locus-tag class description HR071_RS00100 ENOG4108X9F tail fiber protein HR071_RS00125 ENOG4108WF3 methyltransferase HR071_RS00140 ENOG4105EIF outer membrane protein W HR071_RS00155 ENOG4105DK0 Indole-3-glycerol phosphate synthase HR071_RS00160 ENOG4108EFP Anthranilate synthase component II HR071_RS00165 ENOG4105CRQ synthase (Component I) HR071_RS00175 ENOG4105DB7 PHP domain protein HR071_RS00180 ENOG4107RTD sua5 ycio yrdc ywlc family protein HR071_RS00185 ENOG4105EG3 transmembrane signal peptide protein HR071_RS00190 ENOG4105FE9 pseudouridine synthase HR071_RS00205 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase HR071_RS00210 ENOG4105UBK short-chain dehydrogenase reductase HR071_RS00215 ENOG4105ERU peptidase HR071_RS00220 ENOG4105RKX Protein of unknown function (DUF2498) HR071_RS00225 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HR071_RS00230 ENOG4107R11 Transcriptional regulator HR071_RS00250 ENOG4107QM5 aconitate hydratase HR071_RS00260 ENOG4105EYK Phosphatidylglycerophosphatase B HR071_RS00265 ENOG4105Q4A inner membrane protein yciS HR071_RS00270 ENOG4105CFV Tetratricopeptide repeat protein HR071_RS00280 ENOG4108ZJT translation initiation factor, Sui1 HR071_RS00290 ENOG4105N2W Transcriptional regulator HR071_RS00295 ENOG410643D UPF0509 protein HR071_RS00300 ENOG4105BZU Histidine kinase HR071_RS00310 ENOG4108IEC Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity) HR071_RS00315 ENOG4105Q4T oxidoreductase HR071_RS00320 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HR071_RS00325 ENOG41067SE Tetr family transcriptional regulator HR071_RS00330 ENOG4105C1P efflux transporter, rnd family, mfp subunit HR071_RS00335 ENOG4105BZS acriflavin resistance protein HR071_RS00340 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HR071_RS00345 ENOG4105C2C drug resistance transporter, Bcr CflA HR071_RS00350 ENOG4108JQ2 peptide transport system atp-binding protein HR071_RS00355 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein HR071_RS00360 ENOG4108EU3 peptide transport system, permease HR071_RS00365 ENOG4108I5W peptide transport system, permease protein HR071_RS00370 ENOG4108HIY periplasmic HR071_RS00375 ENOG4105N0E Protein of unknown function (DUF2543) HR071_RS00385 ENOG4105E51 psp operon transcriptional activator HR071_RS00390 ENOG41087YS Phage shock protein A HR071_RS00395 ENOG4105YYT phage shock protein B HR071_RS00400 ENOG4105FM1 phage shock protein C HR071_RS00405 ENOG4105NNG Peripheral inner membrane phage-shock protein HR071_RS00410 ENOG4105K8Z Phage shock protein HR071_RS00415 ENOG4107QW3 Sucrose phosphorylase HR071_RS00420 ENOG4105WEM extracellular solute-binding protein HR071_RS00425 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component HR071_RS00430 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component HR071_RS00435 ENOG4107RRD Dehydrogenase HR071_RS00440 ENOG4107TYA transient receptor potential locus HR071_RS00445 ENOG4105CK5 oxidoreductase HR071_RS00450 ENOG4105C71 hydrolase family 65, central catalytic HR071_RS00455 ENOG4107URF beta-phospho-glucomutase HR071_RS00465 ENOG4107EFV Outer membrane protein G HR071_RS00470 ENOG4105FKQ transcriptional regulator HR071_RS00475 ENOG4105CM6 amino acid regulated cytosolic protein HR071_RS00485 ENOG4108JU8 Transcriptional regulator HR071_RS00490 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) HR071_RS00495 ENOG4107S8C mandelate racemase muconate lactonizing HR071_RS00500 ENOG4105KXI murein peptide amidase A HR071_RS00515 ENOG4105ENX hydrolase HR071_RS00520 ENOG4105EQ2 LysR family Transcriptional regulator HR071_RS00525 ENOG4107QSI ABC, transporter HR071_RS00530 ENOG4105D64 Mechanosensitive ion channel HR071_RS00535 ENOG4105S5I Membrane HR071_RS00540 ENOG4105Q9Y Universal stress protein HR071_RS00545 ENOG4105DS0 Transcriptional regulator, Crp Fnr family HR071_RS00550 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HR071_RS00560 ENOG4105R1U AraC Family Transcriptional Regulator HR071_RS00575 ENOG4108DG9 Smr protein MutS2 HR071_RS00580 ENOG4105BZU Histidine kinase HR071_RS00590 ENOG4105C1J atp-dependent rna helicase HR071_RS00615 ENOG4108RW8 Universal stress protein F HR071_RS00620 ENOG4105FCK Membrane HR071_RS00625 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) HR071_RS00630 ENOG4105IKK cytoplasmic protein HR071_RS00635 ENOG41090X5 Heat shock protein hslJ HR071_RS00640 ENOG4105C5I Dehydrogenase HR071_RS00645 ENOG4107H52 Dicarboxylate transport HR071_RS00650 ENOG410689M (LipO)protein HR071_RS00655 ENOG4105WXT Conserved Protein HR071_RS00670 ENOG4107EF2 surface-exposed virulence protein HR071_RS00675 ENOG4107S5I aldo keto reductase HR071_RS00680 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) HR071_RS00685 ENOG4105CQ7 ATP-dependent helicase HR071_RS00690 ENOG4107DB1 DUF218 domain HR071_RS00695 ENOG4105C26 Dehydrogenase HR071_RS00700 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HR071_RS00705 ENOG4105CPW cytochrome b561 HR071_RS00710 ENOG4105UPP uncharacterized protein ydcA HR071_RS00715 ENOG4107NK6 Hok/gef family HR071_RS00725 ENOG4105DDW LysR family Transcriptional regulator HR071_RS00730 ENOG4105E32 cytoplasmic protein HR071_RS00740 ENOG4105Z2P Protein of unknown function (DUF465) HR071_RS00745 ENOG4108Z9I -acetyltransferase HR071_RS00750 ENOG4107WE3 acetyltransferase YdcK HR071_RS00755 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein HR071_RS00760 ENOG41088CC tellurite resistance protein tehB HR071_RS00765 ENOG4108KKZ (LipO)protein HR071_RS00770 ENOG4105DKK Benzoate HR071_RS00775 ENOG4108JCI Transcriptional regulator HR071_RS00780 ENOG4105CFP Peptidase U32 HR071_RS00785 ENOG4105RR0 Protein of unknown function (DUF2554) HR071_RS00795 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HR071_RS00800 ENOG4107TYH extracellular solute-binding protein family 1 HR071_RS00805 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HR071_RS00810 ENOG4105D81 ABC transporter, permease HR071_RS00815 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component HR071_RS00830 ENOG410654E Membrane HR071_RS00835 ENOG4105R71 cytoplasmic protein HR071_RS00840 ENOG4108T9Y Inner membrane protein ydcZ HR071_RS00845 ENOG4108Z7F N-acetyltransferase HR071_RS00855 ENOG4105CHB tonB-dependent Receptor HR071_RS00860 ENOG4108NS2 receptor HR071_RS00865 ENOG4105C85 amino acid HR071_RS00870 ENOG410600T transposase HR071_RS00875 ENOG4108MEJ flavin reductase domain protein HR071_RS00880 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase HR071_RS00885 ENOG4105JAB phenazine biosynthesis protein, phzf family HR071_RS00890 ENOG4105D0D Nitrate reductase 2, gamma subunit HR071_RS00895 ENOG4108NZN Respiratory nitrate reductase 2 delta chain HR071_RS00900 ENOG4108IUE nitrate reductase beta subunit HR071_RS00905 ENOG4105CRU nitrate reductase, alpha subunit HR071_RS00910 ENOG4107QND Nitrite extrusion protein HR071_RS00915 ENOG4105RPH Inner membrane protein YddG HR071_RS00925 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HR071_RS00930 ENOG4108MG3 formate dehydrogenase HR071_RS00935 ENOG41084S7 Plasmid maintenance system antidote protein HR071_RS00945 ENOG4105DQ4 alcohol dehydrogenase HR071_RS00955 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein HR071_RS00960 ENOG4105TPS biofilm-dependent modulation protein HR071_RS00965 ENOG4108Z9K Osmotically inducible protein HR071_RS00970 ENOG4105BZU Histidine kinase HR071_RS00980 ENOG4105F32 YngK protein HR071_RS00985 ENOG4105E5D amino acid HR071_RS00990 ENOG4105CVK Glutamate decarboxylase HR071_RS00995 ENOG4107RAN Peptidase, M16 HR071_RS01000 ENOG4105C4X radical SAM domain protein HR071_RS01005 ENOG4105ENH Sulfatase HR071_RS01010 ENOG4108NKV transcriptional regulator HR071_RS01020 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HR071_RS01025 ENOG4106PIH fimbrial-like protein ydeQ HR071_RS01030 ENOG4106318 fimbrial-like protein YdeR HR071_RS01035 ENOG4108WDE Fimbrial protein HR071_RS01040 ENOG4105CW0 outer membrane usher protein HR071_RS01050 ENOG4108RQP Major type 1 subunit fimbrin HR071_RS01055 ENOG4105CAF HipA N-terminal domain protein HR071_RS01060 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein HR071_RS01070 ENOG4105FFC UPF0187 protein HR071_RS01080 ENOG4105BZU Histidine kinase HR071_RS01085 ENOG4105M0C cytoplasmic protein HR071_RS01090 ENOG4105CSV Glutaminase HR071_RS01095 ENOG4105C26 Dehydrogenase HR071_RS01100 ENOG4105EGI Transcriptional regulator HR071_RS01120 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes HR071_RS01125 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF HR071_RS01130 ENOG4106DNR multiple antibiotic resistance protein HR071_RS01135 ENOG4108594 Permease of the drug metabolite transporter HR071_RS01140 ENOG4105E5W Transporter HR071_RS01150 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria HR071_RS01160 ENOG4105DGW oligopeptidase A HR071_RS01165 ENOG4105EMU Dehydrogenase HR071_RS01170 ENOG4107XBN GntR Family Transcriptional Regulator HR071_RS01175 ENOG41061EV selenium-binding protein YdfZ HR071_RS01180 ENOG4105DEI Mannitol dehydrogenase HR071_RS01190 ENOG4105CPQ Dehydrogenase HR071_RS01195 ENOG4105CXK mandelate racemase muconate lactonizing HR071_RS01210 ENOG4108MK9 spermidine N(1)-acetyltransferase HR071_RS01220 ENOG4105KBG Protein of unknown function (DUF1161) HR071_RS01225 ENOG4107QY8 reductase HR071_RS01235 ENOG4105QAX Iron-sulfur HR071_RS01240 ENOG4107KGK dmso reductase anchor subunit HR071_RS01245 ENOG4108NEM leader-binding protein dmsD HR071_RS01255 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HR071_RS01260 ENOG4105DAG ROK family HR071_RS01265 ENOG4106NZI LysR family Transcriptional regulator HR071_RS01270 ENOG4105D94 Major Facilitator Superfamily HR071_RS01285 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap HR071_RS01300 ENOG4105DSF transport protein HR071_RS01305 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HR071_RS01310 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HR071_RS01315 ENOG4105C5D exported protein HR071_RS01320 ENOG4105D5Q Arginine ornithine antiporter HR071_RS01325 ENOG410642E Short chain dehydrogenase HR071_RS01330 ENOG4105RA2 Membrane HR071_RS01335 ENOG4107EXC regulatoR HR071_RS01340 ENOG4105JJR Histidine kinase HR071_RS01350 ENOG4105C9Q fumarate hydratase class II HR071_RS01355 ENOG4107GFK fumarate HR071_RS01360 ENOG4105EIP mannose-6-phosphate isomerase HR071_RS01365 ENOG4106J39 exported protein HR071_RS01380 ENOG4105CNT hydrolase family 2 HR071_RS01385 ENOG4105XEA Tetr family transcriptional regulator HR071_RS01390 ENOG4107ZQV short-chain dehydrogenase reductase HR071_RS01395 ENOG4107P2S Transcriptional regulator HR071_RS01400 ENOG4105CI1 PTS System HR071_RS01405 ENOG4105C87 Aminotransferase class I and II HR071_RS01415 ENOG4105D9R oxidoreductase HR071_RS01420 ENOG4106C6R beta-lactam resistance protein HR071_RS01425 ENOG4105QZ5 OriC-binding nucleoid-associated protein HR071_RS01430 ENOG4105M9B inner membrane protein ydgK HR071_RS01455 ENOG4108UQQ Electron transport complex HR071_RS01465 ENOG4105CSM endonuclease III HR071_RS01470 ENOG4105DUX Transporter HR071_RS01475 ENOG4108K3A Glutathione S-transferase HR071_RS01480 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) HR071_RS01495 ENOG410642K Lysozyme inhibitor HR071_RS01505 ENOG4108XTF Outer Membrane Lipoprotein HR071_RS01520 ENOG4105Y49 secretion protein, HlyD family HR071_RS01525 ENOG4105DSW Fusaric acid resistance protein HR071_RS01530 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HR071_RS01535 ENOG4107RGM aldo keto reductase HR071_RS01540 ENOG4105EQR Transposase IS116 IS110 IS902 HR071_RS01545 ENOG4105XZD Fe-S protein HR071_RS01550 ENOG4108WUH Transcriptional regulator, TetR family HR071_RS01555 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HR071_RS01560 ENOG4108UYE Lactoylglutathione lyase HR071_RS01570 ENOG4105M2J Glutaredoxin HR071_RS01575 ENOG4105K4H Nlp p60 protein HR071_RS01580 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HR071_RS01585 ENOG4105F27 Major Facilitator HR071_RS01600 ENOG4105F52 Transcriptional regulator HR071_RS01605 ENOG4105CZQ inner membrane transport protein YdhC HR071_RS01610 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HR071_RS01615 ENOG4108R6K riboflavin synthase, subunit alpha HR071_RS01640 ENOG4105N0V mono-oxygenase ydhR HR071_RS01645 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain HR071_RS01650 ENOG4108Y7C Conserved Protein HR071_RS01655 ENOG4108NWD Cytochrome HR071_RS01660 ENOG4108393 oxidoreductase Fe-S subunit HR071_RS01665 ENOG4105JVW HR071_RS01670 ENOG4105WE2 aldehyde ferredoxin oxidoreductase HR071_RS01675 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein HR071_RS01680 ENOG4105RFR Protein of unknown function (DUF2767) HR071_RS01685 ENOG4105CA9 Pyruvate kinase HR071_RS01690 ENOG4105KMX major outer membrane lipoprotein HR071_RS01695 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HR071_RS01715 ENOG4108SER Transposase HR071_RS01725 ENOG4105C3K feS assembly ATPase SufC HR071_RS01730 ENOG4105DIW FeS assembly protein SUFB HR071_RS01735 ENOG4108Z4V iron-sulfur cluster assembly HR071_RS01740 ENOG410671Z uncharacterized protein ydiH HR071_RS01745 ENOG4105KA0 thioesterase Superfamily protein HR071_RS01750 ENOG4105CQB FAD linked oxidase domain protein HR071_RS01755 ENOG4105IPI Membrane HR071_RS01765 ENOG4105SUA Ydil protein HR071_RS01770 ENOG4105EMV Major Facilitator HR071_RS01775 ENOG4105EMV Major Facilitator HR071_RS01790 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HR071_RS01795 ENOG4105C1G acyl-Coa dehydrogenase HR071_RS01800 ENOG4105W4W Transcriptional regulator HR071_RS01805 ENOG4105CV7 Electron transfer flavoprotein HR071_RS01810 ENOG4105C10 Electron transfer flavoprotein HR071_RS01815 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HR071_RS01820 ENOG41090P5 ferredoxin-like protein HR071_RS01825 ENOG4105CEY Amp-dependent synthetase and ligase HR071_RS01830 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) HR071_RS01840 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HR071_RS01850 ENOG4105CNG UPF0061 protein HR071_RS01855 ENOG4108TC0 Diguanylate phosphodiesterase HR071_RS01860 ENOG4108QBX (LipO)protein HR071_RS01870 ENOG4108V06 Glutathione peroxidase HR071_RS01905 ENOG41082NX 50s ribosomal protein l35 HR071_RS01910 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) HR071_RS01930 ENOG4108NE3 Salt-induced outer membrane protein HR071_RS01935 ENOG4105DE4 1-phosphofructokinase HR071_RS01940 ENOG4105P10 Uncharacterized protein ydiZ HR071_RS01950 ENOG4107PN8 YfeABCD locus regulator HR071_RS01955 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 HR071_RS01960 ENOG4107K5X Membrane-bound metal-dependent hydrolase HR071_RS01965 ENOG4108ETY sodium dicarboxylate symporter HR071_RS01985 ENOG4108YXQ IS66 Orf2 family protein HR071_RS01990 ENOG4105E5H Transposase HR071_RS02000 ENOG410901P UPF0249 protein HR071_RS02005 ENOG4105F8D glycoside hydrolase family 4 HR071_RS02010 ENOG4105EZV Transcriptional regulator HR071_RS02015 ENOG4105VCP PTS System HR071_RS02020 ENOG4105CK1 PTS System HR071_RS02025 ENOG4105VZJ PTS System HR071_RS02030 ENOG4105KKI DNA-binding transcriptional activator OsmE HR071_RS02035 ENOG4107RA1 nh(3)-dependent nad( ) synthetase HR071_RS02040 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) HR071_RS02050 ENOG4108SPG Periplasmic Protein HR071_RS02080 ENOG4105CGK Exodeoxyribonuclease III HR071_RS02085 ENOG4108RSN SNARE associated Golgi HR071_RS02090 ENOG4108KCW iron-sulfur cluster binding HR071_RS02095 ENOG4108N5C SNARE associated Golgi protein-related protein HR071_RS02100 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) HR071_RS02105 ENOG4105VNH ABC transporter solute-binding protein HR071_RS02110 ENOG4105CXZ ABC transporter, permease HR071_RS02115 ENOG4108VGW abc transporter atp-binding protein HR071_RS02120 ENOG4107RM6 sulfurtransferase HR071_RS02125 ENOG4108T9J Cdp-alcohol phosphatidyltransferase HR071_RS02130 ENOG4105M6F mutator MutT protein HR071_RS02135 ENOG4105MTM Protein of unknown function (DUF1496) HR071_RS02140 ENOG4105D82 Glutamate dehydrogenase HR071_RS02145 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HR071_RS02150 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) HR071_RS02155 ENOG41069NU Nitroreductase HR071_RS02160 ENOG4105D07 Signal peptide peptidase, SppA HR071_RS02170 ENOG4105HDK L-asparaginase HR071_RS02175 ENOG4108RWI nicotinamidase HR071_RS02180 ENOG4108KUU Inner membrane metabolite transport protein ydjE HR071_RS02185 ENOG4105E98 transcriptional regulator DeoR family HR071_RS02190 ENOG4105CPC Aldo Keto reductase HR071_RS02195 ENOG4107UH8 sugar kinase HR071_RS02200 ENOG4105D2N Aldolase HR071_RS02205 ENOG4105CPQ Dehydrogenase HR071_RS02210 ENOG4107TE1 transport protein HR071_RS02215 ENOG4105CPQ Dehydrogenase HR071_RS02220 ENOG4105VUT cytoplasmic protein HR071_RS02230 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HR071_RS02235 ENOG4105DSB aldose 1-epimerase HR071_RS02240 ENOG4105CV8 reductase HR071_RS02245 ENOG4105GNX MltA-interacting MipA family protein HR071_RS02250 ENOG4105CYN Serine protein kinase HR071_RS02260 ENOG4106KTS Inner membrane protein yeaI HR071_RS02265 ENOG4108KHP Diguanylate cyclase HR071_RS02270 ENOG4108KXH Ybak prolyl-tRNA synthetase associated HR071_RS02285 ENOG4105R1U AraC Family Transcriptional Regulator HR071_RS02290 ENOG4105DJ2 Major Facilitator Superfamily HR071_RS02295 ENOG4105K78 MarR family Transcriptional regulator HR071_RS02300 ENOG4105UCG Domain of unknown function (DUF333) HR071_RS02305 ENOG410620I Diguanylate cyclase HR071_RS02310 ENOG4106G4W HR071_RS02320 ENOG4105Y3U Transglycosylase-associated protein HR071_RS02325 ENOG4105YP6 Domain of unknown function (DUF1869) HR071_RS02330 ENOG4108YS1 cytoplasmic protein HR071_RS02340 ENOG4105EJC lysr family transcriptional regulator HR071_RS02345 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) HR071_RS02350 ENOG4105CEY Amp-dependent synthetase and ligase HR071_RS02355 ENOG4105Y4Z Outer Membrane Lipoprotein HR071_RS02360 ENOG41072GX Peptidase M22 Glycoprotease HR071_RS02365 ENOG4105DVT helicase HR071_RS02370 ENOG4105M4H endoribonuclease L-psp HR071_RS02375 ENOG4105V2F Uncharacterized protein yoac HR071_RS02385 ENOG4105CRQ synthase (Component I) HR071_RS02395 ENOG4105EJQ L-serine dehydratase HR071_RS02400 ENOG4107XTP (EAL) domain protein HR071_RS02405 ENOG4105EE5 Membrane protein terC HR071_RS02410 ENOG4105DAS pts system HR071_RS02415 ENOG4105ETZ PTS System HR071_RS02420 ENOG4105F3R pts system mannose fructose sorbose family iid HR071_RS02435 ENOG4105DHI Methyltransferase HR071_RS02450 ENOG4105Q3Y exported protein HR071_RS02460 ENOG4105TIK HR071_RS02465 ENOG4105J4Q Transcriptional regulator HR071_RS02470 ENOG4105C0R drug resistance transporter emrb qaca subfamily HR071_RS02480 ENOG4105CN1 protease HR071_RS02490 ENOG4108ZGC gaf domain protein HR071_RS02495 ENOG4105H2K paraquat-inducible protein a HR071_RS02500 ENOG4105DY2 Paraquat-inducible protein b HR071_RS02510 ENOG4105WT8 Protein of unknown function (DUF1480) HR071_RS02515 ENOG4105UVW uncharacterized protein yebW HR071_RS02520 ENOG4108R1E Serine threonine protein phosphatase 1 HR071_RS02525 ENOG4105NKT exported protein HR071_RS02530 ENOG4108PNC copper resistance HR071_RS02535 ENOG4105FXM Copper resistance protein HR071_RS02540 ENOG4105MPK DNA polymerase III subunit theta HR071_RS02545 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HR071_RS02550 ENOG4105UMD exodeoxyribonuclease X HR071_RS02555 ENOG4105CUG Oligopeptidase b HR071_RS02560 ENOG4108Q2J Inner membrane protein YebE HR071_RS02570 ENOG4105X2V dna damage-inducible protein HR071_RS02580 ENOG4108UHU Aldolase HR071_RS02585 ENOG4105C01 Dihydroxy-acid dehydratase HR071_RS02590 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase HR071_RS02595 ENOG4106KNT transcriptional regulator HR071_RS02600 ENOG4105CA9 Pyruvate kinase HR071_RS02605 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HR071_RS02610 ENOG4105DR5 peptidase HR071_RS02615 ENOG4105NXV High-affinity zinc uptake system protein HR071_RS02625 ENOG4105FAV ABC, transporter HR071_RS02650 ENOG4107S01 Repressor protein MetJ HR071_RS02660 ENOG4105CDY transcriptional regulatory protein HR071_RS02665 ENOG4108TIT dATP pyrophosphohydrolase HR071_RS02675 ENOG4105D3W isochorismatase HR071_RS02680 ENOG41081XQ Conserved Protein HR071_RS02685 ENOG4105WJG Glutathione HR071_RS02700 ENOG4108J2R molybdopterin oxidoreductase HR071_RS02705 ENOG4105CUW cytochrome C-TYPE protein HR071_RS02710 ENOG4108RS6 transposase HR071_RS02720 ENOG4106ZCM YecM protein HR071_RS02725 ENOG4105C75 arginyL-tRNA synthetase HR071_RS02730 ENOG4105W13 flagellar protein HR071_RS02735 ENOG4105D7B Flagellar biosynthesis protein flha HR071_RS02740 ENOG4105D00 flagellar biosynthetic protein flhB HR071_RS02745 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) HR071_RS02750 ENOG4108VYJ response regulator receiver protein HR071_RS02760 ENOG4105BZU Histidine kinase HR071_RS02770 ENOG4105C8Q Methyl-accepting chemotaxis HR071_RS02775 ENOG4108V3W Chemotaxis protein, CheW HR071_RS02780 ENOG4105CBS Chea signal transduction histidine kinase HR071_RS02785 ENOG4105ER2 Ompa motb domain protein HR071_RS02790 ENOG4107RD7 Flagellar Motor Protein, MotA HR071_RS02795 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region HR071_RS02805 ENOG4108VA4 Universal stress protein HR071_RS02810 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase HR071_RS02815 ENOG4108K4C ec 3.1.3.12 HR071_RS02820 ENOG4108C33 Resolvase HR071_RS02945 ENOG4108QUU Morphogenesis Protein HR071_RS02955 ENOG4105CF2 Mu-like prophage FluMu protein GP28 HR071_RS03050 ENOG4105IKI host-nuclease inhibitor protein HR071_RS03085 ENOG4105ZIA Phage protein gp16 HR071_RS03095 ENOG4105CNN ABC, transporter HR071_RS03100 ENOG4105C2J ABC transporter HR071_RS03105 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator HR071_RS03110 ENOG4108UEC Ferritin-like protein HR071_RS03115 ENOG4105N4N Protein of unknown function (DUF2766) HR071_RS03125 ENOG4105P23 (LipO)protein HR071_RS03130 ENOG41090A1 ferritin HR071_RS03135 ENOG4105VVZ metal-binding protein HR071_RS03140 ENOG4105E0U tyrosine-specific transport protein HR071_RS03145 ENOG4106RHG Yeca family HR071_RS03240 ENOG4105IM0 capsid protein HR071_RS03250 ENOG4105D07 Signal peptide peptidase, SppA HR071_RS03265 ENOG4105UZW Tail fiber assembly protein HR071_RS03305 ENOG4105RWQ Protein of unknown function (DUF1364) HR071_RS03375 ENOG4105CDU Replicative dna helicase HR071_RS03460 ENOG4105WH1 Two component transcriptional regulator luxr family HR071_RS03470 ENOG4105XVG cytoplasmic protein HR071_RS03475 ENOG4105VJY transcriptional regulator HR071_RS03480 ENOG4105CDA abc transporter atp-binding protein HR071_RS03485 ENOG4105E5Q amino acid AbC transporter HR071_RS03490 ENOG4105K6H D-cysteine desulfhydrase HR071_RS03495 ENOG4105EAB amino acid AbC transporter HR071_RS03500 ENOG4108M9K flagella biosynthesis protein FliZ HR071_RS03505 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HR071_RS03510 ENOG4105I03 Flagellin HR071_RS03515 ENOG4105DTS flagellar hook-associated HR071_RS03520 ENOG4105MQ3 flagellar protein FliS HR071_RS03530 ENOG4105E5K Alpha-amylase HR071_RS03535 ENOG4108W9D (LipO)protein HR071_RS03540 ENOG41066VF YeeE YedE family protein HR071_RS03550 ENOG4108RAV Conserved protein HR071_RS03555 ENOG4105D7V transposase HR071_RS03560 ENOG4108RS6 transposase HR071_RS03565 ENOG4108UQN AraC family transcriptional regulator HR071_RS03570 ENOG4108V1U phospholipid-binding protein HR071_RS03575 ENOG410814C multidrug resistance protein HR071_RS03580 ENOG4105VQ0 flagellar hook-basal body complex protein fliE HR071_RS03585 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) HR071_RS03590 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HR071_RS03595 ENOG41090PJ Flagellar assembly protein HR071_RS03600 ENOG4108JIR Flagellum-specific ATP synthase HR071_RS03605 ENOG4105GSA Flagellar export protein flij HR071_RS03610 ENOG4105WF4 Flagellar hook-length control protein HR071_RS03615 ENOG4107ZI8 flagellar basal body-associated protein flil HR071_RS03620 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) HR071_RS03625 ENOG4105DD5 Flagellar motor switch protein HR071_RS03630 ENOG4105K0P flagellar biosynthesis protein HR071_RS03635 ENOG4105CN7 Flagellar biosynthetic protein FliP HR071_RS03645 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HR071_RS03650 ENOG4107TKS colanic acid capsular biosynthesis activation protein A HR071_RS03660 ENOG4105YX3 cellular response to acidity HR071_RS03665 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase HR071_RS03670 ENOG4105BZU Histidine kinase HR071_RS03675 ENOG4105VNZ cytoplasmic protein HR071_RS03680 ENOG4105CKW Inner membrane protein yedI HR071_RS03685 ENOG4105FDR Membrane HR071_RS03690 ENOG41090BB DNA mismatch endonuclease (vsr) HR071_RS03695 ENOG4105DVF Cytosine-specific methyltransferase HR071_RS03700 ENOG4105EST Metal Dependent Phosphohydrolase HR071_RS03705 ENOG4105Y0K Inner membrane protein YedR HR071_RS03710 ENOG4105ZIT Porin Gram-negative type HR071_RS03720 ENOG4107ZY3 Histidine kinase HR071_RS03725 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HR071_RS03730 ENOG4105VT2 5-hydroxyisourate hydrolase HR071_RS03740 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) HR071_RS03750 ENOG4108MEK Metal-binding protein YodA HR071_RS03780 ENOG4105EYM Major Facilitator superfamily HR071_RS03785 ENOG4105BZ1 (ABC) transporter HR071_RS03800 ENOG4105C0W non-ribosomal peptide synthetase HR071_RS03820 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HR071_RS03825 ENOG4107ZSV Receptor HR071_RS03830 ENOG4105TNG K13735 adhesin invasin HR071_RS03835 ENOG4105TNG K13735 adhesin invasin HR071_RS03840 ENOG4105TNG K13735 adhesin invasin HR071_RS03850 ENOG4105CSH Transporter HR071_RS03855 ENOG4105FYV Amp nucleosidase HR071_RS03860 ENOG4105CDY transcriptional regulatory protein HR071_RS03870 ENOG4105UQX Mate efflux family protein HR071_RS03880 ENOG4107R11 Transcriptional regulator HR071_RS03885 ENOG4106P55 Transcriptional regulator HR071_RS03895 ENOG4108PXI ErfK YbiS YcfS YnhG HR071_RS03910 ENOG4108YZT Adenosylcobinamide kinase HR071_RS03925 ENOG4105GTN ParB Domain Protein Nuclease HR071_RS03930 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HR071_RS03935 ENOG4107W19 lmbE family HR071_RS03940 ENOG4108PBI Polysaccharide metabolism HR071_RS03945 ENOG4107RMY Bacterial transferase hexapeptide repeat protein HR071_RS03950 ENOG4105SRB Uncharacterized protein yaiO HR071_RS03960 ENOG4108RVA ribokinase HR071_RS03975 ENOG41080QX K07048 phosphotriesterase-related protein HR071_RS04015 ENOG410836F Transposase HR071_RS04070 ENOG4108F1U ABC transporter HR071_RS04075 ENOG4105EHG Permease protein HR071_RS04095 ENOG4108F5E vimentin HR071_RS04100 ENOG4108YIV HR071_RS04120 ENOG4106H6R UPF0380 protein HR071_RS04130 ENOG4106549 Antirestriction protein HR071_RS04135 ENOG4108YGG dna repair protein HR071_RS04150 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HR071_RS04170 ENOG4105E5H Transposase HR071_RS04185 ENOG4105DR8 Membrane HR071_RS04195 ENOG4105DZ1 carboxypeptidase HR071_RS04200 ENOG4105CJB Exodeoxyribonuclease I HR071_RS04205 ENOG4108RS6 transposase HR071_RS04210 ENOG4105CUB amino acid HR071_RS04220 ENOG4105EQ1 Transcriptional regulator HR071_RS04225 ENOG4107SRH Nad-dependent epimerase dehydratase HR071_RS04230 ENOG4105KRQ Addiction module toxin, Txe YoeB family HR071_RS04235 ENOG4105VTW prevent-host-death family HR071_RS04250 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HR071_RS04260 ENOG4105ECC imidazole-glycerol-phosphate dehydratase HR071_RS04265 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HR071_RS04285 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) HR071_RS04290 ENOG4105C6Y Udp-glucose 6-dehydrogenase HR071_RS04295 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) HR071_RS04305 ENOG4108TMJ glycosyl transferase HR071_RS04310 ENOG4108UW5 maltose o-acetyltransferase HR071_RS04320 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) HR071_RS04330 ENOG4108MX3 Polysaccharide Biosynthesis Protein HR071_RS04335 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase HR071_RS04340 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HR071_RS04345 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase HR071_RS04350 ENOG4105C1B dTDP-glucose 4-6-dehydratase HR071_RS04355 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HR071_RS04360 ENOG4105G1A colanic acid biosynthesis protein HR071_RS04365 ENOG4107T8Q Glycosyl transferase (Group 1 HR071_RS04370 ENOG4105C74 pyruvyl transferase HR071_RS04375 ENOG4105PSV Polysaccharide Biosynthesis Protein HR071_RS04380 ENOG4105D3Q Sugar transferase HR071_RS04385 ENOG4107QKV phosphomannomutase HR071_RS04390 ENOG4105CJT Mannose-1-phosphate guanylyltransferase HR071_RS04395 ENOG4106CD9 glycosyl transferase group 1 HR071_RS04400 ENOG4105FGF GDP-mannose mannosyl hydrolase HR071_RS04405 ENOG4105C30 Nad-dependent epimerase dehydratase HR071_RS04410 ENOG4105C0K Gdp-mannose 4,6-dehydratase HR071_RS04415 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF HR071_RS04420 ENOG4105ECJ Glycosyl Transferase HR071_RS04425 ENOG4108NYJ Colanic acid HR071_RS04430 ENOG4107RXY Glycosyl transferase HR071_RS04435 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB HR071_RS04440 ENOG41090RK glycosyl transferase HR071_RS04445 ENOG4105D75 Capsular exopolysaccharide family HR071_RS04450 ENOG4105KJF protein tyrosine phosphatase HR071_RS04455 ENOG4105DAY polysaccharide export protein HR071_RS04465 ENOG4105EE5 Membrane protein terC HR071_RS04470 ENOG4108GAE asmA family HR071_RS04480 ENOG4105DBI uridine monophosphokinase HR071_RS04485 ENOG4105BZU Histidine kinase HR071_RS04490 ENOG4105D03 DNA-3-methyladenine glycosylase II HR071_RS04495 ENOG4105R8A Heat shock protein HR071_RS04500 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding HR071_RS04505 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase HR071_RS04510 ENOG4108M24 von Willebrand factor, type A HR071_RS04525 ENOG4105ENT Efflux transporter rnd family, mfp subunit HR071_RS04530 ENOG4105BZS acriflavin resistance protein HR071_RS04540 ENOG4105C0R drug resistance transporter emrb qaca subfamily HR071_RS04545 ENOG4105EB3 Histidine kinase HR071_RS04550 ENOG4105E3W Two component transcriptional regulator (Winged helix family HR071_RS04555 ENOG4105KWI UPF0339 protein HR071_RS04560 ENOG4105CFP Peptidase U32 HR071_RS04565 ENOG41076Z6 Uncharacterized protein yegR HR071_RS04570 ENOG4107TE5 Lipid kinase HR071_RS04580 ENOG4107WTH Galactitol-1-phosphate dehydrogenase HR071_RS04590 ENOG41090UW PTS System HR071_RS04595 ENOG41082GB PTS system galactitol-specific transporter subunit IIA HR071_RS04600 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of HR071_RS04605 ENOG4105D2N Aldolase HR071_RS04610 ENOG4105EIE fructose-bisphosphate aldolase HR071_RS04615 ENOG4105EAA nucleoside HR071_RS04620 ENOG4108KD5 ADP-ribosylation crystallin J1 HR071_RS04625 ENOG4108TFM Kinase, PfkB family HR071_RS04630 ENOG4105FDP GntR family transcriptional regulator HR071_RS04635 ENOG4108UQ1 hydrolase, family 25 HR071_RS04640 ENOG4105DWF phosphomethylpyrimidine kinase HR071_RS04660 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly HR071_RS04665 ENOG410662B Type-1 fimbrial protein HR071_RS04670 ENOG4105CW0 outer membrane usher protein HR071_RS04675 ENOG4108MQF Chaperone HR071_RS04680 ENOG41063W2 Fimbrial protein HR071_RS04685 ENOG41067AK Protein of unknown function (DUF2574) HR071_RS04690 ENOG4105D1F ATP-binding protein HR071_RS04700 ENOG4108KDT Molybdate metabolism regulator HR071_RS04705 ENOG4108KDT Molybdate metabolism regulator HR071_RS04710 ENOG4108KDT Molybdate metabolism regulator HR071_RS04720 ENOG4105KKX ATPase associated with various cellular activities aaa_5 HR071_RS04725 ENOG4105RD5 HR071_RS04730 ENOG4105DEG Vwa containing coxe family protein HR071_RS04735 ENOG410903U zinc ion binding HR071_RS04740 ENOG4108YCW (LipO)protein HR071_RS04745 ENOG4108W15 Protein of unknown function (DUF1456) HR071_RS04750 ENOG4108NEV two component transcriptional regulator, LytTR family HR071_RS04755 ENOG4108HRK Histidine kinase HR071_RS04760 ENOG4108XDN Transcriptional regulator HR071_RS04770 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component HR071_RS04775 ENOG4108IJ8 ABC transporter HR071_RS04780 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component HR071_RS04785 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system HR071_RS04790 ENOG4107QK4 glycoside hydrolase, family 3 domain protein HR071_RS04795 ENOG4105CXG d-lactate dehydrogenase HR071_RS04800 ENOG41061WM D-Alanyl-D-Alanine HR071_RS04805 ENOG41069YE inner membrane protein yohC HR071_RS04810 ENOG4105KHU inner membrane protein YohD HR071_RS04815 ENOG4105H9W Short-chain dehydrogenase reductase Sdr HR071_RS04820 ENOG4105ETP RND efflux system, outer membrane lipoprotein HR071_RS04830 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HR071_RS04840 ENOG41067MG lrgb family HR071_RS04850 ENOG4107GZ4 SanA protein HR071_RS04855 ENOG4105Y9N Membrane HR071_RS04860 ENOG4105BZ8 glutamate synthase HR071_RS04865 ENOG4107SJI Dehydrogenase HR071_RS04870 ENOG4108HWV )-transporter HR071_RS04875 ENOG4105C2J ABC transporter HR071_RS04880 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator HR071_RS04885 ENOG41060NJ transcriptional regulator HR071_RS04890 ENOG4105DHF Membrane HR071_RS04905 ENOG4105D05 Receptor HR071_RS04910 ENOG4108IQI permease HR071_RS04915 ENOG4105DUM transcriptional regulator, lysR family HR071_RS04920 ENOG4105HMI Membrane HR071_RS04930 ENOG4105DD7 kinase (PfkB family HR071_RS04940 ENOG4108Y4K DNA-binding transcriptional activator HR071_RS04945 ENOG4105D9N nucleoside HR071_RS04950 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) HR071_RS04955 ENOG4105DD7 kinase (PfkB family HR071_RS04960 ENOG4105DM4 PTS System HR071_RS04965 ENOG4105DE4 1-phosphofructokinase HR071_RS04970 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein HR071_RS04975 ENOG4105S8Q sugar efflux transporter HR071_RS04980 ENOG4105KRS Proteinase inhibitor HR071_RS04990 ENOG4105DEI Mannitol dehydrogenase HR071_RS04995 ENOG4105CKI cobalamin synthesis protein HR071_RS05000 ENOG41076MN Phosphoesterase, PA-phosphatase related HR071_RS05005 ENOG4107TT5 NLP P60 protein HR071_RS05010 ENOG4105CXC rtn protein HR071_RS05015 ENOG4105E43 Extracellular solute-binding protein, family 5 HR071_RS05020 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HR071_RS05025 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HR071_RS05030 ENOG4108JQ5 ABC transporter HR071_RS05035 ENOG4105HG6 HR071_RS05040 ENOG4105C2C drug resistance transporter, Bcr CflA HR071_RS05045 ENOG4105I08 Pseudouridine synthase HR071_RS05050 ENOG4105CFI type iii restriction protein res subunit HR071_RS05070 ENOG4105E68 Sulfatase HR071_RS05085 ENOG4105WH1 Two component transcriptional regulator luxr family HR071_RS05090 ENOG4105KWW Biogenesis protein HR071_RS05095 ENOG4107QX9 Thiol disulfide interChange protein HR071_RS05100 ENOG4105DA4 cytochrome c-type biogenesis protein HR071_RS05110 ENOG4105X3C heme exporter protein HR071_RS05115 ENOG41060IM Heme exporter protein HR071_RS05120 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) HR071_RS05125 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) HR071_RS05130 ENOG4105CUW cytochrome C-TYPE protein HR071_RS05135 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) HR071_RS05140 ENOG4105GXZ Ferredoxin-type protein NapH HR071_RS05145 ENOG4108BGM Quinol dehydrogenase periplasmic component HR071_RS05155 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase HR071_RS05160 ENOG4108ZNS ferredoxin-type protein NapF HR071_RS05180 ENOG4105IBP Cyclic peptide transporter HR071_RS05185 ENOG4105CF1 Alkylated DNA repair protein HR071_RS05190 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HR071_RS05195 ENOG4105CJ2 (LipO)protein HR071_RS05200 ENOG4105FCK Membrane HR071_RS05205 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC HR071_RS05210 ENOG41068CG regulatoR HR071_RS05215 ENOG4105BZU Histidine kinase HR071_RS05220 ENOG4105BZU Histidine kinase HR071_RS05225 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HR071_RS05230 ENOG4107QP7 CoA-transferase subunit A HR071_RS05235 ENOG4107QNJ CoA-transferase subunit B HR071_RS05240 ENOG4105CRW Short chain fatty acid transporter HR071_RS05245 ENOG4105CHU acetyl-coa acetyltransferase HR071_RS05250 ENOG4105EDV vault protein HR071_RS05255 ENOG41081SK signal peptide protein HR071_RS05260 ENOG4107S52 alpha-2-macroglobulin domain protein HR071_RS05265 ENOG4108QJJ Protein of unknown function (DUF1175) HR071_RS05270 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) HR071_RS05275 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HR071_RS05285 ENOG4107GHC outer membrane autotransporter HR071_RS05290 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HR071_RS05295 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HR071_RS05300 ENOG4105XPH Ferredoxin HR071_RS05305 ENOG4105FQR PH-inducible protein involved in stress response HR071_RS05310 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HR071_RS05315 ENOG4105CXY transporter HR071_RS05320 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A HR071_RS05330 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HR071_RS05335 ENOG4105DNE Transposase HR071_RS05345 ENOG4105CNV Aldolase HR071_RS05350 ENOG4105CSP Major Facilitator Superfamily HR071_RS05355 ENOG4105CXK mandelate racemase muconate lactonizing HR071_RS05360 ENOG4107258 Transcriptional regulator HR071_RS05365 ENOG4108EWA cinA-like protein HR071_RS05370 ENOG4108UII YfaZ family HR071_RS05405 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) HR071_RS05420 ENOG4106GZG polymyxin resistance protein B HR071_RS05425 ENOG4105CEY Amp-dependent synthetase and ligase HR071_RS05435 ENOG4108IPT Naphthoate synthase HR071_RS05450 ENOG4105E4F Isochorismate synthase HR071_RS05455 ENOG4105TNS Conserved Protein HR071_RS05460 ENOG4107YB6 acetyltransferase, (GNAT) family HR071_RS05470 ENOG4105CP2 von willebrand factor, type a HR071_RS05475 ENOG4107VAM peptidase, m28 HR071_RS05480 ENOG4105GDX Domain of unknown function (DUF1877) HR071_RS05490 ENOG4105C8S subunit m HR071_RS05495 ENOG4105D65 subunit l HR071_RS05505 ENOG4107UFS subunit j HR071_RS05520 ENOG4108IEH NADH dehydrogenase subunit g HR071_RS05525 ENOG4107QIZ NADH dehydrogenase HR071_RS05530 ENOG4105GKE subunit e HR071_RS05550 ENOG4107NQ8 LysR family Transcriptional regulator HR071_RS05555 ENOG4105CHM Aminotransferase HR071_RS05565 ENOG4107QWE )-transporter HR071_RS05570 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 HR071_RS05575 ENOG4105XWI UPF0304 protein HR071_RS05585 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HR071_RS05590 ENOG4105C6K Malic enzyme HR071_RS05595 ENOG4105CSX c4-dicarboxylate anaerobic carrier HR071_RS05600 ENOG4105PTV Nudix Hydrolase HR071_RS05605 ENOG4108RE9 Phosphodiesterase HR071_RS05610 ENOG4108SHQ Glutathione S-transferase HR071_RS05615 ENOG4105CYM Glutathione S-transferase HR071_RS05620 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase HR071_RS05625 ENOG4105ECP epimerase HR071_RS05630 ENOG4108JEH abc transporter atp-binding protein HR071_RS05635 ENOG4106YG3 ABC transporter HR071_RS05640 ENOG4105DSP amino acid AbC transporter HR071_RS05645 ENOG4105E89 ABC transporter HR071_RS05650 ENOG4105E89 ABC transporter HR071_RS05655 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HR071_RS05660 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HR071_RS05665 ENOG4105E96 Colicin v production protein HR071_RS05670 ENOG4108S3P Sporulation domain protein HR071_RS05675 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HR071_RS05685 ENOG4105DQR SNARE associated Golgi HR071_RS05695 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HR071_RS05705 ENOG4106WZ1 flagella biosynthesis regulator HR071_RS05710 ENOG4105F9N Major Facilitator Superfamily HR071_RS05715 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HR071_RS05720 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) HR071_RS05725 ENOG4105MH2 YfcL protein HR071_RS05730 ENOG4108BPE -transporting atpase HR071_RS05735 ENOG4105EJ9 Membrane HR071_RS05740 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) HR071_RS05745 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase HR071_RS05765 ENOG4105US4 fimbrial-like protein yfcP HR071_RS05770 ENOG4105UGQ Fimbrial HR071_RS05775 ENOG4105NEV Fimbrial HR071_RS05780 ENOG4108FZ9 Chaperone HR071_RS05785 ENOG4106PG1 outer membrane usher protein HR071_RS05795 ENOG4108BY2 phosphohistidine phosphatase HR071_RS05810 ENOG4105KZW UPF0381 protein HR071_RS05815 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation HR071_RS05820 ENOG410903C (LipO)protein HR071_RS05825 ENOG4105S64 Formate nitrite transporter HR071_RS05835 ENOG4105DFP Integrase HR071_RS05890 ENOG4105W8I Transcriptional regulator HR071_RS05905 ENOG4105C0R drug resistance transporter emrb qaca subfamily HR071_RS05910 ENOG4105CW7 secretion protein, HlyD family HR071_RS05915 ENOG4108WQH regulatoR HR071_RS05920 ENOG4105BZU Histidine kinase HR071_RS05925 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HR071_RS05930 ENOG4108N2Y auxin Efflux HR071_RS05935 ENOG4105CFN oxalyl-CoA decarboxylase HR071_RS05945 ENOG4108V08 YfdX protein HR071_RS05955 ENOG4105W9M Membrane HR071_RS05960 ENOG4105D1S lipid A biosynthesis HR071_RS05970 ENOG4105CHM Aminotransferase HR071_RS05975 ENOG4108HRK Histidine kinase HR071_RS05980 ENOG4105DY9 regulatoR HR071_RS05985 ENOG4108CIP transcriptional regulator HR071_RS05990 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HR071_RS05995 ENOG4105CN9 Peptidase m42 family protein HR071_RS06000 ENOG4105DC7 peptidase M24 HR071_RS06005 ENOG410863U PTS System HR071_RS06010 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HR071_RS06020 ENOG4105VCT ion-transport protein YfeO HR071_RS06025 ENOG4109076 Conserved Protein HR071_RS06035 ENOG4105D9N nucleoside HR071_RS06040 ENOG4108SER Transposase HR071_RS06045 ENOG4108KMM Diguanylate cyclase HR071_RS06060 ENOG4105HZG regulatoR HR071_RS06065 ENOG4105GXM Putative transcription regulator (DUF1323) HR071_RS06070 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) HR071_RS06095 ENOG4105CN8 Transcriptional regulator HR071_RS06105 ENOG4105EAA nucleoside HR071_RS06110 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) HR071_RS06115 ENOG4108NFH Sugar hydrolase HR071_RS06120 ENOG4108M0I Transcriptional regulator HR071_RS06125 ENOG4105DHU Bile acid HR071_RS06130 ENOG4105VRT cytoplasmic protein HR071_RS06150 ENOG4105C6T cysteine synthase HR071_RS06160 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HR071_RS06165 ENOG4105C5Y PTS System HR071_RS06175 ENOG4105M0Y HR071_RS06180 ENOG4105C6T cysteine synthase HR071_RS06185 ENOG4108IJ6 ABC transporter HR071_RS06190 ENOG4105ECW sulfate abc transporter HR071_RS06195 ENOG4108I5D sulfate abc transporter HR071_RS06200 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein HR071_RS06205 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr HR071_RS06210 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate HR071_RS06215 ENOG4105C5Y PTS System HR071_RS06220 ENOG4105EZR dyp-type peroxidase family protein HR071_RS06225 ENOG4105E7K (LipO)protein HR071_RS06230 ENOG4105QZU Inner membrane protein YfeZ HR071_RS06240 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase HR071_RS06250 ENOG4108K3Z AraC family transcriptional regulator HR071_RS06255 ENOG4108X49 Ethanolamine utilization protein EutK HR071_RS06260 ENOG4106D67 ethanolamine utilization protein HR071_RS06270 ENOG4105CPD ethanolamine ammonia-lyase HR071_RS06275 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase HR071_RS06280 ENOG4105ENY Ethanolamine utilization protein eutH HR071_RS06285 ENOG4105C0A alcohol dehydrogenase HR071_RS06290 ENOG4107RWI ethanolamine utilization protein eutJ HR071_RS06295 ENOG4108EKI Dehydrogenase HR071_RS06300 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml HR071_RS06305 ENOG4105KNY Microcompartments protein HR071_RS06310 ENOG4107WUY phosphate acetyltransferase HR071_RS06315 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase HR071_RS06320 ENOG4105NDK ethanolamine utilization protein HR071_RS06325 ENOG4106S4J ethanolamine utilization protein EutP HR071_RS06330 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place HR071_RS06335 ENOG4105C6K Malic enzyme HR071_RS06340 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HR071_RS06345 ENOG4105CV1 Transketolase (EC 2.2.1.1) HR071_RS06350 ENOG4108PVD exported protein HR071_RS06360 ENOG4105BZ8 glutamate synthase HR071_RS06365 ENOG4105BZU Histidine kinase HR071_RS06370 ENOG4105BZS acriflavin resistance protein HR071_RS06380 ENOG4105KUZ arsenate reductase HR071_RS06395 ENOG4106KED esterase YpfH HR071_RS06405 ENOG4105CGZ zinc metallopeptidase HR071_RS06415 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HR071_RS06425 ENOG4105RH4 Glycine cleavage system transcriptional repressor HR071_RS06430 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HR071_RS06435 ENOG4105C02 permease HR071_RS06440 ENOG4105ERG peptidase m48, ste24p HR071_RS06445 ENOG4105K89 arsenate reductase HR071_RS06450 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) HR071_RS06455 ENOG4105C2W permease HR071_RS06465 ENOG4105CXB phosphoribosylaminoimidazole synthetase HR071_RS06470 ENOG4108V3E phosphoribosylglycinamide formyltransferase HR071_RS06475 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) HR071_RS06480 ENOG4105C9X ppx gppa phosphatase HR071_RS06485 ENOG4105BZU Histidine kinase HR071_RS06495 ENOG41062G3 Protein of unknown function (DUF2633) HR071_RS06500 ENOG4108ZMA Outer membrane lipoprotein HR071_RS06505 ENOG41066DY Membrane HR071_RS06515 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HR071_RS06540 ENOG4105VPD cellular component movement HR071_RS06555 ENOG4105N21 Membrane HR071_RS06585 ENOG4108JQB penicillin-binding protein 1C HR071_RS06590 ENOG4105DN3 alpha-2-macroglobulin domain protein HR071_RS06595 ENOG4105KHC sulfurtransferase HR071_RS06600 ENOG4105YYA enhanced serine sensitivity protein SseB HR071_RS06610 ENOG4105WVQ Fe-S assembly protein IscX HR071_RS06615 ENOG4108ZIT Ferredoxin, 2FE-2S HR071_RS06635 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HR071_RS06655 ENOG4105ECY inositol monophosphatase HR071_RS06660 ENOG4107XM9 (LipO)protein HR071_RS06665 ENOG4108MN2 Stationary phase inducible protein CsiE HR071_RS06670 ENOG4105D8G Major Facilitator superfamily HR071_RS06675 ENOG4108SB3 DoxX Family HR071_RS06680 ENOG4108ZKT aldose 1-epimerase HR071_RS06685 ENOG4105CPQ Dehydrogenase HR071_RS06690 ENOG4105CNN ABC, transporter HR071_RS06695 ENOG4108F37 ATP-binding component of a transport system HR071_RS06700 ENOG4105FCA ABC transporter periplasmic-binding protein YphF HR071_RS06705 ENOG4107HQ7 repeat protein HR071_RS06710 ENOG4108NZE NAGC-like transcriptional regulator HR071_RS06720 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HR071_RS06730 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HR071_RS06735 ENOG4108SKK alpha helix protein HR071_RS06740 ENOG4107WP9 Histidine kinase HR071_RS06745 ENOG4108ETH Formylglycinamide ribotide synthetase HR071_RS06755 ENOG4108Z6B deaminase HR071_RS06760 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB HR071_RS06765 ENOG4106G6Q Transcriptional regulator HR071_RS06770 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HR071_RS06785 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HR071_RS06805 ENOG4105C3F Signal peptidase i HR071_RS06815 ENOG4105WMJ Positive regulator of sigma E, RseC MucC HR071_RS06820 ENOG4105VQK sigma E regulatory protein, MucB RseB HR071_RS06825 ENOG41069PW sigma-e factor negative regulatory protein HR071_RS06830 ENOG4105EMN RNA polymerase sigma factor HR071_RS06840 ENOG4108IYU L-aspartate oxidase HR071_RS06850 ENOG4105C1J atp-dependent rna helicase HR071_RS06855 ENOG41090KR LysR family transcriptional Regulator HR071_RS06875 ENOG4105EIB trna rrna methyltransferase HR071_RS06880 ENOG4105K63 Thioredoxin HR071_RS06885 ENOG4106IUH DTW domain containing protein HR071_RS06890 ENOG4105CD5 CoA-binding domain protein HR071_RS06895 ENOG4105JIM Phosphatidylserine synthase HR071_RS06900 ENOG4105T42 (LipO)protein HR071_RS06905 ENOG4105CSH Transporter HR071_RS06930 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HR071_RS06935 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HR071_RS06940 ENOG4105C34 Pseudouridine synthase HR071_RS06945 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HR071_RS06950 ENOG4105VNT transposase (IS4 family) protein HR071_RS06955 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA HR071_RS06965 ENOG4105CQC Prephenate dehydratase HR071_RS06970 ENOG4105EHE chorismate mutase- prephenate dehydrogenase HR071_RS06975 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HR071_RS06980 ENOG4105QP9 Protein of unknown function (DUF2799) HR071_RS06985 ENOG4108WS1 HR071_RS06990 ENOG4108KHX Diguanylate cyclase HR071_RS06995 ENOG41090EK ompa motb domain protein HR071_RS07020 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HR071_RS07025 ENOG4106KVJ cytochrome C assembly protein HR071_RS07030 ENOG4108JU6 CBS domain protein HR071_RS07045 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HR071_RS07050 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HR071_RS07060 ENOG4108Z1B Cyclase dehydrase HR071_RS07080 ENOG4105D5U fad dependent oxidoreductase HR071_RS07085 ENOG4105C26 Dehydrogenase HR071_RS07090 ENOG4108JPW Aminotransferase HR071_RS07095 ENOG4105C85 amino acid HR071_RS07100 ENOG4108PVQ transcriptional regulator HR071_RS07105 ENOG4109066 lysm domain bon superfamily protein HR071_RS07110 ENOG4105VPI YqaE family transport protein HR071_RS07115 ENOG41080HT Transcriptional regulator, arsr family HR071_RS07120 ENOG4108V62 Rhodanese domain protein HR071_RS07125 ENOG4108X73 DNA- binding protein HR071_RS07130 ENOG4108RNS Exports L-alanine (By similarity) HR071_RS07135 ENOG4108WMJ Protein of unknown function (DUF2002) HR071_RS07140 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) HR071_RS07145 ENOG4105WAZ (Glutaredoxin-like protein) NrdH HR071_RS07155 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HR071_RS07160 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HR071_RS07165 ENOG4108IJ7 Glycine betaine HR071_RS07170 ENOG4108HQS Glycine betaine HR071_RS07175 ENOG4105GIJ Glycine betaine HR071_RS07185 ENOG4108UMN azlc family HR071_RS07190 ENOG4105ZED uncharacterized protein ygaH HR071_RS07195 ENOG4105NTK Transcriptional repressor Mpra HR071_RS07200 ENOG4105CW7 secretion protein, HlyD family HR071_RS07205 ENOG4105C0R drug resistance transporter emrb qaca subfamily HR071_RS07230 ENOG4105W39 Membrane HR071_RS07235 ENOG4107VXZ Hydrolase HR071_RS07265 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) HR071_RS07285 ENOG4107TH8 cina domain protein HR071_RS07295 ENOG4105CVE Lytic murein transglycosylase HR071_RS07300 ENOG410787A Pts system, glucitol sorbitol-specific HR071_RS07305 ENOG4105DZY Pts system, glucitol sorbitol-specific HR071_RS07310 ENOG4105VI0 Pts system, glucitol sorbitol-specific HR071_RS07315 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase HR071_RS07320 ENOG4105J92 DNA-binding transcriptional activator GutM HR071_RS07325 ENOG410804X Transcriptional regulator HR071_RS07330 ENOG4105C2X Arabinose 5-phosphate isomerase HR071_RS07350 ENOG4105C8H hydrogenase maturation protein Hypf HR071_RS07355 ENOG4108RC0 Electron transport protein HR071_RS07365 ENOG4108Z3N Transcriptional regulator HR071_RS07375 ENOG4108MG9 hydrogenase 3 maturation protease HR071_RS07380 ENOG4105I6X formate hydrogenlyase maturation HR071_RS07385 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit HR071_RS07390 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit HR071_RS07395 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) HR071_RS07400 ENOG4107TDF Formate hydrogenlyase subunit 4 HR071_RS07405 ENOG4107R30 NADH dehydrogenase HR071_RS07410 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) HR071_RS07415 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA HR071_RS07420 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HR071_RS07425 ENOG4107RSS Hydrogenase accessory protein HypB HR071_RS07430 ENOG41083WG hydrogenase assembly chaperone HR071_RS07435 ENOG4105CQS hydrogenase expression formation protein HypD HR071_RS07440 ENOG4105C45 hydrogenase expression formation protein (HypE) HR071_RS07445 ENOG4108JUA Transcriptional regulator HR071_RS07455 ENOG4105VXR cytoplasmic protein HR071_RS07460 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) HR071_RS07465 ENOG4105MEW serine threonine protein phosphatase HR071_RS07470 ENOG4105MVE transcriptional regulator HR071_RS07480 ENOG4105G63 Type III effector Hrp-dependent HR071_RS07490 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HR071_RS07495 ENOG4105C6Z Gluconate HR071_RS07510 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HR071_RS07515 ENOG4108K5P (LipO)protein HR071_RS07530 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) HR071_RS07550 ENOG4105N0Z inner membrane protein ygbE HR071_RS07570 ENOG4108MXK alkaline phosphatase isozyme conversion HR071_RS07575 ENOG4107635 Hok Gef family protein HR071_RS07595 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase HR071_RS07600 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HR071_RS07605 ENOG4105WQV ferredoxin-like protein HR071_RS07610 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator HR071_RS07615 ENOG4105YBM electron transfer flavoprotein subunit ygcQ HR071_RS07620 ENOG4106IKH Electron transfer flavoprotein HR071_RS07625 ENOG4105C54 Major Facilitator superfamily HR071_RS07630 ENOG4107R3A FAD linked oxidase domain protein HR071_RS07635 ENOG4105CHR reductase HR071_RS07640 ENOG4108ITV Inner membrane protein yqcE HR071_RS07645 ENOG4108CWB sugar kinase ygcE HR071_RS07670 ENOG4105WBN Transcriptional regulator (LacI family HR071_RS07675 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HR071_RS07685 ENOG4105HA9 of methanol dehydrogenase type HR071_RS07700 ENOG4105DXN mazG family HR071_RS07705 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HR071_RS07710 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) HR071_RS07715 ENOG4105BZU Histidine kinase HR071_RS07720 ENOG4105EQX glucarate dehydratase HR071_RS07725 ENOG4105EQX glucarate dehydratase HR071_RS07730 ENOG4105DJB Major Facilitator Superfamily HR071_RS07735 ENOG4105QDK Flavodoxin HR071_RS07740 ENOG4105DR9 pseudouridine synthase HR071_RS07745 ENOG4105WP7 tRNA pseudouridine synthase C HR071_RS07760 ENOG4105EWT decarboxylase family HR071_RS07765 ENOG4105C44 Serine transporter HR071_RS07770 ENOG4105EJQ L-serine dehydratase HR071_RS07780 ENOG4105C0A alcohol dehydrogenase HR071_RS07785 ENOG4107W7X Aldolase HR071_RS07790 ENOG4105EDR glucose galactose transporter HR071_RS07800 ENOG4105CMG Carbohydrate kinase HR071_RS07810 ENOG4107EDW L-fucose operon activator HR071_RS07820 ENOG4105M08 Membrane HR071_RS07825 ENOG4105ETT transcriptional Regulator, LysR family HR071_RS07830 ENOG4105M5B (LipO)protein HR071_RS07835 ENOG4105C9B Cysteine desulfurase HR071_RS07840 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) HR071_RS07845 ENOG4105CUZ uba thif-type nad fad binding protein HR071_RS07850 ENOG4105CA3 membrane-bound lytic murein transglycosylase HR071_RS07880 ENOG4108ZG0 Ompa motb domain protein HR071_RS07890 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HR071_RS07985 ENOG4105F5W AtP-binding protein HR071_RS07990 ENOG4105D70 Integrase catalytic subunit HR071_RS08015 ENOG4105C2X Arabinose 5-phosphate isomerase HR071_RS08020 ENOG4105C87 Aminotransferase class I and II HR071_RS08025 ENOG4105CI1 PTS System HR071_RS08030 ENOG4105CID antiterminator HR071_RS08035 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HR071_RS08040 ENOG4108EKC n-acetylglutamate synthase HR071_RS08045 ENOG4107QYX exodeoxyribonuclease v alpha HR071_RS08050 ENOG4107QKA exodeoxyribonuclease V beta HR071_RS08055 ENOG4107QXK peptidase HR071_RS08060 ENOG4105DSY exodeoxyribonuclease V, gamma HR071_RS08065 ENOG4105RVB Prepilin peptidase dependent protein c HR071_RS08070 ENOG4105SEN Protein of unknown function (DUF2509) HR071_RS08075 ENOG4105JCS prepilin peptidase dependent protein HR071_RS08080 ENOG4105IPU prepilin peptidase dependent protein A HR071_RS08095 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HR071_RS08110 ENOG4105EE5 Membrane protein terC HR071_RS08115 ENOG4105SUV lipoprotein YgdR HR071_RS08120 ENOG4105CPC Aldo Keto reductase HR071_RS08135 ENOG41060NJ transcriptional regulator HR071_RS08145 ENOG4105RQF LysR family Transcriptional regulator HR071_RS08155 ENOG4107QNK )-transporter HR071_RS08160 ENOG4105CHR reductase HR071_RS08170 ENOG4105CHU acetyl-coa acetyltransferase HR071_RS08175 ENOG4108MHD transport protein HR071_RS08185 ENOG4108K5P (LipO)protein HR071_RS08190 ENOG4105C7W Xanthine dehydrogenase HR071_RS08195 ENOG4108HR6 Dehydrogenase HR071_RS08200 ENOG4108UTP (2Fe-2S)-binding domain protein HR071_RS08205 ENOG4108JUB Transcriptional regulator HR071_RS08210 ENOG4105IW6 Carbamoyltransferase HR071_RS08215 ENOG4107RCH Diaminopropionate ammonia-lyase HR071_RS08220 ENOG4107S4Y M20 DapE family protein YgeY HR071_RS08225 ENOG4105CD3 dihydroorotase HR071_RS08230 ENOG4105C5B carbamate kinase HR071_RS08235 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family HR071_RS08240 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC HR071_RS08245 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase HR071_RS08250 ENOG4105BZ8 glutamate synthase HR071_RS08255 ENOG4107UUR Chlorohydrolase aminohydrolase HR071_RS08260 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase HR071_RS08265 ENOG4105C7W Xanthine dehydrogenase HR071_RS08270 ENOG4105C2W permease HR071_RS08275 ENOG4107QUY Guanine deaminase HR071_RS08280 ENOG4105C7N Xanthine uracil vitamin C permease HR071_RS08285 ENOG4108R8B oxidoreductase Fe-S subunit HR071_RS08290 ENOG4105BZ8 glutamate synthase HR071_RS08295 ENOG4105C2W permease HR071_RS08315 ENOG4105CRK lysyL-tRNA synthetase HR071_RS08325 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HR071_RS08330 ENOG4105T95 Thiol disulfide interChange protein HR071_RS08335 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HR071_RS08340 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) HR071_RS08345 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB HR071_RS08350 ENOG4105Y75 tpr repeat protein HR071_RS08355 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) HR071_RS08360 ENOG4108UT2 hemolysin iii HR071_RS08370 ENOG4105CS2 ec 3.2.1.21 HR071_RS08395 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HR071_RS08400 ENOG4105D0A hydroxylase HR071_RS08405 ENOG4107RAQ aminopeptidase HR071_RS08425 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HR071_RS08435 ENOG4108JQ1 Dehydrogenase HR071_RS08455 ENOG4105D5P Methylmalonyl-coA mutase HR071_RS08465 ENOG4105MPN Membrane HR071_RS08470 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HR071_RS08475 ENOG4105D64 Mechanosensitive ion channel HR071_RS08480 ENOG4105D2N Aldolase HR071_RS08515 ENOG4108JJB ABC transporter HR071_RS08520 ENOG4107Z1W Fructose transport system kinase HR071_RS08525 ENOG4108R4K DNA-binding, transcriptional regulator HR071_RS08530 ENOG4108Q8A Fructose-1,6-bisphosphatase HR071_RS08535 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HR071_RS08540 ENOG4105CTS PTS system mannitol-specific HR071_RS08545 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia HR071_RS08550 ENOG4105EPW hflc protein HR071_RS08555 ENOG4105CV1 Transketolase (EC 2.2.1.1) HR071_RS08560 ENOG4108K0D peptidase, M48 HR071_RS08575 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) HR071_RS08595 ENOG4107QNK )-transporter HR071_RS08605 ENOG4105RWS endonuclease I HR071_RS08610 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HR071_RS08615 ENOG4105D7Z glutathione synthase HR071_RS08630 ENOG4105CZX twitching motility protein HR071_RS08635 ENOG4105DFA alanine racemase domain protein HR071_RS08640 ENOG4108VIA integral membrane protein HR071_RS08650 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) HR071_RS08655 ENOG4105CSA Coproporphyrinogen iii oxidase HR071_RS08660 ENOG4106MH3 alpha helix chain HR071_RS08665 ENOG4105HDK L-asparaginase HR071_RS08670 ENOG4105K33 Periplasmic Protein HR071_RS08675 ENOG41090ED Protein with unknown function (DUF469) HR071_RS08685 ENOG4105CEN a g-specific adenine glycosylase HR071_RS08690 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) HR071_RS08700 ENOG4105EAA nucleoside HR071_RS08705 ENOG4105CXN decarboxylase HR071_RS08710 ENOG4108UQV Membrane HR071_RS08730 ENOG4105EQR Transposase IS116 IS110 IS902 HR071_RS08750 ENOG4108YXQ IS66 Orf2 family protein HR071_RS08765 ENOG4105ES5 Histidine kinase HR071_RS08770 ENOG4105DPZ Two component transcriptional regulator (Winged helix family HR071_RS08780 ENOG4105EQW The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) HR071_RS08790 ENOG4108RC6 RTX toxin HR071_RS08795 ENOG4107V48 Hemolysin-type calcium-binding HR071_RS08800 ENOG4108JJA ABC, transporter HR071_RS08805 ENOG4105C42 Type I secretion membrane fusion protein (HlyD HR071_RS08820 ENOG4108YXQ IS66 Orf2 family protein HR071_RS08840 ENOG41067TZ transcriptional regulator, MarR family HR071_RS08860 ENOG4106CXJ Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR HR071_RS08870 ENOG4106P2F Pfam:Pili_assembly_C HR071_RS08875 ENOG4106PG1 outer membrane usher protein HR071_RS08880 ENOG4108ZJG MrfB protein HR071_RS08885 ENOG4105HMV Fimbrial protein HR071_RS08905 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 HR071_RS08950 ENOG4105D05 Receptor HR071_RS08970 ENOG4108YXQ IS66 Orf2 family protein HR071_RS08985 ENOG4105I1J Autotransporter HR071_RS09020 ENOG4108S55 polysaccharide biosynthesis protein HR071_RS09025 ENOG4106FPV ATP-binding protein YghR HR071_RS09030 ENOG4108NDC ATP-binding protein yghS HR071_RS09035 ENOG4108GH0 ATP-binding protein yghT HR071_RS09040 ENOG4105CJ3 phosphate transporter HR071_RS09045 ENOG4106032 Glutathionylspermidine synthase HR071_RS09050 ENOG4105CYM Glutathione S-transferase HR071_RS09055 ENOG41082MF Hydrogenase assembly chaperone hypC hupF HR071_RS09060 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) HR071_RS09065 ENOG4108WGS hydrogenase 2-specific chaperone HR071_RS09070 ENOG4108USZ hydrogenase HR071_RS09075 ENOG4105DPX Hydrogenase, large subunit HR071_RS09080 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit HR071_RS09085 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HR071_RS09090 ENOG4105E3S small subunit HR071_RS09095 ENOG410900S Protein of unknown function (DUF2623) HR071_RS09105 ENOG4105CPC Aldo Keto reductase HR071_RS09115 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HR071_RS09120 ENOG4108ZZF transport protein (ExbD) HR071_RS09125 ENOG4105CWK Biopolymer transport protein, ExbB HR071_RS09130 ENOG4105C28 cystathionine HR071_RS09135 ENOG4108K81 inner membrane protein YghB HR071_RS09140 ENOG4105CF7 AraC family transcriptional regulator HR071_RS09145 ENOG4108I6A alcohol dehydrogenase HR071_RS09150 ENOG4105CV8 reductase HR071_RS09155 ENOG4105ZKC Conserved Protein HR071_RS09165 ENOG4105CCT upf0313 protein HR071_RS09170 ENOG4107YCY Transcriptional regulator HR071_RS09175 ENOG4105DEI Mannitol dehydrogenase HR071_RS09180 ENOG4105CPQ Dehydrogenase HR071_RS09185 ENOG4105DG4 malate L-lactate dehydrogenase HR071_RS09190 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HR071_RS09200 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HR071_RS09205 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) HR071_RS09210 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase HR071_RS09215 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HR071_RS09220 ENOG4108J59 Extracellular solute-binding protein, family 5 HR071_RS09225 ENOG4105F4I Transcriptional regulator HR071_RS09230 ENOG4105H4F exported protein HR071_RS09235 ENOG4105XJC Two component transcriptional regulator (Winged helix family HR071_RS09240 ENOG4105DHQ Histidine kinase HR071_RS09245 ENOG4107DEU Inner membrane protein YgiZ HR071_RS09255 ENOG4105NF4 modulator of drug activity HR071_RS09260 ENOG4105VRH Antibiotic biosynthesis monooxygenase HR071_RS09265 ENOG4106KNT transcriptional regulator HR071_RS09275 ENOG4105EHG Permease protein HR071_RS09280 ENOG4105DQ5 transport system permease protein HR071_RS09285 ENOG4105E0A ABC, transporter HR071_RS09295 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HR071_RS09300 ENOG4105IPS esterase HR071_RS09305 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HR071_RS09310 ENOG4108SX3 cytoplasmic protein HR071_RS09315 ENOG41087AY ADP-Ribose pyrophosphatase HR071_RS09320 ENOG4105DFG type I secretion outer membrane protein HR071_RS09330 ENOG4106032 Glutathionylspermidine synthase HR071_RS09335 ENOG4108MR7 Arylsulfotransferase HR071_RS09340 ENOG4108N92 Thiol disulfide Interchange Protein HR071_RS09350 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HR071_RS09365 ENOG4105H8W Fimbrial protein HR071_RS09375 ENOG4108TTM chaperone HR071_RS09380 ENOG4108MY7 Fimbrial HR071_RS09390 ENOG4105W0Z cytoplasmic protein HR071_RS09400 ENOG4105PV3 Inner membrane protein yqiJ HR071_RS09405 ENOG4107S78 Band 7 protein HR071_RS09425 ENOG4105I7R Adenylate cyclase HR071_RS09430 ENOG4106MWK domain protein HR071_RS09445 ENOG4107ZVW dihydroneopterin aldolase HR071_RS09460 ENOG4106DSS Tartrate dehydratase subunit alpha HR071_RS09465 ENOG4107GFK fumarate HR071_RS09470 ENOG4107QPK )-transporter HR071_RS09485 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HR071_RS09490 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HR071_RS09505 ENOG4105Q26 Siderophore-interacting protein HR071_RS09510 ENOG4105NTW Transcriptional regulator HR071_RS09515 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor HR071_RS09525 ENOG4108Y51 tRNA-binding protein HR071_RS09530 ENOG4105CQ4 Transcriptional regulator HR071_RS09535 ENOG4105CNT hydrolase family 2 HR071_RS09540 ENOG4105FK9 beta-D-galactosidase beta subunit HR071_RS09545 ENOG4105E5D amino acid HR071_RS09550 ENOG4107W6W Conserved Protein HR071_RS09555 ENOG4107WCA isomerase HR071_RS09560 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HR071_RS09565 ENOG4108Z3N Transcriptional regulator HR071_RS09570 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase HR071_RS09580 ENOG4108VKG metal-dependent hydrolase HR071_RS09585 ENOG4108UB4 uncharacterized protein ygjQ HR071_RS09590 ENOG4105EE0 oxidoreductase HR071_RS09595 ENOG4105DU1 integral membrane protein, terc HR071_RS09605 ENOG4105P66 Membrane HR071_RS09610 ENOG4105CTX dehydratase HR071_RS09620 ENOG4105DPW Major facilitator superfamily MFS_1 HR071_RS09625 ENOG4107YCY Transcriptional regulator HR071_RS09630 ENOG4106W5V Membrane HR071_RS09635 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) HR071_RS09640 ENOG4105WAY exported protein HR071_RS09645 ENOG4105NE1 Conserved Protein HR071_RS09650 ENOG41090KG Inner membrane protein YqjE HR071_RS09655 ENOG4105YJD HR071_RS09660 ENOG4108VBZ doxx family HR071_RS09665 ENOG4105CHF Glutathione S-transferase HR071_RS09670 ENOG4105KAF membrAne HR071_RS09675 ENOG4105CWB LysR family transcriptional Regulator HR071_RS09680 ENOG4108CNN domain protein HR071_RS09685 ENOG4106D80 Uncharacterized protein YhaL HR071_RS09695 ENOG4105C44 Serine transporter HR071_RS09700 ENOG4105EJQ L-serine dehydratase HR071_RS09705 ENOG4105KME endoribonuclease L-psp HR071_RS09710 ENOG4105C6N Formate acetyltransferase HR071_RS09725 ENOG4105C7B Threonine dehydratase HR071_RS09730 ENOG410811B TRANSCRIPTIONal HR071_RS09745 ENOG4105BZW Glycerate kinase HR071_RS09750 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HR071_RS09760 ENOG4105DJB Major Facilitator Superfamily HR071_RS09765 ENOG4105CTX dehydratase HR071_RS09770 ENOG4105ZEG Suppressor protein HR071_RS09775 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression HR071_RS09780 ENOG4105E98 transcriptional regulator DeoR family HR071_RS09790 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB HR071_RS09800 ENOG4105F3R pts system mannose fructose sorbose family iid HR071_RS09805 ENOG4108YTN IIa component HR071_RS09810 ENOG4105CE4 GlcNAc 6-P deacetylase HR071_RS09815 ENOG4105E70 isomerase HR071_RS09825 ENOG4108UZY PTS System HR071_RS09830 ENOG4105ETZ PTS System HR071_RS09835 ENOG4105F3R pts system mannose fructose sorbose family iid HR071_RS09840 ENOG4106HBN Galactosamine-6-phosphate isomerase HR071_RS09845 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HR071_RS09865 ENOG4105W4M Transport-associated protein HR071_RS09870 ENOG4107S21 permease HR071_RS09875 ENOG4105K4T epimerase HR071_RS09880 ENOG4107R7Y intracellular protease Pfpi family HR071_RS09895 ENOG4108YYD acetyltransferase HR071_RS09915 ENOG4105DEN Luciferase family HR071_RS09920 ENOG4105CIC tryptophan-specific transport protein HR071_RS09925 ENOG4105C1J atp-dependent rna helicase HR071_RS09965 ENOG4105CHV Transcription elongation factor NusA HR071_RS09985 ENOG4105DIJ Phosphoethanolamine transferase HR071_RS09995 ENOG4105NTZ Preprotein translocase subunit SecG HR071_RS10005 ENOG4105EEI dihydropteroate synthase HR071_RS10010 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HR071_RS10020 ENOG4105HBR Rna-binding protein HR071_RS10025 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) HR071_RS10030 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase HR071_RS10040 ENOG4105QYV Membrane HR071_RS10055 ENOG4105EAH synthase HR071_RS10060 ENOG4105HVQ Regulatory factor of maltose metabolism HR071_RS10070 ENOG4105VFK BolA family HR071_RS10075 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane HR071_RS10080 ENOG4105E3I toluene tolerance HR071_RS10085 ENOG4107PE3 Mammalian cell entry related domain protein HR071_RS10090 ENOG4105CY3 ABC transporter, permease HR071_RS10095 ENOG4105DHJ ABC, transporter HR071_RS10100 ENOG4105FEU K -dependent Na -Ca exchanger HR071_RS10105 ENOG4105C2X Arabinose 5-phosphate isomerase HR071_RS10115 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) HR071_RS10120 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HR071_RS10125 ENOG4108IUZ ABC transporter HR071_RS10130 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HR071_RS10135 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA HR071_RS10140 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN HR071_RS10150 ENOG41080Z8 PHOSPHOCARRIER protein HR071_RS10155 ENOG4108NIH transferase activity, transferring phosphorus-containing groups HR071_RS10165 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain HR071_RS10170 ENOG4105BZU Histidine kinase HR071_RS10175 ENOG4105N5T Radical SAM Protein HR071_RS10180 ENOG4105CBC glutamate synthase HR071_RS10185 ENOG4105BZ8 glutamate synthase HR071_RS10190 ENOG4108R66 Conserved Protein HR071_RS10195 ENOG41061DF Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity) HR071_RS10205 ENOG4105JHE Major Facilitator Superfamily HR071_RS10215 ENOG4108QBF Transcriptional regulator HR071_RS10220 ENOG4105KB2 stringent starvation protein b HR071_RS10225 ENOG4107MKT Stringent starvation protein a HR071_RS10240 ENOG4105D6Z AFG1 family ATPase HR071_RS10245 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III HR071_RS10250 ENOG4105C0H protease HR071_RS10255 ENOG4105C0H protease HR071_RS10270 ENOG4105RID UPF0379 protein yhcN HR071_RS10275 ENOG4105UNR (Barnase) inhibitor HR071_RS10290 ENOG4105ZQC membrane protein AaeX HR071_RS10295 ENOG4105CR8 Transcriptional regulator HR071_RS10300 ENOG4105D1U peptidase U62 modulator of DNA gyrase HR071_RS10305 ENOG4105QD6 exported protein HR071_RS10310 ENOG4105C03 ribonuclease HR071_RS10315 ENOG4108Z03 MAF-like protein HR071_RS10320 ENOG4105VQ7 Rod shape-determining protein MreD HR071_RS10325 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HR071_RS10335 ENOG41062P1 Diguanylate cyclase phosphodiesterase HR071_RS10340 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HR071_RS10345 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HR071_RS10350 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HR071_RS10360 ENOG4107UEK pfkb domain protein HR071_RS10365 ENOG4105CNN ABC, transporter HR071_RS10370 ENOG4105C2J ABC transporter HR071_RS10375 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HR071_RS10380 ENOG4105D2N Aldolase HR071_RS10385 ENOG4105E98 transcriptional regulator DeoR family HR071_RS10390 ENOG4107UEK pfkb domain protein HR071_RS10395 ENOG4105RG0 Membrane HR071_RS10400 ENOG4108IA2 Sodium pantothenate symporter HR071_RS10410 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HR071_RS10420 ENOG4105CEC DNA methylase N-4 N-6 HR071_RS10425 ENOG41061ME transport protein HR071_RS10430 ENOG4108XG4 DNA-binding transcriptional regulator HR071_RS10435 ENOG4105C1P efflux transporter, rnd family, mfp subunit HR071_RS10440 ENOG4105BZS acriflavin resistance protein HR071_RS10445 ENOG4105XCM membrane LIPOPROTEIN HR071_RS10455 ENOG4105EZ7 amino acid ABC transporter HR071_RS10460 ENOG4105DRP amino acid AbC transporter HR071_RS10465 ENOG4105CDA abc transporter atp-binding protein HR071_RS10505 ENOG4108Z0R Transferase HR071_RS10510 ENOG4105SG3 Protein of unknown function (DUF1488) HR071_RS10515 ENOG4105E2X shikimate dehydrogenase HR071_RS10520 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) HR071_RS10525 ENOG4108WI1 Dna topoisomerase HR071_RS10535 ENOG4105C79 DNA protecting protein DprA HR071_RS10555 ENOG4105C1A potassium transporter peripheral membrane HR071_RS10565 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system HR071_RS10570 ENOG4105W1Y Transcriptional regulator HR071_RS10575 ENOG4105VTS DnaJ-like, subfamily C HR071_RS10605 ENOG41067V7 50S ribosomal protein L36 HR071_RS10610 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HR071_RS10700 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) HR071_RS10720 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication HR071_RS10725 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression HR071_RS10730 ENOG4107KSE General secretion pathway protein C HR071_RS10735 ENOG4105GVR general secretion pathway protein D HR071_RS10740 ENOG4107QHF type ii secretion system protein e HR071_RS10745 ENOG4105D7Q type ii secretion system HR071_RS10750 ENOG4108VAU general secretion pathway protein G HR071_RS10755 ENOG41069X0 general secretion pathway protein h HR071_RS10770 ENOG4105R04 type II secretion system protein K HR071_RS10775 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) HR071_RS10790 ENOG4108UQY Iron-storage protein HR071_RS10795 ENOG4105W53 bacterioferritin-associated ferredoxin HR071_RS10800 ENOG4108NNZ chitinase HR071_RS10840 ENOG4105WWK YheO domain protein HR071_RS10845 ENOG4108V1T peptidylprolyl cis-trans isomerase HR071_RS10855 ENOG4108YZY peptidylprolyl cis-trans isomerase HR071_RS10860 ENOG4105VKU nucleicacid-binding protein HR071_RS10875 ENOG4105C5H ABC transporter HR071_RS10880 ENOG4105DNZ Alpha Beta Hydrolase HR071_RS10890 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) HR071_RS10895 ENOG4108UKZ OsmC family HR071_RS10905 ENOG410613R integral membrane protein, YccS YhfK family HR071_RS10910 ENOG4105C8Y Acetylornithine aminotransferase HR071_RS10915 ENOG4105DDQ anthranilate synthase HR071_RS10920 ENOG4105MZU cell filamentation protein HR071_RS10930 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HR071_RS10940 ENOG4107QZF nitrite reductase NADPH large subunit HR071_RS10945 ENOG4105WZK nitrite reductase NADPH small subunit HR071_RS10950 ENOG4107V9H nitrite transporter HR071_RS10960 ENOG4105VYH HR071_RS10965 ENOG4106PKC pyridoxal phosphate binding HR071_RS10970 ENOG4106M0N transport system permease protein HR071_RS10975 ENOG4105MUZ Protein of unknown function DUF2620 HR071_RS10980 ENOG41080QX K07048 phosphotriesterase-related protein HR071_RS10985 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) HR071_RS10990 ENOG4108626 Racemase HR071_RS10995 ENOG4105RMW regulation of transcription, DNA-dependent HR071_RS11000 ENOG4108M21 HR071_RS11005 ENOG4105C31 Tryptophanyl-tRNA synthetase HR071_RS11010 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HR071_RS11015 ENOG4105DJV ribulose-phosphate 3-epimerase HR071_RS11020 ENOG4105DFE Dna adenine methylase HR071_RS11025 ENOG4105EGB membrane protein DamX HR071_RS11040 ENOG4105E4G Type IV pilus HR071_RS11045 ENOG4105ITY Required for the use of extracellular DNA as a nutrient HR071_RS11050 ENOG4105XPX DNA utilization protein HofO HR071_RS11055 ENOG41065NF Fimbrial assembly family protein HR071_RS11060 ENOG4108U1Q Pilus assembly protein HR071_RS11065 ENOG4108JQC penicillin-binding protein 1A HR071_RS11070 ENOG4107RK2 ADP-ribose diphosphatase NudE HR071_RS11075 ENOG4105DQY intracellular growth attenuator HR071_RS11080 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HR071_RS11085 ENOG4105VEJ Heat shock protein HR071_RS11095 ENOG4105D7V transposase HR071_RS11105 ENOG4108MAJ Membrane HR071_RS11115 ENOG4105E0F Histidine kinase HR071_RS11125 ENOG4108RRZ Transcription elongation factor GreB HR071_RS11130 ENOG4105BZM domain protein HR071_RS11135 ENOG4105XFK Ferrous iron transport protein A HR071_RS11140 ENOG4105CE1 Ferrous iron transport protein b HR071_RS11150 ENOG4105DNE Transposase HR071_RS11155 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) HR071_RS11160 ENOG4105MJ2 Competence protein HR071_RS11170 ENOG4105C6Z Gluconate HR071_RS11175 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) HR071_RS11180 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HR071_RS11195 ENOG4105CYB regulatoR HR071_RS11200 ENOG4105E98 transcriptional regulator DeoR family HR071_RS11215 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HR071_RS11235 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) HR071_RS11250 ENOG4108IUM Glycogen debranching enzyme HR071_RS11260 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) HR071_RS11265 ENOG41076UM multiple antibiotic resistance (MarC)-related protein HR071_RS11275 ENOG4105C9U ATP-dependent DNA helicase RecQ HR071_RS11280 ENOG4105C6Z Gluconate HR071_RS11285 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HR071_RS11290 ENOG4105DIQ Transcriptional regulator HR071_RS11295 ENOG4105C2I pirin domain protein HR071_RS11300 ENOG4105D9R oxidoreductase HR071_RS11305 ENOG4105WCN acetyltransferase HR071_RS11310 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HR071_RS11315 ENOG4105WC8 Conserved Protein HR071_RS11320 ENOG4107T6V glycerophosphoryl diester phosphodiesterase HR071_RS11340 ENOG4105BZ7 extracellular solute-binding protein family 1 HR071_RS11345 ENOG4108IV0 ABC, transporter HR071_RS11350 ENOG4105C0Z ABC transporter HR071_RS11355 ENOG4105CF8 branched-chain amino acid ABC transporter, permease HR071_RS11360 ENOG4105C32 Amino acid ABC transporter (Permease) HR071_RS11365 ENOG4105CP9 extracellular ligand-binding receptor HR071_RS11370 ENOG4105U59 -acetyltransferase HR071_RS11385 ENOG4105CP9 extracellular ligand-binding receptor HR071_RS11390 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HR071_RS11395 ENOG4105CRP Part of the ABC transporter FtsEX involved in HR071_RS11400 ENOG4105CAK Cell division ATP-binding protein ftsE HR071_RS11405 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HR071_RS11410 ENOG4106H78 methyltransferase HR071_RS11415 ENOG4105MG3 Membrane HR071_RS11425 ENOG4107FS9 Membrane HR071_RS11440 ENOG4105EX9 Membrane HR071_RS11445 ENOG4108W1V Lipoprotein HR071_RS11450 ENOG4105F9N Major Facilitator Superfamily HR071_RS11455 ENOG4105DSF transport protein HR071_RS11460 ENOG4107YAK holo-(acyl carrier protein) synthase 2 HR071_RS11465 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein HR071_RS11470 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HR071_RS11475 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HR071_RS11480 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HR071_RS11485 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) HR071_RS11505 ENOG41090UW PTS System HR071_RS11510 ENOG4105DT3 PTS system, galactitol-specific IIc component HR071_RS11525 ENOG4105D2N Aldolase HR071_RS11530 ENOG4105CMI transporter HR071_RS11535 ENOG4105CJ1 ABC, transporter HR071_RS11540 ENOG4105D0S secretion protein (HlyD HR071_RS11545 ENOG4107UNS conserved inner membrane protein HR071_RS11550 ENOG4105CBX hi0933 family HR071_RS11555 ENOG4105CJ3 phosphate transporter HR071_RS11570 ENOG4105DUX Transporter HR071_RS11580 ENOG4105DGW oligopeptidase A HR071_RS11585 ENOG4105D6S protein involved in catabolism of external DNA HR071_RS11590 ENOG4105DC8 reductase HR071_RS11600 ENOG4105K89 arsenate reductase HR071_RS11610 ENOG4105Y4Z Outer Membrane Lipoprotein HR071_RS11620 ENOG4106QJH hemin transport protein HR071_RS11625 ENOG4107ENK receptor HR071_RS11635 ENOG4105D4P Coproporphyrinogen iii oxidase HR071_RS11640 ENOG41090JE Utilization Protein HR071_RS11650 ENOG4105EHG Permease protein HR071_RS11655 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) HR071_RS11660 ENOG4105KT7 mgtC SapB transporter HR071_RS11665 ENOG4105XXV Acid-resistance protein HR071_RS11670 ENOG41060V2 Acid-resistance protein HR071_RS11675 ENOG4108YK4 Acid-resistance membrane protein HR071_RS11680 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci HR071_RS11690 ENOG4105C1P efflux transporter, rnd family, mfp subunit HR071_RS11695 ENOG4105BZS acriflavin resistance protein HR071_RS11700 ENOG4105D3F AraC Family Transcriptional Regulator HR071_RS11705 ENOG4108NKV transcriptional regulator HR071_RS11710 ENOG4105CVK Glutamate decarboxylase HR071_RS11715 ENOG4105CA0 peroxidase HR071_RS11725 ENOG4106S2D Transcriptional regulator HR071_RS11730 ENOG4105CBN LysR family transcriptional regulator HR071_RS11735 ENOG4107H3J ribonuclease HR071_RS11740 ENOG4105CSH Transporter HR071_RS11745 ENOG41066T0 asmA family HR071_RS11750 ENOG4105CMB EAL domain-containing protein HR071_RS11755 ENOG4107SS6 2-dehydro-3-deoxygluconokinase HR071_RS11760 ENOG4105CS0 peptidase HR071_RS11770 ENOG4105BZU Histidine kinase HR071_RS11775 ENOG4105EJG cellulose synthase HR071_RS11780 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) HR071_RS11785 ENOG4107EEX Cellulose synthase regulator protein HR071_RS11790 ENOG4107QZ7 Cellulose synthase catalytic subunit HR071_RS11800 ENOG410661M cytoplasmic protein HR071_RS11805 ENOG4105U74 cellulose biosynthesis protein BcsE HR071_RS11810 ENOG4105WQA Cellulose biosynthesis protein BcsF HR071_RS11815 ENOG4105D1V cellulose synthase operon protein YhjU HR071_RS11835 ENOG4105C44 Serine transporter HR071_RS11840 ENOG4108JQ7 (ABC) transporter HR071_RS11845 ENOG4105C3U ABC transporter HR071_RS11850 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HR071_RS11855 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HR071_RS11860 ENOG4105DEF Extracellular solute-binding protein, family 5 HR071_RS11870 ENOG4105DIJ Phosphoethanolamine transferase HR071_RS11875 ENOG4105FCD Major Facilitator HR071_RS11880 ENOG4105EAX Putative lipase HR071_RS11885 ENOG4108R3E Dna-3-methyladenine glycosylase i HR071_RS11890 ENOG4105HNP -acetyltransferase HR071_RS11895 ENOG4107QY8 reductase HR071_RS11900 ENOG4108ZG0 Ompa motb domain protein HR071_RS11910 ENOG4106JH6 (LipO)protein HR071_RS11915 ENOG4105MVF Transcriptional regulator HR071_RS11925 ENOG41060TC Hok gef cell toxic protein HR071_RS11945 ENOG4105MEV Acyl-transferase HR071_RS11950 ENOG4108Z12 YiaAB two helix domain-containing protein HR071_RS11955 ENOG410688U Inner membrane protein yiaB HR071_RS11960 ENOG4105CMG Carbohydrate kinase HR071_RS11970 ENOG4105DFW ABC transporter HR071_RS11975 ENOG4105C2J ABC transporter HR071_RS11980 ENOG4108HWW ABC transporter HR071_RS11985 ENOG4105T16 Transcriptional regulator (AraC family) HR071_RS11990 ENOG4108UR8 BAX protein HR071_RS11995 ENOG4107T9C Alpha amylase catalytic region HR071_RS12000 ENOG4105JKW Valine--pyruvate aminotransferase HR071_RS12005 ENOG4108XIB electron transport protein ysaA HR071_RS12010 ENOG4105J4Q Transcriptional regulator HR071_RS12020 ENOG4108R66 Conserved Protein HR071_RS12025 ENOG4108M5W HR071_RS12030 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter HR071_RS12035 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HR071_RS12040 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HR071_RS12045 ENOG4105CMG Carbohydrate kinase HR071_RS12050 ENOG4105H6Q decarboxylase HR071_RS12055 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase HR071_RS12060 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HR071_RS12070 ENOG4105CT4 transporter HR071_RS12080 ENOG4105C26 Dehydrogenase HR071_RS12090 ENOG4105C0A alcohol dehydrogenase HR071_RS12095 ENOG4105EM7 Selenocysteine-specific translation elongation factor HR071_RS12105 ENOG4108U78 Glutathione S-transferase HR071_RS12110 ENOG4105EFX secretion protein, HlyD family HR071_RS12115 ENOG4105FP6 Protein of unknown function (DUF3302) HR071_RS12120 ENOG4105CTS PTS system mannitol-specific HR071_RS12130 ENOG4105E61 Mannitol repressor protein HR071_RS12135 ENOG41060ND LF82 chromosome, complete sequence HR071_RS12140 ENOG4108YYI Protein of unknown function (DUF2810) HR071_RS12145 ENOG4108WY4 inner membrane lipoprotein HR071_RS12155 ENOG4105DAA L-lactate HR071_RS12160 ENOG41073TP transcriptional regulator HR071_RS12170 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HR071_RS12175 ENOG4105D7W serine acetyltransferase HR071_RS12190 ENOG4105VW4 glutaredoxin 3 HR071_RS12195 ENOG4107YZP Rhodanese domain protein HR071_RS12205 ENOG41063SB peptidase HR071_RS12210 ENOG4105PXI polysaccharide deacetylase HR071_RS12215 ENOG4105K64 Glycosyl transferase, family 2 HR071_RS12225 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HR071_RS12235 ENOG4105XA0 heptosyltransferase ii HR071_RS12240 ENOG4105D16 lipopolysaccharide heptosyltransferase i HR071_RS12245 ENOG41068PG O-Antigen polymerase HR071_RS12250 ENOG4108XNZ glycosyl transferase HR071_RS12255 ENOG4108QD8 lipopolysaccharide core biosynthesis protein HR071_RS12260 ENOG4108PDR lipopolysaccharide core biosynthesis protein HR071_RS12265 ENOG4105X1N Glycosyl transferase family 8 HR071_RS12270 ENOG4106AH0 Glycosyl Transferase HR071_RS12275 ENOG4107XU6 Glycosyl transferase (Group 1 HR071_RS12280 ENOG410650X lipopolysaccharide core region biosynthetic process HR071_RS12285 ENOG4107543 (lipo)polysaccharide HR071_RS12290 ENOG4107RJ7 Glycosyl transferase (Group 1 HR071_RS12295 ENOG4105DKP glycosyl transferase, family 9 HR071_RS12300 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HR071_RS12320 ENOG4105KDC 50s ribosomal protein l28 HR071_RS12330 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HR071_RS12335 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) HR071_RS12355 ENOG4105DSJ YicC domain protein HR071_RS12470 ENOG4105EN6 Membrane HR071_RS12475 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) HR071_RS12480 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HR071_RS12490 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HR071_RS12495 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase HR071_RS12500 ENOG4105CB5 ATP-dependent DNA helicase recG HR071_RS12505 ENOG4105D6U Sodium Glutamate Symporter HR071_RS12510 ENOG4105C2W permease HR071_RS12515 ENOG4105JV1 AsmA family HR071_RS12525 ENOG4105DKQ ROK family HR071_RS12535 ENOG4105D2N Aldolase HR071_RS12540 ENOG4105DM4 PTS System HR071_RS12545 ENOG4108YRF PTS System HR071_RS12550 ENOG4105DM4 PTS System HR071_RS12555 ENOG4105ETD TRANSCRIPTIONal HR071_RS12560 ENOG4105CJQ hydrolase, family 31 HR071_RS12565 ENOG4105CT4 transporter HR071_RS12585 ENOG4105DIJ Phosphoethanolamine transferase HR071_RS12605 ENOG4105T40 surface antigen msp4 family protein HR071_RS12640 ENOG4107SCJ type I restriction enzyme EcoKI subunit R HR071_RS12655 ENOG4105M03 Domain of unknown function (DUF955) HR071_RS12730 ENOG4105TS0 gtp-binding protein HR071_RS12735 ENOG4108KZE transcriptional regulator HR071_RS12750 ENOG4106H6R UPF0380 protein HR071_RS12755 ENOG4106549 Antirestriction protein HR071_RS12760 ENOG4108YGG dna repair protein HR071_RS12770 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HR071_RS12800 ENOG4108UZ3 Transporter HR071_RS12805 ENOG4105D01 (LipO)protein HR071_RS12810 ENOG4105T8A Uncharacterized protein YicS HR071_RS12830 ENOG4108SAJ Protein of unknown function (DUF1198) HR071_RS12835 ENOG4105C7N Xanthine uracil vitamin C permease HR071_RS12845 ENOG4105CXY transporter HR071_RS12850 ENOG4105CXY transporter HR071_RS12855 ENOG4105BZU Histidine kinase HR071_RS12860 ENOG4108KX4 response regulator HR071_RS12870 ENOG4105M71 acetolactate synthase 1 regulatory subunit HR071_RS12875 ENOG4105C7K acetolactate synthase HR071_RS12885 ENOG4105E5M Multidrug resistance protein D HR071_RS12890 ENOG4105J13 transcriptional regulator HR071_RS12895 ENOG4105JP4 Inner membrane protein yidG HR071_RS12900 ENOG4105VG5 Membrane HR071_RS12910 ENOG4107RUZ Sss sodium solute transporter superfamily HR071_RS12915 ENOG4108AHD Transcriptional regulator HR071_RS12935 ENOG4105R2A (LipO)protein HR071_RS12940 ENOG4105D99 atp gtp-binding protein HR071_RS12950 ENOG4105DJB Major Facilitator Superfamily HR071_RS12960 ENOG4108RTU Aldolase HR071_RS12965 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HR071_RS12970 ENOG4105EMF GntR family transcriptional regulator HR071_RS12975 ENOG410657R replicase EC 2.7 HR071_RS12980 ENOG410667J hydrolase HR071_RS12985 ENOG4105VP5 Bacterial protein of unknown function (DUF937) HR071_RS12990 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HR071_RS13000 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HR071_RS13015 ENOG4105VG0 50S ribosomal protein l34 HR071_RS13050 ENOG4108P6C Tryptophan transporter of low affinity HR071_RS13055 ENOG4105CNH Multidrug resistance protein MdtL HR071_RS13060 ENOG4105G2Y Transcriptional regulator HR071_RS13065 ENOG4105E8Q phosphopantetheinyl transferase HR071_RS13070 ENOG4108YYH Nadph-dependent fmn reductase HR071_RS13075 ENOG4105C7N Xanthine uracil vitamin C permease HR071_RS13080 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 HR071_RS13085 ENOG4106HGK Inner membrane protein yieI HR071_RS13090 ENOG4106611 bacteriocin immunity HR071_RS13095 ENOG4107VKM 6-phosphogluconolactonase HR071_RS13100 ENOG4105DYC esterase HR071_RS13105 ENOG4108P68 Outer membrane porin HR071_RS13110 ENOG4105CS2 ec 3.2.1.21 HR071_RS13115 ENOG4105C5Y PTS System HR071_RS13125 ENOG4108UTW Plays a role in the regulation of phosphate uptake HR071_RS13130 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HR071_RS13135 ENOG4105E2Z phosphate ABC transporter (Permease HR071_RS13140 ENOG4105C8U phosphate abc transporter HR071_RS13145 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) HR071_RS13150 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HR071_RS13155 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) HR071_RS13200 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation HR071_RS13215 ENOG4105QTB Flavodoxin HR071_RS13220 ENOG4108VVK transcriptional Regulator, AsnC HR071_RS13255 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) HR071_RS13260 ENOG4105C2J ABC transporter HR071_RS13265 ENOG4105CNN ABC, transporter HR071_RS13270 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HR071_RS13275 ENOG4108RVA ribokinase HR071_RS13280 ENOG4105ETE Transcriptional regulator (LacI family HR071_RS13285 ENOG4105C0R drug resistance transporter emrb qaca subfamily HR071_RS13290 ENOG4107EJG GntR family transcriptional regulator HR071_RS13330 ENOG4108WFC UPF0438 protein yifE HR071_RS13335 ENOG4105C0P Mg chelatase subunit ChlI HR071_RS13355 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit HR071_RS13360 ENOG4105CM2 brancheD-chain amino acid aminotransferase HR071_RS13370 ENOG4105C7B Threonine dehydratase HR071_RS13375 ENOG4105EMY transcriptional regulator HR071_RS13385 ENOG4105KQ5 peptidylprolyl cis-trans isomerase HR071_RS13390 ENOG4105C4R Atp-dependent dna helicase HR071_RS13415 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HR071_RS13420 ENOG4105ESV Glycosyl transferase, family 4 HR071_RS13425 ENOG4105SFE lipopolysaccharide biosynthesis protein HR071_RS13430 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase HR071_RS13435 ENOG4107QQG Dehydrogenase HR071_RS13440 ENOG4105C1B dTDP-glucose 4-6-dehydratase HR071_RS13445 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HR071_RS13450 ENOG4108WJ1 acetyltransferase HR071_RS13455 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase HR071_RS13460 ENOG4105EGZ biosynthesis protein HR071_RS13465 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) HR071_RS13480 ENOG4105C85 amino acid HR071_RS13505 ENOG4105C4X radical SAM domain protein HR071_RS13510 ENOG4105ENH Sulfatase HR071_RS13520 ENOG410601J HemY protein HR071_RS13525 ENOG4105ECF c-methyltransferase HR071_RS13530 ENOG41076E6 Uroporphyrinogen-III Synthase HR071_RS13535 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) HR071_RS13540 ENOG4107T0K Adenylate cyclase HR071_RS13555 ENOG4105S7Z (LipO)protein HR071_RS13565 ENOG4105CT0 Protein of unknown function, DUF484 HR071_RS13575 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant HR071_RS13580 ENOG4105C4R Atp-dependent dna helicase HR071_RS13585 ENOG4107V4F S-adenosyl-l-methionine hydroxide adenosyltransferase HR071_RS13590 ENOG4108T58 Mg2 transport protein CorA HR071_RS13595 ENOG4107QUT magnesium and cobalt transport protein CorA HR071_RS13600 ENOG4105NRM Membrane HR071_RS13605 ENOG4106WR8 Inner membrane protein YigG HR071_RS13610 ENOG4105FR1 rard protein HR071_RS13615 ENOG4108VUY thioesterase Superfamily protein HR071_RS13620 ENOG4105HDD phospholipase HR071_RS13625 ENOG4105C9U ATP-dependent DNA helicase RecQ HR071_RS13630 ENOG4105CCF Lysine exporter protein (Lyse ygga) HR071_RS13640 ENOG410829K Lysine exporter protein (Lyse ygga) HR071_RS13645 ENOG4108EUD Lysophospholipase HR071_RS13650 ENOG4105DQF Hydrolase HR071_RS13655 ENOG4105EMK carboxylate amino acid amine transporter HR071_RS13660 ENOG4105DZ2 Transcriptional regulator HR071_RS13680 ENOG4105CV1 Transketolase (EC 2.2.1.1) HR071_RS13685 ENOG4106KNT transcriptional regulator HR071_RS13690 ENOG4105F52 Transcriptional regulator HR071_RS13695 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HR071_RS13705 ENOG4105C5B carbamate kinase HR071_RS13710 ENOG4107REC cytoplasmic protein HR071_RS13715 ENOG4107R1Q Membrane protein FdrA HR071_RS13725 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) HR071_RS13730 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) HR071_RS13735 ENOG4108I5U Uridine phosphorylase HR071_RS13750 ENOG4105JN3 extra-cytoplasmic solute receptor family protein HR071_RS13755 ENOG4108RTU Aldolase HR071_RS13760 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 HR071_RS13765 ENOG4107HP6 Transcriptional regulator HR071_RS13770 ENOG4105CGY Dna recombination protein HR071_RS13780 ENOG4105JC1 sterol-binding domain protein HR071_RS13790 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) HR071_RS13795 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) HR071_RS13800 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) HR071_RS13810 ENOG4105MDZ Transcriptional activator rfaH HR071_RS13815 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) HR071_RS13820 ENOG4108EX3 reductase HR071_RS13840 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein HR071_RS13845 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) HR071_RS13850 ENOG4108RR8 protoporphyrinogen oxidase HR071_RS13875 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b HR071_RS13880 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) HR071_RS13885 ENOG4105PC1 Conserved Protein HR071_RS13890 ENOG4105E27 serine threonine protein kinase HR071_RS13895 ENOG4108Z33 Thiol disulfide Interchange Protein HR071_RS13905 ENOG4106HNH Acyl-transferase HR071_RS13910 ENOG4105C2M dna polymerase I HR071_RS13925 ENOG4105D4P Coproporphyrinogen iii oxidase HR071_RS13930 ENOG4106FIY HR071_RS13935 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HR071_RS13940 ENOG4105CUX Signal transduction histidine kinase HR071_RS13945 ENOG4105C5F glutamine synthetase HR071_RS13950 ENOG4105CI3 gtp-binding protein typa HR071_RS13955 ENOG4105E98 transcriptional regulator DeoR family HR071_RS13960 ENOG4108MGF sugar kinase HR071_RS13965 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HR071_RS13970 ENOG4105D2M Aldolase HR071_RS13975 ENOG4105CPQ Dehydrogenase HR071_RS13985 ENOG4105CSH Transporter HR071_RS13995 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 HR071_RS14010 ENOG4105SUU thioesterase domain HR071_RS14020 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system HR071_RS14050 ENOG41068KX affects formate dehydrogenase-N HR071_RS14060 ENOG4108MG3 formate dehydrogenase HR071_RS14065 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HR071_RS14125 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HR071_RS14135 ENOG4108RPX mosc domain containing protein HR071_RS14140 ENOG4105E0F Histidine kinase HR071_RS14145 ENOG4105E3W Two component transcriptional regulator (Winged helix family HR071_RS14150 ENOG4105FMW periplasmic HR071_RS14165 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HR071_RS14180 ENOG4105EBK exported protein HR071_RS14185 ENOG4108VTS Membrane HR071_RS14190 ENOG41065TG regulatoR HR071_RS14200 ENOG4105DP0 ferredoxin-NADP reductase HR071_RS14205 ENOG4105CBT Fructose-1,6-bisphosphatase HR071_RS14215 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HR071_RS14230 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase HR071_RS14245 ENOG41063M6 Cell Division Protein HR071_RS14250 ENOG4105ETE Transcriptional regulator (LacI family HR071_RS14255 ENOG4105C25 Primosomal protein n' HR071_RS14265 ENOG4107S01 Repressor protein MetJ HR071_RS14275 ENOG4105C28 cystathionine HR071_RS14280 ENOG4105CFH Aspartokinase HR071_RS14290 ENOG4105CGH 5'-nucleotidase HR071_RS14295 ENOG4105SYT Methylenetetrahydrofolate reductase HR071_RS14305 ENOG4108Q5Y Membrane HR071_RS14310 ENOG4108XC3 NADH ubiquinone oxidoreductase HR071_RS14315 ENOG4105DCT glycerol dehydrogenase HR071_RS14320 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HR071_RS14325 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HR071_RS14330 ENOG4105DM4 PTS System HR071_RS14335 ENOG4108YRF PTS System HR071_RS14345 ENOG4108AHH pyruvate formate lyase II activase HR071_RS14350 ENOG4108XCZ PTS System HR071_RS14355 ENOG4106R3P AraC family transcriptional regulator HR071_RS14360 ENOG4105DIJ Phosphoethanolamine transferase HR071_RS14375 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase HR071_RS14390 ENOG4105C5Q Transcriptional regulator HR071_RS14400 ENOG4105CH2 amidohydrolase HR071_RS14410 ENOG4105EJ2 Transcriptional regulator HR071_RS14415 ENOG4108Y73 Membrane HR071_RS14465 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase HR071_RS14500 ENOG4105PM1 preprotein translocase subunit SecE HR071_RS14505 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HR071_RS14540 ENOG4105D41 biosynthesis protein thiH HR071_RS14550 ENOG4105WHD thiamine biosynthesis protein ThiS HR071_RS14555 ENOG4105D06 uba thif-type nad fad binding protein HR071_RS14565 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) HR071_RS14590 ENOG4105R2J Conserved Protein HR071_RS14600 ENOG4108T8B Protein of unknown function (DUF1481) HR071_RS14605 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism HR071_RS14610 ENOG4105BZU Histidine kinase HR071_RS14615 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HR071_RS14620 ENOG4105C12 Phosphoribosylglycinamide synthetase HR071_RS14650 ENOG41062WK cellular response to acidity HR071_RS14655 ENOG4105K5X acetyltransferase HR071_RS14665 ENOG4107QP3 malate synthase g HR071_RS14670 ENOG4108I9X Isocitrate lyase HR071_RS14680 ENOG41069M3 Transcriptional regulator HR071_RS14685 ENOG4105C3R Methionine synthase HR071_RS14695 ENOG4105EAM Na Pi-cotransporter HR071_RS14705 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein HR071_RS14710 ENOG4105F3R pts system mannose fructose sorbose family iid HR071_RS14715 ENOG4105ETZ PTS System HR071_RS14720 ENOG4105KPI PTS system sorbose subfamily IIB component HR071_RS14725 ENOG4108XCU pts system HR071_RS14730 ENOG4105CHR reductase HR071_RS14735 ENOG4105DKT Transcriptional regulator HR071_RS14740 ENOG4105FE9 pseudouridine synthase HR071_RS14745 ENOG4108ZR5 Conserved Protein HR071_RS14750 ENOG4105CFH Aspartokinase HR071_RS14765 ENOG4108MDC (LipO)protein HR071_RS14770 ENOG4108Q9C Periplasmic Protein HR071_RS14775 ENOG4105E3R (LipO)protein HR071_RS14790 ENOG4105EG2 ABC transporter, permease HR071_RS14795 ENOG4105D56 permease protein HR071_RS14800 ENOG4107FKK extracellular solute-binding protein family 1 HR071_RS14805 ENOG4108IJ9 (ABC) transporter HR071_RS14815 ENOG4107W52 maltose operon periplasmic protein HR071_RS14835 ENOG41080IJ Diacylglycerol kinase HR071_RS14845 ENOG4107R73 Mate efflux family protein HR071_RS14850 ENOG4105VDW Csbd family HR071_RS14855 ENOG4105MYN Zinc uptake regulation protein HR071_RS14860 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HR071_RS14865 ENOG4105P4Z Phage shock protein G HR071_RS14870 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HR071_RS14875 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HR071_RS14880 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) HR071_RS14885 ENOG4106YT9 Enoyl-CoA hydratase HR071_RS14890 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) HR071_RS14895 ENOG4105ETE Transcriptional regulator (LacI family HR071_RS14900 ENOG4105CDU Replicative dna helicase HR071_RS14905 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HR071_RS14910 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HR071_RS14915 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HR071_RS14920 ENOG4105CGF Aromatic amino acid aminotransferase HR071_RS14925 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HR071_RS14930 ENOG4105C7S Dehydrogenase HR071_RS14935 ENOG4107QN2 dihydrolipoyl dehydrogenase HR071_RS14940 ENOG4105CMV Succinyl-CoA synthetase subunit beta HR071_RS14945 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HR071_RS14950 ENOG4107QPK )-transporter HR071_RS14955 ENOG4105DG4 malate L-lactate dehydrogenase HR071_RS14970 ENOG4105F0S class B acid phosphatase HR071_RS14975 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme HR071_RS14980 ENOG4105MSB protein, conserved in bacteria HR071_RS14985 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HR071_RS14990 ENOG4108UUM single-stranded DNA-binding protein HR071_RS14995 ENOG4105PMV Membrane HR071_RS15000 ENOG4108M8H domain protein HR071_RS15005 ENOG4108W3Q Transcriptional regulator HR071_RS15010 ENOG4108Z4X TRANSCRIPTIONal HR071_RS15015 ENOG4105C7N Xanthine uracil vitamin C permease HR071_RS15020 ENOG4105EEQ Na H antiporter HR071_RS15025 ENOG4105CMU LysR family (Transcriptional regulator HR071_RS15035 ENOG41067MG lrgb family HR071_RS15045 ENOG41062QD Membrane HR071_RS15050 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HR071_RS15060 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit HR071_RS15065 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein HR071_RS15070 ENOG4105DVI reductase, NrfD HR071_RS15075 ENOG4108QKW cytochrome c-type biogenesis protein HR071_RS15085 ENOG4108W0S formate-dependent nitrite reductase complex HR071_RS15090 ENOG4105CK2 sodium dicarboxylate symporter HR071_RS15095 ENOG41082ND Uncharacterized protein yjcO HR071_RS15100 ENOG4108JQ7 (ABC) transporter HR071_RS15105 ENOG4105C3U ABC transporter HR071_RS15110 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HR071_RS15115 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HR071_RS15130 ENOG4105ETP RND efflux system, outer membrane lipoprotein HR071_RS15135 ENOG4108MI0 Resistance protein HR071_RS15140 ENOG4105J12 Multidrug resistance protein mdtN HR071_RS15150 ENOG4105EUZ Beta-lactamase domain protein HR071_RS15155 ENOG4107TFG D-allose kinase HR071_RS15160 ENOG4105UP7 3-epimerase HR071_RS15165 ENOG4105CNN ABC, transporter HR071_RS15170 ENOG4105C2J ABC transporter HR071_RS15175 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HR071_RS15180 ENOG4105NYY transcriptional regulator, RpiR HR071_RS15185 ENOG4108YZG isomerase HR071_RS15195 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein HR071_RS15200 ENOG410849A acetyltransferase, (GNAT) family HR071_RS15210 ENOG4105FD8 phosphonate metabolism protein PhnM HR071_RS15215 ENOG4105HRV phosphonate c-p lyase system protein phnl HR071_RS15220 ENOG4105ENV phosphonate C-P lyase system protein PhnK HR071_RS15225 ENOG4105FT8 Phosphonate metabolism HR071_RS15230 ENOG4105EKV Phosphonate metabolism protein HR071_RS15235 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH HR071_RS15240 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG HR071_RS15245 ENOG4107RJJ Transcriptional regulator HR071_RS15255 ENOG4105EHI Phosphonate ABC transporter, periplasmic HR071_RS15265 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase HR071_RS15270 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HR071_RS15275 ENOG4108F5E vimentin HR071_RS15280 ENOG4108YIV HR071_RS15285 ENOG4105CSH Transporter HR071_RS15295 ENOG4105ECM Sensor protein basS pmrB HR071_RS15300 ENOG4105XJC Two component transcriptional regulator (Winged helix family HR071_RS15305 ENOG4105DIJ Phosphoethanolamine transferase HR071_RS15310 ENOG4105D5Q Arginine ornithine antiporter HR071_RS15315 ENOG4106ZGR Transcriptional regulator HR071_RS15320 ENOG4105CXN decarboxylase HR071_RS15325 ENOG4108K2B transcriptional regulator HR071_RS15330 ENOG4105F8D glycoside hydrolase family 4 HR071_RS15335 ENOG4108R5S membrane HR071_RS15340 ENOG4107GFK fumarate HR071_RS15345 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HR071_RS15350 ENOG4108MRH transcriptional regulatory protein HR071_RS15355 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HR071_RS15360 ENOG4105VR1 Pfam:DUF1271 HR071_RS15365 ENOG410830R acetyltransferase HR071_RS15370 ENOG4105CW0 outer membrane usher protein HR071_RS15375 ENOG4108VCD Chaperone HR071_RS15385 ENOG4108BMY protease HR071_RS15390 ENOG4108NKV transcriptional regulator HR071_RS15400 ENOG410830R acetyltransferase HR071_RS15415 ENOG4105CRK lysyL-tRNA synthetase HR071_RS15420 ENOG4105DUX Transporter HR071_RS15425 ENOG4105CXN decarboxylase HR071_RS15430 ENOG4105D5Q Arginine ornithine antiporter HR071_RS15435 ENOG4108M3R transcriptional activator CadC HR071_RS15460 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HR071_RS15470 ENOG4108YGG dna repair protein HR071_RS15475 ENOG4106549 Antirestriction protein HR071_RS15480 ENOG4106H6R UPF0380 protein HR071_RS15495 ENOG4108KZE transcriptional regulator HR071_RS15500 ENOG4105TS0 gtp-binding protein HR071_RS15550 ENOG4105KNY Microcompartments protein HR071_RS15560 ENOG4106R3P AraC family transcriptional regulator HR071_RS15565 ENOG4105C2F Histidine kinase HR071_RS15570 ENOG4105EKQ RNA-directed DNA polymerase HR071_RS15585 ENOG4105F1A Pyruvate formate-lyase HR071_RS15595 ENOG4107R7Y intracellular protease Pfpi family HR071_RS15605 ENOG4108EKI Dehydrogenase HR071_RS15610 ENOG4105EHR propanediol utilization protein pduB HR071_RS15635 ENOG4105D5K Hemolysin activator protein HR071_RS15690 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family HR071_RS15700 ENOG4105D5Q Arginine ornithine antiporter HR071_RS15705 ENOG4105CXN decarboxylase HR071_RS15710 ENOG4105D5Q Arginine ornithine antiporter HR071_RS15725 ENOG41067TZ transcriptional regulator, MarR family HR071_RS15750 ENOG4108SIC Transcriptional regulator HR071_RS15755 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HR071_RS15765 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter HR071_RS15770 ENOG4108IJ0 Aspartate ammonia-lyase HR071_RS15775 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 HR071_RS15780 ENOG4105DVH amino acid HR071_RS15795 ENOG4108ZVF (LipO)protein HR071_RS15800 ENOG4105MTB Uncharacterized protein YjeJ HR071_RS15805 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HR071_RS15815 ENOG4107PEH Entericidin EcnA/B family HR071_RS15820 ENOG4106BSU Entericidin B HR071_RS15825 ENOG4105KPY Small multidrug resistance protein HR071_RS15830 ENOG4105QNF Outer membrane lipoprotein HR071_RS15835 ENOG41066YJ Beta-lactamase HR071_RS15850 ENOG4105E33 succinate dehydrogenase HR071_RS15855 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HR071_RS15865 ENOG4107SC7 Inner membrane transporter yjeM HR071_RS15870 ENOG4106CG8 Inner membrane protein YjeO HR071_RS15875 ENOG4105EGS Mechanosensitive ion channel HR071_RS15915 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HR071_RS15920 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) HR071_RS15925 ENOG4105K8N protein family UPF0079, ATPase HR071_RS15930 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase HR071_RS15950 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HR071_RS15955 ENOG4107QJR hflk protein HR071_RS15960 ENOG4105EPW hflc protein HR071_RS15980 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HR071_RS15985 ENOG4105C2N RNA methyltransferase TrmH family group 3 HR071_RS15990 ENOG4107HP6 Transcriptional regulator HR071_RS15995 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HR071_RS16000 ENOG4105CSP Major Facilitator Superfamily HR071_RS16005 ENOG4105CTX dehydratase HR071_RS16015 ENOG4108P9J Phage shock protein A HR071_RS16020 ENOG4107VNS Protein of unknown function (DUF2491) HR071_RS16025 ENOG4105Z6B inner membrane protein yjfl HR071_RS16030 ENOG4108KXT Conserved Protein HR071_RS16035 ENOG4106032 Glutathionylspermidine synthase HR071_RS16040 ENOG4105CSU acyl-Coa dehydrogenase HR071_RS16045 ENOG4105S17 UPF0379 protein yjfN HR071_RS16050 ENOG4105WSB biofilm stress and motility protein A HR071_RS16055 ENOG4108MXZ Esterase HR071_RS16070 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC HR071_RS16075 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport HR071_RS16080 ENOG4106ETB IIa component HR071_RS16095 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HR071_RS16100 ENOG4105R3P Inner membrane protein yagU HR071_RS16105 ENOG4105KIT UPF0379 protein yjfY HR071_RS16120 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) HR071_RS16140 ENOG4108RS6 transposase HR071_RS16145 ENOG4105D7V transposase HR071_RS16155 ENOG4105FHY Opacity-associated protein A HR071_RS16160 ENOG4108V1T peptidylprolyl cis-trans isomerase HR071_RS16165 ENOG4105C85 amino acid HR071_RS16175 ENOG4105DXC membrane HR071_RS16180 ENOG4105ECR NmrA family HR071_RS16185 ENOG4105KVH Transcriptional regulator HR071_RS16190 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic HR071_RS16195 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HR071_RS16205 ENOG4108UUE Transcriptional regulator HR071_RS16210 ENOG41061GZ Protein of unknown function (DUF1107) HR071_RS16215 ENOG4105C37 (CBS) domain HR071_RS16225 ENOG4105CFU surface antigen HR071_RS16230 ENOG4105MA0 exported protein HR071_RS16235 ENOG4108ZHD aig2 family HR071_RS16240 ENOG4105F0N pyrophosphate phospho-hydrolase HR071_RS16245 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator HR071_RS16250 ENOG4105C2J ABC transporter HR071_RS16255 ENOG4107R9N ABC transporter HR071_RS16260 ENOG41062B0 ABC transporter, permease HR071_RS16270 ENOG4105DFU Cell wall formation (By similarity) HR071_RS16280 ENOG4105CMS peptidase U62, modulator of DNA gyrase HR071_RS16290 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) HR071_RS16295 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase HR071_RS16300 ENOG4105CG3 alpha amylase, catalytic region HR071_RS16305 ENOG4105C5Y PTS System HR071_RS16310 ENOG4105D4X repressor HR071_RS16320 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HR071_RS16325 ENOG4105KME endoribonuclease L-psp HR071_RS16340 ENOG4107C93 pyrBI operon leader peptide HR071_RS16345 ENOG4108UQ8 endoribonuclease L-psp HR071_RS16350 ENOG4105F6U Short-chain dehydrogenase reductase Sdr HR071_RS16355 ENOG4108XFH Transcriptional regulator HR071_RS16360 ENOG4105XEP YhcH YjgK YiaL family protein HR071_RS16375 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) HR071_RS16380 ENOG4108MJ3 acetyltransferase HR071_RS16385 ENOG4108M3P Membrane HR071_RS16390 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HR071_RS16395 ENOG4105MYG DNA polymerase iii, chi subunit HR071_RS16405 ENOG4108M8S permease YjgP YjgQ family protein HR071_RS16410 ENOG4108K5H permease YjgP YjgQ family protein HR071_RS16415 ENOG4105D7A ATP-binding protein HR071_RS16420 ENOG4105DQ4 alcohol dehydrogenase HR071_RS16520 ENOG4108WUH Transcriptional regulator, TetR family HR071_RS16530 ENOG4105C94 Transporter HR071_RS16540 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HR071_RS16545 ENOG4108MJ5 VirK protein HR071_RS16550 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) HR071_RS16555 ENOG4107BJW polysaccharide deacetylase HR071_RS16570 ENOG4105E0A ABC, transporter HR071_RS16575 ENOG4108IHU transport system permease protein HR071_RS16580 ENOG4105DQ5 transport system permease protein HR071_RS16585 ENOG4108HUF Transporter HR071_RS16590 ENOG4105GAV receptor HR071_RS16595 ENOG4108S3W Anti-feci sigma factor, fecr HR071_RS16600 ENOG4108SF5 RNA Polymerase HR071_RS16650 ENOG4108P8R HR071_RS16660 ENOG4105F4K antigen 43 HR071_RS16670 ENOG4106H6R UPF0380 protein HR071_RS16675 ENOG4105F5W AtP-binding protein HR071_RS16680 ENOG4105D70 Integrase catalytic subunit HR071_RS16695 ENOG4108YXQ IS66 Orf2 family protein HR071_RS16700 ENOG4105E5H Transposase HR071_RS16710 ENOG4108YGG dna repair protein HR071_RS16720 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles HR071_RS16730 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) HR071_RS16740 ENOG4107W7X Aldolase HR071_RS16750 ENOG4105DKT Transcriptional regulator HR071_RS16755 ENOG4105C6Z Gluconate HR071_RS16760 ENOG4105C01 Dihydroxy-acid dehydratase HR071_RS16765 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HR071_RS16770 ENOG4106P37 HTH-type transcriptional regulator YjhI HR071_RS16775 ENOG4108PQ7 sgc region transcriptional regulator HR071_RS16780 ENOG4108RK0 3-epimerase HR071_RS16785 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HR071_RS16790 ENOG4106P19 photosystem i assembly btpa HR071_RS16795 ENOG4105DT3 PTS system, galactitol-specific IIc component HR071_RS16800 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) HR071_RS16805 ENOG4105CN9 Peptidase m42 family protein HR071_RS16815 ENOG4105DTA methyltransferase HR071_RS16820 ENOG41080VW acetyltransferase HR071_RS16825 ENOG4105YCT UPF0386 protein HR071_RS16850 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) HR071_RS16855 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria HR071_RS16860 ENOG4108W9T type 1 fimbriae regulatory protein HR071_RS16865 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off HR071_RS16870 ENOG4108RQP Major type 1 subunit fimbrin HR071_RS16875 ENOG4108SER Transposase HR071_RS16880 ENOG4108S54 Fimbrial protein HR071_RS16885 ENOG4108NAE Fimbrial chaperone protein HR071_RS16890 ENOG4105CW0 outer membrane usher protein HR071_RS16895 ENOG4108SQA Fimbrial HR071_RS16900 ENOG4108T65 Fimbrial HR071_RS16905 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin HR071_RS16910 ENOG4107EFN gluconate transport system permease 3 HR071_RS16920 ENOG4105DEI Mannitol dehydrogenase HR071_RS16925 ENOG4105C6F GntR Family Transcriptional Regulator HR071_RS16945 ENOG4107YNJ LysR family Transcriptional regulator HR071_RS16950 ENOG4105DYB Isoaspartyl dipeptidase HR071_RS16955 ENOG4108P2H Inner membrane protein YjiG HR071_RS16960 ENOG41074DU domain protein HR071_RS16970 ENOG4105CBP Major Facilitator HR071_RS16975 ENOG4108ZK4 sdia-regulated domain-containing protein HR071_RS16985 ENOG4105CIZ coA-substrate-specific enzyme activase HR071_RS16990 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase HR071_RS16995 ENOG4106BRA Membrane HR071_RS17005 ENOG4106DIZ Domain of unknown function (DUF1127) HR071_RS17015 ENOG4105FU6 Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease La (By similarity) HR071_RS17020 ENOG4107QTH restriction modification system DNA specificity domain HR071_RS17030 ENOG4108F3G Type I restriction-modification system, R subunit HR071_RS17045 ENOG4105CKI cobalamin synthesis protein HR071_RS17050 ENOG4105VCD cytoplasmic protein HR071_RS17055 ENOG4105D22 carbon starvation protein HR071_RS17060 ENOG4105C8Q Methyl-accepting chemotaxis HR071_RS17065 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HR071_RS17075 ENOG4108ERU trap dicarboxylate transporter subunit DctP HR071_RS17080 ENOG4105EEQ Na H antiporter HR071_RS17085 ENOG410617M Transcriptional regulator HR071_RS17090 ENOG4105CPQ Dehydrogenase HR071_RS17100 ENOG4105RI1 glycoprotein receptor HR071_RS17105 ENOG4106CVF DNA replication protein HR071_RS17120 ENOG4105DWK Membrane HR071_RS17125 ENOG4108N8T regulatoR HR071_RS17130 ENOG4108T94 DNA-binding transcriptional activator BglJ HR071_RS17135 ENOG4108819 ferric iron reductase HR071_RS17140 ENOG4105YBH Protein of unknown function (DUF1435) HR071_RS17160 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) HR071_RS17165 ENOG4108WPU DNA polymerase III subunit psi HR071_RS17170 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HR071_RS17175 ENOG4105PAD Hydrolase HR071_RS17185 ENOG4105K3G Periplasmic Protein HR071_RS17195 ENOG4108NRW Phospholipase, patatin family HR071_RS17200 ENOG4105EYA deoxyribonuclease HR071_RS17205 ENOG41076CZ activating enzyme HR071_RS17210 ENOG4105G0K glycine radical enzyme YjjI family HR071_RS17230 ENOG4105D3A purine nucleoside phosphorylase DeoD-type HR071_RS17235 ENOG4105EUP HipA domain protein HR071_RS17245 ENOG41062Z9 Membrane HR071_RS17250 ENOG4105EAC phosphoserine phosphatase HR071_RS17255 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HR071_RS17260 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase HR071_RS17265 ENOG4105C5H ABC transporter HR071_RS17270 ENOG4107SC1 transglycosylase HR071_RS17290 ENOG4105UEI Transcriptional Regulator AraC Family HR071_RS17295 ENOG4108RH0 Crea protein HR071_RS17300 ENOG4105E3W Two component transcriptional regulator (Winged helix family HR071_RS17305 ENOG4105EB3 Histidine kinase HR071_RS17310 ENOG4105CT7 inner membrane cred family protein HR071_RS17315 ENOG41065U4 response regulator HR071_RS17320 ENOG410759A HR071_RS17325 ENOG4106FVC RNA methyltransferase HR071_RS17335 ENOG4105CFH Aspartokinase HR071_RS17345 ENOG4105D98 threonine synthase HR071_RS17350 ENOG41062C6 Protein of unknown function (DUF2502) HR071_RS17360 ENOG4105BZG amino acid carrier protein HR071_RS17370 ENOG4108RIR Molybdenum cofactor biosynthesis protein HR071_RS17375 ENOG4106HK8 GPR1 FUN34 yaaH family protein HR071_RS17380 ENOG4108QUJ UPF0174 protein YaaW HR071_RS17385 ENOG4108WTA UPF0412 protein YaaI HR071_RS17400 ENOG4108SER Transposase HR071_RS17405 ENOG4105WI6 cell killing protein encoded within cryptic prophage HR071_RS17415 ENOG41061MV Arylsulfatase HR071_RS17425 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) HR071_RS17430 ENOG41063Z6 transcriptional regulator, lysR family HR071_RS17450 ENOG410647N response to DNA damage stimulus HR071_RS17455 ENOG4105DTN riboflavin biosynthesis protein ribF HR071_RS17470 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HR071_RS17495 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HR071_RS17500 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HR071_RS17540 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HR071_RS17545 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein HR071_RS17550 ENOG4105C54 Major Facilitator superfamily HR071_RS17565 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) HR071_RS17595 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HR071_RS17600 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HR071_RS17605 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HR071_RS17610 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) HR071_RS17615 ENOG4105D3G Pseudouridine synthase HR071_RS17625 ENOG4105CQ2 DNA polymerase HR071_RS17630 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase HR071_RS17645 ENOG41063TF transcriptional regulator (AraC HR071_RS17650 ENOG4108RVA ribokinase HR071_RS17655 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HR071_RS17675 ENOG4108KF1 Membrane HR071_RS17685 ENOG4106SMU thiamine transporter membrane protein HR071_RS17690 ENOG4105DP9 ABC transporter HR071_RS17730 ENOG41064T2 transcriptional regulator, lysR family HR071_RS17740 ENOG4105C7K acetolactate synthase HR071_RS17745 ENOG4108ZP8 Acetolactate synthase small subunit HR071_RS17755 ENOG4107B7Y DNA-binding transcriptional regulator FruR HR071_RS17770 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HR071_RS17775 ENOG4105CJN penicillin-binding protein HR071_RS17780 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HR071_RS17785 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HR071_RS17795 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) HR071_RS17800 ENOG4105CNI cell division protein FtsW HR071_RS17815 ENOG4105CPF Cell wall formation (By similarity) HR071_RS17820 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HR071_RS17825 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HR071_RS17830 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HR071_RS17850 ENOG4105M6F mutator MutT protein HR071_RS17865 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HR071_RS17880 ENOG4105D7Q type ii secretion system HR071_RS17890 ENOG4108ZUW Major pilin subunit HR071_RS17895 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HR071_RS17900 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HR071_RS17905 ENOG4106A72 regulatory protein AmpE HR071_RS17910 ENOG4105C85 amino acid HR071_RS17915 ENOG4105GMB type VI secretion system effector, hcp1 family HR071_RS17920 ENOG41060S4 immunity protein HR071_RS17930 ENOG41060S4 immunity protein HR071_RS17975 ENOG4105I1F Resistance protein HR071_RS17985 ENOG4108BUD transposase HR071_RS18040 ENOG41073TP transcriptional regulator HR071_RS18045 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HR071_RS18050 ENOG4107QSN dihydrolipoamide acetyltransferase HR071_RS18055 ENOG4107QN2 dihydrolipoyl dehydrogenase HR071_RS18060 ENOG4108NST exported protein HR071_RS18060 ENOG4108NST exported protein HR071_RS18065 ENOG4107QIJ Aconitate hydratase 2 HR071_RS18085 ENOG4108ZRK uncharacterized protein yacC HR071_RS18090 ENOG4105E3B Multicopper oxidase HR071_RS18095 ENOG4105DZG Dehydrogenase HR071_RS18100 ENOG4108UGV hypoxanthine phosphoribosyltransferase HR071_RS18105 ENOG41077A9 carbonic anhydrase HR071_RS18110 ENOG4105DA5 (ABC) transporter HR071_RS18115 ENOG4105E3A (ABC) transporter HR071_RS18120 ENOG4108YTN IIa component HR071_RS18125 ENOG4107BJW polysaccharide deacetylase HR071_RS18135 ENOG4108A32 Transposase HR071_RS18140 ENOG4108A32 Transposase HR071_RS18145 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) HR071_RS18155 ENOG4105P0Q fimbrial-like protein YadC HR071_RS18160 ENOG4105SN2 fimbrial-like adhesin protein HR071_RS18165 ENOG4105SYG Fimbrial protein HR071_RS18170 ENOG4108XEY fimbrial-like adhesin protein HR071_RS18175 ENOG4105CW0 outer membrane usher protein HR071_RS18180 ENOG4108VEV chaperone HR071_RS18190 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HR071_RS18195 ENOG4105DJ0 Poly(A) Polymerase HR071_RS18200 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HR071_RS18215 ENOG4107XID 2'-5' rna ligase HR071_RS18220 ENOG4105CQ7 ATP-dependent helicase HR071_RS18225 ENOG4105BZ4 penicillin-binding protein HR071_RS18235 ENOG4108NAE Fimbrial chaperone protein HR071_RS18240 ENOG4105CW0 outer membrane usher protein HR071_RS18250 ENOG4105E0K tonB-dependent siderophore receptor HR071_RS18255 ENOG4105E0A ABC, transporter HR071_RS18260 ENOG4105J76 Periplasmic binding protein HR071_RS18265 ENOG4105S6R Iron-hydroxamate transporter permease subunit HR071_RS18290 ENOG4105EN6 Membrane HR071_RS18295 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) HR071_RS18310 ENOG4105C0H protease HR071_RS18315 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR HR071_RS18330 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) HR071_RS18335 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HR071_RS18360 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) HR071_RS18365 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HR071_RS18370 ENOG4105KNE Phosphatidate cytidylyltransferase HR071_RS18375 ENOG4105DZP Membrane-associated zinc metalloprotease HR071_RS18385 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) HR071_RS18390 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HR071_RS18415 ENOG4105C0B DNA polymerase III (alpha subunit) HR071_RS18425 ENOG4105CXN decarboxylase HR071_RS18430 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase HR071_RS18435 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HR071_RS18440 ENOG4105M1T rho-binding antiterminator HR071_RS18450 ENOG4108VWS Yaeq family HR071_RS18455 ENOG4108YZN class I peptide chain release factor HR071_RS18460 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion HR071_RS18465 ENOG4108UY0 (LipO)protein HR071_RS18475 ENOG4108R96 Methyltransferase, YaeB family HR071_RS18480 ENOG4108R8X outer membrane lipoprotein HR071_RS18485 ENOG4105D01 (LipO)protein HR071_RS18490 ENOG4108UMI ABC transporter, permease HR071_RS18495 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HR071_RS18500 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase HR071_RS18535 ENOG4105CV8 reductase HR071_RS18540 ENOG4105HEI LysR family (Transcriptional regulator HR071_RS18550 ENOG4105F2W methyltransferase HR071_RS18555 ENOG4105E9H Lytic Murein transglycosylase HR071_RS18565 ENOG4105D1A Methyltransferase HR071_RS18575 ENOG4107RZZ dna polymerase iii epsilon subunit HR071_RS18585 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase HR071_RS18590 ENOG4108WN0 inhibitor of vertebrate lysozyme HR071_RS18595 ENOG4107QPN acyl-Coa dehydrogenase HR071_RS18605 ENOG4105E7A Glutamine amidotransferase HR071_RS18610 ENOG4105F7V ErfK ybiS ycfS ynhG family protein HR071_RS18615 ENOG4108YS0 lipoprotein YafL HR071_RS18620 ENOG4108UK5 Transposase HR071_RS18635 ENOG4105D19 Role in flagellar biosynthesis (By similarity) HR071_RS18640 ENOG4105VS8 Flagellar biosynthetic protein fliq HR071_RS18645 ENOG4105CN7 Flagellar biosynthetic protein FliP HR071_RS18650 ENOG4105DD5 Flagellar motor switch protein HR071_RS18665 ENOG41090RK glycosyl transferase HR071_RS18690 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HR071_RS18695 ENOG4108ZC9 flagellar basal-body rod protein flgc HR071_RS18705 ENOG4105BZE flagellar hook protein, FlgE HR071_RS18710 ENOG4108KPB Flagellar basal-body rod protein FlgF HR071_RS18715 ENOG4105CGA flagellar basal-body rod protein FlgG HR071_RS18730 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HR071_RS18740 ENOG4105DTJ flagellar hook-associated protein HR071_RS18755 ENOG4105I03 Flagellin HR071_RS18760 ENOG410804A Flagellar hook-associated 2 domain-containing protein HR071_RS18790 ENOG4107RD7 Flagellar Motor Protein, MotA HR071_RS18800 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HR071_RS18805 ENOG4108HYG acetyltransferase HR071_RS18815 ENOG4108S2Y peptide Chain Release factor HR071_RS18820 ENOG4105CIN aminoacyl-histidine dipeptidase HR071_RS18840 ENOG4105FCK Membrane HR071_RS18870 ENOG4105EKX Restriction modification system DNA (Specificity HR071_RS18910 ENOG4105R3P Inner membrane protein yagU HR071_RS18920 ENOG4105PI0 Ferredoxin HR071_RS18930 ENOG4106PYX Receptor HR071_RS18975 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HR071_RS18980 ENOG4105ENX hydrolase HR071_RS18985 ENOG410642W LysR family Transcriptional regulator HR071_RS18990 ENOG4105EQ2 LysR family Transcriptional regulator HR071_RS18995 ENOG4107SET aldo keto reductase HR071_RS19005 ENOG4105TNG K13735 adhesin invasin HR071_RS19015 ENOG4105CV8 reductase HR071_RS19020 ENOG4108KBJ Inner membrane protein YkgB HR071_RS19025 ENOG41066GK UPF0379 protein ykgI HR071_RS19030 ENOG4107QN2 dihydrolipoyl dehydrogenase HR071_RS19035 ENOG4108K01 transcriptional regulator HR071_RS19040 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) HR071_RS19045 ENOG4107QR9 Iron-sulfur cluster binding protein HR071_RS19050 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) HR071_RS19075 ENOG4105BZU Histidine kinase HR071_RS19080 ENOG4108W9T type 1 fimbriae regulatory protein HR071_RS19090 ENOG4105C26 Dehydrogenase HR071_RS19100 ENOG4105C94 Transporter HR071_RS19105 ENOG4105BZU Histidine kinase HR071_RS19110 ENOG4108NUU Transcriptional regulator HR071_RS19115 ENOG4105SZ2 membrAne HR071_RS19120 ENOG4107SNB ankyrin repeat protein YahD HR071_RS19125 ENOG4105N16 Protein of unknown function (DUF2877) HR071_RS19130 ENOG4107R1Q Membrane protein FdrA HR071_RS19135 ENOG4107REC cytoplasmic protein HR071_RS19140 ENOG4105C5B carbamate kinase HR071_RS19145 ENOG4105DZC cytosine deaminase HR071_RS19150 ENOG4105DQ4 alcohol dehydrogenase HR071_RS19160 ENOG4105E82 cytochrome subunit of dehydrogenase HR071_RS19165 ENOG4105TDT uncharacterized protein yahO HR071_RS19170 ENOG4108JU7 Transcriptional regulator HR071_RS19175 ENOG4105CR4 methylisocitrate lyase HR071_RS19180 ENOG4105BZN citrate synthase HR071_RS19185 ENOG4105DXD 2-methylcitrate dehydratase HR071_RS19190 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HR071_RS19195 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin HR071_RS19200 ENOG4105DZC cytosine deaminase HR071_RS19205 ENOG4108UW5 maltose o-acetyltransferase HR071_RS19215 ENOG4105CNT hydrolase family 2 HR071_RS19220 ENOG4105ETE Transcriptional regulator (LacI family HR071_RS19225 ENOG4108K2P TRANSCRIPTIONal HR071_RS19255 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) HR071_RS19260 ENOG4108SC4 )-transporter HR071_RS19265 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HR071_RS19285 ENOG4106FTQ Taurine ABC transporter, periplasmic HR071_RS19290 ENOG4108IY8 ABC, transporter HR071_RS19295 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HR071_RS19300 ENOG4105E2B Taurine dioxygenase HR071_RS19305 ENOG4105D52 delta-aminolevulinic acid dehydratase HR071_RS19315 ENOG4108PNB DNA-binding transcriptional regulator HR071_RS19320 ENOG4107R6D beta-lactam binding protein AmpH HR071_RS19325 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 HR071_RS19330 ENOG4107QS8 (LipO)protein HR071_RS19335 ENOG4105FR5 inner membrane protein YaiY HR071_RS19340 ENOG4105UNH Membrane HR071_RS19345 ENOG4105CPF Cell wall formation (By similarity) HR071_RS19360 ENOG4105G6Z alkaline phosphatase HR071_RS19365 ENOG4105VIF phosphate starvation-inducible protein HR071_RS19370 ENOG4105BZU Histidine kinase HR071_RS19375 ENOG4105II7 pyrroline-5-carboxylate reductase HR071_RS19390 ENOG4105SS3 HR071_RS19395 ENOG4105HBA AroM protein HR071_RS19420 ENOG4105DKQ ROK family HR071_RS19425 ENOG4105F27 Major Facilitator HR071_RS19430 ENOG4105EYH Exonuclease HR071_RS19435 ENOG4107RH8 nuclease SbcCD subunit D HR071_RS19440 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HR071_RS19445 ENOG4105BZU Histidine kinase HR071_RS19450 ENOG4105CWM branched-chain amino acid transport system II carrier protein HR071_RS19455 ENOG4105C85 amino acid HR071_RS19460 ENOG4107R28 alpha amylase, catalytic region HR071_RS19470 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) HR071_RS19480 ENOG4105VIE preprotein translocase, subunit YajC HR071_RS19485 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HR071_RS19490 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HR071_RS19495 ENOG4105N1F Hnh endonuclease HR071_RS19500 ENOG4105DRB nucleoside-specific channel-forming protein HR071_RS19505 ENOG4108KIC (LipO)protein HR071_RS19515 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HR071_RS19520 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) HR071_RS19530 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HR071_RS19535 ENOG4108ZAI phosphatidylglycerophosphatase a HR071_RS19540 ENOG4105CPC Aldo Keto reductase HR071_RS19550 ENOG4105CTB Polyprenyl synthetase HR071_RS19565 ENOG4107S0N DJ-1 family HR071_RS19570 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) HR071_RS19580 ENOG4107RDB Major Facilitator HR071_RS19590 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HR071_RS19595 ENOG4105CCU oxidase (Subunit III) HR071_RS19600 ENOG4105BZ9 Cytochrome C oxidase, subunit I HR071_RS19605 ENOG4105E2S oxidase) subunit II HR071_RS19610 ENOG4105EYM Major Facilitator superfamily HR071_RS19615 ENOG4105IEY (LipO)protein HR071_RS19620 ENOG4105M85 Bola protein HR071_RS19625 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation HR071_RS19635 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) HR071_RS19640 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) HR071_RS19645 ENOG4105K70 DNA-binding protein HR071_RS19650 ENOG4105EIN peptidylprolyl cis-trans isomerase HR071_RS19655 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HR071_RS19660 ENOG4108TGP Thioesterase superfamily protein HR071_RS19670 ENOG4108NFA extracellular solute-binding protein HR071_RS19680 ENOG4108XM1 transcriptional regulator AsnC family HR071_RS19685 ENOG4105BZ1 (ABC) transporter HR071_RS19690 ENOG4105BZ1 (ABC) transporter HR071_RS19695 ENOG4108YZA Nitrogen regulatory protein pii HR071_RS19700 ENOG4105BZU Histidine kinase HR071_RS19705 ENOG4105C29 acyl-CoA thioesterase HR071_RS19710 ENOG4108MNP Glycoprotein polysaccharide metabolism HR071_RS19715 ENOG41080UX Methyltransferase HR071_RS19725 ENOG4105KCV RNA signal recognition particle 4.5S RNA HR071_RS19730 ENOG41066DG (EAL) domain protein HR071_RS19735 ENOG4105GSJ Inner membrane protein ylaC HR071_RS19740 ENOG4108UW5 maltose o-acetyltransferase HR071_RS19745 ENOG4105KF5 hemolysin expression-modulating protein HR071_RS19750 ENOG4108UKR Biofilm formation regulator YbaJ HR071_RS19755 ENOG4105BZS acriflavin resistance protein HR071_RS19760 ENOG4105C1P efflux transporter, rnd family, mfp subunit HR071_RS19765 ENOG4107XI7 Tetr family transcriptional regulator HR071_RS19770 ENOG4105EGS Mechanosensitive ion channel HR071_RS19775 ENOG4106428 Protein of unknown function (DUF2496) HR071_RS19780 ENOG4108URS primosomal replication protein n'' HR071_RS19785 ENOG4105WD1 Membrane HR071_RS19795 ENOG4107QMP dna polymerase iii subunits gamma and tau HR071_RS19830 ENOG4107RE1 Inosine-guanosine kinase HR071_RS19835 ENOG4105CKD glutathione-regulated potassium-efflux system protein HR071_RS19840 ENOG4105EU0 Major facilitator Superfamily HR071_RS19845 ENOG4105CGH 5'-nucleotidase HR071_RS19860 ENOG4108Z66 YbaK ebsC protein HR071_RS19865 ENOG4105MBR gumn family HR071_RS19870 ENOG41080ET plasmid maintenance system killer protein HR071_RS19875 ENOG41081XE plasmid maintenance system antidote protein, xre family HR071_RS19880 ENOG4105C59 p-type ATPase HR071_RS19885 ENOG4105CSV Glutaminase HR071_RS19890 ENOG4107RY6 amino acid HR071_RS19895 ENOG4108Z6Z Transcriptional regulator HR071_RS19905 ENOG4105G5H Membrane HR071_RS19910 ENOG4107QX8 SPFH domain, Band 7 family protein HR071_RS19915 ENOG41083J0 (ABC) transporter HR071_RS19920 ENOG4105C4B ABC transporter, permease HR071_RS19925 ENOG4107QR8 Thioredoxin HR071_RS19930 ENOG4105E1F short-chain dehydrogenase reductase HR071_RS19935 ENOG4108UJV acyl-CoA thioesterase i HR071_RS19940 ENOG4108I0Y (ABC) transporter HR071_RS19945 ENOG4105CV6 ABC transporter, permease HR071_RS19950 ENOG4105GMB type VI secretion system effector, hcp1 family HR071_RS19975 ENOG4107653 Transcriptional regulator HR071_RS19990 ENOG41060W2 glyoxylate carboligase HR071_RS19995 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HR071_RS20000 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HR071_RS20005 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HR071_RS20015 ENOG4105DTE Xanthine uracil vitamin C permease HR071_RS20020 ENOG4105BZW Glycerate kinase HR071_RS20025 ENOG4105S0E allantoin catabolism protein HR071_RS20030 ENOG4105CE7 Amidase, hydantoinase carbamoylase family HR071_RS20035 ENOG4105DG4 malate L-lactate dehydrogenase HR071_RS20040 ENOG4107R1Q Membrane protein FdrA HR071_RS20045 ENOG4107REC cytoplasmic protein HR071_RS20050 ENOG4105G5A Protein of unknown function (DUF2877) HR071_RS20055 ENOG4105C5B carbamate kinase HR071_RS20060 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HR071_RS20065 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HR071_RS20080 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HR071_RS20090 ENOG4105S2T inner membrane protein YbcI HR071_RS20095 ENOG4105WQ3 Rna-binding protein HR071_RS20115 ENOG4105UZW Tail fiber assembly protein HR071_RS20120 ENOG4108WF3 methyltransferase HR071_RS20125 ENOG4108NC2 Outer membrane protease HR071_RS20130 ENOG4105QUW HR071_RS20135 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit HR071_RS20140 ENOG410802X bacteriophage n4 adsorption protein b HR071_RS20145 ENOG4105GR3 Histidine kinase HR071_RS20150 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HR071_RS20155 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HR071_RS20160 ENOG410624V efflux system protein HR071_RS20165 ENOG4105EP1 Efflux transporter rnd family, mfp subunit HR071_RS20170 ENOG4108IJF Heavy metal efflux pump, CzcA HR071_RS20175 ENOG4105C85 amino acid HR071_RS20180 ENOG4105CUY Mechanosensitive ion channel HR071_RS20185 ENOG4108RCM Nitroreductase HR071_RS20190 ENOG4105MSB protein, conserved in bacteria HR071_RS20195 ENOG4105WQ6 Membrane HR071_RS20205 ENOG4107635 Hok Gef family protein HR071_RS20210 ENOG4108SER Transposase HR071_RS20220 ENOG4108SER Transposase HR071_RS20235 ENOG4105CNN ABC, transporter HR071_RS20240 ENOG4105C2J ABC transporter HR071_RS20250 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator HR071_RS20255 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) HR071_RS20260 ENOG4105DKT Transcriptional regulator HR071_RS20265 ENOG4108HHA Transketolase HR071_RS20270 ENOG4108IUS Transketolase HR071_RS20275 ENOG4108TSE Transferase HR071_RS20280 ENOG4107RNH Outer membrane receptor FepA HR071_RS20285 ENOG4105E93 esterase HR071_RS20290 ENOG41085A6 mbth domain-containing protein HR071_RS20295 ENOG4105C0W non-ribosomal peptide synthetase HR071_RS20300 ENOG4108QY5 Ferric enterobactin transport protein HR071_RS20305 ENOG4105E0A ABC, transporter HR071_RS20310 ENOG4105TVJ transport system, permease HR071_RS20315 ENOG4105DQ5 transport system permease protein HR071_RS20325 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein HR071_RS20330 ENOG4105E4F Isochorismate synthase HR071_RS20335 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HR071_RS20340 ENOG4105WQI isochorismatase HR071_RS20345 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HR071_RS20350 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) HR071_RS20355 ENOG4105D22 carbon starvation protein HR071_RS20360 ENOG4105VCD cytoplasmic protein HR071_RS20365 ENOG4107SCQ Iron-containing alcohol dehydrogenase HR071_RS20370 ENOG4105CHM Aminotransferase HR071_RS20375 ENOG4105GTN ParB Domain Protein Nuclease HR071_RS20380 ENOG4105BZV Phosphoadenosine phosphosulfate reductase HR071_RS20385 ENOG4105DQS Transcriptional regulator HR071_RS20390 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase HR071_RS20395 ENOG4105D3R alkyl hydroperoxide reductase HR071_RS20400 ENOG4108JU3 Alkyl hydroperoxide reductase HR071_RS20405 ENOG4108U51 Universal stress protein HR071_RS20410 ENOG4105NXH GreA GreB family elongation factor HR071_RS20415 ENOG4105KTS ribonuclease HR071_RS20420 ENOG4107QPK )-transporter HR071_RS20435 ENOG4105CHY citrate lyase, alpha HR071_RS20440 ENOG4105CI0 Citrate lyase HR071_RS20450 ENOG4105DUA (citrate (pro-3S)-lyase ligase HR071_RS20455 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism HR071_RS20460 ENOG4106YYS transcriptional regulatory protein HR071_RS20465 ENOG4105CEE C4-dicarboxylate transporter HR071_RS20470 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) HR071_RS20490 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) HR071_RS20515 ENOG4105DZ1 carboxypeptidase HR071_RS20520 ENOG4105K6T rare lipoprotein A HR071_RS20525 ENOG4105CNI cell division protein FtsW HR071_RS20530 ENOG4105CJN penicillin-binding protein HR071_RS20540 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) HR071_RS20545 ENOG4108TGR phosphatase HR071_RS20555 ENOG4105DJF DNA polymerase III, delta' subunit HR071_RS20570 ENOG4107PAI alpha helical protein HR071_RS20580 ENOG4107JFD Sel1 repeat HR071_RS20585 ENOG41069CF Protein of unknown function (DUF1266) HR071_RS20590 ENOG4105QFC Hsc56 co-chaperone of HscC HR071_RS20595 ENOG4105F7F Chaperone HR071_RS20605 ENOG4105CDA abc transporter atp-binding protein HR071_RS20610 ENOG4105DRP amino acid AbC transporter HR071_RS20615 ENOG4105EAD ABC transporter HR071_RS20620 ENOG4107RP9 extracellular solute-binding protein, family 3 HR071_RS20625 ENOG4107U91 Rhomboid family HR071_RS20630 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HR071_RS20635 ENOG4108JU5 Magnesium and cobalt efflux protein HR071_RS20645 ENOG4105C9A Phoh family HR071_RS20655 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HR071_RS20700 ENOG4105CAQ asparagine synthetase HR071_RS20705 ENOG4105D4U had-superfamily hydrolase, subfamily iia HR071_RS20710 ENOG4105E2R ROK family HR071_RS20715 ENOG4105CE4 GlcNAc 6-P deacetylase HR071_RS20725 ENOG4105CI1 PTS System HR071_RS20745 ENOG4105EE5 Membrane protein terC HR071_RS20750 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HR071_RS20755 ENOG4105C0A alcohol dehydrogenase HR071_RS20760 ENOG4107S2N Type III effector Hrp-dependent HR071_RS20765 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HR071_RS20770 ENOG4105MVE transcriptional regulator HR071_RS20785 ENOG4105GX6 (LipO)protein HR071_RS20790 ENOG41090R7 Ferric uptake HR071_RS20800 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) HR071_RS20805 ENOG4105NNH LexA regulated protein HR071_RS20810 ENOG4105EV9 Alpha Beta Hydrolase HR071_RS20815 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) HR071_RS20820 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 HR071_RS20825 ENOG4105D5Q Arginine ornithine antiporter HR071_RS20830 ENOG4105CXN decarboxylase HR071_RS20840 ENOG4105EEX Two component transcriptional regulator (Winged helix family HR071_RS20845 ENOG4105C08 Histidine kinase HR071_RS20870 ENOG4105XIQ Protein of unknown function (DUF2517) HR071_RS20875 ENOG4107SEY Conserved Protein HR071_RS20880 ENOG4105CVP deoxyribo-dipyrimidine photolyase HR071_RS20885 ENOG4105DUX Transporter HR071_RS20890 ENOG4107QNR UPF0135 protein HR071_RS20895 ENOG4105P4J Allophanate hydrolase, subunit 1 HR071_RS20900 ENOG4107R7A Allophanate hydrolase subunit 2 HR071_RS20905 ENOG4105E7W lamb ycsf family protein HR071_RS20910 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) HR071_RS20915 ENOG4108KK1 membrane protein AbrB duplication HR071_RS20920 ENOG41073TP transcriptional regulator HR071_RS20925 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HR071_RS20930 ENOG4105CPQ Dehydrogenase HR071_RS20935 ENOG4105CHR reductase HR071_RS20945 ENOG4105CTX dehydratase HR071_RS20950 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit HR071_RS20960 ENOG4105CG6 trap dicarboxylate transporter dctm subunit HR071_RS20965 ENOG4105BZN citrate synthase HR071_RS20975 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HR071_RS20980 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HR071_RS20985 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) HR071_RS20990 ENOG4105E33 succinate dehydrogenase HR071_RS20995 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HR071_RS21000 ENOG4105C7S Dehydrogenase HR071_RS21010 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HR071_RS21015 ENOG4105FDP GntR family transcriptional regulator HR071_RS21020 ENOG4105DM4 PTS System HR071_RS21025 ENOG4105C8I hydrolase, family 38 HR071_RS21035 ENOG4105C4M (Ubiquinol oxidase) subunit I HR071_RS21040 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HR071_RS21050 ENOG4105KJB cyd operon protein YbgE HR071_RS21055 ENOG4107YD3 Thioesterase HR071_RS21060 ENOG4105E02 MotA TolQ exbB proton channel HR071_RS21070 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA HR071_RS21080 ENOG4105KCK Peptidoglycan-associated lipoprotein HR071_RS21085 ENOG4105UFD tol-pal system protein YbgF HR071_RS21125 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) HR071_RS21130 ENOG4106Z1T Nicotinamide Mononucleotide Transporter HR071_RS21135 ENOG4105PGM cation diffusion facilitator family transporter HR071_RS21140 ENOG4105JND homeobox protein HR071_RS21145 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HR071_RS21155 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HR071_RS21165 ENOG4105F0Z galactose-1-phosphate uridylyltransferase HR071_RS21170 ENOG4105CMR udp-glucose 4-epimerase HR071_RS21175 ENOG4105DKW ABC transporter HR071_RS21180 ENOG4105F4R Transcriptional regulator mode HR071_RS21190 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HR071_RS21195 ENOG4105E0C molybdate abc transporter HR071_RS21200 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) HR071_RS21205 ENOG4108K4B hydrolase HR071_RS21215 ENOG4105F04 LysR family Transcriptional regulator HR071_RS21220 ENOG4105C7F AcnD-accessory protein PrpF HR071_RS21225 ENOG4107QPK )-transporter HR071_RS21230 ENOG4107QM5 aconitate hydratase HR071_RS21235 ENOG4105NBR Pectinesterase HR071_RS21240 ENOG4108V1U phospholipid-binding protein HR071_RS21245 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HR071_RS21260 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HR071_RS21265 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) HR071_RS21275 ENOG4105CHW UPF0052 protein HR071_RS21285 ENOG4108RIR Molybdenum cofactor biosynthesis protein HR071_RS21295 ENOG4105M00 molybdopterin converting factor, subunit 1 HR071_RS21300 ENOG4108ZAF Molybdopterin HR071_RS21305 ENOG4105HFZ Membrane HR071_RS21310 ENOG410733J conserved inner membrane protein HR071_RS21315 ENOG4107UXM Membrane HR071_RS21320 ENOG4105DZQ phospholipase D Transphosphatidylase HR071_RS21325 ENOG4105X23 Endonuclease Exonuclease phosphatase HR071_RS21330 ENOG4105I9U inner membrane protein ybhQ HR071_RS21335 ENOG4107QWP ABC-2 type transporter HR071_RS21340 ENOG4107QWP ABC-2 type transporter HR071_RS21345 ENOG4105CJ1 ABC, transporter HR071_RS21355 ENOG4107MVR Transcriptional regulator HR071_RS21360 ENOG4105C1J atp-dependent rna helicase HR071_RS21370 ENOG4105DVT helicase HR071_RS21375 ENOG4108MTB glycosyl transferase family HR071_RS21380 ENOG4105DG4 malate L-lactate dehydrogenase HR071_RS21385 ENOG4105VR4 UPF0379 protein ybiJ HR071_RS21390 ENOG4105KSC Transcriptional regulator, TraR DksA family HR071_RS21395 ENOG4107E2E PKHD-type hydroxylase HR071_RS21405 ENOG4105ZY9 UPF0379 protein ybiM HR071_RS21415 ENOG4105D8X mechanosensitive ion channel HR071_RS21420 ENOG4105CDA abc transporter atp-binding protein HR071_RS21425 ENOG4105E5Q amino acid AbC transporter HR071_RS21430 ENOG4107R0W ABC transporter HR071_RS21440 ENOG4107AQZ Membrane HR071_RS21450 ENOG4108T1M outer membrane protein x HR071_RS21455 ENOG4108I6E Sulfatase HR071_RS21465 ENOG4105KST dependent repressor HR071_RS21470 ENOG4105F4P )-transporter HR071_RS21475 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HR071_RS21480 ENOG4105C5H ABC transporter HR071_RS21485 ENOG4108HCJ Hydrolase HR071_RS21495 ENOG4105F1A Pyruvate formate-lyase HR071_RS21500 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) HR071_RS21505 ENOG4105D06 uba thif-type nad fad binding protein HR071_RS21510 ENOG4105CVM Molybdenum cofactor synthesis domain protein HR071_RS21515 ENOG4105D44 asparaginase HR071_RS21520 ENOG4108JQ6 ABC transporter HR071_RS21540 ENOG4105BZU Histidine kinase HR071_RS21545 ENOG41064RH membrane protein YliF HR071_RS21555 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway HR071_RS21560 ENOG4105D8V Glucose sorbosone dehydrogenase HR071_RS21565 ENOG4108TGY Glutathione S-transferase HR071_RS21570 ENOG4105DZ1 carboxypeptidase HR071_RS21575 ENOG4107FB0 transcriptional regulator DeoR family HR071_RS21580 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HR071_RS21585 ENOG4107QF7 multi-drug HR071_RS21595 ENOG4108HCJ Hydrolase HR071_RS21600 ENOG4106UW1 Major Facilitator superfamily HR071_RS21605 ENOG4108RFG Tetr family transcriptional regulator HR071_RS21615 ENOG4105GWF inner membrane protein YbjM HR071_RS21620 ENOG41090BQ Glutaredoxin HR071_RS21625 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress HR071_RS21630 ENOG4108DBC nitroreductase HR071_RS21640 ENOG4108RMJ sensory transduction regulator HR071_RS21645 ENOG4107RUE extracellular solute-binding protein family 1 HR071_RS21650 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HR071_RS21655 ENOG4105F38 ABC transporter, permease HR071_RS21660 ENOG4105D38 putrescine abc transporter HR071_RS21665 ENOG4105RBQ inner membrane protein ybjO HR071_RS21675 ENOG4106TNF Periplasmic binding protein HR071_RS21680 ENOG4105DMR ABC, transporter HR071_RS21685 ENOG4105GBT ABC transporter HR071_RS21690 ENOG4106PMH Extracellular solute-binding protein family 3 HR071_RS21695 ENOG4105E5Z arginine transporter ATP-binding subunit HR071_RS21700 ENOG41064MM (LipO)protein HR071_RS21710 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HR071_RS21715 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HR071_RS21720 ENOG4105CGD Nad-dependent epimerase dehydratase HR071_RS21725 ENOG4105C5W Aldolase HR071_RS21730 ENOG4105C7K acetolactate synthase HR071_RS21735 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HR071_RS21740 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) HR071_RS21745 ENOG4105DWU Membrane HR071_RS21750 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) HR071_RS21755 ENOG4105CPB ATP-dependent endonuclease of the OLD family HR071_RS21760 ENOG4108MJ5 VirK protein HR071_RS21765 ENOG4105DJY efflux transporter, rnd family, mfp subunit HR071_RS21775 ENOG4105VEQ Cold shock protein HR071_RS21785 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HR071_RS21795 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) HR071_RS21805 ENOG4108JJ8 (ABC) transporter HR071_RS21810 ENOG4108JJ9 ABC, transporter HR071_RS21815 ENOG4105C3M thioredoxin reductase HR071_RS21825 ENOG4105CNU cell division protein FtsK HR071_RS21835 ENOG4105D1H recombination factor protein RarA HR071_RS21845 ENOG4107QY8 reductase HR071_RS21850 ENOG4105QAX Iron-sulfur HR071_RS21855 ENOG4107KGK dmso reductase anchor subunit HR071_RS21860 ENOG4105CHJ isochorismatase hydrolase HR071_RS21865 ENOG4108ISG Major Facilitator HR071_RS21870 ENOG4105F1A Pyruvate formate-lyase HR071_RS21875 ENOG4105C6N Formate acetyltransferase HR071_RS21880 ENOG4105TMB Formate nitrite transporter HR071_RS21885 ENOG4105DDY UPF0142 protein ycaO HR071_RS21890 ENOG4107VMU Membrane HR071_RS21905 ENOG4108K0D peptidase, M48 HR071_RS21915 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HR071_RS21925 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 HR071_RS21930 ENOG4105BZ1 (ABC) transporter HR071_RS21940 ENOG4105T0Z Conserved Protein HR071_RS21955 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups HR071_RS21960 ENOG4107S90 membrAne HR071_RS21965 ENOG4106371 Methyltransferase HR071_RS21975 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) HR071_RS21980 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) HR071_RS21985 ENOG4105DIT ErfK YbiS YcfS YnhG family protein HR071_RS21990 ENOG4105EAQ (twin-arginine translocation) pathway signal HR071_RS21995 ENOG4105C5X domain protein HR071_RS22000 ENOG4105CGF Aromatic amino acid aminotransferase HR071_RS22020 ENOG4105CD8 aminopeptidase N HR071_RS22025 ENOG4105E2Y ABC, transporter HR071_RS22030 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HR071_RS22040 ENOG4105GVF (ABC) transporter HR071_RS22045 ENOG4108UZX fmn reductase HR071_RS22055 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) HR071_RS22060 ENOG4105QVC MOSC domain-containing protein HR071_RS22070 ENOG4105C5H ABC transporter HR071_RS22075 ENOG4105F1S paraquat-inducible protein a HR071_RS22080 ENOG4105DY2 Paraquat-inducible protein b HR071_RS22085 ENOG4108Q2G (LipO)protein HR071_RS22090 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) HR071_RS22100 ENOG4105DAN ATP-dependent protease HR071_RS22110 ENOG4105UYK outer membrane protein a HR071_RS22120 ENOG4108RZ1 DNA transformation protein HR071_RS22125 ENOG4105EM2 membrane HR071_RS22130 ENOG410901E Membrane HR071_RS22135 ENOG41088T4 Helicase IV HR071_RS22150 ENOG4105K4P CoA-binding domain protein HR071_RS22165 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 HR071_RS22170 ENOG4108Z0T Part of a sulfur-relay system (By similarity) HR071_RS22175 ENOG4108MN8 Membrane HR071_RS22185 ENOG4105E3S small subunit HR071_RS22190 ENOG4105DPX Hydrogenase, large subunit HR071_RS22195 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit HR071_RS22200 ENOG4108USZ hydrogenase HR071_RS22205 ENOG4108VXY Hydrogenase-1 operon protein HyaE HR071_RS22210 ENOG4105MVP hydrogenase-1 operon protein HyaF HR071_RS22215 ENOG4105C4M (Ubiquinol oxidase) subunit I HR071_RS22220 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HR071_RS22230 ENOG4105D6F Phosphatase HR071_RS22235 ENOG41060EU Cold shock-like protein HR071_RS22240 ENOG4105VEQ Cold shock protein HR071_RS22255 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation HR071_RS22260 ENOG4105HEE Binding Domain protein HR071_RS22265 ENOG4105BZU Histidine kinase HR071_RS22270 ENOG4108SV3 Tmao reductase system periplasmic protein tort HR071_RS22275 ENOG4106WF9 DNA-binding transcriptional regulator TorR HR071_RS22280 ENOG4105CUW cytochrome C-TYPE protein HR071_RS22285 ENOG4108EM1 reductase HR071_RS22305 ENOG4105D6F Phosphatase HR071_RS22310 ENOG4105XH3 HR071_RS22320 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 HR071_RS22325 ENOG4105C2W permease HR071_RS22360 ENOG4108R86 Transcriptional regulator HR071_RS22365 ENOG4105C26 Dehydrogenase HR071_RS22375 ENOG4105CK7 Sodium proline symporter HR071_RS22380 ENOG4105EKT )-iron permease HR071_RS22390 ENOG4105DBE peroxidase HR071_RS22395 ENOG4105D5M phosphate starvation-inducible protein HR071_RS22405 ENOG4105CND Glycosyl transferase, family 2 HR071_RS22410 ENOG4107BJW polysaccharide deacetylase HR071_RS22415 ENOG4108TUY outer membrane protein PgaA HR071_RS22420 ENOG4105BZU Histidine kinase HR071_RS22440 ENOG4107XHZ cytoplasmic chaperone TorD family protein HR071_RS22445 ENOG4108UQ5 membrane protein YcdZ HR071_RS22450 ENOG4105P8Q Curli production assembly transport component CsgG HR071_RS22455 ENOG4108WYR Curli production assembly transport component, CsgF HR071_RS22460 ENOG4108XDW curli assembly protein CsgE HR071_RS22465 ENOG41086KC Transcriptional regulator HR071_RS22470 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers HR071_RS22475 ENOG41090QH cryptic curlin major subunit HR071_RS22490 ENOG4108UVJ appr-1-p processing domain protein HR071_RS22495 ENOG4107RZC phospholipase d HR071_RS22510 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) HR071_RS22515 ENOG4105NAC (LipO)protein HR071_RS22520 ENOG4108W47 Acidic protein msyB HR071_RS22530 ENOG4105D1S lipid A biosynthesis HR071_RS22540 ENOG4108YYC ycei family HR071_RS22545 ENOG4105DS1 cytochrome b561 HR071_RS22550 ENOG4106974 biofilm formation HR071_RS22560 ENOG4105PVA Biofilm formation regulatory protein BssS HR071_RS22565 ENOG4105MEA DNA damage-inducible protein i HR071_RS22575 ENOG4105F3T (LipO)protein HR071_RS22580 ENOG4105E9S glutaredoxin 2 HR071_RS22590 ENOG4105D9U N-acetyltransferase HR071_RS22600 ENOG4105EP9 oxidoreductase HR071_RS22605 ENOG4105CJR Integral membrane protein (MviN HR071_RS22610 ENOG4105QVD Flagella synthesis protein FlgN HR071_RS22615 ENOG4105M9M anti-sigma28 factor FlgM HR071_RS22620 ENOG4105CKS Flagella basal body P-ring formation protein flgA HR071_RS22625 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) HR071_RS22630 ENOG4108ZC9 flagellar basal-body rod protein flgc HR071_RS22635 ENOG4105W00 Flagellar hook capping protein HR071_RS22640 ENOG4105BZE flagellar hook protein, FlgE HR071_RS22645 ENOG4108KPB Flagellar basal-body rod protein FlgF HR071_RS22650 ENOG4105CGA flagellar basal-body rod protein FlgG HR071_RS22665 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj HR071_RS22670 ENOG4105E1Q flagellar hook-associated protein HR071_RS22675 ENOG4105DTJ flagellar hook-associated protein HR071_RS22680 ENOG4107QQB Ribonuclease E HR071_RS22685 ENOG4105EI2 Pseudouridine synthase HR071_RS22690 ENOG4108UHJ MAF-like protein HR071_RS22695 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HR071_RS22715 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HR071_RS22720 ENOG4105CHR reductase HR071_RS22725 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) HR071_RS22730 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) HR071_RS22735 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HR071_RS22740 ENOG4105HHA aminodeoxychorismate lyase HR071_RS22750 ENOG4107QRG dna polymerase iii HR071_RS22755 ENOG4105F8V Hydrolase, tatD family HR071_RS22760 ENOG4105CI1 PTS System HR071_RS22765 ENOG4105CNM Receptor HR071_RS22770 ENOG4105K59 histidine triad (HIT) protein HR071_RS22775 ENOG41090DQ Lipoprotein HR071_RS22780 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) HR071_RS22785 ENOG4108RUM thiamine kinase HR071_RS22800 ENOG4105CEP NADH dehydrogenase HR071_RS22805 ENOG4107MBR 17 kDa surface antigen HR071_RS22810 ENOG4108IND Tetr family transcriptional regulator HR071_RS22815 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction HR071_RS22820 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HR071_RS22825 ENOG4108JA2 transcriptioN-repair coupling factor HR071_RS22830 ENOG4105IQC Inner membrane protein YcfT HR071_RS22835 ENOG4105D60 lipoprotein releasing system transmembrane protein HR071_RS22840 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HR071_RS22845 ENOG4105D60 lipoprotein releasing system transmembrane protein HR071_RS22855 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HR071_RS22870 ENOG4107RUE extracellular solute-binding protein family 1 HR071_RS22875 ENOG4105D38 putrescine abc transporter HR071_RS22885 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HR071_RS22895 ENOG4105EZE Cupin 4 family protein HR071_RS22900 ENOG4105IFJ Histidine kinase HR071_RS22905 ENOG4105XJC Two component transcriptional regulator (Winged helix family HR071_RS22910 ENOG4107QTF adenylosuccinate lyase HR071_RS22935 ENOG4108HMX isocitrate dehydrogenase (NADP) HR071_RS22940 ENOG4108I1J Integrase HR071_RS23025 ENOG4105TNG K13735 adhesin invasin HR071_RS23040 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi HR071_RS23045 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 HR071_RS23050 ENOG4105RWQ Protein of unknown function (DUF1364) HR071_RS23085 ENOG4105QYK bacteriophage lambda Bor protein homolog HR071_RS23100 ENOG4105FKG DNA packaging protein HR071_RS23105 ENOG4105UZW Tail fiber assembly protein HR071_RS23110 ENOG4107DE1 head-to-tail joining protein HR071_RS23120 ENOG4105F7J membrane-bound serine protease HR071_RS23130 ENOG4105IM0 capsid protein HR071_RS23200 ENOG4108X9F tail fiber protein HR071_RS23215 ENOG4105CC5 ABC transporter HR071_RS23220 ENOG4105CC5 ABC transporter HR071_RS23225 ENOG4105DIK (ABC) transporter HR071_RS23240 ENOG4108HMX isocitrate dehydrogenase (NADP) HR071_RS23250 ENOG41064WM Uncharacterized protein YcgX HR071_RS23255 ENOG4108XDN Transcriptional regulator HR071_RS23260 ENOG4105BZU Histidine kinase HR071_RS23265 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component HR071_RS23270 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB HR071_RS23280 ENOG410738I uncharacterized protein ymgC HR071_RS23305 ENOG410658X HR071_RS23340 ENOG4107QMS site-determining protein HR071_RS23350 ENOG4105S66 prophage protein HR071_RS23355 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium HR071_RS23365 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HR071_RS23370 ENOG4108ZZ3 UPF0260 protein HR071_RS23375 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells HR071_RS23380 ENOG4105KT5 UmuD protein HR071_RS23385 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HR071_RS23395 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) HR071_RS23405 ENOG4105ED1 spovr family HR071_RS23415 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HR071_RS23425 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A HR071_RS23435 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) HR071_RS23455 ENOG4108BSC Methyltransferase HR071_RS23460 ENOG4105E0A ABC, transporter HR071_RS23465 ENOG4105EHG Permease protein HR071_RS23470 ENOG4105S10 periplasmic binding protein HR071_RS23480 ENOG4105VDH Dihydroxyacetone kinase HR071_RS23485 ENOG4108UTZ Dihydroxyacetone kinase HR071_RS23490 ENOG4105CMT Dihydroxyacetone kinase HR071_RS23495 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family HR071_RS23540 ENOG4105HVQ Regulatory factor of maltose metabolism HR071_RS23560 ENOG4108XS9 dna repair protein HR071_RS23565 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HR071_RS23635 ENOG4105DFP Integrase HR071_RS23640 ENOG4105C3G gtp-binding protein HR071_RS23650 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria HR071_RS23655 ENOG4105CHH sulfate transporter HR071_RS23660 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HR071_RS23670 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) HR071_RS23685 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HR071_RS23690 ENOG4108YY7 Invasion gene expression up-regulator SirB HR071_RS23695 ENOG41063JG Transcriptional regulator HR071_RS23710 ENOG4105EWV Sodium calcium exchanger membrane region HR071_RS23715 ENOG4105WS7 Cation transport regulator HR071_RS23720 ENOG4108NH8 Cation transport protein HR071_RS23725 ENOG41090EX DsrE family HR071_RS23730 ENOG4105ID0 Putative invasin HR071_RS23735 ENOG4105WH1 Two component transcriptional regulator luxr family HR071_RS23740 ENOG4105BZU Histidine kinase HR071_RS23745 ENOG4105DQQ Major facilitator superfamily MFS_1 HR071_RS23750 ENOG4105CRU nitrate reductase, alpha subunit HR071_RS23755 ENOG4108IUE nitrate reductase beta subunit HR071_RS23760 ENOG4105R3A Nitrate reductase HR071_RS23765 ENOG41076YT nitrate reductase, gamma subunit HR071_RS23770 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) HR071_RS23775 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase HR071_RS23815 ENOG4105CIY formyltetrahydrofolate deformylase HR071_RS23825 ENOG4105D78 K07001 NTE family protein HR071_RS23830 ENOG4105I93 response regulator HR071_RS23835 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HR071_RS23840 ENOG4108SAU DNA-binding protein H-ns HR071_RS23845 ENOG4107104 thymidine kinase HR071_RS23855 ENOG4105C0A alcohol dehydrogenase HR071_RS23860 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein HR071_RS23865 ENOG4108J59 Extracellular solute-binding protein, family 5 HR071_RS23870 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component HR071_RS23875 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HR071_RS23880 ENOG4105C3U ABC transporter HR071_RS23885 ENOG4108JQ7 (ABC) transporter HR071_RS23905 ENOG4107SVH Potassium channel protein HR071_RS23910 ENOG4105K9H YciI-like protein HR071_RS23915 ENOG410822N TonB family HR071_RS23920 ENOG4105NAU thioesterase Superfamily protein HR071_RS23940 ENOG4105EIF outer membrane protein W HR071_RS23945 ENOG4108I1J Integrase HR071_RS23960 ENOG4106G8A Qin prophage HR071_RS23970 ENOG4106050 phage regulatory protein, rha family HR071_RS24090 ENOG4108MXB Protein of unknown function (DUF968) HR071_RS24095 ENOG4105KSK (crossover) junction endodeoxyribonuclease HR071_RS24100 ENOG4105HGD Antitermination protein HR071_RS24145 ENOG4105QFS Lysis protein S homolog from lambdoid prophage HR071_RS24180 ENOG4106YSC HR071_RS24225 ENOG4107ENK receptor HR071_RS24255 ENOG4108YXQ IS66 Orf2 family protein HR071_RS24270 ENOG4105EKQ RNA-directed DNA polymerase HR071_RS24290 ENOG41063SR receptor HR071_RS24360 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HR071_RS24365 ENOG4107R39 (ABC) transporter HR071_RS24370 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HR071_RS24385 ENOG4107SJW iron permease, FTR1 HR071_RS24390 ENOG4108BUD transposase HR071_RS24415 ENOG4108BUD transposase HR071_RS24420 ENOG4108YXQ IS66 Orf2 family protein HR071_RS24445 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HR071_RS24450 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) HR071_RS24455 ENOG4108BUD transposase HR071_RS24465 ENOG4105BZU Histidine kinase HR071_RS24495 ENOG4108VSE mercuric transport protein HR071_RS24500 ENOG4105W1Y Transcriptional regulator HR071_RS24525 ENOG4106CQM replication HR071_RS24535 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) HR071_RS24550 ENOG4105KK6 nuclease HR071_RS24565 ENOG4107CBI conjugal transfer fertility inhibition protein HR071_RS24570 ENOG4107U2T alpha beta HR071_RS24810 ENOG4105FEQ ParB domain protein nuclease HR071_RS24860 ENOG4106JQ7 HR071_RS24865 ENOG41073YN Protein of unknown function (DUF1380)