locus-tag class description FZN31_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FZN31_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FZN31_RS00025 ENOG4105VP5 Bacterial protein of unknown function (DUF937) FZN31_RS00030 ENOG410667J hydrolase FZN31_RS00035 ENOG410657R replicase EC 2.7 FZN31_RS00040 ENOG4105EMF GntR family transcriptional regulator FZN31_RS00045 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 FZN31_RS00050 ENOG4108RTU Aldolase FZN31_RS00060 ENOG4105DJB Major Facilitator Superfamily FZN31_RS00070 ENOG4105D99 atp gtp-binding protein FZN31_RS00075 ENOG4105R2A (LipO)protein FZN31_RS00095 ENOG4105FDP GntR family transcriptional regulator FZN31_RS00100 ENOG4105CI1 PTS System FZN31_RS00105 ENOG4105F8D glycoside hydrolase family 4 FZN31_RS00110 ENOG4108AHD Transcriptional regulator FZN31_RS00115 ENOG4107RUZ Sss sodium solute transporter superfamily FZN31_RS00120 ENOG4105CBG Sulfatase FZN31_RS00125 ENOG4106DRA Inner membrane protein YidI FZN31_RS00130 ENOG4105VG5 Membrane FZN31_RS00135 ENOG4105JP4 Inner membrane protein yidG FZN31_RS00140 ENOG4105J13 transcriptional regulator FZN31_RS00145 ENOG4105E5M Multidrug resistance protein D FZN31_RS00160 ENOG4105C7K acetolactate synthase FZN31_RS00165 ENOG4105M71 acetolactate synthase 1 regulatory subunit FZN31_RS00180 ENOG4108KX4 response regulator FZN31_RS00185 ENOG4105BZU Histidine kinase FZN31_RS00190 ENOG4105CXY transporter FZN31_RS00195 ENOG4105CXY transporter FZN31_RS00205 ENOG4105C7N Xanthine uracil vitamin C permease FZN31_RS00210 ENOG4108SAJ Protein of unknown function (DUF1198) FZN31_RS00235 ENOG4108YAB Invasion protein FZN31_RS00240 ENOG4105IBT Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC FZN31_RS00265 ENOG4105T8A Uncharacterized protein YicS FZN31_RS00270 ENOG4105D01 (LipO)protein FZN31_RS00275 ENOG4108UZ3 Transporter FZN31_RS00280 ENOG4105S8Q sugar efflux transporter FZN31_RS00310 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FZN31_RS00315 ENOG4106WJE Protein of unknown function (DUF987) FZN31_RS00320 ENOG4108YGG dna repair protein FZN31_RS00325 ENOG4105MFG Antirestriction protein FZN31_RS00330 ENOG4106H6R UPF0380 protein FZN31_RS00345 ENOG4108KZE transcriptional regulator FZN31_RS00350 ENOG4105TS0 gtp-binding protein FZN31_RS00400 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein FZN31_RS00410 ENOG41090WB Transposase is3 is911 FZN31_RS00440 ENOG4107SCJ type I restriction enzyme EcoKI subunit R FZN31_RS00455 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FZN31_RS00475 ENOG4105T40 surface antigen msp4 family protein FZN31_RS00480 ENOG4108I6E Sulfatase FZN31_RS00490 ENOG4105W1Y Transcriptional regulator FZN31_RS00495 ENOG4108VSE mercuric transport protein FZN31_RS00545 ENOG4105BZU Histidine kinase FZN31_RS00635 ENOG4105DFP Integrase FZN31_RS00645 ENOG4105CT4 transporter FZN31_RS00650 ENOG4105CJQ hydrolase, family 31 FZN31_RS00655 ENOG4105ETD TRANSCRIPTIONal FZN31_RS00660 ENOG4105DM4 PTS System FZN31_RS00665 ENOG4108YRF PTS System FZN31_RS00670 ENOG4105DM4 PTS System FZN31_RS00675 ENOG4105D2N Aldolase FZN31_RS00685 ENOG4105DKQ ROK family FZN31_RS00695 ENOG4105JV1 AsmA family FZN31_RS00700 ENOG4105C2W permease FZN31_RS00705 ENOG4105D6U Sodium Glutamate Symporter FZN31_RS00710 ENOG4105CB5 ATP-dependent DNA helicase recG FZN31_RS00715 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase FZN31_RS00720 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FZN31_RS00725 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) FZN31_RS00730 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FZN31_RS00735 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) FZN31_RS00740 ENOG4105EN6 Membrane FZN31_RS00745 ENOG4105F5P DNA-damage-inducible protein d FZN31_RS00750 ENOG4105DSJ YicC domain protein FZN31_RS00760 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FZN31_RS00765 ENOG4107RRE RNA-directed DNA polymerase FZN31_RS00780 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FZN31_RS00795 ENOG4105W0E 50S ribosomal protein L33 FZN31_RS00810 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FZN31_RS00815 ENOG4105DKP glycosyl transferase, family 9 FZN31_RS00820 ENOG4107RJ7 Glycosyl transferase (Group 1 FZN31_RS00825 ENOG4107543 (lipo)polysaccharide FZN31_RS00830 ENOG4106AH0 Glycosyl Transferase FZN31_RS00835 ENOG4105X1N Glycosyl transferase family 8 FZN31_RS00845 ENOG4105X1N Glycosyl transferase family 8 FZN31_RS00850 ENOG4105K64 Glycosyl transferase, family 2 FZN31_RS00855 ENOG41068PG O-Antigen polymerase FZN31_RS00860 ENOG4105D16 lipopolysaccharide heptosyltransferase i FZN31_RS00865 ENOG4105XA0 heptosyltransferase ii FZN31_RS00875 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FZN31_RS00885 ENOG4105K64 Glycosyl transferase, family 2 FZN31_RS00890 ENOG4105PXI polysaccharide deacetylase FZN31_RS00895 ENOG41063SB peptidase FZN31_RS00905 ENOG4107YZP Rhodanese domain protein FZN31_RS00910 ENOG4105VW4 glutaredoxin 3 FZN31_RS00925 ENOG4105D7W serine acetyltransferase FZN31_RS00930 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FZN31_RS00940 ENOG41073TP transcriptional regulator FZN31_RS00945 ENOG4105DAA L-lactate FZN31_RS00960 ENOG4108YYI Protein of unknown function (DUF2810) FZN31_RS00965 ENOG41060ND LF82 chromosome, complete sequence FZN31_RS00970 ENOG4105E61 Mannitol repressor protein FZN31_RS00980 ENOG4105CTS PTS system mannitol-specific FZN31_RS00985 ENOG4105FP6 Protein of unknown function (DUF3302) FZN31_RS00990 ENOG4105EFX secretion protein, HlyD family FZN31_RS01015 ENOG4105NUP lyase containing HEAT-repeat FZN31_RS01025 ENOG41079JQ Membrane FZN31_RS01030 ENOG4105CNA YD repeat protein FZN31_RS01035 ENOG4108U78 Glutathione S-transferase FZN31_RS01040 ENOG4105C1Y Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity) FZN31_RS01045 ENOG4105EM7 Selenocysteine-specific translation elongation factor FZN31_RS01050 ENOG4105C0A alcohol dehydrogenase FZN31_RS01055 ENOG4105C26 Dehydrogenase FZN31_RS01065 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FZN31_RS01075 ENOG4105KK7 inner membrane protein YiaW FZN31_RS01080 ENOG4105EFX secretion protein, HlyD family FZN31_RS01085 ENOG4108Q2M Transcriptional regulator FZN31_RS01090 ENOG4105GNX MltA-interacting MipA family protein FZN31_RS01100 ENOG4105CT4 transporter FZN31_RS01110 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FZN31_RS01115 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase FZN31_RS01120 ENOG4105H6Q decarboxylase FZN31_RS01125 ENOG4105CMG Carbohydrate kinase FZN31_RS01130 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FZN31_RS01135 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FZN31_RS01140 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter FZN31_RS01145 ENOG4108R66 Conserved Protein FZN31_RS01155 ENOG4105J4Q Transcriptional regulator FZN31_RS01160 ENOG4108XIB electron transport protein ysaA FZN31_RS01165 ENOG4105JKW Valine--pyruvate aminotransferase FZN31_RS01170 ENOG4107T9C Alpha amylase catalytic region FZN31_RS01175 ENOG4108UR8 BAX protein FZN31_RS01180 ENOG4105T16 Transcriptional regulator (AraC family) FZN31_RS01185 ENOG4107RNG ABC transporter FZN31_RS01190 ENOG4105C2J ABC transporter FZN31_RS01195 ENOG4105DFW ABC transporter FZN31_RS01205 ENOG4105CMG Carbohydrate kinase FZN31_RS01210 ENOG410688U Inner membrane protein yiaB FZN31_RS01215 ENOG4108Z12 YiaAB two helix domain-containing protein FZN31_RS01220 ENOG4105MEV Acyl-transferase FZN31_RS01230 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FZN31_RS01240 ENOG41060TC Hok gef cell toxic protein FZN31_RS01245 ENOG4105VEQ Cold shock protein FZN31_RS01250 ENOG4105MVF Transcriptional regulator FZN31_RS01255 ENOG4106JH6 (LipO)protein FZN31_RS01265 ENOG4108ZG0 Ompa motb domain protein FZN31_RS01270 ENOG4107QY8 reductase FZN31_RS01275 ENOG4105HNP -acetyltransferase FZN31_RS01280 ENOG4108R3E Dna-3-methyladenine glycosylase i FZN31_RS01285 ENOG4105EAX Putative lipase FZN31_RS01290 ENOG4105FCD Major Facilitator FZN31_RS01295 ENOG4105DIJ Phosphoethanolamine transferase FZN31_RS01315 ENOG4105DEF Extracellular solute-binding protein, family 5 FZN31_RS01320 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FZN31_RS01325 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FZN31_RS01330 ENOG4105C3U ABC transporter FZN31_RS01335 ENOG4108JQ7 (ABC) transporter FZN31_RS01340 ENOG4105C44 Serine transporter FZN31_RS01370 ENOG4105D1V cellulose synthase operon protein YhjU FZN31_RS01375 ENOG4105WQA Cellulose biosynthesis protein BcsF FZN31_RS01380 ENOG4105U74 cellulose biosynthesis protein BcsE FZN31_RS01385 ENOG410661M cytoplasmic protein FZN31_RS01395 ENOG4107QZ7 Cellulose synthase catalytic subunit FZN31_RS01400 ENOG4107EEX Cellulose synthase regulator protein FZN31_RS01405 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) FZN31_RS01410 ENOG4105EJG cellulose synthase FZN31_RS01415 ENOG4105BZU Histidine kinase FZN31_RS01425 ENOG4105CS0 peptidase FZN31_RS01435 ENOG4105CMB EAL domain-containing protein FZN31_RS01440 ENOG41066T0 asmA family FZN31_RS01445 ENOG4105CSH Transporter FZN31_RS01450 ENOG4107H3J ribonuclease FZN31_RS01455 ENOG4105CBN LysR family transcriptional regulator FZN31_RS01460 ENOG4106S2D Transcriptional regulator FZN31_RS01465 ENOG4105E53 ec 3.2.1.28 FZN31_RS01470 ENOG4105CA0 peroxidase FZN31_RS01475 ENOG4105CVK Glutamate decarboxylase FZN31_RS01480 ENOG4108NKV transcriptional regulator FZN31_RS01485 ENOG4105D3F AraC Family Transcriptional Regulator FZN31_RS01490 ENOG4105BZS acriflavin resistance protein FZN31_RS01495 ENOG4105C1P efflux transporter, rnd family, mfp subunit FZN31_RS01505 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci FZN31_RS01510 ENOG4108YK4 Acid-resistance membrane protein FZN31_RS01515 ENOG41060V2 Acid-resistance protein FZN31_RS01520 ENOG4105XXV Acid-resistance protein FZN31_RS01525 ENOG4105KT7 mgtC SapB transporter FZN31_RS01530 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS01535 ENOG4105EHG Permease protein FZN31_RS01545 ENOG41090JE Utilization Protein FZN31_RS01550 ENOG4105D4P Coproporphyrinogen iii oxidase FZN31_RS01555 ENOG4107R4I Periplasmic binding protein FZN31_RS01560 ENOG4107ENK receptor FZN31_RS01565 ENOG4106QJH hemin transport protein FZN31_RS01575 ENOG4105Y4Z Outer Membrane Lipoprotein FZN31_RS01585 ENOG4105K89 arsenate reductase FZN31_RS01590 ENOG4107R5R arsenical pump membrane protein FZN31_RS01595 ENOG4105KBH arsR family transcriptional regulator FZN31_RS01605 ENOG4105DC8 reductase FZN31_RS01610 ENOG4105D6S protein involved in catabolism of external DNA FZN31_RS01615 ENOG4105DGW oligopeptidase A FZN31_RS01625 ENOG4105DUX Transporter FZN31_RS01630 ENOG4108M6U Universal stress protein A FZN31_RS01640 ENOG4105CJ3 phosphate transporter FZN31_RS01645 ENOG4105CBX hi0933 family FZN31_RS01650 ENOG4107UNS conserved inner membrane protein FZN31_RS01665 ENOG4105D0S secretion protein (HlyD FZN31_RS01670 ENOG4105CJ1 ABC, transporter FZN31_RS01675 ENOG4105CMI transporter FZN31_RS01685 ENOG4105NUP lyase containing HEAT-repeat FZN31_RS01695 ENOG4105CNA YD repeat protein FZN31_RS01710 ENOG4106R09 FZN31_RS01715 ENOG4105CNA YD repeat protein FZN31_RS01725 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS01730 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS01735 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FZN31_RS01740 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FZN31_RS01745 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FZN31_RS01750 ENOG4107YAK holo-(acyl carrier protein) synthase 2 FZN31_RS01755 ENOG4105DSF transport protein FZN31_RS01760 ENOG4105F9N Major Facilitator Superfamily FZN31_RS01765 ENOG4108W1V Lipoprotein FZN31_RS01770 ENOG4105EX9 Membrane FZN31_RS01790 ENOG4107FS9 Membrane FZN31_RS01800 ENOG4105MG3 Membrane FZN31_RS01805 ENOG4106H78 methyltransferase FZN31_RS01810 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FZN31_RS01815 ENOG4105CAK Cell division ATP-binding protein ftsE FZN31_RS01820 ENOG4105CRP Part of the ABC transporter FtsEX involved in FZN31_RS01825 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FZN31_RS01830 ENOG4105CP9 extracellular ligand-binding receptor FZN31_RS01835 ENOG4105U59 -acetyltransferase FZN31_RS01840 ENOG4105CP9 extracellular ligand-binding receptor FZN31_RS01845 ENOG4105C32 Amino acid ABC transporter (Permease) FZN31_RS01850 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FZN31_RS01855 ENOG4105C0Z ABC transporter FZN31_RS01860 ENOG4108IV0 ABC, transporter FZN31_RS01865 ENOG4105BZ7 extracellular solute-binding protein family 1 FZN31_RS01870 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component FZN31_RS01875 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FZN31_RS01885 ENOG4107T6V glycerophosphoryl diester phosphodiesterase FZN31_RS01890 ENOG4105WC8 Conserved Protein FZN31_RS01895 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FZN31_RS01900 ENOG4105WCN acetyltransferase FZN31_RS01905 ENOG4105D9R oxidoreductase FZN31_RS01915 ENOG4105DIQ Transcriptional regulator FZN31_RS01920 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FZN31_RS01925 ENOG4105C6Z Gluconate FZN31_RS01930 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FZN31_RS01935 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FZN31_RS01940 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) FZN31_RS01960 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FZN31_RS01980 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FZN31_RS01995 ENOG4105E98 transcriptional regulator DeoR family FZN31_RS02000 ENOG4105CYB regulatoR FZN31_RS02005 ENOG4105E0Y RtcB Protein FZN31_RS02020 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) FZN31_RS02025 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) FZN31_RS02030 ENOG4105C6Z Gluconate FZN31_RS02040 ENOG4105MJ2 Competence protein FZN31_RS02050 ENOG4105DNE Transposase FZN31_RS02060 ENOG4105CE1 Ferrous iron transport protein b FZN31_RS02065 ENOG4105XFK Ferrous iron transport protein A FZN31_RS02070 ENOG4105BZM domain protein FZN31_RS02075 ENOG4108RRZ Transcription elongation factor GreB FZN31_RS02080 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FZN31_RS02085 ENOG4105E0F Histidine kinase FZN31_RS02110 ENOG4108MAJ Membrane FZN31_RS02120 ENOG4105VEJ Heat shock protein FZN31_RS02125 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FZN31_RS02130 ENOG4105DQY intracellular growth attenuator FZN31_RS02135 ENOG4107RK2 ADP-ribose diphosphatase NudE FZN31_RS02140 ENOG4108JQC penicillin-binding protein 1A FZN31_RS02145 ENOG4108U1Q Pilus assembly protein FZN31_RS02150 ENOG41065NF Fimbrial assembly family protein FZN31_RS02155 ENOG4105XPX DNA utilization protein HofO FZN31_RS02160 ENOG4105ITY Required for the use of extracellular DNA as a nutrient FZN31_RS02165 ENOG4105E4G Type IV pilus FZN31_RS02180 ENOG4105EGB membrane protein DamX FZN31_RS02185 ENOG4105DFE Dna adenine methylase FZN31_RS02190 ENOG4105DJV ribulose-phosphate 3-epimerase FZN31_RS02195 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FZN31_RS02200 ENOG4105C31 Tryptophanyl-tRNA synthetase FZN31_RS02205 ENOG4108M21 FZN31_RS02210 ENOG4105RMW regulation of transcription, DNA-dependent FZN31_RS02215 ENOG4108626 Racemase FZN31_RS02220 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FZN31_RS02225 ENOG41080QX K07048 phosphotriesterase-related protein FZN31_RS02230 ENOG4105MUZ Protein of unknown function DUF2620 FZN31_RS02235 ENOG4106M0N transport system permease protein FZN31_RS02240 ENOG4106PKC pyridoxal phosphate binding FZN31_RS02245 ENOG4105VYH FZN31_RS02255 ENOG4107V9H nitrite transporter FZN31_RS02260 ENOG4105WZK nitrite reductase NADPH small subunit FZN31_RS02265 ENOG4107QZF nitrite reductase NADPH large subunit FZN31_RS02275 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FZN31_RS02280 ENOG4106195 uncharacterized protein yhfG FZN31_RS02285 ENOG4105MZU cell filamentation protein FZN31_RS02290 ENOG4105DDQ anthranilate synthase FZN31_RS02295 ENOG4105C8Y Acetylornithine aminotransferase FZN31_RS02300 ENOG410613R integral membrane protein, YccS YhfK family FZN31_RS02305 ENOG4107RYR Transcriptional regulator, Crp Fnr family FZN31_RS02310 ENOG4108UKZ OsmC family FZN31_RS02315 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) FZN31_RS02325 ENOG4105DNZ Alpha Beta Hydrolase FZN31_RS02330 ENOG4105C5H ABC transporter FZN31_RS02345 ENOG4105VKU nucleicacid-binding protein FZN31_RS02350 ENOG4108YZY peptidylprolyl cis-trans isomerase FZN31_RS02360 ENOG4108V1T peptidylprolyl cis-trans isomerase FZN31_RS02365 ENOG4105WWK YheO domain protein FZN31_RS02405 ENOG4105W53 bacterioferritin-associated ferredoxin FZN31_RS02410 ENOG4108UQY Iron-storage protein FZN31_RS02430 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FZN31_RS02435 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FZN31_RS02445 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FZN31_RS02450 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FZN31_RS02455 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FZN31_RS02460 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FZN31_RS02470 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FZN31_RS02480 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FZN31_RS02495 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FZN31_RS02505 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FZN31_RS02510 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FZN31_RS02520 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FZN31_RS02525 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FZN31_RS02530 ENOG41067V7 50S ribosomal protein L36 FZN31_RS02535 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FZN31_RS02545 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FZN31_RS02550 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FZN31_RS02560 ENOG4105VTS DnaJ-like, subfamily C FZN31_RS02565 ENOG4105W1Y Transcriptional regulator FZN31_RS02570 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system FZN31_RS02580 ENOG4105C1A potassium transporter peripheral membrane FZN31_RS02600 ENOG4105C79 DNA protecting protein DprA FZN31_RS02610 ENOG4108WI1 Dna topoisomerase FZN31_RS02625 ENOG4105SG3 Protein of unknown function (DUF1488) FZN31_RS02630 ENOG4108Z0R Transferase FZN31_RS02670 ENOG4105CDA abc transporter atp-binding protein FZN31_RS02675 ENOG4105DRP amino acid AbC transporter FZN31_RS02680 ENOG4105EZ7 amino acid ABC transporter FZN31_RS02690 ENOG4105XCM membrane LIPOPROTEIN FZN31_RS02695 ENOG4105BZS acriflavin resistance protein FZN31_RS02700 ENOG4105C1P efflux transporter, rnd family, mfp subunit FZN31_RS02705 ENOG4108XG4 DNA-binding transcriptional regulator FZN31_RS02710 ENOG41061ME transport protein FZN31_RS02715 ENOG4105CEC DNA methylase N-4 N-6 FZN31_RS02720 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FZN31_RS02725 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FZN31_RS02735 ENOG4108IA2 Sodium pantothenate symporter FZN31_RS02740 ENOG4105RG0 Membrane FZN31_RS02745 ENOG4107UEK pfkb domain protein FZN31_RS02750 ENOG4105E98 transcriptional regulator DeoR family FZN31_RS02755 ENOG4105D2N Aldolase FZN31_RS02760 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FZN31_RS02765 ENOG4105C2J ABC transporter FZN31_RS02770 ENOG4105CNN ABC, transporter FZN31_RS02775 ENOG4107UEK pfkb domain protein FZN31_RS02785 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FZN31_RS02790 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FZN31_RS02800 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family FZN31_RS02805 ENOG41062P1 Diguanylate cyclase phosphodiesterase FZN31_RS02810 ENOG4105DFF Rod shape-determining protein mreb FZN31_RS02815 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FZN31_RS02820 ENOG4105VQ7 Rod shape-determining protein MreD FZN31_RS02830 ENOG4105C03 ribonuclease FZN31_RS02835 ENOG4105QD6 exported protein FZN31_RS02840 ENOG4105D1U peptidase U62 modulator of DNA gyrase FZN31_RS02845 ENOG4105CR8 Transcriptional regulator FZN31_RS02865 ENOG4105UNR (Barnase) inhibitor FZN31_RS02870 ENOG4105RID UPF0379 protein yhcN FZN31_RS02885 ENOG4105C0H protease FZN31_RS02890 ENOG4105C0H protease FZN31_RS02895 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III FZN31_RS02900 ENOG4105D6Z AFG1 family ATPase FZN31_RS02910 ENOG4108UJD 30S ribosomal protein S9 FZN31_RS02920 ENOG4107MKT Stringent starvation protein a FZN31_RS02925 ENOG4105KB2 stringent starvation protein b FZN31_RS02930 ENOG4105CEE C4-dicarboxylate transporter FZN31_RS02960 ENOG4108R66 Conserved Protein FZN31_RS02965 ENOG4105DFS Conserved Protein FZN31_RS02970 ENOG4105BZ8 glutamate synthase FZN31_RS02975 ENOG4105CBC glutamate synthase FZN31_RS02980 ENOG4105N5T Radical SAM Protein FZN31_RS02985 ENOG4105BZU Histidine kinase FZN31_RS02990 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain FZN31_RS03000 ENOG4108NIH transferase activity, transferring phosphorus-containing groups FZN31_RS03005 ENOG41080Z8 PHOSPHOCARRIER protein FZN31_RS03015 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN FZN31_RS03020 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA FZN31_RS03025 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FZN31_RS03030 ENOG4108IUZ ABC transporter FZN31_RS03035 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FZN31_RS03040 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) FZN31_RS03050 ENOG4105C2X Arabinose 5-phosphate isomerase FZN31_RS03055 ENOG4105FEU K -dependent Na -Ca exchanger FZN31_RS03060 ENOG4105DHJ ABC, transporter FZN31_RS03065 ENOG4105CY3 ABC transporter, permease FZN31_RS03070 ENOG4107PE3 Mammalian cell entry related domain protein FZN31_RS03075 ENOG4105E3I toluene tolerance FZN31_RS03080 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane FZN31_RS03085 ENOG4105VFK BolA family FZN31_RS03095 ENOG4105HVQ Regulatory factor of maltose metabolism FZN31_RS03100 ENOG4105EAH synthase FZN31_RS03115 ENOG4105QYV Membrane FZN31_RS03125 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase FZN31_RS03130 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FZN31_RS03135 ENOG4105HBR Rna-binding protein FZN31_RS03140 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) FZN31_RS03145 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FZN31_RS03150 ENOG4105EEI dihydropteroate synthase FZN31_RS03170 ENOG4105DIJ Phosphoethanolamine transferase FZN31_RS03190 ENOG4105CHV Transcription elongation factor NusA FZN31_RS03205 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FZN31_RS03220 ENOG4105RT1 May be involved in cell division (By similarity) FZN31_RS03230 ENOG4105C1J atp-dependent rna helicase FZN31_RS03235 ENOG4105CIC tryptophan-specific transport protein FZN31_RS03240 ENOG4105DEN Luciferase family FZN31_RS03245 ENOG4106RZ4 Peptidase U32 FZN31_RS03250 ENOG4105CFP Peptidase U32 FZN31_RS03255 ENOG4105XPQ lipid carrier protein FZN31_RS03260 ENOG4108YYD acetyltransferase FZN31_RS03275 ENOG4107R7Y intracellular protease Pfpi family FZN31_RS03280 ENOG4105K4T epimerase FZN31_RS03285 ENOG4107S21 permease FZN31_RS03290 ENOG4105W4M Transport-associated protein FZN31_RS03305 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) FZN31_RS03310 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FZN31_RS03315 ENOG4106HBN Galactosamine-6-phosphate isomerase FZN31_RS03320 ENOG4105F3R pts system mannose fructose sorbose family iid FZN31_RS03325 ENOG4105ETZ PTS System FZN31_RS03330 ENOG4108UZY PTS System FZN31_RS03340 ENOG4105E70 isomerase FZN31_RS03345 ENOG4105CE4 GlcNAc 6-P deacetylase FZN31_RS03350 ENOG4108YTN IIa component FZN31_RS03355 ENOG4105F3R pts system mannose fructose sorbose family iid FZN31_RS03365 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB FZN31_RS03375 ENOG4105E98 transcriptional regulator DeoR family FZN31_RS03380 ENOG4105E98 transcriptional regulator DeoR family FZN31_RS03385 ENOG4105EZX Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity) FZN31_RS03400 ENOG4105F8D glycoside hydrolase family 4 FZN31_RS03405 ENOG4105CK1 PTS System FZN31_RS03410 ENOG4105VZJ PTS System FZN31_RS03415 ENOG4105CTX dehydratase FZN31_RS03420 ENOG4105DJB Major Facilitator Superfamily FZN31_RS03430 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FZN31_RS03435 ENOG4105BZW Glycerate kinase FZN31_RS03460 ENOG410811B TRANSCRIPTIONal FZN31_RS03465 ENOG4105C7B Threonine dehydratase FZN31_RS03470 ENOG4108MST Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity) FZN31_RS03475 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FZN31_RS03480 ENOG4105C6N Formate acetyltransferase FZN31_RS03485 ENOG4105KME endoribonuclease L-psp FZN31_RS03490 ENOG4105EJQ L-serine dehydratase FZN31_RS03495 ENOG4105C44 Serine transporter FZN31_RS03505 ENOG4106D80 Uncharacterized protein YhaL FZN31_RS03510 ENOG4108CNN domain protein FZN31_RS03515 ENOG4105CWB LysR family transcriptional Regulator FZN31_RS03520 ENOG4105KAF membrAne FZN31_RS03525 ENOG4105KAF membrAne FZN31_RS03530 ENOG4105CHF Glutathione S-transferase FZN31_RS03535 ENOG4108VBZ doxx family FZN31_RS03540 ENOG4105YJD FZN31_RS03545 ENOG41090KG Inner membrane protein YqjE FZN31_RS03550 ENOG4105NE1 Conserved Protein FZN31_RS03555 ENOG4105WAY exported protein FZN31_RS03560 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) FZN31_RS03565 ENOG4106W5V Membrane FZN31_RS03570 ENOG4107YCY Transcriptional regulator FZN31_RS03595 ENOG4105DPW Major facilitator superfamily MFS_1 FZN31_RS03605 ENOG4105CTX dehydratase FZN31_RS03610 ENOG4105P66 Membrane FZN31_RS03615 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FZN31_RS03620 ENOG4105DU1 integral membrane protein, terc FZN31_RS03625 ENOG4105EE0 oxidoreductase FZN31_RS03630 ENOG4108UB4 uncharacterized protein ygjQ FZN31_RS03635 ENOG4108VKG metal-dependent hydrolase FZN31_RS03640 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) FZN31_RS03645 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase FZN31_RS03650 ENOG4108Z3N Transcriptional regulator FZN31_RS03655 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FZN31_RS03660 ENOG4107WCA isomerase FZN31_RS03665 ENOG4107W6W Conserved Protein FZN31_RS03670 ENOG4105E5D amino acid FZN31_RS03675 ENOG4105FK9 beta-D-galactosidase beta subunit FZN31_RS03680 ENOG4105CNT hydrolase family 2 FZN31_RS03685 ENOG4105CQ4 Transcriptional regulator FZN31_RS03690 ENOG4108Y51 tRNA-binding protein FZN31_RS03700 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FZN31_RS03705 ENOG4105NTW Transcriptional regulator FZN31_RS03710 ENOG4105Q26 Siderophore-interacting protein FZN31_RS03725 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FZN31_RS03730 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FZN31_RS03735 ENOG4105VCC 30S ribosomal protein S21 FZN31_RS03745 ENOG4107QPK )-transporter FZN31_RS03750 ENOG4107GFK fumarate FZN31_RS03755 ENOG4106DSS Tartrate dehydratase subunit alpha FZN31_RS03760 ENOG4105EJC lysr family transcriptional regulator FZN31_RS03770 ENOG4107ZVW dihydroneopterin aldolase FZN31_RS03785 ENOG4106MWK domain protein FZN31_RS03790 ENOG4105D7V transposase FZN31_RS03800 ENOG4105I7R Adenylate cyclase FZN31_RS03820 ENOG4107S78 Band 7 protein FZN31_RS03825 ENOG4105PV3 Inner membrane protein yqiJ FZN31_RS03835 ENOG4105W0Z cytoplasmic protein FZN31_RS03855 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FZN31_RS03860 ENOG4106032 Glutathionylspermidine synthase FZN31_RS03870 ENOG4105DFG type I secretion outer membrane protein FZN31_RS03875 ENOG41087AY ADP-Ribose pyrophosphatase FZN31_RS03880 ENOG4108SX3 cytoplasmic protein FZN31_RS03885 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FZN31_RS03890 ENOG4105IPS esterase FZN31_RS03895 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FZN31_RS03905 ENOG4105E0A ABC, transporter FZN31_RS03910 ENOG4105DQ5 transport system permease protein FZN31_RS03915 ENOG4105EHG Permease protein FZN31_RS03930 ENOG4105VRH Antibiotic biosynthesis monooxygenase FZN31_RS03935 ENOG4105NF4 modulator of drug activity FZN31_RS03940 ENOG4107DEU Inner membrane protein YgiZ FZN31_RS03945 ENOG4105DHQ Histidine kinase FZN31_RS03950 ENOG4105XJC Two component transcriptional regulator (Winged helix family FZN31_RS03955 ENOG4105H4F exported protein FZN31_RS03960 ENOG4105F4I Transcriptional regulator FZN31_RS03965 ENOG4108J59 Extracellular solute-binding protein, family 5 FZN31_RS03970 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FZN31_RS03975 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase FZN31_RS03980 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) FZN31_RS03985 ENOG4105CCT upf0313 protein FZN31_RS04000 ENOG4105ZKC Conserved Protein FZN31_RS04005 ENOG4105CV8 reductase FZN31_RS04010 ENOG4108I6A alcohol dehydrogenase FZN31_RS04015 ENOG4105CF7 AraC family transcriptional regulator FZN31_RS04020 ENOG4108K81 inner membrane protein YghB FZN31_RS04025 ENOG4105C28 cystathionine FZN31_RS04030 ENOG4105CWK Biopolymer transport protein, ExbB FZN31_RS04035 ENOG4108ZZF transport protein (ExbD) FZN31_RS04040 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FZN31_RS04050 ENOG4105CPC Aldo Keto reductase FZN31_RS04060 ENOG410900S Protein of unknown function (DUF2623) FZN31_RS04065 ENOG4105E3S small subunit FZN31_RS04070 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FZN31_RS04075 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit FZN31_RS04080 ENOG4105DPX Hydrogenase, large subunit FZN31_RS04085 ENOG4108USZ hydrogenase FZN31_RS04090 ENOG4108WGS hydrogenase 2-specific chaperone FZN31_RS04095 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FZN31_RS04100 ENOG41082MF Hydrogenase assembly chaperone hypC hupF FZN31_RS04105 ENOG4105CYM Glutathione S-transferase FZN31_RS04110 ENOG4106032 Glutathionylspermidine synthase FZN31_RS04115 ENOG4105CJ3 phosphate transporter FZN31_RS04120 ENOG4108GH0 ATP-binding protein yghT FZN31_RS04125 ENOG4108NDC ATP-binding protein yghS FZN31_RS04130 ENOG4106FPV ATP-binding protein YghR FZN31_RS04135 ENOG4108S55 polysaccharide biosynthesis protein FZN31_RS04145 ENOG4108UUE Transcriptional regulator FZN31_RS04150 ENOG4108M8S permease YjgP YjgQ family protein FZN31_RS04165 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FZN31_RS04175 ENOG4107RCI amp-dependent synthetase and ligase FZN31_RS04185 ENOG4108KWP DNA-binding transcriptional regulator GlcC FZN31_RS04190 ENOG4105CQB FAD linked oxidase domain protein FZN31_RS04195 ENOG4105EU8 FAD linked oxidase domain protein FZN31_RS04200 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FZN31_RS04205 ENOG4108ZJF Glcg protein FZN31_RS04210 ENOG4107QP3 malate synthase g FZN31_RS04215 ENOG4105DAA L-lactate FZN31_RS04220 ENOG4105F88 accessory colonization factor AcfD FZN31_RS04225 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) FZN31_RS04230 ENOG410765S (LipO)protein FZN31_RS04245 ENOG4107QHF type ii secretion system protein e FZN31_RS04250 ENOG4105D7Q type ii secretion system FZN31_RS04255 ENOG4108VAU general secretion pathway protein G FZN31_RS04265 ENOG4105X5Z General secretion pathway protein I FZN31_RS04285 ENOG4105U1E general secretion pathway protein M FZN31_RS04295 ENOG4108UQV Membrane FZN31_RS04300 ENOG4105CXN decarboxylase FZN31_RS04305 ENOG4105EAA nucleoside FZN31_RS04320 ENOG4105CEN a g-specific adenine glycosylase FZN31_RS04330 ENOG41090ED Protein with unknown function (DUF469) FZN31_RS04340 ENOG4105K33 Periplasmic Protein FZN31_RS04345 ENOG4105HDK L-asparaginase FZN31_RS04350 ENOG4106MH3 alpha helix chain FZN31_RS04355 ENOG4105CSA Coproporphyrinogen iii oxidase FZN31_RS04360 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FZN31_RS04370 ENOG4108VIA integral membrane protein FZN31_RS04375 ENOG4105DFA alanine racemase domain protein FZN31_RS04380 ENOG4105CZX twitching motility protein FZN31_RS04395 ENOG4105D7Z glutathione synthase FZN31_RS04400 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FZN31_RS04405 ENOG4105RWS endonuclease I FZN31_RS04415 ENOG4107QNK )-transporter FZN31_RS04435 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) FZN31_RS04460 ENOG4108EQA pts system FZN31_RS04465 ENOG4105ETZ PTS System FZN31_RS04470 ENOG4105F3R pts system mannose fructose sorbose family iid FZN31_RS04485 ENOG4108K0D peptidase, M48 FZN31_RS04490 ENOG4105CV1 Transketolase (EC 2.2.1.1) FZN31_RS04495 ENOG4105EPW hflc protein FZN31_RS04500 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia FZN31_RS04505 ENOG4105CTS PTS system mannitol-specific FZN31_RS04510 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FZN31_RS04515 ENOG4108Q8A Fructose-1,6-bisphosphatase FZN31_RS04520 ENOG4108R4K DNA-binding, transcriptional regulator FZN31_RS04525 ENOG4107Z1W Fructose transport system kinase FZN31_RS04530 ENOG4108JJB ABC transporter FZN31_RS04565 ENOG4105D2N Aldolase FZN31_RS04570 ENOG4105D64 Mechanosensitive ion channel FZN31_RS04575 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FZN31_RS04580 ENOG4105MPN Membrane FZN31_RS04585 ENOG4105DEQ transcriptional regulator FZN31_RS04590 ENOG4105CYC Transferase FZN31_RS04595 ENOG4108M7F enoyl-CoA hydratase isomerase FZN31_RS04600 ENOG4105DJT lAO AO transport system ATPase FZN31_RS04605 ENOG4105D5P Methylmalonyl-coA mutase FZN31_RS04625 ENOG4108JQ1 Dehydrogenase FZN31_RS04635 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FZN31_RS04655 ENOG4107RAQ aminopeptidase FZN31_RS04660 ENOG4105D0A hydroxylase FZN31_RS04665 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FZN31_RS04690 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FZN31_RS04695 ENOG4105CS2 ec 3.2.1.21 FZN31_RS04700 ENOG4105N5Z UPF0267 protein FZN31_RS04705 ENOG4108UT2 hemolysin iii FZN31_RS04715 ENOG4105Y75 tpr repeat protein FZN31_RS04720 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB FZN31_RS04725 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) FZN31_RS04730 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FZN31_RS04735 ENOG4105T95 Thiol disulfide interChange protein FZN31_RS04740 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FZN31_RS04750 ENOG4105CRK lysyL-tRNA synthetase FZN31_RS04765 ENOG4105C2W permease FZN31_RS04770 ENOG4105BZ8 glutamate synthase FZN31_RS04775 ENOG4108R8B oxidoreductase Fe-S subunit FZN31_RS04780 ENOG4105C7N Xanthine uracil vitamin C permease FZN31_RS04785 ENOG4107QUY Guanine deaminase FZN31_RS04790 ENOG4105C2W permease FZN31_RS04795 ENOG4105C7W Xanthine dehydrogenase FZN31_RS04800 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase FZN31_RS04805 ENOG4107UUR Chlorohydrolase aminohydrolase FZN31_RS04810 ENOG4105BZ8 glutamate synthase FZN31_RS04815 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase FZN31_RS04820 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC FZN31_RS04825 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FZN31_RS04830 ENOG4105C5B carbamate kinase FZN31_RS04840 ENOG4107S4Y M20 DapE family protein YgeY FZN31_RS04845 ENOG4107RCH Diaminopropionate ammonia-lyase FZN31_RS04850 ENOG4105IW6 Carbamoyltransferase FZN31_RS04855 ENOG4108JUB Transcriptional regulator FZN31_RS04860 ENOG4108UTP (2Fe-2S)-binding domain protein FZN31_RS04865 ENOG4108HR6 Dehydrogenase FZN31_RS04870 ENOG4105C7W Xanthine dehydrogenase FZN31_RS04875 ENOG4108K5P (LipO)protein FZN31_RS04885 ENOG4108T88 FZN31_RS04895 ENOG41090HZ type iii secretion FZN31_RS04900 ENOG4105K44 type iii secretion FZN31_RS04905 ENOG4108N8R Invasion protein FZN31_RS04910 ENOG4108HR8 type iii secretion FZN31_RS04915 ENOG4108JIR Flagellum-specific ATP synthase FZN31_RS04930 ENOG4105T85 surface presentation of antigens protein FZN31_RS04935 ENOG41075IY surface presentation of antigens protein SpaP FZN31_RS04945 ENOG4108TN6 type iii secretion FZN31_RS04950 ENOG4108M6W surface presentation of antigens protein SpaS FZN31_RS04965 ENOG4108RC9 Type III secretion system protein FZN31_RS04970 ENOG4105Y7Q type iii secretion FZN31_RS04975 ENOG4106BTR FZN31_RS04980 ENOG4108RBT type iii secretion FZN31_RS05000 ENOG4105K5T PilT protein FZN31_RS05010 ENOG4108YAB Invasion protein FZN31_RS05035 ENOG4105FV3 FZN31_RS05040 ENOG4108TC1 Transcriptional regulator FZN31_RS05045 ENOG4105ISV protein with bipartite regulator domain FZN31_RS05050 ENOG4108MHD transport protein FZN31_RS05055 ENOG4105CHU acetyl-coa acetyltransferase FZN31_RS05065 ENOG4105CHR reductase FZN31_RS05070 ENOG4107QNK )-transporter FZN31_RS05080 ENOG4105RQF LysR family Transcriptional regulator FZN31_RS05085 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FZN31_RS05090 ENOG41060NJ transcriptional regulator FZN31_RS05110 ENOG4105CPC Aldo Keto reductase FZN31_RS05115 ENOG4105SUV lipoprotein YgdR FZN31_RS05120 ENOG4105EE5 Membrane protein terC FZN31_RS05135 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FZN31_RS05150 ENOG4105IPU prepilin peptidase dependent protein A FZN31_RS05155 ENOG4105JCS prepilin peptidase dependent protein FZN31_RS05160 ENOG4105SEN Protein of unknown function (DUF2509) FZN31_RS05165 ENOG4105RVB Prepilin peptidase dependent protein c FZN31_RS05170 ENOG4105DSY exodeoxyribonuclease V, gamma FZN31_RS05175 ENOG4107QXK peptidase FZN31_RS05180 ENOG4107QKA exodeoxyribonuclease V beta FZN31_RS05185 ENOG4107QYX exodeoxyribonuclease v alpha FZN31_RS05190 ENOG4107QZM n-acetylglutamate synthase FZN31_RS05195 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FZN31_RS05200 ENOG4105CID antiterminator FZN31_RS05205 ENOG4105CI1 PTS System FZN31_RS05210 ENOG4105C87 Aminotransferase class I and II FZN31_RS05215 ENOG4105C2X Arabinose 5-phosphate isomerase FZN31_RS05240 ENOG4105CA3 membrane-bound lytic murein transglycosylase FZN31_RS05245 ENOG4105CUZ uba thif-type nad fad binding protein FZN31_RS05250 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) FZN31_RS05255 ENOG4105C9B Cysteine desulfurase FZN31_RS05260 ENOG4105M5B (LipO)protein FZN31_RS05265 ENOG4105ETT transcriptional Regulator, LysR family FZN31_RS05270 ENOG4105M08 Membrane FZN31_RS05280 ENOG4107EDW L-fucose operon activator FZN31_RS05290 ENOG4105CMG Carbohydrate kinase FZN31_RS05300 ENOG4105C2J ABC transporter FZN31_RS05305 ENOG4105CNN ABC, transporter FZN31_RS05315 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FZN31_RS05325 ENOG4107W7X Aldolase FZN31_RS05330 ENOG4105C0A alcohol dehydrogenase FZN31_RS05340 ENOG4105EJQ L-serine dehydratase FZN31_RS05345 ENOG4105C44 Serine transporter FZN31_RS05350 ENOG4105EWT decarboxylase family FZN31_RS05365 ENOG4105WP7 tRNA pseudouridine synthase C FZN31_RS05370 ENOG4105DR9 pseudouridine synthase FZN31_RS05375 ENOG4105QDK Flavodoxin FZN31_RS05380 ENOG4105DJB Major Facilitator Superfamily FZN31_RS05385 ENOG4105EQX glucarate dehydratase FZN31_RS05390 ENOG4105EQX glucarate dehydratase FZN31_RS05395 ENOG4105BZU Histidine kinase FZN31_RS05405 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FZN31_RS05410 ENOG4106A2Z transcriptional regulator antitoxin, MazE FZN31_RS05415 ENOG4105MZG transcriptional modulator of maze toxin, mazf FZN31_RS05420 ENOG4105DXN mazG family FZN31_RS05435 ENOG4105HA9 of methanol dehydrogenase type FZN31_RS05445 ENOG4105HA9 of methanol dehydrogenase type FZN31_RS05455 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FZN31_RS05460 ENOG4108CWB sugar kinase ygcE FZN31_RS05465 ENOG4108ITV Inner membrane protein yqcE FZN31_RS05470 ENOG4105CHR reductase FZN31_RS05475 ENOG4107R3A FAD linked oxidase domain protein FZN31_RS05480 ENOG4105C54 Major Facilitator superfamily FZN31_RS05485 ENOG4106IKH Electron transfer flavoprotein FZN31_RS05490 ENOG4105YBM electron transfer flavoprotein subunit ygcQ FZN31_RS05495 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FZN31_RS05500 ENOG4105WQV ferredoxin-like protein FZN31_RS05505 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FZN31_RS05510 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FZN31_RS05530 ENOG4107635 Hok Gef family protein FZN31_RS05535 ENOG4105DTT CRISPR-associated helicase, cas3 FZN31_RS05540 ENOG4105CYR Crispr-associated protein, cse1 family FZN31_RS05550 ENOG41060M0 Crispr-associated protein, cse4 family FZN31_RS05555 ENOG4108VWQ crispr-associated protein FZN31_RS05565 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) FZN31_RS05570 ENOG4105PWE CRISPR-associated protein cas2 FZN31_RS05575 ENOG4108MXK alkaline phosphatase isozyme conversion FZN31_RS05595 ENOG4105N0Z inner membrane protein ygbE FZN31_RS05615 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) FZN31_RS05630 ENOG4108K5P (LipO)protein FZN31_RS05645 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FZN31_RS05650 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FZN31_RS05655 ENOG4105KZM cytoplasmic protein FZN31_RS05660 ENOG4105C6Z Gluconate FZN31_RS05665 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FZN31_RS05670 ENOG4105FB2 class II Aldolase FZN31_RS05675 ENOG4105G63 Type III effector Hrp-dependent FZN31_RS05680 ENOG4105ZXK Dehydrogenase FZN31_RS05685 ENOG4105MVE transcriptional regulator FZN31_RS05690 ENOG4105MEW serine threonine protein phosphatase FZN31_RS05700 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) FZN31_RS05710 ENOG4105VXR cytoplasmic protein FZN31_RS05715 ENOG4108JUA Transcriptional regulator FZN31_RS05720 ENOG4105C45 hydrogenase expression formation protein (HypE) FZN31_RS05725 ENOG4105CQS hydrogenase expression formation protein HypD FZN31_RS05730 ENOG41083WG hydrogenase assembly chaperone FZN31_RS05735 ENOG4107RSS Hydrogenase accessory protein HypB FZN31_RS05740 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) FZN31_RS05745 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA FZN31_RS05750 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FZN31_RS05755 ENOG4107R30 NADH dehydrogenase FZN31_RS05760 ENOG4107TDF Formate hydrogenlyase subunit 4 FZN31_RS05765 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FZN31_RS05770 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit FZN31_RS05775 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FZN31_RS05780 ENOG4105I6X formate hydrogenlyase maturation FZN31_RS05785 ENOG4108MG9 hydrogenase 3 maturation protease FZN31_RS05795 ENOG4105RVE Uncharacterized protein conserved in bacteria (DUF2136) FZN31_RS05800 ENOG4108Z3N Transcriptional regulator FZN31_RS05805 ENOG4105CS2 ec 3.2.1.21 FZN31_RS05810 ENOG4105C5Y PTS System FZN31_RS05815 ENOG4105DDV Transcriptional regulator (LacI family FZN31_RS05820 ENOG4108RC0 Electron transport protein FZN31_RS05825 ENOG4105C8H hydrogenase maturation protein Hypf FZN31_RS05850 ENOG410804X Transcriptional regulator FZN31_RS05855 ENOG4105J92 DNA-binding transcriptional activator GutM FZN31_RS05860 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase FZN31_RS05865 ENOG4105VI0 Pts system, glucitol sorbitol-specific FZN31_RS05870 ENOG4105DZY Pts system, glucitol sorbitol-specific FZN31_RS05875 ENOG410787A Pts system, glucitol sorbitol-specific FZN31_RS05880 ENOG4105CVE Lytic murein transglycosylase FZN31_RS05890 ENOG4107TH8 cina domain protein FZN31_RS05910 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FZN31_RS05940 ENOG4107VXZ Hydrolase FZN31_RS05945 ENOG4105W39 Membrane FZN31_RS05970 ENOG4105C0R drug resistance transporter emrb qaca subfamily FZN31_RS05975 ENOG4105CW7 secretion protein, HlyD family FZN31_RS05980 ENOG4105NTK Transcriptional repressor Mpra FZN31_RS05990 ENOG4105ZED uncharacterized protein ygaH FZN31_RS05995 ENOG4108UMN azlc family FZN31_RS06005 ENOG4105GIJ Glycine betaine FZN31_RS06010 ENOG4108HQS Glycine betaine FZN31_RS06015 ENOG4108IJ7 Glycine betaine FZN31_RS06020 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FZN31_RS06025 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FZN31_RS06030 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FZN31_RS06035 ENOG4105WAZ (Glutaredoxin-like protein) NrdH FZN31_RS06040 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FZN31_RS06050 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) FZN31_RS06055 ENOG4108WMJ Protein of unknown function (DUF2002) FZN31_RS06060 ENOG4108RNS Exports L-alanine (By similarity) FZN31_RS06065 ENOG4108X73 DNA- binding protein FZN31_RS06070 ENOG4108V62 Rhodanese domain protein FZN31_RS06075 ENOG41080HT Transcriptional regulator, arsr family FZN31_RS06080 ENOG4105VPI YqaE family transport protein FZN31_RS06085 ENOG4109066 lysm domain bon superfamily protein FZN31_RS06090 ENOG4108PVQ transcriptional regulator FZN31_RS06095 ENOG4105C85 amino acid FZN31_RS06100 ENOG4108JPW Aminotransferase FZN31_RS06105 ENOG4105C26 Dehydrogenase FZN31_RS06110 ENOG4105D5U fad dependent oxidoreductase FZN31_RS06115 ENOG4105EK3 May be involved in the control of utilization of gamma- aminobutyric acid (By similarity) FZN31_RS06120 ENOG4105E54 alpha-amylase FZN31_RS06135 ENOG4108C33 Resolvase FZN31_RS06145 ENOG4108MGN ATP-binding component of a transport system FZN31_RS06255 ENOG4105DFP Integrase FZN31_RS06270 ENOG4108Z1B Cyclase dehydrase FZN31_RS06280 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FZN31_RS06285 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FZN31_RS06300 ENOG4108JU6 CBS domain protein FZN31_RS06305 ENOG4106KVJ cytochrome C assembly protein FZN31_RS06310 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FZN31_RS06335 ENOG41090EK ompa motb domain protein FZN31_RS06340 ENOG4108KHX Diguanylate cyclase FZN31_RS06345 ENOG4108WS1 FZN31_RS06350 ENOG4105QP9 Protein of unknown function (DUF2799) FZN31_RS06355 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FZN31_RS06360 ENOG4105EHE chorismate mutase- prephenate dehydrogenase FZN31_RS06365 ENOG4105CQC Prephenate dehydratase FZN31_RS06375 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FZN31_RS06475 ENOG4105ED4 portal protein FZN31_RS06605 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FZN31_RS06610 ENOG4105CEC DNA methylase N-4 N-6 FZN31_RS06615 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA FZN31_RS06625 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FZN31_RS06630 ENOG4105C34 Pseudouridine synthase FZN31_RS06635 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FZN31_RS06640 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FZN31_RS06665 ENOG4105CSH Transporter FZN31_RS06670 ENOG4105T42 (LipO)protein FZN31_RS06675 ENOG4105JIM Phosphatidylserine synthase FZN31_RS06680 ENOG4105CD5 CoA-binding domain protein FZN31_RS06685 ENOG4106IUH DTW domain containing protein FZN31_RS06690 ENOG4105K63 Thioredoxin FZN31_RS06695 ENOG4105EIB trna rrna methyltransferase FZN31_RS06715 ENOG41090KR LysR family transcriptional Regulator FZN31_RS06720 ENOG4105C1J atp-dependent rna helicase FZN31_RS06730 ENOG4108IYU L-aspartate oxidase FZN31_RS06740 ENOG4105EMN RNA polymerase sigma factor FZN31_RS06745 ENOG41069PW sigma-e factor negative regulatory protein FZN31_RS06750 ENOG4105VQK sigma E regulatory protein, MucB RseB FZN31_RS06755 ENOG4105WMJ Positive regulator of sigma E, RseC MucC FZN31_RS06765 ENOG4105C3F Signal peptidase i FZN31_RS06785 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FZN31_RS06800 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FZN31_RS06805 ENOG4106G6Q Transcriptional regulator FZN31_RS06810 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB FZN31_RS06815 ENOG4108Z6B deaminase FZN31_RS06825 ENOG4108ETH Formylglycinamide ribotide synthetase FZN31_RS06830 ENOG4107WP9 Histidine kinase FZN31_RS06835 ENOG4108SKK alpha helix protein FZN31_RS06840 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FZN31_RS06845 ENOG4108YZA Nitrogen regulatory protein pii FZN31_RS06850 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FZN31_RS06860 ENOG4108NZE NAGC-like transcriptional regulator FZN31_RS06865 ENOG4107HQ7 repeat protein FZN31_RS06870 ENOG4105FCA ABC transporter periplasmic-binding protein YphF FZN31_RS06875 ENOG4108F37 ATP-binding component of a transport system FZN31_RS06880 ENOG4105CNN ABC, transporter FZN31_RS06885 ENOG4105CPQ Dehydrogenase FZN31_RS06890 ENOG4108ZKT aldose 1-epimerase FZN31_RS06895 ENOG4108SB3 DoxX Family FZN31_RS06920 ENOG4105FUY alpha subunit FZN31_RS06925 ENOG4108W5M transcriptional regulator FZN31_RS06930 ENOG4105D8G Major Facilitator superfamily FZN31_RS06935 ENOG4108MN2 Stationary phase inducible protein CsiE FZN31_RS06940 ENOG4107XM9 (LipO)protein FZN31_RS06950 ENOG4105CVS RNA methyltransferase TrmH family, group 1 FZN31_RS06965 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FZN31_RS06985 ENOG4108ZIT Ferredoxin, 2FE-2S FZN31_RS06990 ENOG4105WVQ Fe-S assembly protein IscX FZN31_RS07000 ENOG4105YYA enhanced serine sensitivity protein SseB FZN31_RS07005 ENOG4105KHC sulfurtransferase FZN31_RS07010 ENOG4105DN3 alpha-2-macroglobulin domain protein FZN31_RS07015 ENOG4108JQB penicillin-binding protein 1C FZN31_RS07045 ENOG4105N21 Membrane FZN31_RS07060 ENOG4105VPD cellular component movement FZN31_RS07085 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FZN31_RS07110 ENOG41066DY Membrane FZN31_RS07115 ENOG4108ZMA Outer membrane lipoprotein FZN31_RS07120 ENOG41062G3 Protein of unknown function (DUF2633) FZN31_RS07130 ENOG4105BZU Histidine kinase FZN31_RS07135 ENOG4105C9X ppx gppa phosphatase FZN31_RS07140 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FZN31_RS07145 ENOG4108V3E phosphoribosylglycinamide formyltransferase FZN31_RS07160 ENOG4105C2W permease FZN31_RS07170 ENOG4105K89 arsenate reductase FZN31_RS07175 ENOG4105ERG peptidase m48, ste24p FZN31_RS07180 ENOG4105C02 permease FZN31_RS07185 ENOG4105TMB Formate nitrite transporter FZN31_RS07190 ENOG4108JUA Transcriptional regulator FZN31_RS07195 ENOG4105I6X formate hydrogenlyase maturation FZN31_RS07200 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit FZN31_RS07210 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FZN31_RS07215 ENOG4108JPZ Monovalent cation H antiporter subunit D FZN31_RS07220 ENOG4107WQX hydrogenase 4 membrane subunit FZN31_RS07225 ENOG4105D65 subunit l FZN31_RS07230 ENOG4107TDF Formate hydrogenlyase subunit 4 FZN31_RS07235 ENOG4108JPZ Monovalent cation H antiporter subunit D FZN31_RS07240 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) FZN31_RS07245 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FZN31_RS07250 ENOG4105RH4 Glycine cleavage system transcriptional repressor FZN31_RS07260 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FZN31_RS07270 ENOG4105CGZ zinc metallopeptidase FZN31_RS07275 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) FZN31_RS07280 ENOG4106KED esterase YpfH FZN31_RS07295 ENOG4105KUZ arsenate reductase FZN31_RS07305 ENOG4105BZS acriflavin resistance protein FZN31_RS07310 ENOG4105BZU Histidine kinase FZN31_RS07315 ENOG4105BZ8 glutamate synthase FZN31_RS07325 ENOG4108PVD exported protein FZN31_RS07330 ENOG4105CV1 Transketolase (EC 2.2.1.1) FZN31_RS07335 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FZN31_RS07340 ENOG4105C6K Malic enzyme FZN31_RS07345 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place FZN31_RS07350 ENOG4106S4J ethanolamine utilization protein EutP FZN31_RS07355 ENOG4105NDK ethanolamine utilization protein FZN31_RS07360 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase FZN31_RS07365 ENOG4107WUY phosphate acetyltransferase FZN31_RS07370 ENOG4105KNY Microcompartments protein FZN31_RS07375 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml FZN31_RS07380 ENOG4108EKI Dehydrogenase FZN31_RS07385 ENOG4107RWI ethanolamine utilization protein eutJ FZN31_RS07390 ENOG4105C0A alcohol dehydrogenase FZN31_RS07395 ENOG4105ENY Ethanolamine utilization protein eutH FZN31_RS07400 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase FZN31_RS07405 ENOG4105CPD ethanolamine ammonia-lyase FZN31_RS07415 ENOG4106D67 ethanolamine utilization protein FZN31_RS07420 ENOG4108X49 Ethanolamine utilization protein EutK FZN31_RS07425 ENOG4108K3Z AraC family transcriptional regulator FZN31_RS07445 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase FZN31_RS07450 ENOG4108R6G acetyltransferase FZN31_RS07455 ENOG4105QZU Inner membrane protein YfeZ FZN31_RS07460 ENOG4105E7K (LipO)protein FZN31_RS07465 ENOG4105EZR dyp-type peroxidase family protein FZN31_RS07470 ENOG4107QK9 Beta-lactamase FZN31_RS07475 ENOG4105C5Y PTS System FZN31_RS07480 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FZN31_RS07490 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FZN31_RS07495 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein FZN31_RS07500 ENOG4108I5D sulfate abc transporter FZN31_RS07505 ENOG4105ECW sulfate abc transporter FZN31_RS07510 ENOG4108IJ6 ABC transporter FZN31_RS07515 ENOG4105C6T cysteine synthase FZN31_RS07520 ENOG4105M0Y FZN31_RS07530 ENOG4105C5Y PTS System FZN31_RS07535 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FZN31_RS07540 ENOG4105KZ7 phosphocarrier protein hpr FZN31_RS07545 ENOG4105C6T cysteine synthase FZN31_RS07555 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) FZN31_RS07565 ENOG4105VRT cytoplasmic protein FZN31_RS07570 ENOG4105DHU Bile acid FZN31_RS07575 ENOG4108NFH Sugar hydrolase FZN31_RS07580 ENOG4105EAA nucleoside FZN31_RS07590 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) FZN31_RS07595 ENOG4105EAA nucleoside FZN31_RS07600 ENOG4105CN8 Transcriptional regulator FZN31_RS07625 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FZN31_RS07630 ENOG4105GXM Putative transcription regulator (DUF1323) FZN31_RS07635 ENOG4105HZG regulatoR FZN31_RS07650 ENOG4108KMM Diguanylate cyclase FZN31_RS07655 ENOG4105D9N nucleoside FZN31_RS07665 ENOG4109076 Conserved Protein FZN31_RS07680 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) FZN31_RS07685 ENOG410863U PTS System FZN31_RS07690 ENOG4105DC7 peptidase M24 FZN31_RS07695 ENOG4105CN9 Peptidase m42 family protein FZN31_RS07700 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FZN31_RS07705 ENOG4108CIP transcriptional regulator FZN31_RS07710 ENOG4105DY9 regulatoR FZN31_RS07720 ENOG4105CHM Aminotransferase FZN31_RS07730 ENOG4105D1S lipid A biosynthesis FZN31_RS07735 ENOG4105W9M Membrane FZN31_RS07745 ENOG4108V08 YfdX protein FZN31_RS07755 ENOG4105CFN oxalyl-CoA decarboxylase FZN31_RS07760 ENOG4108N2Y auxin Efflux FZN31_RS07765 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FZN31_RS07770 ENOG4105BZU Histidine kinase FZN31_RS07775 ENOG4108WQH regulatoR FZN31_RS07780 ENOG4105CW7 secretion protein, HlyD family FZN31_RS07785 ENOG4105C0R drug resistance transporter emrb qaca subfamily FZN31_RS07790 ENOG4105BZC d-serine deaminase FZN31_RS07800 ENOG4106NDP Transcriptional regulator FZN31_RS07805 ENOG4108HKT sucrose-6-phosphate hydrolase FZN31_RS07810 ENOG4105D7K pfkb domain protein FZN31_RS07815 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FZN31_RS07820 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision FZN31_RS07840 ENOG4105HEI LysR family (Transcriptional regulator FZN31_RS07860 ENOG4105S64 Formate nitrite transporter FZN31_RS07865 ENOG410903C (LipO)protein FZN31_RS07875 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation FZN31_RS07880 ENOG4105KZW UPF0381 protein FZN31_RS07890 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FZN31_RS07895 ENOG4108BY2 phosphohistidine phosphatase FZN31_RS07905 ENOG4106PG1 outer membrane usher protein FZN31_RS07910 ENOG4108FZ9 Chaperone FZN31_RS07915 ENOG4105NEV Fimbrial FZN31_RS07920 ENOG4105UGQ Fimbrial FZN31_RS07925 ENOG4105US4 fimbrial-like protein yfcP FZN31_RS07950 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) FZN31_RS07955 ENOG4105EJ9 Membrane FZN31_RS07960 ENOG4108BPE -transporting atpase FZN31_RS07965 ENOG4105MH2 YfcL protein FZN31_RS07970 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FZN31_RS07975 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FZN31_RS07980 ENOG4105F9N Major Facilitator Superfamily FZN31_RS07985 ENOG4106WZ1 flagella biosynthesis regulator FZN31_RS07990 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) FZN31_RS07995 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FZN31_RS08005 ENOG4105DQR SNARE associated Golgi FZN31_RS08015 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FZN31_RS08020 ENOG4108S3P Sporulation domain protein FZN31_RS08025 ENOG4105E96 Colicin v production protein FZN31_RS08030 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FZN31_RS08035 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FZN31_RS08040 ENOG4105E89 ABC transporter FZN31_RS08045 ENOG4105E89 ABC transporter FZN31_RS08050 ENOG4105DSP amino acid AbC transporter FZN31_RS08055 ENOG4106YG3 ABC transporter FZN31_RS08060 ENOG4108JEH abc transporter atp-binding protein FZN31_RS08065 ENOG4105DNE Transposase FZN31_RS08070 ENOG4105ECP epimerase FZN31_RS08075 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase FZN31_RS08080 ENOG4105CYM Glutathione S-transferase FZN31_RS08085 ENOG4108SHQ Glutathione S-transferase FZN31_RS08090 ENOG4108RE9 Phosphodiesterase FZN31_RS08095 ENOG4105PTV Nudix Hydrolase FZN31_RS08100 ENOG4105CSX c4-dicarboxylate anaerobic carrier FZN31_RS08105 ENOG4105C6K Malic enzyme FZN31_RS08110 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FZN31_RS08125 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 FZN31_RS08130 ENOG4107QWE )-transporter FZN31_RS08140 ENOG4105CHM Aminotransferase FZN31_RS08145 ENOG4107NQ8 LysR family Transcriptional regulator FZN31_RS08165 ENOG4105GKE subunit e FZN31_RS08170 ENOG4107QIZ NADH dehydrogenase FZN31_RS08175 ENOG4108IEH NADH dehydrogenase subunit g FZN31_RS08185 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FZN31_RS08190 ENOG4107UFS subunit j FZN31_RS08195 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FZN31_RS08200 ENOG4105D65 subunit l FZN31_RS08205 ENOG4105C8S subunit m FZN31_RS08215 ENOG4105GDX Domain of unknown function (DUF1877) FZN31_RS08220 ENOG4107VAM peptidase, m28 FZN31_RS08225 ENOG4105CP2 von willebrand factor, type a FZN31_RS08230 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is FZN31_RS08240 ENOG4107YB6 acetyltransferase, (GNAT) family FZN31_RS08245 ENOG4105TNS Conserved Protein FZN31_RS08250 ENOG4105E4F Isochorismate synthase FZN31_RS08265 ENOG4108IPT Naphthoate synthase FZN31_RS08275 ENOG4105CEY Amp-dependent synthetase and ligase FZN31_RS08280 ENOG4106GZG polymyxin resistance protein B FZN31_RS08330 ENOG4108UII YfaZ family FZN31_RS08340 ENOG4107258 Transcriptional regulator FZN31_RS08350 ENOG4105CSP Major Facilitator Superfamily FZN31_RS08360 ENOG4105DNE Transposase FZN31_RS08365 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FZN31_RS08375 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A FZN31_RS08380 ENOG4105CXY transporter FZN31_RS08385 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FZN31_RS08400 ENOG4105FQR PH-inducible protein involved in stress response FZN31_RS08405 ENOG4105XPH Ferredoxin FZN31_RS08410 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FZN31_RS08415 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FZN31_RS08420 ENOG4107GHC outer membrane autotransporter FZN31_RS08430 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FZN31_RS08435 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) FZN31_RS08440 ENOG4108QJJ Protein of unknown function (DUF1175) FZN31_RS08445 ENOG4107S52 alpha-2-macroglobulin domain protein FZN31_RS08450 ENOG41081SK signal peptide protein FZN31_RS08455 ENOG4105EDV vault protein FZN31_RS08460 ENOG4105CHU acetyl-coa acetyltransferase FZN31_RS08465 ENOG4105CRW Short chain fatty acid transporter FZN31_RS08470 ENOG4107QNJ CoA-transferase subunit B FZN31_RS08475 ENOG4107QP7 CoA-transferase subunit A FZN31_RS08480 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FZN31_RS08485 ENOG4105BZU Histidine kinase FZN31_RS08490 ENOG4105BZU Histidine kinase FZN31_RS08495 ENOG41068CG regulatoR FZN31_RS08500 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC FZN31_RS08505 ENOG4105FCK Membrane FZN31_RS08510 ENOG4105CJ2 (LipO)protein FZN31_RS08515 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FZN31_RS08520 ENOG4105CF1 Alkylated DNA repair protein FZN31_RS08525 ENOG4105IBP Cyclic peptide transporter FZN31_RS08540 ENOG4108ZNS ferredoxin-type protein NapF FZN31_RS08545 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase FZN31_RS08555 ENOG4108BGM Quinol dehydrogenase periplasmic component FZN31_RS08560 ENOG4105GXZ Ferredoxin-type protein NapH FZN31_RS08565 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) FZN31_RS08570 ENOG4105CUW cytochrome C-TYPE protein FZN31_RS08575 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) FZN31_RS08580 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) FZN31_RS08585 ENOG41060IM Heme exporter protein FZN31_RS08590 ENOG4105X3C heme exporter protein FZN31_RS08600 ENOG4105DA4 cytochrome c-type biogenesis protein FZN31_RS08605 ENOG4107QX9 Thiol disulfide interChange protein FZN31_RS08610 ENOG4105KWW Biogenesis protein FZN31_RS08615 ENOG4105WH1 Two component transcriptional regulator luxr family FZN31_RS08620 ENOG4108MGN ATP-binding component of a transport system FZN31_RS08630 ENOG4105E68 Sulfatase FZN31_RS08650 ENOG4105CFI type iii restriction protein res subunit FZN31_RS08655 ENOG4105I08 Pseudouridine synthase FZN31_RS08660 ENOG4105C2C drug resistance transporter, Bcr CflA FZN31_RS08665 ENOG4105HG6 FZN31_RS08670 ENOG4108JQ5 ABC transporter FZN31_RS08675 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FZN31_RS08680 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FZN31_RS08685 ENOG4105E43 Extracellular solute-binding protein, family 5 FZN31_RS08690 ENOG4105CXC rtn protein FZN31_RS08695 ENOG4107TT5 NLP P60 protein FZN31_RS08700 ENOG41076MN Phosphoesterase, PA-phosphatase related FZN31_RS08705 ENOG4105CKI cobalamin synthesis protein FZN31_RS08710 ENOG4105DEI Mannitol dehydrogenase FZN31_RS08720 ENOG4105KRS Proteinase inhibitor FZN31_RS08725 ENOG4105S8Q sugar efflux transporter FZN31_RS08730 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FZN31_RS08735 ENOG4105DE4 1-phosphofructokinase FZN31_RS08740 ENOG4105DM4 PTS System FZN31_RS08745 ENOG4105DD7 kinase (PfkB family FZN31_RS08750 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FZN31_RS08755 ENOG4105D9N nucleoside FZN31_RS08760 ENOG4108Y4K DNA-binding transcriptional activator FZN31_RS08770 ENOG4105D9N nucleoside FZN31_RS08775 ENOG4105DD7 kinase (PfkB family FZN31_RS08785 ENOG4105HMI Membrane FZN31_RS08790 ENOG4105DUM transcriptional regulator, lysR family FZN31_RS08795 ENOG4108IQI permease FZN31_RS08800 ENOG4105D05 Receptor FZN31_RS08805 ENOG4105CXY transporter FZN31_RS08810 ENOG4105EAC phosphoserine phosphatase FZN31_RS08815 ENOG4105EJQ L-serine dehydratase FZN31_RS08835 ENOG4105DHF Membrane FZN31_RS08840 ENOG41060NJ transcriptional regulator FZN31_RS08845 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FZN31_RS08850 ENOG4105C2J ABC transporter FZN31_RS08855 ENOG4108HWV )-transporter FZN31_RS08860 ENOG4107SJI Dehydrogenase FZN31_RS08865 ENOG4105BZ8 glutamate synthase FZN31_RS08870 ENOG4105Y9N Membrane FZN31_RS08875 ENOG4107GZ4 SanA protein FZN31_RS08885 ENOG41067MG lrgb family FZN31_RS08915 ENOG4108RXX maleylacetoacetate isomerase FZN31_RS08920 ENOG4105MSY salicylate hydroxylase FZN31_RS08925 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FZN31_RS08935 ENOG4105ETP RND efflux system, outer membrane lipoprotein FZN31_RS08940 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FZN31_RS08945 ENOG4105KHU inner membrane protein YohD FZN31_RS08950 ENOG41069YE inner membrane protein yohC FZN31_RS08955 ENOG41061WM D-Alanyl-D-Alanine FZN31_RS08960 ENOG4105CXG d-lactate dehydrogenase FZN31_RS08965 ENOG4107QK4 glycoside hydrolase, family 3 domain protein FZN31_RS08970 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system FZN31_RS08975 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component FZN31_RS08980 ENOG4108IJ8 ABC transporter FZN31_RS08985 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component FZN31_RS08995 ENOG4108XDN Transcriptional regulator FZN31_RS09000 ENOG4108HRK Histidine kinase FZN31_RS09005 ENOG4108NEV two component transcriptional regulator, LytTR family FZN31_RS09010 ENOG4108W15 Protein of unknown function (DUF1456) FZN31_RS09015 ENOG4108YCW (LipO)protein FZN31_RS09020 ENOG410903U zinc ion binding FZN31_RS09025 ENOG4105DEG Vwa containing coxe family protein FZN31_RS09030 ENOG4105RD5 FZN31_RS09035 ENOG4105KKX ATPase associated with various cellular activities aaa_5 FZN31_RS09045 ENOG4108KDT Molybdate metabolism regulator FZN31_RS09050 ENOG4108KDT Molybdate metabolism regulator FZN31_RS09055 ENOG4108KDT Molybdate metabolism regulator FZN31_RS09060 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FZN31_RS09065 ENOG4105D1F ATP-binding protein FZN31_RS09070 ENOG41067AK Protein of unknown function (DUF2574) FZN31_RS09075 ENOG41063W2 Fimbrial protein FZN31_RS09080 ENOG4108MQF Chaperone FZN31_RS09085 ENOG4105CW0 outer membrane usher protein FZN31_RS09090 ENOG410662B Type-1 fimbrial protein FZN31_RS09095 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly FZN31_RS09115 ENOG4105DWF phosphomethylpyrimidine kinase FZN31_RS09120 ENOG4108UQ1 hydrolase, family 25 FZN31_RS09125 ENOG4105FDP GntR family transcriptional regulator FZN31_RS09130 ENOG4108TFM Kinase, PfkB family FZN31_RS09135 ENOG4108KD5 ADP-ribosylation crystallin J1 FZN31_RS09140 ENOG4105EAA nucleoside FZN31_RS09145 ENOG4105EIE fructose-bisphosphate aldolase FZN31_RS09160 ENOG41082GB PTS system galactitol-specific transporter subunit IIA FZN31_RS09165 ENOG41090UW PTS System FZN31_RS09170 ENOG4105DT3 PTS system, galactitol-specific IIc component FZN31_RS09175 ENOG4107WTH Galactitol-1-phosphate dehydrogenase FZN31_RS09190 ENOG41076Z6 Uncharacterized protein yegR FZN31_RS09195 ENOG4105CFP Peptidase U32 FZN31_RS09205 ENOG4105X54 addiction module antidote protein FZN31_RS09210 ENOG4105KWI UPF0339 protein FZN31_RS09215 ENOG4105E3W Two component transcriptional regulator (Winged helix family FZN31_RS09220 ENOG4105EB3 Histidine kinase FZN31_RS09255 ENOG4108M24 von Willebrand factor, type A FZN31_RS09260 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase FZN31_RS09265 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding FZN31_RS09270 ENOG4105R8A Heat shock protein FZN31_RS09275 ENOG4105D03 DNA-3-methyladenine glycosylase II FZN31_RS09280 ENOG4105BZU Histidine kinase FZN31_RS09285 ENOG4105DBI uridine monophosphokinase FZN31_RS09295 ENOG4108GAE asmA family FZN31_RS09300 ENOG4105EE5 Membrane protein terC FZN31_RS09305 ENOG4105DAY polysaccharide export protein FZN31_RS09310 ENOG4105KJF protein tyrosine phosphatase FZN31_RS09315 ENOG4105D75 Capsular exopolysaccharide family FZN31_RS09320 ENOG41090RK glycosyl transferase FZN31_RS09325 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB FZN31_RS09330 ENOG4107RXY Glycosyl transferase FZN31_RS09335 ENOG4108NYJ Colanic acid FZN31_RS09340 ENOG4105ECJ Glycosyl Transferase FZN31_RS09345 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF FZN31_RS09350 ENOG4105C0K Gdp-mannose 4,6-dehydratase FZN31_RS09355 ENOG4105C30 Nad-dependent epimerase dehydratase FZN31_RS09360 ENOG4105FGF GDP-mannose mannosyl hydrolase FZN31_RS09365 ENOG4106CD9 glycosyl transferase group 1 FZN31_RS09370 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FZN31_RS09375 ENOG4107QKV phosphomannomutase FZN31_RS09380 ENOG4105D3Q Sugar transferase FZN31_RS09385 ENOG4105PSV Polysaccharide Biosynthesis Protein FZN31_RS09390 ENOG4105C74 pyruvyl transferase FZN31_RS09395 ENOG4107T8Q Glycosyl transferase (Group 1 FZN31_RS09400 ENOG4105G1A colanic acid biosynthesis protein FZN31_RS09405 ENOG4105DMT epimerase dehydratase FZN31_RS09410 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FZN31_RS09415 ENOG4108RYC glycosyltransferase FZN31_RS09425 ENOG4105C3Q Glycosyl transferase, family 2 FZN31_RS09450 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FZN31_RS09455 ENOG4105C6Y Udp-glucose 6-dehydrogenase FZN31_RS09460 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) FZN31_RS09465 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FZN31_RS09480 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FZN31_RS09485 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FZN31_RS09495 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FZN31_RS09510 ENOG4105VTW prevent-host-death family FZN31_RS09515 ENOG4105KRQ Addiction module toxin, Txe YoeB family FZN31_RS09520 ENOG4108535 NAD dependent epimerase/dehydratase family FZN31_RS09525 ENOG4105EQ1 Transcriptional regulator FZN31_RS09535 ENOG4105CUB amino acid FZN31_RS09540 ENOG4105CUC YeeE YedE family protein FZN31_RS09550 ENOG4105CJB Exodeoxyribonuclease I FZN31_RS09555 ENOG4105DZ1 carboxypeptidase FZN31_RS09560 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) FZN31_RS09590 ENOG4105EKQ RNA-directed DNA polymerase FZN31_RS09620 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles FZN31_RS09625 ENOG4106WJE Protein of unknown function (DUF987) FZN31_RS09630 ENOG4108YGG dna repair protein FZN31_RS09635 ENOG4105MFG Antirestriction protein FZN31_RS09640 ENOG4106H6R UPF0380 protein FZN31_RS09655 ENOG4108PZQ Inner membrane protein YeeR FZN31_RS09660 ENOG4105F4K antigen 43 FZN31_RS09670 ENOG4108P8R FZN31_RS09685 ENOG4105KF5 hemolysin expression-modulating protein FZN31_RS09720 ENOG4105F9F transposase FZN31_RS09730 ENOG4108YZT Adenosylcobinamide kinase FZN31_RS09745 ENOG4108PXI ErfK YbiS YcfS YnhG FZN31_RS09755 ENOG4106P55 Transcriptional regulator FZN31_RS09760 ENOG4107R11 Transcriptional regulator FZN31_RS09800 ENOG4105CDY transcriptional regulatory protein FZN31_RS09805 ENOG4105FYV Amp nucleosidase FZN31_RS09810 ENOG4105CSH Transporter FZN31_RS09820 ENOG4105TNG K13735 adhesin invasin FZN31_RS09830 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) FZN31_RS09840 ENOG4108VKM cytochrome b561 FZN31_RS09845 ENOG4108MEK Metal-binding protein YodA FZN31_RS09860 ENOG4105VT2 5-hydroxyisourate hydrolase FZN31_RS09865 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FZN31_RS09870 ENOG4107ZY3 Histidine kinase FZN31_RS09880 ENOG4105ZIT Porin Gram-negative type FZN31_RS09885 ENOG4105Y0K Inner membrane protein YedR FZN31_RS09890 ENOG4105EST Metal Dependent Phosphohydrolase FZN31_RS09895 ENOG4105DVF Cytosine-specific methyltransferase FZN31_RS09900 ENOG41090BB DNA mismatch endonuclease (vsr) FZN31_RS09905 ENOG4105FDR Membrane FZN31_RS09910 ENOG4105CKW Inner membrane protein yedI FZN31_RS09915 ENOG4105VNZ cytoplasmic protein FZN31_RS09930 ENOG4105YX3 cellular response to acidity FZN31_RS09940 ENOG4107TKS colanic acid capsular biosynthesis activation protein A FZN31_RS09945 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FZN31_RS09950 ENOG4105VS8 Flagellar biosynthetic protein fliq FZN31_RS09955 ENOG4105CN7 Flagellar biosynthetic protein FliP FZN31_RS09960 ENOG4105K0P flagellar biosynthesis protein FZN31_RS09965 ENOG4105DD5 Flagellar motor switch protein FZN31_RS09970 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FZN31_RS09975 ENOG4107ZI8 flagellar basal body-associated protein flil FZN31_RS09980 ENOG4105WF4 Flagellar hook-length control protein FZN31_RS09985 ENOG4105GSA Flagellar export protein flij FZN31_RS09990 ENOG4108JIR Flagellum-specific ATP synthase FZN31_RS09995 ENOG41090PJ Flagellar assembly protein FZN31_RS10000 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FZN31_RS10005 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FZN31_RS10015 ENOG410814C multidrug resistance protein FZN31_RS10020 ENOG4108V1U phospholipid-binding protein FZN31_RS10025 ENOG4108UQN AraC family transcriptional regulator FZN31_RS10030 ENOG4108RS6 transposase FZN31_RS10035 ENOG4105D7V transposase FZN31_RS10040 ENOG4108RAV Conserved protein FZN31_RS10045 ENOG4105KSU Redox protein FZN31_RS10050 ENOG41066VF YeeE YedE family protein FZN31_RS10055 ENOG4108W9D (LipO)protein FZN31_RS10060 ENOG4105E5K Alpha-amylase FZN31_RS10070 ENOG4105MQ3 flagellar protein FliS FZN31_RS10075 ENOG4105DTS flagellar hook-associated FZN31_RS10080 ENOG4105I03 Flagellin FZN31_RS10085 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FZN31_RS10090 ENOG4108M9K flagella biosynthesis protein FliZ FZN31_RS10095 ENOG4105EAB amino acid AbC transporter FZN31_RS10105 ENOG4105E5Q amino acid AbC transporter FZN31_RS10110 ENOG4105CDA abc transporter atp-binding protein FZN31_RS10115 ENOG4105VJY transcriptional regulator FZN31_RS10120 ENOG4105XVG cytoplasmic protein FZN31_RS10130 ENOG4105WH1 Two component transcriptional regulator luxr family FZN31_RS10140 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FZN31_RS10160 ENOG4106RHG Yeca family FZN31_RS10165 ENOG4105E0U tyrosine-specific transport protein FZN31_RS10170 ENOG4105VVZ metal-binding protein FZN31_RS10175 ENOG41090A1 ferritin FZN31_RS10180 ENOG4105P23 (LipO)protein FZN31_RS10190 ENOG4105N4N Protein of unknown function (DUF2766) FZN31_RS10195 ENOG4108UEC Ferritin-like protein FZN31_RS10200 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator FZN31_RS10205 ENOG4105C2J ABC transporter FZN31_RS10210 ENOG4105CNN ABC, transporter FZN31_RS10215 ENOG4108K4C ec 3.1.3.12 FZN31_RS10225 ENOG4108VA4 Universal stress protein FZN31_RS10235 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region FZN31_RS10240 ENOG4107RD7 Flagellar Motor Protein, MotA FZN31_RS10245 ENOG4105ER2 Ompa motb domain protein FZN31_RS10250 ENOG4105CBS Chea signal transduction histidine kinase FZN31_RS10255 ENOG4108V3W Chemotaxis protein, CheW FZN31_RS10260 ENOG4105C8Q Methyl-accepting chemotaxis FZN31_RS10265 ENOG4105C8Q Methyl-accepting chemotaxis FZN31_RS10270 ENOG4105BZU Histidine kinase FZN31_RS10275 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FZN31_RS10280 ENOG4108VYJ response regulator receiver protein FZN31_RS10285 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) FZN31_RS10290 ENOG4105D00 flagellar biosynthetic protein flhB FZN31_RS10295 ENOG4105D7B Flagellar biosynthesis protein flha FZN31_RS10300 ENOG4105W13 flagellar protein FZN31_RS10315 ENOG4106ZCM YecM protein FZN31_RS10325 ENOG4105CUW cytochrome C-TYPE protein FZN31_RS10330 ENOG4107QY8 reductase FZN31_RS10345 ENOG4105WJG Glutathione FZN31_RS10350 ENOG41081XQ Conserved Protein FZN31_RS10355 ENOG4105D3W isochorismatase FZN31_RS10365 ENOG4108TIT dATP pyrophosphohydrolase FZN31_RS10370 ENOG4105CDY transcriptional regulatory protein FZN31_RS10380 ENOG4107S01 Repressor protein MetJ FZN31_RS10410 ENOG4105FAV ABC, transporter FZN31_RS10415 ENOG4105FDK ABC transporter FZN31_RS10420 ENOG4105NXV High-affinity zinc uptake system protein FZN31_RS10425 ENOG4105DR5 peptidase FZN31_RS10430 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FZN31_RS10435 ENOG4105CA9 Pyruvate kinase FZN31_RS10440 ENOG4106KNT transcriptional regulator FZN31_RS10445 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FZN31_RS10450 ENOG4105C01 Dihydroxy-acid dehydratase FZN31_RS10455 ENOG4108UHU Aldolase FZN31_RS10465 ENOG4105X2V dna damage-inducible protein FZN31_RS10470 ENOG4105RSZ secreted protein FZN31_RS10475 ENOG4108Q2J Inner membrane protein YebE FZN31_RS10480 ENOG4105CUG Oligopeptidase b FZN31_RS10485 ENOG4105UMD exodeoxyribonuclease X FZN31_RS10490 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FZN31_RS10495 ENOG4105MPK DNA polymerase III subunit theta FZN31_RS10500 ENOG4105FXM Copper resistance protein FZN31_RS10505 ENOG4108PNC copper resistance FZN31_RS10510 ENOG4105NKT exported protein FZN31_RS10515 ENOG4108R1E Serine threonine protein phosphatase 1 FZN31_RS10520 ENOG4105UVW uncharacterized protein yebW FZN31_RS10525 ENOG4105WT8 Protein of unknown function (DUF1480) FZN31_RS10535 ENOG4105DY2 Paraquat-inducible protein b FZN31_RS10540 ENOG4105H2K paraquat-inducible protein a FZN31_RS10545 ENOG4108ZGC gaf domain protein FZN31_RS10555 ENOG4105CN1 protease FZN31_RS10565 ENOG4105C0R drug resistance transporter emrb qaca subfamily FZN31_RS10570 ENOG4105J4Q Transcriptional regulator FZN31_RS10575 ENOG4105TIK FZN31_RS10585 ENOG4105Q3Y exported protein FZN31_RS10590 ENOG410610J Protein of unknown function (DUF2627) FZN31_RS10595 ENOG4105VEQ Cold shock protein FZN31_RS10600 ENOG4105DHI Methyltransferase FZN31_RS10615 ENOG4105F3R pts system mannose fructose sorbose family iid FZN31_RS10620 ENOG4105ETZ PTS System FZN31_RS10625 ENOG4108EQA pts system FZN31_RS10630 ENOG4105EE5 Membrane protein terC FZN31_RS10635 ENOG4107XTP (EAL) domain protein FZN31_RS10640 ENOG4105EJQ L-serine dehydratase FZN31_RS10645 ENOG4105P8F nudix hydrolase FZN31_RS10650 ENOG4105CRQ synthase (Component I) FZN31_RS10660 ENOG4105V2F Uncharacterized protein yoac FZN31_RS10665 ENOG4105M4H endoribonuclease L-psp FZN31_RS10670 ENOG4105DVT helicase FZN31_RS10675 ENOG41072GX Peptidase M22 Glycoprotease FZN31_RS10680 ENOG4105Y4Z Outer Membrane Lipoprotein FZN31_RS10685 ENOG4105CEY Amp-dependent synthetase and ligase FZN31_RS10690 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FZN31_RS10695 ENOG4105E3J oxidoreductase FZN31_RS10700 ENOG4105DVW rieske (2Fe-2S) FZN31_RS10705 ENOG4105C94 Transporter FZN31_RS10710 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FZN31_RS10715 ENOG4105EJC lysr family transcriptional regulator FZN31_RS10725 ENOG4108YS1 cytoplasmic protein FZN31_RS10730 ENOG4105YP6 Domain of unknown function (DUF1869) FZN31_RS10735 ENOG4105Y3U Transglycosylase-associated protein FZN31_RS10745 ENOG4106G4W FZN31_RS10750 ENOG410620I Diguanylate cyclase FZN31_RS10755 ENOG4105UCG Domain of unknown function (DUF333) FZN31_RS10760 ENOG4105K78 MarR family Transcriptional regulator FZN31_RS10765 ENOG4105DJ2 Major Facilitator Superfamily FZN31_RS10770 ENOG4105R1U AraC Family Transcriptional Regulator FZN31_RS10785 ENOG4108KXH Ybak prolyl-tRNA synthetase associated FZN31_RS10790 ENOG4108KHP Diguanylate cyclase FZN31_RS10795 ENOG4106KTS Inner membrane protein yeaI FZN31_RS10805 ENOG4105CYN Serine protein kinase FZN31_RS10810 ENOG4105GNX MltA-interacting MipA family protein FZN31_RS10815 ENOG4105CV8 reductase FZN31_RS10820 ENOG4105DSB aldose 1-epimerase FZN31_RS10825 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FZN31_RS10835 ENOG4105VUT cytoplasmic protein FZN31_RS10840 ENOG4108RWI nicotinamidase FZN31_RS10845 ENOG4105HDK L-asparaginase FZN31_RS10855 ENOG4105D07 Signal peptide peptidase, SppA FZN31_RS10860 ENOG41069NU Nitroreductase FZN31_RS10865 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) FZN31_RS10870 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FZN31_RS10875 ENOG4105D82 Glutamate dehydrogenase FZN31_RS10880 ENOG4105MTM Protein of unknown function (DUF1496) FZN31_RS10885 ENOG4105M6F mutator MutT protein FZN31_RS10890 ENOG4108T9J Cdp-alcohol phosphatidyltransferase FZN31_RS10895 ENOG4107RM6 sulfurtransferase FZN31_RS10900 ENOG4108VGW abc transporter atp-binding protein FZN31_RS10905 ENOG4105CXZ ABC transporter, permease FZN31_RS10910 ENOG4105VNH ABC transporter solute-binding protein FZN31_RS10915 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) FZN31_RS10920 ENOG4108N5C SNARE associated Golgi protein-related protein FZN31_RS10925 ENOG4108KCW iron-sulfur cluster binding FZN31_RS10930 ENOG4108RSN SNARE associated Golgi FZN31_RS10935 ENOG4105CGK Exodeoxyribonuclease III FZN31_RS10960 ENOG4107UI5 Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity) FZN31_RS10965 ENOG4108SPG Periplasmic Protein FZN31_RS10975 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) FZN31_RS10985 ENOG4105KKI DNA-binding transcriptional activator OsmE FZN31_RS10990 ENOG4105VZJ PTS System FZN31_RS10995 ENOG4105CK1 PTS System FZN31_RS11000 ENOG4105VCP PTS System FZN31_RS11010 ENOG4105F8D glycoside hydrolase family 4 FZN31_RS11015 ENOG410901P UPF0249 protein FZN31_RS11020 ENOG4105CH6 catalase FZN31_RS11035 ENOG4108ETY sodium dicarboxylate symporter FZN31_RS11040 ENOG4107K5X Membrane-bound metal-dependent hydrolase FZN31_RS11045 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 FZN31_RS11050 ENOG4107PN8 YfeABCD locus regulator FZN31_RS11055 ENOG4105FGM Fructosamine kinase FZN31_RS11060 ENOG4105P10 Uncharacterized protein ydiZ FZN31_RS11065 ENOG4105DE4 1-phosphofructokinase FZN31_RS11070 ENOG4108NE3 Salt-induced outer membrane protein FZN31_RS11095 ENOG41082NX 50s ribosomal protein l35 FZN31_RS11100 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FZN31_RS11115 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FZN31_RS11130 ENOG4108V06 Glutathione peroxidase FZN31_RS11140 ENOG4108QBX (LipO)protein FZN31_RS11145 ENOG4108TC0 Diguanylate phosphodiesterase FZN31_RS11155 ENOG4106EDX Hemin uptake protein FZN31_RS11160 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FZN31_RS11170 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FZN31_RS11175 ENOG4107QPK )-transporter FZN31_RS11180 ENOG4105C5I Dehydrogenase FZN31_RS11190 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FZN31_RS11195 ENOG4105CEY Amp-dependent synthetase and ligase FZN31_RS11200 ENOG41090P5 ferredoxin-like protein FZN31_RS11205 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FZN31_RS11210 ENOG4105C10 Electron transfer flavoprotein FZN31_RS11215 ENOG4105CV7 Electron transfer flavoprotein FZN31_RS11220 ENOG4105W4W Transcriptional regulator FZN31_RS11225 ENOG4105C1G acyl-Coa dehydrogenase FZN31_RS11230 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FZN31_RS11245 ENOG4105EMV Major Facilitator FZN31_RS11250 ENOG4105EMV Major Facilitator FZN31_RS11255 ENOG4105SUA Ydil protein FZN31_RS11265 ENOG4105IPI Membrane FZN31_RS11270 ENOG4105CQB FAD linked oxidase domain protein FZN31_RS11275 ENOG4105KA0 thioesterase Superfamily protein FZN31_RS11280 ENOG410671Z uncharacterized protein ydiH FZN31_RS11285 ENOG4108Z4V iron-sulfur cluster assembly FZN31_RS11290 ENOG4105DIW FeS assembly protein SUFB FZN31_RS11295 ENOG4105C3K feS assembly ATPase SufC FZN31_RS11300 ENOG4105JRK feS assembly protein SufD FZN31_RS11315 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FZN31_RS11320 ENOG4105KMX major outer membrane lipoprotein FZN31_RS11325 ENOG4105CA9 Pyruvate kinase FZN31_RS11330 ENOG4105RFR Protein of unknown function (DUF2767) FZN31_RS11335 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein FZN31_RS11340 ENOG4105WE2 aldehyde ferredoxin oxidoreductase FZN31_RS11345 ENOG4105JVW FZN31_RS11350 ENOG4108393 oxidoreductase Fe-S subunit FZN31_RS11355 ENOG4108NWD Cytochrome FZN31_RS11360 ENOG4108Y7C Conserved Protein FZN31_RS11365 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain FZN31_RS11370 ENOG4105N0V mono-oxygenase ydhR FZN31_RS11395 ENOG4108R6K riboflavin synthase, subunit alpha FZN31_RS11400 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FZN31_RS11405 ENOG4105CZQ inner membrane transport protein YdhC FZN31_RS11410 ENOG4105F52 Transcriptional regulator FZN31_RS11425 ENOG4105F27 Major Facilitator FZN31_RS11430 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FZN31_RS11435 ENOG4105K4H Nlp p60 protein FZN31_RS11440 ENOG4105M2J Glutaredoxin FZN31_RS11445 ENOG4107QRT dEAD DEAH box helicase FZN31_RS11455 ENOG4108UYE Lactoylglutathione lyase FZN31_RS11460 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FZN31_RS11465 ENOG4108WUH Transcriptional regulator, TetR family FZN31_RS11470 ENOG4105XZD Fe-S protein FZN31_RS11475 ENOG4107RGM aldo keto reductase FZN31_RS11480 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FZN31_RS11485 ENOG4105DSW Fusaric acid resistance protein FZN31_RS11490 ENOG4105Y49 secretion protein, HlyD family FZN31_RS11505 ENOG4108XTF Outer Membrane Lipoprotein FZN31_RS11515 ENOG410642K Lysozyme inhibitor FZN31_RS11530 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) FZN31_RS11535 ENOG4108K3A Glutathione S-transferase FZN31_RS11540 ENOG4105DUX Transporter FZN31_RS11545 ENOG4105CSM endonuclease III FZN31_RS11555 ENOG4108UQQ Electron transport complex FZN31_RS11580 ENOG4105M9B inner membrane protein ydgK FZN31_RS11585 ENOG4105QZ5 OriC-binding nucleoid-associated protein FZN31_RS11590 ENOG4106C6R beta-lactam resistance protein FZN31_RS11595 ENOG4105D9R oxidoreductase FZN31_RS11605 ENOG4105C87 Aminotransferase class I and II FZN31_RS11610 ENOG4105CI1 PTS System FZN31_RS11615 ENOG4107P2S Transcriptional regulator FZN31_RS11620 ENOG4107ZQV short-chain dehydrogenase reductase FZN31_RS11625 ENOG4105XEA Tetr family transcriptional regulator FZN31_RS11630 ENOG4105CNT hydrolase family 2 FZN31_RS11635 ENOG4105CT4 transporter FZN31_RS11640 ENOG4108QNI outer membrane porin protein FZN31_RS11645 ENOG4106J39 exported protein FZN31_RS11650 ENOG4105EIP mannose-6-phosphate isomerase FZN31_RS11655 ENOG4107GFK fumarate FZN31_RS11660 ENOG4105C9Q fumarate hydratase class II FZN31_RS11670 ENOG4105JJR Histidine kinase FZN31_RS11675 ENOG4107EXC regulatoR FZN31_RS11680 ENOG4105RA2 Membrane FZN31_RS11685 ENOG410642E Short chain dehydrogenase FZN31_RS11690 ENOG4105D5Q Arginine ornithine antiporter FZN31_RS11695 ENOG4105C5D exported protein FZN31_RS11700 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FZN31_RS11705 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FZN31_RS11710 ENOG4105DSF transport protein FZN31_RS11725 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap FZN31_RS11740 ENOG4105D94 Major Facilitator Superfamily FZN31_RS11745 ENOG4106NZI LysR family Transcriptional regulator FZN31_RS11750 ENOG4105DAG ROK family FZN31_RS11755 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FZN31_RS11760 ENOG4105CMQ Chloride channel FZN31_RS11765 ENOG4108NEM leader-binding protein dmsD FZN31_RS11770 ENOG4107KGK dmso reductase anchor subunit FZN31_RS11775 ENOG4105QAX Iron-sulfur FZN31_RS11780 ENOG4105C3J Cysteine desulfurase FZN31_RS11785 ENOG4107QY8 reductase FZN31_RS11790 ENOG4105KBG Protein of unknown function (DUF1161) FZN31_RS11800 ENOG4108MK9 spermidine N(1)-acetyltransferase FZN31_RS11815 ENOG4105CXK mandelate racemase muconate lactonizing FZN31_RS11820 ENOG4105CPQ Dehydrogenase FZN31_RS11830 ENOG4107R08 Integrase FZN31_RS11845 ENOG4106G8A Qin prophage FZN31_RS11905 ENOG4105WI6 cell killing protein encoded within cryptic prophage FZN31_RS11915 ENOG4108MXB Protein of unknown function (DUF968) FZN31_RS11920 ENOG4105HGD Antitermination protein FZN31_RS11935 ENOG4105VEQ Cold shock protein FZN31_RS11940 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FZN31_RS11955 ENOG4108YV9 Protein of unknown function (DUF2514) FZN31_RS11960 ENOG4105VEQ Cold shock protein FZN31_RS11975 ENOG4106IAW FZN31_RS11980 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation FZN31_RS12005 ENOG4105DFP Integrase FZN31_RS12060 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FZN31_RS12085 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FZN31_RS12160 ENOG410685N tail fiber protein FZN31_RS12165 ENOG4105UZW Tail fiber assembly protein FZN31_RS12170 ENOG4105MN3 Resolvase FZN31_RS12175 ENOG4105W3V DNA-binding, transcriptional regulator FZN31_RS12190 ENOG4105DEI Mannitol dehydrogenase FZN31_RS12195 ENOG41061EV selenium-binding protein YdfZ FZN31_RS12200 ENOG4107XBN GntR Family Transcriptional Regulator FZN31_RS12205 ENOG4105EMU Dehydrogenase FZN31_RS12210 ENOG4105DGW oligopeptidase A FZN31_RS12215 ENOG4108WTK competence damage-inducible protein FZN31_RS12220 ENOG4108YDI single-species biofilm formation on inanimate substrate FZN31_RS12225 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria FZN31_RS12235 ENOG4105E5W Transporter FZN31_RS12240 ENOG4108594 Permease of the drug metabolite transporter FZN31_RS12245 ENOG4106DNR multiple antibiotic resistance protein FZN31_RS12250 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF FZN31_RS12255 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FZN31_RS12275 ENOG4105EGI Transcriptional regulator FZN31_RS12280 ENOG4105C26 Dehydrogenase FZN31_RS12285 ENOG4105CSV Glutaminase FZN31_RS12290 ENOG4105M0C cytoplasmic protein FZN31_RS12295 ENOG4105BZU Histidine kinase FZN31_RS12305 ENOG4105FFC UPF0187 protein FZN31_RS12310 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) FZN31_RS12315 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound FZN31_RS12325 ENOG4105D4B ABC, transporter FZN31_RS12330 ENOG4105F5R ABC transporter FZN31_RS12340 ENOG4105C2J ABC transporter FZN31_RS12360 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein FZN31_RS12365 ENOG4105CAF HipA N-terminal domain protein FZN31_RS12420 ENOG4108KQ5 Integrase catalytic subunit FZN31_RS12435 ENOG4108RQP Major type 1 subunit fimbrin FZN31_RS12440 ENOG4108NAE Fimbrial chaperone protein FZN31_RS12445 ENOG4105CW0 outer membrane usher protein FZN31_RS12450 ENOG4108WDE Fimbrial protein FZN31_RS12455 ENOG4106318 fimbrial-like protein YdeR FZN31_RS12460 ENOG4106PIH fimbrial-like protein ydeQ FZN31_RS12465 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FZN31_RS12480 ENOG4105ENH Sulfatase FZN31_RS12485 ENOG4105C4X radical SAM domain protein FZN31_RS12510 ENOG4108KTG Membrane protein, drug metabolite transporter FZN31_RS12545 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor FZN31_RS12550 ENOG4105PE1 Receptor FZN31_RS12555 ENOG4107RAN Peptidase, M16 FZN31_RS12560 ENOG4105CVK Glutamate decarboxylase FZN31_RS12565 ENOG4105E5D amino acid FZN31_RS12570 ENOG4105F32 YngK protein FZN31_RS12580 ENOG4105BZU Histidine kinase FZN31_RS12585 ENOG4108UQS dipeptidase FZN31_RS12590 ENOG4105DEF Extracellular solute-binding protein, family 5 FZN31_RS12595 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FZN31_RS12600 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FZN31_RS12605 ENOG4105C3U ABC transporter FZN31_RS12610 ENOG4107H6U ABC transporter FZN31_RS12615 ENOG4108Z9K Osmotically inducible protein FZN31_RS12620 ENOG4105TPS biofilm-dependent modulation protein FZN31_RS12625 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein FZN31_RS12635 ENOG4105DQ4 alcohol dehydrogenase FZN31_RS12645 ENOG41084S7 Plasmid maintenance system antidote protein FZN31_RS12650 ENOG4108MG3 formate dehydrogenase FZN31_RS12655 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FZN31_RS12665 ENOG4105RPH Inner membrane protein YddG FZN31_RS12675 ENOG4108UI3 Leucine Rich repeat FZN31_RS12685 ENOG4107QND Nitrite extrusion protein FZN31_RS12690 ENOG4105CRU nitrate reductase, alpha subunit FZN31_RS12695 ENOG4108IUE nitrate reductase beta subunit FZN31_RS12700 ENOG4108NZN Respiratory nitrate reductase 2 delta chain FZN31_RS12705 ENOG4105D0D Nitrate reductase 2, gamma subunit FZN31_RS12710 ENOG4105JAB phenazine biosynthesis protein, phzf family FZN31_RS12715 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FZN31_RS12720 ENOG4108MEJ flavin reductase domain protein FZN31_RS12745 ENOG4105CS6 Rhs element vgr protein FZN31_RS12755 ENOG4108N27 Glutathione S-transferase FZN31_RS12760 ENOG4105C85 amino acid FZN31_RS12765 ENOG4108NS2 receptor FZN31_RS12770 ENOG4105CHB tonB-dependent Receptor FZN31_RS12775 ENOG4108WYP Transcriptional regulator FZN31_RS12780 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FZN31_RS12785 ENOG4108Z7F N-acetyltransferase FZN31_RS12790 ENOG4108T9Y Inner membrane protein ydcZ FZN31_RS12795 ENOG4105R71 cytoplasmic protein FZN31_RS12800 ENOG410654E Membrane FZN31_RS12815 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component FZN31_RS12820 ENOG4105D81 ABC transporter, permease FZN31_RS12825 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS12830 ENOG4107TYH extracellular solute-binding protein family 1 FZN31_RS12835 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FZN31_RS12865 ENOG4105RR0 Protein of unknown function (DUF2554) FZN31_RS12870 ENOG4105CFP Peptidase U32 FZN31_RS12875 ENOG4108JCI Transcriptional regulator FZN31_RS12880 ENOG4105DKK Benzoate FZN31_RS12885 ENOG4108KKZ (LipO)protein FZN31_RS12890 ENOG41088CC tellurite resistance protein tehB FZN31_RS12895 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein FZN31_RS12900 ENOG4107WE3 acetyltransferase YdcK FZN31_RS12905 ENOG4108Z9I -acetyltransferase FZN31_RS12910 ENOG4105Z2P Protein of unknown function (DUF465) FZN31_RS12920 ENOG4105E32 cytoplasmic protein FZN31_RS12925 ENOG4105DDW LysR family Transcriptional regulator FZN31_RS12930 ENOG4105C8Q Methyl-accepting chemotaxis FZN31_RS12935 ENOG4107NK6 Hok/gef family FZN31_RS12940 ENOG4105UPP uncharacterized protein ydcA FZN31_RS12945 ENOG4105CPW cytochrome b561 FZN31_RS12950 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FZN31_RS12955 ENOG4105C26 Dehydrogenase FZN31_RS12960 ENOG4107DB1 DUF218 domain FZN31_RS12965 ENOG4105CQ7 ATP-dependent helicase FZN31_RS12975 ENOG41077RS Phosphatase FZN31_RS12980 ENOG4105E8V Alpha Beta Hydrolase Fold protein FZN31_RS12985 ENOG4108HPI phosphatidate Cytidylyltransferase FZN31_RS12990 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase FZN31_RS13000 ENOG4107S5I aldo keto reductase FZN31_RS13005 ENOG4107EF2 surface-exposed virulence protein FZN31_RS13010 ENOG4105WXT Conserved Protein FZN31_RS13015 ENOG410689M (LipO)protein FZN31_RS13020 ENOG4107H52 Dicarboxylate transport FZN31_RS13025 ENOG4105C5I Dehydrogenase FZN31_RS13030 ENOG41090X5 Heat shock protein hslJ FZN31_RS13040 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FZN31_RS13045 ENOG4105FCK Membrane FZN31_RS13050 ENOG4108RW8 Universal stress protein F FZN31_RS13060 ENOG4105C1J atp-dependent rna helicase FZN31_RS13070 ENOG4105BZU Histidine kinase FZN31_RS13075 ENOG4108DG9 Smr protein MutS2 FZN31_RS13080 ENOG4106KR7 LysR family Transcriptional regulator FZN31_RS13085 ENOG4105CH2 amidohydrolase FZN31_RS13090 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B FZN31_RS13095 ENOG4105CFC Transporter FZN31_RS13100 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FZN31_RS13105 ENOG4105DS0 Transcriptional regulator, Crp Fnr family FZN31_RS13110 ENOG4105Q9Y Universal stress protein FZN31_RS13115 ENOG4105S5I Membrane FZN31_RS13120 ENOG4105D64 Mechanosensitive ion channel FZN31_RS13125 ENOG4107QSI ABC, transporter FZN31_RS13130 ENOG4105KXI murein peptide amidase A FZN31_RS13135 ENOG4107S8C mandelate racemase muconate lactonizing FZN31_RS13140 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FZN31_RS13150 ENOG4108JU8 Transcriptional regulator FZN31_RS13160 ENOG4105CM6 amino acid regulated cytosolic protein FZN31_RS13165 ENOG4105FKQ transcriptional regulator FZN31_RS13170 ENOG4107EFV Outer membrane protein G FZN31_RS13175 ENOG4108IJ9 (ABC) transporter FZN31_RS13180 ENOG4107URF beta-phospho-glucomutase FZN31_RS13185 ENOG4105C71 hydrolase family 65, central catalytic FZN31_RS13190 ENOG4105CK5 oxidoreductase FZN31_RS13195 ENOG4107TYA transient receptor potential locus FZN31_RS13200 ENOG4107RRD Dehydrogenase FZN31_RS13205 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FZN31_RS13210 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component FZN31_RS13215 ENOG4105WEM extracellular solute-binding protein FZN31_RS13220 ENOG4107QW3 Sucrose phosphorylase FZN31_RS13225 ENOG4105K8Z Phage shock protein FZN31_RS13230 ENOG4105NNG Peripheral inner membrane phage-shock protein FZN31_RS13235 ENOG4105FM1 phage shock protein C FZN31_RS13240 ENOG4105YYT phage shock protein B FZN31_RS13245 ENOG41087YS Phage shock protein A FZN31_RS13250 ENOG4105E51 psp operon transcriptional activator FZN31_RS13255 ENOG4108JPW Aminotransferase FZN31_RS13260 ENOG4105CJP fad dependent oxidoreductase FZN31_RS13265 ENOG4105C26 Dehydrogenase FZN31_RS13270 ENOG4107VRI Transcriptional regulator FZN31_RS13275 ENOG4108Z86 Glutamine amidotransferase FZN31_RS13280 ENOG4105CFQ glutamine synthetase FZN31_RS13290 ENOG4105CUB amino acid FZN31_RS13295 ENOG4105N0E Protein of unknown function (DUF2543) FZN31_RS13300 ENOG4108HIY periplasmic FZN31_RS13305 ENOG4108I5W peptide transport system, permease protein FZN31_RS13310 ENOG4108EU3 peptide transport system, permease FZN31_RS13315 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein FZN31_RS13320 ENOG4108JQ2 peptide transport system atp-binding protein FZN31_RS13325 ENOG4105C2C drug resistance transporter, Bcr CflA FZN31_RS13330 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FZN31_RS13340 ENOG4105C1P efflux transporter, rnd family, mfp subunit FZN31_RS13345 ENOG41067SE Tetr family transcriptional regulator FZN31_RS13350 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FZN31_RS13355 ENOG4105Q4T oxidoreductase FZN31_RS13370 ENOG4105BZU Histidine kinase FZN31_RS13380 ENOG4105N2W Transcriptional regulator FZN31_RS13385 ENOG41061RM osmotically inducible lipoprotein FZN31_RS13390 ENOG4108ZJT translation initiation factor, Sui1 FZN31_RS13395 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) FZN31_RS13400 ENOG4105CFV Tetratricopeptide repeat protein FZN31_RS13405 ENOG4105Q4A inner membrane protein yciS FZN31_RS13410 ENOG4105EYK Phosphatidylglycerophosphatase B FZN31_RS13420 ENOG4107QM5 aconitate hydratase FZN31_RS13440 ENOG4107R11 Transcriptional regulator FZN31_RS13445 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FZN31_RS13450 ENOG4105RKX Protein of unknown function (DUF2498) FZN31_RS13455 ENOG4105ERU peptidase FZN31_RS13460 ENOG4105UBK short-chain dehydrogenase reductase FZN31_RS13465 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FZN31_RS13480 ENOG4105FE9 pseudouridine synthase FZN31_RS13485 ENOG4107RTD sua5 ycio yrdc ywlc family protein FZN31_RS13490 ENOG4105DB7 PHP domain protein FZN31_RS13500 ENOG4105CRQ synthase (Component I) FZN31_RS13505 ENOG4108EFP Anthranilate synthase component II FZN31_RS13510 ENOG4105DK0 Indole-3-glycerol phosphate synthase FZN31_RS13520 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) FZN31_RS13530 ENOG4108Z9Z response to DNA damage stimulus FZN31_RS13535 ENOG4108N8X transition metal ion binding FZN31_RS13540 ENOG4105EIF outer membrane protein W FZN31_RS13560 ENOG4105NAU thioesterase Superfamily protein FZN31_RS13565 ENOG410822N TonB family FZN31_RS13570 ENOG4105K9H YciI-like protein FZN31_RS13575 ENOG4107SVH Potassium channel protein FZN31_RS13595 ENOG4108JQ7 (ABC) transporter FZN31_RS13600 ENOG4105C3U ABC transporter FZN31_RS13605 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FZN31_RS13615 ENOG4108J59 Extracellular solute-binding protein, family 5 FZN31_RS13625 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FZN31_RS13630 ENOG4108EKI Dehydrogenase FZN31_RS13635 ENOG4107104 thymidine kinase FZN31_RS13640 ENOG4108SAU DNA-binding protein H-ns FZN31_RS13645 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FZN31_RS13650 ENOG4105I93 response regulator FZN31_RS13655 ENOG4105D78 K07001 NTE family protein FZN31_RS13665 ENOG4105CIY formyltetrahydrofolate deformylase FZN31_RS13700 ENOG41076YT nitrate reductase, gamma subunit FZN31_RS13705 ENOG4105R3A Nitrate reductase FZN31_RS13710 ENOG4108IUE nitrate reductase beta subunit FZN31_RS13715 ENOG4105CRU nitrate reductase, alpha subunit FZN31_RS13720 ENOG4105DQQ Major facilitator superfamily MFS_1 FZN31_RS13725 ENOG4105BZU Histidine kinase FZN31_RS13730 ENOG4105WH1 Two component transcriptional regulator luxr family FZN31_RS13735 ENOG4105ID0 Putative invasin FZN31_RS13740 ENOG41090EX DsrE family FZN31_RS13745 ENOG4108NH8 Cation transport protein FZN31_RS13750 ENOG4105WS7 Cation transport regulator FZN31_RS13755 ENOG4105EWV Sodium calcium exchanger membrane region FZN31_RS13775 ENOG41063JG Transcriptional regulator FZN31_RS13780 ENOG4108YY7 Invasion gene expression up-regulator SirB FZN31_RS13785 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FZN31_RS13795 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) FZN31_RS13810 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FZN31_RS13815 ENOG4105CHH sulfate transporter FZN31_RS13820 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria FZN31_RS13830 ENOG4105C3G gtp-binding protein FZN31_RS13835 ENOG4105I1J Autotransporter FZN31_RS13840 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FZN31_RS13845 ENOG4105CMT Dihydroxyacetone kinase FZN31_RS13850 ENOG4108UTZ Dihydroxyacetone kinase FZN31_RS13855 ENOG4105VDH Dihydroxyacetone kinase FZN31_RS13870 ENOG4105S10 periplasmic binding protein FZN31_RS13875 ENOG4105EHG Permease protein FZN31_RS13880 ENOG4105E0A ABC, transporter FZN31_RS13885 ENOG4108BSC Methyltransferase FZN31_RS13890 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FZN31_RS13905 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) FZN31_RS13915 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FZN31_RS13935 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FZN31_RS13945 ENOG4105ED1 spovr family FZN31_RS13960 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) FZN31_RS13965 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FZN31_RS13970 ENOG4105KT5 UmuD protein FZN31_RS13975 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells FZN31_RS13985 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FZN31_RS13995 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium FZN31_RS14000 ENOG4105S66 prophage protein FZN31_RS14010 ENOG4107QMS site-determining protein FZN31_RS14040 ENOG410658X FZN31_RS14050 ENOG4105BZU Histidine kinase FZN31_RS14055 ENOG410738I uncharacterized protein ymgC FZN31_RS14065 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB FZN31_RS14070 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component FZN31_RS14075 ENOG4105BZU Histidine kinase FZN31_RS14080 ENOG4108XDN Transcriptional regulator FZN31_RS14085 ENOG41064WM Uncharacterized protein YcgX FZN31_RS14100 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FZN31_RS14120 ENOG4108HMX isocitrate dehydrogenase (NADP) FZN31_RS14145 ENOG4107QTF adenylosuccinate lyase FZN31_RS14150 ENOG4105XJC Two component transcriptional regulator (Winged helix family FZN31_RS14155 ENOG4105IFJ Histidine kinase FZN31_RS14160 ENOG4105EZE Cupin 4 family protein FZN31_RS14170 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS14175 ENOG4105F38 ABC transporter, permease FZN31_RS14180 ENOG4105D38 putrescine abc transporter FZN31_RS14185 ENOG4107RUE extracellular solute-binding protein family 1 FZN31_RS14190 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FZN31_RS14200 ENOG4105D60 lipoprotein releasing system transmembrane protein FZN31_RS14205 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FZN31_RS14210 ENOG4105D60 lipoprotein releasing system transmembrane protein FZN31_RS14215 ENOG4105IQC Inner membrane protein YcfT FZN31_RS14220 ENOG4108JA2 transcriptioN-repair coupling factor FZN31_RS14225 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FZN31_RS14230 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction FZN31_RS14235 ENOG4108IND Tetr family transcriptional regulator FZN31_RS14240 ENOG4107MBR 17 kDa surface antigen FZN31_RS14245 ENOG4105CEP NADH dehydrogenase FZN31_RS14265 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) FZN31_RS14270 ENOG41090DQ Lipoprotein FZN31_RS14275 ENOG4105K59 histidine triad (HIT) protein FZN31_RS14280 ENOG4105CNM Receptor FZN31_RS14285 ENOG4105CI1 PTS System FZN31_RS14290 ENOG4105F8V Hydrolase, tatD family FZN31_RS14295 ENOG4107QRG dna polymerase iii FZN31_RS14305 ENOG4105HHA aminodeoxychorismate lyase FZN31_RS14310 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FZN31_RS14315 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FZN31_RS14320 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FZN31_RS14325 ENOG4105CHR reductase FZN31_RS14330 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FZN31_RS14350 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FZN31_RS14355 ENOG4108UHJ MAF-like protein FZN31_RS14360 ENOG4105EI2 Pseudouridine synthase FZN31_RS14365 ENOG4107QQB Ribonuclease E FZN31_RS14370 ENOG4105DTJ flagellar hook-associated protein FZN31_RS14375 ENOG4105E1Q flagellar hook-associated protein FZN31_RS14380 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FZN31_RS14395 ENOG4105CGA flagellar basal-body rod protein FlgG FZN31_RS14400 ENOG4108KPB Flagellar basal-body rod protein FlgF FZN31_RS14405 ENOG4105BZE flagellar hook protein, FlgE FZN31_RS14410 ENOG4105W00 Flagellar hook capping protein FZN31_RS14415 ENOG4108ZC9 flagellar basal-body rod protein flgc FZN31_RS14420 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FZN31_RS14425 ENOG4105CKS Flagella basal body P-ring formation protein flgA FZN31_RS14430 ENOG4105M9M anti-sigma28 factor FlgM FZN31_RS14435 ENOG4105QVD Flagella synthesis protein FlgN FZN31_RS14440 ENOG4105CJR Integral membrane protein (MviN FZN31_RS14445 ENOG4105EP9 oxidoreductase FZN31_RS14455 ENOG4105D9U N-acetyltransferase FZN31_RS14465 ENOG4105E9S glutaredoxin 2 FZN31_RS14470 ENOG4105F3T (LipO)protein FZN31_RS14480 ENOG4105MEA DNA damage-inducible protein i FZN31_RS14485 ENOG4105PVA Biofilm formation regulatory protein BssS FZN31_RS14495 ENOG4106974 biofilm formation FZN31_RS14500 ENOG4105DS1 cytochrome b561 FZN31_RS14505 ENOG4108YYC ycei family FZN31_RS14515 ENOG4105D1S lipid A biosynthesis FZN31_RS14525 ENOG4108W47 Acidic protein msyB FZN31_RS14530 ENOG4105NAC (LipO)protein FZN31_RS14535 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) FZN31_RS14550 ENOG4107RZC phospholipase d FZN31_RS14555 ENOG4108UVJ appr-1-p processing domain protein FZN31_RS14570 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin FZN31_RS14575 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers FZN31_RS14580 ENOG41086KC Transcriptional regulator FZN31_RS14585 ENOG4108XDW curli assembly protein CsgE FZN31_RS14590 ENOG4108WYR Curli production assembly transport component, CsgF FZN31_RS14595 ENOG4105P8Q Curli production assembly transport component CsgG FZN31_RS14600 ENOG4108UQ5 membrane protein YcdZ FZN31_RS14605 ENOG4107XHZ cytoplasmic chaperone TorD family protein FZN31_RS14615 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase FZN31_RS14625 ENOG4105BZU Histidine kinase FZN31_RS14630 ENOG4108TUY outer membrane protein PgaA FZN31_RS14635 ENOG4107BJW polysaccharide deacetylase FZN31_RS14640 ENOG4105CND Glycosyl transferase, family 2 FZN31_RS14645 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD FZN31_RS14650 ENOG4105D5M phosphate starvation-inducible protein FZN31_RS14655 ENOG4105DBE peroxidase FZN31_RS14660 ENOG410650H (LipO)protein FZN31_RS14665 ENOG4105EKT )-iron permease FZN31_RS14670 ENOG4105CK7 Sodium proline symporter FZN31_RS14680 ENOG4105C26 Dehydrogenase FZN31_RS14685 ENOG4108R86 Transcriptional regulator FZN31_RS14705 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FZN31_RS14720 ENOG4105C2W permease FZN31_RS14725 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 FZN31_RS14735 ENOG4105XH3 FZN31_RS14740 ENOG4105D6F Phosphatase FZN31_RS14765 ENOG4107QY8 reductase FZN31_RS14770 ENOG4105CUW cytochrome C-TYPE protein FZN31_RS14775 ENOG4106WF9 DNA-binding transcriptional regulator TorR FZN31_RS14780 ENOG4108SV3 Tmao reductase system periplasmic protein tort FZN31_RS14785 ENOG4105BZU Histidine kinase FZN31_RS14790 ENOG4105HEE Binding Domain protein FZN31_RS14795 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation FZN31_RS14810 ENOG4105VEQ Cold shock protein FZN31_RS14815 ENOG41060EU Cold shock-like protein FZN31_RS14825 ENOG4108Y9B (LipO)protein FZN31_RS14830 ENOG4108W78 Pfam:DUF1017 FZN31_RS14835 ENOG4105E3R (LipO)protein FZN31_RS14840 ENOG4105DAY polysaccharide export protein FZN31_RS14845 ENOG4107ZF2 Phosphatase FZN31_RS14855 ENOG4105D6F Phosphatase FZN31_RS14865 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FZN31_RS14870 ENOG4105C4M (Ubiquinol oxidase) subunit I FZN31_RS14875 ENOG4105MVP hydrogenase-1 operon protein HyaF FZN31_RS14880 ENOG4108VXY Hydrogenase-1 operon protein HyaE FZN31_RS14885 ENOG4108USZ hydrogenase FZN31_RS14890 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit FZN31_RS14895 ENOG4105DPX Hydrogenase, large subunit FZN31_RS14900 ENOG4105E3S small subunit FZN31_RS14910 ENOG4105UZW Tail fiber assembly protein FZN31_RS14915 ENOG4108X9F tail fiber protein FZN31_RS14985 ENOG4105IM0 capsid protein FZN31_RS14995 ENOG4105F7J membrane-bound serine protease FZN31_RS15005 ENOG4107DE1 head-to-tail joining protein FZN31_RS15010 ENOG4105UZW Tail fiber assembly protein FZN31_RS15015 ENOG4105FKG DNA packaging protein FZN31_RS15075 ENOG4105KSK (crossover) junction endodeoxyribonuclease FZN31_RS15080 ENOG4108MXB Protein of unknown function (DUF968) FZN31_RS15100 ENOG4105WI6 cell killing protein encoded within cryptic prophage FZN31_RS15125 ENOG4105YQ0 FZN31_RS15160 ENOG4106G8A Qin prophage FZN31_RS15180 ENOG4108MN8 Membrane FZN31_RS15185 ENOG4108Z0T Part of a sulfur-relay system (By similarity) FZN31_RS15190 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FZN31_RS15205 ENOG4105K4P CoA-binding domain protein FZN31_RS15220 ENOG41088T4 Helicase IV FZN31_RS15225 ENOG410901E Membrane FZN31_RS15230 ENOG4105EM2 membrane FZN31_RS15235 ENOG4108RZ1 DNA transformation protein FZN31_RS15245 ENOG4105UYK outer membrane protein a FZN31_RS15255 ENOG4105DAN ATP-dependent protease FZN31_RS15265 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) FZN31_RS15270 ENOG4108Q2G (LipO)protein FZN31_RS15275 ENOG4105DY2 Paraquat-inducible protein b FZN31_RS15280 ENOG4105F1S paraquat-inducible protein a FZN31_RS15285 ENOG4105C5H ABC transporter FZN31_RS15290 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FZN31_RS15295 ENOG4105QVC MOSC domain-containing protein FZN31_RS15300 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) FZN31_RS15310 ENOG4108UZX fmn reductase FZN31_RS15315 ENOG4105GVF (ABC) transporter FZN31_RS15325 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FZN31_RS15335 ENOG4105CD8 aminopeptidase N FZN31_RS15350 ENOG4105FCK Membrane FZN31_RS15355 ENOG4105CGF Aromatic amino acid aminotransferase FZN31_RS15360 ENOG4105C5X domain protein FZN31_RS15365 ENOG4105EAQ (twin-arginine translocation) pathway signal FZN31_RS15370 ENOG4105DIT ErfK YbiS YcfS YnhG family protein FZN31_RS15375 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) FZN31_RS15380 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) FZN31_RS15390 ENOG4106371 Methyltransferase FZN31_RS15395 ENOG4107S90 membrAne FZN31_RS15400 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups FZN31_RS15415 ENOG4105T0Z Conserved Protein FZN31_RS15420 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) FZN31_RS15425 ENOG4105BZ1 (ABC) transporter FZN31_RS15430 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 FZN31_RS15440 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FZN31_RS15450 ENOG4108K0D peptidase, M48 FZN31_RS15465 ENOG4107VMU Membrane FZN31_RS15470 ENOG4105DDY UPF0142 protein ycaO FZN31_RS15475 ENOG4105TMB Formate nitrite transporter FZN31_RS15480 ENOG4105C6N Formate acetyltransferase FZN31_RS15485 ENOG4105F1A Pyruvate formate-lyase FZN31_RS15490 ENOG4108X0B nad(p)h dehydrogenase (quinone) FZN31_RS15495 ENOG410642W LysR family Transcriptional regulator FZN31_RS15500 ENOG4105E5D amino acid FZN31_RS15510 ENOG4105CHJ isochorismatase hydrolase FZN31_RS15515 ENOG4107KGK dmso reductase anchor subunit FZN31_RS15520 ENOG4105QAX Iron-sulfur FZN31_RS15525 ENOG4107QY8 reductase FZN31_RS15535 ENOG4105D1H recombination factor protein RarA FZN31_RS15545 ENOG4105CNU cell division protein FtsK FZN31_RS15550 ENOG4105EW9 transcriptional regulator AsnC family FZN31_RS15555 ENOG4105C3M thioredoxin reductase FZN31_RS15560 ENOG4108JJ9 ABC, transporter FZN31_RS15565 ENOG4108JJ8 (ABC) transporter FZN31_RS15575 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FZN31_RS15585 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FZN31_RS15595 ENOG4105VEQ Cold shock protein FZN31_RS15600 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FZN31_RS15605 ENOG4105DJY efflux transporter, rnd family, mfp subunit FZN31_RS15610 ENOG4108MJ5 VirK protein FZN31_RS15615 ENOG4105CPB ATP-dependent endonuclease of the OLD family FZN31_RS15620 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FZN31_RS15625 ENOG4105DWU Membrane FZN31_RS15635 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FZN31_RS15640 ENOG4105C7K acetolactate synthase FZN31_RS15645 ENOG4105C5W Aldolase FZN31_RS15650 ENOG4105CGD Nad-dependent epimerase dehydratase FZN31_RS15655 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FZN31_RS15660 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FZN31_RS15675 ENOG41064MM (LipO)protein FZN31_RS15680 ENOG4105E5Z arginine transporter ATP-binding subunit FZN31_RS15685 ENOG4106PMH Extracellular solute-binding protein family 3 FZN31_RS15690 ENOG4105GBT ABC transporter FZN31_RS15695 ENOG4105DMR ABC, transporter FZN31_RS15700 ENOG4106TNF Periplasmic binding protein FZN31_RS15710 ENOG4105RBQ inner membrane protein ybjO FZN31_RS15715 ENOG4105D38 putrescine abc transporter FZN31_RS15720 ENOG4105F38 ABC transporter, permease FZN31_RS15725 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS15730 ENOG4107RUE extracellular solute-binding protein family 1 FZN31_RS15735 ENOG4108RMJ sensory transduction regulator FZN31_RS15745 ENOG4108DBC nitroreductase FZN31_RS15750 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress FZN31_RS15755 ENOG41090BQ Glutaredoxin FZN31_RS15760 ENOG4105GWF inner membrane protein YbjM FZN31_RS15770 ENOG4108RFG Tetr family transcriptional regulator FZN31_RS15775 ENOG4106UW1 Major Facilitator superfamily FZN31_RS15780 ENOG4108HCJ Hydrolase FZN31_RS15790 ENOG4107QF7 multi-drug FZN31_RS15795 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FZN31_RS15800 ENOG4107FB0 transcriptional regulator DeoR family FZN31_RS15805 ENOG4105DZ1 carboxypeptidase FZN31_RS15810 ENOG4108TGY Glutathione S-transferase FZN31_RS15815 ENOG4105D8V Glucose sorbosone dehydrogenase FZN31_RS15820 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway FZN31_RS15830 ENOG41064RH membrane protein YliF FZN31_RS15835 ENOG4105BZU Histidine kinase FZN31_RS15840 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FZN31_RS15850 ENOG4105DEF Extracellular solute-binding protein, family 5 FZN31_RS15855 ENOG4108JQ6 ABC transporter FZN31_RS15860 ENOG4105D44 asparaginase FZN31_RS15865 ENOG4105CVM Molybdenum cofactor synthesis domain protein FZN31_RS15870 ENOG4105D06 uba thif-type nad fad binding protein FZN31_RS15875 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FZN31_RS15880 ENOG4105F1A Pyruvate formate-lyase FZN31_RS15885 ENOG4105C6N Formate acetyltransferase FZN31_RS15890 ENOG4108HCJ Hydrolase FZN31_RS15895 ENOG41072TH Protein of unknown function (DUF1479) FZN31_RS15900 ENOG4105C5H ABC transporter FZN31_RS15905 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FZN31_RS15910 ENOG4105F4P )-transporter FZN31_RS15915 ENOG4105KST dependent repressor FZN31_RS15945 ENOG4105UZW Tail fiber assembly protein FZN31_RS15950 ENOG4108X9F tail fiber protein FZN31_RS16045 ENOG4105ED4 portal protein FZN31_RS16055 ENOG4105VZ1 Replication Protein FZN31_RS16065 ENOG4105DFE Dna adenine methylase FZN31_RS16095 ENOG4105MEH FZN31_RS16105 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FZN31_RS16120 ENOG4108I6E Sulfatase FZN31_RS16125 ENOG4108T1M outer membrane protein x FZN31_RS16135 ENOG4107AQZ Membrane FZN31_RS16145 ENOG4107R0W ABC transporter FZN31_RS16150 ENOG4105E5Q amino acid AbC transporter FZN31_RS16155 ENOG4105CDA abc transporter atp-binding protein FZN31_RS16160 ENOG4105D8X mechanosensitive ion channel FZN31_RS16170 ENOG4105ZY9 UPF0379 protein ybiM FZN31_RS16175 ENOG4108IU3 tonb-dependent siderophore receptor FZN31_RS16185 ENOG4105KSC Transcriptional regulator, TraR DksA family FZN31_RS16190 ENOG4105VR4 UPF0379 protein ybiJ FZN31_RS16195 ENOG4105DG4 malate L-lactate dehydrogenase FZN31_RS16200 ENOG4108MTB glycosyl transferase family FZN31_RS16205 ENOG4105DVT helicase FZN31_RS16220 ENOG4105C1J atp-dependent rna helicase FZN31_RS16225 ENOG4107MVR Transcriptional regulator FZN31_RS16235 ENOG4105CJ1 ABC, transporter FZN31_RS16240 ENOG4107QWP ABC-2 type transporter FZN31_RS16245 ENOG4107QWP ABC-2 type transporter FZN31_RS16250 ENOG4105I9U inner membrane protein ybhQ FZN31_RS16255 ENOG4105X23 Endonuclease Exonuclease phosphatase FZN31_RS16260 ENOG4105DZQ phospholipase D Transphosphatidylase FZN31_RS16265 ENOG4107UXM Membrane FZN31_RS16285 ENOG4105HFZ Membrane FZN31_RS16290 ENOG4108ZAF Molybdopterin FZN31_RS16295 ENOG4105M00 molybdopterin converting factor, subunit 1 FZN31_RS16305 ENOG4108RIR Molybdenum cofactor biosynthesis protein FZN31_RS16315 ENOG4105CHW UPF0052 protein FZN31_RS16335 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FZN31_RS16340 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FZN31_RS16355 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FZN31_RS16360 ENOG4108V1U phospholipid-binding protein FZN31_RS16365 ENOG4105NBR Pectinesterase FZN31_RS16370 ENOG4107QM5 aconitate hydratase FZN31_RS16375 ENOG4107QPK )-transporter FZN31_RS16380 ENOG4105C7F AcnD-accessory protein PrpF FZN31_RS16385 ENOG4105F04 LysR family Transcriptional regulator FZN31_RS16395 ENOG4108K4B hydrolase FZN31_RS16400 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS16405 ENOG4105E0C molybdate abc transporter FZN31_RS16410 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FZN31_RS16415 ENOG410680R Protein of unknown function (DUF2592) FZN31_RS16420 ENOG4105F4R Transcriptional regulator mode FZN31_RS16425 ENOG4105DKW ABC transporter FZN31_RS16430 ENOG4105CMR udp-glucose 4-epimerase FZN31_RS16435 ENOG4105F0Z galactose-1-phosphate uridylyltransferase FZN31_RS16445 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FZN31_RS16455 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FZN31_RS16460 ENOG4105JND homeobox protein FZN31_RS16465 ENOG4105PGM cation diffusion facilitator family transporter FZN31_RS16470 ENOG4106Z1T Nicotinamide Mononucleotide Transporter FZN31_RS16520 ENOG4105UFD tol-pal system protein YbgF FZN31_RS16525 ENOG4105KCK Peptidoglycan-associated lipoprotein FZN31_RS16535 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA FZN31_RS16540 ENOG4105M8F Biopolymer transport protein exbD tolR FZN31_RS16545 ENOG4105E02 MotA TolQ exbB proton channel FZN31_RS16550 ENOG4107YD3 Thioesterase FZN31_RS16555 ENOG4105KJB cyd operon protein YbgE FZN31_RS16565 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FZN31_RS16570 ENOG4105C4M (Ubiquinol oxidase) subunit I FZN31_RS16585 ENOG4107WFU Glutamate mutase subunit sigma FZN31_RS16595 ENOG4105DJI Methylaspartate mutase, E subunit FZN31_RS16620 ENOG4107GFK fumarate FZN31_RS16625 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase FZN31_RS16630 ENOG4105ETT transcriptional Regulator, LysR family FZN31_RS16635 ENOG4105C84 Histidine ammonia-lyase FZN31_RS16645 ENOG4105CI2 imidazolone-5-propionate hydrolase FZN31_RS16650 ENOG41090B9 response to stress FZN31_RS16655 ENOG4105ETS cytosine purines uracil thiamine allantoin FZN31_RS16660 ENOG4105CGP Urocanate hydratase FZN31_RS16670 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FZN31_RS16680 ENOG4105C7S Dehydrogenase FZN31_RS16685 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FZN31_RS16690 ENOG4105E33 succinate dehydrogenase FZN31_RS16695 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FZN31_RS16700 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FZN31_RS16705 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FZN31_RS16715 ENOG4105BZN citrate synthase FZN31_RS16720 ENOG4106UBK fimbrial-like adhesin protein FZN31_RS16725 ENOG4106PG1 outer membrane usher protein FZN31_RS16730 ENOG4108TTM chaperone FZN31_RS16735 ENOG4108MY7 Fimbrial FZN31_RS16740 ENOG4108KK1 membrane protein AbrB duplication FZN31_RS16755 ENOG4107R7A Allophanate hydrolase subunit 2 FZN31_RS16760 ENOG4105P4J Allophanate hydrolase, subunit 1 FZN31_RS16765 ENOG4107QNR UPF0135 protein FZN31_RS16770 ENOG4105DUX Transporter FZN31_RS16775 ENOG4105CVP deoxyribo-dipyrimidine photolyase FZN31_RS16780 ENOG4107SEY Conserved Protein FZN31_RS16805 ENOG4105XIQ Protein of unknown function (DUF2517) FZN31_RS16825 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) FZN31_RS16830 ENOG4105C08 Histidine kinase FZN31_RS16835 ENOG4105EEX Two component transcriptional regulator (Winged helix family FZN31_RS16845 ENOG4105CXN decarboxylase FZN31_RS16850 ENOG4105D5Q Arginine ornithine antiporter FZN31_RS16870 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 FZN31_RS16875 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) FZN31_RS16880 ENOG4105EV9 Alpha Beta Hydrolase FZN31_RS16885 ENOG4105NNH LexA regulated protein FZN31_RS16890 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) FZN31_RS16900 ENOG41090R7 Ferric uptake FZN31_RS16905 ENOG4105GX6 (LipO)protein FZN31_RS16920 ENOG4105CI1 PTS System FZN31_RS16930 ENOG4105CE4 GlcNAc 6-P deacetylase FZN31_RS16935 ENOG4105E2R ROK family FZN31_RS16940 ENOG4105D4U had-superfamily hydrolase, subfamily iia FZN31_RS16945 ENOG4105CAQ asparagine synthetase FZN31_RS16990 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FZN31_RS17000 ENOG4105C9A Phoh family FZN31_RS17010 ENOG4108JU5 Magnesium and cobalt efflux protein FZN31_RS17015 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FZN31_RS17020 ENOG4107RP9 extracellular solute-binding protein, family 3 FZN31_RS17025 ENOG4105EAD ABC transporter FZN31_RS17030 ENOG4105DRP amino acid AbC transporter FZN31_RS17035 ENOG4105CDA abc transporter atp-binding protein FZN31_RS17045 ENOG4105F7F Chaperone FZN31_RS17050 ENOG4105QFC Hsc56 co-chaperone of HscC FZN31_RS17055 ENOG41069CF Protein of unknown function (DUF1266) FZN31_RS17060 ENOG4107JFD Sel1 repeat FZN31_RS17065 ENOG4105QFC Hsc56 co-chaperone of HscC FZN31_RS17070 ENOG41069CF Protein of unknown function (DUF1266) FZN31_RS17075 ENOG4105EUU Sel1 domain protein repeat-containing protein FZN31_RS17080 ENOG4107PAI alpha helical protein FZN31_RS17095 ENOG4105DJF DNA polymerase III, delta' subunit FZN31_RS17105 ENOG4108TGR phosphatase FZN31_RS17110 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) FZN31_RS17120 ENOG4105CJN penicillin-binding protein FZN31_RS17125 ENOG4105CNI cell division protein FtsW FZN31_RS17130 ENOG4105K6T rare lipoprotein A FZN31_RS17135 ENOG4105DZ1 carboxypeptidase FZN31_RS17150 ENOG41064T2 transcriptional regulator, lysR family FZN31_RS17160 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) FZN31_RS17165 ENOG4107QPI nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FZN31_RS17175 ENOG4105VEQ Cold shock protein FZN31_RS17180 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) FZN31_RS17185 ENOG4105CEE C4-dicarboxylate transporter FZN31_RS17190 ENOG4106YYS transcriptional regulatory protein FZN31_RS17195 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FZN31_RS17200 ENOG4105DUA (citrate (pro-3S)-lyase ligase FZN31_RS17210 ENOG4105CI0 Citrate lyase FZN31_RS17215 ENOG4105CHY citrate lyase, alpha FZN31_RS17230 ENOG4107QPK )-transporter FZN31_RS17235 ENOG4105KTS ribonuclease FZN31_RS17240 ENOG4105NXH GreA GreB family elongation factor FZN31_RS17245 ENOG4108U51 Universal stress protein FZN31_RS17250 ENOG4108JU3 Alkyl hydroperoxide reductase FZN31_RS17255 ENOG4105D3R alkyl hydroperoxide reductase FZN31_RS17260 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase FZN31_RS17265 ENOG4105DQS Transcriptional regulator FZN31_RS17270 ENOG4105BZV Phosphoadenosine phosphosulfate reductase FZN31_RS17275 ENOG4105GTN ParB Domain Protein Nuclease FZN31_RS17280 ENOG4105CHM Aminotransferase FZN31_RS17285 ENOG4107SCQ Iron-containing alcohol dehydrogenase FZN31_RS17290 ENOG4105VCD cytoplasmic protein FZN31_RS17295 ENOG4105D22 carbon starvation protein FZN31_RS17305 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) FZN31_RS17310 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FZN31_RS17315 ENOG4105WQI isochorismatase FZN31_RS17320 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FZN31_RS17325 ENOG4105E4F Isochorismate synthase FZN31_RS17330 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein FZN31_RS17340 ENOG4105DQ5 transport system permease protein FZN31_RS17345 ENOG4105TVJ transport system, permease FZN31_RS17350 ENOG4105E0A ABC, transporter FZN31_RS17355 ENOG4108QY5 Ferric enterobactin transport protein FZN31_RS17360 ENOG4105C0W non-ribosomal peptide synthetase FZN31_RS17365 ENOG41085A6 mbth domain-containing protein FZN31_RS17370 ENOG4105E93 esterase FZN31_RS17375 ENOG4107RNH Outer membrane receptor FepA FZN31_RS17380 ENOG4108TSE Transferase FZN31_RS17385 ENOG4107635 Hok Gef family protein FZN31_RS17390 ENOG4107635 Hok Gef family protein FZN31_RS17395 ENOG4107635 Hok Gef family protein FZN31_RS17405 ENOG4105WQ6 Membrane FZN31_RS17410 ENOG4105MSB protein, conserved in bacteria FZN31_RS17415 ENOG4108RCM Nitroreductase FZN31_RS17420 ENOG4105CUY Mechanosensitive ion channel FZN31_RS17425 ENOG4105C85 amino acid FZN31_RS17430 ENOG4108IJF Heavy metal efflux pump, CzcA FZN31_RS17435 ENOG4105EP1 Efflux transporter rnd family, mfp subunit FZN31_RS17440 ENOG410624V efflux system protein FZN31_RS17445 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FZN31_RS17450 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FZN31_RS17455 ENOG4105GR3 Histidine kinase FZN31_RS17460 ENOG410802X bacteriophage n4 adsorption protein b FZN31_RS17465 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit FZN31_RS17470 ENOG4105QUW FZN31_RS17480 ENOG4108NC2 Outer membrane protease FZN31_RS17485 ENOG4108MIW Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions FZN31_RS17495 ENOG4108WF3 methyltransferase FZN31_RS17500 ENOG4105UZW Tail fiber assembly protein FZN31_RS17505 ENOG4108X9F tail fiber protein FZN31_RS17580 ENOG4105IM0 capsid protein FZN31_RS17590 ENOG4105F7J membrane-bound serine protease FZN31_RS17600 ENOG4107DE1 head-to-tail joining protein FZN31_RS17605 ENOG4105UZW Tail fiber assembly protein FZN31_RS17610 ENOG4105FKG DNA packaging protein FZN31_RS17615 ENOG4106YSC FZN31_RS17630 ENOG4105QYK bacteriophage lambda Bor protein homolog FZN31_RS17640 ENOG4105KUS lysozyme FZN31_RS17645 ENOG4105QFS Lysis protein S homolog from lambdoid prophage FZN31_RS17655 ENOG4105HRS Antitermination protein FZN31_RS17670 ENOG4105RWQ Protein of unknown function (DUF1364) FZN31_RS17675 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 FZN31_RS17680 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi FZN31_RS17690 ENOG4108UQN AraC family transcriptional regulator FZN31_RS17695 ENOG4108V1U phospholipid-binding protein FZN31_RS17700 ENOG4107TII Recombinase FZN31_RS17710 ENOG410814C multidrug resistance protein FZN31_RS17800 ENOG4108KU3 Integrase FZN31_RS17810 ENOG4108Q9V regulatoR FZN31_RS17815 ENOG4108ZI2 Fimbrial protein FZN31_RS17820 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) FZN31_RS17825 ENOG4105CW0 outer membrane usher protein FZN31_RS17830 ENOG4108AF8 Chaperone FZN31_RS17835 ENOG4108WDE Fimbrial protein FZN31_RS17845 ENOG4105WQ3 Rna-binding protein FZN31_RS17850 ENOG4105S2T inner membrane protein YbcI FZN31_RS17860 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FZN31_RS17870 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FZN31_RS17875 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FZN31_RS17880 ENOG4105C5B carbamate kinase FZN31_RS17885 ENOG4105G5A Protein of unknown function (DUF2877) FZN31_RS17890 ENOG4107REC cytoplasmic protein FZN31_RS17900 ENOG4105DG4 malate L-lactate dehydrogenase FZN31_RS17905 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FZN31_RS17910 ENOG4105S0E allantoin catabolism protein FZN31_RS17915 ENOG4105BZW Glycerate kinase FZN31_RS17920 ENOG4105DTE Xanthine uracil vitamin C permease FZN31_RS17930 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FZN31_RS17935 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FZN31_RS17940 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FZN31_RS17945 ENOG41060W2 glyoxylate carboligase FZN31_RS17950 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region FZN31_RS17955 ENOG4108Z2U ureidoglycolate hydrolase FZN31_RS17960 ENOG4107653 Transcriptional regulator FZN31_RS17970 ENOG4105CV6 ABC transporter, permease FZN31_RS17975 ENOG4108I0Y (ABC) transporter FZN31_RS17980 ENOG4108UJV acyl-CoA thioesterase i FZN31_RS17985 ENOG4105E1F short-chain dehydrogenase reductase FZN31_RS17990 ENOG4107QR8 Thioredoxin FZN31_RS17995 ENOG4105C4B ABC transporter, permease FZN31_RS18000 ENOG41083J0 (ABC) transporter FZN31_RS18005 ENOG4107QX8 SPFH domain, Band 7 family protein FZN31_RS18010 ENOG4105G5H Membrane FZN31_RS18035 ENOG4108Z6Z Transcriptional regulator FZN31_RS18040 ENOG4107QZV Type I secretion membrane fusion protein FZN31_RS18060 ENOG4107RY6 amino acid FZN31_RS18065 ENOG4105CSV Glutaminase FZN31_RS18070 ENOG4105C59 p-type ATPase FZN31_RS18075 ENOG4105MBR gumn family FZN31_RS18080 ENOG4108Z66 YbaK ebsC protein FZN31_RS18095 ENOG4105CGH 5'-nucleotidase FZN31_RS18100 ENOG4105EU0 Major facilitator Superfamily FZN31_RS18105 ENOG4105CKD glutathione-regulated potassium-efflux system protein FZN31_RS18110 ENOG4107RE1 Inosine-guanosine kinase FZN31_RS18145 ENOG4107QMP dna polymerase iii subunits gamma and tau FZN31_RS18155 ENOG4105WD1 Membrane FZN31_RS18160 ENOG4108URS primosomal replication protein n'' FZN31_RS18165 ENOG4106428 Protein of unknown function (DUF2496) FZN31_RS18170 ENOG4105EGS Mechanosensitive ion channel FZN31_RS18175 ENOG4108IG5 Transcriptional regulator FZN31_RS18180 ENOG4105C1P efflux transporter, rnd family, mfp subunit FZN31_RS18185 ENOG4105BZS acriflavin resistance protein FZN31_RS18190 ENOG4108UKR Biofilm formation regulator YbaJ FZN31_RS18195 ENOG4105KF5 hemolysin expression-modulating protein FZN31_RS18200 ENOG4108UW5 maltose o-acetyltransferase FZN31_RS18205 ENOG4105GSJ Inner membrane protein ylaC FZN31_RS18210 ENOG41066DG (EAL) domain protein FZN31_RS18215 ENOG4105KCV RNA signal recognition particle 4.5S RNA FZN31_RS18225 ENOG41080UX Methyltransferase FZN31_RS18230 ENOG4108MNP Glycoprotein polysaccharide metabolism FZN31_RS18235 ENOG4105C29 acyl-CoA thioesterase FZN31_RS18240 ENOG4105BZU Histidine kinase FZN31_RS18245 ENOG4108YZA Nitrogen regulatory protein pii FZN31_RS18250 ENOG4105BZ1 (ABC) transporter FZN31_RS18255 ENOG4105BZ1 (ABC) transporter FZN31_RS18260 ENOG4108XM1 transcriptional regulator AsnC family FZN31_RS18270 ENOG4108NFA extracellular solute-binding protein FZN31_RS18280 ENOG4108TGP Thioesterase superfamily protein FZN31_RS18285 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FZN31_RS18290 ENOG4105EIN peptidylprolyl cis-trans isomerase FZN31_RS18295 ENOG4105K70 DNA-binding protein FZN31_RS18300 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FZN31_RS18320 ENOG4105M85 Bola protein FZN31_RS18325 ENOG4105IEY (LipO)protein FZN31_RS18330 ENOG4105EYM Major Facilitator superfamily FZN31_RS18335 ENOG4105E2S oxidase) subunit II FZN31_RS18340 ENOG4105BZ9 Cytochrome C oxidase, subunit I FZN31_RS18345 ENOG4105CCU oxidase (Subunit III) FZN31_RS18350 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FZN31_RS18375 ENOG4107RDB Major Facilitator FZN31_RS18385 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FZN31_RS18390 ENOG4107S0N DJ-1 family FZN31_RS18405 ENOG4105CTB Polyprenyl synthetase FZN31_RS18415 ENOG4105CPC Aldo Keto reductase FZN31_RS18420 ENOG4108ZAI phosphatidylglycerophosphatase a FZN31_RS18425 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FZN31_RS18435 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FZN31_RS18440 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FZN31_RS18450 ENOG4108KIC (LipO)protein FZN31_RS18455 ENOG4105DRB nucleoside-specific channel-forming protein FZN31_RS18460 ENOG4105N1F Hnh endonuclease FZN31_RS18465 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FZN31_RS18470 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FZN31_RS18475 ENOG4105VIE preprotein translocase, subunit YajC FZN31_RS18495 ENOG4107R28 alpha amylase, catalytic region FZN31_RS18500 ENOG4105C85 amino acid FZN31_RS18505 ENOG4105CWM branched-chain amino acid transport system II carrier protein FZN31_RS18510 ENOG4105BZU Histidine kinase FZN31_RS18515 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FZN31_RS18520 ENOG4107RH8 nuclease SbcCD subunit D FZN31_RS18525 ENOG4105EYH Exonuclease FZN31_RS18530 ENOG4105F27 Major Facilitator FZN31_RS18535 ENOG4105DKQ ROK family FZN31_RS18560 ENOG4105HBA AroM protein FZN31_RS18565 ENOG4105SS3 FZN31_RS18580 ENOG4105II7 pyrroline-5-carboxylate reductase FZN31_RS18585 ENOG4105BZU Histidine kinase FZN31_RS18590 ENOG4105VIF phosphate starvation-inducible protein FZN31_RS18595 ENOG4105G6Z alkaline phosphatase FZN31_RS18610 ENOG4105CPF Cell wall formation (By similarity) FZN31_RS18615 ENOG4105UNH Membrane FZN31_RS18620 ENOG4105FR5 inner membrane protein YaiY FZN31_RS18625 ENOG4107QS8 (LipO)protein FZN31_RS18630 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 FZN31_RS18635 ENOG4107R6D beta-lactam binding protein AmpH FZN31_RS18640 ENOG4108PNB DNA-binding transcriptional regulator FZN31_RS18650 ENOG4105D52 delta-aminolevulinic acid dehydratase FZN31_RS18655 ENOG4105E2B Taurine dioxygenase FZN31_RS18660 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FZN31_RS18665 ENOG4108ETV ABC transporter FZN31_RS18670 ENOG4106FTQ Taurine ABC transporter, periplasmic FZN31_RS18690 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FZN31_RS18695 ENOG4108SC4 )-transporter FZN31_RS18720 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) FZN31_RS18730 ENOG4108K2P TRANSCRIPTIONal FZN31_RS18735 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein FZN31_RS18745 ENOG4105ETE Transcriptional regulator (LacI family FZN31_RS18750 ENOG4105CNT hydrolase family 2 FZN31_RS18755 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FZN31_RS18760 ENOG4108UW5 maltose o-acetyltransferase FZN31_RS18765 ENOG4105DJ2 Major Facilitator Superfamily FZN31_RS18775 ENOG4107B2H carbonic anhydrase FZN31_RS18780 ENOG4105DND Transcriptional regulator FZN31_RS18785 ENOG4105DZC cytosine deaminase FZN31_RS18790 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin FZN31_RS18795 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FZN31_RS18800 ENOG4105DXD 2-methylcitrate dehydratase FZN31_RS18805 ENOG4105BZN citrate synthase FZN31_RS18810 ENOG4105CR4 methylisocitrate lyase FZN31_RS18815 ENOG4108JU7 Transcriptional regulator FZN31_RS18820 ENOG4105TDT uncharacterized protein yahO FZN31_RS18825 ENOG4105E82 cytochrome subunit of dehydrogenase FZN31_RS18835 ENOG4105DQ4 alcohol dehydrogenase FZN31_RS18840 ENOG4105CNN ABC, transporter FZN31_RS18845 ENOG4105CNN ABC, transporter FZN31_RS18850 ENOG4105C2J ABC transporter FZN31_RS18855 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FZN31_RS18865 ENOG4105DZC cytosine deaminase FZN31_RS18870 ENOG4105C5B carbamate kinase FZN31_RS18880 ENOG4107REC cytoplasmic protein FZN31_RS18885 ENOG4107R1Q Membrane protein FdrA FZN31_RS18890 ENOG4105N16 Protein of unknown function (DUF2877) FZN31_RS18895 ENOG4107SNB ankyrin repeat protein YahD FZN31_RS18900 ENOG4105SZ2 membrAne FZN31_RS18905 ENOG4108NUU Transcriptional regulator FZN31_RS18910 ENOG4105BZU Histidine kinase FZN31_RS18920 ENOG4105C94 Transporter FZN31_RS18935 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) FZN31_RS18945 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FZN31_RS18950 ENOG4107QR9 Iron-sulfur cluster binding protein FZN31_RS18955 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FZN31_RS18960 ENOG4108K01 transcriptional regulator FZN31_RS18965 ENOG4107QN2 dihydrolipoyl dehydrogenase FZN31_RS18970 ENOG41066GK UPF0379 protein ykgI FZN31_RS18975 ENOG4108KBJ Inner membrane protein YkgB FZN31_RS18980 ENOG4105CV8 reductase FZN31_RS19005 ENOG410642W LysR family Transcriptional regulator FZN31_RS19010 ENOG4105ENX hydrolase FZN31_RS19015 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FZN31_RS19025 ENOG4105NRA 50s ribosomal protein l31 type b FZN31_RS19045 ENOG4108GWT fimbrillin MatB FZN31_RS19060 ENOG4106PYX Receptor FZN31_RS19070 ENOG4105PI0 Ferredoxin FZN31_RS19075 ENOG4105R3P Inner membrane protein yagU FZN31_RS19080 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit FZN31_RS19085 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding FZN31_RS19090 ENOG4105C7W Xanthine dehydrogenase FZN31_RS19095 ENOG4107XAN XdhC and CoxI family FZN31_RS19100 ENOG4107RTG Major Facilitator superfamily FZN31_RS19105 ENOG4105ENX hydrolase FZN31_RS19110 ENOG4105EQ2 LysR family Transcriptional regulator FZN31_RS19125 ENOG4105EMU Dehydrogenase FZN31_RS19150 ENOG4105FCK Membrane FZN31_RS19170 ENOG4105CIN aminoacyl-histidine dipeptidase FZN31_RS19175 ENOG4108S2Y peptide Chain Release factor FZN31_RS19185 ENOG4108HYG acetyltransferase FZN31_RS19215 ENOG4108YS0 lipoprotein YafL FZN31_RS19225 ENOG4105VXN addiction module toxin, RelE StbE family FZN31_RS19230 ENOG4105F7V ErfK ybiS ycfS ynhG family protein FZN31_RS19235 ENOG4105E7A Glutamine amidotransferase FZN31_RS19245 ENOG4107QPN acyl-Coa dehydrogenase FZN31_RS19250 ENOG4108WN0 inhibitor of vertebrate lysozyme FZN31_RS19255 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FZN31_RS19270 ENOG4105CNA YD repeat protein FZN31_RS19275 ENOG4107S17 Phosphate-binding protein FZN31_RS19285 ENOG4105CNA YD repeat protein FZN31_RS19290 ENOG4105CS6 Rhs element vgr protein FZN31_RS19295 ENOG4108WC9 type VI secretion system effector, hcp1 family FZN31_RS19350 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FZN31_RS19375 ENOG4105GMB type VI secretion system effector, hcp1 family FZN31_RS19390 ENOG410600K aminopeptidase FZN31_RS19400 ENOG4107RZZ dna polymerase iii epsilon subunit FZN31_RS19410 ENOG4105D1A Methyltransferase FZN31_RS19415 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FZN31_RS19420 ENOG4105E9H Lytic Murein transglycosylase FZN31_RS19425 ENOG4105F2W methyltransferase FZN31_RS19435 ENOG4105HEI LysR family (Transcriptional regulator FZN31_RS19440 ENOG4105CV8 reductase FZN31_RS19475 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FZN31_RS19480 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS19485 ENOG4108UMI ABC transporter, permease FZN31_RS19490 ENOG4105D01 (LipO)protein FZN31_RS19495 ENOG4108R8X outer membrane lipoprotein FZN31_RS19500 ENOG4108R96 Methyltransferase, YaeB family FZN31_RS19510 ENOG4108UY0 (LipO)protein FZN31_RS19515 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion FZN31_RS19520 ENOG4108YZN class I peptide chain release factor FZN31_RS19525 ENOG4108VWS Yaeq family FZN31_RS19535 ENOG4105M1T rho-binding antiterminator FZN31_RS19540 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FZN31_RS19545 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FZN31_RS19550 ENOG4105CXN decarboxylase FZN31_RS19560 ENOG4105C0B DNA polymerase III (alpha subunit) FZN31_RS19565 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FZN31_RS19585 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FZN31_RS19590 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) FZN31_RS19600 ENOG4105DZP Membrane-associated zinc metalloprotease FZN31_RS19605 ENOG4105KNE Phosphatidate cytidylyltransferase FZN31_RS19610 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FZN31_RS19615 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FZN31_RS19640 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FZN31_RS19660 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR FZN31_RS19665 ENOG4105C0H protease FZN31_RS19680 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) FZN31_RS19685 ENOG4105EN6 Membrane FZN31_RS19710 ENOG4105S6R Iron-hydroxamate transporter permease subunit FZN31_RS19715 ENOG4105J76 Periplasmic binding protein FZN31_RS19720 ENOG4105E0A ABC, transporter FZN31_RS19725 ENOG4105E0K tonB-dependent siderophore receptor FZN31_RS19730 ENOG4105BZ4 penicillin-binding protein FZN31_RS19735 ENOG4105CQ7 ATP-dependent helicase FZN31_RS19740 ENOG4107XID 2'-5' rna ligase FZN31_RS19750 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FZN31_RS19760 ENOG4105DJ0 Poly(A) Polymerase FZN31_RS19765 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FZN31_RS19775 ENOG4108VEV chaperone FZN31_RS19780 ENOG4105CW0 outer membrane usher protein FZN31_RS19785 ENOG4108XEY fimbrial-like adhesin protein FZN31_RS19800 ENOG4105P0Q fimbrial-like protein YadC FZN31_RS19815 ENOG4108A32 Transposase FZN31_RS19825 ENOG4107BJW polysaccharide deacetylase FZN31_RS19830 ENOG4108YTN IIa component FZN31_RS19835 ENOG4105E3A (ABC) transporter FZN31_RS19840 ENOG4105DA5 (ABC) transporter FZN31_RS19845 ENOG41077A9 carbonic anhydrase FZN31_RS19850 ENOG4108UGV hypoxanthine phosphoribosyltransferase FZN31_RS19855 ENOG4105DZG Dehydrogenase FZN31_RS19860 ENOG4105E3B Multicopper oxidase FZN31_RS19865 ENOG4108ZRK uncharacterized protein yacC FZN31_RS19885 ENOG4107QIJ Aconitate hydratase 2 FZN31_RS19890 ENOG4108NST exported protein FZN31_RS19895 ENOG4107QN2 dihydrolipoyl dehydrogenase FZN31_RS19900 ENOG4107QSN dihydrolipoamide acetyltransferase FZN31_RS19905 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FZN31_RS19910 ENOG41073TP transcriptional regulator FZN31_RS19915 ENOG4105C85 amino acid FZN31_RS19920 ENOG4106A72 regulatory protein AmpE FZN31_RS19925 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FZN31_RS19930 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FZN31_RS19935 ENOG4108ZUW Major pilin subunit FZN31_RS19940 ENOG4107QHF type ii secretion system protein e FZN31_RS19945 ENOG4105D7Q type ii secretion system FZN31_RS19955 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FZN31_RS19965 ENOG41067SF Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) FZN31_RS19970 ENOG4105M6F mutator MutT protein FZN31_RS19990 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FZN31_RS19995 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FZN31_RS20000 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FZN31_RS20005 ENOG4105CPF Cell wall formation (By similarity) FZN31_RS20020 ENOG4105CNI cell division protein FtsW FZN31_RS20025 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FZN31_RS20035 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FZN31_RS20040 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FZN31_RS20045 ENOG4105CJN penicillin-binding protein FZN31_RS20050 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FZN31_RS20065 ENOG4107B7Y DNA-binding transcriptional regulator FruR FZN31_RS20075 ENOG4108ZP8 Acetolactate synthase small subunit FZN31_RS20080 ENOG4105C7K acetolactate synthase FZN31_RS20085 ENOG41064T2 transcriptional regulator, lysR family FZN31_RS20125 ENOG4105DP9 ABC transporter FZN31_RS20130 ENOG4106SMU thiamine transporter membrane protein FZN31_RS20140 ENOG4108KF1 Membrane FZN31_RS20145 ENOG41063TF transcriptional regulator (AraC FZN31_RS20160 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FZN31_RS20180 ENOG4105CQ2 DNA polymerase FZN31_RS20190 ENOG4105D3G Pseudouridine synthase FZN31_RS20205 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) FZN31_RS20210 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FZN31_RS20215 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FZN31_RS20250 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FZN31_RS20265 ENOG4105M5B (LipO)protein FZN31_RS20270 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FZN31_RS20275 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FZN31_RS20300 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FZN31_RS20305 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FZN31_RS20315 ENOG4105DTN riboflavin biosynthesis protein ribF FZN31_RS20320 ENOG410647N response to DNA damage stimulus FZN31_RS20355 ENOG41063Z6 transcriptional regulator, lysR family FZN31_RS20370 ENOG41061MV Arylsulfatase FZN31_RS20380 ENOG4105WI6 cell killing protein encoded within cryptic prophage FZN31_RS20400 ENOG4108QUJ UPF0174 protein YaaW FZN31_RS20405 ENOG4106HK8 GPR1 FUN34 yaaH family protein FZN31_RS20410 ENOG4108RIR Molybdenum cofactor biosynthesis protein FZN31_RS20415 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FZN31_RS20420 ENOG4105BZG amino acid carrier protein FZN31_RS20430 ENOG41062C6 Protein of unknown function (DUF2502) FZN31_RS20435 ENOG4105D98 threonine synthase FZN31_RS20445 ENOG4105CFH Aspartokinase FZN31_RS20455 ENOG4106FVC RNA methyltransferase FZN31_RS20460 ENOG410759A FZN31_RS20465 ENOG41065U4 response regulator FZN31_RS20470 ENOG4105CT7 inner membrane cred family protein FZN31_RS20475 ENOG4105EB3 Histidine kinase FZN31_RS20480 ENOG4105E3W Two component transcriptional regulator (Winged helix family FZN31_RS20485 ENOG4108RH0 Crea protein FZN31_RS20490 ENOG4105UEI Transcriptional Regulator AraC Family FZN31_RS20500 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FZN31_RS20510 ENOG4107SC1 transglycosylase FZN31_RS20515 ENOG4105C5H ABC transporter FZN31_RS20525 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system FZN31_RS20530 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase FZN31_RS20535 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FZN31_RS20540 ENOG4105EAC phosphoserine phosphatase FZN31_RS20545 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) FZN31_RS20580 ENOG4105G0K glycine radical enzyme YjjI family FZN31_RS20585 ENOG41076CZ activating enzyme FZN31_RS20590 ENOG4105EYA deoxyribonuclease FZN31_RS20595 ENOG4108NRW Phospholipase, patatin family FZN31_RS20605 ENOG4105K3G Periplasmic Protein FZN31_RS20615 ENOG4105PAD Hydrolase FZN31_RS20620 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FZN31_RS20625 ENOG4108WPU DNA polymerase III subunit psi FZN31_RS20630 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) FZN31_RS20650 ENOG4105YBH Protein of unknown function (DUF1435) FZN31_RS20655 ENOG4108819 ferric iron reductase FZN31_RS20660 ENOG4108T94 DNA-binding transcriptional activator BglJ FZN31_RS20665 ENOG4108N8T regulatoR FZN31_RS20670 ENOG4105DWK Membrane FZN31_RS20685 ENOG4106CVF DNA replication protein FZN31_RS20690 ENOG4105RI1 glycoprotein receptor FZN31_RS20700 ENOG4105CPQ Dehydrogenase FZN31_RS20705 ENOG410617M Transcriptional regulator FZN31_RS20710 ENOG4108I5G Major Facilitator superfamily FZN31_RS20715 ENOG4105C8Q Methyl-accepting chemotaxis FZN31_RS20725 ENOG4108IA2 Sodium pantothenate symporter FZN31_RS20745 ENOG4105D22 carbon starvation protein FZN31_RS20750 ENOG4105VCD cytoplasmic protein FZN31_RS20755 ENOG4105CKI cobalamin synthesis protein FZN31_RS20775 ENOG4108F3G Type I restriction-modification system, R subunit FZN31_RS20785 ENOG4107QTH restriction modification system DNA specificity domain FZN31_RS20805 ENOG4106DIZ Domain of unknown function (DUF1127) FZN31_RS20810 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FZN31_RS20820 ENOG41083G8 Multidrug resistance protein MdtM FZN31_RS20825 ENOG4106BRA Membrane FZN31_RS20830 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FZN31_RS20835 ENOG4105CIZ coA-substrate-specific enzyme activase FZN31_RS20850 ENOG4108ZK4 sdia-regulated domain-containing protein FZN31_RS20855 ENOG4105CBP Major Facilitator FZN31_RS20860 ENOG4105TNG K13735 adhesin invasin FZN31_RS20870 ENOG41074DU domain protein FZN31_RS20875 ENOG4108P2H Inner membrane protein YjiG FZN31_RS20880 ENOG4105DYB Isoaspartyl dipeptidase FZN31_RS20885 ENOG4107YNJ LysR family Transcriptional regulator FZN31_RS20905 ENOG4105C6F GntR Family Transcriptional Regulator FZN31_RS20910 ENOG4105DEI Mannitol dehydrogenase FZN31_RS20920 ENOG4107EFN gluconate transport system permease 3 FZN31_RS20925 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin FZN31_RS20930 ENOG4108T65 Fimbrial FZN31_RS20935 ENOG4108SQA Fimbrial FZN31_RS20940 ENOG4105CW0 outer membrane usher protein FZN31_RS20945 ENOG4108NAE Fimbrial chaperone protein FZN31_RS20950 ENOG4108S54 Fimbrial protein FZN31_RS20960 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off FZN31_RS20965 ENOG4108W9T type 1 fimbriae regulatory protein FZN31_RS20970 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria FZN31_RS20975 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) FZN31_RS20995 ENOG4105C4R Atp-dependent dna helicase FZN31_RS21000 ENOG4108I5C dEAD DEAH box helicase FZN31_RS21010 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FZN31_RS21040 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) FZN31_RS21045 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) FZN31_RS21075 ENOG4105DQ4 alcohol dehydrogenase FZN31_RS21080 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FZN31_RS21085 ENOG4105CPQ Dehydrogenase FZN31_RS21090 ENOG4105CHR reductase FZN31_RS21095 ENOG4105C6Z Gluconate FZN31_RS21100 ENOG4105K2J Transcriptional regulator FZN31_RS21105 ENOG4105D7A ATP-binding protein FZN31_RS21110 ENOG4108K5H permease YjgP YjgQ family protein FZN31_RS21115 ENOG4108M8S permease YjgP YjgQ family protein FZN31_RS21125 ENOG4105MYG DNA polymerase iii, chi subunit FZN31_RS21130 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FZN31_RS21135 ENOG4108M3P Membrane FZN31_RS21140 ENOG4108MJ3 acetyltransferase FZN31_RS21145 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) FZN31_RS21160 ENOG4105XEP YhcH YjgK YiaL family protein FZN31_RS21165 ENOG4108XFH Transcriptional regulator FZN31_RS21170 ENOG4105F6U Short-chain dehydrogenase reductase Sdr FZN31_RS21175 ENOG4108UQ8 endoribonuclease L-psp FZN31_RS21180 ENOG41077AM PyrBI operon attenuator FZN31_RS21195 ENOG4105KME endoribonuclease L-psp FZN31_RS21205 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FZN31_RS21215 ENOG4105D4X repressor FZN31_RS21220 ENOG4105C5Y PTS System FZN31_RS21225 ENOG4105CG3 alpha amylase, catalytic region FZN31_RS21230 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FZN31_RS21235 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FZN31_RS21245 ENOG4108XVM Cytochrome b(562) FZN31_RS21250 ENOG4105CMS peptidase U62, modulator of DNA gyrase FZN31_RS21255 ENOG4105N42 UPF0307 protein FZN31_RS21260 ENOG4105DFU Cell wall formation (By similarity) FZN31_RS21270 ENOG41062B0 ABC transporter, permease FZN31_RS21275 ENOG4107R9N ABC transporter FZN31_RS21280 ENOG4105C2J ABC transporter FZN31_RS21285 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator FZN31_RS21290 ENOG4105F0N pyrophosphate phospho-hydrolase FZN31_RS21295 ENOG4108ZHD aig2 family FZN31_RS21300 ENOG4105MA0 exported protein FZN31_RS21305 ENOG4105CFU surface antigen FZN31_RS21315 ENOG4105C37 (CBS) domain FZN31_RS21320 ENOG41061GZ Protein of unknown function (DUF1107) FZN31_RS21325 ENOG4108UUE Transcriptional regulator FZN31_RS21335 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FZN31_RS21340 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic FZN31_RS21345 ENOG4105KVH Transcriptional regulator FZN31_RS21350 ENOG4105ECR NmrA family FZN31_RS21355 ENOG4105DXC membrane FZN31_RS21365 ENOG4105C85 amino acid FZN31_RS21370 ENOG4108V1T peptidylprolyl cis-trans isomerase FZN31_RS21375 ENOG4105FHY Opacity-associated protein A FZN31_RS21385 ENOG4105CHR reductase FZN31_RS21395 ENOG4105E39 Enoyl-CoA hydratase FZN31_RS21400 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FZN31_RS21405 ENOG4107S3R L-aspartate oxidase FZN31_RS21410 ENOG4105DPW Major facilitator superfamily MFS_1 FZN31_RS21425 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FZN31_RS21440 ENOG4105KIT UPF0379 protein yjfY FZN31_RS21465 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport FZN31_RS21470 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FZN31_RS21485 ENOG4108MXZ Esterase FZN31_RS21490 ENOG4105WSB biofilm stress and motility protein A FZN31_RS21495 ENOG4105S17 UPF0379 protein yjfN FZN31_RS21500 ENOG4105CSU acyl-Coa dehydrogenase FZN31_RS21505 ENOG4106032 Glutathionylspermidine synthase FZN31_RS21510 ENOG4108KXT Conserved Protein FZN31_RS21515 ENOG4105Z6B inner membrane protein yjfl FZN31_RS21520 ENOG4107VNS Protein of unknown function (DUF2491) FZN31_RS21530 ENOG4108P9J Phage shock protein A FZN31_RS21535 ENOG4105FUX Conserved Protein FZN31_RS21540 ENOG4105C2N RNA methyltransferase TrmH family group 3 FZN31_RS21545 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FZN31_RS21565 ENOG4105EPW hflc protein FZN31_RS21570 ENOG4107QJR hflk protein FZN31_RS21575 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FZN31_RS21580 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FZN31_RS21595 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FZN31_RS21600 ENOG4105K8N protein family UPF0079, ATPase FZN31_RS21605 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FZN31_RS21610 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FZN31_RS21650 ENOG4105EGS Mechanosensitive ion channel FZN31_RS21655 ENOG4106CG8 Inner membrane protein YjeO FZN31_RS21660 ENOG4107SC7 Inner membrane transporter yjeM FZN31_RS21670 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) FZN31_RS21675 ENOG4105E33 succinate dehydrogenase FZN31_RS21690 ENOG41066YJ Beta-lactamase FZN31_RS21695 ENOG4105QNF Outer membrane lipoprotein FZN31_RS21700 ENOG4105KPY Small multidrug resistance protein FZN31_RS21705 ENOG4106BSU Entericidin B FZN31_RS21710 ENOG4106HKS Entericidin EcnA/B family FZN31_RS21720 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FZN31_RS21725 ENOG4105MTB Uncharacterized protein YjeJ FZN31_RS21730 ENOG4108ZVF (LipO)protein FZN31_RS21745 ENOG4105DVH amino acid FZN31_RS21750 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 FZN31_RS21755 ENOG4108IJ0 Aspartate ammonia-lyase FZN31_RS21760 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FZN31_RS21770 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FZN31_RS21775 ENOG4108SIC Transcriptional regulator FZN31_RS21785 ENOG4108M3R transcriptional activator CadC FZN31_RS21790 ENOG4105D5Q Arginine ornithine antiporter FZN31_RS21795 ENOG4105CXN decarboxylase FZN31_RS21800 ENOG4105DUX Transporter FZN31_RS21805 ENOG4105CRK lysyL-tRNA synthetase FZN31_RS21820 ENOG410830R acetyltransferase FZN31_RS21825 ENOG4105VR1 Pfam:DUF1271 FZN31_RS21830 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FZN31_RS21835 ENOG4108MRH transcriptional regulatory protein FZN31_RS21840 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FZN31_RS21845 ENOG4107GFK fumarate FZN31_RS21850 ENOG4108R5S membrane FZN31_RS21855 ENOG4105F8D glycoside hydrolase family 4 FZN31_RS21860 ENOG4108K2B transcriptional regulator FZN31_RS21865 ENOG4105CXN decarboxylase FZN31_RS21870 ENOG4106ZGR Transcriptional regulator FZN31_RS21875 ENOG4105D5Q Arginine ornithine antiporter FZN31_RS21880 ENOG4105DIJ Phosphoethanolamine transferase FZN31_RS21885 ENOG4105XJC Two component transcriptional regulator (Winged helix family FZN31_RS21890 ENOG4105ECM Sensor protein basS pmrB FZN31_RS21900 ENOG4105CSH Transporter FZN31_RS21905 ENOG4108YIV FZN31_RS21910 ENOG4108F5E vimentin FZN31_RS21915 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FZN31_RS21920 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase FZN31_RS21930 ENOG4105EHI Phosphonate ABC transporter, periplasmic FZN31_RS21940 ENOG4107RJJ Transcriptional regulator FZN31_RS21945 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG FZN31_RS21950 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH FZN31_RS21955 ENOG4105EKV Phosphonate metabolism protein FZN31_RS21960 ENOG4105FT8 Phosphonate metabolism FZN31_RS21965 ENOG4105ENV phosphonate C-P lyase system protein PhnK FZN31_RS21970 ENOG4105HRV phosphonate c-p lyase system protein phnl FZN31_RS21975 ENOG4105FD8 phosphonate metabolism protein PhnM FZN31_RS21985 ENOG410849A acetyltransferase, (GNAT) family FZN31_RS21990 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein FZN31_RS21995 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 FZN31_RS22000 ENOG4108YZG isomerase FZN31_RS22005 ENOG4105EUZ Beta-lactamase domain protein FZN31_RS22010 ENOG4106833 FZN31_RS22015 ENOG4105J12 Multidrug resistance protein mdtN FZN31_RS22020 ENOG4108MI0 Resistance protein FZN31_RS22025 ENOG4105ETP RND efflux system, outer membrane lipoprotein FZN31_RS22035 ENOG41082ND Uncharacterized protein yjcO FZN31_RS22040 ENOG4105CK2 sodium dicarboxylate symporter FZN31_RS22045 ENOG4108W0S formate-dependent nitrite reductase complex FZN31_RS22055 ENOG4108QKW cytochrome c-type biogenesis protein FZN31_RS22060 ENOG4105DVI reductase, NrfD FZN31_RS22065 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FZN31_RS22070 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit FZN31_RS22080 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FZN31_RS22085 ENOG41062QD Membrane FZN31_RS22100 ENOG4105EEQ Na H antiporter FZN31_RS22105 ENOG4105C7N Xanthine uracil vitamin C permease FZN31_RS22110 ENOG4108Z4X TRANSCRIPTIONal FZN31_RS22115 ENOG4108W3Q Transcriptional regulator FZN31_RS22120 ENOG4108M8H domain protein FZN31_RS22125 ENOG4105PMV Membrane FZN31_RS22130 ENOG4105TW1 Carbohydrate-selective porin OprB FZN31_RS22135 ENOG41079KZ Major Facilitator Superfamily FZN31_RS22140 ENOG4105ETE Transcriptional regulator (LacI family FZN31_RS22145 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FZN31_RS22150 ENOG4105ERH Fumarylacetoacetate hydrolase FZN31_RS22155 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FZN31_RS22160 ENOG4108UUM single-stranded DNA-binding protein FZN31_RS22165 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FZN31_RS22170 ENOG4105MSB protein, conserved in bacteria FZN31_RS22175 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FZN31_RS22180 ENOG4105F0S class B acid phosphatase FZN31_RS22185 ENOG4105CGF Aromatic amino acid aminotransferase FZN31_RS22190 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FZN31_RS22195 ENOG4105CDU Replicative dna helicase FZN31_RS22200 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FZN31_RS22205 ENOG4105P4Z Phage shock protein G FZN31_RS22210 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FZN31_RS22220 ENOG4105MYN Zinc uptake regulation protein FZN31_RS22225 ENOG4105VDW Csbd family FZN31_RS22230 ENOG4107R73 Mate efflux family protein FZN31_RS22240 ENOG41080IJ Diacylglycerol kinase FZN31_RS22265 ENOG4107W52 maltose operon periplasmic protein FZN31_RS22275 ENOG4108IJ9 (ABC) transporter FZN31_RS22280 ENOG4107FKK extracellular solute-binding protein family 1 FZN31_RS22285 ENOG4105D56 permease protein FZN31_RS22290 ENOG4105EG2 ABC transporter, permease FZN31_RS22300 ENOG4105E3R (LipO)protein FZN31_RS22305 ENOG4108Q9C Periplasmic Protein FZN31_RS22310 ENOG4108MDC (LipO)protein FZN31_RS22325 ENOG4105CFH Aspartokinase FZN31_RS22330 ENOG4108ZR5 Conserved Protein FZN31_RS22335 ENOG4105FE9 pseudouridine synthase FZN31_RS22345 ENOG4105EAM Na Pi-cotransporter FZN31_RS22350 ENOG4105C3R Methionine synthase FZN31_RS22355 ENOG41069M3 Transcriptional regulator FZN31_RS22370 ENOG4108I9X Isocitrate lyase FZN31_RS22375 ENOG4107QP3 malate synthase g FZN31_RS22385 ENOG4105K5X acetyltransferase FZN31_RS22390 ENOG41062WK cellular response to acidity FZN31_RS22420 ENOG4105C12 Phosphoribosylglycinamide synthetase FZN31_RS22425 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FZN31_RS22430 ENOG4105BZU Histidine kinase FZN31_RS22435 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism FZN31_RS22440 ENOG4108T8B Protein of unknown function (DUF1481) FZN31_RS22445 ENOG4105K70 DNA-binding protein FZN31_RS22450 ENOG4105R2J Conserved Protein FZN31_RS22485 ENOG4105D06 uba thif-type nad fad binding protein FZN31_RS22490 ENOG4105WHD thiamine biosynthesis protein ThiS FZN31_RS22500 ENOG4105D41 biosynthesis protein thiH FZN31_RS22535 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FZN31_RS22540 ENOG4105PM1 preprotein translocase subunit SecE FZN31_RS22575 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase FZN31_RS22580 ENOG4105D4A Cell wall formation (By similarity) FZN31_RS22610 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FZN31_RS22620 ENOG4108Y73 Membrane FZN31_RS22625 ENOG4105EJ2 Transcriptional regulator FZN31_RS22635 ENOG4105C5Q Transcriptional regulator FZN31_RS22640 ENOG4108I5G Major Facilitator superfamily FZN31_RS22645 ENOG4105CXK mandelate racemase muconate lactonizing FZN31_RS22650 ENOG4105CMG Carbohydrate kinase FZN31_RS22655 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase FZN31_RS22660 ENOG4105F5R ABC transporter FZN31_RS22665 ENOG4105CNN ABC, transporter FZN31_RS22670 ENOG4105C2J ABC transporter FZN31_RS22680 ENOG4105E98 transcriptional regulator DeoR family FZN31_RS22685 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FZN31_RS22695 ENOG4105CAS nag kinase FZN31_RS22700 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FZN31_RS22715 ENOG4105DIJ Phosphoethanolamine transferase FZN31_RS22720 ENOG4106R3P AraC family transcriptional regulator FZN31_RS22725 ENOG4108XCZ PTS System FZN31_RS22730 ENOG4108AHH pyruvate formate lyase II activase FZN31_RS22735 ENOG4105C6N Formate acetyltransferase FZN31_RS22740 ENOG4108YRF PTS System FZN31_RS22745 ENOG4105DM4 PTS System FZN31_RS22750 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FZN31_RS22755 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FZN31_RS22760 ENOG4105DCT glycerol dehydrogenase FZN31_RS22765 ENOG4108XC3 NADH ubiquinone oxidoreductase FZN31_RS22770 ENOG4108Q5Y Membrane FZN31_RS22780 ENOG4105SYT Methylenetetrahydrofolate reductase FZN31_RS22785 ENOG4105CGH 5'-nucleotidase FZN31_RS22795 ENOG4105CGH 5'-nucleotidase FZN31_RS22800 ENOG4105CGH 5'-nucleotidase FZN31_RS22805 ENOG4105DRB nucleoside-specific channel-forming protein FZN31_RS22810 ENOG4105CFH Aspartokinase FZN31_RS22815 ENOG4105C28 cystathionine FZN31_RS22825 ENOG4107S01 Repressor protein MetJ FZN31_RS22840 ENOG4105CNA YD repeat protein FZN31_RS22850 ENOG4105C25 Primosomal protein n' FZN31_RS22855 ENOG4105ETE Transcriptional regulator (LacI family FZN31_RS22860 ENOG41063M6 Cell Division Protein FZN31_RS22875 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FZN31_RS22895 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FZN31_RS22905 ENOG4105CBT Fructose-1,6-bisphosphatase FZN31_RS22910 ENOG4105DP0 ferredoxin-NADP reductase FZN31_RS22920 ENOG41065TG regulatoR FZN31_RS22925 ENOG4108VTS Membrane FZN31_RS22930 ENOG4105EBK exported protein FZN31_RS22945 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FZN31_RS22960 ENOG4105FMW periplasmic FZN31_RS22965 ENOG4105E3W Two component transcriptional regulator (Winged helix family FZN31_RS22970 ENOG4105E0F Histidine kinase FZN31_RS22975 ENOG4108RPX mosc domain containing protein FZN31_RS22985 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FZN31_RS22995 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) FZN31_RS23030 ENOG41064BA PTS system, fructose-specific, IIA component FZN31_RS23035 ENOG4105DM4 PTS System FZN31_RS23040 ENOG4105CN9 Peptidase m42 family protein FZN31_RS23045 ENOG4106C3V frv operon regulatory protein FZN31_RS23050 ENOG4108V87 frv operon regulatory protein FZN31_RS23065 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein FZN31_RS23070 ENOG4108MG3 formate dehydrogenase FZN31_RS23080 ENOG4106UEE Transcriptional regulator FZN31_RS23090 ENOG4105SUU thioesterase domain FZN31_RS23105 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 FZN31_RS23110 ENOG4105E98 transcriptional regulator DeoR family FZN31_RS23115 ENOG4108MGF sugar kinase FZN31_RS23120 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FZN31_RS23125 ENOG4105D2M Aldolase FZN31_RS23130 ENOG4107QKS N-acylglucosamine 2-epimerase FZN31_RS23135 ENOG4107WI4 Aldose-1-epimerase FZN31_RS23145 ENOG4105CJQ hydrolase, family 31 FZN31_RS23150 ENOG4105CT4 transporter FZN31_RS23155 ENOG4105CT4 transporter FZN31_RS23160 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is FZN31_RS23165 ENOG4105R9B Major Facilitator FZN31_RS23170 ENOG4108KHF Resistance protein FZN31_RS23175 ENOG4108K85 Transcriptional regulator FZN31_RS23185 ENOG4105C5F glutamine synthetase FZN31_RS23190 ENOG4105CUX Signal transduction histidine kinase FZN31_RS23195 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FZN31_RS23200 ENOG4106FIY FZN31_RS23205 ENOG4105D4P Coproporphyrinogen iii oxidase FZN31_RS23225 ENOG4105C2M dna polymerase I FZN31_RS23235 ENOG4106HNH Acyl-transferase FZN31_RS23250 ENOG4105E27 serine threonine protein kinase FZN31_RS23255 ENOG4105PC1 Conserved Protein FZN31_RS23260 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FZN31_RS23265 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b FZN31_RS23295 ENOG4108RR8 protoporphyrinogen oxidase FZN31_RS23300 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FZN31_RS23305 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FZN31_RS23325 ENOG4107QK7 reductase FZN31_RS23330 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FZN31_RS23335 ENOG4105MDZ Transcriptional activator rfaH FZN31_RS23345 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FZN31_RS23350 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) FZN31_RS23355 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FZN31_RS23365 ENOG4105JC1 sterol-binding domain protein FZN31_RS23375 ENOG4105CGY Dna recombination protein FZN31_RS23380 ENOG4107HP6 Transcriptional regulator FZN31_RS23385 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 FZN31_RS23390 ENOG4108RTU Aldolase FZN31_RS23395 ENOG4105JN3 extra-cytoplasmic solute receptor family protein FZN31_RS23410 ENOG4108I5U Uridine phosphorylase FZN31_RS23415 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) FZN31_RS23420 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FZN31_RS23430 ENOG4107R1Q Membrane protein FdrA FZN31_RS23435 ENOG4107REC cytoplasmic protein FZN31_RS23440 ENOG4105C5B carbamate kinase FZN31_RS23450 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin FZN31_RS23455 ENOG4105F52 Transcriptional regulator FZN31_RS23465 ENOG4105DZ2 Transcriptional regulator FZN31_RS23470 ENOG4105EMK carboxylate amino acid amine transporter FZN31_RS23475 ENOG4105DQF Hydrolase FZN31_RS23480 ENOG4108EUD Lysophospholipase FZN31_RS23495 ENOG4105C9U ATP-dependent DNA helicase RecQ FZN31_RS23500 ENOG4105HDD phospholipase FZN31_RS23505 ENOG4108VUY thioesterase Superfamily protein FZN31_RS23510 ENOG4105FR1 rard protein FZN31_RS23525 ENOG4107QUT magnesium and cobalt transport protein CorA FZN31_RS23530 ENOG4108T58 Mg2 transport protein CorA FZN31_RS23535 ENOG4105C4R Atp-dependent dna helicase FZN31_RS23540 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant FZN31_RS23550 ENOG4105CT0 Protein of unknown function, DUF484 FZN31_RS23560 ENOG4105S7Z (LipO)protein FZN31_RS23575 ENOG4107T0K Adenylate cyclase FZN31_RS23580 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FZN31_RS23585 ENOG41076E6 Uroporphyrinogen-III Synthase FZN31_RS23590 ENOG4105ECF c-methyltransferase FZN31_RS23595 ENOG410601J HemY protein FZN31_RS23600 ENOG4105ENH Sulfatase FZN31_RS23605 ENOG4105C4X radical SAM domain protein FZN31_RS23630 ENOG4105C85 amino acid FZN31_RS23645 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) FZN31_RS23650 ENOG4105EGZ biosynthesis protein FZN31_RS23655 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FZN31_RS23660 ENOG4108WJ1 acetyltransferase FZN31_RS23665 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FZN31_RS23670 ENOG4105C1B dTDP-glucose 4-6-dehydratase FZN31_RS23675 ENOG4108IJ1 Dehydrogenase FZN31_RS23680 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FZN31_RS23685 ENOG4105SFE lipopolysaccharide biosynthesis protein FZN31_RS23690 ENOG4105ESV Glycosyl transferase, family 4 FZN31_RS23705 ENOG4105K63 Thioredoxin FZN31_RS23720 ENOG4105C4R Atp-dependent dna helicase FZN31_RS23730 ENOG4105KQ5 peptidylprolyl cis-trans isomerase FZN31_RS23740 ENOG4105EMY transcriptional regulator FZN31_RS23745 ENOG4105C7B Threonine dehydratase FZN31_RS23755 ENOG4105CM2 brancheD-chain amino acid aminotransferase FZN31_RS23760 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit FZN31_RS23780 ENOG4105C0P Mg chelatase subunit ChlI FZN31_RS23785 ENOG4108WFC UPF0438 protein yifE FZN31_RS23825 ENOG4107EJG GntR family transcriptional regulator FZN31_RS23830 ENOG4105C0R drug resistance transporter emrb qaca subfamily FZN31_RS23835 ENOG4105ETE Transcriptional regulator (LacI family FZN31_RS23840 ENOG4108RVA ribokinase FZN31_RS23845 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FZN31_RS23850 ENOG4105CNN ABC, transporter FZN31_RS23855 ENOG4105C2J ABC transporter FZN31_RS23875 ENOG4105EV2 VWA domain protein interacting with AAA ATPase FZN31_RS23880 ENOG4105CU9 asparagine synthetase A FZN31_RS23885 ENOG4108VVK transcriptional Regulator, AsnC FZN31_RS23890 ENOG4105QTB Flavodoxin FZN31_RS23905 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation FZN31_RS23915 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FZN31_RS23960 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FZN31_RS23965 ENOG4108RQP Major type 1 subunit fimbrin FZN31_RS23975 ENOG4105CW0 outer membrane usher protein FZN31_RS23985 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) FZN31_RS23990 ENOG4105C8U phosphate abc transporter FZN31_RS23995 ENOG4105E2Z phosphate ABC transporter (Permease FZN31_RS24000 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FZN31_RS24005 ENOG4108UTW Plays a role in the regulation of phosphate uptake FZN31_RS24025 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 FZN31_RS24030 ENOG4105C7N Xanthine uracil vitamin C permease FZN31_RS24035 ENOG4108YYH Nadph-dependent fmn reductase FZN31_RS24040 ENOG4105E8Q phosphopantetheinyl transferase FZN31_RS24045 ENOG4105G2Y Transcriptional regulator FZN31_RS24055 ENOG4108P6C Tryptophan transporter of low affinity FZN31_RS24105 ENOG4106JVB Replication Protein FZN31_RS24135 ENOG4108YXQ IS66 Orf2 family protein FZN31_RS24175 ENOG4105FR1 rard protein FZN31_RS24185 ENOG4108YXQ IS66 Orf2 family protein FZN31_RS24205 ENOG4106PHM regulatory protein FZN31_RS24225 ENOG4105DWP Membrane FZN31_RS24300 ENOG4108RC6 RTX toxin FZN31_RS24310 ENOG4105EKQ RNA-directed DNA polymerase FZN31_RS24340 ENOG41090WB Transposase is3 is911 FZN31_RS24400 ENOG4106CQM replication FZN31_RS24410 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) FZN31_RS24425 ENOG4105KK6 nuclease FZN31_RS24435 ENOG4107CBI conjugal transfer fertility inhibition protein FZN31_RS24440 ENOG4107U2T alpha beta FZN31_RS24630 ENOG41074AV Hok/gef family FZN31_RS24665 ENOG4105FEQ ParB domain protein nuclease FZN31_RS24720 ENOG4106JQ7 FZN31_RS24725 ENOG41073YN Protein of unknown function (DUF1380) FZN31_RS24750 ENOG4105EKQ RNA-directed DNA polymerase FZN31_RS24810 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) FZN31_RS24815 ENOG4105DUU IucA IucC family protein