locus-tag	class	description
FP497_RS00010	COG0592	DNA-directed DNA polymerase activity
FP497_RS00020	COG0187	DNA topoisomerase II activity
FP497_RS00025	COG3753	Protein conserved in bacteria
FP497_RS00030	COG0561	phosphatase activity
FP497_RS00040	COG2186	Transcriptional regulator
FP497_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
FP497_RS00050	COG0800	Aldolase
FP497_RS00060	COG2271	Major facilitator Superfamily
FP497_RS00065	COG0644	oxidoreductase
FP497_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
FP497_RS00075	COG5645	(Lipo)protein
FP497_RS00095	COG2188	Transcriptional regulator
FP497_RS00100	COG1263	PTS System
FP497_RS00105	COG1263	PTS System
FP497_RS00105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS00115	COG2207	Transcriptional regulator
FP497_RS00120	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FP497_RS00125	COG3119	arylsulfatase activity
FP497_RS00135	COG2149	membrane
FP497_RS00145	COG0641	radical SAM
FP497_RS00150	COG2814	Major facilitator Superfamily
FP497_RS00165	COG0028	Belongs to the TPP enzyme family
FP497_RS00170	COG0440	acetolactate synthase activity
FP497_RS00175	COG2197	response regulator
FP497_RS00180	COG3851	Histidine kinase
FP497_RS00185	COG2271	Major facilitator Superfamily
FP497_RS00190	COG2271	Major facilitator Superfamily
FP497_RS00200	COG2252	PERMEase
FP497_RS00220	COG1464	Belongs to the NlpA lipoprotein family
FP497_RS00225	COG0697	spore germination
FP497_RS00230	COG2814	Major facilitator Superfamily
FP497_RS00245	COG2211	Major facilitator Superfamily
FP497_RS00250	COG1501	Belongs to the glycosyl hydrolase 31 family
FP497_RS00255	COG2982	Protein involved in outer membrane biogenesis
FP497_RS00260	COG2233	PERMEase
FP497_RS00265	COG0786	glutamate:sodium symporter activity
FP497_RS00270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FP497_RS00275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FP497_RS00280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FP497_RS00290	COG0194	GDP metabolic process
FP497_RS00300	COG2860	membrane
FP497_RS00305	COG3645	SOS response
FP497_RS00310	COG1561	YicC-like family, N-terminal region
FP497_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FP497_RS00365	COG1519	Transferase
FP497_RS00370	COG0859	PFAM glycosyl transferase family 9
FP497_RS00375	COG0438	transferase activity, transferring glycosyl groups
FP497_RS00380	COG0515	serine threonine protein kinase
FP497_RS00395	COG1442	glycosyl transferase family 8
FP497_RS00405	COG3642	lipopolysaccharide core region biosynthetic process
FP497_RS00420	COG3307	-O-antigen
FP497_RS00425	COG0859	PFAM glycosyl transferase family 9
FP497_RS00430	COG0859	PFAM glycosyl transferase family 9
FP497_RS00445	COG0156	8-amino-7-oxononanoate synthase activity
FP497_RS00455	COG1216	Glycosyl transferase, family 2
FP497_RS00460	COG2861	carbohydrate metabolic process
FP497_RS00465	COG4942	peptidase
FP497_RS00470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FP497_RS00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FP497_RS00480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FP497_RS00495	COG1045	serine acetyltransferase
FP497_RS00500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FP497_RS00510	COG2186	Transcriptional regulator
FP497_RS00515	COG1620	l-lactate permease
FP497_RS00530	COG3722	fumarate hydratase activity
FP497_RS00540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS00540	COG2213	PTS system mannitol-specific
FP497_RS00550	COG1566	PFAM secretion protein HlyD family protein
FP497_RS00555	COG0625	glutathione transferase activity
FP497_RS00565	COG3276	selenocysteine insertion sequence binding
FP497_RS00570	COG1454	alcohol dehydrogenase
FP497_RS00575	COG1012	belongs to the aldehyde dehydrogenase family
FP497_RS00590	COG1566	PFAM secretion protein HlyD family protein
FP497_RS00595	COG0583	DNA-binding transcription factor activity
FP497_RS00600	COG3713	MltA-interacting MipA family protein
FP497_RS00610	COG0235	Class ii aldolase
FP497_RS00615	COG3623	hexulose-6-phosphate isomerase
FP497_RS00620	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FP497_RS00625	COG1070	Carbohydrate kinase
FP497_RS00630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FP497_RS00635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FP497_RS00640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FP497_RS00645	COG2731	YhcH YjgK YiaL family protein
FP497_RS00655	COG1414	Transcriptional regulator
FP497_RS00660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS00665	COG3977	Valine--pyruvate aminotransferase
FP497_RS00670	COG0366	Alpha amylase catalytic
FP497_RS00675	COG2992	FlgJ-related protein
FP497_RS00680	COG1609	Transcriptional regulator
FP497_RS00680	COG2207	Transcriptional regulator
FP497_RS00685	COG4214	carbohydrate transport
FP497_RS00690	COG1129	ABC transporter
FP497_RS00695	COG4213	ABC transporter substrate-binding protein
FP497_RS00705	COG1070	Carbohydrate kinase
FP497_RS00710	COG4682	membrane
FP497_RS00715	COG4682	membrane
FP497_RS00720	COG3274	enterobacterial common antigen metabolic process
FP497_RS00730	COG0752	glycyl-tRNA synthetase alpha subunit
FP497_RS00745	COG1278	Cold shock
FP497_RS00750	COG2944	sequence-specific DNA binding
FP497_RS00765	COG2885	chlorophyll binding
FP497_RS00770	COG0243	molybdopterin cofactor binding
FP497_RS00775	COG0456	acetyltransferase
FP497_RS00780	COG2818	Glycosylase
FP497_RS00785	COG5571	outer membrane autotransporter
FP497_RS00790	COG2223	nitrite transmembrane transporter activity
FP497_RS00795	COG2194	sulfuric ester hydrolase activity
FP497_RS00810	COG0747	negative chemotaxis
FP497_RS00820	COG0601	transmembrane transport
FP497_RS00825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FP497_RS00830	COG0444	Belongs to the ABC transporter superfamily
FP497_RS00835	COG4608	Belongs to the ABC transporter superfamily
FP497_RS00840	COG0814	amino acid
FP497_RS00855	COG2194	sulfuric ester hydrolase activity
FP497_RS00880	COG1215	transferase activity, transferring glycosyl groups
FP497_RS00885	COG1215	transferase activity, transferring glycosyl groups
FP497_RS00890	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FP497_RS00895	COG0457	Tetratricopeptide repeat
FP497_RS00895	COG3118	belongs to the thioredoxin family
FP497_RS00900	COG2199	diguanylate cyclase activity
FP497_RS00900	COG2200	EAL domain
FP497_RS00910	COG0612	Peptidase, M16
FP497_RS00915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS00920	COG2200	EAL domain
FP497_RS00925	COG2982	Protein involved in outer membrane biogenesis
FP497_RS00930	COG0477	Major facilitator Superfamily
FP497_RS00935	COG1295	ribonuclease BN
FP497_RS00940	COG0583	DNA-binding transcription factor activity
FP497_RS00945	COG2197	response regulator
FP497_RS00955	COG1858	cytochrome C peroxidase
FP497_RS00960	COG0076	glutamate decarboxylase activity
FP497_RS00965	COG2207	Transcriptional regulator
FP497_RS00970	COG2207	Transcriptional regulator
FP497_RS00975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FP497_RS00980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FP497_RS00990	COG2771	luxR family
FP497_RS00995	COG3247	response to pH
FP497_RS01010	COG1285	pathogenesis
FP497_RS01015	COG2197	response regulator
FP497_RS01020	COG3065	identical protein binding
FP497_RS01025	COG1393	Belongs to the ArsC family
FP497_RS01030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FP497_RS01035	COG0640	Transcriptional regulator
FP497_RS01045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FP497_RS01050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FP497_RS01055	COG0339	signal peptide processing
FP497_RS01065	COG3104	oligopeptide transport
FP497_RS01070	COG0589	response to stress
FP497_RS01080	COG0306	phosphate transporter
FP497_RS01085	COG2081	HI0933 family
FP497_RS01105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FP497_RS01110	COG0842	Transport permease protein
FP497_RS01110	COG1129	ABC transporter
FP497_RS01115	COG0842	Transport permease protein
FP497_RS01125	COG1124	(ABC) transporter
FP497_RS01130	COG0444	Belongs to the ABC transporter superfamily
FP497_RS01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FP497_RS01140	COG0601	transmembrane transport
FP497_RS01145	COG0747	negative chemotaxis
FP497_RS01150	COG2091	lysine biosynthetic process via aminoadipic acid
FP497_RS01155	COG0628	permease
FP497_RS01160	COG0477	Major facilitator Superfamily
FP497_RS01170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FP497_RS01180	COG2217	Heavy metal translocating P-type atpase
FP497_RS01185	COG3714	YhhN family
FP497_RS01195	COG3776	membrane
FP497_RS01200	COG0742	ribosomal rna small subunit methyltransferase
FP497_RS01205	COG0552	protein localization to endoplasmic reticulum
FP497_RS01210	COG2884	Cell division ATP-binding protein ftsE
FP497_RS01215	COG2177	Part of the ABC transporter FtsEX involved in
FP497_RS01220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FP497_RS01225	COG0683	leucine binding
FP497_RS01230	COG0456	acetyltransferase
FP497_RS01235	COG0683	leucine binding
FP497_RS01240	COG0559	Belongs to the binding-protein-dependent transport system permease family
FP497_RS01245	COG4177	L-phenylalanine transmembrane transporter activity
FP497_RS01250	COG0411	ABC transporter
FP497_RS01255	COG0410	ABC transporter
FP497_RS01260	COG1653	transport
FP497_RS01265	COG1175	transmembrane transport
FP497_RS01270	COG0395	ABC-type sugar transport system, permease component
FP497_RS01275	COG3842	ATPase activity
FP497_RS01280	COG0584	glycerophosphoryl diester phosphodiesterase
FP497_RS01290	COG0405	Gamma-glutamyltransferase
FP497_RS01300	COG0673	inositol 2-dehydrogenase activity
FP497_RS01305	COG1741	Belongs to the pirin family
FP497_RS01310	COG1609	Transcriptional regulator
FP497_RS01315	COG3265	gluconokinase activity
FP497_RS01320	COG2610	gluconate transmembrane transporter activity
FP497_RS01325	COG2095	MarC family integral membrane protein
FP497_RS01330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FP497_RS01355	COG0058	SHG alpha-glucan phosphorylase activity
FP497_RS01365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FP497_RS01385	COG4650	regulator
FP497_RS01390	COG1690	Belongs to the RtcB family
FP497_RS01405	COG0058	SHG alpha-glucan phosphorylase activity
FP497_RS01410	COG1640	4-alpha-glucanotransferase
FP497_RS01415	COG2610	gluconate transmembrane transporter activity
FP497_RS01425	COG1040	competence protein
FP497_RS01435	COG5464	transposase or invertase
FP497_RS01445	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FP497_RS01450	COG1918	ferrous iron import across plasma membrane
FP497_RS01455	COG2183	response to ionizing radiation
FP497_RS01460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FP497_RS01480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FP497_RS01490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FP497_RS01495	COG1011	Hydrolase
FP497_RS01505	COG0494	nUDIX hydrolase
FP497_RS01510	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FP497_RS01515	COG4972	Pilus assembly protein
FP497_RS01520	COG3166	PFAM Fimbrial assembly family protein
FP497_RS01535	COG4796	Type ii and iii secretion system protein
FP497_RS01550	COG3266	domain, Protein
FP497_RS01555	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FP497_RS01560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FP497_RS01565	COG0546	phosphoglycolate phosphatase activity
FP497_RS01570	COG0180	Tryptophanyl-tRNA synthetase
FP497_RS01580	COG2188	Transcriptional regulator
FP497_RS01590	COG3457	Alanine racemase
FP497_RS01595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FP497_RS01600	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FP497_RS01615	COG0626	cystathionine gamma-synthase activity
FP497_RS01620	COG2188	Transcriptional regulator
FP497_RS01625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS01630	COG1082	Xylose isomerase domain protein TIM barrel
FP497_RS01635	COG2222	sugar isomerase
FP497_RS01640	COG0531	amino acid
FP497_RS01655	COG2116	formate transmembrane transporter activity
FP497_RS01660	COG2146	nitrite reductase [NAD(P)H] activity
FP497_RS01665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FP497_RS01675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FP497_RS01685	COG2184	nucleotidyltransferase activity
FP497_RS01690	COG0512	Glutamine amidotransferase of anthranilate synthase
FP497_RS01695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FP497_RS01700	COG1289	transmembrane transporter activity
FP497_RS01705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FP497_RS01710	COG1765	OsmC-like protein
FP497_RS01715	COG3954	Phosphoribulokinase
FP497_RS01725	COG0429	hydrolase of the alpha beta-hydrolase fold
FP497_RS01730	COG0488	(ABC) transporter
FP497_RS01745	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FP497_RS01750	COG1047	Peptidyl-prolyl cis-trans
FP497_RS01760	COG0545	Peptidyl-prolyl cis-trans isomerase
FP497_RS01765	COG2964	Protein conserved in bacteria
FP497_RS01825	COG0089	rRNA binding
FP497_RS01915	COG0201	protein transport
FP497_RS01955	COG0789	Transcriptional regulator
FP497_RS01960	COG3036	rescue of stalled ribosome
FP497_RS01970	COG0569	domain protein
FP497_RS01990	COG0758	DNA mediated transformation
FP497_RS02000	COG0551	DNA topoisomerase type I activity
FP497_RS02020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FP497_RS02065	COG1126	abc transporter atp-binding protein
FP497_RS02070	COG0765	amino acid transport
FP497_RS02075	COG4597	amino acid ABC transporter
FP497_RS02090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FP497_RS02095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FP497_RS02100	COG1309	transcriptional regulator
FP497_RS02110	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FP497_RS02120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FP497_RS02130	COG4145	pantothenate transmembrane transporter activity
FP497_RS02135	COG3924	membrane
FP497_RS02140	COG0439	Biotin carboxylase
FP497_RS02145	COG0511	ligase activity, forming carbon-carbon bonds
FP497_RS02150	COG0604	alcohol dehydrogenase
FP497_RS02155	COG2200	EAL domain
FP497_RS02155	COG2199	diguanylate cyclase activity
FP497_RS02160	COG1077	Cell shape determining protein MreB Mrl
FP497_RS02165	COG1792	Involved in formation and maintenance of cell shape
FP497_RS02170	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FP497_RS02175	COG0424	maF-like protein
FP497_RS02180	COG1530	ribonuclease E activity
FP497_RS02185	COG3164	Protein of unknown function
FP497_RS02190	COG0312	modulator of DNA gyrase
FP497_RS02195	COG0583	DNA-binding transcription factor activity
FP497_RS02210	COG1289	transmembrane transporter activity
FP497_RS02215	COG2732	(Barnase) inhibitor
FP497_RS02235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FP497_RS02240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FP497_RS02245	COG3105	Protein conserved in bacteria
FP497_RS02250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FP497_RS02265	COG0625	glutathione transferase activity
FP497_RS02270	COG2969	positive regulation of protein catabolic process
FP497_RS02275	COG3069	C4-dicarboxylate transmembrane transporter activity
FP497_RS02305	COG2731	YhcH YjgK YiaL family protein
FP497_RS02310	COG4804	nuclease activity
FP497_RS02315	COG3539	Fimbrial protein
FP497_RS02320	COG0493	'glutamate synthase
FP497_RS02325	COG0070	glutamate synthase
FP497_RS02325	COG0067	glutamate synthase
FP497_RS02325	COG0069	glutamate synthase activity
FP497_RS02330	COG1242	4 iron, 4 sulfur cluster binding
FP497_RS02335	COG0784	Response regulator, receiver
FP497_RS02335	COG2198	Histidine kinase
FP497_RS02335	COG5002	protein histidine kinase activity
FP497_RS02340	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FP497_RS02350	COG0515	serine threonine protein kinase
FP497_RS02355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS02370	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FP497_RS02375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FP497_RS02380	COG1137	ATPase activity
FP497_RS02385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FP497_RS02390	COG3117	lipopolysaccharide transmembrane transporter activity
FP497_RS02395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FP497_RS02400	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FP497_RS02400	COG0517	IMP dehydrogenase activity
FP497_RS02405	COG0530	calcium, potassium:sodium antiporter activity
FP497_RS02410	COG1127	ABC transporter
FP497_RS02415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FP497_RS02420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FP497_RS02425	COG2854	intermembrane phospholipid transfer
FP497_RS02430	COG3113	response to antibiotic
FP497_RS02435	COG5007	Belongs to the BolA IbaG family
FP497_RS02445	COG3423	Transcriptional regulator
FP497_RS02450	COG0142	geranyltranstransferase activity
FP497_RS02465	COG0697	spore germination
FP497_RS02475	COG2027	D-alanyl-D-alanine carboxypeptidase
FP497_RS02480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FP497_RS02485	COG1534	Rna-binding protein
FP497_RS02495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FP497_RS02500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FP497_RS02510	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FP497_RS02520	COG2194	sulfuric ester hydrolase activity
FP497_RS02540	COG0195	Participates in both transcription termination and antitermination
FP497_RS02580	COG0513	Belongs to the DEAD box helicase family
FP497_RS02585	COG0814	amino acid
FP497_RS02590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FP497_RS02595	COG0826	peptidase U32
FP497_RS02600	COG0826	peptidase U32
FP497_RS02605	COG3154	lipid carrier protein
FP497_RS02610	COG3153	acetyltransferase
FP497_RS02625	COG0693	protein deglycase activity
FP497_RS02630	COG0702	epimerase
FP497_RS02635	COG0701	Predicted permease
FP497_RS02640	COG2823	Periplasmic or secreted lipoprotein
FP497_RS02655	COG3107	peptidoglycan biosynthetic process
FP497_RS02660	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FP497_RS02665	COG3539	Fimbrial protein
FP497_RS02670	COG3188	usher protein
FP497_RS02675	COG3121	Chaperone
FP497_RS02680	COG3539	Fimbrial protein
FP497_RS02685	COG0363	glucosamine-6-phosphate deaminase activity
FP497_RS02690	COG3716	PTS system mannose fructose sorbose family IID component
FP497_RS02695	COG3715	PTS system
FP497_RS02700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS02710	COG2222	sugar isomerase
FP497_RS02725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS02735	COG1349	DNA-binding transcription factor activity
FP497_RS02745	COG2002	toxin-antitoxin pair type II binding
FP497_RS02750	COG2721	sulfolactate sulfo-lyase activity
FP497_RS02755	COG2271	Major facilitator Superfamily
FP497_RS02765	COG2084	Dehydrogenase
FP497_RS02770	COG1929	Belongs to the glycerate kinase type-1 family
FP497_RS02795	COG0583	DNA-binding transcription factor activity
FP497_RS02800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FP497_RS02810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FP497_RS02815	COG1882	Formate acetyltransferase
FP497_RS02820	COG0251	oxidation-reduction process
FP497_RS02825	COG1760	l-serine dehydratase
FP497_RS02830	COG0814	amino acid
FP497_RS02845	COG1741	Belongs to the pirin family
FP497_RS02850	COG0583	DNA-binding transcription factor activity
FP497_RS02855	COG3152	Membrane
FP497_RS02860	COG3152	Membrane
FP497_RS02865	COG0435	Glutathione S-transferase
FP497_RS02870	COG2259	Doxx family
FP497_RS02880	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FP497_RS02885	COG4575	ribosome binding
FP497_RS02890	COG1422	Protein of unknown function (DUF1090)
FP497_RS02900	COG0586	Pfam SNARE associated Golgi protein
FP497_RS02905	COG2186	Transcriptional regulator
FP497_RS02910	COG2271	Major facilitator Superfamily
FP497_RS02920	COG2721	sulfolactate sulfo-lyase activity
FP497_RS02930	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FP497_RS02935	COG0861	Integral membrane protein TerC family
FP497_RS02940	COG0673	inositol 2-dehydrogenase activity
FP497_RS02945	COG2949	membrane
FP497_RS02950	COG1451	nucleotide metabolic process
FP497_RS02960	COG4680	protein conserved in bacteria
FP497_RS02965	COG5499	transcription regulator containing HTH domain
FP497_RS02970	COG1902	pentaerythritol trinitrate reductase activity
FP497_RS02970	COG0446	pyridine nucleotide-disulphide oxidoreductase
FP497_RS02975	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FP497_RS02975	COG3408	Glycogen debranching enzyme
FP497_RS02985	COG0531	amino acid
FP497_RS02990	COG2731	YhcH YjgK YiaL family protein
FP497_RS02995	COG3250	beta-galactosidase activity
FP497_RS03000	COG1609	Transcriptional regulator
FP497_RS03005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FP497_RS03015	COG0840	transmembrane signaling receptor activity
FP497_RS03020	COG1695	Transcriptional regulator
FP497_RS03025	COG2375	cellular response to nickel ion
FP497_RS03040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FP497_RS03045	COG0358	DNA primase activity
FP497_RS03050	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FP497_RS03060	COG0471	metal ion transport
FP497_RS03065	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FP497_RS03070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FP497_RS03075	COG0583	DNA-binding transcription factor activity
FP497_RS03085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FP497_RS03100	COG4991	sh3 domain protein
FP497_RS03105	COG3025	triphosphatase activity
FP497_RS03130	COG2268	Band 7 protein
FP497_RS03135	COG1585	Membrane protein implicated in regulation of membrane protease activity
FP497_RS03155	COG3384	dioxygenase
FP497_RS03160	COG0754	glutathionylspermidine amidase activity
FP497_RS03170	COG1538	Outer membrane efflux protein
FP497_RS03175	COG0494	nUDIX hydrolase
FP497_RS03180	COG3151	Protein conserved in bacteria
FP497_RS03185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FP497_RS03190	COG3150	esterase
FP497_RS03195	COG0187	DNA topoisomerase II activity
FP497_RS03200	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FP497_RS03205	COG2249	NAD(P)H dehydrogenase (quinone) activity
FP497_RS03215	COG0642	Histidine kinase
FP497_RS03220	COG0745	RESPONSE REGULATOR receiver
FP497_RS03225	COG3111	PFAM Bacterial OB fold (BOF) protein
FP497_RS03230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FP497_RS03240	COG2944	sequence-specific DNA binding
FP497_RS03245	COG4166	transmembrane transport
FP497_RS03250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FP497_RS03255	COG0204	Acyl-transferase
FP497_RS03260	COG2132	Multicopper oxidase
FP497_RS03265	COG1032	radical SAM domain protein
FP497_RS03270	COG4238	major outer membrane lipoprotein
FP497_RS03280	COG0656	L-ascorbic acid biosynthetic process
FP497_RS03285	COG1979	alcohol dehydrogenase
FP497_RS03290	COG2207	Transcriptional regulator
FP497_RS03295	COG0586	Pfam SNARE associated Golgi protein
FP497_RS03300	COG0626	cystathionine gamma-synthase activity
FP497_RS03305	COG0811	peptide transport
FP497_RS03310	COG0848	biopolymer transport protein
FP497_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS03325	COG0667	Aldo Keto reductase
FP497_RS03340	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FP497_RS03345	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS03350	COG5557	Pfam Polysulphide reductase, NrfD
FP497_RS03355	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FP497_RS03360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FP497_RS03365	COG1773	rubredoxin
FP497_RS03375	COG0298	carbon dioxide binding
FP497_RS03380	COG0625	glutathione transferase activity
FP497_RS03385	COG0754	glutathionylspermidine amidase activity
FP497_RS03400	COG1811	Na channel or pump
FP497_RS03405	COG1982	Orn Lys Arg decarboxylase major
FP497_RS03410	COG2211	Major facilitator Superfamily
FP497_RS03425	COG1194	a g-specific adenine glycosylase
FP497_RS03435	COG3171	Protein conserved in bacteria
FP497_RS03445	COG0252	asparaginase activity
FP497_RS03455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FP497_RS03460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FP497_RS03470	COG0762	integral membrane protein
FP497_RS03475	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FP497_RS03480	COG2805	Type II/IV secretion system protein
FP497_RS03495	COG0189	ligase activity
FP497_RS03500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FP497_RS03510	COG2814	Major facilitator Superfamily
FP497_RS03525	COG1166	arginine decarboxylase activity
FP497_RS03535	COG0501	Belongs to the peptidase M48B family
FP497_RS03540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FP497_RS03545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS03550	COG2213	PTS system mannitol-specific
FP497_RS03555	COG1063	alcohol dehydrogenase
FP497_RS03560	COG1494	fructose-1,6-bisphosphatase
FP497_RS03565	COG3722	fumarate hydratase activity
FP497_RS03570	COG1072	(Pantothenic acid kinase))
FP497_RS03585	COG0191	fructose-bisphosphate aldolase activity
FP497_RS03590	COG0668	transmembrane transport
FP497_RS03595	COG1279	arginine transmembrane transporter activity
FP497_RS03600	COG2968	Membrane
FP497_RS03605	COG0583	DNA-binding transcription factor activity
FP497_RS03610	COG0427	acetyl-CoA hydrolase
FP497_RS03615	COG1024	Enoyl-CoA hydratase
FP497_RS03620	COG1703	isobutyryl-CoA mutase activity
FP497_RS03625	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FP497_RS03625	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FP497_RS03645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FP497_RS03655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FP497_RS03675	COG0006	proline dipeptidase activity
FP497_RS03680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FP497_RS03685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FP497_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS03715	COG2723	6-phospho-beta-galactosidase activity
FP497_RS03725	COG1272	protein, Hemolysin III
FP497_RS03735	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FP497_RS03745	COG0716	FMN binding
FP497_RS03750	COG4974	Belongs to the 'phage' integrase family
FP497_RS03755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FP497_RS03760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FP497_RS03770	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FP497_RS03790	COG2233	PERMEase
FP497_RS03795	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS03795	COG0493	'glutamate synthase
FP497_RS03800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS03805	COG2252	PERMEase
FP497_RS03810	COG0402	S-adenosylhomocysteine deaminase activity
FP497_RS03815	COG2233	PERMEase
FP497_RS03820	COG2080	2 iron, 2 sulfur cluster binding
FP497_RS03820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FP497_RS03825	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FP497_RS03830	COG0402	S-adenosylhomocysteine deaminase activity
FP497_RS03835	COG0493	'glutamate synthase
FP497_RS03835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS03840	COG2068	MobA-Related Protein
FP497_RS03845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FP497_RS03850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FP497_RS03850	COG3608	succinylglutamate desuccinylase aspartoacylase
FP497_RS03855	COG0549	Belongs to the carbamate kinase family
FP497_RS03865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FP497_RS03870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FP497_RS03875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FP497_RS03880	COG3829	transcription factor binding
FP497_RS03885	COG2080	2 iron, 2 sulfur cluster binding
FP497_RS03890	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FP497_RS03895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FP497_RS03900	COG4942	peptidase
FP497_RS03925	COG3710	Transcriptional regulator
FP497_RS03925	COG0457	Tetratricopeptide repeat
FP497_RS03930	COG0457	Tetratricopeptide repeat
FP497_RS03955	COG3710	Transcriptional regulator
FP497_RS03960	COG2771	luxR family
FP497_RS03965	COG0814	amino acid
FP497_RS03970	COG0183	Belongs to the thiolase family
FP497_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS03985	COG2814	Major facilitator Superfamily
FP497_RS03990	COG1794	racemase activity, acting on amino acids and derivatives
FP497_RS03995	COG0583	DNA-binding transcription factor activity
FP497_RS04005	COG1609	Transcriptional regulator
FP497_RS04025	COG0667	Aldo Keto reductase
FP497_RS04035	COG0861	Integral membrane protein TerC family
FP497_RS04055	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FP497_RS04070	COG2165	general secretion pathway protein
FP497_RS04075	COG4795	General secretion pathway protein
FP497_RS04085	COG4967	type IV pilus modification protein PilV
FP497_RS04090	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FP497_RS04095	COG1025	Belongs to the peptidase M16 family
FP497_RS04100	COG1074	ATP-dependent DNA helicase activity
FP497_RS04105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FP497_RS04110	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FP497_RS04110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FP497_RS04115	COG0860	N-Acetylmuramoyl-L-alanine amidase
FP497_RS04135	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FP497_RS04140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FP497_RS04145	COG2166	iron-sulfur cluster assembly
FP497_RS04150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FP497_RS04160	COG0583	DNA-binding transcription factor activity
FP497_RS04165	COG2363	Small membrane protein
FP497_RS04175	COG1349	DNA-binding transcription factor activity
FP497_RS04185	COG1070	Carbohydrate kinase
FP497_RS04195	COG0738	Major facilitator superfamily
FP497_RS04200	COG0235	Class ii aldolase
FP497_RS04205	COG1454	alcohol dehydrogenase
FP497_RS04215	COG1760	l-serine dehydratase
FP497_RS04220	COG0814	amino acid
FP497_RS04225	COG1611	Belongs to the LOG family
FP497_RS04240	COG3098	single-species biofilm formation
FP497_RS04245	COG0564	pseudouridine synthase activity
FP497_RS04250	COG0716	FMN binding
FP497_RS04255	COG2271	Major facilitator Superfamily
FP497_RS04260	COG4948	Mandelate Racemase Muconate Lactonizing
FP497_RS04265	COG4948	Mandelate Racemase Muconate Lactonizing
FP497_RS04270	COG3850	Histidine kinase
FP497_RS04270	COG4999	Histidine kinase
FP497_RS04270	COG2205	protein histidine kinase activity
FP497_RS04270	COG3437	response regulator, receiver
FP497_RS04275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FP497_RS04280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FP497_RS04285	COG2336	PFAM SpoVT AbrB
FP497_RS04290	COG2337	Toxic component of a toxin-antitoxin (TA) module
FP497_RS04295	COG3956	TIGRFAM MazG family protein
FP497_RS04310	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FP497_RS04320	COG0602	queuosine metabolic process
FP497_RS04325	COG1070	Carbohydrate kinase
FP497_RS04330	COG2223	nitrite transmembrane transporter activity
FP497_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS04340	COG0277	FAD linked oxidase domain protein
FP497_RS04345	COG0477	Major facilitator Superfamily
FP497_RS04350	COG2086	electron transfer activity
FP497_RS04355	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FP497_RS04360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FP497_RS04365	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FP497_RS04370	COG0644	oxidoreductase
FP497_RS04375	COG0720	synthase
FP497_RS04380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FP497_RS04400	COG1203	CRISPR-associated helicase, Cas3
FP497_RS04415	COG1857	crispr-associated protein
FP497_RS04430	COG1518	maintenance of DNA repeat elements
FP497_RS04435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FP497_RS04440	COG2234	aminopeptidase activity
FP497_RS04495	COG4942	peptidase
FP497_RS04495	COG1388	LysM domain
FP497_RS04500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FP497_RS04505	COG2610	gluconate transmembrane transporter activity
FP497_RS04510	COG3622	Belongs to the hyi family
FP497_RS04515	COG0235	Class ii aldolase
FP497_RS04520	COG3395	kinase activity
FP497_RS04525	COG2084	Dehydrogenase
FP497_RS04530	COG1349	DNA-binding transcription factor activity
FP497_RS04535	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FP497_RS04550	COG3604	Transcriptional regulator
FP497_RS04555	COG0309	Hydrogenase expression formation protein (HypE)
FP497_RS04560	COG0409	Hydrogenase expression formation protein
FP497_RS04565	COG0298	carbon dioxide binding
FP497_RS04570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FP497_RS04575	COG0375	protein maturation
FP497_RS04590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS04595	COG0651	ATP synthesis coupled electron transport
FP497_RS04600	COG0650	Formate hydrogenlyase subunit 4
FP497_RS04605	COG3261	NADH dehydrogenase
FP497_RS04605	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FP497_RS04610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FP497_RS04615	COG3260	NADH ubiquinone oxidoreductase 20
FP497_RS04625	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FP497_RS04630	COG2723	6-phospho-beta-galactosidase activity
FP497_RS04635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS04635	COG1263	PTS System
FP497_RS04640	COG1609	Transcriptional regulator
FP497_RS04645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS04650	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FP497_RS04670	COG0517	IMP dehydrogenase activity
FP497_RS04670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FP497_RS04675	COG1349	DNA-binding transcription factor activity
FP497_RS04680	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS04690	COG3731	PTS system glucitol sorbitol-specific IIA component
FP497_RS04695	COG3732	PTS system glucitol sorbitol-specific
FP497_RS04700	COG3730	PTS system glucitol sorbitol-specific
FP497_RS04705	COG2951	lytic endotransglycosylase activity
FP497_RS04710	COG1546	Belongs to the CinA family
FP497_RS04730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FP497_RS04760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FP497_RS04765	COG1238	metal cluster binding
FP497_RS04780	COG2814	Major facilitator Superfamily
FP497_RS04785	COG1566	PFAM secretion protein HlyD family protein
FP497_RS04790	COG1846	Transcriptional regulator
FP497_RS04800	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FP497_RS04810	COG2113	Glycine betaine
FP497_RS04815	COG4176	ABC-type proline glycine betaine transport system permease component
FP497_RS04820	COG4175	Glycine betaine
FP497_RS04825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FP497_RS04830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FP497_RS04840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FP497_RS04845	COG4575	ribosome binding
FP497_RS04860	COG2916	Histone family protein nucleoid-structuring protein H-NS
FP497_RS04865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FP497_RS04870	COG0640	Transcriptional regulator
FP497_RS04875	COG0401	homolog of Blt101
FP497_RS04880	COG1652	LysM domain
FP497_RS04885	COG1802	Transcriptional regulator
FP497_RS04890	COG1113	amino acid transport
FP497_RS04895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FP497_RS04900	COG1012	belongs to the aldehyde dehydrogenase family
FP497_RS04915	COG2867	negative regulation of translational initiation
FP497_RS04925	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FP497_RS04930	COG0497	DNA recombination
FP497_RS04945	COG4536	flavin adenine dinucleotide binding
FP497_RS04950	COG4137	Cytochrome C assembly protein
FP497_RS04955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FP497_RS04980	COG2885	chlorophyll binding
FP497_RS04985	COG2199	diguanylate cyclase activity
FP497_RS05000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FP497_RS05005	COG1605	Chorismate mutase
FP497_RS05005	COG0287	Prephenate dehydrogenase
FP497_RS05010	COG0077	Prephenate dehydratase
FP497_RS05010	COG1605	Chorismate mutase
FP497_RS05020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FP497_RS05025	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FP497_RS05030	COG0564	pseudouridine synthase activity
FP497_RS05035	COG1496	oxidoreductase activity
FP497_RS05040	COG0542	response to heat
FP497_RS05065	COG0477	Major facilitator Superfamily
FP497_RS05070	COG5544	Lipoprotein
FP497_RS05075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FP497_RS05080	COG0045	succinate-CoA ligase (ADP-forming) activity
FP497_RS05080	COG1042	CoA-binding domain protein
FP497_RS05080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FP497_RS05085	COG3148	PFAM DTW domain containing protein
FP497_RS05090	COG3118	belongs to the thioredoxin family
FP497_RS05095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FP497_RS05115	COG0583	DNA-binding transcription factor activity
FP497_RS05120	COG0513	Belongs to the DEAD box helicase family
FP497_RS05130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FP497_RS05140	COG1595	DNA-templated transcription, initiation
FP497_RS05145	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FP497_RS05150	COG3026	antisigma factor binding
FP497_RS05155	COG3086	response to oxidative stress
FP497_RS05165	COG0681	Belongs to the peptidase S26 family
FP497_RS05185	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FP497_RS05200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS05205	COG1737	Transcriptional regulator
FP497_RS05210	COG0560	Phosphoserine phosphatase
FP497_RS05225	COG0047	phosphoribosylformylglycinamidine synthase activity
FP497_RS05225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FP497_RS05230	COG2205	protein histidine kinase activity
FP497_RS05235	COG3170	Tfp pilus assembly protein FimV
FP497_RS05240	COG2204	response regulator
FP497_RS05245	COG0347	Belongs to the P(II) protein family
FP497_RS05250	COG1017	nitric oxide dioxygenase activity
FP497_RS05250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FP497_RS05260	COG1940	carbohydrate kinase activity
FP497_RS05265	COG0457	Tetratricopeptide repeat
FP497_RS05270	COG1879	ABC-type sugar transport system periplasmic component
FP497_RS05275	COG1129	ABC transporter
FP497_RS05280	COG1172	Belongs to the binding-protein-dependent transport system permease family
FP497_RS05285	COG1063	alcohol dehydrogenase
FP497_RS05290	COG2017	converts alpha-aldose to the beta-anomer
FP497_RS05295	COG2259	Doxx family
FP497_RS05320	COG4638	Rieske (2fe-2S)
FP497_RS05325	COG0583	DNA-binding transcription factor activity
FP497_RS05330	COG2814	Major facilitator Superfamily
FP497_RS05335	COG3711	transcriptional antiterminator
FP497_RS05340	COG1073	alpha beta
FP497_RS05345	COG0483	inositol monophosphate 1-phosphatase activity
FP497_RS05365	COG0822	iron-sulfur transferase activity
FP497_RS05385	COG0633	Ferredoxin
FP497_RS05390	COG2975	iron-sulfur cluster assembly
FP497_RS05405	COG2897	thiosulfate sulfurtransferase activity
FP497_RS05410	COG2373	Large extracellular alpha-helical protein
FP497_RS05415	COG4953	penicillin-binding protein 1C
FP497_RS05445	COG2976	Protein conserved in bacteria
FP497_RS05450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FP497_RS05460	COG1645	bacterial-type flagellum-dependent swarming motility
FP497_RS05470	COG0517	IMP dehydrogenase activity
FP497_RS05470	COG0516	GMP reductase activity
FP497_RS05485	COG3133	Outer membrane lipoprotein
FP497_RS05495	COG2200	EAL domain
FP497_RS05500	COG0248	Ppx GppA phosphatase
FP497_RS05505	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FP497_RS05510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FP497_RS05525	COG2233	PERMEase
FP497_RS05535	COG1393	Belongs to the ArsC family
FP497_RS05540	COG4783	chaperone-mediated protein folding
FP497_RS05545	COG0628	permease
FP497_RS05550	COG2116	formate transmembrane transporter activity
FP497_RS05555	COG3604	Transcriptional regulator
FP497_RS05565	COG3260	NADH ubiquinone oxidoreductase 20
FP497_RS05570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FP497_RS05575	COG3261	NADH dehydrogenase
FP497_RS05575	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FP497_RS05580	COG0651	ATP synthesis coupled electron transport
FP497_RS05585	COG4237	Hydrogenase 4 membrane
FP497_RS05590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FP497_RS05595	COG0650	Formate hydrogenlyase subunit 4
FP497_RS05600	COG0651	ATP synthesis coupled electron transport
FP497_RS05605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS05610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FP497_RS05615	COG2716	regulation of RNA biosynthetic process
FP497_RS05625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FP497_RS05635	COG2321	neutral zinc metallopeptidase
FP497_RS05640	COG1444	tRNA N-acetyltransferase activity
FP497_RS05645	COG0400	carboxylic ester hydrolase activity
FP497_RS05660	COG1393	Belongs to the ArsC family
FP497_RS05670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FP497_RS05675	COG3850	Histidine kinase
FP497_RS05680	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS05680	COG0493	'glutamate synthase
FP497_RS05690	COG5342	invasion associated locus B
FP497_RS05695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FP497_RS05700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FP497_RS05705	COG0281	malic enzyme
FP497_RS05705	COG0280	phosphate acetyltransferase
FP497_RS05710	COG4810	utilization protein
FP497_RS05715	COG4917	ethanolamine utilization protein
FP497_RS05720	COG4766	ethanolamine catabolic process
FP497_RS05725	COG4812	Cobalamin adenosyltransferase
FP497_RS05730	COG0280	phosphate acetyltransferase
FP497_RS05735	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FP497_RS05740	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FP497_RS05745	COG1012	belongs to the aldehyde dehydrogenase family
FP497_RS05750	COG4820	ethanolamine utilization protein (EutJ)
FP497_RS05755	COG1454	alcohol dehydrogenase
FP497_RS05760	COG3192	ethanolamine utilization protein
FP497_RS05765	COG4819	ethanolamine utilization protein
FP497_RS05770	COG4303	Ethanolamine ammonia lyase large subunit
FP497_RS05780	COG4816	utilization protein
FP497_RS05785	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FP497_RS05790	COG2207	Transcriptional regulator
FP497_RS05800	COG0860	N-Acetylmuramoyl-L-alanine amidase
FP497_RS05805	COG0456	acetyltransferase
FP497_RS05820	COG2837	iron assimilation
FP497_RS05825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FP497_RS05830	COG1263	PTS System
FP497_RS05830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS05850	COG4150	thiosulfate binding
FP497_RS05855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FP497_RS05860	COG4208	sulfate ABC transporter
FP497_RS05865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FP497_RS05870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FP497_RS05875	COG3831	ATPase activity
FP497_RS05875	COG4884	unkown
FP497_RS05890	COG2190	(PTS) system
FP497_RS05895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FP497_RS05900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS05905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FP497_RS05925	COG3530	Putative quorum-sensing-regulated virulence factor
FP497_RS05930	COG0385	Bile acid
FP497_RS05935	COG0583	DNA-binding transcription factor activity
FP497_RS05945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FP497_RS05950	COG2211	Major facilitator Superfamily
FP497_RS05960	COG0583	DNA-binding transcription factor activity
FP497_RS05995	COG3415	Transposase
FP497_RS06000	COG3415	Transposase
FP497_RS06020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS06025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS06030	COG0006	proline dipeptidase activity
FP497_RS06035	COG1363	Peptidase, m42
FP497_RS06040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FP497_RS06040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS06040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS06045	COG2207	Transcriptional regulator
FP497_RS06050	COG3279	Response regulator of the LytR AlgR family
FP497_RS06055	COG3275	phosphorelay sensor kinase activity
FP497_RS06060	COG0436	Aminotransferase
FP497_RS06070	COG1560	Kdo2-lipid A biosynthetic process
FP497_RS06095	COG0028	Belongs to the TPP enzyme family
FP497_RS06100	COG0679	Auxin Efflux Carrier
FP497_RS06105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FP497_RS06110	COG2205	protein histidine kinase activity
FP497_RS06110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FP497_RS06110	COG0784	Response regulator, receiver
FP497_RS06110	COG2198	Histidine kinase
FP497_RS06115	COG2197	response regulator
FP497_RS06120	COG1566	PFAM secretion protein HlyD family protein
FP497_RS06125	COG0477	Major facilitator Superfamily
FP497_RS06135	COG2610	gluconate transmembrane transporter activity
FP497_RS06140	COG0583	DNA-binding transcription factor activity
FP497_RS06155	COG2116	formate transmembrane transporter activity
FP497_RS06160	COG2853	Lipoprotein
FP497_RS06170	COG2067	long-chain fatty acid transport protein
FP497_RS06175	COG3691	Protein conserved in bacteria
FP497_RS06190	COG2062	phosphohistidine phosphatase, SixA
FP497_RS06195	COG3539	Fimbrial protein
FP497_RS06205	COG3121	Chaperone
FP497_RS06210	COG3539	Fimbrial protein
FP497_RS06215	COG3539	Fimbrial protein
FP497_RS06220	COG3539	Fimbrial protein
FP497_RS06235	COG2890	protein-(glutamine-N5) methyltransferase activity
FP497_RS06250	COG0730	response to heat
FP497_RS06255	COG3101	peptidyl-lysine hydroxylation
FP497_RS06270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FP497_RS06275	COG2814	Major facilitator Superfamily
FP497_RS06290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FP497_RS06300	COG0586	Pfam SNARE associated Golgi protein
FP497_RS06310	COG0285	dihydrofolate synthase activity
FP497_RS06315	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FP497_RS06320	COG1286	toxin biosynthetic process
FP497_RS06325	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FP497_RS06330	COG0163	prenyltransferase activity
FP497_RS06335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FP497_RS06340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FP497_RS06345	COG4215	(ABC) transporter
FP497_RS06350	COG4160	amino acid transport
FP497_RS06355	COG4598	ABC transporter
FP497_RS06360	COG5464	transposase or invertase
FP497_RS06365	COG1090	epimerase
FP497_RS06370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FP497_RS06375	COG0625	glutathione transferase activity
FP497_RS06380	COG0625	glutathione transferase activity
FP497_RS06385	COG0622	Phosphoesterase
FP497_RS06390	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FP497_RS06395	COG1288	antiporter activity
FP497_RS06400	COG0280	phosphate acetyltransferase
FP497_RS06400	COG0857	belongs to the CobB CobQ family
FP497_RS06405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FP497_RS06420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FP497_RS06425	COG0490	domain, Protein
FP497_RS06425	COG0471	metal ion transport
FP497_RS06435	COG0436	Aminotransferase
FP497_RS06440	COG0583	DNA-binding transcription factor activity
FP497_RS06460	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FP497_RS06465	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FP497_RS06470	COG1034	ATP synthesis coupled electron transport
FP497_RS06485	COG0839	Belongs to the complex I subunit 6 family
FP497_RS06495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FP497_RS06500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FP497_RS06510	COG0457	Tetratricopeptide repeat
FP497_RS06530	COG2234	aminopeptidase activity
FP497_RS06535	COG2304	oxidoreductase activity
FP497_RS06540	COG5160	protein modification by small protein removal
FP497_RS06550	COG2153	protein acetylation
FP497_RS06555	COG4575	ribosome binding
FP497_RS06560	COG1169	isochorismate synthase
FP497_RS06575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FP497_RS06585	COG0318	PFAM AMP-dependent synthetase and ligase
FP497_RS06650	COG1414	Transcriptional regulator
FP497_RS06660	COG2271	Major facilitator Superfamily
FP497_RS06675	COG5464	transposase or invertase
FP497_RS06680	COG0247	lactate metabolic process
FP497_RS06690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FP497_RS06695	COG2271	Major facilitator Superfamily
FP497_RS06700	COG0584	glycerophosphoryl diester phosphodiesterase
FP497_RS06710	COG3642	lipopolysaccharide core region biosynthetic process
FP497_RS06715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FP497_RS06720	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FP497_RS06725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FP497_RS06730	COG3468	outer membrane autotransporter barrel domain protein
FP497_RS06740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FP497_RS06745	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
FP497_RS06750	COG3234	Protein of unknown function (DUF1175)
FP497_RS06760	COG5445	Predicted secreted protein (DUF2300)
FP497_RS06765	COG4676	Protein conserved in bacteria
FP497_RS06770	COG0183	Belongs to the thiolase family
FP497_RS06775	COG2031	fatty acid transporter
FP497_RS06780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FP497_RS06785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FP497_RS06790	COG2204	response regulator
FP497_RS06795	COG3852	Histidine kinase
FP497_RS06800	COG0784	Response regulator, receiver
FP497_RS06800	COG2205	protein histidine kinase activity
FP497_RS06805	COG2197	response regulator
FP497_RS06810	COG0642	Histidine kinase
FP497_RS06810	COG2198	Histidine kinase
FP497_RS06815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FP497_RS06820	COG1477	protein flavinylation
FP497_RS06825	COG2169	Transcriptional regulator
FP497_RS06825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FP497_RS06830	COG3145	DNA-N1-methyladenine dioxygenase activity
FP497_RS06835	COG4615	Cyclic peptide transporter
FP497_RS06850	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS06850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FP497_RS06855	COG3062	negative regulation of establishment of protein localization
FP497_RS06865	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS06870	COG0348	domain, Protein
FP497_RS06875	COG3043	anaerobic respiration
FP497_RS06880	COG3005	denitrification pathway
FP497_RS06885	COG4133	protoheme IX ABC transporter activity
FP497_RS06890	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FP497_RS06895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FP497_RS06900	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FP497_RS06910	COG1138	Cytochrome C-type biogenesis protein
FP497_RS06915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FP497_RS06920	COG3088	subunit of a heme lyase
FP497_RS06920	COG4235	cytochrome complex assembly
FP497_RS06925	COG2197	response regulator
FP497_RS06935	COG3083	sulfuric ester hydrolase activity
FP497_RS06955	COG1061	Type III restriction enzyme res subunit
FP497_RS06960	COG1187	pseudouridine synthase activity
FP497_RS06965	COG2814	Major facilitator Superfamily
FP497_RS06975	COG4172	Belongs to the ABC transporter superfamily
FP497_RS06980	COG4239	(ABC) transporter, permease
FP497_RS06985	COG4174	ABC transporter (Permease)
FP497_RS06990	COG4166	transmembrane transport
FP497_RS06995	COG2200	EAL domain
FP497_RS07000	COG0791	NLP P60 protein
FP497_RS07005	COG0671	phosphoesterase, PA-phosphatase related
FP497_RS07010	COG0523	cobalamin synthesis protein
FP497_RS07015	COG0246	Mannitol dehydrogenase
FP497_RS07030	COG2814	Major facilitator Superfamily
FP497_RS07035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS07035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS07040	COG1105	Belongs to the carbohydrate kinase PfkB family
FP497_RS07045	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FP497_RS07045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS07045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS07050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS07055	COG2313	pseudouridylate synthase activity
FP497_RS07060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FP497_RS07065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FP497_RS07075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FP497_RS07080	COG1522	sequence-specific DNA binding
FP497_RS07080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS07090	COG2855	membrane
FP497_RS07095	COG0583	DNA-binding transcription factor activity
FP497_RS07100	COG0833	amino acid
FP497_RS07105	COG4771	TonB-dependent receptor
FP497_RS07120	COG2311	Membrane
FP497_RS07125	COG1609	Transcriptional regulator
FP497_RS07130	COG1879	ABC-type sugar transport system periplasmic component
FP497_RS07135	COG1129	ABC transporter
FP497_RS07140	COG4211	Belongs to the binding-protein-dependent transport system permease family
FP497_RS07145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FP497_RS07145	COG0167	dihydroorotate dehydrogenase activity
FP497_RS07150	COG0493	'glutamate synthase
FP497_RS07160	COG2949	membrane
FP497_RS07170	COG1346	cytolysis
FP497_RS07180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FP497_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS07200	COG0586	Pfam SNARE associated Golgi protein
FP497_RS07210	COG1686	Belongs to the peptidase S11 family
FP497_RS07215	COG0277	FAD linked oxidase domain protein
FP497_RS07220	COG1472	Belongs to the glycosyl hydrolase 3 family
FP497_RS07225	COG1732	Glycine betaine
FP497_RS07230	COG1174	glycine betaine transport
FP497_RS07235	COG1125	glycine betaine transport
FP497_RS07240	COG1174	glycine betaine transport
FP497_RS07250	COG0789	Transcriptional regulator
FP497_RS07255	COG3275	phosphorelay sensor kinase activity
FP497_RS07260	COG3279	Response regulator of the LytR AlgR family
FP497_RS07265	COG4807	Protein conserved in bacteria
FP497_RS07270	COG4808	Protein conserved in bacteria
FP497_RS07280	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FP497_RS07285	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FP497_RS07290	COG0714	Associated with various cellular activities
FP497_RS07300	COG3831	ATPase activity
FP497_RS07315	COG0489	protein tyrosine kinase activity
FP497_RS07325	COG3539	Fimbrial protein
FP497_RS07330	COG3121	Chaperone
FP497_RS07335	COG3188	usher protein
FP497_RS07340	COG3539	Fimbrial protein
FP497_RS07345	COG5455	response to cobalt ion
FP497_RS07350	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FP497_RS07365	COG0351	phosphomethylpyrimidine kinase
FP497_RS07370	COG3757	hydrolase, family 25
FP497_RS07375	COG2188	Transcriptional regulator
FP497_RS07380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS07385	COG1397	ADP-ribosylglycohydrolase
FP497_RS07390	COG2211	Major facilitator Superfamily
FP497_RS07395	COG1830	Aldolase
FP497_RS07400	COG0745	RESPONSE REGULATOR receiver
FP497_RS07405	COG2205	protein histidine kinase activity
FP497_RS07440	COG4245	von Willebrand factor, type A
FP497_RS07445	COG0631	protein serine/threonine phosphatase activity
FP497_RS07450	COG3779	Protein conserved in bacteria
FP497_RS07455	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
FP497_RS07460	COG0443	Heat shock 70 kDa protein
FP497_RS07465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FP497_RS07470	COG3447	MASE1 domain protein
FP497_RS07470	COG5001	Diguanylate cyclase
FP497_RS07470	COG5002	protein histidine kinase activity
FP497_RS07475	COG0572	uridine kinase
FP497_RS07485	COG2982	Protein involved in outer membrane biogenesis
FP497_RS07490	COG1253	flavin adenine dinucleotide binding
FP497_RS07495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FP497_RS07500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FP497_RS07505	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FP497_RS07510	COG0140	phosphoribosyl-ATP diphosphatase activity
FP497_RS07510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FP497_RS07525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FP497_RS07530	COG0131	Imidazoleglycerol-phosphate dehydratase
FP497_RS07530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FP497_RS07540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FP497_RS07555	COG2161	toxin-antitoxin pair type II binding
FP497_RS07560	COG4115	mRNA cleavage
FP497_RS07565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FP497_RS07570	COG0583	DNA-binding transcription factor activity
FP497_RS07580	COG0531	amino acid
FP497_RS07585	COG2391	methyltransferase activity
FP497_RS07590	COG0425	Belongs to the sulfur carrier protein TusA family
FP497_RS07595	COG2925	Exonuclease
FP497_RS07600	COG1686	Belongs to the peptidase S11 family
FP497_RS07615	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FP497_RS07630	COG1376	ErfK ybiS ycfS ynhG family protein
FP497_RS07640	COG0583	DNA-binding transcription factor activity
FP497_RS07645	COG0583	DNA-binding transcription factor activity
FP497_RS07655	COG0534	Mate efflux family protein
FP497_RS07665	COG0217	transcriptional regulatory protein
FP497_RS07670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FP497_RS07675	COG0477	Major facilitator Superfamily
FP497_RS07685	COG1388	LysM domain
FP497_RS07685	COG1470	cell adhesion involved in biofilm formation
FP497_RS07705	COG3038	cytochrome b561
FP497_RS07710	COG3443	Belongs to the bacterial solute-binding protein 9 family
FP497_RS07720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FP497_RS07725	COG2351	hydroxyisourate hydrolase activity
FP497_RS07730	COG0745	RESPONSE REGULATOR receiver
FP497_RS07735	COG2205	protein histidine kinase activity
FP497_RS07760	COG1418	mRNA catabolic process
FP497_RS07765	COG0270	DNA (cytosine-5-)-methyltransferase activity
FP497_RS07770	COG3727	T/G mismatch-specific endonuclease activity
FP497_RS07775	COG0697	spore germination
FP497_RS07780	COG2354	Protein conserved in bacteria
FP497_RS07785	COG5475	Uncharacterized small protein (DUF2158)
FP497_RS07790	COG3706	GGDEF domain
FP497_RS07815	COG2197	response regulator
FP497_RS07825	COG2197	response regulator
FP497_RS07840	COG2197	response regulator
FP497_RS07870	COG3012	SEC-C Motif Domain Protein
FP497_RS07870	COG3318	Belongs to the UPF0149 family
FP497_RS07875	COG0814	amino acid
FP497_RS07885	COG1528	Iron-storage protein
FP497_RS07905	COG1528	Iron-storage protein
FP497_RS07910	COG1879	ABC-type sugar transport system periplasmic component
FP497_RS07915	COG1129	ABC transporter
FP497_RS07920	COG1172	Belongs to the binding-protein-dependent transport system permease family
FP497_RS07925	COG1877	trehalose-phosphatase activity
FP497_RS07935	COG0589	response to stress
FP497_RS07940	COG3755	Protein conserved in bacteria
FP497_RS07950	COG3102	Protein conserved in bacteria
FP497_RS07960	COG3005	denitrification pathway
FP497_RS07965	COG0243	molybdopterin cofactor binding
FP497_RS07980	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FP497_RS07985	COG1801	Protein of unknown function DUF72
FP497_RS07990	COG1335	isochorismatase
FP497_RS08000	COG0494	nUDIX hydrolase
FP497_RS08005	COG0217	transcriptional regulatory protein
FP497_RS08035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FP497_RS08045	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FP497_RS08050	COG0739	heme binding
FP497_RS08055	COG1560	Kdo2-lipid A biosynthetic process
FP497_RS08060	COG0469	pyruvate kinase activity
FP497_RS08065	COG1737	Transcriptional regulator
FP497_RS08070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FP497_RS08075	COG0129	dihydroxy-acid dehydratase activity
FP497_RS08080	COG0800	Aldolase
FP497_RS08090	COG3141	response to X-ray
FP497_RS08100	COG2979	Protein of unknown function (DUF533)
FP497_RS08105	COG1770	oligopeptidase
FP497_RS08110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FP497_RS08115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FP497_RS08125	COG2372	response to copper ion
FP497_RS08130	COG1276	copper resistance
FP497_RS08140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FP497_RS08160	COG3008	intermembrane lipid transfer
FP497_RS08165	COG2995	paraquat-inducible protein a
FP497_RS08170	COG1956	GAF domain-containing protein
FP497_RS08180	COG0793	Belongs to the peptidase S41A family
FP497_RS08190	COG2814	Major facilitator Superfamily
FP497_RS08195	COG1414	Transcriptional regulator
FP497_RS08225	COG2226	methyltransferase
FP497_RS08240	COG3716	PTS system mannose fructose sorbose family IID component
FP497_RS08245	COG3715	PTS system
FP497_RS08250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS08250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS08255	COG1253	flavin adenine dinucleotide binding
FP497_RS08260	COG2200	EAL domain
FP497_RS08265	COG1760	l-serine dehydratase
FP497_RS08275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FP497_RS08290	COG0251	oxidation-reduction process
FP497_RS08295	COG1199	ATP-dependent helicase activity
FP497_RS08300	COG1214	PFAM Peptidase M22, glycoprotease
FP497_RS08305	COG3065	identical protein binding
FP497_RS08310	COG0318	PFAM AMP-dependent synthetase and ligase
FP497_RS08315	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FP497_RS08320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FP497_RS08325	COG4638	Rieske (2fe-2S)
FP497_RS08330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FP497_RS08335	COG0473	3-isopropylmalate dehydrogenase activity
FP497_RS08340	COG0583	DNA-binding transcription factor activity
FP497_RS08350	COG3615	Tellurite resistance protein tehB
FP497_RS08360	COG2261	transglycosylase associated protein
FP497_RS08375	COG2199	diguanylate cyclase activity
FP497_RS08375	COG2203	Gaf domain
FP497_RS08380	COG3042	response to heat
FP497_RS08385	COG3189	MarR family transcriptional regulator
FP497_RS08390	COG2807	transmembrane transport
FP497_RS08395	COG2207	Transcriptional regulator
FP497_RS08410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FP497_RS08425	COG2199	diguanylate cyclase activity
FP497_RS08435	COG2766	serine protein kinase
FP497_RS08440	COG3713	MltA-interacting MipA family protein
FP497_RS08445	COG0656	L-ascorbic acid biosynthetic process
FP497_RS08450	COG0676	glucose-6-phosphate 1-epimerase activity
FP497_RS08455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FP497_RS08465	COG3139	Protein of unknown function (DUF1315)
FP497_RS08470	COG1063	alcohol dehydrogenase
FP497_RS08475	COG2271	Major facilitator Superfamily
FP497_RS08480	COG1063	alcohol dehydrogenase
FP497_RS08485	COG0191	fructose-bisphosphate aldolase activity
FP497_RS08490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS08495	COG0667	Aldo Keto reductase
FP497_RS08500	COG1349	DNA-binding transcription factor activity
FP497_RS08505	COG2814	Major facilitator Superfamily
FP497_RS08510	COG1335	isochorismatase
FP497_RS08515	COG0252	asparaginase activity
FP497_RS08520	COG0616	signal peptide processing
FP497_RS08525	COG0778	Nitroreductase
FP497_RS08535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FP497_RS08545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FP497_RS08555	COG0494	nUDIX hydrolase
FP497_RS08560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FP497_RS08565	COG2897	thiosulfate sulfurtransferase activity
FP497_RS08570	COG4136	ATPase activity
FP497_RS08575	COG4135	transport system, permease component
FP497_RS08580	COG4134	Bacterial extracellular solute-binding protein
FP497_RS08585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FP497_RS08590	COG0398	Pfam SNARE associated Golgi protein
FP497_RS08600	COG0398	Pfam SNARE associated Golgi protein
FP497_RS08605	COG0708	Exodeoxyribonuclease III
FP497_RS08635	COG3678	ATP-independent chaperone mediated protein folding
FP497_RS08645	COG0322	excinuclease ABC activity
FP497_RS08655	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FP497_RS08660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FP497_RS08665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FP497_RS08670	COG1447	Phosphotransferase system cellobiose-specific component IIA
FP497_RS08675	COG2169	Transcriptional regulator
FP497_RS08675	COG1917	Cupin 2, conserved barrel domain protein
FP497_RS08680	COG1486	melibiose metabolic process
FP497_RS08690	COG0753	catalase activity
FP497_RS08705	COG1823	symporter activity
FP497_RS08710	COG1988	membrane-bound metal-dependent
FP497_RS08715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FP497_RS08725	COG3001	Fructosamine kinase
FP497_RS08735	COG1105	Belongs to the carbohydrate kinase PfkB family
FP497_RS08740	COG3137	Salt-induced outer membrane protein
FP497_RS08785	COG0072	phenylalanine-tRNA ligase activity
FP497_RS08785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FP497_RS08800	COG0386	Belongs to the glutathione peroxidase family
FP497_RS08810	COG0791	NLP P60 protein
FP497_RS08815	COG2200	EAL domain
FP497_RS08825	COG4256	Hemin uptake protein
FP497_RS08830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FP497_RS08840	COG0574	Belongs to the PEP-utilizing enzyme family
FP497_RS08840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FP497_RS08845	COG0318	PFAM AMP-dependent synthetase and ligase
FP497_RS08850	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FP497_RS08855	COG0644	oxidoreductase
FP497_RS08860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FP497_RS08865	COG2086	electron transfer activity
FP497_RS08870	COG1917	Cupin 2, conserved barrel domain protein
FP497_RS08870	COG2207	Transcriptional regulator
FP497_RS08875	COG1960	acyl-CoA dehydrogenase activity
FP497_RS08880	COG4670	ketone body catabolic process
FP497_RS08895	COG2271	Major facilitator Superfamily
FP497_RS08900	COG0738	Major facilitator superfamily
FP497_RS08915	COG0628	permease
FP497_RS08920	COG0247	lactate metabolic process
FP497_RS08920	COG0277	FAD linked oxidase domain protein
FP497_RS08925	COG2050	protein possibly involved in aromatic compounds catabolism
FP497_RS08935	COG0316	Belongs to the HesB IscA family
FP497_RS08940	COG0719	Fe-S assembly protein
FP497_RS08945	COG0396	ATPase activity
FP497_RS08950	COG0719	Fe-S assembly protein
FP497_RS08965	COG1376	ErfK ybiS ycfS ynhG family protein
FP497_RS08970	COG4238	major outer membrane lipoprotein
FP497_RS08975	COG0469	pyruvate kinase activity
FP497_RS08985	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS08990	COG2414	aldehyde ferredoxin oxidoreductase
FP497_RS09000	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS09005	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FP497_RS09015	COG4529	Protein conserved in bacteria
FP497_RS09035	COG3468	outer membrane autotransporter barrel domain protein
FP497_RS09045	COG0307	riboflavin synthase, alpha
FP497_RS09050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FP497_RS09055	COG2814	Major facilitator Superfamily
FP497_RS09060	COG0583	DNA-binding transcription factor activity
FP497_RS09075	COG2814	Major facilitator Superfamily
FP497_RS09080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FP497_RS09085	COG0791	NLP P60 protein
FP497_RS09090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FP497_RS09095	COG1201	RNA secondary structure unwinding
FP497_RS09100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FP497_RS09105	COG0346	lactoylglutathione lyase activity
FP497_RS09110	COG1902	pentaerythritol trinitrate reductase activity
FP497_RS09115	COG1309	transcriptional regulator
FP497_RS09120	COG3313	Fe-S protein
FP497_RS09125	COG4989	oxidoreductase activity
FP497_RS09130	COG2032	superoxide dismutase activity
FP497_RS09135	COG1289	transmembrane transporter activity
FP497_RS09140	COG1566	PFAM secretion protein HlyD family protein
FP497_RS09155	COG3133	Outer membrane lipoprotein
FP497_RS09165	COG3895	Periplasmic Protein
FP497_RS09180	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FP497_RS09185	COG0625	glutathione transferase activity
FP497_RS09190	COG3104	oligopeptide transport
FP497_RS09195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FP497_RS09205	COG4659	FMN binding
FP497_RS09245	COG0673	inositol 2-dehydrogenase activity
FP497_RS09255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FP497_RS09260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS09260	COG1263	PTS System
FP497_RS09265	COG1609	Transcriptional regulator
FP497_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS09275	COG1309	transcriptional regulator
FP497_RS09280	COG3250	beta-galactosidase activity
FP497_RS09285	COG2211	Major facilitator Superfamily
FP497_RS09295	COG5339	Protein conserved in bacteria
FP497_RS09300	COG1482	cell wall glycoprotein biosynthetic process
FP497_RS09305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FP497_RS09305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FP497_RS09310	COG0114	fumarate hydratase activity
FP497_RS09320	COG2205	protein histidine kinase activity
FP497_RS09325	COG0745	RESPONSE REGULATOR receiver
FP497_RS09330	COG3136	membrane protein required for alginate biosynthesis
FP497_RS09340	COG0531	amino acid
FP497_RS09350	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FP497_RS09355	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FP497_RS09360	COG0628	permease
FP497_RS09380	COG3591	Belongs to the peptidase S1B family
FP497_RS09395	COG2814	Major facilitator Superfamily
FP497_RS09400	COG0583	DNA-binding transcription factor activity
FP497_RS09405	COG1940	carbohydrate kinase activity
FP497_RS09410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FP497_RS09420	COG3381	protein complex oligomerization
FP497_RS09425	COG3302	dmso reductase anchor subunit
FP497_RS09430	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS09435	COG0243	molybdopterin cofactor binding
FP497_RS09440	COG0243	molybdopterin cofactor binding
FP497_RS09455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FP497_RS09470	COG4948	Mandelate Racemase Muconate Lactonizing
FP497_RS09475	COG1063	alcohol dehydrogenase
FP497_RS09480	COG0339	signal peptide processing
FP497_RS09485	COG1546	Belongs to the CinA family
FP497_RS09490	COG3111	PFAM Bacterial OB fold (BOF) protein
FP497_RS09495	COG3706	GGDEF domain
FP497_RS09505	COG2814	Major facilitator Superfamily
FP497_RS09510	COG0697	spore germination
FP497_RS09520	COG4977	sequence-specific DNA binding
FP497_RS09525	COG1846	Transcriptional regulator
FP497_RS09545	COG0583	DNA-binding transcription factor activity
FP497_RS09550	COG1012	belongs to the aldehyde dehydrogenase family
FP497_RS09555	COG2066	Belongs to the glutaminase family
FP497_RS09565	COG2199	diguanylate cyclase activity
FP497_RS09575	COG3781	membrane
FP497_RS09635	COG1396	sequence-specific DNA binding
FP497_RS09640	COG3550	peptidyl-serine autophosphorylation
FP497_RS09655	COG3539	Fimbrial protein
FP497_RS09660	COG3539	Fimbrial protein
FP497_RS09665	COG3539	Fimbrial protein
FP497_RS09670	COG0243	molybdopterin cofactor binding
FP497_RS09680	COG2207	Transcriptional regulator
FP497_RS09685	COG3119	arylsulfatase activity
FP497_RS09690	COG0641	radical SAM
FP497_RS09700	COG4178	(ABC) transporter
FP497_RS09705	COG4771	TonB-dependent receptor
FP497_RS09710	COG0612	Peptidase, M16
FP497_RS09715	COG0076	glutamate decarboxylase activity
FP497_RS09720	COG0531	amino acid
FP497_RS09725	COG1649	PFAM Uncharacterised BCR, COG1649
FP497_RS09730	COG3706	GGDEF domain
FP497_RS09735	COG2200	EAL domain
FP497_RS09735	COG2199	diguanylate cyclase activity
FP497_RS09735	COG2202	Pas domain
FP497_RS09740	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FP497_RS09745	COG0747	negative chemotaxis
FP497_RS09750	COG0601	transmembrane transport
FP497_RS09755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FP497_RS09760	COG0444	Belongs to the ABC transporter superfamily
FP497_RS09765	COG4608	Belongs to the ABC transporter superfamily
FP497_RS09770	COG1764	response to oxidative stress
FP497_RS09790	COG1064	alcohol dehydrogenase
FP497_RS09795	COG3093	addiction module antidote protein HigA
FP497_RS09800	COG2864	formate dehydrogenase
FP497_RS09805	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS09815	COG0697	spore germination
FP497_RS09820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FP497_RS09830	COG2223	nitrite transmembrane transporter activity
FP497_RS09835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FP497_RS09840	COG1140	nitrate reductase beta subunit
FP497_RS09845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FP497_RS09850	COG2181	nitrate reductase activity
FP497_RS09855	COG0384	phenazine biosynthesis protein PhzF
FP497_RS09860	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FP497_RS09875	COG0625	glutathione transferase activity
FP497_RS09880	COG1113	amino acid transport
FP497_RS09885	COG3391	amine dehydrogenase activity
FP497_RS09890	COG4772	TonB-dependent receptor
FP497_RS09895	COG1802	Transcriptional regulator
FP497_RS09900	COG2130	NADP-dependent
FP497_RS09905	COG1247	-acetyltransferase
FP497_RS09910	COG3238	Protein conserved in bacteria
FP497_RS09935	COG1177	transmembrane transport
FP497_RS09940	COG1176	ABC-type spermidine putrescine transport system, permease component I
FP497_RS09945	COG3842	ATPase activity
FP497_RS09950	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FP497_RS09955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FP497_RS09960	COG1598	PFAM Uncharacterised protein family UPF0150
FP497_RS09965	COG1724	mRNA binding
FP497_RS09975	COG0826	peptidase U32
FP497_RS09980	COG1396	sequence-specific DNA binding
FP497_RS09985	COG3135	benzoate transporter
FP497_RS09990	COG0675	Transposase, IS605 OrfB family
FP497_RS10005	COG0500	methyltransferase
FP497_RS10010	COG1275	C4-dicarboxylate transporter malic acid transport protein
FP497_RS10015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FP497_RS10020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FP497_RS10025	COG2841	Protein conserved in bacteria
FP497_RS10035	COG5383	Protein conserved in bacteria
FP497_RS10040	COG0583	DNA-binding transcription factor activity
FP497_RS10045	COG0840	transmembrane signaling receptor activity
FP497_RS10060	COG3038	cytochrome b561
FP497_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
FP497_RS10075	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FP497_RS10080	COG1643	Atp-dependent helicase
FP497_RS10090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FP497_RS10095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FP497_RS10100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FP497_RS10105	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FP497_RS10115	COG3106	COG3106 Predicted ATPase
FP497_RS10120	COG1609	Transcriptional regulator
FP497_RS10135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FP497_RS10140	COG1554	hydrolase, family 65, central catalytic
FP497_RS10145	COG0673	inositol 2-dehydrogenase activity
FP497_RS10150	COG1082	Xylose isomerase domain protein TIM barrel
FP497_RS10155	COG1063	alcohol dehydrogenase
FP497_RS10160	COG0395	ABC-type sugar transport system, permease component
FP497_RS10165	COG1175	transmembrane transport
FP497_RS10170	COG1653	transport
FP497_RS10175	COG0366	Alpha amylase catalytic
FP497_RS10180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FP497_RS10190	COG1983	PspC domain protein
FP497_RS10200	COG1842	Phage shock protein A
FP497_RS10205	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FP497_RS10210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FP497_RS10215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FP497_RS10220	COG1012	belongs to the aldehyde dehydrogenase family
FP497_RS10225	COG1917	Cupin 2, conserved barrel domain protein
FP497_RS10225	COG1396	sequence-specific DNA binding
FP497_RS10230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FP497_RS10235	COG0174	glutamine synthetase
FP497_RS10245	COG0531	amino acid
FP497_RS10255	COG4166	transmembrane transport
FP497_RS10260	COG4168	peptide transport system, permease
FP497_RS10265	COG4171	peptide transport system, permease
FP497_RS10270	COG4172	Belongs to the ABC transporter superfamily
FP497_RS10275	COG4172	Belongs to the ABC transporter superfamily
FP497_RS10280	COG2852	Protein conserved in bacteria
FP497_RS10285	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FP497_RS10290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FP497_RS10290	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FP497_RS10305	COG5001	Diguanylate cyclase
FP497_RS10315	COG1349	DNA-binding transcription factor activity
FP497_RS10325	COG0023	Translation Initiation Factor
FP497_RS10335	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FP497_RS10340	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FP497_RS10345	COG0671	phosphoesterase, PA-phosphatase related
FP497_RS10355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FP497_RS10375	COG0583	DNA-binding transcription factor activity
FP497_RS10380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FP497_RS10390	COG0616	signal peptide processing
FP497_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS10400	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FP497_RS10405	COG1187	pseudouridine synthase activity
FP497_RS10410	COG4907	membrane protein (DUF2207)
FP497_RS10415	COG0009	L-threonylcarbamoyladenylate synthase
FP497_RS10420	COG0613	PHP domain protein
FP497_RS10430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FP497_RS10435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FP497_RS10435	COG0512	Glutamine amidotransferase of anthranilate synthase
FP497_RS10440	COG0134	indole-3-glycerol-phosphate synthase activity
FP497_RS10440	COG0135	phosphoribosylanthranilate isomerase activity
FP497_RS10455	COG3729	General stress protein
FP497_RS10460	COG3685	Protein conserved in bacteria
FP497_RS10465	COG3685	Protein conserved in bacteria
FP497_RS10470	COG3047	cAMP biosynthetic process
FP497_RS10490	COG1607	acyl-coa hydrolase
FP497_RS10495	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FP497_RS10500	COG2350	Protein conserved in bacteria
FP497_RS10505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FP497_RS10525	COG4608	Belongs to the ABC transporter superfamily
FP497_RS10530	COG0444	Belongs to the ABC transporter superfamily
FP497_RS10535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FP497_RS10540	COG0601	transmembrane transport
FP497_RS10545	COG4166	transmembrane transport
FP497_RS10550	COG2095	MarC family integral membrane protein
FP497_RS10555	COG1012	belongs to the aldehyde dehydrogenase family
FP497_RS10555	COG1454	alcohol dehydrogenase
FP497_RS10565	COG1435	thymidine kinase activity
FP497_RS10575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FP497_RS10580	COG0745	RESPONSE REGULATOR receiver
FP497_RS10585	COG1752	Esterase of the alpha-beta hydrolase superfamily
FP497_RS10595	COG0788	formyltetrahydrofolate deformylase activity
FP497_RS10630	COG2181	nitrate reductase activity
FP497_RS10635	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FP497_RS10640	COG1140	nitrate reductase beta subunit
FP497_RS10645	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FP497_RS10650	COG2223	nitrite transmembrane transporter activity
FP497_RS10655	COG3850	Histidine kinase
FP497_RS10660	COG2197	response regulator
FP497_RS10665	COG4932	domain protein
FP497_RS10670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FP497_RS10675	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FP497_RS10680	COG4572	Cation transport regulator
FP497_RS10685	COG0387	Pfam Sodium calcium exchanger
FP497_RS10725	COG2912	Transglutaminase-like superfamily
FP497_RS10730	COG3094	Invasion gene expression up-regulator, SirB
FP497_RS10735	COG2890	protein-(glutamine-N5) methyltransferase activity
FP497_RS10760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FP497_RS10765	COG0659	secondary active sulfate transmembrane transporter activity
FP497_RS10780	COG0012	GTP binding
FP497_RS10785	COG3468	outer membrane autotransporter barrel domain protein
FP497_RS10790	COG3284	Transcriptional regulator
FP497_RS10795	COG2376	Dihydroxyacetone kinase
FP497_RS10800	COG1461	Dihydroxyacetone kinase
FP497_RS10805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS10805	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FP497_RS10805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FP497_RS10820	COG2261	transglycosylase associated protein
FP497_RS10825	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FP497_RS10835	COG1619	proteins homologs of microcin C7 resistance protein MccF
FP497_RS10845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FP497_RS10855	COG2719	SpoVR family
FP497_RS10870	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FP497_RS10875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FP497_RS10880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FP497_RS10895	COG0179	Fumarylacetoacetate (FAA) hydrolase
FP497_RS10920	COG2894	cell division
FP497_RS10950	COG0538	isocitrate dehydrogenase activity
FP497_RS10955	COG1187	pseudouridine synthase activity
FP497_RS10975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FP497_RS10980	COG0745	RESPONSE REGULATOR receiver
FP497_RS10985	COG2205	protein histidine kinase activity
FP497_RS10990	COG2850	peptidyl-arginine hydroxylation
FP497_RS11000	COG3842	ATPase activity
FP497_RS11010	COG1177	transmembrane transport
FP497_RS11015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FP497_RS11025	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FP497_RS11030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FP497_RS11040	COG4591	ABC-type transport system involved in lipoprotein release permease component
FP497_RS11045	COG1136	(ABC) transporter
FP497_RS11050	COG4591	ABC-type transport system involved in lipoprotein release permease component
FP497_RS11055	COG4763	Acyl-transferase
FP497_RS11060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FP497_RS11065	COG1376	ErfK ybiS ycfS ynhG family protein
FP497_RS11065	COG1388	LysM domain
FP497_RS11075	COG1309	transcriptional regulator
FP497_RS11080	COG3134	Outer membrane lipoprotein
FP497_RS11085	COG1252	NADH dehydrogenase
FP497_RS11105	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FP497_RS11110	COG5633	Lipoprotein
FP497_RS11115	COG0537	adenosine 5'-monophosphoramidase activity
FP497_RS11120	COG4773	Receptor
FP497_RS11125	COG1263	PTS System
FP497_RS11125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS11130	COG0084	hydrolase, TatD family'
FP497_RS11135	COG0470	DNA polymerase III
FP497_RS11145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FP497_RS11150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FP497_RS11155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FP497_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS11170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FP497_RS11190	COG1399	metal-binding, possibly nucleic acid-binding protein
FP497_RS11195	COG0424	maF-like protein
FP497_RS11200	COG0564	pseudouridine synthase activity
FP497_RS11205	COG1530	ribonuclease E activity
FP497_RS11210	COG0728	peptidoglycan biosynthetic process
FP497_RS11215	COG0673	inositol 2-dehydrogenase activity
FP497_RS11225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FP497_RS11235	COG2999	glutathione oxidoreductase activity
FP497_RS11270	COG3038	cytochrome b561
FP497_RS11275	COG2353	YceI-like domain
FP497_RS11285	COG1560	Kdo2-lipid A biosynthetic process
FP497_RS11300	COG5645	(Lipo)protein
FP497_RS11305	COG2943	transferase activity, transferring hexosyl groups
FP497_RS11320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FP497_RS11325	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FP497_RS11350	COG2197	response regulator
FP497_RS11365	COG1462	curli production assembly transport component CsgG
FP497_RS11375	COG3381	protein complex oligomerization
FP497_RS11400	COG1702	phosphate starvation-inducible protein PhoH
FP497_RS11405	COG2837	iron assimilation
FP497_RS11410	COG2822	iron ion transport
FP497_RS11420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FP497_RS11430	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FP497_RS11430	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FP497_RS11430	COG0506	proline dehydrogenase activity
FP497_RS11435	COG1309	transcriptional regulator
FP497_RS11475	COG2233	PERMEase
FP497_RS11480	COG3729	General stress protein
FP497_RS11515	COG3381	protein complex oligomerization
FP497_RS11520	COG0243	molybdopterin cofactor binding
FP497_RS11525	COG3005	denitrification pathway
FP497_RS11530	COG0745	RESPONSE REGULATOR receiver
FP497_RS11535	COG1879	ABC-type sugar transport system periplasmic component
FP497_RS11540	COG2205	protein histidine kinase activity
FP497_RS11540	COG2198	Histidine kinase
FP497_RS11540	COG0784	Response regulator, receiver
FP497_RS11545	COG0348	domain, Protein
FP497_RS11565	COG1278	Cold shock
FP497_RS11570	COG1278	Cold shock
FP497_RS11585	COG1294	oxidase, subunit
FP497_RS11590	COG1271	oxidase subunit
FP497_RS11595	COG1773	rubredoxin
FP497_RS11600	COG1999	signal sequence binding
FP497_RS11605	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FP497_RS11610	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FP497_RS11615	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FP497_RS11620	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FP497_RS11630	COG0670	Belongs to the BI1 family
FP497_RS11635	COG2920	part of a sulfur-relay system
FP497_RS11640	COG1254	Belongs to the acylphosphatase family
FP497_RS11655	COG1832	CoA-binding protein
FP497_RS11670	COG0210	DNA helicase
FP497_RS11675	COG3304	Inner membrane component domain
FP497_RS11680	COG1289	transmembrane transporter activity
FP497_RS11685	COG3070	regulator of competence-specific genes
FP497_RS11695	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FP497_RS11695	COG2885	chlorophyll binding
FP497_RS11705	COG1067	ATP-dependent peptidase activity
FP497_RS11715	COG3130	regulation of translation
FP497_RS11720	COG3009	Protein conserved in bacteria
FP497_RS11725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FP497_RS11725	COG3008	intermembrane lipid transfer
FP497_RS11730	COG2995	paraquat-inducible protein a
FP497_RS11735	COG0488	(ABC) transporter
FP497_RS11745	COG0633	Ferredoxin
FP497_RS11745	COG3217	Mosc domain protein beta barrel domain protein
FP497_RS11760	COG3121	Chaperone
FP497_RS11765	COG3539	Fimbrial protein
FP497_RS11770	COG3539	Fimbrial protein
FP497_RS11775	COG3539	Fimbrial protein
FP497_RS11780	COG3188	usher protein
FP497_RS11785	COG3121	Chaperone
FP497_RS11790	COG3539	Fimbrial protein
FP497_RS11795	COG0431	NADPH-dependent FMN reductase
FP497_RS11800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FP497_RS11810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FP497_RS11815	COG1116	anion transmembrane transporter activity
FP497_RS11820	COG0308	aminopeptidase N
FP497_RS11840	COG1448	Aminotransferase
FP497_RS11845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FP497_RS11850	COG3108	Peptidase M15
FP497_RS11855	COG2989	Protein conserved in bacteria
FP497_RS11865	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FP497_RS11875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FP497_RS11880	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FP497_RS11885	COG3173	Aminoglycoside phosphotransferase
FP497_RS11900	COG3214	Protein conserved in bacteria
FP497_RS11905	COG1663	tetraacyldisaccharide 4'-kinase activity
FP497_RS11910	COG1132	(ABC) transporter
FP497_RS11915	COG2333	competence protein COMEC
FP497_RS11915	COG0658	competence protein
FP497_RS11925	COG0539	negative regulation of cytoplasmic translation
FP497_RS11935	COG0501	Belongs to the peptidase M48B family
FP497_RS11950	COG2323	membrane
FP497_RS11955	COG1944	ATP diphosphatase activity
FP497_RS11960	COG2116	formate transmembrane transporter activity
FP497_RS11965	COG1882	Formate acetyltransferase
FP497_RS11970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FP497_RS11975	COG2249	NAD(P)H dehydrogenase (quinone) activity
FP497_RS11980	COG0583	DNA-binding transcription factor activity
FP497_RS11985	COG0531	amino acid
FP497_RS11995	COG1335	isochorismatase
FP497_RS12000	COG3302	dmso reductase anchor subunit
FP497_RS12005	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS12010	COG0243	molybdopterin cofactor binding
FP497_RS12020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FP497_RS12030	COG1178	ABC-type Fe3 transport system permease component
FP497_RS12030	COG1674	ftsk spoiiie
FP497_RS12035	COG1522	sequence-specific DNA binding
FP497_RS12040	COG0492	ferredoxin-NADP+ reductase activity
FP497_RS12045	COG4988	ABC transporter
FP497_RS12050	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FP497_RS12075	COG0542	response to heat
FP497_RS12085	COG1278	Cold shock
FP497_RS12090	COG0577	efflux transmembrane transporter activity
FP497_RS12090	COG1136	(ABC) transporter
FP497_RS12095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FP497_RS12100	COG2990	Protein conserved in bacteria
FP497_RS12105	COG3593	DNA synthesis involved in DNA repair
FP497_RS12115	COG2431	L-lysine efflux transmembrane transporter activity
FP497_RS12125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FP497_RS12130	COG0028	Belongs to the TPP enzyme family
FP497_RS12135	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FP497_RS12140	COG0702	epimerase
FP497_RS12145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FP497_RS12150	COG3023	N-Acetylmuramoyl-L-alanine amidase
FP497_RS12165	COG1126	abc transporter atp-binding protein
FP497_RS12170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FP497_RS12175	COG4215	(ABC) transporter
FP497_RS12180	COG4160	amino acid transport
FP497_RS12185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FP497_RS12200	COG1177	transmembrane transport
FP497_RS12205	COG1176	ABC-type spermidine putrescine transport system, permease component I
FP497_RS12210	COG3842	ATPase activity
FP497_RS12215	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FP497_RS12230	COG0778	Nitroreductase
FP497_RS12240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FP497_RS12255	COG3226	Transcriptional regulator
FP497_RS12260	COG0738	Major facilitator superfamily
FP497_RS12265	COG0561	phosphatase activity
FP497_RS12275	COG2814	Major facilitator Superfamily
FP497_RS12280	COG0671	phosphoesterase, PA-phosphatase related
FP497_RS12285	COG1349	DNA-binding transcription factor activity
FP497_RS12290	COG1686	Belongs to the peptidase S11 family
FP497_RS12295	COG0625	glutathione transferase activity
FP497_RS12300	COG2133	pyrroloquinoline quinone binding
FP497_RS12315	COG2199	diguanylate cyclase activity
FP497_RS12320	COG2200	EAL domain
FP497_RS12325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FP497_RS12335	COG0747	negative chemotaxis
FP497_RS12340	COG4172	Belongs to the ABC transporter superfamily
FP497_RS12345	COG1446	asparaginase
FP497_RS12350	COG0303	'Molybdopterin
FP497_RS12355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FP497_RS12360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FP497_RS12365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FP497_RS12370	COG1882	Formate acetyltransferase
FP497_RS12375	COG0561	phosphatase activity
FP497_RS12385	COG0488	(ABC) transporter
FP497_RS12390	COG1376	ErfK ybiS ycfS ynhG family protein
FP497_RS12395	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FP497_RS12400	COG1321	iron dependent repressor
FP497_RS12410	COG2194	sulfuric ester hydrolase activity
FP497_RS12415	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FP497_RS12425	COG5006	permease, DMT superfamily
FP497_RS12435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FP497_RS12440	COG0765	amino acid transport
FP497_RS12445	COG1126	abc transporter atp-binding protein
FP497_RS12450	COG0668	transmembrane transport
FP497_RS12465	COG4774	siderophore transport
FP497_RS12475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FP497_RS12485	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FP497_RS12490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FP497_RS12495	COG1199	ATP-dependent helicase activity
FP497_RS12500	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FP497_RS12505	COG0513	Belongs to the DEAD box helicase family
FP497_RS12510	COG1309	transcriptional regulator
FP497_RS12520	COG1131	(ABC) transporter
FP497_RS12525	COG0842	Transport permease protein
FP497_RS12530	COG0842	Transport permease protein
FP497_RS12540	COG3568	Endonuclease Exonuclease Phosphatase
FP497_RS12545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FP497_RS12550	COG0392	lysyltransferase activity
FP497_RS12555	COG0670	Belongs to the BI1 family
FP497_RS12560	COG0670	Belongs to the BI1 family
FP497_RS12565	COG0314	molybdopterin synthase activity
FP497_RS12570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FP497_RS12580	COG0521	Mo-molybdopterin cofactor biosynthetic process
FP497_RS12590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FP497_RS12600	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FP497_RS12605	COG2226	methyltransferase
FP497_RS12620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FP497_RS12625	COG1881	PFAM PEBP family protein
FP497_RS12630	COG4677	pectinesterase activity
FP497_RS12635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FP497_RS12640	COG0471	metal ion transport
FP497_RS12645	COG2828	Protein conserved in bacteria
FP497_RS12650	COG0583	DNA-binding transcription factor activity
FP497_RS12660	COG0561	phosphatase activity
FP497_RS12665	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FP497_RS12670	COG4149	molybdate abc transporter
FP497_RS12675	COG0725	ABC transporter, periplasmic molybdate-binding protein
FP497_RS12685	COG3585	molybdate ion transport
FP497_RS12685	COG2005	Transcriptional regulator
FP497_RS12690	COG1119	ATPase activity
FP497_RS12695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FP497_RS12700	COG1085	galactose-1-phosphate uridylyltransferase
FP497_RS12710	COG2017	converts alpha-aldose to the beta-anomer
FP497_RS12720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FP497_RS12730	COG1230	cation diffusion facilitator family transporter
FP497_RS12735	COG3201	nicotinamide mononucleotide transporter
FP497_RS12785	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FP497_RS12790	COG2885	chlorophyll binding
FP497_RS12800	COG3064	Membrane
FP497_RS12805	COG0848	biopolymer transport protein
FP497_RS12810	COG0811	peptide transport
FP497_RS12815	COG0824	Thioesterase
FP497_RS12820	COG3790	cyd operon protein YbgE
FP497_RS12825	COG4890	Cyd operon protein YbgT
FP497_RS12830	COG1294	oxidase, subunit
FP497_RS12835	COG1271	oxidase subunit
FP497_RS12840	COG0383	alpha-mannosidase activity
FP497_RS12845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS12845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS12845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS12850	COG2188	Transcriptional regulator
FP497_RS12855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FP497_RS12865	COG0508	dehydrogenase complex catalyzes the overall conversion of
FP497_RS12870	COG0567	Dehydrogenase, E1 component
FP497_RS12875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FP497_RS12880	COG1053	succinate dehydrogenase
FP497_RS12885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FP497_RS12890	COG2009	succinate dehydrogenase
FP497_RS12900	COG0372	Belongs to the citrate synthase family
FP497_RS12905	COG3539	Fimbrial protein
FP497_RS12910	COG3188	usher protein
FP497_RS12915	COG3121	Chaperone
FP497_RS12920	COG3539	Fimbrial protein
FP497_RS12925	COG3180	Ammonia monooxygenase
FP497_RS12940	COG1984	allophanate hydrolase subunit 2
FP497_RS12945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FP497_RS12950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FP497_RS12955	COG3104	oligopeptide transport
FP497_RS12960	COG0415	Belongs to the DNA photolyase family
FP497_RS12965	COG3272	Protein of unknown function (DUF1722)
FP497_RS12995	COG2205	protein histidine kinase activity
FP497_RS13000	COG0745	RESPONSE REGULATOR receiver
FP497_RS13010	COG1982	Orn Lys Arg decarboxylase major
FP497_RS13015	COG0531	amino acid
FP497_RS13035	COG0033	Phosphoglucomutase
FP497_RS13040	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FP497_RS13045	COG0596	Alpha beta hydrolase
FP497_RS13055	COG0716	FMN binding
FP497_RS13065	COG0735	belongs to the Fur family
FP497_RS13085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS13085	COG2190	(PTS) system
FP497_RS13085	COG1263	PTS System
FP497_RS13095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FP497_RS13100	COG1846	Transcriptional regulator
FP497_RS13100	COG1940	carbohydrate kinase activity
FP497_RS13105	COG0647	UMP catabolic process
FP497_RS13110	COG0367	asparagine synthase
FP497_RS13150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FP497_RS13160	COG1702	phosphate starvation-inducible protein PhoH
FP497_RS13170	COG4535	Mg2 and Co2 transporter CorC
FP497_RS13175	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FP497_RS13180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FP497_RS13185	COG0765	amino acid transport
FP497_RS13190	COG0765	amino acid transport
FP497_RS13195	COG1126	abc transporter atp-binding protein
FP497_RS13205	COG0443	Heat shock 70 kDa protein
FP497_RS13210	COG2214	Heat shock protein DnaJ domain protein
FP497_RS13220	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FP497_RS13225	COG2214	Heat shock protein DnaJ domain protein
FP497_RS13235	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FP497_RS13240	COG2888	peptidyl-tyrosine sulfation
FP497_RS13255	COG1466	dna polymerase III delta subunit
FP497_RS13265	COG0406	alpha-ribazole phosphatase activity
FP497_RS13270	COG0799	negative regulation of ribosome biogenesis
FP497_RS13280	COG0768	penicillin binding
FP497_RS13285	COG0772	Belongs to the SEDS family
FP497_RS13290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FP497_RS13295	COG1686	Belongs to the peptidase S11 family
FP497_RS13310	COG0583	DNA-binding transcription factor activity
FP497_RS13320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FP497_RS13345	COG3069	C4-dicarboxylate transmembrane transporter activity
FP497_RS13350	COG4565	transcriptional regulatory protein
FP497_RS13355	COG3290	protein histidine kinase activity
FP497_RS13360	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FP497_RS13370	COG2301	Belongs to the HpcH HpaI aldolase family
FP497_RS13375	COG3051	citrate lyase alpha subunit
FP497_RS13390	COG0471	metal ion transport
FP497_RS13395	COG3719	Belongs to the RNase T2 family
FP497_RS13400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FP497_RS13405	COG1063	alcohol dehydrogenase
FP497_RS13410	COG0589	response to stress
FP497_RS13415	COG3634	alkyl hydroperoxide reductase activity
FP497_RS13420	COG0450	alkyl hydroperoxide reductase
FP497_RS13425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FP497_RS13430	COG0583	DNA-binding transcription factor activity
FP497_RS13435	COG3969	phosphoadenosine phosphosulfate
FP497_RS13440	COG1475	DNA binding
FP497_RS13445	COG0436	Aminotransferase
FP497_RS13450	COG0371	Dehydrogenase
FP497_RS13455	COG2879	small protein
FP497_RS13460	COG1966	Carbon starvation protein
FP497_RS13465	COG2050	protein possibly involved in aromatic compounds catabolism
FP497_RS13470	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS13475	COG1535	isochorismatase
FP497_RS13475	COG3433	isochorismatase activity
FP497_RS13480	COG1021	2,3-dihydroxybenzoate-AMP ligase
FP497_RS13485	COG1169	isochorismate synthase
FP497_RS13490	COG4592	Periplasmic binding protein
FP497_RS13500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FP497_RS13505	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FP497_RS13510	COG1120	ATPase activity
FP497_RS13515	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FP497_RS13520	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FP497_RS13520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FP497_RS13525	COG3251	PFAM MbtH domain protein
FP497_RS13530	COG2382	esterase
FP497_RS13535	COG4771	TonB-dependent receptor
FP497_RS13540	COG2977	Belongs to the P-Pant transferase superfamily
FP497_RS13545	COG1113	amino acid transport
FP497_RS13550	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FP497_RS13555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FP497_RS13560	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FP497_RS13565	COG1538	Outer membrane efflux protein
FP497_RS13570	COG0745	RESPONSE REGULATOR receiver
FP497_RS13575	COG5002	protein histidine kinase activity
FP497_RS13580	COG1215	transferase activity, transferring glycosyl groups
FP497_RS13585	COG4783	chaperone-mediated protein folding
FP497_RS13595	COG2207	Transcriptional regulator
FP497_RS13610	COG2197	response regulator
FP497_RS13615	COG3539	Fimbrial protein
FP497_RS13620	COG3539	Fimbrial protein
FP497_RS13625	COG3188	usher protein
FP497_RS13630	COG3121	Chaperone
FP497_RS13635	COG3539	Fimbrial protein
FP497_RS13645	COG2501	S4 domain
FP497_RS13650	COG1988	membrane-bound metal-dependent
FP497_RS13660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FP497_RS13670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FP497_RS13675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FP497_RS13680	COG0549	Belongs to the carbamate kinase family
FP497_RS13690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FP497_RS13695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FP497_RS13700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FP497_RS13705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FP497_RS13710	COG3257	ureidoglycine aminohydrolase activity
FP497_RS13715	COG1929	Belongs to the glycerate kinase type-1 family
FP497_RS13720	COG2233	PERMEase
FP497_RS13730	COG1953	Uracil, thiamine, allantoin
FP497_RS13735	COG2084	Dehydrogenase
FP497_RS13740	COG3622	Belongs to the hyi family
FP497_RS13745	COG3960	tartronate-semialdehyde synthase activity
FP497_RS13750	COG1414	Transcriptional regulator
FP497_RS13760	COG0583	DNA-binding transcription factor activity
FP497_RS13770	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FP497_RS13775	COG4181	ATPase activity
FP497_RS13780	COG2755	lipolytic protein G-D-S-L family
FP497_RS13785	COG0300	oxidoreductase activity
FP497_RS13790	COG3118	belongs to the thioredoxin family
FP497_RS13795	COG0390	transport system, permease component
FP497_RS13800	COG4619	ABC transporter
FP497_RS13805	COG0330	HflC and HflK could
FP497_RS13810	COG1585	Membrane protein implicated in regulation of membrane protease activity
FP497_RS13815	COG0789	Transcriptional regulator
FP497_RS13820	COG0531	amino acid
FP497_RS13825	COG2066	Belongs to the glutaminase family
FP497_RS13830	COG2217	Heavy metal translocating P-type atpase
FP497_RS13835	COG3093	addiction module antidote protein HigA
FP497_RS13845	COG3735	TraB family
FP497_RS13850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FP497_RS13855	COG0737	Belongs to the 5'-nucleotidase family
FP497_RS13860	COG2223	nitrite transmembrane transporter activity
FP497_RS13865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FP497_RS13865	COG4651	solute:proton antiporter activity
FP497_RS13870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS13910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FP497_RS13920	COG2832	Protein of unknown function (DUF454)
FP497_RS13925	COG3923	Primosomal replication protein n
FP497_RS13935	COG3264	Mechanosensitive ion channel
FP497_RS13935	COG1196	nuclear chromosome segregation
FP497_RS13940	COG1309	transcriptional regulator
FP497_RS13945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FP497_RS13950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FP497_RS13965	COG0110	maltose O-acetyltransferase activity
FP497_RS13975	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FP497_RS13980	COG5507	3-demethylubiquinone-9 3-methyltransferase
FP497_RS13990	COG3695	enzyme binding
FP497_RS13995	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FP497_RS14000	COG1946	Acyl-CoA thioesterase
FP497_RS14005	COG0004	ammonium transporteR
FP497_RS14010	COG0347	Belongs to the P(II) protein family
FP497_RS14015	COG1132	(ABC) transporter
FP497_RS14020	COG1132	(ABC) transporter
FP497_RS14025	COG1522	sequence-specific DNA binding
FP497_RS14035	COG4533	DNA binding
FP497_RS14045	COG0824	Thioesterase
FP497_RS14050	COG1555	photosystem II stabilization
FP497_RS14055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FP497_RS14060	COG0776	regulation of translation
FP497_RS14065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FP497_RS14085	COG0271	Belongs to the BolA IbaG family
FP497_RS14090	COG3056	Lipoprotein
FP497_RS14095	COG2223	nitrite transmembrane transporter activity
FP497_RS14100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FP497_RS14105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FP497_RS14110	COG1845	cytochrome c oxidase, subunit III
FP497_RS14115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FP497_RS14125	COG2814	Major facilitator Superfamily
FP497_RS14135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FP497_RS14140	COG0693	protein deglycase activity
FP497_RS14155	COG0142	geranyltranstransferase activity
FP497_RS14165	COG0667	Aldo Keto reductase
FP497_RS14170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FP497_RS14175	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FP497_RS14190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FP497_RS14190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FP497_RS14200	COG4238	major outer membrane lipoprotein
FP497_RS14205	COG3248	Nucleoside-binding outer membrane protein
FP497_RS14210	COG1403	HNH endonuclease
FP497_RS14215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FP497_RS14220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FP497_RS14225	COG1862	Preprotein translocase
FP497_RS14245	COG0366	Alpha amylase catalytic
FP497_RS14250	COG1113	amino acid transport
FP497_RS14255	COG1114	Component of the transport system for branched-chain amino acids
FP497_RS14260	COG5002	protein histidine kinase activity
FP497_RS14265	COG0745	RESPONSE REGULATOR receiver
FP497_RS14270	COG0420	3'-5' exonuclease activity
FP497_RS14275	COG0419	ATPase involved in DNA repair
FP497_RS14280	COG2814	Major facilitator Superfamily
FP497_RS14285	COG1940	carbohydrate kinase activity
FP497_RS14310	COG4126	flavin adenine dinucleotide binding
FP497_RS14330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FP497_RS14335	COG3706	GGDEF domain
FP497_RS14345	COG1785	Belongs to the alkaline phosphatase family
FP497_RS14355	COG1181	Belongs to the D-alanine--D-alanine ligase family
FP497_RS14360	COG0113	porphobilinogen synthase activity
FP497_RS14370	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FP497_RS14380	COG3122	Protein conserved in bacteria
FP497_RS14385	COG2814	Major facilitator Superfamily
FP497_RS14400	COG3971	2-oxopent-4-enoate hydratase activity
FP497_RS14420	COG1414	Transcriptional regulator
FP497_RS14425	COG1609	Transcriptional regulator
FP497_RS14430	COG3250	beta-galactosidase activity
FP497_RS14435	COG2223	nitrite transmembrane transporter activity
FP497_RS14440	COG0110	maltose O-acetyltransferase activity
FP497_RS14445	COG2807	transmembrane transport
FP497_RS14455	COG0288	reversible hydration of carbon dioxide
FP497_RS14460	COG0583	DNA-binding transcription factor activity
FP497_RS14465	COG0402	S-adenosylhomocysteine deaminase activity
FP497_RS14470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FP497_RS14475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FP497_RS14480	COG2079	MmgE PrpD family protein
FP497_RS14485	COG0372	Belongs to the citrate synthase family
FP497_RS14490	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FP497_RS14495	COG3829	transcription factor binding
FP497_RS14505	COG1280	lysine exporter protein (LysE YggA)
FP497_RS14520	COG1064	alcohol dehydrogenase
FP497_RS14525	COG0402	S-adenosylhomocysteine deaminase activity
FP497_RS14530	COG0549	Belongs to the carbamate kinase family
FP497_RS14540	COG1304	FMN binding
FP497_RS14545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FP497_RS14555	COG0666	response to abiotic stimulus
FP497_RS14565	COG0583	DNA-binding transcription factor activity
FP497_RS14570	COG2771	luxR family
FP497_RS14570	COG2200	EAL domain
FP497_RS14580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FP497_RS14620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FP497_RS14640	COG2195	Cleaves the N-terminal amino acid of tripeptides
FP497_RS14645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FP497_RS14650	COG1690	Belongs to the RtcB family
FP497_RS14655	COG0454	-acetyltransferase
FP497_RS14665	COG2161	toxin-antitoxin pair type II binding
FP497_RS14685	COG1943	Transposase
FP497_RS14690	COG0791	NLP P60 protein
FP497_RS14695	COG3077	Addiction module antitoxin, RelB DinJ family
FP497_RS14700	COG3041	Addiction module toxin RelE StbE family
FP497_RS14705	COG3034	peptidoglycan biosynthetic process
FP497_RS14710	COG0121	glutamine amidotransferase
FP497_RS14720	COG1960	acyl-CoA dehydrogenase activity
FP497_RS14730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FP497_RS14760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FP497_RS14770	COG2226	methyltransferase
FP497_RS14780	COG0741	lytic transglycosylase activity
FP497_RS14780	COG1388	LysM domain
FP497_RS14785	COG2226	methyltransferase
FP497_RS14795	COG0583	DNA-binding transcription factor activity
FP497_RS14800	COG0656	L-ascorbic acid biosynthetic process
FP497_RS14835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FP497_RS14840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FP497_RS14845	COG2011	ABC-type metal ion transport system permease component
FP497_RS14850	COG1464	Belongs to the NlpA lipoprotein family
FP497_RS14860	COG1720	tRNA m6t6A37 methyltransferase activity
FP497_RS14870	COG0791	NLP P60 protein
FP497_RS14875	COG3015	lipoprotein NlpE involved in copper resistance
FP497_RS14880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FP497_RS14885	COG4681	YaeQ
FP497_RS14895	COG4568	rho-dependent transcription termination
FP497_RS14900	COG0037	tRNA processing
FP497_RS14905	COG0346	lactoylglutathione lyase activity
FP497_RS14910	COG1982	Orn Lys Arg decarboxylase major
FP497_RS14920	COG0587	DNA-directed DNA polymerase activity
FP497_RS14945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FP497_RS14950	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FP497_RS14960	COG0750	zinc metalloprotease
FP497_RS14965	COG0575	Belongs to the CDS family
FP497_RS14970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FP497_RS14975	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FP497_RS15000	COG0024	Methionine aminopeptidase
FP497_RS15015	COG1408	metallophosphoesterase
FP497_RS15030	COG3835	regulator
FP497_RS15035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FP497_RS15050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FP497_RS15055	COG2860	membrane
FP497_RS15080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FP497_RS15085	COG1643	Atp-dependent helicase
FP497_RS15090	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FP497_RS15100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FP497_RS15110	COG0617	tRNA 3'-terminal CCA addition
FP497_RS15115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FP497_RS15120	COG3539	Fimbrial protein
FP497_RS15125	COG3121	Chaperone
FP497_RS15130	COG3188	usher protein
FP497_RS15135	COG3539	Fimbrial protein
FP497_RS15140	COG3539	Fimbrial protein
FP497_RS15145	COG3539	Fimbrial protein
FP497_RS15150	COG3539	Fimbrial protein
FP497_RS15165	COG5464	transposase or invertase
FP497_RS15175	COG0726	polysaccharide deacetylase
FP497_RS15180	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS15185	COG0842	Transport permease protein
FP497_RS15190	COG1131	(ABC) transporter
FP497_RS15195	COG0288	reversible hydration of carbon dioxide
FP497_RS15200	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FP497_RS15205	COG4993	Dehydrogenase
FP497_RS15210	COG2132	Multicopper oxidase
FP497_RS15235	COG1049	propionate catabolic process, 2-methylcitrate cycle
FP497_RS15240	COG3064	Membrane
FP497_RS15245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FP497_RS15250	COG0508	dehydrogenase complex catalyzes the overall conversion of
FP497_RS15255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FP497_RS15260	COG2186	Transcriptional regulator
FP497_RS15265	COG1113	amino acid transport
FP497_RS15270	COG3725	Membrane protein required for beta-lactamase induction
FP497_RS15275	COG3023	N-Acetylmuramoyl-L-alanine amidase
FP497_RS15280	COG0157	Belongs to the NadC ModD family
FP497_RS15285	COG4969	Belongs to the N-Me-Phe pilin family
FP497_RS15290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FP497_RS15295	COG1459	type II secretion system
FP497_RS15305	COG0237	dephospho-CoA kinase activity
FP497_RS15320	COG0494	nUDIX hydrolase
FP497_RS15340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FP497_RS15345	COG0849	cell division
FP497_RS15350	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FP497_RS15355	COG1181	Belongs to the D-alanine--D-alanine ligase family
FP497_RS15370	COG0772	Belongs to the SEDS family
FP497_RS15375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FP497_RS15385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FP497_RS15390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FP497_RS15395	COG0768	penicillin binding
FP497_RS15400	COG3116	cell division
FP497_RS15410	COG2001	Belongs to the MraZ family
FP497_RS15415	COG1609	Transcriptional regulator
FP497_RS15425	COG0440	acetolactate synthase activity
FP497_RS15430	COG0028	Belongs to the TPP enzyme family
FP497_RS15440	COG0583	DNA-binding transcription factor activity
FP497_RS15455	COG0473	3-isopropylmalate dehydrogenase activity
FP497_RS15470	COG2814	Major facilitator Superfamily
FP497_RS15480	COG4533	DNA binding
FP497_RS15485	COG4143	(ABC) transporter
FP497_RS15490	COG1178	ABC-type Fe3 transport system permease component
FP497_RS15495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FP497_RS15500	COG0586	Pfam SNARE associated Golgi protein
FP497_RS15505	COG4977	sequence-specific DNA binding
FP497_RS15510	COG1069	ribulokinase activity
FP497_RS15515	COG2160	L-arabinose isomerase activity
FP497_RS15520	COG0235	Class ii aldolase
FP497_RS15525	COG0417	DNA replication proofreading
FP497_RS15535	COG0564	pseudouridine synthase activity
FP497_RS15545	COG1357	PFAM Pentapeptide repeats (8 copies)
FP497_RS15550	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FP497_RS15555	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FP497_RS15560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FP497_RS15585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FP497_RS15600	COG2271	Major facilitator Superfamily
FP497_RS15605	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FP497_RS15610	COG0644	oxidoreductase
FP497_RS15660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FP497_RS15665	COG0505	Belongs to the CarA family
FP497_RS15685	COG1047	Peptidyl-prolyl cis-trans
FP497_RS15700	COG0196	riboflavin kinase activity
FP497_RS15730	COG4735	regulation of single-species biofilm formation
FP497_RS15735	COG1584	GPR1 FUN34 yaaH family protein
FP497_RS15740	COG0521	Mo-molybdopterin cofactor biosynthetic process
FP497_RS15745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FP497_RS15750	COG1115	amino acid carrier protein
FP497_RS15765	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FP497_RS15775	COG0460	homoserine dehydrogenase
FP497_RS15775	COG0527	aspartate kinase activity
FP497_RS15785	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FP497_RS15795	COG0745	RESPONSE REGULATOR receiver
FP497_RS15800	COG4452	Inner membrane protein CreD
FP497_RS15805	COG2205	protein histidine kinase activity
FP497_RS15810	COG0745	RESPONSE REGULATOR receiver
FP497_RS15815	COG3045	CreA protein
FP497_RS15820	COG3708	Transcriptional regulator
FP497_RS15820	COG2207	Transcriptional regulator
FP497_RS15840	COG0741	lytic transglycosylase activity
FP497_RS15845	COG0488	(ABC) transporter
FP497_RS15850	COG3172	ATPase kinase involved in NAD metabolism
FP497_RS15850	COG1056	cytidyltransferase-related domain
FP497_RS15855	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FP497_RS15860	COG0560	Phosphoserine phosphatase
FP497_RS15865	COG3726	membrane protein affecting hemolysin expression
FP497_RS15875	COG3550	peptidyl-serine autophosphorylation
FP497_RS15900	COG1328	CTP reductase activity
FP497_RS15905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FP497_RS15910	COG0084	hydrolase, TatD family'
FP497_RS15915	COG4667	esterase of the alpha-beta hydrolase superfamily
FP497_RS15925	COG2823	Periplasmic or secreted lipoprotein
FP497_RS15935	COG1011	Hydrolase
FP497_RS15940	COG0456	acetyltransferase
FP497_RS15945	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FP497_RS15975	COG4114	ferric iron reductase
FP497_RS15980	COG2197	response regulator
FP497_RS15985	COG2197	response regulator
FP497_RS15990	COG2966	Psort location CytoplasmicMembrane, score
FP497_RS16005	COG1484	DNA-dependent DNA replication
FP497_RS16020	COG2186	Transcriptional regulator
FP497_RS16025	COG0246	Mannitol dehydrogenase
FP497_RS16035	COG2610	gluconate transmembrane transporter activity
FP497_RS16050	COG1064	alcohol dehydrogenase
FP497_RS16055	COG3265	gluconokinase activity
FP497_RS16060	COG1063	alcohol dehydrogenase
FP497_RS16065	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS16070	COG2610	gluconate transmembrane transporter activity
FP497_RS16075	COG1609	Transcriptional regulator
FP497_RS16080	COG0433	COG0433 Predicted ATPase
FP497_RS16085	COG0795	lipopolysaccharide-transporting ATPase activity
FP497_RS16090	COG0795	lipopolysaccharide-transporting ATPase activity
FP497_RS16100	COG2927	DNA polymerase III (CHI subunit)
FP497_RS16105	COG0525	valine-tRNA ligase activity
FP497_RS16110	COG4269	membrane
FP497_RS16115	COG0456	acetyltransferase
FP497_RS16120	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FP497_RS16125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FP497_RS16135	COG2731	YhcH YjgK YiaL family protein
FP497_RS16140	COG1309	transcriptional regulator
FP497_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
FP497_RS16150	COG0251	oxidation-reduction process
FP497_RS16170	COG0251	oxidation-reduction process
FP497_RS16175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FP497_RS16185	COG1609	Transcriptional regulator
FP497_RS16190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS16190	COG1263	PTS System
FP497_RS16195	COG0366	Alpha amylase catalytic
FP497_RS16200	COG1328	CTP reductase activity
FP497_RS16205	COG0602	queuosine metabolic process
FP497_RS16210	COG3783	Cytochrome b(562)
FP497_RS16215	COG0312	modulator of DNA gyrase
FP497_RS16225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FP497_RS16235	COG1172	Belongs to the binding-protein-dependent transport system permease family
FP497_RS16240	COG1172	Belongs to the binding-protein-dependent transport system permease family
FP497_RS16245	COG1129	ABC transporter
FP497_RS16250	COG1879	ABC-type sugar transport system periplasmic component
FP497_RS16255	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FP497_RS16260	COG2337	Toxic component of a toxin-antitoxin (TA) module
FP497_RS16265	COG2336	PFAM SpoVT AbrB
FP497_RS16270	COG2105	PFAM AIG2 family protein
FP497_RS16275	COG2911	Protein conserved in bacteria
FP497_RS16280	COG0729	surface antigen
FP497_RS16290	COG1253	flavin adenine dinucleotide binding
FP497_RS16300	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FP497_RS16310	COG1218	3'(2'),5'-bisphosphate nucleotidase
FP497_RS16315	COG0737	Belongs to the 5'-nucleotidase family
FP497_RS16320	COG1733	regulation of RNA biosynthetic process
FP497_RS16325	COG0702	epimerase
FP497_RS16330	COG0697	spore germination
FP497_RS16340	COG1113	amino acid transport
FP497_RS16345	COG0545	Peptidyl-prolyl cis-trans isomerase
FP497_RS16350	COG3061	Opacity-associated protein A
FP497_RS16370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FP497_RS16405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS16410	COG3414	Phosphotransferase system galactitol-specific IIB component
FP497_RS16415	COG3037	sugar-specific permease SgaT UlaA
FP497_RS16430	COG1073	alpha beta
FP497_RS16435	COG3650	response to hydrogen peroxide
FP497_RS16445	COG1960	acyl-CoA dehydrogenase activity
FP497_RS16450	COG0754	glutathionylspermidine amidase activity
FP497_RS16455	COG5463	Belongs to the UPF0441 family
FP497_RS16460	COG3766	membrane
FP497_RS16470	COG1842	Phage shock protein A
FP497_RS16475	COG3789	protein conserved in bacteria
FP497_RS16480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FP497_RS16485	COG0557	exoribonuclease II activity
FP497_RS16500	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FP497_RS16505	COG0330	HflC and HflK could
FP497_RS16510	COG0330	HflC and HflK could
FP497_RS16515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FP497_RS16535	COG0860	N-Acetylmuramoyl-L-alanine amidase
FP497_RS16540	COG0802	atpase or kinase
FP497_RS16545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FP497_RS16545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FP497_RS16550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FP497_RS16590	COG1511	domain protein
FP497_RS16590	COG3264	Mechanosensitive ion channel
FP497_RS16605	COG0531	amino acid
FP497_RS16615	COG1053	succinate dehydrogenase
FP497_RS16620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FP497_RS16635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FP497_RS16640	COG3040	lipid binding
FP497_RS16645	COG2076	Multidrug Resistance protein
FP497_RS16650	COG5510	response to toxic substance
FP497_RS16655	COG5510	response to toxic substance
FP497_RS16665	COG1509	lysine 2,3-aminomutase activity
FP497_RS16690	COG0531	amino acid
FP497_RS16695	COG3030	protein affecting phage T7 exclusion by the F plasmid
FP497_RS16700	COG1027	Aspartate ammonia-lyase
FP497_RS16705	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FP497_RS16715	COG4232	protein-disulfide reductase activity
FP497_RS16720	COG1309	transcriptional regulator
FP497_RS16730	COG3710	Transcriptional regulator
FP497_RS16735	COG0531	amino acid
FP497_RS16740	COG1982	Orn Lys Arg decarboxylase major
FP497_RS16745	COG3104	oligopeptide transport
FP497_RS16750	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FP497_RS16765	COG2388	GCN5-related N-acetyl-transferase
FP497_RS16770	COG3592	Divergent 4Fe-4S mono-cluster
FP497_RS16775	COG3290	protein histidine kinase activity
FP497_RS16780	COG4565	transcriptional regulatory protein
FP497_RS16785	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FP497_RS16790	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FP497_RS16790	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FP497_RS16795	COG3647	Membrane
FP497_RS16800	COG2211	Major facilitator Superfamily
FP497_RS16805	COG1486	melibiose metabolic process
FP497_RS16810	COG2169	Transcriptional regulator
FP497_RS16815	COG1982	Orn Lys Arg decarboxylase major
FP497_RS16820	COG2207	Transcriptional regulator
FP497_RS16825	COG0531	amino acid
FP497_RS16830	COG2194	sulfuric ester hydrolase activity
FP497_RS16835	COG0745	RESPONSE REGULATOR receiver
FP497_RS16840	COG0642	Histidine kinase
FP497_RS16850	COG0477	Major facilitator Superfamily
FP497_RS16860	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FP497_RS16865	COG2824	Alkylphosphonate utilization operon protein PhnA
FP497_RS16870	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FP497_RS16875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FP497_RS16880	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FP497_RS16890	COG2188	Transcriptional regulator
FP497_RS16895	COG3624	Phosphonate C-P lyase system protein PhnG
FP497_RS16900	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FP497_RS16905	COG3626	phosphonate metabolism
FP497_RS16910	COG3627	carbon phosphorus lyase activity
FP497_RS16915	COG4107	phosphonate C-P lyase system protein PhnK
FP497_RS16920	COG4778	phosphonate C-P lyase system protein PhnL
FP497_RS16925	COG3454	Phosphonate metabolism
FP497_RS16930	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FP497_RS16935	COG0456	acetyltransferase
FP497_RS16940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FP497_RS16950	COG0698	ribose 5-phosphate isomerase
FP497_RS16955	COG1737	Transcriptional regulator
FP497_RS16960	COG1879	ABC-type sugar transport system periplasmic component
FP497_RS16965	COG1129	ABC transporter
FP497_RS16970	COG1172	Belongs to the binding-protein-dependent transport system permease family
FP497_RS16975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FP497_RS16980	COG1940	carbohydrate kinase activity
FP497_RS16985	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FP497_RS16995	COG1566	PFAM secretion protein HlyD family protein
FP497_RS17000	COG1289	transmembrane transporter activity
FP497_RS17005	COG1538	Outer membrane efflux protein
FP497_RS17015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FP497_RS17020	COG1301	dicarboxylic acid transport
FP497_RS17025	COG4235	cytochrome complex assembly
FP497_RS17030	COG3088	subunit of a heme lyase
FP497_RS17035	COG1138	Cytochrome C-type biogenesis protein
FP497_RS17040	COG3301	Polysulphide reductase, NrfD
FP497_RS17045	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS17050	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FP497_RS17060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FP497_RS17065	COG3162	membrane
FP497_RS17075	COG1357	PFAM Pentapeptide repeats (8 copies)
FP497_RS17080	COG0025	NhaP-type Na H and K H
FP497_RS17085	COG2252	PERMEase
FP497_RS17090	COG0789	Transcriptional regulator
FP497_RS17095	COG2207	Transcriptional regulator
FP497_RS17100	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FP497_RS17110	COG0629	single-stranded DNA binding
FP497_RS17115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FP497_RS17120	COG2315	Protein conserved in bacteria
FP497_RS17125	COG0432	Pfam Uncharacterised protein family UPF0047
FP497_RS17130	COG3700	Belongs to the class B bacterial acid phosphatase family
FP497_RS17140	COG1448	Aminotransferase
FP497_RS17145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FP497_RS17150	COG0305	Participates in initiation and elongation during chromosome replication
FP497_RS17155	COG0604	alcohol dehydrogenase
FP497_RS17165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FP497_RS17180	COG0735	belongs to the Fur family
FP497_RS17185	COG3237	CsbD-like
FP497_RS17190	COG0534	Mate efflux family protein
FP497_RS17200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FP497_RS17235	COG3842	ATPase activity
FP497_RS17240	COG2182	Extracellular solute-binding protein
FP497_RS17245	COG1175	transmembrane transport
FP497_RS17250	COG3833	ABC-type maltose transport systems, permease component
FP497_RS17255	COG2814	Major facilitator Superfamily
FP497_RS17255	COG0477	Major facilitator Superfamily
FP497_RS17270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FP497_RS17295	COG0527	aspartate kinase activity
FP497_RS17305	COG1187	pseudouridine synthase activity
FP497_RS17315	COG1283	sodium-dependent phosphate transmembrane transporter activity
FP497_RS17320	COG1410	methionine synthase
FP497_RS17320	COG0646	methionine synthase
FP497_RS17325	COG1414	Transcriptional regulator
FP497_RS17340	COG2224	Isocitrate lyase
FP497_RS17345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FP497_RS17355	COG0456	acetyltransferase
FP497_RS17390	COG0151	Belongs to the GarS family
FP497_RS17395	COG2204	response regulator
FP497_RS17400	COG4191	Histidine kinase
FP497_RS17405	COG3678	ATP-independent chaperone mediated protein folding
FP497_RS17420	COG3068	Protein conserved in bacteria
FP497_RS17455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FP497_RS17460	COG2104	thiamine diphosphate biosynthetic process
FP497_RS17470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FP497_RS17510	COG0250	Participates in transcription elongation, termination and antitermination
FP497_RS17515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FP497_RS17550	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FP497_RS17550	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FP497_RS17555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FP497_RS17590	COG4206	TonB-dependent receptor
FP497_RS17605	COG1309	transcriptional regulator
FP497_RS17615	COG0583	DNA-binding transcription factor activity
FP497_RS17630	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FP497_RS17645	COG2194	sulfuric ester hydrolase activity
FP497_RS17650	COG2207	Transcriptional regulator
FP497_RS17655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS17660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FP497_RS17665	COG1882	Formate acetyltransferase
FP497_RS17670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS17675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS17680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS17680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FP497_RS17680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS17685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FP497_RS17690	COG0371	Dehydrogenase
FP497_RS17695	COG3738	Protein conserved in bacteria
FP497_RS17700	COG0697	spore germination
FP497_RS17710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FP497_RS17715	COG0527	aspartate kinase activity
FP497_RS17715	COG0460	homoserine dehydrogenase
FP497_RS17720	COG0626	cystathionine gamma-synthase activity
FP497_RS17730	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FP497_RS17740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FP497_RS17745	COG1609	Transcriptional regulator
FP497_RS17750	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FP497_RS17765	COG1575	Belongs to the MenA family. Type 1 subfamily
FP497_RS17780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FP497_RS17790	COG1494	fructose-1,6-bisphosphatase
FP497_RS17795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FP497_RS17800	COG0589	response to stress
FP497_RS17805	COG3691	Protein conserved in bacteria
FP497_RS17810	COG3152	Membrane
FP497_RS17830	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FP497_RS17845	COG3678	ATP-independent chaperone mediated protein folding
FP497_RS17850	COG0745	RESPONSE REGULATOR receiver
FP497_RS17855	COG2205	protein histidine kinase activity
FP497_RS17860	COG2258	MOSC domain
FP497_RS17870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FP497_RS17910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS17915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS17915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FP497_RS17920	COG1363	Peptidase, m42
FP497_RS17925	COG3711	transcriptional antiterminator
FP497_RS17925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FP497_RS17945	COG0437	4 iron, 4 sulfur cluster binding
FP497_RS17950	COG2864	formate dehydrogenase
FP497_RS17960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FP497_RS17965	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FP497_RS17970	COG0456	acetyltransferase
FP497_RS17985	COG1011	Hydrolase
FP497_RS17990	COG1349	DNA-binding transcription factor activity
FP497_RS17995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS18000	COG2084	Dehydrogenase
FP497_RS18005	COG3684	Belongs to the aldolase LacD family
FP497_RS18010	COG2942	2-epimerase
FP497_RS18015	COG2017	converts alpha-aldose to the beta-anomer
FP497_RS18020	COG1501	Belongs to the glycosyl hydrolase 31 family
FP497_RS18025	COG2211	Major facilitator Superfamily
FP497_RS18030	COG2211	Major facilitator Superfamily
FP497_RS18035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FP497_RS18040	COG2271	Major facilitator Superfamily
FP497_RS18045	COG1082	Xylose isomerase domain protein TIM barrel
FP497_RS18050	COG2188	Transcriptional regulator
FP497_RS18055	COG1217	gtp-binding protein TYPA
FP497_RS18060	COG0174	glutamine synthetase
FP497_RS18065	COG3852	Histidine kinase
FP497_RS18070	COG2204	response regulator
FP497_RS18080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FP497_RS18095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FP497_RS18095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FP497_RS18105	COG0204	Acyl-transferase
FP497_RS18110	COG5339	Protein conserved in bacteria
FP497_RS18115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FP497_RS18120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FP497_RS18125	COG3084	Protein conserved in bacteria
FP497_RS18130	COG0746	molybdenum cofactor guanylyltransferase activity
FP497_RS18135	COG1763	Mo-molybdopterin cofactor biosynthetic process
FP497_RS18170	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FP497_RS18175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FP497_RS18180	COG1739	Uncharacterized protein family UPF0029
FP497_RS18195	COG0183	Belongs to the thiolase family
FP497_RS18200	COG0543	2 iron, 2 sulfur cluster binding
FP497_RS18205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FP497_RS18210	COG0250	Participates in transcription elongation, termination and antitermination
FP497_RS18215	COG0084	hydrolase, TatD family'
FP497_RS18220	COG0805	protein transport
FP497_RS18225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FP497_RS18230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FP497_RS18240	COG3165	ubiquinone biosynthetic process from chorismate
FP497_RS18250	COG1322	Protein conserved in bacteria
FP497_RS18255	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FP497_RS18260	COG0412	Dienelactone hydrolase
FP497_RS18270	COG0583	DNA-binding transcription factor activity
FP497_RS18275	COG0697	spore germination
FP497_RS18280	COG0561	phosphatase activity
FP497_RS18285	COG2267	carboxylic ester hydrolase activity
FP497_RS18290	COG1280	lysine exporter protein (LysE YggA)
FP497_RS18295	COG1280	lysine exporter protein (LysE YggA)
FP497_RS18300	COG0514	ATP-dependent DNA helicase (RecQ)
FP497_RS18305	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FP497_RS18310	COG2050	protein possibly involved in aromatic compounds catabolism
FP497_RS18315	COG2962	Rard protein
FP497_RS18330	COG0598	Magnesium transport protein CorA
FP497_RS18335	COG3698	Phosphodiester glycosidase
FP497_RS18340	COG0210	DNA helicase
FP497_RS18345	COG1011	Hydrolase
FP497_RS18355	COG3159	Protein conserved in bacteria
FP497_RS18365	COG5567	small periplasmic lipoprotein
FP497_RS18380	COG3072	Adenylate cyclase
FP497_RS18390	COG1587	Uroporphyrinogen-III synthase
FP497_RS18395	COG2959	enzyme of heme biosynthesis
FP497_RS18400	COG3071	HemY protein
FP497_RS18405	COG3119	arylsulfatase activity
FP497_RS18410	COG0641	radical SAM
FP497_RS18435	COG1113	amino acid transport
FP497_RS18455	COG2244	polysaccharide biosynthetic process
FP497_RS18460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FP497_RS18465	COG0456	acetyltransferase
FP497_RS18470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FP497_RS18475	COG1088	dTDP-glucose 4,6-dehydratase activity
FP497_RS18480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FP497_RS18485	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FP497_RS18490	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FP497_RS18495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FP497_RS18500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FP497_RS18510	COG3118	belongs to the thioredoxin family
FP497_RS18525	COG0210	DNA helicase
FP497_RS18535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FP497_RS18545	COG0583	DNA-binding transcription factor activity
FP497_RS18550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FP497_RS18560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FP497_RS18565	COG3978	acetolactate synthase activity
FP497_RS18585	COG0606	chelatase, subunit chli
FP497_RS18590	COG3085	chromosome segregation
FP497_RS18630	COG2186	Transcriptional regulator
FP497_RS18635	COG0477	Major facilitator Superfamily
FP497_RS18640	COG1609	Transcriptional regulator
FP497_RS18645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FP497_RS18650	COG1879	ABC-type sugar transport system periplasmic component
FP497_RS18655	COG1172	Belongs to the binding-protein-dependent transport system permease family
FP497_RS18660	COG1129	ABC transporter
FP497_RS18690	COG1522	sequence-specific DNA binding
FP497_RS18695	COG0716	FMN binding
FP497_RS18710	COG3312	ion transport
FP497_RS18760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FP497_RS18765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FP497_RS18770	COG0573	inorganic phosphate transmembrane transporter activity
FP497_RS18775	COG0581	inorganic phosphate transmembrane transporter activity
FP497_RS18780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FP497_RS18785	COG0704	Plays a role in the regulation of phosphate uptake
FP497_RS18790	COG3711	transcriptional antiterminator
FP497_RS18795	COG2190	(PTS) system
FP497_RS18795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FP497_RS18795	COG1263	PTS System
FP497_RS18800	COG2723	6-phospho-beta-galactosidase activity
FP497_RS18810	COG2382	esterase
FP497_RS18815	COG0363	glucosamine-6-phosphate deaminase activity
FP497_RS18820	COG3196	Protein conserved in bacteria
FP497_RS18830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FP497_RS18835	COG2252	PERMEase
FP497_RS18840	COG0431	NADPH-dependent FMN reductase
FP497_RS18845	COG2091	lysine biosynthetic process via aminoadipic acid
FP497_RS18860	COG0814	amino acid