locus-tag	class	description
IAI02_RS00010	COG0592	DNA-directed DNA polymerase activity
IAI02_RS00020	COG0187	DNA topoisomerase II activity
IAI02_RS00025	COG3753	Protein conserved in bacteria
IAI02_RS00030	COG0561	phosphatase activity
IAI02_RS00040	COG2186	Transcriptional regulator
IAI02_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
IAI02_RS00050	COG0800	Aldolase
IAI02_RS00085	COG1464	Belongs to the NlpA lipoprotein family
IAI02_RS00090	COG0697	spore germination
IAI02_RS00095	COG2814	Major facilitator Superfamily
IAI02_RS00105	COG2211	Major facilitator Superfamily
IAI02_RS00110	COG1501	Belongs to the glycosyl hydrolase 31 family
IAI02_RS00115	COG2982	Protein involved in outer membrane biogenesis
IAI02_RS00120	COG2233	PERMEase
IAI02_RS00125	COG0786	glutamate:sodium symporter activity
IAI02_RS00130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAI02_RS00135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAI02_RS00140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAI02_RS00150	COG0194	GDP metabolic process
IAI02_RS00160	COG2860	membrane
IAI02_RS00165	COG3645	SOS response
IAI02_RS00170	COG1561	YicC-like family, N-terminal region
IAI02_RS00195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAI02_RS00225	COG1519	Transferase
IAI02_RS00230	COG0859	PFAM glycosyl transferase family 9
IAI02_RS00235	COG0438	transferase activity, transferring glycosyl groups
IAI02_RS00240	COG0515	serine threonine protein kinase
IAI02_RS00255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAI02_RS00265	COG1216	Glycosyl transferase, family 2
IAI02_RS00270	COG3307	-O-antigen
IAI02_RS00275	COG0859	PFAM glycosyl transferase family 9
IAI02_RS00280	COG0859	PFAM glycosyl transferase family 9
IAI02_RS00295	COG0156	8-amino-7-oxononanoate synthase activity
IAI02_RS00305	COG1216	Glycosyl transferase, family 2
IAI02_RS00310	COG2861	carbohydrate metabolic process
IAI02_RS00315	COG4942	peptidase
IAI02_RS00320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAI02_RS00325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAI02_RS00330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAI02_RS00345	COG1045	serine acetyltransferase
IAI02_RS00350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IAI02_RS00360	COG2186	Transcriptional regulator
IAI02_RS00365	COG1620	l-lactate permease
IAI02_RS00380	COG3722	fumarate hydratase activity
IAI02_RS00390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS00390	COG2213	PTS system mannitol-specific
IAI02_RS00400	COG1566	PFAM secretion protein HlyD family protein
IAI02_RS00410	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IAI02_RS00415	COG3209	COG3209 Rhs family protein
IAI02_RS00420	COG0625	glutathione transferase activity
IAI02_RS00430	COG3276	selenocysteine insertion sequence binding
IAI02_RS00435	COG1454	alcohol dehydrogenase
IAI02_RS00440	COG1012	belongs to the aldehyde dehydrogenase family
IAI02_RS00455	COG1566	PFAM secretion protein HlyD family protein
IAI02_RS00460	COG0583	DNA-binding transcription factor activity
IAI02_RS00465	COG3713	MltA-interacting MipA family protein
IAI02_RS00475	COG0235	Class ii aldolase
IAI02_RS00480	COG3623	hexulose-6-phosphate isomerase
IAI02_RS00485	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IAI02_RS00490	COG1070	Carbohydrate kinase
IAI02_RS00495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAI02_RS00500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAI02_RS00505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IAI02_RS00510	COG2731	YhcH YjgK YiaL family protein
IAI02_RS00520	COG1414	Transcriptional regulator
IAI02_RS00525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS00530	COG3977	Valine--pyruvate aminotransferase
IAI02_RS00535	COG0366	Alpha amylase catalytic
IAI02_RS00540	COG2992	FlgJ-related protein
IAI02_RS00545	COG2207	Transcriptional regulator
IAI02_RS00545	COG1609	Transcriptional regulator
IAI02_RS00550	COG4214	carbohydrate transport
IAI02_RS00555	COG1129	ABC transporter
IAI02_RS00560	COG4213	ABC transporter substrate-binding protein
IAI02_RS00570	COG1070	Carbohydrate kinase
IAI02_RS00575	COG4682	membrane
IAI02_RS00580	COG4682	membrane
IAI02_RS00585	COG3274	enterobacterial common antigen metabolic process
IAI02_RS00625	COG1215	transferase activity, transferring glycosyl groups
IAI02_RS00630	COG1215	transferase activity, transferring glycosyl groups
IAI02_RS00635	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IAI02_RS00640	COG3118	belongs to the thioredoxin family
IAI02_RS00640	COG0457	Tetratricopeptide repeat
IAI02_RS00645	COG2200	EAL domain
IAI02_RS00645	COG2199	diguanylate cyclase activity
IAI02_RS00655	COG0612	Peptidase, M16
IAI02_RS00660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS00665	COG2200	EAL domain
IAI02_RS00670	COG2982	Protein involved in outer membrane biogenesis
IAI02_RS00675	COG0477	Major facilitator Superfamily
IAI02_RS00680	COG1295	ribonuclease BN
IAI02_RS00685	COG0583	DNA-binding transcription factor activity
IAI02_RS00690	COG2197	response regulator
IAI02_RS00700	COG1858	cytochrome C peroxidase
IAI02_RS00705	COG0076	glutamate decarboxylase activity
IAI02_RS00710	COG2207	Transcriptional regulator
IAI02_RS00715	COG2207	Transcriptional regulator
IAI02_RS00720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAI02_RS00725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS00735	COG2771	luxR family
IAI02_RS00740	COG3247	response to pH
IAI02_RS00755	COG1285	pathogenesis
IAI02_RS00760	COG2197	response regulator
IAI02_RS00765	COG3065	identical protein binding
IAI02_RS00775	COG1393	Belongs to the ArsC family
IAI02_RS00780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAI02_RS00785	COG0640	Transcriptional regulator
IAI02_RS00795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAI02_RS00800	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IAI02_RS00805	COG0339	signal peptide processing
IAI02_RS00815	COG3104	oligopeptide transport
IAI02_RS00820	COG0589	response to stress
IAI02_RS00830	COG0306	phosphate transporter
IAI02_RS00835	COG2081	HI0933 family
IAI02_RS00855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS00860	COG0842	Transport permease protein
IAI02_RS00860	COG1129	ABC transporter
IAI02_RS00865	COG0842	Transport permease protein
IAI02_RS00870	COG5433	transposase activity
IAI02_RS00875	COG1413	lyase activity
IAI02_RS00885	COG3209	COG3209 Rhs family protein
IAI02_RS00895	COG1124	(ABC) transporter
IAI02_RS00900	COG0444	Belongs to the ABC transporter superfamily
IAI02_RS00905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAI02_RS00910	COG0601	transmembrane transport
IAI02_RS00930	COG2091	lysine biosynthetic process via aminoadipic acid
IAI02_RS00940	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS00945	COG4372	Transposase
IAI02_RS00955	COG3596	GTP binding
IAI02_RS00960	COG2378	regulation of single-species biofilm formation
IAI02_RS01005	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IAI02_RS01010	COG0582	viral genome integration into host DNA
IAI02_RS01015	COG4974	Belongs to the 'phage' integrase family
IAI02_RS01025	COG3539	Fimbrial protein
IAI02_RS01030	COG3121	Chaperone
IAI02_RS01035	COG3188	usher protein
IAI02_RS01040	COG3539	Fimbrial protein
IAI02_RS01045	COG3539	Fimbrial protein
IAI02_RS01050	COG3539	Fimbrial protein
IAI02_RS01055	COG2610	gluconate transmembrane transporter activity
IAI02_RS01065	COG0246	Mannitol dehydrogenase
IAI02_RS01070	COG2186	Transcriptional regulator
IAI02_RS01095	COG0583	DNA-binding transcription factor activity
IAI02_RS01100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAI02_RS01105	COG0700	Nucleoside recognition
IAI02_RS01110	COG3366	ferrous iron transmembrane transporter activity
IAI02_RS01120	COG0477	Major facilitator Superfamily
IAI02_RS01135	COG1924	4 iron, 4 sulfur cluster binding
IAI02_RS01140	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IAI02_RS01145	COG2733	membrane
IAI02_RS01150	COG2814	Major facilitator Superfamily
IAI02_RS01175	COG0523	cobalamin synthesis protein
IAI02_RS01180	COG2879	small protein
IAI02_RS01185	COG1966	Carbon starvation protein
IAI02_RS01190	COG0840	transmembrane signaling receptor activity
IAI02_RS01195	COG2271	Major facilitator Superfamily
IAI02_RS01200	COG1802	Transcriptional regulator
IAI02_RS01205	COG1063	alcohol dehydrogenase
IAI02_RS01220	COG1484	DNA-dependent DNA replication
IAI02_RS01235	COG2966	Psort location CytoplasmicMembrane, score
IAI02_RS01240	COG2197	response regulator
IAI02_RS01245	COG2197	response regulator
IAI02_RS01250	COG4114	ferric iron reductase
IAI02_RS01280	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IAI02_RS01285	COG0456	acetyltransferase
IAI02_RS01290	COG1011	Hydrolase
IAI02_RS01300	COG2823	Periplasmic or secreted lipoprotein
IAI02_RS01310	COG4667	esterase of the alpha-beta hydrolase superfamily
IAI02_RS01315	COG0084	hydrolase, TatD family'
IAI02_RS01320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAI02_RS01325	COG1328	CTP reductase activity
IAI02_RS01350	COG3550	peptidyl-serine autophosphorylation
IAI02_RS01360	COG3726	membrane protein affecting hemolysin expression
IAI02_RS01365	COG0560	Phosphoserine phosphatase
IAI02_RS01370	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAI02_RS01375	COG3172	ATPase kinase involved in NAD metabolism
IAI02_RS01375	COG1056	cytidyltransferase-related domain
IAI02_RS01385	COG0488	(ABC) transporter
IAI02_RS01390	COG0741	lytic transglycosylase activity
IAI02_RS01410	COG3708	Transcriptional regulator
IAI02_RS01410	COG2207	Transcriptional regulator
IAI02_RS01415	COG3045	CreA protein
IAI02_RS01420	COG0745	RESPONSE REGULATOR receiver
IAI02_RS01425	COG2205	protein histidine kinase activity
IAI02_RS01430	COG4452	Inner membrane protein CreD
IAI02_RS01435	COG0745	RESPONSE REGULATOR receiver
IAI02_RS01445	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IAI02_RS01455	COG0460	homoserine dehydrogenase
IAI02_RS01455	COG0527	aspartate kinase activity
IAI02_RS01465	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAI02_RS01480	COG1115	amino acid carrier protein
IAI02_RS01485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAI02_RS01490	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAI02_RS01495	COG1584	GPR1 FUN34 yaaH family protein
IAI02_RS01500	COG4735	regulation of single-species biofilm formation
IAI02_RS01520	COG3385	transposase activity
IAI02_RS01535	COG0583	DNA-binding transcription factor activity
IAI02_RS01560	COG0196	riboflavin kinase activity
IAI02_RS01575	COG1047	Peptidyl-prolyl cis-trans
IAI02_RS01595	COG0505	Belongs to the CarA family
IAI02_RS01600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAI02_RS01650	COG0644	oxidoreductase
IAI02_RS01655	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAI02_RS01660	COG2271	Major facilitator Superfamily
IAI02_RS01690	COG2095	MarC family integral membrane protein
IAI02_RS01695	COG2610	gluconate transmembrane transporter activity
IAI02_RS01700	COG3265	gluconokinase activity
IAI02_RS01705	COG1609	Transcriptional regulator
IAI02_RS01710	COG1741	Belongs to the pirin family
IAI02_RS01715	COG0673	inositol 2-dehydrogenase activity
IAI02_RS01720	COG1247	-acetyltransferase
IAI02_RS01725	COG3157	Type VI secretion system effector, Hcp
IAI02_RS01745	COG0405	Gamma-glutamyltransferase
IAI02_RS01755	COG0584	glycerophosphoryl diester phosphodiesterase
IAI02_RS01760	COG3842	ATPase activity
IAI02_RS01765	COG0395	ABC-type sugar transport system, permease component
IAI02_RS01770	COG1175	transmembrane transport
IAI02_RS01775	COG1653	transport
IAI02_RS01780	COG0410	ABC transporter
IAI02_RS01785	COG0411	ABC transporter
IAI02_RS01790	COG4177	L-phenylalanine transmembrane transporter activity
IAI02_RS01795	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS01800	COG0683	leucine binding
IAI02_RS01805	COG0456	acetyltransferase
IAI02_RS01810	COG0683	leucine binding
IAI02_RS01815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAI02_RS01820	COG2177	Part of the ABC transporter FtsEX involved in
IAI02_RS01825	COG2884	Cell division ATP-binding protein ftsE
IAI02_RS01830	COG0552	protein localization to endoplasmic reticulum
IAI02_RS01835	COG0742	ribosomal rna small subunit methyltransferase
IAI02_RS01840	COG3776	membrane
IAI02_RS01850	COG3714	YhhN family
IAI02_RS01855	COG2217	Heavy metal translocating P-type atpase
IAI02_RS01865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IAI02_RS01875	COG0477	Major facilitator Superfamily
IAI02_RS01880	COG0628	permease
IAI02_RS01885	COG2091	lysine biosynthetic process via aminoadipic acid
IAI02_RS01890	COG0747	negative chemotaxis
IAI02_RS01900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAI02_RS01925	COG0058	SHG alpha-glucan phosphorylase activity
IAI02_RS01935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAI02_RS01950	COG1349	DNA-binding transcription factor activity
IAI02_RS01955	COG4650	regulator
IAI02_RS01960	COG1690	Belongs to the RtcB family
IAI02_RS01975	COG0058	SHG alpha-glucan phosphorylase activity
IAI02_RS01980	COG1640	4-alpha-glucanotransferase
IAI02_RS01985	COG2610	gluconate transmembrane transporter activity
IAI02_RS01995	COG1040	competence protein
IAI02_RS02005	COG5464	transposase or invertase
IAI02_RS02015	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IAI02_RS02020	COG1918	ferrous iron import across plasma membrane
IAI02_RS02025	COG2183	response to ionizing radiation
IAI02_RS02030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAI02_RS02050	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IAI02_RS02060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IAI02_RS02065	COG1011	Hydrolase
IAI02_RS02075	COG0494	nUDIX hydrolase
IAI02_RS02080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IAI02_RS02085	COG4972	Pilus assembly protein
IAI02_RS02090	COG3166	PFAM Fimbrial assembly family protein
IAI02_RS02105	COG4796	Type ii and iii secretion system protein
IAI02_RS02120	COG3266	domain, Protein
IAI02_RS02125	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IAI02_RS02130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAI02_RS02135	COG0546	phosphoglycolate phosphatase activity
IAI02_RS02140	COG0180	Tryptophanyl-tRNA synthetase
IAI02_RS02145	COG2188	Transcriptional regulator
IAI02_RS02155	COG3457	Alanine racemase
IAI02_RS02160	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAI02_RS02165	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IAI02_RS02180	COG0626	cystathionine gamma-synthase activity
IAI02_RS02185	COG2188	Transcriptional regulator
IAI02_RS02190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS02195	COG1082	Xylose isomerase domain protein TIM barrel
IAI02_RS02200	COG2222	sugar isomerase
IAI02_RS02205	COG0531	amino acid
IAI02_RS02220	COG2116	formate transmembrane transporter activity
IAI02_RS02225	COG2146	nitrite reductase [NAD(P)H] activity
IAI02_RS02230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAI02_RS02240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAI02_RS02250	COG2184	nucleotidyltransferase activity
IAI02_RS02255	COG0512	Glutamine amidotransferase of anthranilate synthase
IAI02_RS02260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAI02_RS02265	COG1289	transmembrane transporter activity
IAI02_RS02270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAI02_RS02275	COG1765	OsmC-like protein
IAI02_RS02280	COG3954	Phosphoribulokinase
IAI02_RS02290	COG0429	hydrolase of the alpha beta-hydrolase fold
IAI02_RS02295	COG0488	(ABC) transporter
IAI02_RS02310	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IAI02_RS02315	COG1047	Peptidyl-prolyl cis-trans
IAI02_RS02325	COG0545	Peptidyl-prolyl cis-trans isomerase
IAI02_RS02330	COG2964	Protein conserved in bacteria
IAI02_RS02370	COG3979	chitinase
IAI02_RS02375	COG2906	2 iron, 2 sulfur cluster binding
IAI02_RS02380	COG2193	ferroxidase activity
IAI02_RS02385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IAI02_RS02390	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IAI02_RS02395	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IAI02_RS02400	COG3156	type II secretion system protein K
IAI02_RS02405	COG4795	General secretion pathway protein
IAI02_RS02410	COG2165	general secretion pathway protein
IAI02_RS02415	COG2165	general secretion pathway protein
IAI02_RS02420	COG2165	general secretion pathway protein
IAI02_RS02425	COG1459	type II secretion system
IAI02_RS02430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAI02_RS02435	COG1450	Type ii and iii secretion system protein
IAI02_RS02440	COG3031	protein transport across the cell outer membrane
IAI02_RS02445	COG3409	Peptidoglycan-binding domain 1 protein
IAI02_RS02445	COG3267	Type II secretory pathway component ExeA
IAI02_RS02470	COG0089	rRNA binding
IAI02_RS02560	COG0201	protein transport
IAI02_RS02600	COG0789	Transcriptional regulator
IAI02_RS02605	COG3036	rescue of stalled ribosome
IAI02_RS02615	COG0569	domain protein
IAI02_RS02635	COG0758	DNA mediated transformation
IAI02_RS02645	COG0551	DNA topoisomerase type I activity
IAI02_RS02665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAI02_RS02705	COG1126	abc transporter atp-binding protein
IAI02_RS02710	COG0765	amino acid transport
IAI02_RS02715	COG4597	amino acid ABC transporter
IAI02_RS02720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS02730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAI02_RS02735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS02740	COG1309	transcriptional regulator
IAI02_RS02750	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IAI02_RS02760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAI02_RS02770	COG4145	pantothenate transmembrane transporter activity
IAI02_RS02775	COG3924	membrane
IAI02_RS02780	COG0439	Biotin carboxylase
IAI02_RS02785	COG0511	ligase activity, forming carbon-carbon bonds
IAI02_RS02790	COG0604	alcohol dehydrogenase
IAI02_RS02795	COG2200	EAL domain
IAI02_RS02795	COG2199	diguanylate cyclase activity
IAI02_RS02800	COG1077	Cell shape determining protein MreB Mrl
IAI02_RS02805	COG1792	Involved in formation and maintenance of cell shape
IAI02_RS02810	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IAI02_RS02815	COG0424	maF-like protein
IAI02_RS02820	COG1530	ribonuclease E activity
IAI02_RS02825	COG3164	Protein of unknown function
IAI02_RS02830	COG0312	modulator of DNA gyrase
IAI02_RS02835	COG0583	DNA-binding transcription factor activity
IAI02_RS02855	COG2732	(Barnase) inhibitor
IAI02_RS02875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAI02_RS02880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAI02_RS02885	COG3105	Protein conserved in bacteria
IAI02_RS02890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IAI02_RS02905	COG0625	glutathione transferase activity
IAI02_RS02910	COG2969	positive regulation of protein catabolic process
IAI02_RS02915	COG3069	C4-dicarboxylate transmembrane transporter activity
IAI02_RS02945	COG2731	YhcH YjgK YiaL family protein
IAI02_RS02950	COG4804	nuclease activity
IAI02_RS02960	COG0493	'glutamate synthase
IAI02_RS02965	COG0070	glutamate synthase
IAI02_RS02965	COG0067	glutamate synthase
IAI02_RS02965	COG0069	glutamate synthase activity
IAI02_RS02970	COG1242	4 iron, 4 sulfur cluster binding
IAI02_RS02975	COG5002	protein histidine kinase activity
IAI02_RS02975	COG0784	Response regulator, receiver
IAI02_RS02975	COG2198	Histidine kinase
IAI02_RS02980	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IAI02_RS02990	COG0515	serine threonine protein kinase
IAI02_RS02995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS03010	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAI02_RS03015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IAI02_RS03020	COG1137	ATPase activity
IAI02_RS03025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IAI02_RS03030	COG3117	lipopolysaccharide transmembrane transporter activity
IAI02_RS03035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IAI02_RS03040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IAI02_RS03040	COG0517	IMP dehydrogenase activity
IAI02_RS03045	COG0530	calcium, potassium:sodium antiporter activity
IAI02_RS03050	COG1127	ABC transporter
IAI02_RS03055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IAI02_RS03060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IAI02_RS03065	COG2854	intermembrane phospholipid transfer
IAI02_RS03070	COG3113	response to antibiotic
IAI02_RS03075	COG5007	Belongs to the BolA IbaG family
IAI02_RS03085	COG3423	Transcriptional regulator
IAI02_RS03090	COG0142	geranyltranstransferase activity
IAI02_RS03105	COG0697	spore germination
IAI02_RS03115	COG2027	D-alanyl-D-alanine carboxypeptidase
IAI02_RS03120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAI02_RS03125	COG1534	Rna-binding protein
IAI02_RS03135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAI02_RS03140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAI02_RS03150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAI02_RS03160	COG2194	sulfuric ester hydrolase activity
IAI02_RS03180	COG0195	Participates in both transcription termination and antitermination
IAI02_RS03220	COG0513	Belongs to the DEAD box helicase family
IAI02_RS03225	COG0814	amino acid
IAI02_RS03230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAI02_RS03235	COG0826	peptidase U32
IAI02_RS03240	COG0826	peptidase U32
IAI02_RS03245	COG3154	lipid carrier protein
IAI02_RS03250	COG3153	acetyltransferase
IAI02_RS03265	COG0693	protein deglycase activity
IAI02_RS03270	COG0702	epimerase
IAI02_RS03275	COG0701	Predicted permease
IAI02_RS03280	COG2823	Periplasmic or secreted lipoprotein
IAI02_RS03295	COG3107	peptidoglycan biosynthetic process
IAI02_RS03300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAI02_RS03305	COG3539	Fimbrial protein
IAI02_RS03310	COG3188	usher protein
IAI02_RS03315	COG3121	Chaperone
IAI02_RS03320	COG3539	Fimbrial protein
IAI02_RS03325	COG0363	glucosamine-6-phosphate deaminase activity
IAI02_RS03330	COG3716	PTS system mannose fructose sorbose family IID component
IAI02_RS03335	COG3715	PTS system
IAI02_RS03340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS03350	COG2222	sugar isomerase
IAI02_RS03355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAI02_RS03360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS03365	COG3716	PTS system mannose fructose sorbose family IID component
IAI02_RS03375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS03385	COG1349	DNA-binding transcription factor activity
IAI02_RS03395	COG2002	toxin-antitoxin pair type II binding
IAI02_RS03400	COG2721	sulfolactate sulfo-lyase activity
IAI02_RS03405	COG2271	Major facilitator Superfamily
IAI02_RS03415	COG2084	Dehydrogenase
IAI02_RS03420	COG1929	Belongs to the glycerate kinase type-1 family
IAI02_RS03445	COG0583	DNA-binding transcription factor activity
IAI02_RS03450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAI02_RS03460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAI02_RS03465	COG1882	Formate acetyltransferase
IAI02_RS03470	COG0251	oxidation-reduction process
IAI02_RS03475	COG1760	l-serine dehydratase
IAI02_RS03480	COG0814	amino acid
IAI02_RS03495	COG1741	Belongs to the pirin family
IAI02_RS03500	COG0583	DNA-binding transcription factor activity
IAI02_RS03505	COG3152	Membrane
IAI02_RS03510	COG3152	Membrane
IAI02_RS03515	COG0435	Glutathione S-transferase
IAI02_RS03520	COG2259	Doxx family
IAI02_RS03530	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IAI02_RS03535	COG4575	ribosome binding
IAI02_RS03540	COG1422	Protein of unknown function (DUF1090)
IAI02_RS03550	COG0586	Pfam SNARE associated Golgi protein
IAI02_RS03555	COG2186	Transcriptional regulator
IAI02_RS03560	COG2271	Major facilitator Superfamily
IAI02_RS03570	COG2721	sulfolactate sulfo-lyase activity
IAI02_RS03580	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IAI02_RS03585	COG0861	Integral membrane protein TerC family
IAI02_RS03590	COG0673	inositol 2-dehydrogenase activity
IAI02_RS03595	COG2949	membrane
IAI02_RS03600	COG1451	nucleotide metabolic process
IAI02_RS03610	COG4680	protein conserved in bacteria
IAI02_RS03615	COG5499	transcription regulator containing HTH domain
IAI02_RS03620	COG1902	pentaerythritol trinitrate reductase activity
IAI02_RS03620	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAI02_RS03625	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IAI02_RS03625	COG3408	Glycogen debranching enzyme
IAI02_RS03635	COG0531	amino acid
IAI02_RS03640	COG2731	YhcH YjgK YiaL family protein
IAI02_RS03645	COG3250	beta-galactosidase activity
IAI02_RS03650	COG1609	Transcriptional regulator
IAI02_RS03655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAI02_RS03665	COG0840	transmembrane signaling receptor activity
IAI02_RS03670	COG1695	Transcriptional regulator
IAI02_RS03675	COG2375	cellular response to nickel ion
IAI02_RS03690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAI02_RS03695	COG0358	DNA primase activity
IAI02_RS03700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IAI02_RS03710	COG0471	metal ion transport
IAI02_RS03715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAI02_RS03720	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IAI02_RS03725	COG0583	DNA-binding transcription factor activity
IAI02_RS03735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAI02_RS03750	COG4991	sh3 domain protein
IAI02_RS03755	COG3025	triphosphatase activity
IAI02_RS03780	COG2268	Band 7 protein
IAI02_RS03800	COG3539	Fimbrial protein
IAI02_RS03805	COG2960	long-chain fatty acid transporting porin activity
IAI02_RS03825	COG3384	dioxygenase
IAI02_RS03830	COG0754	glutathionylspermidine amidase activity
IAI02_RS03840	COG1538	Outer membrane efflux protein
IAI02_RS03845	COG0494	nUDIX hydrolase
IAI02_RS03850	COG3151	Protein conserved in bacteria
IAI02_RS03855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAI02_RS03860	COG3150	esterase
IAI02_RS03865	COG0187	DNA topoisomerase II activity
IAI02_RS03870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IAI02_RS03875	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAI02_RS03885	COG0642	Histidine kinase
IAI02_RS03890	COG0745	RESPONSE REGULATOR receiver
IAI02_RS03895	COG3111	PFAM Bacterial OB fold (BOF) protein
IAI02_RS03900	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IAI02_RS03910	COG2944	sequence-specific DNA binding
IAI02_RS03915	COG4166	transmembrane transport
IAI02_RS03920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAI02_RS03925	COG0204	Acyl-transferase
IAI02_RS03930	COG2132	Multicopper oxidase
IAI02_RS03935	COG1032	radical SAM domain protein
IAI02_RS03940	COG4238	major outer membrane lipoprotein
IAI02_RS03950	COG0656	L-ascorbic acid biosynthetic process
IAI02_RS03955	COG1979	alcohol dehydrogenase
IAI02_RS03960	COG2207	Transcriptional regulator
IAI02_RS03965	COG0586	Pfam SNARE associated Golgi protein
IAI02_RS03970	COG0626	cystathionine gamma-synthase activity
IAI02_RS03975	COG0811	peptide transport
IAI02_RS03980	COG0848	biopolymer transport protein
IAI02_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS03995	COG0667	Aldo Keto reductase
IAI02_RS04010	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IAI02_RS04015	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS04020	COG5557	Pfam Polysulphide reductase, NrfD
IAI02_RS04025	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IAI02_RS04030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IAI02_RS04035	COG1773	rubredoxin
IAI02_RS04045	COG0298	carbon dioxide binding
IAI02_RS04050	COG0625	glutathione transferase activity
IAI02_RS04055	COG0754	glutathionylspermidine amidase activity
IAI02_RS04060	COG0306	phosphate transporter
IAI02_RS04065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAI02_RS04070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAI02_RS04075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAI02_RS04080	COG2244	polysaccharide biosynthetic process
IAI02_RS04090	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IAI02_RS04095	COG0795	lipopolysaccharide-transporting ATPase activity
IAI02_RS04105	COG0156	8-amino-7-oxononanoate synthase activity
IAI02_RS04110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAI02_RS04120	COG0318	PFAM AMP-dependent synthetase and ligase
IAI02_RS04125	COG0456	acetyltransferase
IAI02_RS04130	COG2186	Transcriptional regulator
IAI02_RS04135	COG0277	FAD linked oxidase domain protein
IAI02_RS04140	COG0277	FAD linked oxidase domain protein
IAI02_RS04145	COG0247	lactate metabolic process
IAI02_RS04150	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IAI02_RS04155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IAI02_RS04160	COG1620	l-lactate permease
IAI02_RS04190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAI02_RS04195	COG1459	type II secretion system
IAI02_RS04200	COG2165	general secretion pathway protein
IAI02_RS04230	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IAI02_RS04240	COG1811	Na channel or pump
IAI02_RS04245	COG1982	Orn Lys Arg decarboxylase major
IAI02_RS04250	COG2211	Major facilitator Superfamily
IAI02_RS04265	COG1194	a g-specific adenine glycosylase
IAI02_RS04275	COG3171	Protein conserved in bacteria
IAI02_RS04285	COG0252	asparaginase activity
IAI02_RS04295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAI02_RS04300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAI02_RS04310	COG0762	integral membrane protein
IAI02_RS04315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IAI02_RS04320	COG2805	Type II/IV secretion system protein
IAI02_RS04335	COG0189	ligase activity
IAI02_RS04340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAI02_RS04345	COG2356	endonuclease I
IAI02_RS04355	COG2814	Major facilitator Superfamily
IAI02_RS04375	COG1166	arginine decarboxylase activity
IAI02_RS04385	COG0501	Belongs to the peptidase M48B family
IAI02_RS04390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAI02_RS04395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS04400	COG2213	PTS system mannitol-specific
IAI02_RS04405	COG1063	alcohol dehydrogenase
IAI02_RS04410	COG1494	fructose-1,6-bisphosphatase
IAI02_RS04430	COG1072	(Pantothenic acid kinase))
IAI02_RS04445	COG0191	fructose-bisphosphate aldolase activity
IAI02_RS04450	COG0668	transmembrane transport
IAI02_RS04455	COG1279	arginine transmembrane transporter activity
IAI02_RS04460	COG2968	Membrane
IAI02_RS04465	COG0583	DNA-binding transcription factor activity
IAI02_RS04470	COG0427	acetyl-CoA hydrolase
IAI02_RS04475	COG1024	Enoyl-CoA hydratase
IAI02_RS04480	COG1703	isobutyryl-CoA mutase activity
IAI02_RS04485	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAI02_RS04485	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAI02_RS04505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAI02_RS04515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAI02_RS04535	COG0006	proline dipeptidase activity
IAI02_RS04540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAI02_RS04545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAI02_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS04575	COG2723	6-phospho-beta-galactosidase activity
IAI02_RS04585	COG1272	protein, Hemolysin III
IAI02_RS04595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IAI02_RS04605	COG0716	FMN binding
IAI02_RS04610	COG4974	Belongs to the 'phage' integrase family
IAI02_RS04615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAI02_RS04620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAI02_RS04630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IAI02_RS04650	COG2233	PERMEase
IAI02_RS04655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS04655	COG0493	'glutamate synthase
IAI02_RS04660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS04665	COG2252	PERMEase
IAI02_RS04670	COG0402	S-adenosylhomocysteine deaminase activity
IAI02_RS04675	COG2233	PERMEase
IAI02_RS04680	COG2080	2 iron, 2 sulfur cluster binding
IAI02_RS04680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAI02_RS04685	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IAI02_RS04690	COG0402	S-adenosylhomocysteine deaminase activity
IAI02_RS04695	COG0493	'glutamate synthase
IAI02_RS04695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS04700	COG2068	MobA-Related Protein
IAI02_RS04705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAI02_RS04710	COG3608	succinylglutamate desuccinylase aspartoacylase
IAI02_RS04710	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IAI02_RS04715	COG0549	Belongs to the carbamate kinase family
IAI02_RS04725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAI02_RS04730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAI02_RS04735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAI02_RS04740	COG3829	transcription factor binding
IAI02_RS04745	COG2080	2 iron, 2 sulfur cluster binding
IAI02_RS04750	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IAI02_RS04755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAI02_RS04760	COG4942	peptidase
IAI02_RS04865	COG3710	Transcriptional regulator
IAI02_RS04865	COG0457	Tetratricopeptide repeat
IAI02_RS04870	COG0457	Tetratricopeptide repeat
IAI02_RS04895	COG3710	Transcriptional regulator
IAI02_RS04910	COG3039	Transposase
IAI02_RS04915	COG2771	luxR family
IAI02_RS04920	COG0814	amino acid
IAI02_RS04925	COG0183	Belongs to the thiolase family
IAI02_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS04940	COG2814	Major facilitator Superfamily
IAI02_RS04945	COG1794	racemase activity, acting on amino acids and derivatives
IAI02_RS04950	COG0583	DNA-binding transcription factor activity
IAI02_RS04960	COG1609	Transcriptional regulator
IAI02_RS04975	COG0667	Aldo Keto reductase
IAI02_RS04985	COG0861	Integral membrane protein TerC family
IAI02_RS05000	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IAI02_RS05015	COG2165	general secretion pathway protein
IAI02_RS05020	COG4795	General secretion pathway protein
IAI02_RS05030	COG4967	type IV pilus modification protein PilV
IAI02_RS05035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IAI02_RS05040	COG1025	Belongs to the peptidase M16 family
IAI02_RS05045	COG1074	ATP-dependent DNA helicase activity
IAI02_RS05050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAI02_RS05055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAI02_RS05055	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IAI02_RS05060	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAI02_RS05080	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IAI02_RS05085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAI02_RS05090	COG2166	iron-sulfur cluster assembly
IAI02_RS05095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAI02_RS05105	COG0583	DNA-binding transcription factor activity
IAI02_RS05110	COG2363	Small membrane protein
IAI02_RS05120	COG1349	DNA-binding transcription factor activity
IAI02_RS05130	COG1070	Carbohydrate kinase
IAI02_RS05140	COG0738	Major facilitator superfamily
IAI02_RS05145	COG0235	Class ii aldolase
IAI02_RS05150	COG1454	alcohol dehydrogenase
IAI02_RS05160	COG1760	l-serine dehydratase
IAI02_RS05165	COG0814	amino acid
IAI02_RS05170	COG1611	Belongs to the LOG family
IAI02_RS05185	COG3098	single-species biofilm formation
IAI02_RS05190	COG0564	pseudouridine synthase activity
IAI02_RS05195	COG0716	FMN binding
IAI02_RS05200	COG2271	Major facilitator Superfamily
IAI02_RS05205	COG4948	Mandelate Racemase Muconate Lactonizing
IAI02_RS05210	COG4948	Mandelate Racemase Muconate Lactonizing
IAI02_RS05215	COG4999	Histidine kinase
IAI02_RS05215	COG3437	response regulator, receiver
IAI02_RS05215	COG2205	protein histidine kinase activity
IAI02_RS05215	COG3850	Histidine kinase
IAI02_RS05220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAI02_RS05225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAI02_RS05230	COG2336	PFAM SpoVT AbrB
IAI02_RS05235	COG2337	Toxic component of a toxin-antitoxin (TA) module
IAI02_RS05240	COG3956	TIGRFAM MazG family protein
IAI02_RS05255	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IAI02_RS05265	COG0602	queuosine metabolic process
IAI02_RS05270	COG1070	Carbohydrate kinase
IAI02_RS05275	COG2223	nitrite transmembrane transporter activity
IAI02_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS05285	COG0277	FAD linked oxidase domain protein
IAI02_RS05290	COG0477	Major facilitator Superfamily
IAI02_RS05295	COG2086	electron transfer activity
IAI02_RS05300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IAI02_RS05305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IAI02_RS05310	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAI02_RS05320	COG0720	synthase
IAI02_RS05330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAI02_RS05340	COG1203	CRISPR-associated helicase, Cas3
IAI02_RS05355	COG1857	crispr-associated protein
IAI02_RS05370	COG1518	maintenance of DNA repeat elements
IAI02_RS05375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAI02_RS05380	COG2234	aminopeptidase activity
IAI02_RS05435	COG4942	peptidase
IAI02_RS05435	COG1388	LysM domain
IAI02_RS05440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAI02_RS05445	COG2610	gluconate transmembrane transporter activity
IAI02_RS05450	COG3622	Belongs to the hyi family
IAI02_RS05455	COG0235	Class ii aldolase
IAI02_RS05460	COG3395	kinase activity
IAI02_RS05465	COG2084	Dehydrogenase
IAI02_RS05470	COG1349	DNA-binding transcription factor activity
IAI02_RS05475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAI02_RS05495	COG3604	Transcriptional regulator
IAI02_RS05500	COG0309	Hydrogenase expression formation protein (HypE)
IAI02_RS05505	COG0409	Hydrogenase expression formation protein
IAI02_RS05510	COG0298	carbon dioxide binding
IAI02_RS05515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IAI02_RS05520	COG0375	protein maturation
IAI02_RS05530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS05535	COG0651	ATP synthesis coupled electron transport
IAI02_RS05540	COG0650	Formate hydrogenlyase subunit 4
IAI02_RS05545	COG3261	NADH dehydrogenase
IAI02_RS05545	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IAI02_RS05550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAI02_RS05555	COG3260	NADH ubiquinone oxidoreductase 20
IAI02_RS05565	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IAI02_RS05570	COG2723	6-phospho-beta-galactosidase activity
IAI02_RS05575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS05575	COG1263	PTS System
IAI02_RS05580	COG1609	Transcriptional regulator
IAI02_RS05585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS05590	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IAI02_RS05610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IAI02_RS05610	COG0517	IMP dehydrogenase activity
IAI02_RS05615	COG1349	DNA-binding transcription factor activity
IAI02_RS05620	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS05625	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS05630	COG3731	PTS system glucitol sorbitol-specific IIA component
IAI02_RS05635	COG3732	PTS system glucitol sorbitol-specific
IAI02_RS05640	COG3730	PTS system glucitol sorbitol-specific
IAI02_RS05645	COG2951	lytic endotransglycosylase activity
IAI02_RS05650	COG1546	Belongs to the CinA family
IAI02_RS05670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IAI02_RS05700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAI02_RS05705	COG1238	metal cluster binding
IAI02_RS05720	COG2814	Major facilitator Superfamily
IAI02_RS05725	COG1566	PFAM secretion protein HlyD family protein
IAI02_RS05730	COG1846	Transcriptional regulator
IAI02_RS05740	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IAI02_RS05745	COG2814	Major facilitator Superfamily
IAI02_RS05750	COG2113	Glycine betaine
IAI02_RS05755	COG4176	ABC-type proline glycine betaine transport system permease component
IAI02_RS05760	COG4175	Glycine betaine
IAI02_RS05765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAI02_RS05770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAI02_RS05780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAI02_RS05785	COG4575	ribosome binding
IAI02_RS05800	COG2916	Histone family protein nucleoid-structuring protein H-NS
IAI02_RS05805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAI02_RS05810	COG0640	Transcriptional regulator
IAI02_RS05815	COG0401	homolog of Blt101
IAI02_RS05820	COG1652	LysM domain
IAI02_RS05825	COG1802	Transcriptional regulator
IAI02_RS05830	COG1113	amino acid transport
IAI02_RS05835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAI02_RS05840	COG1012	belongs to the aldehyde dehydrogenase family
IAI02_RS05845	COG0579	oxidoreductase
IAI02_RS05860	COG0366	Alpha amylase catalytic
IAI02_RS05880	COG3039	Transposase
IAI02_RS05885	COG4974	Belongs to the 'phage' integrase family
IAI02_RS05920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAI02_RS05950	COG4372	Transposase
IAI02_RS05955	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS06025	COG2867	negative regulation of translational initiation
IAI02_RS06035	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAI02_RS06040	COG0497	DNA recombination
IAI02_RS06055	COG4536	flavin adenine dinucleotide binding
IAI02_RS06060	COG4137	Cytochrome C assembly protein
IAI02_RS06065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAI02_RS06090	COG2885	chlorophyll binding
IAI02_RS06095	COG2199	diguanylate cyclase activity
IAI02_RS06110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAI02_RS06115	COG0287	Prephenate dehydrogenase
IAI02_RS06115	COG1605	Chorismate mutase
IAI02_RS06120	COG1605	Chorismate mutase
IAI02_RS06120	COG0077	Prephenate dehydratase
IAI02_RS06130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAI02_RS06135	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAI02_RS06140	COG0564	pseudouridine synthase activity
IAI02_RS06145	COG1496	oxidoreductase activity
IAI02_RS06150	COG0542	response to heat
IAI02_RS06175	COG0477	Major facilitator Superfamily
IAI02_RS06180	COG5544	Lipoprotein
IAI02_RS06185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAI02_RS06190	COG1042	CoA-binding domain protein
IAI02_RS06190	COG0045	succinate-CoA ligase (ADP-forming) activity
IAI02_RS06190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAI02_RS06195	COG3148	PFAM DTW domain containing protein
IAI02_RS06200	COG3118	belongs to the thioredoxin family
IAI02_RS06205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAI02_RS06225	COG0583	DNA-binding transcription factor activity
IAI02_RS06230	COG0513	Belongs to the DEAD box helicase family
IAI02_RS06240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IAI02_RS06250	COG1595	DNA-templated transcription, initiation
IAI02_RS06255	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IAI02_RS06260	COG3026	antisigma factor binding
IAI02_RS06265	COG3086	response to oxidative stress
IAI02_RS06275	COG0681	Belongs to the peptidase S26 family
IAI02_RS06295	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IAI02_RS06310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS06315	COG1737	Transcriptional regulator
IAI02_RS06320	COG0560	Phosphoserine phosphatase
IAI02_RS06340	COG2205	protein histidine kinase activity
IAI02_RS06345	COG3170	Tfp pilus assembly protein FimV
IAI02_RS06350	COG2204	response regulator
IAI02_RS06355	COG0347	Belongs to the P(II) protein family
IAI02_RS06360	COG1017	nitric oxide dioxygenase activity
IAI02_RS06360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAI02_RS06370	COG1940	carbohydrate kinase activity
IAI02_RS06375	COG0457	Tetratricopeptide repeat
IAI02_RS06380	COG1879	ABC-type sugar transport system periplasmic component
IAI02_RS06385	COG1129	ABC transporter
IAI02_RS06390	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS06395	COG1063	alcohol dehydrogenase
IAI02_RS06400	COG2017	converts alpha-aldose to the beta-anomer
IAI02_RS06405	COG2259	Doxx family
IAI02_RS06430	COG4638	Rieske (2fe-2S)
IAI02_RS06435	COG0583	DNA-binding transcription factor activity
IAI02_RS06440	COG2814	Major facilitator Superfamily
IAI02_RS06445	COG3711	transcriptional antiterminator
IAI02_RS06450	COG1073	alpha beta
IAI02_RS06455	COG0483	inositol monophosphate 1-phosphatase activity
IAI02_RS06475	COG0822	iron-sulfur transferase activity
IAI02_RS06495	COG0633	Ferredoxin
IAI02_RS06500	COG2975	iron-sulfur cluster assembly
IAI02_RS06515	COG2897	thiosulfate sulfurtransferase activity
IAI02_RS06520	COG2373	Large extracellular alpha-helical protein
IAI02_RS06525	COG4953	penicillin-binding protein 1C
IAI02_RS06555	COG2976	Protein conserved in bacteria
IAI02_RS06570	COG1645	bacterial-type flagellum-dependent swarming motility
IAI02_RS06580	COG0517	IMP dehydrogenase activity
IAI02_RS06580	COG0516	GMP reductase activity
IAI02_RS06595	COG3133	Outer membrane lipoprotein
IAI02_RS06625	COG0248	Ppx GppA phosphatase
IAI02_RS06630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IAI02_RS06635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAI02_RS06650	COG2233	PERMEase
IAI02_RS06660	COG1393	Belongs to the ArsC family
IAI02_RS06665	COG4783	chaperone-mediated protein folding
IAI02_RS06670	COG0628	permease
IAI02_RS06680	COG3604	Transcriptional regulator
IAI02_RS06690	COG3260	NADH ubiquinone oxidoreductase 20
IAI02_RS06695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAI02_RS06700	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IAI02_RS06700	COG3261	NADH dehydrogenase
IAI02_RS06710	COG4237	Hydrogenase 4 membrane
IAI02_RS06715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAI02_RS06720	COG0650	Formate hydrogenlyase subunit 4
IAI02_RS06730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS06735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAI02_RS06740	COG2716	regulation of RNA biosynthetic process
IAI02_RS06750	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IAI02_RS06760	COG2321	neutral zinc metallopeptidase
IAI02_RS06765	COG1444	tRNA N-acetyltransferase activity
IAI02_RS06770	COG0400	carboxylic ester hydrolase activity
IAI02_RS06785	COG1393	Belongs to the ArsC family
IAI02_RS06795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAI02_RS06800	COG3850	Histidine kinase
IAI02_RS06805	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS06805	COG0493	'glutamate synthase
IAI02_RS06815	COG5342	invasion associated locus B
IAI02_RS06820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAI02_RS06825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAI02_RS06830	COG0281	malic enzyme
IAI02_RS06830	COG0280	phosphate acetyltransferase
IAI02_RS06835	COG4810	utilization protein
IAI02_RS06840	COG4917	ethanolamine utilization protein
IAI02_RS06845	COG4766	ethanolamine catabolic process
IAI02_RS06850	COG4812	Cobalamin adenosyltransferase
IAI02_RS06860	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IAI02_RS06865	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IAI02_RS06870	COG1012	belongs to the aldehyde dehydrogenase family
IAI02_RS06875	COG4820	ethanolamine utilization protein (EutJ)
IAI02_RS06880	COG1454	alcohol dehydrogenase
IAI02_RS06885	COG3192	ethanolamine utilization protein
IAI02_RS06890	COG4819	ethanolamine utilization protein
IAI02_RS06895	COG4303	Ethanolamine ammonia lyase large subunit
IAI02_RS06905	COG4816	utilization protein
IAI02_RS06910	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IAI02_RS06915	COG2207	Transcriptional regulator
IAI02_RS06925	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAI02_RS06930	COG0456	acetyltransferase
IAI02_RS06945	COG2837	iron assimilation
IAI02_RS06950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAI02_RS06955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS06955	COG1263	PTS System
IAI02_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS06975	COG4150	thiosulfate binding
IAI02_RS06980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IAI02_RS06985	COG4208	sulfate ABC transporter
IAI02_RS06990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IAI02_RS06995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAI02_RS07000	COG4884	unkown
IAI02_RS07000	COG3831	ATPase activity
IAI02_RS07015	COG2190	(PTS) system
IAI02_RS07020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAI02_RS07025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS07030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAI02_RS07050	COG3530	Putative quorum-sensing-regulated virulence factor
IAI02_RS07055	COG0385	Bile acid
IAI02_RS07060	COG0583	DNA-binding transcription factor activity
IAI02_RS07080	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IAI02_RS07085	COG2211	Major facilitator Superfamily
IAI02_RS07095	COG0583	DNA-binding transcription factor activity
IAI02_RS07125	COG3415	Transposase
IAI02_RS07130	COG3415	Transposase
IAI02_RS07145	COG2200	EAL domain
IAI02_RS07145	COG2199	diguanylate cyclase activity
IAI02_RS07150	COG3385	transposase activity
IAI02_RS07155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAI02_RS07185	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS07190	COG4372	Transposase
IAI02_RS07195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS07200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS07205	COG0006	proline dipeptidase activity
IAI02_RS07210	COG1363	Peptidase, m42
IAI02_RS07215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS07215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS07215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAI02_RS07220	COG2207	Transcriptional regulator
IAI02_RS07225	COG3279	Response regulator of the LytR AlgR family
IAI02_RS07230	COG3275	phosphorelay sensor kinase activity
IAI02_RS07235	COG0436	Aminotransferase
IAI02_RS07245	COG1560	Kdo2-lipid A biosynthetic process
IAI02_RS07270	COG0028	Belongs to the TPP enzyme family
IAI02_RS07275	COG0679	Auxin Efflux Carrier
IAI02_RS07280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAI02_RS07285	COG0784	Response regulator, receiver
IAI02_RS07285	COG2205	protein histidine kinase activity
IAI02_RS07285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS07285	COG2198	Histidine kinase
IAI02_RS07290	COG2197	response regulator
IAI02_RS07295	COG1566	PFAM secretion protein HlyD family protein
IAI02_RS07300	COG0477	Major facilitator Superfamily
IAI02_RS07310	COG2610	gluconate transmembrane transporter activity
IAI02_RS07315	COG0583	DNA-binding transcription factor activity
IAI02_RS07325	COG2116	formate transmembrane transporter activity
IAI02_RS07330	COG2853	Lipoprotein
IAI02_RS07340	COG2067	long-chain fatty acid transport protein
IAI02_RS07345	COG3691	Protein conserved in bacteria
IAI02_RS07360	COG2062	phosphohistidine phosphatase, SixA
IAI02_RS07365	COG3539	Fimbrial protein
IAI02_RS07370	COG3188	usher protein
IAI02_RS07375	COG3121	Chaperone
IAI02_RS07380	COG3539	Fimbrial protein
IAI02_RS07385	COG3539	Fimbrial protein
IAI02_RS07390	COG3539	Fimbrial protein
IAI02_RS07405	COG2890	protein-(glutamine-N5) methyltransferase activity
IAI02_RS07420	COG0730	response to heat
IAI02_RS07425	COG3101	peptidyl-lysine hydroxylation
IAI02_RS07440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAI02_RS07445	COG2814	Major facilitator Superfamily
IAI02_RS07460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAI02_RS07470	COG0586	Pfam SNARE associated Golgi protein
IAI02_RS07480	COG0285	dihydrofolate synthase activity
IAI02_RS07485	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IAI02_RS07490	COG1286	toxin biosynthetic process
IAI02_RS07495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAI02_RS07500	COG0163	prenyltransferase activity
IAI02_RS07505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS07510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS07515	COG4215	(ABC) transporter
IAI02_RS07520	COG4160	amino acid transport
IAI02_RS07525	COG4598	ABC transporter
IAI02_RS07530	COG5464	transposase or invertase
IAI02_RS07535	COG1090	epimerase
IAI02_RS07540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAI02_RS07545	COG0625	glutathione transferase activity
IAI02_RS07550	COG0625	glutathione transferase activity
IAI02_RS07555	COG0622	Phosphoesterase
IAI02_RS07560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IAI02_RS07565	COG1288	antiporter activity
IAI02_RS07570	COG0857	belongs to the CobB CobQ family
IAI02_RS07570	COG0280	phosphate acetyltransferase
IAI02_RS07575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAI02_RS07590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAI02_RS07595	COG0471	metal ion transport
IAI02_RS07595	COG0490	domain, Protein
IAI02_RS07605	COG0436	Aminotransferase
IAI02_RS07610	COG0583	DNA-binding transcription factor activity
IAI02_RS07630	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IAI02_RS07635	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IAI02_RS07640	COG1034	ATP synthesis coupled electron transport
IAI02_RS07655	COG0839	Belongs to the complex I subunit 6 family
IAI02_RS07665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAI02_RS07670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAI02_RS07680	COG0457	Tetratricopeptide repeat
IAI02_RS07700	COG2234	aminopeptidase activity
IAI02_RS07705	COG2304	oxidoreductase activity
IAI02_RS07720	COG2153	protein acetylation
IAI02_RS07725	COG4575	ribosome binding
IAI02_RS07730	COG1169	isochorismate synthase
IAI02_RS07745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAI02_RS07755	COG0318	PFAM AMP-dependent synthetase and ligase
IAI02_RS07840	COG2271	Major facilitator Superfamily
IAI02_RS07860	COG0247	lactate metabolic process
IAI02_RS07870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAI02_RS07875	COG2271	Major facilitator Superfamily
IAI02_RS07880	COG0584	glycerophosphoryl diester phosphodiesterase
IAI02_RS07885	COG0583	DNA-binding transcription factor activity
IAI02_RS07890	COG2814	Major facilitator Superfamily
IAI02_RS07895	COG3642	lipopolysaccharide core region biosynthetic process
IAI02_RS07900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAI02_RS07905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAI02_RS07910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAI02_RS07915	COG3468	outer membrane autotransporter barrel domain protein
IAI02_RS07925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAI02_RS07930	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
IAI02_RS07935	COG3234	Protein of unknown function (DUF1175)
IAI02_RS07940	COG2373	Large extracellular alpha-helical protein
IAI02_RS07945	COG5445	Predicted secreted protein (DUF2300)
IAI02_RS07950	COG4676	Protein conserved in bacteria
IAI02_RS07955	COG0784	Response regulator, receiver
IAI02_RS07955	COG2205	protein histidine kinase activity
IAI02_RS07960	COG2197	response regulator
IAI02_RS07965	COG2198	Histidine kinase
IAI02_RS07965	COG0642	Histidine kinase
IAI02_RS07975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAI02_RS07980	COG1477	protein flavinylation
IAI02_RS07985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAI02_RS07985	COG2169	Transcriptional regulator
IAI02_RS07990	COG3145	DNA-N1-methyladenine dioxygenase activity
IAI02_RS07995	COG4615	Cyclic peptide transporter
IAI02_RS08015	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS08015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAI02_RS08020	COG3062	negative regulation of establishment of protein localization
IAI02_RS08030	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS08035	COG0348	domain, Protein
IAI02_RS08040	COG3043	anaerobic respiration
IAI02_RS08045	COG3005	denitrification pathway
IAI02_RS08050	COG4133	protoheme IX ABC transporter activity
IAI02_RS08055	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAI02_RS08060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAI02_RS08065	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAI02_RS08075	COG1138	Cytochrome C-type biogenesis protein
IAI02_RS08080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAI02_RS08085	COG3088	subunit of a heme lyase
IAI02_RS08085	COG4235	cytochrome complex assembly
IAI02_RS08090	COG2197	response regulator
IAI02_RS08095	COG3468	outer membrane autotransporter barrel domain protein
IAI02_RS08105	COG3083	sulfuric ester hydrolase activity
IAI02_RS08125	COG1061	Type III restriction enzyme res subunit
IAI02_RS08130	COG1187	pseudouridine synthase activity
IAI02_RS08135	COG2814	Major facilitator Superfamily
IAI02_RS08145	COG4172	Belongs to the ABC transporter superfamily
IAI02_RS08150	COG4239	(ABC) transporter, permease
IAI02_RS08155	COG4174	ABC transporter (Permease)
IAI02_RS08160	COG4166	transmembrane transport
IAI02_RS08165	COG2200	EAL domain
IAI02_RS08170	COG0791	NLP P60 protein
IAI02_RS08175	COG3039	Transposase
IAI02_RS08180	COG0671	phosphoesterase, PA-phosphatase related
IAI02_RS08185	COG0523	cobalamin synthesis protein
IAI02_RS08190	COG0246	Mannitol dehydrogenase
IAI02_RS08205	COG2814	Major facilitator Superfamily
IAI02_RS08210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS08210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS08215	COG1105	Belongs to the carbohydrate kinase PfkB family
IAI02_RS08220	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IAI02_RS08220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS08220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS08225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS08230	COG2313	pseudouridylate synthase activity
IAI02_RS08235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAI02_RS08240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAI02_RS08250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAI02_RS08255	COG1522	sequence-specific DNA binding
IAI02_RS08255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS08265	COG2855	membrane
IAI02_RS08270	COG0583	DNA-binding transcription factor activity
IAI02_RS08275	COG0833	amino acid
IAI02_RS08280	COG4771	TonB-dependent receptor
IAI02_RS08295	COG2311	Membrane
IAI02_RS08300	COG1609	Transcriptional regulator
IAI02_RS08305	COG1879	ABC-type sugar transport system periplasmic component
IAI02_RS08310	COG1129	ABC transporter
IAI02_RS08315	COG4211	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS08320	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IAI02_RS08320	COG0167	dihydroorotate dehydrogenase activity
IAI02_RS08325	COG0493	'glutamate synthase
IAI02_RS08335	COG2949	membrane
IAI02_RS08345	COG1346	cytolysis
IAI02_RS08355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAI02_RS08375	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS08380	COG0586	Pfam SNARE associated Golgi protein
IAI02_RS08390	COG1686	Belongs to the peptidase S11 family
IAI02_RS08395	COG0277	FAD linked oxidase domain protein
IAI02_RS08400	COG1472	Belongs to the glycosyl hydrolase 3 family
IAI02_RS08405	COG1732	Glycine betaine
IAI02_RS08410	COG1174	glycine betaine transport
IAI02_RS08415	COG1125	glycine betaine transport
IAI02_RS08420	COG1174	glycine betaine transport
IAI02_RS08430	COG0789	Transcriptional regulator
IAI02_RS08435	COG3275	phosphorelay sensor kinase activity
IAI02_RS08440	COG3279	Response regulator of the LytR AlgR family
IAI02_RS08445	COG4807	Protein conserved in bacteria
IAI02_RS08450	COG4808	Protein conserved in bacteria
IAI02_RS08455	COG4715	Zinc finger, swim domain protein
IAI02_RS08460	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IAI02_RS08465	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IAI02_RS08470	COG0714	Associated with various cellular activities
IAI02_RS08480	COG3831	ATPase activity
IAI02_RS08485	COG3831	ATPase activity
IAI02_RS08495	COG0489	protein tyrosine kinase activity
IAI02_RS08505	COG3539	Fimbrial protein
IAI02_RS08510	COG3121	Chaperone
IAI02_RS08515	COG3188	usher protein
IAI02_RS08520	COG3539	Fimbrial protein
IAI02_RS08525	COG5455	response to cobalt ion
IAI02_RS08530	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IAI02_RS08590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IAI02_RS08630	COG0351	phosphomethylpyrimidine kinase
IAI02_RS08640	COG2188	Transcriptional regulator
IAI02_RS08645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS08650	COG1397	ADP-ribosylglycohydrolase
IAI02_RS08655	COG2211	Major facilitator Superfamily
IAI02_RS08660	COG1830	Aldolase
IAI02_RS08675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS08680	COG3414	Phosphotransferase system galactitol-specific IIB component
IAI02_RS08685	COG3775	system Galactitol-specific IIC component
IAI02_RS08690	COG1063	alcohol dehydrogenase
IAI02_RS08710	COG0826	peptidase U32
IAI02_RS08720	COG0745	RESPONSE REGULATOR receiver
IAI02_RS08725	COG2205	protein histidine kinase activity
IAI02_RS08760	COG4245	von Willebrand factor, type A
IAI02_RS08765	COG0631	protein serine/threonine phosphatase activity
IAI02_RS08770	COG3779	Protein conserved in bacteria
IAI02_RS08775	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
IAI02_RS08780	COG0443	Heat shock 70 kDa protein
IAI02_RS08785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IAI02_RS08790	COG3447	MASE1 domain protein
IAI02_RS08790	COG5001	Diguanylate cyclase
IAI02_RS08790	COG5002	protein histidine kinase activity
IAI02_RS08795	COG0572	uridine kinase
IAI02_RS08805	COG2982	Protein involved in outer membrane biogenesis
IAI02_RS08810	COG1253	flavin adenine dinucleotide binding
IAI02_RS08820	COG1596	polysaccharide export
IAI02_RS08825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAI02_RS08830	COG0489	protein tyrosine kinase activity
IAI02_RS08830	COG3206	protein involved in exopolysaccharide biosynthesis
IAI02_RS08835	COG0463	Glycosyl transferase, family 2
IAI02_RS08840	COG1045	serine acetyltransferase
IAI02_RS08845	COG0438	transferase activity, transferring glycosyl groups
IAI02_RS08855	COG1216	Glycosyl transferase, family 2
IAI02_RS08860	COG0110	maltose O-acetyltransferase activity
IAI02_RS08865	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IAI02_RS08870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAI02_RS08875	COG1051	belongs to the nudix hydrolase family
IAI02_RS08880	COG0297	glycogen (starch) synthase activity
IAI02_RS08885	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IAI02_RS08885	COG0662	Cupin 2, conserved barrel domain protein
IAI02_RS08890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAI02_RS08895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAI02_RS08900	COG2244	polysaccharide biosynthetic process
IAI02_RS08905	COG2327	Polysaccharide pyruvyl transferase
IAI02_RS08910	COG0438	transferase activity, transferring glycosyl groups
IAI02_RS08920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAI02_RS08935	COG1086	Polysaccharide biosynthesis protein
IAI02_RS08965	COG2244	polysaccharide biosynthetic process
IAI02_RS08975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAI02_RS08980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAI02_RS08985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IAI02_RS08995	COG0426	domain, Protein
IAI02_RS08995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAI02_RS09000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IAI02_RS09020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAI02_RS09025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IAI02_RS09025	COG0131	Imidazoleglycerol-phosphate dehydratase
IAI02_RS09035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAI02_RS09050	COG2161	toxin-antitoxin pair type II binding
IAI02_RS09055	COG4115	mRNA cleavage
IAI02_RS09060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAI02_RS09065	COG0583	DNA-binding transcription factor activity
IAI02_RS09075	COG0531	amino acid
IAI02_RS09080	COG2391	methyltransferase activity
IAI02_RS09085	COG0425	Belongs to the sulfur carrier protein TusA family
IAI02_RS09090	COG2925	Exonuclease
IAI02_RS09095	COG1686	Belongs to the peptidase S11 family
IAI02_RS09105	COG1289	transmembrane transporter activity
IAI02_RS09125	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
IAI02_RS09140	COG1376	ErfK ybiS ycfS ynhG family protein
IAI02_RS09150	COG0583	DNA-binding transcription factor activity
IAI02_RS09155	COG0583	DNA-binding transcription factor activity
IAI02_RS09165	COG0534	Mate efflux family protein
IAI02_RS09175	COG0217	transcriptional regulatory protein
IAI02_RS09180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAI02_RS09185	COG0477	Major facilitator Superfamily
IAI02_RS09195	COG4372	Transposase
IAI02_RS09200	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS09215	COG1470	cell adhesion involved in biofilm formation
IAI02_RS09215	COG1388	LysM domain
IAI02_RS09235	COG3038	cytochrome b561
IAI02_RS09240	COG3443	Belongs to the bacterial solute-binding protein 9 family
IAI02_RS09255	COG2351	hydroxyisourate hydrolase activity
IAI02_RS09260	COG0745	RESPONSE REGULATOR receiver
IAI02_RS09265	COG2205	protein histidine kinase activity
IAI02_RS09285	COG0270	DNA (cytosine-5-)-methyltransferase activity
IAI02_RS09290	COG3727	T/G mismatch-specific endonuclease activity
IAI02_RS09295	COG0697	spore germination
IAI02_RS09300	COG2354	Protein conserved in bacteria
IAI02_RS09305	COG5475	Uncharacterized small protein (DUF2158)
IAI02_RS09340	COG2197	response regulator
IAI02_RS09345	COG1684	flagellar biosynthetic protein fliR
IAI02_RS09350	COG1987	bacterial-type flagellum assembly
IAI02_RS09355	COG1338	Plays a role in the flagellum-specific transport system
IAI02_RS09360	COG3190	flagellar
IAI02_RS09365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAI02_RS09370	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAI02_RS09375	COG1580	Controls the rotational direction of flagella during chemotaxis
IAI02_RS09380	COG3144	bacterial-type flagellum assembly
IAI02_RS09385	COG2882	bacterial-type flagellum organization
IAI02_RS09390	COG1157	protein secretion by the type III secretion system
IAI02_RS09395	COG1317	bacterial-type flagellum organization
IAI02_RS09400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAI02_RS09405	COG1766	The M ring may be actively involved in energy transduction
IAI02_RS09415	COG2135	peptidase activity
IAI02_RS09420	COG0425	Belongs to the sulfur carrier protein TusA family
IAI02_RS09425	COG2391	methyltransferase activity
IAI02_RS09435	COG0366	Alpha amylase catalytic
IAI02_RS09445	COG1516	flagellar protein fliS
IAI02_RS09460	COG1191	sigma factor activity
IAI02_RS09470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS09480	COG0765	amino acid transport
IAI02_RS09485	COG1126	abc transporter atp-binding protein
IAI02_RS09490	COG2197	response regulator
IAI02_RS09505	COG2197	response regulator
IAI02_RS09535	COG3012	SEC-C Motif Domain Protein
IAI02_RS09535	COG3318	Belongs to the UPF0149 family
IAI02_RS09540	COG0814	amino acid
IAI02_RS09550	COG1528	Iron-storage protein
IAI02_RS09570	COG1528	Iron-storage protein
IAI02_RS09575	COG1879	ABC-type sugar transport system periplasmic component
IAI02_RS09580	COG1129	ABC transporter
IAI02_RS09585	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS09590	COG1877	trehalose-phosphatase activity
IAI02_RS09600	COG0589	response to stress
IAI02_RS09615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IAI02_RS09620	COG1360	Flagellar Motor Protein
IAI02_RS09625	COG2198	Histidine kinase
IAI02_RS09625	COG0643	Histidine kinase
IAI02_RS09630	COG0835	chemotaxis
IAI02_RS09635	COG0840	transmembrane signaling receptor activity
IAI02_RS09640	COG0840	transmembrane signaling receptor activity
IAI02_RS09645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IAI02_RS09655	COG0745	RESPONSE REGULATOR receiver
IAI02_RS09660	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IAI02_RS09665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAI02_RS09670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAI02_RS09685	COG3755	Protein conserved in bacteria
IAI02_RS09695	COG3102	Protein conserved in bacteria
IAI02_RS09705	COG3005	denitrification pathway
IAI02_RS09710	COG0243	molybdopterin cofactor binding
IAI02_RS09725	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IAI02_RS09730	COG1801	Protein of unknown function DUF72
IAI02_RS09735	COG1335	isochorismatase
IAI02_RS09745	COG0494	nUDIX hydrolase
IAI02_RS09750	COG0217	transcriptional regulatory protein
IAI02_RS09780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAI02_RS09790	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IAI02_RS09795	COG0739	heme binding
IAI02_RS09800	COG1560	Kdo2-lipid A biosynthetic process
IAI02_RS09810	COG1737	Transcriptional regulator
IAI02_RS09815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAI02_RS09820	COG0129	dihydroxy-acid dehydratase activity
IAI02_RS09825	COG0800	Aldolase
IAI02_RS09835	COG3141	response to X-ray
IAI02_RS09845	COG2979	Protein of unknown function (DUF533)
IAI02_RS09850	COG1770	oligopeptidase
IAI02_RS09855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAI02_RS09860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAI02_RS09870	COG2372	response to copper ion
IAI02_RS09875	COG1276	copper resistance
IAI02_RS09885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAI02_RS09905	COG3008	intermembrane lipid transfer
IAI02_RS09910	COG2995	paraquat-inducible protein a
IAI02_RS09915	COG1956	GAF domain-containing protein
IAI02_RS09925	COG0793	Belongs to the peptidase S41A family
IAI02_RS09935	COG2814	Major facilitator Superfamily
IAI02_RS09940	COG1414	Transcriptional regulator
IAI02_RS09970	COG2226	methyltransferase
IAI02_RS09985	COG3716	PTS system mannose fructose sorbose family IID component
IAI02_RS09990	COG3715	PTS system
IAI02_RS09995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS09995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS10000	COG1253	flavin adenine dinucleotide binding
IAI02_RS10005	COG2200	EAL domain
IAI02_RS10010	COG1760	l-serine dehydratase
IAI02_RS10020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAI02_RS10035	COG0251	oxidation-reduction process
IAI02_RS10040	COG1199	ATP-dependent helicase activity
IAI02_RS10045	COG1214	PFAM Peptidase M22, glycoprotease
IAI02_RS10050	COG3065	identical protein binding
IAI02_RS10055	COG0318	PFAM AMP-dependent synthetase and ligase
IAI02_RS10060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IAI02_RS10065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAI02_RS10070	COG4638	Rieske (2fe-2S)
IAI02_RS10085	COG0583	DNA-binding transcription factor activity
IAI02_RS10100	COG3615	Tellurite resistance protein tehB
IAI02_RS10105	COG3385	transposase activity
IAI02_RS10120	COG2261	transglycosylase associated protein
IAI02_RS10135	COG2199	diguanylate cyclase activity
IAI02_RS10135	COG2203	Gaf domain
IAI02_RS10140	COG3042	response to heat
IAI02_RS10145	COG3189	MarR family transcriptional regulator
IAI02_RS10150	COG2807	transmembrane transport
IAI02_RS10155	COG2207	Transcriptional regulator
IAI02_RS10170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAI02_RS10175	COG2199	diguanylate cyclase activity
IAI02_RS10180	COG2199	diguanylate cyclase activity
IAI02_RS10190	COG2766	serine protein kinase
IAI02_RS10195	COG3713	MltA-interacting MipA family protein
IAI02_RS10200	COG0656	L-ascorbic acid biosynthetic process
IAI02_RS10205	COG0676	glucose-6-phosphate 1-epimerase activity
IAI02_RS10210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAI02_RS10220	COG3139	Protein of unknown function (DUF1315)
IAI02_RS10225	COG1063	alcohol dehydrogenase
IAI02_RS10230	COG2271	Major facilitator Superfamily
IAI02_RS10235	COG1063	alcohol dehydrogenase
IAI02_RS10240	COG0191	fructose-bisphosphate aldolase activity
IAI02_RS10245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS10250	COG0667	Aldo Keto reductase
IAI02_RS10255	COG1349	DNA-binding transcription factor activity
IAI02_RS10260	COG2814	Major facilitator Superfamily
IAI02_RS10265	COG1335	isochorismatase
IAI02_RS10270	COG0252	asparaginase activity
IAI02_RS10275	COG0616	signal peptide processing
IAI02_RS10280	COG0778	Nitroreductase
IAI02_RS10290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAI02_RS10300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAI02_RS10310	COG0494	nUDIX hydrolase
IAI02_RS10315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAI02_RS10320	COG2897	thiosulfate sulfurtransferase activity
IAI02_RS10325	COG4136	ATPase activity
IAI02_RS10330	COG4135	transport system, permease component
IAI02_RS10335	COG4134	Bacterial extracellular solute-binding protein
IAI02_RS10340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAI02_RS10345	COG0398	Pfam SNARE associated Golgi protein
IAI02_RS10355	COG0398	Pfam SNARE associated Golgi protein
IAI02_RS10360	COG0708	Exodeoxyribonuclease III
IAI02_RS10390	COG3678	ATP-independent chaperone mediated protein folding
IAI02_RS10400	COG0322	excinuclease ABC activity
IAI02_RS10410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAI02_RS10415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAI02_RS10420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAI02_RS10425	COG1447	Phosphotransferase system cellobiose-specific component IIA
IAI02_RS10430	COG2169	Transcriptional regulator
IAI02_RS10430	COG1917	Cupin 2, conserved barrel domain protein
IAI02_RS10435	COG1486	melibiose metabolic process
IAI02_RS10445	COG0753	catalase activity
IAI02_RS10470	COG1823	symporter activity
IAI02_RS10475	COG1988	membrane-bound metal-dependent
IAI02_RS10480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAI02_RS10490	COG3001	Fructosamine kinase
IAI02_RS10500	COG1105	Belongs to the carbohydrate kinase PfkB family
IAI02_RS10505	COG3137	Salt-induced outer membrane protein
IAI02_RS10550	COG0072	phenylalanine-tRNA ligase activity
IAI02_RS10550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAI02_RS10565	COG0386	Belongs to the glutathione peroxidase family
IAI02_RS10575	COG0791	NLP P60 protein
IAI02_RS10580	COG2200	EAL domain
IAI02_RS10590	COG4256	Hemin uptake protein
IAI02_RS10595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAI02_RS10605	COG0574	Belongs to the PEP-utilizing enzyme family
IAI02_RS10605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAI02_RS10610	COG0318	PFAM AMP-dependent synthetase and ligase
IAI02_RS10615	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAI02_RS10620	COG0644	oxidoreductase
IAI02_RS10625	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IAI02_RS10630	COG2086	electron transfer activity
IAI02_RS10635	COG1917	Cupin 2, conserved barrel domain protein
IAI02_RS10635	COG2207	Transcriptional regulator
IAI02_RS10640	COG1960	acyl-CoA dehydrogenase activity
IAI02_RS10645	COG4670	ketone body catabolic process
IAI02_RS10660	COG2271	Major facilitator Superfamily
IAI02_RS10665	COG0738	Major facilitator superfamily
IAI02_RS10680	COG0628	permease
IAI02_RS10685	COG0247	lactate metabolic process
IAI02_RS10685	COG0277	FAD linked oxidase domain protein
IAI02_RS10690	COG2050	protein possibly involved in aromatic compounds catabolism
IAI02_RS10700	COG0316	Belongs to the HesB IscA family
IAI02_RS10705	COG0719	Fe-S assembly protein
IAI02_RS10710	COG0396	ATPase activity
IAI02_RS10715	COG0719	Fe-S assembly protein
IAI02_RS10730	COG1376	ErfK ybiS ycfS ynhG family protein
IAI02_RS10735	COG4238	major outer membrane lipoprotein
IAI02_RS10740	COG0469	pyruvate kinase activity
IAI02_RS10750	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS10755	COG2414	aldehyde ferredoxin oxidoreductase
IAI02_RS10765	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS10770	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IAI02_RS10780	COG4529	Protein conserved in bacteria
IAI02_RS10800	COG3468	outer membrane autotransporter barrel domain protein
IAI02_RS10810	COG0307	riboflavin synthase, alpha
IAI02_RS10815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IAI02_RS10820	COG2814	Major facilitator Superfamily
IAI02_RS10825	COG0583	DNA-binding transcription factor activity
IAI02_RS10840	COG2814	Major facilitator Superfamily
IAI02_RS10845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAI02_RS10850	COG0791	NLP P60 protein
IAI02_RS10855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IAI02_RS10865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAI02_RS10870	COG0346	lactoylglutathione lyase activity
IAI02_RS10875	COG1902	pentaerythritol trinitrate reductase activity
IAI02_RS10880	COG1309	transcriptional regulator
IAI02_RS10885	COG3313	Fe-S protein
IAI02_RS10890	COG4989	oxidoreductase activity
IAI02_RS10895	COG2032	superoxide dismutase activity
IAI02_RS10900	COG1289	transmembrane transporter activity
IAI02_RS10905	COG1566	PFAM secretion protein HlyD family protein
IAI02_RS10920	COG3133	Outer membrane lipoprotein
IAI02_RS10930	COG3895	Periplasmic Protein
IAI02_RS10945	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IAI02_RS10950	COG0625	glutathione transferase activity
IAI02_RS10955	COG3104	oligopeptide transport
IAI02_RS10960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAI02_RS10970	COG4659	FMN binding
IAI02_RS11010	COG0673	inositol 2-dehydrogenase activity
IAI02_RS11020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IAI02_RS11035	COG1482	cell wall glycoprotein biosynthetic process
IAI02_RS11040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IAI02_RS11040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAI02_RS11045	COG0114	fumarate hydratase activity
IAI02_RS11055	COG2205	protein histidine kinase activity
IAI02_RS11060	COG0745	RESPONSE REGULATOR receiver
IAI02_RS11065	COG3136	membrane protein required for alginate biosynthesis
IAI02_RS11075	COG0531	amino acid
IAI02_RS11085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IAI02_RS11090	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IAI02_RS11095	COG0628	permease
IAI02_RS11110	COG3591	Belongs to the peptidase S1B family
IAI02_RS11125	COG2814	Major facilitator Superfamily
IAI02_RS11130	COG0583	DNA-binding transcription factor activity
IAI02_RS11135	COG1940	carbohydrate kinase activity
IAI02_RS11140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IAI02_RS11150	COG3381	protein complex oligomerization
IAI02_RS11155	COG3302	dmso reductase anchor subunit
IAI02_RS11160	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS11165	COG0243	molybdopterin cofactor binding
IAI02_RS11170	COG0243	molybdopterin cofactor binding
IAI02_RS11185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAI02_RS11200	COG4948	Mandelate Racemase Muconate Lactonizing
IAI02_RS11205	COG1063	alcohol dehydrogenase
IAI02_RS11210	COG0477	Major facilitator Superfamily
IAI02_RS11215	COG0246	Mannitol dehydrogenase
IAI02_RS11225	COG1802	Transcriptional regulator
IAI02_RS11230	COG4221	oxidoreductase activity
IAI02_RS11235	COG0339	signal peptide processing
IAI02_RS11240	COG1546	Belongs to the CinA family
IAI02_RS11245	COG3111	PFAM Bacterial OB fold (BOF) protein
IAI02_RS11250	COG3706	GGDEF domain
IAI02_RS11260	COG2814	Major facilitator Superfamily
IAI02_RS11265	COG0697	spore germination
IAI02_RS11275	COG4977	sequence-specific DNA binding
IAI02_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
IAI02_RS11320	COG2066	Belongs to the glutaminase family
IAI02_RS11340	COG3781	membrane
IAI02_RS11390	COG3210	domain, Protein
IAI02_RS11390	COG2911	Protein conserved in bacteria
IAI02_RS11395	COG1396	sequence-specific DNA binding
IAI02_RS11400	COG3550	peptidyl-serine autophosphorylation
IAI02_RS11430	COG3706	GGDEF domain
IAI02_RS11435	COG2200	EAL domain
IAI02_RS11435	COG2202	Pas domain
IAI02_RS11435	COG2199	diguanylate cyclase activity
IAI02_RS11440	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IAI02_RS11445	COG0747	negative chemotaxis
IAI02_RS11450	COG0601	transmembrane transport
IAI02_RS11455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAI02_RS11460	COG0444	Belongs to the ABC transporter superfamily
IAI02_RS11465	COG4608	Belongs to the ABC transporter superfamily
IAI02_RS11470	COG1764	response to oxidative stress
IAI02_RS11490	COG1064	alcohol dehydrogenase
IAI02_RS11495	COG3093	addiction module antidote protein HigA
IAI02_RS11500	COG2864	formate dehydrogenase
IAI02_RS11505	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS11515	COG0697	spore germination
IAI02_RS11520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAI02_RS11540	COG2223	nitrite transmembrane transporter activity
IAI02_RS11545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAI02_RS11550	COG1140	nitrate reductase beta subunit
IAI02_RS11555	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IAI02_RS11560	COG2181	nitrate reductase activity
IAI02_RS11565	COG0384	phenazine biosynthesis protein PhzF
IAI02_RS11570	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IAI02_RS11575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAI02_RS11585	COG5433	transposase activity
IAI02_RS11605	COG3209	COG3209 Rhs family protein
IAI02_RS11630	COG1113	amino acid transport
IAI02_RS11635	COG3391	amine dehydrogenase activity
IAI02_RS11640	COG4772	TonB-dependent receptor
IAI02_RS11645	COG1802	Transcriptional regulator
IAI02_RS11650	COG2130	NADP-dependent
IAI02_RS11655	COG1247	-acetyltransferase
IAI02_RS11660	COG3238	Protein conserved in bacteria
IAI02_RS11685	COG1177	transmembrane transport
IAI02_RS11690	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAI02_RS11695	COG3842	ATPase activity
IAI02_RS11700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IAI02_RS11705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAI02_RS11710	COG1598	PFAM Uncharacterised protein family UPF0150
IAI02_RS11715	COG1724	mRNA binding
IAI02_RS11725	COG0826	peptidase U32
IAI02_RS11730	COG1396	sequence-specific DNA binding
IAI02_RS11735	COG3135	benzoate transporter
IAI02_RS11740	COG0675	Transposase, IS605 OrfB family
IAI02_RS11755	COG0500	methyltransferase
IAI02_RS11760	COG1275	C4-dicarboxylate transporter malic acid transport protein
IAI02_RS11765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAI02_RS11770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAI02_RS11775	COG2841	Protein conserved in bacteria
IAI02_RS11785	COG5383	Protein conserved in bacteria
IAI02_RS11790	COG0583	DNA-binding transcription factor activity
IAI02_RS11795	COG0840	transmembrane signaling receptor activity
IAI02_RS11810	COG3038	cytochrome b561
IAI02_RS11815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAI02_RS11820	COG1012	belongs to the aldehyde dehydrogenase family
IAI02_RS11825	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IAI02_RS11830	COG1643	Atp-dependent helicase
IAI02_RS11840	COG2453	phosphatase
IAI02_RS11840	COG0671	phosphoesterase, PA-phosphatase related
IAI02_RS11845	COG2267	carboxylic ester hydrolase activity
IAI02_RS11865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAI02_RS11870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAI02_RS11875	COG0589	response to stress
IAI02_RS11880	COG3182	Iron-regulated membrane protein
IAI02_RS11885	COG0668	transmembrane transport
IAI02_RS11890	COG4166	transmembrane transport
IAI02_RS11895	COG0583	DNA-binding transcription factor activity
IAI02_RS11900	COG1073	alpha beta
IAI02_RS11915	COG2866	Carboxypeptidase
IAI02_RS11920	COG4948	Mandelate Racemase Muconate Lactonizing
IAI02_RS11925	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IAI02_RS11930	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IAI02_RS11940	COG3106	COG3106 Predicted ATPase
IAI02_RS11945	COG1609	Transcriptional regulator
IAI02_RS11980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAI02_RS11985	COG1554	hydrolase, family 65, central catalytic
IAI02_RS11990	COG0673	inositol 2-dehydrogenase activity
IAI02_RS11995	COG1082	Xylose isomerase domain protein TIM barrel
IAI02_RS12000	COG1063	alcohol dehydrogenase
IAI02_RS12005	COG0395	ABC-type sugar transport system, permease component
IAI02_RS12010	COG1175	transmembrane transport
IAI02_RS12015	COG1653	transport
IAI02_RS12020	COG0366	Alpha amylase catalytic
IAI02_RS12025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAI02_RS12035	COG1983	PspC domain protein
IAI02_RS12045	COG1842	Phage shock protein A
IAI02_RS12050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IAI02_RS12055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAI02_RS12060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAI02_RS12065	COG1012	belongs to the aldehyde dehydrogenase family
IAI02_RS12070	COG1396	sequence-specific DNA binding
IAI02_RS12070	COG1917	Cupin 2, conserved barrel domain protein
IAI02_RS12075	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IAI02_RS12080	COG0174	glutamine synthetase
IAI02_RS12090	COG0531	amino acid
IAI02_RS12100	COG4166	transmembrane transport
IAI02_RS12105	COG4168	peptide transport system, permease
IAI02_RS12110	COG4171	peptide transport system, permease
IAI02_RS12115	COG4172	Belongs to the ABC transporter superfamily
IAI02_RS12120	COG4172	Belongs to the ABC transporter superfamily
IAI02_RS12125	COG2852	Protein conserved in bacteria
IAI02_RS12130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IAI02_RS12135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAI02_RS12135	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAI02_RS12150	COG5001	Diguanylate cyclase
IAI02_RS12160	COG1349	DNA-binding transcription factor activity
IAI02_RS12170	COG0023	Translation Initiation Factor
IAI02_RS12180	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IAI02_RS12185	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IAI02_RS12190	COG0671	phosphoesterase, PA-phosphatase related
IAI02_RS12200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAI02_RS12220	COG0583	DNA-binding transcription factor activity
IAI02_RS12225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAI02_RS12235	COG0616	signal peptide processing
IAI02_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS12245	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IAI02_RS12250	COG1187	pseudouridine synthase activity
IAI02_RS12255	COG4907	membrane protein (DUF2207)
IAI02_RS12260	COG0009	L-threonylcarbamoyladenylate synthase
IAI02_RS12265	COG0613	PHP domain protein
IAI02_RS12275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAI02_RS12280	COG0512	Glutamine amidotransferase of anthranilate synthase
IAI02_RS12280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAI02_RS12285	COG0135	phosphoribosylanthranilate isomerase activity
IAI02_RS12285	COG0134	indole-3-glycerol-phosphate synthase activity
IAI02_RS12310	COG3047	cAMP biosynthetic process
IAI02_RS12330	COG1607	acyl-coa hydrolase
IAI02_RS12335	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IAI02_RS12340	COG2350	Protein conserved in bacteria
IAI02_RS12345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAI02_RS12365	COG4608	Belongs to the ABC transporter superfamily
IAI02_RS12370	COG0444	Belongs to the ABC transporter superfamily
IAI02_RS12375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAI02_RS12380	COG0601	transmembrane transport
IAI02_RS12385	COG4166	transmembrane transport
IAI02_RS12395	COG2095	MarC family integral membrane protein
IAI02_RS12400	COG1454	alcohol dehydrogenase
IAI02_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
IAI02_RS12405	COG1435	thymidine kinase activity
IAI02_RS12415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAI02_RS12420	COG0745	RESPONSE REGULATOR receiver
IAI02_RS12425	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAI02_RS12435	COG0788	formyltetrahydrofolate deformylase activity
IAI02_RS12470	COG2181	nitrate reductase activity
IAI02_RS12475	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IAI02_RS12480	COG1140	nitrate reductase beta subunit
IAI02_RS12485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAI02_RS12490	COG2223	nitrite transmembrane transporter activity
IAI02_RS12495	COG3850	Histidine kinase
IAI02_RS12500	COG2197	response regulator
IAI02_RS12505	COG4932	domain protein
IAI02_RS12510	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IAI02_RS12515	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IAI02_RS12520	COG4572	Cation transport regulator
IAI02_RS12525	COG0387	Pfam Sodium calcium exchanger
IAI02_RS12550	COG2912	Transglutaminase-like superfamily
IAI02_RS12555	COG3094	Invasion gene expression up-regulator, SirB
IAI02_RS12560	COG2890	protein-(glutamine-N5) methyltransferase activity
IAI02_RS12585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAI02_RS12590	COG0659	secondary active sulfate transmembrane transporter activity
IAI02_RS12605	COG0012	GTP binding
IAI02_RS12615	COG3284	Transcriptional regulator
IAI02_RS12620	COG2376	Dihydroxyacetone kinase
IAI02_RS12625	COG1461	Dihydroxyacetone kinase
IAI02_RS12630	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IAI02_RS12630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS12630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAI02_RS12645	COG2261	transglycosylase associated protein
IAI02_RS12650	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IAI02_RS12660	COG1619	proteins homologs of microcin C7 resistance protein MccF
IAI02_RS12670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAI02_RS12680	COG2719	SpoVR family
IAI02_RS12695	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAI02_RS12700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAI02_RS12705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAI02_RS12720	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAI02_RS12745	COG2894	cell division
IAI02_RS12795	COG2200	EAL domain
IAI02_RS12820	COG2200	EAL domain
IAI02_RS12825	COG0789	Transcriptional regulator
IAI02_RS12830	COG5562	phage envelope protein
IAI02_RS12850	COG0538	isocitrate dehydrogenase activity
IAI02_RS12855	COG4372	Transposase
IAI02_RS12860	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS12880	COG1401	restriction endodeoxyribonuclease activity
IAI02_RS12950	COG1475	DNA binding
IAI02_RS12955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAI02_RS12985	COG1403	HNH endonuclease
IAI02_RS12995	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IAI02_RS13005	COG4725	Belongs to the MT-A70-like family
IAI02_RS13015	COG1846	Transcriptional regulator
IAI02_RS13060	COG5532	Uncharacterized conserved protein (DUF2303)
IAI02_RS13065	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IAI02_RS13075	COG0582	viral genome integration into host DNA
IAI02_RS13090	COG0538	isocitrate dehydrogenase activity
IAI02_RS13095	COG1187	pseudouridine synthase activity
IAI02_RS13115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAI02_RS13120	COG0745	RESPONSE REGULATOR receiver
IAI02_RS13125	COG2205	protein histidine kinase activity
IAI02_RS13130	COG2850	peptidyl-arginine hydroxylation
IAI02_RS13160	COG1177	transmembrane transport
IAI02_RS13165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IAI02_RS13175	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IAI02_RS13180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAI02_RS13190	COG4591	ABC-type transport system involved in lipoprotein release permease component
IAI02_RS13195	COG1136	(ABC) transporter
IAI02_RS13200	COG4591	ABC-type transport system involved in lipoprotein release permease component
IAI02_RS13205	COG4763	Acyl-transferase
IAI02_RS13210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAI02_RS13215	COG1376	ErfK ybiS ycfS ynhG family protein
IAI02_RS13215	COG1388	LysM domain
IAI02_RS13225	COG1309	transcriptional regulator
IAI02_RS13230	COG3134	Outer membrane lipoprotein
IAI02_RS13235	COG1252	NADH dehydrogenase
IAI02_RS13255	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IAI02_RS13260	COG5633	Lipoprotein
IAI02_RS13265	COG0537	adenosine 5'-monophosphoramidase activity
IAI02_RS13270	COG4773	Receptor
IAI02_RS13275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS13275	COG1263	PTS System
IAI02_RS13280	COG0084	hydrolase, TatD family'
IAI02_RS13285	COG0470	DNA polymerase III
IAI02_RS13295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAI02_RS13300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAI02_RS13305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAI02_RS13315	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS13320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAI02_RS13340	COG1399	metal-binding, possibly nucleic acid-binding protein
IAI02_RS13345	COG0424	maF-like protein
IAI02_RS13350	COG0564	pseudouridine synthase activity
IAI02_RS13355	COG1530	ribonuclease E activity
IAI02_RS13360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IAI02_RS13365	COG1256	bacterial-type flagellum assembly
IAI02_RS13370	COG3951	Flagellar rod assembly protein muramidase FlgJ
IAI02_RS13370	COG1705	Flagellar rod assembly protein muramidase FlgJ
IAI02_RS13385	COG4786	Flagellar basal body rod
IAI02_RS13390	COG4787	bacterial-type flagellum-dependent cell motility
IAI02_RS13395	COG1749	Flagellar hook protein flgE
IAI02_RS13400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IAI02_RS13405	COG1558	bacterial-type flagellum-dependent cell motility
IAI02_RS13410	COG1815	bacterial-type flagellum-dependent cell motility
IAI02_RS13415	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IAI02_RS13420	COG2747	anti-sigma28 factor FlgM
IAI02_RS13425	COG3418	PFAM FlgN family protein
IAI02_RS13430	COG0728	peptidoglycan biosynthetic process
IAI02_RS13435	COG0673	inositol 2-dehydrogenase activity
IAI02_RS13445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAI02_RS13455	COG2999	glutathione oxidoreductase activity
IAI02_RS13490	COG3038	cytochrome b561
IAI02_RS13495	COG2353	YceI-like domain
IAI02_RS13505	COG1560	Kdo2-lipid A biosynthetic process
IAI02_RS13520	COG5645	(Lipo)protein
IAI02_RS13525	COG2943	transferase activity, transferring hexosyl groups
IAI02_RS13540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAI02_RS13545	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IAI02_RS13565	COG2197	response regulator
IAI02_RS13580	COG1462	curli production assembly transport component CsgG
IAI02_RS13590	COG3381	protein complex oligomerization
IAI02_RS13625	COG3706	GGDEF domain
IAI02_RS13635	COG0726	polysaccharide deacetylase
IAI02_RS13635	COG1649	PFAM Uncharacterised BCR, COG1649
IAI02_RS13640	COG1215	transferase activity, transferring glycosyl groups
IAI02_RS13645	COG3658	cytochrome
IAI02_RS13650	COG1702	phosphate starvation-inducible protein PhoH
IAI02_RS13655	COG2837	iron assimilation
IAI02_RS13660	COG2822	iron ion transport
IAI02_RS13670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAI02_RS13680	COG0506	proline dehydrogenase activity
IAI02_RS13680	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAI02_RS13680	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAI02_RS13685	COG1309	transcriptional regulator
IAI02_RS13720	COG2233	PERMEase
IAI02_RS13725	COG3729	General stress protein
IAI02_RS13760	COG3381	protein complex oligomerization
IAI02_RS13765	COG0243	molybdopterin cofactor binding
IAI02_RS13770	COG3005	denitrification pathway
IAI02_RS13775	COG0745	RESPONSE REGULATOR receiver
IAI02_RS13780	COG1879	ABC-type sugar transport system periplasmic component
IAI02_RS13785	COG0784	Response regulator, receiver
IAI02_RS13785	COG2205	protein histidine kinase activity
IAI02_RS13785	COG2198	Histidine kinase
IAI02_RS13790	COG0348	domain, Protein
IAI02_RS13810	COG1278	Cold shock
IAI02_RS13815	COG1278	Cold shock
IAI02_RS13835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAI02_RS13840	COG1596	polysaccharide export
IAI02_RS13845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAI02_RS13850	COG0489	protein tyrosine kinase activity
IAI02_RS13850	COG3206	protein involved in exopolysaccharide biosynthesis
IAI02_RS13865	COG1294	oxidase, subunit
IAI02_RS13870	COG1271	oxidase subunit
IAI02_RS13875	COG1773	rubredoxin
IAI02_RS13880	COG1999	signal sequence binding
IAI02_RS13885	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IAI02_RS13890	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IAI02_RS13895	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IAI02_RS13900	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IAI02_RS13910	COG0670	Belongs to the BI1 family
IAI02_RS13915	COG2920	part of a sulfur-relay system
IAI02_RS13920	COG1254	Belongs to the acylphosphatase family
IAI02_RS13935	COG1832	CoA-binding protein
IAI02_RS13950	COG0210	DNA helicase
IAI02_RS13955	COG3304	Inner membrane component domain
IAI02_RS13960	COG1289	transmembrane transporter activity
IAI02_RS13965	COG3070	regulator of competence-specific genes
IAI02_RS13975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IAI02_RS13975	COG2885	chlorophyll binding
IAI02_RS13985	COG1067	ATP-dependent peptidase activity
IAI02_RS13995	COG3130	regulation of translation
IAI02_RS14000	COG3009	Protein conserved in bacteria
IAI02_RS14005	COG3008	intermembrane lipid transfer
IAI02_RS14005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IAI02_RS14010	COG2995	paraquat-inducible protein a
IAI02_RS14015	COG0488	(ABC) transporter
IAI02_RS14025	COG3217	Mosc domain protein beta barrel domain protein
IAI02_RS14025	COG0633	Ferredoxin
IAI02_RS14040	COG3121	Chaperone
IAI02_RS14045	COG3539	Fimbrial protein
IAI02_RS14050	COG3539	Fimbrial protein
IAI02_RS14055	COG3539	Fimbrial protein
IAI02_RS14065	COG3121	Chaperone
IAI02_RS14070	COG3539	Fimbrial protein
IAI02_RS14075	COG0431	NADPH-dependent FMN reductase
IAI02_RS14080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAI02_RS14090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAI02_RS14095	COG1116	anion transmembrane transporter activity
IAI02_RS14100	COG0308	aminopeptidase N
IAI02_RS14125	COG1448	Aminotransferase
IAI02_RS14130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAI02_RS14135	COG3108	Peptidase M15
IAI02_RS14140	COG2989	Protein conserved in bacteria
IAI02_RS14150	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IAI02_RS14160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAI02_RS14165	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IAI02_RS14170	COG3173	Aminoglycoside phosphotransferase
IAI02_RS14185	COG3214	Protein conserved in bacteria
IAI02_RS14190	COG1663	tetraacyldisaccharide 4'-kinase activity
IAI02_RS14195	COG1132	(ABC) transporter
IAI02_RS14210	COG0539	negative regulation of cytoplasmic translation
IAI02_RS14220	COG0501	Belongs to the peptidase M48B family
IAI02_RS14235	COG2323	membrane
IAI02_RS14240	COG1944	ATP diphosphatase activity
IAI02_RS14245	COG2116	formate transmembrane transporter activity
IAI02_RS14250	COG1882	Formate acetyltransferase
IAI02_RS14255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAI02_RS14265	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAI02_RS14285	COG0531	amino acid
IAI02_RS14295	COG1335	isochorismatase
IAI02_RS14300	COG3302	dmso reductase anchor subunit
IAI02_RS14305	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS14310	COG0243	molybdopterin cofactor binding
IAI02_RS14320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAI02_RS14330	COG1674	ftsk spoiiie
IAI02_RS14330	COG1178	ABC-type Fe3 transport system permease component
IAI02_RS14335	COG1522	sequence-specific DNA binding
IAI02_RS14340	COG0492	ferredoxin-NADP+ reductase activity
IAI02_RS14345	COG4988	ABC transporter
IAI02_RS14350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAI02_RS14390	COG1278	Cold shock
IAI02_RS14395	COG1136	(ABC) transporter
IAI02_RS14395	COG0577	efflux transmembrane transporter activity
IAI02_RS14400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS14405	COG2990	Protein conserved in bacteria
IAI02_RS14410	COG3593	DNA synthesis involved in DNA repair
IAI02_RS14420	COG2431	L-lysine efflux transmembrane transporter activity
IAI02_RS14430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAI02_RS14435	COG0028	Belongs to the TPP enzyme family
IAI02_RS14440	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IAI02_RS14445	COG0702	epimerase
IAI02_RS14450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAI02_RS14455	COG3023	N-Acetylmuramoyl-L-alanine amidase
IAI02_RS14470	COG1126	abc transporter atp-binding protein
IAI02_RS14475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS14480	COG4215	(ABC) transporter
IAI02_RS14485	COG4160	amino acid transport
IAI02_RS14490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS14505	COG1177	transmembrane transport
IAI02_RS14510	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAI02_RS14515	COG3842	ATPase activity
IAI02_RS14520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IAI02_RS14535	COG0778	Nitroreductase
IAI02_RS14545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAI02_RS14560	COG3226	Transcriptional regulator
IAI02_RS14565	COG0738	Major facilitator superfamily
IAI02_RS14570	COG0561	phosphatase activity
IAI02_RS14580	COG2814	Major facilitator Superfamily
IAI02_RS14585	COG0671	phosphoesterase, PA-phosphatase related
IAI02_RS14590	COG1349	DNA-binding transcription factor activity
IAI02_RS14595	COG1686	Belongs to the peptidase S11 family
IAI02_RS14600	COG0625	glutathione transferase activity
IAI02_RS14605	COG2133	pyrroloquinoline quinone binding
IAI02_RS14620	COG2199	diguanylate cyclase activity
IAI02_RS14625	COG2200	EAL domain
IAI02_RS14630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAI02_RS14640	COG0747	negative chemotaxis
IAI02_RS14645	COG4172	Belongs to the ABC transporter superfamily
IAI02_RS14650	COG1446	asparaginase
IAI02_RS14655	COG0303	'Molybdopterin
IAI02_RS14660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAI02_RS14665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAI02_RS14670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAI02_RS14675	COG1882	Formate acetyltransferase
IAI02_RS14680	COG0561	phosphatase activity
IAI02_RS14690	COG0488	(ABC) transporter
IAI02_RS14695	COG1376	ErfK ybiS ycfS ynhG family protein
IAI02_RS14700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAI02_RS14705	COG1321	iron dependent repressor
IAI02_RS14715	COG2194	sulfuric ester hydrolase activity
IAI02_RS14720	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IAI02_RS14730	COG5006	permease, DMT superfamily
IAI02_RS14740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS14745	COG0765	amino acid transport
IAI02_RS14750	COG1126	abc transporter atp-binding protein
IAI02_RS14755	COG0668	transmembrane transport
IAI02_RS14770	COG4774	siderophore transport
IAI02_RS14780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAI02_RS14790	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IAI02_RS14795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAI02_RS14800	COG1199	ATP-dependent helicase activity
IAI02_RS14805	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IAI02_RS14810	COG0513	Belongs to the DEAD box helicase family
IAI02_RS14815	COG1309	transcriptional regulator
IAI02_RS14825	COG1131	(ABC) transporter
IAI02_RS14830	COG0842	Transport permease protein
IAI02_RS14835	COG0842	Transport permease protein
IAI02_RS14845	COG3568	Endonuclease Exonuclease Phosphatase
IAI02_RS14850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAI02_RS14855	COG0392	lysyltransferase activity
IAI02_RS14860	COG0670	Belongs to the BI1 family
IAI02_RS14865	COG0670	Belongs to the BI1 family
IAI02_RS14870	COG0314	molybdopterin synthase activity
IAI02_RS14875	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IAI02_RS14885	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAI02_RS14895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IAI02_RS14905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IAI02_RS14910	COG2226	methyltransferase
IAI02_RS14925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAI02_RS14930	COG1881	PFAM PEBP family protein
IAI02_RS14935	COG4677	pectinesterase activity
IAI02_RS14940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAI02_RS14945	COG0471	metal ion transport
IAI02_RS14950	COG2828	Protein conserved in bacteria
IAI02_RS14955	COG0583	DNA-binding transcription factor activity
IAI02_RS14965	COG0561	phosphatase activity
IAI02_RS14970	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IAI02_RS14975	COG4149	molybdate abc transporter
IAI02_RS14980	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAI02_RS14990	COG2005	Transcriptional regulator
IAI02_RS14990	COG3585	molybdate ion transport
IAI02_RS14995	COG1119	ATPase activity
IAI02_RS15000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAI02_RS15005	COG1085	galactose-1-phosphate uridylyltransferase
IAI02_RS15015	COG2017	converts alpha-aldose to the beta-anomer
IAI02_RS15025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAI02_RS15035	COG1230	cation diffusion facilitator family transporter
IAI02_RS15040	COG3201	nicotinamide mononucleotide transporter
IAI02_RS15085	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IAI02_RS15090	COG2885	chlorophyll binding
IAI02_RS15100	COG3064	Membrane
IAI02_RS15105	COG0848	biopolymer transport protein
IAI02_RS15110	COG0811	peptide transport
IAI02_RS15115	COG0824	Thioesterase
IAI02_RS15120	COG3790	cyd operon protein YbgE
IAI02_RS15125	COG4890	Cyd operon protein YbgT
IAI02_RS15130	COG1294	oxidase, subunit
IAI02_RS15135	COG1271	oxidase subunit
IAI02_RS15145	COG0383	alpha-mannosidase activity
IAI02_RS15150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS15150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS15150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS15155	COG2188	Transcriptional regulator
IAI02_RS15160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAI02_RS15170	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAI02_RS15175	COG0567	Dehydrogenase, E1 component
IAI02_RS15180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAI02_RS15185	COG1053	succinate dehydrogenase
IAI02_RS15190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IAI02_RS15195	COG2009	succinate dehydrogenase
IAI02_RS15205	COG0372	Belongs to the citrate synthase family
IAI02_RS15210	COG3539	Fimbrial protein
IAI02_RS15215	COG3188	usher protein
IAI02_RS15220	COG3121	Chaperone
IAI02_RS15225	COG3539	Fimbrial protein
IAI02_RS15230	COG3180	Ammonia monooxygenase
IAI02_RS15245	COG1984	allophanate hydrolase subunit 2
IAI02_RS15250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IAI02_RS15255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAI02_RS15260	COG3104	oligopeptide transport
IAI02_RS15265	COG0415	Belongs to the DNA photolyase family
IAI02_RS15270	COG3272	Protein of unknown function (DUF1722)
IAI02_RS15315	COG2205	protein histidine kinase activity
IAI02_RS15320	COG0745	RESPONSE REGULATOR receiver
IAI02_RS15330	COG1982	Orn Lys Arg decarboxylase major
IAI02_RS15335	COG0531	amino acid
IAI02_RS15355	COG0033	Phosphoglucomutase
IAI02_RS15360	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IAI02_RS15365	COG0596	Alpha beta hydrolase
IAI02_RS15375	COG0716	FMN binding
IAI02_RS15385	COG0735	belongs to the Fur family
IAI02_RS15405	COG1263	PTS System
IAI02_RS15405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS15405	COG2190	(PTS) system
IAI02_RS15415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAI02_RS15420	COG1940	carbohydrate kinase activity
IAI02_RS15420	COG1846	Transcriptional regulator
IAI02_RS15425	COG0647	UMP catabolic process
IAI02_RS15430	COG0367	asparagine synthase
IAI02_RS15470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAI02_RS15480	COG1702	phosphate starvation-inducible protein PhoH
IAI02_RS15490	COG4535	Mg2 and Co2 transporter CorC
IAI02_RS15495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IAI02_RS15500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAI02_RS15505	COG0765	amino acid transport
IAI02_RS15510	COG0765	amino acid transport
IAI02_RS15515	COG1126	abc transporter atp-binding protein
IAI02_RS15525	COG0443	Heat shock 70 kDa protein
IAI02_RS15530	COG2214	Heat shock protein DnaJ domain protein
IAI02_RS15540	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IAI02_RS15545	COG2214	Heat shock protein DnaJ domain protein
IAI02_RS15565	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IAI02_RS15570	COG2888	peptidyl-tyrosine sulfation
IAI02_RS15585	COG1466	dna polymerase III delta subunit
IAI02_RS15595	COG0406	alpha-ribazole phosphatase activity
IAI02_RS15600	COG0799	negative regulation of ribosome biogenesis
IAI02_RS15610	COG0768	penicillin binding
IAI02_RS15615	COG0772	Belongs to the SEDS family
IAI02_RS15620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IAI02_RS15625	COG1686	Belongs to the peptidase S11 family
IAI02_RS15640	COG0583	DNA-binding transcription factor activity
IAI02_RS15650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAI02_RS15655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAI02_RS15675	COG3069	C4-dicarboxylate transmembrane transporter activity
IAI02_RS15680	COG4565	transcriptional regulatory protein
IAI02_RS15685	COG3290	protein histidine kinase activity
IAI02_RS15690	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IAI02_RS15700	COG2301	Belongs to the HpcH HpaI aldolase family
IAI02_RS15705	COG3051	citrate lyase alpha subunit
IAI02_RS15720	COG0471	metal ion transport
IAI02_RS15725	COG3719	Belongs to the RNase T2 family
IAI02_RS15730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAI02_RS15735	COG1063	alcohol dehydrogenase
IAI02_RS15740	COG0589	response to stress
IAI02_RS15745	COG3634	alkyl hydroperoxide reductase activity
IAI02_RS15755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAI02_RS15760	COG0583	DNA-binding transcription factor activity
IAI02_RS15765	COG3969	phosphoadenosine phosphosulfate
IAI02_RS15770	COG1475	DNA binding
IAI02_RS15775	COG0436	Aminotransferase
IAI02_RS15780	COG0371	Dehydrogenase
IAI02_RS15785	COG2879	small protein
IAI02_RS15790	COG1966	Carbon starvation protein
IAI02_RS15795	COG2050	protein possibly involved in aromatic compounds catabolism
IAI02_RS15800	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS15805	COG1535	isochorismatase
IAI02_RS15805	COG3433	isochorismatase activity
IAI02_RS15810	COG1021	2,3-dihydroxybenzoate-AMP ligase
IAI02_RS15815	COG1169	isochorismate synthase
IAI02_RS15820	COG4592	Periplasmic binding protein
IAI02_RS15830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAI02_RS15835	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAI02_RS15840	COG1120	ATPase activity
IAI02_RS15845	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IAI02_RS15850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAI02_RS15850	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IAI02_RS15855	COG3251	PFAM MbtH domain protein
IAI02_RS15860	COG2382	esterase
IAI02_RS15865	COG4771	TonB-dependent receptor
IAI02_RS15870	COG2977	Belongs to the P-Pant transferase superfamily
IAI02_RS15875	COG3385	transposase activity
IAI02_RS15905	COG2315	Protein conserved in bacteria
IAI02_RS15910	COG0778	Nitroreductase
IAI02_RS15915	COG0668	transmembrane transport
IAI02_RS15920	COG1113	amino acid transport
IAI02_RS15925	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAI02_RS15930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS15935	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS15940	COG1538	Outer membrane efflux protein
IAI02_RS15945	COG0745	RESPONSE REGULATOR receiver
IAI02_RS15950	COG5002	protein histidine kinase activity
IAI02_RS15955	COG3501	Rhs element vgr protein
IAI02_RS15965	COG4104	PAAR repeat-containing protein
IAI02_RS15965	COG3209	COG3209 Rhs family protein
IAI02_RS15970	COG3209	COG3209 Rhs family protein
IAI02_RS15970	COG4104	PAAR repeat-containing protein
IAI02_RS15980	COG4372	Transposase
IAI02_RS15985	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS16020	COG3772	lysozyme
IAI02_RS16030	COG2207	Transcriptional regulator
IAI02_RS16035	COG3272	Protein of unknown function (DUF1722)
IAI02_RS16170	COG0582	viral genome integration into host DNA
IAI02_RS16180	COG2197	response regulator
IAI02_RS16185	COG3539	Fimbrial protein
IAI02_RS16190	COG3539	Fimbrial protein
IAI02_RS16195	COG3188	usher protein
IAI02_RS16205	COG3539	Fimbrial protein
IAI02_RS16215	COG2501	S4 domain
IAI02_RS16220	COG1988	membrane-bound metal-dependent
IAI02_RS16230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAI02_RS16240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAI02_RS16245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAI02_RS16250	COG0549	Belongs to the carbamate kinase family
IAI02_RS16260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAI02_RS16265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAI02_RS16270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IAI02_RS16275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAI02_RS16280	COG3257	ureidoglycine aminohydrolase activity
IAI02_RS16290	COG2233	PERMEase
IAI02_RS16300	COG1953	Uracil, thiamine, allantoin
IAI02_RS16305	COG2084	Dehydrogenase
IAI02_RS16310	COG3622	Belongs to the hyi family
IAI02_RS16315	COG3960	tartronate-semialdehyde synthase activity
IAI02_RS16320	COG1414	Transcriptional regulator
IAI02_RS16330	COG0583	DNA-binding transcription factor activity
IAI02_RS16350	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS16355	COG4372	Transposase
IAI02_RS16365	COG3209	COG3209 Rhs family protein
IAI02_RS16375	COG3209	COG3209 Rhs family protein
IAI02_RS16380	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IAI02_RS16385	COG4181	ATPase activity
IAI02_RS16390	COG2755	lipolytic protein G-D-S-L family
IAI02_RS16395	COG0300	oxidoreductase activity
IAI02_RS16400	COG3118	belongs to the thioredoxin family
IAI02_RS16405	COG0390	transport system, permease component
IAI02_RS16410	COG4619	ABC transporter
IAI02_RS16415	COG0330	HflC and HflK could
IAI02_RS16420	COG1585	Membrane protein implicated in regulation of membrane protease activity
IAI02_RS16425	COG0789	Transcriptional regulator
IAI02_RS16430	COG0531	amino acid
IAI02_RS16435	COG2066	Belongs to the glutaminase family
IAI02_RS16440	COG2217	Heavy metal translocating P-type atpase
IAI02_RS16445	COG3093	addiction module antidote protein HigA
IAI02_RS16450	COG3735	TraB family
IAI02_RS16455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAI02_RS16460	COG0737	Belongs to the 5'-nucleotidase family
IAI02_RS16465	COG2223	nitrite transmembrane transporter activity
IAI02_RS16470	COG4651	solute:proton antiporter activity
IAI02_RS16470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAI02_RS16475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS16510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAI02_RS16520	COG2832	Protein of unknown function (DUF454)
IAI02_RS16525	COG3923	Primosomal replication protein n
IAI02_RS16535	COG3264	Mechanosensitive ion channel
IAI02_RS16535	COG1196	nuclear chromosome segregation
IAI02_RS16555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS16560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAI02_RS16575	COG0110	maltose O-acetyltransferase activity
IAI02_RS16585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IAI02_RS16590	COG5507	3-demethylubiquinone-9 3-methyltransferase
IAI02_RS16600	COG3695	enzyme binding
IAI02_RS16605	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IAI02_RS16610	COG1946	Acyl-CoA thioesterase
IAI02_RS16615	COG0004	ammonium transporteR
IAI02_RS16620	COG0347	Belongs to the P(II) protein family
IAI02_RS16625	COG1132	(ABC) transporter
IAI02_RS16630	COG1132	(ABC) transporter
IAI02_RS16635	COG1522	sequence-specific DNA binding
IAI02_RS16645	COG4533	DNA binding
IAI02_RS16655	COG0824	Thioesterase
IAI02_RS16660	COG1555	photosystem II stabilization
IAI02_RS16665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAI02_RS16670	COG0776	regulation of translation
IAI02_RS16675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IAI02_RS16695	COG0271	Belongs to the BolA IbaG family
IAI02_RS16700	COG3056	Lipoprotein
IAI02_RS16705	COG2223	nitrite transmembrane transporter activity
IAI02_RS16710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAI02_RS16715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAI02_RS16720	COG1845	cytochrome c oxidase, subunit III
IAI02_RS16725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAI02_RS16735	COG2814	Major facilitator Superfamily
IAI02_RS16745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAI02_RS16750	COG0693	protein deglycase activity
IAI02_RS16765	COG0142	geranyltranstransferase activity
IAI02_RS16775	COG0667	Aldo Keto reductase
IAI02_RS16780	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAI02_RS16785	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IAI02_RS16800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAI02_RS16800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAI02_RS16810	COG4238	major outer membrane lipoprotein
IAI02_RS16815	COG3248	Nucleoside-binding outer membrane protein
IAI02_RS16820	COG1403	HNH endonuclease
IAI02_RS16825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAI02_RS16830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAI02_RS16835	COG1862	Preprotein translocase
IAI02_RS16855	COG0366	Alpha amylase catalytic
IAI02_RS16860	COG1113	amino acid transport
IAI02_RS16865	COG1114	Component of the transport system for branched-chain amino acids
IAI02_RS16870	COG5002	protein histidine kinase activity
IAI02_RS16875	COG0745	RESPONSE REGULATOR receiver
IAI02_RS16880	COG0420	3'-5' exonuclease activity
IAI02_RS16885	COG0419	ATPase involved in DNA repair
IAI02_RS16905	COG1940	carbohydrate kinase activity
IAI02_RS16930	COG4126	flavin adenine dinucleotide binding
IAI02_RS16950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAI02_RS16955	COG3706	GGDEF domain
IAI02_RS16965	COG1785	Belongs to the alkaline phosphatase family
IAI02_RS16980	COG1181	Belongs to the D-alanine--D-alanine ligase family
IAI02_RS17000	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IAI02_RS17005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAI02_RS17010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAI02_RS17030	COG0113	porphobilinogen synthase activity
IAI02_RS17035	COG2175	clavaminate synthase activity
IAI02_RS17045	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IAI02_RS17050	COG4521	taurine ABC transporter
IAI02_RS17055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAI02_RS17060	COG1215	transferase activity, transferring glycosyl groups
IAI02_RS17090	COG3122	Protein conserved in bacteria
IAI02_RS17095	COG2814	Major facilitator Superfamily
IAI02_RS17110	COG3971	2-oxopent-4-enoate hydratase activity
IAI02_RS17130	COG1414	Transcriptional regulator
IAI02_RS17135	COG1609	Transcriptional regulator
IAI02_RS17140	COG3250	beta-galactosidase activity
IAI02_RS17145	COG2223	nitrite transmembrane transporter activity
IAI02_RS17150	COG0110	maltose O-acetyltransferase activity
IAI02_RS17155	COG2807	transmembrane transport
IAI02_RS17165	COG0288	reversible hydration of carbon dioxide
IAI02_RS17170	COG0583	DNA-binding transcription factor activity
IAI02_RS17175	COG0402	S-adenosylhomocysteine deaminase activity
IAI02_RS17180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IAI02_RS17185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAI02_RS17190	COG2079	MmgE PrpD family protein
IAI02_RS17195	COG0372	Belongs to the citrate synthase family
IAI02_RS17200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IAI02_RS17205	COG3829	transcription factor binding
IAI02_RS17215	COG1280	lysine exporter protein (LysE YggA)
IAI02_RS17230	COG1064	alcohol dehydrogenase
IAI02_RS17240	COG0549	Belongs to the carbamate kinase family
IAI02_RS17255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAI02_RS17265	COG0666	response to abiotic stimulus
IAI02_RS17275	COG0583	DNA-binding transcription factor activity
IAI02_RS17285	COG2200	EAL domain
IAI02_RS17285	COG2771	luxR family
IAI02_RS17295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAI02_RS17320	COG1556	Lactate utilization protein
IAI02_RS17325	COG1139	Iron-sulfur cluster binding protein
IAI02_RS17330	COG0247	lactate metabolic process
IAI02_RS17335	COG2207	Transcriptional regulator
IAI02_RS17340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAI02_RS17350	COG3059	membrane
IAI02_RS17360	COG2207	Transcriptional regulator
IAI02_RS17360	COG3708	Transcriptional regulator
IAI02_RS17405	COG3188	usher protein
IAI02_RS17415	COG3121	Chaperone
IAI02_RS17420	COG0727	PFAM Uncharacterised protein family (UPF0153)
IAI02_RS17430	COG2080	2 iron, 2 sulfur cluster binding
IAI02_RS17435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IAI02_RS17440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAI02_RS17445	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IAI02_RS17450	COG0583	DNA-binding transcription factor activity
IAI02_RS17480	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IAI02_RS17495	COG0582	viral genome integration into host DNA
IAI02_RS17520	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAI02_RS17540	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAI02_RS17555	COG0454	-acetyltransferase
IAI02_RS17565	COG2161	toxin-antitoxin pair type II binding
IAI02_RS17585	COG1943	Transposase
IAI02_RS17590	COG0791	NLP P60 protein
IAI02_RS17600	COG3077	Addiction module antitoxin, RelB DinJ family
IAI02_RS17610	COG3034	peptidoglycan biosynthetic process
IAI02_RS17615	COG0121	glutamine amidotransferase
IAI02_RS17625	COG1960	acyl-CoA dehydrogenase activity
IAI02_RS17635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAI02_RS17640	COG5433	transposase activity
IAI02_RS17660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAI02_RS17670	COG2226	methyltransferase
IAI02_RS17680	COG0741	lytic transglycosylase activity
IAI02_RS17680	COG1388	LysM domain
IAI02_RS17695	COG0583	DNA-binding transcription factor activity
IAI02_RS17700	COG0656	L-ascorbic acid biosynthetic process
IAI02_RS17735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IAI02_RS17740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAI02_RS17745	COG2011	ABC-type metal ion transport system permease component
IAI02_RS17750	COG1464	Belongs to the NlpA lipoprotein family
IAI02_RS17760	COG1720	tRNA m6t6A37 methyltransferase activity
IAI02_RS17770	COG0791	NLP P60 protein
IAI02_RS17775	COG3015	lipoprotein NlpE involved in copper resistance
IAI02_RS17780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IAI02_RS17785	COG4681	YaeQ
IAI02_RS17795	COG4568	rho-dependent transcription termination
IAI02_RS17800	COG0037	tRNA processing
IAI02_RS17805	COG0346	lactoylglutathione lyase activity
IAI02_RS17810	COG1982	Orn Lys Arg decarboxylase major
IAI02_RS17820	COG0587	DNA-directed DNA polymerase activity
IAI02_RS17845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAI02_RS17850	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IAI02_RS17860	COG0750	zinc metalloprotease
IAI02_RS17865	COG0575	Belongs to the CDS family
IAI02_RS17870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAI02_RS17875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IAI02_RS17900	COG0024	Methionine aminopeptidase
IAI02_RS17915	COG1408	metallophosphoesterase
IAI02_RS17925	COG3835	regulator
IAI02_RS17930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAI02_RS17945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAI02_RS17950	COG2860	membrane
IAI02_RS17975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAI02_RS17980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAI02_RS17985	COG1120	ATPase activity
IAI02_RS17990	COG4774	siderophore transport
IAI02_RS17995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAI02_RS18000	COG1643	Atp-dependent helicase
IAI02_RS18005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IAI02_RS18015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAI02_RS18025	COG0617	tRNA 3'-terminal CCA addition
IAI02_RS18030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAI02_RS18055	COG5464	transposase or invertase
IAI02_RS18065	COG0726	polysaccharide deacetylase
IAI02_RS18070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS18075	COG0842	Transport permease protein
IAI02_RS18080	COG1131	(ABC) transporter
IAI02_RS18085	COG0288	reversible hydration of carbon dioxide
IAI02_RS18090	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IAI02_RS18095	COG4993	Dehydrogenase
IAI02_RS18100	COG2132	Multicopper oxidase
IAI02_RS18125	COG1049	propionate catabolic process, 2-methylcitrate cycle
IAI02_RS18130	COG3064	Membrane
IAI02_RS18135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAI02_RS18140	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAI02_RS18145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IAI02_RS18150	COG2186	Transcriptional regulator
IAI02_RS18155	COG1113	amino acid transport
IAI02_RS18160	COG3725	Membrane protein required for beta-lactamase induction
IAI02_RS18165	COG3023	N-Acetylmuramoyl-L-alanine amidase
IAI02_RS18170	COG0157	Belongs to the NadC ModD family
IAI02_RS18175	COG4969	Belongs to the N-Me-Phe pilin family
IAI02_RS18180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAI02_RS18185	COG1459	type II secretion system
IAI02_RS18200	COG0237	dephospho-CoA kinase activity
IAI02_RS18215	COG0494	nUDIX hydrolase
IAI02_RS18235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAI02_RS18240	COG0849	cell division
IAI02_RS18245	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAI02_RS18250	COG1181	Belongs to the D-alanine--D-alanine ligase family
IAI02_RS18265	COG0772	Belongs to the SEDS family
IAI02_RS18270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAI02_RS18280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAI02_RS18285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAI02_RS18290	COG0768	penicillin binding
IAI02_RS18295	COG3116	cell division
IAI02_RS18305	COG2001	Belongs to the MraZ family
IAI02_RS18310	COG1609	Transcriptional regulator
IAI02_RS18320	COG0440	acetolactate synthase activity
IAI02_RS18325	COG0028	Belongs to the TPP enzyme family
IAI02_RS18335	COG0583	DNA-binding transcription factor activity
IAI02_RS18350	COG0473	3-isopropylmalate dehydrogenase activity
IAI02_RS18365	COG2814	Major facilitator Superfamily
IAI02_RS18375	COG4533	DNA binding
IAI02_RS18380	COG4143	(ABC) transporter
IAI02_RS18385	COG1178	ABC-type Fe3 transport system permease component
IAI02_RS18390	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IAI02_RS18395	COG0586	Pfam SNARE associated Golgi protein
IAI02_RS18400	COG4977	sequence-specific DNA binding
IAI02_RS18405	COG1069	ribulokinase activity
IAI02_RS18410	COG2160	L-arabinose isomerase activity
IAI02_RS18415	COG0235	Class ii aldolase
IAI02_RS18420	COG0417	DNA replication proofreading
IAI02_RS18430	COG0564	pseudouridine synthase activity
IAI02_RS18450	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IAI02_RS18455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IAI02_RS18460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAI02_RS18485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAI02_RS18510	COG1064	alcohol dehydrogenase
IAI02_RS18515	COG3265	gluconokinase activity
IAI02_RS18520	COG1063	alcohol dehydrogenase
IAI02_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS18530	COG2610	gluconate transmembrane transporter activity
IAI02_RS18535	COG1609	Transcriptional regulator
IAI02_RS18540	COG0433	COG0433 Predicted ATPase
IAI02_RS18545	COG0795	lipopolysaccharide-transporting ATPase activity
IAI02_RS18550	COG0795	lipopolysaccharide-transporting ATPase activity
IAI02_RS18560	COG2927	DNA polymerase III (CHI subunit)
IAI02_RS18565	COG0525	valine-tRNA ligase activity
IAI02_RS18570	COG4269	membrane
IAI02_RS18575	COG0456	acetyltransferase
IAI02_RS18580	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IAI02_RS18595	COG2731	YhcH YjgK YiaL family protein
IAI02_RS18600	COG1309	transcriptional regulator
IAI02_RS18605	COG1028	Short-chain dehydrogenase reductase Sdr
IAI02_RS18610	COG0251	oxidation-reduction process
IAI02_RS18630	COG0251	oxidation-reduction process
IAI02_RS18635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IAI02_RS18645	COG1609	Transcriptional regulator
IAI02_RS18650	COG1263	PTS System
IAI02_RS18650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS18655	COG0366	Alpha amylase catalytic
IAI02_RS18660	COG1328	CTP reductase activity
IAI02_RS18665	COG0602	queuosine metabolic process
IAI02_RS18670	COG3783	Cytochrome b(562)
IAI02_RS18675	COG0312	modulator of DNA gyrase
IAI02_RS18685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAI02_RS18695	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS18700	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS18705	COG1129	ABC transporter
IAI02_RS18710	COG1879	ABC-type sugar transport system periplasmic component
IAI02_RS18715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IAI02_RS18720	COG2105	PFAM AIG2 family protein
IAI02_RS18725	COG2911	Protein conserved in bacteria
IAI02_RS18730	COG0729	surface antigen
IAI02_RS18740	COG1253	flavin adenine dinucleotide binding
IAI02_RS18750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IAI02_RS18755	COG1218	3'(2'),5'-bisphosphate nucleotidase
IAI02_RS18765	COG1733	regulation of RNA biosynthetic process
IAI02_RS18770	COG0702	epimerase
IAI02_RS18775	COG0697	spore germination
IAI02_RS18785	COG1113	amino acid transport
IAI02_RS18790	COG0545	Peptidyl-prolyl cis-trans isomerase
IAI02_RS18795	COG3061	Opacity-associated protein A
IAI02_RS18800	COG1309	transcriptional regulator
IAI02_RS18810	COG1024	Enoyl-CoA hydratase
IAI02_RS18815	COG4670	ketone body catabolic process
IAI02_RS18820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IAI02_RS18825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IAI02_RS18835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAI02_RS18845	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAI02_RS18885	COG3414	Phosphotransferase system galactitol-specific IIB component
IAI02_RS18890	COG3037	sugar-specific permease SgaT UlaA
IAI02_RS18905	COG1073	alpha beta
IAI02_RS18910	COG3650	response to hydrogen peroxide
IAI02_RS18920	COG1960	acyl-CoA dehydrogenase activity
IAI02_RS18925	COG0754	glutathionylspermidine amidase activity
IAI02_RS18930	COG5463	Belongs to the UPF0441 family
IAI02_RS18935	COG3766	membrane
IAI02_RS18945	COG1842	Phage shock protein A
IAI02_RS18950	COG3789	protein conserved in bacteria
IAI02_RS18955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAI02_RS18960	COG0557	exoribonuclease II activity
IAI02_RS18975	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IAI02_RS18980	COG0330	HflC and HflK could
IAI02_RS18985	COG0330	HflC and HflK could
IAI02_RS18990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAI02_RS19010	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAI02_RS19015	COG0802	atpase or kinase
IAI02_RS19020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAI02_RS19020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAI02_RS19025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAI02_RS19065	COG1511	domain protein
IAI02_RS19065	COG3264	Mechanosensitive ion channel
IAI02_RS19080	COG0531	amino acid
IAI02_RS19090	COG1053	succinate dehydrogenase
IAI02_RS19095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAI02_RS19110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAI02_RS19115	COG3040	lipid binding
IAI02_RS19120	COG2076	Multidrug Resistance protein
IAI02_RS19125	COG5510	response to toxic substance
IAI02_RS19130	COG5510	response to toxic substance
IAI02_RS19140	COG1509	lysine 2,3-aminomutase activity
IAI02_RS19165	COG0531	amino acid
IAI02_RS19170	COG3030	protein affecting phage T7 exclusion by the F plasmid
IAI02_RS19175	COG1027	Aspartate ammonia-lyase
IAI02_RS19180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IAI02_RS19190	COG4232	protein-disulfide reductase activity
IAI02_RS19195	COG1309	transcriptional regulator
IAI02_RS19205	COG3710	Transcriptional regulator
IAI02_RS19210	COG0531	amino acid
IAI02_RS19215	COG1982	Orn Lys Arg decarboxylase major
IAI02_RS19220	COG3104	oligopeptide transport
IAI02_RS19225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IAI02_RS19240	COG2388	GCN5-related N-acetyl-transferase
IAI02_RS19245	COG3592	Divergent 4Fe-4S mono-cluster
IAI02_RS19250	COG3290	protein histidine kinase activity
IAI02_RS19255	COG4565	transcriptional regulatory protein
IAI02_RS19260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IAI02_RS19265	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IAI02_RS19265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAI02_RS19270	COG3647	Membrane
IAI02_RS19290	COG1486	melibiose metabolic process
IAI02_RS19295	COG2169	Transcriptional regulator
IAI02_RS19300	COG1982	Orn Lys Arg decarboxylase major
IAI02_RS19305	COG2207	Transcriptional regulator
IAI02_RS19310	COG0531	amino acid
IAI02_RS19315	COG2194	sulfuric ester hydrolase activity
IAI02_RS19320	COG0745	RESPONSE REGULATOR receiver
IAI02_RS19325	COG0642	Histidine kinase
IAI02_RS19335	COG0477	Major facilitator Superfamily
IAI02_RS19350	COG2824	Alkylphosphonate utilization operon protein PhnA
IAI02_RS19355	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IAI02_RS19365	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IAI02_RS19375	COG2188	Transcriptional regulator
IAI02_RS19380	COG3624	Phosphonate C-P lyase system protein PhnG
IAI02_RS19385	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IAI02_RS19390	COG3626	phosphonate metabolism
IAI02_RS19400	COG4107	phosphonate C-P lyase system protein PhnK
IAI02_RS19405	COG4778	phosphonate C-P lyase system protein PhnL
IAI02_RS19410	COG3454	Phosphonate metabolism
IAI02_RS19415	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IAI02_RS19420	COG0456	acetyltransferase
IAI02_RS19425	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IAI02_RS19435	COG0698	ribose 5-phosphate isomerase
IAI02_RS19440	COG1737	Transcriptional regulator
IAI02_RS19445	COG1879	ABC-type sugar transport system periplasmic component
IAI02_RS19450	COG1129	ABC transporter
IAI02_RS19455	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS19460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAI02_RS19465	COG1940	carbohydrate kinase activity
IAI02_RS19470	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IAI02_RS19480	COG1566	PFAM secretion protein HlyD family protein
IAI02_RS19485	COG1289	transmembrane transporter activity
IAI02_RS19500	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IAI02_RS19505	COG1301	dicarboxylic acid transport
IAI02_RS19510	COG4235	cytochrome complex assembly
IAI02_RS19515	COG3088	subunit of a heme lyase
IAI02_RS19520	COG1138	Cytochrome C-type biogenesis protein
IAI02_RS19525	COG3301	Polysulphide reductase, NrfD
IAI02_RS19530	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS19535	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IAI02_RS19545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAI02_RS19550	COG3162	membrane
IAI02_RS19560	COG1357	PFAM Pentapeptide repeats (8 copies)
IAI02_RS19565	COG0025	NhaP-type Na H and K H
IAI02_RS19570	COG2252	PERMEase
IAI02_RS19575	COG0789	Transcriptional regulator
IAI02_RS19580	COG2207	Transcriptional regulator
IAI02_RS19595	COG0629	single-stranded DNA binding
IAI02_RS19600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IAI02_RS19605	COG2315	Protein conserved in bacteria
IAI02_RS19610	COG0432	Pfam Uncharacterised protein family UPF0047
IAI02_RS19625	COG1448	Aminotransferase
IAI02_RS19630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAI02_RS19635	COG0305	Participates in initiation and elongation during chromosome replication
IAI02_RS19640	COG0604	alcohol dehydrogenase
IAI02_RS19650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAI02_RS19660	COG0735	belongs to the Fur family
IAI02_RS19665	COG3237	CsbD-like
IAI02_RS19670	COG0534	Mate efflux family protein
IAI02_RS19680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IAI02_RS19725	COG3842	ATPase activity
IAI02_RS19730	COG2182	Extracellular solute-binding protein
IAI02_RS19735	COG1175	transmembrane transport
IAI02_RS19740	COG3833	ABC-type maltose transport systems, permease component
IAI02_RS19745	COG0477	Major facilitator Superfamily
IAI02_RS19745	COG2814	Major facilitator Superfamily
IAI02_RS19765	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAI02_RS19790	COG0527	aspartate kinase activity
IAI02_RS19800	COG1187	pseudouridine synthase activity
IAI02_RS19810	COG1283	sodium-dependent phosphate transmembrane transporter activity
IAI02_RS19815	COG0646	methionine synthase
IAI02_RS19815	COG1410	methionine synthase
IAI02_RS19820	COG1414	Transcriptional regulator
IAI02_RS19835	COG2224	Isocitrate lyase
IAI02_RS19840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IAI02_RS19850	COG0456	acetyltransferase
IAI02_RS19885	COG0151	Belongs to the GarS family
IAI02_RS19890	COG2204	response regulator
IAI02_RS19895	COG4191	Histidine kinase
IAI02_RS19900	COG3678	ATP-independent chaperone mediated protein folding
IAI02_RS19915	COG3068	Protein conserved in bacteria
IAI02_RS19950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAI02_RS19955	COG2104	thiamine diphosphate biosynthetic process
IAI02_RS19965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAI02_RS20015	COG0250	Participates in transcription elongation, termination and antitermination
IAI02_RS20020	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAI02_RS20055	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IAI02_RS20055	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IAI02_RS20060	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IAI02_RS20090	COG4206	TonB-dependent receptor
IAI02_RS20105	COG1309	transcriptional regulator
IAI02_RS20115	COG0583	DNA-binding transcription factor activity
IAI02_RS20130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAI02_RS20145	COG2194	sulfuric ester hydrolase activity
IAI02_RS20150	COG2207	Transcriptional regulator
IAI02_RS20155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS20160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAI02_RS20165	COG1882	Formate acetyltransferase
IAI02_RS20170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS20175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS20180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAI02_RS20180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS20180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS20185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAI02_RS20190	COG0371	Dehydrogenase
IAI02_RS20195	COG3738	Protein conserved in bacteria
IAI02_RS20200	COG0697	spore germination
IAI02_RS20210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAI02_RS20215	COG0527	aspartate kinase activity
IAI02_RS20215	COG0460	homoserine dehydrogenase
IAI02_RS20220	COG0626	cystathionine gamma-synthase activity
IAI02_RS20230	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IAI02_RS20240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAI02_RS20245	COG1609	Transcriptional regulator
IAI02_RS20250	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IAI02_RS20265	COG1575	Belongs to the MenA family. Type 1 subfamily
IAI02_RS20280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IAI02_RS20290	COG1494	fructose-1,6-bisphosphatase
IAI02_RS20295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAI02_RS20300	COG0589	response to stress
IAI02_RS20305	COG3691	Protein conserved in bacteria
IAI02_RS20310	COG3152	Membrane
IAI02_RS20330	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAI02_RS20345	COG3678	ATP-independent chaperone mediated protein folding
IAI02_RS20350	COG0745	RESPONSE REGULATOR receiver
IAI02_RS20355	COG2205	protein histidine kinase activity
IAI02_RS20360	COG2258	MOSC domain
IAI02_RS20370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAI02_RS20410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS20415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS20415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAI02_RS20420	COG1363	Peptidase, m42
IAI02_RS20425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAI02_RS20425	COG3711	transcriptional antiterminator
IAI02_RS20445	COG0437	4 iron, 4 sulfur cluster binding
IAI02_RS20450	COG2864	formate dehydrogenase
IAI02_RS20460	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAI02_RS20465	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAI02_RS20470	COG0456	acetyltransferase
IAI02_RS20485	COG1011	Hydrolase
IAI02_RS20490	COG1349	DNA-binding transcription factor activity
IAI02_RS20495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS20500	COG2084	Dehydrogenase
IAI02_RS20505	COG3684	Belongs to the aldolase LacD family
IAI02_RS20510	COG2942	2-epimerase
IAI02_RS20515	COG2017	converts alpha-aldose to the beta-anomer
IAI02_RS20525	COG1501	Belongs to the glycosyl hydrolase 31 family
IAI02_RS20530	COG2211	Major facilitator Superfamily
IAI02_RS20535	COG2211	Major facilitator Superfamily
IAI02_RS20540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IAI02_RS20545	COG2271	Major facilitator Superfamily
IAI02_RS20550	COG1082	Xylose isomerase domain protein TIM barrel
IAI02_RS20555	COG2188	Transcriptional regulator
IAI02_RS20560	COG1217	gtp-binding protein TYPA
IAI02_RS20565	COG0174	glutamine synthetase
IAI02_RS20570	COG3852	Histidine kinase
IAI02_RS20575	COG2204	response regulator
IAI02_RS20585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAI02_RS20590	COG3078	GTPase activator activity
IAI02_RS20600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAI02_RS20600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAI02_RS20605	COG0204	Acyl-transferase
IAI02_RS20610	COG5339	Protein conserved in bacteria
IAI02_RS20615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAI02_RS20620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAI02_RS20625	COG3084	Protein conserved in bacteria
IAI02_RS20630	COG0746	molybdenum cofactor guanylyltransferase activity
IAI02_RS20635	COG1763	Mo-molybdopterin cofactor biosynthetic process
IAI02_RS20665	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IAI02_RS20670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAI02_RS20675	COG1739	Uncharacterized protein family UPF0029
IAI02_RS20690	COG0183	Belongs to the thiolase family
IAI02_RS20695	COG0543	2 iron, 2 sulfur cluster binding
IAI02_RS20700	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IAI02_RS20705	COG0250	Participates in transcription elongation, termination and antitermination
IAI02_RS20710	COG0084	hydrolase, TatD family'
IAI02_RS20715	COG0805	protein transport
IAI02_RS20720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAI02_RS20725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAI02_RS20735	COG3165	ubiquinone biosynthetic process from chorismate
IAI02_RS20745	COG1322	Protein conserved in bacteria
IAI02_RS20750	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IAI02_RS20755	COG0412	Dienelactone hydrolase
IAI02_RS20765	COG0583	DNA-binding transcription factor activity
IAI02_RS20770	COG0697	spore germination
IAI02_RS20775	COG0561	phosphatase activity
IAI02_RS20780	COG2267	carboxylic ester hydrolase activity
IAI02_RS20785	COG1280	lysine exporter protein (LysE YggA)
IAI02_RS20790	COG1280	lysine exporter protein (LysE YggA)
IAI02_RS20795	COG0514	ATP-dependent DNA helicase (RecQ)
IAI02_RS20800	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IAI02_RS20805	COG2050	protein possibly involved in aromatic compounds catabolism
IAI02_RS20810	COG2962	Rard protein
IAI02_RS20820	COG0598	Magnesium transport protein CorA
IAI02_RS20825	COG3698	Phosphodiester glycosidase
IAI02_RS20830	COG0210	DNA helicase
IAI02_RS20835	COG1011	Hydrolase
IAI02_RS20845	COG3159	Protein conserved in bacteria
IAI02_RS20855	COG5567	small periplasmic lipoprotein
IAI02_RS20865	COG3072	Adenylate cyclase
IAI02_RS20875	COG1587	Uroporphyrinogen-III synthase
IAI02_RS20880	COG2959	enzyme of heme biosynthesis
IAI02_RS20885	COG3071	HemY protein
IAI02_RS20890	COG3119	arylsulfatase activity
IAI02_RS20895	COG0641	radical SAM
IAI02_RS20920	COG1113	amino acid transport
IAI02_RS20940	COG2244	polysaccharide biosynthetic process
IAI02_RS20945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAI02_RS20950	COG0456	acetyltransferase
IAI02_RS20955	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IAI02_RS20960	COG1088	dTDP-glucose 4,6-dehydratase activity
IAI02_RS20965	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IAI02_RS20970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IAI02_RS20975	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IAI02_RS20980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAI02_RS20985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IAI02_RS20995	COG3118	belongs to the thioredoxin family
IAI02_RS21010	COG0210	DNA helicase
IAI02_RS21015	COG3692	DNA binding
IAI02_RS21020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAI02_RS21030	COG0583	DNA-binding transcription factor activity
IAI02_RS21035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAI02_RS21045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAI02_RS21050	COG3978	acetolactate synthase activity
IAI02_RS21070	COG0606	chelatase, subunit chli
IAI02_RS21075	COG3085	chromosome segregation
IAI02_RS21115	COG2186	Transcriptional regulator
IAI02_RS21120	COG0477	Major facilitator Superfamily
IAI02_RS21125	COG1609	Transcriptional regulator
IAI02_RS21130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAI02_RS21135	COG1879	ABC-type sugar transport system periplasmic component
IAI02_RS21140	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAI02_RS21145	COG1129	ABC transporter
IAI02_RS21175	COG1522	sequence-specific DNA binding
IAI02_RS21180	COG0716	FMN binding
IAI02_RS21195	COG3312	ion transport
IAI02_RS21245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAI02_RS21250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAI02_RS21255	COG0573	inorganic phosphate transmembrane transporter activity
IAI02_RS21260	COG0581	inorganic phosphate transmembrane transporter activity
IAI02_RS21265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAI02_RS21270	COG0704	Plays a role in the regulation of phosphate uptake
IAI02_RS21275	COG3711	transcriptional antiterminator
IAI02_RS21280	COG1263	PTS System
IAI02_RS21280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAI02_RS21280	COG2190	(PTS) system
IAI02_RS21285	COG2723	6-phospho-beta-galactosidase activity
IAI02_RS21295	COG2382	esterase
IAI02_RS21300	COG0363	glucosamine-6-phosphate deaminase activity
IAI02_RS21305	COG3196	Protein conserved in bacteria
IAI02_RS21315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAI02_RS21320	COG2252	PERMEase
IAI02_RS21360	COG0488	(ABC) transporter
IAI02_RS21405	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS21425	COG0814	amino acid
IAI02_RS21475	COG3657	addiction module killer protein
IAI02_RS21645	COG3421	Type III restriction
IAI02_RS21650	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IAI02_RS21735	COG1192	Involved in chromosome partitioning
IAI02_RS21745	COG1192	Involved in chromosome partitioning
IAI02_RS21775	COG2026	Addiction module toxin, RelE StbE family
IAI02_RS21825	COG3173	Aminoglycoside phosphotransferase
IAI02_RS21910	COG2207	Transcriptional regulator
IAI02_RS21925	COG1192	Involved in chromosome partitioning
IAI02_RS22010	COG1475	DNA binding
IAI02_RS22085	COG3328	transposase activity
IAI02_RS22255	COG2805	Type II/IV secretion system protein
IAI02_RS22315	COG0741	lytic transglycosylase activity
IAI02_RS22330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAI02_RS22375	COG2268	Band 7 protein
IAI02_RS22495	COG2805	Type II/IV secretion system protein
IAI02_RS22720	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS22725	COG4372	Transposase
IAI02_RS22740	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS22745	COG4372	Transposase
IAI02_RS23045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAI02_RS23060	COG0741	lytic transglycosylase activity
IAI02_RS23155	COG2132	Multicopper oxidase
IAI02_RS23165	COG0739	heme binding
IAI02_RS23195	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAI02_RS23280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAI02_RS23290	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS23415	COG0431	NADPH-dependent FMN reductase
IAI02_RS23435	COG1121	(ABC) transporter
IAI02_RS23510	COG3300	MHYT domain
IAI02_RS23510	COG5001	Diguanylate cyclase
IAI02_RS23540	COG4221	oxidoreductase activity
IAI02_RS23575	COG4372	Transposase
IAI02_RS23580	COG3436	PFAM IS66 Orf2 family protein
IAI02_RS23640	COG0250	Participates in transcription elongation, termination and antitermination
IAI02_RS23690	COG3504	Conjugal transfer protein
IAI02_RS23750	COG1396	sequence-specific DNA binding
IAI02_RS23770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAI02_RS23775	COG1061	Type III restriction enzyme res subunit
IAI02_RS23780	COG1002	Type II restriction enzyme, methylase subunits
IAI02_RS23960	COG1475	DNA binding
IAI02_RS24170	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IAI02_RS24180	COG3039	Transposase