locus-tag	class	description
GVI77_RS00010	COG0592	DNA-directed DNA polymerase activity
GVI77_RS00020	COG0187	DNA topoisomerase II activity
GVI77_RS00025	COG3753	Protein conserved in bacteria
GVI77_RS00030	COG0561	phosphatase activity
GVI77_RS00040	COG2186	Transcriptional regulator
GVI77_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
GVI77_RS00050	COG0800	Aldolase
GVI77_RS00060	COG2271	Major facilitator Superfamily
GVI77_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
GVI77_RS00075	COG5645	(Lipo)protein
GVI77_RS00095	COG2207	Transcriptional regulator
GVI77_RS00100	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GVI77_RS00105	COG3119	arylsulfatase activity
GVI77_RS00110	COG2149	membrane
GVI77_RS00120	COG0641	radical SAM
GVI77_RS00125	COG2814	Major facilitator Superfamily
GVI77_RS00135	COG0028	Belongs to the TPP enzyme family
GVI77_RS00140	COG0440	acetolactate synthase activity
GVI77_RS00155	COG2197	response regulator
GVI77_RS00160	COG3851	Histidine kinase
GVI77_RS00165	COG2271	Major facilitator Superfamily
GVI77_RS00170	COG2271	Major facilitator Superfamily
GVI77_RS00180	COG2252	PERMEase
GVI77_RS00210	COG1464	Belongs to the NlpA lipoprotein family
GVI77_RS00215	COG0697	spore germination
GVI77_RS00235	COG2211	Major facilitator Superfamily
GVI77_RS00240	COG1501	Belongs to the glycosyl hydrolase 31 family
GVI77_RS00245	COG3711	transcriptional antiterminator
GVI77_RS00250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS00250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS00250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS00255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS00260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS00260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS00275	COG1940	carbohydrate kinase activity
GVI77_RS00285	COG2982	Protein involved in outer membrane biogenesis
GVI77_RS00290	COG2233	PERMEase
GVI77_RS00295	COG0786	glutamate:sodium symporter activity
GVI77_RS00300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GVI77_RS00305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GVI77_RS00310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GVI77_RS00320	COG0194	GDP metabolic process
GVI77_RS00325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GVI77_RS00330	COG2860	membrane
GVI77_RS00335	COG1561	YicC-like family, N-terminal region
GVI77_RS00360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GVI77_RS00390	COG1519	Transferase
GVI77_RS00395	COG0859	PFAM glycosyl transferase family 9
GVI77_RS00400	COG0438	transferase activity, transferring glycosyl groups
GVI77_RS00405	COG0515	serine threonine protein kinase
GVI77_RS00410	COG4641	Protein conserved in bacteria
GVI77_RS00410	COG0438	transferase activity, transferring glycosyl groups
GVI77_RS00415	COG0438	transferase activity, transferring glycosyl groups
GVI77_RS00420	COG1442	glycosyl transferase family 8
GVI77_RS00425	COG1442	glycosyl transferase family 8
GVI77_RS00430	COG3642	lipopolysaccharide core region biosynthetic process
GVI77_RS00440	COG0859	PFAM glycosyl transferase family 9
GVI77_RS00445	COG3307	-O-antigen
GVI77_RS00450	COG0859	PFAM glycosyl transferase family 9
GVI77_RS00455	COG0859	PFAM glycosyl transferase family 9
GVI77_RS00465	COG0156	8-amino-7-oxononanoate synthase activity
GVI77_RS00475	COG1216	Glycosyl transferase, family 2
GVI77_RS00480	COG2861	carbohydrate metabolic process
GVI77_RS00485	COG4942	peptidase
GVI77_RS00495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GVI77_RS00500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GVI77_RS00515	COG1045	serine acetyltransferase
GVI77_RS00520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GVI77_RS00530	COG2186	Transcriptional regulator
GVI77_RS00535	COG1620	l-lactate permease
GVI77_RS00540	COG5295	Hep Hag repeat protein
GVI77_RS00560	COG3722	fumarate hydratase activity
GVI77_RS00570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS00570	COG2213	PTS system mannitol-specific
GVI77_RS00580	COG1566	PFAM secretion protein HlyD family protein
GVI77_RS00585	COG0625	glutathione transferase activity
GVI77_RS00595	COG3276	selenocysteine insertion sequence binding
GVI77_RS00600	COG1454	alcohol dehydrogenase
GVI77_RS00610	COG1012	belongs to the aldehyde dehydrogenase family
GVI77_RS00620	COG2211	Major facilitator Superfamily
GVI77_RS00630	COG0235	Class ii aldolase
GVI77_RS00635	COG3623	hexulose-6-phosphate isomerase
GVI77_RS00640	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GVI77_RS00645	COG1070	Carbohydrate kinase
GVI77_RS00650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GVI77_RS00655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GVI77_RS00660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GVI77_RS00670	COG2731	YhcH YjgK YiaL family protein
GVI77_RS00680	COG1414	Transcriptional regulator
GVI77_RS00685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS00690	COG3977	Valine--pyruvate aminotransferase
GVI77_RS00695	COG0366	Alpha amylase catalytic
GVI77_RS00700	COG2992	FlgJ-related protein
GVI77_RS00705	COG1609	Transcriptional regulator
GVI77_RS00705	COG2207	Transcriptional regulator
GVI77_RS00710	COG4214	carbohydrate transport
GVI77_RS00720	COG4213	ABC transporter substrate-binding protein
GVI77_RS00730	COG1070	Carbohydrate kinase
GVI77_RS00735	COG4682	membrane
GVI77_RS00740	COG4682	membrane
GVI77_RS00745	COG3274	enterobacterial common antigen metabolic process
GVI77_RS00775	COG1278	Cold shock
GVI77_RS00780	COG2944	sequence-specific DNA binding
GVI77_RS00795	COG2885	chlorophyll binding
GVI77_RS00800	COG0243	molybdopterin cofactor binding
GVI77_RS00805	COG0456	acetyltransferase
GVI77_RS00810	COG2818	Glycosylase
GVI77_RS00815	COG5571	outer membrane autotransporter
GVI77_RS00820	COG2223	nitrite transmembrane transporter activity
GVI77_RS00825	COG2194	sulfuric ester hydrolase activity
GVI77_RS00835	COG0747	negative chemotaxis
GVI77_RS00840	COG0601	transmembrane transport
GVI77_RS00845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GVI77_RS00850	COG0444	Belongs to the ABC transporter superfamily
GVI77_RS00855	COG4608	Belongs to the ABC transporter superfamily
GVI77_RS00865	COG3550	peptidyl-serine autophosphorylation
GVI77_RS00870	COG3550	peptidyl-serine autophosphorylation
GVI77_RS00875	COG0814	amino acid
GVI77_RS00920	COG1215	transferase activity, transferring glycosyl groups
GVI77_RS00925	COG1215	transferase activity, transferring glycosyl groups
GVI77_RS00930	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GVI77_RS00935	COG0457	Tetratricopeptide repeat
GVI77_RS00935	COG3118	belongs to the thioredoxin family
GVI77_RS00940	COG2200	EAL domain
GVI77_RS00940	COG2199	diguanylate cyclase activity
GVI77_RS00950	COG0612	Peptidase, M16
GVI77_RS00955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS00960	COG2200	EAL domain
GVI77_RS00965	COG2982	Protein involved in outer membrane biogenesis
GVI77_RS00970	COG0477	Major facilitator Superfamily
GVI77_RS00975	COG1295	ribonuclease BN
GVI77_RS00980	COG0583	DNA-binding transcription factor activity
GVI77_RS00985	COG2197	response regulator
GVI77_RS00995	COG1858	cytochrome C peroxidase
GVI77_RS01000	COG0076	glutamate decarboxylase activity
GVI77_RS01005	COG2207	Transcriptional regulator
GVI77_RS01010	COG2207	Transcriptional regulator
GVI77_RS01020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI77_RS01025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS01035	COG2771	luxR family
GVI77_RS01040	COG3247	response to pH
GVI77_RS01055	COG1285	pathogenesis
GVI77_RS01065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS01075	COG3721	Heme iron utilization protein
GVI77_RS01090	COG4771	TonB-dependent receptor
GVI77_RS01095	COG3720	iron ion transport
GVI77_RS01100	COG2197	response regulator
GVI77_RS01105	COG3065	identical protein binding
GVI77_RS01115	COG1393	Belongs to the ArsC family
GVI77_RS01125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GVI77_RS01130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GVI77_RS01135	COG0339	signal peptide processing
GVI77_RS01145	COG3104	oligopeptide transport
GVI77_RS01150	COG0589	response to stress
GVI77_RS01160	COG0306	phosphate transporter
GVI77_RS01165	COG2081	HI0933 family
GVI77_RS01175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS01180	COG0842	Transport permease protein
GVI77_RS01180	COG1129	ABC transporter
GVI77_RS01185	COG0842	Transport permease protein
GVI77_RS01190	COG0191	fructose-bisphosphate aldolase activity
GVI77_RS01205	COG3775	system Galactitol-specific IIC component
GVI77_RS01210	COG3414	Phosphotransferase system galactitol-specific IIB component
GVI77_RS01220	COG2188	Transcriptional regulator
GVI77_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GVI77_RS01245	COG0601	transmembrane transport
GVI77_RS01250	COG0747	negative chemotaxis
GVI77_RS01255	COG2091	lysine biosynthetic process via aminoadipic acid
GVI77_RS01260	COG0628	permease
GVI77_RS01265	COG0477	Major facilitator Superfamily
GVI77_RS01275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GVI77_RS01290	COG3714	YhhN family
GVI77_RS01300	COG3776	membrane
GVI77_RS01305	COG0742	ribosomal rna small subunit methyltransferase
GVI77_RS01310	COG0552	protein localization to endoplasmic reticulum
GVI77_RS01315	COG2884	Cell division ATP-binding protein ftsE
GVI77_RS01320	COG2177	Part of the ABC transporter FtsEX involved in
GVI77_RS01325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GVI77_RS01330	COG0683	leucine binding
GVI77_RS01345	COG0456	acetyltransferase
GVI77_RS01350	COG0683	leucine binding
GVI77_RS01355	COG0559	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS01360	COG4177	L-phenylalanine transmembrane transporter activity
GVI77_RS01365	COG0411	ABC transporter
GVI77_RS01370	COG0410	ABC transporter
GVI77_RS01395	COG0584	glycerophosphoryl diester phosphodiesterase
GVI77_RS01405	COG0405	Gamma-glutamyltransferase
GVI77_RS01410	COG1247	-acetyltransferase
GVI77_RS01415	COG0673	inositol 2-dehydrogenase activity
GVI77_RS01420	COG1741	Belongs to the pirin family
GVI77_RS01425	COG1609	Transcriptional regulator
GVI77_RS01430	COG3265	gluconokinase activity
GVI77_RS01435	COG2610	gluconate transmembrane transporter activity
GVI77_RS01440	COG0514	ATP-dependent DNA helicase (RecQ)
GVI77_RS01450	COG2095	MarC family integral membrane protein
GVI77_RS01455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GVI77_RS01480	COG0058	SHG alpha-glucan phosphorylase activity
GVI77_RS01485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GVI77_RS01500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GVI77_RS01515	COG1349	DNA-binding transcription factor activity
GVI77_RS01520	COG4650	regulator
GVI77_RS01535	COG0058	SHG alpha-glucan phosphorylase activity
GVI77_RS01540	COG1640	4-alpha-glucanotransferase
GVI77_RS01545	COG2610	gluconate transmembrane transporter activity
GVI77_RS01560	COG0596	Alpha beta hydrolase
GVI77_RS01575	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GVI77_RS01580	COG1918	ferrous iron import across plasma membrane
GVI77_RS01585	COG2183	response to ionizing radiation
GVI77_RS01590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GVI77_RS01610	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GVI77_RS01630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GVI77_RS01635	COG1011	Hydrolase
GVI77_RS01645	COG0494	nUDIX hydrolase
GVI77_RS01650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GVI77_RS01655	COG4972	Pilus assembly protein
GVI77_RS01660	COG3166	PFAM Fimbrial assembly family protein
GVI77_RS01675	COG4796	Type ii and iii secretion system protein
GVI77_RS01690	COG3266	domain, Protein
GVI77_RS01695	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GVI77_RS01700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GVI77_RS01710	COG0180	Tryptophanyl-tRNA synthetase
GVI77_RS01715	COG2188	Transcriptional regulator
GVI77_RS01725	COG3457	Alanine racemase
GVI77_RS01730	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GVI77_RS01735	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GVI77_RS01750	COG0626	cystathionine gamma-synthase activity
GVI77_RS01765	COG2116	formate transmembrane transporter activity
GVI77_RS01770	COG2146	nitrite reductase [NAD(P)H] activity
GVI77_RS01775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GVI77_RS01785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GVI77_RS01795	COG2184	nucleotidyltransferase activity
GVI77_RS01800	COG0512	Glutamine amidotransferase of anthranilate synthase
GVI77_RS01805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GVI77_RS01810	COG1289	transmembrane transporter activity
GVI77_RS01815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GVI77_RS01820	COG1765	OsmC-like protein
GVI77_RS01825	COG3954	Phosphoribulokinase
GVI77_RS01835	COG0429	hydrolase of the alpha beta-hydrolase fold
GVI77_RS01840	COG0488	(ABC) transporter
GVI77_RS01855	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GVI77_RS01860	COG1047	Peptidyl-prolyl cis-trans
GVI77_RS01870	COG0545	Peptidyl-prolyl cis-trans isomerase
GVI77_RS01875	COG2964	Protein conserved in bacteria
GVI77_RS01915	COG3979	chitinase
GVI77_RS01920	COG2906	2 iron, 2 sulfur cluster binding
GVI77_RS01925	COG2193	ferroxidase activity
GVI77_RS01930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GVI77_RS01935	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GVI77_RS01940	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GVI77_RS01945	COG3156	type II secretion system protein K
GVI77_RS01950	COG4795	General secretion pathway protein
GVI77_RS01955	COG2165	general secretion pathway protein
GVI77_RS01960	COG2165	general secretion pathway protein
GVI77_RS01965	COG2165	general secretion pathway protein
GVI77_RS01970	COG1459	type II secretion system
GVI77_RS01975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GVI77_RS01980	COG1450	Type ii and iii secretion system protein
GVI77_RS01985	COG3031	protein transport across the cell outer membrane
GVI77_RS01990	COG3267	Type II secretory pathway component ExeA
GVI77_RS01990	COG3409	Peptidoglycan-binding domain 1 protein
GVI77_RS02015	COG0089	rRNA binding
GVI77_RS02105	COG0201	protein transport
GVI77_RS02145	COG0789	Transcriptional regulator
GVI77_RS02150	COG3036	rescue of stalled ribosome
GVI77_RS02160	COG0569	domain protein
GVI77_RS02180	COG0758	DNA mediated transformation
GVI77_RS02190	COG0551	DNA topoisomerase type I activity
GVI77_RS02195	COG0009	L-threonylcarbamoyladenylate synthase
GVI77_RS02210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GVI77_RS02250	COG1126	abc transporter atp-binding protein
GVI77_RS02255	COG0765	amino acid transport
GVI77_RS02260	COG4597	amino acid ABC transporter
GVI77_RS02265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS02275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI77_RS02280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS02285	COG1309	transcriptional regulator
GVI77_RS02295	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GVI77_RS02305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GVI77_RS02315	COG4145	pantothenate transmembrane transporter activity
GVI77_RS02320	COG3924	membrane
GVI77_RS02325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS02330	COG1349	DNA-binding transcription factor activity
GVI77_RS02340	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS02345	COG1129	ABC transporter
GVI77_RS02350	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS02355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS02365	COG0439	Biotin carboxylase
GVI77_RS02370	COG0511	ligase activity, forming carbon-carbon bonds
GVI77_RS02375	COG0604	alcohol dehydrogenase
GVI77_RS02380	COG2200	EAL domain
GVI77_RS02380	COG2199	diguanylate cyclase activity
GVI77_RS02385	COG1077	Cell shape determining protein MreB Mrl
GVI77_RS02390	COG1792	Involved in formation and maintenance of cell shape
GVI77_RS02395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GVI77_RS02405	COG1530	ribonuclease E activity
GVI77_RS02410	COG3164	Protein of unknown function
GVI77_RS02415	COG0312	modulator of DNA gyrase
GVI77_RS02420	COG0583	DNA-binding transcription factor activity
GVI77_RS02440	COG2732	(Barnase) inhibitor
GVI77_RS02460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GVI77_RS02465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GVI77_RS02470	COG3105	Protein conserved in bacteria
GVI77_RS02475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GVI77_RS02490	COG0625	glutathione transferase activity
GVI77_RS02495	COG2969	positive regulation of protein catabolic process
GVI77_RS02510	COG2814	Major facilitator Superfamily
GVI77_RS02520	COG1940	carbohydrate kinase activity
GVI77_RS02525	COG2731	YhcH YjgK YiaL family protein
GVI77_RS02530	COG0493	'glutamate synthase
GVI77_RS02535	COG0070	glutamate synthase
GVI77_RS02535	COG0067	glutamate synthase
GVI77_RS02535	COG0069	glutamate synthase activity
GVI77_RS02540	COG1242	4 iron, 4 sulfur cluster binding
GVI77_RS02545	COG0784	Response regulator, receiver
GVI77_RS02545	COG2198	Histidine kinase
GVI77_RS02545	COG5002	protein histidine kinase activity
GVI77_RS02550	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GVI77_RS02560	COG0515	serine threonine protein kinase
GVI77_RS02565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS02580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GVI77_RS02585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GVI77_RS02590	COG1137	ATPase activity
GVI77_RS02595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GVI77_RS02600	COG3117	lipopolysaccharide transmembrane transporter activity
GVI77_RS02605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GVI77_RS02610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GVI77_RS02610	COG0517	IMP dehydrogenase activity
GVI77_RS02615	COG0530	calcium, potassium:sodium antiporter activity
GVI77_RS02620	COG1127	ABC transporter
GVI77_RS02625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GVI77_RS02630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GVI77_RS02635	COG2854	intermembrane phospholipid transfer
GVI77_RS02640	COG3113	response to antibiotic
GVI77_RS02645	COG5007	Belongs to the BolA IbaG family
GVI77_RS02655	COG3423	Transcriptional regulator
GVI77_RS02660	COG0142	geranyltranstransferase activity
GVI77_RS02675	COG0697	spore germination
GVI77_RS02685	COG2027	D-alanyl-D-alanine carboxypeptidase
GVI77_RS02690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GVI77_RS02695	COG1534	Rna-binding protein
GVI77_RS02705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GVI77_RS02710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GVI77_RS02720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GVI77_RS02730	COG2194	sulfuric ester hydrolase activity
GVI77_RS02750	COG0195	Participates in both transcription termination and antitermination
GVI77_RS02790	COG0513	Belongs to the DEAD box helicase family
GVI77_RS02795	COG0814	amino acid
GVI77_RS02800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI77_RS02805	COG0826	peptidase U32
GVI77_RS02810	COG0826	peptidase U32
GVI77_RS02815	COG3154	lipid carrier protein
GVI77_RS02820	COG3153	acetyltransferase
GVI77_RS02835	COG0693	protein deglycase activity
GVI77_RS02840	COG0702	epimerase
GVI77_RS02845	COG0701	Predicted permease
GVI77_RS02850	COG2823	Periplasmic or secreted lipoprotein
GVI77_RS02870	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GVI77_RS02875	COG0363	glucosamine-6-phosphate deaminase activity
GVI77_RS02880	COG3716	PTS system mannose fructose sorbose family IID component
GVI77_RS02885	COG3715	PTS system
GVI77_RS02890	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS02900	COG2222	sugar isomerase
GVI77_RS02905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GVI77_RS02910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS02915	COG3716	PTS system mannose fructose sorbose family IID component
GVI77_RS02925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS02935	COG1349	DNA-binding transcription factor activity
GVI77_RS02945	COG2002	toxin-antitoxin pair type II binding
GVI77_RS02950	COG2721	sulfolactate sulfo-lyase activity
GVI77_RS02955	COG2271	Major facilitator Superfamily
GVI77_RS02965	COG2084	Dehydrogenase
GVI77_RS02970	COG1929	Belongs to the glycerate kinase type-1 family
GVI77_RS02985	COG0583	DNA-binding transcription factor activity
GVI77_RS02990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GVI77_RS03000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GVI77_RS03005	COG1882	Formate acetyltransferase
GVI77_RS03010	COG0251	oxidation-reduction process
GVI77_RS03015	COG1760	l-serine dehydratase
GVI77_RS03020	COG0814	amino acid
GVI77_RS03035	COG1741	Belongs to the pirin family
GVI77_RS03040	COG0583	DNA-binding transcription factor activity
GVI77_RS03045	COG3152	Membrane
GVI77_RS03050	COG0435	Glutathione S-transferase
GVI77_RS03055	COG2259	Doxx family
GVI77_RS03065	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GVI77_RS03070	COG4575	ribosome binding
GVI77_RS03075	COG1422	Protein of unknown function (DUF1090)
GVI77_RS03085	COG0586	Pfam SNARE associated Golgi protein
GVI77_RS03090	COG2186	Transcriptional regulator
GVI77_RS03095	COG2271	Major facilitator Superfamily
GVI77_RS03105	COG2721	sulfolactate sulfo-lyase activity
GVI77_RS03120	COG0861	Integral membrane protein TerC family
GVI77_RS03125	COG0673	inositol 2-dehydrogenase activity
GVI77_RS03130	COG2949	membrane
GVI77_RS03135	COG1451	nucleotide metabolic process
GVI77_RS03145	COG4680	protein conserved in bacteria
GVI77_RS03150	COG5499	transcription regulator containing HTH domain
GVI77_RS03155	COG0446	pyridine nucleotide-disulphide oxidoreductase
GVI77_RS03155	COG1902	pentaerythritol trinitrate reductase activity
GVI77_RS03160	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GVI77_RS03160	COG3408	Glycogen debranching enzyme
GVI77_RS03170	COG0531	amino acid
GVI77_RS03175	COG2731	YhcH YjgK YiaL family protein
GVI77_RS03180	COG3250	beta-galactosidase activity
GVI77_RS03185	COG1609	Transcriptional regulator
GVI77_RS03190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GVI77_RS03200	COG0840	transmembrane signaling receptor activity
GVI77_RS03205	COG1695	Transcriptional regulator
GVI77_RS03210	COG2375	cellular response to nickel ion
GVI77_RS03225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GVI77_RS03230	COG0358	DNA primase activity
GVI77_RS03235	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GVI77_RS03245	COG0471	metal ion transport
GVI77_RS03250	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI77_RS03255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI77_RS03270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GVI77_RS03285	COG4991	sh3 domain protein
GVI77_RS03290	COG3025	triphosphatase activity
GVI77_RS03310	COG2268	Band 7 protein
GVI77_RS03315	COG1585	Membrane protein implicated in regulation of membrane protease activity
GVI77_RS03335	COG3539	Fimbrial protein
GVI77_RS03340	COG3121	Chaperone
GVI77_RS03345	COG3188	usher protein
GVI77_RS03350	COG3539	Fimbrial protein
GVI77_RS03365	COG3384	dioxygenase
GVI77_RS03375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GVI77_RS03385	COG0754	glutathionylspermidine amidase activity
GVI77_RS03395	COG1538	Outer membrane efflux protein
GVI77_RS03400	COG0494	nUDIX hydrolase
GVI77_RS03405	COG3151	Protein conserved in bacteria
GVI77_RS03410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GVI77_RS03415	COG3150	esterase
GVI77_RS03420	COG0187	DNA topoisomerase II activity
GVI77_RS03425	COG4774	siderophore transport
GVI77_RS03430	COG1120	ATPase activity
GVI77_RS03435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS03440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS03450	COG1737	Transcriptional regulator
GVI77_RS03455	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GVI77_RS03460	COG2249	NAD(P)H dehydrogenase (quinone) activity
GVI77_RS03475	COG0642	Histidine kinase
GVI77_RS03480	COG0745	RESPONSE REGULATOR receiver
GVI77_RS03485	COG3111	PFAM Bacterial OB fold (BOF) protein
GVI77_RS03490	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GVI77_RS03495	COG4166	transmembrane transport
GVI77_RS03500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GVI77_RS03505	COG0204	Acyl-transferase
GVI77_RS03540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GVI77_RS03545	COG1063	alcohol dehydrogenase
GVI77_RS03550	COG0246	Mannitol dehydrogenase
GVI77_RS03555	COG2186	Transcriptional regulator
GVI77_RS03560	COG1032	radical SAM domain protein
GVI77_RS03565	COG4238	major outer membrane lipoprotein
GVI77_RS03575	COG0656	L-ascorbic acid biosynthetic process
GVI77_RS03580	COG1979	alcohol dehydrogenase
GVI77_RS03585	COG2207	Transcriptional regulator
GVI77_RS03590	COG0586	Pfam SNARE associated Golgi protein
GVI77_RS03595	COG0626	cystathionine gamma-synthase activity
GVI77_RS03600	COG0811	peptide transport
GVI77_RS03605	COG0848	biopolymer transport protein
GVI77_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS03620	COG0667	Aldo Keto reductase
GVI77_RS03635	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GVI77_RS03640	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS03645	COG5557	Pfam Polysulphide reductase, NrfD
GVI77_RS03650	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GVI77_RS03655	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GVI77_RS03660	COG1773	rubredoxin
GVI77_RS03670	COG0298	carbon dioxide binding
GVI77_RS03675	COG0625	glutathione transferase activity
GVI77_RS03680	COG0754	glutathionylspermidine amidase activity
GVI77_RS03685	COG0306	phosphate transporter
GVI77_RS03690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GVI77_RS03695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GVI77_RS03700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GVI77_RS03705	COG2244	polysaccharide biosynthetic process
GVI77_RS03715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GVI77_RS03720	COG0795	lipopolysaccharide-transporting ATPase activity
GVI77_RS03730	COG0156	8-amino-7-oxononanoate synthase activity
GVI77_RS03735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GVI77_RS03745	COG0318	PFAM AMP-dependent synthetase and ligase
GVI77_RS03750	COG0456	acetyltransferase
GVI77_RS03755	COG2186	Transcriptional regulator
GVI77_RS03760	COG0277	FAD linked oxidase domain protein
GVI77_RS03765	COG0277	FAD linked oxidase domain protein
GVI77_RS03770	COG0247	lactate metabolic process
GVI77_RS03775	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GVI77_RS03780	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GVI77_RS03785	COG1620	l-lactate permease
GVI77_RS03790	COG3064	Membrane
GVI77_RS03795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GVI77_RS03815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GVI77_RS03820	COG1459	type II secretion system
GVI77_RS03825	COG2165	general secretion pathway protein
GVI77_RS03855	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GVI77_RS03920	COG4584	PFAM Integrase catalytic
GVI77_RS03975	COG2003	Belongs to the UPF0758 family
GVI77_RS04000	COG2020	methyltransferase activity
GVI77_RS04005	COG3468	outer membrane autotransporter barrel domain protein
GVI77_RS04015	COG4983	Phage plasmid primase, P4 family domain protein
GVI77_RS04050	COG4372	Transposase
GVI77_RS04060	COG3436	PFAM IS66 Orf2 family protein
GVI77_RS04070	COG3385	transposase activity
GVI77_RS04075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GVI77_RS04080	COG1940	carbohydrate kinase activity
GVI77_RS04085	COG2814	Major facilitator Superfamily
GVI77_RS04095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GVI77_RS04100	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GVI77_RS04105	COG2755	lipolytic protein G-D-S-L family
GVI77_RS04105	COG0657	acetylesterase activity
GVI77_RS04125	COG4771	TonB-dependent receptor
GVI77_RS04185	COG3344	reverse transcriptase
GVI77_RS04230	COG0582	viral genome integration into host DNA
GVI77_RS04240	COG1811	Na channel or pump
GVI77_RS04245	COG1982	Orn Lys Arg decarboxylase major
GVI77_RS04250	COG2211	Major facilitator Superfamily
GVI77_RS04265	COG1194	a g-specific adenine glycosylase
GVI77_RS04275	COG3171	Protein conserved in bacteria
GVI77_RS04285	COG0252	asparaginase activity
GVI77_RS04295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GVI77_RS04310	COG0762	integral membrane protein
GVI77_RS04315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GVI77_RS04320	COG2805	Type II/IV secretion system protein
GVI77_RS04335	COG0189	ligase activity
GVI77_RS04340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GVI77_RS04345	COG2356	endonuclease I
GVI77_RS04355	COG2814	Major facilitator Superfamily
GVI77_RS04375	COG1166	arginine decarboxylase activity
GVI77_RS04390	COG0501	Belongs to the peptidase M48B family
GVI77_RS04395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GVI77_RS04400	COG0330	HflC and HflK could
GVI77_RS04405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS04410	COG2213	PTS system mannitol-specific
GVI77_RS04415	COG1063	alcohol dehydrogenase
GVI77_RS04420	COG1494	fructose-1,6-bisphosphatase
GVI77_RS04430	COG1072	(Pantothenic acid kinase))
GVI77_RS04435	COG1122	ATPase activity
GVI77_RS04470	COG0191	fructose-bisphosphate aldolase activity
GVI77_RS04475	COG0668	transmembrane transport
GVI77_RS04480	COG1279	arginine transmembrane transporter activity
GVI77_RS04485	COG2968	Membrane
GVI77_RS04495	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GVI77_RS04495	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GVI77_RS04515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GVI77_RS04525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GVI77_RS04545	COG0006	proline dipeptidase activity
GVI77_RS04550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GVI77_RS04555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GVI77_RS04580	COG2723	6-phospho-beta-galactosidase activity
GVI77_RS04590	COG1272	protein, Hemolysin III
GVI77_RS04600	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GVI77_RS04610	COG0716	FMN binding
GVI77_RS04615	COG4974	Belongs to the 'phage' integrase family
GVI77_RS04620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GVI77_RS04625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GVI77_RS04635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GVI77_RS04655	COG2233	PERMEase
GVI77_RS04660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS04660	COG0493	'glutamate synthase
GVI77_RS04665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS04670	COG2252	PERMEase
GVI77_RS04675	COG0402	S-adenosylhomocysteine deaminase activity
GVI77_RS04680	COG2233	PERMEase
GVI77_RS04685	COG2080	2 iron, 2 sulfur cluster binding
GVI77_RS04685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GVI77_RS04690	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GVI77_RS04695	COG0402	S-adenosylhomocysteine deaminase activity
GVI77_RS04700	COG0493	'glutamate synthase
GVI77_RS04700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS04705	COG2068	MobA-Related Protein
GVI77_RS04710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GVI77_RS04715	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GVI77_RS04715	COG3608	succinylglutamate desuccinylase aspartoacylase
GVI77_RS04720	COG0549	Belongs to the carbamate kinase family
GVI77_RS04730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GVI77_RS04735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GVI77_RS04740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GVI77_RS04745	COG3829	transcription factor binding
GVI77_RS04750	COG2080	2 iron, 2 sulfur cluster binding
GVI77_RS04755	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GVI77_RS04760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GVI77_RS04765	COG4942	peptidase
GVI77_RS04775	COG0814	amino acid
GVI77_RS04780	COG0183	Belongs to the thiolase family
GVI77_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS04795	COG2814	Major facilitator Superfamily
GVI77_RS04800	COG1794	racemase activity, acting on amino acids and derivatives
GVI77_RS04805	COG0583	DNA-binding transcription factor activity
GVI77_RS04815	COG1609	Transcriptional regulator
GVI77_RS04830	COG0667	Aldo Keto reductase
GVI77_RS04840	COG0861	Integral membrane protein TerC family
GVI77_RS04855	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GVI77_RS04870	COG2165	general secretion pathway protein
GVI77_RS04875	COG4795	General secretion pathway protein
GVI77_RS04885	COG4967	type IV pilus modification protein PilV
GVI77_RS04890	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GVI77_RS04895	COG1025	Belongs to the peptidase M16 family
GVI77_RS04900	COG1074	ATP-dependent DNA helicase activity
GVI77_RS04905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GVI77_RS04910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GVI77_RS04910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GVI77_RS04915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GVI77_RS04920	COG3711	transcriptional antiterminator
GVI77_RS04925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS04925	COG1263	PTS System
GVI77_RS04930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GVI77_RS04945	COG4584	PFAM Integrase catalytic
GVI77_RS04950	COG1484	DNA-dependent DNA replication
GVI77_RS05065	COG2885	chlorophyll binding
GVI77_RS05105	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GVI77_RS05110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GVI77_RS05115	COG2166	iron-sulfur cluster assembly
GVI77_RS05120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GVI77_RS05130	COG0583	DNA-binding transcription factor activity
GVI77_RS05135	COG2363	Small membrane protein
GVI77_RS05145	COG1349	DNA-binding transcription factor activity
GVI77_RS05155	COG1070	Carbohydrate kinase
GVI77_RS05165	COG0738	Major facilitator superfamily
GVI77_RS05170	COG0235	Class ii aldolase
GVI77_RS05175	COG1454	alcohol dehydrogenase
GVI77_RS05185	COG1760	l-serine dehydratase
GVI77_RS05190	COG0814	amino acid
GVI77_RS05195	COG1611	Belongs to the LOG family
GVI77_RS05210	COG3098	single-species biofilm formation
GVI77_RS05215	COG0564	pseudouridine synthase activity
GVI77_RS05220	COG0716	FMN binding
GVI77_RS05225	COG2271	Major facilitator Superfamily
GVI77_RS05230	COG4948	Mandelate Racemase Muconate Lactonizing
GVI77_RS05235	COG4948	Mandelate Racemase Muconate Lactonizing
GVI77_RS05240	COG2205	protein histidine kinase activity
GVI77_RS05240	COG3437	response regulator, receiver
GVI77_RS05240	COG4999	Histidine kinase
GVI77_RS05240	COG3850	Histidine kinase
GVI77_RS05250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GVI77_RS05255	COG3956	TIGRFAM MazG family protein
GVI77_RS05270	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GVI77_RS05280	COG0602	queuosine metabolic process
GVI77_RS05310	COG1070	Carbohydrate kinase
GVI77_RS05315	COG2223	nitrite transmembrane transporter activity
GVI77_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS05325	COG0277	FAD linked oxidase domain protein
GVI77_RS05330	COG0477	Major facilitator Superfamily
GVI77_RS05335	COG2086	electron transfer activity
GVI77_RS05340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GVI77_RS05345	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GVI77_RS05350	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GVI77_RS05355	COG0644	oxidoreductase
GVI77_RS05360	COG0720	synthase
GVI77_RS05385	COG2234	aminopeptidase activity
GVI77_RS05425	COG0585	pseudouridine synthase activity
GVI77_RS05440	COG4942	peptidase
GVI77_RS05440	COG1388	LysM domain
GVI77_RS05445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GVI77_RS05460	COG2610	gluconate transmembrane transporter activity
GVI77_RS05465	COG3622	Belongs to the hyi family
GVI77_RS05470	COG0235	Class ii aldolase
GVI77_RS05475	COG3395	kinase activity
GVI77_RS05480	COG2084	Dehydrogenase
GVI77_RS05485	COG1349	DNA-binding transcription factor activity
GVI77_RS05490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GVI77_RS05495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GVI77_RS05510	COG3604	Transcriptional regulator
GVI77_RS05515	COG0309	Hydrogenase expression formation protein (HypE)
GVI77_RS05520	COG0409	Hydrogenase expression formation protein
GVI77_RS05525	COG0298	carbon dioxide binding
GVI77_RS05530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GVI77_RS05535	COG0375	protein maturation
GVI77_RS05545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS05550	COG0651	ATP synthesis coupled electron transport
GVI77_RS05555	COG0650	Formate hydrogenlyase subunit 4
GVI77_RS05560	COG3261	NADH dehydrogenase
GVI77_RS05560	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GVI77_RS05565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GVI77_RS05570	COG3260	NADH ubiquinone oxidoreductase 20
GVI77_RS05580	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GVI77_RS05590	COG5499	transcription regulator containing HTH domain
GVI77_RS05600	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS05605	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GVI77_RS05625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GVI77_RS05625	COG0517	IMP dehydrogenase activity
GVI77_RS05630	COG1349	DNA-binding transcription factor activity
GVI77_RS05635	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS05650	COG3732	PTS system glucitol sorbitol-specific
GVI77_RS05655	COG3730	PTS system glucitol sorbitol-specific
GVI77_RS05660	COG2951	lytic endotransglycosylase activity
GVI77_RS05670	COG1546	Belongs to the CinA family
GVI77_RS05690	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GVI77_RS05720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI77_RS05725	COG1238	metal cluster binding
GVI77_RS05750	COG2814	Major facilitator Superfamily
GVI77_RS05755	COG1566	PFAM secretion protein HlyD family protein
GVI77_RS05760	COG1846	Transcriptional regulator
GVI77_RS05770	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GVI77_RS05775	COG2814	Major facilitator Superfamily
GVI77_RS05780	COG2113	Glycine betaine
GVI77_RS05785	COG4176	ABC-type proline glycine betaine transport system permease component
GVI77_RS05790	COG4175	Glycine betaine
GVI77_RS05795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GVI77_RS05800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GVI77_RS05810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GVI77_RS05815	COG4575	ribosome binding
GVI77_RS05830	COG2916	Histone family protein nucleoid-structuring protein H-NS
GVI77_RS05835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GVI77_RS05840	COG0640	Transcriptional regulator
GVI77_RS05845	COG0401	homolog of Blt101
GVI77_RS05850	COG1652	LysM domain
GVI77_RS05855	COG1802	Transcriptional regulator
GVI77_RS05860	COG1113	amino acid transport
GVI77_RS05865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GVI77_RS05870	COG1012	belongs to the aldehyde dehydrogenase family
GVI77_RS05875	COG0579	oxidoreductase
GVI77_RS05895	COG2867	negative regulation of translational initiation
GVI77_RS05905	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI77_RS05910	COG0497	DNA recombination
GVI77_RS05925	COG4536	flavin adenine dinucleotide binding
GVI77_RS05930	COG4137	Cytochrome C assembly protein
GVI77_RS05935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GVI77_RS05960	COG2885	chlorophyll binding
GVI77_RS05965	COG2199	diguanylate cyclase activity
GVI77_RS05980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GVI77_RS05985	COG1605	Chorismate mutase
GVI77_RS05985	COG0287	Prephenate dehydrogenase
GVI77_RS05990	COG0077	Prephenate dehydratase
GVI77_RS05990	COG1605	Chorismate mutase
GVI77_RS06000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GVI77_RS06005	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI77_RS06010	COG0564	pseudouridine synthase activity
GVI77_RS06020	COG0542	response to heat
GVI77_RS06045	COG0477	Major facilitator Superfamily
GVI77_RS06050	COG5544	Lipoprotein
GVI77_RS06055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GVI77_RS06060	COG0045	succinate-CoA ligase (ADP-forming) activity
GVI77_RS06060	COG1042	CoA-binding domain protein
GVI77_RS06060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI77_RS06065	COG3148	PFAM DTW domain containing protein
GVI77_RS06070	COG3118	belongs to the thioredoxin family
GVI77_RS06075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GVI77_RS06095	COG0583	DNA-binding transcription factor activity
GVI77_RS06100	COG0513	Belongs to the DEAD box helicase family
GVI77_RS06110	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GVI77_RS06120	COG1595	DNA-templated transcription, initiation
GVI77_RS06125	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GVI77_RS06130	COG3026	antisigma factor binding
GVI77_RS06135	COG3086	response to oxidative stress
GVI77_RS06145	COG0681	Belongs to the peptidase S26 family
GVI77_RS06165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GVI77_RS06180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS06185	COG1737	Transcriptional regulator
GVI77_RS06190	COG0560	Phosphoserine phosphatase
GVI77_RS06195	COG0590	tRNA wobble adenosine to inosine editing
GVI77_RS06210	COG2205	protein histidine kinase activity
GVI77_RS06215	COG3170	Tfp pilus assembly protein FimV
GVI77_RS06220	COG2204	response regulator
GVI77_RS06225	COG0347	Belongs to the P(II) protein family
GVI77_RS06230	COG1017	nitric oxide dioxygenase activity
GVI77_RS06230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GVI77_RS06240	COG1940	carbohydrate kinase activity
GVI77_RS06245	COG0457	Tetratricopeptide repeat
GVI77_RS06250	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS06255	COG1129	ABC transporter
GVI77_RS06260	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS06265	COG1063	alcohol dehydrogenase
GVI77_RS06270	COG2017	converts alpha-aldose to the beta-anomer
GVI77_RS06275	COG2259	Doxx family
GVI77_RS06280	COG2814	Major facilitator Superfamily
GVI77_RS06285	COG3711	transcriptional antiterminator
GVI77_RS06290	COG1073	alpha beta
GVI77_RS06295	COG0483	inositol monophosphate 1-phosphatase activity
GVI77_RS06315	COG0822	iron-sulfur transferase activity
GVI77_RS06335	COG0633	Ferredoxin
GVI77_RS06340	COG2975	iron-sulfur cluster assembly
GVI77_RS06355	COG2897	thiosulfate sulfurtransferase activity
GVI77_RS06360	COG2373	Large extracellular alpha-helical protein
GVI77_RS06365	COG4953	penicillin-binding protein 1C
GVI77_RS06395	COG2976	Protein conserved in bacteria
GVI77_RS06410	COG1645	bacterial-type flagellum-dependent swarming motility
GVI77_RS06435	COG0516	GMP reductase activity
GVI77_RS06435	COG0517	IMP dehydrogenase activity
GVI77_RS06450	COG3133	Outer membrane lipoprotein
GVI77_RS06465	COG2200	EAL domain
GVI77_RS06470	COG0248	Ppx GppA phosphatase
GVI77_RS06475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GVI77_RS06480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GVI77_RS06495	COG2233	PERMEase
GVI77_RS06505	COG1393	Belongs to the ArsC family
GVI77_RS06510	COG4783	chaperone-mediated protein folding
GVI77_RS06515	COG0628	permease
GVI77_RS06520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GVI77_RS06525	COG2716	regulation of RNA biosynthetic process
GVI77_RS06535	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GVI77_RS06545	COG2321	neutral zinc metallopeptidase
GVI77_RS06555	COG0400	carboxylic ester hydrolase activity
GVI77_RS06570	COG1393	Belongs to the ArsC family
GVI77_RS06580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI77_RS06585	COG3850	Histidine kinase
GVI77_RS06590	COG0493	'glutamate synthase
GVI77_RS06590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS06600	COG5342	invasion associated locus B
GVI77_RS06605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GVI77_RS06610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GVI77_RS06615	COG0280	phosphate acetyltransferase
GVI77_RS06615	COG0281	malic enzyme
GVI77_RS06620	COG4810	utilization protein
GVI77_RS06625	COG4917	ethanolamine utilization protein
GVI77_RS06630	COG4766	ethanolamine catabolic process
GVI77_RS06635	COG4812	Cobalamin adenosyltransferase
GVI77_RS06640	COG0280	phosphate acetyltransferase
GVI77_RS06645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GVI77_RS06650	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GVI77_RS06655	COG1012	belongs to the aldehyde dehydrogenase family
GVI77_RS06660	COG4820	ethanolamine utilization protein (EutJ)
GVI77_RS06665	COG1454	alcohol dehydrogenase
GVI77_RS06670	COG3192	ethanolamine utilization protein
GVI77_RS06675	COG4819	ethanolamine utilization protein
GVI77_RS06680	COG4303	Ethanolamine ammonia lyase large subunit
GVI77_RS06690	COG4816	utilization protein
GVI77_RS06695	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GVI77_RS06700	COG2207	Transcriptional regulator
GVI77_RS06710	COG0860	N-Acetylmuramoyl-L-alanine amidase
GVI77_RS06730	COG2837	iron assimilation
GVI77_RS06735	COG1263	PTS System
GVI77_RS06735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS06750	COG4150	thiosulfate binding
GVI77_RS06755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GVI77_RS06760	COG4208	sulfate ABC transporter
GVI77_RS06765	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GVI77_RS06770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GVI77_RS06785	COG2190	(PTS) system
GVI77_RS06790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GVI77_RS06795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS06800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GVI77_RS06820	COG3530	Putative quorum-sensing-regulated virulence factor
GVI77_RS06825	COG0385	Bile acid
GVI77_RS06830	COG0583	DNA-binding transcription factor activity
GVI77_RS06840	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GVI77_RS06845	COG2211	Major facilitator Superfamily
GVI77_RS06855	COG0583	DNA-binding transcription factor activity
GVI77_RS06880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GVI77_RS06885	COG3415	Transposase
GVI77_RS06890	COG3415	Transposase
GVI77_RS06905	COG2200	EAL domain
GVI77_RS06905	COG2199	diguanylate cyclase activity
GVI77_RS06910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GVI77_RS06935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS06940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS06945	COG0006	proline dipeptidase activity
GVI77_RS06950	COG1363	Peptidase, m42
GVI77_RS06955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS06955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GVI77_RS06955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS06960	COG2207	Transcriptional regulator
GVI77_RS06965	COG3279	Response regulator of the LytR AlgR family
GVI77_RS06970	COG3275	phosphorelay sensor kinase activity
GVI77_RS06975	COG0436	Aminotransferase
GVI77_RS06985	COG1560	Kdo2-lipid A biosynthetic process
GVI77_RS07010	COG0028	Belongs to the TPP enzyme family
GVI77_RS07015	COG0679	Auxin Efflux Carrier
GVI77_RS07020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GVI77_RS07025	COG0784	Response regulator, receiver
GVI77_RS07025	COG2198	Histidine kinase
GVI77_RS07025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS07025	COG2205	protein histidine kinase activity
GVI77_RS07030	COG2197	response regulator
GVI77_RS07035	COG1566	PFAM secretion protein HlyD family protein
GVI77_RS07040	COG0477	Major facilitator Superfamily
GVI77_RS07050	COG2610	gluconate transmembrane transporter activity
GVI77_RS07055	COG0583	DNA-binding transcription factor activity
GVI77_RS07065	COG2116	formate transmembrane transporter activity
GVI77_RS07075	COG2067	long-chain fatty acid transport protein
GVI77_RS07080	COG3691	Protein conserved in bacteria
GVI77_RS07095	COG2062	phosphohistidine phosphatase, SixA
GVI77_RS07100	COG3539	Fimbrial protein
GVI77_RS07120	COG3121	Chaperone
GVI77_RS07125	COG3539	Fimbrial protein
GVI77_RS07130	COG3539	Fimbrial protein
GVI77_RS07135	COG3539	Fimbrial protein
GVI77_RS07165	COG0730	response to heat
GVI77_RS07170	COG3101	peptidyl-lysine hydroxylation
GVI77_RS07185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GVI77_RS07190	COG2814	Major facilitator Superfamily
GVI77_RS07205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GVI77_RS07215	COG0586	Pfam SNARE associated Golgi protein
GVI77_RS07225	COG0285	dihydrofolate synthase activity
GVI77_RS07230	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GVI77_RS07235	COG1286	toxin biosynthetic process
GVI77_RS07240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GVI77_RS07245	COG0163	prenyltransferase activity
GVI77_RS07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS07255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS07260	COG4215	(ABC) transporter
GVI77_RS07265	COG4160	amino acid transport
GVI77_RS07270	COG4598	ABC transporter
GVI77_RS07275	COG1090	epimerase
GVI77_RS07280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GVI77_RS07285	COG0625	glutathione transferase activity
GVI77_RS07290	COG0625	glutathione transferase activity
GVI77_RS07295	COG0622	Phosphoesterase
GVI77_RS07300	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GVI77_RS07305	COG1288	antiporter activity
GVI77_RS07310	COG0280	phosphate acetyltransferase
GVI77_RS07310	COG0857	belongs to the CobB CobQ family
GVI77_RS07315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GVI77_RS07330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI77_RS07335	COG0471	metal ion transport
GVI77_RS07335	COG0490	domain, Protein
GVI77_RS07345	COG0436	Aminotransferase
GVI77_RS07350	COG0583	DNA-binding transcription factor activity
GVI77_RS07370	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GVI77_RS07375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GVI77_RS07380	COG1034	ATP synthesis coupled electron transport
GVI77_RS07395	COG0839	Belongs to the complex I subunit 6 family
GVI77_RS07405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GVI77_RS07410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GVI77_RS07425	COG2234	aminopeptidase activity
GVI77_RS07430	COG2304	oxidoreductase activity
GVI77_RS07440	COG2153	protein acetylation
GVI77_RS07445	COG4575	ribosome binding
GVI77_RS07450	COG1169	isochorismate synthase
GVI77_RS07465	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GVI77_RS07475	COG0318	PFAM AMP-dependent synthetase and ligase
GVI77_RS07495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GVI77_RS07540	COG1414	Transcriptional regulator
GVI77_RS07545	COG4948	Mandelate Racemase Muconate Lactonizing
GVI77_RS07550	COG2271	Major facilitator Superfamily
GVI77_RS07555	COG3836	Belongs to the HpcH HpaI aldolase family
GVI77_RS07565	COG5464	transposase or invertase
GVI77_RS07570	COG0247	lactate metabolic process
GVI77_RS07580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GVI77_RS07585	COG2271	Major facilitator Superfamily
GVI77_RS07590	COG0584	glycerophosphoryl diester phosphodiesterase
GVI77_RS07595	COG3642	lipopolysaccharide core region biosynthetic process
GVI77_RS07600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GVI77_RS07605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GVI77_RS07610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GVI77_RS07615	COG3468	outer membrane autotransporter barrel domain protein
GVI77_RS07625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GVI77_RS07630	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
GVI77_RS07635	COG3234	Protein of unknown function (DUF1175)
GVI77_RS07640	COG2373	Large extracellular alpha-helical protein
GVI77_RS07645	COG5445	Predicted secreted protein (DUF2300)
GVI77_RS07650	COG4676	Protein conserved in bacteria
GVI77_RS07655	COG0183	Belongs to the thiolase family
GVI77_RS07660	COG2031	fatty acid transporter
GVI77_RS07665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GVI77_RS07670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GVI77_RS07675	COG2204	response regulator
GVI77_RS07680	COG3852	Histidine kinase
GVI77_RS07685	COG2205	protein histidine kinase activity
GVI77_RS07685	COG0784	Response regulator, receiver
GVI77_RS07690	COG2197	response regulator
GVI77_RS07695	COG0642	Histidine kinase
GVI77_RS07695	COG2198	Histidine kinase
GVI77_RS07705	COG1477	protein flavinylation
GVI77_RS07710	COG2169	Transcriptional regulator
GVI77_RS07710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GVI77_RS07715	COG3145	DNA-N1-methyladenine dioxygenase activity
GVI77_RS07720	COG4615	Cyclic peptide transporter
GVI77_RS07735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS07735	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI77_RS07740	COG3062	negative regulation of establishment of protein localization
GVI77_RS07750	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS07755	COG0348	domain, Protein
GVI77_RS07760	COG3043	anaerobic respiration
GVI77_RS07765	COG3005	denitrification pathway
GVI77_RS07770	COG4133	protoheme IX ABC transporter activity
GVI77_RS07775	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GVI77_RS07780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GVI77_RS07785	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GVI77_RS07795	COG1138	Cytochrome C-type biogenesis protein
GVI77_RS07800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GVI77_RS07805	COG3088	subunit of a heme lyase
GVI77_RS07805	COG4235	cytochrome complex assembly
GVI77_RS07810	COG2197	response regulator
GVI77_RS07825	COG3083	sulfuric ester hydrolase activity
GVI77_RS07845	COG1061	Type III restriction enzyme res subunit
GVI77_RS07850	COG1187	pseudouridine synthase activity
GVI77_RS07855	COG2814	Major facilitator Superfamily
GVI77_RS07865	COG4172	Belongs to the ABC transporter superfamily
GVI77_RS07870	COG4239	(ABC) transporter, permease
GVI77_RS07875	COG4174	ABC transporter (Permease)
GVI77_RS07880	COG4166	transmembrane transport
GVI77_RS07885	COG2200	EAL domain
GVI77_RS07890	COG0791	NLP P60 protein
GVI77_RS07895	COG0671	phosphoesterase, PA-phosphatase related
GVI77_RS07900	COG0523	cobalamin synthesis protein
GVI77_RS07905	COG0246	Mannitol dehydrogenase
GVI77_RS07920	COG2814	Major facilitator Superfamily
GVI77_RS07925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS07925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS07930	COG1105	Belongs to the carbohydrate kinase PfkB family
GVI77_RS07935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS07935	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GVI77_RS07935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS07940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS07945	COG2313	pseudouridylate synthase activity
GVI77_RS07950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GVI77_RS07955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GVI77_RS07965	COG1522	sequence-specific DNA binding
GVI77_RS07965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS07975	COG2855	membrane
GVI77_RS07980	COG0583	DNA-binding transcription factor activity
GVI77_RS07985	COG0833	amino acid
GVI77_RS07990	COG4771	TonB-dependent receptor
GVI77_RS08005	COG2311	Membrane
GVI77_RS08010	COG1609	Transcriptional regulator
GVI77_RS08015	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS08025	COG4211	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS08030	COG0167	dihydroorotate dehydrogenase activity
GVI77_RS08030	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GVI77_RS08035	COG0493	'glutamate synthase
GVI77_RS08045	COG2949	membrane
GVI77_RS08055	COG1346	cytolysis
GVI77_RS08065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GVI77_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS08085	COG0586	Pfam SNARE associated Golgi protein
GVI77_RS08095	COG1686	Belongs to the peptidase S11 family
GVI77_RS08100	COG0277	FAD linked oxidase domain protein
GVI77_RS08105	COG1472	Belongs to the glycosyl hydrolase 3 family
GVI77_RS08110	COG1732	Glycine betaine
GVI77_RS08115	COG1174	glycine betaine transport
GVI77_RS08120	COG1125	glycine betaine transport
GVI77_RS08125	COG1174	glycine betaine transport
GVI77_RS08135	COG0789	Transcriptional regulator
GVI77_RS08140	COG3275	phosphorelay sensor kinase activity
GVI77_RS08145	COG3279	Response regulator of the LytR AlgR family
GVI77_RS08150	COG4807	Protein conserved in bacteria
GVI77_RS08155	COG4808	Protein conserved in bacteria
GVI77_RS08160	COG4715	Zinc finger, swim domain protein
GVI77_RS08170	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GVI77_RS08175	COG0714	Associated with various cellular activities
GVI77_RS08185	COG3831	ATPase activity
GVI77_RS08190	COG3831	ATPase activity
GVI77_RS08195	COG3831	ATPase activity
GVI77_RS08205	COG0489	protein tyrosine kinase activity
GVI77_RS08215	COG3539	Fimbrial protein
GVI77_RS08220	COG3121	Chaperone
GVI77_RS08225	COG3188	usher protein
GVI77_RS08230	COG3539	Fimbrial protein
GVI77_RS08235	COG5455	response to cobalt ion
GVI77_RS08255	COG0351	phosphomethylpyrimidine kinase
GVI77_RS08260	COG3757	hydrolase, family 25
GVI77_RS08265	COG2188	Transcriptional regulator
GVI77_RS08270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS08275	COG1397	ADP-ribosylglycohydrolase
GVI77_RS08280	COG2211	Major facilitator Superfamily
GVI77_RS08285	COG1830	Aldolase
GVI77_RS08300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS08305	COG3414	Phosphotransferase system galactitol-specific IIB component
GVI77_RS08310	COG3775	system Galactitol-specific IIC component
GVI77_RS08315	COG1063	alcohol dehydrogenase
GVI77_RS08335	COG0826	peptidase U32
GVI77_RS08345	COG0745	RESPONSE REGULATOR receiver
GVI77_RS08350	COG2205	protein histidine kinase activity
GVI77_RS08395	COG4245	von Willebrand factor, type A
GVI77_RS08400	COG0631	protein serine/threonine phosphatase activity
GVI77_RS08405	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
GVI77_RS08410	COG0443	Heat shock 70 kDa protein
GVI77_RS08415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GVI77_RS08420	COG3447	MASE1 domain protein
GVI77_RS08420	COG5001	Diguanylate cyclase
GVI77_RS08420	COG5002	protein histidine kinase activity
GVI77_RS08425	COG0572	uridine kinase
GVI77_RS08435	COG2982	Protein involved in outer membrane biogenesis
GVI77_RS08440	COG1253	flavin adenine dinucleotide binding
GVI77_RS08445	COG1596	polysaccharide export
GVI77_RS08450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GVI77_RS08455	COG0489	protein tyrosine kinase activity
GVI77_RS08455	COG3206	protein involved in exopolysaccharide biosynthesis
GVI77_RS08460	COG0463	Glycosyl transferase, family 2
GVI77_RS08465	COG1045	serine acetyltransferase
GVI77_RS08470	COG0438	transferase activity, transferring glycosyl groups
GVI77_RS08480	COG1216	Glycosyl transferase, family 2
GVI77_RS08485	COG0110	maltose O-acetyltransferase activity
GVI77_RS08490	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GVI77_RS08495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GVI77_RS08500	COG1051	belongs to the nudix hydrolase family
GVI77_RS08505	COG0297	glycogen (starch) synthase activity
GVI77_RS08510	COG0662	Cupin 2, conserved barrel domain protein
GVI77_RS08510	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GVI77_RS08515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GVI77_RS08520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GVI77_RS08525	COG2244	polysaccharide biosynthetic process
GVI77_RS08530	COG2327	Polysaccharide pyruvyl transferase
GVI77_RS08535	COG0438	transferase activity, transferring glycosyl groups
GVI77_RS08545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GVI77_RS08550	COG1088	dTDP-glucose 4,6-dehydratase activity
GVI77_RS08560	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GVI77_RS08565	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GVI77_RS08570	COG2244	polysaccharide biosynthetic process
GVI77_RS08575	COG0562	UDP-galactopyranose mutase
GVI77_RS08585	COG0438	transferase activity, transferring glycosyl groups
GVI77_RS08590	COG0110	maltose O-acetyltransferase activity
GVI77_RS08595	COG0438	transferase activity, transferring glycosyl groups
GVI77_RS08605	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GVI77_RS08610	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GVI77_RS08615	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GVI77_RS08620	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GVI77_RS08620	COG0140	phosphoribosyl-ATP diphosphatase activity
GVI77_RS08635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GVI77_RS08640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GVI77_RS08640	COG0131	Imidazoleglycerol-phosphate dehydratase
GVI77_RS08650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GVI77_RS08665	COG2161	toxin-antitoxin pair type II binding
GVI77_RS08670	COG4115	mRNA cleavage
GVI77_RS08675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GVI77_RS08680	COG0583	DNA-binding transcription factor activity
GVI77_RS08690	COG0531	amino acid
GVI77_RS08695	COG2925	Exonuclease
GVI77_RS08700	COG1686	Belongs to the peptidase S11 family
GVI77_RS08710	COG1289	transmembrane transporter activity
GVI77_RS08730	COG4584	PFAM Integrase catalytic
GVI77_RS08735	COG1484	DNA-dependent DNA replication
GVI77_RS08765	COG2003	Belongs to the UPF0758 family
GVI77_RS08820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS08825	COG1120	ATPase activity
GVI77_RS08880	COG3547	Transposase (IS116 IS110 IS902 family)
GVI77_RS08885	COG4372	Transposase
GVI77_RS08890	COG3436	PFAM IS66 Orf2 family protein
GVI77_RS08930	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GVI77_RS08945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS08965	COG1215	transferase activity, transferring glycosyl groups
GVI77_RS08970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GVI77_RS08975	COG3969	phosphoadenosine phosphosulfate
GVI77_RS08980	COG1475	DNA binding
GVI77_RS08985	COG4771	TonB-dependent receptor
GVI77_RS08990	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GVI77_RS09005	COG1376	ErfK ybiS ycfS ynhG family protein
GVI77_RS09015	COG0583	DNA-binding transcription factor activity
GVI77_RS09020	COG0583	DNA-binding transcription factor activity
GVI77_RS09030	COG0534	Mate efflux family protein
GVI77_RS09040	COG0217	transcriptional regulatory protein
GVI77_RS09045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GVI77_RS09050	COG0477	Major facilitator Superfamily
GVI77_RS09070	COG1388	LysM domain
GVI77_RS09070	COG1470	cell adhesion involved in biofilm formation
GVI77_RS09080	COG1388	LysM domain
GVI77_RS09080	COG4932	domain protein
GVI77_RS09080	COG2373	Large extracellular alpha-helical protein
GVI77_RS09085	COG4771	TonB-dependent receptor
GVI77_RS09090	COG1021	2,3-dihydroxybenzoate-AMP ligase
GVI77_RS09110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GVI77_RS09110	COG2226	methyltransferase
GVI77_RS09110	COG3433	isochorismatase activity
GVI77_RS09125	COG1132	(ABC) transporter
GVI77_RS09130	COG2814	Major facilitator Superfamily
GVI77_RS09135	COG1169	isochorismate synthase
GVI77_RS09140	COG0582	viral genome integration into host DNA
GVI77_RS09160	COG3443	Belongs to the bacterial solute-binding protein 9 family
GVI77_RS09175	COG2351	hydroxyisourate hydrolase activity
GVI77_RS09180	COG0745	RESPONSE REGULATOR receiver
GVI77_RS09185	COG2205	protein histidine kinase activity
GVI77_RS09195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GVI77_RS09205	COG1418	mRNA catabolic process
GVI77_RS09210	COG0270	DNA (cytosine-5-)-methyltransferase activity
GVI77_RS09215	COG3727	T/G mismatch-specific endonuclease activity
GVI77_RS09220	COG0697	spore germination
GVI77_RS09225	COG2354	Protein conserved in bacteria
GVI77_RS09230	COG5475	Uncharacterized small protein (DUF2158)
GVI77_RS09235	COG3706	GGDEF domain
GVI77_RS09255	COG2197	response regulator
GVI77_RS09260	COG1684	flagellar biosynthetic protein fliR
GVI77_RS09265	COG1987	bacterial-type flagellum assembly
GVI77_RS09270	COG1338	Plays a role in the flagellum-specific transport system
GVI77_RS09275	COG3190	flagellar
GVI77_RS09280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GVI77_RS09285	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GVI77_RS09290	COG1580	Controls the rotational direction of flagella during chemotaxis
GVI77_RS09295	COG3144	bacterial-type flagellum assembly
GVI77_RS09300	COG2882	bacterial-type flagellum organization
GVI77_RS09305	COG1157	protein secretion by the type III secretion system
GVI77_RS09310	COG1317	bacterial-type flagellum organization
GVI77_RS09315	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GVI77_RS09320	COG1766	The M ring may be actively involved in energy transduction
GVI77_RS09330	COG2076	Multidrug Resistance protein
GVI77_RS09335	COG1881	PFAM PEBP family protein
GVI77_RS09340	COG2207	Transcriptional regulator
GVI77_RS09350	COG0675	Transposase, IS605 OrfB family
GVI77_RS09360	COG0425	Belongs to the sulfur carrier protein TusA family
GVI77_RS09365	COG2391	methyltransferase activity
GVI77_RS09375	COG0366	Alpha amylase catalytic
GVI77_RS09385	COG1516	flagellar protein fliS
GVI77_RS09390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GVI77_RS09400	COG1191	sigma factor activity
GVI77_RS09410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS09420	COG0765	amino acid transport
GVI77_RS09425	COG1126	abc transporter atp-binding protein
GVI77_RS09430	COG2197	response regulator
GVI77_RS09445	COG2197	response regulator
GVI77_RS09475	COG3012	SEC-C Motif Domain Protein
GVI77_RS09475	COG3318	Belongs to the UPF0149 family
GVI77_RS09480	COG0814	amino acid
GVI77_RS09490	COG1528	Iron-storage protein
GVI77_RS09510	COG1528	Iron-storage protein
GVI77_RS09515	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS09525	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS09530	COG1877	trehalose-phosphatase activity
GVI77_RS09540	COG0589	response to stress
GVI77_RS09555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GVI77_RS09560	COG1360	Flagellar Motor Protein
GVI77_RS09565	COG2198	Histidine kinase
GVI77_RS09565	COG0643	Histidine kinase
GVI77_RS09570	COG0835	chemotaxis
GVI77_RS09575	COG0840	transmembrane signaling receptor activity
GVI77_RS09585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GVI77_RS09595	COG0745	RESPONSE REGULATOR receiver
GVI77_RS09600	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GVI77_RS09605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GVI77_RS09610	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GVI77_RS09625	COG3102	Protein conserved in bacteria
GVI77_RS09635	COG3005	denitrification pathway
GVI77_RS09640	COG0243	molybdopterin cofactor binding
GVI77_RS09655	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GVI77_RS09660	COG1801	Protein of unknown function DUF72
GVI77_RS09665	COG1335	isochorismatase
GVI77_RS09675	COG0494	nUDIX hydrolase
GVI77_RS09680	COG0217	transcriptional regulatory protein
GVI77_RS09715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GVI77_RS09725	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GVI77_RS09730	COG0739	heme binding
GVI77_RS09735	COG1560	Kdo2-lipid A biosynthetic process
GVI77_RS09740	COG0469	pyruvate kinase activity
GVI77_RS09745	COG1737	Transcriptional regulator
GVI77_RS09750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GVI77_RS09755	COG0129	dihydroxy-acid dehydratase activity
GVI77_RS09760	COG0800	Aldolase
GVI77_RS09770	COG3141	response to X-ray
GVI77_RS09780	COG2979	Protein of unknown function (DUF533)
GVI77_RS09785	COG1770	oligopeptidase
GVI77_RS09790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GVI77_RS09795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GVI77_RS09805	COG2372	response to copper ion
GVI77_RS09810	COG1276	copper resistance
GVI77_RS09820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GVI77_RS09840	COG3008	intermembrane lipid transfer
GVI77_RS09845	COG2995	paraquat-inducible protein a
GVI77_RS09850	COG1956	GAF domain-containing protein
GVI77_RS09860	COG0793	Belongs to the peptidase S41A family
GVI77_RS09870	COG2814	Major facilitator Superfamily
GVI77_RS09875	COG1414	Transcriptional regulator
GVI77_RS09905	COG2226	methyltransferase
GVI77_RS09920	COG3716	PTS system mannose fructose sorbose family IID component
GVI77_RS09925	COG3715	PTS system
GVI77_RS09930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS09930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS09935	COG1253	flavin adenine dinucleotide binding
GVI77_RS09940	COG2200	EAL domain
GVI77_RS09945	COG1760	l-serine dehydratase
GVI77_RS09955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GVI77_RS09970	COG0251	oxidation-reduction process
GVI77_RS09975	COG1199	ATP-dependent helicase activity
GVI77_RS09980	COG1214	PFAM Peptidase M22, glycoprotease
GVI77_RS09985	COG3065	identical protein binding
GVI77_RS09990	COG0318	PFAM AMP-dependent synthetase and ligase
GVI77_RS09995	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GVI77_RS10010	COG3615	Tellurite resistance protein tehB
GVI77_RS10020	COG2261	transglycosylase associated protein
GVI77_RS10035	COG2203	Gaf domain
GVI77_RS10035	COG2199	diguanylate cyclase activity
GVI77_RS10040	COG3042	response to heat
GVI77_RS10045	COG3189	MarR family transcriptional regulator
GVI77_RS10050	COG2807	transmembrane transport
GVI77_RS10055	COG2207	Transcriptional regulator
GVI77_RS10070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GVI77_RS10075	COG2199	diguanylate cyclase activity
GVI77_RS10080	COG2199	diguanylate cyclase activity
GVI77_RS10090	COG2766	serine protein kinase
GVI77_RS10095	COG3713	MltA-interacting MipA family protein
GVI77_RS10100	COG0656	L-ascorbic acid biosynthetic process
GVI77_RS10105	COG0676	glucose-6-phosphate 1-epimerase activity
GVI77_RS10110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GVI77_RS10120	COG3139	Protein of unknown function (DUF1315)
GVI77_RS10125	COG1063	alcohol dehydrogenase
GVI77_RS10130	COG2271	Major facilitator Superfamily
GVI77_RS10135	COG1063	alcohol dehydrogenase
GVI77_RS10140	COG0191	fructose-bisphosphate aldolase activity
GVI77_RS10145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS10150	COG0667	Aldo Keto reductase
GVI77_RS10155	COG1349	DNA-binding transcription factor activity
GVI77_RS10160	COG2814	Major facilitator Superfamily
GVI77_RS10165	COG1335	isochorismatase
GVI77_RS10170	COG0252	asparaginase activity
GVI77_RS10180	COG0616	signal peptide processing
GVI77_RS10185	COG0778	Nitroreductase
GVI77_RS10190	COG0709	Synthesizes selenophosphate from selenide and ATP
GVI77_RS10195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GVI77_RS10200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GVI77_RS10210	COG0494	nUDIX hydrolase
GVI77_RS10215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GVI77_RS10220	COG2897	thiosulfate sulfurtransferase activity
GVI77_RS10225	COG4136	ATPase activity
GVI77_RS10230	COG4135	transport system, permease component
GVI77_RS10235	COG4134	Bacterial extracellular solute-binding protein
GVI77_RS10240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GVI77_RS10245	COG0398	Pfam SNARE associated Golgi protein
GVI77_RS10255	COG0398	Pfam SNARE associated Golgi protein
GVI77_RS10260	COG0708	Exodeoxyribonuclease III
GVI77_RS10290	COG3678	ATP-independent chaperone mediated protein folding
GVI77_RS10300	COG0322	excinuclease ABC activity
GVI77_RS10310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI77_RS10315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI77_RS10320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI77_RS10325	COG1447	Phosphotransferase system cellobiose-specific component IIA
GVI77_RS10330	COG2169	Transcriptional regulator
GVI77_RS10330	COG1917	Cupin 2, conserved barrel domain protein
GVI77_RS10335	COG1486	melibiose metabolic process
GVI77_RS10340	COG3394	polysaccharide catabolic process
GVI77_RS10345	COG0753	catalase activity
GVI77_RS10355	COG1823	symporter activity
GVI77_RS10360	COG1988	membrane-bound metal-dependent
GVI77_RS10365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI77_RS10375	COG3001	Fructosamine kinase
GVI77_RS10385	COG1105	Belongs to the carbohydrate kinase PfkB family
GVI77_RS10390	COG3137	Salt-induced outer membrane protein
GVI77_RS10450	COG0386	Belongs to the glutathione peroxidase family
GVI77_RS10460	COG0791	NLP P60 protein
GVI77_RS10465	COG2200	EAL domain
GVI77_RS10475	COG4256	Hemin uptake protein
GVI77_RS10480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GVI77_RS10490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GVI77_RS10490	COG0574	Belongs to the PEP-utilizing enzyme family
GVI77_RS10495	COG0318	PFAM AMP-dependent synthetase and ligase
GVI77_RS10500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GVI77_RS10505	COG0644	oxidoreductase
GVI77_RS10510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GVI77_RS10515	COG2086	electron transfer activity
GVI77_RS10520	COG2207	Transcriptional regulator
GVI77_RS10520	COG1917	Cupin 2, conserved barrel domain protein
GVI77_RS10525	COG1960	acyl-CoA dehydrogenase activity
GVI77_RS10530	COG4670	ketone body catabolic process
GVI77_RS10545	COG2271	Major facilitator Superfamily
GVI77_RS10550	COG0738	Major facilitator superfamily
GVI77_RS10565	COG0628	permease
GVI77_RS10570	COG0247	lactate metabolic process
GVI77_RS10570	COG0277	FAD linked oxidase domain protein
GVI77_RS10575	COG2050	protein possibly involved in aromatic compounds catabolism
GVI77_RS10585	COG0316	Belongs to the HesB IscA family
GVI77_RS10590	COG0719	Fe-S assembly protein
GVI77_RS10595	COG0396	ATPase activity
GVI77_RS10600	COG0719	Fe-S assembly protein
GVI77_RS10615	COG1376	ErfK ybiS ycfS ynhG family protein
GVI77_RS10620	COG4238	major outer membrane lipoprotein
GVI77_RS10625	COG0469	pyruvate kinase activity
GVI77_RS10635	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS10640	COG2414	aldehyde ferredoxin oxidoreductase
GVI77_RS10650	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS10655	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GVI77_RS10665	COG4529	Protein conserved in bacteria
GVI77_RS10685	COG3468	outer membrane autotransporter barrel domain protein
GVI77_RS10695	COG0307	riboflavin synthase, alpha
GVI77_RS10700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GVI77_RS10705	COG2814	Major facilitator Superfamily
GVI77_RS10710	COG0583	DNA-binding transcription factor activity
GVI77_RS10725	COG2814	Major facilitator Superfamily
GVI77_RS10730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GVI77_RS10735	COG0791	NLP P60 protein
GVI77_RS10740	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GVI77_RS10745	COG1201	RNA secondary structure unwinding
GVI77_RS10755	COG0346	lactoylglutathione lyase activity
GVI77_RS10760	COG1902	pentaerythritol trinitrate reductase activity
GVI77_RS10765	COG1309	transcriptional regulator
GVI77_RS10770	COG3313	Fe-S protein
GVI77_RS10775	COG4989	oxidoreductase activity
GVI77_RS10780	COG2032	superoxide dismutase activity
GVI77_RS10785	COG1289	transmembrane transporter activity
GVI77_RS10790	COG1566	PFAM secretion protein HlyD family protein
GVI77_RS10805	COG3133	Outer membrane lipoprotein
GVI77_RS10815	COG3895	Periplasmic Protein
GVI77_RS10835	COG0625	glutathione transferase activity
GVI77_RS10840	COG3104	oligopeptide transport
GVI77_RS10845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GVI77_RS10855	COG4659	FMN binding
GVI77_RS10895	COG0673	inositol 2-dehydrogenase activity
GVI77_RS10905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GVI77_RS10910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS10910	COG1263	PTS System
GVI77_RS10915	COG1609	Transcriptional regulator
GVI77_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS10925	COG1309	transcriptional regulator
GVI77_RS10930	COG3250	beta-galactosidase activity
GVI77_RS10945	COG5339	Protein conserved in bacteria
GVI77_RS10950	COG1482	cell wall glycoprotein biosynthetic process
GVI77_RS10955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI77_RS10955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI77_RS10960	COG0114	fumarate hydratase activity
GVI77_RS10970	COG2205	protein histidine kinase activity
GVI77_RS10975	COG0745	RESPONSE REGULATOR receiver
GVI77_RS10980	COG3136	membrane protein required for alginate biosynthesis
GVI77_RS10985	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS10990	COG0531	amino acid
GVI77_RS11000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GVI77_RS11005	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GVI77_RS11010	COG0628	permease
GVI77_RS11025	COG3591	Belongs to the peptidase S1B family
GVI77_RS11040	COG2814	Major facilitator Superfamily
GVI77_RS11045	COG0583	DNA-binding transcription factor activity
GVI77_RS11050	COG1940	carbohydrate kinase activity
GVI77_RS11055	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GVI77_RS11065	COG3381	protein complex oligomerization
GVI77_RS11070	COG3302	dmso reductase anchor subunit
GVI77_RS11075	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS11085	COG0243	molybdopterin cofactor binding
GVI77_RS11100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI77_RS11115	COG4948	Mandelate Racemase Muconate Lactonizing
GVI77_RS11125	COG0477	Major facilitator Superfamily
GVI77_RS11130	COG0246	Mannitol dehydrogenase
GVI77_RS11140	COG1802	Transcriptional regulator
GVI77_RS11145	COG4221	oxidoreductase activity
GVI77_RS11150	COG0339	signal peptide processing
GVI77_RS11160	COG3706	GGDEF domain
GVI77_RS11170	COG2814	Major facilitator Superfamily
GVI77_RS11175	COG0697	spore germination
GVI77_RS11185	COG4977	sequence-specific DNA binding
GVI77_RS11190	COG1846	Transcriptional regulator
GVI77_RS11210	COG0583	DNA-binding transcription factor activity
GVI77_RS11215	COG1012	belongs to the aldehyde dehydrogenase family
GVI77_RS11220	COG2066	Belongs to the glutaminase family
GVI77_RS11230	COG2199	diguanylate cyclase activity
GVI77_RS11240	COG3781	membrane
GVI77_RS11250	COG1396	sequence-specific DNA binding
GVI77_RS11255	COG3550	peptidyl-serine autophosphorylation
GVI77_RS11260	COG3539	Fimbrial protein
GVI77_RS11270	COG3188	usher protein
GVI77_RS11275	COG3539	Fimbrial protein
GVI77_RS11280	COG3539	Fimbrial protein
GVI77_RS11285	COG3539	Fimbrial protein
GVI77_RS11290	COG0243	molybdopterin cofactor binding
GVI77_RS11300	COG2207	Transcriptional regulator
GVI77_RS11305	COG3119	arylsulfatase activity
GVI77_RS11310	COG0641	radical SAM
GVI77_RS11320	COG0076	glutamate decarboxylase activity
GVI77_RS11325	COG0531	amino acid
GVI77_RS11330	COG1649	PFAM Uncharacterised BCR, COG1649
GVI77_RS11340	COG2202	Pas domain
GVI77_RS11340	COG2200	EAL domain
GVI77_RS11340	COG2199	diguanylate cyclase activity
GVI77_RS11345	COG1764	response to oxidative stress
GVI77_RS11365	COG1064	alcohol dehydrogenase
GVI77_RS11375	COG3093	addiction module antidote protein HigA
GVI77_RS11380	COG2864	formate dehydrogenase
GVI77_RS11385	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS11395	COG0697	spore germination
GVI77_RS11400	COG2223	nitrite transmembrane transporter activity
GVI77_RS11405	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GVI77_RS11410	COG1140	nitrate reductase beta subunit
GVI77_RS11415	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GVI77_RS11420	COG2181	nitrate reductase activity
GVI77_RS11425	COG0384	phenazine biosynthesis protein PhzF
GVI77_RS11430	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GVI77_RS11435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GVI77_RS11440	COG5433	transposase activity
GVI77_RS11445	COG1113	amino acid transport
GVI77_RS11455	COG4772	TonB-dependent receptor
GVI77_RS11465	COG1247	-acetyltransferase
GVI77_RS11470	COG3238	Protein conserved in bacteria
GVI77_RS11495	COG1177	transmembrane transport
GVI77_RS11500	COG1176	ABC-type spermidine putrescine transport system, permease component I
GVI77_RS11505	COG3842	ATPase activity
GVI77_RS11510	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GVI77_RS11515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GVI77_RS11530	COG0826	peptidase U32
GVI77_RS11535	COG1396	sequence-specific DNA binding
GVI77_RS11540	COG3135	benzoate transporter
GVI77_RS11550	COG0500	methyltransferase
GVI77_RS11555	COG1275	C4-dicarboxylate transporter malic acid transport protein
GVI77_RS11560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GVI77_RS11565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI77_RS11570	COG2841	Protein conserved in bacteria
GVI77_RS11580	COG5383	Protein conserved in bacteria
GVI77_RS11585	COG0583	DNA-binding transcription factor activity
GVI77_RS11605	COG3038	cytochrome b561
GVI77_RS11610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GVI77_RS11615	COG1012	belongs to the aldehyde dehydrogenase family
GVI77_RS11620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GVI77_RS11625	COG1643	Atp-dependent helicase
GVI77_RS11635	COG0667	Aldo Keto reductase
GVI77_RS11655	COG3784	Protein of unknown function (DUF1318)
GVI77_RS11665	COG2911	Protein conserved in bacteria
GVI77_RS11670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GVI77_RS11675	COG3187	Heat shock protein
GVI77_RS11680	COG3042	response to heat
GVI77_RS11685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GVI77_RS11685	COG0674	pyruvate-flavodoxin oxidoreductase activity
GVI77_RS11685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GVI77_RS11685	COG1013	pyruvate-flavodoxin oxidoreductase activity
GVI77_RS11690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GVI77_RS11695	COG0589	response to stress
GVI77_RS11720	COG0513	Belongs to the DEAD box helicase family
GVI77_RS11730	COG3706	GGDEF domain
GVI77_RS11735	COG2840	Smr protein MutS2
GVI77_RS11750	COG2207	Transcriptional regulator
GVI77_RS11760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GVI77_RS11765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GVI77_RS11770	COG0589	response to stress
GVI77_RS11775	COG3182	Iron-regulated membrane protein
GVI77_RS11780	COG0668	transmembrane transport
GVI77_RS11785	COG4166	transmembrane transport
GVI77_RS11790	COG0583	DNA-binding transcription factor activity
GVI77_RS11795	COG1073	alpha beta
GVI77_RS11800	COG0702	epimerase
GVI77_RS11805	COG2866	Carboxypeptidase
GVI77_RS11810	COG4948	Mandelate Racemase Muconate Lactonizing
GVI77_RS11815	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GVI77_RS11820	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GVI77_RS11830	COG3106	COG3106 Predicted ATPase
GVI77_RS11835	COG1609	Transcriptional regulator
GVI77_RS11850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI77_RS11855	COG1554	hydrolase, family 65, central catalytic
GVI77_RS11860	COG0673	inositol 2-dehydrogenase activity
GVI77_RS11865	COG1082	Xylose isomerase domain protein TIM barrel
GVI77_RS11870	COG1063	alcohol dehydrogenase
GVI77_RS11875	COG0395	ABC-type sugar transport system, permease component
GVI77_RS11880	COG1175	transmembrane transport
GVI77_RS11885	COG1653	transport
GVI77_RS11890	COG0366	Alpha amylase catalytic
GVI77_RS11895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GVI77_RS11905	COG1983	PspC domain protein
GVI77_RS11915	COG1842	Phage shock protein A
GVI77_RS11920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GVI77_RS11935	COG4166	transmembrane transport
GVI77_RS11940	COG4168	peptide transport system, permease
GVI77_RS11945	COG4171	peptide transport system, permease
GVI77_RS11950	COG4172	Belongs to the ABC transporter superfamily
GVI77_RS11955	COG4172	Belongs to the ABC transporter superfamily
GVI77_RS11960	COG2814	Major facilitator Superfamily
GVI77_RS11970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI77_RS11975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS11985	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GVI77_RS11990	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GVI77_RS11990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GVI77_RS12005	COG5001	Diguanylate cyclase
GVI77_RS12015	COG1349	DNA-binding transcription factor activity
GVI77_RS12025	COG0023	Translation Initiation Factor
GVI77_RS12035	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GVI77_RS12040	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GVI77_RS12045	COG0671	phosphoesterase, PA-phosphatase related
GVI77_RS12055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GVI77_RS12075	COG0583	DNA-binding transcription factor activity
GVI77_RS12080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GVI77_RS12090	COG0616	signal peptide processing
GVI77_RS12095	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS12100	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GVI77_RS12115	COG1187	pseudouridine synthase activity
GVI77_RS12120	COG4907	membrane protein (DUF2207)
GVI77_RS12125	COG0009	L-threonylcarbamoyladenylate synthase
GVI77_RS12130	COG0613	PHP domain protein
GVI77_RS12140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GVI77_RS12145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GVI77_RS12145	COG0512	Glutamine amidotransferase of anthranilate synthase
GVI77_RS12150	COG0134	indole-3-glycerol-phosphate synthase activity
GVI77_RS12150	COG0135	phosphoribosylanthranilate isomerase activity
GVI77_RS12165	COG3047	cAMP biosynthetic process
GVI77_RS12185	COG1607	acyl-coa hydrolase
GVI77_RS12195	COG2350	Protein conserved in bacteria
GVI77_RS12200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GVI77_RS12220	COG4608	Belongs to the ABC transporter superfamily
GVI77_RS12225	COG0444	Belongs to the ABC transporter superfamily
GVI77_RS12230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GVI77_RS12235	COG0601	transmembrane transport
GVI77_RS12240	COG4166	transmembrane transport
GVI77_RS12250	COG2095	MarC family integral membrane protein
GVI77_RS12255	COG1012	belongs to the aldehyde dehydrogenase family
GVI77_RS12255	COG1454	alcohol dehydrogenase
GVI77_RS12265	COG1435	thymidine kinase activity
GVI77_RS12275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GVI77_RS12280	COG0745	RESPONSE REGULATOR receiver
GVI77_RS12285	COG1752	Esterase of the alpha-beta hydrolase superfamily
GVI77_RS12295	COG0788	formyltetrahydrofolate deformylase activity
GVI77_RS12335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GVI77_RS12340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GVI77_RS12345	COG2181	nitrate reductase activity
GVI77_RS12350	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GVI77_RS12355	COG1140	nitrate reductase beta subunit
GVI77_RS12360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GVI77_RS12365	COG2223	nitrite transmembrane transporter activity
GVI77_RS12370	COG3850	Histidine kinase
GVI77_RS12375	COG2197	response regulator
GVI77_RS12380	COG4932	domain protein
GVI77_RS12385	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GVI77_RS12390	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GVI77_RS12395	COG4572	Cation transport regulator
GVI77_RS12400	COG0387	Pfam Sodium calcium exchanger
GVI77_RS12415	COG2912	Transglutaminase-like superfamily
GVI77_RS12420	COG3094	Invasion gene expression up-regulator, SirB
GVI77_RS12425	COG2890	protein-(glutamine-N5) methyltransferase activity
GVI77_RS12450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GVI77_RS12455	COG0659	secondary active sulfate transmembrane transporter activity
GVI77_RS12470	COG0012	GTP binding
GVI77_RS12475	COG0582	viral genome integration into host DNA
GVI77_RS12485	COG2801	Transposase and inactivated derivatives
GVI77_RS12545	COG4974	Belongs to the 'phage' integrase family
GVI77_RS12550	COG2003	Belongs to the UPF0758 family
GVI77_RS12570	COG3423	Transcriptional regulator
GVI77_RS12615	COG3284	Transcriptional regulator
GVI77_RS12620	COG2376	Dihydroxyacetone kinase
GVI77_RS12625	COG1461	Dihydroxyacetone kinase
GVI77_RS12630	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GVI77_RS12630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GVI77_RS12630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS12640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GVI77_RS12645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS12650	COG1120	ATPase activity
GVI77_RS12655	COG0500	methyltransferase
GVI77_RS12660	COG0157	Belongs to the NadC ModD family
GVI77_RS12675	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GVI77_RS12685	COG1619	proteins homologs of microcin C7 resistance protein MccF
GVI77_RS12695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GVI77_RS12705	COG2719	SpoVR family
GVI77_RS12715	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GVI77_RS12725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GVI77_RS12730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GVI77_RS12745	COG0179	Fumarylacetoacetate (FAA) hydrolase
GVI77_RS12770	COG2894	cell division
GVI77_RS12850	COG2200	EAL domain
GVI77_RS12855	COG0789	Transcriptional regulator
GVI77_RS12860	COG5562	phage envelope protein
GVI77_RS12870	COG0538	isocitrate dehydrogenase activity
GVI77_RS12880	COG1121	(ABC) transporter
GVI77_RS12885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GVI77_RS12890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GVI77_RS12905	COG4372	Transposase
GVI77_RS12910	COG3436	PFAM IS66 Orf2 family protein
GVI77_RS12920	COG5301	cellulose 1,4-beta-cellobiosidase activity
GVI77_RS12950	COG1196	nuclear chromosome segregation
GVI77_RS13020	COG4220	transposase activity
GVI77_RS13040	COG3772	lysozyme
GVI77_RS13095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GVI77_RS13105	COG2076	Multidrug Resistance protein
GVI77_RS13200	COG0582	viral genome integration into host DNA
GVI77_RS13205	COG0538	isocitrate dehydrogenase activity
GVI77_RS13210	COG1187	pseudouridine synthase activity
GVI77_RS13230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GVI77_RS13240	COG2205	protein histidine kinase activity
GVI77_RS13245	COG2850	peptidyl-arginine hydroxylation
GVI77_RS13255	COG3842	ATPase activity
GVI77_RS13265	COG1177	transmembrane transport
GVI77_RS13270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GVI77_RS13280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GVI77_RS13285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GVI77_RS13295	COG4591	ABC-type transport system involved in lipoprotein release permease component
GVI77_RS13305	COG4591	ABC-type transport system involved in lipoprotein release permease component
GVI77_RS13310	COG4763	Acyl-transferase
GVI77_RS13315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GVI77_RS13320	COG1376	ErfK ybiS ycfS ynhG family protein
GVI77_RS13320	COG1388	LysM domain
GVI77_RS13330	COG1309	transcriptional regulator
GVI77_RS13335	COG3134	Outer membrane lipoprotein
GVI77_RS13340	COG1252	NADH dehydrogenase
GVI77_RS13355	COG0510	thiamine kinase activity
GVI77_RS13360	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GVI77_RS13365	COG5633	Lipoprotein
GVI77_RS13370	COG0537	adenosine 5'-monophosphoramidase activity
GVI77_RS13375	COG4773	Receptor
GVI77_RS13380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS13380	COG1263	PTS System
GVI77_RS13385	COG0084	hydrolase, TatD family'
GVI77_RS13390	COG0470	DNA polymerase III
GVI77_RS13400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GVI77_RS13405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GVI77_RS13410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GVI77_RS13420	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS13425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GVI77_RS13445	COG1399	metal-binding, possibly nucleic acid-binding protein
GVI77_RS13450	COG0424	maF-like protein
GVI77_RS13455	COG0564	pseudouridine synthase activity
GVI77_RS13460	COG1530	ribonuclease E activity
GVI77_RS13465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GVI77_RS13470	COG1256	bacterial-type flagellum assembly
GVI77_RS13475	COG3951	Flagellar rod assembly protein muramidase FlgJ
GVI77_RS13475	COG1705	Flagellar rod assembly protein muramidase FlgJ
GVI77_RS13490	COG4786	Flagellar basal body rod
GVI77_RS13495	COG4787	bacterial-type flagellum-dependent cell motility
GVI77_RS13500	COG1749	Flagellar hook protein flgE
GVI77_RS13505	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GVI77_RS13510	COG1558	bacterial-type flagellum-dependent cell motility
GVI77_RS13515	COG1815	bacterial-type flagellum-dependent cell motility
GVI77_RS13520	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GVI77_RS13525	COG2747	anti-sigma28 factor FlgM
GVI77_RS13530	COG3418	PFAM FlgN family protein
GVI77_RS13535	COG0728	peptidoglycan biosynthetic process
GVI77_RS13540	COG0673	inositol 2-dehydrogenase activity
GVI77_RS13550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI77_RS13560	COG2999	glutathione oxidoreductase activity
GVI77_RS13595	COG3038	cytochrome b561
GVI77_RS13600	COG2353	YceI-like domain
GVI77_RS13610	COG1560	Kdo2-lipid A biosynthetic process
GVI77_RS13625	COG5645	(Lipo)protein
GVI77_RS13630	COG2943	transferase activity, transferring hexosyl groups
GVI77_RS13645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GVI77_RS13650	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GVI77_RS13675	COG2197	response regulator
GVI77_RS13690	COG1462	curli production assembly transport component CsgG
GVI77_RS13700	COG3381	protein complex oligomerization
GVI77_RS13720	COG3706	GGDEF domain
GVI77_RS13725	COG0457	Tetratricopeptide repeat
GVI77_RS13730	COG1649	PFAM Uncharacterised BCR, COG1649
GVI77_RS13730	COG0726	polysaccharide deacetylase
GVI77_RS13735	COG1215	transferase activity, transferring glycosyl groups
GVI77_RS13740	COG3658	cytochrome
GVI77_RS13745	COG1702	phosphate starvation-inducible protein PhoH
GVI77_RS13765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GVI77_RS13775	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GVI77_RS13775	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GVI77_RS13775	COG0506	proline dehydrogenase activity
GVI77_RS13780	COG1309	transcriptional regulator
GVI77_RS13815	COG2233	PERMEase
GVI77_RS13820	COG3729	General stress protein
GVI77_RS13855	COG0243	molybdopterin cofactor binding
GVI77_RS13860	COG3005	denitrification pathway
GVI77_RS13865	COG0745	RESPONSE REGULATOR receiver
GVI77_RS13870	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS13875	COG0784	Response regulator, receiver
GVI77_RS13875	COG2198	Histidine kinase
GVI77_RS13875	COG2205	protein histidine kinase activity
GVI77_RS13880	COG0348	domain, Protein
GVI77_RS13900	COG1278	Cold shock
GVI77_RS13905	COG1278	Cold shock
GVI77_RS13920	COG1294	oxidase, subunit
GVI77_RS13925	COG1271	oxidase subunit
GVI77_RS13930	COG1773	rubredoxin
GVI77_RS13935	COG1999	signal sequence binding
GVI77_RS13940	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GVI77_RS13945	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
GVI77_RS13950	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GVI77_RS13955	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GVI77_RS13965	COG0670	Belongs to the BI1 family
GVI77_RS13970	COG2920	part of a sulfur-relay system
GVI77_RS13975	COG1254	Belongs to the acylphosphatase family
GVI77_RS13990	COG1832	CoA-binding protein
GVI77_RS14005	COG0210	DNA helicase
GVI77_RS14010	COG3304	Inner membrane component domain
GVI77_RS14015	COG1289	transmembrane transporter activity
GVI77_RS14020	COG3070	regulator of competence-specific genes
GVI77_RS14040	COG1067	ATP-dependent peptidase activity
GVI77_RS14050	COG3130	regulation of translation
GVI77_RS14055	COG3009	Protein conserved in bacteria
GVI77_RS14060	COG3008	intermembrane lipid transfer
GVI77_RS14060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GVI77_RS14065	COG2995	paraquat-inducible protein a
GVI77_RS14070	COG0488	(ABC) transporter
GVI77_RS14080	COG3217	Mosc domain protein beta barrel domain protein
GVI77_RS14080	COG0633	Ferredoxin
GVI77_RS14095	COG0431	NADPH-dependent FMN reductase
GVI77_RS14100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GVI77_RS14110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GVI77_RS14115	COG1116	anion transmembrane transporter activity
GVI77_RS14120	COG0308	aminopeptidase N
GVI77_RS14140	COG1448	Aminotransferase
GVI77_RS14145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GVI77_RS14150	COG3108	Peptidase M15
GVI77_RS14155	COG2989	Protein conserved in bacteria
GVI77_RS14165	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GVI77_RS14175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GVI77_RS14180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GVI77_RS14185	COG3173	Aminoglycoside phosphotransferase
GVI77_RS14200	COG3214	Protein conserved in bacteria
GVI77_RS14215	COG2333	competence protein COMEC
GVI77_RS14215	COG0658	competence protein
GVI77_RS14225	COG0539	negative regulation of cytoplasmic translation
GVI77_RS14235	COG0501	Belongs to the peptidase M48B family
GVI77_RS14250	COG2323	membrane
GVI77_RS14255	COG1944	ATP diphosphatase activity
GVI77_RS14260	COG2116	formate transmembrane transporter activity
GVI77_RS14265	COG1882	Formate acetyltransferase
GVI77_RS14270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GVI77_RS14280	COG1335	isochorismatase
GVI77_RS14285	COG3302	dmso reductase anchor subunit
GVI77_RS14290	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS14295	COG0243	molybdopterin cofactor binding
GVI77_RS14305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GVI77_RS14320	COG1522	sequence-specific DNA binding
GVI77_RS14325	COG0492	ferredoxin-NADP+ reductase activity
GVI77_RS14330	COG4988	ABC transporter
GVI77_RS14335	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GVI77_RS14355	COG0542	response to heat
GVI77_RS14365	COG1278	Cold shock
GVI77_RS14375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS14380	COG2990	Protein conserved in bacteria
GVI77_RS14385	COG3593	DNA synthesis involved in DNA repair
GVI77_RS14390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GVI77_RS14395	COG2431	L-lysine efflux transmembrane transporter activity
GVI77_RS14400	COG1151	hydroxylamine reductase activity
GVI77_RS14405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GVI77_RS14410	COG0028	Belongs to the TPP enzyme family
GVI77_RS14415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GVI77_RS14420	COG0702	epimerase
GVI77_RS14425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GVI77_RS14430	COG3023	N-Acetylmuramoyl-L-alanine amidase
GVI77_RS14445	COG1126	abc transporter atp-binding protein
GVI77_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS14455	COG4215	(ABC) transporter
GVI77_RS14460	COG4160	amino acid transport
GVI77_RS14465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS14480	COG1177	transmembrane transport
GVI77_RS14485	COG1176	ABC-type spermidine putrescine transport system, permease component I
GVI77_RS14490	COG3842	ATPase activity
GVI77_RS14495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GVI77_RS14510	COG0778	Nitroreductase
GVI77_RS14520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GVI77_RS14535	COG3226	Transcriptional regulator
GVI77_RS14540	COG0738	Major facilitator superfamily
GVI77_RS14545	COG0561	phosphatase activity
GVI77_RS14555	COG2814	Major facilitator Superfamily
GVI77_RS14560	COG0671	phosphoesterase, PA-phosphatase related
GVI77_RS14565	COG1349	DNA-binding transcription factor activity
GVI77_RS14570	COG1686	Belongs to the peptidase S11 family
GVI77_RS14575	COG0625	glutathione transferase activity
GVI77_RS14580	COG2133	pyrroloquinoline quinone binding
GVI77_RS14595	COG2199	diguanylate cyclase activity
GVI77_RS14625	COG1446	asparaginase
GVI77_RS14630	COG0303	'Molybdopterin
GVI77_RS14635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GVI77_RS14640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GVI77_RS14645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GVI77_RS14650	COG1882	Formate acetyltransferase
GVI77_RS14655	COG0561	phosphatase activity
GVI77_RS14660	COG0488	(ABC) transporter
GVI77_RS14665	COG1376	ErfK ybiS ycfS ynhG family protein
GVI77_RS14670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GVI77_RS14675	COG1321	iron dependent repressor
GVI77_RS14685	COG2194	sulfuric ester hydrolase activity
GVI77_RS14690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GVI77_RS14700	COG5006	permease, DMT superfamily
GVI77_RS14710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS14715	COG0765	amino acid transport
GVI77_RS14720	COG1126	abc transporter atp-binding protein
GVI77_RS14725	COG0668	transmembrane transport
GVI77_RS14745	COG3128	pkhd-type hydroxylase
GVI77_RS14750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GVI77_RS14760	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GVI77_RS14765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GVI77_RS14770	COG1199	ATP-dependent helicase activity
GVI77_RS14780	COG0513	Belongs to the DEAD box helicase family
GVI77_RS14785	COG1309	transcriptional regulator
GVI77_RS14795	COG1131	(ABC) transporter
GVI77_RS14800	COG0842	Transport permease protein
GVI77_RS14805	COG0842	Transport permease protein
GVI77_RS14815	COG3568	Endonuclease Exonuclease Phosphatase
GVI77_RS14820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GVI77_RS14825	COG0392	lysyltransferase activity
GVI77_RS14830	COG0670	Belongs to the BI1 family
GVI77_RS14835	COG0670	Belongs to the BI1 family
GVI77_RS14840	COG0314	molybdopterin synthase activity
GVI77_RS14845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GVI77_RS14855	COG0521	Mo-molybdopterin cofactor biosynthetic process
GVI77_RS14865	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GVI77_RS14875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GVI77_RS14880	COG2226	methyltransferase
GVI77_RS14895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GVI77_RS14900	COG1881	PFAM PEBP family protein
GVI77_RS14905	COG4677	pectinesterase activity
GVI77_RS14910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GVI77_RS14915	COG0471	metal ion transport
GVI77_RS14920	COG2828	Protein conserved in bacteria
GVI77_RS14925	COG0583	DNA-binding transcription factor activity
GVI77_RS14935	COG0561	phosphatase activity
GVI77_RS14940	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GVI77_RS14945	COG4149	molybdate abc transporter
GVI77_RS14950	COG0725	ABC transporter, periplasmic molybdate-binding protein
GVI77_RS14960	COG3585	molybdate ion transport
GVI77_RS14960	COG2005	Transcriptional regulator
GVI77_RS14965	COG1119	ATPase activity
GVI77_RS14970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GVI77_RS14975	COG1085	galactose-1-phosphate uridylyltransferase
GVI77_RS14985	COG2017	converts alpha-aldose to the beta-anomer
GVI77_RS14995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GVI77_RS15005	COG1230	cation diffusion facilitator family transporter
GVI77_RS15010	COG3201	nicotinamide mononucleotide transporter
GVI77_RS15015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GVI77_RS15055	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GVI77_RS15060	COG2885	chlorophyll binding
GVI77_RS15070	COG3064	Membrane
GVI77_RS15075	COG0848	biopolymer transport protein
GVI77_RS15080	COG0811	peptide transport
GVI77_RS15085	COG0824	Thioesterase
GVI77_RS15090	COG3790	cyd operon protein YbgE
GVI77_RS15095	COG4890	Cyd operon protein YbgT
GVI77_RS15100	COG1294	oxidase, subunit
GVI77_RS15105	COG1271	oxidase subunit
GVI77_RS15115	COG0383	alpha-mannosidase activity
GVI77_RS15120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS15120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS15120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS15125	COG2188	Transcriptional regulator
GVI77_RS15130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GVI77_RS15140	COG0508	dehydrogenase complex catalyzes the overall conversion of
GVI77_RS15145	COG0567	Dehydrogenase, E1 component
GVI77_RS15150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GVI77_RS15155	COG1053	succinate dehydrogenase
GVI77_RS15160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GVI77_RS15165	COG2009	succinate dehydrogenase
GVI77_RS15175	COG0372	Belongs to the citrate synthase family
GVI77_RS15180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GVI77_RS15190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GVI77_RS15195	COG2721	sulfolactate sulfo-lyase activity
GVI77_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS15210	COG1063	alcohol dehydrogenase
GVI77_RS15215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GVI77_RS15215	COG0473	3-isopropylmalate dehydrogenase activity
GVI77_RS15220	COG2186	Transcriptional regulator
GVI77_RS15225	COG3180	Ammonia monooxygenase
GVI77_RS15235	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GVI77_RS15240	COG1984	allophanate hydrolase subunit 2
GVI77_RS15245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GVI77_RS15250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GVI77_RS15260	COG0415	Belongs to the DNA photolyase family
GVI77_RS15265	COG3272	Protein of unknown function (DUF1722)
GVI77_RS15295	COG2205	protein histidine kinase activity
GVI77_RS15300	COG0745	RESPONSE REGULATOR receiver
GVI77_RS15310	COG1982	Orn Lys Arg decarboxylase major
GVI77_RS15315	COG0531	amino acid
GVI77_RS15320	COG0033	Phosphoglucomutase
GVI77_RS15325	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GVI77_RS15330	COG0596	Alpha beta hydrolase
GVI77_RS15340	COG0716	FMN binding
GVI77_RS15350	COG0735	belongs to the Fur family
GVI77_RS15370	COG1349	DNA-binding transcription factor activity
GVI77_RS15375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GVI77_RS15380	COG3395	kinase activity
GVI77_RS15390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GVI77_RS15395	COG0861	Integral membrane protein TerC family
GVI77_RS15415	COG2190	(PTS) system
GVI77_RS15415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS15415	COG1263	PTS System
GVI77_RS15425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GVI77_RS15430	COG1846	Transcriptional regulator
GVI77_RS15430	COG1940	carbohydrate kinase activity
GVI77_RS15435	COG0647	UMP catabolic process
GVI77_RS15440	COG0367	asparagine synthase
GVI77_RS15485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GVI77_RS15495	COG1702	phosphate starvation-inducible protein PhoH
GVI77_RS15505	COG4535	Mg2 and Co2 transporter CorC
GVI77_RS15510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GVI77_RS15520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI77_RS15525	COG0765	amino acid transport
GVI77_RS15530	COG0765	amino acid transport
GVI77_RS15535	COG1126	abc transporter atp-binding protein
GVI77_RS15545	COG0443	Heat shock 70 kDa protein
GVI77_RS15550	COG2214	Heat shock protein DnaJ domain protein
GVI77_RS15560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GVI77_RS15570	COG2888	peptidyl-tyrosine sulfation
GVI77_RS15585	COG1466	dna polymerase III delta subunit
GVI77_RS15595	COG0406	alpha-ribazole phosphatase activity
GVI77_RS15600	COG0799	negative regulation of ribosome biogenesis
GVI77_RS15610	COG0768	penicillin binding
GVI77_RS15615	COG0772	Belongs to the SEDS family
GVI77_RS15620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GVI77_RS15625	COG1686	Belongs to the peptidase S11 family
GVI77_RS15650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GVI77_RS15655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GVI77_RS15675	COG3069	C4-dicarboxylate transmembrane transporter activity
GVI77_RS15680	COG4565	transcriptional regulatory protein
GVI77_RS15685	COG3290	protein histidine kinase activity
GVI77_RS15690	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GVI77_RS15700	COG2301	Belongs to the HpcH HpaI aldolase family
GVI77_RS15705	COG3051	citrate lyase alpha subunit
GVI77_RS15720	COG0471	metal ion transport
GVI77_RS15725	COG3719	Belongs to the RNase T2 family
GVI77_RS15730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GVI77_RS15735	COG0589	response to stress
GVI77_RS15740	COG3634	alkyl hydroperoxide reductase activity
GVI77_RS15745	COG0450	alkyl hydroperoxide reductase
GVI77_RS15750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GVI77_RS15755	COG0583	DNA-binding transcription factor activity
GVI77_RS15760	COG3969	phosphoadenosine phosphosulfate
GVI77_RS15765	COG1475	DNA binding
GVI77_RS15770	COG0436	Aminotransferase
GVI77_RS15775	COG0371	Dehydrogenase
GVI77_RS15780	COG2879	small protein
GVI77_RS15785	COG1966	Carbon starvation protein
GVI77_RS15790	COG2050	protein possibly involved in aromatic compounds catabolism
GVI77_RS15795	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS15800	COG3433	isochorismatase activity
GVI77_RS15800	COG1535	isochorismatase
GVI77_RS15805	COG1021	2,3-dihydroxybenzoate-AMP ligase
GVI77_RS15810	COG1169	isochorismate synthase
GVI77_RS15815	COG4592	Periplasmic binding protein
GVI77_RS15825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS15830	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS15835	COG1120	ATPase activity
GVI77_RS15840	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GVI77_RS15845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GVI77_RS15845	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GVI77_RS15850	COG3251	PFAM MbtH domain protein
GVI77_RS15855	COG2382	esterase
GVI77_RS15865	COG4771	TonB-dependent receptor
GVI77_RS15870	COG2977	Belongs to the P-Pant transferase superfamily
GVI77_RS15875	COG3958	Transketolase
GVI77_RS15880	COG3959	Transketolase, thiamine diphosphate binding domain
GVI77_RS15885	COG2390	Transcriptional regulator
GVI77_RS15890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GVI77_RS15895	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS15905	COG1129	ABC transporter
GVI77_RS15910	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS15920	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS15950	COG2315	Protein conserved in bacteria
GVI77_RS15955	COG0778	Nitroreductase
GVI77_RS15960	COG0668	transmembrane transport
GVI77_RS15965	COG1113	amino acid transport
GVI77_RS15970	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI77_RS15975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS15980	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS15985	COG1538	Outer membrane efflux protein
GVI77_RS15990	COG0745	RESPONSE REGULATOR receiver
GVI77_RS15995	COG5002	protein histidine kinase activity
GVI77_RS16000	COG1215	transferase activity, transferring glycosyl groups
GVI77_RS16005	COG4783	chaperone-mediated protein folding
GVI77_RS16015	COG4571	Outer membrane protease
GVI77_RS16020	COG0500	methyltransferase
GVI77_RS16050	COG2501	S4 domain
GVI77_RS16055	COG1988	membrane-bound metal-dependent
GVI77_RS16065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GVI77_RS16080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GVI77_RS16085	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GVI77_RS16090	COG0549	Belongs to the carbamate kinase family
GVI77_RS16100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GVI77_RS16105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GVI77_RS16110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GVI77_RS16115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GVI77_RS16120	COG3257	ureidoglycine aminohydrolase activity
GVI77_RS16125	COG1929	Belongs to the glycerate kinase type-1 family
GVI77_RS16130	COG2233	PERMEase
GVI77_RS16140	COG1953	Uracil, thiamine, allantoin
GVI77_RS16150	COG3622	Belongs to the hyi family
GVI77_RS16155	COG3960	tartronate-semialdehyde synthase activity
GVI77_RS16200	COG3157	Type VI secretion system effector, Hcp
GVI77_RS16205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GVI77_RS16210	COG4181	ATPase activity
GVI77_RS16215	COG2755	lipolytic protein G-D-S-L family
GVI77_RS16220	COG0300	oxidoreductase activity
GVI77_RS16225	COG3118	belongs to the thioredoxin family
GVI77_RS16230	COG0390	transport system, permease component
GVI77_RS16235	COG4619	ABC transporter
GVI77_RS16240	COG0330	HflC and HflK could
GVI77_RS16245	COG1585	Membrane protein implicated in regulation of membrane protease activity
GVI77_RS16255	COG0789	Transcriptional regulator
GVI77_RS16260	COG0531	amino acid
GVI77_RS16265	COG2066	Belongs to the glutaminase family
GVI77_RS16270	COG2217	Heavy metal translocating P-type atpase
GVI77_RS16275	COG3093	addiction module antidote protein HigA
GVI77_RS16280	COG3549	Plasmid maintenance system killer
GVI77_RS16285	COG3735	TraB family
GVI77_RS16290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GVI77_RS16305	COG0737	Belongs to the 5'-nucleotidase family
GVI77_RS16310	COG2223	nitrite transmembrane transporter activity
GVI77_RS16315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GVI77_RS16315	COG4651	solute:proton antiporter activity
GVI77_RS16320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS16355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GVI77_RS16365	COG2832	Protein of unknown function (DUF454)
GVI77_RS16370	COG3923	Primosomal replication protein n
GVI77_RS16380	COG1196	nuclear chromosome segregation
GVI77_RS16380	COG3264	Mechanosensitive ion channel
GVI77_RS16385	COG1309	transcriptional regulator
GVI77_RS16390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI77_RS16395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI77_RS16410	COG0110	maltose O-acetyltransferase activity
GVI77_RS16420	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GVI77_RS16425	COG5507	3-demethylubiquinone-9 3-methyltransferase
GVI77_RS16435	COG3695	enzyme binding
GVI77_RS16440	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GVI77_RS16445	COG1946	Acyl-CoA thioesterase
GVI77_RS16450	COG0004	ammonium transporteR
GVI77_RS16455	COG0347	Belongs to the P(II) protein family
GVI77_RS16460	COG1132	(ABC) transporter
GVI77_RS16465	COG1132	(ABC) transporter
GVI77_RS16470	COG1522	sequence-specific DNA binding
GVI77_RS16480	COG4533	DNA binding
GVI77_RS16490	COG0824	Thioesterase
GVI77_RS16495	COG1555	photosystem II stabilization
GVI77_RS16500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GVI77_RS16505	COG0776	regulation of translation
GVI77_RS16510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GVI77_RS16530	COG0271	Belongs to the BolA IbaG family
GVI77_RS16535	COG3056	Lipoprotein
GVI77_RS16540	COG2223	nitrite transmembrane transporter activity
GVI77_RS16545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GVI77_RS16550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GVI77_RS16555	COG1845	cytochrome c oxidase, subunit III
GVI77_RS16560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GVI77_RS16570	COG2814	Major facilitator Superfamily
GVI77_RS16580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GVI77_RS16585	COG0693	protein deglycase activity
GVI77_RS16600	COG0142	geranyltranstransferase activity
GVI77_RS16610	COG0667	Aldo Keto reductase
GVI77_RS16615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GVI77_RS16620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GVI77_RS16635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GVI77_RS16635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GVI77_RS16645	COG4238	major outer membrane lipoprotein
GVI77_RS16650	COG3248	Nucleoside-binding outer membrane protein
GVI77_RS16655	COG1403	HNH endonuclease
GVI77_RS16660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GVI77_RS16665	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GVI77_RS16670	COG1862	Preprotein translocase
GVI77_RS16690	COG0366	Alpha amylase catalytic
GVI77_RS16695	COG1113	amino acid transport
GVI77_RS16700	COG1114	Component of the transport system for branched-chain amino acids
GVI77_RS16705	COG5002	protein histidine kinase activity
GVI77_RS16710	COG0745	RESPONSE REGULATOR receiver
GVI77_RS16715	COG0420	3'-5' exonuclease activity
GVI77_RS16720	COG0419	ATPase involved in DNA repair
GVI77_RS16725	COG2814	Major facilitator Superfamily
GVI77_RS16730	COG1940	carbohydrate kinase activity
GVI77_RS16755	COG4126	flavin adenine dinucleotide binding
GVI77_RS16775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GVI77_RS16780	COG3706	GGDEF domain
GVI77_RS16790	COG1785	Belongs to the alkaline phosphatase family
GVI77_RS16805	COG1181	Belongs to the D-alanine--D-alanine ligase family
GVI77_RS16825	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GVI77_RS16830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GVI77_RS16835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GVI77_RS16840	COG3468	outer membrane autotransporter barrel domain protein
GVI77_RS16845	COG0113	porphobilinogen synthase activity
GVI77_RS16850	COG2175	clavaminate synthase activity
GVI77_RS16855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GVI77_RS16865	COG4521	taurine ABC transporter
GVI77_RS16885	COG3122	Protein conserved in bacteria
GVI77_RS16890	COG2814	Major facilitator Superfamily
GVI77_RS16895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GVI77_RS16925	COG1414	Transcriptional regulator
GVI77_RS16930	COG1609	Transcriptional regulator
GVI77_RS16940	COG2223	nitrite transmembrane transporter activity
GVI77_RS16945	COG0110	maltose O-acetyltransferase activity
GVI77_RS16950	COG0402	S-adenosylhomocysteine deaminase activity
GVI77_RS16955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GVI77_RS16960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GVI77_RS16965	COG2079	MmgE PrpD family protein
GVI77_RS16970	COG0372	Belongs to the citrate synthase family
GVI77_RS16975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GVI77_RS16990	COG1280	lysine exporter protein (LysE YggA)
GVI77_RS17000	COG1064	alcohol dehydrogenase
GVI77_RS17005	COG0402	S-adenosylhomocysteine deaminase activity
GVI77_RS17010	COG0549	Belongs to the carbamate kinase family
GVI77_RS17015	COG1304	FMN binding
GVI77_RS17020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GVI77_RS17030	COG0666	response to abiotic stimulus
GVI77_RS17040	COG0583	DNA-binding transcription factor activity
GVI77_RS17045	COG2200	EAL domain
GVI77_RS17045	COG2771	luxR family
GVI77_RS17050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GVI77_RS17060	COG1012	belongs to the aldehyde dehydrogenase family
GVI77_RS17070	COG0582	viral genome integration into host DNA
GVI77_RS17075	COG2200	EAL domain
GVI77_RS17075	COG2771	luxR family
GVI77_RS17100	COG3468	outer membrane autotransporter barrel domain protein
GVI77_RS17110	COG1556	Lactate utilization protein
GVI77_RS17115	COG1139	Iron-sulfur cluster binding protein
GVI77_RS17120	COG0247	lactate metabolic process
GVI77_RS17125	COG2207	Transcriptional regulator
GVI77_RS17130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GVI77_RS17140	COG3059	membrane
GVI77_RS17145	COG0656	L-ascorbic acid biosynthetic process
GVI77_RS17150	COG3708	Transcriptional regulator
GVI77_RS17150	COG2207	Transcriptional regulator
GVI77_RS17155	COG4932	domain protein
GVI77_RS17155	COG1388	LysM domain
GVI77_RS17155	COG2373	Large extracellular alpha-helical protein
GVI77_RS17160	COG0656	L-ascorbic acid biosynthetic process
GVI77_RS17165	COG0667	Aldo Keto reductase
GVI77_RS17175	COG0583	DNA-binding transcription factor activity
GVI77_RS17180	COG1073	alpha beta
GVI77_RS17185	COG1902	pentaerythritol trinitrate reductase activity
GVI77_RS17240	COG0727	PFAM Uncharacterised protein family (UPF0153)
GVI77_RS17250	COG3477	response to acidic pH
GVI77_RS17270	COG4974	Belongs to the 'phage' integrase family
GVI77_RS17295	COG0732	type I restriction modification DNA specificity domain
GVI77_RS17330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GVI77_RS17350	COG2195	Cleaves the N-terminal amino acid of tripeptides
GVI77_RS17355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GVI77_RS17360	COG1690	Belongs to the RtcB family
GVI77_RS17365	COG0454	-acetyltransferase
GVI77_RS17385	COG1943	Transposase
GVI77_RS17390	COG0791	NLP P60 protein
GVI77_RS17395	COG3034	peptidoglycan biosynthetic process
GVI77_RS17400	COG0121	glutamine amidotransferase
GVI77_RS17410	COG1960	acyl-CoA dehydrogenase activity
GVI77_RS17420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GVI77_RS17430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GVI77_RS17440	COG2226	methyltransferase
GVI77_RS17450	COG1388	LysM domain
GVI77_RS17450	COG0741	lytic transglycosylase activity
GVI77_RS17455	COG2226	methyltransferase
GVI77_RS17465	COG0583	DNA-binding transcription factor activity
GVI77_RS17470	COG0656	L-ascorbic acid biosynthetic process
GVI77_RS17505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GVI77_RS17510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GVI77_RS17515	COG2011	ABC-type metal ion transport system permease component
GVI77_RS17520	COG1464	Belongs to the NlpA lipoprotein family
GVI77_RS17530	COG1720	tRNA m6t6A37 methyltransferase activity
GVI77_RS17540	COG0791	NLP P60 protein
GVI77_RS17545	COG3015	lipoprotein NlpE involved in copper resistance
GVI77_RS17550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GVI77_RS17555	COG4681	YaeQ
GVI77_RS17565	COG4568	rho-dependent transcription termination
GVI77_RS17570	COG0037	tRNA processing
GVI77_RS17575	COG0346	lactoylglutathione lyase activity
GVI77_RS17580	COG1982	Orn Lys Arg decarboxylase major
GVI77_RS17590	COG0587	DNA-directed DNA polymerase activity
GVI77_RS17615	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GVI77_RS17620	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GVI77_RS17630	COG0750	zinc metalloprotease
GVI77_RS17635	COG0575	Belongs to the CDS family
GVI77_RS17640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GVI77_RS17645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GVI77_RS17670	COG0024	Methionine aminopeptidase
GVI77_RS17690	COG3835	regulator
GVI77_RS17695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GVI77_RS17710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GVI77_RS17715	COG2860	membrane
GVI77_RS17740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI77_RS17745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GVI77_RS17750	COG1120	ATPase activity
GVI77_RS17755	COG4774	siderophore transport
GVI77_RS17770	COG3121	Chaperone
GVI77_RS17780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GVI77_RS17785	COG1643	Atp-dependent helicase
GVI77_RS17790	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GVI77_RS17800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GVI77_RS17805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GVI77_RS17810	COG0617	tRNA 3'-terminal CCA addition
GVI77_RS17815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GVI77_RS17820	COG3539	Fimbrial protein
GVI77_RS17825	COG3121	Chaperone
GVI77_RS17830	COG3188	usher protein
GVI77_RS17835	COG3539	Fimbrial protein
GVI77_RS17840	COG3539	Fimbrial protein
GVI77_RS17845	COG3539	Fimbrial protein
GVI77_RS17850	COG3539	Fimbrial protein
GVI77_RS17860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GVI77_RS17865	COG5464	transposase or invertase
GVI77_RS17870	COG5464	transposase or invertase
GVI77_RS17880	COG0726	polysaccharide deacetylase
GVI77_RS17885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS17890	COG0842	Transport permease protein
GVI77_RS17895	COG1131	(ABC) transporter
GVI77_RS17900	COG0288	reversible hydration of carbon dioxide
GVI77_RS17905	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GVI77_RS17910	COG4993	Dehydrogenase
GVI77_RS17915	COG2132	Multicopper oxidase
GVI77_RS17940	COG1049	propionate catabolic process, 2-methylcitrate cycle
GVI77_RS17945	COG3064	Membrane
GVI77_RS17945	COG3064	Membrane
GVI77_RS17950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GVI77_RS17955	COG0508	dehydrogenase complex catalyzes the overall conversion of
GVI77_RS17960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GVI77_RS17965	COG2186	Transcriptional regulator
GVI77_RS18005	COG3157	Type VI secretion system effector, Hcp
GVI77_RS18010	COG1113	amino acid transport
GVI77_RS18015	COG3725	Membrane protein required for beta-lactamase induction
GVI77_RS18020	COG3023	N-Acetylmuramoyl-L-alanine amidase
GVI77_RS18025	COG0157	Belongs to the NadC ModD family
GVI77_RS18030	COG4969	Belongs to the N-Me-Phe pilin family
GVI77_RS18035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GVI77_RS18040	COG1459	type II secretion system
GVI77_RS18055	COG0237	dephospho-CoA kinase activity
GVI77_RS18070	COG0494	nUDIX hydrolase
GVI77_RS18090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GVI77_RS18095	COG0849	cell division
GVI77_RS18100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GVI77_RS18105	COG1181	Belongs to the D-alanine--D-alanine ligase family
GVI77_RS18120	COG0772	Belongs to the SEDS family
GVI77_RS18135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GVI77_RS18140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GVI77_RS18145	COG0768	penicillin binding
GVI77_RS18150	COG3116	cell division
GVI77_RS18165	COG1609	Transcriptional regulator
GVI77_RS18175	COG0440	acetolactate synthase activity
GVI77_RS18180	COG0028	Belongs to the TPP enzyme family
GVI77_RS18190	COG0583	DNA-binding transcription factor activity
GVI77_RS18230	COG4143	(ABC) transporter
GVI77_RS18235	COG1178	ABC-type Fe3 transport system permease component
GVI77_RS18245	COG0586	Pfam SNARE associated Golgi protein
GVI77_RS18260	COG3181	Tripartite tricarboxylate transporter family receptor
GVI77_RS18265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GVI77_RS18270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS18275	COG4977	sequence-specific DNA binding
GVI77_RS18290	COG0235	Class ii aldolase
GVI77_RS18295	COG0417	DNA replication proofreading
GVI77_RS18305	COG0564	pseudouridine synthase activity
GVI77_RS18310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GVI77_RS18320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GVI77_RS18325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GVI77_RS18355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GVI77_RS18370	COG2271	Major facilitator Superfamily
GVI77_RS18375	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GVI77_RS18380	COG0644	oxidoreductase
GVI77_RS18435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GVI77_RS18440	COG0505	Belongs to the CarA family
GVI77_RS18465	COG1047	Peptidyl-prolyl cis-trans
GVI77_RS18480	COG0196	riboflavin kinase activity
GVI77_RS18505	COG0583	DNA-binding transcription factor activity
GVI77_RS18520	COG3119	arylsulfatase activity
GVI77_RS18550	COG4735	regulation of single-species biofilm formation
GVI77_RS18555	COG1584	GPR1 FUN34 yaaH family protein
GVI77_RS18560	COG0521	Mo-molybdopterin cofactor biosynthetic process
GVI77_RS18570	COG1115	amino acid carrier protein
GVI77_RS18585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GVI77_RS18595	COG0527	aspartate kinase activity
GVI77_RS18595	COG0460	homoserine dehydrogenase
GVI77_RS18605	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GVI77_RS18615	COG0745	RESPONSE REGULATOR receiver
GVI77_RS18620	COG4452	Inner membrane protein CreD
GVI77_RS18625	COG2205	protein histidine kinase activity
GVI77_RS18630	COG0745	RESPONSE REGULATOR receiver
GVI77_RS18635	COG3045	CreA protein
GVI77_RS18640	COG2207	Transcriptional regulator
GVI77_RS18640	COG3708	Transcriptional regulator
GVI77_RS18660	COG0741	lytic transglycosylase activity
GVI77_RS18665	COG0488	(ABC) transporter
GVI77_RS18675	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GVI77_RS18680	COG1056	cytidyltransferase-related domain
GVI77_RS18680	COG3172	ATPase kinase involved in NAD metabolism
GVI77_RS18685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GVI77_RS18690	COG0560	Phosphoserine phosphatase
GVI77_RS18695	COG3726	membrane protein affecting hemolysin expression
GVI77_RS18730	COG1328	CTP reductase activity
GVI77_RS18735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GVI77_RS18740	COG0084	hydrolase, TatD family'
GVI77_RS18745	COG4667	esterase of the alpha-beta hydrolase superfamily
GVI77_RS18755	COG2823	Periplasmic or secreted lipoprotein
GVI77_RS18765	COG1011	Hydrolase
GVI77_RS18770	COG0456	acetyltransferase
GVI77_RS18775	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GVI77_RS18805	COG4114	ferric iron reductase
GVI77_RS18810	COG2197	response regulator
GVI77_RS18815	COG2197	response regulator
GVI77_RS18820	COG2966	Psort location CytoplasmicMembrane, score
GVI77_RS18835	COG1484	DNA-dependent DNA replication
GVI77_RS18850	COG1063	alcohol dehydrogenase
GVI77_RS18855	COG1802	Transcriptional regulator
GVI77_RS18860	COG2271	Major facilitator Superfamily
GVI77_RS18865	COG0840	transmembrane signaling receptor activity
GVI77_RS18870	COG1966	Carbon starvation protein
GVI77_RS18875	COG2879	small protein
GVI77_RS18880	COG0523	cobalamin synthesis protein
GVI77_RS18905	COG2814	Major facilitator Superfamily
GVI77_RS18910	COG2733	membrane
GVI77_RS18915	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GVI77_RS18920	COG1924	4 iron, 4 sulfur cluster binding
GVI77_RS18935	COG0477	Major facilitator Superfamily
GVI77_RS18945	COG3366	ferrous iron transmembrane transporter activity
GVI77_RS18950	COG0700	Nucleoside recognition
GVI77_RS18955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GVI77_RS18960	COG0583	DNA-binding transcription factor activity
GVI77_RS18985	COG2186	Transcriptional regulator
GVI77_RS18990	COG0246	Mannitol dehydrogenase
GVI77_RS19000	COG2610	gluconate transmembrane transporter activity
GVI77_RS19005	COG3539	Fimbrial protein
GVI77_RS19010	COG3539	Fimbrial protein
GVI77_RS19015	COG3539	Fimbrial protein
GVI77_RS19020	COG3188	usher protein
GVI77_RS19025	COG3121	Chaperone
GVI77_RS19030	COG3539	Fimbrial protein
GVI77_RS19040	COG4974	Belongs to the 'phage' integrase family
GVI77_RS19045	COG0582	viral genome integration into host DNA
GVI77_RS19050	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GVI77_RS19055	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GVI77_RS19075	COG3436	PFAM IS66 Orf2 family protein
GVI77_RS19080	COG4372	Transposase
GVI77_RS19100	COG3153	acetyltransferase
GVI77_RS19105	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GVI77_RS19120	COG1363	Peptidase, m42
GVI77_RS19125	COG3414	Phosphotransferase system galactitol-specific IIB component
GVI77_RS19130	COG3775	system Galactitol-specific IIC component
GVI77_RS19135	COG0434	BtpA family
GVI77_RS19140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS19145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GVI77_RS19150	COG1349	DNA-binding transcription factor activity
GVI77_RS19155	COG1414	Transcriptional regulator
GVI77_RS19160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GVI77_RS19165	COG0129	dihydroxy-acid dehydratase activity
GVI77_RS19170	COG2610	gluconate transmembrane transporter activity
GVI77_RS19175	COG2390	Transcriptional regulator
GVI77_RS19200	COG1215	transferase activity, transferring glycosyl groups
GVI77_RS19205	COG1401	restriction endodeoxyribonuclease activity
GVI77_RS19260	COG2003	Belongs to the UPF0758 family
GVI77_RS19285	COG4584	PFAM Integrase catalytic
GVI77_RS19290	COG1484	DNA-dependent DNA replication
GVI77_RS19350	COG3436	PFAM IS66 Orf2 family protein
GVI77_RS19355	COG4372	Transposase
GVI77_RS19375	COG1349	DNA-binding transcription factor activity
GVI77_RS19385	COG0738	Major facilitator superfamily
GVI77_RS19400	COG3037	sugar-specific permease SgaT UlaA
GVI77_RS19410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS19435	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GVI77_RS19440	COG2190	(PTS) system
GVI77_RS19440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS19440	COG1263	PTS System
GVI77_RS19445	COG1737	Transcriptional regulator
GVI77_RS19460	COG3177	Filamentation induced by cAMP protein fic
GVI77_RS19475	COG3335	DDE superfamily endonuclease
GVI77_RS19490	COG2205	protein histidine kinase activity
GVI77_RS19510	COG4227	nucleotidyltransferase activity
GVI77_RS19530	COG1064	alcohol dehydrogenase
GVI77_RS19535	COG3265	gluconokinase activity
GVI77_RS19540	COG1063	alcohol dehydrogenase
GVI77_RS19545	COG1028	Short-chain dehydrogenase reductase Sdr
GVI77_RS19550	COG2610	gluconate transmembrane transporter activity
GVI77_RS19555	COG1609	Transcriptional regulator
GVI77_RS19565	COG0795	lipopolysaccharide-transporting ATPase activity
GVI77_RS19570	COG0795	lipopolysaccharide-transporting ATPase activity
GVI77_RS19580	COG2927	DNA polymerase III (CHI subunit)
GVI77_RS19585	COG0525	valine-tRNA ligase activity
GVI77_RS19595	COG0456	acetyltransferase
GVI77_RS19600	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GVI77_RS19605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GVI77_RS19610	COG2731	YhcH YjgK YiaL family protein
GVI77_RS19620	COG0549	Belongs to the carbamate kinase family
GVI77_RS19625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GVI77_RS19630	COG1288	antiporter activity
GVI77_RS19635	COG1438	arginine binding
GVI77_RS19655	COG0251	oxidation-reduction process
GVI77_RS19660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GVI77_RS19670	COG1609	Transcriptional regulator
GVI77_RS19675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS19675	COG1263	PTS System
GVI77_RS19680	COG0366	Alpha amylase catalytic
GVI77_RS19685	COG1328	CTP reductase activity
GVI77_RS19690	COG0602	queuosine metabolic process
GVI77_RS19695	COG3783	Cytochrome b(562)
GVI77_RS19700	COG0312	modulator of DNA gyrase
GVI77_RS19710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GVI77_RS19720	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS19725	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS19730	COG1129	ABC transporter
GVI77_RS19735	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS19740	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GVI77_RS19745	COG2105	PFAM AIG2 family protein
GVI77_RS19750	COG2911	Protein conserved in bacteria
GVI77_RS19755	COG0729	surface antigen
GVI77_RS19765	COG1253	flavin adenine dinucleotide binding
GVI77_RS19775	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GVI77_RS19780	COG1218	3'(2'),5'-bisphosphate nucleotidase
GVI77_RS19785	COG0737	Belongs to the 5'-nucleotidase family
GVI77_RS19790	COG1733	regulation of RNA biosynthetic process
GVI77_RS19795	COG0702	epimerase
GVI77_RS19800	COG0697	spore germination
GVI77_RS19810	COG1113	amino acid transport
GVI77_RS19815	COG0545	Peptidyl-prolyl cis-trans isomerase
GVI77_RS19820	COG3061	Opacity-associated protein A
GVI77_RS19825	COG1309	transcriptional regulator
GVI77_RS19840	COG1024	Enoyl-CoA hydratase
GVI77_RS19845	COG4670	ketone body catabolic process
GVI77_RS19850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GVI77_RS19855	COG2271	Major facilitator Superfamily
GVI77_RS19875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GVI77_RS19895	COG0235	Class ii aldolase
GVI77_RS19915	COG3414	Phosphotransferase system galactitol-specific IIB component
GVI77_RS19920	COG3037	sugar-specific permease SgaT UlaA
GVI77_RS19935	COG1073	alpha beta
GVI77_RS19940	COG3650	response to hydrogen peroxide
GVI77_RS19950	COG1960	acyl-CoA dehydrogenase activity
GVI77_RS19955	COG0754	glutathionylspermidine amidase activity
GVI77_RS19960	COG5463	Belongs to the UPF0441 family
GVI77_RS19965	COG3766	membrane
GVI77_RS19975	COG1842	Phage shock protein A
GVI77_RS19980	COG3789	protein conserved in bacteria
GVI77_RS19985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GVI77_RS19990	COG0557	exoribonuclease II activity
GVI77_RS20005	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GVI77_RS20010	COG0330	HflC and HflK could
GVI77_RS20015	COG0330	HflC and HflK could
GVI77_RS20020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GVI77_RS20040	COG0860	N-Acetylmuramoyl-L-alanine amidase
GVI77_RS20045	COG0802	atpase or kinase
GVI77_RS20050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GVI77_RS20050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GVI77_RS20055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GVI77_RS20095	COG1511	domain protein
GVI77_RS20095	COG3264	Mechanosensitive ion channel
GVI77_RS20105	COG0531	amino acid
GVI77_RS20115	COG1053	succinate dehydrogenase
GVI77_RS20120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GVI77_RS20135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GVI77_RS20140	COG3040	lipid binding
GVI77_RS20145	COG2076	Multidrug Resistance protein
GVI77_RS20150	COG5510	response to toxic substance
GVI77_RS20155	COG5510	response to toxic substance
GVI77_RS20165	COG1509	lysine 2,3-aminomutase activity
GVI77_RS20190	COG0531	amino acid
GVI77_RS20195	COG3030	protein affecting phage T7 exclusion by the F plasmid
GVI77_RS20200	COG1027	Aspartate ammonia-lyase
GVI77_RS20205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GVI77_RS20215	COG4232	protein-disulfide reductase activity
GVI77_RS20220	COG1309	transcriptional regulator
GVI77_RS20230	COG3710	Transcriptional regulator
GVI77_RS20235	COG0531	amino acid
GVI77_RS20240	COG1982	Orn Lys Arg decarboxylase major
GVI77_RS20245	COG3104	oligopeptide transport
GVI77_RS20250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GVI77_RS20265	COG2388	GCN5-related N-acetyl-transferase
GVI77_RS20280	COG3468	outer membrane autotransporter barrel domain protein
GVI77_RS20280	COG3210	domain, Protein
GVI77_RS20290	COG3121	Chaperone
GVI77_RS20300	COG2388	GCN5-related N-acetyl-transferase
GVI77_RS20305	COG3592	Divergent 4Fe-4S mono-cluster
GVI77_RS20310	COG3290	protein histidine kinase activity
GVI77_RS20315	COG4565	transcriptional regulatory protein
GVI77_RS20320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GVI77_RS20325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI77_RS20325	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI77_RS20330	COG3647	Membrane
GVI77_RS20335	COG1486	melibiose metabolic process
GVI77_RS20340	COG2169	Transcriptional regulator
GVI77_RS20345	COG1982	Orn Lys Arg decarboxylase major
GVI77_RS20350	COG2207	Transcriptional regulator
GVI77_RS20355	COG0531	amino acid
GVI77_RS20360	COG2194	sulfuric ester hydrolase activity
GVI77_RS20365	COG0745	RESPONSE REGULATOR receiver
GVI77_RS20370	COG0642	Histidine kinase
GVI77_RS20380	COG0477	Major facilitator Superfamily
GVI77_RS20395	COG2824	Alkylphosphonate utilization operon protein PhnA
GVI77_RS20400	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GVI77_RS20410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GVI77_RS20415	COG3639	organic phosphonate transmembrane transporter activity
GVI77_RS20420	COG2188	Transcriptional regulator
GVI77_RS20425	COG3624	Phosphonate C-P lyase system protein PhnG
GVI77_RS20430	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GVI77_RS20435	COG3626	phosphonate metabolism
GVI77_RS20440	COG3627	carbon phosphorus lyase activity
GVI77_RS20445	COG4107	phosphonate C-P lyase system protein PhnK
GVI77_RS20450	COG4778	phosphonate C-P lyase system protein PhnL
GVI77_RS20455	COG3454	Phosphonate metabolism
GVI77_RS20465	COG0456	acetyltransferase
GVI77_RS20470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GVI77_RS20480	COG0698	ribose 5-phosphate isomerase
GVI77_RS20485	COG1737	Transcriptional regulator
GVI77_RS20490	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS20495	COG1129	ABC transporter
GVI77_RS20500	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS20505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GVI77_RS20510	COG1940	carbohydrate kinase activity
GVI77_RS20515	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GVI77_RS20525	COG1566	PFAM secretion protein HlyD family protein
GVI77_RS20530	COG1289	transmembrane transporter activity
GVI77_RS20550	COG0601	transmembrane transport
GVI77_RS20555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GVI77_RS20560	COG0444	Belongs to the ABC transporter superfamily
GVI77_RS20565	COG4608	Belongs to the ABC transporter superfamily
GVI77_RS20570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GVI77_RS20575	COG1301	dicarboxylic acid transport
GVI77_RS20580	COG4235	cytochrome complex assembly
GVI77_RS20585	COG3088	subunit of a heme lyase
GVI77_RS20590	COG1138	Cytochrome C-type biogenesis protein
GVI77_RS20595	COG3301	Polysulphide reductase, NrfD
GVI77_RS20600	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS20605	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GVI77_RS20615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GVI77_RS20620	COG3162	membrane
GVI77_RS20630	COG1346	cytolysis
GVI77_RS20635	COG1380	Effector of murein hydrolase LrgA
GVI77_RS20640	COG0583	DNA-binding transcription factor activity
GVI77_RS20645	COG0025	NhaP-type Na H and K H
GVI77_RS20650	COG2252	PERMEase
GVI77_RS20655	COG0789	Transcriptional regulator
GVI77_RS20660	COG2207	Transcriptional regulator
GVI77_RS20665	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GVI77_RS20675	COG0629	single-stranded DNA binding
GVI77_RS20680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GVI77_RS20685	COG2315	Protein conserved in bacteria
GVI77_RS20690	COG0432	Pfam Uncharacterised protein family UPF0047
GVI77_RS20695	COG3700	Belongs to the class B bacterial acid phosphatase family
GVI77_RS20705	COG2204	response regulator
GVI77_RS20710	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GVI77_RS20715	COG0471	metal ion transport
GVI77_RS20720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GVI77_RS20725	COG0045	succinate-CoA ligase (ADP-forming) activity
GVI77_RS20730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GVI77_RS20740	COG0567	Dehydrogenase, E1 component
GVI77_RS20745	COG1448	Aminotransferase
GVI77_RS20755	COG3201	nicotinamide mononucleotide transporter
GVI77_RS20760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GVI77_RS20765	COG0305	Participates in initiation and elongation during chromosome replication
GVI77_RS20770	COG1609	Transcriptional regulator
GVI77_RS20780	COG1024	Enoyl-CoA hydratase
GVI77_RS20785	COG1914	H( )-stimulated, divalent metal cation uptake system
GVI77_RS20790	COG1053	succinate dehydrogenase
GVI77_RS20795	COG0604	alcohol dehydrogenase
GVI77_RS20805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GVI77_RS20810	COG0735	belongs to the Fur family
GVI77_RS20815	COG3237	CsbD-like
GVI77_RS20820	COG0534	Mate efflux family protein
GVI77_RS20830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GVI77_RS20860	COG3842	ATPase activity
GVI77_RS20865	COG2182	Extracellular solute-binding protein
GVI77_RS20870	COG1175	transmembrane transport
GVI77_RS20875	COG3833	ABC-type maltose transport systems, permease component
GVI77_RS20890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI77_RS20915	COG0527	aspartate kinase activity
GVI77_RS20925	COG1187	pseudouridine synthase activity
GVI77_RS20970	COG1283	sodium-dependent phosphate transmembrane transporter activity
GVI77_RS20980	COG1410	methionine synthase
GVI77_RS20980	COG0646	methionine synthase
GVI77_RS20985	COG1414	Transcriptional regulator
GVI77_RS20995	COG2224	Isocitrate lyase
GVI77_RS21000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GVI77_RS21010	COG0456	acetyltransferase
GVI77_RS21045	COG0151	Belongs to the GarS family
GVI77_RS21050	COG2204	response regulator
GVI77_RS21055	COG4191	Histidine kinase
GVI77_RS21060	COG3678	ATP-independent chaperone mediated protein folding
GVI77_RS21075	COG3068	Protein conserved in bacteria
GVI77_RS21110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GVI77_RS21115	COG2104	thiamine diphosphate biosynthetic process
GVI77_RS21125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GVI77_RS21160	COG0250	Participates in transcription elongation, termination and antitermination
GVI77_RS21165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GVI77_RS21200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GVI77_RS21200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GVI77_RS21255	COG1309	transcriptional regulator
GVI77_RS21260	COG0477	Major facilitator Superfamily
GVI77_RS21265	COG1473	amidohydrolase
GVI77_RS21275	COG0583	DNA-binding transcription factor activity
GVI77_RS21290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GVI77_RS21305	COG2194	sulfuric ester hydrolase activity
GVI77_RS21310	COG2207	Transcriptional regulator
GVI77_RS21315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS21320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GVI77_RS21325	COG1882	Formate acetyltransferase
GVI77_RS21330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS21335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS21340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS21340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GVI77_RS21340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS21345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GVI77_RS21350	COG0371	Dehydrogenase
GVI77_RS21355	COG3738	Protein conserved in bacteria
GVI77_RS21360	COG0697	spore germination
GVI77_RS21370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GVI77_RS21375	COG0737	Belongs to the 5'-nucleotidase family
GVI77_RS21385	COG0460	homoserine dehydrogenase
GVI77_RS21385	COG0527	aspartate kinase activity
GVI77_RS21390	COG0626	cystathionine gamma-synthase activity
GVI77_RS21400	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GVI77_RS21410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GVI77_RS21415	COG1609	Transcriptional regulator
GVI77_RS21420	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GVI77_RS21435	COG1575	Belongs to the MenA family. Type 1 subfamily
GVI77_RS21450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GVI77_RS21460	COG1494	fructose-1,6-bisphosphatase
GVI77_RS21470	COG0589	response to stress
GVI77_RS21475	COG3691	Protein conserved in bacteria
GVI77_RS21480	COG3152	Membrane
GVI77_RS21500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GVI77_RS21515	COG3678	ATP-independent chaperone mediated protein folding
GVI77_RS21520	COG0745	RESPONSE REGULATOR receiver
GVI77_RS21525	COG2205	protein histidine kinase activity
GVI77_RS21530	COG2258	MOSC domain
GVI77_RS21540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GVI77_RS21585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS21590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS21590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI77_RS21595	COG1363	Peptidase, m42
GVI77_RS21600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI77_RS21600	COG3711	transcriptional antiterminator
GVI77_RS21615	COG0326	Molecular chaperone. Has ATPase activity
GVI77_RS21630	COG0437	4 iron, 4 sulfur cluster binding
GVI77_RS21635	COG2864	formate dehydrogenase
GVI77_RS21645	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GVI77_RS21660	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GVI77_RS21685	COG0456	acetyltransferase
GVI77_RS21700	COG1011	Hydrolase
GVI77_RS21705	COG1349	DNA-binding transcription factor activity
GVI77_RS21710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS21715	COG2084	Dehydrogenase
GVI77_RS21720	COG3684	Belongs to the aldolase LacD family
GVI77_RS21725	COG2942	2-epimerase
GVI77_RS21730	COG2017	converts alpha-aldose to the beta-anomer
GVI77_RS21740	COG1501	Belongs to the glycosyl hydrolase 31 family
GVI77_RS21745	COG2211	Major facilitator Superfamily
GVI77_RS21750	COG2211	Major facilitator Superfamily
GVI77_RS21755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GVI77_RS21760	COG1217	gtp-binding protein TYPA
GVI77_RS21765	COG0174	glutamine synthetase
GVI77_RS21770	COG3852	Histidine kinase
GVI77_RS21775	COG2204	response regulator
GVI77_RS21785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GVI77_RS21800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GVI77_RS21800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GVI77_RS21805	COG0204	Acyl-transferase
GVI77_RS21810	COG5339	Protein conserved in bacteria
GVI77_RS21815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GVI77_RS21820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GVI77_RS21825	COG3084	Protein conserved in bacteria
GVI77_RS21830	COG0746	molybdenum cofactor guanylyltransferase activity
GVI77_RS21835	COG1763	Mo-molybdopterin cofactor biosynthetic process
GVI77_RS21860	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GVI77_RS21865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GVI77_RS21870	COG1739	Uncharacterized protein family UPF0029
GVI77_RS21890	COG0543	2 iron, 2 sulfur cluster binding
GVI77_RS21895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GVI77_RS21910	COG0805	protein transport
GVI77_RS21920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GVI77_RS21930	COG3165	ubiquinone biosynthetic process from chorismate
GVI77_RS21940	COG1322	Protein conserved in bacteria
GVI77_RS21945	COG1414	Transcriptional regulator
GVI77_RS21950	COG3734	2-keto-3-deoxy-galactonokinase
GVI77_RS21955	COG0800	Aldolase
GVI77_RS21975	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GVI77_RS21980	COG0412	Dienelactone hydrolase
GVI77_RS21985	COG1335	isochorismatase
GVI77_RS21995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GVI77_RS22000	COG1304	FMN binding
GVI77_RS22005	COG0549	Belongs to the carbamate kinase family
GVI77_RS22015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GVI77_RS22020	COG0583	DNA-binding transcription factor activity
GVI77_RS22025	COG1737	Transcriptional regulator
GVI77_RS22030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GVI77_RS22035	COG2190	(PTS) system
GVI77_RS22035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS22035	COG1263	PTS System
GVI77_RS22050	COG0583	DNA-binding transcription factor activity
GVI77_RS22055	COG0697	spore germination
GVI77_RS22060	COG0561	phosphatase activity
GVI77_RS22065	COG2267	carboxylic ester hydrolase activity
GVI77_RS22070	COG1280	lysine exporter protein (LysE YggA)
GVI77_RS22080	COG1280	lysine exporter protein (LysE YggA)
GVI77_RS22085	COG0514	ATP-dependent DNA helicase (RecQ)
GVI77_RS22090	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GVI77_RS22095	COG2050	protein possibly involved in aromatic compounds catabolism
GVI77_RS22100	COG2962	Rard protein
GVI77_RS22115	COG0598	Magnesium transport protein CorA
GVI77_RS22120	COG3698	Phosphodiester glycosidase
GVI77_RS22125	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GVI77_RS22130	COG0210	DNA helicase
GVI77_RS22135	COG1011	Hydrolase
GVI77_RS22145	COG3159	Protein conserved in bacteria
GVI77_RS22155	COG5567	small periplasmic lipoprotein
GVI77_RS22170	COG3072	Adenylate cyclase
GVI77_RS22180	COG1587	Uroporphyrinogen-III synthase
GVI77_RS22185	COG2959	enzyme of heme biosynthesis
GVI77_RS22190	COG3071	HemY protein
GVI77_RS22200	COG3119	arylsulfatase activity
GVI77_RS22205	COG0641	radical SAM
GVI77_RS22230	COG1113	amino acid transport
GVI77_RS22250	COG2244	polysaccharide biosynthetic process
GVI77_RS22255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GVI77_RS22260	COG0456	acetyltransferase
GVI77_RS22265	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GVI77_RS22270	COG1088	dTDP-glucose 4,6-dehydratase activity
GVI77_RS22275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GVI77_RS22280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GVI77_RS22285	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GVI77_RS22290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GVI77_RS22295	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GVI77_RS22305	COG3118	belongs to the thioredoxin family
GVI77_RS22320	COG0210	DNA helicase
GVI77_RS22325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GVI77_RS22335	COG0583	DNA-binding transcription factor activity
GVI77_RS22340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GVI77_RS22350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GVI77_RS22355	COG3978	acetolactate synthase activity
GVI77_RS22375	COG0606	chelatase, subunit chli
GVI77_RS22380	COG3085	chromosome segregation
GVI77_RS22420	COG2186	Transcriptional regulator
GVI77_RS22425	COG0477	Major facilitator Superfamily
GVI77_RS22430	COG1609	Transcriptional regulator
GVI77_RS22435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI77_RS22440	COG1879	ABC-type sugar transport system periplasmic component
GVI77_RS22445	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI77_RS22450	COG1129	ABC transporter
GVI77_RS22455	COG1869	D-ribose catabolic process
GVI77_RS22480	COG1522	sequence-specific DNA binding
GVI77_RS22485	COG0716	FMN binding
GVI77_RS22500	COG3312	ion transport
GVI77_RS22555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GVI77_RS22560	COG0573	inorganic phosphate transmembrane transporter activity
GVI77_RS22565	COG0581	inorganic phosphate transmembrane transporter activity
GVI77_RS22570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GVI77_RS22575	COG0704	Plays a role in the regulation of phosphate uptake
GVI77_RS22580	COG3711	transcriptional antiterminator
GVI77_RS22585	COG1263	PTS System
GVI77_RS22585	COG2190	(PTS) system
GVI77_RS22585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI77_RS22590	COG2723	6-phospho-beta-galactosidase activity
GVI77_RS22595	COG4580	involved in the transport of maltose and maltodextrins
GVI77_RS22600	COG2382	esterase
GVI77_RS22605	COG0363	glucosamine-6-phosphate deaminase activity
GVI77_RS22610	COG3196	Protein conserved in bacteria
GVI77_RS22620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI77_RS22625	COG2252	PERMEase
GVI77_RS22630	COG0431	NADPH-dependent FMN reductase
GVI77_RS22635	COG2091	lysine biosynthetic process via aminoadipic acid
GVI77_RS22640	COG0583	DNA-binding transcription factor activity
GVI77_RS22650	COG0814	amino acid
GVI77_RS22745	COG0616	signal peptide processing
GVI77_RS22775	COG1525	nuclease
GVI77_RS22805	COG1192	Involved in chromosome partitioning
GVI77_RS22870	COG3039	Transposase
GVI77_RS22895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GVI77_RS22990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GVI77_RS23050	COG0714	Associated with various cellular activities
GVI77_RS23105	COG0633	Ferredoxin
GVI77_RS23255	COG3550	peptidyl-serine autophosphorylation
GVI77_RS23330	COG3173	Aminoglycoside phosphotransferase
GVI77_RS23345	COG1349	DNA-binding transcription factor activity
GVI77_RS23360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GVI77_RS23465	COG0789	Transcriptional regulator
GVI77_RS23615	COG4771	TonB-dependent receptor
GVI77_RS23645	COG3436	PFAM IS66 Orf2 family protein
GVI77_RS23660	COG3344	reverse transcriptase
GVI77_RS23725	COG1484	DNA-dependent DNA replication
GVI77_RS23730	COG4584	PFAM Integrase catalytic
GVI77_RS23765	COG1136	(ABC) transporter
GVI77_RS23765	COG0577	efflux transmembrane transporter activity
GVI77_RS23770	COG1136	(ABC) transporter
GVI77_RS23770	COG0577	efflux transmembrane transporter activity
GVI77_RS23775	COG0577	efflux transmembrane transporter activity
GVI77_RS23775	COG1136	(ABC) transporter
GVI77_RS23790	COG0672	)-iron permease
GVI77_RS23795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GVI77_RS23800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GVI77_RS23830	COG0640	Transcriptional regulator
GVI77_RS24125	COG1484	DNA-dependent DNA replication
GVI77_RS24130	COG4584	PFAM Integrase catalytic
GVI77_RS24145	COG1475	DNA binding
GVI77_RS24465	COG1475	DNA binding
GVI77_RS24890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GVI77_RS24920	COG2003	Belongs to the UPF0758 family
GVI77_RS24985	COG0629	single-stranded DNA binding