locus-tag	class	description
CO703_RS00010	COG3436	PFAM IS66 Orf2 family protein
CO703_RS00015	COG4372	Transposase
CO703_RS00030	COG2801	Transposase and inactivated derivatives
CO703_RS00035	COG2963	transposase activity
CO703_RS00050	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CO703_RS00055	COG3039	Transposase
CO703_RS00100	COG3344	reverse transcriptase
CO703_RS00105	COG3385	transposase activity
CO703_RS00125	COG3039	Transposase
CO703_RS00180	COG0577	efflux transmembrane transporter activity
CO703_RS00180	COG1136	(ABC) transporter
CO703_RS00190	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS00200	COG3436	PFAM IS66 Orf2 family protein
CO703_RS00275	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CO703_RS00285	COG3436	PFAM IS66 Orf2 family protein
CO703_RS00295	COG4372	Transposase
CO703_RS00300	COG3436	PFAM IS66 Orf2 family protein
CO703_RS00325	COG3039	Transposase
CO703_RS00525	COG0583	DNA-binding transcription factor activity
CO703_RS00530	COG0427	acetyl-CoA hydrolase
CO703_RS00535	COG1024	Enoyl-CoA hydratase
CO703_RS00540	COG1703	isobutyryl-CoA mutase activity
CO703_RS00570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CO703_RS00585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CO703_RS00610	COG0006	proline dipeptidase activity
CO703_RS00615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CO703_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CO703_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS00645	COG2723	6-phospho-beta-galactosidase activity
CO703_RS00655	COG1272	protein, Hemolysin III
CO703_RS00665	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CO703_RS00675	COG0716	FMN binding
CO703_RS00680	COG4974	Belongs to the 'phage' integrase family
CO703_RS00685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CO703_RS00690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CO703_RS00715	COG2233	PERMEase
CO703_RS00725	COG0493	'glutamate synthase
CO703_RS00725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS00730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS00735	COG2252	PERMEase
CO703_RS00740	COG0402	S-adenosylhomocysteine deaminase activity
CO703_RS00745	COG2233	PERMEase
CO703_RS00750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CO703_RS00750	COG2080	2 iron, 2 sulfur cluster binding
CO703_RS00755	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CO703_RS00760	COG0402	S-adenosylhomocysteine deaminase activity
CO703_RS00765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS00765	COG0493	'glutamate synthase
CO703_RS00770	COG2068	MobA-Related Protein
CO703_RS00775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CO703_RS00780	COG3608	succinylglutamate desuccinylase aspartoacylase
CO703_RS00780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CO703_RS00785	COG0549	Belongs to the carbamate kinase family
CO703_RS00795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CO703_RS00800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CO703_RS00805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CO703_RS00810	COG3829	transcription factor binding
CO703_RS00815	COG2080	2 iron, 2 sulfur cluster binding
CO703_RS00820	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CO703_RS00825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CO703_RS00835	COG4942	peptidase
CO703_RS00845	COG3387	PFAM Glycoside hydrolase 15-related
CO703_RS00930	COG2197	response regulator
CO703_RS00935	COG2197	response regulator
CO703_RS00955	COG0457	Tetratricopeptide repeat
CO703_RS00955	COG3710	Transcriptional regulator
CO703_RS00960	COG0457	Tetratricopeptide repeat
CO703_RS00990	COG3710	Transcriptional regulator
CO703_RS00995	COG2771	luxR family
CO703_RS01000	COG0814	amino acid
CO703_RS01005	COG0183	Belongs to the thiolase family
CO703_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS01020	COG2814	Major facilitator Superfamily
CO703_RS01025	COG1794	racemase activity, acting on amino acids and derivatives
CO703_RS01030	COG0583	DNA-binding transcription factor activity
CO703_RS01040	COG1609	Transcriptional regulator
CO703_RS01055	COG0667	Aldo Keto reductase
CO703_RS01065	COG0861	Integral membrane protein TerC family
CO703_RS01080	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CO703_RS01095	COG2165	general secretion pathway protein
CO703_RS01100	COG4795	General secretion pathway protein
CO703_RS01110	COG4967	type IV pilus modification protein PilV
CO703_RS01115	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CO703_RS01120	COG1025	Belongs to the peptidase M16 family
CO703_RS01125	COG1074	ATP-dependent DNA helicase activity
CO703_RS01130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CO703_RS01135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CO703_RS01135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CO703_RS01140	COG0860	N-Acetylmuramoyl-L-alanine amidase
CO703_RS01165	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CO703_RS01170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CO703_RS01175	COG2166	iron-sulfur cluster assembly
CO703_RS01180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CO703_RS01190	COG0583	DNA-binding transcription factor activity
CO703_RS01195	COG2363	Small membrane protein
CO703_RS01205	COG1349	DNA-binding transcription factor activity
CO703_RS01215	COG1070	Carbohydrate kinase
CO703_RS01225	COG0738	Major facilitator superfamily
CO703_RS01230	COG0235	Class ii aldolase
CO703_RS01235	COG1454	alcohol dehydrogenase
CO703_RS01245	COG1760	l-serine dehydratase
CO703_RS01250	COG0814	amino acid
CO703_RS01255	COG1611	Belongs to the LOG family
CO703_RS01270	COG3098	single-species biofilm formation
CO703_RS01280	COG0716	FMN binding
CO703_RS01285	COG2271	Major facilitator Superfamily
CO703_RS01290	COG4948	Mandelate Racemase Muconate Lactonizing
CO703_RS01295	COG4948	Mandelate Racemase Muconate Lactonizing
CO703_RS01300	COG4948	Mandelate Racemase Muconate Lactonizing
CO703_RS01305	COG4999	Histidine kinase
CO703_RS01305	COG2205	protein histidine kinase activity
CO703_RS01305	COG3850	Histidine kinase
CO703_RS01305	COG3437	response regulator, receiver
CO703_RS01315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CO703_RS01320	COG2336	PFAM SpoVT AbrB
CO703_RS01325	COG2337	Toxic component of a toxin-antitoxin (TA) module
CO703_RS01330	COG3956	TIGRFAM MazG family protein
CO703_RS01355	COG0602	queuosine metabolic process
CO703_RS01360	COG1070	Carbohydrate kinase
CO703_RS01365	COG2223	nitrite transmembrane transporter activity
CO703_RS01370	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS01375	COG0277	FAD linked oxidase domain protein
CO703_RS01380	COG0477	Major facilitator Superfamily
CO703_RS01385	COG2086	electron transfer activity
CO703_RS01390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CO703_RS01395	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CO703_RS01400	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CO703_RS01405	COG0644	oxidoreductase
CO703_RS01410	COG0720	synthase
CO703_RS01440	COG3385	transposase activity
CO703_RS01445	COG1203	CRISPR-associated helicase, Cas3
CO703_RS01460	COG1857	crispr-associated protein
CO703_RS01475	COG1518	maintenance of DNA repeat elements
CO703_RS01480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO703_RS01485	COG2234	aminopeptidase activity
CO703_RS01540	COG1388	LysM domain
CO703_RS01540	COG4942	peptidase
CO703_RS01545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CO703_RS01560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CO703_RS01570	COG2610	gluconate transmembrane transporter activity
CO703_RS01575	COG3622	Belongs to the hyi family
CO703_RS01580	COG0235	Class ii aldolase
CO703_RS01585	COG3395	kinase activity
CO703_RS01590	COG2084	Dehydrogenase
CO703_RS01595	COG1349	DNA-binding transcription factor activity
CO703_RS01600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CO703_RS01620	COG3604	Transcriptional regulator
CO703_RS01625	COG0309	Hydrogenase expression formation protein (HypE)
CO703_RS01630	COG0409	Hydrogenase expression formation protein
CO703_RS01635	COG0298	carbon dioxide binding
CO703_RS01640	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CO703_RS01645	COG0375	protein maturation
CO703_RS01660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS01665	COG0651	ATP synthesis coupled electron transport
CO703_RS01670	COG0650	Formate hydrogenlyase subunit 4
CO703_RS01675	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CO703_RS01675	COG3261	NADH dehydrogenase
CO703_RS01680	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO703_RS01685	COG3260	NADH ubiquinone oxidoreductase 20
CO703_RS01695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CO703_RS01705	COG5499	transcription regulator containing HTH domain
CO703_RS01715	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS01720	COG2723	6-phospho-beta-galactosidase activity
CO703_RS01725	COG1263	PTS System
CO703_RS01725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS01730	COG1609	Transcriptional regulator
CO703_RS01735	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS01740	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CO703_RS01760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CO703_RS01760	COG0517	IMP dehydrogenase activity
CO703_RS01765	COG1349	DNA-binding transcription factor activity
CO703_RS01770	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS01785	COG3732	PTS system glucitol sorbitol-specific
CO703_RS01790	COG3730	PTS system glucitol sorbitol-specific
CO703_RS01795	COG2951	lytic endotransglycosylase activity
CO703_RS01800	COG1546	Belongs to the CinA family
CO703_RS01820	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CO703_RS01850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO703_RS01855	COG1238	metal cluster binding
CO703_RS01870	COG2814	Major facilitator Superfamily
CO703_RS01875	COG1566	PFAM secretion protein HlyD family protein
CO703_RS01880	COG1846	Transcriptional regulator
CO703_RS01890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CO703_RS01895	COG2814	Major facilitator Superfamily
CO703_RS01900	COG2113	Glycine betaine
CO703_RS01905	COG4176	ABC-type proline glycine betaine transport system permease component
CO703_RS01910	COG4175	Glycine betaine
CO703_RS01915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CO703_RS01920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CO703_RS01930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CO703_RS01935	COG4575	ribosome binding
CO703_RS01950	COG2916	Histone family protein nucleoid-structuring protein H-NS
CO703_RS01955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CO703_RS01960	COG0640	Transcriptional regulator
CO703_RS01965	COG0401	homolog of Blt101
CO703_RS01970	COG1652	LysM domain
CO703_RS01975	COG1802	Transcriptional regulator
CO703_RS01980	COG1113	amino acid transport
CO703_RS01985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CO703_RS01990	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS01995	COG0579	oxidoreductase
CO703_RS02005	COG0366	Alpha amylase catalytic
CO703_RS02045	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS02055	COG3596	GTP binding
CO703_RS02060	COG3311	Transcriptional regulator
CO703_RS02090	COG0582	viral genome integration into host DNA
CO703_RS02105	COG2867	negative regulation of translational initiation
CO703_RS02115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO703_RS02120	COG0497	DNA recombination
CO703_RS02140	COG4536	flavin adenine dinucleotide binding
CO703_RS02145	COG4137	Cytochrome C assembly protein
CO703_RS02150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CO703_RS02175	COG2885	chlorophyll binding
CO703_RS02180	COG2199	diguanylate cyclase activity
CO703_RS02195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CO703_RS02200	COG1605	Chorismate mutase
CO703_RS02200	COG0287	Prephenate dehydrogenase
CO703_RS02205	COG0077	Prephenate dehydratase
CO703_RS02205	COG1605	Chorismate mutase
CO703_RS02210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CO703_RS02220	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO703_RS02225	COG0564	pseudouridine synthase activity
CO703_RS02230	COG1496	oxidoreductase activity
CO703_RS02235	COG0542	response to heat
CO703_RS02265	COG0477	Major facilitator Superfamily
CO703_RS02270	COG5544	Lipoprotein
CO703_RS02275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CO703_RS02280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO703_RS02280	COG1042	CoA-binding domain protein
CO703_RS02280	COG0045	succinate-CoA ligase (ADP-forming) activity
CO703_RS02285	COG3148	PFAM DTW domain containing protein
CO703_RS02290	COG3118	belongs to the thioredoxin family
CO703_RS02300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CO703_RS02320	COG0583	DNA-binding transcription factor activity
CO703_RS02325	COG0513	Belongs to the DEAD box helicase family
CO703_RS02335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CO703_RS02340	COG1595	DNA-templated transcription, initiation
CO703_RS02345	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CO703_RS02350	COG3026	antisigma factor binding
CO703_RS02355	COG3086	response to oxidative stress
CO703_RS02365	COG0681	Belongs to the peptidase S26 family
CO703_RS02390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CO703_RS02415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS02420	COG1737	Transcriptional regulator
CO703_RS02425	COG0560	Phosphoserine phosphatase
CO703_RS02445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CO703_RS02445	COG0047	phosphoribosylformylglycinamidine synthase activity
CO703_RS02450	COG2205	protein histidine kinase activity
CO703_RS02455	COG3170	Tfp pilus assembly protein FimV
CO703_RS02460	COG2204	response regulator
CO703_RS02465	COG0347	Belongs to the P(II) protein family
CO703_RS02470	COG1017	nitric oxide dioxygenase activity
CO703_RS02470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO703_RS02480	COG1940	carbohydrate kinase activity
CO703_RS02485	COG0457	Tetratricopeptide repeat
CO703_RS02490	COG1879	ABC-type sugar transport system periplasmic component
CO703_RS02495	COG1129	ABC transporter
CO703_RS02500	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO703_RS02505	COG1063	alcohol dehydrogenase
CO703_RS02510	COG2017	converts alpha-aldose to the beta-anomer
CO703_RS02515	COG2259	Doxx family
CO703_RS02540	COG4638	Rieske (2fe-2S)
CO703_RS02545	COG0583	DNA-binding transcription factor activity
CO703_RS02550	COG2814	Major facilitator Superfamily
CO703_RS02555	COG3711	transcriptional antiterminator
CO703_RS02560	COG1073	alpha beta
CO703_RS02565	COG0483	inositol monophosphate 1-phosphatase activity
CO703_RS02585	COG0822	iron-sulfur transferase activity
CO703_RS02605	COG0633	Ferredoxin
CO703_RS02610	COG2975	iron-sulfur cluster assembly
CO703_RS02625	COG2897	thiosulfate sulfurtransferase activity
CO703_RS02630	COG2373	Large extracellular alpha-helical protein
CO703_RS02635	COG4953	penicillin-binding protein 1C
CO703_RS02665	COG2976	Protein conserved in bacteria
CO703_RS02680	COG1645	bacterial-type flagellum-dependent swarming motility
CO703_RS02690	COG0516	GMP reductase activity
CO703_RS02690	COG0517	IMP dehydrogenase activity
CO703_RS02705	COG3133	Outer membrane lipoprotein
CO703_RS02725	COG2200	EAL domain
CO703_RS02730	COG0248	Ppx GppA phosphatase
CO703_RS02735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CO703_RS02740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CO703_RS02760	COG2233	PERMEase
CO703_RS02770	COG1393	Belongs to the ArsC family
CO703_RS02775	COG4783	chaperone-mediated protein folding
CO703_RS02780	COG0628	permease
CO703_RS02795	COG3604	Transcriptional regulator
CO703_RS02805	COG3260	NADH ubiquinone oxidoreductase 20
CO703_RS02810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO703_RS02815	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CO703_RS02815	COG3261	NADH dehydrogenase
CO703_RS02820	COG0651	ATP synthesis coupled electron transport
CO703_RS02825	COG4237	Hydrogenase 4 membrane
CO703_RS02835	COG0650	Formate hydrogenlyase subunit 4
CO703_RS02840	COG0650	Formate hydrogenlyase subunit 4
CO703_RS02845	COG0651	ATP synthesis coupled electron transport
CO703_RS02850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS02855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CO703_RS02860	COG2716	regulation of RNA biosynthetic process
CO703_RS02870	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CO703_RS02890	COG2321	neutral zinc metallopeptidase
CO703_RS02895	COG1444	tRNA N-acetyltransferase activity
CO703_RS02900	COG0400	carboxylic ester hydrolase activity
CO703_RS02915	COG1393	Belongs to the ArsC family
CO703_RS02925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO703_RS02930	COG3850	Histidine kinase
CO703_RS02935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS02935	COG0493	'glutamate synthase
CO703_RS02945	COG5342	invasion associated locus B
CO703_RS02950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CO703_RS02955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CO703_RS02965	COG0281	malic enzyme
CO703_RS02965	COG0280	phosphate acetyltransferase
CO703_RS02975	COG4810	utilization protein
CO703_RS02980	COG4917	ethanolamine utilization protein
CO703_RS02985	COG4766	ethanolamine catabolic process
CO703_RS02990	COG4812	Cobalamin adenosyltransferase
CO703_RS02995	COG0280	phosphate acetyltransferase
CO703_RS03000	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CO703_RS03005	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CO703_RS03010	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS03015	COG4820	ethanolamine utilization protein (EutJ)
CO703_RS03020	COG1454	alcohol dehydrogenase
CO703_RS03025	COG3192	ethanolamine utilization protein
CO703_RS03030	COG4819	ethanolamine utilization protein
CO703_RS03035	COG4303	Ethanolamine ammonia lyase large subunit
CO703_RS03045	COG4816	utilization protein
CO703_RS03050	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CO703_RS03055	COG2207	Transcriptional regulator
CO703_RS03065	COG0860	N-Acetylmuramoyl-L-alanine amidase
CO703_RS03085	COG2837	iron assimilation
CO703_RS03090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CO703_RS03095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS03095	COG1263	PTS System
CO703_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS03115	COG4150	thiosulfate binding
CO703_RS03120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CO703_RS03125	COG4208	sulfate ABC transporter
CO703_RS03130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CO703_RS03135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CO703_RS03150	COG2190	(PTS) system
CO703_RS03155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO703_RS03160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS03165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CO703_RS03185	COG3530	Putative quorum-sensing-regulated virulence factor
CO703_RS03190	COG0385	Bile acid
CO703_RS03195	COG0583	DNA-binding transcription factor activity
CO703_RS03205	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CO703_RS03210	COG2211	Major facilitator Superfamily
CO703_RS03220	COG0583	DNA-binding transcription factor activity
CO703_RS03255	COG3415	Transposase
CO703_RS03260	COG3415	Transposase
CO703_RS03275	COG2200	EAL domain
CO703_RS03275	COG2199	diguanylate cyclase activity
CO703_RS03280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CO703_RS03305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS03310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS03315	COG0006	proline dipeptidase activity
CO703_RS03320	COG1363	Peptidase, m42
CO703_RS03335	COG3039	Transposase
CO703_RS03350	COG3279	Response regulator of the LytR AlgR family
CO703_RS03355	COG3275	phosphorelay sensor kinase activity
CO703_RS03360	COG0436	Aminotransferase
CO703_RS03365	COG1560	Kdo2-lipid A biosynthetic process
CO703_RS03390	COG0028	Belongs to the TPP enzyme family
CO703_RS03395	COG0679	Auxin Efflux Carrier
CO703_RS03400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CO703_RS03405	COG2205	protein histidine kinase activity
CO703_RS03405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS03405	COG0784	Response regulator, receiver
CO703_RS03405	COG2198	Histidine kinase
CO703_RS03410	COG2197	response regulator
CO703_RS03415	COG1566	PFAM secretion protein HlyD family protein
CO703_RS03420	COG0477	Major facilitator Superfamily
CO703_RS03545	COG1783	phage Terminase large subunit
CO703_RS03640	COG0582	viral genome integration into host DNA
CO703_RS03650	COG2116	formate transmembrane transporter activity
CO703_RS03660	COG2853	Lipoprotein
CO703_RS03675	COG2067	long-chain fatty acid transport protein
CO703_RS03685	COG3691	Protein conserved in bacteria
CO703_RS03700	COG2062	phosphohistidine phosphatase, SixA
CO703_RS03705	COG3539	Fimbrial protein
CO703_RS03710	COG3188	usher protein
CO703_RS03715	COG3121	Chaperone
CO703_RS03720	COG3539	Fimbrial protein
CO703_RS03725	COG3539	Fimbrial protein
CO703_RS03730	COG3539	Fimbrial protein
CO703_RS03745	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS03770	COG0730	response to heat
CO703_RS03775	COG3101	peptidyl-lysine hydroxylation
CO703_RS03790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CO703_RS03800	COG2814	Major facilitator Superfamily
CO703_RS03815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CO703_RS03825	COG0586	Pfam SNARE associated Golgi protein
CO703_RS03835	COG0285	dihydrofolate synthase activity
CO703_RS03840	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CO703_RS03845	COG1286	toxin biosynthetic process
CO703_RS03850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CO703_RS03855	COG0163	prenyltransferase activity
CO703_RS03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS03865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS03870	COG4215	(ABC) transporter
CO703_RS03875	COG4160	amino acid transport
CO703_RS03880	COG4598	ABC transporter
CO703_RS03885	COG5464	transposase or invertase
CO703_RS03890	COG1090	epimerase
CO703_RS03895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CO703_RS03900	COG0625	glutathione transferase activity
CO703_RS03905	COG0625	glutathione transferase activity
CO703_RS03910	COG0622	Phosphoesterase
CO703_RS03915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CO703_RS03920	COG1288	antiporter activity
CO703_RS03925	COG0857	belongs to the CobB CobQ family
CO703_RS03925	COG0280	phosphate acetyltransferase
CO703_RS03930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CO703_RS03945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO703_RS03950	COG0490	domain, Protein
CO703_RS03950	COG0471	metal ion transport
CO703_RS03960	COG0436	Aminotransferase
CO703_RS03970	COG0583	DNA-binding transcription factor activity
CO703_RS03990	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CO703_RS03995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CO703_RS04000	COG1034	ATP synthesis coupled electron transport
CO703_RS04015	COG0839	Belongs to the complex I subunit 6 family
CO703_RS04025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CO703_RS04030	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO703_RS04060	COG2153	protein acetylation
CO703_RS04065	COG4575	ribosome binding
CO703_RS04070	COG1169	isochorismate synthase
CO703_RS04085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CO703_RS04095	COG0318	PFAM AMP-dependent synthetase and ligase
CO703_RS04165	COG5464	transposase or invertase
CO703_RS04170	COG0247	lactate metabolic process
CO703_RS04180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CO703_RS04185	COG2271	Major facilitator Superfamily
CO703_RS04190	COG0584	glycerophosphoryl diester phosphodiesterase
CO703_RS04195	COG0583	DNA-binding transcription factor activity
CO703_RS04200	COG3039	Transposase
CO703_RS04210	COG3642	lipopolysaccharide core region biosynthetic process
CO703_RS04215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO703_RS04220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CO703_RS04225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CO703_RS04235	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS04245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CO703_RS04250	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CO703_RS04255	COG3234	Protein of unknown function (DUF1175)
CO703_RS04260	COG2373	Large extracellular alpha-helical protein
CO703_RS04265	COG5445	Predicted secreted protein (DUF2300)
CO703_RS04270	COG4676	Protein conserved in bacteria
CO703_RS04275	COG0784	Response regulator, receiver
CO703_RS04275	COG2205	protein histidine kinase activity
CO703_RS04280	COG2197	response regulator
CO703_RS04285	COG2198	Histidine kinase
CO703_RS04285	COG0642	Histidine kinase
CO703_RS04300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CO703_RS04305	COG1477	protein flavinylation
CO703_RS04310	COG2169	Transcriptional regulator
CO703_RS04310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CO703_RS04315	COG3145	DNA-N1-methyladenine dioxygenase activity
CO703_RS04320	COG4615	Cyclic peptide transporter
CO703_RS04340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS04340	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS04345	COG3062	negative regulation of establishment of protein localization
CO703_RS04355	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS04360	COG0348	domain, Protein
CO703_RS04365	COG3043	anaerobic respiration
CO703_RS04370	COG3005	denitrification pathway
CO703_RS04375	COG4133	protoheme IX ABC transporter activity
CO703_RS04380	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CO703_RS04385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CO703_RS04390	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CO703_RS04400	COG1138	Cytochrome C-type biogenesis protein
CO703_RS04405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CO703_RS04410	COG3088	subunit of a heme lyase
CO703_RS04410	COG4235	cytochrome complex assembly
CO703_RS04415	COG2197	response regulator
CO703_RS04425	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS04430	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS04445	COG3083	sulfuric ester hydrolase activity
CO703_RS04465	COG1061	Type III restriction enzyme res subunit
CO703_RS04475	COG1187	pseudouridine synthase activity
CO703_RS04480	COG2814	Major facilitator Superfamily
CO703_RS04495	COG4172	Belongs to the ABC transporter superfamily
CO703_RS04500	COG4239	(ABC) transporter, permease
CO703_RS04505	COG4174	ABC transporter (Permease)
CO703_RS04510	COG4166	transmembrane transport
CO703_RS04515	COG2200	EAL domain
CO703_RS04520	COG0791	NLP P60 protein
CO703_RS04525	COG0671	phosphoesterase, PA-phosphatase related
CO703_RS04530	COG0523	cobalamin synthesis protein
CO703_RS04535	COG0246	Mannitol dehydrogenase
CO703_RS04550	COG2814	Major facilitator Superfamily
CO703_RS04555	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS04555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS04560	COG1105	Belongs to the carbohydrate kinase PfkB family
CO703_RS04565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS04565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS04565	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CO703_RS04570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS04575	COG2313	pseudouridylate synthase activity
CO703_RS04580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CO703_RS04585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CO703_RS04595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CO703_RS04600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS04600	COG1522	sequence-specific DNA binding
CO703_RS04610	COG2855	membrane
CO703_RS04615	COG0583	DNA-binding transcription factor activity
CO703_RS04625	COG0833	amino acid
CO703_RS04635	COG4771	TonB-dependent receptor
CO703_RS04660	COG2311	Membrane
CO703_RS04670	COG1609	Transcriptional regulator
CO703_RS04675	COG1879	ABC-type sugar transport system periplasmic component
CO703_RS04680	COG1129	ABC transporter
CO703_RS04685	COG4211	Belongs to the binding-protein-dependent transport system permease family
CO703_RS04690	COG0167	dihydroorotate dehydrogenase activity
CO703_RS04690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CO703_RS04695	COG0493	'glutamate synthase
CO703_RS04705	COG2949	membrane
CO703_RS04715	COG1346	cytolysis
CO703_RS04725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CO703_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS04755	COG0586	Pfam SNARE associated Golgi protein
CO703_RS04765	COG1686	Belongs to the peptidase S11 family
CO703_RS04770	COG0277	FAD linked oxidase domain protein
CO703_RS04775	COG1472	Belongs to the glycosyl hydrolase 3 family
CO703_RS04780	COG1732	Glycine betaine
CO703_RS04785	COG1174	glycine betaine transport
CO703_RS04790	COG1125	glycine betaine transport
CO703_RS04795	COG1174	glycine betaine transport
CO703_RS04805	COG0789	Transcriptional regulator
CO703_RS04810	COG3275	phosphorelay sensor kinase activity
CO703_RS04815	COG3279	Response regulator of the LytR AlgR family
CO703_RS04820	COG4807	Protein conserved in bacteria
CO703_RS04825	COG4808	Protein conserved in bacteria
CO703_RS04830	COG4715	Zinc finger, swim domain protein
CO703_RS04835	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CO703_RS04840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CO703_RS04845	COG0714	Associated with various cellular activities
CO703_RS04855	COG3831	ATPase activity
CO703_RS04860	COG3831	ATPase activity
CO703_RS04870	COG0489	protein tyrosine kinase activity
CO703_RS04885	COG3539	Fimbrial protein
CO703_RS04890	COG3121	Chaperone
CO703_RS04895	COG3188	usher protein
CO703_RS04920	COG5455	response to cobalt ion
CO703_RS04940	COG0351	phosphomethylpyrimidine kinase
CO703_RS04945	COG3757	hydrolase, family 25
CO703_RS04950	COG2188	Transcriptional regulator
CO703_RS04955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS04960	COG1397	ADP-ribosylglycohydrolase
CO703_RS04965	COG2211	Major facilitator Superfamily
CO703_RS04970	COG1830	Aldolase
CO703_RS04990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS04995	COG3414	Phosphotransferase system galactitol-specific IIB component
CO703_RS05000	COG3775	system Galactitol-specific IIC component
CO703_RS05005	COG1063	alcohol dehydrogenase
CO703_RS05030	COG0826	peptidase U32
CO703_RS05040	COG3609	addiction module antidote protein, CC2985 family
CO703_RS05050	COG0745	RESPONSE REGULATOR receiver
CO703_RS05055	COG2205	protein histidine kinase activity
CO703_RS05085	COG4245	von Willebrand factor, type A
CO703_RS05090	COG0631	protein serine/threonine phosphatase activity
CO703_RS05095	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CO703_RS05100	COG0443	Heat shock 70 kDa protein
CO703_RS05105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CO703_RS05110	COG5001	Diguanylate cyclase
CO703_RS05110	COG5002	protein histidine kinase activity
CO703_RS05110	COG3447	MASE1 domain protein
CO703_RS05115	COG0572	uridine kinase
CO703_RS05125	COG2982	Protein involved in outer membrane biogenesis
CO703_RS05130	COG1253	flavin adenine dinucleotide binding
CO703_RS05135	COG1596	polysaccharide export
CO703_RS05140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CO703_RS05145	COG3206	protein involved in exopolysaccharide biosynthesis
CO703_RS05145	COG0489	protein tyrosine kinase activity
CO703_RS05150	COG0463	Glycosyl transferase, family 2
CO703_RS05155	COG1045	serine acetyltransferase
CO703_RS05160	COG0438	transferase activity, transferring glycosyl groups
CO703_RS05170	COG1216	Glycosyl transferase, family 2
CO703_RS05175	COG0110	maltose O-acetyltransferase activity
CO703_RS05180	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CO703_RS05185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO703_RS05190	COG1051	belongs to the nudix hydrolase family
CO703_RS05195	COG0297	glycogen (starch) synthase activity
CO703_RS05200	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CO703_RS05200	COG0662	Cupin 2, conserved barrel domain protein
CO703_RS05205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CO703_RS05210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CO703_RS05215	COG2244	polysaccharide biosynthetic process
CO703_RS05220	COG2327	Polysaccharide pyruvyl transferase
CO703_RS05225	COG0438	transferase activity, transferring glycosyl groups
CO703_RS05235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO703_RS05240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CO703_RS05255	COG2089	acid synthase
CO703_RS05295	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CO703_RS05300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CO703_RS05325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CO703_RS05330	COG0131	Imidazoleglycerol-phosphate dehydratase
CO703_RS05330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CO703_RS05340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CO703_RS05360	COG2161	toxin-antitoxin pair type II binding
CO703_RS05365	COG4115	mRNA cleavage
CO703_RS05370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO703_RS05375	COG0583	DNA-binding transcription factor activity
CO703_RS05380	COG0531	amino acid
CO703_RS05385	COG2391	methyltransferase activity
CO703_RS05390	COG0425	Belongs to the sulfur carrier protein TusA family
CO703_RS05395	COG2925	Exonuclease
CO703_RS05400	COG1686	Belongs to the peptidase S11 family
CO703_RS05410	COG1289	transmembrane transporter activity
CO703_RS05415	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS05460	COG2003	Belongs to the UPF0758 family
CO703_RS05540	COG3436	PFAM IS66 Orf2 family protein
CO703_RS05545	COG4372	Transposase
CO703_RS05610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CO703_RS05625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS05640	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CO703_RS05655	COG1376	ErfK ybiS ycfS ynhG family protein
CO703_RS05665	COG0583	DNA-binding transcription factor activity
CO703_RS05670	COG0583	DNA-binding transcription factor activity
CO703_RS05680	COG0534	Mate efflux family protein
CO703_RS05695	COG0217	transcriptional regulatory protein
CO703_RS05700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CO703_RS05705	COG0477	Major facilitator Superfamily
CO703_RS05715	COG1470	cell adhesion involved in biofilm formation
CO703_RS05715	COG1388	LysM domain
CO703_RS05720	COG1388	LysM domain
CO703_RS05720	COG1470	cell adhesion involved in biofilm formation
CO703_RS05725	COG1388	LysM domain
CO703_RS05725	COG1470	cell adhesion involved in biofilm formation
CO703_RS05730	COG1388	LysM domain
CO703_RS05730	COG2373	Large extracellular alpha-helical protein
CO703_RS05730	COG4932	domain protein
CO703_RS05735	COG4771	TonB-dependent receptor
CO703_RS05740	COG1021	2,3-dihydroxybenzoate-AMP ligase
CO703_RS05760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CO703_RS05760	COG3433	isochorismatase activity
CO703_RS05760	COG2226	methyltransferase
CO703_RS05775	COG1132	(ABC) transporter
CO703_RS05785	COG1169	isochorismate synthase
CO703_RS05790	COG0582	viral genome integration into host DNA
CO703_RS05815	COG3443	Belongs to the bacterial solute-binding protein 9 family
CO703_RS05830	COG2351	hydroxyisourate hydrolase activity
CO703_RS05835	COG0745	RESPONSE REGULATOR receiver
CO703_RS05840	COG2205	protein histidine kinase activity
CO703_RS05870	COG2826	transposase and inactivated derivatives, IS30 family
CO703_RS05890	COG1418	mRNA catabolic process
CO703_RS05895	COG0270	DNA (cytosine-5-)-methyltransferase activity
CO703_RS05900	COG3727	T/G mismatch-specific endonuclease activity
CO703_RS05905	COG0697	spore germination
CO703_RS05910	COG2354	Protein conserved in bacteria
CO703_RS05915	COG5475	Uncharacterized small protein (DUF2158)
CO703_RS05950	COG2197	response regulator
CO703_RS05955	COG1684	flagellar biosynthetic protein fliR
CO703_RS05960	COG1987	bacterial-type flagellum assembly
CO703_RS05965	COG1338	Plays a role in the flagellum-specific transport system
CO703_RS05970	COG3190	flagellar
CO703_RS05975	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CO703_RS05980	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CO703_RS05985	COG1580	Controls the rotational direction of flagella during chemotaxis
CO703_RS05990	COG3144	bacterial-type flagellum assembly
CO703_RS05995	COG2882	bacterial-type flagellum organization
CO703_RS06000	COG1157	protein secretion by the type III secretion system
CO703_RS06005	COG1317	bacterial-type flagellum organization
CO703_RS06010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CO703_RS06015	COG1766	The M ring may be actively involved in energy transduction
CO703_RS06035	COG2076	Multidrug Resistance protein
CO703_RS06040	COG1881	PFAM PEBP family protein
CO703_RS06045	COG2207	Transcriptional regulator
CO703_RS06060	COG2135	peptidase activity
CO703_RS06065	COG0425	Belongs to the sulfur carrier protein TusA family
CO703_RS06070	COG2391	methyltransferase activity
CO703_RS06085	COG0366	Alpha amylase catalytic
CO703_RS06095	COG1516	flagellar protein fliS
CO703_RS06100	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CO703_RS06105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CO703_RS06110	COG1191	sigma factor activity
CO703_RS06120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS06130	COG0765	amino acid transport
CO703_RS06135	COG1126	abc transporter atp-binding protein
CO703_RS06140	COG2197	response regulator
CO703_RS06155	COG2197	response regulator
CO703_RS06185	COG3318	Belongs to the UPF0149 family
CO703_RS06185	COG3012	SEC-C Motif Domain Protein
CO703_RS06190	COG0814	amino acid
CO703_RS06200	COG1528	Iron-storage protein
CO703_RS06225	COG1528	Iron-storage protein
CO703_RS06235	COG1879	ABC-type sugar transport system periplasmic component
CO703_RS06240	COG1129	ABC transporter
CO703_RS06245	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO703_RS06250	COG1877	trehalose-phosphatase activity
CO703_RS06260	COG0589	response to stress
CO703_RS06275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CO703_RS06280	COG1360	Flagellar Motor Protein
CO703_RS06285	COG2198	Histidine kinase
CO703_RS06285	COG0643	Histidine kinase
CO703_RS06290	COG0835	chemotaxis
CO703_RS06295	COG0840	transmembrane signaling receptor activity
CO703_RS06300	COG0840	transmembrane signaling receptor activity
CO703_RS06305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CO703_RS06310	COG2201	protein-glutamate methylesterase activity
CO703_RS06315	COG0745	RESPONSE REGULATOR receiver
CO703_RS06320	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CO703_RS06325	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CO703_RS06330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CO703_RS06340	COG3755	Protein conserved in bacteria
CO703_RS06355	COG3102	Protein conserved in bacteria
CO703_RS06365	COG3005	denitrification pathway
CO703_RS06370	COG0243	molybdopterin cofactor binding
CO703_RS06380	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS06395	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CO703_RS06400	COG1801	Protein of unknown function DUF72
CO703_RS06405	COG0582	viral genome integration into host DNA
CO703_RS06455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CO703_RS06460	COG5532	Uncharacterized conserved protein (DUF2303)
CO703_RS06500	COG3646	Phage regulatory protein
CO703_RS06510	COG1846	Transcriptional regulator
CO703_RS06520	COG4725	Belongs to the MT-A70-like family
CO703_RS06530	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CO703_RS06540	COG1403	HNH endonuclease
CO703_RS06570	COG2207	Transcriptional regulator
CO703_RS06620	COG3772	lysozyme
CO703_RS06640	COG4220	transposase activity
CO703_RS06710	COG1196	nuclear chromosome segregation
CO703_RS06745	COG5301	cellulose 1,4-beta-cellobiosidase activity
CO703_RS06750	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CO703_RS06770	COG1335	isochorismatase
CO703_RS06780	COG0494	nUDIX hydrolase
CO703_RS06785	COG0217	transcriptional regulatory protein
CO703_RS06815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CO703_RS06825	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CO703_RS06830	COG0739	heme binding
CO703_RS06835	COG1560	Kdo2-lipid A biosynthetic process
CO703_RS06840	COG0469	pyruvate kinase activity
CO703_RS06845	COG1737	Transcriptional regulator
CO703_RS06850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CO703_RS06855	COG0129	dihydroxy-acid dehydratase activity
CO703_RS06860	COG0800	Aldolase
CO703_RS06870	COG3141	response to X-ray
CO703_RS06880	COG2979	Protein of unknown function (DUF533)
CO703_RS06885	COG1770	oligopeptidase
CO703_RS06890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO703_RS06895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CO703_RS06905	COG2372	response to copper ion
CO703_RS06910	COG1276	copper resistance
CO703_RS06920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CO703_RS06940	COG3008	intermembrane lipid transfer
CO703_RS06945	COG2995	paraquat-inducible protein a
CO703_RS06950	COG1956	GAF domain-containing protein
CO703_RS06960	COG0793	Belongs to the peptidase S41A family
CO703_RS06970	COG2814	Major facilitator Superfamily
CO703_RS06975	COG1414	Transcriptional regulator
CO703_RS07010	COG2226	methyltransferase
CO703_RS07030	COG3716	PTS system mannose fructose sorbose family IID component
CO703_RS07035	COG3715	PTS system
CO703_RS07040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS07040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS07055	COG1253	flavin adenine dinucleotide binding
CO703_RS07060	COG2200	EAL domain
CO703_RS07065	COG1760	l-serine dehydratase
CO703_RS07075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CO703_RS07090	COG0251	oxidation-reduction process
CO703_RS07095	COG1199	ATP-dependent helicase activity
CO703_RS07100	COG1214	PFAM Peptidase M22, glycoprotease
CO703_RS07105	COG3065	identical protein binding
CO703_RS07110	COG0318	PFAM AMP-dependent synthetase and ligase
CO703_RS07115	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CO703_RS07120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO703_RS07125	COG4638	Rieske (2fe-2S)
CO703_RS07130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CO703_RS07135	COG0473	3-isopropylmalate dehydrogenase activity
CO703_RS07140	COG0583	DNA-binding transcription factor activity
CO703_RS07150	COG3615	Tellurite resistance protein tehB
CO703_RS07165	COG0675	Transposase, IS605 OrfB family
CO703_RS07170	COG2261	transglycosylase associated protein
CO703_RS07185	COG2199	diguanylate cyclase activity
CO703_RS07185	COG2203	Gaf domain
CO703_RS07190	COG3042	response to heat
CO703_RS07195	COG3189	MarR family transcriptional regulator
CO703_RS07200	COG2807	transmembrane transport
CO703_RS07205	COG2207	Transcriptional regulator
CO703_RS07220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CO703_RS07225	COG2199	diguanylate cyclase activity
CO703_RS07230	COG2199	diguanylate cyclase activity
CO703_RS07240	COG2766	serine protein kinase
CO703_RS07245	COG3713	MltA-interacting MipA family protein
CO703_RS07250	COG0656	L-ascorbic acid biosynthetic process
CO703_RS07255	COG0676	glucose-6-phosphate 1-epimerase activity
CO703_RS07260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CO703_RS07270	COG3139	Protein of unknown function (DUF1315)
CO703_RS07275	COG1063	alcohol dehydrogenase
CO703_RS07280	COG2271	Major facilitator Superfamily
CO703_RS07285	COG1063	alcohol dehydrogenase
CO703_RS07290	COG0191	fructose-bisphosphate aldolase activity
CO703_RS07295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS07300	COG0667	Aldo Keto reductase
CO703_RS07305	COG1349	DNA-binding transcription factor activity
CO703_RS07310	COG2814	Major facilitator Superfamily
CO703_RS07315	COG1335	isochorismatase
CO703_RS07320	COG0252	asparaginase activity
CO703_RS07325	COG0616	signal peptide processing
CO703_RS07335	COG0778	Nitroreductase
CO703_RS07350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CO703_RS07360	COG3039	Transposase
CO703_RS07370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CO703_RS07380	COG0494	nUDIX hydrolase
CO703_RS07385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CO703_RS07390	COG2897	thiosulfate sulfurtransferase activity
CO703_RS07395	COG4136	ATPase activity
CO703_RS07400	COG4135	transport system, permease component
CO703_RS07405	COG4134	Bacterial extracellular solute-binding protein
CO703_RS07410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CO703_RS07415	COG0398	Pfam SNARE associated Golgi protein
CO703_RS07425	COG0398	Pfam SNARE associated Golgi protein
CO703_RS07430	COG0708	Exodeoxyribonuclease III
CO703_RS07465	COG3678	ATP-independent chaperone mediated protein folding
CO703_RS07475	COG0322	excinuclease ABC activity
CO703_RS07485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO703_RS07495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO703_RS07500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO703_RS07505	COG1447	Phosphotransferase system cellobiose-specific component IIA
CO703_RS07510	COG1917	Cupin 2, conserved barrel domain protein
CO703_RS07510	COG2169	Transcriptional regulator
CO703_RS07515	COG1486	melibiose metabolic process
CO703_RS07525	COG0753	catalase activity
CO703_RS07545	COG1823	symporter activity
CO703_RS07550	COG1988	membrane-bound metal-dependent
CO703_RS07555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO703_RS07565	COG3001	Fructosamine kinase
CO703_RS07575	COG1105	Belongs to the carbohydrate kinase PfkB family
CO703_RS07580	COG3137	Salt-induced outer membrane protein
CO703_RS07690	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CO703_RS07695	COG5301	cellulose 1,4-beta-cellobiosidase activity
CO703_RS07780	COG4695	Portal protein
CO703_RS07865	COG4974	Belongs to the 'phage' integrase family
CO703_RS07880	COG0386	Belongs to the glutathione peroxidase family
CO703_RS07890	COG0791	NLP P60 protein
CO703_RS07895	COG2200	EAL domain
CO703_RS07905	COG4256	Hemin uptake protein
CO703_RS07910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CO703_RS07925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO703_RS07925	COG0574	Belongs to the PEP-utilizing enzyme family
CO703_RS07930	COG0318	PFAM AMP-dependent synthetase and ligase
CO703_RS07935	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CO703_RS07940	COG0644	oxidoreductase
CO703_RS07945	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CO703_RS07950	COG2086	electron transfer activity
CO703_RS07960	COG1917	Cupin 2, conserved barrel domain protein
CO703_RS07960	COG2207	Transcriptional regulator
CO703_RS07965	COG1960	acyl-CoA dehydrogenase activity
CO703_RS07970	COG4670	ketone body catabolic process
CO703_RS07985	COG2271	Major facilitator Superfamily
CO703_RS07990	COG0738	Major facilitator superfamily
CO703_RS08005	COG0628	permease
CO703_RS08015	COG0277	FAD linked oxidase domain protein
CO703_RS08015	COG0247	lactate metabolic process
CO703_RS08020	COG2050	protein possibly involved in aromatic compounds catabolism
CO703_RS08030	COG0316	Belongs to the HesB IscA family
CO703_RS08035	COG0719	Fe-S assembly protein
CO703_RS08040	COG0396	ATPase activity
CO703_RS08045	COG0719	Fe-S assembly protein
CO703_RS08060	COG1376	ErfK ybiS ycfS ynhG family protein
CO703_RS08065	COG4238	major outer membrane lipoprotein
CO703_RS08070	COG0469	pyruvate kinase activity
CO703_RS08080	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS08085	COG2414	aldehyde ferredoxin oxidoreductase
CO703_RS08095	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS08100	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CO703_RS08110	COG4529	Protein conserved in bacteria
CO703_RS08130	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS08140	COG0307	riboflavin synthase, alpha
CO703_RS08145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CO703_RS08150	COG2814	Major facilitator Superfamily
CO703_RS08155	COG0583	DNA-binding transcription factor activity
CO703_RS08175	COG2814	Major facilitator Superfamily
CO703_RS08180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CO703_RS08185	COG0791	NLP P60 protein
CO703_RS08190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CO703_RS08195	COG1201	RNA secondary structure unwinding
CO703_RS08205	COG0346	lactoylglutathione lyase activity
CO703_RS08210	COG1902	pentaerythritol trinitrate reductase activity
CO703_RS08215	COG1309	transcriptional regulator
CO703_RS08220	COG3313	Fe-S protein
CO703_RS08225	COG4989	oxidoreductase activity
CO703_RS08230	COG2032	superoxide dismutase activity
CO703_RS08235	COG1289	transmembrane transporter activity
CO703_RS08240	COG1566	PFAM secretion protein HlyD family protein
CO703_RS08255	COG3133	Outer membrane lipoprotein
CO703_RS08265	COG3895	Periplasmic Protein
CO703_RS08280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CO703_RS08285	COG0625	glutathione transferase activity
CO703_RS08290	COG3104	oligopeptide transport
CO703_RS08300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CO703_RS08310	COG4659	FMN binding
CO703_RS08355	COG0673	inositol 2-dehydrogenase activity
CO703_RS08365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CO703_RS08370	COG1263	PTS System
CO703_RS08370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS08375	COG1609	Transcriptional regulator
CO703_RS08380	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS08385	COG1309	transcriptional regulator
CO703_RS08390	COG3250	beta-galactosidase activity
CO703_RS08405	COG5339	Protein conserved in bacteria
CO703_RS08410	COG1482	cell wall glycoprotein biosynthetic process
CO703_RS08415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CO703_RS08415	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CO703_RS08420	COG0114	fumarate hydratase activity
CO703_RS08430	COG2205	protein histidine kinase activity
CO703_RS08435	COG0745	RESPONSE REGULATOR receiver
CO703_RS08440	COG3136	membrane protein required for alginate biosynthesis
CO703_RS08450	COG0531	amino acid
CO703_RS08465	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CO703_RS08470	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CO703_RS08475	COG0628	permease
CO703_RS08495	COG3591	Belongs to the peptidase S1B family
CO703_RS08515	COG2814	Major facilitator Superfamily
CO703_RS08520	COG0583	DNA-binding transcription factor activity
CO703_RS08525	COG1940	carbohydrate kinase activity
CO703_RS08530	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CO703_RS08540	COG3381	protein complex oligomerization
CO703_RS08545	COG3302	dmso reductase anchor subunit
CO703_RS08550	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS08555	COG0582	viral genome integration into host DNA
CO703_RS08585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO703_RS08660	COG1484	DNA-dependent DNA replication
CO703_RS08665	COG1846	Transcriptional regulator
CO703_RS08780	COG3772	lysozyme
CO703_RS08955	COG3561	AntA/AntB antirepressor
CO703_RS08960	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS08965	COG0243	molybdopterin cofactor binding
CO703_RS08970	COG0243	molybdopterin cofactor binding
CO703_RS08985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO703_RS09005	COG4948	Mandelate Racemase Muconate Lactonizing
CO703_RS09010	COG1063	alcohol dehydrogenase
CO703_RS09015	COG0477	Major facilitator Superfamily
CO703_RS09020	COG0246	Mannitol dehydrogenase
CO703_RS09030	COG1802	Transcriptional regulator
CO703_RS09035	COG4221	oxidoreductase activity
CO703_RS09045	COG0339	signal peptide processing
CO703_RS09055	COG1546	Belongs to the CinA family
CO703_RS09060	COG3111	PFAM Bacterial OB fold (BOF) protein
CO703_RS09065	COG3706	GGDEF domain
CO703_RS09075	COG2814	Major facilitator Superfamily
CO703_RS09080	COG0697	spore germination
CO703_RS09085	COG2188	Transcriptional regulator
CO703_RS09095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CO703_RS09100	COG1447	Phosphotransferase system cellobiose-specific component IIA
CO703_RS09110	COG2723	6-phospho-beta-galactosidase activity
CO703_RS09120	COG4977	sequence-specific DNA binding
CO703_RS09125	COG1846	Transcriptional regulator
CO703_RS09150	COG0583	DNA-binding transcription factor activity
CO703_RS09155	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS09160	COG2066	Belongs to the glutaminase family
CO703_RS09175	COG2199	diguanylate cyclase activity
CO703_RS09195	COG3781	membrane
CO703_RS09255	COG1396	sequence-specific DNA binding
CO703_RS09260	COG3550	peptidyl-serine autophosphorylation
CO703_RS09275	COG3539	Fimbrial protein
CO703_RS09285	COG3188	usher protein
CO703_RS09290	COG3539	Fimbrial protein
CO703_RS09295	COG3539	Fimbrial protein
CO703_RS09300	COG3539	Fimbrial protein
CO703_RS09305	COG0243	molybdopterin cofactor binding
CO703_RS09315	COG2207	Transcriptional regulator
CO703_RS09325	COG3039	Transposase
CO703_RS09335	COG0641	radical SAM
CO703_RS09340	COG4178	(ABC) transporter
CO703_RS09345	COG4771	TonB-dependent receptor
CO703_RS09350	COG0612	Peptidase, M16
CO703_RS09355	COG0076	glutamate decarboxylase activity
CO703_RS09360	COG0531	amino acid
CO703_RS09365	COG1649	PFAM Uncharacterised BCR, COG1649
CO703_RS09375	COG2202	Pas domain
CO703_RS09375	COG2200	EAL domain
CO703_RS09375	COG2199	diguanylate cyclase activity
CO703_RS09380	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CO703_RS09385	COG0747	negative chemotaxis
CO703_RS09390	COG0601	transmembrane transport
CO703_RS09395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO703_RS09400	COG0444	Belongs to the ABC transporter superfamily
CO703_RS09405	COG4608	Belongs to the ABC transporter superfamily
CO703_RS09410	COG1764	response to oxidative stress
CO703_RS09435	COG1064	alcohol dehydrogenase
CO703_RS09440	COG3093	addiction module antidote protein HigA
CO703_RS09445	COG2864	formate dehydrogenase
CO703_RS09450	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS09460	COG0697	spore germination
CO703_RS09465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CO703_RS09470	COG4886	Leucine-rich repeat (LRR) protein
CO703_RS09475	COG2223	nitrite transmembrane transporter activity
CO703_RS09480	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CO703_RS09485	COG1140	nitrate reductase beta subunit
CO703_RS09490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CO703_RS09495	COG2181	nitrate reductase activity
CO703_RS09500	COG0384	phenazine biosynthesis protein PhzF
CO703_RS09505	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CO703_RS09510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CO703_RS09530	COG3209	COG3209 Rhs family protein
CO703_RS09545	COG0625	glutathione transferase activity
CO703_RS09550	COG1113	amino acid transport
CO703_RS09555	COG3391	amine dehydrogenase activity
CO703_RS09570	COG4772	TonB-dependent receptor
CO703_RS09575	COG1802	Transcriptional regulator
CO703_RS09580	COG2130	NADP-dependent
CO703_RS09590	COG1247	-acetyltransferase
CO703_RS09595	COG3238	Protein conserved in bacteria
CO703_RS09630	COG1177	transmembrane transport
CO703_RS09635	COG1176	ABC-type spermidine putrescine transport system, permease component I
CO703_RS09640	COG3842	ATPase activity
CO703_RS09645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CO703_RS09650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CO703_RS09655	COG1598	PFAM Uncharacterised protein family UPF0150
CO703_RS09670	COG0826	peptidase U32
CO703_RS09675	COG1396	sequence-specific DNA binding
CO703_RS09680	COG3135	benzoate transporter
CO703_RS09685	COG0675	Transposase, IS605 OrfB family
CO703_RS09700	COG0500	methyltransferase
CO703_RS09705	COG1275	C4-dicarboxylate transporter malic acid transport protein
CO703_RS09710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CO703_RS09715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO703_RS09720	COG2841	Protein conserved in bacteria
CO703_RS09740	COG5383	Protein conserved in bacteria
CO703_RS09745	COG0583	DNA-binding transcription factor activity
CO703_RS09750	COG0840	transmembrane signaling receptor activity
CO703_RS09765	COG3038	cytochrome b561
CO703_RS09770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CO703_RS09775	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS09780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CO703_RS09785	COG1643	Atp-dependent helicase
CO703_RS09795	COG2453	phosphatase
CO703_RS09795	COG0671	phosphoesterase, PA-phosphatase related
CO703_RS09800	COG2267	carboxylic ester hydrolase activity
CO703_RS09805	COG4589	Belongs to the CDS family
CO703_RS09810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CO703_RS09820	COG0667	Aldo Keto reductase
CO703_RS09825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CO703_RS09830	COG3327	negative regulation of DNA-templated transcription, initiation
CO703_RS09835	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CO703_RS09840	COG0183	Belongs to the thiolase family
CO703_RS09845	COG2050	protein possibly involved in aromatic compounds catabolism
CO703_RS09850	COG1250	3-hydroxyacyl-CoA dehydrogenase
CO703_RS09855	COG1024	Enoyl-CoA hydratase
CO703_RS09860	COG1024	Enoyl-CoA hydratase
CO703_RS09865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO703_RS09870	COG2151	metal-sulfur cluster biosynthetic enzyme
CO703_RS09875	COG3396	Phenylacetate-CoA oxygenase
CO703_RS09880	COG3460	Phenylacetate-CoA oxygenase
CO703_RS09885	COG3396	Phenylacetate-CoA oxygenase
CO703_RS09890	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS09890	COG2030	dehydratase
CO703_RS09895	COG3733	amine oxidase
CO703_RS09900	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS09905	COG2207	Transcriptional regulator
CO703_RS09910	COG3784	Protein of unknown function (DUF1318)
CO703_RS09920	COG2911	Protein conserved in bacteria
CO703_RS09925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CO703_RS09930	COG3187	Heat shock protein
CO703_RS09935	COG3042	response to heat
CO703_RS09940	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CO703_RS09940	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CO703_RS09940	COG0674	pyruvate-flavodoxin oxidoreductase activity
CO703_RS09940	COG1013	pyruvate-flavodoxin oxidoreductase activity
CO703_RS09950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CO703_RS09955	COG0589	response to stress
CO703_RS09965	COG0513	Belongs to the DEAD box helicase family
CO703_RS09980	COG3706	GGDEF domain
CO703_RS09985	COG2840	Smr protein MutS2
CO703_RS09990	COG0583	DNA-binding transcription factor activity
CO703_RS09995	COG1473	amidohydrolase
CO703_RS10000	COG1473	amidohydrolase
CO703_RS10010	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CO703_RS10015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CO703_RS10020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CO703_RS10025	COG0589	response to stress
CO703_RS10030	COG3182	Iron-regulated membrane protein
CO703_RS10035	COG0668	transmembrane transport
CO703_RS10040	COG4166	transmembrane transport
CO703_RS10045	COG0583	DNA-binding transcription factor activity
CO703_RS10050	COG1073	alpha beta
CO703_RS10055	COG2866	Carboxypeptidase
CO703_RS10060	COG4948	Mandelate Racemase Muconate Lactonizing
CO703_RS10065	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CO703_RS10070	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CO703_RS10080	COG3106	COG3106 Predicted ATPase
CO703_RS10085	COG1609	Transcriptional regulator
CO703_RS10095	COG3842	ATPase activity
CO703_RS10100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO703_RS10105	COG1554	hydrolase, family 65, central catalytic
CO703_RS10110	COG0673	inositol 2-dehydrogenase activity
CO703_RS10115	COG1082	Xylose isomerase domain protein TIM barrel
CO703_RS10120	COG1063	alcohol dehydrogenase
CO703_RS10125	COG0395	ABC-type sugar transport system, permease component
CO703_RS10130	COG1175	transmembrane transport
CO703_RS10135	COG1653	transport
CO703_RS10140	COG0366	Alpha amylase catalytic
CO703_RS10145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CO703_RS10155	COG1983	PspC domain protein
CO703_RS10165	COG1842	Phage shock protein A
CO703_RS10170	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CO703_RS10175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CO703_RS10180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CO703_RS10185	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS10195	COG1396	sequence-specific DNA binding
CO703_RS10195	COG1917	Cupin 2, conserved barrel domain protein
CO703_RS10200	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CO703_RS10205	COG0174	glutamine synthetase
CO703_RS10210	COG0531	amino acid
CO703_RS10225	COG4166	transmembrane transport
CO703_RS10230	COG4168	peptide transport system, permease
CO703_RS10235	COG4171	peptide transport system, permease
CO703_RS10240	COG4172	Belongs to the ABC transporter superfamily
CO703_RS10245	COG4172	Belongs to the ABC transporter superfamily
CO703_RS10250	COG2852	Protein conserved in bacteria
CO703_RS10260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CO703_RS10265	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CO703_RS10265	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CO703_RS10280	COG5001	Diguanylate cyclase
CO703_RS10290	COG1349	DNA-binding transcription factor activity
CO703_RS10300	COG0023	Translation Initiation Factor
CO703_RS10310	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CO703_RS10315	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CO703_RS10320	COG0671	phosphoesterase, PA-phosphatase related
CO703_RS10330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CO703_RS10350	COG0583	DNA-binding transcription factor activity
CO703_RS10360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CO703_RS10375	COG0616	signal peptide processing
CO703_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS10385	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CO703_RS10390	COG1187	pseudouridine synthase activity
CO703_RS10395	COG0009	L-threonylcarbamoyladenylate synthase
CO703_RS10400	COG0613	PHP domain protein
CO703_RS10405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CO703_RS10410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CO703_RS10410	COG0512	Glutamine amidotransferase of anthranilate synthase
CO703_RS10415	COG0135	phosphoribosylanthranilate isomerase activity
CO703_RS10415	COG0134	indole-3-glycerol-phosphate synthase activity
CO703_RS10430	COG3729	General stress protein
CO703_RS10435	COG3685	Protein conserved in bacteria
CO703_RS10440	COG3685	Protein conserved in bacteria
CO703_RS10455	COG0500	methyltransferase
CO703_RS10465	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CO703_RS10470	COG5301	cellulose 1,4-beta-cellobiosidase activity
CO703_RS10580	COG4220	transposase activity
CO703_RS10630	COG3772	lysozyme
CO703_RS10690	COG0484	heat shock protein binding
CO703_RS10695	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CO703_RS10700	COG1403	HNH endonuclease
CO703_RS10720	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CO703_RS10730	COG1846	Transcriptional regulator
CO703_RS10785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO703_RS10795	COG0582	viral genome integration into host DNA
CO703_RS10800	COG3047	cAMP biosynthetic process
CO703_RS10820	COG1607	acyl-coa hydrolase
CO703_RS10825	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CO703_RS10830	COG2350	Protein conserved in bacteria
CO703_RS10835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CO703_RS10855	COG4608	Belongs to the ABC transporter superfamily
CO703_RS10860	COG0444	Belongs to the ABC transporter superfamily
CO703_RS10865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO703_RS10870	COG0601	transmembrane transport
CO703_RS10875	COG4166	transmembrane transport
CO703_RS10880	COG2095	MarC family integral membrane protein
CO703_RS10885	COG1454	alcohol dehydrogenase
CO703_RS10885	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS10895	COG1435	thymidine kinase activity
CO703_RS10905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CO703_RS10910	COG0745	RESPONSE REGULATOR receiver
CO703_RS10915	COG1752	Esterase of the alpha-beta hydrolase superfamily
CO703_RS10925	COG0788	formyltetrahydrofolate deformylase activity
CO703_RS10945	COG2181	nitrate reductase activity
CO703_RS10950	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CO703_RS10955	COG1140	nitrate reductase beta subunit
CO703_RS10960	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CO703_RS10965	COG2223	nitrite transmembrane transporter activity
CO703_RS10975	COG3850	Histidine kinase
CO703_RS10980	COG2197	response regulator
CO703_RS10985	COG4932	domain protein
CO703_RS10990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CO703_RS10995	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CO703_RS11000	COG4572	Cation transport regulator
CO703_RS11005	COG0387	Pfam Sodium calcium exchanger
CO703_RS11035	COG2912	Transglutaminase-like superfamily
CO703_RS11040	COG3094	Invasion gene expression up-regulator, SirB
CO703_RS11045	COG2890	protein-(glutamine-N5) methyltransferase activity
CO703_RS11070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CO703_RS11075	COG0659	secondary active sulfate transmembrane transporter activity
CO703_RS11090	COG0012	GTP binding
CO703_RS11105	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS11110	COG3284	Transcriptional regulator
CO703_RS11115	COG2376	Dihydroxyacetone kinase
CO703_RS11120	COG1461	Dihydroxyacetone kinase
CO703_RS11125	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CO703_RS11125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS11125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO703_RS11150	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CO703_RS11165	COG1619	proteins homologs of microcin C7 resistance protein MccF
CO703_RS11175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CO703_RS11185	COG2719	SpoVR family
CO703_RS11200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CO703_RS11205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CO703_RS11210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CO703_RS11230	COG0179	Fumarylacetoacetate (FAA) hydrolase
CO703_RS11260	COG2894	cell division
CO703_RS11320	COG2200	EAL domain
CO703_RS11345	COG2200	EAL domain
CO703_RS11350	COG0789	Transcriptional regulator
CO703_RS11355	COG5562	phage envelope protein
CO703_RS11365	COG0538	isocitrate dehydrogenase activity
CO703_RS11370	COG1187	pseudouridine synthase activity
CO703_RS11390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CO703_RS11400	COG2205	protein histidine kinase activity
CO703_RS11405	COG2850	peptidyl-arginine hydroxylation
CO703_RS11420	COG3842	ATPase activity
CO703_RS11430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CO703_RS11435	COG5301	cellulose 1,4-beta-cellobiosidase activity
CO703_RS11540	COG4220	transposase activity
CO703_RS11560	COG3772	lysozyme
CO703_RS11605	COG0484	heat shock protein binding
CO703_RS11610	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CO703_RS11615	COG1403	HNH endonuclease
CO703_RS11690	COG1846	Transcriptional regulator
CO703_RS11755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO703_RS11765	COG0582	viral genome integration into host DNA
CO703_RS11770	COG1177	transmembrane transport
CO703_RS11775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CO703_RS11785	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CO703_RS11790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CO703_RS11800	COG4591	ABC-type transport system involved in lipoprotein release permease component
CO703_RS11810	COG4591	ABC-type transport system involved in lipoprotein release permease component
CO703_RS11815	COG4763	Acyl-transferase
CO703_RS11820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CO703_RS11825	COG1388	LysM domain
CO703_RS11825	COG1376	ErfK ybiS ycfS ynhG family protein
CO703_RS11835	COG1309	transcriptional regulator
CO703_RS11840	COG3134	Outer membrane lipoprotein
CO703_RS11850	COG1252	NADH dehydrogenase
CO703_RS11870	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CO703_RS11875	COG5633	Lipoprotein
CO703_RS11880	COG0537	adenosine 5'-monophosphoramidase activity
CO703_RS11885	COG4773	Receptor
CO703_RS11890	COG1263	PTS System
CO703_RS11890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS11895	COG0084	hydrolase, TatD family'
CO703_RS11900	COG0470	DNA polymerase III
CO703_RS11910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CO703_RS11915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CO703_RS11920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CO703_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS11935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CO703_RS11955	COG1399	metal-binding, possibly nucleic acid-binding protein
CO703_RS11960	COG0424	maF-like protein
CO703_RS11965	COG0564	pseudouridine synthase activity
CO703_RS11975	COG1530	ribonuclease E activity
CO703_RS11980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CO703_RS11985	COG1256	bacterial-type flagellum assembly
CO703_RS11990	COG1705	Flagellar rod assembly protein muramidase FlgJ
CO703_RS11990	COG3951	Flagellar rod assembly protein muramidase FlgJ
CO703_RS12005	COG4786	Flagellar basal body rod
CO703_RS12010	COG4787	bacterial-type flagellum-dependent cell motility
CO703_RS12015	COG1749	Flagellar hook protein flgE
CO703_RS12020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CO703_RS12025	COG1558	bacterial-type flagellum-dependent cell motility
CO703_RS12030	COG1815	bacterial-type flagellum-dependent cell motility
CO703_RS12035	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CO703_RS12040	COG2747	anti-sigma28 factor FlgM
CO703_RS12045	COG3418	PFAM FlgN family protein
CO703_RS12050	COG0728	peptidoglycan biosynthetic process
CO703_RS12055	COG0673	inositol 2-dehydrogenase activity
CO703_RS12065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CO703_RS12075	COG2999	glutathione oxidoreductase activity
CO703_RS12110	COG3038	cytochrome b561
CO703_RS12115	COG2353	YceI-like domain
CO703_RS12125	COG1560	Kdo2-lipid A biosynthetic process
CO703_RS12140	COG5645	(Lipo)protein
CO703_RS12145	COG2943	transferase activity, transferring hexosyl groups
CO703_RS12170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CO703_RS12175	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CO703_RS12210	COG2197	response regulator
CO703_RS12225	COG1462	curli production assembly transport component CsgG
CO703_RS12235	COG3381	protein complex oligomerization
CO703_RS12285	COG2003	Belongs to the UPF0758 family
CO703_RS12315	COG3436	PFAM IS66 Orf2 family protein
CO703_RS12430	COG1358	cellular component organization or biogenesis
CO703_RS12460	COG4245	von Willebrand factor, type A
CO703_RS12465	COG4245	von Willebrand factor, type A
CO703_RS12515	COG0583	DNA-binding transcription factor activity
CO703_RS12525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CO703_RS12620	COG2994	toxin metabolic process
CO703_RS12645	COG3039	Transposase
CO703_RS12710	COG4771	TonB-dependent receptor
CO703_RS12725	COG3436	PFAM IS66 Orf2 family protein
CO703_RS12765	COG0582	viral genome integration into host DNA
CO703_RS12790	COG3706	GGDEF domain
CO703_RS12795	COG0457	Tetratricopeptide repeat
CO703_RS12800	COG1649	PFAM Uncharacterised BCR, COG1649
CO703_RS12800	COG0726	polysaccharide deacetylase
CO703_RS12805	COG1215	transferase activity, transferring glycosyl groups
CO703_RS12810	COG3658	cytochrome
CO703_RS12815	COG1702	phosphate starvation-inducible protein PhoH
CO703_RS12830	COG2822	iron ion transport
CO703_RS12850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CO703_RS12865	COG0506	proline dehydrogenase activity
CO703_RS12865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CO703_RS12865	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CO703_RS12870	COG1309	transcriptional regulator
CO703_RS12905	COG2233	PERMEase
CO703_RS12910	COG3729	General stress protein
CO703_RS12995	COG5301	cellulose 1,4-beta-cellobiosidase activity
CO703_RS12995	COG5301	cellulose 1,4-beta-cellobiosidase activity
CO703_RS13065	COG3772	lysozyme
CO703_RS13190	COG3646	Phage regulatory protein
CO703_RS13230	COG5532	Uncharacterized conserved protein (DUF2303)
CO703_RS13265	COG3561	AntA/AntB antirepressor
CO703_RS13270	COG3561	AntA/AntB antirepressor
CO703_RS13310	COG0582	viral genome integration into host DNA
CO703_RS13350	COG0243	molybdopterin cofactor binding
CO703_RS13355	COG3005	denitrification pathway
CO703_RS13360	COG0745	RESPONSE REGULATOR receiver
CO703_RS13365	COG1879	ABC-type sugar transport system periplasmic component
CO703_RS13370	COG0784	Response regulator, receiver
CO703_RS13370	COG2205	protein histidine kinase activity
CO703_RS13370	COG2198	Histidine kinase
CO703_RS13375	COG0348	domain, Protein
CO703_RS13395	COG1278	Cold shock
CO703_RS13400	COG1278	Cold shock
CO703_RS13420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO703_RS13425	COG1596	polysaccharide export
CO703_RS13430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CO703_RS13435	COG0489	protein tyrosine kinase activity
CO703_RS13435	COG3206	protein involved in exopolysaccharide biosynthesis
CO703_RS13450	COG1294	oxidase, subunit
CO703_RS13455	COG1271	oxidase subunit
CO703_RS13460	COG1773	rubredoxin
CO703_RS13465	COG1999	signal sequence binding
CO703_RS13470	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CO703_RS13475	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CO703_RS13480	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CO703_RS13485	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CO703_RS13495	COG0670	Belongs to the BI1 family
CO703_RS13500	COG2920	part of a sulfur-relay system
CO703_RS13505	COG1254	Belongs to the acylphosphatase family
CO703_RS13520	COG1832	CoA-binding protein
CO703_RS13535	COG0210	DNA helicase
CO703_RS13540	COG3304	Inner membrane component domain
CO703_RS13545	COG1289	transmembrane transporter activity
CO703_RS13550	COG3070	regulator of competence-specific genes
CO703_RS13565	COG2885	chlorophyll binding
CO703_RS13565	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CO703_RS13575	COG1067	ATP-dependent peptidase activity
CO703_RS13585	COG3130	regulation of translation
CO703_RS13590	COG3009	Protein conserved in bacteria
CO703_RS13595	COG3008	intermembrane lipid transfer
CO703_RS13595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CO703_RS13600	COG2995	paraquat-inducible protein a
CO703_RS13605	COG0488	(ABC) transporter
CO703_RS13615	COG3217	Mosc domain protein beta barrel domain protein
CO703_RS13615	COG0633	Ferredoxin
CO703_RS13630	COG3121	Chaperone
CO703_RS13635	COG3539	Fimbrial protein
CO703_RS13640	COG3539	Fimbrial protein
CO703_RS13645	COG3539	Fimbrial protein
CO703_RS13650	COG3188	usher protein
CO703_RS13655	COG3121	Chaperone
CO703_RS13660	COG3539	Fimbrial protein
CO703_RS13670	COG0431	NADPH-dependent FMN reductase
CO703_RS13675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CO703_RS13685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CO703_RS13695	COG0308	aminopeptidase N
CO703_RS13720	COG1448	Aminotransferase
CO703_RS13730	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS13735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CO703_RS13740	COG3108	Peptidase M15
CO703_RS13750	COG2989	Protein conserved in bacteria
CO703_RS13760	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CO703_RS13770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CO703_RS13780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CO703_RS13785	COG3173	Aminoglycoside phosphotransferase
CO703_RS13800	COG3214	Protein conserved in bacteria
CO703_RS13810	COG1132	(ABC) transporter
CO703_RS13815	COG0658	competence protein
CO703_RS13815	COG2333	competence protein COMEC
CO703_RS13825	COG0539	negative regulation of cytoplasmic translation
CO703_RS13835	COG0501	Belongs to the peptidase M48B family
CO703_RS13850	COG2323	membrane
CO703_RS13855	COG1944	ATP diphosphatase activity
CO703_RS13860	COG2116	formate transmembrane transporter activity
CO703_RS13865	COG1882	Formate acetyltransferase
CO703_RS13870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CO703_RS13875	COG2249	NAD(P)H dehydrogenase (quinone) activity
CO703_RS13880	COG0583	DNA-binding transcription factor activity
CO703_RS13885	COG0531	amino acid
CO703_RS13895	COG1335	isochorismatase
CO703_RS13900	COG3302	dmso reductase anchor subunit
CO703_RS13905	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS13910	COG0243	molybdopterin cofactor binding
CO703_RS13920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CO703_RS13935	COG1522	sequence-specific DNA binding
CO703_RS13945	COG0492	ferredoxin-NADP+ reductase activity
CO703_RS13950	COG4988	ABC transporter
CO703_RS13955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CO703_RS13980	COG0542	response to heat
CO703_RS13990	COG1278	Cold shock
CO703_RS14000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS14005	COG2990	Protein conserved in bacteria
CO703_RS14010	COG3593	DNA synthesis involved in DNA repair
CO703_RS14025	COG2431	L-lysine efflux transmembrane transporter activity
CO703_RS14035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CO703_RS14040	COG0028	Belongs to the TPP enzyme family
CO703_RS14045	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CO703_RS14050	COG0702	epimerase
CO703_RS14055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CO703_RS14060	COG3023	N-Acetylmuramoyl-L-alanine amidase
CO703_RS14075	COG1126	abc transporter atp-binding protein
CO703_RS14080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS14085	COG4215	(ABC) transporter
CO703_RS14090	COG4160	amino acid transport
CO703_RS14095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS14110	COG1177	transmembrane transport
CO703_RS14115	COG1176	ABC-type spermidine putrescine transport system, permease component I
CO703_RS14120	COG3842	ATPase activity
CO703_RS14125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CO703_RS14145	COG0778	Nitroreductase
CO703_RS14155	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CO703_RS14170	COG3226	Transcriptional regulator
CO703_RS14175	COG0738	Major facilitator superfamily
CO703_RS14180	COG0561	phosphatase activity
CO703_RS14190	COG2814	Major facilitator Superfamily
CO703_RS14195	COG0671	phosphoesterase, PA-phosphatase related
CO703_RS14200	COG1349	DNA-binding transcription factor activity
CO703_RS14205	COG1686	Belongs to the peptidase S11 family
CO703_RS14210	COG0625	glutathione transferase activity
CO703_RS14215	COG2133	pyrroloquinoline quinone binding
CO703_RS14230	COG2199	diguanylate cyclase activity
CO703_RS14235	COG2200	EAL domain
CO703_RS14260	COG1446	asparaginase
CO703_RS14265	COG0303	'Molybdopterin
CO703_RS14270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CO703_RS14275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CO703_RS14280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CO703_RS14285	COG1882	Formate acetyltransferase
CO703_RS14290	COG0561	phosphatase activity
CO703_RS14300	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS14310	COG0488	(ABC) transporter
CO703_RS14315	COG1376	ErfK ybiS ycfS ynhG family protein
CO703_RS14320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CO703_RS14325	COG1321	iron dependent repressor
CO703_RS14335	COG2194	sulfuric ester hydrolase activity
CO703_RS14340	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CO703_RS14345	COG5006	permease, DMT superfamily
CO703_RS14370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS14375	COG0765	amino acid transport
CO703_RS14380	COG1126	abc transporter atp-binding protein
CO703_RS14385	COG0668	transmembrane transport
CO703_RS14400	COG4774	siderophore transport
CO703_RS14410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CO703_RS14420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CO703_RS14425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CO703_RS14430	COG1199	ATP-dependent helicase activity
CO703_RS14440	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CO703_RS14445	COG0513	Belongs to the DEAD box helicase family
CO703_RS14450	COG1309	transcriptional regulator
CO703_RS14460	COG1131	(ABC) transporter
CO703_RS14465	COG0842	Transport permease protein
CO703_RS14470	COG0842	Transport permease protein
CO703_RS14480	COG3568	Endonuclease Exonuclease Phosphatase
CO703_RS14485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CO703_RS14490	COG0392	lysyltransferase activity
CO703_RS14495	COG0670	Belongs to the BI1 family
CO703_RS14505	COG0670	Belongs to the BI1 family
CO703_RS14510	COG0314	molybdopterin synthase activity
CO703_RS14515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CO703_RS14525	COG0521	Mo-molybdopterin cofactor biosynthetic process
CO703_RS14535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CO703_RS14545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CO703_RS14550	COG2226	methyltransferase
CO703_RS14565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CO703_RS14570	COG1881	PFAM PEBP family protein
CO703_RS14580	COG2199	diguanylate cyclase activity
CO703_RS14585	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CO703_RS14590	COG5301	cellulose 1,4-beta-cellobiosidase activity
CO703_RS14675	COG1030	water channel activity
CO703_RS14695	COG4220	transposase activity
CO703_RS14710	COG5562	phage envelope protein
CO703_RS14730	COG3772	lysozyme
CO703_RS14790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CO703_RS14795	COG2076	Multidrug Resistance protein
CO703_RS14900	COG0582	viral genome integration into host DNA
CO703_RS14905	COG4677	pectinesterase activity
CO703_RS14910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CO703_RS14915	COG0471	metal ion transport
CO703_RS14920	COG2828	Protein conserved in bacteria
CO703_RS14925	COG0583	DNA-binding transcription factor activity
CO703_RS14935	COG0561	phosphatase activity
CO703_RS14945	COG4149	molybdate abc transporter
CO703_RS14950	COG0725	ABC transporter, periplasmic molybdate-binding protein
CO703_RS14965	COG2005	Transcriptional regulator
CO703_RS14965	COG3585	molybdate ion transport
CO703_RS14970	COG1119	ATPase activity
CO703_RS14975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CO703_RS14980	COG1085	galactose-1-phosphate uridylyltransferase
CO703_RS14990	COG2017	converts alpha-aldose to the beta-anomer
CO703_RS15000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CO703_RS15015	COG1230	cation diffusion facilitator family transporter
CO703_RS15020	COG3201	nicotinamide mononucleotide transporter
CO703_RS15070	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CO703_RS15075	COG2885	chlorophyll binding
CO703_RS15085	COG3064	Membrane
CO703_RS15090	COG0848	biopolymer transport protein
CO703_RS15095	COG0811	peptide transport
CO703_RS15100	COG0824	Thioesterase
CO703_RS15105	COG3790	cyd operon protein YbgE
CO703_RS15110	COG4890	Cyd operon protein YbgT
CO703_RS15115	COG1294	oxidase, subunit
CO703_RS15120	COG1271	oxidase subunit
CO703_RS15130	COG0383	alpha-mannosidase activity
CO703_RS15135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS15135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS15135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS15140	COG2188	Transcriptional regulator
CO703_RS15150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CO703_RS15160	COG0508	dehydrogenase complex catalyzes the overall conversion of
CO703_RS15165	COG0567	Dehydrogenase, E1 component
CO703_RS15170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CO703_RS15175	COG1053	succinate dehydrogenase
CO703_RS15180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CO703_RS15185	COG2009	succinate dehydrogenase
CO703_RS15200	COG0372	Belongs to the citrate synthase family
CO703_RS15205	COG3539	Fimbrial protein
CO703_RS15225	COG3180	Ammonia monooxygenase
CO703_RS15240	COG1984	allophanate hydrolase subunit 2
CO703_RS15245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CO703_RS15250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CO703_RS15260	COG0415	Belongs to the DNA photolyase family
CO703_RS15265	COG3272	Protein of unknown function (DUF1722)
CO703_RS15295	COG3209	COG3209 Rhs family protein
CO703_RS15325	COG2205	protein histidine kinase activity
CO703_RS15330	COG0745	RESPONSE REGULATOR receiver
CO703_RS15340	COG1982	Orn Lys Arg decarboxylase major
CO703_RS15345	COG0531	amino acid
CO703_RS15350	COG0033	Phosphoglucomutase
CO703_RS15355	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CO703_RS15360	COG0596	Alpha beta hydrolase
CO703_RS15370	COG0716	FMN binding
CO703_RS15380	COG0735	belongs to the Fur family
CO703_RS15405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS15405	COG2190	(PTS) system
CO703_RS15405	COG1263	PTS System
CO703_RS15415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CO703_RS15420	COG1940	carbohydrate kinase activity
CO703_RS15420	COG1846	Transcriptional regulator
CO703_RS15425	COG0647	UMP catabolic process
CO703_RS15435	COG0367	asparagine synthase
CO703_RS15480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CO703_RS15490	COG1702	phosphate starvation-inducible protein PhoH
CO703_RS15500	COG4535	Mg2 and Co2 transporter CorC
CO703_RS15505	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CO703_RS15520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS15525	COG0765	amino acid transport
CO703_RS15530	COG0765	amino acid transport
CO703_RS15535	COG1126	abc transporter atp-binding protein
CO703_RS15545	COG0443	Heat shock 70 kDa protein
CO703_RS15550	COG2214	Heat shock protein DnaJ domain protein
CO703_RS15560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CO703_RS15565	COG2214	Heat shock protein DnaJ domain protein
CO703_RS15575	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CO703_RS15580	COG2888	peptidyl-tyrosine sulfation
CO703_RS15595	COG1466	dna polymerase III delta subunit
CO703_RS15605	COG0406	alpha-ribazole phosphatase activity
CO703_RS15610	COG0799	negative regulation of ribosome biogenesis
CO703_RS15620	COG0768	penicillin binding
CO703_RS15625	COG0772	Belongs to the SEDS family
CO703_RS15630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CO703_RS15635	COG1686	Belongs to the peptidase S11 family
CO703_RS15655	COG0583	DNA-binding transcription factor activity
CO703_RS15670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CO703_RS15675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CO703_RS15700	COG3069	C4-dicarboxylate transmembrane transporter activity
CO703_RS15705	COG4565	transcriptional regulatory protein
CO703_RS15710	COG3290	protein histidine kinase activity
CO703_RS15715	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CO703_RS15725	COG2301	Belongs to the HpcH HpaI aldolase family
CO703_RS15730	COG3051	citrate lyase alpha subunit
CO703_RS15745	COG0471	metal ion transport
CO703_RS15750	COG3719	Belongs to the RNase T2 family
CO703_RS15760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CO703_RS15770	COG1063	alcohol dehydrogenase
CO703_RS15775	COG0589	response to stress
CO703_RS15780	COG3634	alkyl hydroperoxide reductase activity
CO703_RS15790	COG0450	alkyl hydroperoxide reductase
CO703_RS15795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CO703_RS15800	COG0583	DNA-binding transcription factor activity
CO703_RS15805	COG3969	phosphoadenosine phosphosulfate
CO703_RS15810	COG1475	DNA binding
CO703_RS15815	COG0436	Aminotransferase
CO703_RS15820	COG0371	Dehydrogenase
CO703_RS15825	COG2879	small protein
CO703_RS15830	COG1966	Carbon starvation protein
CO703_RS15835	COG2050	protein possibly involved in aromatic compounds catabolism
CO703_RS15840	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS15845	COG1535	isochorismatase
CO703_RS15845	COG3433	isochorismatase activity
CO703_RS15850	COG1021	2,3-dihydroxybenzoate-AMP ligase
CO703_RS15855	COG1169	isochorismate synthase
CO703_RS15865	COG4592	Periplasmic binding protein
CO703_RS15875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO703_RS15880	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO703_RS15885	COG1120	ATPase activity
CO703_RS15890	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CO703_RS15895	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CO703_RS15895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CO703_RS15900	COG3251	PFAM MbtH domain protein
CO703_RS15905	COG2382	esterase
CO703_RS15915	COG4771	TonB-dependent receptor
CO703_RS15920	COG2977	Belongs to the P-Pant transferase superfamily
CO703_RS15925	COG3385	transposase activity
CO703_RS15940	COG3385	transposase activity
CO703_RS15970	COG2315	Protein conserved in bacteria
CO703_RS15975	COG0778	Nitroreductase
CO703_RS15980	COG0668	transmembrane transport
CO703_RS15985	COG1113	amino acid transport
CO703_RS15990	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO703_RS15995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS16000	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS16005	COG1538	Outer membrane efflux protein
CO703_RS16015	COG0745	RESPONSE REGULATOR receiver
CO703_RS16020	COG5002	protein histidine kinase activity
CO703_RS16030	COG3501	Rhs element vgr protein
CO703_RS16040	COG4104	PAAR repeat-containing protein
CO703_RS16040	COG3209	COG3209 Rhs family protein
CO703_RS16050	COG5433	transposase activity
CO703_RS16055	COG1215	transferase activity, transferring glycosyl groups
CO703_RS16060	COG4783	chaperone-mediated protein folding
CO703_RS16075	COG2207	Transcriptional regulator
CO703_RS16090	COG2197	response regulator
CO703_RS16095	COG3539	Fimbrial protein
CO703_RS16100	COG3539	Fimbrial protein
CO703_RS16105	COG3188	usher protein
CO703_RS16110	COG3121	Chaperone
CO703_RS16115	COG3539	Fimbrial protein
CO703_RS16125	COG2501	S4 domain
CO703_RS16130	COG1988	membrane-bound metal-dependent
CO703_RS16140	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CO703_RS16155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CO703_RS16160	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CO703_RS16165	COG0549	Belongs to the carbamate kinase family
CO703_RS16175	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CO703_RS16180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CO703_RS16185	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CO703_RS16190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CO703_RS16195	COG3257	ureidoglycine aminohydrolase activity
CO703_RS16200	COG1929	Belongs to the glycerate kinase type-1 family
CO703_RS16205	COG2233	PERMEase
CO703_RS16215	COG1953	Uracil, thiamine, allantoin
CO703_RS16220	COG2084	Dehydrogenase
CO703_RS16225	COG3622	Belongs to the hyi family
CO703_RS16230	COG3960	tartronate-semialdehyde synthase activity
CO703_RS16235	COG1414	Transcriptional regulator
CO703_RS16245	COG0583	DNA-binding transcription factor activity
CO703_RS16265	COG3209	COG3209 Rhs family protein
CO703_RS16275	COG3209	COG3209 Rhs family protein
CO703_RS16280	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CO703_RS16285	COG4181	ATPase activity
CO703_RS16290	COG2755	lipolytic protein G-D-S-L family
CO703_RS16295	COG0300	oxidoreductase activity
CO703_RS16300	COG3118	belongs to the thioredoxin family
CO703_RS16305	COG0390	transport system, permease component
CO703_RS16310	COG4619	ABC transporter
CO703_RS16315	COG0330	HflC and HflK could
CO703_RS16320	COG1585	Membrane protein implicated in regulation of membrane protease activity
CO703_RS16325	COG0789	Transcriptional regulator
CO703_RS16330	COG0531	amino acid
CO703_RS16335	COG2066	Belongs to the glutaminase family
CO703_RS16340	COG2217	Heavy metal translocating P-type atpase
CO703_RS16345	COG3093	addiction module antidote protein HigA
CO703_RS16355	COG3735	TraB family
CO703_RS16365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CO703_RS16370	COG0737	Belongs to the 5'-nucleotidase family
CO703_RS16380	COG2223	nitrite transmembrane transporter activity
CO703_RS16385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CO703_RS16385	COG4651	solute:proton antiporter activity
CO703_RS16390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS16430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CO703_RS16445	COG2832	Protein of unknown function (DUF454)
CO703_RS16450	COG3923	Primosomal replication protein n
CO703_RS16460	COG1196	nuclear chromosome segregation
CO703_RS16460	COG3264	Mechanosensitive ion channel
CO703_RS16470	COG1309	transcriptional regulator
CO703_RS16475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS16480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO703_RS16495	COG0110	maltose O-acetyltransferase activity
CO703_RS16505	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CO703_RS16510	COG5507	3-demethylubiquinone-9 3-methyltransferase
CO703_RS16520	COG3695	enzyme binding
CO703_RS16525	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CO703_RS16530	COG1946	Acyl-CoA thioesterase
CO703_RS16535	COG0004	ammonium transporteR
CO703_RS16540	COG0347	Belongs to the P(II) protein family
CO703_RS16545	COG1132	(ABC) transporter
CO703_RS16550	COG1132	(ABC) transporter
CO703_RS16555	COG1522	sequence-specific DNA binding
CO703_RS16565	COG4533	DNA binding
CO703_RS16575	COG0824	Thioesterase
CO703_RS16580	COG1555	photosystem II stabilization
CO703_RS16585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CO703_RS16590	COG0776	regulation of translation
CO703_RS16595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CO703_RS16620	COG0271	Belongs to the BolA IbaG family
CO703_RS16630	COG3056	Lipoprotein
CO703_RS16635	COG2223	nitrite transmembrane transporter activity
CO703_RS16640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CO703_RS16645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CO703_RS16650	COG1845	cytochrome c oxidase, subunit III
CO703_RS16655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CO703_RS16680	COG2814	Major facilitator Superfamily
CO703_RS16690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CO703_RS16695	COG0693	protein deglycase activity
CO703_RS16710	COG0142	geranyltranstransferase activity
CO703_RS16720	COG0667	Aldo Keto reductase
CO703_RS16725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CO703_RS16730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CO703_RS16745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CO703_RS16745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CO703_RS16760	COG3248	Nucleoside-binding outer membrane protein
CO703_RS16765	COG1403	HNH endonuclease
CO703_RS16770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CO703_RS16775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CO703_RS16780	COG1862	Preprotein translocase
CO703_RS16800	COG0366	Alpha amylase catalytic
CO703_RS16805	COG1113	amino acid transport
CO703_RS16810	COG1114	Component of the transport system for branched-chain amino acids
CO703_RS16815	COG5002	protein histidine kinase activity
CO703_RS16820	COG0745	RESPONSE REGULATOR receiver
CO703_RS16825	COG0420	3'-5' exonuclease activity
CO703_RS16830	COG0419	ATPase involved in DNA repair
CO703_RS16835	COG2814	Major facilitator Superfamily
CO703_RS16840	COG1940	carbohydrate kinase activity
CO703_RS16860	COG4126	flavin adenine dinucleotide binding
CO703_RS16885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CO703_RS16890	COG3706	GGDEF domain
CO703_RS16900	COG1785	Belongs to the alkaline phosphatase family
CO703_RS16915	COG1181	Belongs to the D-alanine--D-alanine ligase family
CO703_RS16935	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CO703_RS16945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CO703_RS16950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CO703_RS16955	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS16965	COG0113	porphobilinogen synthase activity
CO703_RS16970	COG2175	clavaminate synthase activity
CO703_RS16975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CO703_RS16985	COG4521	taurine ABC transporter
CO703_RS16995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CO703_RS17000	COG1215	transferase activity, transferring glycosyl groups
CO703_RS17030	COG3122	Protein conserved in bacteria
CO703_RS17035	COG2814	Major facilitator Superfamily
CO703_RS17070	COG1414	Transcriptional regulator
CO703_RS17075	COG1609	Transcriptional regulator
CO703_RS17085	COG3250	beta-galactosidase activity
CO703_RS17090	COG2223	nitrite transmembrane transporter activity
CO703_RS17095	COG0110	maltose O-acetyltransferase activity
CO703_RS17100	COG2807	transmembrane transport
CO703_RS17110	COG0288	reversible hydration of carbon dioxide
CO703_RS17115	COG0583	DNA-binding transcription factor activity
CO703_RS17120	COG0402	S-adenosylhomocysteine deaminase activity
CO703_RS17125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CO703_RS17130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CO703_RS17135	COG2079	MmgE PrpD family protein
CO703_RS17140	COG0372	Belongs to the citrate synthase family
CO703_RS17145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CO703_RS17150	COG3829	transcription factor binding
CO703_RS17160	COG1280	lysine exporter protein (LysE YggA)
CO703_RS17175	COG1064	alcohol dehydrogenase
CO703_RS17185	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO703_RS17190	COG1129	ABC transporter
CO703_RS17195	COG1879	ABC-type sugar transport system periplasmic component
CO703_RS17205	COG0402	S-adenosylhomocysteine deaminase activity
CO703_RS17210	COG0549	Belongs to the carbamate kinase family
CO703_RS17215	COG1304	FMN binding
CO703_RS17220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CO703_RS17230	COG0666	response to abiotic stimulus
CO703_RS17245	COG0583	DNA-binding transcription factor activity
CO703_RS17250	COG2771	luxR family
CO703_RS17250	COG2200	EAL domain
CO703_RS17260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CO703_RS17300	COG1556	Lactate utilization protein
CO703_RS17305	COG1139	Iron-sulfur cluster binding protein
CO703_RS17310	COG0247	lactate metabolic process
CO703_RS17315	COG2207	Transcriptional regulator
CO703_RS17320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CO703_RS17330	COG3059	membrane
CO703_RS17335	COG3039	Transposase
CO703_RS17340	COG3059	membrane
CO703_RS17345	COG3708	Transcriptional regulator
CO703_RS17345	COG2207	Transcriptional regulator
CO703_RS17350	COG1388	LysM domain
CO703_RS17405	COG3188	usher protein
CO703_RS17415	COG3121	Chaperone
CO703_RS17420	COG0727	PFAM Uncharacterised protein family (UPF0153)
CO703_RS17430	COG3477	response to acidic pH
CO703_RS17440	COG2080	2 iron, 2 sulfur cluster binding
CO703_RS17445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CO703_RS17450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CO703_RS17455	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CO703_RS17460	COG0583	DNA-binding transcription factor activity
CO703_RS17475	COG3039	Transposase
CO703_RS17575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CO703_RS17595	COG2195	Cleaves the N-terminal amino acid of tripeptides
CO703_RS17600	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CO703_RS17605	COG1690	Belongs to the RtcB family
CO703_RS17615	COG0454	-acetyltransferase
CO703_RS17645	COG0791	NLP P60 protein
CO703_RS17650	COG3077	Addiction module antitoxin, RelB DinJ family
CO703_RS17655	COG3041	Addiction module toxin RelE StbE family
CO703_RS17660	COG3034	peptidoglycan biosynthetic process
CO703_RS17665	COG0121	glutamine amidotransferase
CO703_RS17675	COG1960	acyl-CoA dehydrogenase activity
CO703_RS17685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CO703_RS17805	COG3157	Type VI secretion system effector, Hcp
CO703_RS17810	COG4104	PAAR repeat-containing protein
CO703_RS17830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CO703_RS17840	COG2226	methyltransferase
CO703_RS17850	COG1388	LysM domain
CO703_RS17850	COG0741	lytic transglycosylase activity
CO703_RS17855	COG2226	methyltransferase
CO703_RS17865	COG0583	DNA-binding transcription factor activity
CO703_RS17870	COG0656	L-ascorbic acid biosynthetic process
CO703_RS17905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CO703_RS17910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CO703_RS17915	COG2011	ABC-type metal ion transport system permease component
CO703_RS17920	COG1464	Belongs to the NlpA lipoprotein family
CO703_RS17930	COG1720	tRNA m6t6A37 methyltransferase activity
CO703_RS17945	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS17955	COG3015	lipoprotein NlpE involved in copper resistance
CO703_RS17960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CO703_RS17965	COG4681	YaeQ
CO703_RS17975	COG4568	rho-dependent transcription termination
CO703_RS17985	COG0346	lactoylglutathione lyase activity
CO703_RS17990	COG1982	Orn Lys Arg decarboxylase major
CO703_RS18000	COG0587	DNA-directed DNA polymerase activity
CO703_RS18025	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CO703_RS18030	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CO703_RS18040	COG0750	zinc metalloprotease
CO703_RS18045	COG0575	Belongs to the CDS family
CO703_RS18050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CO703_RS18055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CO703_RS18090	COG0024	Methionine aminopeptidase
CO703_RS18110	COG3835	regulator
CO703_RS18115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CO703_RS18135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CO703_RS18140	COG2860	membrane
CO703_RS18160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO703_RS18165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CO703_RS18170	COG1120	ATPase activity
CO703_RS18175	COG4774	siderophore transport
CO703_RS18180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CO703_RS18190	COG1643	Atp-dependent helicase
CO703_RS18195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CO703_RS18205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CO703_RS18215	COG0617	tRNA 3'-terminal CCA addition
CO703_RS18220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CO703_RS18225	COG3539	Fimbrial protein
CO703_RS18230	COG3121	Chaperone
CO703_RS18235	COG3188	usher protein
CO703_RS18240	COG3539	Fimbrial protein
CO703_RS18245	COG3539	Fimbrial protein
CO703_RS18250	COG3539	Fimbrial protein
CO703_RS18255	COG3539	Fimbrial protein
CO703_RS18270	COG5464	transposase or invertase
CO703_RS18290	COG0726	polysaccharide deacetylase
CO703_RS18295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS18300	COG0842	Transport permease protein
CO703_RS18305	COG1131	(ABC) transporter
CO703_RS18310	COG0288	reversible hydration of carbon dioxide
CO703_RS18315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CO703_RS18320	COG4993	Dehydrogenase
CO703_RS18325	COG2132	Multicopper oxidase
CO703_RS18350	COG1049	propionate catabolic process, 2-methylcitrate cycle
CO703_RS18360	COG3064	Membrane
CO703_RS18365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CO703_RS18370	COG0508	dehydrogenase complex catalyzes the overall conversion of
CO703_RS18375	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CO703_RS18385	COG2186	Transcriptional regulator
CO703_RS18390	COG1113	amino acid transport
CO703_RS18395	COG3725	Membrane protein required for beta-lactamase induction
CO703_RS18400	COG3023	N-Acetylmuramoyl-L-alanine amidase
CO703_RS18405	COG0157	Belongs to the NadC ModD family
CO703_RS18415	COG4969	Belongs to the N-Me-Phe pilin family
CO703_RS18420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CO703_RS18425	COG1459	type II secretion system
CO703_RS18435	COG0237	dephospho-CoA kinase activity
CO703_RS18450	COG0494	nUDIX hydrolase
CO703_RS18470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CO703_RS18475	COG0849	cell division
CO703_RS18480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CO703_RS18485	COG1181	Belongs to the D-alanine--D-alanine ligase family
CO703_RS18500	COG0772	Belongs to the SEDS family
CO703_RS18515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CO703_RS18520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CO703_RS18525	COG0768	penicillin binding
CO703_RS18530	COG3116	cell division
CO703_RS18550	COG1609	Transcriptional regulator
CO703_RS18560	COG0440	acetolactate synthase activity
CO703_RS18565	COG0028	Belongs to the TPP enzyme family
CO703_RS18570	COG0583	DNA-binding transcription factor activity
CO703_RS18585	COG0473	3-isopropylmalate dehydrogenase activity
CO703_RS18600	COG2814	Major facilitator Superfamily
CO703_RS18615	COG4143	(ABC) transporter
CO703_RS18620	COG1178	ABC-type Fe3 transport system permease component
CO703_RS18630	COG0586	Pfam SNARE associated Golgi protein
CO703_RS18635	COG4977	sequence-specific DNA binding
CO703_RS18655	COG0235	Class ii aldolase
CO703_RS18660	COG0417	DNA replication proofreading
CO703_RS18670	COG0564	pseudouridine synthase activity
CO703_RS18675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CO703_RS18680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CO703_RS18685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CO703_RS18710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CO703_RS18725	COG2271	Major facilitator Superfamily
CO703_RS18730	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CO703_RS18735	COG0644	oxidoreductase
CO703_RS18790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CO703_RS18795	COG0505	Belongs to the CarA family
CO703_RS18820	COG1047	Peptidyl-prolyl cis-trans
CO703_RS18835	COG0196	riboflavin kinase activity
CO703_RS18865	COG0583	DNA-binding transcription factor activity
CO703_RS18895	COG4735	regulation of single-species biofilm formation
CO703_RS18900	COG1584	GPR1 FUN34 yaaH family protein
CO703_RS18905	COG0521	Mo-molybdopterin cofactor biosynthetic process
CO703_RS18915	COG1115	amino acid carrier protein
CO703_RS18930	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CO703_RS18940	COG0527	aspartate kinase activity
CO703_RS18940	COG0460	homoserine dehydrogenase
CO703_RS18950	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CO703_RS18960	COG0745	RESPONSE REGULATOR receiver
CO703_RS18965	COG4452	Inner membrane protein CreD
CO703_RS18970	COG2205	protein histidine kinase activity
CO703_RS18975	COG0745	RESPONSE REGULATOR receiver
CO703_RS18980	COG3045	CreA protein
CO703_RS18985	COG2207	Transcriptional regulator
CO703_RS18985	COG3708	Transcriptional regulator
CO703_RS19005	COG0741	lytic transglycosylase activity
CO703_RS19015	COG0488	(ABC) transporter
CO703_RS19020	COG3172	ATPase kinase involved in NAD metabolism
CO703_RS19020	COG1056	cytidyltransferase-related domain
CO703_RS19025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CO703_RS19030	COG0560	Phosphoserine phosphatase
CO703_RS19035	COG3726	membrane protein affecting hemolysin expression
CO703_RS19065	COG1328	CTP reductase activity
CO703_RS19070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CO703_RS19075	COG0084	hydrolase, TatD family'
CO703_RS19080	COG4667	esterase of the alpha-beta hydrolase superfamily
CO703_RS19090	COG2823	Periplasmic or secreted lipoprotein
CO703_RS19100	COG1011	Hydrolase
CO703_RS19105	COG0456	acetyltransferase
CO703_RS19110	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CO703_RS19140	COG4114	ferric iron reductase
CO703_RS19145	COG2197	response regulator
CO703_RS19150	COG2197	response regulator
CO703_RS19155	COG2966	Psort location CytoplasmicMembrane, score
CO703_RS19170	COG1484	DNA-dependent DNA replication
CO703_RS19185	COG1063	alcohol dehydrogenase
CO703_RS19190	COG1802	Transcriptional regulator
CO703_RS19195	COG2271	Major facilitator Superfamily
CO703_RS19200	COG0840	transmembrane signaling receptor activity
CO703_RS19210	COG1966	Carbon starvation protein
CO703_RS19215	COG2879	small protein
CO703_RS19220	COG0523	cobalamin synthesis protein
CO703_RS19240	COG0732	type I restriction modification DNA specificity domain
CO703_RS19255	COG5457	Domain of unknown function (DUF1127)
CO703_RS19260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CO703_RS19270	COG2814	Major facilitator Superfamily
CO703_RS19275	COG2733	membrane
CO703_RS19280	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CO703_RS19285	COG1924	4 iron, 4 sulfur cluster binding
CO703_RS19300	COG0477	Major facilitator Superfamily
CO703_RS19315	COG3366	ferrous iron transmembrane transporter activity
CO703_RS19320	COG0700	Nucleoside recognition
CO703_RS19325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CO703_RS19330	COG0583	DNA-binding transcription factor activity
CO703_RS19350	COG2186	Transcriptional regulator
CO703_RS19360	COG0246	Mannitol dehydrogenase
CO703_RS19375	COG2610	gluconate transmembrane transporter activity
CO703_RS19465	COG3436	PFAM IS66 Orf2 family protein
CO703_RS19470	COG4372	Transposase
CO703_RS19505	COG1595	DNA-templated transcription, initiation
CO703_RS19510	COG3712	iron ion homeostasis
CO703_RS19515	COG4772	TonB-dependent receptor
CO703_RS19520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CO703_RS19525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO703_RS19530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CO703_RS19535	COG1120	ATPase activity
CO703_RS19540	COG2085	NADP oxidoreductase coenzyme F420-dependent
CO703_RS19550	COG3344	reverse transcriptase
CO703_RS19565	COG0726	polysaccharide deacetylase
CO703_RS19570	COG0297	glycogen (starch) synthase activity
CO703_RS19575	COG2990	Protein conserved in bacteria
CO703_RS19590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CO703_RS19615	COG0604	alcohol dehydrogenase
CO703_RS19625	COG3436	PFAM IS66 Orf2 family protein
CO703_RS19630	COG4372	Transposase
CO703_RS19650	COG0440	acetolactate synthase activity
CO703_RS19655	COG1349	DNA-binding transcription factor activity
CO703_RS19665	COG0738	Major facilitator superfamily
CO703_RS19680	COG3037	sugar-specific permease SgaT UlaA
CO703_RS19690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS19715	COG1289	transmembrane transporter activity
CO703_RS19725	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CO703_RS19730	COG2190	(PTS) system
CO703_RS19730	COG1263	PTS System
CO703_RS19730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS19735	COG1737	Transcriptional regulator
CO703_RS19750	COG3177	Filamentation induced by cAMP protein fic
CO703_RS19785	COG4227	nucleotidyltransferase activity
CO703_RS19805	COG1064	alcohol dehydrogenase
CO703_RS19810	COG3265	gluconokinase activity
CO703_RS19820	COG1063	alcohol dehydrogenase
CO703_RS19825	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS19830	COG2610	gluconate transmembrane transporter activity
CO703_RS19835	COG1609	Transcriptional regulator
CO703_RS19840	COG0433	COG0433 Predicted ATPase
CO703_RS19845	COG0795	lipopolysaccharide-transporting ATPase activity
CO703_RS19850	COG0795	lipopolysaccharide-transporting ATPase activity
CO703_RS19860	COG2927	DNA polymerase III (CHI subunit)
CO703_RS19865	COG0525	valine-tRNA ligase activity
CO703_RS19870	COG4269	membrane
CO703_RS19875	COG0456	acetyltransferase
CO703_RS19880	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CO703_RS19915	COG2731	YhcH YjgK YiaL family protein
CO703_RS19920	COG1309	transcriptional regulator
CO703_RS19925	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS19930	COG0251	oxidation-reduction process
CO703_RS19955	COG0251	oxidation-reduction process
CO703_RS19965	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS19970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CO703_RS19975	COG1609	Transcriptional regulator
CO703_RS19980	COG1263	PTS System
CO703_RS19980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS19985	COG0366	Alpha amylase catalytic
CO703_RS19995	COG1328	CTP reductase activity
CO703_RS20000	COG0602	queuosine metabolic process
CO703_RS20005	COG3783	Cytochrome b(562)
CO703_RS20010	COG0312	modulator of DNA gyrase
CO703_RS20020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CO703_RS20030	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO703_RS20035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO703_RS20040	COG1129	ABC transporter
CO703_RS20045	COG1879	ABC-type sugar transport system periplasmic component
CO703_RS20050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CO703_RS20055	COG2337	Toxic component of a toxin-antitoxin (TA) module
CO703_RS20060	COG2336	PFAM SpoVT AbrB
CO703_RS20065	COG2105	PFAM AIG2 family protein
CO703_RS20070	COG2911	Protein conserved in bacteria
CO703_RS20075	COG0729	surface antigen
CO703_RS20090	COG1253	flavin adenine dinucleotide binding
CO703_RS20100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CO703_RS20105	COG1218	3'(2'),5'-bisphosphate nucleotidase
CO703_RS20110	COG0737	Belongs to the 5'-nucleotidase family
CO703_RS20115	COG1733	regulation of RNA biosynthetic process
CO703_RS20120	COG0702	epimerase
CO703_RS20125	COG0697	spore germination
CO703_RS20135	COG1113	amino acid transport
CO703_RS20140	COG0545	Peptidyl-prolyl cis-trans isomerase
CO703_RS20150	COG3061	Opacity-associated protein A
CO703_RS20160	COG0675	Transposase, IS605 OrfB family
CO703_RS20190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CO703_RS20210	COG3477	response to acidic pH
CO703_RS20235	COG3414	Phosphotransferase system galactitol-specific IIB component
CO703_RS20240	COG3037	sugar-specific permease SgaT UlaA
CO703_RS20255	COG1073	alpha beta
CO703_RS20260	COG3650	response to hydrogen peroxide
CO703_RS20275	COG1960	acyl-CoA dehydrogenase activity
CO703_RS20280	COG0754	glutathionylspermidine amidase activity
CO703_RS20285	COG5463	Belongs to the UPF0441 family
CO703_RS20300	COG1842	Phage shock protein A
CO703_RS20305	COG3789	protein conserved in bacteria
CO703_RS20310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CO703_RS20315	COG0557	exoribonuclease II activity
CO703_RS20330	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CO703_RS20335	COG0330	HflC and HflK could
CO703_RS20340	COG0330	HflC and HflK could
CO703_RS20345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CO703_RS20365	COG0860	N-Acetylmuramoyl-L-alanine amidase
CO703_RS20370	COG0802	atpase or kinase
CO703_RS20375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CO703_RS20375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CO703_RS20380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CO703_RS20420	COG3264	Mechanosensitive ion channel
CO703_RS20420	COG1511	domain protein
CO703_RS20435	COG0531	amino acid
CO703_RS20445	COG1053	succinate dehydrogenase
CO703_RS20450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CO703_RS20465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CO703_RS20470	COG3040	lipid binding
CO703_RS20475	COG2076	Multidrug Resistance protein
CO703_RS20480	COG5510	response to toxic substance
CO703_RS20485	COG5510	response to toxic substance
CO703_RS20495	COG1509	lysine 2,3-aminomutase activity
CO703_RS20520	COG0531	amino acid
CO703_RS20525	COG3030	protein affecting phage T7 exclusion by the F plasmid
CO703_RS20530	COG1027	Aspartate ammonia-lyase
CO703_RS20535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CO703_RS20550	COG1309	transcriptional regulator
CO703_RS20560	COG0582	viral genome integration into host DNA
CO703_RS20600	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS20615	COG3436	PFAM IS66 Orf2 family protein
CO703_RS20665	COG3344	reverse transcriptase
CO703_RS20715	COG4372	Transposase
CO703_RS20720	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS20785	COG2003	Belongs to the UPF0758 family
CO703_RS20825	COG3710	Transcriptional regulator
CO703_RS20835	COG0531	amino acid
CO703_RS20840	COG1982	Orn Lys Arg decarboxylase major
CO703_RS20845	COG3104	oligopeptide transport
CO703_RS20850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CO703_RS20870	COG2388	GCN5-related N-acetyl-transferase
CO703_RS20875	COG3592	Divergent 4Fe-4S mono-cluster
CO703_RS20880	COG3290	protein histidine kinase activity
CO703_RS20885	COG4565	transcriptional regulatory protein
CO703_RS20895	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CO703_RS20900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CO703_RS20900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CO703_RS20905	COG3647	Membrane
CO703_RS20910	COG2211	Major facilitator Superfamily
CO703_RS20915	COG1486	melibiose metabolic process
CO703_RS20925	COG2169	Transcriptional regulator
CO703_RS20930	COG1982	Orn Lys Arg decarboxylase major
CO703_RS20935	COG2207	Transcriptional regulator
CO703_RS20940	COG0531	amino acid
CO703_RS20945	COG2194	sulfuric ester hydrolase activity
CO703_RS20950	COG0745	RESPONSE REGULATOR receiver
CO703_RS20955	COG0642	Histidine kinase
CO703_RS20965	COG0477	Major facilitator Superfamily
CO703_RS20985	COG2824	Alkylphosphonate utilization operon protein PhnA
CO703_RS20990	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CO703_RS21000	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CO703_RS21005	COG3639	organic phosphonate transmembrane transporter activity
CO703_RS21010	COG2188	Transcriptional regulator
CO703_RS21015	COG3624	Phosphonate C-P lyase system protein PhnG
CO703_RS21020	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CO703_RS21025	COG3626	phosphonate metabolism
CO703_RS21030	COG3627	carbon phosphorus lyase activity
CO703_RS21035	COG4107	phosphonate C-P lyase system protein PhnK
CO703_RS21040	COG4778	phosphonate C-P lyase system protein PhnL
CO703_RS21045	COG3454	Phosphonate metabolism
CO703_RS21050	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CO703_RS21055	COG0456	acetyltransferase
CO703_RS21060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CO703_RS21070	COG0698	ribose 5-phosphate isomerase
CO703_RS21075	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CO703_RS21085	COG1566	PFAM secretion protein HlyD family protein
CO703_RS21090	COG1289	transmembrane transporter activity
CO703_RS21105	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CO703_RS21110	COG1301	dicarboxylic acid transport
CO703_RS21120	COG4235	cytochrome complex assembly
CO703_RS21125	COG3088	subunit of a heme lyase
CO703_RS21130	COG1138	Cytochrome C-type biogenesis protein
CO703_RS21135	COG3301	Polysulphide reductase, NrfD
CO703_RS21140	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS21145	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CO703_RS21160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CO703_RS21165	COG3162	membrane
CO703_RS21175	COG1357	PFAM Pentapeptide repeats (8 copies)
CO703_RS21180	COG0025	NhaP-type Na H and K H
CO703_RS21185	COG2252	PERMEase
CO703_RS21205	COG0789	Transcriptional regulator
CO703_RS21210	COG2207	Transcriptional regulator
CO703_RS21215	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CO703_RS21230	COG0629	single-stranded DNA binding
CO703_RS21235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CO703_RS21240	COG2315	Protein conserved in bacteria
CO703_RS21245	COG0432	Pfam Uncharacterised protein family UPF0047
CO703_RS21250	COG3700	Belongs to the class B bacterial acid phosphatase family
CO703_RS21260	COG1448	Aminotransferase
CO703_RS21265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CO703_RS21270	COG0305	Participates in initiation and elongation during chromosome replication
CO703_RS21275	COG0604	alcohol dehydrogenase
CO703_RS21285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CO703_RS21300	COG0735	belongs to the Fur family
CO703_RS21305	COG3237	CsbD-like
CO703_RS21320	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CO703_RS21345	COG1357	PFAM Pentapeptide repeats (8 copies)
CO703_RS21365	COG3842	ATPase activity
CO703_RS21375	COG2182	Extracellular solute-binding protein
CO703_RS21380	COG1175	transmembrane transport
CO703_RS21385	COG3833	ABC-type maltose transport systems, permease component
CO703_RS21390	COG0477	Major facilitator Superfamily
CO703_RS21390	COG2814	Major facilitator Superfamily
CO703_RS21405	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO703_RS21440	COG0527	aspartate kinase activity
CO703_RS21445	COG0542	response to heat
CO703_RS21450	COG3541	Predicted nucleotidyltransferase
CO703_RS21465	COG1187	pseudouridine synthase activity
CO703_RS21475	COG1283	sodium-dependent phosphate transmembrane transporter activity
CO703_RS21480	COG1410	methionine synthase
CO703_RS21480	COG0646	methionine synthase
CO703_RS21485	COG1414	Transcriptional regulator
CO703_RS21500	COG2224	Isocitrate lyase
CO703_RS21505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CO703_RS21515	COG0456	acetyltransferase
CO703_RS21550	COG0151	Belongs to the GarS family
CO703_RS21555	COG2204	response regulator
CO703_RS21560	COG4191	Histidine kinase
CO703_RS21570	COG3678	ATP-independent chaperone mediated protein folding
CO703_RS21585	COG3068	Protein conserved in bacteria
CO703_RS21620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CO703_RS21625	COG2104	thiamine diphosphate biosynthetic process
CO703_RS21635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CO703_RS21680	COG0250	Participates in transcription elongation, termination and antitermination
CO703_RS21685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CO703_RS21730	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CO703_RS21730	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CO703_RS21800	COG0583	DNA-binding transcription factor activity
CO703_RS21805	COG2271	Major facilitator Superfamily
CO703_RS21810	COG4948	Mandelate Racemase Muconate Lactonizing
CO703_RS21830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CO703_RS21845	COG2194	sulfuric ester hydrolase activity
CO703_RS21850	COG2207	Transcriptional regulator
CO703_RS21855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS21860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CO703_RS21865	COG1882	Formate acetyltransferase
CO703_RS21870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS21875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS21880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS21880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS21880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CO703_RS21885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CO703_RS21890	COG0371	Dehydrogenase
CO703_RS21895	COG3738	Protein conserved in bacteria
CO703_RS21900	COG0697	spore germination
CO703_RS21910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CO703_RS21915	COG0460	homoserine dehydrogenase
CO703_RS21915	COG0527	aspartate kinase activity
CO703_RS21920	COG0626	cystathionine gamma-synthase activity
CO703_RS21950	COG3209	COG3209 Rhs family protein
CO703_RS21960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CO703_RS21965	COG1609	Transcriptional regulator
CO703_RS21970	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CO703_RS21985	COG1575	Belongs to the MenA family. Type 1 subfamily
CO703_RS22000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CO703_RS22010	COG1494	fructose-1,6-bisphosphatase
CO703_RS22020	COG0589	response to stress
CO703_RS22025	COG3691	Protein conserved in bacteria
CO703_RS22030	COG3152	Membrane
CO703_RS22055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CO703_RS22070	COG3678	ATP-independent chaperone mediated protein folding
CO703_RS22075	COG0745	RESPONSE REGULATOR receiver
CO703_RS22080	COG2205	protein histidine kinase activity
CO703_RS22085	COG2258	MOSC domain
CO703_RS22100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CO703_RS22140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS22145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS22145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CO703_RS22150	COG1363	Peptidase, m42
CO703_RS22155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS22155	COG3711	transcriptional antiterminator
CO703_RS22175	COG0243	molybdopterin cofactor binding
CO703_RS22175	COG3383	formate dehydrogenase (NAD+) activity
CO703_RS22180	COG3383	formate dehydrogenase (NAD+) activity
CO703_RS22180	COG0243	molybdopterin cofactor binding
CO703_RS22185	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS22190	COG2864	formate dehydrogenase
CO703_RS22200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CO703_RS22205	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CO703_RS22220	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CO703_RS22230	COG0456	acetyltransferase
CO703_RS22245	COG1011	Hydrolase
CO703_RS22255	COG0477	Major facilitator Superfamily
CO703_RS22265	COG1063	alcohol dehydrogenase
CO703_RS22270	COG3684	Belongs to the aldolase LacD family
CO703_RS22275	COG2084	Dehydrogenase
CO703_RS22280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS22285	COG1349	DNA-binding transcription factor activity
CO703_RS22290	COG2271	Major facilitator Superfamily
CO703_RS22295	COG1082	Xylose isomerase domain protein TIM barrel
CO703_RS22300	COG2188	Transcriptional regulator
CO703_RS22305	COG1217	gtp-binding protein TYPA
CO703_RS22315	COG0174	glutamine synthetase
CO703_RS22320	COG3852	Histidine kinase
CO703_RS22325	COG2204	response regulator
CO703_RS22335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CO703_RS22355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CO703_RS22355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CO703_RS22365	COG0204	Acyl-transferase
CO703_RS22370	COG5339	Protein conserved in bacteria
CO703_RS22375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CO703_RS22380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CO703_RS22385	COG3084	Protein conserved in bacteria
CO703_RS22390	COG0746	molybdenum cofactor guanylyltransferase activity
CO703_RS22395	COG1763	Mo-molybdopterin cofactor biosynthetic process
CO703_RS22425	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CO703_RS22430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CO703_RS22435	COG1739	Uncharacterized protein family UPF0029
CO703_RS22455	COG0543	2 iron, 2 sulfur cluster binding
CO703_RS22460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CO703_RS22465	COG0250	Participates in transcription elongation, termination and antitermination
CO703_RS22475	COG0805	protein transport
CO703_RS22480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CO703_RS22485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CO703_RS22495	COG3165	ubiquinone biosynthetic process from chorismate
CO703_RS22505	COG1322	Protein conserved in bacteria
CO703_RS22510	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CO703_RS22515	COG0412	Dienelactone hydrolase
CO703_RS22525	COG0583	DNA-binding transcription factor activity
CO703_RS22530	COG0697	spore germination
CO703_RS22535	COG0561	phosphatase activity
CO703_RS22540	COG2267	carboxylic ester hydrolase activity
CO703_RS22545	COG1280	lysine exporter protein (LysE YggA)
CO703_RS22550	COG1280	lysine exporter protein (LysE YggA)
CO703_RS22555	COG0514	ATP-dependent DNA helicase (RecQ)
CO703_RS22560	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CO703_RS22565	COG2050	protein possibly involved in aromatic compounds catabolism
CO703_RS22570	COG2962	Rard protein
CO703_RS22600	COG0598	Magnesium transport protein CorA
CO703_RS22605	COG3698	Phosphodiester glycosidase
CO703_RS22610	COG0210	DNA helicase
CO703_RS22615	COG1011	Hydrolase
CO703_RS22625	COG3159	Protein conserved in bacteria
CO703_RS22635	COG5567	small periplasmic lipoprotein
CO703_RS22660	COG3072	Adenylate cyclase
CO703_RS22675	COG1587	Uroporphyrinogen-III synthase
CO703_RS22680	COG2959	enzyme of heme biosynthesis
CO703_RS22685	COG3071	HemY protein
CO703_RS22690	COG0641	radical SAM
CO703_RS22715	COG1113	amino acid transport
CO703_RS22735	COG2244	polysaccharide biosynthetic process
CO703_RS22740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CO703_RS22745	COG0456	acetyltransferase
CO703_RS22750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CO703_RS22755	COG1088	dTDP-glucose 4,6-dehydratase activity
CO703_RS22760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CO703_RS22765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CO703_RS22770	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CO703_RS22775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CO703_RS22785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CO703_RS22795	COG3118	belongs to the thioredoxin family
CO703_RS22815	COG0210	DNA helicase
CO703_RS22820	COG3692	DNA binding
CO703_RS22825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CO703_RS22835	COG0583	DNA-binding transcription factor activity
CO703_RS22840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CO703_RS22850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CO703_RS22855	COG3978	acetolactate synthase activity
CO703_RS22875	COG0606	chelatase, subunit chli
CO703_RS22880	COG3085	chromosome segregation
CO703_RS22920	COG2186	Transcriptional regulator
CO703_RS22925	COG0477	Major facilitator Superfamily
CO703_RS22930	COG1609	Transcriptional regulator
CO703_RS22935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS22940	COG1879	ABC-type sugar transport system periplasmic component
CO703_RS22945	COG1172	Belongs to the binding-protein-dependent transport system permease family
CO703_RS22950	COG1129	ABC transporter
CO703_RS22980	COG1522	sequence-specific DNA binding
CO703_RS22985	COG0716	FMN binding
CO703_RS23000	COG3312	ion transport
CO703_RS23055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CO703_RS23070	COG3188	usher protein
CO703_RS23080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CO703_RS23085	COG0573	inorganic phosphate transmembrane transporter activity
CO703_RS23090	COG0581	inorganic phosphate transmembrane transporter activity
CO703_RS23095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CO703_RS23100	COG0704	Plays a role in the regulation of phosphate uptake
CO703_RS23110	COG2190	(PTS) system
CO703_RS23110	COG1263	PTS System
CO703_RS23110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS23115	COG2723	6-phospho-beta-galactosidase activity
CO703_RS23125	COG2382	esterase
CO703_RS23130	COG0363	glucosamine-6-phosphate deaminase activity
CO703_RS23135	COG3196	Protein conserved in bacteria
CO703_RS23145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CO703_RS23150	COG2252	PERMEase
CO703_RS23155	COG0431	NADPH-dependent FMN reductase
CO703_RS23160	COG2091	lysine biosynthetic process via aminoadipic acid
CO703_RS23175	COG0814	amino acid
CO703_RS23225	COG0592	DNA-directed DNA polymerase activity
CO703_RS23235	COG0187	DNA topoisomerase II activity
CO703_RS23240	COG3753	Protein conserved in bacteria
CO703_RS23245	COG0561	phosphatase activity
CO703_RS23255	COG2186	Transcriptional regulator
CO703_RS23260	COG3734	2-keto-3-deoxy-galactonokinase
CO703_RS23265	COG0800	Aldolase
CO703_RS23275	COG2271	Major facilitator Superfamily
CO703_RS23285	COG0823	Involved in the tonB-independent uptake of proteins
CO703_RS23290	COG5645	(Lipo)protein
CO703_RS23310	COG2188	Transcriptional regulator
CO703_RS23325	COG2207	Transcriptional regulator
CO703_RS23340	COG2207	Transcriptional regulator
CO703_RS23345	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CO703_RS23350	COG3119	arylsulfatase activity
CO703_RS23360	COG2149	membrane
CO703_RS23370	COG0641	radical SAM
CO703_RS23375	COG2814	Major facilitator Superfamily
CO703_RS23410	COG0028	Belongs to the TPP enzyme family
CO703_RS23415	COG0440	acetolactate synthase activity
CO703_RS23420	COG2197	response regulator
CO703_RS23425	COG3851	Histidine kinase
CO703_RS23430	COG2271	Major facilitator Superfamily
CO703_RS23435	COG2271	Major facilitator Superfamily
CO703_RS23445	COG2252	PERMEase
CO703_RS23475	COG1464	Belongs to the NlpA lipoprotein family
CO703_RS23480	COG0697	spore germination
CO703_RS23485	COG2814	Major facilitator Superfamily
CO703_RS23530	COG2003	Belongs to the UPF0758 family
CO703_RS23560	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS23795	COG0582	viral genome integration into host DNA
CO703_RS23805	COG2211	Major facilitator Superfamily
CO703_RS23810	COG1501	Belongs to the glycosyl hydrolase 31 family
CO703_RS23815	COG2982	Protein involved in outer membrane biogenesis
CO703_RS23820	COG2233	PERMEase
CO703_RS23825	COG0786	glutamate:sodium symporter activity
CO703_RS23830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CO703_RS23835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CO703_RS23840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CO703_RS23850	COG0194	GDP metabolic process
CO703_RS23860	COG2860	membrane
CO703_RS23865	COG3645	SOS response
CO703_RS23870	COG1561	YicC-like family, N-terminal region
CO703_RS23900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CO703_RS23930	COG1519	Transferase
CO703_RS23935	COG0859	PFAM glycosyl transferase family 9
CO703_RS23940	COG0438	transferase activity, transferring glycosyl groups
CO703_RS23945	COG0515	serine threonine protein kinase
CO703_RS23955	COG3642	lipopolysaccharide core region biosynthetic process
CO703_RS23975	COG0859	PFAM glycosyl transferase family 9
CO703_RS23980	COG0859	PFAM glycosyl transferase family 9
CO703_RS23995	COG0156	8-amino-7-oxononanoate synthase activity
CO703_RS24005	COG1216	Glycosyl transferase, family 2
CO703_RS24010	COG2861	carbohydrate metabolic process
CO703_RS24015	COG4942	peptidase
CO703_RS24030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CO703_RS24035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CO703_RS24050	COG1045	serine acetyltransferase
CO703_RS24055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CO703_RS24065	COG2186	Transcriptional regulator
CO703_RS24070	COG1620	l-lactate permease
CO703_RS24075	COG5295	Hep Hag repeat protein
CO703_RS24100	COG3722	fumarate hydratase activity
CO703_RS24110	COG2213	PTS system mannitol-specific
CO703_RS24110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS24120	COG1566	PFAM secretion protein HlyD family protein
CO703_RS24140	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CO703_RS24145	COG3209	COG3209 Rhs family protein
CO703_RS24150	COG1413	lyase activity
CO703_RS24165	COG3209	COG3209 Rhs family protein
CO703_RS24170	COG0625	glutathione transferase activity
CO703_RS24180	COG3276	selenocysteine insertion sequence binding
CO703_RS24185	COG1454	alcohol dehydrogenase
CO703_RS24190	COG1012	belongs to the aldehyde dehydrogenase family
CO703_RS24205	COG1566	PFAM secretion protein HlyD family protein
CO703_RS24210	COG0583	DNA-binding transcription factor activity
CO703_RS24215	COG3713	MltA-interacting MipA family protein
CO703_RS24225	COG0235	Class ii aldolase
CO703_RS24250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CO703_RS24255	COG2731	YhcH YjgK YiaL family protein
CO703_RS24265	COG1414	Transcriptional regulator
CO703_RS24270	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CO703_RS24275	COG3977	Valine--pyruvate aminotransferase
CO703_RS24285	COG2992	FlgJ-related protein
CO703_RS24290	COG1609	Transcriptional regulator
CO703_RS24290	COG2207	Transcriptional regulator
CO703_RS24295	COG4214	carbohydrate transport
CO703_RS24300	COG1129	ABC transporter
CO703_RS24305	COG4213	ABC transporter substrate-binding protein
CO703_RS24315	COG1070	Carbohydrate kinase
CO703_RS24320	COG4682	membrane
CO703_RS24325	COG4682	membrane
CO703_RS24330	COG3274	enterobacterial common antigen metabolic process
CO703_RS24355	COG1278	Cold shock
CO703_RS24360	COG2944	sequence-specific DNA binding
CO703_RS24375	COG2885	chlorophyll binding
CO703_RS24380	COG0243	molybdopterin cofactor binding
CO703_RS24385	COG0456	acetyltransferase
CO703_RS24390	COG2818	Glycosylase
CO703_RS24395	COG5571	outer membrane autotransporter
CO703_RS24405	COG2223	nitrite transmembrane transporter activity
CO703_RS24435	COG2194	sulfuric ester hydrolase activity
CO703_RS24445	COG0747	negative chemotaxis
CO703_RS24455	COG0601	transmembrane transport
CO703_RS24460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO703_RS24465	COG0444	Belongs to the ABC transporter superfamily
CO703_RS24470	COG4608	Belongs to the ABC transporter superfamily
CO703_RS24475	COG0814	amino acid
CO703_RS24520	COG2194	sulfuric ester hydrolase activity
CO703_RS24545	COG1215	transferase activity, transferring glycosyl groups
CO703_RS24550	COG1215	transferase activity, transferring glycosyl groups
CO703_RS24555	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CO703_RS24560	COG0457	Tetratricopeptide repeat
CO703_RS24560	COG3118	belongs to the thioredoxin family
CO703_RS24565	COG2199	diguanylate cyclase activity
CO703_RS24565	COG2200	EAL domain
CO703_RS24585	COG0612	Peptidase, M16
CO703_RS24600	COG2200	EAL domain
CO703_RS24605	COG2982	Protein involved in outer membrane biogenesis
CO703_RS24610	COG0477	Major facilitator Superfamily
CO703_RS24615	COG1295	ribonuclease BN
CO703_RS24620	COG0583	DNA-binding transcription factor activity
CO703_RS24625	COG2197	response regulator
CO703_RS24635	COG1858	cytochrome C peroxidase
CO703_RS24640	COG0076	glutamate decarboxylase activity
CO703_RS24650	COG2207	Transcriptional regulator
CO703_RS24660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO703_RS24665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS24685	COG2771	luxR family
CO703_RS24690	COG3247	response to pH
CO703_RS24705	COG1285	pathogenesis
CO703_RS24710	COG2197	response regulator
CO703_RS24720	COG3065	identical protein binding
CO703_RS24740	COG1393	Belongs to the ArsC family
CO703_RS24745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CO703_RS24750	COG0640	Transcriptional regulator
CO703_RS24765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CO703_RS24770	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CO703_RS24775	COG0339	signal peptide processing
CO703_RS24785	COG3104	oligopeptide transport
CO703_RS24795	COG0589	response to stress
CO703_RS24805	COG0306	phosphate transporter
CO703_RS24810	COG2081	HI0933 family
CO703_RS24840	COG4372	Transposase
CO703_RS24845	COG3436	PFAM IS66 Orf2 family protein
CO703_RS24895	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS24925	COG0739	heme binding
CO703_RS24935	COG2132	Multicopper oxidase
CO703_RS24940	COG3667	copper resistance
CO703_RS24945	COG2372	response to copper ion
CO703_RS24950	COG1276	copper resistance
CO703_RS24955	COG0745	RESPONSE REGULATOR receiver
CO703_RS24960	COG2205	protein histidine kinase activity
CO703_RS24990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS24995	COG0842	Transport permease protein
CO703_RS24995	COG1129	ABC transporter
CO703_RS25000	COG0842	Transport permease protein
CO703_RS25025	COG0444	Belongs to the ABC transporter superfamily
CO703_RS25030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CO703_RS25035	COG0601	transmembrane transport
CO703_RS25040	COG0747	negative chemotaxis
CO703_RS25045	COG2091	lysine biosynthetic process via aminoadipic acid
CO703_RS25050	COG0628	permease
CO703_RS25065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CO703_RS25080	COG3714	YhhN family
CO703_RS25090	COG3776	membrane
CO703_RS25095	COG0742	ribosomal rna small subunit methyltransferase
CO703_RS25100	COG0552	protein localization to endoplasmic reticulum
CO703_RS25105	COG2884	Cell division ATP-binding protein ftsE
CO703_RS25110	COG2177	Part of the ABC transporter FtsEX involved in
CO703_RS25115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CO703_RS25120	COG0683	leucine binding
CO703_RS25125	COG0456	acetyltransferase
CO703_RS25135	COG0683	leucine binding
CO703_RS25140	COG0559	Belongs to the binding-protein-dependent transport system permease family
CO703_RS25145	COG4177	L-phenylalanine transmembrane transporter activity
CO703_RS25150	COG0411	ABC transporter
CO703_RS25155	COG0410	ABC transporter
CO703_RS25160	COG1653	transport
CO703_RS25165	COG1175	transmembrane transport
CO703_RS25170	COG0395	ABC-type sugar transport system, permease component
CO703_RS25175	COG3842	ATPase activity
CO703_RS25180	COG0584	glycerophosphoryl diester phosphodiesterase
CO703_RS25190	COG0405	Gamma-glutamyltransferase
CO703_RS25210	COG3157	Type VI secretion system effector, Hcp
CO703_RS25215	COG1247	-acetyltransferase
CO703_RS25225	COG0673	inositol 2-dehydrogenase activity
CO703_RS25230	COG1741	Belongs to the pirin family
CO703_RS25235	COG1609	Transcriptional regulator
CO703_RS25240	COG3265	gluconokinase activity
CO703_RS25245	COG2610	gluconate transmembrane transporter activity
CO703_RS25250	COG2095	MarC family integral membrane protein
CO703_RS25255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CO703_RS25280	COG0058	SHG alpha-glucan phosphorylase activity
CO703_RS25290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CO703_RS25310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CO703_RS25325	COG1349	DNA-binding transcription factor activity
CO703_RS25330	COG4650	regulator
CO703_RS25335	COG1690	Belongs to the RtcB family
CO703_RS25350	COG0058	SHG alpha-glucan phosphorylase activity
CO703_RS25355	COG1640	4-alpha-glucanotransferase
CO703_RS25360	COG2610	gluconate transmembrane transporter activity
CO703_RS25380	COG5464	transposase or invertase
CO703_RS25395	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CO703_RS25400	COG1918	ferrous iron import across plasma membrane
CO703_RS25410	COG2183	response to ionizing radiation
CO703_RS25415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CO703_RS25455	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CO703_RS25465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CO703_RS25470	COG1011	Hydrolase
CO703_RS25480	COG0494	nUDIX hydrolase
CO703_RS25485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CO703_RS25490	COG4972	Pilus assembly protein
CO703_RS25495	COG3166	PFAM Fimbrial assembly family protein
CO703_RS25510	COG4796	Type ii and iii secretion system protein
CO703_RS25525	COG3266	domain, Protein
CO703_RS25530	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CO703_RS25535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CO703_RS25545	COG0180	Tryptophanyl-tRNA synthetase
CO703_RS25550	COG2188	Transcriptional regulator
CO703_RS25560	COG3457	Alanine racemase
CO703_RS25565	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CO703_RS25570	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CO703_RS25585	COG0626	cystathionine gamma-synthase activity
CO703_RS25590	COG2188	Transcriptional regulator
CO703_RS25595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CO703_RS25600	COG1082	Xylose isomerase domain protein TIM barrel
CO703_RS25610	COG2222	sugar isomerase
CO703_RS25615	COG0531	amino acid
CO703_RS25630	COG2116	formate transmembrane transporter activity
CO703_RS25635	COG2146	nitrite reductase [NAD(P)H] activity
CO703_RS25640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CO703_RS25650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CO703_RS25660	COG2184	nucleotidyltransferase activity
CO703_RS25665	COG0512	Glutamine amidotransferase of anthranilate synthase
CO703_RS25670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CO703_RS25675	COG1289	transmembrane transporter activity
CO703_RS25680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CO703_RS25690	COG1765	OsmC-like protein
CO703_RS25695	COG3954	Phosphoribulokinase
CO703_RS25705	COG0429	hydrolase of the alpha beta-hydrolase fold
CO703_RS25710	COG0488	(ABC) transporter
CO703_RS25730	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CO703_RS25735	COG1047	Peptidyl-prolyl cis-trans
CO703_RS25745	COG0545	Peptidyl-prolyl cis-trans isomerase
CO703_RS25750	COG2964	Protein conserved in bacteria
CO703_RS25830	COG0089	rRNA binding
CO703_RS25920	COG0201	protein transport
CO703_RS25960	COG0789	Transcriptional regulator
CO703_RS25965	COG3036	rescue of stalled ribosome
CO703_RS25975	COG0569	domain protein
CO703_RS25995	COG0758	DNA mediated transformation
CO703_RS26005	COG0551	DNA topoisomerase type I activity
CO703_RS26025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CO703_RS26065	COG1126	abc transporter atp-binding protein
CO703_RS26070	COG0765	amino acid transport
CO703_RS26075	COG4597	amino acid ABC transporter
CO703_RS26080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CO703_RS26095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CO703_RS26100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CO703_RS26110	COG1309	transcriptional regulator
CO703_RS26120	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CO703_RS26130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CO703_RS26140	COG4145	pantothenate transmembrane transporter activity
CO703_RS26145	COG3924	membrane
CO703_RS26150	COG0439	Biotin carboxylase
CO703_RS26155	COG0511	ligase activity, forming carbon-carbon bonds
CO703_RS26165	COG0604	alcohol dehydrogenase
CO703_RS26170	COG2199	diguanylate cyclase activity
CO703_RS26170	COG2200	EAL domain
CO703_RS26185	COG1077	Cell shape determining protein MreB Mrl
CO703_RS26190	COG1792	Involved in formation and maintenance of cell shape
CO703_RS26195	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CO703_RS26205	COG1530	ribonuclease E activity
CO703_RS26210	COG3164	Protein of unknown function
CO703_RS26215	COG0312	modulator of DNA gyrase
CO703_RS26220	COG0583	DNA-binding transcription factor activity
CO703_RS26240	COG2732	(Barnase) inhibitor
CO703_RS26260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CO703_RS26265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CO703_RS26270	COG3105	Protein conserved in bacteria
CO703_RS26275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CO703_RS26305	COG0625	glutathione transferase activity
CO703_RS26310	COG2969	positive regulation of protein catabolic process
CO703_RS26315	COG3069	C4-dicarboxylate transmembrane transporter activity
CO703_RS26350	COG2731	YhcH YjgK YiaL family protein
CO703_RS26360	COG4804	nuclease activity
CO703_RS26365	COG0493	'glutamate synthase
CO703_RS26370	COG0067	glutamate synthase
CO703_RS26370	COG0069	glutamate synthase activity
CO703_RS26370	COG0070	glutamate synthase
CO703_RS26385	COG1242	4 iron, 4 sulfur cluster binding
CO703_RS26390	COG2198	Histidine kinase
CO703_RS26390	COG0784	Response regulator, receiver
CO703_RS26390	COG5002	protein histidine kinase activity
CO703_RS26395	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CO703_RS26405	COG0515	serine threonine protein kinase
CO703_RS26410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS26425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CO703_RS26430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CO703_RS26435	COG1137	ATPase activity
CO703_RS26440	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CO703_RS26445	COG3117	lipopolysaccharide transmembrane transporter activity
CO703_RS26450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CO703_RS26455	COG0517	IMP dehydrogenase activity
CO703_RS26455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CO703_RS26460	COG0530	calcium, potassium:sodium antiporter activity
CO703_RS26465	COG1127	ABC transporter
CO703_RS26470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CO703_RS26475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CO703_RS26480	COG2854	intermembrane phospholipid transfer
CO703_RS26485	COG3113	response to antibiotic
CO703_RS26490	COG5007	Belongs to the BolA IbaG family
CO703_RS26500	COG3423	Transcriptional regulator
CO703_RS26505	COG0142	geranyltranstransferase activity
CO703_RS26520	COG0697	spore germination
CO703_RS26530	COG2027	D-alanyl-D-alanine carboxypeptidase
CO703_RS26535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CO703_RS26540	COG1534	Rna-binding protein
CO703_RS26550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CO703_RS26555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CO703_RS26565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CO703_RS26575	COG2194	sulfuric ester hydrolase activity
CO703_RS26595	COG0195	Participates in both transcription termination and antitermination
CO703_RS26635	COG0513	Belongs to the DEAD box helicase family
CO703_RS26640	COG0814	amino acid
CO703_RS26645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CO703_RS26650	COG0826	peptidase U32
CO703_RS26655	COG0826	peptidase U32
CO703_RS26660	COG3154	lipid carrier protein
CO703_RS26665	COG3153	acetyltransferase
CO703_RS26680	COG0693	protein deglycase activity
CO703_RS26685	COG0702	epimerase
CO703_RS26690	COG0701	Predicted permease
CO703_RS26695	COG2823	Periplasmic or secreted lipoprotein
CO703_RS26715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CO703_RS26720	COG3539	Fimbrial protein
CO703_RS26725	COG3188	usher protein
CO703_RS26730	COG3121	Chaperone
CO703_RS26735	COG3539	Fimbrial protein
CO703_RS26740	COG0363	glucosamine-6-phosphate deaminase activity
CO703_RS26745	COG3716	PTS system mannose fructose sorbose family IID component
CO703_RS26750	COG3715	PTS system
CO703_RS26755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS26765	COG2222	sugar isomerase
CO703_RS26770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CO703_RS26775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS26780	COG3716	PTS system mannose fructose sorbose family IID component
CO703_RS26790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CO703_RS26805	COG1349	DNA-binding transcription factor activity
CO703_RS26815	COG2002	toxin-antitoxin pair type II binding
CO703_RS26820	COG2721	sulfolactate sulfo-lyase activity
CO703_RS26825	COG2271	Major facilitator Superfamily
CO703_RS26835	COG2084	Dehydrogenase
CO703_RS26840	COG1929	Belongs to the glycerate kinase type-1 family
CO703_RS26850	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS26875	COG0583	DNA-binding transcription factor activity
CO703_RS26880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CO703_RS26890	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CO703_RS26895	COG1882	Formate acetyltransferase
CO703_RS26900	COG0251	oxidation-reduction process
CO703_RS26905	COG1760	l-serine dehydratase
CO703_RS26910	COG0814	amino acid
CO703_RS26925	COG1741	Belongs to the pirin family
CO703_RS26930	COG0583	DNA-binding transcription factor activity
CO703_RS26940	COG3152	Membrane
CO703_RS26945	COG0435	Glutathione S-transferase
CO703_RS26950	COG2259	Doxx family
CO703_RS26960	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CO703_RS26965	COG4575	ribosome binding
CO703_RS26970	COG1422	Protein of unknown function (DUF1090)
CO703_RS26980	COG0586	Pfam SNARE associated Golgi protein
CO703_RS26985	COG2186	Transcriptional regulator
CO703_RS27010	COG2271	Major facilitator Superfamily
CO703_RS27020	COG2721	sulfolactate sulfo-lyase activity
CO703_RS27030	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CO703_RS27035	COG0861	Integral membrane protein TerC family
CO703_RS27040	COG0673	inositol 2-dehydrogenase activity
CO703_RS27045	COG2949	membrane
CO703_RS27050	COG1451	nucleotide metabolic process
CO703_RS27060	COG4680	protein conserved in bacteria
CO703_RS27065	COG5499	transcription regulator containing HTH domain
CO703_RS27070	COG0446	pyridine nucleotide-disulphide oxidoreductase
CO703_RS27070	COG1902	pentaerythritol trinitrate reductase activity
CO703_RS27075	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CO703_RS27075	COG3408	Glycogen debranching enzyme
CO703_RS27085	COG0531	amino acid
CO703_RS27090	COG2731	YhcH YjgK YiaL family protein
CO703_RS27095	COG3250	beta-galactosidase activity
CO703_RS27100	COG1609	Transcriptional regulator
CO703_RS27110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CO703_RS27125	COG0840	transmembrane signaling receptor activity
CO703_RS27130	COG1695	Transcriptional regulator
CO703_RS27135	COG2375	cellular response to nickel ion
CO703_RS27150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CO703_RS27160	COG0358	DNA primase activity
CO703_RS27165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CO703_RS27180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CO703_RS27185	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CO703_RS27195	COG0583	DNA-binding transcription factor activity
CO703_RS27205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CO703_RS27220	COG4991	sh3 domain protein
CO703_RS27230	COG3025	triphosphatase activity
CO703_RS27250	COG2268	Band 7 protein
CO703_RS27255	COG1585	Membrane protein implicated in regulation of membrane protease activity
CO703_RS27265	COG3539	Fimbrial protein
CO703_RS27270	COG3121	Chaperone
CO703_RS27275	COG3188	usher protein
CO703_RS27280	COG3539	Fimbrial protein
CO703_RS27285	COG2960	long-chain fatty acid transporting porin activity
CO703_RS27305	COG3384	dioxygenase
CO703_RS27310	COG0754	glutathionylspermidine amidase activity
CO703_RS27325	COG1538	Outer membrane efflux protein
CO703_RS27330	COG0494	nUDIX hydrolase
CO703_RS27335	COG3151	Protein conserved in bacteria
CO703_RS27340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CO703_RS27345	COG3150	esterase
CO703_RS27350	COG0187	DNA topoisomerase II activity
CO703_RS27355	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CO703_RS27360	COG2249	NAD(P)H dehydrogenase (quinone) activity
CO703_RS27370	COG0642	Histidine kinase
CO703_RS27375	COG0745	RESPONSE REGULATOR receiver
CO703_RS27380	COG3111	PFAM Bacterial OB fold (BOF) protein
CO703_RS27385	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CO703_RS27395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CO703_RS27400	COG0204	Acyl-transferase
CO703_RS27405	COG2132	Multicopper oxidase
CO703_RS27410	COG1032	radical SAM domain protein
CO703_RS27415	COG4238	major outer membrane lipoprotein
CO703_RS27425	COG0656	L-ascorbic acid biosynthetic process
CO703_RS27430	COG1979	alcohol dehydrogenase
CO703_RS27435	COG2207	Transcriptional regulator
CO703_RS27440	COG0586	Pfam SNARE associated Golgi protein
CO703_RS27445	COG0626	cystathionine gamma-synthase activity
CO703_RS27455	COG0811	peptide transport
CO703_RS27460	COG0848	biopolymer transport protein
CO703_RS27465	COG1028	Short-chain dehydrogenase reductase Sdr
CO703_RS27475	COG0667	Aldo Keto reductase
CO703_RS27495	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CO703_RS27500	COG0437	4 iron, 4 sulfur cluster binding
CO703_RS27505	COG5557	Pfam Polysulphide reductase, NrfD
CO703_RS27510	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CO703_RS27515	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CO703_RS27520	COG1773	rubredoxin
CO703_RS27530	COG0298	carbon dioxide binding
CO703_RS27535	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS27545	COG0625	glutathione transferase activity
CO703_RS27550	COG0754	glutathionylspermidine amidase activity
CO703_RS27560	COG0306	phosphate transporter
CO703_RS27565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CO703_RS27570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CO703_RS27575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CO703_RS27580	COG2244	polysaccharide biosynthetic process
CO703_RS27590	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CO703_RS27595	COG0795	lipopolysaccharide-transporting ATPase activity
CO703_RS27605	COG0156	8-amino-7-oxononanoate synthase activity
CO703_RS27610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CO703_RS27620	COG0318	PFAM AMP-dependent synthetase and ligase
CO703_RS27630	COG0456	acetyltransferase
CO703_RS27635	COG2186	Transcriptional regulator
CO703_RS27640	COG0277	FAD linked oxidase domain protein
CO703_RS27645	COG0277	FAD linked oxidase domain protein
CO703_RS27650	COG0247	lactate metabolic process
CO703_RS27655	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CO703_RS27660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CO703_RS27665	COG1620	l-lactate permease
CO703_RS27700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CO703_RS27705	COG1459	type II secretion system
CO703_RS27710	COG2165	general secretion pathway protein
CO703_RS27740	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CO703_RS27770	COG2003	Belongs to the UPF0758 family
CO703_RS27805	COG2020	methyltransferase activity
CO703_RS27810	COG3468	outer membrane autotransporter barrel domain protein
CO703_RS28090	COG4372	Transposase
CO703_RS28095	COG3547	Transposase (IS116 IS110 IS902 family)
CO703_RS28100	COG2801	Transposase and inactivated derivatives
CO703_RS28115	COG3039	Transposase
CO703_RS28120	COG4372	Transposase
CO703_RS28125	COG3436	PFAM IS66 Orf2 family protein
CO703_RS28155	COG3344	reverse transcriptase
CO703_RS28170	COG2826	transposase and inactivated derivatives, IS30 family
CO703_RS28190	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CO703_RS28195	COG1404	Belongs to the peptidase S8 family
CO703_RS28200	COG0464	growth
CO703_RS28205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CO703_RS28245	COG0582	viral genome integration into host DNA
CO703_RS28255	COG1811	Na channel or pump
CO703_RS28265	COG1982	Orn Lys Arg decarboxylase major
CO703_RS28270	COG2211	Major facilitator Superfamily
CO703_RS28285	COG1194	a g-specific adenine glycosylase
CO703_RS28300	COG3171	Protein conserved in bacteria
CO703_RS28310	COG0252	asparaginase activity
CO703_RS28320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CO703_RS28335	COG0762	integral membrane protein
CO703_RS28340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CO703_RS28345	COG2805	Type II/IV secretion system protein
CO703_RS28360	COG0189	ligase activity
CO703_RS28365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CO703_RS28370	COG2356	endonuclease I
CO703_RS28380	COG2814	Major facilitator Superfamily
CO703_RS28405	COG1166	arginine decarboxylase activity
CO703_RS28420	COG0501	Belongs to the peptidase M48B family
CO703_RS28425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CO703_RS28430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CO703_RS28435	COG2213	PTS system mannitol-specific
CO703_RS28440	COG1063	alcohol dehydrogenase
CO703_RS28445	COG1494	fructose-1,6-bisphosphatase
CO703_RS28455	COG1072	(Pantothenic acid kinase))
CO703_RS28460	COG1122	ATPase activity
CO703_RS28465	COG1122	ATPase activity
CO703_RS28500	COG0191	fructose-bisphosphate aldolase activity
CO703_RS28505	COG0668	transmembrane transport
CO703_RS28510	COG1279	arginine transmembrane transporter activity
CO703_RS28515	COG2968	Membrane