locus-tag	class	description
WM48_RS00010	COG0460	homoserine dehydrogenase
WM48_RS00010	COG0527	aspartate kinase activity
WM48_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WM48_RS00040	COG1115	amino acid carrier protein
WM48_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
WM48_RS00060	COG1584	GPR1 FUN34 yaaH family protein
WM48_RS00065	COG4735	regulation of single-species biofilm formation
WM48_RS00095	COG3119	arylsulfatase activity
WM48_RS00110	COG0583	DNA-binding transcription factor activity
WM48_RS00125	COG0196	riboflavin kinase activity
WM48_RS00140	COG1047	Peptidyl-prolyl cis-trans
WM48_RS00170	COG0505	Belongs to the CarA family
WM48_RS00175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WM48_RS00230	COG0644	oxidoreductase
WM48_RS00235	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
WM48_RS00240	COG2271	Major facilitator Superfamily
WM48_RS00255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WM48_RS00290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WM48_RS00300	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WM48_RS00305	COG0564	pseudouridine synthase activity
WM48_RS00315	COG0417	DNA replication proofreading
WM48_RS00320	COG0235	Class ii aldolase
WM48_RS00335	COG4977	sequence-specific DNA binding
WM48_RS00350	COG0586	Pfam SNARE associated Golgi protein
WM48_RS00360	COG1178	ABC-type Fe3 transport system permease component
WM48_RS00365	COG4143	(ABC) transporter
WM48_RS00390	COG0473	3-isopropylmalate dehydrogenase activity
WM48_RS00405	COG0583	DNA-binding transcription factor activity
WM48_RS00410	COG0028	Belongs to the TPP enzyme family
WM48_RS00415	COG0440	acetolactate synthase activity
WM48_RS00425	COG1609	Transcriptional regulator
WM48_RS00440	COG3116	cell division
WM48_RS00445	COG0768	penicillin binding
WM48_RS00450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WM48_RS00455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WM48_RS00470	COG0772	Belongs to the SEDS family
WM48_RS00485	COG1181	Belongs to the D-alanine--D-alanine ligase family
WM48_RS00490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WM48_RS00495	COG0849	cell division
WM48_RS00500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WM48_RS00520	COG0494	nUDIX hydrolase
WM48_RS00535	COG0237	dephospho-CoA kinase activity
WM48_RS00545	COG1459	type II secretion system
WM48_RS00550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WM48_RS00555	COG4969	Belongs to the N-Me-Phe pilin family
WM48_RS00565	COG0157	Belongs to the NadC ModD family
WM48_RS00570	COG3023	N-Acetylmuramoyl-L-alanine amidase
WM48_RS00575	COG3725	Membrane protein required for beta-lactamase induction
WM48_RS00580	COG1113	amino acid transport
WM48_RS00585	COG3157	Type VI secretion system effector, Hcp
WM48_RS00615	COG2186	Transcriptional regulator
WM48_RS00620	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WM48_RS00625	COG0508	dehydrogenase complex catalyzes the overall conversion of
WM48_RS00630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WM48_RS00635	COG3064	Membrane
WM48_RS00640	COG1049	propionate catabolic process, 2-methylcitrate cycle
WM48_RS00665	COG2132	Multicopper oxidase
WM48_RS00675	COG4993	Dehydrogenase
WM48_RS00680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WM48_RS00685	COG0288	reversible hydration of carbon dioxide
WM48_RS00690	COG1131	(ABC) transporter
WM48_RS00695	COG0842	Transport permease protein
WM48_RS00700	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS00705	COG0726	polysaccharide deacetylase
WM48_RS00715	COG5464	transposase or invertase
WM48_RS00735	COG3539	Fimbrial protein
WM48_RS00740	COG3539	Fimbrial protein
WM48_RS00745	COG3539	Fimbrial protein
WM48_RS00750	COG3539	Fimbrial protein
WM48_RS00755	COG3188	usher protein
WM48_RS00760	COG3121	Chaperone
WM48_RS00765	COG3539	Fimbrial protein
WM48_RS00770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WM48_RS00775	COG0617	tRNA 3'-terminal CCA addition
WM48_RS00780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WM48_RS00785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WM48_RS00795	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
WM48_RS00800	COG1643	Atp-dependent helicase
WM48_RS00805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WM48_RS00810	COG4774	siderophore transport
WM48_RS00815	COG1120	ATPase activity
WM48_RS00820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WM48_RS00825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS00845	COG2860	membrane
WM48_RS00850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WM48_RS00865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WM48_RS00870	COG3835	regulator
WM48_RS00890	COG0024	Methionine aminopeptidase
WM48_RS00915	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WM48_RS00920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WM48_RS00925	COG0575	Belongs to the CDS family
WM48_RS00930	COG0750	zinc metalloprotease
WM48_RS00940	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
WM48_RS00945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WM48_RS00970	COG0587	DNA-directed DNA polymerase activity
WM48_RS00980	COG1982	Orn Lys Arg decarboxylase major
WM48_RS00985	COG0346	lactoylglutathione lyase activity
WM48_RS00990	COG0037	tRNA processing
WM48_RS00995	COG4568	rho-dependent transcription termination
WM48_RS01005	COG4681	YaeQ
WM48_RS01010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WM48_RS01015	COG3015	lipoprotein NlpE involved in copper resistance
WM48_RS01020	COG0791	NLP P60 protein
WM48_RS01030	COG1720	tRNA m6t6A37 methyltransferase activity
WM48_RS01040	COG1464	Belongs to the NlpA lipoprotein family
WM48_RS01045	COG2011	ABC-type metal ion transport system permease component
WM48_RS01055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WM48_RS01090	COG0656	L-ascorbic acid biosynthetic process
WM48_RS01095	COG0583	DNA-binding transcription factor activity
WM48_RS01105	COG2226	methyltransferase
WM48_RS01110	COG1388	LysM domain
WM48_RS01110	COG0741	lytic transglycosylase activity
WM48_RS01120	COG2226	methyltransferase
WM48_RS01130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WM48_RS01230	COG3501	Rhs element vgr protein
WM48_RS01250	COG5433	transposase activity
WM48_RS01270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WM48_RS01280	COG1960	acyl-CoA dehydrogenase activity
WM48_RS01290	COG0121	glutamine amidotransferase
WM48_RS01295	COG3034	peptidoglycan biosynthetic process
WM48_RS01300	COG0791	NLP P60 protein
WM48_RS01305	COG1943	Transposase
WM48_RS01325	COG2161	toxin-antitoxin pair type II binding
WM48_RS01335	COG0454	-acetyltransferase
WM48_RS01340	COG1690	Belongs to the RtcB family
WM48_RS01345	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WM48_RS01350	COG2195	Cleaves the N-terminal amino acid of tripeptides
WM48_RS01370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WM48_RS01410	COG4983	Phage plasmid primase, P4 family domain protein
WM48_RS01450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WM48_RS01455	COG2801	Transposase and inactivated derivatives
WM48_RS01515	COG3539	Fimbrial protein
WM48_RS01560	COG2819	hydrolase of the alpha beta superfamily
WM48_RS01565	COG2382	esterase
WM48_RS01585	COG3385	transposase activity
WM48_RS01605	COG4771	TonB-dependent receptor
WM48_RS01615	COG0523	cobalamin synthesis protein
WM48_RS01620	COG4372	Transposase
WM48_RS01640	COG3436	PFAM IS66 Orf2 family protein
WM48_RS01650	COG0583	DNA-binding transcription factor activity
WM48_RS01655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WM48_RS01670	COG0531	amino acid
WM48_RS01690	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS01705	COG2003	Belongs to the UPF0758 family
WM48_RS01750	COG0582	viral genome integration into host DNA
WM48_RS01785	COG3477	response to acidic pH
WM48_RS01790	COG0727	PFAM Uncharacterised protein family (UPF0153)
WM48_RS01805	COG3188	usher protein
WM48_RS01840	COG1902	pentaerythritol trinitrate reductase activity
WM48_RS01845	COG1073	alpha beta
WM48_RS01850	COG0583	DNA-binding transcription factor activity
WM48_RS01860	COG0667	Aldo Keto reductase
WM48_RS01865	COG0656	L-ascorbic acid biosynthetic process
WM48_RS01870	COG4932	domain protein
WM48_RS01870	COG2373	Large extracellular alpha-helical protein
WM48_RS01870	COG1388	LysM domain
WM48_RS01875	COG2207	Transcriptional regulator
WM48_RS01875	COG3708	Transcriptional regulator
WM48_RS01880	COG0656	L-ascorbic acid biosynthetic process
WM48_RS01885	COG3059	membrane
WM48_RS01895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WM48_RS01900	COG2207	Transcriptional regulator
WM48_RS01905	COG0247	lactate metabolic process
WM48_RS01910	COG1139	Iron-sulfur cluster binding protein
WM48_RS01915	COG1556	Lactate utilization protein
WM48_RS01930	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS01940	COG2771	luxR family
WM48_RS01940	COG2200	EAL domain
WM48_RS01945	COG0582	viral genome integration into host DNA
WM48_RS01970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WM48_RS01980	COG2771	luxR family
WM48_RS01980	COG2200	EAL domain
WM48_RS01985	COG0583	DNA-binding transcription factor activity
WM48_RS01995	COG0666	response to abiotic stimulus
WM48_RS02005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM48_RS02010	COG1304	FMN binding
WM48_RS02020	COG0549	Belongs to the carbamate kinase family
WM48_RS02025	COG0402	S-adenosylhomocysteine deaminase activity
WM48_RS02030	COG1064	alcohol dehydrogenase
WM48_RS02040	COG1280	lysine exporter protein (LysE YggA)
WM48_RS02050	COG3829	transcription factor binding
WM48_RS02055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WM48_RS02060	COG0372	Belongs to the citrate synthase family
WM48_RS02065	COG2079	MmgE PrpD family protein
WM48_RS02070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WM48_RS02075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WM48_RS02080	COG0402	S-adenosylhomocysteine deaminase activity
WM48_RS02085	COG2801	Transposase and inactivated derivatives
WM48_RS02100	COG0110	maltose O-acetyltransferase activity
WM48_RS02105	COG2223	nitrite transmembrane transporter activity
WM48_RS02115	COG1609	Transcriptional regulator
WM48_RS02120	COG3122	Protein conserved in bacteria
WM48_RS02150	COG1215	transferase activity, transferring glycosyl groups
WM48_RS02155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
WM48_RS02160	COG4521	taurine ABC transporter
WM48_RS02170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WM48_RS02175	COG2175	clavaminate synthase activity
WM48_RS02180	COG0113	porphobilinogen synthase activity
WM48_RS02185	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS02190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WM48_RS02195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WM48_RS02205	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
WM48_RS02225	COG1181	Belongs to the D-alanine--D-alanine ligase family
WM48_RS02235	COG1785	Belongs to the alkaline phosphatase family
WM48_RS02245	COG3706	GGDEF domain
WM48_RS02250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WM48_RS02275	COG4126	flavin adenine dinucleotide binding
WM48_RS02295	COG1940	carbohydrate kinase activity
WM48_RS02300	COG2814	Major facilitator Superfamily
WM48_RS02305	COG0419	ATPase involved in DNA repair
WM48_RS02310	COG0420	3'-5' exonuclease activity
WM48_RS02315	COG0745	RESPONSE REGULATOR receiver
WM48_RS02320	COG5002	protein histidine kinase activity
WM48_RS02325	COG1114	Component of the transport system for branched-chain amino acids
WM48_RS02330	COG1113	amino acid transport
WM48_RS02335	COG0366	Alpha amylase catalytic
WM48_RS02355	COG1862	Preprotein translocase
WM48_RS02360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WM48_RS02365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WM48_RS02370	COG1403	HNH endonuclease
WM48_RS02375	COG3248	Nucleoside-binding outer membrane protein
WM48_RS02380	COG4238	major outer membrane lipoprotein
WM48_RS02390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WM48_RS02390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WM48_RS02405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WM48_RS02410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WM48_RS02415	COG0667	Aldo Keto reductase
WM48_RS02425	COG0142	geranyltranstransferase activity
WM48_RS02440	COG0693	protein deglycase activity
WM48_RS02445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WM48_RS02455	COG2814	Major facilitator Superfamily
WM48_RS02465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WM48_RS02470	COG1845	cytochrome c oxidase, subunit III
WM48_RS02475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WM48_RS02480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WM48_RS02485	COG2223	nitrite transmembrane transporter activity
WM48_RS02490	COG3056	Lipoprotein
WM48_RS02495	COG0271	Belongs to the BolA IbaG family
WM48_RS02520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WM48_RS02525	COG0776	regulation of translation
WM48_RS02530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WM48_RS02535	COG1555	photosystem II stabilization
WM48_RS02540	COG0824	Thioesterase
WM48_RS02550	COG4533	DNA binding
WM48_RS02560	COG1522	sequence-specific DNA binding
WM48_RS02565	COG1132	(ABC) transporter
WM48_RS02570	COG1132	(ABC) transporter
WM48_RS02575	COG0347	Belongs to the P(II) protein family
WM48_RS02580	COG0004	ammonium transporteR
WM48_RS02585	COG1946	Acyl-CoA thioesterase
WM48_RS02590	COG3126	Type III secretion system lipoprotein chaperone (YscW)
WM48_RS02595	COG3695	enzyme binding
WM48_RS02605	COG5507	3-demethylubiquinone-9 3-methyltransferase
WM48_RS02610	COG4943	cyclic-guanylate-specific phosphodiesterase activity
WM48_RS02620	COG0110	maltose O-acetyltransferase activity
WM48_RS02635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM48_RS02640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS02645	COG1309	transcriptional regulator
WM48_RS02650	COG3264	Mechanosensitive ion channel
WM48_RS02650	COG1196	nuclear chromosome segregation
WM48_RS02665	COG3923	Primosomal replication protein n
WM48_RS02670	COG2832	Protein of unknown function (DUF454)
WM48_RS02680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WM48_RS02715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS02720	COG4651	solute:proton antiporter activity
WM48_RS02720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WM48_RS02725	COG2223	nitrite transmembrane transporter activity
WM48_RS02730	COG0737	Belongs to the 5'-nucleotidase family
WM48_RS02745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WM48_RS02750	COG3735	TraB family
WM48_RS02755	COG3549	Plasmid maintenance system killer
WM48_RS02760	COG3093	addiction module antidote protein HigA
WM48_RS02765	COG2217	Heavy metal translocating P-type atpase
WM48_RS02775	COG0531	amino acid
WM48_RS02780	COG0789	Transcriptional regulator
WM48_RS02790	COG1585	Membrane protein implicated in regulation of membrane protease activity
WM48_RS02795	COG0330	HflC and HflK could
WM48_RS02800	COG4619	ABC transporter
WM48_RS02805	COG0390	transport system, permease component
WM48_RS02810	COG3118	belongs to the thioredoxin family
WM48_RS02815	COG0300	oxidoreductase activity
WM48_RS02820	COG2755	lipolytic protein G-D-S-L family
WM48_RS02825	COG4181	ATPase activity
WM48_RS02830	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WM48_RS02850	COG1414	Transcriptional regulator
WM48_RS02855	COG3960	tartronate-semialdehyde synthase activity
WM48_RS02860	COG3622	Belongs to the hyi family
WM48_RS02865	COG2084	Dehydrogenase
WM48_RS02870	COG1953	Uracil, thiamine, allantoin
WM48_RS02880	COG2233	PERMEase
WM48_RS02885	COG1929	Belongs to the glycerate kinase type-1 family
WM48_RS02890	COG3257	ureidoglycine aminohydrolase activity
WM48_RS02895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WM48_RS02900	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WM48_RS02905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM48_RS02910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM48_RS02920	COG0549	Belongs to the carbamate kinase family
WM48_RS02925	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WM48_RS02930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WM48_RS02945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WM48_RS02955	COG1988	membrane-bound metal-dependent
WM48_RS02960	COG2501	S4 domain
WM48_RS02980	COG0582	viral genome integration into host DNA
WM48_RS02985	COG0582	viral genome integration into host DNA
WM48_RS02995	COG0500	methyltransferase
WM48_RS03000	COG4571	Outer membrane protease
WM48_RS03010	COG4783	chaperone-mediated protein folding
WM48_RS03015	COG1215	transferase activity, transferring glycosyl groups
WM48_RS03020	COG5002	protein histidine kinase activity
WM48_RS03025	COG0745	RESPONSE REGULATOR receiver
WM48_RS03030	COG1538	Outer membrane efflux protein
WM48_RS03035	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS03040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS03045	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM48_RS03050	COG1113	amino acid transport
WM48_RS03055	COG0668	transmembrane transport
WM48_RS03060	COG0778	Nitroreductase
WM48_RS03065	COG2315	Protein conserved in bacteria
WM48_RS03090	COG2977	Belongs to the P-Pant transferase superfamily
WM48_RS03095	COG4771	TonB-dependent receptor
WM48_RS03100	COG2382	esterase
WM48_RS03105	COG3251	PFAM MbtH domain protein
WM48_RS03110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WM48_RS03110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
WM48_RS03115	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
WM48_RS03120	COG1120	ATPase activity
WM48_RS03125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS03140	COG4592	Periplasmic binding protein
WM48_RS03145	COG1169	isochorismate synthase
WM48_RS03150	COG1021	2,3-dihydroxybenzoate-AMP ligase
WM48_RS03155	COG1535	isochorismatase
WM48_RS03155	COG3433	isochorismatase activity
WM48_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS03165	COG2050	protein possibly involved in aromatic compounds catabolism
WM48_RS03170	COG1966	Carbon starvation protein
WM48_RS03175	COG2879	small protein
WM48_RS03180	COG0371	Dehydrogenase
WM48_RS03185	COG0436	Aminotransferase
WM48_RS03190	COG1475	DNA binding
WM48_RS03195	COG3969	phosphoadenosine phosphosulfate
WM48_RS03200	COG0583	DNA-binding transcription factor activity
WM48_RS03205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WM48_RS03210	COG0450	alkyl hydroperoxide reductase
WM48_RS03215	COG3634	alkyl hydroperoxide reductase activity
WM48_RS03220	COG0589	response to stress
WM48_RS03225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WM48_RS03230	COG3719	Belongs to the RNase T2 family
WM48_RS03235	COG0471	metal ion transport
WM48_RS03250	COG3051	citrate lyase alpha subunit
WM48_RS03255	COG2301	Belongs to the HpcH HpaI aldolase family
WM48_RS03265	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
WM48_RS03270	COG3290	protein histidine kinase activity
WM48_RS03275	COG4565	transcriptional regulatory protein
WM48_RS03280	COG3069	C4-dicarboxylate transmembrane transporter activity
WM48_RS03300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WM48_RS03305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WM48_RS03315	COG0583	DNA-binding transcription factor activity
WM48_RS03335	COG1686	Belongs to the peptidase S11 family
WM48_RS03340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WM48_RS03345	COG0772	Belongs to the SEDS family
WM48_RS03350	COG0768	penicillin binding
WM48_RS03360	COG0799	negative regulation of ribosome biogenesis
WM48_RS03365	COG0406	alpha-ribazole phosphatase activity
WM48_RS03375	COG1466	dna polymerase III delta subunit
WM48_RS03390	COG2888	peptidyl-tyrosine sulfation
WM48_RS03400	COG1126	abc transporter atp-binding protein
WM48_RS03405	COG0765	amino acid transport
WM48_RS03410	COG0765	amino acid transport
WM48_RS03415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS03425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WM48_RS03430	COG4535	Mg2 and Co2 transporter CorC
WM48_RS03440	COG1702	phosphate starvation-inducible protein PhoH
WM48_RS03450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WM48_RS03490	COG0367	asparagine synthase
WM48_RS03495	COG0647	UMP catabolic process
WM48_RS03500	COG1846	Transcriptional regulator
WM48_RS03500	COG1940	carbohydrate kinase activity
WM48_RS03505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WM48_RS03515	COG1263	PTS System
WM48_RS03515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS03515	COG2190	(PTS) system
WM48_RS03535	COG0861	Integral membrane protein TerC family
WM48_RS03540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WM48_RS03545	COG1454	alcohol dehydrogenase
WM48_RS03550	COG3395	kinase activity
WM48_RS03555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WM48_RS03560	COG1349	DNA-binding transcription factor activity
WM48_RS03580	COG0735	belongs to the Fur family
WM48_RS03595	COG0716	FMN binding
WM48_RS03605	COG0596	Alpha beta hydrolase
WM48_RS03610	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
WM48_RS03615	COG0033	Phosphoglucomutase
WM48_RS03620	COG0531	amino acid
WM48_RS03625	COG1982	Orn Lys Arg decarboxylase major
WM48_RS03635	COG0745	RESPONSE REGULATOR receiver
WM48_RS03640	COG2205	protein histidine kinase activity
WM48_RS03670	COG3272	Protein of unknown function (DUF1722)
WM48_RS03675	COG0415	Belongs to the DNA photolyase family
WM48_RS03685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WM48_RS03690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WM48_RS03695	COG1984	allophanate hydrolase subunit 2
WM48_RS03710	COG3180	Ammonia monooxygenase
WM48_RS03715	COG3539	Fimbrial protein
WM48_RS03720	COG0372	Belongs to the citrate synthase family
WM48_RS03730	COG2009	succinate dehydrogenase
WM48_RS03735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WM48_RS03740	COG1053	succinate dehydrogenase
WM48_RS03745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WM48_RS03755	COG0567	Dehydrogenase, E1 component
WM48_RS03760	COG0508	dehydrogenase complex catalyzes the overall conversion of
WM48_RS03770	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM48_RS03785	COG1271	oxidase subunit
WM48_RS03790	COG1294	oxidase, subunit
WM48_RS03795	COG4890	Cyd operon protein YbgT
WM48_RS03800	COG3790	cyd operon protein YbgE
WM48_RS03805	COG0824	Thioesterase
WM48_RS03810	COG0811	peptide transport
WM48_RS03815	COG0848	biopolymer transport protein
WM48_RS03820	COG3064	Membrane
WM48_RS03830	COG2885	chlorophyll binding
WM48_RS03835	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
WM48_RS03880	COG3201	nicotinamide mononucleotide transporter
WM48_RS03885	COG1230	cation diffusion facilitator family transporter
WM48_RS03900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WM48_RS03910	COG2017	converts alpha-aldose to the beta-anomer
WM48_RS03920	COG1085	galactose-1-phosphate uridylyltransferase
WM48_RS03925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WM48_RS03930	COG1119	ATPase activity
WM48_RS03940	COG2005	Transcriptional regulator
WM48_RS03940	COG3585	molybdate ion transport
WM48_RS03950	COG0725	ABC transporter, periplasmic molybdate-binding protein
WM48_RS03955	COG4149	molybdate abc transporter
WM48_RS03965	COG0561	phosphatase activity
WM48_RS03975	COG0583	DNA-binding transcription factor activity
WM48_RS03980	COG2828	Protein conserved in bacteria
WM48_RS03985	COG0471	metal ion transport
WM48_RS03990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WM48_RS03995	COG4677	pectinesterase activity
WM48_RS04000	COG1881	PFAM PEBP family protein
WM48_RS04010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WM48_RS04025	COG2226	methyltransferase
WM48_RS04030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WM48_RS04040	COG0391	Required for morphogenesis under gluconeogenic growth conditions
WM48_RS04050	COG0521	Mo-molybdopterin cofactor biosynthetic process
WM48_RS04060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WM48_RS04065	COG0314	molybdopterin synthase activity
WM48_RS04070	COG0670	Belongs to the BI1 family
WM48_RS04075	COG0670	Belongs to the BI1 family
WM48_RS04080	COG0392	lysyltransferase activity
WM48_RS04085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM48_RS04090	COG3568	Endonuclease Exonuclease Phosphatase
WM48_RS04100	COG0842	Transport permease protein
WM48_RS04105	COG0842	Transport permease protein
WM48_RS04110	COG1131	(ABC) transporter
WM48_RS04120	COG1309	transcriptional regulator
WM48_RS04125	COG0513	Belongs to the DEAD box helicase family
WM48_RS04135	COG1199	ATP-dependent helicase activity
WM48_RS04140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WM48_RS04145	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WM48_RS04155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WM48_RS04180	COG0668	transmembrane transport
WM48_RS04185	COG1126	abc transporter atp-binding protein
WM48_RS04190	COG0765	amino acid transport
WM48_RS04195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS04210	COG5006	permease, DMT superfamily
WM48_RS04215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WM48_RS04220	COG2194	sulfuric ester hydrolase activity
WM48_RS04230	COG1321	iron dependent repressor
WM48_RS04235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WM48_RS04240	COG1376	ErfK ybiS ycfS ynhG family protein
WM48_RS04245	COG0488	(ABC) transporter
WM48_RS04250	COG0561	phosphatase activity
WM48_RS04255	COG1882	Formate acetyltransferase
WM48_RS04260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM48_RS04265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WM48_RS04270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WM48_RS04275	COG0303	'Molybdopterin
WM48_RS04280	COG1446	asparaginase
WM48_RS04305	COG2200	EAL domain
WM48_RS04310	COG2199	diguanylate cyclase activity
WM48_RS04325	COG2133	pyrroloquinoline quinone binding
WM48_RS04330	COG0625	glutathione transferase activity
WM48_RS04335	COG1686	Belongs to the peptidase S11 family
WM48_RS04340	COG1349	DNA-binding transcription factor activity
WM48_RS04345	COG0671	phosphoesterase, PA-phosphatase related
WM48_RS04350	COG2814	Major facilitator Superfamily
WM48_RS04360	COG0561	phosphatase activity
WM48_RS04365	COG0738	Major facilitator superfamily
WM48_RS04370	COG3226	Transcriptional regulator
WM48_RS04385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WM48_RS04395	COG0778	Nitroreductase
WM48_RS04415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WM48_RS04420	COG3842	ATPase activity
WM48_RS04425	COG1176	ABC-type spermidine putrescine transport system, permease component I
WM48_RS04430	COG1177	transmembrane transport
WM48_RS04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS04450	COG4160	amino acid transport
WM48_RS04455	COG4215	(ABC) transporter
WM48_RS04460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS04465	COG1126	abc transporter atp-binding protein
WM48_RS04480	COG3023	N-Acetylmuramoyl-L-alanine amidase
WM48_RS04485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WM48_RS04490	COG0702	epimerase
WM48_RS04495	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
WM48_RS04500	COG0028	Belongs to the TPP enzyme family
WM48_RS04505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WM48_RS04515	COG2431	L-lysine efflux transmembrane transporter activity
WM48_RS04530	COG3593	DNA synthesis involved in DNA repair
WM48_RS04535	COG2990	Protein conserved in bacteria
WM48_RS04540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS04550	COG1278	Cold shock
WM48_RS04610	COG0740	serine-type endopeptidase activity
WM48_RS04630	COG0542	response to heat
WM48_RS04650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WM48_RS04655	COG4988	ABC transporter
WM48_RS04660	COG0492	ferredoxin-NADP+ reductase activity
WM48_RS04665	COG1522	sequence-specific DNA binding
WM48_RS04670	COG1178	ABC-type Fe3 transport system permease component
WM48_RS04670	COG1674	ftsk spoiiie
WM48_RS04680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WM48_RS04690	COG0243	molybdopterin cofactor binding
WM48_RS04695	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS04700	COG3302	dmso reductase anchor subunit
WM48_RS04705	COG1335	isochorismatase
WM48_RS04715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM48_RS04720	COG1882	Formate acetyltransferase
WM48_RS04725	COG2116	formate transmembrane transporter activity
WM48_RS04730	COG1944	ATP diphosphatase activity
WM48_RS04735	COG2323	membrane
WM48_RS04750	COG0501	Belongs to the peptidase M48B family
WM48_RS04760	COG0539	negative regulation of cytoplasmic translation
WM48_RS04770	COG0658	competence protein
WM48_RS04770	COG2333	competence protein COMEC
WM48_RS04785	COG3214	Protein conserved in bacteria
WM48_RS04800	COG3173	Aminoglycoside phosphotransferase
WM48_RS04805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WM48_RS04810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WM48_RS04820	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
WM48_RS04830	COG2989	Protein conserved in bacteria
WM48_RS04835	COG3108	Peptidase M15
WM48_RS04840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WM48_RS04845	COG1448	Aminotransferase
WM48_RS04870	COG0308	aminopeptidase N
WM48_RS04880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WM48_RS04890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WM48_RS04895	COG0431	NADPH-dependent FMN reductase
WM48_RS04910	COG0633	Ferredoxin
WM48_RS04910	COG3217	Mosc domain protein beta barrel domain protein
WM48_RS04920	COG0488	(ABC) transporter
WM48_RS04925	COG2995	paraquat-inducible protein a
WM48_RS04930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WM48_RS04930	COG3008	intermembrane lipid transfer
WM48_RS04935	COG3009	Protein conserved in bacteria
WM48_RS04940	COG3130	regulation of translation
WM48_RS04950	COG1067	ATP-dependent peptidase activity
WM48_RS04960	COG2885	chlorophyll binding
WM48_RS04960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WM48_RS04975	COG3070	regulator of competence-specific genes
WM48_RS04980	COG1289	transmembrane transporter activity
WM48_RS04985	COG3304	Inner membrane component domain
WM48_RS04990	COG0210	DNA helicase
WM48_RS05010	COG1832	CoA-binding protein
WM48_RS05025	COG1254	Belongs to the acylphosphatase family
WM48_RS05030	COG2920	part of a sulfur-relay system
WM48_RS05035	COG0670	Belongs to the BI1 family
WM48_RS05045	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WM48_RS05050	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WM48_RS05055	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
WM48_RS05060	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WM48_RS05065	COG1999	signal sequence binding
WM48_RS05070	COG1773	rubredoxin
WM48_RS05075	COG1271	oxidase subunit
WM48_RS05080	COG1294	oxidase, subunit
WM48_RS05095	COG1278	Cold shock
WM48_RS05100	COG1278	Cold shock
WM48_RS05115	COG0348	domain, Protein
WM48_RS05120	COG0784	Response regulator, receiver
WM48_RS05120	COG2198	Histidine kinase
WM48_RS05120	COG2205	protein histidine kinase activity
WM48_RS05125	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS05130	COG0745	RESPONSE REGULATOR receiver
WM48_RS05135	COG3005	denitrification pathway
WM48_RS05140	COG0243	molybdopterin cofactor binding
WM48_RS05180	COG3729	General stress protein
WM48_RS05185	COG2233	PERMEase
WM48_RS05220	COG1309	transcriptional regulator
WM48_RS05225	COG0506	proline dehydrogenase activity
WM48_RS05225	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WM48_RS05225	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WM48_RS05235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WM48_RS05255	COG1702	phosphate starvation-inducible protein PhoH
WM48_RS05260	COG3658	cytochrome
WM48_RS05265	COG1215	transferase activity, transferring glycosyl groups
WM48_RS05270	COG0726	polysaccharide deacetylase
WM48_RS05270	COG1649	PFAM Uncharacterised BCR, COG1649
WM48_RS05275	COG0457	Tetratricopeptide repeat
WM48_RS05280	COG3706	GGDEF domain
WM48_RS05305	COG3381	protein complex oligomerization
WM48_RS05315	COG1462	curli production assembly transport component CsgG
WM48_RS05330	COG2197	response regulator
WM48_RS05360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WM48_RS05365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM48_RS05390	COG2943	transferase activity, transferring hexosyl groups
WM48_RS05395	COG5645	(Lipo)protein
WM48_RS05415	COG1560	Kdo2-lipid A biosynthetic process
WM48_RS05425	COG2353	YceI-like domain
WM48_RS05430	COG3038	cytochrome b561
WM48_RS05465	COG2999	glutathione oxidoreductase activity
WM48_RS05475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM48_RS05485	COG0673	inositol 2-dehydrogenase activity
WM48_RS05490	COG0728	peptidoglycan biosynthetic process
WM48_RS05495	COG3418	PFAM FlgN family protein
WM48_RS05500	COG2747	anti-sigma28 factor FlgM
WM48_RS05505	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
WM48_RS05510	COG1815	bacterial-type flagellum-dependent cell motility
WM48_RS05515	COG1558	bacterial-type flagellum-dependent cell motility
WM48_RS05520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WM48_RS05525	COG1749	Flagellar hook protein flgE
WM48_RS05530	COG4787	bacterial-type flagellum-dependent cell motility
WM48_RS05535	COG4786	Flagellar basal body rod
WM48_RS05550	COG1705	Flagellar rod assembly protein muramidase FlgJ
WM48_RS05550	COG3951	Flagellar rod assembly protein muramidase FlgJ
WM48_RS05555	COG1256	bacterial-type flagellum assembly
WM48_RS05560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WM48_RS05565	COG1530	ribonuclease E activity
WM48_RS05575	COG0564	pseudouridine synthase activity
WM48_RS05580	COG0424	maF-like protein
WM48_RS05585	COG1399	metal-binding, possibly nucleic acid-binding protein
WM48_RS05605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WM48_RS05610	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS05620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WM48_RS05625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WM48_RS05630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WM48_RS05640	COG0470	DNA polymerase III
WM48_RS05645	COG0084	hydrolase, TatD family'
WM48_RS05650	COG1263	PTS System
WM48_RS05650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS05660	COG0537	adenosine 5'-monophosphoramidase activity
WM48_RS05665	COG5633	Lipoprotein
WM48_RS05670	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
WM48_RS05690	COG1252	NADH dehydrogenase
WM48_RS05695	COG3134	Outer membrane lipoprotein
WM48_RS05700	COG1309	transcriptional regulator
WM48_RS05710	COG1376	ErfK ybiS ycfS ynhG family protein
WM48_RS05710	COG1388	LysM domain
WM48_RS05715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WM48_RS05725	COG4591	ABC-type transport system involved in lipoprotein release permease component
WM48_RS05735	COG4591	ABC-type transport system involved in lipoprotein release permease component
WM48_RS05745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WM48_RS05750	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WM48_RS05760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WM48_RS05765	COG1177	transmembrane transport
WM48_RS05775	COG3842	ATPase activity
WM48_RS05790	COG2850	peptidyl-arginine hydroxylation
WM48_RS05795	COG2205	protein histidine kinase activity
WM48_RS05805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WM48_RS05825	COG1187	pseudouridine synthase activity
WM48_RS05830	COG0538	isocitrate dehydrogenase activity
WM48_RS05835	COG0582	viral genome integration into host DNA
WM48_RS05980	COG3772	lysozyme
WM48_RS06025	COG4220	transposase activity
WM48_RS06045	COG1030	water channel activity
WM48_RS06095	COG1196	nuclear chromosome segregation
WM48_RS06145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WM48_RS06150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WM48_RS06155	COG1121	(ABC) transporter
WM48_RS06175	COG0456	acetyltransferase
WM48_RS06185	COG5562	phage envelope protein
WM48_RS06190	COG0789	Transcriptional regulator
WM48_RS06195	COG2200	EAL domain
WM48_RS06220	COG2200	EAL domain
WM48_RS06270	COG2894	cell division
WM48_RS06295	COG0179	Fumarylacetoacetate (FAA) hydrolase
WM48_RS06310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WM48_RS06315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WM48_RS06335	COG2719	SpoVR family
WM48_RS06345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WM48_RS06355	COG1619	proteins homologs of microcin C7 resistance protein MccF
WM48_RS06365	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
WM48_RS06380	COG0157	Belongs to the NadC ModD family
WM48_RS06385	COG0500	methyltransferase
WM48_RS06390	COG1120	ATPase activity
WM48_RS06395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS06400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WM48_RS06410	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
WM48_RS06410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS06410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM48_RS06415	COG1461	Dihydroxyacetone kinase
WM48_RS06420	COG2376	Dihydroxyacetone kinase
WM48_RS06425	COG3284	Transcriptional regulator
WM48_RS06435	COG0012	GTP binding
WM48_RS06450	COG0659	secondary active sulfate transmembrane transporter activity
WM48_RS06455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WM48_RS06480	COG2890	protein-(glutamine-N5) methyltransferase activity
WM48_RS06485	COG3094	Invasion gene expression up-regulator, SirB
WM48_RS06490	COG2912	Transglutaminase-like superfamily
WM48_RS06505	COG0387	Pfam Sodium calcium exchanger
WM48_RS06510	COG4572	Cation transport regulator
WM48_RS06515	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
WM48_RS06520	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WM48_RS06525	COG4932	domain protein
WM48_RS06530	COG2197	response regulator
WM48_RS06535	COG3850	Histidine kinase
WM48_RS06545	COG2223	nitrite transmembrane transporter activity
WM48_RS06550	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WM48_RS06555	COG1140	nitrate reductase beta subunit
WM48_RS06560	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WM48_RS06565	COG2181	nitrate reductase activity
WM48_RS06590	COG0788	formyltetrahydrofolate deformylase activity
WM48_RS06600	COG1752	Esterase of the alpha-beta hydrolase superfamily
WM48_RS06605	COG0745	RESPONSE REGULATOR receiver
WM48_RS06610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WM48_RS06620	COG1435	thymidine kinase activity
WM48_RS06625	COG3385	transposase activity
WM48_RS06630	COG1454	alcohol dehydrogenase
WM48_RS06630	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS06635	COG2095	MarC family integral membrane protein
WM48_RS06645	COG4166	transmembrane transport
WM48_RS06650	COG0601	transmembrane transport
WM48_RS06655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WM48_RS06660	COG0444	Belongs to the ABC transporter superfamily
WM48_RS06665	COG4608	Belongs to the ABC transporter superfamily
WM48_RS06685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WM48_RS06690	COG2350	Protein conserved in bacteria
WM48_RS06700	COG1607	acyl-coa hydrolase
WM48_RS06715	COG3047	cAMP biosynthetic process
WM48_RS06720	COG3685	Protein conserved in bacteria
WM48_RS06725	COG3685	Protein conserved in bacteria
WM48_RS06730	COG3729	General stress protein
WM48_RS06745	COG0134	indole-3-glycerol-phosphate synthase activity
WM48_RS06745	COG0135	phosphoribosylanthranilate isomerase activity
WM48_RS06750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WM48_RS06750	COG0512	Glutamine amidotransferase of anthranilate synthase
WM48_RS06755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WM48_RS06760	COG0613	PHP domain protein
WM48_RS06765	COG0009	L-threonylcarbamoyladenylate synthase
WM48_RS06770	COG4907	membrane protein (DUF2207)
WM48_RS06775	COG1187	pseudouridine synthase activity
WM48_RS06790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
WM48_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS06805	COG0616	signal peptide processing
WM48_RS06820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WM48_RS06825	COG0583	DNA-binding transcription factor activity
WM48_RS06845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WM48_RS06855	COG0671	phosphoesterase, PA-phosphatase related
WM48_RS06860	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
WM48_RS06865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WM48_RS06875	COG0023	Translation Initiation Factor
WM48_RS06885	COG1349	DNA-binding transcription factor activity
WM48_RS06895	COG5001	Diguanylate cyclase
WM48_RS06910	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM48_RS06910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM48_RS06915	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WM48_RS06925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS06930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM48_RS06940	COG2814	Major facilitator Superfamily
WM48_RS06945	COG4172	Belongs to the ABC transporter superfamily
WM48_RS06950	COG4172	Belongs to the ABC transporter superfamily
WM48_RS06955	COG4171	peptide transport system, permease
WM48_RS06960	COG4168	peptide transport system, permease
WM48_RS06965	COG4166	transmembrane transport
WM48_RS06975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WM48_RS06980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WM48_RS06985	COG1842	Phage shock protein A
WM48_RS06995	COG1983	PspC domain protein
WM48_RS07005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WM48_RS07010	COG0366	Alpha amylase catalytic
WM48_RS07015	COG1653	transport
WM48_RS07020	COG1175	transmembrane transport
WM48_RS07025	COG0395	ABC-type sugar transport system, permease component
WM48_RS07030	COG1063	alcohol dehydrogenase
WM48_RS07035	COG1082	Xylose isomerase domain protein TIM barrel
WM48_RS07040	COG0673	inositol 2-dehydrogenase activity
WM48_RS07045	COG1554	hydrolase, family 65, central catalytic
WM48_RS07050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM48_RS07065	COG1609	Transcriptional regulator
WM48_RS07070	COG3106	COG3106 Predicted ATPase
WM48_RS07080	COG3283	Transcriptional regulator of aromatic amino acids metabolism
WM48_RS07085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WM48_RS07090	COG4948	Mandelate Racemase Muconate Lactonizing
WM48_RS07095	COG2866	Carboxypeptidase
WM48_RS07100	COG0702	epimerase
WM48_RS07105	COG1073	alpha beta
WM48_RS07110	COG0583	DNA-binding transcription factor activity
WM48_RS07120	COG4166	transmembrane transport
WM48_RS07125	COG0668	transmembrane transport
WM48_RS07130	COG3182	Iron-regulated membrane protein
WM48_RS07135	COG0589	response to stress
WM48_RS07140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WM48_RS07145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WM48_RS07150	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
WM48_RS07160	COG2207	Transcriptional regulator
WM48_RS07175	COG2840	Smr protein MutS2
WM48_RS07180	COG3706	GGDEF domain
WM48_RS07195	COG0513	Belongs to the DEAD box helicase family
WM48_RS07205	COG0582	viral genome integration into host DNA
WM48_RS07210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WM48_RS07220	COG0589	response to stress
WM48_RS07225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WM48_RS07230	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WM48_RS07230	COG0674	pyruvate-flavodoxin oxidoreductase activity
WM48_RS07230	COG1013	pyruvate-flavodoxin oxidoreductase activity
WM48_RS07230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WM48_RS07235	COG3042	response to heat
WM48_RS07240	COG3187	Heat shock protein
WM48_RS07245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WM48_RS07250	COG2911	Protein conserved in bacteria
WM48_RS07260	COG3784	Protein of unknown function (DUF1318)
WM48_RS07270	COG0667	Aldo Keto reductase
WM48_RS07275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WM48_RS07280	COG4589	Belongs to the CDS family
WM48_RS07285	COG2267	carboxylic ester hydrolase activity
WM48_RS07300	COG1643	Atp-dependent helicase
WM48_RS07305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WM48_RS07310	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS07315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WM48_RS07320	COG3038	cytochrome b561
WM48_RS07335	COG0840	transmembrane signaling receptor activity
WM48_RS07340	COG0840	transmembrane signaling receptor activity
WM48_RS07345	COG0583	DNA-binding transcription factor activity
WM48_RS07350	COG5383	Protein conserved in bacteria
WM48_RS07365	COG2841	Protein conserved in bacteria
WM48_RS07370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM48_RS07375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WM48_RS07380	COG1275	C4-dicarboxylate transporter malic acid transport protein
WM48_RS07385	COG0500	methyltransferase
WM48_RS07395	COG3135	benzoate transporter
WM48_RS07400	COG1396	sequence-specific DNA binding
WM48_RS07405	COG0826	peptidase U32
WM48_RS07415	COG1598	PFAM Uncharacterised protein family UPF0150
WM48_RS07420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WM48_RS07425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WM48_RS07430	COG3842	ATPase activity
WM48_RS07435	COG1176	ABC-type spermidine putrescine transport system, permease component I
WM48_RS07440	COG1177	transmembrane transport
WM48_RS07465	COG3238	Protein conserved in bacteria
WM48_RS07470	COG1247	-acetyltransferase
WM48_RS07475	COG1802	Transcriptional regulator
WM48_RS07480	COG4772	TonB-dependent receptor
WM48_RS07490	COG1113	amino acid transport
WM48_RS07495	COG0625	glutathione transferase activity
WM48_RS07500	COG0625	glutathione transferase activity
WM48_RS07510	COG3501	Rhs element vgr protein
WM48_RS07525	COG5433	transposase activity
WM48_RS07540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WM48_RS07545	COG2162	N-hydroxyarylamine O-acetyltransferase activity
WM48_RS07550	COG0384	phenazine biosynthesis protein PhzF
WM48_RS07555	COG2181	nitrate reductase activity
WM48_RS07560	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WM48_RS07565	COG1140	nitrate reductase beta subunit
WM48_RS07570	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WM48_RS07575	COG2223	nitrite transmembrane transporter activity
WM48_RS07580	COG0697	spore germination
WM48_RS07585	COG3383	formate dehydrogenase (NAD+) activity
WM48_RS07585	COG0243	molybdopterin cofactor binding
WM48_RS07590	COG0243	molybdopterin cofactor binding
WM48_RS07590	COG3383	formate dehydrogenase (NAD+) activity
WM48_RS07595	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS07600	COG2864	formate dehydrogenase
WM48_RS07605	COG3093	addiction module antidote protein HigA
WM48_RS07615	COG1064	alcohol dehydrogenase
WM48_RS07635	COG1764	response to oxidative stress
WM48_RS07640	COG2202	Pas domain
WM48_RS07640	COG2199	diguanylate cyclase activity
WM48_RS07640	COG2200	EAL domain
WM48_RS07645	COG3706	GGDEF domain
WM48_RS07645	COG3706	GGDEF domain
WM48_RS07650	COG1649	PFAM Uncharacterised BCR, COG1649
WM48_RS07655	COG0531	amino acid
WM48_RS07660	COG0076	glutamate decarboxylase activity
WM48_RS07670	COG0612	Peptidase, M16
WM48_RS07675	COG4771	TonB-dependent receptor
WM48_RS07680	COG4178	(ABC) transporter
WM48_RS07685	COG0641	radical SAM
WM48_RS07690	COG3119	arylsulfatase activity
WM48_RS07705	COG0243	molybdopterin cofactor binding
WM48_RS07710	COG3539	Fimbrial protein
WM48_RS07715	COG3539	Fimbrial protein
WM48_RS07720	COG3539	Fimbrial protein
WM48_RS07725	COG3188	usher protein
WM48_RS07735	COG3539	Fimbrial protein
WM48_RS07945	COG3550	peptidyl-serine autophosphorylation
WM48_RS07950	COG1396	sequence-specific DNA binding
WM48_RS07960	COG3781	membrane
WM48_RS07975	COG2199	diguanylate cyclase activity
WM48_RS07985	COG2066	Belongs to the glutaminase family
WM48_RS07990	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS07995	COG0583	DNA-binding transcription factor activity
WM48_RS08010	COG1846	Transcriptional regulator
WM48_RS08015	COG4977	sequence-specific DNA binding
WM48_RS08025	COG2723	6-phospho-beta-galactosidase activity
WM48_RS08035	COG2188	Transcriptional regulator
WM48_RS08040	COG0697	spore germination
WM48_RS08045	COG2814	Major facilitator Superfamily
WM48_RS08055	COG3706	GGDEF domain
WM48_RS08060	COG3111	PFAM Bacterial OB fold (BOF) protein
WM48_RS08065	COG0339	signal peptide processing
WM48_RS08070	COG4221	oxidoreductase activity
WM48_RS08075	COG1802	Transcriptional regulator
WM48_RS08085	COG0246	Mannitol dehydrogenase
WM48_RS08090	COG0477	Major facilitator Superfamily
WM48_RS08095	COG1063	alcohol dehydrogenase
WM48_RS08100	COG4948	Mandelate Racemase Muconate Lactonizing
WM48_RS08115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM48_RS08130	COG3381	protein complex oligomerization
WM48_RS08140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WM48_RS08145	COG1940	carbohydrate kinase activity
WM48_RS08150	COG0583	DNA-binding transcription factor activity
WM48_RS08155	COG2814	Major facilitator Superfamily
WM48_RS08170	COG3591	Belongs to the peptidase S1B family
WM48_RS08185	COG0628	permease
WM48_RS08190	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WM48_RS08195	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WM48_RS08205	COG0531	amino acid
WM48_RS08215	COG3136	membrane protein required for alginate biosynthesis
WM48_RS08220	COG0745	RESPONSE REGULATOR receiver
WM48_RS08225	COG2205	protein histidine kinase activity
WM48_RS08235	COG0114	fumarate hydratase activity
WM48_RS08240	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WM48_RS08240	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WM48_RS08245	COG1482	cell wall glycoprotein biosynthetic process
WM48_RS08250	COG5339	Protein conserved in bacteria
WM48_RS08265	COG3250	beta-galactosidase activity
WM48_RS08270	COG1309	transcriptional regulator
WM48_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS08280	COG1609	Transcriptional regulator
WM48_RS08285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS08285	COG1263	PTS System
WM48_RS08290	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WM48_RS08300	COG0673	inositol 2-dehydrogenase activity
WM48_RS08340	COG4659	FMN binding
WM48_RS08350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WM48_RS08360	COG3104	oligopeptide transport
WM48_RS08365	COG0625	glutathione transferase activity
WM48_RS08385	COG3895	Periplasmic Protein
WM48_RS08395	COG3133	Outer membrane lipoprotein
WM48_RS08410	COG1566	PFAM secretion protein HlyD family protein
WM48_RS08415	COG1289	transmembrane transporter activity
WM48_RS08420	COG2032	superoxide dismutase activity
WM48_RS08425	COG4989	oxidoreductase activity
WM48_RS08430	COG3313	Fe-S protein
WM48_RS08435	COG1309	transcriptional regulator
WM48_RS08440	COG1902	pentaerythritol trinitrate reductase activity
WM48_RS08445	COG0346	lactoylglutathione lyase activity
WM48_RS08460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WM48_RS08465	COG0791	NLP P60 protein
WM48_RS08470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WM48_RS08475	COG2814	Major facilitator Superfamily
WM48_RS08490	COG0583	DNA-binding transcription factor activity
WM48_RS08495	COG2814	Major facilitator Superfamily
WM48_RS08500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WM48_RS08505	COG0307	riboflavin synthase, alpha
WM48_RS08515	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS08535	COG4529	Protein conserved in bacteria
WM48_RS08545	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WM48_RS08550	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS08560	COG2414	aldehyde ferredoxin oxidoreductase
WM48_RS08565	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS08575	COG0469	pyruvate kinase activity
WM48_RS08580	COG4238	major outer membrane lipoprotein
WM48_RS08585	COG1376	ErfK ybiS ycfS ynhG family protein
WM48_RS08600	COG0719	Fe-S assembly protein
WM48_RS08605	COG0396	ATPase activity
WM48_RS08610	COG0719	Fe-S assembly protein
WM48_RS08615	COG0316	Belongs to the HesB IscA family
WM48_RS08625	COG2050	protein possibly involved in aromatic compounds catabolism
WM48_RS08630	COG0277	FAD linked oxidase domain protein
WM48_RS08630	COG0247	lactate metabolic process
WM48_RS08635	COG0628	permease
WM48_RS08650	COG0738	Major facilitator superfamily
WM48_RS08655	COG2271	Major facilitator Superfamily
WM48_RS08670	COG4670	ketone body catabolic process
WM48_RS08675	COG1960	acyl-CoA dehydrogenase activity
WM48_RS08680	COG2207	Transcriptional regulator
WM48_RS08680	COG1917	Cupin 2, conserved barrel domain protein
WM48_RS08690	COG2086	electron transfer activity
WM48_RS08695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WM48_RS08700	COG0644	oxidoreductase
WM48_RS08705	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
WM48_RS08710	COG0318	PFAM AMP-dependent synthetase and ligase
WM48_RS08715	COG0574	Belongs to the PEP-utilizing enzyme family
WM48_RS08715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM48_RS08730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WM48_RS08735	COG4256	Hemin uptake protein
WM48_RS08745	COG2200	EAL domain
WM48_RS08750	COG0791	NLP P60 protein
WM48_RS08760	COG0386	Belongs to the glutathione peroxidase family
WM48_RS08820	COG3137	Salt-induced outer membrane protein
WM48_RS08825	COG1105	Belongs to the carbohydrate kinase PfkB family
WM48_RS08835	COG3001	Fructosamine kinase
WM48_RS08845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM48_RS08850	COG1988	membrane-bound metal-dependent
WM48_RS08855	COG1823	symporter activity
WM48_RS08865	COG0753	catalase activity
WM48_RS08875	COG1486	melibiose metabolic process
WM48_RS08880	COG1917	Cupin 2, conserved barrel domain protein
WM48_RS08880	COG2169	Transcriptional regulator
WM48_RS08885	COG1447	Phosphotransferase system cellobiose-specific component IIA
WM48_RS08890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WM48_RS08895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WM48_RS08900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WM48_RS08915	COG0322	excinuclease ABC activity
WM48_RS08925	COG3678	ATP-independent chaperone mediated protein folding
WM48_RS08955	COG0708	Exodeoxyribonuclease III
WM48_RS08960	COG0398	Pfam SNARE associated Golgi protein
WM48_RS08970	COG0398	Pfam SNARE associated Golgi protein
WM48_RS08975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM48_RS08980	COG4134	Bacterial extracellular solute-binding protein
WM48_RS08985	COG4135	transport system, permease component
WM48_RS08990	COG4136	ATPase activity
WM48_RS08995	COG2897	thiosulfate sulfurtransferase activity
WM48_RS09000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WM48_RS09005	COG0494	nUDIX hydrolase
WM48_RS09015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WM48_RS09030	COG0443	Heat shock 70 kDa protein
WM48_RS09035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WM48_RS09040	COG0709	Synthesizes selenophosphate from selenide and ATP
WM48_RS09050	COG0778	Nitroreductase
WM48_RS09060	COG0616	signal peptide processing
WM48_RS09065	COG0252	asparaginase activity
WM48_RS09070	COG1335	isochorismatase
WM48_RS09075	COG2814	Major facilitator Superfamily
WM48_RS09080	COG1349	DNA-binding transcription factor activity
WM48_RS09085	COG0667	Aldo Keto reductase
WM48_RS09090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS09095	COG0191	fructose-bisphosphate aldolase activity
WM48_RS09100	COG1063	alcohol dehydrogenase
WM48_RS09105	COG2271	Major facilitator Superfamily
WM48_RS09110	COG1063	alcohol dehydrogenase
WM48_RS09115	COG3139	Protein of unknown function (DUF1315)
WM48_RS09125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WM48_RS09130	COG0676	glucose-6-phosphate 1-epimerase activity
WM48_RS09135	COG0656	L-ascorbic acid biosynthetic process
WM48_RS09140	COG3713	MltA-interacting MipA family protein
WM48_RS09145	COG2766	serine protein kinase
WM48_RS09155	COG2199	diguanylate cyclase activity
WM48_RS09160	COG2199	diguanylate cyclase activity
WM48_RS09165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WM48_RS09180	COG2207	Transcriptional regulator
WM48_RS09185	COG2807	transmembrane transport
WM48_RS09190	COG3189	MarR family transcriptional regulator
WM48_RS09195	COG3042	response to heat
WM48_RS09200	COG2199	diguanylate cyclase activity
WM48_RS09200	COG2203	Gaf domain
WM48_RS09210	COG2261	transglycosylase associated protein
WM48_RS09220	COG3615	Tellurite resistance protein tehB
WM48_RS09230	COG0583	DNA-binding transcription factor activity
WM48_RS09235	COG0473	3-isopropylmalate dehydrogenase activity
WM48_RS09240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WM48_RS09245	COG0318	PFAM AMP-dependent synthetase and ligase
WM48_RS09250	COG3065	identical protein binding
WM48_RS09255	COG1214	PFAM Peptidase M22, glycoprotease
WM48_RS09260	COG1199	ATP-dependent helicase activity
WM48_RS09265	COG0251	oxidation-reduction process
WM48_RS09285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WM48_RS09295	COG1760	l-serine dehydratase
WM48_RS09300	COG2200	EAL domain
WM48_RS09305	COG1253	flavin adenine dinucleotide binding
WM48_RS09315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS09315	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS09320	COG3715	PTS system
WM48_RS09325	COG3716	PTS system mannose fructose sorbose family IID component
WM48_RS09345	COG2226	methyltransferase
WM48_RS09380	COG1414	Transcriptional regulator
WM48_RS09385	COG2814	Major facilitator Superfamily
WM48_RS09395	COG0793	Belongs to the peptidase S41A family
WM48_RS09405	COG1956	GAF domain-containing protein
WM48_RS09410	COG2995	paraquat-inducible protein a
WM48_RS09415	COG3008	intermembrane lipid transfer
WM48_RS09435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WM48_RS09450	COG1276	copper resistance
WM48_RS09455	COG2372	response to copper ion
WM48_RS09465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WM48_RS09470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WM48_RS09475	COG1770	oligopeptidase
WM48_RS09480	COG2979	Protein of unknown function (DUF533)
WM48_RS09495	COG3141	response to X-ray
WM48_RS09505	COG0800	Aldolase
WM48_RS09510	COG0129	dihydroxy-acid dehydratase activity
WM48_RS09515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WM48_RS09525	COG1737	Transcriptional regulator
WM48_RS09530	COG0469	pyruvate kinase activity
WM48_RS09535	COG1560	Kdo2-lipid A biosynthetic process
WM48_RS09540	COG0739	heme binding
WM48_RS09545	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WM48_RS09555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WM48_RS09580	COG0217	transcriptional regulatory protein
WM48_RS09585	COG0494	nUDIX hydrolase
WM48_RS09595	COG1335	isochorismatase
WM48_RS09600	COG1801	Protein of unknown function DUF72
WM48_RS09605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WM48_RS09655	COG1801	Protein of unknown function DUF72
WM48_RS09660	COG3788	relative of glutathione S-transferase, MAPEG superfamily
WM48_RS09675	COG0243	molybdopterin cofactor binding
WM48_RS09680	COG3005	denitrification pathway
WM48_RS09690	COG3102	Protein conserved in bacteria
WM48_RS09705	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WM48_RS09715	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WM48_RS09720	COG0745	RESPONSE REGULATOR receiver
WM48_RS09730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WM48_RS09735	COG0840	transmembrane signaling receptor activity
WM48_RS09740	COG0835	chemotaxis
WM48_RS09745	COG0643	Histidine kinase
WM48_RS09745	COG2198	Histidine kinase
WM48_RS09750	COG1360	Flagellar Motor Protein
WM48_RS09755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WM48_RS09770	COG0589	response to stress
WM48_RS09780	COG1877	trehalose-phosphatase activity
WM48_RS09785	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM48_RS09795	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS09800	COG1528	Iron-storage protein
WM48_RS09820	COG1528	Iron-storage protein
WM48_RS09830	COG0814	amino acid
WM48_RS09835	COG3318	Belongs to the UPF0149 family
WM48_RS09835	COG3012	SEC-C Motif Domain Protein
WM48_RS09865	COG2197	response regulator
WM48_RS09880	COG2197	response regulator
WM48_RS09885	COG1126	abc transporter atp-binding protein
WM48_RS09890	COG0765	amino acid transport
WM48_RS09900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS09910	COG1191	sigma factor activity
WM48_RS09920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
WM48_RS09925	COG1516	flagellar protein fliS
WM48_RS09935	COG0366	Alpha amylase catalytic
WM48_RS09945	COG2391	methyltransferase activity
WM48_RS09950	COG0425	Belongs to the sulfur carrier protein TusA family
WM48_RS09955	COG2135	peptidase activity
WM48_RS09965	COG2207	Transcriptional regulator
WM48_RS09970	COG1881	PFAM PEBP family protein
WM48_RS09975	COG2076	Multidrug Resistance protein
WM48_RS09990	COG1766	The M ring may be actively involved in energy transduction
WM48_RS09995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WM48_RS10000	COG1317	bacterial-type flagellum organization
WM48_RS10005	COG1157	protein secretion by the type III secretion system
WM48_RS10010	COG2882	bacterial-type flagellum organization
WM48_RS10015	COG3144	bacterial-type flagellum assembly
WM48_RS10020	COG1580	Controls the rotational direction of flagella during chemotaxis
WM48_RS10025	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WM48_RS10030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WM48_RS10035	COG3190	flagellar
WM48_RS10040	COG1338	Plays a role in the flagellum-specific transport system
WM48_RS10045	COG1987	bacterial-type flagellum assembly
WM48_RS10050	COG1684	flagellar biosynthetic protein fliR
WM48_RS10055	COG2197	response regulator
WM48_RS10080	COG5475	Uncharacterized small protein (DUF2158)
WM48_RS10085	COG2354	Protein conserved in bacteria
WM48_RS10090	COG0697	spore germination
WM48_RS10095	COG3727	T/G mismatch-specific endonuclease activity
WM48_RS10100	COG0270	DNA (cytosine-5-)-methyltransferase activity
WM48_RS10105	COG1418	mRNA catabolic process
WM48_RS10120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WM48_RS10135	COG2205	protein histidine kinase activity
WM48_RS10140	COG0745	RESPONSE REGULATOR receiver
WM48_RS10145	COG2351	hydroxyisourate hydrolase activity
WM48_RS10160	COG3443	Belongs to the bacterial solute-binding protein 9 family
WM48_RS10170	COG0582	viral genome integration into host DNA
WM48_RS10200	COG4916	TIR domain
WM48_RS10310	COG0582	viral genome integration into host DNA
WM48_RS10320	COG2814	Major facilitator Superfamily
WM48_RS10325	COG1132	(ABC) transporter
WM48_RS10360	COG1021	2,3-dihydroxybenzoate-AMP ligase
WM48_RS10365	COG4771	TonB-dependent receptor
WM48_RS10370	COG4932	domain protein
WM48_RS10370	COG1388	LysM domain
WM48_RS10370	COG2373	Large extracellular alpha-helical protein
WM48_RS10375	COG1470	cell adhesion involved in biofilm formation
WM48_RS10375	COG1388	LysM domain
WM48_RS10380	COG1470	cell adhesion involved in biofilm formation
WM48_RS10380	COG1388	LysM domain
WM48_RS10385	COG1388	LysM domain
WM48_RS10385	COG1470	cell adhesion involved in biofilm formation
WM48_RS10395	COG0477	Major facilitator Superfamily
WM48_RS10400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WM48_RS10405	COG0217	transcriptional regulatory protein
WM48_RS10415	COG0583	DNA-binding transcription factor activity
WM48_RS10420	COG0583	DNA-binding transcription factor activity
WM48_RS10430	COG0534	Mate efflux family protein
WM48_RS10440	COG0582	viral genome integration into host DNA
WM48_RS10480	COG0154	amidase activity
WM48_RS10510	COG1960	acyl-CoA dehydrogenase activity
WM48_RS10515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WM48_RS10520	COG1250	3-hydroxyacyl-CoA dehydrogenase
WM48_RS10535	COG2197	response regulator
WM48_RS10550	COG2801	Transposase and inactivated derivatives
WM48_RS10560	COG1376	ErfK ybiS ycfS ynhG family protein
WM48_RS10575	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
WM48_RS10585	COG4771	TonB-dependent receptor
WM48_RS10590	COG1475	DNA binding
WM48_RS10595	COG3969	phosphoadenosine phosphosulfate
WM48_RS10600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
WM48_RS10605	COG1215	transferase activity, transferring glycosyl groups
WM48_RS10625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS10640	COG1735	metal-dependent hydrolase with the TIM-barrel fold
WM48_RS10645	COG0405	Gamma-glutamyltransferase
WM48_RS10695	COG3547	Transposase (IS116 IS110 IS902 family)
WM48_RS10735	COG1120	ATPase activity
WM48_RS10740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS10800	COG2003	Belongs to the UPF0758 family
WM48_RS10840	COG1289	transmembrane transporter activity
WM48_RS10850	COG1686	Belongs to the peptidase S11 family
WM48_RS10855	COG2925	Exonuclease
WM48_RS10860	COG0531	amino acid
WM48_RS10865	COG0583	DNA-binding transcription factor activity
WM48_RS10870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WM48_RS10875	COG4115	mRNA cleavage
WM48_RS10880	COG2161	toxin-antitoxin pair type II binding
WM48_RS10890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WM48_RS10900	COG0131	Imidazoleglycerol-phosphate dehydratase
WM48_RS10900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WM48_RS10905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WM48_RS10920	COG0140	phosphoribosyl-ATP diphosphatase activity
WM48_RS10920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WM48_RS10925	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
WM48_RS10930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WM48_RS10935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
WM48_RS10940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WM48_RS10955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WM48_RS10970	COG1216	Glycosyl transferase, family 2
WM48_RS10985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WM48_RS10995	COG0438	transferase activity, transferring glycosyl groups
WM48_RS11000	COG2327	Polysaccharide pyruvyl transferase
WM48_RS11005	COG2244	polysaccharide biosynthetic process
WM48_RS11010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WM48_RS11015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WM48_RS11020	COG0662	Cupin 2, conserved barrel domain protein
WM48_RS11020	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
WM48_RS11025	COG0297	glycogen (starch) synthase activity
WM48_RS11030	COG1051	belongs to the nudix hydrolase family
WM48_RS11035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WM48_RS11040	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
WM48_RS11045	COG0110	maltose O-acetyltransferase activity
WM48_RS11050	COG1216	Glycosyl transferase, family 2
WM48_RS11060	COG0438	transferase activity, transferring glycosyl groups
WM48_RS11065	COG1045	serine acetyltransferase
WM48_RS11070	COG0463	Glycosyl transferase, family 2
WM48_RS11075	COG3206	protein involved in exopolysaccharide biosynthesis
WM48_RS11075	COG0489	protein tyrosine kinase activity
WM48_RS11080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WM48_RS11085	COG1596	polysaccharide export
WM48_RS11090	COG1253	flavin adenine dinucleotide binding
WM48_RS11095	COG2982	Protein involved in outer membrane biogenesis
WM48_RS11105	COG0572	uridine kinase
WM48_RS11110	COG5002	protein histidine kinase activity
WM48_RS11110	COG5001	Diguanylate cyclase
WM48_RS11110	COG3447	MASE1 domain protein
WM48_RS11115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WM48_RS11120	COG0443	Heat shock 70 kDa protein
WM48_RS11125	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
WM48_RS11130	COG0631	protein serine/threonine phosphatase activity
WM48_RS11135	COG4245	von Willebrand factor, type A
WM48_RS11160	COG2205	protein histidine kinase activity
WM48_RS11165	COG0745	RESPONSE REGULATOR receiver
WM48_RS11195	COG0826	peptidase U32
WM48_RS11215	COG1063	alcohol dehydrogenase
WM48_RS11220	COG3775	system Galactitol-specific IIC component
WM48_RS11225	COG3414	Phosphotransferase system galactitol-specific IIB component
WM48_RS11230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS11245	COG1830	Aldolase
WM48_RS11250	COG2211	Major facilitator Superfamily
WM48_RS11255	COG1397	ADP-ribosylglycohydrolase
WM48_RS11260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS11265	COG2188	Transcriptional regulator
WM48_RS11270	COG3757	hydrolase, family 25
WM48_RS11275	COG0351	phosphomethylpyrimidine kinase
WM48_RS11295	COG5455	response to cobalt ion
WM48_RS11300	COG3539	Fimbrial protein
WM48_RS11305	COG3188	usher protein
WM48_RS11310	COG3121	Chaperone
WM48_RS11315	COG3539	Fimbrial protein
WM48_RS11330	COG0489	protein tyrosine kinase activity
WM48_RS11340	COG3831	ATPase activity
WM48_RS11345	COG3831	ATPase activity
WM48_RS11360	COG0714	Associated with various cellular activities
WM48_RS11365	COG2425	protein containing a von Willebrand factor type A (vWA) domain
WM48_RS11370	COG3552	Protein containing von Willebrand factor type A (VWA) domain
WM48_RS11375	COG4715	Zinc finger, swim domain protein
WM48_RS11380	COG4715	Zinc finger, swim domain protein
WM48_RS11385	COG4808	Protein conserved in bacteria
WM48_RS11390	COG4807	Protein conserved in bacteria
WM48_RS11395	COG3279	Response regulator of the LytR AlgR family
WM48_RS11400	COG3275	phosphorelay sensor kinase activity
WM48_RS11405	COG0789	Transcriptional regulator
WM48_RS11415	COG1174	glycine betaine transport
WM48_RS11420	COG1125	glycine betaine transport
WM48_RS11425	COG1174	glycine betaine transport
WM48_RS11430	COG1732	Glycine betaine
WM48_RS11435	COG1472	Belongs to the glycosyl hydrolase 3 family
WM48_RS11440	COG0277	FAD linked oxidase domain protein
WM48_RS11445	COG1686	Belongs to the peptidase S11 family
WM48_RS11455	COG0586	Pfam SNARE associated Golgi protein
WM48_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS11465	COG1538	Outer membrane efflux protein
WM48_RS11475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WM48_RS11485	COG1346	cytolysis
WM48_RS11495	COG2949	membrane
WM48_RS11505	COG0493	'glutamate synthase
WM48_RS11510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WM48_RS11510	COG0167	dihydroorotate dehydrogenase activity
WM48_RS11515	COG4211	Belongs to the binding-protein-dependent transport system permease family
WM48_RS11525	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS11530	COG1609	Transcriptional regulator
WM48_RS11540	COG2311	Membrane
WM48_RS11560	COG4771	TonB-dependent receptor
WM48_RS11570	COG0833	amino acid
WM48_RS11575	COG0583	DNA-binding transcription factor activity
WM48_RS11580	COG2855	membrane
WM48_RS11590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS11590	COG1522	sequence-specific DNA binding
WM48_RS11595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WM48_RS11605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WM48_RS11610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WM48_RS11615	COG2313	pseudouridylate synthase activity
WM48_RS11620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS11625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS11625	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WM48_RS11625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS11630	COG1105	Belongs to the carbohydrate kinase PfkB family
WM48_RS11635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS11635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS11640	COG2814	Major facilitator Superfamily
WM48_RS11655	COG0246	Mannitol dehydrogenase
WM48_RS11660	COG0523	cobalamin synthesis protein
WM48_RS11665	COG0671	phosphoesterase, PA-phosphatase related
WM48_RS11670	COG0791	NLP P60 protein
WM48_RS11675	COG2200	EAL domain
WM48_RS11680	COG4166	transmembrane transport
WM48_RS11685	COG4174	ABC transporter (Permease)
WM48_RS11690	COG4239	(ABC) transporter, permease
WM48_RS11695	COG4172	Belongs to the ABC transporter superfamily
WM48_RS11705	COG2814	Major facilitator Superfamily
WM48_RS11710	COG1187	pseudouridine synthase activity
WM48_RS11715	COG1061	Type III restriction enzyme res subunit
WM48_RS11735	COG3083	sulfuric ester hydrolase activity
WM48_RS11745	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS11750	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS11760	COG2197	response regulator
WM48_RS11765	COG4235	cytochrome complex assembly
WM48_RS11765	COG3088	subunit of a heme lyase
WM48_RS11770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WM48_RS11785	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WM48_RS11790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WM48_RS11795	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WM48_RS11800	COG4133	protoheme IX ABC transporter activity
WM48_RS11805	COG3005	denitrification pathway
WM48_RS11810	COG3043	anaerobic respiration
WM48_RS11815	COG0348	domain, Protein
WM48_RS11820	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS11830	COG3062	negative regulation of establishment of protein localization
WM48_RS11835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS11835	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS11855	COG4615	Cyclic peptide transporter
WM48_RS11860	COG3145	DNA-N1-methyladenine dioxygenase activity
WM48_RS11865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WM48_RS11865	COG2169	Transcriptional regulator
WM48_RS11870	COG1477	protein flavinylation
WM48_RS11875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
WM48_RS11885	COG2198	Histidine kinase
WM48_RS11885	COG0642	Histidine kinase
WM48_RS11890	COG2197	response regulator
WM48_RS11895	COG2205	protein histidine kinase activity
WM48_RS11895	COG0784	Response regulator, receiver
WM48_RS11900	COG3852	Histidine kinase
WM48_RS11905	COG2204	response regulator
WM48_RS11910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WM48_RS11915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WM48_RS11920	COG2031	fatty acid transporter
WM48_RS11925	COG0183	Belongs to the thiolase family
WM48_RS11930	COG4676	Protein conserved in bacteria
WM48_RS11935	COG5445	Predicted secreted protein (DUF2300)
WM48_RS11940	COG2373	Large extracellular alpha-helical protein
WM48_RS11945	COG3234	Protein of unknown function (DUF1175)
WM48_RS11950	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
WM48_RS11955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WM48_RS11965	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS11975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WM48_RS11980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WM48_RS11985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WM48_RS11990	COG3642	lipopolysaccharide core region biosynthetic process
WM48_RS11995	COG0584	glycerophosphoryl diester phosphodiesterase
WM48_RS12000	COG2271	Major facilitator Superfamily
WM48_RS12005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WM48_RS12015	COG0247	lactate metabolic process
WM48_RS12025	COG5464	transposase or invertase
WM48_RS12040	COG2271	Major facilitator Superfamily
WM48_RS12050	COG1414	Transcriptional regulator
WM48_RS12115	COG0318	PFAM AMP-dependent synthetase and ligase
WM48_RS12125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WM48_RS12140	COG1169	isochorismate synthase
WM48_RS12145	COG4575	ribosome binding
WM48_RS12150	COG2153	protein acetylation
WM48_RS12160	COG5160	protein modification by small protein removal
WM48_RS12165	COG2234	aminopeptidase activity
WM48_RS12180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WM48_RS12185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WM48_RS12195	COG0839	Belongs to the complex I subunit 6 family
WM48_RS12210	COG1034	ATP synthesis coupled electron transport
WM48_RS12215	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
WM48_RS12220	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WM48_RS12240	COG0583	DNA-binding transcription factor activity
WM48_RS12245	COG0436	Aminotransferase
WM48_RS12255	COG0471	metal ion transport
WM48_RS12255	COG0490	domain, Protein
WM48_RS12260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM48_RS12280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WM48_RS12285	COG0280	phosphate acetyltransferase
WM48_RS12285	COG0857	belongs to the CobB CobQ family
WM48_RS12290	COG1288	antiporter activity
WM48_RS12295	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
WM48_RS12300	COG0622	Phosphoesterase
WM48_RS12305	COG0625	glutathione transferase activity
WM48_RS12310	COG0625	glutathione transferase activity
WM48_RS12315	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WM48_RS12320	COG1090	epimerase
WM48_RS12325	COG5464	transposase or invertase
WM48_RS12330	COG4598	ABC transporter
WM48_RS12335	COG4160	amino acid transport
WM48_RS12340	COG4215	(ABC) transporter
WM48_RS12345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS12350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS12355	COG0163	prenyltransferase activity
WM48_RS12360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WM48_RS12365	COG1286	toxin biosynthetic process
WM48_RS12370	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
WM48_RS12375	COG0285	dihydrofolate synthase activity
WM48_RS12385	COG0586	Pfam SNARE associated Golgi protein
WM48_RS12395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WM48_RS12410	COG2814	Major facilitator Superfamily
WM48_RS12415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WM48_RS12430	COG3101	peptidyl-lysine hydroxylation
WM48_RS12435	COG0730	response to heat
WM48_RS12470	COG3539	Fimbrial protein
WM48_RS12475	COG3539	Fimbrial protein
WM48_RS12480	COG3539	Fimbrial protein
WM48_RS12485	COG3121	Chaperone
WM48_RS12490	COG3188	usher protein
WM48_RS12495	COG3539	Fimbrial protein
WM48_RS12500	COG2062	phosphohistidine phosphatase, SixA
WM48_RS12515	COG3691	Protein conserved in bacteria
WM48_RS12520	COG2067	long-chain fatty acid transport protein
WM48_RS12530	COG2116	formate transmembrane transporter activity
WM48_RS12565	COG2610	gluconate transmembrane transporter activity
WM48_RS12575	COG0477	Major facilitator Superfamily
WM48_RS12580	COG1566	PFAM secretion protein HlyD family protein
WM48_RS12585	COG2197	response regulator
WM48_RS12590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS12590	COG0784	Response regulator, receiver
WM48_RS12590	COG2205	protein histidine kinase activity
WM48_RS12590	COG2198	Histidine kinase
WM48_RS12595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WM48_RS12600	COG0679	Auxin Efflux Carrier
WM48_RS12605	COG0028	Belongs to the TPP enzyme family
WM48_RS12635	COG1560	Kdo2-lipid A biosynthetic process
WM48_RS12640	COG0436	Aminotransferase
WM48_RS12645	COG3275	phosphorelay sensor kinase activity
WM48_RS12650	COG3279	Response regulator of the LytR AlgR family
WM48_RS12655	COG2207	Transcriptional regulator
WM48_RS12660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM48_RS12660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS12660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS12665	COG1363	Peptidase, m42
WM48_RS12670	COG0006	proline dipeptidase activity
WM48_RS12675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS12680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS12710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WM48_RS12715	COG2199	diguanylate cyclase activity
WM48_RS12715	COG2200	EAL domain
WM48_RS12730	COG3415	Transposase
WM48_RS12735	COG3415	Transposase
WM48_RS12765	COG0583	DNA-binding transcription factor activity
WM48_RS12775	COG2211	Major facilitator Superfamily
WM48_RS12780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
WM48_RS12790	COG0583	DNA-binding transcription factor activity
WM48_RS12795	COG0385	Bile acid
WM48_RS12800	COG3530	Putative quorum-sensing-regulated virulence factor
WM48_RS12820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WM48_RS12825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS12830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM48_RS12835	COG2190	(PTS) system
WM48_RS12850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WM48_RS12855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WM48_RS12860	COG4208	sulfate ABC transporter
WM48_RS12865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WM48_RS12870	COG4150	thiosulfate binding
WM48_RS12875	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS12885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS12885	COG1263	PTS System
WM48_RS12890	COG2837	iron assimilation
WM48_RS12910	COG0860	N-Acetylmuramoyl-L-alanine amidase
WM48_RS12920	COG2207	Transcriptional regulator
WM48_RS12925	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
WM48_RS12930	COG4816	utilization protein
WM48_RS12940	COG4303	Ethanolamine ammonia lyase large subunit
WM48_RS12945	COG4819	ethanolamine utilization protein
WM48_RS12950	COG3192	ethanolamine utilization protein
WM48_RS12955	COG1454	alcohol dehydrogenase
WM48_RS12960	COG4820	ethanolamine utilization protein (EutJ)
WM48_RS12965	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS12970	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
WM48_RS12975	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
WM48_RS12980	COG0280	phosphate acetyltransferase
WM48_RS12985	COG4812	Cobalamin adenosyltransferase
WM48_RS12990	COG4766	ethanolamine catabolic process
WM48_RS12995	COG4917	ethanolamine utilization protein
WM48_RS13000	COG4810	utilization protein
WM48_RS13005	COG0281	malic enzyme
WM48_RS13005	COG0280	phosphate acetyltransferase
WM48_RS13010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WM48_RS13015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WM48_RS13020	COG5342	invasion associated locus B
WM48_RS13030	COG0493	'glutamate synthase
WM48_RS13030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS13035	COG3850	Histidine kinase
WM48_RS13040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM48_RS13050	COG1393	Belongs to the ArsC family
WM48_RS13065	COG0400	carboxylic ester hydrolase activity
WM48_RS13075	COG2321	neutral zinc metallopeptidase
WM48_RS13090	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WM48_RS13100	COG2716	regulation of RNA biosynthetic process
WM48_RS13105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WM48_RS13110	COG0628	permease
WM48_RS13115	COG4783	chaperone-mediated protein folding
WM48_RS13120	COG1393	Belongs to the ArsC family
WM48_RS13130	COG2233	PERMEase
WM48_RS13145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WM48_RS13150	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WM48_RS13155	COG0248	Ppx GppA phosphatase
WM48_RS13160	COG2200	EAL domain
WM48_RS13175	COG3133	Outer membrane lipoprotein
WM48_RS13190	COG3179	chitinase
WM48_RS13335	COG5484	DNA packaging
WM48_RS13335	COG3728	DNA packaging
WM48_RS13405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WM48_RS13445	COG0516	GMP reductase activity
WM48_RS13445	COG0517	IMP dehydrogenase activity
WM48_RS13470	COG1645	bacterial-type flagellum-dependent swarming motility
WM48_RS13485	COG2976	Protein conserved in bacteria
WM48_RS13515	COG4953	penicillin-binding protein 1C
WM48_RS13520	COG2373	Large extracellular alpha-helical protein
WM48_RS13525	COG2897	thiosulfate sulfurtransferase activity
WM48_RS13540	COG2975	iron-sulfur cluster assembly
WM48_RS13545	COG0633	Ferredoxin
WM48_RS13565	COG0822	iron-sulfur transferase activity
WM48_RS13585	COG0483	inositol monophosphate 1-phosphatase activity
WM48_RS13590	COG1073	alpha beta
WM48_RS13595	COG3711	transcriptional antiterminator
WM48_RS13600	COG2814	Major facilitator Superfamily
WM48_RS13605	COG2259	Doxx family
WM48_RS13615	COG2801	Transposase and inactivated derivatives
WM48_RS13620	COG2017	converts alpha-aldose to the beta-anomer
WM48_RS13625	COG1063	alcohol dehydrogenase
WM48_RS13630	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM48_RS13635	COG1129	ABC transporter
WM48_RS13640	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS13645	COG0457	Tetratricopeptide repeat
WM48_RS13650	COG1940	carbohydrate kinase activity
WM48_RS13660	COG1017	nitric oxide dioxygenase activity
WM48_RS13660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WM48_RS13665	COG0347	Belongs to the P(II) protein family
WM48_RS13670	COG2204	response regulator
WM48_RS13675	COG3170	Tfp pilus assembly protein FimV
WM48_RS13680	COG2205	protein histidine kinase activity
WM48_RS13695	COG0590	tRNA wobble adenosine to inosine editing
WM48_RS13700	COG0560	Phosphoserine phosphatase
WM48_RS13705	COG1737	Transcriptional regulator
WM48_RS13720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WM48_RS13735	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WM48_RS13860	COG1783	phage Terminase large subunit
WM48_RS13965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS13985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WM48_RS14005	COG0681	Belongs to the peptidase S26 family
WM48_RS14015	COG3086	response to oxidative stress
WM48_RS14020	COG3026	antisigma factor binding
WM48_RS14025	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
WM48_RS14030	COG1595	DNA-templated transcription, initiation
WM48_RS14040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WM48_RS14050	COG0513	Belongs to the DEAD box helicase family
WM48_RS14055	COG0583	DNA-binding transcription factor activity
WM48_RS14075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WM48_RS14085	COG3118	belongs to the thioredoxin family
WM48_RS14090	COG3148	PFAM DTW domain containing protein
WM48_RS14095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WM48_RS14095	COG1042	CoA-binding domain protein
WM48_RS14095	COG0045	succinate-CoA ligase (ADP-forming) activity
WM48_RS14100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM48_RS14105	COG5544	Lipoprotein
WM48_RS14110	COG0477	Major facilitator Superfamily
WM48_RS14140	COG2801	Transposase and inactivated derivatives
WM48_RS14175	COG0542	response to heat
WM48_RS14185	COG0564	pseudouridine synthase activity
WM48_RS14190	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WM48_RS14200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WM48_RS14205	COG0077	Prephenate dehydratase
WM48_RS14205	COG1605	Chorismate mutase
WM48_RS14210	COG0287	Prephenate dehydrogenase
WM48_RS14210	COG1605	Chorismate mutase
WM48_RS14215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WM48_RS14230	COG2199	diguanylate cyclase activity
WM48_RS14235	COG2885	chlorophyll binding
WM48_RS14260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WM48_RS14265	COG4137	Cytochrome C assembly protein
WM48_RS14270	COG4536	flavin adenine dinucleotide binding
WM48_RS14285	COG0497	DNA recombination
WM48_RS14290	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WM48_RS14300	COG2867	negative regulation of translational initiation
WM48_RS14320	COG0579	oxidoreductase
WM48_RS14325	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS14330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WM48_RS14335	COG1113	amino acid transport
WM48_RS14340	COG1802	Transcriptional regulator
WM48_RS14345	COG1652	LysM domain
WM48_RS14350	COG0401	homolog of Blt101
WM48_RS14355	COG0640	Transcriptional regulator
WM48_RS14360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WM48_RS14365	COG2916	Histone family protein nucleoid-structuring protein H-NS
WM48_RS14380	COG4575	ribosome binding
WM48_RS14390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WM48_RS14395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WM48_RS14405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WM48_RS14410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WM48_RS14415	COG4175	Glycine betaine
WM48_RS14420	COG4176	ABC-type proline glycine betaine transport system permease component
WM48_RS14425	COG2113	Glycine betaine
WM48_RS14430	COG2814	Major facilitator Superfamily
WM48_RS14435	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WM48_RS14445	COG1846	Transcriptional regulator
WM48_RS14450	COG1566	PFAM secretion protein HlyD family protein
WM48_RS14455	COG2814	Major facilitator Superfamily
WM48_RS14470	COG1238	metal cluster binding
WM48_RS14475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM48_RS14505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
WM48_RS14530	COG1546	Belongs to the CinA family
WM48_RS14535	COG2951	lytic endotransglycosylase activity
WM48_RS14540	COG3730	PTS system glucitol sorbitol-specific
WM48_RS14545	COG3732	PTS system glucitol sorbitol-specific
WM48_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS14560	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS14565	COG1349	DNA-binding transcription factor activity
WM48_RS14570	COG0517	IMP dehydrogenase activity
WM48_RS14570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WM48_RS14590	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
WM48_RS14595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS14600	COG1609	Transcriptional regulator
WM48_RS14605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS14605	COG1263	PTS System
WM48_RS14610	COG2723	6-phospho-beta-galactosidase activity
WM48_RS14615	COG5499	transcription regulator containing HTH domain
WM48_RS14620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WM48_RS14630	COG3260	NADH ubiquinone oxidoreductase 20
WM48_RS14635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WM48_RS14640	COG3261	NADH dehydrogenase
WM48_RS14640	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
WM48_RS14645	COG0650	Formate hydrogenlyase subunit 4
WM48_RS14650	COG0651	ATP synthesis coupled electron transport
WM48_RS14655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS14670	COG0375	protein maturation
WM48_RS14675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WM48_RS14680	COG0298	carbon dioxide binding
WM48_RS14685	COG0409	Hydrogenase expression formation protein
WM48_RS14690	COG0309	Hydrogenase expression formation protein (HypE)
WM48_RS14695	COG3604	Transcriptional regulator
WM48_RS14725	COG3335	DDE superfamily endonuclease
WM48_RS14765	COG1349	DNA-binding transcription factor activity
WM48_RS14770	COG2084	Dehydrogenase
WM48_RS14775	COG3395	kinase activity
WM48_RS14780	COG0235	Class ii aldolase
WM48_RS14785	COG3622	Belongs to the hyi family
WM48_RS14790	COG2610	gluconate transmembrane transporter activity
WM48_RS14805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WM48_RS14810	COG1388	LysM domain
WM48_RS14810	COG4942	peptidase
WM48_RS14865	COG2234	aminopeptidase activity
WM48_RS14890	COG0720	synthase
WM48_RS14895	COG0644	oxidoreductase
WM48_RS14900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
WM48_RS14905	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WM48_RS14910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WM48_RS14915	COG2086	electron transfer activity
WM48_RS14920	COG0477	Major facilitator Superfamily
WM48_RS14925	COG0277	FAD linked oxidase domain protein
WM48_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS14935	COG2223	nitrite transmembrane transporter activity
WM48_RS14940	COG1070	Carbohydrate kinase
WM48_RS14970	COG0602	queuosine metabolic process
WM48_RS14980	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WM48_RS14990	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WM48_RS15005	COG3956	TIGRFAM MazG family protein
WM48_RS15010	COG2337	Toxic component of a toxin-antitoxin (TA) module
WM48_RS15015	COG2336	PFAM SpoVT AbrB
WM48_RS15020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WM48_RS15030	COG3850	Histidine kinase
WM48_RS15030	COG4999	Histidine kinase
WM48_RS15030	COG3437	response regulator, receiver
WM48_RS15030	COG2205	protein histidine kinase activity
WM48_RS15035	COG4948	Mandelate Racemase Muconate Lactonizing
WM48_RS15040	COG4948	Mandelate Racemase Muconate Lactonizing
WM48_RS15045	COG2271	Major facilitator Superfamily
WM48_RS15050	COG0716	FMN binding
WM48_RS15055	COG0564	pseudouridine synthase activity
WM48_RS15060	COG3098	single-species biofilm formation
WM48_RS15080	COG1611	Belongs to the LOG family
WM48_RS15085	COG0814	amino acid
WM48_RS15090	COG1760	l-serine dehydratase
WM48_RS15100	COG1454	alcohol dehydrogenase
WM48_RS15105	COG0235	Class ii aldolase
WM48_RS15110	COG0738	Major facilitator superfamily
WM48_RS15120	COG1070	Carbohydrate kinase
WM48_RS15130	COG1349	DNA-binding transcription factor activity
WM48_RS15140	COG2363	Small membrane protein
WM48_RS15145	COG0583	DNA-binding transcription factor activity
WM48_RS15155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WM48_RS15160	COG2166	iron-sulfur cluster assembly
WM48_RS15165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WM48_RS15170	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WM48_RS15210	COG2885	chlorophyll binding
WM48_RS15310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WM48_RS15315	COG1263	PTS System
WM48_RS15315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS15320	COG3711	transcriptional antiterminator
WM48_RS15325	COG0860	N-Acetylmuramoyl-L-alanine amidase
WM48_RS15330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WM48_RS15330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WM48_RS15335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WM48_RS15340	COG1074	ATP-dependent DNA helicase activity
WM48_RS15345	COG1025	Belongs to the peptidase M16 family
WM48_RS15350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WM48_RS15355	COG4967	type IV pilus modification protein PilV
WM48_RS15365	COG4795	General secretion pathway protein
WM48_RS15370	COG2165	general secretion pathway protein
WM48_RS15385	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
WM48_RS15410	COG0861	Integral membrane protein TerC family
WM48_RS15420	COG0667	Aldo Keto reductase
WM48_RS15435	COG1609	Transcriptional regulator
WM48_RS15445	COG0583	DNA-binding transcription factor activity
WM48_RS15450	COG1794	racemase activity, acting on amino acids and derivatives
WM48_RS15455	COG2814	Major facilitator Superfamily
WM48_RS15460	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS15470	COG0183	Belongs to the thiolase family
WM48_RS15475	COG0814	amino acid
WM48_RS15485	COG4942	peptidase
WM48_RS15490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WM48_RS15495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WM48_RS15500	COG2080	2 iron, 2 sulfur cluster binding
WM48_RS15505	COG3829	transcription factor binding
WM48_RS15510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WM48_RS15515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WM48_RS15520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WM48_RS15530	COG0549	Belongs to the carbamate kinase family
WM48_RS15535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WM48_RS15535	COG3608	succinylglutamate desuccinylase aspartoacylase
WM48_RS15540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WM48_RS15545	COG2068	MobA-Related Protein
WM48_RS15550	COG0493	'glutamate synthase
WM48_RS15550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS15555	COG0402	S-adenosylhomocysteine deaminase activity
WM48_RS15560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WM48_RS15565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WM48_RS15565	COG2080	2 iron, 2 sulfur cluster binding
WM48_RS15570	COG2233	PERMEase
WM48_RS15575	COG0402	S-adenosylhomocysteine deaminase activity
WM48_RS15580	COG2252	PERMEase
WM48_RS15585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS15590	COG0493	'glutamate synthase
WM48_RS15590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS15600	COG2233	PERMEase
WM48_RS15615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WM48_RS15625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WM48_RS15630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WM48_RS15635	COG4974	Belongs to the 'phage' integrase family
WM48_RS15640	COG0716	FMN binding
WM48_RS15650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WM48_RS15660	COG1272	protein, Hemolysin III
WM48_RS15670	COG2723	6-phospho-beta-galactosidase activity
WM48_RS15690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WM48_RS15695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WM48_RS15700	COG0006	proline dipeptidase activity
WM48_RS15720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WM48_RS15730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WM48_RS15750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
WM48_RS15750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
WM48_RS15755	COG0583	DNA-binding transcription factor activity
WM48_RS15760	COG2968	Membrane
WM48_RS15765	COG1279	arginine transmembrane transporter activity
WM48_RS15770	COG0668	transmembrane transport
WM48_RS15775	COG0191	fructose-bisphosphate aldolase activity
WM48_RS15810	COG1122	ATPase activity
WM48_RS15815	COG1072	(Pantothenic acid kinase))
WM48_RS15825	COG1494	fructose-1,6-bisphosphatase
WM48_RS15830	COG1063	alcohol dehydrogenase
WM48_RS15835	COG2213	PTS system mannitol-specific
WM48_RS15840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS15845	COG0330	HflC and HflK could
WM48_RS15850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WM48_RS15855	COG0501	Belongs to the peptidase M48B family
WM48_RS15870	COG1166	arginine decarboxylase activity
WM48_RS15895	COG2814	Major facilitator Superfamily
WM48_RS15905	COG2356	endonuclease I
WM48_RS15910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WM48_RS15915	COG0189	ligase activity
WM48_RS15930	COG2805	Type II/IV secretion system protein
WM48_RS15935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WM48_RS15940	COG0762	integral membrane protein
WM48_RS15950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WM48_RS15955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WM48_RS15965	COG0252	asparaginase activity
WM48_RS15980	COG3171	Protein conserved in bacteria
WM48_RS15990	COG1194	a g-specific adenine glycosylase
WM48_RS16005	COG2211	Major facilitator Superfamily
WM48_RS16010	COG1982	Orn Lys Arg decarboxylase major
WM48_RS16015	COG1811	Na channel or pump
WM48_RS16025	COG0582	viral genome integration into host DNA
WM48_RS16035	COG2194	sulfuric ester hydrolase activity
WM48_RS16160	COG3210	domain, Protein
WM48_RS16165	COG3210	domain, Protein
WM48_RS16200	COG2814	Major facilitator Superfamily
WM48_RS16205	COG0673	inositol 2-dehydrogenase activity
WM48_RS16250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS16260	COG3037	sugar-specific permease SgaT UlaA
WM48_RS16275	COG0738	Major facilitator superfamily
WM48_RS16285	COG1349	DNA-binding transcription factor activity
WM48_RS16290	COG0440	acetolactate synthase activity
WM48_RS16295	COG0440	acetolactate synthase activity
WM48_RS16345	COG4983	Phage plasmid primase, P4 family domain protein
WM48_RS16355	COG3468	outer membrane autotransporter barrel domain protein
WM48_RS16385	COG2003	Belongs to the UPF0758 family
WM48_RS16485	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WM48_RS16515	COG2165	general secretion pathway protein
WM48_RS16520	COG1459	type II secretion system
WM48_RS16525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WM48_RS16550	COG3064	Membrane
WM48_RS16565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WM48_RS16570	COG3193	protein, possibly involved in utilization of glycolate and propanediol
WM48_RS16575	COG0247	lactate metabolic process
WM48_RS16580	COG0277	FAD linked oxidase domain protein
WM48_RS16585	COG0277	FAD linked oxidase domain protein
WM48_RS16590	COG2186	Transcriptional regulator
WM48_RS16595	COG0456	acetyltransferase
WM48_RS16610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WM48_RS16615	COG0156	8-amino-7-oxononanoate synthase activity
WM48_RS16625	COG0795	lipopolysaccharide-transporting ATPase activity
WM48_RS16630	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WM48_RS16640	COG2244	polysaccharide biosynthetic process
WM48_RS16645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WM48_RS16650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WM48_RS16655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WM48_RS16660	COG0306	phosphate transporter
WM48_RS16665	COG0754	glutathionylspermidine amidase activity
WM48_RS16670	COG0625	glutathione transferase activity
WM48_RS16675	COG0298	carbon dioxide binding
WM48_RS16680	COG0375	protein maturation
WM48_RS16685	COG1773	rubredoxin
WM48_RS16690	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WM48_RS16695	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WM48_RS16700	COG5557	Pfam Polysulphide reductase, NrfD
WM48_RS16705	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS16710	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WM48_RS16730	COG0667	Aldo Keto reductase
WM48_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS16745	COG0848	biopolymer transport protein
WM48_RS16750	COG0811	peptide transport
WM48_RS16760	COG0626	cystathionine gamma-synthase activity
WM48_RS16765	COG0586	Pfam SNARE associated Golgi protein
WM48_RS16770	COG2207	Transcriptional regulator
WM48_RS16780	COG1979	alcohol dehydrogenase
WM48_RS16785	COG0656	L-ascorbic acid biosynthetic process
WM48_RS16795	COG4238	major outer membrane lipoprotein
WM48_RS16800	COG1032	radical SAM domain protein
WM48_RS16805	COG2186	Transcriptional regulator
WM48_RS16810	COG0246	Mannitol dehydrogenase
WM48_RS16815	COG1063	alcohol dehydrogenase
WM48_RS16820	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WM48_RS16840	COG2132	Multicopper oxidase
WM48_RS16845	COG0204	Acyl-transferase
WM48_RS16850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WM48_RS16855	COG4166	transmembrane transport
WM48_RS16860	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
WM48_RS16865	COG3111	PFAM Bacterial OB fold (BOF) protein
WM48_RS16870	COG0745	RESPONSE REGULATOR receiver
WM48_RS16875	COG0642	Histidine kinase
WM48_RS16895	COG2249	NAD(P)H dehydrogenase (quinone) activity
WM48_RS16900	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
WM48_RS16905	COG1737	Transcriptional regulator
WM48_RS16915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS16920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS16925	COG1120	ATPase activity
WM48_RS16930	COG4774	siderophore transport
WM48_RS16935	COG2211	Major facilitator Superfamily
WM48_RS16955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS16975	COG0187	DNA topoisomerase II activity
WM48_RS16980	COG3150	esterase
WM48_RS16985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WM48_RS16990	COG3151	Protein conserved in bacteria
WM48_RS16995	COG0494	nUDIX hydrolase
WM48_RS17000	COG1538	Outer membrane efflux protein
WM48_RS17015	COG0754	glutathionylspermidine amidase activity
WM48_RS17025	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WM48_RS17035	COG3384	dioxygenase
WM48_RS17065	COG1585	Membrane protein implicated in regulation of membrane protease activity
WM48_RS17070	COG2268	Band 7 protein
WM48_RS17085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WM48_RS17090	COG3025	triphosphatase activity
WM48_RS17100	COG4991	sh3 domain protein
WM48_RS17115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WM48_RS17135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WM48_RS17140	COG0471	metal ion transport
WM48_RS17150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WM48_RS17155	COG0358	DNA primase activity
WM48_RS17160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WM48_RS17175	COG2375	cellular response to nickel ion
WM48_RS17180	COG1695	Transcriptional regulator
WM48_RS17185	COG0840	transmembrane signaling receptor activity
WM48_RS17195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WM48_RS17200	COG1609	Transcriptional regulator
WM48_RS17205	COG3250	beta-galactosidase activity
WM48_RS17210	COG2731	YhcH YjgK YiaL family protein
WM48_RS17215	COG0531	amino acid
WM48_RS17225	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
WM48_RS17225	COG3408	Glycogen debranching enzyme
WM48_RS17230	COG0446	pyridine nucleotide-disulphide oxidoreductase
WM48_RS17230	COG1902	pentaerythritol trinitrate reductase activity
WM48_RS17235	COG5499	transcription regulator containing HTH domain
WM48_RS17240	COG4680	protein conserved in bacteria
WM48_RS17250	COG1451	nucleotide metabolic process
WM48_RS17255	COG2949	membrane
WM48_RS17260	COG0673	inositol 2-dehydrogenase activity
WM48_RS17265	COG0861	Integral membrane protein TerC family
WM48_RS17280	COG2721	sulfolactate sulfo-lyase activity
WM48_RS17290	COG2271	Major facilitator Superfamily
WM48_RS17315	COG2186	Transcriptional regulator
WM48_RS17320	COG0586	Pfam SNARE associated Golgi protein
WM48_RS17330	COG1422	Protein of unknown function (DUF1090)
WM48_RS17335	COG4575	ribosome binding
WM48_RS17340	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
WM48_RS17350	COG2259	Doxx family
WM48_RS17355	COG0435	Glutathione S-transferase
WM48_RS17360	COG3152	Membrane
WM48_RS17365	COG0583	DNA-binding transcription factor activity
WM48_RS17370	COG1741	Belongs to the pirin family
WM48_RS17385	COG0814	amino acid
WM48_RS17390	COG1760	l-serine dehydratase
WM48_RS17395	COG0251	oxidation-reduction process
WM48_RS17400	COG1882	Formate acetyltransferase
WM48_RS17405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WM48_RS17415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WM48_RS17420	COG0583	DNA-binding transcription factor activity
WM48_RS17435	COG1929	Belongs to the glycerate kinase type-1 family
WM48_RS17440	COG2084	Dehydrogenase
WM48_RS17450	COG2271	Major facilitator Superfamily
WM48_RS17455	COG2721	sulfolactate sulfo-lyase activity
WM48_RS17460	COG2002	toxin-antitoxin pair type II binding
WM48_RS17470	COG1349	DNA-binding transcription factor activity
WM48_RS17480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS17490	COG3716	PTS system mannose fructose sorbose family IID component
WM48_RS17495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS17500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WM48_RS17505	COG2222	sugar isomerase
WM48_RS17515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS17520	COG3715	PTS system
WM48_RS17525	COG3716	PTS system mannose fructose sorbose family IID component
WM48_RS17530	COG0363	glucosamine-6-phosphate deaminase activity
WM48_RS17535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WM48_RS17540	COG3107	peptidoglycan biosynthetic process
WM48_RS17555	COG2823	Periplasmic or secreted lipoprotein
WM48_RS17560	COG0701	Predicted permease
WM48_RS17565	COG0702	epimerase
WM48_RS17570	COG0693	protein deglycase activity
WM48_RS17585	COG3153	acetyltransferase
WM48_RS17590	COG3154	lipid carrier protein
WM48_RS17595	COG0826	peptidase U32
WM48_RS17600	COG0826	peptidase U32
WM48_RS17605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WM48_RS17610	COG0814	amino acid
WM48_RS17620	COG0513	Belongs to the DEAD box helicase family
WM48_RS17655	COG0195	Participates in both transcription termination and antitermination
WM48_RS17690	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WM48_RS17700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WM48_RS17705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WM48_RS17715	COG1534	Rna-binding protein
WM48_RS17720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WM48_RS17725	COG2027	D-alanyl-D-alanine carboxypeptidase
WM48_RS17735	COG0697	spore germination
WM48_RS17750	COG0142	geranyltranstransferase activity
WM48_RS17755	COG3423	Transcriptional regulator
WM48_RS17765	COG5007	Belongs to the BolA IbaG family
WM48_RS17770	COG3113	response to antibiotic
WM48_RS17775	COG2854	intermembrane phospholipid transfer
WM48_RS17780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WM48_RS17785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WM48_RS17790	COG1127	ABC transporter
WM48_RS17795	COG0530	calcium, potassium:sodium antiporter activity
WM48_RS17800	COG0517	IMP dehydrogenase activity
WM48_RS17800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WM48_RS17805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WM48_RS17810	COG3117	lipopolysaccharide transmembrane transporter activity
WM48_RS17815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WM48_RS17820	COG1137	ATPase activity
WM48_RS17825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WM48_RS17830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WM48_RS17845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS17850	COG0515	serine threonine protein kinase
WM48_RS17860	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WM48_RS17865	COG0784	Response regulator, receiver
WM48_RS17865	COG2198	Histidine kinase
WM48_RS17865	COG5002	protein histidine kinase activity
WM48_RS17870	COG1242	4 iron, 4 sulfur cluster binding
WM48_RS17875	COG0067	glutamate synthase
WM48_RS17875	COG0069	glutamate synthase activity
WM48_RS17875	COG0070	glutamate synthase
WM48_RS17880	COG0493	'glutamate synthase
WM48_RS17885	COG4804	nuclease activity
WM48_RS17890	COG2731	YhcH YjgK YiaL family protein
WM48_RS17920	COG2969	positive regulation of protein catabolic process
WM48_RS17925	COG0625	glutathione transferase activity
WM48_RS17940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WM48_RS17945	COG3105	Protein conserved in bacteria
WM48_RS17950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WM48_RS17955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WM48_RS17975	COG2732	(Barnase) inhibitor
WM48_RS17995	COG0583	DNA-binding transcription factor activity
WM48_RS18000	COG0312	modulator of DNA gyrase
WM48_RS18005	COG3164	Protein of unknown function
WM48_RS18010	COG1530	ribonuclease E activity
WM48_RS18020	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WM48_RS18025	COG1792	Involved in formation and maintenance of cell shape
WM48_RS18030	COG1077	Cell shape determining protein MreB Mrl
WM48_RS18040	COG2200	EAL domain
WM48_RS18040	COG2199	diguanylate cyclase activity
WM48_RS18045	COG0604	alcohol dehydrogenase
WM48_RS18060	COG0511	ligase activity, forming carbon-carbon bonds
WM48_RS18065	COG0439	Biotin carboxylase
WM48_RS18075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS18080	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM48_RS18085	COG1129	ABC transporter
WM48_RS18090	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS18100	COG1349	DNA-binding transcription factor activity
WM48_RS18110	COG3924	membrane
WM48_RS18115	COG4145	pantothenate transmembrane transporter activity
WM48_RS18125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WM48_RS18135	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WM48_RS18145	COG1309	transcriptional regulator
WM48_RS18150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS18155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM48_RS18175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WM48_RS18180	COG4597	amino acid ABC transporter
WM48_RS18185	COG0765	amino acid transport
WM48_RS18190	COG1126	abc transporter atp-binding protein
WM48_RS18230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WM48_RS18250	COG0551	DNA topoisomerase type I activity
WM48_RS18260	COG0758	DNA mediated transformation
WM48_RS18280	COG0569	domain protein
WM48_RS18290	COG3036	rescue of stalled ribosome
WM48_RS18295	COG0789	Transcriptional regulator
WM48_RS18335	COG0201	protein transport
WM48_RS18425	COG0089	rRNA binding
WM48_RS18450	COG3409	Peptidoglycan-binding domain 1 protein
WM48_RS18450	COG3267	Type II secretory pathway component ExeA
WM48_RS18455	COG3031	protein transport across the cell outer membrane
WM48_RS18460	COG1450	Type ii and iii secretion system protein
WM48_RS18465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WM48_RS18470	COG1459	type II secretion system
WM48_RS18475	COG2165	general secretion pathway protein
WM48_RS18480	COG2165	general secretion pathway protein
WM48_RS18485	COG2165	general secretion pathway protein
WM48_RS18490	COG4795	General secretion pathway protein
WM48_RS18495	COG3156	type II secretion system protein K
WM48_RS18500	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WM48_RS18505	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WM48_RS18510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WM48_RS18515	COG2193	ferroxidase activity
WM48_RS18520	COG2906	2 iron, 2 sulfur cluster binding
WM48_RS18525	COG3979	chitinase
WM48_RS18565	COG2964	Protein conserved in bacteria
WM48_RS18570	COG0545	Peptidyl-prolyl cis-trans isomerase
WM48_RS18580	COG1047	Peptidyl-prolyl cis-trans
WM48_RS18585	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WM48_RS18600	COG0488	(ABC) transporter
WM48_RS18605	COG0429	hydrolase of the alpha beta-hydrolase fold
WM48_RS18615	COG3954	Phosphoribulokinase
WM48_RS18620	COG1765	OsmC-like protein
WM48_RS18630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WM48_RS18635	COG1289	transmembrane transporter activity
WM48_RS18640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WM48_RS18645	COG0512	Glutamine amidotransferase of anthranilate synthase
WM48_RS18650	COG2184	nucleotidyltransferase activity
WM48_RS18660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WM48_RS18670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WM48_RS18675	COG2146	nitrite reductase [NAD(P)H] activity
WM48_RS18680	COG2116	formate transmembrane transporter activity
WM48_RS18695	COG0626	cystathionine gamma-synthase activity
WM48_RS18710	COG1735	metal-dependent hydrolase with the TIM-barrel fold
WM48_RS18715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
WM48_RS18720	COG3457	Alanine racemase
WM48_RS18730	COG2188	Transcriptional regulator
WM48_RS18735	COG0180	Tryptophanyl-tRNA synthetase
WM48_RS18745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WM48_RS18750	COG0338	D12 class N6 adenine-specific DNA methyltransferase
WM48_RS18755	COG3266	domain, Protein
WM48_RS18770	COG4796	Type ii and iii secretion system protein
WM48_RS18785	COG3166	PFAM Fimbrial assembly family protein
WM48_RS18790	COG4972	Pilus assembly protein
WM48_RS18795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WM48_RS18800	COG0494	nUDIX hydrolase
WM48_RS18810	COG1011	Hydrolase
WM48_RS18815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WM48_RS18850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WM48_RS18855	COG2183	response to ionizing radiation
WM48_RS18860	COG1918	ferrous iron import across plasma membrane
WM48_RS18865	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WM48_RS18875	COG5464	transposase or invertase
WM48_RS18895	COG2610	gluconate transmembrane transporter activity
WM48_RS18900	COG1640	4-alpha-glucanotransferase
WM48_RS18905	COG0058	SHG alpha-glucan phosphorylase activity
WM48_RS18920	COG1690	Belongs to the RtcB family
WM48_RS18925	COG4650	regulator
WM48_RS18930	COG1349	DNA-binding transcription factor activity
WM48_RS18945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WM48_RS18985	COG3188	usher protein
WM48_RS18990	COG3121	Chaperone
WM48_RS19000	COG0058	SHG alpha-glucan phosphorylase activity
WM48_RS19025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WM48_RS19030	COG2095	MarC family integral membrane protein
WM48_RS19040	COG0514	ATP-dependent DNA helicase (RecQ)
WM48_RS19045	COG2610	gluconate transmembrane transporter activity
WM48_RS19050	COG3265	gluconokinase activity
WM48_RS19055	COG1609	Transcriptional regulator
WM48_RS19060	COG1741	Belongs to the pirin family
WM48_RS19065	COG0673	inositol 2-dehydrogenase activity
WM48_RS19075	COG1247	-acetyltransferase
WM48_RS19080	COG3157	Type VI secretion system effector, Hcp
WM48_RS19095	COG0405	Gamma-glutamyltransferase
WM48_RS19105	COG0584	glycerophosphoryl diester phosphodiesterase
WM48_RS19135	COG0410	ABC transporter
WM48_RS19140	COG0411	ABC transporter
WM48_RS19145	COG4177	L-phenylalanine transmembrane transporter activity
WM48_RS19150	COG0559	Belongs to the binding-protein-dependent transport system permease family
WM48_RS19155	COG0683	leucine binding
WM48_RS19160	COG0456	acetyltransferase
WM48_RS19170	COG0683	leucine binding
WM48_RS19175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WM48_RS19180	COG2177	Part of the ABC transporter FtsEX involved in
WM48_RS19185	COG2884	Cell division ATP-binding protein ftsE
WM48_RS19190	COG0552	protein localization to endoplasmic reticulum
WM48_RS19195	COG0742	ribosomal rna small subunit methyltransferase
WM48_RS19200	COG3776	membrane
WM48_RS19210	COG3714	YhhN family
WM48_RS19225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WM48_RS19235	COG0477	Major facilitator Superfamily
WM48_RS19240	COG0628	permease
WM48_RS19245	COG2091	lysine biosynthetic process via aminoadipic acid
WM48_RS19250	COG0747	negative chemotaxis
WM48_RS19255	COG0601	transmembrane transport
WM48_RS19260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WM48_RS19280	COG0842	Transport permease protein
WM48_RS19285	COG1129	ABC transporter
WM48_RS19285	COG0842	Transport permease protein
WM48_RS19290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS19300	COG2081	HI0933 family
WM48_RS19305	COG0306	phosphate transporter
WM48_RS19315	COG0589	response to stress
WM48_RS19320	COG3104	oligopeptide transport
WM48_RS19330	COG0339	signal peptide processing
WM48_RS19335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WM48_RS19340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WM48_RS19355	COG1393	Belongs to the ArsC family
WM48_RS19360	COG3065	identical protein binding
WM48_RS19365	COG2197	response regulator
WM48_RS19370	COG3720	iron ion transport
WM48_RS19375	COG4771	TonB-dependent receptor
WM48_RS19395	COG3721	Heme iron utilization protein
WM48_RS19405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WM48_RS19415	COG1285	pathogenesis
WM48_RS19430	COG3247	response to pH
WM48_RS19435	COG2771	luxR family
WM48_RS19445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WM48_RS19450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WM48_RS19455	COG2207	Transcriptional regulator
WM48_RS19465	COG0076	glutamate decarboxylase activity
WM48_RS19470	COG1858	cytochrome C peroxidase
WM48_RS19480	COG2197	response regulator
WM48_RS19485	COG0583	DNA-binding transcription factor activity
WM48_RS19490	COG1295	ribonuclease BN
WM48_RS19495	COG0477	Major facilitator Superfamily
WM48_RS19500	COG2982	Protein involved in outer membrane biogenesis
WM48_RS19505	COG2200	EAL domain
WM48_RS19515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS19520	COG0612	Peptidase, M16
WM48_RS19530	COG2199	diguanylate cyclase activity
WM48_RS19530	COG2200	EAL domain
WM48_RS19535	COG3118	belongs to the thioredoxin family
WM48_RS19535	COG0457	Tetratricopeptide repeat
WM48_RS19540	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WM48_RS19545	COG1215	transferase activity, transferring glycosyl groups
WM48_RS19550	COG1215	transferase activity, transferring glycosyl groups
WM48_RS19590	COG0814	amino acid
WM48_RS19595	COG4608	Belongs to the ABC transporter superfamily
WM48_RS19600	COG0444	Belongs to the ABC transporter superfamily
WM48_RS19605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WM48_RS19610	COG0601	transmembrane transport
WM48_RS19620	COG0747	negative chemotaxis
WM48_RS19635	COG2194	sulfuric ester hydrolase activity
WM48_RS19640	COG2223	nitrite transmembrane transporter activity
WM48_RS19645	COG5571	outer membrane autotransporter
WM48_RS19650	COG2818	Glycosylase
WM48_RS19655	COG0456	acetyltransferase
WM48_RS19660	COG0243	molybdopterin cofactor binding
WM48_RS19665	COG2885	chlorophyll binding
WM48_RS19680	COG2944	sequence-specific DNA binding
WM48_RS19685	COG1278	Cold shock
WM48_RS19710	COG3274	enterobacterial common antigen metabolic process
WM48_RS19715	COG4682	membrane
WM48_RS19720	COG4682	membrane
WM48_RS19725	COG1070	Carbohydrate kinase
WM48_RS19735	COG4213	ABC transporter substrate-binding protein
WM48_RS19745	COG4214	carbohydrate transport
WM48_RS19750	COG1609	Transcriptional regulator
WM48_RS19750	COG2207	Transcriptional regulator
WM48_RS19755	COG2992	FlgJ-related protein
WM48_RS19760	COG0366	Alpha amylase catalytic
WM48_RS19765	COG3977	Valine--pyruvate aminotransferase
WM48_RS19775	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WM48_RS19780	COG1414	Transcriptional regulator
WM48_RS19790	COG2731	YhcH YjgK YiaL family protein
WM48_RS19800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WM48_RS19805	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WM48_RS19810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WM48_RS19815	COG1070	Carbohydrate kinase
WM48_RS19820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
WM48_RS19825	COG3623	hexulose-6-phosphate isomerase
WM48_RS19830	COG0235	Class ii aldolase
WM48_RS19835	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS19840	COG1454	alcohol dehydrogenase
WM48_RS19845	COG3276	selenocysteine insertion sequence binding
WM48_RS19855	COG0625	glutathione transferase activity
WM48_RS19860	COG1566	PFAM secretion protein HlyD family protein
WM48_RS19870	COG2213	PTS system mannitol-specific
WM48_RS19870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS19880	COG3722	fumarate hydratase activity
WM48_RS19900	COG5295	Hep Hag repeat protein
WM48_RS19905	COG1620	l-lactate permease
WM48_RS19910	COG2186	Transcriptional regulator
WM48_RS19920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WM48_RS19925	COG1045	serine acetyltransferase
WM48_RS19940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WM48_RS19945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WM48_RS19955	COG4942	peptidase
WM48_RS19960	COG2861	carbohydrate metabolic process
WM48_RS19965	COG1216	Glycosyl transferase, family 2
WM48_RS19975	COG0156	8-amino-7-oxononanoate synthase activity
WM48_RS19985	COG0859	PFAM glycosyl transferase family 9
WM48_RS19990	COG0859	PFAM glycosyl transferase family 9
WM48_RS19995	COG3307	-O-antigen
WM48_RS20000	COG1216	Glycosyl transferase, family 2
WM48_RS20005	COG1442	glycosyl transferase family 8
WM48_RS20010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WM48_RS20025	COG0515	serine threonine protein kinase
WM48_RS20030	COG0438	transferase activity, transferring glycosyl groups
WM48_RS20035	COG0859	PFAM glycosyl transferase family 9
WM48_RS20040	COG1519	Transferase
WM48_RS20070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WM48_RS20095	COG1561	YicC-like family, N-terminal region
WM48_RS20100	COG3645	SOS response
WM48_RS20105	COG2860	membrane
WM48_RS20115	COG0194	GDP metabolic process
WM48_RS20125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WM48_RS20130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WM48_RS20135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WM48_RS20140	COG0786	glutamate:sodium symporter activity
WM48_RS20145	COG2233	PERMEase
WM48_RS20150	COG2982	Protein involved in outer membrane biogenesis
WM48_RS20160	COG1940	carbohydrate kinase activity
WM48_RS20165	COG0191	fructose-bisphosphate aldolase activity
WM48_RS20175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS20175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS20180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS20185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS20185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS20185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS20190	COG3711	transcriptional antiterminator
WM48_RS20195	COG1501	Belongs to the glycosyl hydrolase 31 family
WM48_RS20200	COG2211	Major facilitator Superfamily
WM48_RS20210	COG0582	viral genome integration into host DNA
WM48_RS20290	COG0697	spore germination
WM48_RS20295	COG1464	Belongs to the NlpA lipoprotein family
WM48_RS20320	COG2252	PERMEase
WM48_RS20330	COG2271	Major facilitator Superfamily
WM48_RS20335	COG2271	Major facilitator Superfamily
WM48_RS20340	COG3851	Histidine kinase
WM48_RS20345	COG2197	response regulator
WM48_RS20360	COG0440	acetolactate synthase activity
WM48_RS20365	COG0028	Belongs to the TPP enzyme family
WM48_RS20375	COG2814	Major facilitator Superfamily
WM48_RS20380	COG0641	radical SAM
WM48_RS20390	COG2149	membrane
WM48_RS20395	COG3119	arylsulfatase activity
WM48_RS20400	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WM48_RS20405	COG2207	Transcriptional regulator
WM48_RS20425	COG5645	(Lipo)protein
WM48_RS20430	COG0823	Involved in the tonB-independent uptake of proteins
WM48_RS20440	COG2271	Major facilitator Superfamily
WM48_RS20450	COG0800	Aldolase
WM48_RS20455	COG3734	2-keto-3-deoxy-galactonokinase
WM48_RS20460	COG2186	Transcriptional regulator
WM48_RS20470	COG0561	phosphatase activity
WM48_RS20475	COG3753	Protein conserved in bacteria
WM48_RS20485	COG0187	DNA topoisomerase II activity
WM48_RS20495	COG0592	DNA-directed DNA polymerase activity
WM48_RS20540	COG0814	amino acid
WM48_RS20550	COG0583	DNA-binding transcription factor activity
WM48_RS20555	COG2091	lysine biosynthetic process via aminoadipic acid
WM48_RS20560	COG0431	NADPH-dependent FMN reductase
WM48_RS20565	COG2252	PERMEase
WM48_RS20570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WM48_RS20580	COG0363	glucosamine-6-phosphate deaminase activity
WM48_RS20595	COG2723	6-phospho-beta-galactosidase activity
WM48_RS20600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS20600	COG2190	(PTS) system
WM48_RS20600	COG1263	PTS System
WM48_RS20605	COG3711	transcriptional antiterminator
WM48_RS20610	COG0704	Plays a role in the regulation of phosphate uptake
WM48_RS20615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WM48_RS20620	COG0581	inorganic phosphate transmembrane transporter activity
WM48_RS20625	COG0573	inorganic phosphate transmembrane transporter activity
WM48_RS20630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WM48_RS20685	COG3312	ion transport
WM48_RS20700	COG0716	FMN binding
WM48_RS20705	COG1522	sequence-specific DNA binding
WM48_RS20735	COG1129	ABC transporter
WM48_RS20740	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM48_RS20745	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS20750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS20755	COG1609	Transcriptional regulator
WM48_RS20760	COG0477	Major facilitator Superfamily
WM48_RS20765	COG2186	Transcriptional regulator
WM48_RS20805	COG3085	chromosome segregation
WM48_RS20810	COG0606	chelatase, subunit chli
WM48_RS20825	COG3978	acetolactate synthase activity
WM48_RS20830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WM48_RS20840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WM48_RS20845	COG0583	DNA-binding transcription factor activity
WM48_RS20855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WM48_RS20860	COG0210	DNA helicase
WM48_RS20875	COG3118	belongs to the thioredoxin family
WM48_RS20885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WM48_RS20895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WM48_RS20900	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
WM48_RS20905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
WM48_RS20910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WM48_RS20915	COG1088	dTDP-glucose 4,6-dehydratase activity
WM48_RS20920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WM48_RS20925	COG0456	acetyltransferase
WM48_RS20930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WM48_RS20935	COG2244	polysaccharide biosynthetic process
WM48_RS20955	COG1113	amino acid transport
WM48_RS20980	COG0641	radical SAM
WM48_RS20985	COG3119	arylsulfatase activity
WM48_RS20990	COG3071	HemY protein
WM48_RS20995	COG2959	enzyme of heme biosynthesis
WM48_RS21000	COG1587	Uroporphyrinogen-III synthase
WM48_RS21005	COG0181	hydroxymethylbilane synthase activity
WM48_RS21010	COG3072	Adenylate cyclase
WM48_RS21020	COG5567	small periplasmic lipoprotein
WM48_RS21030	COG3159	Protein conserved in bacteria
WM48_RS21040	COG1011	Hydrolase
WM48_RS21045	COG0210	DNA helicase
WM48_RS21050	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
WM48_RS21055	COG3698	Phosphodiester glycosidase
WM48_RS21065	COG0598	Magnesium transport protein CorA
WM48_RS21080	COG2962	Rard protein
WM48_RS21085	COG2050	protein possibly involved in aromatic compounds catabolism
WM48_RS21090	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
WM48_RS21095	COG0514	ATP-dependent DNA helicase (RecQ)
WM48_RS21100	COG1280	lysine exporter protein (LysE YggA)
WM48_RS21105	COG1280	lysine exporter protein (LysE YggA)
WM48_RS21110	COG2267	carboxylic ester hydrolase activity
WM48_RS21115	COG0561	phosphatase activity
WM48_RS21120	COG0697	spore germination
WM48_RS21125	COG0583	DNA-binding transcription factor activity
WM48_RS21145	COG3157	Type VI secretion system effector, Hcp
WM48_RS21155	COG2190	(PTS) system
WM48_RS21155	COG1263	PTS System
WM48_RS21155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS21160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WM48_RS21165	COG1737	Transcriptional regulator
WM48_RS21170	COG0583	DNA-binding transcription factor activity
WM48_RS21175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WM48_RS21185	COG0549	Belongs to the carbamate kinase family
WM48_RS21190	COG1304	FMN binding
WM48_RS21195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM48_RS21205	COG1335	isochorismatase
WM48_RS21215	COG0412	Dienelactone hydrolase
WM48_RS21220	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
WM48_RS21240	COG0800	Aldolase
WM48_RS21245	COG3734	2-keto-3-deoxy-galactonokinase
WM48_RS21250	COG1414	Transcriptional regulator
WM48_RS21255	COG1322	Protein conserved in bacteria
WM48_RS21265	COG3165	ubiquinone biosynthetic process from chorismate
WM48_RS21275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WM48_RS21285	COG0805	protein transport
WM48_RS21300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WM48_RS21305	COG0543	2 iron, 2 sulfur cluster binding
WM48_RS21325	COG1739	Uncharacterized protein family UPF0029
WM48_RS21330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WM48_RS21335	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
WM48_RS21365	COG1763	Mo-molybdopterin cofactor biosynthetic process
WM48_RS21370	COG0746	molybdenum cofactor guanylyltransferase activity
WM48_RS21375	COG3084	Protein conserved in bacteria
WM48_RS21380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WM48_RS21385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WM48_RS21390	COG5339	Protein conserved in bacteria
WM48_RS21395	COG0204	Acyl-transferase
WM48_RS21405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WM48_RS21405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WM48_RS21420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WM48_RS21430	COG2204	response regulator
WM48_RS21435	COG3852	Histidine kinase
WM48_RS21440	COG0174	glutamine synthetase
WM48_RS21450	COG1217	gtp-binding protein TYPA
WM48_RS21455	COG2188	Transcriptional regulator
WM48_RS21460	COG1082	Xylose isomerase domain protein TIM barrel
WM48_RS21465	COG2271	Major facilitator Superfamily
WM48_RS21470	COG1349	DNA-binding transcription factor activity
WM48_RS21475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WM48_RS21480	COG2084	Dehydrogenase
WM48_RS21485	COG3684	Belongs to the aldolase LacD family
WM48_RS21490	COG1063	alcohol dehydrogenase
WM48_RS21500	COG0477	Major facilitator Superfamily
WM48_RS21510	COG1011	Hydrolase
WM48_RS21535	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WM48_RS21560	COG2864	formate dehydrogenase
WM48_RS21565	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS21570	COG3383	formate dehydrogenase (NAD+) activity
WM48_RS21570	COG0243	molybdopterin cofactor binding
WM48_RS21575	COG3383	formate dehydrogenase (NAD+) activity
WM48_RS21575	COG0243	molybdopterin cofactor binding
WM48_RS21635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WM48_RS21650	COG2258	MOSC domain
WM48_RS21655	COG2205	protein histidine kinase activity
WM48_RS21660	COG0745	RESPONSE REGULATOR receiver
WM48_RS21665	COG3678	ATP-independent chaperone mediated protein folding
WM48_RS21680	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WM48_RS21700	COG3152	Membrane
WM48_RS21705	COG3691	Protein conserved in bacteria
WM48_RS21710	COG0589	response to stress
WM48_RS21720	COG1494	fructose-1,6-bisphosphatase
WM48_RS21730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WM48_RS21745	COG1575	Belongs to the MenA family. Type 1 subfamily
WM48_RS21760	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WM48_RS21765	COG1609	Transcriptional regulator
WM48_RS21770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WM48_RS21780	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
WM48_RS21790	COG0626	cystathionine gamma-synthase activity
WM48_RS21795	COG0460	homoserine dehydrogenase
WM48_RS21795	COG0527	aspartate kinase activity
WM48_RS21810	COG0737	Belongs to the 5'-nucleotidase family
WM48_RS21820	COG0737	Belongs to the 5'-nucleotidase family
WM48_RS21825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WM48_RS21835	COG0697	spore germination
WM48_RS21840	COG3738	Protein conserved in bacteria
WM48_RS21845	COG0371	Dehydrogenase
WM48_RS21850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WM48_RS21855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS21855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WM48_RS21855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM48_RS21860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS21865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS21870	COG1882	Formate acetyltransferase
WM48_RS21875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM48_RS21880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WM48_RS21885	COG2207	Transcriptional regulator
WM48_RS21890	COG2194	sulfuric ester hydrolase activity
WM48_RS21905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WM48_RS21910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WM48_RS21920	COG4948	Mandelate Racemase Muconate Lactonizing
WM48_RS21925	COG2271	Major facilitator Superfamily
WM48_RS21930	COG0583	DNA-binding transcription factor activity
WM48_RS21940	COG1473	amidohydrolase
WM48_RS21945	COG0477	Major facilitator Superfamily
WM48_RS21995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WM48_RS22000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
WM48_RS22000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
WM48_RS22040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WM48_RS22045	COG0250	Participates in transcription elongation, termination and antitermination
WM48_RS22080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WM48_RS22090	COG2104	thiamine diphosphate biosynthetic process
WM48_RS22095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WM48_RS22130	COG3068	Protein conserved in bacteria
WM48_RS22145	COG3678	ATP-independent chaperone mediated protein folding
WM48_RS22150	COG4191	Histidine kinase
WM48_RS22155	COG2204	response regulator
WM48_RS22160	COG0151	Belongs to the GarS family
WM48_RS22205	COG0456	acetyltransferase
WM48_RS22215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WM48_RS22220	COG2224	Isocitrate lyase
WM48_RS22230	COG1414	Transcriptional regulator
WM48_RS22235	COG0646	methionine synthase
WM48_RS22235	COG1410	methionine synthase
WM48_RS22250	COG1283	sodium-dependent phosphate transmembrane transporter activity
WM48_RS22300	COG1187	pseudouridine synthase activity
WM48_RS22310	COG0527	aspartate kinase activity
WM48_RS22335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WM48_RS22355	COG3833	ABC-type maltose transport systems, permease component
WM48_RS22360	COG1175	transmembrane transport
WM48_RS22365	COG2182	Extracellular solute-binding protein
WM48_RS22405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WM48_RS22415	COG0534	Mate efflux family protein
WM48_RS22420	COG3237	CsbD-like
WM48_RS22425	COG0735	belongs to the Fur family
WM48_RS22430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WM48_RS22440	COG0604	alcohol dehydrogenase
WM48_RS22445	COG0305	Participates in initiation and elongation during chromosome replication
WM48_RS22455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WM48_RS22460	COG3201	nicotinamide mononucleotide transporter
WM48_RS22470	COG1448	Aminotransferase
WM48_RS22475	COG0567	Dehydrogenase, E1 component
WM48_RS22485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WM48_RS22495	COG0045	succinate-CoA ligase (ADP-forming) activity
WM48_RS22500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WM48_RS22505	COG0471	metal ion transport
WM48_RS22510	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
WM48_RS22515	COG2204	response regulator
WM48_RS22525	COG3700	Belongs to the class B bacterial acid phosphatase family
WM48_RS22530	COG0432	Pfam Uncharacterised protein family UPF0047
WM48_RS22535	COG2315	Protein conserved in bacteria
WM48_RS22540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WM48_RS22545	COG0629	single-stranded DNA binding
WM48_RS22555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
WM48_RS22560	COG2207	Transcriptional regulator
WM48_RS22565	COG0789	Transcriptional regulator
WM48_RS22570	COG2252	PERMEase
WM48_RS22575	COG0025	NhaP-type Na H and K H
WM48_RS22585	COG1380	Effector of murein hydrolase LrgA
WM48_RS22590	COG1346	cytolysis
WM48_RS22600	COG3162	membrane
WM48_RS22605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WM48_RS22615	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
WM48_RS22620	COG0437	4 iron, 4 sulfur cluster binding
WM48_RS22625	COG3301	Polysulphide reductase, NrfD
WM48_RS22630	COG1138	Cytochrome C-type biogenesis protein
WM48_RS22635	COG3088	subunit of a heme lyase
WM48_RS22640	COG4235	cytochrome complex assembly
WM48_RS22645	COG1301	dicarboxylic acid transport
WM48_RS22660	COG2801	Transposase and inactivated derivatives
WM48_RS22665	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
WM48_RS22670	COG4608	Belongs to the ABC transporter superfamily
WM48_RS22675	COG0444	Belongs to the ABC transporter superfamily
WM48_RS22680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WM48_RS22685	COG0601	transmembrane transport
WM48_RS22695	COG3383	formate dehydrogenase (NAD+) activity
WM48_RS22700	COG3383	formate dehydrogenase (NAD+) activity
WM48_RS22710	COG1289	transmembrane transporter activity
WM48_RS22715	COG1566	PFAM secretion protein HlyD family protein
WM48_RS22725	COG2015	COG2015, Alkyl sulfatase and related hydrolases
WM48_RS22730	COG1940	carbohydrate kinase activity
WM48_RS22735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WM48_RS22740	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM48_RS22745	COG1129	ABC transporter
WM48_RS22750	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS22755	COG1737	Transcriptional regulator
WM48_RS22760	COG0698	ribose 5-phosphate isomerase
WM48_RS22770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WM48_RS22775	COG0456	acetyltransferase
WM48_RS22785	COG3454	Phosphonate metabolism
WM48_RS22790	COG4778	phosphonate C-P lyase system protein PhnL
WM48_RS22795	COG4107	phosphonate C-P lyase system protein PhnK
WM48_RS22800	COG3627	carbon phosphorus lyase activity
WM48_RS22805	COG3626	phosphonate metabolism
WM48_RS22810	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
WM48_RS22815	COG3624	Phosphonate C-P lyase system protein PhnG
WM48_RS22820	COG2188	Transcriptional regulator
WM48_RS22825	COG3639	organic phosphonate transmembrane transporter activity
WM48_RS22830	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
WM48_RS22840	COG2764	glyoxalase bleomycin resistance protein dioxygenase
WM48_RS22845	COG2824	Alkylphosphonate utilization operon protein PhnA
WM48_RS22860	COG0477	Major facilitator Superfamily
WM48_RS22870	COG0642	Histidine kinase
WM48_RS22875	COG0745	RESPONSE REGULATOR receiver
WM48_RS22880	COG2194	sulfuric ester hydrolase activity
WM48_RS22885	COG0531	amino acid
WM48_RS22890	COG2207	Transcriptional regulator
WM48_RS22895	COG1982	Orn Lys Arg decarboxylase major
WM48_RS22900	COG2169	Transcriptional regulator
WM48_RS22910	COG1486	melibiose metabolic process
WM48_RS22915	COG3647	Membrane
WM48_RS22920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WM48_RS22920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WM48_RS22925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WM48_RS22935	COG4565	transcriptional regulatory protein
WM48_RS22940	COG3290	protein histidine kinase activity
WM48_RS22945	COG3592	Divergent 4Fe-4S mono-cluster
WM48_RS22950	COG2388	GCN5-related N-acetyl-transferase
WM48_RS22965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WM48_RS22970	COG3104	oligopeptide transport
WM48_RS22975	COG1982	Orn Lys Arg decarboxylase major
WM48_RS22980	COG0531	amino acid
WM48_RS22985	COG3710	Transcriptional regulator
WM48_RS23000	COG1309	transcriptional regulator
WM48_RS23015	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WM48_RS23020	COG1027	Aspartate ammonia-lyase
WM48_RS23025	COG3030	protein affecting phage T7 exclusion by the F plasmid
WM48_RS23030	COG0531	amino acid
WM48_RS23055	COG1509	lysine 2,3-aminomutase activity
WM48_RS23065	COG5510	response to toxic substance
WM48_RS23070	COG5510	response to toxic substance
WM48_RS23075	COG2076	Multidrug Resistance protein
WM48_RS23080	COG3040	lipid binding
WM48_RS23085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WM48_RS23100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WM48_RS23105	COG1053	succinate dehydrogenase
WM48_RS23115	COG0531	amino acid
WM48_RS23120	COG3264	Mechanosensitive ion channel
WM48_RS23120	COG1511	domain protein
WM48_RS23155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WM48_RS23160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WM48_RS23160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WM48_RS23165	COG0802	atpase or kinase
WM48_RS23170	COG0860	N-Acetylmuramoyl-L-alanine amidase
WM48_RS23190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WM48_RS23195	COG0330	HflC and HflK could
WM48_RS23200	COG0330	HflC and HflK could
WM48_RS23205	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WM48_RS23220	COG0557	exoribonuclease II activity
WM48_RS23225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WM48_RS23230	COG3789	protein conserved in bacteria
WM48_RS23235	COG1842	Phage shock protein A
WM48_RS23245	COG3766	membrane
WM48_RS23250	COG5463	Belongs to the UPF0441 family
WM48_RS23255	COG0754	glutathionylspermidine amidase activity
WM48_RS23260	COG1960	acyl-CoA dehydrogenase activity
WM48_RS23270	COG3650	response to hydrogen peroxide
WM48_RS23275	COG1073	alpha beta
WM48_RS23290	COG3037	sugar-specific permease SgaT UlaA
WM48_RS23295	COG3414	Phosphotransferase system galactitol-specific IIB component
WM48_RS23340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WM48_RS23360	COG2271	Major facilitator Superfamily
WM48_RS23365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WM48_RS23370	COG4670	ketone body catabolic process
WM48_RS23375	COG1024	Enoyl-CoA hydratase
WM48_RS23390	COG1309	transcriptional regulator
WM48_RS23395	COG3061	Opacity-associated protein A
WM48_RS23400	COG0545	Peptidyl-prolyl cis-trans isomerase
WM48_RS23405	COG1113	amino acid transport
WM48_RS23415	COG0697	spore germination
WM48_RS23420	COG0702	epimerase
WM48_RS23425	COG1733	regulation of RNA biosynthetic process
WM48_RS23430	COG0737	Belongs to the 5'-nucleotidase family
WM48_RS23435	COG1218	3'(2'),5'-bisphosphate nucleotidase
WM48_RS23440	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WM48_RS23450	COG1253	flavin adenine dinucleotide binding
WM48_RS23465	COG0729	surface antigen
WM48_RS23470	COG2911	Protein conserved in bacteria
WM48_RS23475	COG2105	PFAM AIG2 family protein
WM48_RS23480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WM48_RS23485	COG1879	ABC-type sugar transport system periplasmic component
WM48_RS23490	COG1129	ABC transporter
WM48_RS23495	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM48_RS23500	COG1172	Belongs to the binding-protein-dependent transport system permease family
WM48_RS23510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WM48_RS23520	COG0312	modulator of DNA gyrase
WM48_RS23525	COG3783	Cytochrome b(562)
WM48_RS23530	COG0602	queuosine metabolic process
WM48_RS23535	COG1328	CTP reductase activity
WM48_RS23545	COG0366	Alpha amylase catalytic
WM48_RS23550	COG1263	PTS System
WM48_RS23550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WM48_RS23555	COG1609	Transcriptional regulator
WM48_RS23560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WM48_RS23565	COG0251	oxidation-reduction process
WM48_RS23585	COG1438	arginine binding
WM48_RS23590	COG1288	antiporter activity
WM48_RS23595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WM48_RS23600	COG0549	Belongs to the carbamate kinase family
WM48_RS23610	COG2731	YhcH YjgK YiaL family protein
WM48_RS23615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WM48_RS23620	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
WM48_RS23625	COG0456	acetyltransferase
WM48_RS23635	COG0525	valine-tRNA ligase activity
WM48_RS23640	COG2927	DNA polymerase III (CHI subunit)
WM48_RS23650	COG0795	lipopolysaccharide-transporting ATPase activity
WM48_RS23655	COG0795	lipopolysaccharide-transporting ATPase activity
WM48_RS23660	COG0433	COG0433 Predicted ATPase
WM48_RS23665	COG1609	Transcriptional regulator
WM48_RS23670	COG2610	gluconate transmembrane transporter activity
WM48_RS23675	COG1028	Short-chain dehydrogenase reductase Sdr
WM48_RS23680	COG1063	alcohol dehydrogenase
WM48_RS23685	COG3265	gluconokinase activity
WM48_RS23690	COG1064	alcohol dehydrogenase
WM48_RS23700	COG0582	viral genome integration into host DNA
WM48_RS23705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WM48_RS23705	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
WM48_RS23710	COG2194	sulfuric ester hydrolase activity
WM48_RS23835	COG2259	Doxx family
WM48_RS23840	COG1304	FMN binding
WM48_RS23850	COG1309	transcriptional regulator
WM48_RS23855	COG4372	Transposase
WM48_RS23860	COG3436	PFAM IS66 Orf2 family protein
WM48_RS23870	COG2801	Transposase and inactivated derivatives
WM48_RS23880	COG2801	Transposase and inactivated derivatives
WM48_RS23925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WM48_RS23930	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
WM48_RS23935	COG0745	RESPONSE REGULATOR receiver
WM48_RS23995	COG4372	Transposase
WM48_RS24050	COG2610	gluconate transmembrane transporter activity
WM48_RS24055	COG0583	DNA-binding transcription factor activity
WM48_RS24065	COG2076	Multidrug Resistance protein
WM48_RS24080	COG4869	propanediol catabolic process
WM48_RS24090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM48_RS24095	COG1882	Formate acetyltransferase
WM48_RS24100	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS24100	COG1454	alcohol dehydrogenase
WM48_RS24110	COG1454	alcohol dehydrogenase
WM48_RS24110	COG1012	belongs to the aldehyde dehydrogenase family
WM48_RS24165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WM48_RS24170	COG1757	Na H antiporter
WM48_RS24185	COG1757	Na H antiporter
WM48_RS24215	COG3596	GTP binding
WM48_RS24225	COG2378	regulation of single-species biofilm formation
WM48_RS24250	COG2003	Belongs to the UPF0758 family
WM48_RS24305	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WM48_RS24320	COG0582	viral genome integration into host DNA
WM48_RS24325	COG4974	Belongs to the 'phage' integrase family
WM48_RS24335	COG3539	Fimbrial protein
WM48_RS24340	COG3539	Fimbrial protein
WM48_RS24345	COG3121	Chaperone
WM48_RS24350	COG3188	usher protein
WM48_RS24355	COG3539	Fimbrial protein
WM48_RS24360	COG3539	Fimbrial protein
WM48_RS24365	COG3539	Fimbrial protein
WM48_RS24380	COG0246	Mannitol dehydrogenase
WM48_RS24390	COG2186	Transcriptional regulator
WM48_RS24405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WM48_RS24410	COG0583	DNA-binding transcription factor activity
WM48_RS24415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WM48_RS24420	COG0700	Nucleoside recognition
WM48_RS24425	COG3366	ferrous iron transmembrane transporter activity
WM48_RS24435	COG0477	Major facilitator Superfamily
WM48_RS24450	COG1924	4 iron, 4 sulfur cluster binding
WM48_RS24455	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
WM48_RS24460	COG2733	membrane
WM48_RS24500	COG0523	cobalamin synthesis protein
WM48_RS24505	COG2879	small protein
WM48_RS24510	COG1966	Carbon starvation protein
WM48_RS24520	COG0840	transmembrane signaling receptor activity
WM48_RS24525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WM48_RS24535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WM48_RS24540	COG0025	NhaP-type Na H and K H
WM48_RS24545	COG1802	Transcriptional regulator
WM48_RS24550	COG1063	alcohol dehydrogenase
WM48_RS24565	COG1484	DNA-dependent DNA replication
WM48_RS24580	COG2966	Psort location CytoplasmicMembrane, score
WM48_RS24585	COG2197	response regulator
WM48_RS24590	COG2197	response regulator
WM48_RS24595	COG4114	ferric iron reductase
WM48_RS24630	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
WM48_RS24635	COG0456	acetyltransferase
WM48_RS24640	COG1011	Hydrolase
WM48_RS24670	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
WM48_RS24675	COG5532	Uncharacterized conserved protein (DUF2303)
WM48_RS24720	COG1846	Transcriptional regulator
WM48_RS24730	COG4725	Belongs to the MT-A70-like family
WM48_RS24740	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
WM48_RS24750	COG1403	HNH endonuclease
WM48_RS24830	COG0740	serine-type endopeptidase activity
WM48_RS24900	COG5301	cellulose 1,4-beta-cellobiosidase activity
WM48_RS24930	COG2823	Periplasmic or secreted lipoprotein
WM48_RS24940	COG4667	esterase of the alpha-beta hydrolase superfamily
WM48_RS24945	COG0084	hydrolase, TatD family'
WM48_RS24950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WM48_RS24955	COG1328	CTP reductase activity
WM48_RS24995	COG3726	membrane protein affecting hemolysin expression
WM48_RS25000	COG0560	Phosphoserine phosphatase
WM48_RS25005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WM48_RS25010	COG1056	cytidyltransferase-related domain
WM48_RS25010	COG3172	ATPase kinase involved in NAD metabolism
WM48_RS25015	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WM48_RS25025	COG0488	(ABC) transporter
WM48_RS25030	COG0741	lytic transglycosylase activity
WM48_RS25050	COG3708	Transcriptional regulator
WM48_RS25050	COG2207	Transcriptional regulator
WM48_RS25055	COG3045	CreA protein
WM48_RS25060	COG0745	RESPONSE REGULATOR receiver
WM48_RS25065	COG2205	protein histidine kinase activity
WM48_RS25070	COG4452	Inner membrane protein CreD
WM48_RS25075	COG0745	RESPONSE REGULATOR receiver
WM48_RS25085	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WM48_RS25095	COG0527	aspartate kinase activity
WM48_RS25095	COG0460	homoserine dehydrogenase
WM48_RS25125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WM48_RS25255	COG0196	riboflavin kinase activity
WM48_RS25715	COG0772	Belongs to the SEDS family
WM48_RS25735	COG0527	aspartate kinase activity
WM48_RS25735	COG0460	homoserine dehydrogenase
WM48_RS25745	COG0527	aspartate kinase activity
WM48_RS25745	COG0460	homoserine dehydrogenase
WM48_RS26025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WM48_RS26135	COG0586	Pfam SNARE associated Golgi protein
WM48_RS26300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity