binding transcription factor activity
ADZ28_RS14410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADZ28_RS14415	COG2166	iron-sulfur cluster assembly
ADZ28_RS14420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADZ28_RS14425	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ADZ28_RS14445	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADZ28_RS14450	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ADZ28_RS14450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADZ28_RS14455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADZ28_RS14460	COG1074	ATP-dependent DNA helicase activity
ADZ28_RS14465	COG1025	Belongs to the peptidase M16 family
ADZ28_RS14470	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ADZ28_RS14475	COG4967	type IV pilus modification protein PilV
ADZ28_RS14485	COG4795	General secretion pathway protein
ADZ28_RS14490	COG2165	general secretion pathway protein
ADZ28_RS14505	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ADZ28_RS14530	COG0861	Integral membrane protein TerC family
ADZ28_RS14540	COG0667	Aldo Keto reductase
ADZ28_RS14555	COG1609	Transcriptional regulator
ADZ28_RS14565	COG0583	DNA-binding transcription factor activity
ADZ28_RS14570	COG1794	racemase activity, acting on amino acids and derivatives
ADZ28_RS14575	COG2814	Major facilitator Superfamily
ADZ28_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS14590	COG0183	Belongs to the thiolase family
ADZ28_RS14595	COG0814	amino acid
ADZ28_RS14600	COG2771	luxR family
ADZ28_RS14605	COG3710	Transcriptional regulator
ADZ28_RS14625	COG0457	Tetratricopeptide repeat
ADZ28_RS14630	COG3710	Transcriptional regulator
ADZ28_RS14630	COG0457	Tetratricopeptide repeat
ADZ28_RS14645	COG2197	response regulator
ADZ28_RS14650	COG2197	response regulator
ADZ28_RS14680	COG3387	PFAM Glycoside hydrolase 15-related
ADZ28_RS14685	COG3387	PFAM Glycoside hydrolase 15-related
ADZ28_RS14695	COG4942	peptidase
ADZ28_RS14700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ADZ28_RS14705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ADZ28_RS14710	COG2080	2 iron, 2 sulfur cluster binding
ADZ28_RS14715	COG3829	transcription factor binding
ADZ28_RS14720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADZ28_RS14725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADZ28_RS14730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADZ28_RS14740	COG0549	Belongs to the carbamate kinase family
ADZ28_RS14745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ADZ28_RS14745	COG3608	succinylglutamate desuccinylase aspartoacylase
ADZ28_RS14750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADZ28_RS14755	COG2068	MobA-Related Protein
ADZ28_RS14760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS14760	COG0493	'glutamate synthase
ADZ28_RS14765	COG0402	S-adenosylhomocysteine deaminase activity
ADZ28_RS14770	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ADZ28_RS14775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ADZ28_RS14775	COG2080	2 iron, 2 sulfur cluster binding
ADZ28_RS14780	COG2233	PERMEase
ADZ28_RS14785	COG0402	S-adenosylhomocysteine deaminase activity
ADZ28_RS14790	COG2252	PERMEase
ADZ28_RS14795	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS14800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS14800	COG0493	'glutamate synthase
ADZ28_RS14810	COG2233	PERMEase
ADZ28_RS14825	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADZ28_RS14835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADZ28_RS14840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADZ28_RS14845	COG4974	Belongs to the 'phage' integrase family
ADZ28_RS14850	COG0716	FMN binding
ADZ28_RS14860	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ADZ28_RS14870	COG1272	protein, Hemolysin III
ADZ28_RS14880	COG2723	6-phospho-beta-galactosidase activity
ADZ28_RS14885	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS14905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADZ28_RS14910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADZ28_RS14915	COG0006	proline dipeptidase activity
ADZ28_RS14930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADZ28_RS14935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADZ28_RS14955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADZ28_RS14955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADZ28_RS14960	COG1703	isobutyryl-CoA mutase activity
ADZ28_RS14965	COG1024	Enoyl-CoA hydratase
ADZ28_RS14970	COG0427	acetyl-CoA hydrolase
ADZ28_RS14975	COG0583	DNA-binding transcription factor activity
ADZ28_RS14980	COG2968	Membrane
ADZ28_RS14985	COG1279	arginine transmembrane transporter activity
ADZ28_RS14990	COG0668	transmembrane transport
ADZ28_RS14995	COG0191	fructose-bisphosphate aldolase activity
ADZ28_RS15010	COG1072	(Pantothenic acid kinase))
ADZ28_RS15015	COG3722	fumarate hydratase activity
ADZ28_RS15020	COG1494	fructose-1,6-bisphosphatase
ADZ28_RS15025	COG1063	alcohol dehydrogenase
ADZ28_RS15030	COG2213	PTS system mannitol-specific
ADZ28_RS15035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS15040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADZ28_RS15045	COG0501	Belongs to the peptidase M48B family
ADZ28_RS15055	COG1166	arginine decarboxylase activity
ADZ28_RS15080	COG2814	Major facilitator Superfamily
ADZ28_RS15090	COG2356	endonuclease I
ADZ28_RS15095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADZ28_RS15100	COG0189	ligase activity
ADZ28_RS15115	COG2805	Type II/IV secretion system protein
ADZ28_RS15120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADZ28_RS15125	COG0762	integral membrane protein
ADZ28_RS15135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADZ28_RS15140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADZ28_RS15150	COG0252	asparaginase activity
ADZ28_RS15165	COG3171	Protein conserved in bacteria
ADZ28_RS15175	COG1194	a g-specific adenine glycosylase
ADZ28_RS15190	COG2211	Major facilitator Superfamily
ADZ28_RS15195	COG1982	Orn Lys Arg decarboxylase major
ADZ28_RS15200	COG1811	Na channel or pump
ADZ28_RS15210	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ADZ28_RS15220	COG3031	protein transport across the cell outer membrane
ADZ28_RS15230	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADZ28_RS15235	COG3064	Membrane
ADZ28_RS15245	COG1620	l-lactate permease
ADZ28_RS15250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ADZ28_RS15255	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ADZ28_RS15260	COG0247	lactate metabolic process
ADZ28_RS15265	COG0277	FAD linked oxidase domain protein
ADZ28_RS15270	COG0277	FAD linked oxidase domain protein
ADZ28_RS15275	COG2186	Transcriptional regulator
ADZ28_RS15280	COG0456	acetyltransferase
ADZ28_RS15290	COG2244	polysaccharide biosynthetic process
ADZ28_RS15295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADZ28_RS15300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADZ28_RS15305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADZ28_RS15310	COG0306	phosphate transporter
ADZ28_RS15315	COG0754	glutathionylspermidine amidase activity
ADZ28_RS15320	COG0625	glutathione transferase activity
ADZ28_RS15325	COG0298	carbon dioxide binding
ADZ28_RS15335	COG1773	rubredoxin
ADZ28_RS15340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADZ28_RS15345	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ADZ28_RS15350	COG5557	Pfam Polysulphide reductase, NrfD
ADZ28_RS15355	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS15360	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADZ28_RS15380	COG0667	Aldo Keto reductase
ADZ28_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS15395	COG0848	biopolymer transport protein
ADZ28_RS15400	COG0811	peptide transport
ADZ28_RS15410	COG0626	cystathionine gamma-synthase activity
ADZ28_RS15415	COG0586	Pfam SNARE associated Golgi protein
ADZ28_RS15420	COG2207	Transcriptional regulator
ADZ28_RS15430	COG1979	alcohol dehydrogenase
ADZ28_RS15435	COG0656	L-ascorbic acid biosynthetic process
ADZ28_RS15445	COG4238	major outer membrane lipoprotein
ADZ28_RS15450	COG1032	radical SAM domain protein
ADZ28_RS15460	COG0204	Acyl-transferase
ADZ28_RS15465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADZ28_RS15470	COG4166	transmembrane transport
ADZ28_RS15475	COG2944	sequence-specific DNA binding
ADZ28_RS15485	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ADZ28_RS15490	COG3111	PFAM Bacterial OB fold (BOF) protein
ADZ28_RS15495	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS15500	COG0642	Histidine kinase
ADZ28_RS15510	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADZ28_RS15515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ADZ28_RS15520	COG0187	DNA topoisomerase II activity
ADZ28_RS15525	COG3150	esterase
ADZ28_RS15530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ADZ28_RS15535	COG3151	Protein conserved in bacteria
ADZ28_RS15540	COG0494	nUDIX hydrolase
ADZ28_RS15545	COG1538	Outer membrane efflux protein
ADZ28_RS15560	COG0754	glutathionylspermidine amidase activity
ADZ28_RS15565	COG3384	dioxygenase
ADZ28_RS15585	COG2960	long-chain fatty acid transporting porin activity
ADZ28_RS15590	COG3539	Fimbrial protein
ADZ28_RS15605	COG3188	usher protein
ADZ28_RS15610	COG3121	Chaperone
ADZ28_RS15615	COG3539	Fimbrial protein
ADZ28_RS15625	COG1585	Membrane protein implicated in regulation of membrane protease activity
ADZ28_RS15630	COG2268	Band 7 protein
ADZ28_RS15655	COG3025	triphosphatase activity
ADZ28_RS15665	COG4991	sh3 domain protein
ADZ28_RS15680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ADZ28_RS15690	COG0583	DNA-binding transcription factor activity
ADZ28_RS15695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADZ28_RS15705	COG0471	metal ion transport
ADZ28_RS15715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ADZ28_RS15720	COG0358	DNA primase activity
ADZ28_RS15725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADZ28_RS15740	COG2375	cellular response to nickel ion
ADZ28_RS15745	COG1695	Transcriptional regulator
ADZ28_RS15750	COG0840	transmembrane signaling receptor activity
ADZ28_RS15760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADZ28_RS15765	COG1609	Transcriptional regulator
ADZ28_RS15770	COG3250	beta-galactosidase activity
ADZ28_RS15775	COG2731	YhcH YjgK YiaL family protein
ADZ28_RS15780	COG0531	amino acid
ADZ28_RS15790	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ADZ28_RS15790	COG3408	Glycogen debranching enzyme
ADZ28_RS15795	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADZ28_RS15795	COG1902	pentaerythritol trinitrate reductase activity
ADZ28_RS15800	COG5499	transcription regulator containing HTH domain
ADZ28_RS15805	COG4680	protein conserved in bacteria
ADZ28_RS15820	COG1451	nucleotide metabolic process
ADZ28_RS15825	COG2949	membrane
ADZ28_RS15830	COG0673	inositol 2-dehydrogenase activity
ADZ28_RS15835	COG0861	Integral membrane protein TerC family
ADZ28_RS15840	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ADZ28_RS15850	COG2721	sulfolactate sulfo-lyase activity
ADZ28_RS15860	COG2271	Major facilitator Superfamily
ADZ28_RS15865	COG2186	Transcriptional regulator
ADZ28_RS15870	COG0586	Pfam SNARE associated Golgi protein
ADZ28_RS15880	COG1422	Protein of unknown function (DUF1090)
ADZ28_RS15885	COG4575	ribosome binding
ADZ28_RS15890	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ADZ28_RS15900	COG2259	Doxx family
ADZ28_RS15905	COG0435	Glutathione S-transferase
ADZ28_RS15910	COG3152	Membrane
ADZ28_RS15915	COG3152	Membrane
ADZ28_RS15920	COG0583	DNA-binding transcription factor activity
ADZ28_RS15925	COG1741	Belongs to the pirin family
ADZ28_RS15940	COG0814	amino acid
ADZ28_RS15945	COG1760	l-serine dehydratase
ADZ28_RS15950	COG0251	oxidation-reduction process
ADZ28_RS15955	COG1882	Formate acetyltransferase
ADZ28_RS15960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADZ28_RS15970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADZ28_RS15975	COG0583	DNA-binding transcription factor activity
ADZ28_RS15995	COG1929	Belongs to the glycerate kinase type-1 family
ADZ28_RS16000	COG2084	Dehydrogenase
ADZ28_RS16010	COG2271	Major facilitator Superfamily
ADZ28_RS16015	COG2721	sulfolactate sulfo-lyase activity
ADZ28_RS16020	COG2002	toxin-antitoxin pair type II binding
ADZ28_RS16030	COG1349	DNA-binding transcription factor activity
ADZ28_RS16040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS16050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ADZ28_RS16055	COG2222	sugar isomerase
ADZ28_RS16065	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS16070	COG3715	PTS system
ADZ28_RS16075	COG3716	PTS system mannose fructose sorbose family IID component
ADZ28_RS16080	COG0363	glucosamine-6-phosphate deaminase activity
ADZ28_RS16085	COG3539	Fimbrial protein
ADZ28_RS16090	COG3121	Chaperone
ADZ28_RS16095	COG3188	usher protein
ADZ28_RS16100	COG3539	Fimbrial protein
ADZ28_RS16105	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADZ28_RS16110	COG3107	peptidoglycan biosynthetic process
ADZ28_RS16125	COG2823	Periplasmic or secreted lipoprotein
ADZ28_RS16130	COG0701	Predicted permease
ADZ28_RS16135	COG0702	epimerase
ADZ28_RS16140	COG0693	protein deglycase activity
ADZ28_RS16155	COG3153	acetyltransferase
ADZ28_RS16160	COG3154	lipid carrier protein
ADZ28_RS16165	COG0826	peptidase U32
ADZ28_RS16170	COG0826	peptidase U32
ADZ28_RS16175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADZ28_RS16180	COG0814	amino acid
ADZ28_RS16190	COG0513	Belongs to the DEAD box helicase family
ADZ28_RS16225	COG0195	Participates in both transcription termination and antitermination
ADZ28_RS16245	COG2194	sulfuric ester hydrolase activity
ADZ28_RS16255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADZ28_RS16265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADZ28_RS16270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADZ28_RS16280	COG1534	Rna-binding protein
ADZ28_RS16285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADZ28_RS16290	COG2027	D-alanyl-D-alanine carboxypeptidase
ADZ28_RS16300	COG0697	spore germination
ADZ28_RS16315	COG0142	geranyltranstransferase activity
ADZ28_RS16320	COG3423	Transcriptional regulator
ADZ28_RS16330	COG5007	Belongs to the BolA IbaG family
ADZ28_RS16335	COG3113	response to antibiotic
ADZ28_RS16340	COG2854	intermembrane phospholipid transfer
ADZ28_RS16345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ADZ28_RS16350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADZ28_RS16355	COG1127	ABC transporter
ADZ28_RS16360	COG0530	calcium, potassium:sodium antiporter activity
ADZ28_RS16365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ADZ28_RS16365	COG0517	IMP dehydrogenase activity
ADZ28_RS16370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ADZ28_RS16375	COG3117	lipopolysaccharide transmembrane transporter activity
ADZ28_RS16380	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ADZ28_RS16385	COG1137	ATPase activity
ADZ28_RS16390	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ADZ28_RS16395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADZ28_RS16410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS16415	COG0515	serine threonine protein kinase
ADZ28_RS16425	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ADZ28_RS16430	COG0784	Response regulator, receiver
ADZ28_RS16430	COG5002	protein histidine kinase activity
ADZ28_RS16430	COG2198	Histidine kinase
ADZ28_RS16435	COG1242	4 iron, 4 sulfur cluster binding
ADZ28_RS16440	COG0069	glutamate synthase activity
ADZ28_RS16440	COG0067	glutamate synthase
ADZ28_RS16440	COG0070	glutamate synthase
ADZ28_RS16445	COG0493	'glutamate synthase
ADZ28_RS16450	COG3539	Fimbrial protein
ADZ28_RS16455	COG3121	Chaperone
ADZ28_RS16460	COG3188	usher protein
ADZ28_RS16480	COG3539	Fimbrial protein
ADZ28_RS16485	COG4804	nuclease activity
ADZ28_RS16490	COG2731	YhcH YjgK YiaL family protein
ADZ28_RS16520	COG3069	C4-dicarboxylate transmembrane transporter activity
ADZ28_RS16525	COG2969	positive regulation of protein catabolic process
ADZ28_RS16530	COG0625	glutathione transferase activity
ADZ28_RS16545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ADZ28_RS16550	COG3105	Protein conserved in bacteria
ADZ28_RS16555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADZ28_RS16560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADZ28_RS16580	COG2732	(Barnase) inhibitor
ADZ28_RS16600	COG0583	DNA-binding transcription factor activity
ADZ28_RS16605	COG0312	modulator of DNA gyrase
ADZ28_RS16610	COG3164	Protein of unknown function
ADZ28_RS16615	COG1530	ribonuclease E activity
ADZ28_RS16620	COG0424	maF-like protein
ADZ28_RS16625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ADZ28_RS16630	COG1792	Involved in formation and maintenance of cell shape
ADZ28_RS16635	COG1077	Cell shape determining protein MreB Mrl
ADZ28_RS16645	COG2200	EAL domain
ADZ28_RS16645	COG2199	diguanylate cyclase activity
ADZ28_RS16650	COG0604	alcohol dehydrogenase
ADZ28_RS16670	COG0511	ligase activity, forming carbon-carbon bonds
ADZ28_RS16675	COG0439	Biotin carboxylase
ADZ28_RS16680	COG3924	membrane
ADZ28_RS16685	COG4145	pantothenate transmembrane transporter activity
ADZ28_RS16695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADZ28_RS16705	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ADZ28_RS16715	COG1309	transcriptional regulator
ADZ28_RS16720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADZ28_RS16725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADZ28_RS16740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADZ28_RS16745	COG4597	amino acid ABC transporter
ADZ28_RS16750	COG0765	amino acid transport
ADZ28_RS16755	COG1126	abc transporter atp-binding protein
ADZ28_RS16795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ADZ28_RS16815	COG0551	DNA topoisomerase type I activity
ADZ28_RS16825	COG0758	DNA mediated transformation
ADZ28_RS16845	COG0569	domain protein
ADZ28_RS16855	COG3036	rescue of stalled ribosome
ADZ28_RS16860	COG0789	Transcriptional regulator
ADZ28_RS16900	COG0201	protein transport
ADZ28_RS16990	COG0089	rRNA binding
ADZ28_RS17015	COG3267	Type II secretory pathway component ExeA
ADZ28_RS17015	COG3409	Peptidoglycan-binding domain 1 protein
ADZ28_RS17020	COG3031	protein transport across the cell outer membrane
ADZ28_RS17025	COG1450	Type ii and iii secretion system protein
ADZ28_RS17030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ADZ28_RS17035	COG1459	type II secretion system
ADZ28_RS17040	COG2165	general secretion pathway protein
ADZ28_RS17045	COG2165	general secretion pathway protein
ADZ28_RS17050	COG2165	general secretion pathway protein
ADZ28_RS17055	COG4795	General secretion pathway protein
ADZ28_RS17060	COG3156	type II secretion system protein K
ADZ28_RS17065	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ADZ28_RS17070	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ADZ28_RS17075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADZ28_RS17080	COG2193	ferroxidase activity
ADZ28_RS17085	COG2906	2 iron, 2 sulfur cluster binding
ADZ28_RS17090	COG3979	chitinase
ADZ28_RS17130	COG2964	Protein conserved in bacteria
ADZ28_RS17135	COG0545	Peptidyl-prolyl cis-trans isomerase
ADZ28_RS17145	COG1047	Peptidyl-prolyl cis-trans
ADZ28_RS17150	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ADZ28_RS17165	COG0488	(ABC) transporter
ADZ28_RS17170	COG0429	hydrolase of the alpha beta-hydrolase fold
ADZ28_RS17180	COG3954	Phosphoribulokinase
ADZ28_RS17185	COG1765	OsmC-like protein
ADZ28_RS17195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADZ28_RS17200	COG1289	transmembrane transporter activity
ADZ28_RS17205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADZ28_RS17210	COG0512	Glutamine amidotransferase of anthranilate synthase
ADZ28_RS17215	COG2184	nucleotidyltransferase activity
ADZ28_RS17225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADZ28_RS17235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADZ28_RS17240	COG2146	nitrite reductase [NAD(P)H] activity
ADZ28_RS17245	COG2116	formate transmembrane transporter activity
ADZ28_RS17260	COG0531	amino acid
ADZ28_RS17265	COG2222	sugar isomerase
ADZ28_RS17270	COG1082	Xylose isomerase domain protein TIM barrel
ADZ28_RS17275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS17280	COG2188	Transcriptional regulator
ADZ28_RS17285	COG0626	cystathionine gamma-synthase activity
ADZ28_RS17300	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ADZ28_RS17305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ADZ28_RS17310	COG3457	Alanine racemase
ADZ28_RS17320	COG2188	Transcriptional regulator
ADZ28_RS17325	COG0180	Tryptophanyl-tRNA synthetase
ADZ28_RS17330	COG0546	phosphoglycolate phosphatase activity
ADZ28_RS17335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADZ28_RS17340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ADZ28_RS17345	COG3266	domain, Protein
ADZ28_RS17360	COG4796	Type ii and iii secretion system protein
ADZ28_RS17375	COG3166	PFAM Fimbrial assembly family protein
ADZ28_RS17380	COG4972	Pilus assembly protein
ADZ28_RS17385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ADZ28_RS17390	COG0494	nUDIX hydrolase
ADZ28_RS17400	COG1011	Hydrolase
ADZ28_RS17405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ADZ28_RS17415	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ADZ28_RS17440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADZ28_RS17445	COG2183	response to ionizing radiation
ADZ28_RS17450	COG1918	ferrous iron import across plasma membrane
ADZ28_RS17455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADZ28_RS17465	COG5464	transposase or invertase
ADZ28_RS17475	COG1040	competence protein
ADZ28_RS17485	COG2610	gluconate transmembrane transporter activity
ADZ28_RS17490	COG1640	4-alpha-glucanotransferase
ADZ28_RS17495	COG0058	SHG alpha-glucan phosphorylase activity
ADZ28_RS17510	COG1690	Belongs to the RtcB family
ADZ28_RS17515	COG4650	regulator
ADZ28_RS17520	COG1349	DNA-binding transcription factor activity
ADZ28_RS17535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADZ28_RS17540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ADZ28_RS17545	COG0058	SHG alpha-glucan phosphorylase activity
ADZ28_RS17570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADZ28_RS17575	COG2095	MarC family integral membrane protein
ADZ28_RS17580	COG2610	gluconate transmembrane transporter activity
ADZ28_RS17585	COG3265	gluconokinase activity
ADZ28_RS17590	COG1609	Transcriptional regulator
ADZ28_RS17595	COG1741	Belongs to the pirin family
ADZ28_RS17600	COG0673	inositol 2-dehydrogenase activity
ADZ28_RS17605	COG1247	-acetyltransferase
ADZ28_RS17610	COG3157	Type VI secretion system effector, Hcp
ADZ28_RS17630	COG0405	Gamma-glutamyltransferase
ADZ28_RS17640	COG0584	glycerophosphoryl diester phosphodiesterase
ADZ28_RS17645	COG3842	ATPase activity
ADZ28_RS17650	COG0395	ABC-type sugar transport system, permease component
ADZ28_RS17655	COG1175	transmembrane transport
ADZ28_RS17660	COG1653	transport
ADZ28_RS17670	COG0410	ABC transporter
ADZ28_RS17675	COG0411	ABC transporter
ADZ28_RS17680	COG4177	L-phenylalanine transmembrane transporter activity
ADZ28_RS17685	COG0559	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS17690	COG0683	leucine binding
ADZ28_RS17695	COG0456	acetyltransferase
ADZ28_RS17705	COG0683	leucine binding
ADZ28_RS17710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADZ28_RS17715	COG2177	Part of the ABC transporter FtsEX involved in
ADZ28_RS17720	COG2884	Cell division ATP-binding protein ftsE
ADZ28_RS17725	COG0552	protein localization to endoplasmic reticulum
ADZ28_RS17730	COG0742	ribosomal rna small subunit methyltransferase
ADZ28_RS17735	COG3776	membrane
ADZ28_RS17745	COG3714	YhhN family
ADZ28_RS17750	COG2217	Heavy metal translocating P-type atpase
ADZ28_RS17760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ADZ28_RS17770	COG0477	Major facilitator Superfamily
ADZ28_RS17775	COG0628	permease
ADZ28_RS17780	COG2091	lysine biosynthetic process via aminoadipic acid
ADZ28_RS17785	COG0747	negative chemotaxis
ADZ28_RS17790	COG0601	transmembrane transport
ADZ28_RS17795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADZ28_RS17800	COG0444	Belongs to the ABC transporter superfamily
ADZ28_RS17805	COG1124	(ABC) transporter
ADZ28_RS17815	COG3209	COG3209 Rhs family protein
ADZ28_RS17830	COG5433	transposase activity
ADZ28_RS17835	COG0842	Transport permease protein
ADZ28_RS17840	COG1129	ABC transporter
ADZ28_RS17840	COG0842	Transport permease protein
ADZ28_RS17845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADZ28_RS17875	COG2081	HI0933 family
ADZ28_RS17880	COG0306	phosphate transporter
ADZ28_RS17890	COG0589	response to stress
ADZ28_RS17895	COG3104	oligopeptide transport
ADZ28_RS17905	COG0339	signal peptide processing
ADZ28_RS17910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ADZ28_RS17915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADZ28_RS17930	COG0640	Transcriptional regulator
ADZ28_RS17935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADZ28_RS17940	COG1393	Belongs to the ArsC family
ADZ28_RS17960	COG3065	identical protein binding
ADZ28_RS17965	COG2197	response regulator
ADZ28_RS17970	COG1285	pathogenesis
ADZ28_RS17985	COG3247	response to pH
ADZ28_RS17990	COG2771	luxR family
ADZ28_RS18000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADZ28_RS18005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADZ28_RS18010	COG2207	Transcriptional regulator
ADZ28_RS18015	COG2207	Transcriptional regulator
ADZ28_RS18020	COG0076	glutamate decarboxylase activity
ADZ28_RS18025	COG1858	cytochrome C peroxidase
ADZ28_RS18035	COG2197	response regulator
ADZ28_RS18040	COG0583	DNA-binding transcription factor activity
ADZ28_RS18045	COG1295	ribonuclease BN
ADZ28_RS18050	COG0477	Major facilitator Superfamily
ADZ28_RS18055	COG2982	Protein involved in outer membrane biogenesis
ADZ28_RS18060	COG2982	Protein involved in outer membrane biogenesis
ADZ28_RS18065	COG2200	EAL domain
ADZ28_RS18075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS18080	COG0612	Peptidase, M16
ADZ28_RS18090	COG2200	EAL domain
ADZ28_RS18090	COG2199	diguanylate cyclase activity
ADZ28_RS18095	COG3118	belongs to the thioredoxin family
ADZ28_RS18095	COG0457	Tetratricopeptide repeat
ADZ28_RS18100	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ADZ28_RS18105	COG1215	transferase activity, transferring glycosyl groups
ADZ28_RS18110	COG1215	transferase activity, transferring glycosyl groups
ADZ28_RS18135	COG2194	sulfuric ester hydrolase activity
ADZ28_RS18150	COG0814	amino acid
ADZ28_RS18155	COG4608	Belongs to the ABC transporter superfamily
ADZ28_RS18160	COG0444	Belongs to the ABC transporter superfamily
ADZ28_RS18165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADZ28_RS18170	COG0601	transmembrane transport
ADZ28_RS18180	COG0747	negative chemotaxis
ADZ28_RS18195	COG2194	sulfuric ester hydrolase activity
ADZ28_RS18200	COG2223	nitrite transmembrane transporter activity
ADZ28_RS18205	COG5571	outer membrane autotransporter
ADZ28_RS18210	COG2818	Glycosylase
ADZ28_RS18215	COG0456	acetyltransferase
ADZ28_RS18220	COG0243	molybdopterin cofactor binding
ADZ28_RS18225	COG2885	chlorophyll binding
ADZ28_RS18240	COG2944	sequence-specific DNA binding
ADZ28_RS18245	COG1278	Cold shock
ADZ28_RS18255	COG2963	transposase activity
ADZ28_RS18260	COG2801	Transposase and inactivated derivatives
ADZ28_RS18280	COG3274	enterobacterial common antigen metabolic process
ADZ28_RS18285	COG4682	membrane
ADZ28_RS18290	COG4682	membrane
ADZ28_RS18295	COG1070	Carbohydrate kinase
ADZ28_RS18305	COG4213	ABC transporter substrate-binding protein
ADZ28_RS18310	COG1129	ABC transporter
ADZ28_RS18315	COG4214	carbohydrate transport
ADZ28_RS18320	COG1609	Transcriptional regulator
ADZ28_RS18320	COG2207	Transcriptional regulator
ADZ28_RS18325	COG2992	FlgJ-related protein
ADZ28_RS18330	COG0366	Alpha amylase catalytic
ADZ28_RS18335	COG3977	Valine--pyruvate aminotransferase
ADZ28_RS18345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADZ28_RS18350	COG1414	Transcriptional regulator
ADZ28_RS18360	COG2731	YhcH YjgK YiaL family protein
ADZ28_RS18365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADZ28_RS18370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADZ28_RS18375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ADZ28_RS18380	COG1070	Carbohydrate kinase
ADZ28_RS18385	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ADZ28_RS18390	COG3623	hexulose-6-phosphate isomerase
ADZ28_RS18395	COG0235	Class ii aldolase
ADZ28_RS18400	COG3713	MltA-interacting MipA family protein
ADZ28_RS18405	COG0583	DNA-binding transcription factor activity
ADZ28_RS18410	COG1566	PFAM secretion protein HlyD family protein
ADZ28_RS18425	COG1012	belongs to the aldehyde dehydrogenase family
ADZ28_RS18430	COG1454	alcohol dehydrogenase
ADZ28_RS18435	COG3276	selenocysteine insertion sequence binding
ADZ28_RS18445	COG0625	glutathione transferase activity
ADZ28_RS18450	COG3209	COG3209 Rhs family protein
ADZ28_RS18455	COG1413	lyase activity
ADZ28_RS18460	COG3209	COG3209 Rhs family protein
ADZ28_RS18465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ADZ28_RS18475	COG1566	PFAM secretion protein HlyD family protein
ADZ28_RS18485	COG2213	PTS system mannitol-specific
ADZ28_RS18485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS18495	COG3722	fumarate hydratase activity
ADZ28_RS18510	COG1620	l-lactate permease
ADZ28_RS18515	COG2186	Transcriptional regulator
ADZ28_RS18525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ADZ28_RS18530	COG1045	serine acetyltransferase
ADZ28_RS18545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ADZ28_RS18550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADZ28_RS18555	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ADZ28_RS18560	COG4942	peptidase
ADZ28_RS18565	COG2861	carbohydrate metabolic process
ADZ28_RS18570	COG1216	Glycosyl transferase, family 2
ADZ28_RS18580	COG0156	8-amino-7-oxononanoate synthase activity
ADZ28_RS18595	COG0859	PFAM glycosyl transferase family 9
ADZ28_RS18600	COG0859	PFAM glycosyl transferase family 9
ADZ28_RS18605	COG3307	-O-antigen
ADZ28_RS18610	COG0859	PFAM glycosyl transferase family 9
ADZ28_RS18620	COG3642	lipopolysaccharide core region biosynthetic process
ADZ28_RS18625	COG1442	glycosyl transferase family 8
ADZ28_RS18630	COG1442	glycosyl transferase family 8
ADZ28_RS18635	COG0438	transferase activity, transferring glycosyl groups
ADZ28_RS18640	COG0438	transferase activity, transferring glycosyl groups
ADZ28_RS18640	COG4641	Protein conserved in bacteria
ADZ28_RS18645	COG0515	serine threonine protein kinase
ADZ28_RS18650	COG0438	transferase activity, transferring glycosyl groups
ADZ28_RS18655	COG0859	PFAM glycosyl transferase family 9
ADZ28_RS18660	COG1519	Transferase
ADZ28_RS18690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADZ28_RS18695	COG0756	dUTP diphosphatase activity
ADZ28_RS18715	COG1561	YicC-like family, N-terminal region
ADZ28_RS18720	COG3645	SOS response
ADZ28_RS18725	COG2860	membrane
ADZ28_RS18735	COG0194	GDP metabolic process
ADZ28_RS18745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADZ28_RS18750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADZ28_RS18755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADZ28_RS18760	COG0786	glutamate:sodium symporter activity
ADZ28_RS18765	COG2233	PERMEase
ADZ28_RS18770	COG2982	Protein involved in outer membrane biogenesis
ADZ28_RS18775	COG1501	Belongs to the glycosyl hydrolase 31 family
ADZ28_RS18780	COG2211	Major facilitator Superfamily
ADZ28_RS18795	COG2814	Major facilitator Superfamily
ADZ28_RS18800	COG0697	spore germination
ADZ28_RS18805	COG1464	Belongs to the NlpA lipoprotein family
ADZ28_RS18830	COG2252	PERMEase
ADZ28_RS18840	COG2271	Major facilitator Superfamily
ADZ28_RS18845	COG2271	Major facilitator Superfamily
ADZ28_RS18850	COG3851	Histidine kinase
ADZ28_RS18855	COG2197	response regulator
ADZ28_RS18860	COG0440	acetolactate synthase activity
ADZ28_RS18865	COG0028	Belongs to the TPP enzyme family
ADZ28_RS18890	COG2814	Major facilitator Superfamily
ADZ28_RS18895	COG0641	radical SAM
ADZ28_RS18905	COG2149	membrane
ADZ28_RS18915	COG3119	arylsulfatase activity
ADZ28_RS18920	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADZ28_RS18925	COG2207	Transcriptional regulator
ADZ28_RS18935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS18935	COG1263	PTS System
ADZ28_RS18940	COG1263	PTS System
ADZ28_RS18945	COG2188	Transcriptional regulator
ADZ28_RS18965	COG5645	(Lipo)protein
ADZ28_RS18970	COG0823	Involved in the tonB-independent uptake of proteins
ADZ28_RS18975	COG0644	oxidoreductase
ADZ28_RS18980	COG2271	Major facilitator Superfamily
ADZ28_RS18990	COG0800	Aldolase
ADZ28_RS18995	COG3734	2-keto-3-deoxy-galactonokinase
ADZ28_RS19000	COG2186	Transcriptional regulator
ADZ28_RS19010	COG0561	phosphatase activity
ADZ28_RS19015	COG3753	Protein conserved in bacteria
ADZ28_RS19025	COG0187	DNA topoisomerase II activity
ADZ28_RS19035	COG0592	DNA-directed DNA polymerase activity
ADZ28_RS19080	COG0814	amino acid
ADZ28_RS19090	COG0814	amino acid
ADZ28_RS19105	COG2091	lysine biosynthetic process via aminoadipic acid
ADZ28_RS19110	COG0431	NADPH-dependent FMN reductase
ADZ28_RS19115	COG2252	PERMEase
ADZ28_RS19120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADZ28_RS19130	COG3196	Protein conserved in bacteria
ADZ28_RS19135	COG0363	glucosamine-6-phosphate deaminase activity
ADZ28_RS19140	COG2382	esterase
ADZ28_RS19150	COG2723	6-phospho-beta-galactosidase activity
ADZ28_RS19155	COG1263	PTS System
ADZ28_RS19155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS19155	COG2190	(PTS) system
ADZ28_RS19160	COG3711	transcriptional antiterminator
ADZ28_RS19165	COG0704	Plays a role in the regulation of phosphate uptake
ADZ28_RS19170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADZ28_RS19175	COG0581	inorganic phosphate transmembrane transporter activity
ADZ28_RS19180	COG0573	inorganic phosphate transmembrane transporter activity
ADZ28_RS19185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ADZ28_RS19190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADZ28_RS19240	COG3312	ion transport
ADZ28_RS19255	COG0716	FMN binding
ADZ28_RS19260	COG1522	sequence-specific DNA binding
ADZ28_RS19290	COG1129	ABC transporter
ADZ28_RS19295	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS19300	COG1879	ABC-type sugar transport system periplasmic component
ADZ28_RS19305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS19315	COG0477	Major facilitator Superfamily
ADZ28_RS19320	COG2186	Transcriptional regulator
ADZ28_RS19360	COG3085	chromosome segregation
ADZ28_RS19365	COG0606	chelatase, subunit chli
ADZ28_RS19380	COG3978	acetolactate synthase activity
ADZ28_RS19385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADZ28_RS19395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADZ28_RS19400	COG0583	DNA-binding transcription factor activity
ADZ28_RS19410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADZ28_RS19420	COG0210	DNA helicase
ADZ28_RS19435	COG3118	belongs to the thioredoxin family
ADZ28_RS19445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADZ28_RS19455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADZ28_RS19460	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ADZ28_RS19465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ADZ28_RS19470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADZ28_RS19475	COG1088	dTDP-glucose 4,6-dehydratase activity
ADZ28_RS19480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ADZ28_RS19485	COG0456	acetyltransferase
ADZ28_RS19490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADZ28_RS19495	COG2244	polysaccharide biosynthetic process
ADZ28_RS19515	COG1113	amino acid transport
ADZ28_RS19540	COG0641	radical SAM
ADZ28_RS19545	COG3119	arylsulfatase activity
ADZ28_RS19550	COG3071	HemY protein
ADZ28_RS19555	COG2959	enzyme of heme biosynthesis
ADZ28_RS19560	COG1587	Uroporphyrinogen-III synthase
ADZ28_RS19570	COG3072	Adenylate cyclase
ADZ28_RS19580	COG5567	small periplasmic lipoprotein
ADZ28_RS19590	COG3159	Protein conserved in bacteria
ADZ28_RS19600	COG1011	Hydrolase
ADZ28_RS19605	COG0210	DNA helicase
ADZ28_RS19610	COG3698	Phosphodiester glycosidase
ADZ28_RS19620	COG0598	Magnesium transport protein CorA
ADZ28_RS19635	COG2962	Rard protein
ADZ28_RS19640	COG2050	protein possibly involved in aromatic compounds catabolism
ADZ28_RS19645	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ADZ28_RS19650	COG0514	ATP-dependent DNA helicase (RecQ)
ADZ28_RS19655	COG1280	lysine exporter protein (LysE YggA)
ADZ28_RS19660	COG1280	lysine exporter protein (LysE YggA)
ADZ28_RS19665	COG2267	carboxylic ester hydrolase activity
ADZ28_RS19670	COG0561	phosphatase activity
ADZ28_RS19675	COG0697	spore germination
ADZ28_RS19680	COG0583	DNA-binding transcription factor activity
ADZ28_RS19690	COG0412	Dienelactone hydrolase
ADZ28_RS19695	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ADZ28_RS19700	COG1322	Protein conserved in bacteria
ADZ28_RS19710	COG3165	ubiquinone biosynthetic process from chorismate
ADZ28_RS19720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADZ28_RS19725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADZ28_RS19730	COG0805	protein transport
ADZ28_RS19735	COG0084	hydrolase, TatD family'
ADZ28_RS19740	COG0250	Participates in transcription elongation, termination and antitermination
ADZ28_RS19745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ADZ28_RS19750	COG0543	2 iron, 2 sulfur cluster binding
ADZ28_RS19755	COG0183	Belongs to the thiolase family
ADZ28_RS19770	COG1739	Uncharacterized protein family UPF0029
ADZ28_RS19775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADZ28_RS19780	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ADZ28_RS19810	COG1763	Mo-molybdopterin cofactor biosynthetic process
ADZ28_RS19815	COG0746	molybdenum cofactor guanylyltransferase activity
ADZ28_RS19820	COG3084	Protein conserved in bacteria
ADZ28_RS19825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ADZ28_RS19830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADZ28_RS19835	COG5339	Protein conserved in bacteria
ADZ28_RS19840	COG0204	Acyl-transferase
ADZ28_RS19850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADZ28_RS19850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADZ28_RS19865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADZ28_RS19875	COG2204	response regulator
ADZ28_RS19880	COG3852	Histidine kinase
ADZ28_RS19885	COG0174	glutamine synthetase
ADZ28_RS19895	COG1217	gtp-binding protein TYPA
ADZ28_RS19900	COG2188	Transcriptional regulator
ADZ28_RS19905	COG1082	Xylose isomerase domain protein TIM barrel
ADZ28_RS19910	COG2271	Major facilitator Superfamily
ADZ28_RS19915	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADZ28_RS19920	COG2211	Major facilitator Superfamily
ADZ28_RS19925	COG2211	Major facilitator Superfamily
ADZ28_RS19930	COG1501	Belongs to the glycosyl hydrolase 31 family
ADZ28_RS19935	COG2017	converts alpha-aldose to the beta-anomer
ADZ28_RS19940	COG2942	2-epimerase
ADZ28_RS19945	COG3684	Belongs to the aldolase LacD family
ADZ28_RS19950	COG2084	Dehydrogenase
ADZ28_RS19955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADZ28_RS19960	COG1349	DNA-binding transcription factor activity
ADZ28_RS19965	COG1011	Hydrolase
ADZ28_RS19980	COG0456	acetyltransferase
ADZ28_RS19985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADZ28_RS19990	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ADZ28_RS20005	COG2864	formate dehydrogenase
ADZ28_RS20010	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS20015	COG0243	molybdopterin cofactor binding
ADZ28_RS20015	COG3383	formate dehydrogenase (NAD+) activity
ADZ28_RS20020	COG0243	molybdopterin cofactor binding
ADZ28_RS20020	COG3383	formate dehydrogenase (NAD+) activity
ADZ28_RS20035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS20035	COG3711	transcriptional antiterminator
ADZ28_RS20040	COG1363	Peptidase, m42
ADZ28_RS20045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS20045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS20050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS20095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADZ28_RS20110	COG2258	MOSC domain
ADZ28_RS20115	COG2205	protein histidine kinase activity
ADZ28_RS20120	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS20125	COG3678	ATP-independent chaperone mediated protein folding
ADZ28_RS20140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ADZ28_RS20160	COG3152	Membrane
ADZ28_RS20165	COG3691	Protein conserved in bacteria
ADZ28_RS20170	COG0589	response to stress
ADZ28_RS20175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADZ28_RS20180	COG1494	fructose-1,6-bisphosphatase
ADZ28_RS20190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADZ28_RS20205	COG1575	Belongs to the MenA family. Type 1 subfamily
ADZ28_RS20220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADZ28_RS20225	COG1609	Transcriptional regulator
ADZ28_RS20230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADZ28_RS20240	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ADZ28_RS20250	COG0626	cystathionine gamma-synthase activity
ADZ28_RS20255	COG0527	aspartate kinase activity
ADZ28_RS20255	COG0460	homoserine dehydrogenase
ADZ28_RS20265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ADZ28_RS20275	COG0697	spore germination
ADZ28_RS20280	COG3738	Protein conserved in bacteria
ADZ28_RS20290	COG0371	Dehydrogenase
ADZ28_RS20295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADZ28_RS20300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS20300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS20300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADZ28_RS20305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS20310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS20315	COG1882	Formate acetyltransferase
ADZ28_RS20320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ADZ28_RS20325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADZ28_RS20330	COG2207	Transcriptional regulator
ADZ28_RS20335	COG2194	sulfuric ester hydrolase activity
ADZ28_RS20355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADZ28_RS20370	COG0583	DNA-binding transcription factor activity
ADZ28_RS20395	COG4206	TonB-dependent receptor
ADZ28_RS20425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADZ28_RS20430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ADZ28_RS20430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ADZ28_RS20470	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADZ28_RS20475	COG0250	Participates in transcription elongation, termination and antitermination
ADZ28_RS20515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADZ28_RS20525	COG2104	thiamine diphosphate biosynthetic process
ADZ28_RS20530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADZ28_RS20565	COG3068	Protein conserved in bacteria
ADZ28_RS20580	COG3678	ATP-independent chaperone mediated protein folding
ADZ28_RS20585	COG4191	Histidine kinase
ADZ28_RS20590	COG2204	response regulator
ADZ28_RS20595	COG0151	Belongs to the GarS family
ADZ28_RS20640	COG0456	acetyltransferase
ADZ28_RS20650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ADZ28_RS20655	COG2224	Isocitrate lyase
ADZ28_RS20670	COG1414	Transcriptional regulator
ADZ28_RS20675	COG1410	methionine synthase
ADZ28_RS20675	COG0646	methionine synthase
ADZ28_RS20680	COG1283	sodium-dependent phosphate transmembrane transporter activity
ADZ28_RS20690	COG1187	pseudouridine synthase activity
ADZ28_RS20700	COG0527	aspartate kinase activity
ADZ28_RS20725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADZ28_RS20745	COG0477	Major facilitator Superfamily
ADZ28_RS20745	COG2814	Major facilitator Superfamily
ADZ28_RS20750	COG3833	ABC-type maltose transport systems, permease component
ADZ28_RS20755	COG1175	transmembrane transport
ADZ28_RS20760	COG2182	Extracellular solute-binding protein
ADZ28_RS20770	COG3842	ATPase activity
ADZ28_RS20790	COG1357	PFAM Pentapeptide repeats (8 copies)
ADZ28_RS20810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADZ28_RS20820	COG0534	Mate efflux family protein
ADZ28_RS20825	COG3237	CsbD-like
ADZ28_RS20830	COG0735	belongs to the Fur family
ADZ28_RS20845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADZ28_RS20855	COG0604	alcohol dehydrogenase
ADZ28_RS20860	COG0305	Participates in initiation and elongation during chromosome replication
ADZ28_RS20865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADZ28_RS20870	COG1448	Aminotransferase
ADZ28_RS20880	COG3700	Belongs to the class B bacterial acid phosphatase family
ADZ28_RS20885	COG0432	Pfam Uncharacterised protein family UPF0047
ADZ28_RS20890	COG2315	Protein conserved in bacteria
ADZ28_RS20895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADZ28_RS20900	COG0629	single-stranded DNA binding
ADZ28_RS20910	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ADZ28_RS20915	COG2207	Transcriptional regulator
ADZ28_RS20920	COG0789	Transcriptional regulator
ADZ28_RS20925	COG2252	PERMEase
ADZ28_RS20930	COG0025	NhaP-type Na H and K H
ADZ28_RS20935	COG1357	PFAM Pentapeptide repeats (8 copies)
ADZ28_RS20945	COG3162	membrane
ADZ28_RS20950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADZ28_RS20960	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ADZ28_RS20965	COG0437	4 iron, 4 sulfur cluster binding
ADZ28_RS20970	COG3301	Polysulphide reductase, NrfD
ADZ28_RS20975	COG1138	Cytochrome C-type biogenesis protein
ADZ28_RS20980	COG3088	subunit of a heme lyase
ADZ28_RS20985	COG4235	cytochrome complex assembly
ADZ28_RS20990	COG1301	dicarboxylic acid transport
ADZ28_RS20995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ADZ28_RS21000	COG3383	formate dehydrogenase (NAD+) activity
ADZ28_RS21005	COG3383	formate dehydrogenase (NAD+) activity
ADZ28_RS21010	COG1538	Outer membrane efflux protein
ADZ28_RS21015	COG1289	transmembrane transporter activity
ADZ28_RS21020	COG1566	PFAM secretion protein HlyD family protein
ADZ28_RS21030	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ADZ28_RS21035	COG1940	carbohydrate kinase activity
ADZ28_RS21040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADZ28_RS21045	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS21050	COG1129	ABC transporter
ADZ28_RS21055	COG1879	ABC-type sugar transport system periplasmic component
ADZ28_RS21060	COG1737	Transcriptional regulator
ADZ28_RS21065	COG0698	ribose 5-phosphate isomerase
ADZ28_RS21075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ADZ28_RS21080	COG0456	acetyltransferase
ADZ28_RS21085	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ADZ28_RS21090	COG3454	Phosphonate metabolism
ADZ28_RS21095	COG4778	phosphonate C-P lyase system protein PhnL
ADZ28_RS21100	COG4107	phosphonate C-P lyase system protein PhnK
ADZ28_RS21105	COG3627	carbon phosphorus lyase activity
ADZ28_RS21110	COG3626	phosphonate metabolism
ADZ28_RS21115	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ADZ28_RS21120	COG3624	Phosphonate C-P lyase system protein PhnG
ADZ28_RS21125	COG2188	Transcriptional regulator
ADZ28_RS21135	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ADZ28_RS21140	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ADZ28_RS21145	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ADZ28_RS21150	COG2824	Alkylphosphonate utilization operon protein PhnA
ADZ28_RS21155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ADZ28_RS21165	COG0477	Major facilitator Superfamily
ADZ28_RS21175	COG0642	Histidine kinase
ADZ28_RS21180	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS21185	COG2194	sulfuric ester hydrolase activity
ADZ28_RS21190	COG0531	amino acid
ADZ28_RS21195	COG2207	Transcriptional regulator
ADZ28_RS21200	COG1982	Orn Lys Arg decarboxylase major
ADZ28_RS21205	COG2169	Transcriptional regulator
ADZ28_RS21215	COG1486	melibiose metabolic process
ADZ28_RS21220	COG2211	Major facilitator Superfamily
ADZ28_RS21225	COG3647	Membrane
ADZ28_RS21230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADZ28_RS21230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ADZ28_RS21235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ADZ28_RS21245	COG4565	transcriptional regulatory protein
ADZ28_RS21250	COG3290	protein histidine kinase activity
ADZ28_RS21255	COG3592	Divergent 4Fe-4S mono-cluster
ADZ28_RS21260	COG2388	GCN5-related N-acetyl-transferase
ADZ28_RS21275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADZ28_RS21280	COG3104	oligopeptide transport
ADZ28_RS21285	COG1982	Orn Lys Arg decarboxylase major
ADZ28_RS21290	COG0531	amino acid
ADZ28_RS21300	COG3710	Transcriptional regulator
ADZ28_RS21310	COG1309	transcriptional regulator
ADZ28_RS21315	COG4232	protein-disulfide reductase activity
ADZ28_RS21325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ADZ28_RS21330	COG1027	Aspartate ammonia-lyase
ADZ28_RS21335	COG3030	protein affecting phage T7 exclusion by the F plasmid
ADZ28_RS21340	COG0531	amino acid
ADZ28_RS21365	COG1509	lysine 2,3-aminomutase activity
ADZ28_RS21375	COG5510	response to toxic substance
ADZ28_RS21380	COG5510	response to toxic substance
ADZ28_RS21385	COG2076	Multidrug Resistance protein
ADZ28_RS21390	COG3040	lipid binding
ADZ28_RS21395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ADZ28_RS21410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADZ28_RS21415	COG1053	succinate dehydrogenase
ADZ28_RS21425	COG0531	amino acid
ADZ28_RS21440	COG1511	domain protein
ADZ28_RS21440	COG3264	Mechanosensitive ion channel
ADZ28_RS21475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADZ28_RS21480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADZ28_RS21480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADZ28_RS21485	COG0802	atpase or kinase
ADZ28_RS21490	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADZ28_RS21510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADZ28_RS21515	COG0330	HflC and HflK could
ADZ28_RS21520	COG0330	HflC and HflK could
ADZ28_RS21525	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ADZ28_RS21540	COG0557	exoribonuclease II activity
ADZ28_RS21545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADZ28_RS21550	COG3789	protein conserved in bacteria
ADZ28_RS21555	COG1842	Phage shock protein A
ADZ28_RS21565	COG3766	membrane
ADZ28_RS21570	COG5463	Belongs to the UPF0441 family
ADZ28_RS21575	COG0754	glutathionylspermidine amidase activity
ADZ28_RS21580	COG1960	acyl-CoA dehydrogenase activity
ADZ28_RS21590	COG3650	response to hydrogen peroxide
ADZ28_RS21595	COG1073	alpha beta
ADZ28_RS21610	COG3037	sugar-specific permease SgaT UlaA
ADZ28_RS21615	COG3414	Phosphotransferase system galactitol-specific IIB component
ADZ28_RS21620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS21660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADZ28_RS21685	COG1218	3'(2'),5'-bisphosphate nucleotidase
ADZ28_RS21695	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ADZ28_RS21705	COG1253	flavin adenine dinucleotide binding
ADZ28_RS21720	COG0729	surface antigen
ADZ28_RS21725	COG2911	Protein conserved in bacteria
ADZ28_RS21730	COG2105	PFAM AIG2 family protein
ADZ28_RS21735	COG2336	PFAM SpoVT AbrB
ADZ28_RS21740	COG2337	Toxic component of a toxin-antitoxin (TA) module
ADZ28_RS21745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ADZ28_RS21750	COG1879	ABC-type sugar transport system periplasmic component
ADZ28_RS21755	COG1129	ABC transporter
ADZ28_RS21760	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS21765	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADZ28_RS21775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADZ28_RS21785	COG0312	modulator of DNA gyrase
ADZ28_RS21790	COG3783	Cytochrome b(562)
ADZ28_RS21795	COG0602	queuosine metabolic process
ADZ28_RS21800	COG1328	CTP reductase activity
ADZ28_RS21805	COG0366	Alpha amylase catalytic
ADZ28_RS21810	COG1263	PTS System
ADZ28_RS21810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADZ28_RS21815	COG1609	Transcriptional regulator
ADZ28_RS21820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ADZ28_RS21825	COG0251	oxidation-reduction process
ADZ28_RS21850	COG0251	oxidation-reduction process
ADZ28_RS21855	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS21860	COG1309	transcriptional regulator
ADZ28_RS21865	COG2731	YhcH YjgK YiaL family protein
ADZ28_RS21875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADZ28_RS21880	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ADZ28_RS21885	COG0456	acetyltransferase
ADZ28_RS21890	COG4269	membrane
ADZ28_RS21895	COG0525	valine-tRNA ligase activity
ADZ28_RS21900	COG2927	DNA polymerase III (CHI subunit)
ADZ28_RS21910	COG0795	lipopolysaccharide-transporting ATPase activity
ADZ28_RS21915	COG0795	lipopolysaccharide-transporting ATPase activity
ADZ28_RS21920	COG0433	COG0433 Predicted ATPase
ADZ28_RS21925	COG1609	Transcriptional regulator
ADZ28_RS21930	COG2610	gluconate transmembrane transporter activity
ADZ28_RS21935	COG1028	Short-chain dehydrogenase reductase Sdr
ADZ28_RS21940	COG1063	alcohol dehydrogenase
ADZ28_RS21945	COG3265	gluconokinase activity
ADZ28_RS21950	COG1064	alcohol dehydrogenase
ADZ28_RS21960	COG0582	viral genome integration into host DNA
ADZ28_RS21995	COG3385	transposase activity
ADZ28_RS22000	COG2814	Major facilitator Superfamily
ADZ28_RS22005	COG0673	inositol 2-dehydrogenase activity
ADZ28_RS22025	COG2826	transposase and inactivated derivatives, IS30 family
ADZ28_RS22040	COG2085	NADP oxidoreductase coenzyme F420-dependent
ADZ28_RS22045	COG1120	ATPase activity
ADZ28_RS22050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADZ28_RS22055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADZ28_RS22060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ADZ28_RS22065	COG4772	TonB-dependent receptor
ADZ28_RS22070	COG3712	iron ion homeostasis
ADZ28_RS22075	COG1595	DNA-templated transcription, initiation
ADZ28_RS22095	COG2390	Transcriptional regulator
ADZ28_RS22105	COG2610	gluconate transmembrane transporter activity
ADZ28_RS22110	COG0129	dihydroxy-acid dehydratase activity
ADZ28_RS22115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADZ28_RS22120	COG1414	Transcriptional regulator
ADZ28_RS22125	COG1349	DNA-binding transcription factor activity
ADZ28_RS22130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADZ28_RS22135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADZ28_RS22140	COG0434	BtpA family
ADZ28_RS22145	COG3775	system Galactitol-specific IIC component
ADZ28_RS22150	COG3414	Phosphotransferase system galactitol-specific IIB component
ADZ28_RS22155	COG1363	Peptidase, m42
ADZ28_RS22160	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ADZ28_RS22165	COG3153	acetyltransferase
ADZ28_RS22185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADZ28_RS22185	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ADZ28_RS22195	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ADZ28_RS22200	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADZ28_RS22215	COG0582	viral genome integration into host DNA
ADZ28_RS22220	COG4974	Belongs to the 'phage' integrase family
ADZ28_RS22230	COG3539	Fimbrial protein
ADZ28_RS22235	COG3539	Fimbrial protein
ADZ28_RS22240	COG3121	Chaperone
ADZ28_RS22245	COG3188	usher protein
ADZ28_RS22250	COG3539	Fimbrial protein
ADZ28_RS22255	COG3539	Fimbrial protein
ADZ28_RS22260	COG3539	Fimbrial protein
ADZ28_RS22265	COG2610	gluconate transmembrane transporter activity
ADZ28_RS22280	COG0246	Mannitol dehydrogenase
ADZ28_RS22290	COG2186	Transcriptional regulator
ADZ28_RS22315	COG0583	DNA-binding transcription factor activity
ADZ28_RS22320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ADZ28_RS22325	COG0700	Nucleoside recognition
ADZ28_RS22330	COG3366	ferrous iron transmembrane transporter activity
ADZ28_RS22340	COG0477	Major facilitator Superfamily
ADZ28_RS22345	COG3204	pilus organization
ADZ28_RS22355	COG1924	4 iron, 4 sulfur cluster binding
ADZ28_RS22360	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ADZ28_RS22365	COG2733	membrane
ADZ28_RS22370	COG2814	Major facilitator Superfamily
ADZ28_RS22380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADZ28_RS22385	COG5457	Domain of unknown function (DUF1127)
ADZ28_RS22390	COG1196	nuclear chromosome segregation
ADZ28_RS22400	COG4268	DNA restriction-modification system
ADZ28_RS22405	COG1401	restriction endodeoxyribonuclease activity
ADZ28_RS22415	COG0732	type I restriction modification DNA specificity domain
ADZ28_RS22420	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ADZ28_RS22430	COG1715	Restriction endonuclease
ADZ28_RS22435	COG0523	cobalamin synthesis protein
ADZ28_RS22440	COG2879	small protein
ADZ28_RS22445	COG1966	Carbon starvation protein
ADZ28_RS22455	COG0840	transmembrane signaling receptor activity
ADZ28_RS22460	COG2271	Major facilitator Superfamily
ADZ28_RS22465	COG1802	Transcriptional regulator
ADZ28_RS22470	COG1063	alcohol dehydrogenase
ADZ28_RS22485	COG1484	DNA-dependent DNA replication
ADZ28_RS22500	COG2966	Psort location CytoplasmicMembrane, score
ADZ28_RS22505	COG2197	response regulator
ADZ28_RS22510	COG2197	response regulator
ADZ28_RS22515	COG4114	ferric iron reductase
ADZ28_RS22545	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ADZ28_RS22550	COG0456	acetyltransferase
ADZ28_RS22555	COG1011	Hydrolase
ADZ28_RS22565	COG2823	Periplasmic or secreted lipoprotein
ADZ28_RS22575	COG4667	esterase of the alpha-beta hydrolase superfamily
ADZ28_RS22580	COG0084	hydrolase, TatD family'
ADZ28_RS22585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ADZ28_RS22590	COG1328	CTP reductase activity
ADZ28_RS22620	COG3550	peptidyl-serine autophosphorylation
ADZ28_RS22630	COG3726	membrane protein affecting hemolysin expression
ADZ28_RS22635	COG0560	Phosphoserine phosphatase
ADZ28_RS22640	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ADZ28_RS22645	COG3172	ATPase kinase involved in NAD metabolism
ADZ28_RS22645	COG1056	cytidyltransferase-related domain
ADZ28_RS22655	COG0488	(ABC) transporter
ADZ28_RS22660	COG0741	lytic transglycosylase activity
ADZ28_RS22680	COG2207	Transcriptional regulator
ADZ28_RS22680	COG3708	Transcriptional regulator
ADZ28_RS22685	COG3045	CreA protein
ADZ28_RS22690	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS22695	COG2205	protein histidine kinase activity
ADZ28_RS22700	COG4452	Inner membrane protein CreD
ADZ28_RS22705	COG0745	RESPONSE REGULATOR receiver
ADZ28_RS22715	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA