locus-tag	class	description
EC12536_RS00020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EC12536_RS00050	COG2091	lysine biosynthetic process via aminoadipic acid
EC12536_RS00055	COG0431	NADPH-dependent FMN reductase
EC12536_RS00060	COG2252	PERMEase
EC12536_RS00070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC12536_RS00075	COG0363	glucosamine-6-phosphate deaminase activity
EC12536_RS00080	COG2382	esterase
EC12536_RS00095	COG0704	Plays a role in the regulation of phosphate uptake
EC12536_RS00100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EC12536_RS00105	COG0581	inorganic phosphate transmembrane transporter activity
EC12536_RS00110	COG0573	inorganic phosphate transmembrane transporter activity
EC12536_RS00115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EC12536_RS00120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EC12536_RS00175	COG3312	ion transport
EC12536_RS00190	COG0716	FMN binding
EC12536_RS00195	COG1522	sequence-specific DNA binding
EC12536_RS00225	COG1129	ABC transporter
EC12536_RS00230	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS00240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS00245	COG1609	Transcriptional regulator
EC12536_RS00250	COG0477	Major facilitator Superfamily
EC12536_RS00255	COG2186	Transcriptional regulator
EC12536_RS00280	COG1763	Mo-molybdopterin cofactor biosynthetic process
EC12536_RS00290	COG3084	Protein conserved in bacteria
EC12536_RS00295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EC12536_RS00305	COG0204	Acyl-transferase
EC12536_RS00335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC12536_RS00345	COG3852	Histidine kinase
EC12536_RS00360	COG1011	Hydrolase
EC12536_RS00375	COG0456	acetyltransferase
EC12536_RS00385	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EC12536_RS00400	COG2864	formate dehydrogenase
EC12536_RS00405	COG0437	4 iron, 4 sulfur cluster binding
EC12536_RS00425	COG0205	6-phosphofructokinase activity
EC12536_RS00485	COG2211	Major facilitator Superfamily
EC12536_RS00495	COG1454	alcohol dehydrogenase
EC12536_RS00500	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS00505	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS00510	COG1129	ABC transporter
EC12536_RS00555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EC12536_RS00560	COG2258	MOSC domain
EC12536_RS00565	COG2205	protein histidine kinase activity
EC12536_RS00570	COG0745	RESPONSE REGULATOR receiver
EC12536_RS00575	COG3678	ATP-independent chaperone mediated protein folding
EC12536_RS00595	COG1575	Belongs to the MenA family. Type 1 subfamily
EC12536_RS00610	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EC12536_RS00615	COG1609	Transcriptional regulator
EC12536_RS00620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EC12536_RS00635	COG0626	cystathionine gamma-synthase activity
EC12536_RS00640	COG0460	homoserine dehydrogenase
EC12536_RS00640	COG0527	aspartate kinase activity
EC12536_RS00650	COG0737	Belongs to the 5'-nucleotidase family
EC12536_RS00660	COG0583	DNA-binding transcription factor activity
EC12536_RS00670	COG0697	spore germination
EC12536_RS00675	COG0371	Dehydrogenase
EC12536_RS00685	COG2207	Transcriptional regulator
EC12536_RS00690	COG3443	Belongs to the bacterial solute-binding protein 9 family
EC12536_RS00705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EC12536_RS00730	COG0583	DNA-binding transcription factor activity
EC12536_RS00805	COG3085	chromosome segregation
EC12536_RS00825	COG3978	acetolactate synthase activity
EC12536_RS00840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC12536_RS00845	COG0583	DNA-binding transcription factor activity
EC12536_RS00855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC12536_RS00860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC12536_RS00870	COG1811	Na channel or pump
EC12536_RS00900	COG3118	belongs to the thioredoxin family
EC12536_RS00910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EC12536_RS00915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC12536_RS00925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EC12536_RS00930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC12536_RS00935	COG1088	dTDP-glucose 4,6-dehydratase activity
EC12536_RS00940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC12536_RS00945	COG0456	acetyltransferase
EC12536_RS00950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC12536_RS00955	COG2244	polysaccharide biosynthetic process
EC12536_RS01000	COG3071	HemY protein
EC12536_RS01005	COG2959	enzyme of heme biosynthesis
EC12536_RS01020	COG3072	Adenylate cyclase
EC12536_RS01050	COG1011	Hydrolase
EC12536_RS01055	COG0210	DNA helicase
EC12536_RS01090	COG1280	lysine exporter protein (LysE YggA)
EC12536_RS01100	COG1280	lysine exporter protein (LysE YggA)
EC12536_RS01105	COG2267	carboxylic ester hydrolase activity
EC12536_RS01110	COG0561	phosphatase activity
EC12536_RS01115	COG0697	spore germination
EC12536_RS01120	COG0583	DNA-binding transcription factor activity
EC12536_RS01140	COG2188	Transcriptional regulator
EC12536_RS01145	COG2149	membrane
EC12536_RS01155	COG0641	radical SAM
EC12536_RS01190	COG3051	citrate lyase alpha subunit
EC12536_RS01195	COG2301	Belongs to the HpcH HpaI aldolase family
EC12536_RS01205	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EC12536_RS01215	COG1049	propionate catabolic process, 2-methylcitrate cycle
EC12536_RS01220	COG0473	3-isopropylmalate dehydrogenase activity
EC12536_RS01225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC12536_RS01235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EC12536_RS01250	COG0583	DNA-binding transcription factor activity
EC12536_RS01280	COG3165	ubiquinone biosynthetic process from chorismate
EC12536_RS01300	COG0805	protein transport
EC12536_RS01345	COG1739	Uncharacterized protein family UPF0029
EC12536_RS01355	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EC12536_RS01435	COG0250	Participates in transcription elongation, termination and antitermination
EC12536_RS01470	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EC12536_RS01475	COG1447	Phosphotransferase system cellobiose-specific component IIA
EC12536_RS01485	COG3706	GGDEF domain
EC12536_RS01500	COG2104	thiamine diphosphate biosynthetic process
EC12536_RS01505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EC12536_RS01520	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EC12536_RS01555	COG3678	ATP-independent chaperone mediated protein folding
EC12536_RS01560	COG4191	Histidine kinase
EC12536_RS01570	COG0151	Belongs to the GarS family
EC12536_RS01600	COG0456	acetyltransferase
EC12536_RS01610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EC12536_RS01640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC12536_RS01695	COG0527	aspartate kinase activity
EC12536_RS01715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EC12536_RS01725	COG0251	oxidation-reduction process
EC12536_RS01800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EC12536_RS01810	COG0534	Mate efflux family protein
EC12536_RS01815	COG3237	CsbD-like
EC12536_RS01820	COG0735	belongs to the Fur family
EC12536_RS01830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC12536_RS01845	COG0305	Participates in initiation and elongation during chromosome replication
EC12536_RS01850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EC12536_RS01865	COG0432	Pfam Uncharacterised protein family UPF0047
EC12536_RS01870	COG2315	Protein conserved in bacteria
EC12536_RS01890	COG0741	lytic transglycosylase activity
EC12536_RS01900	COG4771	TonB-dependent receptor
EC12536_RS01920	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC12536_RS01935	COG0483	inositol monophosphate 1-phosphatase activity
EC12536_RS01940	COG1609	Transcriptional regulator
EC12536_RS01945	COG1234	tRNA 3'-trailer cleavage
EC12536_RS01980	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EC12536_RS01990	COG0789	Transcriptional regulator
EC12536_RS01995	COG0625	glutathione transferase activity
EC12536_RS02000	COG2252	PERMEase
EC12536_RS02005	COG0025	NhaP-type Na H and K H
EC12536_RS02010	COG0583	DNA-binding transcription factor activity
EC12536_RS02015	COG1380	Effector of murein hydrolase LrgA
EC12536_RS02020	COG1346	cytolysis
EC12536_RS02025	COG3539	Fimbrial protein
EC12536_RS02055	COG3162	membrane
EC12536_RS02065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EC12536_RS02075	COG1301	dicarboxylic acid transport
EC12536_RS02080	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EC12536_RS02115	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS02120	COG1129	ABC transporter
EC12536_RS02125	COG0784	Response regulator, receiver
EC12536_RS02125	COG4191	Histidine kinase
EC12536_RS02135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EC12536_RS02145	COG3454	Phosphonate metabolism
EC12536_RS02150	COG4778	phosphonate C-P lyase system protein PhnL
EC12536_RS02155	COG4107	phosphonate C-P lyase system protein PhnK
EC12536_RS02160	COG3627	carbon phosphorus lyase activity
EC12536_RS02165	COG3626	phosphonate metabolism
EC12536_RS02170	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EC12536_RS02175	COG3624	Phosphonate C-P lyase system protein PhnG
EC12536_RS02180	COG2188	Transcriptional regulator
EC12536_RS02185	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EC12536_RS02190	COG2824	Alkylphosphonate utilization operon protein PhnA
EC12536_RS02205	COG2169	Transcriptional regulator
EC12536_RS02215	COG1486	melibiose metabolic process
EC12536_RS02245	COG0861	Integral membrane protein TerC family
EC12536_RS02265	COG1215	transferase activity, transferring glycosyl groups
EC12536_RS02270	COG0726	polysaccharide deacetylase
EC12536_RS02270	COG1649	PFAM Uncharacterised BCR, COG1649
EC12536_RS02275	COG0457	Tetratricopeptide repeat
EC12536_RS02325	COG1309	transcriptional regulator
EC12536_RS02340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EC12536_RS02345	COG1027	Aspartate ammonia-lyase
EC12536_RS02355	COG3030	protein affecting phage T7 exclusion by the F plasmid
EC12536_RS02360	COG0531	amino acid
EC12536_RS02430	COG1509	lysine 2,3-aminomutase activity
EC12536_RS02445	COG5510	response to toxic substance
EC12536_RS02450	COG2076	Multidrug Resistance protein
EC12536_RS02470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC12536_RS02475	COG1053	succinate dehydrogenase
EC12536_RS02490	COG3264	Mechanosensitive ion channel
EC12536_RS02490	COG1511	domain protein
EC12536_RS02515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS02540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC12536_RS02545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EC12536_RS02545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EC12536_RS02550	COG0802	atpase or kinase
EC12536_RS02555	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC12536_RS02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EC12536_RS02580	COG0330	HflC and HflK could
EC12536_RS02585	COG0330	HflC and HflK could
EC12536_RS02600	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EC12536_RS02615	COG0557	exoribonuclease II activity
EC12536_RS02620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC12536_RS02625	COG1960	acyl-CoA dehydrogenase activity
EC12536_RS02635	COG3650	response to hydrogen peroxide
EC12536_RS02640	COG1073	alpha beta
EC12536_RS02700	COG2965	DNA replication, synthesis of RNA primer
EC12536_RS02705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EC12536_RS02715	COG3061	Opacity-associated protein A
EC12536_RS02720	COG0545	Peptidyl-prolyl cis-trans isomerase
EC12536_RS02725	COG1113	amino acid transport
EC12536_RS02735	COG0697	spore germination
EC12536_RS02745	COG0702	epimerase
EC12536_RS02750	COG1733	regulation of RNA biosynthetic process
EC12536_RS02765	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EC12536_RS02790	COG1253	flavin adenine dinucleotide binding
EC12536_RS02800	COG0729	surface antigen
EC12536_RS02805	COG2911	Protein conserved in bacteria
EC12536_RS02810	COG2105	PFAM AIG2 family protein
EC12536_RS02825	COG1879	ABC-type sugar transport system periplasmic component
EC12536_RS02830	COG1129	ABC transporter
EC12536_RS02835	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS02840	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS02850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EC12536_RS02870	COG0312	modulator of DNA gyrase
EC12536_RS02905	COG3964	amidohydrolase
EC12536_RS02920	COG2706	6-phosphogluconolactonase activity
EC12536_RS02925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS02925	COG3711	transcriptional antiterminator
EC12536_RS02930	COG3077	Addiction module antitoxin, RelB DinJ family
EC12536_RS02935	COG2026	Addiction module toxin, RelE StbE family
EC12536_RS02940	COG0602	queuosine metabolic process
EC12536_RS02960	COG1486	melibiose metabolic process
EC12536_RS02965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS02970	COG0366	Alpha amylase catalytic
EC12536_RS02975	COG1263	PTS System
EC12536_RS02975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS03020	COG2731	YhcH YjgK YiaL family protein
EC12536_RS03025	COG2222	sugar isomerase
EC12536_RS03030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS03035	COG1228	amidohydrolase
EC12536_RS03040	COG1288	antiporter activity
EC12536_RS03045	COG2188	Transcriptional regulator
EC12536_RS03070	COG0525	valine-tRNA ligase activity
EC12536_RS03075	COG2927	DNA polymerase III (CHI subunit)
EC12536_RS03090	COG0795	lipopolysaccharide-transporting ATPase activity
EC12536_RS03095	COG0795	lipopolysaccharide-transporting ATPase activity
EC12536_RS03100	COG0433	COG0433 Predicted ATPase
EC12536_RS03115	COG3718	enzyme involved in inositol metabolism
EC12536_RS03135	COG1737	Transcriptional regulator
EC12536_RS03135	COG0837	glucose binding
EC12536_RS03140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS03145	COG3962	Belongs to the TPP enzyme family
EC12536_RS03155	COG1082	Xylose isomerase domain protein TIM barrel
EC12536_RS03170	COG3842	ATPase activity
EC12536_RS03175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC12536_RS03180	COG0395	ABC-type sugar transport system, permease component
EC12536_RS03185	COG1175	transmembrane transport
EC12536_RS03190	COG1064	alcohol dehydrogenase
EC12536_RS03195	COG0659	secondary active sulfate transmembrane transporter activity
EC12536_RS03200	COG0288	reversible hydration of carbon dioxide
EC12536_RS03260	COG3507	Belongs to the glycosyl hydrolase 43 family
EC12536_RS03265	COG2211	Major facilitator Superfamily
EC12536_RS03270	COG2115	Belongs to the xylose isomerase family
EC12536_RS03275	COG4580	involved in the transport of maltose and maltodextrins
EC12536_RS03285	COG3272	Protein of unknown function (DUF1722)
EC12536_RS03305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EC12536_RS03320	COG0300	oxidoreductase activity
EC12536_RS03325	COG3631	Ketosteroid isomerase-related protein
EC12536_RS03330	COG0789	Transcriptional regulator
EC12536_RS03335	COG3040	lipid binding
EC12536_RS03345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC12536_RS03350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS03355	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS03360	COG1538	Outer membrane efflux protein
EC12536_RS03365	COG0745	RESPONSE REGULATOR receiver
EC12536_RS03370	COG5002	protein histidine kinase activity
EC12536_RS03385	COG2850	peptidyl-arginine hydroxylation
EC12536_RS03415	COG0842	Transport permease protein
EC12536_RS03420	COG0842	Transport permease protein
EC12536_RS03420	COG1129	ABC transporter
EC12536_RS03425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS03435	COG1879	ABC-type sugar transport system periplasmic component
EC12536_RS03440	COG1129	ABC transporter
EC12536_RS03445	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS03455	COG2249	NAD(P)H dehydrogenase (quinone) activity
EC12536_RS03460	COG0583	DNA-binding transcription factor activity
EC12536_RS03475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC12536_RS03480	COG5457	Domain of unknown function (DUF1127)
EC12536_RS03490	COG1566	PFAM secretion protein HlyD family protein
EC12536_RS03505	COG1924	4 iron, 4 sulfur cluster binding
EC12536_RS03510	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EC12536_RS03525	COG2733	membrane
EC12536_RS03535	COG1917	Cupin 2, conserved barrel domain protein
EC12536_RS03535	COG2207	Transcriptional regulator
EC12536_RS03540	COG5464	transposase or invertase
EC12536_RS03545	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS03555	COG0523	cobalamin synthesis protein
EC12536_RS03560	COG2879	small protein
EC12536_RS03565	COG1966	Carbon starvation protein
EC12536_RS03580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC12536_RS03585	COG2368	4-hydroxyphenylacetate
EC12536_RS03605	COG3971	2-oxopent-4-enoate hydratase activity
EC12536_RS03615	COG3384	dioxygenase
EC12536_RS03620	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS03630	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC12536_RS03635	COG1846	Transcriptional regulator
EC12536_RS03665	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EC12536_RS03680	COG3734	2-keto-3-deoxy-galactonokinase
EC12536_RS03685	COG0800	Aldolase
EC12536_RS03690	COG1737	Transcriptional regulator
EC12536_RS03700	COG0456	acetyltransferase
EC12536_RS03700	COG1214	PFAM Peptidase M22, glycoprotease
EC12536_RS03705	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EC12536_RS03705	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EC12536_RS03720	COG3715	PTS system
EC12536_RS03725	COG3716	PTS system mannose fructose sorbose family IID component
EC12536_RS03730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EC12536_RS03740	COG5464	transposase or invertase
EC12536_RS03755	COG1484	DNA-dependent DNA replication
EC12536_RS03770	COG2966	Psort location CytoplasmicMembrane, score
EC12536_RS03790	COG2197	response regulator
EC12536_RS03795	COG2197	response regulator
EC12536_RS03800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EC12536_RS03805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS03805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS03810	COG4114	ferric iron reductase
EC12536_RS03815	COG3706	GGDEF domain
EC12536_RS03845	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EC12536_RS03850	COG0456	acetyltransferase
EC12536_RS03855	COG1011	Hydrolase
EC12536_RS03865	COG2823	Periplasmic or secreted lipoprotein
EC12536_RS03875	COG4667	esterase of the alpha-beta hydrolase superfamily
EC12536_RS03880	COG0084	hydrolase, TatD family'
EC12536_RS03885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EC12536_RS03915	COG3726	membrane protein affecting hemolysin expression
EC12536_RS03925	COG0560	Phosphoserine phosphatase
EC12536_RS03930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EC12536_RS03940	COG0488	(ABC) transporter
EC12536_RS03945	COG0741	lytic transglycosylase activity
EC12536_RS03965	COG3708	Transcriptional regulator
EC12536_RS03965	COG2207	Transcriptional regulator
EC12536_RS03970	COG3045	CreA protein
EC12536_RS03975	COG0745	RESPONSE REGULATOR receiver
EC12536_RS03980	COG2205	protein histidine kinase activity
EC12536_RS03985	COG4452	Inner membrane protein CreD
EC12536_RS03990	COG0745	RESPONSE REGULATOR receiver
EC12536_RS04000	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EC12536_RS04010	COG0460	homoserine dehydrogenase
EC12536_RS04010	COG0527	aspartate kinase activity
EC12536_RS04020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EC12536_RS04035	COG1115	amino acid carrier protein
EC12536_RS04040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC12536_RS04045	COG0521	Mo-molybdopterin cofactor biosynthetic process
EC12536_RS04050	COG0477	Major facilitator Superfamily
EC12536_RS04055	COG1584	GPR1 FUN34 yaaH family protein
EC12536_RS04060	COG4735	regulation of single-species biofilm formation
EC12536_RS04085	COG0583	DNA-binding transcription factor activity
EC12536_RS04100	COG0196	riboflavin kinase activity
EC12536_RS04115	COG1047	Peptidyl-prolyl cis-trans
EC12536_RS04140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EC12536_RS04205	COG0505	Belongs to the CarA family
EC12536_RS04255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC12536_RS04265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EC12536_RS04270	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EC12536_RS04285	COG3493	citrate carrier protein
EC12536_RS04300	COG0564	pseudouridine synthase activity
EC12536_RS04310	COG0417	DNA replication proofreading
EC12536_RS04315	COG0235	Class ii aldolase
EC12536_RS04335	COG0586	Pfam SNARE associated Golgi protein
EC12536_RS04345	COG1178	ABC-type Fe3 transport system permease component
EC12536_RS04365	COG2814	Major facilitator Superfamily
EC12536_RS04370	COG2271	Major facilitator Superfamily
EC12536_RS04375	COG0583	DNA-binding transcription factor activity
EC12536_RS04385	COG0738	Major facilitator superfamily
EC12536_RS04435	COG0028	Belongs to the TPP enzyme family
EC12536_RS04445	COG1609	Transcriptional regulator
EC12536_RS04465	COG0768	penicillin binding
EC12536_RS04470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EC12536_RS04475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EC12536_RS04490	COG0772	Belongs to the SEDS family
EC12536_RS04515	COG0849	cell division
EC12536_RS04520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EC12536_RS04540	COG0494	nUDIX hydrolase
EC12536_RS04565	COG1459	type II secretion system
EC12536_RS04570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EC12536_RS04575	COG4969	Belongs to the N-Me-Phe pilin family
EC12536_RS04585	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC12536_RS04590	COG3725	Membrane protein required for beta-lactamase induction
EC12536_RS04595	COG3940	Belongs to the glycosyl hydrolase 43 family
EC12536_RS04600	COG2211	Major facilitator Superfamily
EC12536_RS04605	COG1113	amino acid transport
EC12536_RS04610	COG2186	Transcriptional regulator
EC12536_RS04615	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EC12536_RS04620	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC12536_RS04625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC12536_RS04640	COG3064	Membrane
EC12536_RS04685	COG2132	Multicopper oxidase
EC12536_RS04690	COG4993	Dehydrogenase
EC12536_RS04700	COG0288	reversible hydration of carbon dioxide
EC12536_RS04705	COG1131	(ABC) transporter
EC12536_RS04710	COG0842	Transport permease protein
EC12536_RS04715	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS04720	COG0726	polysaccharide deacetylase
EC12536_RS04740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EC12536_RS04745	COG0617	tRNA 3'-terminal CCA addition
EC12536_RS04765	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EC12536_RS04770	COG1643	Atp-dependent helicase
EC12536_RS04855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC12536_RS04860	COG4774	siderophore transport
EC12536_RS04865	COG1120	ATPase activity
EC12536_RS04870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC12536_RS04875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS04895	COG2860	membrane
EC12536_RS04915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC12536_RS04920	COG3835	regulator
EC12536_RS04935	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EC12536_RS04940	COG0024	Methionine aminopeptidase
EC12536_RS04965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EC12536_RS04980	COG0575	Belongs to the CDS family
EC12536_RS04985	COG0750	zinc metalloprotease
EC12536_RS04995	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EC12536_RS05025	COG0587	DNA-directed DNA polymerase activity
EC12536_RS05035	COG1982	Orn Lys Arg decarboxylase major
EC12536_RS05040	COG0346	lactoylglutathione lyase activity
EC12536_RS05050	COG4568	rho-dependent transcription termination
EC12536_RS05065	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EC12536_RS05070	COG3015	lipoprotein NlpE involved in copper resistance
EC12536_RS05075	COG0791	NLP P60 protein
EC12536_RS05085	COG1720	tRNA m6t6A37 methyltransferase activity
EC12536_RS05095	COG1464	Belongs to the NlpA lipoprotein family
EC12536_RS05100	COG2011	ABC-type metal ion transport system permease component
EC12536_RS05110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EC12536_RS05145	COG0656	L-ascorbic acid biosynthetic process
EC12536_RS05150	COG0583	DNA-binding transcription factor activity
EC12536_RS05155	COG2814	Major facilitator Superfamily
EC12536_RS05165	COG2226	methyltransferase
EC12536_RS05170	COG1388	LysM domain
EC12536_RS05170	COG0741	lytic transglycosylase activity
EC12536_RS05180	COG2226	methyltransferase
EC12536_RS05190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC12536_RS05200	COG0583	DNA-binding transcription factor activity
EC12536_RS05210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC12536_RS05215	COG1960	acyl-CoA dehydrogenase activity
EC12536_RS05225	COG0121	glutamine amidotransferase
EC12536_RS05230	COG3034	peptidoglycan biosynthetic process
EC12536_RS05250	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EC12536_RS05255	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EC12536_RS05270	COG2991	Protein conserved in bacteria
EC12536_RS05285	COG0454	-acetyltransferase
EC12536_RS05290	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC12536_RS05310	COG1802	Transcriptional regulator
EC12536_RS05315	COG1113	amino acid transport
EC12536_RS05320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EC12536_RS05325	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS05330	COG0579	oxidoreductase
EC12536_RS05350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EC12536_RS05355	COG0625	glutathione transferase activity
EC12536_RS05360	COG3775	system Galactitol-specific IIC component
EC12536_RS05365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC12536_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS05375	COG1070	Carbohydrate kinase
EC12536_RS05400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC12536_RS05405	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC12536_RS05410	COG0022	dehydrogenase e1 component
EC12536_RS05415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EC12536_RS05435	COG0745	RESPONSE REGULATOR receiver
EC12536_RS05450	COG3188	usher protein
EC12536_RS05455	COG3121	Chaperone
EC12536_RS05490	COG0582	viral genome integration into host DNA
EC12536_RS05515	COG0791	NLP P60 protein
EC12536_RS05550	COG3639	organic phosphonate transmembrane transporter activity
EC12536_RS05560	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EC12536_RS05585	COG3188	usher protein
EC12536_RS05600	COG0765	amino acid transport
EC12536_RS05605	COG4597	amino acid ABC transporter
EC12536_RS05610	COG1126	abc transporter atp-binding protein
EC12536_RS05615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS05655	COG4302	ethanolamine ammonia-lyase activity
EC12536_RS05660	COG4303	Ethanolamine ammonia lyase large subunit
EC12536_RS05670	COG0833	amino acid
EC12536_RS05675	COG2040	homocysteine
EC12536_RS05680	COG4521	taurine ABC transporter
EC12536_RS05685	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EC12536_RS05690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC12536_RS05695	COG2175	clavaminate synthase activity
EC12536_RS05705	COG0113	porphobilinogen synthase activity
EC12536_RS05710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EC12536_RS05715	COG1335	isochorismatase
EC12536_RS05720	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EC12536_RS05760	COG1785	Belongs to the alkaline phosphatase family
EC12536_RS05770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EC12536_RS05780	COG3416	Protein conserved in bacteria
EC12536_RS05785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EC12536_RS05795	COG4126	flavin adenine dinucleotide binding
EC12536_RS05810	COG1940	carbohydrate kinase activity
EC12536_RS05815	COG0419	ATPase involved in DNA repair
EC12536_RS05820	COG0420	3'-5' exonuclease activity
EC12536_RS05845	COG0366	Alpha amylase catalytic
EC12536_RS05850	COG0583	DNA-binding transcription factor activity
EC12536_RS05855	COG1335	isochorismatase
EC12536_RS05865	COG1228	amidohydrolase
EC12536_RS05875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS05890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS05895	COG0450	alkyl hydroperoxide reductase
EC12536_RS05915	COG1862	Preprotein translocase
EC12536_RS05920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC12536_RS05925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC12536_RS05945	COG4238	major outer membrane lipoprotein
EC12536_RS05955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC12536_RS05955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC12536_RS05975	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EC12536_RS05980	COG0667	Aldo Keto reductase
EC12536_RS05990	COG0142	geranyltranstransferase activity
EC12536_RS06010	COG0693	protein deglycase activity
EC12536_RS06015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EC12536_RS06025	COG2814	Major facilitator Superfamily
EC12536_RS06030	COG0673	inositol 2-dehydrogenase activity
EC12536_RS06045	COG1053	succinate dehydrogenase
EC12536_RS06055	COG1053	succinate dehydrogenase
EC12536_RS06060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC12536_RS06065	COG1414	Transcriptional regulator
EC12536_RS06080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EC12536_RS06085	COG1845	cytochrome c oxidase, subunit III
EC12536_RS06090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EC12536_RS06095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EC12536_RS06100	COG2223	nitrite transmembrane transporter activity
EC12536_RS06105	COG3056	Lipoprotein
EC12536_RS06110	COG0271	Belongs to the BolA IbaG family
EC12536_RS06140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EC12536_RS06145	COG0776	regulation of translation
EC12536_RS06150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC12536_RS06155	COG1555	photosystem II stabilization
EC12536_RS06160	COG0824	Thioesterase
EC12536_RS06170	COG4533	DNA binding
EC12536_RS06185	COG1522	sequence-specific DNA binding
EC12536_RS06190	COG1132	(ABC) transporter
EC12536_RS06195	COG1132	(ABC) transporter
EC12536_RS06200	COG0347	Belongs to the P(II) protein family
EC12536_RS06205	COG0004	ammonium transporteR
EC12536_RS06210	COG1946	Acyl-CoA thioesterase
EC12536_RS06215	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EC12536_RS06220	COG3695	enzyme binding
EC12536_RS06250	COG2364	Membrane
EC12536_RS06265	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EC12536_RS06275	COG2182	Extracellular solute-binding protein
EC12536_RS06280	COG1175	transmembrane transport
EC12536_RS06285	COG3833	ABC-type maltose transport systems, permease component
EC12536_RS06290	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EC12536_RS06295	COG1874	Beta-galactosidase
EC12536_RS06340	COG0110	maltose O-acetyltransferase activity
EC12536_RS06355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC12536_RS06360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS06365	COG1309	transcriptional regulator
EC12536_RS06370	COG1196	nuclear chromosome segregation
EC12536_RS06370	COG3264	Mechanosensitive ion channel
EC12536_RS06375	COG5464	transposase or invertase
EC12536_RS06385	COG3923	Primosomal replication protein n
EC12536_RS06390	COG2832	Protein of unknown function (DUF454)
EC12536_RS06430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS06435	COG4651	solute:proton antiporter activity
EC12536_RS06435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC12536_RS06440	COG2223	nitrite transmembrane transporter activity
EC12536_RS06450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EC12536_RS06455	COG3735	TraB family
EC12536_RS06470	COG1585	Membrane protein implicated in regulation of membrane protease activity
EC12536_RS06475	COG0330	HflC and HflK could
EC12536_RS06480	COG4619	ABC transporter
EC12536_RS06485	COG0390	transport system, permease component
EC12536_RS06495	COG3118	belongs to the thioredoxin family
EC12536_RS06500	COG0300	oxidoreductase activity
EC12536_RS06505	COG2755	lipolytic protein G-D-S-L family
EC12536_RS06510	COG4181	ATPase activity
EC12536_RS06515	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EC12536_RS06530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EC12536_RS06535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EC12536_RS06550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EC12536_RS06560	COG2501	S4 domain
EC12536_RS06580	COG0582	viral genome integration into host DNA
EC12536_RS06605	COG3561	AntA/AntB antirepressor
EC12536_RS06725	COG3539	Fimbrial protein
EC12536_RS06730	COG3121	Chaperone
EC12536_RS06735	COG3188	usher protein
EC12536_RS06750	COG1560	Kdo2-lipid A biosynthetic process
EC12536_RS06760	COG3710	Transcriptional regulator
EC12536_RS06765	COG0531	amino acid
EC12536_RS06770	COG1982	Orn Lys Arg decarboxylase major
EC12536_RS06775	COG3104	oligopeptide transport
EC12536_RS06805	COG0673	inositol 2-dehydrogenase activity
EC12536_RS06820	COG1129	ABC transporter
EC12536_RS06825	COG4211	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS06870	COG1566	PFAM secretion protein HlyD family protein
EC12536_RS06875	COG1120	ATPase activity
EC12536_RS06880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS06900	COG1473	amidohydrolase
EC12536_RS06905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS06910	COG0667	Aldo Keto reductase
EC12536_RS06960	COG0531	amino acid
EC12536_RS06970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC12536_RS06975	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS06990	COG1113	amino acid transport
EC12536_RS06995	COG2211	Major facilitator Superfamily
EC12536_RS07005	COG0673	inositol 2-dehydrogenase activity
EC12536_RS07015	COG1609	Transcriptional regulator
EC12536_RS07020	COG0668	transmembrane transport
EC12536_RS07025	COG0477	Major facilitator Superfamily
EC12536_RS07040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EC12536_RS07040	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EC12536_RS07045	COG2222	sugar isomerase
EC12536_RS07050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EC12536_RS07055	COG3716	PTS system mannose fructose sorbose family IID component
EC12536_RS07065	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS07075	COG0778	Nitroreductase
EC12536_RS07080	COG2315	Protein conserved in bacteria
EC12536_RS07125	COG3698	Phosphodiester glycosidase
EC12536_RS07135	COG4166	transmembrane transport
EC12536_RS07145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC12536_RS07150	COG4608	Belongs to the ABC transporter superfamily
EC12536_RS07165	COG0697	spore germination
EC12536_RS07180	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EC12536_RS07185	COG0765	amino acid transport
EC12536_RS07190	COG4215	(ABC) transporter
EC12536_RS07200	COG4221	oxidoreductase activity
EC12536_RS07205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EC12536_RS07220	COG0656	L-ascorbic acid biosynthetic process
EC12536_RS07235	COG4608	Belongs to the ABC transporter superfamily
EC12536_RS07240	COG0444	Belongs to the ABC transporter superfamily
EC12536_RS07245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC12536_RS07250	COG0601	transmembrane transport
EC12536_RS07255	COG0747	negative chemotaxis
EC12536_RS07280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EC12536_RS07290	COG0668	transmembrane transport
EC12536_RS07295	COG0583	DNA-binding transcription factor activity
EC12536_RS07305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EC12536_RS07315	COG3958	Transketolase
EC12536_RS07320	COG3959	Transketolase, thiamine diphosphate binding domain
EC12536_RS07325	COG2390	Transcriptional regulator
EC12536_RS07330	COG5464	transposase or invertase
EC12536_RS07335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS07340	COG1129	ABC transporter
EC12536_RS07350	COG1879	ABC-type sugar transport system periplasmic component
EC12536_RS07360	COG4771	TonB-dependent receptor
EC12536_RS07370	COG2382	esterase
EC12536_RS07375	COG3251	PFAM MbtH domain protein
EC12536_RS07380	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EC12536_RS07380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EC12536_RS07385	COG1120	ATPase activity
EC12536_RS07390	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS07395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS07405	COG4592	Periplasmic binding protein
EC12536_RS07410	COG1169	isochorismate synthase
EC12536_RS07415	COG1021	2,3-dihydroxybenzoate-AMP ligase
EC12536_RS07420	COG3433	isochorismatase activity
EC12536_RS07420	COG1535	isochorismatase
EC12536_RS07425	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS07435	COG1966	Carbon starvation protein
EC12536_RS07440	COG2879	small protein
EC12536_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS07460	COG0371	Dehydrogenase
EC12536_RS07465	COG1129	ABC transporter
EC12536_RS07470	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS07500	COG2271	Major facilitator Superfamily
EC12536_RS07505	COG0483	inositol monophosphate 1-phosphatase activity
EC12536_RS07515	COG0402	S-adenosylhomocysteine deaminase activity
EC12536_RS07525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EC12536_RS07540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC12536_RS07550	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS07555	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS07560	COG1129	ABC transporter
EC12536_RS07585	COG0436	Aminotransferase
EC12536_RS07590	COG1475	DNA binding
EC12536_RS07595	COG3969	phosphoadenosine phosphosulfate
EC12536_RS07600	COG0583	DNA-binding transcription factor activity
EC12536_RS07605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EC12536_RS07625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC12536_RS07630	COG3719	Belongs to the RNase T2 family
EC12536_RS07635	COG3069	C4-dicarboxylate transmembrane transporter activity
EC12536_RS07655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC12536_RS07670	COG0583	DNA-binding transcription factor activity
EC12536_RS07685	COG1686	Belongs to the peptidase S11 family
EC12536_RS07690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EC12536_RS07695	COG0772	Belongs to the SEDS family
EC12536_RS07700	COG0768	penicillin binding
EC12536_RS07710	COG0799	negative regulation of ribosome biogenesis
EC12536_RS07725	COG1466	dna polymerase III delta subunit
EC12536_RS07740	COG2888	peptidyl-tyrosine sulfation
EC12536_RS07755	COG1126	abc transporter atp-binding protein
EC12536_RS07760	COG0765	amino acid transport
EC12536_RS07765	COG0765	amino acid transport
EC12536_RS07790	COG1702	phosphate starvation-inducible protein PhoH
EC12536_RS07800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC12536_RS07845	COG0367	asparagine synthase
EC12536_RS07850	COG0647	UMP catabolic process
EC12536_RS07855	COG1940	carbohydrate kinase activity
EC12536_RS07855	COG1846	Transcriptional regulator
EC12536_RS07860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EC12536_RS07900	COG0735	belongs to the Fur family
EC12536_RS07915	COG0596	Alpha beta hydrolase
EC12536_RS07925	COG0033	Phosphoglucomutase
EC12536_RS07935	COG0745	RESPONSE REGULATOR receiver
EC12536_RS07940	COG2205	protein histidine kinase activity
EC12536_RS07970	COG0415	Belongs to the DNA photolyase family
EC12536_RS07985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EC12536_RS07990	COG1984	allophanate hydrolase subunit 2
EC12536_RS08025	COG2009	succinate dehydrogenase
EC12536_RS08030	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EC12536_RS08035	COG1053	succinate dehydrogenase
EC12536_RS08040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC12536_RS08045	COG0567	Dehydrogenase, E1 component
EC12536_RS08050	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC12536_RS08065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC12536_RS08075	COG1271	oxidase subunit
EC12536_RS08080	COG1294	oxidase, subunit
EC12536_RS08085	COG4890	Cyd operon protein YbgT
EC12536_RS08090	COG3790	cyd operon protein YbgE
EC12536_RS08095	COG0824	Thioesterase
EC12536_RS08100	COG0811	peptide transport
EC12536_RS08105	COG0848	biopolymer transport protein
EC12536_RS08110	COG3064	Membrane
EC12536_RS08120	COG2885	chlorophyll binding
EC12536_RS08125	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EC12536_RS08165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EC12536_RS08170	COG3201	nicotinamide mononucleotide transporter
EC12536_RS08185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC12536_RS08190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC12536_RS08190	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC12536_RS08205	COG0583	DNA-binding transcription factor activity
EC12536_RS08210	COG0471	metal ion transport
EC12536_RS08210	COG0490	domain, Protein
EC12536_RS08240	COG2017	converts alpha-aldose to the beta-anomer
EC12536_RS08250	COG1085	galactose-1-phosphate uridylyltransferase
EC12536_RS08260	COG1119	ATPase activity
EC12536_RS08265	COG3585	molybdate ion transport
EC12536_RS08265	COG2005	Transcriptional regulator
EC12536_RS08275	COG0725	ABC transporter, periplasmic molybdate-binding protein
EC12536_RS08280	COG4149	molybdate abc transporter
EC12536_RS08290	COG0561	phosphatase activity
EC12536_RS08315	COG2200	EAL domain
EC12536_RS08320	COG0789	Transcriptional regulator
EC12536_RS08350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS08355	COG0589	response to stress
EC12536_RS08365	COG4677	pectinesterase activity
EC12536_RS08405	COG1881	PFAM PEBP family protein
EC12536_RS08410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EC12536_RS08425	COG2226	methyltransferase
EC12536_RS08465	COG0642	Histidine kinase
EC12536_RS08470	COG0745	RESPONSE REGULATOR receiver
EC12536_RS08495	COG0521	Mo-molybdopterin cofactor biosynthetic process
EC12536_RS08505	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EC12536_RS08510	COG0314	molybdopterin synthase activity
EC12536_RS08515	COG0670	Belongs to the BI1 family
EC12536_RS08520	COG0392	lysyltransferase activity
EC12536_RS08525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC12536_RS08530	COG3568	Endonuclease Exonuclease Phosphatase
EC12536_RS08540	COG0842	Transport permease protein
EC12536_RS08545	COG0842	Transport permease protein
EC12536_RS08550	COG1131	(ABC) transporter
EC12536_RS08555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS08560	COG1309	transcriptional regulator
EC12536_RS08565	COG0583	DNA-binding transcription factor activity
EC12536_RS08570	COG2271	Major facilitator Superfamily
EC12536_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS08580	COG3959	Transketolase, thiamine diphosphate binding domain
EC12536_RS08585	COG3958	Transketolase
EC12536_RS08590	COG0513	Belongs to the DEAD box helicase family
EC12536_RS08595	COG1199	ATP-dependent helicase activity
EC12536_RS08600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EC12536_RS08610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EC12536_RS08620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC12536_RS08630	COG0668	transmembrane transport
EC12536_RS08635	COG1126	abc transporter atp-binding protein
EC12536_RS08640	COG0765	amino acid transport
EC12536_RS08645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS08660	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EC12536_RS08665	COG2194	sulfuric ester hydrolase activity
EC12536_RS08680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EC12536_RS08685	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS08690	COG2188	Transcriptional regulator
EC12536_RS08695	COG1376	ErfK ybiS ycfS ynhG family protein
EC12536_RS08700	COG2365	Tyrosine phosphatase family
EC12536_RS08705	COG0488	(ABC) transporter
EC12536_RS08720	COG2271	Major facilitator Superfamily
EC12536_RS08725	COG1609	Transcriptional regulator
EC12536_RS08735	COG0561	phosphatase activity
EC12536_RS08740	COG1882	Formate acetyltransferase
EC12536_RS08745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC12536_RS08750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EC12536_RS08755	COG0303	'Molybdopterin
EC12536_RS08770	COG0747	negative chemotaxis
EC12536_RS08795	COG2223	nitrite transmembrane transporter activity
EC12536_RS08805	COG2133	pyrroloquinoline quinone binding
EC12536_RS08810	COG0625	glutathione transferase activity
EC12536_RS08815	COG1686	Belongs to the peptidase S11 family
EC12536_RS08820	COG1349	DNA-binding transcription factor activity
EC12536_RS08825	COG0671	phosphoesterase, PA-phosphatase related
EC12536_RS08835	COG2814	Major facilitator Superfamily
EC12536_RS08840	COG0561	phosphatase activity
EC12536_RS08845	COG0738	Major facilitator superfamily
EC12536_RS08850	COG3226	Transcriptional regulator
EC12536_RS08875	COG0778	Nitroreductase
EC12536_RS08890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EC12536_RS08895	COG3842	ATPase activity
EC12536_RS08900	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC12536_RS08905	COG1177	transmembrane transport
EC12536_RS08920	COG0745	RESPONSE REGULATOR receiver
EC12536_RS08925	COG5002	protein histidine kinase activity
EC12536_RS08930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS08935	COG4160	amino acid transport
EC12536_RS08940	COG4215	(ABC) transporter
EC12536_RS08945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS08950	COG1126	abc transporter atp-binding protein
EC12536_RS08965	COG5001	Diguanylate cyclase
EC12536_RS08965	COG2203	Gaf domain
EC12536_RS08965	COG3706	GGDEF domain
EC12536_RS08965	COG4251	negative regulation of phosphorylation
EC12536_RS08970	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC12536_RS08975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC12536_RS08980	COG0702	epimerase
EC12536_RS08985	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EC12536_RS08990	COG0028	Belongs to the TPP enzyme family
EC12536_RS09000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC12536_RS09010	COG2431	L-lysine efflux transmembrane transporter activity
EC12536_RS09020	COG3593	DNA synthesis involved in DNA repair
EC12536_RS09025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS09035	COG1278	Cold shock
EC12536_RS09045	COG0542	response to heat
EC12536_RS09060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EC12536_RS09065	COG4988	ABC transporter
EC12536_RS09070	COG0492	ferredoxin-NADP+ reductase activity
EC12536_RS09080	COG1178	ABC-type Fe3 transport system permease component
EC12536_RS09080	COG1674	ftsk spoiiie
EC12536_RS09090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EC12536_RS09105	COG0437	4 iron, 4 sulfur cluster binding
EC12536_RS09110	COG3302	dmso reductase anchor subunit
EC12536_RS09120	COG0477	Major facilitator Superfamily
EC12536_RS09125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC12536_RS09130	COG1882	Formate acetyltransferase
EC12536_RS09135	COG2116	formate transmembrane transporter activity
EC12536_RS09140	COG1944	ATP diphosphatase activity
EC12536_RS09145	COG2323	membrane
EC12536_RS09165	COG0539	negative regulation of cytoplasmic translation
EC12536_RS09175	COG2333	competence protein COMEC
EC12536_RS09175	COG0658	competence protein
EC12536_RS09190	COG3214	Protein conserved in bacteria
EC12536_RS09205	COG3173	Aminoglycoside phosphotransferase
EC12536_RS09210	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EC12536_RS09215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EC12536_RS09225	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EC12536_RS09235	COG2989	Protein conserved in bacteria
EC12536_RS09240	COG3108	Peptidase M15
EC12536_RS09245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC12536_RS09250	COG1448	Aminotransferase
EC12536_RS09255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC12536_RS09265	COG1522	sequence-specific DNA binding
EC12536_RS09275	COG0814	amino acid
EC12536_RS09285	COG1473	amidohydrolase
EC12536_RS09295	COG0308	aminopeptidase N
EC12536_RS09305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC12536_RS09310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC12536_RS09315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC12536_RS09320	COG0431	NADPH-dependent FMN reductase
EC12536_RS09335	COG3217	Mosc domain protein beta barrel domain protein
EC12536_RS09335	COG0633	Ferredoxin
EC12536_RS09345	COG0488	(ABC) transporter
EC12536_RS09350	COG2995	paraquat-inducible protein a
EC12536_RS09355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EC12536_RS09355	COG3008	intermembrane lipid transfer
EC12536_RS09360	COG3009	Protein conserved in bacteria
EC12536_RS09365	COG3130	regulation of translation
EC12536_RS09375	COG1067	ATP-dependent peptidase activity
EC12536_RS09400	COG3070	regulator of competence-specific genes
EC12536_RS09405	COG1289	transmembrane transporter activity
EC12536_RS09410	COG3304	Inner membrane component domain
EC12536_RS09415	COG0210	DNA helicase
EC12536_RS09425	COG1832	CoA-binding protein
EC12536_RS09440	COG1881	PFAM PEBP family protein
EC12536_RS09445	COG2207	Transcriptional regulator
EC12536_RS09460	COG0670	Belongs to the BI1 family
EC12536_RS09475	COG2200	EAL domain
EC12536_RS09480	COG2200	EAL domain
EC12536_RS09490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC12536_RS09495	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS09500	COG4638	Rieske (2fe-2S)
EC12536_RS09505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EC12536_RS09510	COG0473	3-isopropylmalate dehydrogenase activity
EC12536_RS09515	COG0583	DNA-binding transcription factor activity
EC12536_RS09520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC12536_RS09525	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS09530	COG1917	Cupin 2, conserved barrel domain protein
EC12536_RS09530	COG1396	sequence-specific DNA binding
EC12536_RS09535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EC12536_RS09540	COG0174	glutamine synthetase
EC12536_RS09550	COG0531	amino acid
EC12536_RS09565	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS09590	COG3729	General stress protein
EC12536_RS09600	COG2233	PERMEase
EC12536_RS09635	COG1309	transcriptional regulator
EC12536_RS09650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC12536_RS09660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EC12536_RS09680	COG1702	phosphate starvation-inducible protein PhoH
EC12536_RS09695	COG1335	isochorismatase
EC12536_RS09705	COG0583	DNA-binding transcription factor activity
EC12536_RS09710	COG1309	transcriptional regulator
EC12536_RS09740	COG3381	protein complex oligomerization
EC12536_RS09780	COG5645	(Lipo)protein
EC12536_RS09800	COG1560	Kdo2-lipid A biosynthetic process
EC12536_RS09850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC12536_RS09870	COG2814	Major facilitator Superfamily
EC12536_RS09875	COG0583	DNA-binding transcription factor activity
EC12536_RS09880	COG1530	ribonuclease E activity
EC12536_RS09900	COG1399	metal-binding, possibly nucleic acid-binding protein
EC12536_RS09920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EC12536_RS09935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC12536_RS09940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EC12536_RS09945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EC12536_RS09955	COG0470	DNA polymerase III
EC12536_RS09960	COG0084	hydrolase, TatD family'
EC12536_RS09970	COG0537	adenosine 5'-monophosphoramidase activity
EC12536_RS09975	COG5633	Lipoprotein
EC12536_RS10000	COG1252	NADH dehydrogenase
EC12536_RS10005	COG3134	Outer membrane lipoprotein
EC12536_RS10015	COG1309	transcriptional regulator
EC12536_RS10025	COG1376	ErfK ybiS ycfS ynhG family protein
EC12536_RS10025	COG1388	LysM domain
EC12536_RS10030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EC12536_RS10035	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC12536_RS10045	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC12536_RS10055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EC12536_RS10065	COG2390	Transcriptional regulator
EC12536_RS10080	COG3395	kinase activity
EC12536_RS10095	COG0698	ribose 5-phosphate isomerase
EC12536_RS10100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC12536_RS10105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC12536_RS10110	COG0318	PFAM AMP-dependent synthetase and ligase
EC12536_RS10125	COG1177	transmembrane transport
EC12536_RS10145	COG2850	peptidyl-arginine hydroxylation
EC12536_RS10150	COG2205	protein histidine kinase activity
EC12536_RS10170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EC12536_RS10190	COG1187	pseudouridine synthase activity
EC12536_RS10195	COG0538	isocitrate dehydrogenase activity
EC12536_RS10200	COG0582	viral genome integration into host DNA
EC12536_RS10210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC12536_RS10225	COG1396	sequence-specific DNA binding
EC12536_RS10270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EC12536_RS10295	COG1403	HNH endonuclease
EC12536_RS10315	COG3772	lysozyme
EC12536_RS10350	COG1802	Transcriptional regulator
EC12536_RS10350	COG4626	Terminase
EC12536_RS10365	COG0616	signal peptide processing
EC12536_RS10455	COG3706	GGDEF domain
EC12536_RS10460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EC12536_RS10470	COG0538	isocitrate dehydrogenase activity
EC12536_RS10475	COG0640	Transcriptional regulator
EC12536_RS10495	COG3813	Protein conserved in bacteria
EC12536_RS10500	COG1063	alcohol dehydrogenase
EC12536_RS10505	COG3729	General stress protein
EC12536_RS10510	COG3685	Protein conserved in bacteria
EC12536_RS10515	COG3685	Protein conserved in bacteria
EC12536_RS10520	COG3546	catalase activity
EC12536_RS10525	COG1271	oxidase subunit
EC12536_RS10530	COG1294	oxidase, subunit
EC12536_RS10555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EC12536_RS10560	COG0583	DNA-binding transcription factor activity
EC12536_RS10565	COG3706	GGDEF domain
EC12536_RS10570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EC12536_RS10585	COG1560	Kdo2-lipid A biosynthetic process
EC12536_RS10595	COG3182	Iron-regulated membrane protein
EC12536_RS10615	COG2203	Gaf domain
EC12536_RS10615	COG2199	diguanylate cyclase activity
EC12536_RS10620	COG3042	response to heat
EC12536_RS10625	COG3189	MarR family transcriptional regulator
EC12536_RS10630	COG1683	Conserved Protein
EC12536_RS10635	COG0504	CTP synthase activity
EC12536_RS10640	COG2807	transmembrane transport
EC12536_RS10645	COG2207	Transcriptional regulator
EC12536_RS10655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EC12536_RS10660	COG0859	PFAM glycosyl transferase family 9
EC12536_RS10670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EC12536_RS10675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EC12536_RS10680	COG0583	DNA-binding transcription factor activity
EC12536_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS10705	COG0386	Belongs to the glutathione peroxidase family
EC12536_RS10720	COG2766	serine protein kinase
EC12536_RS10725	COG3713	MltA-interacting MipA family protein
EC12536_RS10730	COG0656	L-ascorbic acid biosynthetic process
EC12536_RS10750	COG3139	Protein of unknown function (DUF1315)
EC12536_RS10765	COG1335	isochorismatase
EC12536_RS10770	COG0252	asparaginase activity
EC12536_RS10775	COG0616	signal peptide processing
EC12536_RS10780	COG0778	Nitroreductase
EC12536_RS10800	COG0709	Synthesizes selenophosphate from selenide and ATP
EC12536_RS10805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC12536_RS10810	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS10810	COG3321	synthase
EC12536_RS10810	COG0604	alcohol dehydrogenase
EC12536_RS10815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EC12536_RS10820	COG0494	nUDIX hydrolase
EC12536_RS10825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EC12536_RS10830	COG2897	thiosulfate sulfurtransferase activity
EC12536_RS10835	COG4136	ATPase activity
EC12536_RS10840	COG4135	transport system, permease component
EC12536_RS10845	COG4134	Bacterial extracellular solute-binding protein
EC12536_RS10850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC12536_RS10855	COG0398	Pfam SNARE associated Golgi protein
EC12536_RS10860	COG0398	Pfam SNARE associated Golgi protein
EC12536_RS10865	COG0708	Exodeoxyribonuclease III
EC12536_RS10875	COG3138	arginine N-succinyltransferase
EC12536_RS10885	COG3724	N-succinylarginine dihydrolase activity
EC12536_RS10895	COG3678	ATP-independent chaperone mediated protein folding
EC12536_RS10900	COG0322	excinuclease ABC activity
EC12536_RS10910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC12536_RS10915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS10920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS10925	COG1447	Phosphotransferase system cellobiose-specific component IIA
EC12536_RS10930	COG2169	Transcriptional regulator
EC12536_RS10930	COG1917	Cupin 2, conserved barrel domain protein
EC12536_RS10935	COG1486	melibiose metabolic process
EC12536_RS10945	COG0753	catalase activity
EC12536_RS10955	COG1823	symporter activity
EC12536_RS10960	COG1988	membrane-bound metal-dependent
EC12536_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS10970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC12536_RS11000	COG0727	PFAM Uncharacterised protein family (UPF0153)
EC12536_RS11005	COG3047	cAMP biosynthetic process
EC12536_RS11015	COG4774	siderophore transport
EC12536_RS11070	COG0135	phosphoribosylanthranilate isomerase activity
EC12536_RS11070	COG0134	indole-3-glycerol-phosphate synthase activity
EC12536_RS11075	COG0512	Glutamine amidotransferase of anthranilate synthase
EC12536_RS11075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EC12536_RS11080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EC12536_RS11090	COG0009	L-threonylcarbamoyladenylate synthase
EC12536_RS11100	COG0583	DNA-binding transcription factor activity
EC12536_RS11130	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EC12536_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS11145	COG0616	signal peptide processing
EC12536_RS11175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EC12536_RS11185	COG0671	phosphoesterase, PA-phosphatase related
EC12536_RS11190	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EC12536_RS11195	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EC12536_RS11205	COG0023	Translation Initiation Factor
EC12536_RS11215	COG1349	DNA-binding transcription factor activity
EC12536_RS11230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC12536_RS11230	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC12536_RS11235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EC12536_RS11245	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EC12536_RS11260	COG4171	peptide transport system, permease
EC12536_RS11285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC12536_RS11340	COG1846	Transcriptional regulator
EC12536_RS11495	COG3728	DNA packaging
EC12536_RS11495	COG5484	DNA packaging
EC12536_RS11580	COG1196	nuclear chromosome segregation
EC12536_RS11580	COG1196	nuclear chromosome segregation
EC12536_RS11635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EC12536_RS11640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EC12536_RS11665	COG0702	epimerase
EC12536_RS11680	COG1473	amidohydrolase
EC12536_RS11690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EC12536_RS11695	COG1842	Phage shock protein A
EC12536_RS11705	COG1983	PspC domain protein
EC12536_RS11715	COG3106	COG3106 Predicted ATPase
EC12536_RS11725	COG0583	DNA-binding transcription factor activity
EC12536_RS11730	COG1486	melibiose metabolic process
EC12536_RS11740	COG3180	Ammonia monooxygenase
EC12536_RS11745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EC12536_RS11750	COG4948	Mandelate Racemase Muconate Lactonizing
EC12536_RS11755	COG2866	Carboxypeptidase
EC12536_RS11760	COG4166	transmembrane transport
EC12536_RS11790	COG0656	L-ascorbic acid biosynthetic process
EC12536_RS11810	COG0583	DNA-binding transcription factor activity
EC12536_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS11820	COG1078	dGTPase activity
EC12536_RS11825	COG0693	protein deglycase activity
EC12536_RS11850	COG2885	chlorophyll binding
EC12536_RS11960	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS11965	COG1309	transcriptional regulator
EC12536_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS11990	COG0583	DNA-binding transcription factor activity
EC12536_RS12015	COG0604	alcohol dehydrogenase
EC12536_RS12020	COG0436	Aminotransferase
EC12536_RS12035	COG2011	ABC-type metal ion transport system permease component
EC12536_RS12040	COG1448	Aminotransferase
EC12536_RS12050	COG1522	sequence-specific DNA binding
EC12536_RS12055	COG1113	amino acid transport
EC12536_RS12070	COG0673	inositol 2-dehydrogenase activity
EC12536_RS12075	COG1349	DNA-binding transcription factor activity
EC12536_RS12090	COG0513	Belongs to the DEAD box helicase family
EC12536_RS12100	COG0589	response to stress
EC12536_RS12110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC12536_RS12115	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC12536_RS12115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EC12536_RS12115	COG1013	pyruvate-flavodoxin oxidoreductase activity
EC12536_RS12115	COG0674	pyruvate-flavodoxin oxidoreductase activity
EC12536_RS12125	COG3042	response to heat
EC12536_RS12130	COG3187	Heat shock protein
EC12536_RS12135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC12536_RS12140	COG0586	Pfam SNARE associated Golgi protein
EC12536_RS12145	COG2911	Protein conserved in bacteria
EC12536_RS12155	COG3784	Protein of unknown function (DUF1318)
EC12536_RS12160	COG2207	Transcriptional regulator
EC12536_RS12165	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS12180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS12190	COG1126	abc transporter atp-binding protein
EC12536_RS12195	COG0583	DNA-binding transcription factor activity
EC12536_RS12200	COG2072	flavoprotein involved in K transport
EC12536_RS12245	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS12245	COG2030	dehydratase
EC12536_RS12250	COG3396	Phenylacetate-CoA oxygenase
EC12536_RS12255	COG3460	Phenylacetate-CoA oxygenase
EC12536_RS12260	COG3396	Phenylacetate-CoA oxygenase
EC12536_RS12265	COG2151	metal-sulfur cluster biosynthetic enzyme
EC12536_RS12270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC12536_RS12275	COG1024	Enoyl-CoA hydratase
EC12536_RS12280	COG1024	Enoyl-CoA hydratase
EC12536_RS12285	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC12536_RS12290	COG2050	protein possibly involved in aromatic compounds catabolism
EC12536_RS12295	COG0183	Belongs to the thiolase family
EC12536_RS12300	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EC12536_RS12305	COG3327	negative regulation of DNA-templated transcription, initiation
EC12536_RS12310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EC12536_RS12325	COG1643	Atp-dependent helicase
EC12536_RS12330	COG4122	O-methyltransferase activity
EC12536_RS12355	COG0583	DNA-binding transcription factor activity
EC12536_RS12360	COG0667	Aldo Keto reductase
EC12536_RS12365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EC12536_RS12370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC12536_RS12375	COG3138	arginine N-succinyltransferase
EC12536_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS12385	COG3724	N-succinylarginine dihydrolase activity
EC12536_RS12390	COG2988	succinylglutamate desuccinylase activity
EC12536_RS12395	COG1113	amino acid transport
EC12536_RS12405	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EC12536_RS12410	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS12415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EC12536_RS12420	COG0401	homolog of Blt101
EC12536_RS12425	COG5562	phage envelope protein
EC12536_RS12430	COG0425	Belongs to the sulfur carrier protein TusA family
EC12536_RS12435	COG2391	methyltransferase activity
EC12536_RS12460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EC12536_RS12465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS12465	COG1263	PTS System
EC12536_RS12470	COG1609	Transcriptional regulator
EC12536_RS12475	COG5339	Protein conserved in bacteria
EC12536_RS12480	COG1482	cell wall glycoprotein biosynthetic process
EC12536_RS12485	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC12536_RS12485	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC12536_RS12490	COG0114	fumarate hydratase activity
EC12536_RS12500	COG2205	protein histidine kinase activity
EC12536_RS12510	COG0745	RESPONSE REGULATOR receiver
EC12536_RS12515	COG3136	membrane protein required for alginate biosynthesis
EC12536_RS12525	COG0531	amino acid
EC12536_RS12545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EC12536_RS12550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EC12536_RS12565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC12536_RS12660	COG1061	Type III restriction enzyme res subunit
EC12536_RS12880	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EC12536_RS12885	COG1473	amidohydrolase
EC12536_RS12895	COG0583	DNA-binding transcription factor activity
EC12536_RS12900	COG2840	Smr protein MutS2
EC12536_RS12905	COG1414	Transcriptional regulator
EC12536_RS12915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC12536_RS12920	COG0183	Belongs to the thiolase family
EC12536_RS12930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EC12536_RS12935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC12536_RS12950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC12536_RS12950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC12536_RS12975	COG4565	transcriptional regulatory protein
EC12536_RS12980	COG3290	protein histidine kinase activity
EC12536_RS13020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EC12536_RS13030	COG0679	Auxin Efflux Carrier
EC12536_RS13060	COG0628	permease
EC12536_RS13080	COG3591	Belongs to the peptidase S1B family
EC12536_RS13090	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EC12536_RS13095	COG2814	Major facilitator Superfamily
EC12536_RS13100	COG0583	DNA-binding transcription factor activity
EC12536_RS13105	COG1940	carbohydrate kinase activity
EC12536_RS13110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EC12536_RS13125	COG3302	dmso reductase anchor subunit
EC12536_RS13130	COG0437	4 iron, 4 sulfur cluster binding
EC12536_RS13135	COG0243	molybdopterin cofactor binding
EC12536_RS13150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC12536_RS13165	COG2271	Major facilitator Superfamily
EC12536_RS13170	COG0246	Mannitol dehydrogenase
EC12536_RS13175	COG0589	response to stress
EC12536_RS13180	COG1802	Transcriptional regulator
EC12536_RS13185	COG4221	oxidoreductase activity
EC12536_RS13200	COG2207	Transcriptional regulator
EC12536_RS13205	COG2135	peptidase activity
EC12536_RS13225	COG0071	Belongs to the small heat shock protein (HSP20) family
EC12536_RS13230	COG1546	Belongs to the CinA family
EC12536_RS13235	COG2200	EAL domain
EC12536_RS13250	COG3708	Transcriptional regulator
EC12536_RS13250	COG2207	Transcriptional regulator
EC12536_RS13255	COG2610	gluconate transmembrane transporter activity
EC12536_RS13260	COG3622	Belongs to the hyi family
EC12536_RS13265	COG0235	Class ii aldolase
EC12536_RS13270	COG3395	kinase activity
EC12536_RS13275	COG2084	Dehydrogenase
EC12536_RS13280	COG1349	DNA-binding transcription factor activity
EC12536_RS13295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EC12536_RS13300	COG2223	nitrite transmembrane transporter activity
EC12536_RS13335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EC12536_RS13370	COG2814	Major facilitator Superfamily
EC12536_RS13375	COG0697	spore germination
EC12536_RS13385	COG4977	sequence-specific DNA binding
EC12536_RS13410	COG2271	Major facilitator Superfamily
EC12536_RS13415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC12536_RS13420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC12536_RS13430	COG3395	kinase activity
EC12536_RS13435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC12536_RS13440	COG1349	DNA-binding transcription factor activity
EC12536_RS13445	COG0039	L-malate dehydrogenase activity
EC12536_RS13455	COG0583	DNA-binding transcription factor activity
EC12536_RS13460	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS13475	COG2199	diguanylate cyclase activity
EC12536_RS13555	COG0477	Major facilitator Superfamily
EC12536_RS13565	COG2070	2-Nitropropane dioxygenase
EC12536_RS13570	COG2011	ABC-type metal ion transport system permease component
EC12536_RS13590	COG4628	conserved protein (DUF2132)
EC12536_RS13605	COG2207	Transcriptional regulator
EC12536_RS13635	COG2233	PERMEase
EC12536_RS13640	COG3648	Uricase
EC12536_RS13640	COG3195	allantoin biosynthetic process
EC12536_RS13645	COG2351	hydroxyisourate hydrolase activity
EC12536_RS13650	COG1396	sequence-specific DNA binding
EC12536_RS13655	COG3550	peptidyl-serine autophosphorylation
EC12536_RS13660	COG1649	PFAM Uncharacterised BCR, COG1649
EC12536_RS13670	COG3188	usher protein
EC12536_RS13705	COG3300	MHYT domain
EC12536_RS13705	COG5001	Diguanylate cyclase
EC12536_RS13710	COG2819	hydrolase of the alpha beta superfamily
EC12536_RS13720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS13720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS13725	COG2814	Major facilitator Superfamily
EC12536_RS13735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS13735	COG1263	PTS System
EC12536_RS13740	COG2186	Transcriptional regulator
EC12536_RS13760	COG3835	regulator
EC12536_RS13765	COG1929	Belongs to the glycerate kinase type-1 family
EC12536_RS13810	COG0738	Major facilitator superfamily
EC12536_RS13815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS13820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC12536_RS13825	COG1349	DNA-binding transcription factor activity
EC12536_RS13840	COG1349	DNA-binding transcription factor activity
EC12536_RS13845	COG4977	sequence-specific DNA binding
EC12536_RS13865	COG4977	sequence-specific DNA binding
EC12536_RS13880	COG0667	Aldo Keto reductase
EC12536_RS13885	COG3386	PFAM SMP-30 Gluconolaconase
EC12536_RS13890	COG0667	Aldo Keto reductase
EC12536_RS13895	COG0667	Aldo Keto reductase
EC12536_RS13905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EC12536_RS13905	COG0456	acetyltransferase
EC12536_RS13930	COG1652	LysM domain
EC12536_RS13960	COG1609	Transcriptional regulator
EC12536_RS13970	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS13985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EC12536_RS13995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC12536_RS14000	COG0583	DNA-binding transcription factor activity
EC12536_RS14005	COG0583	DNA-binding transcription factor activity
EC12536_RS14020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EC12536_RS14020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC12536_RS14020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC12536_RS14025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC12536_RS14035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC12536_RS14040	COG3037	sugar-specific permease SgaT UlaA
EC12536_RS14050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS14055	COG1609	Transcriptional regulator
EC12536_RS14065	COG2223	nitrite transmembrane transporter activity
EC12536_RS14095	COG0477	Major facilitator Superfamily
EC12536_RS14100	COG4529	Protein conserved in bacteria
EC12536_RS14105	COG1902	pentaerythritol trinitrate reductase activity
EC12536_RS14115	COG0583	DNA-binding transcription factor activity
EC12536_RS14120	COG2070	2-Nitropropane dioxygenase
EC12536_RS14130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EC12536_RS14140	COG0765	amino acid transport
EC12536_RS14185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC12536_RS14205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC12536_RS14225	COG2207	Transcriptional regulator
EC12536_RS14245	COG0406	alpha-ribazole phosphatase activity
EC12536_RS14280	COG1953	Uracil, thiamine, allantoin
EC12536_RS14290	COG3706	GGDEF domain
EC12536_RS14295	COG1609	Transcriptional regulator
EC12536_RS14305	COG0673	inositol 2-dehydrogenase activity
EC12536_RS14315	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EC12536_RS14320	COG1116	anion transmembrane transporter activity
EC12536_RS14325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC12536_RS14330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC12536_RS14335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EC12536_RS14340	COG0076	glutamate decarboxylase activity
EC12536_RS14355	COG2205	protein histidine kinase activity
EC12536_RS14365	COG0596	Alpha beta hydrolase
EC12536_RS14405	COG0519	Catalyzes the synthesis of GMP from XMP
EC12536_RS14405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EC12536_RS14425	COG0583	DNA-binding transcription factor activity
EC12536_RS14435	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EC12536_RS14440	COG1285	pathogenesis
EC12536_RS14450	COG2814	Major facilitator Superfamily
EC12536_RS14455	COG1447	Phosphotransferase system cellobiose-specific component IIA
EC12536_RS14460	COG0583	DNA-binding transcription factor activity
EC12536_RS14465	COG0243	molybdopterin cofactor binding
EC12536_RS14470	COG3781	membrane
EC12536_RS14495	COG1764	response to oxidative stress
EC12536_RS14500	COG3111	PFAM Bacterial OB fold (BOF) protein
EC12536_RS14510	COG2323	membrane
EC12536_RS14520	COG0366	Alpha amylase catalytic
EC12536_RS14530	COG3685	Protein conserved in bacteria
EC12536_RS14550	COG3729	General stress protein
EC12536_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS14595	COG0488	(ABC) transporter
EC12536_RS14610	COG1064	alcohol dehydrogenase
EC12536_RS14615	COG0747	negative chemotaxis
EC12536_RS14625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC12536_RS14635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC12536_RS14645	COG2814	Major facilitator Superfamily
EC12536_RS14655	COG2326	polyphosphate kinase activity
EC12536_RS14670	COG2864	formate dehydrogenase
EC12536_RS14675	COG0437	4 iron, 4 sulfur cluster binding
EC12536_RS14700	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EC12536_RS14710	COG3485	protocatechuate 3,4-dioxygenase
EC12536_RS14715	COG4829	muconolactone delta-isomerase
EC12536_RS14720	COG4948	Mandelate Racemase Muconate Lactonizing
EC12536_RS14725	COG1414	Transcriptional regulator
EC12536_RS14745	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EC12536_RS14750	COG1140	nitrate reductase beta subunit
EC12536_RS14755	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EC12536_RS14760	COG2181	nitrate reductase activity
EC12536_RS14765	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EC12536_RS14770	COG1178	ABC-type Fe3 transport system permease component
EC12536_RS14775	COG1840	ABC-type Fe3 transport system, periplasmic component
EC12536_RS14780	COG3842	ATPase activity
EC12536_RS14785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EC12536_RS14800	COG0625	glutathione transferase activity
EC12536_RS14805	COG1609	Transcriptional regulator
EC12536_RS14815	COG2271	Major facilitator Superfamily
EC12536_RS14825	COG1126	abc transporter atp-binding protein
EC12536_RS14830	COG0765	amino acid transport
EC12536_RS14840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS14845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC12536_RS14850	COG1473	amidohydrolase
EC12536_RS14855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC12536_RS14860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EC12536_RS14885	COG4772	TonB-dependent receptor
EC12536_RS14890	COG1228	amidohydrolase
EC12536_RS14895	COG3691	Protein conserved in bacteria
EC12536_RS14910	COG2130	NADP-dependent
EC12536_RS14920	COG1247	-acetyltransferase
EC12536_RS14925	COG3238	Protein conserved in bacteria
EC12536_RS14935	COG0747	negative chemotaxis
EC12536_RS14940	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS14970	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS14975	COG1177	transmembrane transport
EC12536_RS14980	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC12536_RS14985	COG3842	ATPase activity
EC12536_RS14990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EC12536_RS14995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC12536_RS15000	COG1271	oxidase subunit
EC12536_RS15005	COG1294	oxidase, subunit
EC12536_RS15025	COG0826	peptidase U32
EC12536_RS15035	COG1396	sequence-specific DNA binding
EC12536_RS15040	COG3135	benzoate transporter
EC12536_RS15045	COG3708	Transcriptional regulator
EC12536_RS15045	COG2207	Transcriptional regulator
EC12536_RS15060	COG0500	methyltransferase
EC12536_RS15065	COG1275	C4-dicarboxylate transporter malic acid transport protein
EC12536_RS15070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EC12536_RS15075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC12536_RS15090	COG2272	Belongs to the type-B carboxylesterase lipase family
EC12536_RS15095	COG5383	Protein conserved in bacteria
EC12536_RS15100	COG3485	protocatechuate 3,4-dioxygenase
EC12536_RS15105	COG3485	protocatechuate 3,4-dioxygenase
EC12536_RS15110	COG0583	DNA-binding transcription factor activity
EC12536_RS15130	COG3038	cytochrome b561
EC12536_RS15150	COG2814	Major facilitator Superfamily
EC12536_RS15160	COG0673	inositol 2-dehydrogenase activity
EC12536_RS15170	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS15205	COG4659	FMN binding
EC12536_RS15215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EC12536_RS15230	COG0625	glutathione transferase activity
EC12536_RS15235	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EC12536_RS15250	COG3895	Periplasmic Protein
EC12536_RS15265	COG3706	GGDEF domain
EC12536_RS15280	COG1566	PFAM secretion protein HlyD family protein
EC12536_RS15285	COG1289	transmembrane transporter activity
EC12536_RS15290	COG2032	superoxide dismutase activity
EC12536_RS15295	COG4989	oxidoreductase activity
EC12536_RS15300	COG3313	Fe-S protein
EC12536_RS15305	COG1309	transcriptional regulator
EC12536_RS15310	COG1902	pentaerythritol trinitrate reductase activity
EC12536_RS15315	COG0346	lactoylglutathione lyase activity
EC12536_RS15325	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EC12536_RS15330	COG0791	NLP P60 protein
EC12536_RS15345	COG2814	Major facilitator Superfamily
EC12536_RS15360	COG0583	DNA-binding transcription factor activity
EC12536_RS15365	COG2814	Major facilitator Superfamily
EC12536_RS15370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EC12536_RS15375	COG0307	riboflavin synthase, alpha
EC12536_RS15430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EC12536_RS15460	COG1349	DNA-binding transcription factor activity
EC12536_RS15465	COG0346	lactoylglutathione lyase activity
EC12536_RS15490	COG0444	Belongs to the ABC transporter superfamily
EC12536_RS15495	COG4608	Belongs to the ABC transporter superfamily
EC12536_RS15525	COG0604	alcohol dehydrogenase
EC12536_RS15525	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS15525	COG3321	synthase
EC12536_RS15570	COG0402	S-adenosylhomocysteine deaminase activity
EC12536_RS15595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC12536_RS15600	COG0277	FAD linked oxidase domain protein
EC12536_RS15625	COG0583	DNA-binding transcription factor activity
EC12536_RS15635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EC12536_RS15645	COG1250	3-hydroxyacyl-CoA dehydrogenase
EC12536_RS15650	COG2610	gluconate transmembrane transporter activity
EC12536_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS15690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC12536_RS15710	COG0745	RESPONSE REGULATOR receiver
EC12536_RS15715	COG3850	Histidine kinase
EC12536_RS15715	COG5002	protein histidine kinase activity
EC12536_RS15735	COG3088	subunit of a heme lyase
EC12536_RS15735	COG4235	cytochrome complex assembly
EC12536_RS15740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC12536_RS15745	COG1138	Cytochrome C-type biogenesis protein
EC12536_RS15760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC12536_RS15765	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC12536_RS15770	COG4133	protoheme IX ABC transporter activity
EC12536_RS15800	COG3157	Type VI secretion system effector, Hcp
EC12536_RS15805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC12536_RS15810	COG1518	maintenance of DNA repeat elements
EC12536_RS15820	COG1857	crispr-associated protein
EC12536_RS15855	COG1175	transmembrane transport
EC12536_RS15870	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EC12536_RS15875	COG3383	formate dehydrogenase (NAD+) activity
EC12536_RS15880	COG1473	amidohydrolase
EC12536_RS15910	COG1126	abc transporter atp-binding protein
EC12536_RS15915	COG0765	amino acid transport
EC12536_RS15935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS15940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS15945	COG1120	ATPase activity
EC12536_RS15950	COG4774	siderophore transport
EC12536_RS15955	COG1116	anion transmembrane transporter activity
EC12536_RS15960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EC12536_RS15980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC12536_RS15985	COG0583	DNA-binding transcription factor activity
EC12536_RS16005	COG2814	Major facilitator Superfamily
EC12536_RS16040	COG1414	Transcriptional regulator
EC12536_RS16045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC12536_RS16050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS16055	COG1120	ATPase activity
EC12536_RS16065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC12536_RS16070	COG2271	Major facilitator Superfamily
EC12536_RS16075	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EC12536_RS16075	COG1082	Xylose isomerase domain protein TIM barrel
EC12536_RS16080	COG1309	transcriptional regulator
EC12536_RS16105	COG1376	ErfK ybiS ycfS ynhG family protein
EC12536_RS16120	COG0719	Fe-S assembly protein
EC12536_RS16125	COG0396	ATPase activity
EC12536_RS16130	COG0719	Fe-S assembly protein
EC12536_RS16135	COG0316	Belongs to the HesB IscA family
EC12536_RS16150	COG1304	FMN binding
EC12536_RS16175	COG0583	DNA-binding transcription factor activity
EC12536_RS16185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS16190	COG1120	ATPase activity
EC12536_RS16220	COG2261	transglycosylase associated protein
EC12536_RS16225	COG2050	protein possibly involved in aromatic compounds catabolism
EC12536_RS16230	COG0247	lactate metabolic process
EC12536_RS16230	COG0277	FAD linked oxidase domain protein
EC12536_RS16235	COG0628	permease
EC12536_RS16245	COG0574	Belongs to the PEP-utilizing enzyme family
EC12536_RS16245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC12536_RS16255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC12536_RS16260	COG4256	Hemin uptake protein
EC12536_RS16270	COG0791	NLP P60 protein
EC12536_RS16280	COG0386	Belongs to the glutathione peroxidase family
EC12536_RS16300	COG0583	DNA-binding transcription factor activity
EC12536_RS16320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC12536_RS16320	COG0072	phenylalanine-tRNA ligase activity
EC12536_RS16365	COG3137	Salt-induced outer membrane protein
EC12536_RS16370	COG1105	Belongs to the carbohydrate kinase PfkB family
EC12536_RS16380	COG3001	Fructosamine kinase
EC12536_RS16390	COG2350	Protein conserved in bacteria
EC12536_RS16395	COG2353	YceI-like domain
EC12536_RS16415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC12536_RS16425	COG0444	Belongs to the ABC transporter superfamily
EC12536_RS16430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC12536_RS16435	COG0601	transmembrane transport
EC12536_RS16440	COG4166	transmembrane transport
EC12536_RS16445	COG2095	MarC family integral membrane protein
EC12536_RS16455	COG1454	alcohol dehydrogenase
EC12536_RS16455	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS16460	COG1435	thymidine kinase activity
EC12536_RS16465	COG2916	Histone family protein nucleoid-structuring protein H-NS
EC12536_RS16470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EC12536_RS16475	COG0745	RESPONSE REGULATOR receiver
EC12536_RS16480	COG1752	Esterase of the alpha-beta hydrolase superfamily
EC12536_RS16490	COG0788	formyltetrahydrofolate deformylase activity
EC12536_RS16525	COG1522	sequence-specific DNA binding
EC12536_RS16535	COG2181	nitrate reductase activity
EC12536_RS16540	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EC12536_RS16545	COG1140	nitrate reductase beta subunit
EC12536_RS16550	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EC12536_RS16555	COG2223	nitrite transmembrane transporter activity
EC12536_RS16560	COG3850	Histidine kinase
EC12536_RS16565	COG2197	response regulator
EC12536_RS16570	COG4932	domain protein
EC12536_RS16575	COG0243	molybdopterin cofactor binding
EC12536_RS16580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EC12536_RS16580	COG2146	nitrite reductase [NAD(P)H] activity
EC12536_RS16585	COG1116	anion transmembrane transporter activity
EC12536_RS16595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC12536_RS16600	COG3707	response regulator
EC12536_RS16605	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EC12536_RS16615	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EC12536_RS16620	COG4572	Cation transport regulator
EC12536_RS16625	COG0387	Pfam Sodium calcium exchanger
EC12536_RS16645	COG2890	protein-(glutamine-N5) methyltransferase activity
EC12536_RS16675	COG0659	secondary active sulfate transmembrane transporter activity
EC12536_RS16695	COG0012	GTP binding
EC12536_RS16760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EC12536_RS16830	COG2885	chlorophyll binding
EC12536_RS16855	COG3122	Protein conserved in bacteria
EC12536_RS16870	COG0583	DNA-binding transcription factor activity
EC12536_RS16900	COG0583	DNA-binding transcription factor activity
EC12536_RS16930	COG1882	Formate acetyltransferase
EC12536_RS16945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EC12536_RS16950	COG0583	DNA-binding transcription factor activity
EC12536_RS16995	COG2308	Evidence 4 Homologs of previously reported genes of
EC12536_RS17010	COG4774	siderophore transport
EC12536_RS17020	COG1619	proteins homologs of microcin C7 resistance protein MccF
EC12536_RS17040	COG2719	SpoVR family
EC12536_RS17070	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC12536_RS17085	COG2894	cell division
EC12536_RS17095	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EC12536_RS17105	COG3065	identical protein binding
EC12536_RS17115	COG1199	ATP-dependent helicase activity
EC12536_RS17120	COG0251	oxidation-reduction process
EC12536_RS17140	COG1760	l-serine dehydratase
EC12536_RS17145	COG2200	EAL domain
EC12536_RS17150	COG1253	flavin adenine dinucleotide binding
EC12536_RS17155	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS17155	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS17160	COG3715	PTS system
EC12536_RS17165	COG3716	PTS system mannose fructose sorbose family IID component
EC12536_RS17180	COG2226	methyltransferase
EC12536_RS17185	COG0768	penicillin binding
EC12536_RS17225	COG1414	Transcriptional regulator
EC12536_RS17235	COG2814	Major facilitator Superfamily
EC12536_RS17255	COG1956	GAF domain-containing protein
EC12536_RS17260	COG2995	paraquat-inducible protein a
EC12536_RS17265	COG3008	intermembrane lipid transfer
EC12536_RS17290	COG2990	Protein conserved in bacteria
EC12536_RS17305	COG1276	copper resistance
EC12536_RS17310	COG2372	response to copper ion
EC12536_RS17320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EC12536_RS17325	COG1770	oligopeptidase
EC12536_RS17330	COG2979	Protein of unknown function (DUF533)
EC12536_RS17335	COG3141	response to X-ray
EC12536_RS17345	COG0800	Aldolase
EC12536_RS17350	COG0129	dihydroxy-acid dehydratase activity
EC12536_RS17355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EC12536_RS17370	COG1737	Transcriptional regulator
EC12536_RS17380	COG1560	Kdo2-lipid A biosynthetic process
EC12536_RS17385	COG0739	heme binding
EC12536_RS17390	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EC12536_RS17400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC12536_RS17425	COG0494	nUDIX hydrolase
EC12536_RS17435	COG1335	isochorismatase
EC12536_RS17440	COG1801	Protein of unknown function DUF72
EC12536_RS17445	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EC12536_RS17465	COG3102	Protein conserved in bacteria
EC12536_RS17475	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EC12536_RS17500	COG1172	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS17510	COG1879	ABC-type sugar transport system periplasmic component
EC12536_RS17520	COG1528	Iron-storage protein
EC12536_RS17530	COG2211	Major facilitator Superfamily
EC12536_RS17540	COG0477	Major facilitator Superfamily
EC12536_RS17555	COG1528	Iron-storage protein
EC12536_RS17565	COG0814	amino acid
EC12536_RS17570	COG3012	SEC-C Motif Domain Protein
EC12536_RS17570	COG3318	Belongs to the UPF0149 family
EC12536_RS17605	COG2197	response regulator
EC12536_RS17615	COG2197	response regulator
EC12536_RS17620	COG1126	abc transporter atp-binding protein
EC12536_RS17625	COG0765	amino acid transport
EC12536_RS17635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS17640	COG0366	Alpha amylase catalytic
EC12536_RS17670	COG2354	Protein conserved in bacteria
EC12536_RS17675	COG0697	spore germination
EC12536_RS17680	COG3727	T/G mismatch-specific endonuclease activity
EC12536_RS17685	COG0270	DNA (cytosine-5-)-methyltransferase activity
EC12536_RS17690	COG1418	mRNA catabolic process
EC12536_RS17705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EC12536_RS17750	COG0025	NhaP-type Na H and K H
EC12536_RS17755	COG1309	transcriptional regulator
EC12536_RS17760	COG0604	alcohol dehydrogenase
EC12536_RS17780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC12536_RS17790	COG0534	Mate efflux family protein
EC12536_RS17800	COG0582	viral genome integration into host DNA
EC12536_RS17815	COG1737	Transcriptional regulator
EC12536_RS17830	COG2814	Major facilitator Superfamily
EC12536_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS17850	COG4977	sequence-specific DNA binding
EC12536_RS17855	COG1566	PFAM secretion protein HlyD family protein
EC12536_RS17870	COG2207	Transcriptional regulator
EC12536_RS17895	COG3706	GGDEF domain
EC12536_RS17920	COG3615	Tellurite resistance protein tehB
EC12536_RS17930	COG5001	Diguanylate cyclase
EC12536_RS17930	COG3300	MHYT domain
EC12536_RS17945	COG0477	Major facilitator Superfamily
EC12536_RS17950	COG0095	Lipoate-protein ligase
EC12536_RS17955	COG0583	DNA-binding transcription factor activity
EC12536_RS17960	COG1942	4-Oxalocrotonate Tautomerase
EC12536_RS17970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EC12536_RS17990	COG1289	transmembrane transporter activity
EC12536_RS18005	COG2925	Exonuclease
EC12536_RS18010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EC12536_RS18015	COG0640	Transcriptional regulator
EC12536_RS18020	COG0531	amino acid
EC12536_RS18030	COG0583	DNA-binding transcription factor activity
EC12536_RS18035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC12536_RS18065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EC12536_RS18120	COG1088	dTDP-glucose 4,6-dehydratase activity
EC12536_RS18180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EC12536_RS18195	COG0489	protein tyrosine kinase activity
EC12536_RS18195	COG3206	protein involved in exopolysaccharide biosynthesis
EC12536_RS18225	COG1253	flavin adenine dinucleotide binding
EC12536_RS18230	COG2982	Protein involved in outer membrane biogenesis
EC12536_RS18245	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EC12536_RS18250	COG0443	Heat shock 70 kDa protein
EC12536_RS18255	COG5002	protein histidine kinase activity
EC12536_RS18270	COG1301	dicarboxylic acid transport
EC12536_RS18295	COG2205	protein histidine kinase activity
EC12536_RS18300	COG0745	RESPONSE REGULATOR receiver
EC12536_RS18305	COG0826	peptidase U32
EC12536_RS18315	COG4608	Belongs to the ABC transporter superfamily
EC12536_RS18320	COG0444	Belongs to the ABC transporter superfamily
EC12536_RS18325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC12536_RS18330	COG0601	transmembrane transport
EC12536_RS18335	COG0747	negative chemotaxis
EC12536_RS18340	COG4948	Mandelate Racemase Muconate Lactonizing
EC12536_RS18345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC12536_RS18355	COG1070	Carbohydrate kinase
EC12536_RS18380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EC12536_RS18390	COG1830	Aldolase
EC12536_RS18395	COG0351	phosphomethylpyrimidine kinase
EC12536_RS18415	COG0583	DNA-binding transcription factor activity
EC12536_RS18425	COG2252	PERMEase
EC12536_RS18430	COG0583	DNA-binding transcription factor activity
EC12536_RS18435	COG5455	response to cobalt ion
EC12536_RS18455	COG4807	Protein conserved in bacteria
EC12536_RS18465	COG3275	phosphorelay sensor kinase activity
EC12536_RS18475	COG1174	glycine betaine transport
EC12536_RS18480	COG1125	glycine betaine transport
EC12536_RS18485	COG1174	glycine betaine transport
EC12536_RS18490	COG1732	Glycine betaine
EC12536_RS18495	COG1472	Belongs to the glycosyl hydrolase 3 family
EC12536_RS18500	COG0277	FAD linked oxidase domain protein
EC12536_RS18510	COG1686	Belongs to the peptidase S11 family
EC12536_RS18520	COG0586	Pfam SNARE associated Golgi protein
EC12536_RS18525	COG1538	Outer membrane efflux protein
EC12536_RS18535	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS18550	COG3659	wide pore channel activity
EC12536_RS18555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC12536_RS18565	COG1346	cytolysis
EC12536_RS18575	COG2949	membrane
EC12536_RS18585	COG1129	ABC transporter
EC12536_RS18600	COG2311	Membrane
EC12536_RS18615	COG4771	TonB-dependent receptor
EC12536_RS18620	COG0833	amino acid
EC12536_RS18625	COG0583	DNA-binding transcription factor activity
EC12536_RS18635	COG2855	membrane
EC12536_RS18645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC12536_RS18645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC12536_RS18645	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EC12536_RS18650	COG1105	Belongs to the carbohydrate kinase PfkB family
EC12536_RS18655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS18655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS18680	COG1312	Catalyzes the dehydration of D-mannonate
EC12536_RS18685	COG0246	Mannitol dehydrogenase
EC12536_RS18690	COG0523	cobalamin synthesis protein
EC12536_RS18695	COG0671	phosphoesterase, PA-phosphatase related
EC12536_RS18700	COG0791	NLP P60 protein
EC12536_RS18705	COG2200	EAL domain
EC12536_RS18710	COG4166	transmembrane transport
EC12536_RS18715	COG4174	ABC transporter (Permease)
EC12536_RS18720	COG4239	(ABC) transporter, permease
EC12536_RS18725	COG4172	Belongs to the ABC transporter superfamily
EC12536_RS18735	COG2814	Major facilitator Superfamily
EC12536_RS18740	COG1187	pseudouridine synthase activity
EC12536_RS18745	COG1061	Type III restriction enzyme res subunit
EC12536_RS18765	COG0494	nUDIX hydrolase
EC12536_RS18770	COG1349	DNA-binding transcription factor activity
EC12536_RS18800	COG0628	permease
EC12536_RS18815	COG0659	secondary active sulfate transmembrane transporter activity
EC12536_RS18820	COG2239	Acts as a magnesium transporter
EC12536_RS18825	COG4615	Cyclic peptide transporter
EC12536_RS18830	COG3145	DNA-N1-methyladenine dioxygenase activity
EC12536_RS18835	COG2169	Transcriptional regulator
EC12536_RS18835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC12536_RS18850	COG0642	Histidine kinase
EC12536_RS18850	COG2198	Histidine kinase
EC12536_RS18860	COG0784	Response regulator, receiver
EC12536_RS18860	COG2205	protein histidine kinase activity
EC12536_RS18890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC12536_RS18900	COG0584	glycerophosphoryl diester phosphodiesterase
EC12536_RS18905	COG2271	Major facilitator Superfamily
EC12536_RS18910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EC12536_RS18920	COG0247	lactate metabolic process
EC12536_RS18930	COG2271	Major facilitator Superfamily
EC12536_RS18940	COG1414	Transcriptional regulator
EC12536_RS18955	COG5464	transposase or invertase
EC12536_RS18965	COG0318	PFAM AMP-dependent synthetase and ligase
EC12536_RS18990	COG1169	isochorismate synthase
EC12536_RS18995	COG2153	protein acetylation
EC12536_RS19010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC12536_RS19015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EC12536_RS19025	COG0839	Belongs to the complex I subunit 6 family
EC12536_RS19075	COG0583	DNA-binding transcription factor activity
EC12536_RS19080	COG0436	Aminotransferase
EC12536_RS19090	COG0490	domain, Protein
EC12536_RS19090	COG0471	metal ion transport
EC12536_RS19095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC12536_RS19115	COG0857	belongs to the CobB CobQ family
EC12536_RS19115	COG0280	phosphate acetyltransferase
EC12536_RS19120	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EC12536_RS19125	COG0622	Phosphoesterase
EC12536_RS19130	COG0625	glutathione transferase activity
EC12536_RS19135	COG0625	glutathione transferase activity
EC12536_RS19140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EC12536_RS19145	COG1090	epimerase
EC12536_RS19155	COG4598	ABC transporter
EC12536_RS19160	COG4160	amino acid transport
EC12536_RS19180	COG0163	prenyltransferase activity
EC12536_RS19185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EC12536_RS19190	COG1286	toxin biosynthetic process
EC12536_RS19195	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EC12536_RS19200	COG0285	dihydrofolate synthase activity
EC12536_RS19210	COG0586	Pfam SNARE associated Golgi protein
EC12536_RS19220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC12536_RS19240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC12536_RS19255	COG3101	peptidyl-lysine hydroxylation
EC12536_RS19260	COG0730	response to heat
EC12536_RS19285	COG2062	phosphohistidine phosphatase, SixA
EC12536_RS19300	COG3691	Protein conserved in bacteria
EC12536_RS19310	COG2853	Lipoprotein
EC12536_RS19315	COG2116	formate transmembrane transporter activity
EC12536_RS19335	COG0583	DNA-binding transcription factor activity
EC12536_RS19340	COG0590	tRNA wobble adenosine to inosine editing
EC12536_RS19345	COG2807	transmembrane transport
EC12536_RS19355	COG0436	Aminotransferase
EC12536_RS19365	COG3275	phosphorelay sensor kinase activity
EC12536_RS19370	COG3279	Response regulator of the LytR AlgR family
EC12536_RS19385	COG3961	Belongs to the TPP enzyme family
EC12536_RS19390	COG0667	Aldo Keto reductase
EC12536_RS19405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EC12536_RS19410	COG2199	diguanylate cyclase activity
EC12536_RS19410	COG2200	EAL domain
EC12536_RS19425	COG3415	Transposase
EC12536_RS19430	COG3415	Transposase
EC12536_RS19465	COG0583	DNA-binding transcription factor activity
EC12536_RS19470	COG0385	Bile acid
EC12536_RS19475	COG3530	Putative quorum-sensing-regulated virulence factor
EC12536_RS19495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EC12536_RS19530	COG4319	ketosteroid isomerase
EC12536_RS19540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EC12536_RS19545	COG4208	sulfate ABC transporter
EC12536_RS19550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EC12536_RS19555	COG4150	thiosulfate binding
EC12536_RS19565	COG2837	iron assimilation
EC12536_RS19585	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC12536_RS19675	COG4810	utilization protein
EC12536_RS19685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC12536_RS19690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC12536_RS19695	COG5342	invasion associated locus B
EC12536_RS19705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC12536_RS19705	COG0493	'glutamate synthase
EC12536_RS19715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC12536_RS19725	COG1393	Belongs to the ArsC family
EC12536_RS19740	COG0400	carboxylic ester hydrolase activity
EC12536_RS19745	COG1444	tRNA N-acetyltransferase activity
EC12536_RS19750	COG2321	neutral zinc metallopeptidase
EC12536_RS19760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EC12536_RS19770	COG2716	regulation of RNA biosynthetic process
EC12536_RS19775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EC12536_RS19780	COG0628	permease
EC12536_RS19785	COG4783	chaperone-mediated protein folding
EC12536_RS19790	COG1393	Belongs to the ArsC family
EC12536_RS19805	COG2233	PERMEase
EC12536_RS19815	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS19830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EC12536_RS19845	COG2200	EAL domain
EC12536_RS19890	COG0517	IMP dehydrogenase activity
EC12536_RS19890	COG0516	GMP reductase activity
EC12536_RS19900	COG1645	bacterial-type flagellum-dependent swarming motility
EC12536_RS19940	COG2976	Protein conserved in bacteria
EC12536_RS19975	COG4953	penicillin-binding protein 1C
EC12536_RS19980	COG2373	Large extracellular alpha-helical protein
EC12536_RS19985	COG2897	thiosulfate sulfurtransferase activity
EC12536_RS20010	COG2975	iron-sulfur cluster assembly
EC12536_RS20015	COG0633	Ferredoxin
EC12536_RS20035	COG0822	iron-sulfur transferase activity
EC12536_RS20065	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EC12536_RS20070	COG3683	transport system, periplasmic component
EC12536_RS20075	COG3711	transcriptional antiterminator
EC12536_RS20080	COG2814	Major facilitator Superfamily
EC12536_RS20085	COG2017	converts alpha-aldose to the beta-anomer
EC12536_RS20090	COG0477	Major facilitator Superfamily
EC12536_RS20090	COG2814	Major facilitator Superfamily
EC12536_RS20095	COG0457	Tetratricopeptide repeat
EC12536_RS20100	COG1940	carbohydrate kinase activity
EC12536_RS20105	COG2259	Doxx family
EC12536_RS20115	COG1017	nitric oxide dioxygenase activity
EC12536_RS20115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EC12536_RS20120	COG0347	Belongs to the P(II) protein family
EC12536_RS20125	COG2204	response regulator
EC12536_RS20130	COG3170	Tfp pilus assembly protein FimV
EC12536_RS20135	COG2205	protein histidine kinase activity
EC12536_RS20145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EC12536_RS20145	COG0047	phosphoribosylformylglycinamidine synthase activity
EC12536_RS20160	COG0560	Phosphoserine phosphatase
EC12536_RS20165	COG1737	Transcriptional regulator
EC12536_RS20170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC12536_RS20180	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EC12536_RS20200	COG0681	Belongs to the peptidase S26 family
EC12536_RS20210	COG3086	response to oxidative stress
EC12536_RS20215	COG3026	antisigma factor binding
EC12536_RS20220	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EC12536_RS20235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EC12536_RS20245	COG0513	Belongs to the DEAD box helicase family
EC12536_RS20260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC12536_RS20265	COG3118	belongs to the thioredoxin family
EC12536_RS20270	COG3148	PFAM DTW domain containing protein
EC12536_RS20280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC12536_RS20285	COG5544	Lipoprotein
EC12536_RS20290	COG0477	Major facilitator Superfamily
EC12536_RS20315	COG0542	response to heat
EC12536_RS20330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EC12536_RS20335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EC12536_RS20345	COG0077	Prephenate dehydratase
EC12536_RS20345	COG1605	Chorismate mutase
EC12536_RS20355	COG0287	Prephenate dehydrogenase
EC12536_RS20355	COG1605	Chorismate mutase
EC12536_RS20360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EC12536_RS20370	COG2199	diguanylate cyclase activity
EC12536_RS20375	COG2885	chlorophyll binding
EC12536_RS20410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EC12536_RS20415	COG4137	Cytochrome C assembly protein
EC12536_RS20420	COG4536	flavin adenine dinucleotide binding
EC12536_RS20440	COG0497	DNA recombination
EC12536_RS20455	COG2867	negative regulation of translational initiation
EC12536_RS20470	COG0582	viral genome integration into host DNA
EC12536_RS20475	COG2815	serine threonine protein kinase
EC12536_RS20475	COG0515	serine threonine protein kinase
EC12536_RS20500	COG1204	response to ionizing radiation
EC12536_RS20525	COG3708	Transcriptional regulator
EC12536_RS20525	COG2207	Transcriptional regulator
EC12536_RS20530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS20565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS20570	COG1126	abc transporter atp-binding protein
EC12536_RS20575	COG0235	Class ii aldolase
EC12536_RS20585	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS20620	COG3121	Chaperone
EC12536_RS20625	COG3539	Fimbrial protein
EC12536_RS20635	COG3284	Transcriptional regulator
EC12536_RS20650	COG0640	Transcriptional regulator
EC12536_RS20655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EC12536_RS20670	COG2916	Histone family protein nucleoid-structuring protein H-NS
EC12536_RS20695	COG4575	ribosome binding
EC12536_RS20700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC12536_RS20705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EC12536_RS20720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC12536_RS20735	COG4176	ABC-type proline glycine betaine transport system permease component
EC12536_RS20745	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EC12536_RS20755	COG1846	Transcriptional regulator
EC12536_RS20760	COG1566	PFAM secretion protein HlyD family protein
EC12536_RS20765	COG2814	Major facilitator Superfamily
EC12536_RS20770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC12536_RS20790	COG1238	metal cluster binding
EC12536_RS20795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC12536_RS20800	COG2823	Periplasmic or secreted lipoprotein
EC12536_RS20830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EC12536_RS20855	COG1546	Belongs to the CinA family
EC12536_RS20860	COG0803	Belongs to the bacterial solute-binding protein 9 family
EC12536_RS20865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC12536_RS20870	COG1121	(ABC) transporter
EC12536_RS20880	COG2951	lytic endotransglycosylase activity
EC12536_RS20885	COG3730	PTS system glucitol sorbitol-specific
EC12536_RS20890	COG3732	PTS system glucitol sorbitol-specific
EC12536_RS20900	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS20905	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS20910	COG1349	DNA-binding transcription factor activity
EC12536_RS20940	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EC12536_RS20945	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EC12536_RS20950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC12536_RS20955	COG1609	Transcriptional regulator
EC12536_RS20960	COG1263	PTS System
EC12536_RS20960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS20965	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS20975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EC12536_RS20985	COG3260	NADH ubiquinone oxidoreductase 20
EC12536_RS20990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC12536_RS20995	COG3261	NADH dehydrogenase
EC12536_RS20995	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EC12536_RS21000	COG0650	Formate hydrogenlyase subunit 4
EC12536_RS21005	COG0651	ATP synthesis coupled electron transport
EC12536_RS21010	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC12536_RS21030	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EC12536_RS21035	COG0298	carbon dioxide binding
EC12536_RS21040	COG0409	Hydrogenase expression formation protein
EC12536_RS21045	COG0309	Hydrogenase expression formation protein (HypE)
EC12536_RS21055	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS21065	COG4580	involved in the transport of maltose and maltodextrins
EC12536_RS21075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS21080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS21085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS21090	COG1447	Phosphotransferase system cellobiose-specific component IIA
EC12536_RS21095	COG1940	carbohydrate kinase activity
EC12536_RS21100	COG1609	Transcriptional regulator
EC12536_RS21110	COG1121	(ABC) transporter
EC12536_RS21115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC12536_RS21120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC12536_RS21135	COG0679	Auxin Efflux Carrier
EC12536_RS21155	COG3720	iron ion transport
EC12536_RS21160	COG4558	Periplasmic binding protein
EC12536_RS21165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC12536_RS21195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EC12536_RS21200	COG0163	prenyltransferase activity
EC12536_RS21225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EC12536_RS21230	COG1388	LysM domain
EC12536_RS21230	COG4942	peptidase
EC12536_RS21290	COG2234	aminopeptidase activity
EC12536_RS21310	COG0720	synthase
EC12536_RS21315	COG0602	queuosine metabolic process
EC12536_RS21335	COG3956	TIGRFAM MazG family protein
EC12536_RS21340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC12536_RS21350	COG4999	Histidine kinase
EC12536_RS21350	COG2205	protein histidine kinase activity
EC12536_RS21350	COG3437	response regulator, receiver
EC12536_RS21350	COG3850	Histidine kinase
EC12536_RS21360	COG1929	Belongs to the glycerate kinase type-1 family
EC12536_RS21365	COG4948	Mandelate Racemase Muconate Lactonizing
EC12536_RS21370	COG4948	Mandelate Racemase Muconate Lactonizing
EC12536_RS21375	COG2271	Major facilitator Superfamily
EC12536_RS21385	COG0716	FMN binding
EC12536_RS21390	COG0564	pseudouridine synthase activity
EC12536_RS21395	COG3098	single-species biofilm formation
EC12536_RS21410	COG1611	Belongs to the LOG family
EC12536_RS21415	COG0814	amino acid
EC12536_RS21420	COG1760	l-serine dehydratase
EC12536_RS21425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EC12536_RS21435	COG0477	Major facilitator Superfamily
EC12536_RS21445	COG1464	Belongs to the NlpA lipoprotein family
EC12536_RS21450	COG2011	ABC-type metal ion transport system permease component
EC12536_RS21470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC12536_RS21485	COG1454	alcohol dehydrogenase
EC12536_RS21490	COG0235	Class ii aldolase
EC12536_RS21495	COG0738	Major facilitator superfamily
EC12536_RS21515	COG1349	DNA-binding transcription factor activity
EC12536_RS21525	COG2363	Small membrane protein
EC12536_RS21530	COG0583	DNA-binding transcription factor activity
EC12536_RS21540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EC12536_RS21545	COG2166	iron-sulfur cluster assembly
EC12536_RS21550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EC12536_RS21555	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EC12536_RS21720	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EC12536_RS21750	COG1454	alcohol dehydrogenase
EC12536_RS21750	COG1012	belongs to the aldehyde dehydrogenase family
EC12536_RS21755	COG4656	Part of a membrane complex involved in electron transport
EC12536_RS21785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EC12536_RS21790	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC12536_RS21795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EC12536_RS21795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EC12536_RS21805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EC12536_RS21810	COG1074	ATP-dependent DNA helicase activity
EC12536_RS21815	COG1025	Belongs to the peptidase M16 family
EC12536_RS21820	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EC12536_RS21825	COG4967	type IV pilus modification protein PilV
EC12536_RS21835	COG4795	General secretion pathway protein
EC12536_RS21840	COG2165	general secretion pathway protein
EC12536_RS21875	COG0861	Integral membrane protein TerC family
EC12536_RS21885	COG0667	Aldo Keto reductase
EC12536_RS21910	COG1609	Transcriptional regulator
EC12536_RS21920	COG2186	Transcriptional regulator
EC12536_RS21925	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS21930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS21935	COG1609	Transcriptional regulator
EC12536_RS21945	COG0583	DNA-binding transcription factor activity
EC12536_RS21950	COG1794	racemase activity, acting on amino acids and derivatives
EC12536_RS21955	COG1917	Cupin 2, conserved barrel domain protein
EC12536_RS21960	COG1175	transmembrane transport
EC12536_RS21965	COG0395	ABC-type sugar transport system, permease component
EC12536_RS21970	COG3842	ATPase activity
EC12536_RS22000	COG2814	Major facilitator Superfamily
EC12536_RS22005	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS22010	COG0823	Involved in the tonB-independent uptake of proteins
EC12536_RS22020	COG0183	Belongs to the thiolase family
EC12536_RS22035	COG0814	amino acid
EC12536_RS22040	COG0667	Aldo Keto reductase
EC12536_RS22090	COG0697	spore germination
EC12536_RS22095	COG1846	Transcriptional regulator
EC12536_RS22100	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EC12536_RS22110	COG0582	viral genome integration into host DNA
EC12536_RS22115	COG4974	Belongs to the 'phage' integrase family
EC12536_RS22125	COG3539	Fimbrial protein
EC12536_RS22130	COG3121	Chaperone
EC12536_RS22135	COG3188	usher protein
EC12536_RS22140	COG3539	Fimbrial protein
EC12536_RS22145	COG3539	Fimbrial protein
EC12536_RS22150	COG3539	Fimbrial protein
EC12536_RS22160	COG2388	GCN5-related N-acetyl-transferase
EC12536_RS22165	COG3592	Divergent 4Fe-4S mono-cluster
EC12536_RS22180	COG1289	transmembrane transporter activity
EC12536_RS22185	COG1538	Outer membrane efflux protein
EC12536_RS22200	COG1393	Belongs to the ArsC family
EC12536_RS22205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EC12536_RS22245	COG0667	Aldo Keto reductase
EC12536_RS22260	COG2814	Major facilitator Superfamily
EC12536_RS22270	COG4942	peptidase
EC12536_RS22295	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EC12536_RS22305	COG4974	Belongs to the 'phage' integrase family
EC12536_RS22310	COG0716	FMN binding
EC12536_RS22320	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EC12536_RS22330	COG1272	protein, Hemolysin III
EC12536_RS22340	COG1737	Transcriptional regulator
EC12536_RS22345	COG2723	6-phospho-beta-galactosidase activity
EC12536_RS22365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC12536_RS22370	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS22390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC12536_RS22395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EC12536_RS22400	COG0006	proline dipeptidase activity
EC12536_RS22420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EC12536_RS22425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC12536_RS22440	COG2968	Membrane
EC12536_RS22450	COG0668	transmembrane transport
EC12536_RS22455	COG0191	fructose-bisphosphate aldolase activity
EC12536_RS22470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC12536_RS22475	COG0501	Belongs to the peptidase M48B family
EC12536_RS22495	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
EC12536_RS22500	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS22530	COG1414	Transcriptional regulator
EC12536_RS22535	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS22550	COG2146	nitrite reductase [NAD(P)H] activity
EC12536_RS22590	COG2814	Major facilitator Superfamily
EC12536_RS22600	COG2356	endonuclease I
EC12536_RS22605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EC12536_RS22610	COG0189	ligase activity
EC12536_RS22630	COG2805	Type II/IV secretion system protein
EC12536_RS22635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EC12536_RS22640	COG0762	integral membrane protein
EC12536_RS22655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC12536_RS22665	COG3171	Protein conserved in bacteria
EC12536_RS22675	COG1194	a g-specific adenine glycosylase
EC12536_RS22690	COG2211	Major facilitator Superfamily
EC12536_RS22695	COG1982	Orn Lys Arg decarboxylase major
EC12536_RS22705	COG1811	Na channel or pump
EC12536_RS22735	COG3188	usher protein
EC12536_RS22740	COG3121	Chaperone
EC12536_RS22745	COG3121	Chaperone
EC12536_RS22760	COG3121	Chaperone
EC12536_RS22775	COG0626	cystathionine gamma-synthase activity
EC12536_RS22780	COG0583	DNA-binding transcription factor activity
EC12536_RS22800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EC12536_RS22805	COG0754	glutathionylspermidine amidase activity
EC12536_RS22815	COG0625	glutathione transferase activity
EC12536_RS22840	COG2211	Major facilitator Superfamily
EC12536_RS22845	COG0848	biopolymer transport protein
EC12536_RS22860	COG0626	cystathionine gamma-synthase activity
EC12536_RS22865	COG0586	Pfam SNARE associated Golgi protein
EC12536_RS22870	COG2207	Transcriptional regulator
EC12536_RS22875	COG1979	alcohol dehydrogenase
EC12536_RS22880	COG0656	L-ascorbic acid biosynthetic process
EC12536_RS22890	COG1032	radical SAM domain protein
EC12536_RS22895	COG2132	Multicopper oxidase
EC12536_RS22900	COG0204	Acyl-transferase
EC12536_RS22905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EC12536_RS22910	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EC12536_RS22915	COG3111	PFAM Bacterial OB fold (BOF) protein
EC12536_RS22925	COG0642	Histidine kinase
EC12536_RS22930	COG2249	NAD(P)H dehydrogenase (quinone) activity
EC12536_RS22935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EC12536_RS22945	COG3150	esterase
EC12536_RS22950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC12536_RS22955	COG3151	Protein conserved in bacteria
EC12536_RS22960	COG0494	nUDIX hydrolase
EC12536_RS22975	COG0754	glutathionylspermidine amidase activity
EC12536_RS22980	COG3384	dioxygenase
EC12536_RS22995	COG2960	long-chain fatty acid transporting porin activity
EC12536_RS23015	COG3025	triphosphatase activity
EC12536_RS23020	COG4991	sh3 domain protein
EC12536_RS23035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EC12536_RS23095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EC12536_RS23100	COG0358	DNA primase activity
EC12536_RS23105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EC12536_RS23120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EC12536_RS23155	COG2197	response regulator
EC12536_RS23160	COG2198	Histidine kinase
EC12536_RS23160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC12536_RS23160	COG0784	Response regulator, receiver
EC12536_RS23160	COG2205	protein histidine kinase activity
EC12536_RS23170	COG3247	response to pH
EC12536_RS23245	COG2376	Dihydroxyacetone kinase
EC12536_RS23250	COG1461	Dihydroxyacetone kinase
EC12536_RS23265	COG2375	cellular response to nickel ion
EC12536_RS23270	COG1695	Transcriptional regulator
EC12536_RS23320	COG0446	pyridine nucleotide-disulphide oxidoreductase
EC12536_RS23320	COG1902	pentaerythritol trinitrate reductase activity
EC12536_RS23340	COG1451	nucleotide metabolic process
EC12536_RS23345	COG0673	inositol 2-dehydrogenase activity
EC12536_RS23350	COG0861	Integral membrane protein TerC family
EC12536_RS23365	COG2721	sulfolactate sulfo-lyase activity
EC12536_RS23375	COG2271	Major facilitator Superfamily
EC12536_RS23380	COG2186	Transcriptional regulator
EC12536_RS23385	COG0586	Pfam SNARE associated Golgi protein
EC12536_RS23395	COG1422	Protein of unknown function (DUF1090)
EC12536_RS23400	COG4575	ribosome binding
EC12536_RS23405	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EC12536_RS23415	COG2259	Doxx family
EC12536_RS23420	COG0435	Glutathione S-transferase
EC12536_RS23425	COG3152	Membrane
EC12536_RS23430	COG0583	DNA-binding transcription factor activity
EC12536_RS23435	COG1741	Belongs to the pirin family
EC12536_RS23460	COG1929	Belongs to the glycerate kinase type-1 family
EC12536_RS23465	COG2084	Dehydrogenase
EC12536_RS23475	COG2271	Major facilitator Superfamily
EC12536_RS23485	COG2721	sulfolactate sulfo-lyase activity
EC12536_RS23490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS23495	COG1349	DNA-binding transcription factor activity
EC12536_RS23505	COG1105	Belongs to the carbohydrate kinase PfkB family
EC12536_RS23510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS23510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC12536_RS23510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EC12536_RS23515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS23515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS23525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS23530	COG3414	Phosphotransferase system galactitol-specific IIB component
EC12536_RS23535	COG3775	system Galactitol-specific IIC component
EC12536_RS23540	COG1063	alcohol dehydrogenase
EC12536_RS23555	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EC12536_RS23575	COG2823	Periplasmic or secreted lipoprotein
EC12536_RS23580	COG0701	Predicted permease
EC12536_RS23585	COG0702	epimerase
EC12536_RS23590	COG0693	protein deglycase activity
EC12536_RS23605	COG3153	acetyltransferase
EC12536_RS23610	COG3154	lipid carrier protein
EC12536_RS23615	COG0826	peptidase U32
EC12536_RS23620	COG0826	peptidase U32
EC12536_RS23625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EC12536_RS23630	COG0814	amino acid
EC12536_RS23680	COG0195	Participates in both transcription termination and antitermination
EC12536_RS23720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EC12536_RS23730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EC12536_RS23735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC12536_RS23745	COG1534	Rna-binding protein
EC12536_RS23755	COG2027	D-alanyl-D-alanine carboxypeptidase
EC12536_RS23765	COG0697	spore germination
EC12536_RS23780	COG0142	geranyltranstransferase activity
EC12536_RS23785	COG3423	Transcriptional regulator
EC12536_RS23795	COG5007	Belongs to the BolA IbaG family
EC12536_RS23800	COG3113	response to antibiotic
EC12536_RS23805	COG2854	intermembrane phospholipid transfer
EC12536_RS23810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EC12536_RS23815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EC12536_RS23820	COG1127	ABC transporter
EC12536_RS23830	COG0530	calcium, potassium:sodium antiporter activity
EC12536_RS23840	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EC12536_RS23845	COG3117	lipopolysaccharide transmembrane transporter activity
EC12536_RS23850	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EC12536_RS23855	COG1137	ATPase activity
EC12536_RS23860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EC12536_RS23865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EC12536_RS23870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS23880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EC12536_RS23885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC12536_RS23890	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EC12536_RS23895	COG2198	Histidine kinase
EC12536_RS23895	COG5002	protein histidine kinase activity
EC12536_RS23895	COG0784	Response regulator, receiver
EC12536_RS23900	COG1312	Catalyzes the dehydration of D-mannonate
EC12536_RS23905	COG1063	alcohol dehydrogenase
EC12536_RS23910	COG2271	Major facilitator Superfamily
EC12536_RS23915	COG1242	4 iron, 4 sulfur cluster binding
EC12536_RS23920	COG0069	glutamate synthase activity
EC12536_RS23920	COG0067	glutamate synthase
EC12536_RS23920	COG0070	glutamate synthase
EC12536_RS23925	COG0493	'glutamate synthase
EC12536_RS23935	COG2969	positive regulation of protein catabolic process
EC12536_RS23940	COG0625	glutathione transferase activity
EC12536_RS23960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EC12536_RS23965	COG3105	Protein conserved in bacteria
EC12536_RS23970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC12536_RS23975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC12536_RS24000	COG2732	(Barnase) inhibitor
EC12536_RS24005	COG1289	transmembrane transporter activity
EC12536_RS24020	COG0583	DNA-binding transcription factor activity
EC12536_RS24025	COG0312	modulator of DNA gyrase
EC12536_RS24030	COG3164	Protein of unknown function
EC12536_RS24035	COG1530	ribonuclease E activity
EC12536_RS24045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EC12536_RS24050	COG1792	Involved in formation and maintenance of cell shape
EC12536_RS24055	COG1077	Cell shape determining protein MreB Mrl
EC12536_RS24060	COG2199	diguanylate cyclase activity
EC12536_RS24060	COG2200	EAL domain
EC12536_RS24085	COG0511	ligase activity, forming carbon-carbon bonds
EC12536_RS24090	COG0439	Biotin carboxylase
EC12536_RS24095	COG3924	membrane
EC12536_RS24100	COG4145	pantothenate transmembrane transporter activity
EC12536_RS24125	COG1309	transcriptional regulator
EC12536_RS24130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC12536_RS24135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC12536_RS24170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EC12536_RS24190	COG0551	DNA topoisomerase type I activity
EC12536_RS24200	COG0758	DNA mediated transformation
EC12536_RS24230	COG3036	rescue of stalled ribosome
EC12536_RS24235	COG0789	Transcriptional regulator
EC12536_RS24250	COG0202	RNA polymerase activity
EC12536_RS24275	COG0201	protein transport
EC12536_RS24340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EC12536_RS24355	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EC12536_RS24380	COG0051	transcription antitermination factor activity, RNA binding
EC12536_RS24435	COG2964	Protein conserved in bacteria
EC12536_RS24440	COG0545	Peptidyl-prolyl cis-trans isomerase
EC12536_RS24450	COG1047	Peptidyl-prolyl cis-trans
EC12536_RS24455	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EC12536_RS24470	COG0488	(ABC) transporter
EC12536_RS24480	COG0429	hydrolase of the alpha beta-hydrolase fold
EC12536_RS24490	COG3954	Phosphoribulokinase
EC12536_RS24495	COG1765	OsmC-like protein
EC12536_RS24505	COG1289	transmembrane transporter activity
EC12536_RS24510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC12536_RS24535	COG0738	Major facilitator superfamily
EC12536_RS24540	COG0402	S-adenosylhomocysteine deaminase activity
EC12536_RS24545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EC12536_RS24570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC12536_RS24575	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EC12536_RS24580	COG3266	domain, Protein
EC12536_RS24600	COG4796	Type ii and iii secretion system protein
EC12536_RS24625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EC12536_RS24630	COG0494	nUDIX hydrolase
EC12536_RS24640	COG1011	Hydrolase
EC12536_RS24645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EC12536_RS24670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC12536_RS24675	COG2183	response to ionizing radiation
EC12536_RS24680	COG1918	ferrous iron import across plasma membrane
EC12536_RS24705	COG1040	competence protein
EC12536_RS24715	COG2610	gluconate transmembrane transporter activity
EC12536_RS24720	COG1640	4-alpha-glucanotransferase
EC12536_RS24725	COG0058	SHG alpha-glucan phosphorylase activity
EC12536_RS24740	COG1349	DNA-binding transcription factor activity
EC12536_RS24755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EC12536_RS24770	COG0058	SHG alpha-glucan phosphorylase activity
EC12536_RS24795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC12536_RS24805	COG2610	gluconate transmembrane transporter activity
EC12536_RS24810	COG3265	gluconokinase activity
EC12536_RS24815	COG1609	Transcriptional regulator
EC12536_RS24820	COG1741	Belongs to the pirin family
EC12536_RS24825	COG0673	inositol 2-dehydrogenase activity
EC12536_RS24835	COG1247	-acetyltransferase
EC12536_RS24840	COG0405	Gamma-glutamyltransferase
EC12536_RS24850	COG0584	glycerophosphoryl diester phosphodiesterase
EC12536_RS24900	COG0559	Belongs to the binding-protein-dependent transport system permease family
EC12536_RS24905	COG0683	leucine binding
EC12536_RS24920	COG0683	leucine binding
EC12536_RS24930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EC12536_RS24945	COG2177	Part of the ABC transporter FtsEX involved in
EC12536_RS24950	COG2884	Cell division ATP-binding protein ftsE
EC12536_RS24955	COG0552	protein localization to endoplasmic reticulum
EC12536_RS24960	COG0742	ribosomal rna small subunit methyltransferase
EC12536_RS24965	COG3776	membrane
EC12536_RS24975	COG3714	YhhN family
EC12536_RS24990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EC12536_RS25000	COG0477	Major facilitator Superfamily
EC12536_RS25005	COG0628	permease
EC12536_RS25045	COG3479	Phenolic acid decarboxylase
EC12536_RS25060	COG0747	negative chemotaxis
EC12536_RS25065	COG0601	transmembrane transport
EC12536_RS25070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC12536_RS25080	COG1124	(ABC) transporter
EC12536_RS25090	COG2239	Acts as a magnesium transporter
EC12536_RS25095	COG2081	HI0933 family
EC12536_RS25100	COG0306	phosphate transporter
EC12536_RS25110	COG0589	response to stress
EC12536_RS25130	COG0671	phosphoesterase, PA-phosphatase related
EC12536_RS25135	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EC12536_RS25140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC12536_RS25150	COG1454	alcohol dehydrogenase
EC12536_RS25160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC12536_RS25165	COG1028	Short-chain dehydrogenase reductase Sdr
EC12536_RS25170	COG0583	DNA-binding transcription factor activity
EC12536_RS25175	COG1295	ribonuclease BN
EC12536_RS25180	COG0477	Major facilitator Superfamily
EC12536_RS25185	COG2982	Protein involved in outer membrane biogenesis
EC12536_RS25200	COG0612	Peptidase, M16
EC12536_RS25210	COG2199	diguanylate cyclase activity
EC12536_RS25210	COG2200	EAL domain
EC12536_RS25215	COG0457	Tetratricopeptide repeat
EC12536_RS25215	COG3118	belongs to the thioredoxin family
EC12536_RS25220	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EC12536_RS25225	COG1215	transferase activity, transferring glycosyl groups
EC12536_RS25255	COG2194	sulfuric ester hydrolase activity
EC12536_RS25270	COG0457	Tetratricopeptide repeat
EC12536_RS25275	COG1215	transferase activity, transferring glycosyl groups
EC12536_RS25285	COG2894	cell division
EC12536_RS25300	COG4608	Belongs to the ABC transporter superfamily
EC12536_RS25305	COG0444	Belongs to the ABC transporter superfamily
EC12536_RS25310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EC12536_RS25315	COG0601	transmembrane transport
EC12536_RS25320	COG0747	negative chemotaxis
EC12536_RS25355	COG2223	nitrite transmembrane transporter activity
EC12536_RS25360	COG5571	outer membrane autotransporter
EC12536_RS25365	COG2818	Glycosylase
EC12536_RS25370	COG0456	acetyltransferase
EC12536_RS25375	COG0243	molybdopterin cofactor binding
EC12536_RS25380	COG2885	chlorophyll binding
EC12536_RS25385	COG1609	Transcriptional regulator
EC12536_RS25395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC12536_RS25420	COG2814	Major facilitator Superfamily
EC12536_RS25425	COG2944	sequence-specific DNA binding
EC12536_RS25430	COG1278	Cold shock
EC12536_RS25435	COG0488	(ABC) transporter
EC12536_RS25465	COG3274	enterobacterial common antigen metabolic process
EC12536_RS25470	COG4682	membrane
EC12536_RS25475	COG4682	membrane
EC12536_RS25495	COG4213	ABC transporter substrate-binding protein
EC12536_RS25505	COG4214	carbohydrate transport
EC12536_RS25510	COG1609	Transcriptional regulator
EC12536_RS25510	COG2207	Transcriptional regulator
EC12536_RS25515	COG2992	FlgJ-related protein
EC12536_RS25520	COG0366	Alpha amylase catalytic
EC12536_RS25525	COG3977	Valine--pyruvate aminotransferase
EC12536_RS25530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EC12536_RS25535	COG1414	Transcriptional regulator
EC12536_RS25540	COG3276	selenocysteine insertion sequence binding
EC12536_RS25550	COG0625	glutathione transferase activity
EC12536_RS25555	COG1566	PFAM secretion protein HlyD family protein
EC12536_RS25575	COG3722	fumarate hydratase activity
EC12536_RS25595	COG2186	Transcriptional regulator
EC12536_RS25605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EC12536_RS25625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EC12536_RS25630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EC12536_RS25640	COG4942	peptidase
EC12536_RS25645	COG2861	carbohydrate metabolic process
EC12536_RS25650	COG0463	Glycosyl transferase, family 2
EC12536_RS25660	COG0156	8-amino-7-oxononanoate synthase activity
EC12536_RS25675	COG0859	PFAM glycosyl transferase family 9
EC12536_RS25700	COG0859	PFAM glycosyl transferase family 9
EC12536_RS25710	COG0438	transferase activity, transferring glycosyl groups
EC12536_RS25715	COG1216	Glycosyl transferase, family 2
EC12536_RS25720	COG1519	Transferase
EC12536_RS25755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EC12536_RS25780	COG0842	Transport permease protein
EC12536_RS25785	COG1131	(ABC) transporter
EC12536_RS25805	COG1561	YicC-like family, N-terminal region
EC12536_RS25810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EC12536_RS25815	COG2169	Transcriptional regulator
EC12536_RS25815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC12536_RS25825	COG2860	membrane
EC12536_RS25845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC12536_RS25850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC12536_RS25855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EC12536_RS25860	COG1494	fructose-1,6-bisphosphatase
EC12536_RS25870	COG3152	Membrane
EC12536_RS25895	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EC12536_RS25915	COG0786	glutamate:sodium symporter activity
EC12536_RS25920	COG2233	PERMEase
EC12536_RS25925	COG2982	Protein involved in outer membrane biogenesis
EC12536_RS25930	COG1263	PTS System
EC12536_RS25930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS25935	COG1486	melibiose metabolic process
EC12536_RS25945	COG1501	Belongs to the glycosyl hydrolase 31 family
EC12536_RS25950	COG2211	Major facilitator Superfamily
EC12536_RS25985	COG1064	alcohol dehydrogenase
EC12536_RS25995	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EC12536_RS26010	COG1464	Belongs to the NlpA lipoprotein family
EC12536_RS26035	COG0583	DNA-binding transcription factor activity
EC12536_RS26070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC12536_RS26080	COG2814	Major facilitator Superfamily
EC12536_RS26090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EC12536_RS26090	COG1263	PTS System
EC12536_RS26095	COG0697	spore germination
EC12536_RS26110	COG2828	Protein conserved in bacteria
EC12536_RS26115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EC12536_RS26120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EC12536_RS26125	COG0583	DNA-binding transcription factor activity
EC12536_RS26130	COG3384	dioxygenase
EC12536_RS26140	COG1609	Transcriptional regulator
EC12536_RS26150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS26150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EC12536_RS26155	COG1447	Phosphotransferase system cellobiose-specific component IIA
EC12536_RS26160	COG4580	involved in the transport of maltose and maltodextrins
EC12536_RS26185	COG2188	Transcriptional regulator
EC12536_RS26230	COG2271	Major facilitator Superfamily
EC12536_RS26240	COG2197	response regulator
EC12536_RS26245	COG0440	acetolactate synthase activity
EC12536_RS26250	COG0028	Belongs to the TPP enzyme family
EC12536_RS26275	COG2814	Major facilitator Superfamily
EC12536_RS26280	COG0583	DNA-binding transcription factor activity
EC12536_RS26285	COG2610	gluconate transmembrane transporter activity
EC12536_RS26305	COG2149	membrane
EC12536_RS26320	COG2188	Transcriptional regulator
EC12536_RS26345	COG5645	(Lipo)protein
EC12536_RS26350	COG0823	Involved in the tonB-independent uptake of proteins
EC12536_RS26355	COG2271	Major facilitator Superfamily
EC12536_RS26365	COG0800	Aldolase
EC12536_RS26370	COG3734	2-keto-3-deoxy-galactonokinase
EC12536_RS26375	COG2186	Transcriptional regulator
EC12536_RS26390	COG0561	phosphatase activity
EC12536_RS26395	COG0187	DNA topoisomerase II activity
EC12536_RS26450	COG0583	DNA-binding transcription factor activity
EC12536_RS26575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC12536_RS26605	COG2003	Belongs to the UPF0758 family