locus-tag	class	description
D3W51_RS00010	COG0592	DNA-directed DNA polymerase activity
D3W51_RS00020	COG0187	DNA topoisomerase II activity
D3W51_RS00025	COG3753	Protein conserved in bacteria
D3W51_RS00030	COG0561	phosphatase activity
D3W51_RS00040	COG2186	Transcriptional regulator
D3W51_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
D3W51_RS00050	COG0800	Aldolase
D3W51_RS00060	COG2271	Major facilitator Superfamily
D3W51_RS00065	COG0644	oxidoreductase
D3W51_RS00075	COG5645	(Lipo)protein
D3W51_RS00095	COG2188	Transcriptional regulator
D3W51_RS00110	COG2207	Transcriptional regulator
D3W51_RS00115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3W51_RS00120	COG3119	arylsulfatase activity
D3W51_RS00130	COG2149	membrane
D3W51_RS00140	COG0641	radical SAM
D3W51_RS00145	COG2814	Major facilitator Superfamily
D3W51_RS00160	COG0028	Belongs to the TPP enzyme family
D3W51_RS00165	COG0440	acetolactate synthase activity
D3W51_RS00170	COG2197	response regulator
D3W51_RS00175	COG3851	Histidine kinase
D3W51_RS00180	COG2271	Major facilitator Superfamily
D3W51_RS00185	COG2271	Major facilitator Superfamily
D3W51_RS00195	COG2252	PERMEase
D3W51_RS00215	COG1464	Belongs to the NlpA lipoprotein family
D3W51_RS00220	COG0697	spore germination
D3W51_RS00225	COG2814	Major facilitator Superfamily
D3W51_RS00240	COG2211	Major facilitator Superfamily
D3W51_RS00245	COG1501	Belongs to the glycosyl hydrolase 31 family
D3W51_RS00250	COG2982	Protein involved in outer membrane biogenesis
D3W51_RS00255	COG2233	PERMEase
D3W51_RS00260	COG0786	glutamate:sodium symporter activity
D3W51_RS00265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3W51_RS00270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3W51_RS00275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3W51_RS00285	COG0194	GDP metabolic process
D3W51_RS00295	COG2860	membrane
D3W51_RS00300	COG3645	SOS response
D3W51_RS00305	COG1561	YicC-like family, N-terminal region
D3W51_RS00330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3W51_RS00360	COG1519	Transferase
D3W51_RS00365	COG0859	PFAM glycosyl transferase family 9
D3W51_RS00370	COG0438	transferase activity, transferring glycosyl groups
D3W51_RS00375	COG0515	serine threonine protein kinase
D3W51_RS00385	COG0438	transferase activity, transferring glycosyl groups
D3W51_RS00390	COG1442	glycosyl transferase family 8
D3W51_RS00395	COG1442	glycosyl transferase family 8
D3W51_RS00400	COG3642	lipopolysaccharide core region biosynthetic process
D3W51_RS00410	COG0859	PFAM glycosyl transferase family 9
D3W51_RS00415	COG3307	-O-antigen
D3W51_RS00420	COG0859	PFAM glycosyl transferase family 9
D3W51_RS00425	COG0859	PFAM glycosyl transferase family 9
D3W51_RS00440	COG0156	8-amino-7-oxononanoate synthase activity
D3W51_RS00450	COG1216	Glycosyl transferase, family 2
D3W51_RS00455	COG2861	carbohydrate metabolic process
D3W51_RS00460	COG4942	peptidase
D3W51_RS00465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D3W51_RS00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3W51_RS00480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3W51_RS00495	COG1045	serine acetyltransferase
D3W51_RS00500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D3W51_RS00510	COG2186	Transcriptional regulator
D3W51_RS00515	COG1620	l-lactate permease
D3W51_RS00530	COG3722	fumarate hydratase activity
D3W51_RS00540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS00540	COG2213	PTS system mannitol-specific
D3W51_RS00550	COG3039	Transposase
D3W51_RS00560	COG0625	glutathione transferase activity
D3W51_RS00570	COG3276	selenocysteine insertion sequence binding
D3W51_RS00575	COG1454	alcohol dehydrogenase
D3W51_RS00580	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS00595	COG1566	PFAM secretion protein HlyD family protein
D3W51_RS00600	COG0583	DNA-binding transcription factor activity
D3W51_RS00605	COG3713	MltA-interacting MipA family protein
D3W51_RS00615	COG0235	Class ii aldolase
D3W51_RS00620	COG3623	hexulose-6-phosphate isomerase
D3W51_RS00625	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D3W51_RS00630	COG1070	Carbohydrate kinase
D3W51_RS00635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3W51_RS00640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D3W51_RS00645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3W51_RS00650	COG2731	YhcH YjgK YiaL family protein
D3W51_RS00660	COG1414	Transcriptional regulator
D3W51_RS00665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS00670	COG3977	Valine--pyruvate aminotransferase
D3W51_RS00675	COG0366	Alpha amylase catalytic
D3W51_RS00680	COG2992	FlgJ-related protein
D3W51_RS00685	COG2207	Transcriptional regulator
D3W51_RS00685	COG1609	Transcriptional regulator
D3W51_RS00690	COG4214	carbohydrate transport
D3W51_RS00695	COG1129	ABC transporter
D3W51_RS00700	COG4213	ABC transporter substrate-binding protein
D3W51_RS00710	COG1070	Carbohydrate kinase
D3W51_RS00715	COG4682	membrane
D3W51_RS00720	COG4682	membrane
D3W51_RS00725	COG3274	enterobacterial common antigen metabolic process
D3W51_RS00755	COG1278	Cold shock
D3W51_RS00760	COG2944	sequence-specific DNA binding
D3W51_RS00775	COG2885	chlorophyll binding
D3W51_RS00780	COG0243	molybdopterin cofactor binding
D3W51_RS00785	COG0456	acetyltransferase
D3W51_RS00790	COG2818	Glycosylase
D3W51_RS00795	COG5571	outer membrane autotransporter
D3W51_RS00800	COG2223	nitrite transmembrane transporter activity
D3W51_RS00805	COG2194	sulfuric ester hydrolase activity
D3W51_RS00815	COG0747	negative chemotaxis
D3W51_RS00820	COG0601	transmembrane transport
D3W51_RS00825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3W51_RS00830	COG0444	Belongs to the ABC transporter superfamily
D3W51_RS00835	COG4608	Belongs to the ABC transporter superfamily
D3W51_RS00840	COG0814	amino acid
D3W51_RS00850	COG2194	sulfuric ester hydrolase activity
D3W51_RS00875	COG1215	transferase activity, transferring glycosyl groups
D3W51_RS00880	COG1215	transferase activity, transferring glycosyl groups
D3W51_RS00885	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D3W51_RS00890	COG3118	belongs to the thioredoxin family
D3W51_RS00890	COG0457	Tetratricopeptide repeat
D3W51_RS00895	COG2200	EAL domain
D3W51_RS00895	COG2199	diguanylate cyclase activity
D3W51_RS00905	COG0612	Peptidase, M16
D3W51_RS00910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS00915	COG2200	EAL domain
D3W51_RS00920	COG2982	Protein involved in outer membrane biogenesis
D3W51_RS00925	COG0477	Major facilitator Superfamily
D3W51_RS00930	COG1295	ribonuclease BN
D3W51_RS00935	COG0583	DNA-binding transcription factor activity
D3W51_RS00940	COG2197	response regulator
D3W51_RS00950	COG1858	cytochrome C peroxidase
D3W51_RS00955	COG0076	glutamate decarboxylase activity
D3W51_RS00960	COG2207	Transcriptional regulator
D3W51_RS00965	COG2207	Transcriptional regulator
D3W51_RS00970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3W51_RS00975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3W51_RS00985	COG2771	luxR family
D3W51_RS00990	COG3247	response to pH
D3W51_RS01005	COG1285	pathogenesis
D3W51_RS01010	COG2197	response regulator
D3W51_RS01015	COG3065	identical protein binding
D3W51_RS01025	COG1393	Belongs to the ArsC family
D3W51_RS01030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3W51_RS01035	COG0640	Transcriptional regulator
D3W51_RS01045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3W51_RS01050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D3W51_RS01055	COG0339	signal peptide processing
D3W51_RS01065	COG3104	oligopeptide transport
D3W51_RS01070	COG0589	response to stress
D3W51_RS01080	COG0306	phosphate transporter
D3W51_RS01085	COG2081	HI0933 family
D3W51_RS01110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3W51_RS01115	COG1129	ABC transporter
D3W51_RS01115	COG0842	Transport permease protein
D3W51_RS01120	COG0842	Transport permease protein
D3W51_RS01125	COG5433	transposase activity
D3W51_RS01130	COG1413	lyase activity
D3W51_RS01140	COG3209	COG3209 Rhs family protein
D3W51_RS01150	COG1124	(ABC) transporter
D3W51_RS01155	COG0444	Belongs to the ABC transporter superfamily
D3W51_RS01160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3W51_RS01165	COG0601	transmembrane transport
D3W51_RS01170	COG0747	negative chemotaxis
D3W51_RS01175	COG2091	lysine biosynthetic process via aminoadipic acid
D3W51_RS01180	COG0628	permease
D3W51_RS01185	COG0477	Major facilitator Superfamily
D3W51_RS01195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D3W51_RS01205	COG2217	Heavy metal translocating P-type atpase
D3W51_RS01210	COG3714	YhhN family
D3W51_RS01220	COG3776	membrane
D3W51_RS01225	COG0742	ribosomal rna small subunit methyltransferase
D3W51_RS01230	COG0552	protein localization to endoplasmic reticulum
D3W51_RS01235	COG2884	Cell division ATP-binding protein ftsE
D3W51_RS01240	COG2177	Part of the ABC transporter FtsEX involved in
D3W51_RS01245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3W51_RS01250	COG0683	leucine binding
D3W51_RS01255	COG0456	acetyltransferase
D3W51_RS01260	COG0683	leucine binding
D3W51_RS01265	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3W51_RS01270	COG4177	L-phenylalanine transmembrane transporter activity
D3W51_RS01275	COG0411	ABC transporter
D3W51_RS01280	COG0410	ABC transporter
D3W51_RS01285	COG1653	transport
D3W51_RS01290	COG1175	transmembrane transport
D3W51_RS01295	COG0395	ABC-type sugar transport system, permease component
D3W51_RS01300	COG3842	ATPase activity
D3W51_RS01305	COG0584	glycerophosphoryl diester phosphodiesterase
D3W51_RS01315	COG0405	Gamma-glutamyltransferase
D3W51_RS01335	COG3157	Type VI secretion system effector, Hcp
D3W51_RS01340	COG1247	-acetyltransferase
D3W51_RS01345	COG0673	inositol 2-dehydrogenase activity
D3W51_RS01350	COG1741	Belongs to the pirin family
D3W51_RS01355	COG1609	Transcriptional regulator
D3W51_RS01360	COG3265	gluconokinase activity
D3W51_RS01365	COG2610	gluconate transmembrane transporter activity
D3W51_RS01370	COG2095	MarC family integral membrane protein
D3W51_RS01375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3W51_RS01400	COG0058	SHG alpha-glucan phosphorylase activity
D3W51_RS01410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D3W51_RS01425	COG1349	DNA-binding transcription factor activity
D3W51_RS01430	COG4650	regulator
D3W51_RS01435	COG1690	Belongs to the RtcB family
D3W51_RS01450	COG0058	SHG alpha-glucan phosphorylase activity
D3W51_RS01455	COG1640	4-alpha-glucanotransferase
D3W51_RS01460	COG2610	gluconate transmembrane transporter activity
D3W51_RS01470	COG1040	competence protein
D3W51_RS01480	COG5464	transposase or invertase
D3W51_RS01490	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D3W51_RS01495	COG1918	ferrous iron import across plasma membrane
D3W51_RS01500	COG2183	response to ionizing radiation
D3W51_RS01505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3W51_RS01525	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D3W51_RS01535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D3W51_RS01540	COG1011	Hydrolase
D3W51_RS01550	COG0494	nUDIX hydrolase
D3W51_RS01555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D3W51_RS01560	COG4972	Pilus assembly protein
D3W51_RS01565	COG3166	PFAM Fimbrial assembly family protein
D3W51_RS01580	COG4796	Type ii and iii secretion system protein
D3W51_RS01595	COG3266	domain, Protein
D3W51_RS01600	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D3W51_RS01605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3W51_RS01610	COG0546	phosphoglycolate phosphatase activity
D3W51_RS01615	COG0180	Tryptophanyl-tRNA synthetase
D3W51_RS01625	COG2188	Transcriptional regulator
D3W51_RS01635	COG3457	Alanine racemase
D3W51_RS01640	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D3W51_RS01660	COG0626	cystathionine gamma-synthase activity
D3W51_RS01665	COG2188	Transcriptional regulator
D3W51_RS01670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS01675	COG1082	Xylose isomerase domain protein TIM barrel
D3W51_RS01680	COG2222	sugar isomerase
D3W51_RS01685	COG0531	amino acid
D3W51_RS01700	COG2116	formate transmembrane transporter activity
D3W51_RS01705	COG2146	nitrite reductase [NAD(P)H] activity
D3W51_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3W51_RS01720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3W51_RS01730	COG2184	nucleotidyltransferase activity
D3W51_RS01735	COG0512	Glutamine amidotransferase of anthranilate synthase
D3W51_RS01740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3W51_RS01745	COG1289	transmembrane transporter activity
D3W51_RS01750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3W51_RS01755	COG1765	OsmC-like protein
D3W51_RS01760	COG3954	Phosphoribulokinase
D3W51_RS01770	COG0429	hydrolase of the alpha beta-hydrolase fold
D3W51_RS01775	COG0488	(ABC) transporter
D3W51_RS01790	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D3W51_RS01795	COG1047	Peptidyl-prolyl cis-trans
D3W51_RS01805	COG0545	Peptidyl-prolyl cis-trans isomerase
D3W51_RS01810	COG2964	Protein conserved in bacteria
D3W51_RS01850	COG3979	chitinase
D3W51_RS01855	COG2906	2 iron, 2 sulfur cluster binding
D3W51_RS01860	COG2193	ferroxidase activity
D3W51_RS01865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D3W51_RS01870	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
D3W51_RS01875	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
D3W51_RS01880	COG3156	type II secretion system protein K
D3W51_RS01885	COG4795	General secretion pathway protein
D3W51_RS01890	COG2165	general secretion pathway protein
D3W51_RS01895	COG2165	general secretion pathway protein
D3W51_RS01900	COG2165	general secretion pathway protein
D3W51_RS01905	COG1459	type II secretion system
D3W51_RS01910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3W51_RS01915	COG1450	Type ii and iii secretion system protein
D3W51_RS01920	COG3031	protein transport across the cell outer membrane
D3W51_RS01925	COG3267	Type II secretory pathway component ExeA
D3W51_RS01925	COG3409	Peptidoglycan-binding domain 1 protein
D3W51_RS01950	COG0089	rRNA binding
D3W51_RS02040	COG0201	protein transport
D3W51_RS02080	COG0789	Transcriptional regulator
D3W51_RS02085	COG3036	rescue of stalled ribosome
D3W51_RS02095	COG0569	domain protein
D3W51_RS02115	COG0758	DNA mediated transformation
D3W51_RS02125	COG0551	DNA topoisomerase type I activity
D3W51_RS02145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3W51_RS02185	COG1126	abc transporter atp-binding protein
D3W51_RS02190	COG0765	amino acid transport
D3W51_RS02195	COG4597	amino acid ABC transporter
D3W51_RS02200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS02210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3W51_RS02215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3W51_RS02220	COG1309	transcriptional regulator
D3W51_RS02230	COG2189	Belongs to the N(4) N(6)-methyltransferase family
D3W51_RS02240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3W51_RS02250	COG4145	pantothenate transmembrane transporter activity
D3W51_RS02255	COG3924	membrane
D3W51_RS02260	COG0439	Biotin carboxylase
D3W51_RS02265	COG0511	ligase activity, forming carbon-carbon bonds
D3W51_RS02270	COG0604	alcohol dehydrogenase
D3W51_RS02275	COG2200	EAL domain
D3W51_RS02275	COG2199	diguanylate cyclase activity
D3W51_RS02285	COG1077	Cell shape determining protein MreB Mrl
D3W51_RS02290	COG1792	Involved in formation and maintenance of cell shape
D3W51_RS02295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D3W51_RS02300	COG0424	maF-like protein
D3W51_RS02305	COG1530	ribonuclease E activity
D3W51_RS02310	COG3164	Protein of unknown function
D3W51_RS02315	COG0312	modulator of DNA gyrase
D3W51_RS02320	COG0583	DNA-binding transcription factor activity
D3W51_RS02340	COG2732	(Barnase) inhibitor
D3W51_RS02360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3W51_RS02365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3W51_RS02370	COG3105	Protein conserved in bacteria
D3W51_RS02375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D3W51_RS02390	COG0625	glutathione transferase activity
D3W51_RS02395	COG2969	positive regulation of protein catabolic process
D3W51_RS02400	COG3069	C4-dicarboxylate transmembrane transporter activity
D3W51_RS02430	COG2731	YhcH YjgK YiaL family protein
D3W51_RS02435	COG4804	nuclease activity
D3W51_RS02440	COG3539	Fimbrial protein
D3W51_RS02450	COG3188	usher protein
D3W51_RS02455	COG3121	Chaperone
D3W51_RS02460	COG3539	Fimbrial protein
D3W51_RS02465	COG0493	'glutamate synthase
D3W51_RS02470	COG0067	glutamate synthase
D3W51_RS02470	COG0069	glutamate synthase activity
D3W51_RS02470	COG0070	glutamate synthase
D3W51_RS02475	COG1242	4 iron, 4 sulfur cluster binding
D3W51_RS02480	COG5002	protein histidine kinase activity
D3W51_RS02480	COG2198	Histidine kinase
D3W51_RS02480	COG0784	Response regulator, receiver
D3W51_RS02485	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D3W51_RS02495	COG0515	serine threonine protein kinase
D3W51_RS02500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS02515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3W51_RS02520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D3W51_RS02525	COG1137	ATPase activity
D3W51_RS02530	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D3W51_RS02535	COG3117	lipopolysaccharide transmembrane transporter activity
D3W51_RS02540	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D3W51_RS02545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D3W51_RS02545	COG0517	IMP dehydrogenase activity
D3W51_RS02550	COG0530	calcium, potassium:sodium antiporter activity
D3W51_RS02555	COG1127	ABC transporter
D3W51_RS02560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D3W51_RS02565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D3W51_RS02570	COG2854	intermembrane phospholipid transfer
D3W51_RS02575	COG3113	response to antibiotic
D3W51_RS02580	COG5007	Belongs to the BolA IbaG family
D3W51_RS02590	COG3423	Transcriptional regulator
D3W51_RS02595	COG0142	geranyltranstransferase activity
D3W51_RS02610	COG0697	spore germination
D3W51_RS02620	COG2027	D-alanyl-D-alanine carboxypeptidase
D3W51_RS02625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3W51_RS02630	COG1534	Rna-binding protein
D3W51_RS02640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3W51_RS02645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D3W51_RS02655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3W51_RS02665	COG2194	sulfuric ester hydrolase activity
D3W51_RS02685	COG0195	Participates in both transcription termination and antitermination
D3W51_RS02725	COG0513	Belongs to the DEAD box helicase family
D3W51_RS02730	COG0814	amino acid
D3W51_RS02735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3W51_RS02740	COG0826	peptidase U32
D3W51_RS02745	COG0826	peptidase U32
D3W51_RS02750	COG3154	lipid carrier protein
D3W51_RS02755	COG3153	acetyltransferase
D3W51_RS02770	COG0693	protein deglycase activity
D3W51_RS02775	COG0702	epimerase
D3W51_RS02780	COG0701	Predicted permease
D3W51_RS02785	COG2823	Periplasmic or secreted lipoprotein
D3W51_RS02800	COG3107	peptidoglycan biosynthetic process
D3W51_RS02805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3W51_RS02810	COG3539	Fimbrial protein
D3W51_RS02820	COG3121	Chaperone
D3W51_RS02825	COG3539	Fimbrial protein
D3W51_RS02830	COG0363	glucosamine-6-phosphate deaminase activity
D3W51_RS02835	COG3716	PTS system mannose fructose sorbose family IID component
D3W51_RS02840	COG3715	PTS system
D3W51_RS02845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS02855	COG2222	sugar isomerase
D3W51_RS02860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3W51_RS02865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS02880	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS02890	COG1349	DNA-binding transcription factor activity
D3W51_RS02900	COG2002	toxin-antitoxin pair type II binding
D3W51_RS02905	COG2721	sulfolactate sulfo-lyase activity
D3W51_RS02910	COG2271	Major facilitator Superfamily
D3W51_RS02920	COG2084	Dehydrogenase
D3W51_RS02925	COG1929	Belongs to the glycerate kinase type-1 family
D3W51_RS02950	COG0583	DNA-binding transcription factor activity
D3W51_RS02955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3W51_RS02965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3W51_RS02970	COG1882	Formate acetyltransferase
D3W51_RS02975	COG0251	oxidation-reduction process
D3W51_RS02980	COG1760	l-serine dehydratase
D3W51_RS02985	COG0814	amino acid
D3W51_RS03000	COG1741	Belongs to the pirin family
D3W51_RS03005	COG0583	DNA-binding transcription factor activity
D3W51_RS03010	COG3152	Membrane
D3W51_RS03015	COG3152	Membrane
D3W51_RS03020	COG0435	Glutathione S-transferase
D3W51_RS03025	COG2259	Doxx family
D3W51_RS03035	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
D3W51_RS03040	COG4575	ribosome binding
D3W51_RS03045	COG1422	Protein of unknown function (DUF1090)
D3W51_RS03055	COG0586	Pfam SNARE associated Golgi protein
D3W51_RS03060	COG2186	Transcriptional regulator
D3W51_RS03065	COG2271	Major facilitator Superfamily
D3W51_RS03075	COG2721	sulfolactate sulfo-lyase activity
D3W51_RS03085	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D3W51_RS03090	COG0861	Integral membrane protein TerC family
D3W51_RS03095	COG0673	inositol 2-dehydrogenase activity
D3W51_RS03100	COG2949	membrane
D3W51_RS03105	COG1451	nucleotide metabolic process
D3W51_RS03115	COG4680	protein conserved in bacteria
D3W51_RS03120	COG5499	transcription regulator containing HTH domain
D3W51_RS03125	COG1902	pentaerythritol trinitrate reductase activity
D3W51_RS03125	COG0446	pyridine nucleotide-disulphide oxidoreductase
D3W51_RS03130	COG3408	Glycogen debranching enzyme
D3W51_RS03130	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
D3W51_RS03140	COG0531	amino acid
D3W51_RS03145	COG2731	YhcH YjgK YiaL family protein
D3W51_RS03150	COG3250	beta-galactosidase activity
D3W51_RS03155	COG1609	Transcriptional regulator
D3W51_RS03160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3W51_RS03170	COG0840	transmembrane signaling receptor activity
D3W51_RS03175	COG1695	Transcriptional regulator
D3W51_RS03180	COG2375	cellular response to nickel ion
D3W51_RS03195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3W51_RS03200	COG0358	DNA primase activity
D3W51_RS03205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3W51_RS03215	COG0471	metal ion transport
D3W51_RS03220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D3W51_RS03225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D3W51_RS03230	COG0583	DNA-binding transcription factor activity
D3W51_RS03240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3W51_RS03255	COG4991	sh3 domain protein
D3W51_RS03260	COG3025	triphosphatase activity
D3W51_RS03285	COG2268	Band 7 protein
D3W51_RS03290	COG1585	Membrane protein implicated in regulation of membrane protease activity
D3W51_RS03300	COG3539	Fimbrial protein
D3W51_RS03305	COG3121	Chaperone
D3W51_RS03315	COG3539	Fimbrial protein
D3W51_RS03320	COG2960	long-chain fatty acid transporting porin activity
D3W51_RS03335	COG3384	dioxygenase
D3W51_RS03340	COG0754	glutathionylspermidine amidase activity
D3W51_RS03350	COG1538	Outer membrane efflux protein
D3W51_RS03355	COG0494	nUDIX hydrolase
D3W51_RS03360	COG3151	Protein conserved in bacteria
D3W51_RS03365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3W51_RS03370	COG3150	esterase
D3W51_RS03375	COG0187	DNA topoisomerase II activity
D3W51_RS03380	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3W51_RS03385	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3W51_RS03395	COG0642	Histidine kinase
D3W51_RS03400	COG0745	RESPONSE REGULATOR receiver
D3W51_RS03405	COG3111	PFAM Bacterial OB fold (BOF) protein
D3W51_RS03410	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D3W51_RS03425	COG3039	Transposase
D3W51_RS03440	COG2944	sequence-specific DNA binding
D3W51_RS03445	COG4166	transmembrane transport
D3W51_RS03450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3W51_RS03455	COG0204	Acyl-transferase
D3W51_RS03460	COG2132	Multicopper oxidase
D3W51_RS03465	COG1032	radical SAM domain protein
D3W51_RS03470	COG4238	major outer membrane lipoprotein
D3W51_RS03480	COG0656	L-ascorbic acid biosynthetic process
D3W51_RS03485	COG1979	alcohol dehydrogenase
D3W51_RS03490	COG2207	Transcriptional regulator
D3W51_RS03495	COG0586	Pfam SNARE associated Golgi protein
D3W51_RS03500	COG0626	cystathionine gamma-synthase activity
D3W51_RS03505	COG0811	peptide transport
D3W51_RS03510	COG0848	biopolymer transport protein
D3W51_RS03515	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS03525	COG0667	Aldo Keto reductase
D3W51_RS03540	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
D3W51_RS03545	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS03550	COG5557	Pfam Polysulphide reductase, NrfD
D3W51_RS03555	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
D3W51_RS03560	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D3W51_RS03565	COG1773	rubredoxin
D3W51_RS03575	COG0298	carbon dioxide binding
D3W51_RS03580	COG0625	glutathione transferase activity
D3W51_RS03585	COG0754	glutathionylspermidine amidase activity
D3W51_RS03590	COG0306	phosphate transporter
D3W51_RS03595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3W51_RS03605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3W51_RS03610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3W51_RS03615	COG2244	polysaccharide biosynthetic process
D3W51_RS03625	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D3W51_RS03630	COG0795	lipopolysaccharide-transporting ATPase activity
D3W51_RS03640	COG0156	8-amino-7-oxononanoate synthase activity
D3W51_RS03645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3W51_RS03655	COG0318	PFAM AMP-dependent synthetase and ligase
D3W51_RS03660	COG0456	acetyltransferase
D3W51_RS03665	COG2186	Transcriptional regulator
D3W51_RS03670	COG0277	FAD linked oxidase domain protein
D3W51_RS03675	COG0277	FAD linked oxidase domain protein
D3W51_RS03680	COG0247	lactate metabolic process
D3W51_RS03685	COG3193	protein, possibly involved in utilization of glycolate and propanediol
D3W51_RS03690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D3W51_RS03695	COG1620	l-lactate permease
D3W51_RS03705	COG3064	Membrane
D3W51_RS03710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D3W51_RS03730	COG3031	protein transport across the cell outer membrane
D3W51_RS03740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3W51_RS03745	COG1459	type II secretion system
D3W51_RS03750	COG2165	general secretion pathway protein
D3W51_RS03780	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
D3W51_RS03790	COG1811	Na channel or pump
D3W51_RS03795	COG1982	Orn Lys Arg decarboxylase major
D3W51_RS03800	COG2211	Major facilitator Superfamily
D3W51_RS03815	COG1194	a g-specific adenine glycosylase
D3W51_RS03825	COG3171	Protein conserved in bacteria
D3W51_RS03835	COG0252	asparaginase activity
D3W51_RS03845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3W51_RS03850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3W51_RS03860	COG0762	integral membrane protein
D3W51_RS03865	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D3W51_RS03870	COG2805	Type II/IV secretion system protein
D3W51_RS03885	COG0189	ligase activity
D3W51_RS03890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3W51_RS03895	COG2356	endonuclease I
D3W51_RS03905	COG2814	Major facilitator Superfamily
D3W51_RS03930	COG1166	arginine decarboxylase activity
D3W51_RS03940	COG0501	Belongs to the peptidase M48B family
D3W51_RS03945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D3W51_RS03950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS03955	COG2213	PTS system mannitol-specific
D3W51_RS03960	COG1063	alcohol dehydrogenase
D3W51_RS03965	COG1494	fructose-1,6-bisphosphatase
D3W51_RS03970	COG3722	fumarate hydratase activity
D3W51_RS03975	COG1072	(Pantothenic acid kinase))
D3W51_RS03990	COG0191	fructose-bisphosphate aldolase activity
D3W51_RS03995	COG0668	transmembrane transport
D3W51_RS04000	COG1279	arginine transmembrane transporter activity
D3W51_RS04005	COG2968	Membrane
D3W51_RS04010	COG0583	DNA-binding transcription factor activity
D3W51_RS04015	COG0427	acetyl-CoA hydrolase
D3W51_RS04020	COG1024	Enoyl-CoA hydratase
D3W51_RS04025	COG1703	isobutyryl-CoA mutase activity
D3W51_RS04030	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D3W51_RS04030	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D3W51_RS04050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3W51_RS04060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3W51_RS04080	COG0006	proline dipeptidase activity
D3W51_RS04085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3W51_RS04090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3W51_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS04120	COG2723	6-phospho-beta-galactosidase activity
D3W51_RS04130	COG1272	protein, Hemolysin III
D3W51_RS04140	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D3W51_RS04150	COG0716	FMN binding
D3W51_RS04155	COG4974	Belongs to the 'phage' integrase family
D3W51_RS04160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3W51_RS04165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3W51_RS04175	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3W51_RS04195	COG2233	PERMEase
D3W51_RS04200	COG0493	'glutamate synthase
D3W51_RS04200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS04205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS04210	COG2252	PERMEase
D3W51_RS04215	COG0402	S-adenosylhomocysteine deaminase activity
D3W51_RS04220	COG2233	PERMEase
D3W51_RS04225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3W51_RS04225	COG2080	2 iron, 2 sulfur cluster binding
D3W51_RS04230	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3W51_RS04235	COG0402	S-adenosylhomocysteine deaminase activity
D3W51_RS04240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS04240	COG0493	'glutamate synthase
D3W51_RS04245	COG2068	MobA-Related Protein
D3W51_RS04250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3W51_RS04255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D3W51_RS04255	COG3608	succinylglutamate desuccinylase aspartoacylase
D3W51_RS04260	COG0549	Belongs to the carbamate kinase family
D3W51_RS04270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3W51_RS04275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3W51_RS04280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D3W51_RS04285	COG3829	transcription factor binding
D3W51_RS04290	COG2080	2 iron, 2 sulfur cluster binding
D3W51_RS04295	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3W51_RS04300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3W51_RS04305	COG4942	peptidase
D3W51_RS04430	COG3710	Transcriptional regulator
D3W51_RS04430	COG0457	Tetratricopeptide repeat
D3W51_RS04435	COG0457	Tetratricopeptide repeat
D3W51_RS04460	COG3710	Transcriptional regulator
D3W51_RS04465	COG2771	luxR family
D3W51_RS04470	COG0814	amino acid
D3W51_RS04475	COG0183	Belongs to the thiolase family
D3W51_RS04485	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS04490	COG2814	Major facilitator Superfamily
D3W51_RS04495	COG1794	racemase activity, acting on amino acids and derivatives
D3W51_RS04500	COG0583	DNA-binding transcription factor activity
D3W51_RS04510	COG1609	Transcriptional regulator
D3W51_RS04525	COG0667	Aldo Keto reductase
D3W51_RS04535	COG0861	Integral membrane protein TerC family
D3W51_RS04555	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
D3W51_RS04570	COG2165	general secretion pathway protein
D3W51_RS04575	COG4795	General secretion pathway protein
D3W51_RS04585	COG4967	type IV pilus modification protein PilV
D3W51_RS04590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D3W51_RS04595	COG1025	Belongs to the peptidase M16 family
D3W51_RS04600	COG1074	ATP-dependent DNA helicase activity
D3W51_RS04605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3W51_RS04610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D3W51_RS04610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D3W51_RS04615	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3W51_RS04635	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D3W51_RS04640	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D3W51_RS04645	COG2166	iron-sulfur cluster assembly
D3W51_RS04650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3W51_RS04660	COG0583	DNA-binding transcription factor activity
D3W51_RS04665	COG2363	Small membrane protein
D3W51_RS04675	COG1349	DNA-binding transcription factor activity
D3W51_RS04685	COG1070	Carbohydrate kinase
D3W51_RS04695	COG0738	Major facilitator superfamily
D3W51_RS04700	COG0235	Class ii aldolase
D3W51_RS04705	COG1454	alcohol dehydrogenase
D3W51_RS04715	COG1760	l-serine dehydratase
D3W51_RS04720	COG0814	amino acid
D3W51_RS04725	COG1611	Belongs to the LOG family
D3W51_RS04740	COG3098	single-species biofilm formation
D3W51_RS04745	COG0564	pseudouridine synthase activity
D3W51_RS04750	COG0716	FMN binding
D3W51_RS04755	COG2271	Major facilitator Superfamily
D3W51_RS04760	COG4948	Mandelate Racemase Muconate Lactonizing
D3W51_RS04765	COG4948	Mandelate Racemase Muconate Lactonizing
D3W51_RS04770	COG4999	Histidine kinase
D3W51_RS04770	COG3850	Histidine kinase
D3W51_RS04770	COG2205	protein histidine kinase activity
D3W51_RS04770	COG3437	response regulator, receiver
D3W51_RS04775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3W51_RS04780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3W51_RS04785	COG2336	PFAM SpoVT AbrB
D3W51_RS04790	COG2337	Toxic component of a toxin-antitoxin (TA) module
D3W51_RS04795	COG3956	TIGRFAM MazG family protein
D3W51_RS04810	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D3W51_RS04820	COG0602	queuosine metabolic process
D3W51_RS04825	COG1070	Carbohydrate kinase
D3W51_RS04830	COG2223	nitrite transmembrane transporter activity
D3W51_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS04840	COG0277	FAD linked oxidase domain protein
D3W51_RS04845	COG0477	Major facilitator Superfamily
D3W51_RS04850	COG2086	electron transfer activity
D3W51_RS04855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D3W51_RS04860	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D3W51_RS04865	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D3W51_RS04870	COG0644	oxidoreductase
D3W51_RS04875	COG0720	synthase
D3W51_RS04885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3W51_RS04905	COG3385	transposase activity
D3W51_RS04910	COG2433	Pfam Transposase IS66
D3W51_RS04915	COG3436	PFAM IS66 Orf2 family protein
D3W51_RS04925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3W51_RS04930	COG1518	maintenance of DNA repeat elements
D3W51_RS04945	COG1857	crispr-associated protein
D3W51_RS04960	COG1203	CRISPR-associated helicase, Cas3
D3W51_RS04965	COG3385	transposase activity
D3W51_RS04970	COG2234	aminopeptidase activity
D3W51_RS05025	COG4942	peptidase
D3W51_RS05025	COG1388	LysM domain
D3W51_RS05030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3W51_RS05035	COG2610	gluconate transmembrane transporter activity
D3W51_RS05040	COG3622	Belongs to the hyi family
D3W51_RS05045	COG0235	Class ii aldolase
D3W51_RS05055	COG2084	Dehydrogenase
D3W51_RS05060	COG1349	DNA-binding transcription factor activity
D3W51_RS05065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D3W51_RS05080	COG3604	Transcriptional regulator
D3W51_RS05085	COG0309	Hydrogenase expression formation protein (HypE)
D3W51_RS05090	COG0409	Hydrogenase expression formation protein
D3W51_RS05095	COG0298	carbon dioxide binding
D3W51_RS05100	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D3W51_RS05105	COG0375	protein maturation
D3W51_RS05115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS05120	COG0651	ATP synthesis coupled electron transport
D3W51_RS05125	COG0650	Formate hydrogenlyase subunit 4
D3W51_RS05130	COG3261	NADH dehydrogenase
D3W51_RS05130	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
D3W51_RS05135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3W51_RS05140	COG3260	NADH ubiquinone oxidoreductase 20
D3W51_RS05150	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D3W51_RS05155	COG2723	6-phospho-beta-galactosidase activity
D3W51_RS05160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS05160	COG1263	PTS System
D3W51_RS05165	COG1609	Transcriptional regulator
D3W51_RS05170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS05175	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
D3W51_RS05195	COG0517	IMP dehydrogenase activity
D3W51_RS05195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D3W51_RS05200	COG1349	DNA-binding transcription factor activity
D3W51_RS05205	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS05215	COG3731	PTS system glucitol sorbitol-specific IIA component
D3W51_RS05220	COG3732	PTS system glucitol sorbitol-specific
D3W51_RS05225	COG3730	PTS system glucitol sorbitol-specific
D3W51_RS05230	COG2951	lytic endotransglycosylase activity
D3W51_RS05235	COG1546	Belongs to the CinA family
D3W51_RS05255	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D3W51_RS05285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3W51_RS05290	COG1238	metal cluster binding
D3W51_RS05305	COG2814	Major facilitator Superfamily
D3W51_RS05310	COG1566	PFAM secretion protein HlyD family protein
D3W51_RS05315	COG1846	Transcriptional regulator
D3W51_RS05325	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D3W51_RS05330	COG2814	Major facilitator Superfamily
D3W51_RS05335	COG2113	Glycine betaine
D3W51_RS05340	COG4176	ABC-type proline glycine betaine transport system permease component
D3W51_RS05345	COG4175	Glycine betaine
D3W51_RS05355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3W51_RS05360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3W51_RS05370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3W51_RS05375	COG4575	ribosome binding
D3W51_RS05390	COG2916	Histone family protein nucleoid-structuring protein H-NS
D3W51_RS05395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3W51_RS05400	COG0640	Transcriptional regulator
D3W51_RS05405	COG0401	homolog of Blt101
D3W51_RS05410	COG1652	LysM domain
D3W51_RS05415	COG1802	Transcriptional regulator
D3W51_RS05420	COG1113	amino acid transport
D3W51_RS05425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3W51_RS05430	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS05435	COG0579	oxidoreductase
D3W51_RS05450	COG0366	Alpha amylase catalytic
D3W51_RS05475	COG2867	negative regulation of translational initiation
D3W51_RS05485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3W51_RS05490	COG0497	DNA recombination
D3W51_RS05510	COG4536	flavin adenine dinucleotide binding
D3W51_RS05515	COG4137	Cytochrome C assembly protein
D3W51_RS05520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3W51_RS05545	COG2885	chlorophyll binding
D3W51_RS05575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D3W51_RS05580	COG0287	Prephenate dehydrogenase
D3W51_RS05580	COG1605	Chorismate mutase
D3W51_RS05585	COG0077	Prephenate dehydratase
D3W51_RS05585	COG1605	Chorismate mutase
D3W51_RS05595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3W51_RS05600	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3W51_RS05605	COG0564	pseudouridine synthase activity
D3W51_RS05610	COG1496	oxidoreductase activity
D3W51_RS05615	COG0542	response to heat
D3W51_RS05640	COG0477	Major facilitator Superfamily
D3W51_RS05645	COG5544	Lipoprotein
D3W51_RS05650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3W51_RS05655	COG0045	succinate-CoA ligase (ADP-forming) activity
D3W51_RS05655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3W51_RS05655	COG1042	CoA-binding domain protein
D3W51_RS05660	COG3148	PFAM DTW domain containing protein
D3W51_RS05665	COG3118	belongs to the thioredoxin family
D3W51_RS05670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3W51_RS05690	COG0583	DNA-binding transcription factor activity
D3W51_RS05695	COG0513	Belongs to the DEAD box helicase family
D3W51_RS05705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D3W51_RS05715	COG1595	DNA-templated transcription, initiation
D3W51_RS05720	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
D3W51_RS05725	COG3026	antisigma factor binding
D3W51_RS05730	COG3086	response to oxidative stress
D3W51_RS05740	COG0681	Belongs to the peptidase S26 family
D3W51_RS05760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D3W51_RS05775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS05780	COG1737	Transcriptional regulator
D3W51_RS05785	COG0560	Phosphoserine phosphatase
D3W51_RS05800	COG0047	phosphoribosylformylglycinamidine synthase activity
D3W51_RS05800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3W51_RS05805	COG2205	protein histidine kinase activity
D3W51_RS05810	COG3170	Tfp pilus assembly protein FimV
D3W51_RS05815	COG2204	response regulator
D3W51_RS05820	COG0347	Belongs to the P(II) protein family
D3W51_RS05825	COG1017	nitric oxide dioxygenase activity
D3W51_RS05825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3W51_RS05835	COG1940	carbohydrate kinase activity
D3W51_RS05840	COG0457	Tetratricopeptide repeat
D3W51_RS05845	COG1879	ABC-type sugar transport system periplasmic component
D3W51_RS05850	COG1129	ABC transporter
D3W51_RS05855	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3W51_RS05860	COG1063	alcohol dehydrogenase
D3W51_RS05865	COG2017	converts alpha-aldose to the beta-anomer
D3W51_RS05870	COG2259	Doxx family
D3W51_RS05895	COG4638	Rieske (2fe-2S)
D3W51_RS05900	COG0583	DNA-binding transcription factor activity
D3W51_RS05905	COG2814	Major facilitator Superfamily
D3W51_RS05910	COG3711	transcriptional antiterminator
D3W51_RS05915	COG1073	alpha beta
D3W51_RS05920	COG0483	inositol monophosphate 1-phosphatase activity
D3W51_RS05940	COG0822	iron-sulfur transferase activity
D3W51_RS05960	COG0633	Ferredoxin
D3W51_RS05965	COG2975	iron-sulfur cluster assembly
D3W51_RS05980	COG2897	thiosulfate sulfurtransferase activity
D3W51_RS05985	COG2373	Large extracellular alpha-helical protein
D3W51_RS05990	COG4953	penicillin-binding protein 1C
D3W51_RS06020	COG2976	Protein conserved in bacteria
D3W51_RS06035	COG1645	bacterial-type flagellum-dependent swarming motility
D3W51_RS06045	COG0517	IMP dehydrogenase activity
D3W51_RS06045	COG0516	GMP reductase activity
D3W51_RS06060	COG3133	Outer membrane lipoprotein
D3W51_RS06070	COG2200	EAL domain
D3W51_RS06075	COG0248	Ppx GppA phosphatase
D3W51_RS06080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D3W51_RS06085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D3W51_RS06100	COG2233	PERMEase
D3W51_RS06110	COG1393	Belongs to the ArsC family
D3W51_RS06115	COG4783	chaperone-mediated protein folding
D3W51_RS06120	COG0628	permease
D3W51_RS06130	COG3604	Transcriptional regulator
D3W51_RS06140	COG3260	NADH ubiquinone oxidoreductase 20
D3W51_RS06145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3W51_RS06150	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
D3W51_RS06150	COG3261	NADH dehydrogenase
D3W51_RS06155	COG0651	ATP synthesis coupled electron transport
D3W51_RS06165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3W51_RS06170	COG0650	Formate hydrogenlyase subunit 4
D3W51_RS06175	COG0651	ATP synthesis coupled electron transport
D3W51_RS06180	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS06185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3W51_RS06190	COG2716	regulation of RNA biosynthetic process
D3W51_RS06200	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D3W51_RS06210	COG2321	neutral zinc metallopeptidase
D3W51_RS06215	COG1444	tRNA N-acetyltransferase activity
D3W51_RS06220	COG0400	carboxylic ester hydrolase activity
D3W51_RS06235	COG1393	Belongs to the ArsC family
D3W51_RS06245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3W51_RS06250	COG3850	Histidine kinase
D3W51_RS06255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS06255	COG0493	'glutamate synthase
D3W51_RS06265	COG5342	invasion associated locus B
D3W51_RS06270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D3W51_RS06275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3W51_RS06280	COG0280	phosphate acetyltransferase
D3W51_RS06280	COG0281	malic enzyme
D3W51_RS06285	COG4810	utilization protein
D3W51_RS06290	COG4917	ethanolamine utilization protein
D3W51_RS06295	COG4766	ethanolamine catabolic process
D3W51_RS06300	COG4812	Cobalamin adenosyltransferase
D3W51_RS06305	COG0280	phosphate acetyltransferase
D3W51_RS06310	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D3W51_RS06315	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
D3W51_RS06320	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS06325	COG4820	ethanolamine utilization protein (EutJ)
D3W51_RS06330	COG1454	alcohol dehydrogenase
D3W51_RS06335	COG3192	ethanolamine utilization protein
D3W51_RS06340	COG4819	ethanolamine utilization protein
D3W51_RS06345	COG4303	Ethanolamine ammonia lyase large subunit
D3W51_RS06355	COG4816	utilization protein
D3W51_RS06360	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D3W51_RS06365	COG2207	Transcriptional regulator
D3W51_RS06375	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3W51_RS06380	COG0456	acetyltransferase
D3W51_RS06395	COG2837	iron assimilation
D3W51_RS06400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3W51_RS06405	COG1263	PTS System
D3W51_RS06405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS06425	COG4150	thiosulfate binding
D3W51_RS06430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D3W51_RS06435	COG4208	sulfate ABC transporter
D3W51_RS06440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D3W51_RS06445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3W51_RS06450	COG4884	unkown
D3W51_RS06450	COG3831	ATPase activity
D3W51_RS06465	COG2190	(PTS) system
D3W51_RS06470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3W51_RS06475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS06480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3W51_RS06500	COG3530	Putative quorum-sensing-regulated virulence factor
D3W51_RS06505	COG0385	Bile acid
D3W51_RS06510	COG0583	DNA-binding transcription factor activity
D3W51_RS06520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D3W51_RS06525	COG2211	Major facilitator Superfamily
D3W51_RS06535	COG0583	DNA-binding transcription factor activity
D3W51_RS06570	COG3415	Transposase
D3W51_RS06575	COG3415	Transposase
D3W51_RS06590	COG2199	diguanylate cyclase activity
D3W51_RS06590	COG2200	EAL domain
D3W51_RS06595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3W51_RS06620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS06625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS06630	COG0006	proline dipeptidase activity
D3W51_RS06635	COG1363	Peptidase, m42
D3W51_RS06640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3W51_RS06640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS06640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS06645	COG2207	Transcriptional regulator
D3W51_RS06650	COG3279	Response regulator of the LytR AlgR family
D3W51_RS06655	COG3275	phosphorelay sensor kinase activity
D3W51_RS06660	COG0436	Aminotransferase
D3W51_RS06670	COG1560	Kdo2-lipid A biosynthetic process
D3W51_RS06695	COG0028	Belongs to the TPP enzyme family
D3W51_RS06700	COG0679	Auxin Efflux Carrier
D3W51_RS06705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D3W51_RS06710	COG0784	Response regulator, receiver
D3W51_RS06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS06710	COG2198	Histidine kinase
D3W51_RS06710	COG2205	protein histidine kinase activity
D3W51_RS06715	COG2197	response regulator
D3W51_RS06720	COG1566	PFAM secretion protein HlyD family protein
D3W51_RS06725	COG0477	Major facilitator Superfamily
D3W51_RS06735	COG2610	gluconate transmembrane transporter activity
D3W51_RS06740	COG0583	DNA-binding transcription factor activity
D3W51_RS06775	COG0463	Glycosyl transferase, family 2
D3W51_RS06780	COG2246	polysaccharide biosynthetic process
D3W51_RS06785	COG0582	viral genome integration into host DNA
D3W51_RS06795	COG2116	formate transmembrane transporter activity
D3W51_RS06800	COG2853	Lipoprotein
D3W51_RS06810	COG2067	long-chain fatty acid transport protein
D3W51_RS06815	COG3691	Protein conserved in bacteria
D3W51_RS06830	COG2062	phosphohistidine phosphatase, SixA
D3W51_RS06835	COG3539	Fimbrial protein
D3W51_RS06840	COG3188	usher protein
D3W51_RS06845	COG3121	Chaperone
D3W51_RS06850	COG3539	Fimbrial protein
D3W51_RS06855	COG3539	Fimbrial protein
D3W51_RS06860	COG3539	Fimbrial protein
D3W51_RS06875	COG2890	protein-(glutamine-N5) methyltransferase activity
D3W51_RS06890	COG0730	response to heat
D3W51_RS06895	COG3101	peptidyl-lysine hydroxylation
D3W51_RS06910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3W51_RS06915	COG2814	Major facilitator Superfamily
D3W51_RS06930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3W51_RS06940	COG0586	Pfam SNARE associated Golgi protein
D3W51_RS06950	COG0285	dihydrofolate synthase activity
D3W51_RS06955	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
D3W51_RS06960	COG1286	toxin biosynthetic process
D3W51_RS06965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D3W51_RS06970	COG0163	prenyltransferase activity
D3W51_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS06985	COG4215	(ABC) transporter
D3W51_RS06990	COG4160	amino acid transport
D3W51_RS06995	COG4598	ABC transporter
D3W51_RS07000	COG5464	transposase or invertase
D3W51_RS07005	COG1090	epimerase
D3W51_RS07010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3W51_RS07015	COG0625	glutathione transferase activity
D3W51_RS07020	COG0625	glutathione transferase activity
D3W51_RS07025	COG0622	Phosphoesterase
D3W51_RS07030	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D3W51_RS07035	COG1288	antiporter activity
D3W51_RS07040	COG0280	phosphate acetyltransferase
D3W51_RS07040	COG0857	belongs to the CobB CobQ family
D3W51_RS07045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3W51_RS07060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3W51_RS07065	COG0471	metal ion transport
D3W51_RS07065	COG0490	domain, Protein
D3W51_RS07075	COG0436	Aminotransferase
D3W51_RS07080	COG0583	DNA-binding transcription factor activity
D3W51_RS07100	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
D3W51_RS07105	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D3W51_RS07110	COG1034	ATP synthesis coupled electron transport
D3W51_RS07125	COG0839	Belongs to the complex I subunit 6 family
D3W51_RS07135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3W51_RS07140	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3W51_RS07150	COG0457	Tetratricopeptide repeat
D3W51_RS07180	COG2234	aminopeptidase activity
D3W51_RS07185	COG2304	oxidoreductase activity
D3W51_RS07190	COG5160	protein modification by small protein removal
D3W51_RS07200	COG2153	protein acetylation
D3W51_RS07205	COG4575	ribosome binding
D3W51_RS07210	COG1169	isochorismate synthase
D3W51_RS07225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D3W51_RS07235	COG0318	PFAM AMP-dependent synthetase and ligase
D3W51_RS07300	COG1414	Transcriptional regulator
D3W51_RS07310	COG2271	Major facilitator Superfamily
D3W51_RS07325	COG5464	transposase or invertase
D3W51_RS07330	COG0247	lactate metabolic process
D3W51_RS07340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D3W51_RS07345	COG2271	Major facilitator Superfamily
D3W51_RS07350	COG0584	glycerophosphoryl diester phosphodiesterase
D3W51_RS07360	COG3642	lipopolysaccharide core region biosynthetic process
D3W51_RS07365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3W51_RS07370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3W51_RS07375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3W51_RS07380	COG3468	outer membrane autotransporter barrel domain protein
D3W51_RS07390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3W51_RS07395	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
D3W51_RS07400	COG3234	Protein of unknown function (DUF1175)
D3W51_RS07405	COG2373	Large extracellular alpha-helical protein
D3W51_RS07410	COG5445	Predicted secreted protein (DUF2300)
D3W51_RS07415	COG4676	Protein conserved in bacteria
D3W51_RS07420	COG0183	Belongs to the thiolase family
D3W51_RS07425	COG2031	fatty acid transporter
D3W51_RS07430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3W51_RS07435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3W51_RS07445	COG3852	Histidine kinase
D3W51_RS07450	COG0784	Response regulator, receiver
D3W51_RS07450	COG2205	protein histidine kinase activity
D3W51_RS07455	COG2197	response regulator
D3W51_RS07460	COG0642	Histidine kinase
D3W51_RS07460	COG2198	Histidine kinase
D3W51_RS07465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D3W51_RS07470	COG1477	protein flavinylation
D3W51_RS07475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3W51_RS07475	COG2169	Transcriptional regulator
D3W51_RS07480	COG3145	DNA-N1-methyladenine dioxygenase activity
D3W51_RS07485	COG4615	Cyclic peptide transporter
D3W51_RS07500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS07500	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3W51_RS07505	COG3062	negative regulation of establishment of protein localization
D3W51_RS07515	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS07520	COG0348	domain, Protein
D3W51_RS07525	COG3043	anaerobic respiration
D3W51_RS07530	COG3005	denitrification pathway
D3W51_RS07535	COG4133	protoheme IX ABC transporter activity
D3W51_RS07540	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3W51_RS07545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3W51_RS07550	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3W51_RS07560	COG1138	Cytochrome C-type biogenesis protein
D3W51_RS07565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3W51_RS07570	COG4235	cytochrome complex assembly
D3W51_RS07570	COG3088	subunit of a heme lyase
D3W51_RS07575	COG2197	response regulator
D3W51_RS07580	COG3468	outer membrane autotransporter barrel domain protein
D3W51_RS07610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3W51_RS07615	COG1061	Type III restriction enzyme res subunit
D3W51_RS07620	COG1002	Type II restriction enzyme, methylase subunits
D3W51_RS07675	COG0582	viral genome integration into host DNA
D3W51_RS07685	COG3083	sulfuric ester hydrolase activity
D3W51_RS07705	COG1061	Type III restriction enzyme res subunit
D3W51_RS07710	COG1187	pseudouridine synthase activity
D3W51_RS07715	COG2814	Major facilitator Superfamily
D3W51_RS07725	COG4172	Belongs to the ABC transporter superfamily
D3W51_RS07730	COG4239	(ABC) transporter, permease
D3W51_RS07735	COG4174	ABC transporter (Permease)
D3W51_RS07740	COG4166	transmembrane transport
D3W51_RS07745	COG2200	EAL domain
D3W51_RS07750	COG0791	NLP P60 protein
D3W51_RS07755	COG0671	phosphoesterase, PA-phosphatase related
D3W51_RS07760	COG0523	cobalamin synthesis protein
D3W51_RS07765	COG0246	Mannitol dehydrogenase
D3W51_RS07780	COG2814	Major facilitator Superfamily
D3W51_RS07785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS07785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS07790	COG1105	Belongs to the carbohydrate kinase PfkB family
D3W51_RS07795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS07795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D3W51_RS07795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS07800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS07805	COG2313	pseudouridylate synthase activity
D3W51_RS07810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3W51_RS07840	COG1522	sequence-specific DNA binding
D3W51_RS07840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS07850	COG2855	membrane
D3W51_RS07855	COG0583	DNA-binding transcription factor activity
D3W51_RS07860	COG0833	amino acid
D3W51_RS07865	COG4771	TonB-dependent receptor
D3W51_RS07880	COG2311	Membrane
D3W51_RS07885	COG1609	Transcriptional regulator
D3W51_RS07890	COG1879	ABC-type sugar transport system periplasmic component
D3W51_RS07895	COG1129	ABC transporter
D3W51_RS07900	COG4211	Belongs to the binding-protein-dependent transport system permease family
D3W51_RS07905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D3W51_RS07905	COG0167	dihydroorotate dehydrogenase activity
D3W51_RS07910	COG0493	'glutamate synthase
D3W51_RS07920	COG2949	membrane
D3W51_RS07930	COG1346	cytolysis
D3W51_RS07940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3W51_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS07960	COG0586	Pfam SNARE associated Golgi protein
D3W51_RS07970	COG1686	Belongs to the peptidase S11 family
D3W51_RS07975	COG0277	FAD linked oxidase domain protein
D3W51_RS07980	COG1472	Belongs to the glycosyl hydrolase 3 family
D3W51_RS07985	COG1732	Glycine betaine
D3W51_RS07990	COG1174	glycine betaine transport
D3W51_RS07995	COG1125	glycine betaine transport
D3W51_RS08000	COG1174	glycine betaine transport
D3W51_RS08010	COG0789	Transcriptional regulator
D3W51_RS08015	COG3275	phosphorelay sensor kinase activity
D3W51_RS08020	COG3279	Response regulator of the LytR AlgR family
D3W51_RS08025	COG4807	Protein conserved in bacteria
D3W51_RS08030	COG4808	Protein conserved in bacteria
D3W51_RS08035	COG4715	Zinc finger, swim domain protein
D3W51_RS08040	COG3552	Protein containing von Willebrand factor type A (VWA) domain
D3W51_RS08045	COG2425	protein containing a von Willebrand factor type A (vWA) domain
D3W51_RS08050	COG0714	Associated with various cellular activities
D3W51_RS08060	COG3831	ATPase activity
D3W51_RS08075	COG0489	protein tyrosine kinase activity
D3W51_RS08085	COG3539	Fimbrial protein
D3W51_RS08090	COG3121	Chaperone
D3W51_RS08095	COG3188	usher protein
D3W51_RS08100	COG3539	Fimbrial protein
D3W51_RS08105	COG5455	response to cobalt ion
D3W51_RS08125	COG0351	phosphomethylpyrimidine kinase
D3W51_RS08130	COG3757	hydrolase, family 25
D3W51_RS08135	COG2188	Transcriptional regulator
D3W51_RS08140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS08145	COG1397	ADP-ribosylglycohydrolase
D3W51_RS08150	COG2211	Major facilitator Superfamily
D3W51_RS08155	COG1830	Aldolase
D3W51_RS08170	COG1069	ribulokinase activity
D3W51_RS08195	COG1070	Carbohydrate kinase
D3W51_RS08205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3W51_RS08220	COG0826	peptidase U32
D3W51_RS08230	COG0745	RESPONSE REGULATOR receiver
D3W51_RS08235	COG2205	protein histidine kinase activity
D3W51_RS08270	COG4245	von Willebrand factor, type A
D3W51_RS08275	COG0631	protein serine/threonine phosphatase activity
D3W51_RS08280	COG3779	Protein conserved in bacteria
D3W51_RS08285	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
D3W51_RS08290	COG0443	Heat shock 70 kDa protein
D3W51_RS08295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D3W51_RS08300	COG5001	Diguanylate cyclase
D3W51_RS08300	COG5002	protein histidine kinase activity
D3W51_RS08300	COG3447	MASE1 domain protein
D3W51_RS08305	COG0572	uridine kinase
D3W51_RS08315	COG2982	Protein involved in outer membrane biogenesis
D3W51_RS08320	COG1253	flavin adenine dinucleotide binding
D3W51_RS08325	COG1596	polysaccharide export
D3W51_RS08330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3W51_RS08335	COG0489	protein tyrosine kinase activity
D3W51_RS08335	COG3206	protein involved in exopolysaccharide biosynthesis
D3W51_RS08340	COG0463	Glycosyl transferase, family 2
D3W51_RS08345	COG1045	serine acetyltransferase
D3W51_RS08350	COG0438	transferase activity, transferring glycosyl groups
D3W51_RS08360	COG1216	Glycosyl transferase, family 2
D3W51_RS08365	COG0110	maltose O-acetyltransferase activity
D3W51_RS08370	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D3W51_RS08375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3W51_RS08380	COG1051	belongs to the nudix hydrolase family
D3W51_RS08385	COG0297	glycogen (starch) synthase activity
D3W51_RS08390	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
D3W51_RS08390	COG0662	Cupin 2, conserved barrel domain protein
D3W51_RS08395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3W51_RS08400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D3W51_RS08405	COG2244	polysaccharide biosynthetic process
D3W51_RS08410	COG2327	Polysaccharide pyruvyl transferase
D3W51_RS08415	COG0438	transferase activity, transferring glycosyl groups
D3W51_RS08425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3W51_RS08430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3W51_RS08440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D3W51_RS08450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3W51_RS08480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3W51_RS08485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3W51_RS08490	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
D3W51_RS08515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D3W51_RS08520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D3W51_RS08520	COG0131	Imidazoleglycerol-phosphate dehydratase
D3W51_RS08530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3W51_RS08545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3W51_RS08550	COG0583	DNA-binding transcription factor activity
D3W51_RS08560	COG0531	amino acid
D3W51_RS08565	COG2391	methyltransferase activity
D3W51_RS08570	COG0425	Belongs to the sulfur carrier protein TusA family
D3W51_RS08575	COG2925	Exonuclease
D3W51_RS08580	COG1686	Belongs to the peptidase S11 family
D3W51_RS08590	COG1289	transmembrane transporter activity
D3W51_RS08625	COG1278	Cold shock
D3W51_RS08630	COG1278	Cold shock
D3W51_RS08650	COG0348	domain, Protein
D3W51_RS08655	COG2205	protein histidine kinase activity
D3W51_RS08655	COG0784	Response regulator, receiver
D3W51_RS08655	COG2198	Histidine kinase
D3W51_RS08660	COG1879	ABC-type sugar transport system periplasmic component
D3W51_RS08665	COG0745	RESPONSE REGULATOR receiver
D3W51_RS08670	COG3005	denitrification pathway
D3W51_RS08675	COG0243	molybdopterin cofactor binding
D3W51_RS08680	COG3381	protein complex oligomerization
D3W51_RS08720	COG3729	General stress protein
D3W51_RS08765	COG1309	transcriptional regulator
D3W51_RS08770	COG0506	proline dehydrogenase activity
D3W51_RS08770	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D3W51_RS08770	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D3W51_RS08780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3W51_RS08790	COG2822	iron ion transport
D3W51_RS08795	COG2837	iron assimilation
D3W51_RS08800	COG1702	phosphate starvation-inducible protein PhoH
D3W51_RS08805	COG3658	cytochrome
D3W51_RS08825	COG1649	PFAM Uncharacterised BCR, COG1649
D3W51_RS08825	COG0726	polysaccharide deacetylase
D3W51_RS08830	COG0457	Tetratricopeptide repeat
D3W51_RS08835	COG3706	GGDEF domain
D3W51_RS08870	COG3381	protein complex oligomerization
D3W51_RS08880	COG1462	curli production assembly transport component CsgG
D3W51_RS08895	COG2197	response regulator
D3W51_RS08920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D3W51_RS08925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3W51_RS08940	COG2943	transferase activity, transferring hexosyl groups
D3W51_RS08945	COG5645	(Lipo)protein
D3W51_RS08960	COG1560	Kdo2-lipid A biosynthetic process
D3W51_RS08970	COG2353	YceI-like domain
D3W51_RS08975	COG3038	cytochrome b561
D3W51_RS09010	COG2999	glutathione oxidoreductase activity
D3W51_RS09020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3W51_RS09030	COG0673	inositol 2-dehydrogenase activity
D3W51_RS09035	COG0728	peptidoglycan biosynthetic process
D3W51_RS09040	COG3418	PFAM FlgN family protein
D3W51_RS09045	COG2747	anti-sigma28 factor FlgM
D3W51_RS09050	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
D3W51_RS09055	COG1815	bacterial-type flagellum-dependent cell motility
D3W51_RS09060	COG1558	bacterial-type flagellum-dependent cell motility
D3W51_RS09065	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D3W51_RS09070	COG1749	Flagellar hook protein flgE
D3W51_RS09075	COG4787	bacterial-type flagellum-dependent cell motility
D3W51_RS09080	COG4786	Flagellar basal body rod
D3W51_RS09095	COG1705	Flagellar rod assembly protein muramidase FlgJ
D3W51_RS09095	COG3951	Flagellar rod assembly protein muramidase FlgJ
D3W51_RS09100	COG1256	bacterial-type flagellum assembly
D3W51_RS09105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3W51_RS09110	COG1530	ribonuclease E activity
D3W51_RS09120	COG0564	pseudouridine synthase activity
D3W51_RS09125	COG0424	maF-like protein
D3W51_RS09130	COG1399	metal-binding, possibly nucleic acid-binding protein
D3W51_RS09150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3W51_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS09165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3W51_RS09170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3W51_RS09175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3W51_RS09185	COG0470	DNA polymerase III
D3W51_RS09190	COG0084	hydrolase, TatD family'
D3W51_RS09195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS09195	COG1263	PTS System
D3W51_RS09200	COG4773	Receptor
D3W51_RS09205	COG0537	adenosine 5'-monophosphoramidase activity
D3W51_RS09210	COG5633	Lipoprotein
D3W51_RS09215	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
D3W51_RS09235	COG1252	NADH dehydrogenase
D3W51_RS09240	COG3134	Outer membrane lipoprotein
D3W51_RS09245	COG1309	transcriptional regulator
D3W51_RS09255	COG1388	LysM domain
D3W51_RS09255	COG1376	ErfK ybiS ycfS ynhG family protein
D3W51_RS09260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3W51_RS09265	COG4763	Acyl-transferase
D3W51_RS09270	COG4591	ABC-type transport system involved in lipoprotein release permease component
D3W51_RS09275	COG1136	(ABC) transporter
D3W51_RS09280	COG4591	ABC-type transport system involved in lipoprotein release permease component
D3W51_RS09290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D3W51_RS09295	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D3W51_RS09305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D3W51_RS09310	COG1177	transmembrane transport
D3W51_RS09320	COG3842	ATPase activity
D3W51_RS09330	COG2850	peptidyl-arginine hydroxylation
D3W51_RS09335	COG2205	protein histidine kinase activity
D3W51_RS09340	COG0745	RESPONSE REGULATOR receiver
D3W51_RS09345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3W51_RS09365	COG1187	pseudouridine synthase activity
D3W51_RS09370	COG0538	isocitrate dehydrogenase activity
D3W51_RS09385	COG5562	phage envelope protein
D3W51_RS09460	COG2894	cell division
D3W51_RS09485	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3W51_RS09500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D3W51_RS09505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3W51_RS09510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D3W51_RS09525	COG2719	SpoVR family
D3W51_RS09535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3W51_RS09545	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3W51_RS09555	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D3W51_RS09560	COG2261	transglycosylase associated protein
D3W51_RS09575	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
D3W51_RS09575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS09575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3W51_RS09580	COG1461	Dihydroxyacetone kinase
D3W51_RS09585	COG2376	Dihydroxyacetone kinase
D3W51_RS09590	COG3284	Transcriptional regulator
D3W51_RS09600	COG3039	Transposase
D3W51_RS09605	COG3468	outer membrane autotransporter barrel domain protein
D3W51_RS09610	COG0012	GTP binding
D3W51_RS09625	COG0659	secondary active sulfate transmembrane transporter activity
D3W51_RS09630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3W51_RS09655	COG2890	protein-(glutamine-N5) methyltransferase activity
D3W51_RS09660	COG3094	Invasion gene expression up-regulator, SirB
D3W51_RS09665	COG2912	Transglutaminase-like superfamily
D3W51_RS09695	COG0387	Pfam Sodium calcium exchanger
D3W51_RS09700	COG4572	Cation transport regulator
D3W51_RS09705	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D3W51_RS09710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D3W51_RS09715	COG4932	domain protein
D3W51_RS09720	COG2197	response regulator
D3W51_RS09725	COG3850	Histidine kinase
D3W51_RS09730	COG2223	nitrite transmembrane transporter activity
D3W51_RS09735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D3W51_RS09740	COG1140	nitrate reductase beta subunit
D3W51_RS09745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D3W51_RS09750	COG2181	nitrate reductase activity
D3W51_RS09780	COG0788	formyltetrahydrofolate deformylase activity
D3W51_RS09790	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3W51_RS09795	COG0745	RESPONSE REGULATOR receiver
D3W51_RS09800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3W51_RS09810	COG1435	thymidine kinase activity
D3W51_RS09820	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS09820	COG1454	alcohol dehydrogenase
D3W51_RS09825	COG2095	MarC family integral membrane protein
D3W51_RS09830	COG4166	transmembrane transport
D3W51_RS09835	COG0601	transmembrane transport
D3W51_RS09840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3W51_RS09845	COG0444	Belongs to the ABC transporter superfamily
D3W51_RS09850	COG4608	Belongs to the ABC transporter superfamily
D3W51_RS09870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3W51_RS09875	COG2350	Protein conserved in bacteria
D3W51_RS09880	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
D3W51_RS09885	COG1607	acyl-coa hydrolase
D3W51_RS09905	COG3047	cAMP biosynthetic process
D3W51_RS09910	COG3685	Protein conserved in bacteria
D3W51_RS09915	COG3685	Protein conserved in bacteria
D3W51_RS09920	COG3729	General stress protein
D3W51_RS09925	COG3039	Transposase
D3W51_RS09930	COG0159	tryptophan synthase activity
D3W51_RS09940	COG0134	indole-3-glycerol-phosphate synthase activity
D3W51_RS09940	COG0135	phosphoribosylanthranilate isomerase activity
D3W51_RS09945	COG0512	Glutamine amidotransferase of anthranilate synthase
D3W51_RS09945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3W51_RS09950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3W51_RS09960	COG0613	PHP domain protein
D3W51_RS09965	COG0009	L-threonylcarbamoyladenylate synthase
D3W51_RS09970	COG4907	membrane protein (DUF2207)
D3W51_RS09975	COG1187	pseudouridine synthase activity
D3W51_RS09980	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
D3W51_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS09990	COG0616	signal peptide processing
D3W51_RS10000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3W51_RS10005	COG0583	DNA-binding transcription factor activity
D3W51_RS10025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3W51_RS10035	COG0671	phosphoesterase, PA-phosphatase related
D3W51_RS10040	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
D3W51_RS10045	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D3W51_RS10055	COG0023	Translation Initiation Factor
D3W51_RS10065	COG1349	DNA-binding transcription factor activity
D3W51_RS10075	COG5001	Diguanylate cyclase
D3W51_RS10090	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3W51_RS10090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3W51_RS10095	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D3W51_RS10100	COG2852	Protein conserved in bacteria
D3W51_RS10105	COG4172	Belongs to the ABC transporter superfamily
D3W51_RS10110	COG4172	Belongs to the ABC transporter superfamily
D3W51_RS10115	COG4171	peptide transport system, permease
D3W51_RS10120	COG4168	peptide transport system, permease
D3W51_RS10125	COG4166	transmembrane transport
D3W51_RS10135	COG0531	amino acid
D3W51_RS10145	COG0174	glutamine synthetase
D3W51_RS10150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D3W51_RS10155	COG1917	Cupin 2, conserved barrel domain protein
D3W51_RS10155	COG1396	sequence-specific DNA binding
D3W51_RS10160	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS10165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3W51_RS10170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3W51_RS10175	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3W51_RS10180	COG1842	Phage shock protein A
D3W51_RS10190	COG1983	PspC domain protein
D3W51_RS10200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3W51_RS10205	COG0366	Alpha amylase catalytic
D3W51_RS10210	COG1653	transport
D3W51_RS10215	COG1175	transmembrane transport
D3W51_RS10220	COG0395	ABC-type sugar transport system, permease component
D3W51_RS10225	COG1063	alcohol dehydrogenase
D3W51_RS10230	COG1082	Xylose isomerase domain protein TIM barrel
D3W51_RS10235	COG0673	inositol 2-dehydrogenase activity
D3W51_RS10240	COG1554	hydrolase, family 65, central catalytic
D3W51_RS10245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3W51_RS10250	COG3842	ATPase activity
D3W51_RS10260	COG1609	Transcriptional regulator
D3W51_RS10265	COG3106	COG3106 Predicted ATPase
D3W51_RS10275	COG3283	Transcriptional regulator of aromatic amino acids metabolism
D3W51_RS10280	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D3W51_RS10285	COG4948	Mandelate Racemase Muconate Lactonizing
D3W51_RS10290	COG2866	Carboxypeptidase
D3W51_RS10305	COG1073	alpha beta
D3W51_RS10310	COG0583	DNA-binding transcription factor activity
D3W51_RS10315	COG4166	transmembrane transport
D3W51_RS10320	COG0668	transmembrane transport
D3W51_RS10325	COG3182	Iron-regulated membrane protein
D3W51_RS10330	COG0589	response to stress
D3W51_RS10335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3W51_RS10340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3W51_RS10345	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D3W51_RS10350	COG1473	amidohydrolase
D3W51_RS10355	COG1473	amidohydrolase
D3W51_RS10360	COG0583	DNA-binding transcription factor activity
D3W51_RS10365	COG2840	Smr protein MutS2
D3W51_RS10370	COG3706	GGDEF domain
D3W51_RS10380	COG0513	Belongs to the DEAD box helicase family
D3W51_RS10390	COG0582	viral genome integration into host DNA
D3W51_RS10410	COG3723	Recombinational DNA repair protein, rece pathway
D3W51_RS10415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3W51_RS10475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3W51_RS10495	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D3W51_RS10500	COG2814	Major facilitator Superfamily
D3W51_RS10535	COG3064	Membrane
D3W51_RS10550	COG3772	lysozyme
D3W51_RS10560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3W51_RS10565	COG1475	DNA binding
D3W51_RS10645	COG1196	nuclear chromosome segregation
D3W51_RS10650	COG3039	Transposase
D3W51_RS10655	COG0589	response to stress
D3W51_RS10660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D3W51_RS10665	COG0674	pyruvate-flavodoxin oxidoreductase activity
D3W51_RS10665	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D3W51_RS10665	COG1013	pyruvate-flavodoxin oxidoreductase activity
D3W51_RS10665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3W51_RS10670	COG3042	response to heat
D3W51_RS10675	COG3187	Heat shock protein
D3W51_RS10680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3W51_RS10685	COG2911	Protein conserved in bacteria
D3W51_RS10695	COG3784	Protein of unknown function (DUF1318)
D3W51_RS10700	COG2207	Transcriptional regulator
D3W51_RS10705	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS10710	COG3733	amine oxidase
D3W51_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS10715	COG2030	dehydratase
D3W51_RS10720	COG3396	Phenylacetate-CoA oxygenase
D3W51_RS10725	COG3460	Phenylacetate-CoA oxygenase
D3W51_RS10730	COG3396	Phenylacetate-CoA oxygenase
D3W51_RS10735	COG2151	metal-sulfur cluster biosynthetic enzyme
D3W51_RS10740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3W51_RS10745	COG1024	Enoyl-CoA hydratase
D3W51_RS10750	COG1024	Enoyl-CoA hydratase
D3W51_RS10755	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3W51_RS10760	COG2050	protein possibly involved in aromatic compounds catabolism
D3W51_RS10765	COG0183	Belongs to the thiolase family
D3W51_RS10770	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
D3W51_RS10775	COG3327	negative regulation of DNA-templated transcription, initiation
D3W51_RS10780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3W51_RS10815	COG0667	Aldo Keto reductase
D3W51_RS10825	COG3039	Transposase
D3W51_RS10835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3W51_RS10840	COG4589	Belongs to the CDS family
D3W51_RS10845	COG2267	carboxylic ester hydrolase activity
D3W51_RS10850	COG2453	phosphatase
D3W51_RS10850	COG0671	phosphoesterase, PA-phosphatase related
D3W51_RS10860	COG1643	Atp-dependent helicase
D3W51_RS10865	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D3W51_RS10870	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS10880	COG3038	cytochrome b561
D3W51_RS10905	COG0840	transmembrane signaling receptor activity
D3W51_RS10910	COG0583	DNA-binding transcription factor activity
D3W51_RS10915	COG5383	Protein conserved in bacteria
D3W51_RS10925	COG2841	Protein conserved in bacteria
D3W51_RS10930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3W51_RS10935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3W51_RS10940	COG1275	C4-dicarboxylate transporter malic acid transport protein
D3W51_RS10945	COG0500	methyltransferase
D3W51_RS10960	COG0675	Transposase, IS605 OrfB family
D3W51_RS10965	COG3135	benzoate transporter
D3W51_RS10970	COG1396	sequence-specific DNA binding
D3W51_RS10975	COG0826	peptidase U32
D3W51_RS10985	COG1724	mRNA binding
D3W51_RS10990	COG1598	PFAM Uncharacterised protein family UPF0150
D3W51_RS10995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3W51_RS11000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D3W51_RS11005	COG3842	ATPase activity
D3W51_RS11010	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3W51_RS11015	COG1177	transmembrane transport
D3W51_RS11040	COG3238	Protein conserved in bacteria
D3W51_RS11045	COG1247	-acetyltransferase
D3W51_RS11050	COG2130	NADP-dependent
D3W51_RS11055	COG1802	Transcriptional regulator
D3W51_RS11060	COG4772	TonB-dependent receptor
D3W51_RS11065	COG3391	amine dehydrogenase activity
D3W51_RS11070	COG1113	amino acid transport
D3W51_RS11075	COG0625	glutathione transferase activity
D3W51_RS11090	COG3209	COG3209 Rhs family protein
D3W51_RS11115	COG5433	transposase activity
D3W51_RS11125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3W51_RS11130	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D3W51_RS11135	COG0384	phenazine biosynthesis protein PhzF
D3W51_RS11140	COG2181	nitrate reductase activity
D3W51_RS11145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D3W51_RS11150	COG1140	nitrate reductase beta subunit
D3W51_RS11155	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D3W51_RS11160	COG2223	nitrite transmembrane transporter activity
D3W51_RS11165	COG3039	Transposase
D3W51_RS11170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D3W51_RS11175	COG0697	spore germination
D3W51_RS11180	COG0243	molybdopterin cofactor binding
D3W51_RS11180	COG3383	formate dehydrogenase (NAD+) activity
D3W51_RS11185	COG0243	molybdopterin cofactor binding
D3W51_RS11185	COG3383	formate dehydrogenase (NAD+) activity
D3W51_RS11190	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS11195	COG2864	formate dehydrogenase
D3W51_RS11200	COG3093	addiction module antidote protein HigA
D3W51_RS11205	COG1064	alcohol dehydrogenase
D3W51_RS11225	COG1764	response to oxidative stress
D3W51_RS11230	COG4608	Belongs to the ABC transporter superfamily
D3W51_RS11235	COG0444	Belongs to the ABC transporter superfamily
D3W51_RS11240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3W51_RS11245	COG0601	transmembrane transport
D3W51_RS11250	COG0747	negative chemotaxis
D3W51_RS11255	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
D3W51_RS11260	COG2202	Pas domain
D3W51_RS11260	COG2200	EAL domain
D3W51_RS11260	COG2199	diguanylate cyclase activity
D3W51_RS11265	COG3706	GGDEF domain
D3W51_RS11270	COG1649	PFAM Uncharacterised BCR, COG1649
D3W51_RS11275	COG0531	amino acid
D3W51_RS11280	COG0076	glutamate decarboxylase activity
D3W51_RS11285	COG0612	Peptidase, M16
D3W51_RS11295	COG4771	TonB-dependent receptor
D3W51_RS11300	COG4178	(ABC) transporter
D3W51_RS11310	COG0641	radical SAM
D3W51_RS11315	COG3119	arylsulfatase activity
D3W51_RS11320	COG2207	Transcriptional regulator
D3W51_RS11330	COG0243	molybdopterin cofactor binding
D3W51_RS11335	COG3539	Fimbrial protein
D3W51_RS11340	COG3539	Fimbrial protein
D3W51_RS11345	COG3539	Fimbrial protein
D3W51_RS11420	COG3550	peptidyl-serine autophosphorylation
D3W51_RS11425	COG1396	sequence-specific DNA binding
D3W51_RS11485	COG3781	membrane
D3W51_RS11495	COG2199	diguanylate cyclase activity
D3W51_RS11505	COG2066	Belongs to the glutaminase family
D3W51_RS11510	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS11515	COG0583	DNA-binding transcription factor activity
D3W51_RS11535	COG1846	Transcriptional regulator
D3W51_RS11540	COG4977	sequence-specific DNA binding
D3W51_RS11550	COG0697	spore germination
D3W51_RS11555	COG2814	Major facilitator Superfamily
D3W51_RS11565	COG3706	GGDEF domain
D3W51_RS11570	COG3111	PFAM Bacterial OB fold (BOF) protein
D3W51_RS11575	COG1546	Belongs to the CinA family
D3W51_RS11580	COG0339	signal peptide processing
D3W51_RS11585	COG4221	oxidoreductase activity
D3W51_RS11590	COG1802	Transcriptional regulator
D3W51_RS11605	COG0477	Major facilitator Superfamily
D3W51_RS11620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3W51_RS11625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D3W51_RS11705	COG0740	serine-type endopeptidase activity
D3W51_RS11775	COG3772	lysozyme
D3W51_RS11790	COG1278	Cold shock
D3W51_RS11800	COG0484	heat shock protein binding
D3W51_RS11805	COG1403	HNH endonuclease
D3W51_RS11850	COG1846	Transcriptional regulator
D3W51_RS11865	COG1396	sequence-specific DNA binding
D3W51_RS11885	COG3436	PFAM IS66 Orf2 family protein
D3W51_RS11890	COG0582	viral genome integration into host DNA
D3W51_RS11900	COG1063	alcohol dehydrogenase
D3W51_RS11905	COG4948	Mandelate Racemase Muconate Lactonizing
D3W51_RS11920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3W51_RS11935	COG0243	molybdopterin cofactor binding
D3W51_RS11940	COG0243	molybdopterin cofactor binding
D3W51_RS11945	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS11950	COG3302	dmso reductase anchor subunit
D3W51_RS11955	COG3381	protein complex oligomerization
D3W51_RS11965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D3W51_RS11970	COG1940	carbohydrate kinase activity
D3W51_RS11975	COG0583	DNA-binding transcription factor activity
D3W51_RS11980	COG2814	Major facilitator Superfamily
D3W51_RS11995	COG3591	Belongs to the peptidase S1B family
D3W51_RS12015	COG0628	permease
D3W51_RS12020	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D3W51_RS12025	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D3W51_RS12035	COG0531	amino acid
D3W51_RS12045	COG3136	membrane protein required for alginate biosynthesis
D3W51_RS12050	COG0745	RESPONSE REGULATOR receiver
D3W51_RS12055	COG2205	protein histidine kinase activity
D3W51_RS12065	COG0114	fumarate hydratase activity
D3W51_RS12070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D3W51_RS12070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D3W51_RS12075	COG1482	cell wall glycoprotein biosynthetic process
D3W51_RS12080	COG5339	Protein conserved in bacteria
D3W51_RS12105	COG3250	beta-galactosidase activity
D3W51_RS12110	COG1309	transcriptional regulator
D3W51_RS12115	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS12120	COG1609	Transcriptional regulator
D3W51_RS12125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS12125	COG1263	PTS System
D3W51_RS12130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D3W51_RS12140	COG0673	inositol 2-dehydrogenase activity
D3W51_RS12180	COG4659	FMN binding
D3W51_RS12190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3W51_RS12195	COG3104	oligopeptide transport
D3W51_RS12200	COG0625	glutathione transferase activity
D3W51_RS12205	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D3W51_RS12220	COG3895	Periplasmic Protein
D3W51_RS12230	COG3133	Outer membrane lipoprotein
D3W51_RS12245	COG1566	PFAM secretion protein HlyD family protein
D3W51_RS12250	COG1289	transmembrane transporter activity
D3W51_RS12255	COG2032	superoxide dismutase activity
D3W51_RS12260	COG4989	oxidoreductase activity
D3W51_RS12265	COG3313	Fe-S protein
D3W51_RS12270	COG1309	transcriptional regulator
D3W51_RS12275	COG1902	pentaerythritol trinitrate reductase activity
D3W51_RS12280	COG0346	lactoylglutathione lyase activity
D3W51_RS12285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3W51_RS12290	COG1201	RNA secondary structure unwinding
D3W51_RS12295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D3W51_RS12300	COG0791	NLP P60 protein
D3W51_RS12305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3W51_RS12310	COG2814	Major facilitator Superfamily
D3W51_RS12325	COG0583	DNA-binding transcription factor activity
D3W51_RS12330	COG2814	Major facilitator Superfamily
D3W51_RS12335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D3W51_RS12340	COG0307	riboflavin synthase, alpha
D3W51_RS12350	COG3468	outer membrane autotransporter barrel domain protein
D3W51_RS12370	COG4529	Protein conserved in bacteria
D3W51_RS12380	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
D3W51_RS12385	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS12395	COG2414	aldehyde ferredoxin oxidoreductase
D3W51_RS12400	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS12410	COG0469	pyruvate kinase activity
D3W51_RS12415	COG4238	major outer membrane lipoprotein
D3W51_RS12420	COG1376	ErfK ybiS ycfS ynhG family protein
D3W51_RS12435	COG0719	Fe-S assembly protein
D3W51_RS12440	COG0396	ATPase activity
D3W51_RS12445	COG0719	Fe-S assembly protein
D3W51_RS12450	COG0316	Belongs to the HesB IscA family
D3W51_RS12460	COG2050	protein possibly involved in aromatic compounds catabolism
D3W51_RS12465	COG0277	FAD linked oxidase domain protein
D3W51_RS12465	COG0247	lactate metabolic process
D3W51_RS12470	COG0628	permease
D3W51_RS12485	COG0738	Major facilitator superfamily
D3W51_RS12490	COG2271	Major facilitator Superfamily
D3W51_RS12505	COG4670	ketone body catabolic process
D3W51_RS12510	COG1960	acyl-CoA dehydrogenase activity
D3W51_RS12515	COG1917	Cupin 2, conserved barrel domain protein
D3W51_RS12515	COG2207	Transcriptional regulator
D3W51_RS12520	COG2086	electron transfer activity
D3W51_RS12525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D3W51_RS12530	COG0644	oxidoreductase
D3W51_RS12535	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D3W51_RS12540	COG0318	PFAM AMP-dependent synthetase and ligase
D3W51_RS12545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3W51_RS12545	COG0574	Belongs to the PEP-utilizing enzyme family
D3W51_RS12555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D3W51_RS12560	COG4256	Hemin uptake protein
D3W51_RS12570	COG2200	EAL domain
D3W51_RS12575	COG0791	NLP P60 protein
D3W51_RS12585	COG0386	Belongs to the glutathione peroxidase family
D3W51_RS12600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3W51_RS12600	COG0072	phenylalanine-tRNA ligase activity
D3W51_RS12645	COG3137	Salt-induced outer membrane protein
D3W51_RS12650	COG1105	Belongs to the carbohydrate kinase PfkB family
D3W51_RS12660	COG3001	Fructosamine kinase
D3W51_RS12670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3W51_RS12675	COG1988	membrane-bound metal-dependent
D3W51_RS12680	COG1823	symporter activity
D3W51_RS12695	COG0753	catalase activity
D3W51_RS12705	COG1486	melibiose metabolic process
D3W51_RS12710	COG2169	Transcriptional regulator
D3W51_RS12710	COG1917	Cupin 2, conserved barrel domain protein
D3W51_RS12715	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3W51_RS12720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3W51_RS12725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3W51_RS12735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3W51_RS12745	COG0322	excinuclease ABC activity
D3W51_RS12755	COG3678	ATP-independent chaperone mediated protein folding
D3W51_RS12785	COG0708	Exodeoxyribonuclease III
D3W51_RS12790	COG0398	Pfam SNARE associated Golgi protein
D3W51_RS12800	COG0398	Pfam SNARE associated Golgi protein
D3W51_RS12805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3W51_RS12810	COG4134	Bacterial extracellular solute-binding protein
D3W51_RS12815	COG4135	transport system, permease component
D3W51_RS12820	COG4136	ATPase activity
D3W51_RS12825	COG2897	thiosulfate sulfurtransferase activity
D3W51_RS12830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3W51_RS12835	COG0494	nUDIX hydrolase
D3W51_RS12845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3W51_RS12855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3W51_RS12865	COG0778	Nitroreductase
D3W51_RS12870	COG0616	signal peptide processing
D3W51_RS12875	COG0252	asparaginase activity
D3W51_RS12880	COG1335	isochorismatase
D3W51_RS12885	COG2814	Major facilitator Superfamily
D3W51_RS12890	COG1349	DNA-binding transcription factor activity
D3W51_RS12895	COG0667	Aldo Keto reductase
D3W51_RS12900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS12905	COG0191	fructose-bisphosphate aldolase activity
D3W51_RS12910	COG1063	alcohol dehydrogenase
D3W51_RS12915	COG2271	Major facilitator Superfamily
D3W51_RS12920	COG1063	alcohol dehydrogenase
D3W51_RS12925	COG3139	Protein of unknown function (DUF1315)
D3W51_RS12935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3W51_RS12940	COG0676	glucose-6-phosphate 1-epimerase activity
D3W51_RS12945	COG0656	L-ascorbic acid biosynthetic process
D3W51_RS12950	COG3713	MltA-interacting MipA family protein
D3W51_RS12955	COG2766	serine protein kinase
D3W51_RS12965	COG2199	diguanylate cyclase activity
D3W51_RS12970	COG2199	diguanylate cyclase activity
D3W51_RS12975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3W51_RS12990	COG2207	Transcriptional regulator
D3W51_RS12995	COG2807	transmembrane transport
D3W51_RS13000	COG3189	MarR family transcriptional regulator
D3W51_RS13005	COG3042	response to heat
D3W51_RS13010	COG2203	Gaf domain
D3W51_RS13010	COG2199	diguanylate cyclase activity
D3W51_RS13025	COG2261	transglycosylase associated protein
D3W51_RS13035	COG3615	Tellurite resistance protein tehB
D3W51_RS13045	COG0583	DNA-binding transcription factor activity
D3W51_RS13050	COG0473	3-isopropylmalate dehydrogenase activity
D3W51_RS13055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3W51_RS13060	COG4638	Rieske (2fe-2S)
D3W51_RS13065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3W51_RS13070	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D3W51_RS13075	COG0318	PFAM AMP-dependent synthetase and ligase
D3W51_RS13080	COG3065	identical protein binding
D3W51_RS13085	COG1214	PFAM Peptidase M22, glycoprotease
D3W51_RS13090	COG1199	ATP-dependent helicase activity
D3W51_RS13095	COG0251	oxidation-reduction process
D3W51_RS13110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3W51_RS13120	COG1760	l-serine dehydratase
D3W51_RS13125	COG2200	EAL domain
D3W51_RS13130	COG1253	flavin adenine dinucleotide binding
D3W51_RS13135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS13135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS13140	COG3715	PTS system
D3W51_RS13145	COG3716	PTS system mannose fructose sorbose family IID component
D3W51_RS13160	COG2226	methyltransferase
D3W51_RS13190	COG1414	Transcriptional regulator
D3W51_RS13195	COG2814	Major facilitator Superfamily
D3W51_RS13205	COG0793	Belongs to the peptidase S41A family
D3W51_RS13215	COG1956	GAF domain-containing protein
D3W51_RS13220	COG2995	paraquat-inducible protein a
D3W51_RS13225	COG3008	intermembrane lipid transfer
D3W51_RS13245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D3W51_RS13255	COG1276	copper resistance
D3W51_RS13260	COG2372	response to copper ion
D3W51_RS13270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3W51_RS13275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3W51_RS13280	COG1770	oligopeptidase
D3W51_RS13285	COG2979	Protein of unknown function (DUF533)
D3W51_RS13295	COG3141	response to X-ray
D3W51_RS13305	COG0800	Aldolase
D3W51_RS13310	COG0129	dihydroxy-acid dehydratase activity
D3W51_RS13315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D3W51_RS13320	COG1737	Transcriptional regulator
D3W51_RS13325	COG0469	pyruvate kinase activity
D3W51_RS13330	COG1560	Kdo2-lipid A biosynthetic process
D3W51_RS13335	COG0739	heme binding
D3W51_RS13340	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D3W51_RS13350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3W51_RS13380	COG0217	transcriptional regulatory protein
D3W51_RS13385	COG0494	nUDIX hydrolase
D3W51_RS13395	COG1335	isochorismatase
D3W51_RS13400	COG1801	Protein of unknown function DUF72
D3W51_RS13405	COG3788	relative of glutathione S-transferase, MAPEG superfamily
D3W51_RS13420	COG0243	molybdopterin cofactor binding
D3W51_RS13425	COG3005	denitrification pathway
D3W51_RS13435	COG3102	Protein conserved in bacteria
D3W51_RS13445	COG3755	Protein conserved in bacteria
D3W51_RS13455	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3W51_RS13460	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3W51_RS13465	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D3W51_RS13470	COG0745	RESPONSE REGULATOR receiver
D3W51_RS13475	COG2201	protein-glutamate methylesterase activity
D3W51_RS13480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D3W51_RS13485	COG0840	transmembrane signaling receptor activity
D3W51_RS13490	COG0840	transmembrane signaling receptor activity
D3W51_RS13495	COG0835	chemotaxis
D3W51_RS13500	COG2198	Histidine kinase
D3W51_RS13500	COG0643	Histidine kinase
D3W51_RS13505	COG1360	Flagellar Motor Protein
D3W51_RS13510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3W51_RS13525	COG0589	response to stress
D3W51_RS13535	COG1877	trehalose-phosphatase activity
D3W51_RS13540	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3W51_RS13545	COG1129	ABC transporter
D3W51_RS13550	COG1879	ABC-type sugar transport system periplasmic component
D3W51_RS13555	COG1528	Iron-storage protein
D3W51_RS13575	COG1528	Iron-storage protein
D3W51_RS13585	COG0814	amino acid
D3W51_RS13590	COG3012	SEC-C Motif Domain Protein
D3W51_RS13590	COG3318	Belongs to the UPF0149 family
D3W51_RS13630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D3W51_RS13635	COG3318	Belongs to the UPF0149 family
D3W51_RS13635	COG3012	SEC-C Motif Domain Protein
D3W51_RS13750	COG2197	response regulator
D3W51_RS13770	COG2197	response regulator
D3W51_RS13775	COG1126	abc transporter atp-binding protein
D3W51_RS13780	COG0765	amino acid transport
D3W51_RS13790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS13800	COG1191	sigma factor activity
D3W51_RS13815	COG1516	flagellar protein fliS
D3W51_RS13825	COG0366	Alpha amylase catalytic
D3W51_RS13835	COG2391	methyltransferase activity
D3W51_RS13840	COG0425	Belongs to the sulfur carrier protein TusA family
D3W51_RS13845	COG2135	peptidase activity
D3W51_RS13850	COG0675	Transposase, IS605 OrfB family
D3W51_RS13875	COG1881	PFAM PEBP family protein
D3W51_RS13880	COG2076	Multidrug Resistance protein
D3W51_RS13895	COG1766	The M ring may be actively involved in energy transduction
D3W51_RS13900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3W51_RS13905	COG1317	bacterial-type flagellum organization
D3W51_RS13910	COG1157	protein secretion by the type III secretion system
D3W51_RS13915	COG2882	bacterial-type flagellum organization
D3W51_RS13920	COG3144	bacterial-type flagellum assembly
D3W51_RS13925	COG1580	Controls the rotational direction of flagella during chemotaxis
D3W51_RS13930	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3W51_RS13935	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3W51_RS13940	COG3190	flagellar
D3W51_RS13945	COG1338	Plays a role in the flagellum-specific transport system
D3W51_RS13950	COG1987	bacterial-type flagellum assembly
D3W51_RS13955	COG1684	flagellar biosynthetic protein fliR
D3W51_RS13960	COG2197	response regulator
D3W51_RS13980	COG3706	GGDEF domain
D3W51_RS13985	COG5475	Uncharacterized small protein (DUF2158)
D3W51_RS13990	COG2354	Protein conserved in bacteria
D3W51_RS13995	COG0697	spore germination
D3W51_RS14000	COG3727	T/G mismatch-specific endonuclease activity
D3W51_RS14005	COG0270	DNA (cytosine-5-)-methyltransferase activity
D3W51_RS14010	COG1418	mRNA catabolic process
D3W51_RS14020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D3W51_RS14035	COG2205	protein histidine kinase activity
D3W51_RS14040	COG0745	RESPONSE REGULATOR receiver
D3W51_RS14045	COG2351	hydroxyisourate hydrolase activity
D3W51_RS14060	COG3443	Belongs to the bacterial solute-binding protein 9 family
D3W51_RS14065	COG3038	cytochrome b561
D3W51_RS14085	COG1388	LysM domain
D3W51_RS14085	COG1470	cell adhesion involved in biofilm formation
D3W51_RS14095	COG0477	Major facilitator Superfamily
D3W51_RS14100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D3W51_RS14105	COG0217	transcriptional regulatory protein
D3W51_RS14115	COG0534	Mate efflux family protein
D3W51_RS14125	COG0583	DNA-binding transcription factor activity
D3W51_RS14130	COG0583	DNA-binding transcription factor activity
D3W51_RS14140	COG1376	ErfK ybiS ycfS ynhG family protein
D3W51_RS14155	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
D3W51_RS14205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3W51_RS14210	COG1596	polysaccharide export
D3W51_RS14215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3W51_RS14220	COG0489	protein tyrosine kinase activity
D3W51_RS14220	COG3206	protein involved in exopolysaccharide biosynthesis
D3W51_RS14235	COG1294	oxidase, subunit
D3W51_RS14240	COG1271	oxidase subunit
D3W51_RS14245	COG1773	rubredoxin
D3W51_RS14250	COG1999	signal sequence binding
D3W51_RS14255	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D3W51_RS14260	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
D3W51_RS14265	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
D3W51_RS14270	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
D3W51_RS14280	COG0670	Belongs to the BI1 family
D3W51_RS14285	COG2920	part of a sulfur-relay system
D3W51_RS14290	COG1254	Belongs to the acylphosphatase family
D3W51_RS14305	COG1832	CoA-binding protein
D3W51_RS14320	COG0210	DNA helicase
D3W51_RS14325	COG3304	Inner membrane component domain
D3W51_RS14330	COG1289	transmembrane transporter activity
D3W51_RS14335	COG3070	regulator of competence-specific genes
D3W51_RS14345	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D3W51_RS14345	COG2885	chlorophyll binding
D3W51_RS14355	COG1067	ATP-dependent peptidase activity
D3W51_RS14365	COG3130	regulation of translation
D3W51_RS14370	COG3009	Protein conserved in bacteria
D3W51_RS14375	COG3008	intermembrane lipid transfer
D3W51_RS14375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D3W51_RS14380	COG2995	paraquat-inducible protein a
D3W51_RS14385	COG0488	(ABC) transporter
D3W51_RS14395	COG0633	Ferredoxin
D3W51_RS14395	COG3217	Mosc domain protein beta barrel domain protein
D3W51_RS14410	COG3121	Chaperone
D3W51_RS14415	COG3539	Fimbrial protein
D3W51_RS14420	COG3539	Fimbrial protein
D3W51_RS14425	COG3539	Fimbrial protein
D3W51_RS14430	COG3188	usher protein
D3W51_RS14435	COG3121	Chaperone
D3W51_RS14440	COG3539	Fimbrial protein
D3W51_RS14445	COG0431	NADPH-dependent FMN reductase
D3W51_RS14450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3W51_RS14460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3W51_RS14465	COG1116	anion transmembrane transporter activity
D3W51_RS14470	COG0308	aminopeptidase N
D3W51_RS14490	COG1448	Aminotransferase
D3W51_RS14495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3W51_RS14500	COG3108	Peptidase M15
D3W51_RS14505	COG2989	Protein conserved in bacteria
D3W51_RS14515	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
D3W51_RS14525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3W51_RS14530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D3W51_RS14535	COG3173	Aminoglycoside phosphotransferase
D3W51_RS14550	COG3214	Protein conserved in bacteria
D3W51_RS14555	COG1663	tetraacyldisaccharide 4'-kinase activity
D3W51_RS14560	COG1132	(ABC) transporter
D3W51_RS14565	COG0658	competence protein
D3W51_RS14565	COG2333	competence protein COMEC
D3W51_RS14575	COG0539	negative regulation of cytoplasmic translation
D3W51_RS14585	COG0501	Belongs to the peptidase M48B family
D3W51_RS14600	COG2323	membrane
D3W51_RS14605	COG1944	ATP diphosphatase activity
D3W51_RS14610	COG2116	formate transmembrane transporter activity
D3W51_RS14615	COG1882	Formate acetyltransferase
D3W51_RS14620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3W51_RS14625	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3W51_RS14630	COG0583	DNA-binding transcription factor activity
D3W51_RS14635	COG0531	amino acid
D3W51_RS14645	COG1335	isochorismatase
D3W51_RS14650	COG3302	dmso reductase anchor subunit
D3W51_RS14655	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS14660	COG0243	molybdopterin cofactor binding
D3W51_RS14670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D3W51_RS14680	COG1674	ftsk spoiiie
D3W51_RS14680	COG1178	ABC-type Fe3 transport system permease component
D3W51_RS14685	COG1522	sequence-specific DNA binding
D3W51_RS14690	COG0492	ferredoxin-NADP+ reductase activity
D3W51_RS14695	COG4988	ABC transporter
D3W51_RS14700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D3W51_RS14725	COG0542	response to heat
D3W51_RS14735	COG1278	Cold shock
D3W51_RS14740	COG0577	efflux transmembrane transporter activity
D3W51_RS14740	COG1136	(ABC) transporter
D3W51_RS14745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3W51_RS14750	COG2990	Protein conserved in bacteria
D3W51_RS14755	COG3593	DNA synthesis involved in DNA repair
D3W51_RS14765	COG2431	L-lysine efflux transmembrane transporter activity
D3W51_RS14775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3W51_RS14780	COG0028	Belongs to the TPP enzyme family
D3W51_RS14785	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D3W51_RS14790	COG0702	epimerase
D3W51_RS14795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3W51_RS14800	COG3023	N-Acetylmuramoyl-L-alanine amidase
D3W51_RS14815	COG1126	abc transporter atp-binding protein
D3W51_RS14820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS14825	COG4215	(ABC) transporter
D3W51_RS14830	COG4160	amino acid transport
D3W51_RS14835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS14850	COG1177	transmembrane transport
D3W51_RS14855	COG1176	ABC-type spermidine putrescine transport system, permease component I
D3W51_RS14860	COG3842	ATPase activity
D3W51_RS14865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D3W51_RS14880	COG0778	Nitroreductase
D3W51_RS14925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3W51_RS14980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3W51_RS15095	COG4695	Portal protein
D3W51_RS15105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3W51_RS15140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3W51_RS15180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D3W51_RS15190	COG3226	Transcriptional regulator
D3W51_RS15195	COG0738	Major facilitator superfamily
D3W51_RS15200	COG0561	phosphatase activity
D3W51_RS15210	COG2814	Major facilitator Superfamily
D3W51_RS15215	COG0671	phosphoesterase, PA-phosphatase related
D3W51_RS15220	COG1349	DNA-binding transcription factor activity
D3W51_RS15225	COG1686	Belongs to the peptidase S11 family
D3W51_RS15230	COG0625	glutathione transferase activity
D3W51_RS15235	COG2133	pyrroloquinoline quinone binding
D3W51_RS15250	COG2199	diguanylate cyclase activity
D3W51_RS15255	COG2200	EAL domain
D3W51_RS15260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3W51_RS15270	COG0747	negative chemotaxis
D3W51_RS15275	COG4172	Belongs to the ABC transporter superfamily
D3W51_RS15280	COG1446	asparaginase
D3W51_RS15285	COG0303	'Molybdopterin
D3W51_RS15290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3W51_RS15295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3W51_RS15300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3W51_RS15305	COG1882	Formate acetyltransferase
D3W51_RS15310	COG0561	phosphatase activity
D3W51_RS15320	COG0488	(ABC) transporter
D3W51_RS15325	COG1376	ErfK ybiS ycfS ynhG family protein
D3W51_RS15330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3W51_RS15335	COG1321	iron dependent repressor
D3W51_RS15345	COG2194	sulfuric ester hydrolase activity
D3W51_RS15350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D3W51_RS15360	COG5006	permease, DMT superfamily
D3W51_RS15370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS15375	COG0765	amino acid transport
D3W51_RS15380	COG1126	abc transporter atp-binding protein
D3W51_RS15385	COG0668	transmembrane transport
D3W51_RS15400	COG4774	siderophore transport
D3W51_RS15410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3W51_RS15420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D3W51_RS15425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3W51_RS15430	COG1199	ATP-dependent helicase activity
D3W51_RS15435	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
D3W51_RS15440	COG0513	Belongs to the DEAD box helicase family
D3W51_RS15445	COG1309	transcriptional regulator
D3W51_RS15455	COG1131	(ABC) transporter
D3W51_RS15460	COG0842	Transport permease protein
D3W51_RS15465	COG0842	Transport permease protein
D3W51_RS15475	COG3568	Endonuclease Exonuclease Phosphatase
D3W51_RS15480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3W51_RS15485	COG0392	lysyltransferase activity
D3W51_RS15490	COG0670	Belongs to the BI1 family
D3W51_RS15495	COG0670	Belongs to the BI1 family
D3W51_RS15500	COG0314	molybdopterin synthase activity
D3W51_RS15505	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D3W51_RS15515	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3W51_RS15525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D3W51_RS15535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D3W51_RS15540	COG2226	methyltransferase
D3W51_RS15555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3W51_RS15560	COG1881	PFAM PEBP family protein
D3W51_RS15565	COG2199	diguanylate cyclase activity
D3W51_RS15570	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D3W51_RS15575	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3W51_RS15610	COG1196	nuclear chromosome segregation
D3W51_RS15660	COG1030	water channel activity
D3W51_RS15680	COG4220	transposase activity
D3W51_RS15690	COG5562	phage envelope protein
D3W51_RS15705	COG3772	lysozyme
D3W51_RS15790	COG0582	viral genome integration into host DNA
D3W51_RS15795	COG4677	pectinesterase activity
D3W51_RS15800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3W51_RS15805	COG0471	metal ion transport
D3W51_RS15810	COG2828	Protein conserved in bacteria
D3W51_RS15815	COG0583	DNA-binding transcription factor activity
D3W51_RS15825	COG0561	phosphatase activity
D3W51_RS15830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D3W51_RS15835	COG4149	molybdate abc transporter
D3W51_RS15840	COG0725	ABC transporter, periplasmic molybdate-binding protein
D3W51_RS15850	COG3585	molybdate ion transport
D3W51_RS15850	COG2005	Transcriptional regulator
D3W51_RS15855	COG1119	ATPase activity
D3W51_RS15860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D3W51_RS15865	COG1085	galactose-1-phosphate uridylyltransferase
D3W51_RS15875	COG2017	converts alpha-aldose to the beta-anomer
D3W51_RS15885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D3W51_RS15895	COG1230	cation diffusion facilitator family transporter
D3W51_RS15900	COG3201	nicotinamide mononucleotide transporter
D3W51_RS15950	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D3W51_RS15955	COG2885	chlorophyll binding
D3W51_RS15965	COG3064	Membrane
D3W51_RS15970	COG0848	biopolymer transport protein
D3W51_RS15975	COG0811	peptide transport
D3W51_RS15980	COG0824	Thioesterase
D3W51_RS15985	COG3790	cyd operon protein YbgE
D3W51_RS15990	COG4890	Cyd operon protein YbgT
D3W51_RS15995	COG1294	oxidase, subunit
D3W51_RS16000	COG1271	oxidase subunit
D3W51_RS16010	COG0383	alpha-mannosidase activity
D3W51_RS16015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS16015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS16015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS16020	COG2188	Transcriptional regulator
D3W51_RS16025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3W51_RS16035	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3W51_RS16040	COG0567	Dehydrogenase, E1 component
D3W51_RS16045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3W51_RS16050	COG1053	succinate dehydrogenase
D3W51_RS16055	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D3W51_RS16060	COG2009	succinate dehydrogenase
D3W51_RS16070	COG0372	Belongs to the citrate synthase family
D3W51_RS16075	COG3539	Fimbrial protein
D3W51_RS16080	COG3188	usher protein
D3W51_RS16085	COG3121	Chaperone
D3W51_RS16090	COG3539	Fimbrial protein
D3W51_RS16095	COG3180	Ammonia monooxygenase
D3W51_RS16110	COG1984	allophanate hydrolase subunit 2
D3W51_RS16115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D3W51_RS16120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D3W51_RS16125	COG3104	oligopeptide transport
D3W51_RS16130	COG0415	Belongs to the DNA photolyase family
D3W51_RS16135	COG3272	Protein of unknown function (DUF1722)
D3W51_RS16170	COG3209	COG3209 Rhs family protein
D3W51_RS16200	COG2205	protein histidine kinase activity
D3W51_RS16205	COG0745	RESPONSE REGULATOR receiver
D3W51_RS16215	COG1982	Orn Lys Arg decarboxylase major
D3W51_RS16220	COG0531	amino acid
D3W51_RS16240	COG0033	Phosphoglucomutase
D3W51_RS16245	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
D3W51_RS16250	COG0596	Alpha beta hydrolase
D3W51_RS16260	COG0716	FMN binding
D3W51_RS16270	COG0735	belongs to the Fur family
D3W51_RS16290	COG2190	(PTS) system
D3W51_RS16290	COG1263	PTS System
D3W51_RS16290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS16300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3W51_RS16305	COG1846	Transcriptional regulator
D3W51_RS16305	COG1940	carbohydrate kinase activity
D3W51_RS16310	COG0647	UMP catabolic process
D3W51_RS16315	COG0367	asparagine synthase
D3W51_RS16355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3W51_RS16365	COG1702	phosphate starvation-inducible protein PhoH
D3W51_RS16375	COG4535	Mg2 and Co2 transporter CorC
D3W51_RS16380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D3W51_RS16385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3W51_RS16390	COG0765	amino acid transport
D3W51_RS16395	COG0765	amino acid transport
D3W51_RS16400	COG1126	abc transporter atp-binding protein
D3W51_RS16415	COG2214	Heat shock protein DnaJ domain protein
D3W51_RS16425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D3W51_RS16430	COG2214	Heat shock protein DnaJ domain protein
D3W51_RS16450	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D3W51_RS16455	COG2888	peptidyl-tyrosine sulfation
D3W51_RS16470	COG1466	dna polymerase III delta subunit
D3W51_RS16480	COG0406	alpha-ribazole phosphatase activity
D3W51_RS16485	COG0799	negative regulation of ribosome biogenesis
D3W51_RS16495	COG0768	penicillin binding
D3W51_RS16500	COG0772	Belongs to the SEDS family
D3W51_RS16505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3W51_RS16510	COG1686	Belongs to the peptidase S11 family
D3W51_RS16525	COG0583	DNA-binding transcription factor activity
D3W51_RS16535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3W51_RS16560	COG3069	C4-dicarboxylate transmembrane transporter activity
D3W51_RS16565	COG4565	transcriptional regulatory protein
D3W51_RS16570	COG3290	protein histidine kinase activity
D3W51_RS16575	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
D3W51_RS16585	COG2301	Belongs to the HpcH HpaI aldolase family
D3W51_RS16590	COG3051	citrate lyase alpha subunit
D3W51_RS16605	COG0471	metal ion transport
D3W51_RS16610	COG3719	Belongs to the RNase T2 family
D3W51_RS16615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3W51_RS16620	COG1063	alcohol dehydrogenase
D3W51_RS16625	COG0589	response to stress
D3W51_RS16630	COG3634	alkyl hydroperoxide reductase activity
D3W51_RS16635	COG0450	alkyl hydroperoxide reductase
D3W51_RS16640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3W51_RS16690	COG3969	phosphoadenosine phosphosulfate
D3W51_RS16695	COG1475	DNA binding
D3W51_RS16700	COG0436	Aminotransferase
D3W51_RS16705	COG0371	Dehydrogenase
D3W51_RS16710	COG2879	small protein
D3W51_RS16715	COG1966	Carbon starvation protein
D3W51_RS16720	COG2050	protein possibly involved in aromatic compounds catabolism
D3W51_RS16725	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS16730	COG3433	isochorismatase activity
D3W51_RS16730	COG1535	isochorismatase
D3W51_RS16735	COG1021	2,3-dihydroxybenzoate-AMP ligase
D3W51_RS16740	COG1169	isochorismate synthase
D3W51_RS16745	COG4592	Periplasmic binding protein
D3W51_RS16755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3W51_RS16760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3W51_RS16765	COG1120	ATPase activity
D3W51_RS16770	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
D3W51_RS16775	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D3W51_RS16775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3W51_RS16780	COG3251	PFAM MbtH domain protein
D3W51_RS16785	COG2382	esterase
D3W51_RS16790	COG4771	TonB-dependent receptor
D3W51_RS16795	COG2977	Belongs to the P-Pant transferase superfamily
D3W51_RS16800	COG3385	transposase activity
D3W51_RS16825	COG2315	Protein conserved in bacteria
D3W51_RS16830	COG0778	Nitroreductase
D3W51_RS16835	COG0668	transmembrane transport
D3W51_RS16840	COG1113	amino acid transport
D3W51_RS16845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3W51_RS16850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3W51_RS16855	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3W51_RS16860	COG1538	Outer membrane efflux protein
D3W51_RS16865	COG0745	RESPONSE REGULATOR receiver
D3W51_RS16870	COG5002	protein histidine kinase activity
D3W51_RS16880	COG4783	chaperone-mediated protein folding
D3W51_RS16890	COG2207	Transcriptional regulator
D3W51_RS16900	COG2197	response regulator
D3W51_RS16905	COG3539	Fimbrial protein
D3W51_RS16910	COG3539	Fimbrial protein
D3W51_RS16915	COG3188	usher protein
D3W51_RS16935	COG3539	Fimbrial protein
D3W51_RS16945	COG2501	S4 domain
D3W51_RS16950	COG1988	membrane-bound metal-dependent
D3W51_RS16960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3W51_RS16970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D3W51_RS16975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D3W51_RS16980	COG0549	Belongs to the carbamate kinase family
D3W51_RS16990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3W51_RS16995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3W51_RS17000	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D3W51_RS17005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3W51_RS17010	COG3257	ureidoglycine aminohydrolase activity
D3W51_RS17015	COG1929	Belongs to the glycerate kinase type-1 family
D3W51_RS17020	COG2233	PERMEase
D3W51_RS17030	COG1953	Uracil, thiamine, allantoin
D3W51_RS17035	COG2084	Dehydrogenase
D3W51_RS17040	COG3622	Belongs to the hyi family
D3W51_RS17045	COG3960	tartronate-semialdehyde synthase activity
D3W51_RS17050	COG1414	Transcriptional regulator
D3W51_RS17060	COG0583	DNA-binding transcription factor activity
D3W51_RS17095	COG3209	COG3209 Rhs family protein
D3W51_RS17100	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D3W51_RS17105	COG4181	ATPase activity
D3W51_RS17110	COG2755	lipolytic protein G-D-S-L family
D3W51_RS17115	COG0300	oxidoreductase activity
D3W51_RS17120	COG3118	belongs to the thioredoxin family
D3W51_RS17125	COG0390	transport system, permease component
D3W51_RS17130	COG4619	ABC transporter
D3W51_RS17135	COG0330	HflC and HflK could
D3W51_RS17140	COG1585	Membrane protein implicated in regulation of membrane protease activity
D3W51_RS17145	COG0789	Transcriptional regulator
D3W51_RS17150	COG0531	amino acid
D3W51_RS17155	COG2066	Belongs to the glutaminase family
D3W51_RS17160	COG2217	Heavy metal translocating P-type atpase
D3W51_RS17165	COG3093	addiction module antidote protein HigA
D3W51_RS17175	COG3735	TraB family
D3W51_RS17180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3W51_RS17185	COG0737	Belongs to the 5'-nucleotidase family
D3W51_RS17190	COG2223	nitrite transmembrane transporter activity
D3W51_RS17195	COG4651	solute:proton antiporter activity
D3W51_RS17195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3W51_RS17200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS17235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D3W51_RS17245	COG2832	Protein of unknown function (DUF454)
D3W51_RS17250	COG3923	Primosomal replication protein n
D3W51_RS17260	COG3264	Mechanosensitive ion channel
D3W51_RS17260	COG1196	nuclear chromosome segregation
D3W51_RS17265	COG1309	transcriptional regulator
D3W51_RS17270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3W51_RS17275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3W51_RS17290	COG0110	maltose O-acetyltransferase activity
D3W51_RS17300	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D3W51_RS17305	COG5507	3-demethylubiquinone-9 3-methyltransferase
D3W51_RS17315	COG3695	enzyme binding
D3W51_RS17320	COG3126	Type III secretion system lipoprotein chaperone (YscW)
D3W51_RS17325	COG1946	Acyl-CoA thioesterase
D3W51_RS17330	COG0004	ammonium transporteR
D3W51_RS17335	COG0347	Belongs to the P(II) protein family
D3W51_RS17340	COG1132	(ABC) transporter
D3W51_RS17345	COG1132	(ABC) transporter
D3W51_RS17350	COG1522	sequence-specific DNA binding
D3W51_RS17360	COG4533	DNA binding
D3W51_RS17370	COG0824	Thioesterase
D3W51_RS17375	COG1555	photosystem II stabilization
D3W51_RS17380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3W51_RS17385	COG0776	regulation of translation
D3W51_RS17390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D3W51_RS17415	COG0271	Belongs to the BolA IbaG family
D3W51_RS17420	COG3056	Lipoprotein
D3W51_RS17425	COG2223	nitrite transmembrane transporter activity
D3W51_RS17430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3W51_RS17435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3W51_RS17440	COG1845	cytochrome c oxidase, subunit III
D3W51_RS17445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3W51_RS17455	COG2814	Major facilitator Superfamily
D3W51_RS17465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3W51_RS17470	COG0693	protein deglycase activity
D3W51_RS17485	COG0142	geranyltranstransferase activity
D3W51_RS17500	COG0667	Aldo Keto reductase
D3W51_RS17505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D3W51_RS17510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D3W51_RS17525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3W51_RS17525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3W51_RS17535	COG4238	major outer membrane lipoprotein
D3W51_RS17540	COG3248	Nucleoside-binding outer membrane protein
D3W51_RS17545	COG1403	HNH endonuclease
D3W51_RS17550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3W51_RS17555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3W51_RS17560	COG1862	Preprotein translocase
D3W51_RS17580	COG0366	Alpha amylase catalytic
D3W51_RS17585	COG1113	amino acid transport
D3W51_RS17590	COG1114	Component of the transport system for branched-chain amino acids
D3W51_RS17595	COG5002	protein histidine kinase activity
D3W51_RS17600	COG0745	RESPONSE REGULATOR receiver
D3W51_RS17605	COG0420	3'-5' exonuclease activity
D3W51_RS17610	COG0419	ATPase involved in DNA repair
D3W51_RS17615	COG2814	Major facilitator Superfamily
D3W51_RS17620	COG1940	carbohydrate kinase activity
D3W51_RS17645	COG4126	flavin adenine dinucleotide binding
D3W51_RS17665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3W51_RS17670	COG3706	GGDEF domain
D3W51_RS17680	COG1785	Belongs to the alkaline phosphatase family
D3W51_RS17690	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3W51_RS17710	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
D3W51_RS17715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3W51_RS17720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3W51_RS17725	COG3468	outer membrane autotransporter barrel domain protein
D3W51_RS17735	COG0113	porphobilinogen synthase activity
D3W51_RS17740	COG2175	clavaminate synthase activity
D3W51_RS17745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3W51_RS17755	COG4521	taurine ABC transporter
D3W51_RS17760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3W51_RS17765	COG1215	transferase activity, transferring glycosyl groups
D3W51_RS17795	COG3122	Protein conserved in bacteria
D3W51_RS17800	COG2814	Major facilitator Superfamily
D3W51_RS17815	COG3971	2-oxopent-4-enoate hydratase activity
D3W51_RS17835	COG1414	Transcriptional regulator
D3W51_RS17840	COG1609	Transcriptional regulator
D3W51_RS17845	COG3250	beta-galactosidase activity
D3W51_RS17850	COG2223	nitrite transmembrane transporter activity
D3W51_RS17855	COG0110	maltose O-acetyltransferase activity
D3W51_RS17860	COG2807	transmembrane transport
D3W51_RS17870	COG0288	reversible hydration of carbon dioxide
D3W51_RS17875	COG0583	DNA-binding transcription factor activity
D3W51_RS17880	COG0402	S-adenosylhomocysteine deaminase activity
D3W51_RS17885	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D3W51_RS17890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3W51_RS17895	COG2079	MmgE PrpD family protein
D3W51_RS17900	COG0372	Belongs to the citrate synthase family
D3W51_RS17905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D3W51_RS17910	COG3829	transcription factor binding
D3W51_RS17920	COG1280	lysine exporter protein (LysE YggA)
D3W51_RS17935	COG1064	alcohol dehydrogenase
D3W51_RS17940	COG0402	S-adenosylhomocysteine deaminase activity
D3W51_RS17945	COG0549	Belongs to the carbamate kinase family
D3W51_RS17955	COG1304	FMN binding
D3W51_RS17960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3W51_RS17970	COG0666	response to abiotic stimulus
D3W51_RS17980	COG0583	DNA-binding transcription factor activity
D3W51_RS17985	COG2771	luxR family
D3W51_RS17985	COG2200	EAL domain
D3W51_RS17995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3W51_RS18020	COG1556	Lactate utilization protein
D3W51_RS18025	COG1139	Iron-sulfur cluster binding protein
D3W51_RS18030	COG0247	lactate metabolic process
D3W51_RS18035	COG2207	Transcriptional regulator
D3W51_RS18040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3W51_RS18050	COG3059	membrane
D3W51_RS18060	COG3708	Transcriptional regulator
D3W51_RS18060	COG2207	Transcriptional regulator
D3W51_RS18115	COG3188	usher protein
D3W51_RS18125	COG3121	Chaperone
D3W51_RS18130	COG0727	PFAM Uncharacterised protein family (UPF0153)
D3W51_RS18135	COG3477	response to acidic pH
D3W51_RS18140	COG2080	2 iron, 2 sulfur cluster binding
D3W51_RS18145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D3W51_RS18150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D3W51_RS18155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D3W51_RS18160	COG0583	DNA-binding transcription factor activity
D3W51_RS18200	COG2003	Belongs to the UPF0758 family
D3W51_RS18225	COG3468	outer membrane autotransporter barrel domain protein
D3W51_RS18260	COG1874	Beta-galactosidase
D3W51_RS18265	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D3W51_RS18270	COG3833	ABC-type maltose transport systems, permease component
D3W51_RS18275	COG1175	transmembrane transport
D3W51_RS18280	COG2182	Extracellular solute-binding protein
D3W51_RS18300	COG4581	dead DEAH box helicase
D3W51_RS18335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3W51_RS18345	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D3W51_RS18355	COG3778	Protein conserved in bacteria
D3W51_RS18360	COG3299	homolog of phage Mu protein gp47
D3W51_RS18380	COG4228	DNA circulation
D3W51_RS18405	COG4386	tail sheath protein
D3W51_RS18450	COG4695	Portal protein
D3W51_RS18460	COG4626	Terminase
D3W51_RS18460	COG1802	Transcriptional regulator
D3W51_RS18500	COG0484	heat shock protein binding
D3W51_RS18505	COG1403	HNH endonuclease
D3W51_RS18515	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D3W51_RS18525	COG4725	Belongs to the MT-A70-like family
D3W51_RS18535	COG1846	Transcriptional regulator
D3W51_RS18560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3W51_RS18585	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
D3W51_RS18605	COG0582	viral genome integration into host DNA
D3W51_RS18625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D3W51_RS18645	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3W51_RS18650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D3W51_RS18655	COG1690	Belongs to the RtcB family
D3W51_RS18660	COG0454	-acetyltransferase
D3W51_RS18670	COG2161	toxin-antitoxin pair type II binding
D3W51_RS18690	COG1943	Transposase
D3W51_RS18695	COG0791	NLP P60 protein
D3W51_RS18700	COG3077	Addiction module antitoxin, RelB DinJ family
D3W51_RS18705	COG3041	Addiction module toxin RelE StbE family
D3W51_RS18710	COG3034	peptidoglycan biosynthetic process
D3W51_RS18715	COG0121	glutamine amidotransferase
D3W51_RS18725	COG1960	acyl-CoA dehydrogenase activity
D3W51_RS18735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3W51_RS18750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3W51_RS18760	COG2226	methyltransferase
D3W51_RS18770	COG0741	lytic transglycosylase activity
D3W51_RS18770	COG1388	LysM domain
D3W51_RS18775	COG2226	methyltransferase
D3W51_RS18785	COG0583	DNA-binding transcription factor activity
D3W51_RS18790	COG0656	L-ascorbic acid biosynthetic process
D3W51_RS18825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D3W51_RS18830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3W51_RS18835	COG2011	ABC-type metal ion transport system permease component
D3W51_RS18840	COG1464	Belongs to the NlpA lipoprotein family
D3W51_RS18850	COG1720	tRNA m6t6A37 methyltransferase activity
D3W51_RS18860	COG0791	NLP P60 protein
D3W51_RS18865	COG3015	lipoprotein NlpE involved in copper resistance
D3W51_RS18870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D3W51_RS18875	COG4681	YaeQ
D3W51_RS18885	COG4568	rho-dependent transcription termination
D3W51_RS18890	COG0037	tRNA processing
D3W51_RS18895	COG0346	lactoylglutathione lyase activity
D3W51_RS18900	COG1982	Orn Lys Arg decarboxylase major
D3W51_RS18910	COG0587	DNA-directed DNA polymerase activity
D3W51_RS18935	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3W51_RS18940	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
D3W51_RS18950	COG0750	zinc metalloprotease
D3W51_RS18955	COG0575	Belongs to the CDS family
D3W51_RS18960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3W51_RS18965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D3W51_RS18990	COG0024	Methionine aminopeptidase
D3W51_RS19005	COG1408	metallophosphoesterase
D3W51_RS19020	COG3835	regulator
D3W51_RS19025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3W51_RS19040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3W51_RS19045	COG2860	membrane
D3W51_RS19070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3W51_RS19075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3W51_RS19080	COG1120	ATPase activity
D3W51_RS19085	COG4774	siderophore transport
D3W51_RS19090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3W51_RS19095	COG1643	Atp-dependent helicase
D3W51_RS19100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3W51_RS19110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3W51_RS19120	COG0617	tRNA 3'-terminal CCA addition
D3W51_RS19125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3W51_RS19135	COG3039	Transposase
D3W51_RS19155	COG5464	transposase or invertase
D3W51_RS19165	COG0726	polysaccharide deacetylase
D3W51_RS19170	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS19175	COG0842	Transport permease protein
D3W51_RS19180	COG1131	(ABC) transporter
D3W51_RS19185	COG0288	reversible hydration of carbon dioxide
D3W51_RS19190	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D3W51_RS19195	COG4993	Dehydrogenase
D3W51_RS19200	COG2132	Multicopper oxidase
D3W51_RS19225	COG1049	propionate catabolic process, 2-methylcitrate cycle
D3W51_RS19230	COG3064	Membrane
D3W51_RS19235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3W51_RS19240	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3W51_RS19245	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D3W51_RS19250	COG2186	Transcriptional regulator
D3W51_RS19255	COG1113	amino acid transport
D3W51_RS19260	COG3725	Membrane protein required for beta-lactamase induction
D3W51_RS19265	COG3023	N-Acetylmuramoyl-L-alanine amidase
D3W51_RS19270	COG0157	Belongs to the NadC ModD family
D3W51_RS19275	COG4969	Belongs to the N-Me-Phe pilin family
D3W51_RS19280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3W51_RS19285	COG1459	type II secretion system
D3W51_RS19295	COG0237	dephospho-CoA kinase activity
D3W51_RS19310	COG0494	nUDIX hydrolase
D3W51_RS19330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D3W51_RS19335	COG0849	cell division
D3W51_RS19340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D3W51_RS19345	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3W51_RS19360	COG0772	Belongs to the SEDS family
D3W51_RS19365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3W51_RS19375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D3W51_RS19380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3W51_RS19385	COG0768	penicillin binding
D3W51_RS19390	COG3116	cell division
D3W51_RS19400	COG2001	Belongs to the MraZ family
D3W51_RS19405	COG1609	Transcriptional regulator
D3W51_RS19415	COG0440	acetolactate synthase activity
D3W51_RS19420	COG0028	Belongs to the TPP enzyme family
D3W51_RS19430	COG0583	DNA-binding transcription factor activity
D3W51_RS19445	COG0473	3-isopropylmalate dehydrogenase activity
D3W51_RS19460	COG2814	Major facilitator Superfamily
D3W51_RS19470	COG4533	DNA binding
D3W51_RS19475	COG4143	(ABC) transporter
D3W51_RS19480	COG1178	ABC-type Fe3 transport system permease component
D3W51_RS19485	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
D3W51_RS19490	COG0586	Pfam SNARE associated Golgi protein
D3W51_RS19495	COG4977	sequence-specific DNA binding
D3W51_RS19500	COG1069	ribulokinase activity
D3W51_RS19505	COG2160	L-arabinose isomerase activity
D3W51_RS19510	COG0235	Class ii aldolase
D3W51_RS19515	COG0417	DNA replication proofreading
D3W51_RS19525	COG0564	pseudouridine synthase activity
D3W51_RS19535	COG1357	PFAM Pentapeptide repeats (8 copies)
D3W51_RS19540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D3W51_RS19545	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D3W51_RS19550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3W51_RS19575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3W51_RS19590	COG2271	Major facilitator Superfamily
D3W51_RS19595	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D3W51_RS19600	COG0644	oxidoreductase
D3W51_RS19650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3W51_RS19655	COG0505	Belongs to the CarA family
D3W51_RS19675	COG1047	Peptidyl-prolyl cis-trans
D3W51_RS19690	COG0196	riboflavin kinase activity
D3W51_RS19730	COG0583	DNA-binding transcription factor activity
D3W51_RS19745	COG3385	transposase activity
D3W51_RS19765	COG4735	regulation of single-species biofilm formation
D3W51_RS19770	COG1584	GPR1 FUN34 yaaH family protein
D3W51_RS19775	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3W51_RS19785	COG1115	amino acid carrier protein
D3W51_RS19800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D3W51_RS19810	COG0527	aspartate kinase activity
D3W51_RS19810	COG0460	homoserine dehydrogenase
D3W51_RS19820	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D3W51_RS19830	COG0745	RESPONSE REGULATOR receiver
D3W51_RS19835	COG4452	Inner membrane protein CreD
D3W51_RS19840	COG2205	protein histidine kinase activity
D3W51_RS19845	COG0745	RESPONSE REGULATOR receiver
D3W51_RS19850	COG3045	CreA protein
D3W51_RS19855	COG3708	Transcriptional regulator
D3W51_RS19855	COG2207	Transcriptional regulator
D3W51_RS19875	COG0741	lytic transglycosylase activity
D3W51_RS19880	COG0488	(ABC) transporter
D3W51_RS19885	COG3172	ATPase kinase involved in NAD metabolism
D3W51_RS19885	COG1056	cytidyltransferase-related domain
D3W51_RS19890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D3W51_RS19895	COG0560	Phosphoserine phosphatase
D3W51_RS19900	COG3726	membrane protein affecting hemolysin expression
D3W51_RS19935	COG1328	CTP reductase activity
D3W51_RS19940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3W51_RS19945	COG0084	hydrolase, TatD family'
D3W51_RS19950	COG4667	esterase of the alpha-beta hydrolase superfamily
D3W51_RS19960	COG2823	Periplasmic or secreted lipoprotein
D3W51_RS19970	COG1011	Hydrolase
D3W51_RS19975	COG0456	acetyltransferase
D3W51_RS19980	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
D3W51_RS20010	COG4114	ferric iron reductase
D3W51_RS20015	COG2197	response regulator
D3W51_RS20020	COG2197	response regulator
D3W51_RS20025	COG2966	Psort location CytoplasmicMembrane, score
D3W51_RS20040	COG1484	DNA-dependent DNA replication
D3W51_RS20055	COG1063	alcohol dehydrogenase
D3W51_RS20060	COG1802	Transcriptional regulator
D3W51_RS20085	COG0840	transmembrane signaling receptor activity
D3W51_RS20090	COG1846	Transcriptional regulator
D3W51_RS20095	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3W51_RS20100	COG1012	belongs to the aldehyde dehydrogenase family
D3W51_RS20105	COG3384	dioxygenase
D3W51_RS20115	COG3971	2-oxopent-4-enoate hydratase activity
D3W51_RS20140	COG2368	4-hydroxyphenylacetate
D3W51_RS20145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3W51_RS20150	COG1966	Carbon starvation protein
D3W51_RS20155	COG2879	small protein
D3W51_RS20160	COG0523	cobalamin synthesis protein
D3W51_RS20210	COG5457	Domain of unknown function (DUF1127)
D3W51_RS20215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3W51_RS20230	COG2814	Major facilitator Superfamily
D3W51_RS20235	COG2733	membrane
D3W51_RS20240	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
D3W51_RS20245	COG1924	4 iron, 4 sulfur cluster binding
D3W51_RS20260	COG0477	Major facilitator Superfamily
D3W51_RS20270	COG3366	ferrous iron transmembrane transporter activity
D3W51_RS20275	COG0700	Nucleoside recognition
D3W51_RS20280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3W51_RS20285	COG0583	DNA-binding transcription factor activity
D3W51_RS20305	COG2186	Transcriptional regulator
D3W51_RS20310	COG0246	Mannitol dehydrogenase
D3W51_RS20325	COG3539	Fimbrial protein
D3W51_RS20330	COG3539	Fimbrial protein
D3W51_RS20335	COG3539	Fimbrial protein
D3W51_RS20340	COG3188	usher protein
D3W51_RS20345	COG3121	Chaperone
D3W51_RS20350	COG3539	Fimbrial protein
D3W51_RS20360	COG4974	Belongs to the 'phage' integrase family
D3W51_RS20365	COG0582	viral genome integration into host DNA
D3W51_RS20370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D3W51_RS20375	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
D3W51_RS20425	COG0582	viral genome integration into host DNA
D3W51_RS20435	COG1064	alcohol dehydrogenase
D3W51_RS20440	COG0433	COG0433 Predicted ATPase
D3W51_RS20445	COG0795	lipopolysaccharide-transporting ATPase activity
D3W51_RS20450	COG0795	lipopolysaccharide-transporting ATPase activity
D3W51_RS20460	COG2927	DNA polymerase III (CHI subunit)
D3W51_RS20465	COG0525	valine-tRNA ligase activity
D3W51_RS20470	COG4269	membrane
D3W51_RS20475	COG0456	acetyltransferase
D3W51_RS20480	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
D3W51_RS20495	COG2731	YhcH YjgK YiaL family protein
D3W51_RS20500	COG1309	transcriptional regulator
D3W51_RS20505	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS20510	COG0251	oxidation-reduction process
D3W51_RS20530	COG0251	oxidation-reduction process
D3W51_RS20535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D3W51_RS20545	COG1609	Transcriptional regulator
D3W51_RS20550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS20550	COG1263	PTS System
D3W51_RS20555	COG0366	Alpha amylase catalytic
D3W51_RS20560	COG1328	CTP reductase activity
D3W51_RS20565	COG0602	queuosine metabolic process
D3W51_RS20570	COG3783	Cytochrome b(562)
D3W51_RS20575	COG0312	modulator of DNA gyrase
D3W51_RS20585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3W51_RS20595	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3W51_RS20600	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3W51_RS20605	COG1129	ABC transporter
D3W51_RS20610	COG1879	ABC-type sugar transport system periplasmic component
D3W51_RS20615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D3W51_RS20625	COG2105	PFAM AIG2 family protein
D3W51_RS20630	COG2911	Protein conserved in bacteria
D3W51_RS20635	COG0729	surface antigen
D3W51_RS20645	COG1253	flavin adenine dinucleotide binding
D3W51_RS20655	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D3W51_RS20660	COG1218	3'(2'),5'-bisphosphate nucleotidase
D3W51_RS20665	COG0737	Belongs to the 5'-nucleotidase family
D3W51_RS20670	COG1733	regulation of RNA biosynthetic process
D3W51_RS20675	COG0702	epimerase
D3W51_RS20680	COG0697	spore germination
D3W51_RS20690	COG1113	amino acid transport
D3W51_RS20695	COG0545	Peptidyl-prolyl cis-trans isomerase
D3W51_RS20705	COG3061	Opacity-associated protein A
D3W51_RS20710	COG1309	transcriptional regulator
D3W51_RS20715	COG1028	Short-chain dehydrogenase reductase Sdr
D3W51_RS20725	COG1024	Enoyl-CoA hydratase
D3W51_RS20730	COG4670	ketone body catabolic process
D3W51_RS20735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D3W51_RS20740	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D3W51_RS20750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3W51_RS20760	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D3W51_RS20800	COG3414	Phosphotransferase system galactitol-specific IIB component
D3W51_RS20805	COG3037	sugar-specific permease SgaT UlaA
D3W51_RS20820	COG1073	alpha beta
D3W51_RS20825	COG3650	response to hydrogen peroxide
D3W51_RS20835	COG1960	acyl-CoA dehydrogenase activity
D3W51_RS20840	COG0754	glutathionylspermidine amidase activity
D3W51_RS20845	COG5463	Belongs to the UPF0441 family
D3W51_RS20850	COG3766	membrane
D3W51_RS20860	COG1842	Phage shock protein A
D3W51_RS20865	COG3789	protein conserved in bacteria
D3W51_RS20870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3W51_RS20875	COG0557	exoribonuclease II activity
D3W51_RS20890	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
D3W51_RS20895	COG0330	HflC and HflK could
D3W51_RS20900	COG0330	HflC and HflK could
D3W51_RS20905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3W51_RS20925	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3W51_RS20930	COG0802	atpase or kinase
D3W51_RS20940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3W51_RS20980	COG1511	domain protein
D3W51_RS20980	COG3264	Mechanosensitive ion channel
D3W51_RS20995	COG0531	amino acid
D3W51_RS21005	COG1053	succinate dehydrogenase
D3W51_RS21010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3W51_RS21025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3W51_RS21030	COG3040	lipid binding
D3W51_RS21035	COG2076	Multidrug Resistance protein
D3W51_RS21040	COG5510	response to toxic substance
D3W51_RS21045	COG5510	response to toxic substance
D3W51_RS21055	COG1509	lysine 2,3-aminomutase activity
D3W51_RS21080	COG0531	amino acid
D3W51_RS21085	COG3030	protein affecting phage T7 exclusion by the F plasmid
D3W51_RS21090	COG1027	Aspartate ammonia-lyase
D3W51_RS21095	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D3W51_RS21105	COG4232	protein-disulfide reductase activity
D3W51_RS21110	COG1309	transcriptional regulator
D3W51_RS21120	COG3710	Transcriptional regulator
D3W51_RS21125	COG0531	amino acid
D3W51_RS21130	COG1982	Orn Lys Arg decarboxylase major
D3W51_RS21135	COG3104	oligopeptide transport
D3W51_RS21140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3W51_RS21155	COG2388	GCN5-related N-acetyl-transferase
D3W51_RS21160	COG3592	Divergent 4Fe-4S mono-cluster
D3W51_RS21165	COG3290	protein histidine kinase activity
D3W51_RS21170	COG4565	transcriptional regulatory protein
D3W51_RS21175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D3W51_RS21180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D3W51_RS21180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D3W51_RS21185	COG3647	Membrane
D3W51_RS21190	COG2211	Major facilitator Superfamily
D3W51_RS21195	COG1486	melibiose metabolic process
D3W51_RS21200	COG2169	Transcriptional regulator
D3W51_RS21205	COG1982	Orn Lys Arg decarboxylase major
D3W51_RS21210	COG2207	Transcriptional regulator
D3W51_RS21215	COG0531	amino acid
D3W51_RS21220	COG2194	sulfuric ester hydrolase activity
D3W51_RS21225	COG0745	RESPONSE REGULATOR receiver
D3W51_RS21230	COG0642	Histidine kinase
D3W51_RS21240	COG0477	Major facilitator Superfamily
D3W51_RS21250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3W51_RS21255	COG2824	Alkylphosphonate utilization operon protein PhnA
D3W51_RS21260	COG2764	glyoxalase bleomycin resistance protein dioxygenase
D3W51_RS21265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D3W51_RS21275	COG1566	PFAM secretion protein HlyD family protein
D3W51_RS21280	COG1289	transmembrane transporter activity
D3W51_RS21285	COG1538	Outer membrane efflux protein
D3W51_RS21295	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D3W51_RS21300	COG1301	dicarboxylic acid transport
D3W51_RS21305	COG4235	cytochrome complex assembly
D3W51_RS21310	COG3088	subunit of a heme lyase
D3W51_RS21315	COG1138	Cytochrome C-type biogenesis protein
D3W51_RS21320	COG3301	Polysulphide reductase, NrfD
D3W51_RS21325	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS21330	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
D3W51_RS21340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3W51_RS21345	COG3162	membrane
D3W51_RS21355	COG1357	PFAM Pentapeptide repeats (8 copies)
D3W51_RS21360	COG0025	NhaP-type Na H and K H
D3W51_RS21365	COG2252	PERMEase
D3W51_RS21370	COG0789	Transcriptional regulator
D3W51_RS21375	COG2207	Transcriptional regulator
D3W51_RS21380	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D3W51_RS21390	COG0629	single-stranded DNA binding
D3W51_RS21395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3W51_RS21400	COG2315	Protein conserved in bacteria
D3W51_RS21405	COG0432	Pfam Uncharacterised protein family UPF0047
D3W51_RS21410	COG3700	Belongs to the class B bacterial acid phosphatase family
D3W51_RS21420	COG1448	Aminotransferase
D3W51_RS21425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3W51_RS21430	COG0305	Participates in initiation and elongation during chromosome replication
D3W51_RS21435	COG0604	alcohol dehydrogenase
D3W51_RS21445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3W51_RS21460	COG0735	belongs to the Fur family
D3W51_RS21465	COG3237	CsbD-like
D3W51_RS21470	COG0534	Mate efflux family protein
D3W51_RS21480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D3W51_RS21515	COG3842	ATPase activity
D3W51_RS21520	COG2182	Extracellular solute-binding protein
D3W51_RS21525	COG1175	transmembrane transport
D3W51_RS21530	COG3833	ABC-type maltose transport systems, permease component
D3W51_RS21535	COG0477	Major facilitator Superfamily
D3W51_RS21535	COG2814	Major facilitator Superfamily
D3W51_RS21550	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3W51_RS21580	COG0527	aspartate kinase activity
D3W51_RS21590	COG1187	pseudouridine synthase activity
D3W51_RS21600	COG1283	sodium-dependent phosphate transmembrane transporter activity
D3W51_RS21605	COG1410	methionine synthase
D3W51_RS21605	COG0646	methionine synthase
D3W51_RS21610	COG1414	Transcriptional regulator
D3W51_RS21630	COG2224	Isocitrate lyase
D3W51_RS21635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D3W51_RS21645	COG0456	acetyltransferase
D3W51_RS21680	COG0151	Belongs to the GarS family
D3W51_RS21685	COG2204	response regulator
D3W51_RS21690	COG4191	Histidine kinase
D3W51_RS21695	COG3678	ATP-independent chaperone mediated protein folding
D3W51_RS21710	COG3068	Protein conserved in bacteria
D3W51_RS21745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3W51_RS21750	COG2104	thiamine diphosphate biosynthetic process
D3W51_RS21760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D3W51_RS21800	COG0250	Participates in transcription elongation, termination and antitermination
D3W51_RS21805	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3W51_RS21840	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D3W51_RS21840	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D3W51_RS21845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D3W51_RS21875	COG4206	TonB-dependent receptor
D3W51_RS21890	COG1309	transcriptional regulator
D3W51_RS21900	COG0583	DNA-binding transcription factor activity
D3W51_RS21915	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D3W51_RS21935	COG2194	sulfuric ester hydrolase activity
D3W51_RS21940	COG2207	Transcriptional regulator
D3W51_RS21945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS21950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3W51_RS21955	COG1882	Formate acetyltransferase
D3W51_RS21960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS21965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS21970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS21970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS21970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3W51_RS21975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3W51_RS21980	COG0371	Dehydrogenase
D3W51_RS21985	COG3738	Protein conserved in bacteria
D3W51_RS22000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D3W51_RS22005	COG0460	homoserine dehydrogenase
D3W51_RS22005	COG0527	aspartate kinase activity
D3W51_RS22010	COG0626	cystathionine gamma-synthase activity
D3W51_RS22020	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D3W51_RS22030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3W51_RS22035	COG1609	Transcriptional regulator
D3W51_RS22040	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3W51_RS22055	COG1575	Belongs to the MenA family. Type 1 subfamily
D3W51_RS22070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D3W51_RS22080	COG1494	fructose-1,6-bisphosphatase
D3W51_RS22085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3W51_RS22090	COG0589	response to stress
D3W51_RS22095	COG3691	Protein conserved in bacteria
D3W51_RS22100	COG3152	Membrane
D3W51_RS22120	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D3W51_RS22135	COG3678	ATP-independent chaperone mediated protein folding
D3W51_RS22140	COG0745	RESPONSE REGULATOR receiver
D3W51_RS22145	COG2205	protein histidine kinase activity
D3W51_RS22150	COG2258	MOSC domain
D3W51_RS22160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3W51_RS22200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS22205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS22205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3W51_RS22210	COG1363	Peptidase, m42
D3W51_RS22215	COG3711	transcriptional antiterminator
D3W51_RS22215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3W51_RS22230	COG0243	molybdopterin cofactor binding
D3W51_RS22230	COG3383	formate dehydrogenase (NAD+) activity
D3W51_RS22235	COG3383	formate dehydrogenase (NAD+) activity
D3W51_RS22235	COG0243	molybdopterin cofactor binding
D3W51_RS22240	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS22245	COG2864	formate dehydrogenase
D3W51_RS22255	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D3W51_RS22260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D3W51_RS22265	COG0456	acetyltransferase
D3W51_RS22280	COG1011	Hydrolase
D3W51_RS22285	COG1349	DNA-binding transcription factor activity
D3W51_RS22290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS22295	COG2084	Dehydrogenase
D3W51_RS22300	COG3684	Belongs to the aldolase LacD family
D3W51_RS22305	COG2942	2-epimerase
D3W51_RS22310	COG2017	converts alpha-aldose to the beta-anomer
D3W51_RS22315	COG1501	Belongs to the glycosyl hydrolase 31 family
D3W51_RS22320	COG2211	Major facilitator Superfamily
D3W51_RS22325	COG2211	Major facilitator Superfamily
D3W51_RS22330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D3W51_RS22335	COG2271	Major facilitator Superfamily
D3W51_RS22340	COG1082	Xylose isomerase domain protein TIM barrel
D3W51_RS22345	COG2188	Transcriptional regulator
D3W51_RS22350	COG1217	gtp-binding protein TYPA
D3W51_RS22355	COG0174	glutamine synthetase
D3W51_RS22360	COG3852	Histidine kinase
D3W51_RS22365	COG2204	response regulator
D3W51_RS22375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3W51_RS22390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3W51_RS22390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3W51_RS22400	COG0204	Acyl-transferase
D3W51_RS22405	COG5339	Protein conserved in bacteria
D3W51_RS22410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3W51_RS22415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3W51_RS22420	COG3084	Protein conserved in bacteria
D3W51_RS22425	COG0746	molybdenum cofactor guanylyltransferase activity
D3W51_RS22430	COG1763	Mo-molybdopterin cofactor biosynthetic process
D3W51_RS22460	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
D3W51_RS22465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3W51_RS22470	COG1739	Uncharacterized protein family UPF0029
D3W51_RS22485	COG0183	Belongs to the thiolase family
D3W51_RS22490	COG0543	2 iron, 2 sulfur cluster binding
D3W51_RS22495	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D3W51_RS22500	COG0250	Participates in transcription elongation, termination and antitermination
D3W51_RS22505	COG0084	hydrolase, TatD family'
D3W51_RS22510	COG0805	protein transport
D3W51_RS22515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3W51_RS22520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3W51_RS22530	COG3165	ubiquinone biosynthetic process from chorismate
D3W51_RS22540	COG1322	Protein conserved in bacteria
D3W51_RS22545	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D3W51_RS22550	COG0412	Dienelactone hydrolase
D3W51_RS22560	COG0583	DNA-binding transcription factor activity
D3W51_RS22565	COG0697	spore germination
D3W51_RS22570	COG0561	phosphatase activity
D3W51_RS22575	COG2267	carboxylic ester hydrolase activity
D3W51_RS22580	COG1280	lysine exporter protein (LysE YggA)
D3W51_RS22585	COG1280	lysine exporter protein (LysE YggA)
D3W51_RS22590	COG0514	ATP-dependent DNA helicase (RecQ)
D3W51_RS22595	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
D3W51_RS22600	COG2050	protein possibly involved in aromatic compounds catabolism
D3W51_RS22605	COG2962	Rard protein
D3W51_RS22620	COG0598	Magnesium transport protein CorA
D3W51_RS22625	COG3698	Phosphodiester glycosidase
D3W51_RS22630	COG0210	DNA helicase
D3W51_RS22635	COG1011	Hydrolase
D3W51_RS22645	COG3159	Protein conserved in bacteria
D3W51_RS22655	COG5567	small periplasmic lipoprotein
D3W51_RS22665	COG3072	Adenylate cyclase
D3W51_RS22675	COG1587	Uroporphyrinogen-III synthase
D3W51_RS22680	COG2959	enzyme of heme biosynthesis
D3W51_RS22685	COG3071	HemY protein
D3W51_RS22690	COG3119	arylsulfatase activity
D3W51_RS22720	COG1113	amino acid transport
D3W51_RS22740	COG2244	polysaccharide biosynthetic process
D3W51_RS22745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3W51_RS22750	COG0456	acetyltransferase
D3W51_RS22755	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D3W51_RS22760	COG1088	dTDP-glucose 4,6-dehydratase activity
D3W51_RS22765	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D3W51_RS22770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D3W51_RS22775	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
D3W51_RS22780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3W51_RS22790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D3W51_RS22800	COG3118	belongs to the thioredoxin family
D3W51_RS22815	COG0210	DNA helicase
D3W51_RS22825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3W51_RS22835	COG0583	DNA-binding transcription factor activity
D3W51_RS22840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3W51_RS22850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3W51_RS22855	COG3978	acetolactate synthase activity
D3W51_RS22875	COG0606	chelatase, subunit chli
D3W51_RS22880	COG3085	chromosome segregation
D3W51_RS22920	COG2186	Transcriptional regulator
D3W51_RS22925	COG0477	Major facilitator Superfamily
D3W51_RS22930	COG1609	Transcriptional regulator
D3W51_RS22935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3W51_RS22940	COG1879	ABC-type sugar transport system periplasmic component
D3W51_RS22945	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3W51_RS22950	COG1129	ABC transporter
D3W51_RS22980	COG1522	sequence-specific DNA binding
D3W51_RS22985	COG0716	FMN binding
D3W51_RS23000	COG3312	ion transport
D3W51_RS23050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3W51_RS23055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3W51_RS23060	COG0573	inorganic phosphate transmembrane transporter activity
D3W51_RS23065	COG0581	inorganic phosphate transmembrane transporter activity
D3W51_RS23070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3W51_RS23075	COG0704	Plays a role in the regulation of phosphate uptake
D3W51_RS23080	COG3711	transcriptional antiterminator
D3W51_RS23085	COG1263	PTS System
D3W51_RS23085	COG2190	(PTS) system
D3W51_RS23085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3W51_RS23090	COG2723	6-phospho-beta-galactosidase activity
D3W51_RS23100	COG2382	esterase
D3W51_RS23105	COG0363	glucosamine-6-phosphate deaminase activity
D3W51_RS23110	COG3196	Protein conserved in bacteria
D3W51_RS23120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3W51_RS23125	COG2252	PERMEase
D3W51_RS23130	COG0431	NADPH-dependent FMN reductase
D3W51_RS23135	COG2091	lysine biosynthetic process via aminoadipic acid
D3W51_RS23150	COG0814	amino acid
D3W51_RS23240	COG3385	transposase activity
D3W51_RS23260	COG1285	pathogenesis
D3W51_RS23265	COG2211	Major facilitator Superfamily
D3W51_RS23300	COG3385	transposase activity
D3W51_RS23305	COG3344	reverse transcriptase
D3W51_RS23320	COG2801	Transposase and inactivated derivatives
D3W51_RS23330	COG3344	reverse transcriptase
D3W51_RS23340	COG2207	Transcriptional regulator
D3W51_RS23450	COG1695	Transcriptional regulator
D3W51_RS23485	COG3173	Aminoglycoside phosphotransferase
D3W51_RS23600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3W51_RS23805	COG0243	molybdopterin cofactor binding
D3W51_RS23810	COG0437	4 iron, 4 sulfur cluster binding
D3W51_RS23815	COG3302	dmso reductase anchor subunit
D3W51_RS23820	COG3381	protein complex oligomerization
D3W51_RS23830	COG3039	Transposase
D3W51_RS23955	COG3118	belongs to the thioredoxin family
D3W51_RS23955	COG0457	Tetratricopeptide repeat
D3W51_RS23975	COG3344	reverse transcriptase
D3W51_RS23985	COG1215	transferase activity, transferring glycosyl groups
D3W51_RS24005	COG2199	diguanylate cyclase activity
D3W51_RS24010	COG2200	EAL domain
D3W51_RS24055	COG2826	transposase and inactivated derivatives, IS30 family
D3W51_RS24115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D3W51_RS24125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3W51_RS24250	COG3121	Chaperone
D3W51_RS24255	COG3188	usher protein
D3W51_RS24340	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D3W51_RS24350	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3W51_RS24390	COG3941	tape measure
D3W51_RS24480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3W51_RS24485	COG1475	DNA binding
D3W51_RS24490	COG1475	DNA binding
D3W51_RS24495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3W51_RS24580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D3W51_RS24650	COG0328	RNA-DNA hybrid ribonuclease activity
D3W51_RS24675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3W51_RS24700	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis