locus-tag	class	description
GHT02_RS00050	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS00050	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS00135	COG3111	PFAM Bacterial OB fold (BOF) protein
GHT02_RS00180	COG3561	AntA/AntB antirepressor
GHT02_RS00190	COG0243	molybdopterin cofactor binding
GHT02_RS00195	COG0243	molybdopterin cofactor binding
GHT02_RS00210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GHT02_RS00225	COG4948	Mandelate Racemase Muconate Lactonizing
GHT02_RS00240	COG0582	viral genome integration into host DNA
GHT02_RS00250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHT02_RS00275	COG1396	sequence-specific DNA binding
GHT02_RS00290	COG1846	Transcriptional regulator
GHT02_RS00330	COG1403	HNH endonuclease
GHT02_RS00335	COG0484	heat shock protein binding
GHT02_RS00345	COG1278	Cold shock
GHT02_RS00360	COG3772	lysozyme
GHT02_RS00370	COG1278	Cold shock
GHT02_RS00395	COG5562	phage envelope protein
GHT02_RS00435	COG2826	transposase and inactivated derivatives, IS30 family
GHT02_RS00450	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GHT02_RS00455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GHT02_RS00475	COG0246	Mannitol dehydrogenase
GHT02_RS00485	COG1802	Transcriptional regulator
GHT02_RS00490	COG4221	oxidoreductase activity
GHT02_RS00495	COG0339	signal peptide processing
GHT02_RS00500	COG1546	Belongs to the CinA family
GHT02_RS00505	COG3111	PFAM Bacterial OB fold (BOF) protein
GHT02_RS00510	COG3706	GGDEF domain
GHT02_RS00520	COG2814	Major facilitator Superfamily
GHT02_RS00525	COG0697	spore germination
GHT02_RS00530	COG2188	Transcriptional regulator
GHT02_RS00540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GHT02_RS00545	COG1447	Phosphotransferase system cellobiose-specific component IIA
GHT02_RS00555	COG2723	6-phospho-beta-galactosidase activity
GHT02_RS00565	COG4977	sequence-specific DNA binding
GHT02_RS00570	COG1846	Transcriptional regulator
GHT02_RS00590	COG0583	DNA-binding transcription factor activity
GHT02_RS00595	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS00600	COG2066	Belongs to the glutaminase family
GHT02_RS00610	COG2199	diguanylate cyclase activity
GHT02_RS00620	COG3781	membrane
GHT02_RS00680	COG1396	sequence-specific DNA binding
GHT02_RS00685	COG3550	peptidyl-serine autophosphorylation
GHT02_RS00705	COG3188	usher protein
GHT02_RS00710	COG3539	Fimbrial protein
GHT02_RS00715	COG3539	Fimbrial protein
GHT02_RS00720	COG3539	Fimbrial protein
GHT02_RS00725	COG0243	molybdopterin cofactor binding
GHT02_RS00735	COG2207	Transcriptional regulator
GHT02_RS00745	COG3119	arylsulfatase activity
GHT02_RS00750	COG0641	radical SAM
GHT02_RS00760	COG4178	(ABC) transporter
GHT02_RS00765	COG4771	TonB-dependent receptor
GHT02_RS00770	COG0612	Peptidase, M16
GHT02_RS00775	COG0076	glutamate decarboxylase activity
GHT02_RS00780	COG0531	amino acid
GHT02_RS00785	COG1649	PFAM Uncharacterised BCR, COG1649
GHT02_RS00795	COG2199	diguanylate cyclase activity
GHT02_RS00795	COG2200	EAL domain
GHT02_RS00795	COG2202	Pas domain
GHT02_RS00800	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GHT02_RS00810	COG0601	transmembrane transport
GHT02_RS00815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GHT02_RS00820	COG0444	Belongs to the ABC transporter superfamily
GHT02_RS00825	COG4608	Belongs to the ABC transporter superfamily
GHT02_RS00830	COG1764	response to oxidative stress
GHT02_RS00850	COG1064	alcohol dehydrogenase
GHT02_RS00855	COG3093	addiction module antidote protein HigA
GHT02_RS00860	COG2864	formate dehydrogenase
GHT02_RS00865	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS00875	COG0697	spore germination
GHT02_RS00880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GHT02_RS00885	COG4886	Leucine-rich repeat (LRR) protein
GHT02_RS00890	COG2223	nitrite transmembrane transporter activity
GHT02_RS00895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GHT02_RS00900	COG1140	nitrate reductase beta subunit
GHT02_RS00905	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GHT02_RS00910	COG2181	nitrate reductase activity
GHT02_RS00915	COG0384	phenazine biosynthesis protein PhzF
GHT02_RS00920	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GHT02_RS00925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GHT02_RS00970	COG0625	glutathione transferase activity
GHT02_RS00975	COG1113	amino acid transport
GHT02_RS00980	COG3391	amine dehydrogenase activity
GHT02_RS00985	COG4772	TonB-dependent receptor
GHT02_RS00990	COG1802	Transcriptional regulator
GHT02_RS00995	COG2130	NADP-dependent
GHT02_RS01000	COG1247	-acetyltransferase
GHT02_RS01005	COG3238	Protein conserved in bacteria
GHT02_RS01035	COG1177	transmembrane transport
GHT02_RS01040	COG1176	ABC-type spermidine putrescine transport system, permease component I
GHT02_RS01045	COG3842	ATPase activity
GHT02_RS01050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GHT02_RS01055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GHT02_RS01060	COG1598	PFAM Uncharacterised protein family UPF0150
GHT02_RS01065	COG1724	mRNA binding
GHT02_RS01075	COG0826	peptidase U32
GHT02_RS01080	COG1396	sequence-specific DNA binding
GHT02_RS01085	COG3135	benzoate transporter
GHT02_RS01090	COG0675	Transposase, IS605 OrfB family
GHT02_RS01105	COG0500	methyltransferase
GHT02_RS01110	COG1275	C4-dicarboxylate transporter malic acid transport protein
GHT02_RS01115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GHT02_RS01120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GHT02_RS01125	COG2841	Protein conserved in bacteria
GHT02_RS01135	COG5383	Protein conserved in bacteria
GHT02_RS01140	COG0583	DNA-binding transcription factor activity
GHT02_RS01145	COG0840	transmembrane signaling receptor activity
GHT02_RS01160	COG3038	cytochrome b561
GHT02_RS01165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GHT02_RS01170	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS01175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GHT02_RS01180	COG1643	Atp-dependent helicase
GHT02_RS01190	COG2453	phosphatase
GHT02_RS01190	COG0671	phosphoesterase, PA-phosphatase related
GHT02_RS01195	COG2267	carboxylic ester hydrolase activity
GHT02_RS01200	COG4589	Belongs to the CDS family
GHT02_RS01205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHT02_RS01215	COG0667	Aldo Keto reductase
GHT02_RS01220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GHT02_RS01225	COG3327	negative regulation of DNA-templated transcription, initiation
GHT02_RS01230	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GHT02_RS01235	COG0183	Belongs to the thiolase family
GHT02_RS01240	COG2050	protein possibly involved in aromatic compounds catabolism
GHT02_RS01245	COG1250	3-hydroxyacyl-CoA dehydrogenase
GHT02_RS01250	COG1024	Enoyl-CoA hydratase
GHT02_RS01255	COG1024	Enoyl-CoA hydratase
GHT02_RS01260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GHT02_RS01265	COG2151	metal-sulfur cluster biosynthetic enzyme
GHT02_RS01270	COG3396	Phenylacetate-CoA oxygenase
GHT02_RS01275	COG3460	Phenylacetate-CoA oxygenase
GHT02_RS01280	COG3396	Phenylacetate-CoA oxygenase
GHT02_RS01285	COG2030	dehydratase
GHT02_RS01285	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS01290	COG3733	amine oxidase
GHT02_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS01300	COG2207	Transcriptional regulator
GHT02_RS01305	COG3784	Protein of unknown function (DUF1318)
GHT02_RS01325	COG2911	Protein conserved in bacteria
GHT02_RS01330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHT02_RS01335	COG3187	Heat shock protein
GHT02_RS01340	COG3042	response to heat
GHT02_RS01345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GHT02_RS01345	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GHT02_RS01345	COG1013	pyruvate-flavodoxin oxidoreductase activity
GHT02_RS01345	COG0674	pyruvate-flavodoxin oxidoreductase activity
GHT02_RS01350	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GHT02_RS01355	COG0589	response to stress
GHT02_RS01365	COG0513	Belongs to the DEAD box helicase family
GHT02_RS01375	COG3706	GGDEF domain
GHT02_RS01380	COG2840	Smr protein MutS2
GHT02_RS01385	COG0583	DNA-binding transcription factor activity
GHT02_RS01390	COG1473	amidohydrolase
GHT02_RS01395	COG1473	amidohydrolase
GHT02_RS01400	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GHT02_RS01405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GHT02_RS01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GHT02_RS01415	COG0589	response to stress
GHT02_RS01420	COG3182	Iron-regulated membrane protein
GHT02_RS01425	COG0668	transmembrane transport
GHT02_RS01430	COG4166	transmembrane transport
GHT02_RS01435	COG0583	DNA-binding transcription factor activity
GHT02_RS01440	COG1073	alpha beta
GHT02_RS01445	COG1073	alpha beta
GHT02_RS01450	COG0702	epimerase
GHT02_RS01455	COG2866	Carboxypeptidase
GHT02_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
GHT02_RS01465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GHT02_RS01470	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GHT02_RS01480	COG3106	COG3106 Predicted ATPase
GHT02_RS01485	COG1609	Transcriptional regulator
GHT02_RS01495	COG3842	ATPase activity
GHT02_RS01500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GHT02_RS01505	COG1554	hydrolase, family 65, central catalytic
GHT02_RS01510	COG0673	inositol 2-dehydrogenase activity
GHT02_RS01520	COG1063	alcohol dehydrogenase
GHT02_RS01525	COG0395	ABC-type sugar transport system, permease component
GHT02_RS01530	COG1175	transmembrane transport
GHT02_RS01535	COG1653	transport
GHT02_RS01540	COG0366	Alpha amylase catalytic
GHT02_RS01545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHT02_RS01555	COG1983	PspC domain protein
GHT02_RS01565	COG1842	Phage shock protein A
GHT02_RS01570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GHT02_RS01575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GHT02_RS01580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GHT02_RS01585	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS01590	COG1396	sequence-specific DNA binding
GHT02_RS01590	COG1917	Cupin 2, conserved barrel domain protein
GHT02_RS01595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GHT02_RS01610	COG0531	amino acid
GHT02_RS01620	COG4166	transmembrane transport
GHT02_RS01625	COG4168	peptide transport system, permease
GHT02_RS01630	COG4171	peptide transport system, permease
GHT02_RS01635	COG4172	Belongs to the ABC transporter superfamily
GHT02_RS01640	COG4172	Belongs to the ABC transporter superfamily
GHT02_RS01645	COG2852	Protein conserved in bacteria
GHT02_RS01650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GHT02_RS01655	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GHT02_RS01655	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GHT02_RS01670	COG5001	Diguanylate cyclase
GHT02_RS01680	COG1349	DNA-binding transcription factor activity
GHT02_RS01690	COG0023	Translation Initiation Factor
GHT02_RS01700	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GHT02_RS01705	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GHT02_RS01710	COG0671	phosphoesterase, PA-phosphatase related
GHT02_RS01720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GHT02_RS01740	COG0583	DNA-binding transcription factor activity
GHT02_RS01745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHT02_RS01755	COG0616	signal peptide processing
GHT02_RS01760	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS01765	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GHT02_RS01770	COG1187	pseudouridine synthase activity
GHT02_RS01775	COG0009	L-threonylcarbamoyladenylate synthase
GHT02_RS01780	COG0613	PHP domain protein
GHT02_RS01790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GHT02_RS01795	COG0512	Glutamine amidotransferase of anthranilate synthase
GHT02_RS01795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GHT02_RS01800	COG0135	phosphoribosylanthranilate isomerase activity
GHT02_RS01800	COG0134	indole-3-glycerol-phosphate synthase activity
GHT02_RS01815	COG3729	General stress protein
GHT02_RS01825	COG3685	Protein conserved in bacteria
GHT02_RS01830	COG3685	Protein conserved in bacteria
GHT02_RS01860	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS01860	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS02005	COG3772	lysozyme
GHT02_RS02080	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GHT02_RS02085	COG1403	HNH endonuclease
GHT02_RS02190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHT02_RS02200	COG0582	viral genome integration into host DNA
GHT02_RS02205	COG3047	cAMP biosynthetic process
GHT02_RS02225	COG1607	acyl-coa hydrolase
GHT02_RS02230	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GHT02_RS02235	COG2350	Protein conserved in bacteria
GHT02_RS02240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GHT02_RS02260	COG4608	Belongs to the ABC transporter superfamily
GHT02_RS02265	COG0444	Belongs to the ABC transporter superfamily
GHT02_RS02270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GHT02_RS02275	COG0601	transmembrane transport
GHT02_RS02280	COG4166	transmembrane transport
GHT02_RS02290	COG2095	MarC family integral membrane protein
GHT02_RS02295	COG1454	alcohol dehydrogenase
GHT02_RS02295	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS02300	COG1435	thymidine kinase activity
GHT02_RS02310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GHT02_RS02315	COG0745	RESPONSE REGULATOR receiver
GHT02_RS02320	COG1752	Esterase of the alpha-beta hydrolase superfamily
GHT02_RS02330	COG0788	formyltetrahydrofolate deformylase activity
GHT02_RS02345	COG2181	nitrate reductase activity
GHT02_RS02350	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GHT02_RS02355	COG1140	nitrate reductase beta subunit
GHT02_RS02360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GHT02_RS02365	COG2223	nitrite transmembrane transporter activity
GHT02_RS02370	COG3850	Histidine kinase
GHT02_RS02375	COG2197	response regulator
GHT02_RS02380	COG4932	domain protein
GHT02_RS02385	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GHT02_RS02390	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GHT02_RS02395	COG4572	Cation transport regulator
GHT02_RS02400	COG0387	Pfam Sodium calcium exchanger
GHT02_RS02430	COG2842	Transposition protein
GHT02_RS02460	COG4396	Host-nuclease inhibitor protein Gam
GHT02_RS02510	COG5566	PFAM Mor transcription activator
GHT02_RS02550	COG4373	Mu-like prophage FluMu protein gp28
GHT02_RS02555	COG4383	Mu-like prophage protein gp29
GHT02_RS02560	COG2369	cell adhesion
GHT02_RS02570	COG5005	Phage virion morphogenesis
GHT02_RS02575	COG4388	Caudovirus prohead serine protease
GHT02_RS02580	COG4397	Mu-like prophage major head subunit gpT
GHT02_RS02605	COG4386	tail sheath protein
GHT02_RS02615	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
GHT02_RS02635	COG4384	Bacteriophage Mu Gp45 protein
GHT02_RS02645	COG3299	homolog of phage Mu protein gp47
GHT02_RS02665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GHT02_RS02710	COG2912	Transglutaminase-like superfamily
GHT02_RS02715	COG3094	Invasion gene expression up-regulator, SirB
GHT02_RS02720	COG2890	protein-(glutamine-N5) methyltransferase activity
GHT02_RS02745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHT02_RS02750	COG0659	secondary active sulfate transmembrane transporter activity
GHT02_RS02765	COG0012	GTP binding
GHT02_RS02770	COG3468	outer membrane autotransporter barrel domain protein
GHT02_RS02775	COG3284	Transcriptional regulator
GHT02_RS02780	COG2376	Dihydroxyacetone kinase
GHT02_RS02785	COG1461	Dihydroxyacetone kinase
GHT02_RS02790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHT02_RS02790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS02790	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GHT02_RS02810	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GHT02_RS02820	COG1619	proteins homologs of microcin C7 resistance protein MccF
GHT02_RS02830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GHT02_RS02840	COG2719	SpoVR family
GHT02_RS02855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GHT02_RS02860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHT02_RS02865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GHT02_RS02880	COG0179	Fumarylacetoacetate (FAA) hydrolase
GHT02_RS02905	COG2894	cell division
GHT02_RS02960	COG2200	EAL domain
GHT02_RS02985	COG2200	EAL domain
GHT02_RS02990	COG0789	Transcriptional regulator
GHT02_RS02995	COG5562	phage envelope protein
GHT02_RS03015	COG0538	isocitrate dehydrogenase activity
GHT02_RS03020	COG1187	pseudouridine synthase activity
GHT02_RS03040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GHT02_RS03050	COG2205	protein histidine kinase activity
GHT02_RS03055	COG2850	peptidyl-arginine hydroxylation
GHT02_RS03065	COG3842	ATPase activity
GHT02_RS03075	COG1177	transmembrane transport
GHT02_RS03080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GHT02_RS03090	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GHT02_RS03095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GHT02_RS03105	COG4591	ABC-type transport system involved in lipoprotein release permease component
GHT02_RS03110	COG1136	(ABC) transporter
GHT02_RS03115	COG4591	ABC-type transport system involved in lipoprotein release permease component
GHT02_RS03120	COG4763	Acyl-transferase
GHT02_RS03125	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GHT02_RS03140	COG1309	transcriptional regulator
GHT02_RS03145	COG3134	Outer membrane lipoprotein
GHT02_RS03150	COG1252	NADH dehydrogenase
GHT02_RS03170	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GHT02_RS03175	COG5633	Lipoprotein
GHT02_RS03180	COG0537	adenosine 5'-monophosphoramidase activity
GHT02_RS03185	COG4773	Receptor
GHT02_RS03190	COG1263	PTS System
GHT02_RS03190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS03195	COG0084	hydrolase, TatD family'
GHT02_RS03200	COG0470	DNA polymerase III
GHT02_RS03210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GHT02_RS03215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GHT02_RS03220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GHT02_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS03235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GHT02_RS03255	COG1399	metal-binding, possibly nucleic acid-binding protein
GHT02_RS03260	COG0424	maF-like protein
GHT02_RS03265	COG0564	pseudouridine synthase activity
GHT02_RS03270	COG1530	ribonuclease E activity
GHT02_RS03280	COG1256	bacterial-type flagellum assembly
GHT02_RS03285	COG1705	Flagellar rod assembly protein muramidase FlgJ
GHT02_RS03285	COG3951	Flagellar rod assembly protein muramidase FlgJ
GHT02_RS03300	COG4786	Flagellar basal body rod
GHT02_RS03305	COG4787	bacterial-type flagellum-dependent cell motility
GHT02_RS03310	COG1749	Flagellar hook protein flgE
GHT02_RS03315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GHT02_RS03320	COG1558	bacterial-type flagellum-dependent cell motility
GHT02_RS03325	COG1815	bacterial-type flagellum-dependent cell motility
GHT02_RS03330	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GHT02_RS03335	COG2747	anti-sigma28 factor FlgM
GHT02_RS03340	COG3418	PFAM FlgN family protein
GHT02_RS03345	COG0728	peptidoglycan biosynthetic process
GHT02_RS03350	COG0673	inositol 2-dehydrogenase activity
GHT02_RS03360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GHT02_RS03370	COG2999	glutathione oxidoreductase activity
GHT02_RS03405	COG3038	cytochrome b561
GHT02_RS03410	COG2353	YceI-like domain
GHT02_RS03420	COG1560	Kdo2-lipid A biosynthetic process
GHT02_RS03435	COG5645	(Lipo)protein
GHT02_RS03440	COG2943	transferase activity, transferring hexosyl groups
GHT02_RS03455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHT02_RS03460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GHT02_RS03485	COG2197	response regulator
GHT02_RS03500	COG1462	curli production assembly transport component CsgG
GHT02_RS03510	COG3381	protein complex oligomerization
GHT02_RS03550	COG0457	Tetratricopeptide repeat
GHT02_RS03555	COG1649	PFAM Uncharacterised BCR, COG1649
GHT02_RS03555	COG0726	polysaccharide deacetylase
GHT02_RS03560	COG1215	transferase activity, transferring glycosyl groups
GHT02_RS03565	COG3658	cytochrome
GHT02_RS03570	COG1702	phosphate starvation-inducible protein PhoH
GHT02_RS03590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GHT02_RS03600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GHT02_RS03600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GHT02_RS03600	COG0506	proline dehydrogenase activity
GHT02_RS03605	COG1309	transcriptional regulator
GHT02_RS03640	COG2233	PERMEase
GHT02_RS03645	COG3729	General stress protein
GHT02_RS03685	COG0243	molybdopterin cofactor binding
GHT02_RS03690	COG3005	denitrification pathway
GHT02_RS03695	COG0745	RESPONSE REGULATOR receiver
GHT02_RS03700	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS03705	COG0784	Response regulator, receiver
GHT02_RS03705	COG2198	Histidine kinase
GHT02_RS03705	COG2205	protein histidine kinase activity
GHT02_RS03710	COG0348	domain, Protein
GHT02_RS03730	COG1278	Cold shock
GHT02_RS03735	COG1278	Cold shock
GHT02_RS03755	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GHT02_RS03760	COG1596	polysaccharide export
GHT02_RS03765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHT02_RS03770	COG3206	protein involved in exopolysaccharide biosynthesis
GHT02_RS03770	COG0489	protein tyrosine kinase activity
GHT02_RS03785	COG1294	oxidase, subunit
GHT02_RS03790	COG1271	oxidase subunit
GHT02_RS03795	COG1773	rubredoxin
GHT02_RS03800	COG1999	signal sequence binding
GHT02_RS03805	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GHT02_RS03810	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
GHT02_RS03815	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GHT02_RS03820	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GHT02_RS03830	COG0670	Belongs to the BI1 family
GHT02_RS03835	COG2920	part of a sulfur-relay system
GHT02_RS03840	COG1254	Belongs to the acylphosphatase family
GHT02_RS03855	COG1832	CoA-binding protein
GHT02_RS03870	COG0210	DNA helicase
GHT02_RS03875	COG3304	Inner membrane component domain
GHT02_RS03880	COG1289	transmembrane transporter activity
GHT02_RS03885	COG3070	regulator of competence-specific genes
GHT02_RS03895	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GHT02_RS03895	COG2885	chlorophyll binding
GHT02_RS03905	COG1067	ATP-dependent peptidase activity
GHT02_RS03915	COG3130	regulation of translation
GHT02_RS03920	COG3009	Protein conserved in bacteria
GHT02_RS03925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GHT02_RS03925	COG3008	intermembrane lipid transfer
GHT02_RS03930	COG2995	paraquat-inducible protein a
GHT02_RS03935	COG0488	(ABC) transporter
GHT02_RS03945	COG3217	Mosc domain protein beta barrel domain protein
GHT02_RS03945	COG0633	Ferredoxin
GHT02_RS03960	COG3121	Chaperone
GHT02_RS03965	COG3539	Fimbrial protein
GHT02_RS03970	COG3539	Fimbrial protein
GHT02_RS03975	COG3539	Fimbrial protein
GHT02_RS03980	COG3188	usher protein
GHT02_RS03985	COG3121	Chaperone
GHT02_RS03990	COG3539	Fimbrial protein
GHT02_RS03995	COG0431	NADPH-dependent FMN reductase
GHT02_RS04000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GHT02_RS04010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GHT02_RS04020	COG0308	aminopeptidase N
GHT02_RS04040	COG1448	Aminotransferase
GHT02_RS04045	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS04050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GHT02_RS04055	COG3108	Peptidase M15
GHT02_RS04060	COG2989	Protein conserved in bacteria
GHT02_RS04070	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GHT02_RS04080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GHT02_RS04085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GHT02_RS04090	COG3173	Aminoglycoside phosphotransferase
GHT02_RS04105	COG3214	Protein conserved in bacteria
GHT02_RS04115	COG1132	(ABC) transporter
GHT02_RS04120	COG2333	competence protein COMEC
GHT02_RS04120	COG0658	competence protein
GHT02_RS04130	COG0539	negative regulation of cytoplasmic translation
GHT02_RS04140	COG0501	Belongs to the peptidase M48B family
GHT02_RS04155	COG2323	membrane
GHT02_RS04160	COG1944	ATP diphosphatase activity
GHT02_RS04165	COG2116	formate transmembrane transporter activity
GHT02_RS04170	COG1882	Formate acetyltransferase
GHT02_RS04175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHT02_RS04180	COG2249	NAD(P)H dehydrogenase (quinone) activity
GHT02_RS04185	COG0583	DNA-binding transcription factor activity
GHT02_RS04190	COG0531	amino acid
GHT02_RS04200	COG1335	isochorismatase
GHT02_RS04205	COG3302	dmso reductase anchor subunit
GHT02_RS04210	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS04215	COG0243	molybdopterin cofactor binding
GHT02_RS04225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GHT02_RS04240	COG1522	sequence-specific DNA binding
GHT02_RS04245	COG0492	ferredoxin-NADP+ reductase activity
GHT02_RS04250	COG4988	ABC transporter
GHT02_RS04255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GHT02_RS04275	COG0542	response to heat
GHT02_RS04285	COG1278	Cold shock
GHT02_RS04295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS04300	COG2990	Protein conserved in bacteria
GHT02_RS04305	COG3593	DNA synthesis involved in DNA repair
GHT02_RS04310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GHT02_RS04315	COG2431	L-lysine efflux transmembrane transporter activity
GHT02_RS04325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GHT02_RS04330	COG0028	Belongs to the TPP enzyme family
GHT02_RS04335	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GHT02_RS04340	COG0702	epimerase
GHT02_RS04345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GHT02_RS04350	COG3023	N-Acetylmuramoyl-L-alanine amidase
GHT02_RS04365	COG1126	abc transporter atp-binding protein
GHT02_RS04370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS04375	COG4215	(ABC) transporter
GHT02_RS04380	COG4160	amino acid transport
GHT02_RS04385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS04400	COG1177	transmembrane transport
GHT02_RS04405	COG1176	ABC-type spermidine putrescine transport system, permease component I
GHT02_RS04410	COG3842	ATPase activity
GHT02_RS04415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GHT02_RS04430	COG0778	Nitroreductase
GHT02_RS04440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GHT02_RS04495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GHT02_RS04510	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GHT02_RS04545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GHT02_RS04585	COG4695	Portal protein
GHT02_RS04685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GHT02_RS04690	COG3226	Transcriptional regulator
GHT02_RS04695	COG0738	Major facilitator superfamily
GHT02_RS04700	COG0561	phosphatase activity
GHT02_RS04710	COG2814	Major facilitator Superfamily
GHT02_RS04715	COG0671	phosphoesterase, PA-phosphatase related
GHT02_RS04720	COG1349	DNA-binding transcription factor activity
GHT02_RS04725	COG1686	Belongs to the peptidase S11 family
GHT02_RS04730	COG0625	glutathione transferase activity
GHT02_RS04735	COG2133	pyrroloquinoline quinone binding
GHT02_RS04750	COG2199	diguanylate cyclase activity
GHT02_RS04755	COG2200	EAL domain
GHT02_RS04780	COG1446	asparaginase
GHT02_RS04785	COG0303	'Molybdopterin
GHT02_RS04790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GHT02_RS04795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GHT02_RS04800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHT02_RS04805	COG1882	Formate acetyltransferase
GHT02_RS04810	COG0561	phosphatase activity
GHT02_RS04820	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS04825	COG0488	(ABC) transporter
GHT02_RS04830	COG1376	ErfK ybiS ycfS ynhG family protein
GHT02_RS04835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GHT02_RS04840	COG1321	iron dependent repressor
GHT02_RS04850	COG2194	sulfuric ester hydrolase activity
GHT02_RS04855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GHT02_RS04865	COG5006	permease, DMT superfamily
GHT02_RS04875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS04880	COG0765	amino acid transport
GHT02_RS04885	COG1126	abc transporter atp-binding protein
GHT02_RS04890	COG0668	transmembrane transport
GHT02_RS04905	COG4774	siderophore transport
GHT02_RS04915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GHT02_RS04925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GHT02_RS04930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GHT02_RS04935	COG1199	ATP-dependent helicase activity
GHT02_RS04945	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS04950	COG0513	Belongs to the DEAD box helicase family
GHT02_RS04955	COG1309	transcriptional regulator
GHT02_RS04965	COG1131	(ABC) transporter
GHT02_RS04970	COG0842	Transport permease protein
GHT02_RS04975	COG0842	Transport permease protein
GHT02_RS04985	COG3568	Endonuclease Exonuclease Phosphatase
GHT02_RS04990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHT02_RS04995	COG0392	lysyltransferase activity
GHT02_RS05000	COG0670	Belongs to the BI1 family
GHT02_RS05005	COG0670	Belongs to the BI1 family
GHT02_RS05010	COG0314	molybdopterin synthase activity
GHT02_RS05015	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GHT02_RS05025	COG0521	Mo-molybdopterin cofactor biosynthetic process
GHT02_RS05035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GHT02_RS05045	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GHT02_RS05050	COG2226	methyltransferase
GHT02_RS05065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GHT02_RS05070	COG1881	PFAM PEBP family protein
GHT02_RS05075	COG4677	pectinesterase activity
GHT02_RS05080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GHT02_RS05085	COG0471	metal ion transport
GHT02_RS05090	COG2828	Protein conserved in bacteria
GHT02_RS05095	COG0583	DNA-binding transcription factor activity
GHT02_RS05105	COG0561	phosphatase activity
GHT02_RS05115	COG4149	molybdate abc transporter
GHT02_RS05120	COG0725	ABC transporter, periplasmic molybdate-binding protein
GHT02_RS05130	COG2005	Transcriptional regulator
GHT02_RS05130	COG3585	molybdate ion transport
GHT02_RS05135	COG1119	ATPase activity
GHT02_RS05140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GHT02_RS05145	COG1085	galactose-1-phosphate uridylyltransferase
GHT02_RS05155	COG2017	converts alpha-aldose to the beta-anomer
GHT02_RS05165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHT02_RS05175	COG1230	cation diffusion facilitator family transporter
GHT02_RS05180	COG3201	nicotinamide mononucleotide transporter
GHT02_RS05225	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GHT02_RS05230	COG2885	chlorophyll binding
GHT02_RS05240	COG3064	Membrane
GHT02_RS05245	COG0848	biopolymer transport protein
GHT02_RS05250	COG0811	peptide transport
GHT02_RS05255	COG0824	Thioesterase
GHT02_RS05260	COG3790	cyd operon protein YbgE
GHT02_RS05265	COG4890	Cyd operon protein YbgT
GHT02_RS05270	COG1294	oxidase, subunit
GHT02_RS05275	COG1271	oxidase subunit
GHT02_RS05280	COG0383	alpha-mannosidase activity
GHT02_RS05285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS05285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS05285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS05290	COG2188	Transcriptional regulator
GHT02_RS05295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GHT02_RS05305	COG0508	dehydrogenase complex catalyzes the overall conversion of
GHT02_RS05310	COG0567	Dehydrogenase, E1 component
GHT02_RS05315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GHT02_RS05320	COG1053	succinate dehydrogenase
GHT02_RS05325	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GHT02_RS05330	COG2009	succinate dehydrogenase
GHT02_RS05340	COG0372	Belongs to the citrate synthase family
GHT02_RS05345	COG3539	Fimbrial protein
GHT02_RS05350	COG3188	usher protein
GHT02_RS05355	COG3121	Chaperone
GHT02_RS05360	COG3539	Fimbrial protein
GHT02_RS05365	COG3180	Ammonia monooxygenase
GHT02_RS05380	COG1984	allophanate hydrolase subunit 2
GHT02_RS05385	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GHT02_RS05390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GHT02_RS05400	COG0415	Belongs to the DNA photolyase family
GHT02_RS05405	COG3272	Protein of unknown function (DUF1722)
GHT02_RS05435	COG3209	COG3209 Rhs family protein
GHT02_RS05465	COG2205	protein histidine kinase activity
GHT02_RS05470	COG0745	RESPONSE REGULATOR receiver
GHT02_RS05480	COG1982	Orn Lys Arg decarboxylase major
GHT02_RS05485	COG0531	amino acid
GHT02_RS05490	COG0033	Phosphoglucomutase
GHT02_RS05495	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GHT02_RS05500	COG0596	Alpha beta hydrolase
GHT02_RS05510	COG0716	FMN binding
GHT02_RS05520	COG0735	belongs to the Fur family
GHT02_RS05540	COG1263	PTS System
GHT02_RS05540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS05540	COG2190	(PTS) system
GHT02_RS05550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GHT02_RS05555	COG1846	Transcriptional regulator
GHT02_RS05555	COG1940	carbohydrate kinase activity
GHT02_RS05560	COG0647	UMP catabolic process
GHT02_RS05565	COG0367	asparagine synthase
GHT02_RS05605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GHT02_RS05615	COG1702	phosphate starvation-inducible protein PhoH
GHT02_RS05625	COG4535	Mg2 and Co2 transporter CorC
GHT02_RS05630	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GHT02_RS05640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS05645	COG0765	amino acid transport
GHT02_RS05650	COG0765	amino acid transport
GHT02_RS05655	COG1126	abc transporter atp-binding protein
GHT02_RS05665	COG0443	Heat shock 70 kDa protein
GHT02_RS05670	COG2214	Heat shock protein DnaJ domain protein
GHT02_RS05680	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GHT02_RS05685	COG2214	Heat shock protein DnaJ domain protein
GHT02_RS05695	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GHT02_RS05700	COG2888	peptidyl-tyrosine sulfation
GHT02_RS05715	COG1466	dna polymerase III delta subunit
GHT02_RS05725	COG0406	alpha-ribazole phosphatase activity
GHT02_RS05730	COG0799	negative regulation of ribosome biogenesis
GHT02_RS05740	COG0768	penicillin binding
GHT02_RS05745	COG0772	Belongs to the SEDS family
GHT02_RS05750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GHT02_RS05755	COG1686	Belongs to the peptidase S11 family
GHT02_RS05770	COG0583	DNA-binding transcription factor activity
GHT02_RS05780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GHT02_RS05785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GHT02_RS05805	COG3069	C4-dicarboxylate transmembrane transporter activity
GHT02_RS05810	COG4565	transcriptional regulatory protein
GHT02_RS05815	COG3290	protein histidine kinase activity
GHT02_RS05820	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GHT02_RS05830	COG2301	Belongs to the HpcH HpaI aldolase family
GHT02_RS05835	COG3051	citrate lyase alpha subunit
GHT02_RS05850	COG0471	metal ion transport
GHT02_RS05855	COG3719	Belongs to the RNase T2 family
GHT02_RS05860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GHT02_RS05865	COG1063	alcohol dehydrogenase
GHT02_RS05870	COG0589	response to stress
GHT02_RS05875	COG3634	alkyl hydroperoxide reductase activity
GHT02_RS05880	COG0450	alkyl hydroperoxide reductase
GHT02_RS05885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GHT02_RS05890	COG0583	DNA-binding transcription factor activity
GHT02_RS05895	COG3969	phosphoadenosine phosphosulfate
GHT02_RS05900	COG1475	DNA binding
GHT02_RS05905	COG0436	Aminotransferase
GHT02_RS05910	COG0371	Dehydrogenase
GHT02_RS05915	COG2879	small protein
GHT02_RS05920	COG1966	Carbon starvation protein
GHT02_RS05925	COG2050	protein possibly involved in aromatic compounds catabolism
GHT02_RS05930	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS05935	COG1535	isochorismatase
GHT02_RS05935	COG3433	isochorismatase activity
GHT02_RS05940	COG1021	2,3-dihydroxybenzoate-AMP ligase
GHT02_RS05945	COG1169	isochorismate synthase
GHT02_RS05950	COG4592	Periplasmic binding protein
GHT02_RS05960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GHT02_RS05965	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GHT02_RS05970	COG1120	ATPase activity
GHT02_RS05975	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GHT02_RS05980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GHT02_RS05980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GHT02_RS05985	COG3251	PFAM MbtH domain protein
GHT02_RS05990	COG2382	esterase
GHT02_RS06000	COG2977	Belongs to the P-Pant transferase superfamily
GHT02_RS06025	COG2315	Protein conserved in bacteria
GHT02_RS06030	COG0778	Nitroreductase
GHT02_RS06035	COG0668	transmembrane transport
GHT02_RS06040	COG1113	amino acid transport
GHT02_RS06045	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GHT02_RS06050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS06055	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS06060	COG1538	Outer membrane efflux protein
GHT02_RS06065	COG0745	RESPONSE REGULATOR receiver
GHT02_RS06070	COG5002	protein histidine kinase activity
GHT02_RS06075	COG3501	Rhs element vgr protein
GHT02_RS06090	COG5433	transposase activity
GHT02_RS06095	COG1215	transferase activity, transferring glycosyl groups
GHT02_RS06100	COG4783	chaperone-mediated protein folding
GHT02_RS06110	COG2207	Transcriptional regulator
GHT02_RS06115	COG4571	Outer membrane protease
GHT02_RS06130	COG0500	methyltransferase
GHT02_RS06135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GHT02_RS06140	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS06175	COG1196	nuclear chromosome segregation
GHT02_RS06225	COG1030	water channel activity
GHT02_RS06245	COG4220	transposase activity
GHT02_RS06265	COG3772	lysozyme
GHT02_RS06330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GHT02_RS06340	COG2076	Multidrug Resistance protein
GHT02_RS06420	COG0582	viral genome integration into host DNA
GHT02_RS06430	COG2197	response regulator
GHT02_RS06435	COG3539	Fimbrial protein
GHT02_RS06440	COG3539	Fimbrial protein
GHT02_RS06450	COG3121	Chaperone
GHT02_RS06455	COG3539	Fimbrial protein
GHT02_RS06465	COG2501	S4 domain
GHT02_RS06470	COG1988	membrane-bound metal-dependent
GHT02_RS06480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHT02_RS06490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GHT02_RS06495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GHT02_RS06500	COG0549	Belongs to the carbamate kinase family
GHT02_RS06510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GHT02_RS06515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GHT02_RS06520	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GHT02_RS06525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GHT02_RS06530	COG3257	ureidoglycine aminohydrolase activity
GHT02_RS06535	COG1929	Belongs to the glycerate kinase type-1 family
GHT02_RS06540	COG2233	PERMEase
GHT02_RS06550	COG1953	Uracil, thiamine, allantoin
GHT02_RS06555	COG2084	Dehydrogenase
GHT02_RS06560	COG3622	Belongs to the hyi family
GHT02_RS06565	COG3960	tartronate-semialdehyde synthase activity
GHT02_RS06570	COG1414	Transcriptional regulator
GHT02_RS06580	COG0583	DNA-binding transcription factor activity
GHT02_RS06605	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GHT02_RS06610	COG4181	ATPase activity
GHT02_RS06615	COG2755	lipolytic protein G-D-S-L family
GHT02_RS06620	COG0300	oxidoreductase activity
GHT02_RS06625	COG3118	belongs to the thioredoxin family
GHT02_RS06630	COG0390	transport system, permease component
GHT02_RS06635	COG4619	ABC transporter
GHT02_RS06640	COG0330	HflC and HflK could
GHT02_RS06645	COG1585	Membrane protein implicated in regulation of membrane protease activity
GHT02_RS06650	COG0789	Transcriptional regulator
GHT02_RS06655	COG0531	amino acid
GHT02_RS06660	COG2066	Belongs to the glutaminase family
GHT02_RS06665	COG2217	Heavy metal translocating P-type atpase
GHT02_RS06670	COG3093	addiction module antidote protein HigA
GHT02_RS06675	COG3735	TraB family
GHT02_RS06680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GHT02_RS06685	COG0737	Belongs to the 5'-nucleotidase family
GHT02_RS06690	COG2223	nitrite transmembrane transporter activity
GHT02_RS06695	COG4651	solute:proton antiporter activity
GHT02_RS06695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GHT02_RS06700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHT02_RS06735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHT02_RS06745	COG2832	Protein of unknown function (DUF454)
GHT02_RS06750	COG3923	Primosomal replication protein n
GHT02_RS06760	COG3264	Mechanosensitive ion channel
GHT02_RS06760	COG1196	nuclear chromosome segregation
GHT02_RS06765	COG1309	transcriptional regulator
GHT02_RS06770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS06775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GHT02_RS06790	COG0110	maltose O-acetyltransferase activity
GHT02_RS06800	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GHT02_RS06805	COG5507	3-demethylubiquinone-9 3-methyltransferase
GHT02_RS06815	COG3695	enzyme binding
GHT02_RS06820	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GHT02_RS06825	COG1946	Acyl-CoA thioesterase
GHT02_RS06830	COG0004	ammonium transporteR
GHT02_RS06835	COG0347	Belongs to the P(II) protein family
GHT02_RS06840	COG1132	(ABC) transporter
GHT02_RS06845	COG1132	(ABC) transporter
GHT02_RS06850	COG1522	sequence-specific DNA binding
GHT02_RS06860	COG4533	DNA binding
GHT02_RS06870	COG0824	Thioesterase
GHT02_RS06875	COG1555	photosystem II stabilization
GHT02_RS06880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GHT02_RS06885	COG0776	regulation of translation
GHT02_RS06890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GHT02_RS06910	COG0271	Belongs to the BolA IbaG family
GHT02_RS06915	COG3056	Lipoprotein
GHT02_RS06920	COG2223	nitrite transmembrane transporter activity
GHT02_RS06925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GHT02_RS06930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GHT02_RS06935	COG1845	cytochrome c oxidase, subunit III
GHT02_RS06940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GHT02_RS06965	COG2814	Major facilitator Superfamily
GHT02_RS06975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GHT02_RS06980	COG0693	protein deglycase activity
GHT02_RS06995	COG0142	geranyltranstransferase activity
GHT02_RS07005	COG0667	Aldo Keto reductase
GHT02_RS07010	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GHT02_RS07015	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GHT02_RS07030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GHT02_RS07030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GHT02_RS07040	COG4238	major outer membrane lipoprotein
GHT02_RS07045	COG3248	Nucleoside-binding outer membrane protein
GHT02_RS07050	COG1403	HNH endonuclease
GHT02_RS07055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GHT02_RS07060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GHT02_RS07065	COG1862	Preprotein translocase
GHT02_RS07085	COG0366	Alpha amylase catalytic
GHT02_RS07090	COG1113	amino acid transport
GHT02_RS07095	COG1114	Component of the transport system for branched-chain amino acids
GHT02_RS07100	COG5002	protein histidine kinase activity
GHT02_RS07105	COG0745	RESPONSE REGULATOR receiver
GHT02_RS07110	COG0420	3'-5' exonuclease activity
GHT02_RS07115	COG0419	ATPase involved in DNA repair
GHT02_RS07120	COG2814	Major facilitator Superfamily
GHT02_RS07125	COG1940	carbohydrate kinase activity
GHT02_RS07145	COG4126	flavin adenine dinucleotide binding
GHT02_RS07165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GHT02_RS07170	COG3706	GGDEF domain
GHT02_RS07180	COG1785	Belongs to the alkaline phosphatase family
GHT02_RS07195	COG1181	Belongs to the D-alanine--D-alanine ligase family
GHT02_RS07215	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GHT02_RS07220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GHT02_RS07225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GHT02_RS07230	COG3468	outer membrane autotransporter barrel domain protein
GHT02_RS07235	COG0113	porphobilinogen synthase activity
GHT02_RS07240	COG2175	clavaminate synthase activity
GHT02_RS07245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GHT02_RS07255	COG4521	taurine ABC transporter
GHT02_RS07260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GHT02_RS07265	COG1215	transferase activity, transferring glycosyl groups
GHT02_RS07295	COG3122	Protein conserved in bacteria
GHT02_RS07300	COG2814	Major facilitator Superfamily
GHT02_RS07335	COG1414	Transcriptional regulator
GHT02_RS07340	COG1609	Transcriptional regulator
GHT02_RS07350	COG2223	nitrite transmembrane transporter activity
GHT02_RS07355	COG2807	transmembrane transport
GHT02_RS07365	COG0288	reversible hydration of carbon dioxide
GHT02_RS07370	COG0583	DNA-binding transcription factor activity
GHT02_RS07375	COG0402	S-adenosylhomocysteine deaminase activity
GHT02_RS07380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GHT02_RS07385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GHT02_RS07390	COG2079	MmgE PrpD family protein
GHT02_RS07395	COG0372	Belongs to the citrate synthase family
GHT02_RS07400	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GHT02_RS07405	COG3829	transcription factor binding
GHT02_RS07415	COG1280	lysine exporter protein (LysE YggA)
GHT02_RS07430	COG1064	alcohol dehydrogenase
GHT02_RS07440	COG1172	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS07445	COG1129	ABC transporter
GHT02_RS07450	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS07460	COG0402	S-adenosylhomocysteine deaminase activity
GHT02_RS07465	COG0549	Belongs to the carbamate kinase family
GHT02_RS07470	COG1304	FMN binding
GHT02_RS07475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GHT02_RS07485	COG0666	response to abiotic stimulus
GHT02_RS07495	COG0583	DNA-binding transcription factor activity
GHT02_RS07500	COG2200	EAL domain
GHT02_RS07500	COG2771	luxR family
GHT02_RS07510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GHT02_RS07535	COG1556	Lactate utilization protein
GHT02_RS07540	COG1139	Iron-sulfur cluster binding protein
GHT02_RS07545	COG0247	lactate metabolic process
GHT02_RS07550	COG2207	Transcriptional regulator
GHT02_RS07555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GHT02_RS07565	COG3059	membrane
GHT02_RS07570	COG0656	L-ascorbic acid biosynthetic process
GHT02_RS07575	COG2207	Transcriptional regulator
GHT02_RS07575	COG3708	Transcriptional regulator
GHT02_RS07580	COG1388	LysM domain
GHT02_RS07620	COG3188	usher protein
GHT02_RS07630	COG3121	Chaperone
GHT02_RS07635	COG0727	PFAM Uncharacterised protein family (UPF0153)
GHT02_RS07640	COG3477	response to acidic pH
GHT02_RS07645	COG2080	2 iron, 2 sulfur cluster binding
GHT02_RS07650	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GHT02_RS07655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GHT02_RS07660	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GHT02_RS07760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GHT02_RS07780	COG2195	Cleaves the N-terminal amino acid of tripeptides
GHT02_RS07785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GHT02_RS07790	COG1690	Belongs to the RtcB family
GHT02_RS07795	COG0454	-acetyltransferase
GHT02_RS07825	COG0791	NLP P60 protein
GHT02_RS07830	COG3077	Addiction module antitoxin, RelB DinJ family
GHT02_RS07835	COG3041	Addiction module toxin RelE StbE family
GHT02_RS07840	COG3034	peptidoglycan biosynthetic process
GHT02_RS07845	COG0121	glutamine amidotransferase
GHT02_RS07855	COG1960	acyl-CoA dehydrogenase activity
GHT02_RS07865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GHT02_RS07880	COG3209	COG3209 Rhs family protein
GHT02_RS07975	COG3157	Type VI secretion system effector, Hcp
GHT02_RS07980	COG4104	PAAR repeat-containing protein
GHT02_RS08000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHT02_RS08010	COG2226	methyltransferase
GHT02_RS08020	COG1388	LysM domain
GHT02_RS08020	COG0741	lytic transglycosylase activity
GHT02_RS08025	COG2226	methyltransferase
GHT02_RS08035	COG0583	DNA-binding transcription factor activity
GHT02_RS08040	COG0656	L-ascorbic acid biosynthetic process
GHT02_RS08075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GHT02_RS08080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GHT02_RS08085	COG2011	ABC-type metal ion transport system permease component
GHT02_RS08090	COG1464	Belongs to the NlpA lipoprotein family
GHT02_RS08100	COG1720	tRNA m6t6A37 methyltransferase activity
GHT02_RS08110	COG0791	NLP P60 protein
GHT02_RS08115	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS08120	COG0564	pseudouridine synthase activity
GHT02_RS08130	COG0417	DNA replication proofreading
GHT02_RS08135	COG0235	Class ii aldolase
GHT02_RS08150	COG4977	sequence-specific DNA binding
GHT02_RS08155	COG0586	Pfam SNARE associated Golgi protein
GHT02_RS08165	COG1178	ABC-type Fe3 transport system permease component
GHT02_RS08170	COG4143	(ABC) transporter
GHT02_RS08185	COG2814	Major facilitator Superfamily
GHT02_RS08200	COG0473	3-isopropylmalate dehydrogenase activity
GHT02_RS08215	COG0583	DNA-binding transcription factor activity
GHT02_RS08225	COG0028	Belongs to the TPP enzyme family
GHT02_RS08230	COG0440	acetolactate synthase activity
GHT02_RS08240	COG1609	Transcriptional regulator
GHT02_RS08255	COG3116	cell division
GHT02_RS08260	COG0768	penicillin binding
GHT02_RS08265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHT02_RS08270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GHT02_RS08285	COG0772	Belongs to the SEDS family
GHT02_RS08300	COG1181	Belongs to the D-alanine--D-alanine ligase family
GHT02_RS08305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GHT02_RS08310	COG0849	cell division
GHT02_RS08315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GHT02_RS08335	COG0494	nUDIX hydrolase
GHT02_RS08350	COG0237	dephospho-CoA kinase activity
GHT02_RS08365	COG1459	type II secretion system
GHT02_RS08375	COG4969	Belongs to the N-Me-Phe pilin family
GHT02_RS08380	COG0157	Belongs to the NadC ModD family
GHT02_RS08385	COG3023	N-Acetylmuramoyl-L-alanine amidase
GHT02_RS08390	COG3725	Membrane protein required for beta-lactamase induction
GHT02_RS08395	COG1113	amino acid transport
GHT02_RS08400	COG2186	Transcriptional regulator
GHT02_RS08405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GHT02_RS08410	COG0508	dehydrogenase complex catalyzes the overall conversion of
GHT02_RS08415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GHT02_RS08420	COG3064	Membrane
GHT02_RS08425	COG1049	propionate catabolic process, 2-methylcitrate cycle
GHT02_RS08450	COG2132	Multicopper oxidase
GHT02_RS08455	COG4993	Dehydrogenase
GHT02_RS08460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GHT02_RS08465	COG0288	reversible hydration of carbon dioxide
GHT02_RS08470	COG1131	(ABC) transporter
GHT02_RS08475	COG0842	Transport permease protein
GHT02_RS08480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS08485	COG0726	polysaccharide deacetylase
GHT02_RS08495	COG5464	transposase or invertase
GHT02_RS08500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GHT02_RS08510	COG3539	Fimbrial protein
GHT02_RS08515	COG3539	Fimbrial protein
GHT02_RS08520	COG3539	Fimbrial protein
GHT02_RS08525	COG3539	Fimbrial protein
GHT02_RS08530	COG3188	usher protein
GHT02_RS08535	COG3121	Chaperone
GHT02_RS08540	COG3539	Fimbrial protein
GHT02_RS08545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GHT02_RS08550	COG0617	tRNA 3'-terminal CCA addition
GHT02_RS08560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GHT02_RS08570	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GHT02_RS08575	COG1643	Atp-dependent helicase
GHT02_RS08580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GHT02_RS08585	COG4774	siderophore transport
GHT02_RS08590	COG1120	ATPase activity
GHT02_RS08595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GHT02_RS08600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GHT02_RS08625	COG2860	membrane
GHT02_RS08630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GHT02_RS08645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GHT02_RS08650	COG3835	regulator
GHT02_RS08670	COG0024	Methionine aminopeptidase
GHT02_RS08695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GHT02_RS08700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GHT02_RS08705	COG0575	Belongs to the CDS family
GHT02_RS08710	COG0750	zinc metalloprotease
GHT02_RS08720	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GHT02_RS08725	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GHT02_RS08750	COG0587	DNA-directed DNA polymerase activity
GHT02_RS08760	COG1982	Orn Lys Arg decarboxylase major
GHT02_RS08765	COG0346	lactoylglutathione lyase activity
GHT02_RS08775	COG4568	rho-dependent transcription termination
GHT02_RS08785	COG4681	YaeQ
GHT02_RS08790	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GHT02_RS08795	COG3015	lipoprotein NlpE involved in copper resistance
GHT02_RS08800	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS08805	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GHT02_RS08810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GHT02_RS08815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GHT02_RS08840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GHT02_RS08855	COG2271	Major facilitator Superfamily
GHT02_RS08860	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GHT02_RS08865	COG0644	oxidoreductase
GHT02_RS08915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GHT02_RS08920	COG0505	Belongs to the CarA family
GHT02_RS08940	COG1047	Peptidyl-prolyl cis-trans
GHT02_RS08955	COG0196	riboflavin kinase activity
GHT02_RS08985	COG0583	DNA-binding transcription factor activity
GHT02_RS09015	COG4735	regulation of single-species biofilm formation
GHT02_RS09020	COG1584	GPR1 FUN34 yaaH family protein
GHT02_RS09025	COG0521	Mo-molybdopterin cofactor biosynthetic process
GHT02_RS09035	COG1115	amino acid carrier protein
GHT02_RS09045	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS09055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GHT02_RS09065	COG0460	homoserine dehydrogenase
GHT02_RS09065	COG0527	aspartate kinase activity
GHT02_RS09075	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GHT02_RS09085	COG2826	transposase and inactivated derivatives, IS30 family
GHT02_RS09090	COG0745	RESPONSE REGULATOR receiver
GHT02_RS09095	COG4452	Inner membrane protein CreD
GHT02_RS09100	COG2205	protein histidine kinase activity
GHT02_RS09105	COG0745	RESPONSE REGULATOR receiver
GHT02_RS09110	COG3045	CreA protein
GHT02_RS09115	COG3708	Transcriptional regulator
GHT02_RS09115	COG2207	Transcriptional regulator
GHT02_RS09135	COG0741	lytic transglycosylase activity
GHT02_RS09140	COG0488	(ABC) transporter
GHT02_RS09145	COG3172	ATPase kinase involved in NAD metabolism
GHT02_RS09145	COG1056	cytidyltransferase-related domain
GHT02_RS09150	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GHT02_RS09155	COG0560	Phosphoserine phosphatase
GHT02_RS09160	COG3726	membrane protein affecting hemolysin expression
GHT02_RS09195	COG1328	CTP reductase activity
GHT02_RS09200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHT02_RS09205	COG0084	hydrolase, TatD family'
GHT02_RS09210	COG4667	esterase of the alpha-beta hydrolase superfamily
GHT02_RS09220	COG2823	Periplasmic or secreted lipoprotein
GHT02_RS09230	COG1011	Hydrolase
GHT02_RS09235	COG0456	acetyltransferase
GHT02_RS09240	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GHT02_RS09270	COG4114	ferric iron reductase
GHT02_RS09275	COG2197	response regulator
GHT02_RS09280	COG2197	response regulator
GHT02_RS09285	COG2966	Psort location CytoplasmicMembrane, score
GHT02_RS09300	COG1484	DNA-dependent DNA replication
GHT02_RS09315	COG1063	alcohol dehydrogenase
GHT02_RS09320	COG1802	Transcriptional regulator
GHT02_RS09325	COG2271	Major facilitator Superfamily
GHT02_RS09330	COG0840	transmembrane signaling receptor activity
GHT02_RS09335	COG1846	Transcriptional regulator
GHT02_RS09340	COG0179	Fumarylacetoacetate (FAA) hydrolase
GHT02_RS09345	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS09350	COG3384	dioxygenase
GHT02_RS09360	COG3971	2-oxopent-4-enoate hydratase activity
GHT02_RS09380	COG2368	4-hydroxyphenylacetate
GHT02_RS09385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GHT02_RS09390	COG1966	Carbon starvation protein
GHT02_RS09395	COG2879	small protein
GHT02_RS09400	COG0523	cobalamin synthesis protein
GHT02_RS09410	COG5457	Domain of unknown function (DUF1127)
GHT02_RS09415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GHT02_RS09425	COG2814	Major facilitator Superfamily
GHT02_RS09430	COG2733	membrane
GHT02_RS09435	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GHT02_RS09440	COG1924	4 iron, 4 sulfur cluster binding
GHT02_RS09455	COG0477	Major facilitator Superfamily
GHT02_RS09465	COG3366	ferrous iron transmembrane transporter activity
GHT02_RS09470	COG0700	Nucleoside recognition
GHT02_RS09475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GHT02_RS09480	COG0583	DNA-binding transcription factor activity
GHT02_RS09500	COG2186	Transcriptional regulator
GHT02_RS09505	COG0246	Mannitol dehydrogenase
GHT02_RS09515	COG2610	gluconate transmembrane transporter activity
GHT02_RS09520	COG3539	Fimbrial protein
GHT02_RS09525	COG3539	Fimbrial protein
GHT02_RS09530	COG3539	Fimbrial protein
GHT02_RS09535	COG3188	usher protein
GHT02_RS09540	COG3121	Chaperone
GHT02_RS09545	COG3539	Fimbrial protein
GHT02_RS09555	COG4974	Belongs to the 'phage' integrase family
GHT02_RS09560	COG0582	viral genome integration into host DNA
GHT02_RS09565	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GHT02_RS09590	COG1401	restriction endodeoxyribonuclease activity
GHT02_RS09645	COG2815	serine threonine protein kinase
GHT02_RS09645	COG0515	serine threonine protein kinase
GHT02_RS09650	COG0582	viral genome integration into host DNA
GHT02_RS09700	COG1064	alcohol dehydrogenase
GHT02_RS09705	COG3265	gluconokinase activity
GHT02_RS09710	COG1063	alcohol dehydrogenase
GHT02_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS09720	COG2610	gluconate transmembrane transporter activity
GHT02_RS09725	COG1609	Transcriptional regulator
GHT02_RS09730	COG0433	COG0433 Predicted ATPase
GHT02_RS09735	COG0795	lipopolysaccharide-transporting ATPase activity
GHT02_RS09740	COG0795	lipopolysaccharide-transporting ATPase activity
GHT02_RS09750	COG2927	DNA polymerase III (CHI subunit)
GHT02_RS09755	COG0525	valine-tRNA ligase activity
GHT02_RS09760	COG4269	membrane
GHT02_RS09765	COG0456	acetyltransferase
GHT02_RS09770	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GHT02_RS09790	COG2731	YhcH YjgK YiaL family protein
GHT02_RS09795	COG1309	transcriptional regulator
GHT02_RS09800	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS09805	COG0251	oxidation-reduction process
GHT02_RS09825	COG0251	oxidation-reduction process
GHT02_RS09830	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS09835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GHT02_RS09845	COG1609	Transcriptional regulator
GHT02_RS09850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS09850	COG1263	PTS System
GHT02_RS09855	COG0366	Alpha amylase catalytic
GHT02_RS09860	COG1328	CTP reductase activity
GHT02_RS09865	COG0602	queuosine metabolic process
GHT02_RS09870	COG3783	Cytochrome b(562)
GHT02_RS09875	COG0312	modulator of DNA gyrase
GHT02_RS09885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GHT02_RS09895	COG1172	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS09900	COG1172	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS09905	COG1129	ABC transporter
GHT02_RS09910	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS09915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GHT02_RS09920	COG2337	Toxic component of a toxin-antitoxin (TA) module
GHT02_RS09925	COG2336	PFAM SpoVT AbrB
GHT02_RS09930	COG2105	PFAM AIG2 family protein
GHT02_RS09935	COG2911	Protein conserved in bacteria
GHT02_RS09940	COG0729	surface antigen
GHT02_RS09950	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS09955	COG1253	flavin adenine dinucleotide binding
GHT02_RS09965	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GHT02_RS09970	COG1218	3'(2'),5'-bisphosphate nucleotidase
GHT02_RS09975	COG0737	Belongs to the 5'-nucleotidase family
GHT02_RS09980	COG1733	regulation of RNA biosynthetic process
GHT02_RS09985	COG0702	epimerase
GHT02_RS09990	COG0697	spore germination
GHT02_RS10000	COG1113	amino acid transport
GHT02_RS10005	COG0545	Peptidyl-prolyl cis-trans isomerase
GHT02_RS10010	COG3061	Opacity-associated protein A
GHT02_RS10020	COG0675	Transposase, IS605 OrfB family
GHT02_RS10045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GHT02_RS10065	COG3477	response to acidic pH
GHT02_RS10095	COG3037	sugar-specific permease SgaT UlaA
GHT02_RS10110	COG1073	alpha beta
GHT02_RS10115	COG3650	response to hydrogen peroxide
GHT02_RS10125	COG1960	acyl-CoA dehydrogenase activity
GHT02_RS10130	COG0754	glutathionylspermidine amidase activity
GHT02_RS10135	COG5463	Belongs to the UPF0441 family
GHT02_RS10140	COG3766	membrane
GHT02_RS10150	COG1842	Phage shock protein A
GHT02_RS10155	COG3789	protein conserved in bacteria
GHT02_RS10160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHT02_RS10165	COG0557	exoribonuclease II activity
GHT02_RS10180	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GHT02_RS10185	COG0330	HflC and HflK could
GHT02_RS10190	COG0330	HflC and HflK could
GHT02_RS10195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GHT02_RS10215	COG0860	N-Acetylmuramoyl-L-alanine amidase
GHT02_RS10220	COG0802	atpase or kinase
GHT02_RS10225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GHT02_RS10225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GHT02_RS10230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GHT02_RS10270	COG1511	domain protein
GHT02_RS10270	COG3264	Mechanosensitive ion channel
GHT02_RS10275	COG0531	amino acid
GHT02_RS10285	COG1053	succinate dehydrogenase
GHT02_RS10290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GHT02_RS10305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GHT02_RS10310	COG3040	lipid binding
GHT02_RS10315	COG2076	Multidrug Resistance protein
GHT02_RS10320	COG5510	response to toxic substance
GHT02_RS10325	COG5510	response to toxic substance
GHT02_RS10335	COG1509	lysine 2,3-aminomutase activity
GHT02_RS10360	COG0531	amino acid
GHT02_RS10365	COG3030	protein affecting phage T7 exclusion by the F plasmid
GHT02_RS10370	COG1027	Aspartate ammonia-lyase
GHT02_RS10375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GHT02_RS10385	COG4232	protein-disulfide reductase activity
GHT02_RS10390	COG1309	transcriptional regulator
GHT02_RS10400	COG0582	viral genome integration into host DNA
GHT02_RS10410	COG2194	sulfuric ester hydrolase activity
GHT02_RS10460	COG4372	Transposase
GHT02_RS10465	COG3436	PFAM IS66 Orf2 family protein
GHT02_RS10480	COG2207	Transcriptional regulator
GHT02_RS10500	COG3119	arylsulfatase activity
GHT02_RS10535	COG4771	TonB-dependent receptor
GHT02_RS10545	COG1475	DNA binding
GHT02_RS10555	COG3969	phosphoadenosine phosphosulfate
GHT02_RS10560	COG0668	transmembrane transport
GHT02_RS10590	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GHT02_RS10675	COG5295	Hep Hag repeat protein
GHT02_RS10675	COG5295	Hep Hag repeat protein
GHT02_RS10680	COG4771	TonB-dependent receptor
GHT02_RS10705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS10715	COG3037	sugar-specific permease SgaT UlaA
GHT02_RS10730	COG0738	Major facilitator superfamily
GHT02_RS10740	COG1349	DNA-binding transcription factor activity
GHT02_RS10835	COG3468	outer membrane autotransporter barrel domain protein
GHT02_RS10855	COG2003	Belongs to the UPF0758 family
GHT02_RS10890	COG3609	addiction module antidote protein, CC2985 family
GHT02_RS10900	COG3710	Transcriptional regulator
GHT02_RS10905	COG0531	amino acid
GHT02_RS10910	COG1982	Orn Lys Arg decarboxylase major
GHT02_RS10915	COG3104	oligopeptide transport
GHT02_RS10920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GHT02_RS10935	COG2388	GCN5-related N-acetyl-transferase
GHT02_RS10940	COG3592	Divergent 4Fe-4S mono-cluster
GHT02_RS10945	COG3290	protein histidine kinase activity
GHT02_RS10950	COG4565	transcriptional regulatory protein
GHT02_RS10955	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GHT02_RS10960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GHT02_RS10960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GHT02_RS10965	COG3647	Membrane
GHT02_RS10970	COG2211	Major facilitator Superfamily
GHT02_RS10975	COG1486	melibiose metabolic process
GHT02_RS10980	COG2169	Transcriptional regulator
GHT02_RS10985	COG1982	Orn Lys Arg decarboxylase major
GHT02_RS10990	COG2207	Transcriptional regulator
GHT02_RS10995	COG0531	amino acid
GHT02_RS11000	COG2194	sulfuric ester hydrolase activity
GHT02_RS11005	COG0745	RESPONSE REGULATOR receiver
GHT02_RS11010	COG0642	Histidine kinase
GHT02_RS11020	COG0477	Major facilitator Superfamily
GHT02_RS11035	COG2824	Alkylphosphonate utilization operon protein PhnA
GHT02_RS11040	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GHT02_RS11050	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GHT02_RS11055	COG3639	organic phosphonate transmembrane transporter activity
GHT02_RS11060	COG2188	Transcriptional regulator
GHT02_RS11065	COG3624	Phosphonate C-P lyase system protein PhnG
GHT02_RS11070	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GHT02_RS11075	COG3626	phosphonate metabolism
GHT02_RS11080	COG3627	carbon phosphorus lyase activity
GHT02_RS11085	COG4107	phosphonate C-P lyase system protein PhnK
GHT02_RS11095	COG4778	phosphonate C-P lyase system protein PhnL
GHT02_RS11100	COG3454	Phosphonate metabolism
GHT02_RS11105	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GHT02_RS11110	COG0456	acetyltransferase
GHT02_RS11115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GHT02_RS11125	COG0698	ribose 5-phosphate isomerase
GHT02_RS11130	COG1737	Transcriptional regulator
GHT02_RS11135	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS11140	COG1129	ABC transporter
GHT02_RS11145	COG1172	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS11150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GHT02_RS11155	COG1940	carbohydrate kinase activity
GHT02_RS11160	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GHT02_RS11170	COG1566	PFAM secretion protein HlyD family protein
GHT02_RS11175	COG1289	transmembrane transporter activity
GHT02_RS11190	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GHT02_RS11195	COG1301	dicarboxylic acid transport
GHT02_RS11200	COG4235	cytochrome complex assembly
GHT02_RS11205	COG3088	subunit of a heme lyase
GHT02_RS11210	COG1138	Cytochrome C-type biogenesis protein
GHT02_RS11215	COG3301	Polysulphide reductase, NrfD
GHT02_RS11220	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS11225	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GHT02_RS11235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GHT02_RS11240	COG3162	membrane
GHT02_RS11250	COG1357	PFAM Pentapeptide repeats (8 copies)
GHT02_RS11255	COG0025	NhaP-type Na H and K H
GHT02_RS11260	COG2252	PERMEase
GHT02_RS11265	COG0789	Transcriptional regulator
GHT02_RS11270	COG2207	Transcriptional regulator
GHT02_RS11275	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GHT02_RS11285	COG0629	single-stranded DNA binding
GHT02_RS11290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GHT02_RS11295	COG2315	Protein conserved in bacteria
GHT02_RS11300	COG0432	Pfam Uncharacterised protein family UPF0047
GHT02_RS11305	COG3700	Belongs to the class B bacterial acid phosphatase family
GHT02_RS11315	COG1448	Aminotransferase
GHT02_RS11320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GHT02_RS11325	COG0305	Participates in initiation and elongation during chromosome replication
GHT02_RS11330	COG0604	alcohol dehydrogenase
GHT02_RS11340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHT02_RS11350	COG0735	belongs to the Fur family
GHT02_RS11355	COG3237	CsbD-like
GHT02_RS11360	COG0534	Mate efflux family protein
GHT02_RS11370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GHT02_RS11405	COG3842	ATPase activity
GHT02_RS11410	COG2182	Extracellular solute-binding protein
GHT02_RS11415	COG1175	transmembrane transport
GHT02_RS11420	COG3833	ABC-type maltose transport systems, permease component
GHT02_RS11425	COG0477	Major facilitator Superfamily
GHT02_RS11425	COG2814	Major facilitator Superfamily
GHT02_RS11440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GHT02_RS11465	COG0527	aspartate kinase activity
GHT02_RS11470	COG0542	response to heat
GHT02_RS11475	COG3541	Predicted nucleotidyltransferase
GHT02_RS11490	COG1187	pseudouridine synthase activity
GHT02_RS11500	COG1283	sodium-dependent phosphate transmembrane transporter activity
GHT02_RS11505	COG1410	methionine synthase
GHT02_RS11505	COG0646	methionine synthase
GHT02_RS11510	COG1414	Transcriptional regulator
GHT02_RS11525	COG2224	Isocitrate lyase
GHT02_RS11530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GHT02_RS11540	COG0456	acetyltransferase
GHT02_RS11570	COG0151	Belongs to the GarS family
GHT02_RS11575	COG2204	response regulator
GHT02_RS11580	COG4191	Histidine kinase
GHT02_RS11585	COG3678	ATP-independent chaperone mediated protein folding
GHT02_RS11600	COG3068	Protein conserved in bacteria
GHT02_RS11635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GHT02_RS11640	COG2104	thiamine diphosphate biosynthetic process
GHT02_RS11650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GHT02_RS11690	COG0250	Participates in transcription elongation, termination and antitermination
GHT02_RS11695	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GHT02_RS11730	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GHT02_RS11730	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GHT02_RS11780	COG1309	transcriptional regulator
GHT02_RS11790	COG0583	DNA-binding transcription factor activity
GHT02_RS11795	COG2271	Major facilitator Superfamily
GHT02_RS11800	COG4948	Mandelate Racemase Muconate Lactonizing
GHT02_RS11815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GHT02_RS11830	COG2194	sulfuric ester hydrolase activity
GHT02_RS11835	COG2207	Transcriptional regulator
GHT02_RS11840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS11845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHT02_RS11850	COG1882	Formate acetyltransferase
GHT02_RS11855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS11860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS11865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHT02_RS11865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS11865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS11870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GHT02_RS11875	COG0371	Dehydrogenase
GHT02_RS11880	COG3738	Protein conserved in bacteria
GHT02_RS11885	COG0697	spore germination
GHT02_RS11895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GHT02_RS11900	COG0527	aspartate kinase activity
GHT02_RS11900	COG0460	homoserine dehydrogenase
GHT02_RS11905	COG0626	cystathionine gamma-synthase activity
GHT02_RS11915	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS11920	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GHT02_RS11935	COG3209	COG3209 Rhs family protein
GHT02_RS11945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHT02_RS11950	COG1609	Transcriptional regulator
GHT02_RS11955	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GHT02_RS11970	COG1575	Belongs to the MenA family. Type 1 subfamily
GHT02_RS11985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GHT02_RS11995	COG1494	fructose-1,6-bisphosphatase
GHT02_RS12005	COG0589	response to stress
GHT02_RS12010	COG3691	Protein conserved in bacteria
GHT02_RS12015	COG3152	Membrane
GHT02_RS12035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GHT02_RS12050	COG3678	ATP-independent chaperone mediated protein folding
GHT02_RS12055	COG0745	RESPONSE REGULATOR receiver
GHT02_RS12060	COG2205	protein histidine kinase activity
GHT02_RS12065	COG2258	MOSC domain
GHT02_RS12075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GHT02_RS12115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS12120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS12120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS12125	COG1363	Peptidase, m42
GHT02_RS12130	COG3711	transcriptional antiterminator
GHT02_RS12130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS12150	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS12155	COG2864	formate dehydrogenase
GHT02_RS12175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GHT02_RS12180	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GHT02_RS12200	COG0456	acetyltransferase
GHT02_RS12215	COG1011	Hydrolase
GHT02_RS12225	COG0477	Major facilitator Superfamily
GHT02_RS12235	COG1063	alcohol dehydrogenase
GHT02_RS12240	COG3684	Belongs to the aldolase LacD family
GHT02_RS12245	COG2084	Dehydrogenase
GHT02_RS12255	COG1349	DNA-binding transcription factor activity
GHT02_RS12260	COG2271	Major facilitator Superfamily
GHT02_RS12265	COG1082	Xylose isomerase domain protein TIM barrel
GHT02_RS12270	COG2188	Transcriptional regulator
GHT02_RS12275	COG1217	gtp-binding protein TYPA
GHT02_RS12280	COG0174	glutamine synthetase
GHT02_RS12285	COG3852	Histidine kinase
GHT02_RS12290	COG2204	response regulator
GHT02_RS12300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GHT02_RS12315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GHT02_RS12315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GHT02_RS12320	COG0204	Acyl-transferase
GHT02_RS12325	COG5339	Protein conserved in bacteria
GHT02_RS12330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GHT02_RS12335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GHT02_RS12340	COG3084	Protein conserved in bacteria
GHT02_RS12345	COG0746	molybdenum cofactor guanylyltransferase activity
GHT02_RS12350	COG1763	Mo-molybdopterin cofactor biosynthetic process
GHT02_RS12380	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GHT02_RS12385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GHT02_RS12390	COG1739	Uncharacterized protein family UPF0029
GHT02_RS12410	COG0543	2 iron, 2 sulfur cluster binding
GHT02_RS12415	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GHT02_RS12420	COG0250	Participates in transcription elongation, termination and antitermination
GHT02_RS12430	COG0805	protein transport
GHT02_RS12435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GHT02_RS12440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GHT02_RS12450	COG3165	ubiquinone biosynthetic process from chorismate
GHT02_RS12460	COG1322	Protein conserved in bacteria
GHT02_RS12465	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GHT02_RS12470	COG0412	Dienelactone hydrolase
GHT02_RS12480	COG0583	DNA-binding transcription factor activity
GHT02_RS12485	COG0697	spore germination
GHT02_RS12490	COG0561	phosphatase activity
GHT02_RS12495	COG2267	carboxylic ester hydrolase activity
GHT02_RS12500	COG1280	lysine exporter protein (LysE YggA)
GHT02_RS12505	COG1280	lysine exporter protein (LysE YggA)
GHT02_RS12510	COG0514	ATP-dependent DNA helicase (RecQ)
GHT02_RS12515	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GHT02_RS12520	COG2050	protein possibly involved in aromatic compounds catabolism
GHT02_RS12525	COG2962	Rard protein
GHT02_RS12550	COG0598	Magnesium transport protein CorA
GHT02_RS12555	COG3698	Phosphodiester glycosidase
GHT02_RS12560	COG0210	DNA helicase
GHT02_RS12565	COG1011	Hydrolase
GHT02_RS12575	COG3159	Protein conserved in bacteria
GHT02_RS12585	COG5567	small periplasmic lipoprotein
GHT02_RS12610	COG3072	Adenylate cyclase
GHT02_RS12620	COG1587	Uroporphyrinogen-III synthase
GHT02_RS12625	COG2959	enzyme of heme biosynthesis
GHT02_RS12630	COG3071	HemY protein
GHT02_RS12635	COG3119	arylsulfatase activity
GHT02_RS12640	COG0641	radical SAM
GHT02_RS12665	COG1113	amino acid transport
GHT02_RS12680	COG2826	transposase and inactivated derivatives, IS30 family
GHT02_RS12690	COG2244	polysaccharide biosynthetic process
GHT02_RS12695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GHT02_RS12700	COG0456	acetyltransferase
GHT02_RS12705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GHT02_RS12710	COG1088	dTDP-glucose 4,6-dehydratase activity
GHT02_RS12715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GHT02_RS12720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GHT02_RS12725	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GHT02_RS12730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GHT02_RS12735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GHT02_RS12745	COG3118	belongs to the thioredoxin family
GHT02_RS12760	COG0210	DNA helicase
GHT02_RS12765	COG3692	DNA binding
GHT02_RS12770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GHT02_RS12780	COG0583	DNA-binding transcription factor activity
GHT02_RS12785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GHT02_RS12795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GHT02_RS12800	COG3978	acetolactate synthase activity
GHT02_RS12820	COG0606	chelatase, subunit chli
GHT02_RS12825	COG3085	chromosome segregation
GHT02_RS12865	COG2186	Transcriptional regulator
GHT02_RS12870	COG0477	Major facilitator Superfamily
GHT02_RS12875	COG1609	Transcriptional regulator
GHT02_RS12880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHT02_RS12885	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS12890	COG1172	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS12895	COG1129	ABC transporter
GHT02_RS12925	COG1522	sequence-specific DNA binding
GHT02_RS12930	COG0716	FMN binding
GHT02_RS12945	COG3312	ion transport
GHT02_RS12995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GHT02_RS13010	COG3188	usher protein
GHT02_RS13020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GHT02_RS13025	COG0573	inorganic phosphate transmembrane transporter activity
GHT02_RS13030	COG0581	inorganic phosphate transmembrane transporter activity
GHT02_RS13035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GHT02_RS13040	COG0704	Plays a role in the regulation of phosphate uptake
GHT02_RS13045	COG3711	transcriptional antiterminator
GHT02_RS13050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS13050	COG2190	(PTS) system
GHT02_RS13050	COG1263	PTS System
GHT02_RS13055	COG2723	6-phospho-beta-galactosidase activity
GHT02_RS13065	COG2382	esterase
GHT02_RS13070	COG0363	glucosamine-6-phosphate deaminase activity
GHT02_RS13075	COG3196	Protein conserved in bacteria
GHT02_RS13085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GHT02_RS13090	COG2252	PERMEase
GHT02_RS13095	COG0431	NADPH-dependent FMN reductase
GHT02_RS13100	COG2091	lysine biosynthetic process via aminoadipic acid
GHT02_RS13115	COG0814	amino acid
GHT02_RS13165	COG0592	DNA-directed DNA polymerase activity
GHT02_RS13175	COG0187	DNA topoisomerase II activity
GHT02_RS13180	COG3753	Protein conserved in bacteria
GHT02_RS13185	COG0561	phosphatase activity
GHT02_RS13195	COG2186	Transcriptional regulator
GHT02_RS13200	COG3734	2-keto-3-deoxy-galactonokinase
GHT02_RS13205	COG0800	Aldolase
GHT02_RS13215	COG2271	Major facilitator Superfamily
GHT02_RS13225	COG0823	Involved in the tonB-independent uptake of proteins
GHT02_RS13230	COG5645	(Lipo)protein
GHT02_RS13250	COG2188	Transcriptional regulator
GHT02_RS13265	COG2207	Transcriptional regulator
GHT02_RS13270	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GHT02_RS13275	COG3119	arylsulfatase activity
GHT02_RS13285	COG3119	arylsulfatase activity
GHT02_RS13295	COG2149	membrane
GHT02_RS13305	COG0641	radical SAM
GHT02_RS13310	COG2814	Major facilitator Superfamily
GHT02_RS13325	COG0028	Belongs to the TPP enzyme family
GHT02_RS13330	COG0440	acetolactate synthase activity
GHT02_RS13335	COG2197	response regulator
GHT02_RS13340	COG3851	Histidine kinase
GHT02_RS13345	COG2271	Major facilitator Superfamily
GHT02_RS13350	COG2271	Major facilitator Superfamily
GHT02_RS13360	COG2252	PERMEase
GHT02_RS13380	COG1464	Belongs to the NlpA lipoprotein family
GHT02_RS13385	COG0697	spore germination
GHT02_RS13390	COG2814	Major facilitator Superfamily
GHT02_RS13435	COG2003	Belongs to the UPF0758 family
GHT02_RS13465	COG2020	methyltransferase activity
GHT02_RS13470	COG3468	outer membrane autotransporter barrel domain protein
GHT02_RS13480	COG4983	Phage plasmid primase, P4 family domain protein
GHT02_RS13580	COG2994	toxin metabolic process
GHT02_RS13800	COG2826	transposase and inactivated derivatives, IS30 family
GHT02_RS13830	COG3037	sugar-specific permease SgaT UlaA
GHT02_RS13840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS13845	COG1609	Transcriptional regulator
GHT02_RS13865	COG4771	TonB-dependent receptor
GHT02_RS13875	COG2207	Transcriptional regulator
GHT02_RS13905	COG0582	viral genome integration into host DNA
GHT02_RS13915	COG2211	Major facilitator Superfamily
GHT02_RS13920	COG1501	Belongs to the glycosyl hydrolase 31 family
GHT02_RS13925	COG2982	Protein involved in outer membrane biogenesis
GHT02_RS13930	COG2233	PERMEase
GHT02_RS13935	COG0786	glutamate:sodium symporter activity
GHT02_RS13945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GHT02_RS13950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHT02_RS13955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GHT02_RS13965	COG0194	GDP metabolic process
GHT02_RS13975	COG2860	membrane
GHT02_RS13980	COG3645	SOS response
GHT02_RS13985	COG1561	YicC-like family, N-terminal region
GHT02_RS14010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GHT02_RS14040	COG1519	Transferase
GHT02_RS14045	COG0859	PFAM glycosyl transferase family 9
GHT02_RS14050	COG0438	transferase activity, transferring glycosyl groups
GHT02_RS14055	COG0515	serine threonine protein kinase
GHT02_RS14065	COG3642	lipopolysaccharide core region biosynthetic process
GHT02_RS14085	COG0859	PFAM glycosyl transferase family 9
GHT02_RS14090	COG0859	PFAM glycosyl transferase family 9
GHT02_RS14105	COG0156	8-amino-7-oxononanoate synthase activity
GHT02_RS14115	COG1216	Glycosyl transferase, family 2
GHT02_RS14120	COG2861	carbohydrate metabolic process
GHT02_RS14125	COG4942	peptidase
GHT02_RS14135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHT02_RS14140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GHT02_RS14155	COG1045	serine acetyltransferase
GHT02_RS14160	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GHT02_RS14170	COG2186	Transcriptional regulator
GHT02_RS14175	COG1620	l-lactate permease
GHT02_RS14180	COG5295	Hep Hag repeat protein
GHT02_RS14200	COG3722	fumarate hydratase activity
GHT02_RS14210	COG2213	PTS system mannitol-specific
GHT02_RS14210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS14220	COG1566	PFAM secretion protein HlyD family protein
GHT02_RS14225	COG0625	glutathione transferase activity
GHT02_RS14235	COG3276	selenocysteine insertion sequence binding
GHT02_RS14240	COG1454	alcohol dehydrogenase
GHT02_RS14245	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS14255	COG1598	PFAM Uncharacterised protein family UPF0150
GHT02_RS14265	COG2211	Major facilitator Superfamily
GHT02_RS14275	COG0235	Class ii aldolase
GHT02_RS14280	COG3623	hexulose-6-phosphate isomerase
GHT02_RS14285	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GHT02_RS14290	COG1070	Carbohydrate kinase
GHT02_RS14295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GHT02_RS14300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GHT02_RS14305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GHT02_RS14310	COG2731	YhcH YjgK YiaL family protein
GHT02_RS14320	COG1414	Transcriptional regulator
GHT02_RS14325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS14330	COG3977	Valine--pyruvate aminotransferase
GHT02_RS14335	COG0366	Alpha amylase catalytic
GHT02_RS14340	COG2992	FlgJ-related protein
GHT02_RS14345	COG1609	Transcriptional regulator
GHT02_RS14345	COG2207	Transcriptional regulator
GHT02_RS14350	COG4214	carbohydrate transport
GHT02_RS14360	COG4213	ABC transporter substrate-binding protein
GHT02_RS14370	COG1070	Carbohydrate kinase
GHT02_RS14375	COG4682	membrane
GHT02_RS14380	COG4682	membrane
GHT02_RS14385	COG3274	enterobacterial common antigen metabolic process
GHT02_RS14410	COG1278	Cold shock
GHT02_RS14415	COG2944	sequence-specific DNA binding
GHT02_RS14430	COG2885	chlorophyll binding
GHT02_RS14435	COG0243	molybdopterin cofactor binding
GHT02_RS14440	COG0456	acetyltransferase
GHT02_RS14445	COG2818	Glycosylase
GHT02_RS14450	COG5571	outer membrane autotransporter
GHT02_RS14460	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS14495	COG2194	sulfuric ester hydrolase activity
GHT02_RS14510	COG0747	negative chemotaxis
GHT02_RS14515	COG0601	transmembrane transport
GHT02_RS14520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GHT02_RS14525	COG0444	Belongs to the ABC transporter superfamily
GHT02_RS14530	COG4608	Belongs to the ABC transporter superfamily
GHT02_RS14535	COG0814	amino acid
GHT02_RS14555	COG2194	sulfuric ester hydrolase activity
GHT02_RS14580	COG1215	transferase activity, transferring glycosyl groups
GHT02_RS14585	COG1215	transferase activity, transferring glycosyl groups
GHT02_RS14590	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GHT02_RS14595	COG0457	Tetratricopeptide repeat
GHT02_RS14595	COG3118	belongs to the thioredoxin family
GHT02_RS14600	COG2200	EAL domain
GHT02_RS14600	COG2199	diguanylate cyclase activity
GHT02_RS14610	COG0612	Peptidase, M16
GHT02_RS14620	COG2200	EAL domain
GHT02_RS14625	COG2982	Protein involved in outer membrane biogenesis
GHT02_RS14630	COG0477	Major facilitator Superfamily
GHT02_RS14635	COG1295	ribonuclease BN
GHT02_RS14640	COG0583	DNA-binding transcription factor activity
GHT02_RS14655	COG1858	cytochrome C peroxidase
GHT02_RS14660	COG0076	glutamate decarboxylase activity
GHT02_RS14670	COG2207	Transcriptional regulator
GHT02_RS14675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GHT02_RS14680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS14690	COG2771	luxR family
GHT02_RS14695	COG3247	response to pH
GHT02_RS14710	COG1285	pathogenesis
GHT02_RS14715	COG2197	response regulator
GHT02_RS14720	COG3065	identical protein binding
GHT02_RS14740	COG1393	Belongs to the ArsC family
GHT02_RS14745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GHT02_RS14750	COG0640	Transcriptional regulator
GHT02_RS14765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GHT02_RS14770	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GHT02_RS14775	COG0339	signal peptide processing
GHT02_RS14785	COG3104	oligopeptide transport
GHT02_RS14790	COG0589	response to stress
GHT02_RS14800	COG0306	phosphate transporter
GHT02_RS14805	COG2081	HI0933 family
GHT02_RS14850	COG2771	luxR family
GHT02_RS14850	COG2200	EAL domain
GHT02_RS14855	COG2771	luxR family
GHT02_RS14855	COG2200	EAL domain
GHT02_RS14880	COG0582	viral genome integration into host DNA
GHT02_RS14885	COG3708	Transcriptional regulator
GHT02_RS14885	COG2207	Transcriptional regulator
GHT02_RS14890	COG0582	viral genome integration into host DNA
GHT02_RS14915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS14920	COG0842	Transport permease protein
GHT02_RS14920	COG1129	ABC transporter
GHT02_RS14925	COG0842	Transport permease protein
GHT02_RS14960	COG0444	Belongs to the ABC transporter superfamily
GHT02_RS14965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GHT02_RS14970	COG0601	transmembrane transport
GHT02_RS14975	COG0747	negative chemotaxis
GHT02_RS14980	COG2091	lysine biosynthetic process via aminoadipic acid
GHT02_RS14985	COG0628	permease
GHT02_RS15000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GHT02_RS15015	COG3714	YhhN family
GHT02_RS15025	COG3776	membrane
GHT02_RS15030	COG0742	ribosomal rna small subunit methyltransferase
GHT02_RS15035	COG0552	protein localization to endoplasmic reticulum
GHT02_RS15040	COG2884	Cell division ATP-binding protein ftsE
GHT02_RS15045	COG2177	Part of the ABC transporter FtsEX involved in
GHT02_RS15050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GHT02_RS15055	COG0683	leucine binding
GHT02_RS15070	COG0456	acetyltransferase
GHT02_RS15075	COG0683	leucine binding
GHT02_RS15080	COG0559	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS15085	COG4177	L-phenylalanine transmembrane transporter activity
GHT02_RS15090	COG0411	ABC transporter
GHT02_RS15095	COG0410	ABC transporter
GHT02_RS15100	COG1653	transport
GHT02_RS15105	COG1175	transmembrane transport
GHT02_RS15110	COG0395	ABC-type sugar transport system, permease component
GHT02_RS15120	COG0584	glycerophosphoryl diester phosphodiesterase
GHT02_RS15130	COG0405	Gamma-glutamyltransferase
GHT02_RS15150	COG3157	Type VI secretion system effector, Hcp
GHT02_RS15155	COG1247	-acetyltransferase
GHT02_RS15160	COG0673	inositol 2-dehydrogenase activity
GHT02_RS15165	COG1741	Belongs to the pirin family
GHT02_RS15170	COG1609	Transcriptional regulator
GHT02_RS15175	COG3265	gluconokinase activity
GHT02_RS15180	COG2610	gluconate transmembrane transporter activity
GHT02_RS15185	COG0514	ATP-dependent DNA helicase (RecQ)
GHT02_RS15195	COG2095	MarC family integral membrane protein
GHT02_RS15200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHT02_RS15225	COG0058	SHG alpha-glucan phosphorylase activity
GHT02_RS15230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GHT02_RS15250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GHT02_RS15265	COG1349	DNA-binding transcription factor activity
GHT02_RS15270	COG4650	regulator
GHT02_RS15275	COG1690	Belongs to the RtcB family
GHT02_RS15290	COG0058	SHG alpha-glucan phosphorylase activity
GHT02_RS15295	COG1640	4-alpha-glucanotransferase
GHT02_RS15300	COG2610	gluconate transmembrane transporter activity
GHT02_RS15320	COG5464	transposase or invertase
GHT02_RS15330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GHT02_RS15335	COG1918	ferrous iron import across plasma membrane
GHT02_RS15340	COG2183	response to ionizing radiation
GHT02_RS15345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GHT02_RS15375	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GHT02_RS15385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GHT02_RS15390	COG1011	Hydrolase
GHT02_RS15400	COG0494	nUDIX hydrolase
GHT02_RS15405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GHT02_RS15410	COG4972	Pilus assembly protein
GHT02_RS15415	COG3166	PFAM Fimbrial assembly family protein
GHT02_RS15430	COG4796	Type ii and iii secretion system protein
GHT02_RS15445	COG3266	domain, Protein
GHT02_RS15450	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GHT02_RS15455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GHT02_RS15460	COG0546	phosphoglycolate phosphatase activity
GHT02_RS15465	COG0180	Tryptophanyl-tRNA synthetase
GHT02_RS15470	COG2188	Transcriptional regulator
GHT02_RS15480	COG3457	Alanine racemase
GHT02_RS15485	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GHT02_RS15490	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GHT02_RS15505	COG0626	cystathionine gamma-synthase activity
GHT02_RS15510	COG2188	Transcriptional regulator
GHT02_RS15520	COG1082	Xylose isomerase domain protein TIM barrel
GHT02_RS15525	COG2222	sugar isomerase
GHT02_RS15530	COG0531	amino acid
GHT02_RS15545	COG2116	formate transmembrane transporter activity
GHT02_RS15550	COG2146	nitrite reductase [NAD(P)H] activity
GHT02_RS15555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GHT02_RS15565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHT02_RS15575	COG2184	nucleotidyltransferase activity
GHT02_RS15580	COG0512	Glutamine amidotransferase of anthranilate synthase
GHT02_RS15585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GHT02_RS15590	COG1289	transmembrane transporter activity
GHT02_RS15595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GHT02_RS15600	COG1765	OsmC-like protein
GHT02_RS15605	COG3954	Phosphoribulokinase
GHT02_RS15615	COG0429	hydrolase of the alpha beta-hydrolase fold
GHT02_RS15620	COG0488	(ABC) transporter
GHT02_RS15635	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GHT02_RS15640	COG1047	Peptidyl-prolyl cis-trans
GHT02_RS15650	COG0545	Peptidyl-prolyl cis-trans isomerase
GHT02_RS15655	COG2964	Protein conserved in bacteria
GHT02_RS15725	COG0089	rRNA binding
GHT02_RS15815	COG0201	protein transport
GHT02_RS15855	COG0789	Transcriptional regulator
GHT02_RS15860	COG3036	rescue of stalled ribosome
GHT02_RS15870	COG0569	domain protein
GHT02_RS15890	COG0758	DNA mediated transformation
GHT02_RS15900	COG0551	DNA topoisomerase type I activity
GHT02_RS15920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GHT02_RS15960	COG1126	abc transporter atp-binding protein
GHT02_RS15965	COG0765	amino acid transport
GHT02_RS15970	COG4597	amino acid ABC transporter
GHT02_RS15975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS15985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GHT02_RS15990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS15995	COG1309	transcriptional regulator
GHT02_RS16005	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GHT02_RS16015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHT02_RS16025	COG4145	pantothenate transmembrane transporter activity
GHT02_RS16030	COG3924	membrane
GHT02_RS16035	COG0439	Biotin carboxylase
GHT02_RS16040	COG0511	ligase activity, forming carbon-carbon bonds
GHT02_RS16045	COG0604	alcohol dehydrogenase
GHT02_RS16050	COG2200	EAL domain
GHT02_RS16050	COG2199	diguanylate cyclase activity
GHT02_RS16055	COG1077	Cell shape determining protein MreB Mrl
GHT02_RS16060	COG1792	Involved in formation and maintenance of cell shape
GHT02_RS16065	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GHT02_RS16075	COG1530	ribonuclease E activity
GHT02_RS16080	COG3164	Protein of unknown function
GHT02_RS16085	COG0312	modulator of DNA gyrase
GHT02_RS16090	COG0583	DNA-binding transcription factor activity
GHT02_RS16110	COG2732	(Barnase) inhibitor
GHT02_RS16130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GHT02_RS16135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GHT02_RS16140	COG3105	Protein conserved in bacteria
GHT02_RS16145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GHT02_RS16160	COG0625	glutathione transferase activity
GHT02_RS16165	COG2969	positive regulation of protein catabolic process
GHT02_RS16170	COG3069	C4-dicarboxylate transmembrane transporter activity
GHT02_RS16200	COG2731	YhcH YjgK YiaL family protein
GHT02_RS16205	COG4804	nuclease activity
GHT02_RS16210	COG0493	'glutamate synthase
GHT02_RS16215	COG0069	glutamate synthase activity
GHT02_RS16215	COG0070	glutamate synthase
GHT02_RS16215	COG0067	glutamate synthase
GHT02_RS16220	COG1242	4 iron, 4 sulfur cluster binding
GHT02_RS16225	COG2198	Histidine kinase
GHT02_RS16225	COG5002	protein histidine kinase activity
GHT02_RS16225	COG0784	Response regulator, receiver
GHT02_RS16230	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GHT02_RS16240	COG0515	serine threonine protein kinase
GHT02_RS16245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS16260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GHT02_RS16265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GHT02_RS16270	COG1137	ATPase activity
GHT02_RS16275	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GHT02_RS16280	COG3117	lipopolysaccharide transmembrane transporter activity
GHT02_RS16285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GHT02_RS16290	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GHT02_RS16290	COG0517	IMP dehydrogenase activity
GHT02_RS16295	COG0530	calcium, potassium:sodium antiporter activity
GHT02_RS16300	COG1127	ABC transporter
GHT02_RS16305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GHT02_RS16310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GHT02_RS16315	COG2854	intermembrane phospholipid transfer
GHT02_RS16320	COG3113	response to antibiotic
GHT02_RS16325	COG5007	Belongs to the BolA IbaG family
GHT02_RS16335	COG3423	Transcriptional regulator
GHT02_RS16340	COG0142	geranyltranstransferase activity
GHT02_RS16355	COG0697	spore germination
GHT02_RS16365	COG2027	D-alanyl-D-alanine carboxypeptidase
GHT02_RS16370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GHT02_RS16375	COG1534	Rna-binding protein
GHT02_RS16385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GHT02_RS16390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GHT02_RS16400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GHT02_RS16410	COG2194	sulfuric ester hydrolase activity
GHT02_RS16430	COG0195	Participates in both transcription termination and antitermination
GHT02_RS16470	COG0513	Belongs to the DEAD box helicase family
GHT02_RS16475	COG0814	amino acid
GHT02_RS16480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GHT02_RS16485	COG0826	peptidase U32
GHT02_RS16490	COG0826	peptidase U32
GHT02_RS16495	COG3154	lipid carrier protein
GHT02_RS16500	COG3153	acetyltransferase
GHT02_RS16515	COG0693	protein deglycase activity
GHT02_RS16520	COG0702	epimerase
GHT02_RS16525	COG0701	Predicted permease
GHT02_RS16530	COG2823	Periplasmic or secreted lipoprotein
GHT02_RS16550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GHT02_RS16555	COG3539	Fimbrial protein
GHT02_RS16560	COG3188	usher protein
GHT02_RS16565	COG3121	Chaperone
GHT02_RS16570	COG3539	Fimbrial protein
GHT02_RS16575	COG0363	glucosamine-6-phosphate deaminase activity
GHT02_RS16580	COG3716	PTS system mannose fructose sorbose family IID component
GHT02_RS16585	COG3715	PTS system
GHT02_RS16590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS16600	COG2222	sugar isomerase
GHT02_RS16605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GHT02_RS16610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS16615	COG3716	PTS system mannose fructose sorbose family IID component
GHT02_RS16625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS16635	COG1349	DNA-binding transcription factor activity
GHT02_RS16645	COG2002	toxin-antitoxin pair type II binding
GHT02_RS16650	COG2721	sulfolactate sulfo-lyase activity
GHT02_RS16655	COG2271	Major facilitator Superfamily
GHT02_RS16665	COG2084	Dehydrogenase
GHT02_RS16670	COG1929	Belongs to the glycerate kinase type-1 family
GHT02_RS16695	COG0583	DNA-binding transcription factor activity
GHT02_RS16700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GHT02_RS16710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHT02_RS16715	COG1882	Formate acetyltransferase
GHT02_RS16720	COG0251	oxidation-reduction process
GHT02_RS16725	COG1760	l-serine dehydratase
GHT02_RS16730	COG0814	amino acid
GHT02_RS16745	COG1741	Belongs to the pirin family
GHT02_RS16750	COG0583	DNA-binding transcription factor activity
GHT02_RS16755	COG3152	Membrane
GHT02_RS16760	COG3152	Membrane
GHT02_RS16765	COG0435	Glutathione S-transferase
GHT02_RS16770	COG2259	Doxx family
GHT02_RS16780	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GHT02_RS16785	COG4575	ribosome binding
GHT02_RS16790	COG1422	Protein of unknown function (DUF1090)
GHT02_RS16800	COG0586	Pfam SNARE associated Golgi protein
GHT02_RS16805	COG2186	Transcriptional regulator
GHT02_RS16830	COG2271	Major facilitator Superfamily
GHT02_RS16840	COG2721	sulfolactate sulfo-lyase activity
GHT02_RS16850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GHT02_RS16855	COG0861	Integral membrane protein TerC family
GHT02_RS16860	COG0673	inositol 2-dehydrogenase activity
GHT02_RS16865	COG2949	membrane
GHT02_RS16870	COG1451	nucleotide metabolic process
GHT02_RS16885	COG5499	transcription regulator containing HTH domain
GHT02_RS16890	COG0446	pyridine nucleotide-disulphide oxidoreductase
GHT02_RS16890	COG1902	pentaerythritol trinitrate reductase activity
GHT02_RS16895	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GHT02_RS16895	COG3408	Glycogen debranching enzyme
GHT02_RS16905	COG0531	amino acid
GHT02_RS16910	COG2731	YhcH YjgK YiaL family protein
GHT02_RS16915	COG3250	beta-galactosidase activity
GHT02_RS16920	COG1609	Transcriptional regulator
GHT02_RS16925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GHT02_RS16935	COG0840	transmembrane signaling receptor activity
GHT02_RS16940	COG1695	Transcriptional regulator
GHT02_RS16945	COG2375	cellular response to nickel ion
GHT02_RS16960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GHT02_RS16965	COG0358	DNA primase activity
GHT02_RS16970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GHT02_RS16995	COG3423	Transcriptional regulator
GHT02_RS17005	COG2842	Transposition protein
GHT02_RS17035	COG4396	Host-nuclease inhibitor protein Gam
GHT02_RS17085	COG5566	PFAM Mor transcription activator
GHT02_RS17125	COG4373	Mu-like prophage FluMu protein gp28
GHT02_RS17130	COG4383	Mu-like prophage protein gp29
GHT02_RS17135	COG2369	cell adhesion
GHT02_RS17145	COG5005	Phage virion morphogenesis
GHT02_RS17150	COG4388	Caudovirus prohead serine protease
GHT02_RS17155	COG4397	Mu-like prophage major head subunit gpT
GHT02_RS17180	COG4386	tail sheath protein
GHT02_RS17190	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
GHT02_RS17210	COG4384	Bacteriophage Mu Gp45 protein
GHT02_RS17220	COG3299	homolog of phage Mu protein gp47
GHT02_RS17240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GHT02_RS17270	COG0270	DNA (cytosine-5-)-methyltransferase activity
GHT02_RS17280	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GHT02_RS17285	COG0583	DNA-binding transcription factor activity
GHT02_RS17295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GHT02_RS17310	COG4991	sh3 domain protein
GHT02_RS17315	COG3025	triphosphatase activity
GHT02_RS17340	COG2268	Band 7 protein
GHT02_RS17345	COG1585	Membrane protein implicated in regulation of membrane protease activity
GHT02_RS17355	COG3539	Fimbrial protein
GHT02_RS17360	COG3121	Chaperone
GHT02_RS17365	COG3188	usher protein
GHT02_RS17370	COG3539	Fimbrial protein
GHT02_RS17375	COG2960	long-chain fatty acid transporting porin activity
GHT02_RS17395	COG3384	dioxygenase
GHT02_RS17400	COG0754	glutathionylspermidine amidase activity
GHT02_RS17410	COG1538	Outer membrane efflux protein
GHT02_RS17415	COG0494	nUDIX hydrolase
GHT02_RS17420	COG3151	Protein conserved in bacteria
GHT02_RS17425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GHT02_RS17430	COG3150	esterase
GHT02_RS17435	COG0187	DNA topoisomerase II activity
GHT02_RS17440	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GHT02_RS17445	COG2249	NAD(P)H dehydrogenase (quinone) activity
GHT02_RS17455	COG0642	Histidine kinase
GHT02_RS17460	COG0745	RESPONSE REGULATOR receiver
GHT02_RS17465	COG3111	PFAM Bacterial OB fold (BOF) protein
GHT02_RS17470	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GHT02_RS17475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHT02_RS17480	COG0204	Acyl-transferase
GHT02_RS17485	COG2132	Multicopper oxidase
GHT02_RS17490	COG1032	radical SAM domain protein
GHT02_RS17495	COG4238	major outer membrane lipoprotein
GHT02_RS17505	COG0656	L-ascorbic acid biosynthetic process
GHT02_RS17510	COG1979	alcohol dehydrogenase
GHT02_RS17515	COG2207	Transcriptional regulator
GHT02_RS17520	COG0586	Pfam SNARE associated Golgi protein
GHT02_RS17525	COG0626	cystathionine gamma-synthase activity
GHT02_RS17530	COG0811	peptide transport
GHT02_RS17535	COG0848	biopolymer transport protein
GHT02_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS17550	COG0667	Aldo Keto reductase
GHT02_RS17565	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GHT02_RS17570	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS17575	COG5557	Pfam Polysulphide reductase, NrfD
GHT02_RS17580	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GHT02_RS17585	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GHT02_RS17590	COG1773	rubredoxin
GHT02_RS17600	COG0298	carbon dioxide binding
GHT02_RS17605	COG0625	glutathione transferase activity
GHT02_RS17610	COG0754	glutathionylspermidine amidase activity
GHT02_RS17615	COG0306	phosphate transporter
GHT02_RS17620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHT02_RS17625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHT02_RS17630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHT02_RS17635	COG2244	polysaccharide biosynthetic process
GHT02_RS17645	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GHT02_RS17650	COG0795	lipopolysaccharide-transporting ATPase activity
GHT02_RS17660	COG0156	8-amino-7-oxononanoate synthase activity
GHT02_RS17665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHT02_RS17675	COG0318	PFAM AMP-dependent synthetase and ligase
GHT02_RS17680	COG0456	acetyltransferase
GHT02_RS17685	COG2186	Transcriptional regulator
GHT02_RS17690	COG0277	FAD linked oxidase domain protein
GHT02_RS17695	COG0277	FAD linked oxidase domain protein
GHT02_RS17700	COG0247	lactate metabolic process
GHT02_RS17705	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GHT02_RS17715	COG1620	l-lactate permease
GHT02_RS17745	COG1811	Na channel or pump
GHT02_RS17750	COG1982	Orn Lys Arg decarboxylase major
GHT02_RS17755	COG2211	Major facilitator Superfamily
GHT02_RS17770	COG1194	a g-specific adenine glycosylase
GHT02_RS17780	COG3171	Protein conserved in bacteria
GHT02_RS17790	COG0252	asparaginase activity
GHT02_RS17800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GHT02_RS17815	COG0762	integral membrane protein
GHT02_RS17820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GHT02_RS17825	COG2805	Type II/IV secretion system protein
GHT02_RS17840	COG0189	ligase activity
GHT02_RS17845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GHT02_RS17850	COG2356	endonuclease I
GHT02_RS17860	COG2814	Major facilitator Superfamily
GHT02_RS17880	COG1166	arginine decarboxylase activity
GHT02_RS17895	COG0501	Belongs to the peptidase M48B family
GHT02_RS17900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GHT02_RS17905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS17910	COG2213	PTS system mannitol-specific
GHT02_RS17915	COG1063	alcohol dehydrogenase
GHT02_RS17920	COG1494	fructose-1,6-bisphosphatase
GHT02_RS17930	COG1072	(Pantothenic acid kinase))
GHT02_RS17935	COG1122	ATPase activity
GHT02_RS17940	COG1122	ATPase activity
GHT02_RS17970	COG0191	fructose-bisphosphate aldolase activity
GHT02_RS17975	COG0668	transmembrane transport
GHT02_RS17985	COG2968	Membrane
GHT02_RS17990	COG0583	DNA-binding transcription factor activity
GHT02_RS17995	COG0427	acetyl-CoA hydrolase
GHT02_RS18000	COG1024	Enoyl-CoA hydratase
GHT02_RS18005	COG1703	isobutyryl-CoA mutase activity
GHT02_RS18010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GHT02_RS18010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GHT02_RS18030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GHT02_RS18045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GHT02_RS18065	COG0006	proline dipeptidase activity
GHT02_RS18070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GHT02_RS18075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GHT02_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS18105	COG2723	6-phospho-beta-galactosidase activity
GHT02_RS18115	COG1272	protein, Hemolysin III
GHT02_RS18120	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS18130	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GHT02_RS18140	COG0716	FMN binding
GHT02_RS18145	COG4974	Belongs to the 'phage' integrase family
GHT02_RS18150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GHT02_RS18155	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GHT02_RS18185	COG2233	PERMEase
GHT02_RS18190	COG0493	'glutamate synthase
GHT02_RS18190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS18195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS18200	COG2252	PERMEase
GHT02_RS18205	COG0402	S-adenosylhomocysteine deaminase activity
GHT02_RS18210	COG2233	PERMEase
GHT02_RS18215	COG2080	2 iron, 2 sulfur cluster binding
GHT02_RS18215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GHT02_RS18220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GHT02_RS18225	COG0402	S-adenosylhomocysteine deaminase activity
GHT02_RS18230	COG0493	'glutamate synthase
GHT02_RS18230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS18235	COG2068	MobA-Related Protein
GHT02_RS18240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHT02_RS18245	COG3608	succinylglutamate desuccinylase aspartoacylase
GHT02_RS18245	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GHT02_RS18250	COG0549	Belongs to the carbamate kinase family
GHT02_RS18260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GHT02_RS18265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GHT02_RS18270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GHT02_RS18275	COG3829	transcription factor binding
GHT02_RS18280	COG2080	2 iron, 2 sulfur cluster binding
GHT02_RS18285	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GHT02_RS18290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GHT02_RS18295	COG4942	peptidase
GHT02_RS18305	COG0582	viral genome integration into host DNA
GHT02_RS18505	COG0741	lytic transglycosylase activity
GHT02_RS18515	COG3710	Transcriptional regulator
GHT02_RS18515	COG0457	Tetratricopeptide repeat
GHT02_RS18520	COG0457	Tetratricopeptide repeat
GHT02_RS18545	COG3710	Transcriptional regulator
GHT02_RS18550	COG2771	luxR family
GHT02_RS18555	COG0814	amino acid
GHT02_RS18560	COG0183	Belongs to the thiolase family
GHT02_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS18575	COG2814	Major facilitator Superfamily
GHT02_RS18580	COG1794	racemase activity, acting on amino acids and derivatives
GHT02_RS18585	COG0583	DNA-binding transcription factor activity
GHT02_RS18595	COG1609	Transcriptional regulator
GHT02_RS18610	COG0667	Aldo Keto reductase
GHT02_RS18620	COG0861	Integral membrane protein TerC family
GHT02_RS18635	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GHT02_RS18650	COG2165	general secretion pathway protein
GHT02_RS18655	COG4795	General secretion pathway protein
GHT02_RS18665	COG4967	type IV pilus modification protein PilV
GHT02_RS18670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GHT02_RS18675	COG1025	Belongs to the peptidase M16 family
GHT02_RS18680	COG1074	ATP-dependent DNA helicase activity
GHT02_RS18685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GHT02_RS18690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GHT02_RS18690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GHT02_RS18695	COG0860	N-Acetylmuramoyl-L-alanine amidase
GHT02_RS18700	COG3711	transcriptional antiterminator
GHT02_RS18705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS18705	COG1263	PTS System
GHT02_RS18710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GHT02_RS18740	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GHT02_RS18745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GHT02_RS18750	COG2166	iron-sulfur cluster assembly
GHT02_RS18755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GHT02_RS18765	COG0583	DNA-binding transcription factor activity
GHT02_RS18770	COG2363	Small membrane protein
GHT02_RS18780	COG1349	DNA-binding transcription factor activity
GHT02_RS18790	COG1070	Carbohydrate kinase
GHT02_RS18800	COG0738	Major facilitator superfamily
GHT02_RS18805	COG0235	Class ii aldolase
GHT02_RS18810	COG1454	alcohol dehydrogenase
GHT02_RS18820	COG1760	l-serine dehydratase
GHT02_RS18825	COG0814	amino acid
GHT02_RS18830	COG1611	Belongs to the LOG family
GHT02_RS18845	COG3098	single-species biofilm formation
GHT02_RS18850	COG0564	pseudouridine synthase activity
GHT02_RS18855	COG0716	FMN binding
GHT02_RS18860	COG2271	Major facilitator Superfamily
GHT02_RS18865	COG4948	Mandelate Racemase Muconate Lactonizing
GHT02_RS18870	COG4948	Mandelate Racemase Muconate Lactonizing
GHT02_RS18875	COG3850	Histidine kinase
GHT02_RS18875	COG2205	protein histidine kinase activity
GHT02_RS18875	COG3437	response regulator, receiver
GHT02_RS18875	COG4999	Histidine kinase
GHT02_RS18885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GHT02_RS18890	COG2336	PFAM SpoVT AbrB
GHT02_RS18895	COG2337	Toxic component of a toxin-antitoxin (TA) module
GHT02_RS18900	COG3956	TIGRFAM MazG family protein
GHT02_RS18915	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GHT02_RS18925	COG0602	queuosine metabolic process
GHT02_RS18930	COG1070	Carbohydrate kinase
GHT02_RS18935	COG2223	nitrite transmembrane transporter activity
GHT02_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS18945	COG0277	FAD linked oxidase domain protein
GHT02_RS18950	COG0477	Major facilitator Superfamily
GHT02_RS18955	COG2086	electron transfer activity
GHT02_RS18960	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GHT02_RS18965	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GHT02_RS18970	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GHT02_RS18975	COG0644	oxidoreductase
GHT02_RS18980	COG0720	synthase
GHT02_RS19005	COG1203	CRISPR-associated helicase, Cas3
GHT02_RS19020	COG1857	crispr-associated protein
GHT02_RS19035	COG1518	maintenance of DNA repeat elements
GHT02_RS19040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHT02_RS19045	COG2234	aminopeptidase activity
GHT02_RS19105	COG1388	LysM domain
GHT02_RS19105	COG4942	peptidase
GHT02_RS19125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GHT02_RS19135	COG2610	gluconate transmembrane transporter activity
GHT02_RS19140	COG3622	Belongs to the hyi family
GHT02_RS19145	COG0235	Class ii aldolase
GHT02_RS19150	COG3395	kinase activity
GHT02_RS19155	COG2084	Dehydrogenase
GHT02_RS19160	COG1349	DNA-binding transcription factor activity
GHT02_RS19165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GHT02_RS19185	COG3604	Transcriptional regulator
GHT02_RS19190	COG0309	Hydrogenase expression formation protein (HypE)
GHT02_RS19195	COG0409	Hydrogenase expression formation protein
GHT02_RS19200	COG0298	carbon dioxide binding
GHT02_RS19205	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GHT02_RS19210	COG0375	protein maturation
GHT02_RS19220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS19225	COG0651	ATP synthesis coupled electron transport
GHT02_RS19230	COG0650	Formate hydrogenlyase subunit 4
GHT02_RS19235	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GHT02_RS19235	COG3261	NADH dehydrogenase
GHT02_RS19240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GHT02_RS19245	COG3260	NADH ubiquinone oxidoreductase 20
GHT02_RS19255	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GHT02_RS19265	COG5499	transcription regulator containing HTH domain
GHT02_RS19270	COG2723	6-phospho-beta-galactosidase activity
GHT02_RS19275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS19275	COG1263	PTS System
GHT02_RS19280	COG1609	Transcriptional regulator
GHT02_RS19285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS19290	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GHT02_RS19315	COG1349	DNA-binding transcription factor activity
GHT02_RS19320	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS19325	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS19335	COG3732	PTS system glucitol sorbitol-specific
GHT02_RS19340	COG3730	PTS system glucitol sorbitol-specific
GHT02_RS19345	COG2951	lytic endotransglycosylase activity
GHT02_RS19350	COG1546	Belongs to the CinA family
GHT02_RS19370	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GHT02_RS19400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GHT02_RS19405	COG1238	metal cluster binding
GHT02_RS19420	COG2814	Major facilitator Superfamily
GHT02_RS19425	COG1566	PFAM secretion protein HlyD family protein
GHT02_RS19430	COG1846	Transcriptional regulator
GHT02_RS19440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GHT02_RS19445	COG2814	Major facilitator Superfamily
GHT02_RS19450	COG2113	Glycine betaine
GHT02_RS19455	COG4176	ABC-type proline glycine betaine transport system permease component
GHT02_RS19460	COG4175	Glycine betaine
GHT02_RS19465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHT02_RS19470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHT02_RS19480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GHT02_RS19485	COG4575	ribosome binding
GHT02_RS19500	COG2916	Histone family protein nucleoid-structuring protein H-NS
GHT02_RS19505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHT02_RS19510	COG0640	Transcriptional regulator
GHT02_RS19515	COG0401	homolog of Blt101
GHT02_RS19520	COG1652	LysM domain
GHT02_RS19525	COG1802	Transcriptional regulator
GHT02_RS19530	COG1113	amino acid transport
GHT02_RS19535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GHT02_RS19540	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS19545	COG0579	oxidoreductase
GHT02_RS19580	COG0582	viral genome integration into host DNA
GHT02_RS19585	COG0582	viral genome integration into host DNA
GHT02_RS19620	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GHT02_RS19625	COG5532	Uncharacterized conserved protein (DUF2303)
GHT02_RS19640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GHT02_RS19645	COG4197	protein conserved in bacteria, prophage-related
GHT02_RS19665	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
GHT02_RS19680	COG1846	Transcriptional regulator
GHT02_RS19690	COG4725	Belongs to the MT-A70-like family
GHT02_RS19700	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GHT02_RS19710	COG1403	HNH endonuclease
GHT02_RS19715	COG0484	heat shock protein binding
GHT02_RS19765	COG3772	lysozyme
GHT02_RS19815	COG0740	serine-type endopeptidase activity
GHT02_RS19890	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS19890	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS19925	COG2867	negative regulation of translational initiation
GHT02_RS19935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GHT02_RS19940	COG0497	DNA recombination
GHT02_RS19955	COG4536	flavin adenine dinucleotide binding
GHT02_RS19960	COG4137	Cytochrome C assembly protein
GHT02_RS19965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHT02_RS19990	COG2885	chlorophyll binding
GHT02_RS19995	COG2199	diguanylate cyclase activity
GHT02_RS20010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHT02_RS20015	COG0287	Prephenate dehydrogenase
GHT02_RS20015	COG1605	Chorismate mutase
GHT02_RS20020	COG1605	Chorismate mutase
GHT02_RS20020	COG0077	Prephenate dehydratase
GHT02_RS20030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GHT02_RS20035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GHT02_RS20040	COG0564	pseudouridine synthase activity
GHT02_RS20045	COG1496	oxidoreductase activity
GHT02_RS20050	COG0542	response to heat
GHT02_RS20075	COG0477	Major facilitator Superfamily
GHT02_RS20080	COG5544	Lipoprotein
GHT02_RS20085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHT02_RS20090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GHT02_RS20090	COG0045	succinate-CoA ligase (ADP-forming) activity
GHT02_RS20090	COG1042	CoA-binding domain protein
GHT02_RS20095	COG3148	PFAM DTW domain containing protein
GHT02_RS20100	COG3118	belongs to the thioredoxin family
GHT02_RS20105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHT02_RS20125	COG0583	DNA-binding transcription factor activity
GHT02_RS20130	COG0513	Belongs to the DEAD box helicase family
GHT02_RS20140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GHT02_RS20150	COG1595	DNA-templated transcription, initiation
GHT02_RS20155	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GHT02_RS20160	COG3026	antisigma factor binding
GHT02_RS20165	COG3086	response to oxidative stress
GHT02_RS20175	COG0681	Belongs to the peptidase S26 family
GHT02_RS20195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GHT02_RS20210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS20215	COG1737	Transcriptional regulator
GHT02_RS20220	COG0560	Phosphoserine phosphatase
GHT02_RS20235	COG0047	phosphoribosylformylglycinamidine synthase activity
GHT02_RS20235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHT02_RS20240	COG2205	protein histidine kinase activity
GHT02_RS20245	COG3170	Tfp pilus assembly protein FimV
GHT02_RS20250	COG2204	response regulator
GHT02_RS20255	COG0347	Belongs to the P(II) protein family
GHT02_RS20260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GHT02_RS20260	COG1017	nitric oxide dioxygenase activity
GHT02_RS20270	COG1940	carbohydrate kinase activity
GHT02_RS20275	COG0457	Tetratricopeptide repeat
GHT02_RS20280	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS20285	COG1129	ABC transporter
GHT02_RS20290	COG1172	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS20295	COG1063	alcohol dehydrogenase
GHT02_RS20300	COG2017	converts alpha-aldose to the beta-anomer
GHT02_RS20305	COG2259	Doxx family
GHT02_RS20330	COG4638	Rieske (2fe-2S)
GHT02_RS20335	COG0583	DNA-binding transcription factor activity
GHT02_RS20340	COG2814	Major facilitator Superfamily
GHT02_RS20345	COG3711	transcriptional antiterminator
GHT02_RS20350	COG1073	alpha beta
GHT02_RS20355	COG0483	inositol monophosphate 1-phosphatase activity
GHT02_RS20375	COG0822	iron-sulfur transferase activity
GHT02_RS20395	COG0633	Ferredoxin
GHT02_RS20400	COG2975	iron-sulfur cluster assembly
GHT02_RS20415	COG2897	thiosulfate sulfurtransferase activity
GHT02_RS20420	COG2373	Large extracellular alpha-helical protein
GHT02_RS20425	COG4953	penicillin-binding protein 1C
GHT02_RS20455	COG2976	Protein conserved in bacteria
GHT02_RS20470	COG1645	bacterial-type flagellum-dependent swarming motility
GHT02_RS20480	COG0517	IMP dehydrogenase activity
GHT02_RS20480	COG0516	GMP reductase activity
GHT02_RS20495	COG3133	Outer membrane lipoprotein
GHT02_RS20510	COG2200	EAL domain
GHT02_RS20515	COG0248	Ppx GppA phosphatase
GHT02_RS20520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GHT02_RS20525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GHT02_RS20540	COG2233	PERMEase
GHT02_RS20550	COG1393	Belongs to the ArsC family
GHT02_RS20555	COG4783	chaperone-mediated protein folding
GHT02_RS20560	COG0628	permease
GHT02_RS20565	COG2116	formate transmembrane transporter activity
GHT02_RS20570	COG3604	Transcriptional regulator
GHT02_RS20580	COG3260	NADH ubiquinone oxidoreductase 20
GHT02_RS20585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GHT02_RS20590	COG3261	NADH dehydrogenase
GHT02_RS20590	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GHT02_RS20595	COG0651	ATP synthesis coupled electron transport
GHT02_RS20600	COG4237	Hydrogenase 4 membrane
GHT02_RS20610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GHT02_RS20615	COG0650	Formate hydrogenlyase subunit 4
GHT02_RS20620	COG0651	ATP synthesis coupled electron transport
GHT02_RS20625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS20630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GHT02_RS20635	COG2716	regulation of RNA biosynthetic process
GHT02_RS20645	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GHT02_RS20665	COG2321	neutral zinc metallopeptidase
GHT02_RS20675	COG0400	carboxylic ester hydrolase activity
GHT02_RS20690	COG1393	Belongs to the ArsC family
GHT02_RS20700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GHT02_RS20705	COG3850	Histidine kinase
GHT02_RS20710	COG0493	'glutamate synthase
GHT02_RS20710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS20720	COG5342	invasion associated locus B
GHT02_RS20725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GHT02_RS20730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GHT02_RS20735	COG0281	malic enzyme
GHT02_RS20735	COG0280	phosphate acetyltransferase
GHT02_RS20740	COG4810	utilization protein
GHT02_RS20745	COG4917	ethanolamine utilization protein
GHT02_RS20750	COG4766	ethanolamine catabolic process
GHT02_RS20755	COG4812	Cobalamin adenosyltransferase
GHT02_RS20760	COG0280	phosphate acetyltransferase
GHT02_RS20765	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GHT02_RS20770	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GHT02_RS20775	COG1012	belongs to the aldehyde dehydrogenase family
GHT02_RS20780	COG4820	ethanolamine utilization protein (EutJ)
GHT02_RS20785	COG1454	alcohol dehydrogenase
GHT02_RS20790	COG3192	ethanolamine utilization protein
GHT02_RS20795	COG4819	ethanolamine utilization protein
GHT02_RS20800	COG4303	Ethanolamine ammonia lyase large subunit
GHT02_RS20810	COG4816	utilization protein
GHT02_RS20815	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GHT02_RS20820	COG2207	Transcriptional regulator
GHT02_RS20830	COG0860	N-Acetylmuramoyl-L-alanine amidase
GHT02_RS20850	COG2837	iron assimilation
GHT02_RS20855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GHT02_RS20860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS20860	COG1263	PTS System
GHT02_RS20875	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS20880	COG4150	thiosulfate binding
GHT02_RS20885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GHT02_RS20890	COG4208	sulfate ABC transporter
GHT02_RS20895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GHT02_RS20900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GHT02_RS20915	COG2190	(PTS) system
GHT02_RS20920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHT02_RS20925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS20930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GHT02_RS20950	COG3530	Putative quorum-sensing-regulated virulence factor
GHT02_RS20955	COG0385	Bile acid
GHT02_RS20960	COG0583	DNA-binding transcription factor activity
GHT02_RS20970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GHT02_RS20975	COG2211	Major facilitator Superfamily
GHT02_RS20985	COG0583	DNA-binding transcription factor activity
GHT02_RS21020	COG3415	Transposase
GHT02_RS21025	COG3415	Transposase
GHT02_RS21040	COG2199	diguanylate cyclase activity
GHT02_RS21040	COG2200	EAL domain
GHT02_RS21045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GHT02_RS21070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS21075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS21080	COG0006	proline dipeptidase activity
GHT02_RS21085	COG1363	Peptidase, m42
GHT02_RS21095	COG2207	Transcriptional regulator
GHT02_RS21100	COG3279	Response regulator of the LytR AlgR family
GHT02_RS21105	COG3275	phosphorelay sensor kinase activity
GHT02_RS21110	COG0436	Aminotransferase
GHT02_RS21120	COG1560	Kdo2-lipid A biosynthetic process
GHT02_RS21145	COG0028	Belongs to the TPP enzyme family
GHT02_RS21150	COG0679	Auxin Efflux Carrier
GHT02_RS21155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GHT02_RS21160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS21160	COG2198	Histidine kinase
GHT02_RS21160	COG2205	protein histidine kinase activity
GHT02_RS21160	COG0784	Response regulator, receiver
GHT02_RS21165	COG2197	response regulator
GHT02_RS21170	COG1566	PFAM secretion protein HlyD family protein
GHT02_RS21175	COG0477	Major facilitator Superfamily
GHT02_RS21215	COG2116	formate transmembrane transporter activity
GHT02_RS21220	COG2853	Lipoprotein
GHT02_RS21230	COG2067	long-chain fatty acid transport protein
GHT02_RS21235	COG3691	Protein conserved in bacteria
GHT02_RS21250	COG2062	phosphohistidine phosphatase, SixA
GHT02_RS21255	COG3539	Fimbrial protein
GHT02_RS21260	COG3188	usher protein
GHT02_RS21265	COG3121	Chaperone
GHT02_RS21270	COG3539	Fimbrial protein
GHT02_RS21275	COG3539	Fimbrial protein
GHT02_RS21280	COG3539	Fimbrial protein
GHT02_RS21310	COG0730	response to heat
GHT02_RS21315	COG3101	peptidyl-lysine hydroxylation
GHT02_RS21325	COG3547	Transposase (IS116 IS110 IS902 family)
GHT02_RS21335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GHT02_RS21340	COG2814	Major facilitator Superfamily
GHT02_RS21355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHT02_RS21365	COG0586	Pfam SNARE associated Golgi protein
GHT02_RS21375	COG0285	dihydrofolate synthase activity
GHT02_RS21380	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GHT02_RS21385	COG1286	toxin biosynthetic process
GHT02_RS21390	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GHT02_RS21395	COG0163	prenyltransferase activity
GHT02_RS21400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS21405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS21410	COG4215	(ABC) transporter
GHT02_RS21415	COG4160	amino acid transport
GHT02_RS21420	COG4598	ABC transporter
GHT02_RS21425	COG5464	transposase or invertase
GHT02_RS21430	COG1090	epimerase
GHT02_RS21435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GHT02_RS21440	COG0625	glutathione transferase activity
GHT02_RS21445	COG0625	glutathione transferase activity
GHT02_RS21450	COG0622	Phosphoesterase
GHT02_RS21455	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GHT02_RS21460	COG1288	antiporter activity
GHT02_RS21465	COG0280	phosphate acetyltransferase
GHT02_RS21465	COG0857	belongs to the CobB CobQ family
GHT02_RS21470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHT02_RS21485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GHT02_RS21490	COG0471	metal ion transport
GHT02_RS21490	COG0490	domain, Protein
GHT02_RS21500	COG0436	Aminotransferase
GHT02_RS21505	COG0583	DNA-binding transcription factor activity
GHT02_RS21525	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GHT02_RS21530	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GHT02_RS21535	COG1034	ATP synthesis coupled electron transport
GHT02_RS21550	COG0839	Belongs to the complex I subunit 6 family
GHT02_RS21560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GHT02_RS21565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GHT02_RS21595	COG2153	protein acetylation
GHT02_RS21600	COG4575	ribosome binding
GHT02_RS21605	COG1169	isochorismate synthase
GHT02_RS21620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GHT02_RS21630	COG0318	PFAM AMP-dependent synthetase and ligase
GHT02_RS21700	COG5464	transposase or invertase
GHT02_RS21705	COG0247	lactate metabolic process
GHT02_RS21715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GHT02_RS21720	COG2271	Major facilitator Superfamily
GHT02_RS21725	COG0584	glycerophosphoryl diester phosphodiesterase
GHT02_RS21735	COG3642	lipopolysaccharide core region biosynthetic process
GHT02_RS21740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GHT02_RS21745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHT02_RS21750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHT02_RS21755	COG3468	outer membrane autotransporter barrel domain protein
GHT02_RS21765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHT02_RS21770	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
GHT02_RS21775	COG3234	Protein of unknown function (DUF1175)
GHT02_RS21780	COG2373	Large extracellular alpha-helical protein
GHT02_RS21785	COG5445	Predicted secreted protein (DUF2300)
GHT02_RS21790	COG4676	Protein conserved in bacteria
GHT02_RS21795	COG2205	protein histidine kinase activity
GHT02_RS21795	COG0784	Response regulator, receiver
GHT02_RS21800	COG2197	response regulator
GHT02_RS21805	COG2198	Histidine kinase
GHT02_RS21805	COG0642	Histidine kinase
GHT02_RS21810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GHT02_RS21815	COG1477	protein flavinylation
GHT02_RS21820	COG2169	Transcriptional regulator
GHT02_RS21820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GHT02_RS21825	COG3145	DNA-N1-methyladenine dioxygenase activity
GHT02_RS21830	COG4615	Cyclic peptide transporter
GHT02_RS21850	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS21850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GHT02_RS21855	COG3062	negative regulation of establishment of protein localization
GHT02_RS21865	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS21870	COG0348	domain, Protein
GHT02_RS21875	COG3043	anaerobic respiration
GHT02_RS21880	COG3005	denitrification pathway
GHT02_RS21885	COG4133	protoheme IX ABC transporter activity
GHT02_RS21890	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GHT02_RS21895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GHT02_RS21900	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GHT02_RS21910	COG1138	Cytochrome C-type biogenesis protein
GHT02_RS21915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GHT02_RS21920	COG4235	cytochrome complex assembly
GHT02_RS21920	COG3088	subunit of a heme lyase
GHT02_RS21925	COG2197	response regulator
GHT02_RS21940	COG3083	sulfuric ester hydrolase activity
GHT02_RS21960	COG1061	Type III restriction enzyme res subunit
GHT02_RS21965	COG1187	pseudouridine synthase activity
GHT02_RS21970	COG2814	Major facilitator Superfamily
GHT02_RS21980	COG4172	Belongs to the ABC transporter superfamily
GHT02_RS21985	COG4239	(ABC) transporter, permease
GHT02_RS21990	COG4174	ABC transporter (Permease)
GHT02_RS21995	COG4166	transmembrane transport
GHT02_RS22000	COG2200	EAL domain
GHT02_RS22005	COG0791	NLP P60 protein
GHT02_RS22010	COG0671	phosphoesterase, PA-phosphatase related
GHT02_RS22015	COG0523	cobalamin synthesis protein
GHT02_RS22020	COG0246	Mannitol dehydrogenase
GHT02_RS22035	COG2814	Major facilitator Superfamily
GHT02_RS22040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS22040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS22045	COG1105	Belongs to the carbohydrate kinase PfkB family
GHT02_RS22050	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GHT02_RS22050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS22050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GHT02_RS22055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHT02_RS22060	COG2313	pseudouridylate synthase activity
GHT02_RS22065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GHT02_RS22070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GHT02_RS22080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GHT02_RS22085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHT02_RS22085	COG1522	sequence-specific DNA binding
GHT02_RS22095	COG2855	membrane
GHT02_RS22100	COG0583	DNA-binding transcription factor activity
GHT02_RS22105	COG0833	amino acid
GHT02_RS22110	COG4771	TonB-dependent receptor
GHT02_RS22115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GHT02_RS22125	COG2311	Membrane
GHT02_RS22130	COG1609	Transcriptional regulator
GHT02_RS22135	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS22140	COG1129	ABC transporter
GHT02_RS22145	COG4211	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS22150	COG0167	dihydroorotate dehydrogenase activity
GHT02_RS22150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GHT02_RS22155	COG0493	'glutamate synthase
GHT02_RS22165	COG2949	membrane
GHT02_RS22175	COG1346	cytolysis
GHT02_RS22185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHT02_RS22200	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS22205	COG0586	Pfam SNARE associated Golgi protein
GHT02_RS22215	COG1686	Belongs to the peptidase S11 family
GHT02_RS22220	COG0277	FAD linked oxidase domain protein
GHT02_RS22225	COG1472	Belongs to the glycosyl hydrolase 3 family
GHT02_RS22230	COG1732	Glycine betaine
GHT02_RS22235	COG1174	glycine betaine transport
GHT02_RS22240	COG1125	glycine betaine transport
GHT02_RS22245	COG1174	glycine betaine transport
GHT02_RS22255	COG0789	Transcriptional regulator
GHT02_RS22260	COG3275	phosphorelay sensor kinase activity
GHT02_RS22265	COG3279	Response regulator of the LytR AlgR family
GHT02_RS22270	COG4807	Protein conserved in bacteria
GHT02_RS22275	COG4808	Protein conserved in bacteria
GHT02_RS22280	COG4715	Zinc finger, swim domain protein
GHT02_RS22285	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GHT02_RS22290	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GHT02_RS22295	COG0714	Associated with various cellular activities
GHT02_RS22305	COG3831	ATPase activity
GHT02_RS22310	COG3831	ATPase activity
GHT02_RS22320	COG0489	protein tyrosine kinase activity
GHT02_RS22330	COG3539	Fimbrial protein
GHT02_RS22335	COG3121	Chaperone
GHT02_RS22340	COG3188	usher protein
GHT02_RS22345	COG3539	Fimbrial protein
GHT02_RS22350	COG5455	response to cobalt ion
GHT02_RS22370	COG0351	phosphomethylpyrimidine kinase
GHT02_RS22380	COG2188	Transcriptional regulator
GHT02_RS22385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHT02_RS22390	COG1397	ADP-ribosylglycohydrolase
GHT02_RS22395	COG2211	Major facilitator Superfamily
GHT02_RS22400	COG1830	Aldolase
GHT02_RS22415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS22420	COG3414	Phosphotransferase system galactitol-specific IIB component
GHT02_RS22425	COG3775	system Galactitol-specific IIC component
GHT02_RS22430	COG1063	alcohol dehydrogenase
GHT02_RS22450	COG0826	peptidase U32
GHT02_RS22460	COG3609	addiction module antidote protein, CC2985 family
GHT02_RS22470	COG0745	RESPONSE REGULATOR receiver
GHT02_RS22475	COG2205	protein histidine kinase activity
GHT02_RS22515	COG4245	von Willebrand factor, type A
GHT02_RS22520	COG0631	protein serine/threonine phosphatase activity
GHT02_RS22525	COG3779	Protein conserved in bacteria
GHT02_RS22530	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
GHT02_RS22535	COG0443	Heat shock 70 kDa protein
GHT02_RS22540	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GHT02_RS22545	COG5001	Diguanylate cyclase
GHT02_RS22545	COG5002	protein histidine kinase activity
GHT02_RS22545	COG3447	MASE1 domain protein
GHT02_RS22550	COG0572	uridine kinase
GHT02_RS22560	COG2982	Protein involved in outer membrane biogenesis
GHT02_RS22565	COG1253	flavin adenine dinucleotide binding
GHT02_RS22575	COG1596	polysaccharide export
GHT02_RS22580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHT02_RS22585	COG3206	protein involved in exopolysaccharide biosynthesis
GHT02_RS22585	COG0489	protein tyrosine kinase activity
GHT02_RS22590	COG0463	Glycosyl transferase, family 2
GHT02_RS22595	COG1045	serine acetyltransferase
GHT02_RS22600	COG0438	transferase activity, transferring glycosyl groups
GHT02_RS22610	COG1216	Glycosyl transferase, family 2
GHT02_RS22615	COG0110	maltose O-acetyltransferase activity
GHT02_RS22620	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GHT02_RS22625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GHT02_RS22630	COG1051	belongs to the nudix hydrolase family
GHT02_RS22635	COG0297	glycogen (starch) synthase activity
GHT02_RS22640	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GHT02_RS22640	COG0662	Cupin 2, conserved barrel domain protein
GHT02_RS22645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GHT02_RS22650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GHT02_RS22655	COG2244	polysaccharide biosynthetic process
GHT02_RS22660	COG2327	Polysaccharide pyruvyl transferase
GHT02_RS22665	COG0438	transferase activity, transferring glycosyl groups
GHT02_RS22675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GHT02_RS22680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GHT02_RS22685	COG0438	transferase activity, transferring glycosyl groups
GHT02_RS22685	COG0297	glycogen (starch) synthase activity
GHT02_RS22690	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GHT02_RS22695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GHT02_RS22700	COG1051	belongs to the nudix hydrolase family
GHT02_RS22705	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GHT02_RS22705	COG0662	Cupin 2, conserved barrel domain protein
GHT02_RS22710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GHT02_RS22745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GHT02_RS22750	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GHT02_RS22755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GHT02_RS22780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GHT02_RS22785	COG0131	Imidazoleglycerol-phosphate dehydratase
GHT02_RS22785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GHT02_RS22795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GHT02_RS22810	COG2161	toxin-antitoxin pair type II binding
GHT02_RS22815	COG4115	mRNA cleavage
GHT02_RS22820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GHT02_RS22825	COG0583	DNA-binding transcription factor activity
GHT02_RS22835	COG0531	amino acid
GHT02_RS22840	COG2391	methyltransferase activity
GHT02_RS22845	COG0425	Belongs to the sulfur carrier protein TusA family
GHT02_RS22850	COG2925	Exonuclease
GHT02_RS22855	COG1686	Belongs to the peptidase S11 family
GHT02_RS22865	COG1289	transmembrane transporter activity
GHT02_RS22910	COG2003	Belongs to the UPF0758 family
GHT02_RS22935	COG2020	methyltransferase activity
GHT02_RS22940	COG3468	outer membrane autotransporter barrel domain protein
GHT02_RS22950	COG4983	Phage plasmid primase, P4 family domain protein
GHT02_RS22990	COG3436	PFAM IS66 Orf2 family protein
GHT02_RS22995	COG2433	Pfam Transposase IS66
GHT02_RS23025	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GHT02_RS23040	COG1376	ErfK ybiS ycfS ynhG family protein
GHT02_RS23050	COG0583	DNA-binding transcription factor activity
GHT02_RS23055	COG0583	DNA-binding transcription factor activity
GHT02_RS23065	COG0534	Mate efflux family protein
GHT02_RS23075	COG0217	transcriptional regulatory protein
GHT02_RS23085	COG0477	Major facilitator Superfamily
GHT02_RS23100	COG4932	domain protein
GHT02_RS23100	COG2373	Large extracellular alpha-helical protein
GHT02_RS23100	COG1388	LysM domain
GHT02_RS23105	COG4771	TonB-dependent receptor
GHT02_RS23110	COG1021	2,3-dihydroxybenzoate-AMP ligase
GHT02_RS23130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GHT02_RS23130	COG3433	isochorismatase activity
GHT02_RS23130	COG2226	methyltransferase
GHT02_RS23145	COG1132	(ABC) transporter
GHT02_RS23150	COG2814	Major facilitator Superfamily
GHT02_RS23155	COG1169	isochorismate synthase
GHT02_RS23160	COG0582	viral genome integration into host DNA
GHT02_RS23175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GHT02_RS23180	COG0735	belongs to the Fur family
GHT02_RS23190	COG0523	cobalamin synthesis protein
GHT02_RS23215	COG0523	cobalamin synthesis protein
GHT02_RS23245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GHT02_RS23250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GHT02_RS23255	COG1121	(ABC) transporter
GHT02_RS23260	COG0803	Belongs to the bacterial solute-binding protein 9 family
GHT02_RS23265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GHT02_RS23275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GHT02_RS23305	COG0803	Belongs to the bacterial solute-binding protein 9 family
GHT02_RS23310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GHT02_RS23315	COG1121	(ABC) transporter
GHT02_RS23325	COG0582	viral genome integration into host DNA
GHT02_RS23345	COG3038	cytochrome b561
GHT02_RS23350	COG3443	Belongs to the bacterial solute-binding protein 9 family
GHT02_RS23365	COG2351	hydroxyisourate hydrolase activity
GHT02_RS23370	COG0745	RESPONSE REGULATOR receiver
GHT02_RS23375	COG2205	protein histidine kinase activity
GHT02_RS23390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GHT02_RS23400	COG1418	mRNA catabolic process
GHT02_RS23405	COG0270	DNA (cytosine-5-)-methyltransferase activity
GHT02_RS23410	COG3727	T/G mismatch-specific endonuclease activity
GHT02_RS23415	COG0697	spore germination
GHT02_RS23420	COG2354	Protein conserved in bacteria
GHT02_RS23425	COG5475	Uncharacterized small protein (DUF2158)
GHT02_RS23430	COG3706	GGDEF domain
GHT02_RS23450	COG2197	response regulator
GHT02_RS23455	COG1684	flagellar biosynthetic protein fliR
GHT02_RS23460	COG1987	bacterial-type flagellum assembly
GHT02_RS23465	COG1338	Plays a role in the flagellum-specific transport system
GHT02_RS23470	COG3190	flagellar
GHT02_RS23475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GHT02_RS23480	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GHT02_RS23485	COG1580	Controls the rotational direction of flagella during chemotaxis
GHT02_RS23490	COG3144	bacterial-type flagellum assembly
GHT02_RS23495	COG2882	bacterial-type flagellum organization
GHT02_RS23500	COG1157	protein secretion by the type III secretion system
GHT02_RS23505	COG1317	bacterial-type flagellum organization
GHT02_RS23510	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GHT02_RS23515	COG1766	The M ring may be actively involved in energy transduction
GHT02_RS23525	COG2135	peptidase activity
GHT02_RS23530	COG0425	Belongs to the sulfur carrier protein TusA family
GHT02_RS23535	COG2391	methyltransferase activity
GHT02_RS23545	COG0366	Alpha amylase catalytic
GHT02_RS23555	COG1516	flagellar protein fliS
GHT02_RS23570	COG1191	sigma factor activity
GHT02_RS23580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GHT02_RS23590	COG0765	amino acid transport
GHT02_RS23595	COG1126	abc transporter atp-binding protein
GHT02_RS23600	COG2197	response regulator
GHT02_RS23615	COG2197	response regulator
GHT02_RS23645	COG3318	Belongs to the UPF0149 family
GHT02_RS23645	COG3012	SEC-C Motif Domain Protein
GHT02_RS23650	COG0814	amino acid
GHT02_RS23660	COG1528	Iron-storage protein
GHT02_RS23680	COG1528	Iron-storage protein
GHT02_RS23685	COG1879	ABC-type sugar transport system periplasmic component
GHT02_RS23690	COG1129	ABC transporter
GHT02_RS23695	COG1172	Belongs to the binding-protein-dependent transport system permease family
GHT02_RS23700	COG1877	trehalose-phosphatase activity
GHT02_RS23710	COG0589	response to stress
GHT02_RS23725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GHT02_RS23730	COG1360	Flagellar Motor Protein
GHT02_RS23735	COG0643	Histidine kinase
GHT02_RS23735	COG2198	Histidine kinase
GHT02_RS23740	COG0835	chemotaxis
GHT02_RS23745	COG0840	transmembrane signaling receptor activity
GHT02_RS23750	COG0840	transmembrane signaling receptor activity
GHT02_RS23755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GHT02_RS23760	COG2201	protein-glutamate methylesterase activity
GHT02_RS23765	COG0745	RESPONSE REGULATOR receiver
GHT02_RS23770	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GHT02_RS23775	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GHT02_RS23780	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GHT02_RS23790	COG3755	Protein conserved in bacteria
GHT02_RS23800	COG3102	Protein conserved in bacteria
GHT02_RS23810	COG3005	denitrification pathway
GHT02_RS23815	COG0243	molybdopterin cofactor binding
GHT02_RS23830	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GHT02_RS23835	COG1801	Protein of unknown function DUF72
GHT02_RS23840	COG0582	viral genome integration into host DNA
GHT02_RS23850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHT02_RS23895	COG3756	Protein conserved in bacteria
GHT02_RS23905	COG1846	Transcriptional regulator
GHT02_RS23960	COG1403	HNH endonuclease
GHT02_RS23965	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GHT02_RS23970	COG0484	heat shock protein binding
GHT02_RS24100	COG5301	cellulose 1,4-beta-cellobiosidase activity
GHT02_RS24115	COG3328	transposase activity
GHT02_RS24125	COG1335	isochorismatase
GHT02_RS24135	COG0494	nUDIX hydrolase
GHT02_RS24140	COG0217	transcriptional regulatory protein
GHT02_RS24170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GHT02_RS24180	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GHT02_RS24185	COG0739	heme binding
GHT02_RS24190	COG1560	Kdo2-lipid A biosynthetic process
GHT02_RS24195	COG0469	pyruvate kinase activity
GHT02_RS24200	COG1737	Transcriptional regulator
GHT02_RS24205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GHT02_RS24210	COG0129	dihydroxy-acid dehydratase activity
GHT02_RS24215	COG0800	Aldolase
GHT02_RS24225	COG3141	response to X-ray
GHT02_RS24235	COG2979	Protein of unknown function (DUF533)
GHT02_RS24240	COG1770	oligopeptidase
GHT02_RS24245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHT02_RS24250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GHT02_RS24260	COG2372	response to copper ion
GHT02_RS24265	COG1276	copper resistance
GHT02_RS24275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GHT02_RS24295	COG3008	intermembrane lipid transfer
GHT02_RS24300	COG2995	paraquat-inducible protein a
GHT02_RS24305	COG1956	GAF domain-containing protein
GHT02_RS24315	COG0793	Belongs to the peptidase S41A family
GHT02_RS24325	COG2814	Major facilitator Superfamily
GHT02_RS24330	COG1414	Transcriptional regulator
GHT02_RS24360	COG2226	methyltransferase
GHT02_RS24375	COG3716	PTS system mannose fructose sorbose family IID component
GHT02_RS24380	COG3715	PTS system
GHT02_RS24385	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GHT02_RS24385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS24390	COG1253	flavin adenine dinucleotide binding
GHT02_RS24395	COG2200	EAL domain
GHT02_RS24400	COG1760	l-serine dehydratase
GHT02_RS24410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GHT02_RS24425	COG0251	oxidation-reduction process
GHT02_RS24430	COG1199	ATP-dependent helicase activity
GHT02_RS24435	COG1214	PFAM Peptidase M22, glycoprotease
GHT02_RS24440	COG3065	identical protein binding
GHT02_RS24445	COG0318	PFAM AMP-dependent synthetase and ligase
GHT02_RS24450	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GHT02_RS24455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GHT02_RS24460	COG4638	Rieske (2fe-2S)
GHT02_RS24465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GHT02_RS24470	COG0473	3-isopropylmalate dehydrogenase activity
GHT02_RS24475	COG0583	DNA-binding transcription factor activity
GHT02_RS24485	COG3615	Tellurite resistance protein tehB
GHT02_RS24500	COG0675	Transposase, IS605 OrfB family
GHT02_RS24505	COG2261	transglycosylase associated protein
GHT02_RS24520	COG2199	diguanylate cyclase activity
GHT02_RS24520	COG2203	Gaf domain
GHT02_RS24525	COG3042	response to heat
GHT02_RS24530	COG3189	MarR family transcriptional regulator
GHT02_RS24535	COG2807	transmembrane transport
GHT02_RS24540	COG2207	Transcriptional regulator
GHT02_RS24555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GHT02_RS24560	COG2199	diguanylate cyclase activity
GHT02_RS24565	COG2199	diguanylate cyclase activity
GHT02_RS24575	COG2766	serine protein kinase
GHT02_RS24580	COG3713	MltA-interacting MipA family protein
GHT02_RS24585	COG0656	L-ascorbic acid biosynthetic process
GHT02_RS24590	COG0676	glucose-6-phosphate 1-epimerase activity
GHT02_RS24595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GHT02_RS24605	COG3139	Protein of unknown function (DUF1315)
GHT02_RS24610	COG1335	isochorismatase
GHT02_RS24615	COG0252	asparaginase activity
GHT02_RS24620	COG0616	signal peptide processing
GHT02_RS24625	COG0778	Nitroreductase
GHT02_RS24635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHT02_RS24645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GHT02_RS24655	COG0494	nUDIX hydrolase
GHT02_RS24660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHT02_RS24665	COG2897	thiosulfate sulfurtransferase activity
GHT02_RS24670	COG4136	ATPase activity
GHT02_RS24675	COG4135	transport system, permease component
GHT02_RS24680	COG4134	Bacterial extracellular solute-binding protein
GHT02_RS24685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GHT02_RS24690	COG0398	Pfam SNARE associated Golgi protein
GHT02_RS24700	COG0398	Pfam SNARE associated Golgi protein
GHT02_RS24705	COG0708	Exodeoxyribonuclease III
GHT02_RS24735	COG3678	ATP-independent chaperone mediated protein folding
GHT02_RS24745	COG0322	excinuclease ABC activity
GHT02_RS24755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GHT02_RS24760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GHT02_RS24765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GHT02_RS24770	COG1447	Phosphotransferase system cellobiose-specific component IIA
GHT02_RS24775	COG1917	Cupin 2, conserved barrel domain protein
GHT02_RS24775	COG2169	Transcriptional regulator
GHT02_RS24780	COG1486	melibiose metabolic process
GHT02_RS24790	COG0753	catalase activity
GHT02_RS24810	COG1823	symporter activity
GHT02_RS24815	COG1988	membrane-bound metal-dependent
GHT02_RS24820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GHT02_RS24830	COG3001	Fructosamine kinase
GHT02_RS24840	COG1105	Belongs to the carbohydrate kinase PfkB family
GHT02_RS24845	COG3137	Salt-induced outer membrane protein
GHT02_RS24905	COG0386	Belongs to the glutathione peroxidase family
GHT02_RS24915	COG0791	NLP P60 protein
GHT02_RS24920	COG2200	EAL domain
GHT02_RS24930	COG4256	Hemin uptake protein
GHT02_RS24935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHT02_RS24945	COG0574	Belongs to the PEP-utilizing enzyme family
GHT02_RS24945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHT02_RS24950	COG0318	PFAM AMP-dependent synthetase and ligase
GHT02_RS24955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GHT02_RS24960	COG0644	oxidoreductase
GHT02_RS24965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GHT02_RS24970	COG2086	electron transfer activity
GHT02_RS24975	COG2207	Transcriptional regulator
GHT02_RS24975	COG1917	Cupin 2, conserved barrel domain protein
GHT02_RS24980	COG1960	acyl-CoA dehydrogenase activity
GHT02_RS24985	COG4670	ketone body catabolic process
GHT02_RS25000	COG2271	Major facilitator Superfamily
GHT02_RS25005	COG0738	Major facilitator superfamily
GHT02_RS25020	COG0628	permease
GHT02_RS25025	COG0247	lactate metabolic process
GHT02_RS25025	COG0277	FAD linked oxidase domain protein
GHT02_RS25030	COG2050	protein possibly involved in aromatic compounds catabolism
GHT02_RS25040	COG0316	Belongs to the HesB IscA family
GHT02_RS25045	COG0719	Fe-S assembly protein
GHT02_RS25050	COG0396	ATPase activity
GHT02_RS25055	COG0719	Fe-S assembly protein
GHT02_RS25070	COG1376	ErfK ybiS ycfS ynhG family protein
GHT02_RS25075	COG4238	major outer membrane lipoprotein
GHT02_RS25080	COG0469	pyruvate kinase activity
GHT02_RS25090	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS25095	COG2414	aldehyde ferredoxin oxidoreductase
GHT02_RS25105	COG0437	4 iron, 4 sulfur cluster binding
GHT02_RS25110	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GHT02_RS25120	COG4529	Protein conserved in bacteria
GHT02_RS25140	COG3468	outer membrane autotransporter barrel domain protein
GHT02_RS25150	COG0307	riboflavin synthase, alpha
GHT02_RS25155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GHT02_RS25160	COG2814	Major facilitator Superfamily
GHT02_RS25165	COG0583	DNA-binding transcription factor activity
GHT02_RS25180	COG2814	Major facilitator Superfamily
GHT02_RS25185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GHT02_RS25190	COG0791	NLP P60 protein
GHT02_RS25195	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GHT02_RS25200	COG1201	RNA secondary structure unwinding
GHT02_RS25210	COG0346	lactoylglutathione lyase activity
GHT02_RS25215	COG1902	pentaerythritol trinitrate reductase activity
GHT02_RS25220	COG1309	transcriptional regulator
GHT02_RS25225	COG3313	Fe-S protein
GHT02_RS25235	COG4989	oxidoreductase activity
GHT02_RS25240	COG2032	superoxide dismutase activity
GHT02_RS25245	COG1289	transmembrane transporter activity
GHT02_RS25250	COG1566	PFAM secretion protein HlyD family protein
GHT02_RS25265	COG3133	Outer membrane lipoprotein
GHT02_RS25275	COG3895	Periplasmic Protein
GHT02_RS25290	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GHT02_RS25295	COG0625	glutathione transferase activity
GHT02_RS25300	COG3104	oligopeptide transport
GHT02_RS25305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GHT02_RS25315	COG4659	FMN binding
GHT02_RS25355	COG0673	inositol 2-dehydrogenase activity
GHT02_RS25365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GHT02_RS25370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GHT02_RS25370	COG1263	PTS System
GHT02_RS25375	COG1609	Transcriptional regulator
GHT02_RS25380	COG1028	Short-chain dehydrogenase reductase Sdr
GHT02_RS25385	COG1309	transcriptional regulator
GHT02_RS25390	COG3250	beta-galactosidase activity
GHT02_RS25405	COG5339	Protein conserved in bacteria
GHT02_RS25410	COG1482	cell wall glycoprotein biosynthetic process
GHT02_RS25415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GHT02_RS25415	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GHT02_RS25420	COG0114	fumarate hydratase activity
GHT02_RS25430	COG2205	protein histidine kinase activity
GHT02_RS25435	COG0745	RESPONSE REGULATOR receiver
GHT02_RS25440	COG3136	membrane protein required for alginate biosynthesis
GHT02_RS25450	COG0531	amino acid
GHT02_RS25460	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GHT02_RS25465	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GHT02_RS25470	COG0628	permease
GHT02_RS25485	COG3591	Belongs to the peptidase S1B family
GHT02_RS25500	COG2814	Major facilitator Superfamily
GHT02_RS25505	COG0583	DNA-binding transcription factor activity
GHT02_RS25510	COG1940	carbohydrate kinase activity
GHT02_RS25515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GHT02_RS25525	COG3381	protein complex oligomerization
GHT02_RS25530	COG3302	dmso reductase anchor subunit
GHT02_RS25540	COG0582	viral genome integration into host DNA
GHT02_RS25570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHT02_RS25650	COG1484	DNA-dependent DNA replication
GHT02_RS25655	COG1846	Transcriptional regulator
GHT02_RS25755	COG3772	lysozyme
GHT02_RS25790	COG4571	Outer membrane protease
GHT02_RS25895	COG1475	DNA binding
GHT02_RS26100	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GHT02_RS26145	COG3041	Addiction module toxin RelE StbE family
GHT02_RS26180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHT02_RS26190	COG2819	hydrolase of the alpha beta superfamily
GHT02_RS26195	COG2382	esterase
GHT02_RS26255	COG1538	Outer membrane efflux protein
GHT02_RS26265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHT02_RS26395	COG3835	regulator
GHT02_RS26400	COG2610	gluconate transmembrane transporter activity
GHT02_RS26405	COG1929	Belongs to the glycerate kinase type-1 family
GHT02_RS26420	COG2814	Major facilitator Superfamily
GHT02_RS26480	COG1051	belongs to the nudix hydrolase family
GHT02_RS26490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GHT02_RS26505	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
GHT02_RS26525	COG0671	phosphoesterase, PA-phosphatase related
GHT02_RS26525	COG2453	phosphatase
GHT02_RS26530	COG2267	carboxylic ester hydrolase activity
GHT02_RS26540	COG4589	Belongs to the CDS family
GHT02_RS26745	COG1475	DNA binding
GHT02_RS27025	COG4771	TonB-dependent receptor
GHT02_RS27070	COG0741	lytic transglycosylase activity
GHT02_RS27125	COG1192	Involved in chromosome partitioning
GHT02_RS27150	COG3620	sequence-specific DNA binding
GHT02_RS27200	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
GHT02_RS27310	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source