RG49_RS24940 6f9357bdbf7b5808d64dd5da6f039ae7 478 Pfam PF01050 Mannose-6-phosphate isomerase 323 473 1.1E-74 T 10-03-2017 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 RG49_RS24940 6f9357bdbf7b5808d64dd5da6f039ae7 478 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 6 477 7.2E-245 T 10-03-2017 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 RG49_RS24940 6f9357bdbf7b5808d64dd5da6f039ae7 478 Gene3D G3DSA:3.90.550.10 4 279 3.4E-102 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS24940 6f9357bdbf7b5808d64dd5da6f039ae7 478 Pfam PF00483 Nucleotidyl transferase 8 295 4.1E-80 T 10-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 RG49_RS24940 6f9357bdbf7b5808d64dd5da6f039ae7 478 SUPERFAMILY SSF51182 193 477 1.36E-88 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS24940 6f9357bdbf7b5808d64dd5da6f039ae7 478 SUPERFAMILY SSF53448 6 290 2.82E-74 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS24940 6f9357bdbf7b5808d64dd5da6f039ae7 478 Gene3D G3DSA:2.60.120.10 365 477 4.0E-47 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 Pfam PF00005 ABC transporter 17 178 2.5E-22 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 Pfam PF00005 ABC transporter 328 459 2.5E-25 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 SMART SM00382 337 506 2.3E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 SMART SM00382 26 223 2.4E-15 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 Pfam PF12848 ABC transporter 217 296 1.1E-28 T 10-03-2017 IPR032781 ABC-transporter extension domain RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 SUPERFAMILY SSF52540 295 516 5.75E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 Gene3D G3DSA:3.40.50.300 1 265 4.2E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 Gene3D G3DSA:3.40.50.300 310 538 7.6E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 SUPERFAMILY SSF52540 119 253 3.66E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17835 ba5c462cef0b296fac2ec3a842557184 637 SUPERFAMILY SSF52540 2 92 3.66E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 234 251 1.6E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 1.6E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 1.6E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 262 281 1.6E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 95 117 1.6E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 150 172 1.6E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 Pfam PF00267 Gram-negative porin 27 351 5.9E-151 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 1.9E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 152 163 1.9E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 228 240 1.9E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 306 323 1.9E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 95 105 1.9E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS10470 452448727b2c894066601a1370c6f052 351 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 306 322 - T 10-03-2017 IPR013793 Porin, Gram-negative type, conserved site RG49_RS10470 452448727b2c894066601a1370c6f052 351 SUPERFAMILY SSF56935 22 351 5.8E-80 T 10-03-2017 RG49_RS10470 452448727b2c894066601a1370c6f052 351 Gene3D G3DSA:2.40.160.10 22 351 8.1E-107 T 10-03-2017 IPR023614 Porin domain RG49_RS18620 f8eabdac91826090bfcf6a2066a5dd80 163 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 13 155 1.0E-36 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS18620 f8eabdac91826090bfcf6a2066a5dd80 163 Gene3D G3DSA:3.40.930.10 3 157 9.8E-48 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS18620 f8eabdac91826090bfcf6a2066a5dd80 163 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 9 155 4.4E-63 T 10-03-2017 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 RG49_RS18620 f8eabdac91826090bfcf6a2066a5dd80 163 SUPERFAMILY SSF55804 9 155 2.22E-42 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS18620 f8eabdac91826090bfcf6a2066a5dd80 163 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 58 74 - T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS16270 fdb414f4e30b434e0188c503edab33a3 338 Pfam PF08437 Glycosyl transferase family 8 C-terminal 278 334 2.1E-21 T 10-03-2017 IPR013645 Glycosyl transferase, family 8, C-terminal GO:0008918|GO:0009103 RG49_RS16270 fdb414f4e30b434e0188c503edab33a3 338 Pfam PF01501 Glycosyl transferase family 8 29 276 2.8E-57 T 10-03-2017 IPR002495 Glycosyl transferase, family 8 GO:0016757 RG49_RS16270 fdb414f4e30b434e0188c503edab33a3 338 SUPERFAMILY SSF53448 29 295 1.74E-65 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS16270 fdb414f4e30b434e0188c503edab33a3 338 Gene3D G3DSA:3.90.550.10 28 297 8.0E-68 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 Gene3D G3DSA:3.50.50.60 6 257 9.5E-39 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 4.8E-8 T 10-03-2017 RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 4.8E-8 T 10-03-2017 RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.8E-8 T 10-03-2017 RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 SUPERFAMILY SSF51905 4 183 7.79E-43 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 SUPERFAMILY SSF51905 283 366 7.79E-43 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 Pfam PF01494 FAD binding domain 7 189 3.9E-11 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS11650 a87c39e41931e84f94d7b94331865e2a 428 SUPERFAMILY SSF54373 181 283 6.67E-23 T 10-03-2017 RG49_RS05110 cb0f28a18101758115b2826cf1735e8f 341 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 3 332 48.718 T 10-03-2017 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 RG49_RS05110 cb0f28a18101758115b2826cf1735e8f 341 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 7 318 3.9E-102 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS05110 cb0f28a18101758115b2826cf1735e8f 341 Gene3D G3DSA:3.20.20.300 3 328 9.2E-97 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS05110 cb0f28a18101758115b2826cf1735e8f 341 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 234 251 - T 10-03-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 RG49_RS05110 cb0f28a18101758115b2826cf1735e8f 341 SUPERFAMILY SSF51445 3 316 6.84E-86 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS06865 697ba6368fc620b5775e2dec36caae23 321 SUPERFAMILY SSF56235 4 309 4.89E-100 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS06865 697ba6368fc620b5775e2dec36caae23 321 Pfam PF01112 Asparaginase 5 311 1.4E-120 T 10-03-2017 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 SMART SM00487 75 259 5.0E-27 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 Pfam PF00270 DEAD/DEAH box helicase 85 233 6.9E-6 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 SMART SM00490 304 404 1.0E-15 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 SUPERFAMILY SSF52540 74 601 3.61E-111 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 Pfam PF04408 Helicase associated domain (HA2) 466 557 4.5E-17 T 10-03-2017 IPR007502 Helicase-associated domain GO:0004386 RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 Gene3D G3DSA:3.40.50.300 77 233 3.8E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 Pfam PF11898 Domain of unknown function (DUF3418) 713 1297 1.2E-237 T 10-03-2017 IPR024590 RNA helicase HrpA, C-terminal RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 SMART SM00382 92 384 6.0E-5 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 SMART SM00847 464 559 1.1E-37 T 10-03-2017 IPR007502 Helicase-associated domain GO:0004386 RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 599 698 1.2E-16 T 10-03-2017 IPR011709 Domain of unknown function DUF1605 RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 13 1297 0.0 T 10-03-2017 IPR010222 RNA helicase HrpA GO:0004004 RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 Pfam PF00271 Helicase conserved C-terminal domain 284 403 5.2E-11 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS03360 dafe55cfcf566dcee4325859fc5a5338 1300 Gene3D G3DSA:3.40.50.300 271 416 4.6E-13 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 435 535 1.1E-17 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Gene3D G3DSA:1.10.287.130 329 387 1.3E-23 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 331 387 5.9E-12 T 10-03-2017 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 SUPERFAMILY SSF55890 338 465 1.57E-16 T 10-03-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 SUPERFAMILY SSF55874 433 535 5.5E-29 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 SMART SM00091 222 288 7.4E-6 T 10-03-2017 IPR000014 PAS domain RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 SMART SM00387 430 538 1.8E-24 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 497 1.3E-10 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 516 1.3E-10 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 535 1.3E-10 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 483 1.3E-10 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Pfam PF00989 PAS fold 222 323 4.4E-14 T 10-03-2017 IPR013767 PAS fold GO:0006355 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Gene3D G3DSA:3.30.565.10 416 535 1.4E-28 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 SUPERFAMILY SSF55785 222 323 7.04E-7 T 10-03-2017 IPR000014 PAS domain RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 SUPERFAMILY SSF103190 46 179 2.83E-41 T 10-03-2017 IPR029151 Periplasmic sensor domain-like RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Pfam PF17203 Single cache domain 3 47 179 7.9E-22 T 10-03-2017 IPR033463 Single cache domain 3 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Gene3D G3DSA:3.30.450.20 222 328 3.2E-12 T 10-03-2017 RG49_RS13320 13a046f26bd163bd6fcd8918b2626f8a 543 Gene3D G3DSA:3.30.450.20 41 179 9.2E-52 T 10-03-2017 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 7 153 1.8E-43 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 PRINTS PR00446 Hydrogen uptake protein signature 6 18 2.0E-30 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 PRINTS PR00446 Hydrogen uptake protein signature 18 29 2.0E-30 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 PRINTS PR00446 Hydrogen uptake protein signature 38 55 2.0E-30 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 PRINTS PR00446 Hydrogen uptake protein signature 70 86 2.0E-30 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 PRINTS PR00446 Hydrogen uptake protein signature 59 69 2.0E-30 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 Pfam PF01750 Hydrogenase maturation protease 23 151 1.7E-40 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 Gene3D G3DSA:3.40.50.1450 5 164 1.8E-49 T 10-03-2017 IPR023430 Peptidase HybD-like domain RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 SUPERFAMILY SSF53163 5 163 2.17E-43 T 10-03-2017 IPR023430 Peptidase HybD-like domain RG49_RS05835 5952a411eac57271b825b8d39b72bef0 195 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 6 157 4.3E-61 T 10-03-2017 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 Pfam PF04545 Sigma-70, region 4 185 233 6.7E-17 T 10-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 Gene3D G3DSA:1.10.10.10 173 238 8.0E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 Gene3D G3DSA:1.10.10.10 88 135 7.5E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 SUPERFAMILY SSF88946 5 88 3.61E-23 T 10-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 Pfam PF04542 Sigma-70 region 2 16 88 2.1E-16 T 10-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 Gene3D G3DSA:1.10.601.10 11 80 1.1E-14 T 10-03-2017 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 236 1.1E-32 T 10-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 PRINTS PR00046 Major sigma-70 factor signature 67 75 2.6E-13 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 PRINTS PR00046 Major sigma-70 factor signature 221 232 2.6E-13 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 PRINTS PR00046 Major sigma-70 factor signature 189 201 2.6E-13 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 PRINTS PR00046 Major sigma-70 factor signature 43 56 2.6E-13 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 PRINTS PR00046 Major sigma-70 factor signature 206 221 2.6E-13 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 SUPERFAMILY SSF88659 160 237 1.87E-20 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 SUPERFAMILY SSF88659 89 156 5.67E-17 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 43 56 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 5 239 64.511 T 10-03-2017 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 16 236 4.4E-88 T 10-03-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 Pfam PF04539 Sigma-70 region 3 97 166 5.6E-20 T 10-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS00290 c20fe62dfd86825e63dc84ddc671c884 239 PIRSF PIRSF000770 1 238 9.1E-43 T 10-03-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 RG49_RS05050 66775599b6932e6e8693e49d7f6499dd 233 Pfam PF00005 ABC transporter 25 173 1.2E-36 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS05050 66775599b6932e6e8693e49d7f6499dd 233 SUPERFAMILY SSF52540 5 224 2.52E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05050 66775599b6932e6e8693e49d7f6499dd 233 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS05050 66775599b6932e6e8693e49d7f6499dd 233 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 5 224 1.8E-112 T 10-03-2017 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 RG49_RS05050 66775599b6932e6e8693e49d7f6499dd 233 SMART SM00382 34 222 6.6E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS05050 66775599b6932e6e8693e49d7f6499dd 233 Gene3D G3DSA:3.40.50.300 5 226 9.4E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00790 ddfee4bbcad9bf0a12cc2fa6ce5da750 165 SMART SM00065 9 161 3.6E-15 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS00790 ddfee4bbcad9bf0a12cc2fa6ce5da750 165 SUPERFAMILY SSF55781 2 148 2.4E-42 T 10-03-2017 IPR029016 GAF domain-like RG49_RS00790 ddfee4bbcad9bf0a12cc2fa6ce5da750 165 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 90 107 - T 10-03-2017 IPR000614 Free Met sulfoxide reductase conserved site RG49_RS00790 ddfee4bbcad9bf0a12cc2fa6ce5da750 165 Pfam PF13185 GAF domain 37 151 3.3E-12 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS00790 ddfee4bbcad9bf0a12cc2fa6ce5da750 165 Gene3D G3DSA:3.30.450.40 2 151 3.1E-51 T 10-03-2017 IPR029016 GAF domain-like RG49_RS17950 a2ec8e0d0f617aaedd14a57a2e74a2af 195 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 1.9E-8 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS17950 a2ec8e0d0f617aaedd14a57a2e74a2af 195 Gene3D G3DSA:3.10.610.10 39 131 8.3E-8 T 10-03-2017 RG49_RS17950 a2ec8e0d0f617aaedd14a57a2e74a2af 195 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS17950 a2ec8e0d0f617aaedd14a57a2e74a2af 195 SUPERFAMILY SSF54523 40 176 6.8E-22 T 10-03-2017 RG49_RS17950 a2ec8e0d0f617aaedd14a57a2e74a2af 195 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 3 26 9.8E-9 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS12335 192281f395688aaf472974d89a211687 392 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 23 380 1.1E-134 T 10-03-2017 IPR010645 Uncharacterised MFS-type transporter YbfB RG49_RS12335 192281f395688aaf472974d89a211687 392 Gene3D G3DSA:1.20.1250.20 17 197 2.4E-8 T 10-03-2017 RG49_RS12335 192281f395688aaf472974d89a211687 392 Gene3D G3DSA:1.20.1250.20 212 380 2.1E-14 T 10-03-2017 RG49_RS12335 192281f395688aaf472974d89a211687 392 SUPERFAMILY SSF103473 13 381 1.31E-28 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS16950 231dd8666a5a46d071509482027df3cd 274 SUPERFAMILY SSF46689 193 243 1.08E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16950 231dd8666a5a46d071509482027df3cd 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 194 236 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS16950 231dd8666a5a46d071509482027df3cd 274 Pfam PF12833 Helix-turn-helix domain 164 242 8.5E-16 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS16950 231dd8666a5a46d071509482027df3cd 274 SMART SM00342 158 240 1.8E-31 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS16950 231dd8666a5a46d071509482027df3cd 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 209 224 1.4E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS16950 231dd8666a5a46d071509482027df3cd 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 240 1.4E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS16950 231dd8666a5a46d071509482027df3cd 274 Gene3D G3DSA:1.10.10.60 193 243 2.8E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS17900 329dd917b7479daf246d50f2cdcec458 156 PIRSF PIRSF002122 3 156 1.5E-63 T 10-03-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 RG49_RS17900 329dd917b7479daf246d50f2cdcec458 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 10-03-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17900 329dd917b7479daf246d50f2cdcec458 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.1E-64 T 10-03-2017 IPR023798 Ribosomal protein S7 domain RG49_RS17900 329dd917b7479daf246d50f2cdcec458 156 SUPERFAMILY SSF47973 6 149 6.15E-60 T 10-03-2017 IPR023798 Ribosomal protein S7 domain RG49_RS17900 329dd917b7479daf246d50f2cdcec458 156 Gene3D G3DSA:1.10.455.10 8 156 2.9E-67 T 10-03-2017 IPR023798 Ribosomal protein S7 domain RG49_RS17900 329dd917b7479daf246d50f2cdcec458 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.173 T 10-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 RG49_RS17900 329dd917b7479daf246d50f2cdcec458 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.6E-71 T 10-03-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 RG49_RS14655 c0e068ab23a6c7d07365f41705a9471c 148 SUPERFAMILY SSF55804 3 144 6.41E-31 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS14655 c0e068ab23a6c7d07365f41705a9471c 148 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 49 65 - T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS14655 c0e068ab23a6c7d07365f41705a9471c 148 Gene3D G3DSA:3.40.930.10 4 144 4.3E-35 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS14655 c0e068ab23a6c7d07365f41705a9471c 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 144 4.1E-31 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS14655 c0e068ab23a6c7d07365f41705a9471c 148 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 4 130 9.9E-44 T 10-03-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 SUPERFAMILY SSF54211 1 162 2.2E-32 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 PRINTS PR00958 Homoserine kinase signature 97 112 3.7E-34 T 10-03-2017 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 PRINTS PR00958 Homoserine kinase signature 254 269 3.7E-34 T 10-03-2017 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 PRINTS PR00958 Homoserine kinase signature 9 24 3.7E-34 T 10-03-2017 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 PRINTS PR00958 Homoserine kinase signature 137 150 3.7E-34 T 10-03-2017 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 PRINTS PR00958 Homoserine kinase signature 175 192 3.7E-34 T 10-03-2017 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 Pfam PF00288 GHMP kinases N terminal domain 85 150 7.1E-14 T 10-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 Hamap MF_00384 Homoserine kinase [thrB]. 2 307 31.0 T 10-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 Gene3D G3DSA:3.30.70.890 169 298 6.3E-41 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 TIGRFAM TIGR00191 thrB: homoserine kinase 2 309 1.3E-122 T 10-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 SUPERFAMILY SSF55060 172 289 2.88E-33 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 Pfam PF08544 GHMP kinases C terminal 212 281 6.6E-10 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 PIRSF PIRSF000676 1 310 4.1E-87 T 10-03-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 Gene3D G3DSA:3.30.230.10 1 164 2.6E-51 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS11875 76c455e312bbc25a609543bc830a44a2 310 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 90 101 - T 10-03-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 RG49_RS25140 e1b90d9cdd851d1aafe09ff98143aef9 452 Pfam PF13520 Amino acid permease 57 409 8.8E-35 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS25140 e1b90d9cdd851d1aafe09ff98143aef9 452 PIRSF PIRSF006060 2 445 1.8E-71 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 Gene3D G3DSA:3.30.230.10 5 207 1.4E-78 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 Gene3D G3DSA:3.30.70.890 208 380 5.4E-62 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 10-03-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PIRSF PIRSF000530 1 382 2.4E-122 T 10-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 Pfam PF10509 Galactokinase galactose-binding signature 11 58 1.8E-21 T 10-03-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 Pfam PF00288 GHMP kinases N terminal domain 115 181 3.2E-14 T 10-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00959 Mevalonate kinase family signature 25 49 2.0E-46 T 10-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00959 Mevalonate kinase family signature 162 181 2.0E-46 T 10-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00959 Mevalonate kinase family signature 328 345 2.0E-46 T 10-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00959 Mevalonate kinase family signature 119 141 2.0E-46 T 10-03-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 Hamap MF_00246 Galactokinase [galK]. 25 381 45.87 T 10-03-2017 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 SUPERFAMILY SSF55060 205 380 5.12E-52 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00473 Galactokinase signature 263 277 5.0E-30 T 10-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00473 Galactokinase signature 27 45 5.0E-30 T 10-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00473 Galactokinase signature 92 103 5.0E-30 T 10-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 PRINTS PR00473 Galactokinase signature 112 130 5.0E-30 T 10-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 TIGRFAM TIGR00131 gal_kin: galactokinase 5 382 2.2E-176 T 10-03-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 ProSitePatterns PS00106 Galactokinase signature. 27 38 - T 10-03-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 SUPERFAMILY SSF54211 3 202 1.67E-63 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS07255 c3a5104c676445d8933210aa5391f2f8 382 Pfam PF08544 GHMP kinases C terminal 279 361 4.4E-13 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 150 299 1.8E-9 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 PIRSF PIRSF005303 1 322 3.2E-87 T 10-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 319 32.431 T 10-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 322 5.6E-120 T 10-03-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 SUPERFAMILY SSF55326 4 138 1.41E-34 T 10-03-2017 RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 Gene3D G3DSA:3.90.650.10 145 322 1.1E-54 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 138 4.8E-21 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 Gene3D G3DSA:3.30.1330.10 3 139 8.3E-46 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS09045 dad5c3404a7cbb501851087af9277516 325 SUPERFAMILY SSF56042 143 307 1.38E-40 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 Pfam PF12798 4Fe-4S binding domain 51 67 0.0076 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 Gene3D G3DSA:3.30.70.20 64 88 1.1E-17 T 10-03-2017 RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 Gene3D G3DSA:3.30.70.20 137 183 7.8E-16 T 10-03-2017 RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 Gene3D G3DSA:3.30.70.20 11 63 3.5E-9 T 10-03-2017 RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 Gene3D G3DSA:3.30.70.20 89 101 7.8E-16 T 10-03-2017 RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 Pfam PF00037 4Fe-4S binding domain 76 98 3.4E-9 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 SUPERFAMILY SSF54862 2 101 1.36E-37 T 10-03-2017 RG49_RS22750 ff6de324eb19da8ab9d10e372df3de29 205 SUPERFAMILY SSF54862 139 185 1.36E-37 T 10-03-2017 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 Pfam PF02378 Phosphotransferase system, EIIC 13 320 6.7E-85 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 Pfam PF00367 phosphotransferase system, EIIB 405 436 7.3E-14 T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 378 460 2.6E-25 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 SUPERFAMILY SSF55604 401 474 6.67E-21 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 414 431 - T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 Gene3D G3DSA:3.30.1360.60 399 474 5.8E-28 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 475 1.2E-235 T 10-03-2017 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 RG49_RS05140 bcf0eda5bf6c0577bd8206fa6c2906b2 477 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 52 331 1.5E-90 T 10-03-2017 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 Pfam PF00072 Response regulator receiver domain 4 115 7.5E-31 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 SUPERFAMILY SSF52172 3 141 1.99E-33 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 Gene3D G3DSA:3.40.50.2300 2 119 5.8E-35 T 10-03-2017 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 SMART SM00421 147 204 3.5E-19 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 3.1E-22 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 SMART SM00448 2 115 8.8E-32 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 9.0E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 9.0E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 9.0E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 SUPERFAMILY SSF46894 132 210 9.52E-20 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS00340 9ec8290c74dc4a449b1bd93924a2c50a 218 Gene3D G3DSA:1.10.10.10 120 211 4.1E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 SUPERFAMILY SSF54826 3 112 3.89E-33 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 SMART SM00922 130 223 2.7E-18 T 10-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 SUPERFAMILY SSF51604 116 310 4.19E-51 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 Gene3D G3DSA:3.20.20.120 117 319 6.3E-61 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 Gene3D G3DSA:3.30.390.10 1 103 2.6E-47 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 87 112 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 173 204 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 Pfam PF13378 Enolase C-terminal domain-like 133 318 1.6E-25 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS03915 f088bde994e5710a9914fd9272acb316 321 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 1 112 2.5E-32 T 10-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain RG49_RS14515 f6c700aae0873675089d290443b8a219 99 Gene3D G3DSA:3.30.70.860 23 99 5.0E-30 T 10-03-2017 RG49_RS14515 f6c700aae0873675089d290443b8a219 99 TIGRFAM TIGR00743 TIGR00743: conserved hypothetical protein 4 96 5.6E-39 T 10-03-2017 IPR005272 Conserved hypothetical protein CHP00743 RG49_RS14515 f6c700aae0873675089d290443b8a219 99 Pfam PF04175 Protein of unknown function (DUF406) 5 96 3.1E-29 T 10-03-2017 IPR005272 Conserved hypothetical protein CHP00743 RG49_RS24555 42f56e489167f808d0238f10719f137e 561 Gene3D G3DSA:3.30.450.40 244 363 3.6E-4 T 10-03-2017 IPR029016 GAF domain-like RG49_RS24555 42f56e489167f808d0238f10719f137e 561 Gene3D G3DSA:3.30.565.10 422 559 1.1E-12 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24555 42f56e489167f808d0238f10719f137e 561 SUPERFAMILY SSF55781 243 359 5.23E-8 T 10-03-2017 IPR029016 GAF domain-like RG49_RS24555 42f56e489167f808d0238f10719f137e 561 Pfam PF07694 5TMR of 5TMR-LYT 28 196 8.3E-57 T 10-03-2017 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 RG49_RS24555 42f56e489167f808d0238f10719f137e 561 Pfam PF06580 Histidine kinase 371 448 1.5E-25 T 10-03-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 RG49_RS24555 42f56e489167f808d0238f10719f137e 561 Pfam PF13492 GAF domain 243 355 3.2E-6 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS24555 42f56e489167f808d0238f10719f137e 561 SMART SM00065 218 365 4.9E-12 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS24555 42f56e489167f808d0238f10719f137e 561 SUPERFAMILY SSF55874 424 556 2.88E-13 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS21200 db6f51994b96e7d3bc259c8bbb8e6364 259 SMART SM00893 28 212 3.5E-5 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS21200 db6f51994b96e7d3bc259c8bbb8e6364 259 PIRSF PIRSF000090 1 258 1.6E-46 T 10-03-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 RG49_RS21200 db6f51994b96e7d3bc259c8bbb8e6364 259 Pfam PF01012 Electron transfer flavoprotein domain 47 214 1.5E-18 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS21200 db6f51994b96e7d3bc259c8bbb8e6364 259 SUPERFAMILY SSF52402 1 248 6.0E-36 T 10-03-2017 RG49_RS21200 db6f51994b96e7d3bc259c8bbb8e6364 259 Gene3D G3DSA:3.40.50.620 1 250 4.9E-44 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 SUPERFAMILY SSF52440 3 139 2.59E-36 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 Gene3D G3DSA:3.30.1490.20 157 223 9.0E-27 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 Gene3D G3DSA:3.40.50.20 1 129 5.4E-36 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 10-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 PIRSF PIRSF039102 1 359 1.7E-139 T 10-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 107 118 - T 10-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 Gene3D G3DSA:3.30.470.20 224 361 1.1E-52 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 350 4.0E-120 T 10-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 Pfam PF07478 D-ala D-ala ligase C-terminus 147 348 9.8E-83 T 10-03-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 SUPERFAMILY SSF56059 140 354 1.01E-60 T 10-03-2017 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 Pfam PF01820 D-ala D-ala ligase N-terminus 5 130 9.4E-31 T 10-03-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS09235 da971fe75f46b0e67d0f7a765e069a77 364 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 351 42.927 T 10-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS18065 7db5f0a9ed08d687fd023064e70bb876 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 10-03-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18065 7db5f0a9ed08d687fd023064e70bb876 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 9.5E-27 T 10-03-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18065 7db5f0a9ed08d687fd023064e70bb876 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.352 T 10-03-2017 IPR023036 Ribosomal protein S14, bacterial/plastid RG49_RS18065 7db5f0a9ed08d687fd023064e70bb876 101 SUPERFAMILY SSF57716 2 101 8.55E-38 T 10-03-2017 RG49_RS18065 7db5f0a9ed08d687fd023064e70bb876 101 Gene3D G3DSA:4.10.830.10 41 101 2.8E-31 T 10-03-2017 RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 Gene3D G3DSA:3.40.50.10370 376 473 5.3E-42 T 10-03-2017 IPR029503 Phosphotransferase system EIIB component, mannitol-specific GO:0009401|GO:0022872 RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 8 347 3.9E-192 T 10-03-2017 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 SUPERFAMILY SSF55804 496 634 1.2E-40 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 SUPERFAMILY SSF52794 377 466 6.8E-22 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 Pfam PF02378 Phosphotransferase system, EIIC 17 277 2.0E-20 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 Gene3D G3DSA:3.40.930.10 497 634 5.2E-44 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 379 453 2.8E-9 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 539 555 - T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS16430 faf86e27ecec86d8f8ab8b449c1508cc 637 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 498 634 8.0E-33 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS07890 0754593e315c348cebd3f7d40cdf821f 160 Pfam PF07295 Zinc-ribbon containing domain 14 157 3.5E-53 T 10-03-2017 IPR009912 Zinc-ribbon containing domain RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 Gene3D G3DSA:2.60.120.280 56 193 5.5E-7 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 SUPERFAMILY SSF46689 237 286 4.17E-8 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 Gene3D G3DSA:1.10.10.60 194 238 5.3E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 Pfam PF12833 Helix-turn-helix domain 207 284 7.9E-17 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 Pfam PF02311 AraC-like ligand binding domain 65 128 1.5E-6 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 Gene3D G3DSA:1.10.10.60 239 287 2.6E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 SMART SM00342 200 283 5.6E-26 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 237 279 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 SUPERFAMILY SSF51215 14 165 6.93E-12 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS15825 539474d1ee401e3b1774cadc8e562048 297 SUPERFAMILY SSF46689 184 234 2.11E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02010 61bb0a9fd2417332ac9d035321439df4 309 TIGRFAM TIGR02648 rep_term_tus: DNA replication terminus site-binding protein 10 308 7.0E-166 T 10-03-2017 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 RG49_RS02010 61bb0a9fd2417332ac9d035321439df4 309 Gene3D G3DSA:3.50.14.10 7 219 6.4E-87 T 10-03-2017 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 RG49_RS02010 61bb0a9fd2417332ac9d035321439df4 309 Gene3D G3DSA:3.50.14.10 236 281 3.2E-14 T 10-03-2017 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 RG49_RS02010 61bb0a9fd2417332ac9d035321439df4 309 Pfam PF05472 DNA replication terminus site-binding protein (Ter protein) 9 306 3.0E-137 T 10-03-2017 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 RG49_RS02010 61bb0a9fd2417332ac9d035321439df4 309 Hamap MF_00483 DNA replication terminus site-binding protein [tus]. 1 309 74.454 T 10-03-2017 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 RG49_RS02010 61bb0a9fd2417332ac9d035321439df4 309 SUPERFAMILY SSF56596 5 308 2.09E-128 T 10-03-2017 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 RG49_RS09025 a3f97f10bebcc599f65f6498301607e7 299 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 10-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 RG49_RS09025 a3f97f10bebcc599f65f6498301607e7 299 Gene3D G3DSA:1.10.600.10 2 295 6.5E-91 T 10-03-2017 IPR008949 Isoprenoid synthase domain RG49_RS09025 a3f97f10bebcc599f65f6498301607e7 299 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 10-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 RG49_RS09025 a3f97f10bebcc599f65f6498301607e7 299 SUPERFAMILY SSF48576 1 280 6.78E-88 T 10-03-2017 IPR008949 Isoprenoid synthase domain RG49_RS09025 a3f97f10bebcc599f65f6498301607e7 299 Pfam PF00348 Polyprenyl synthetase 34 271 1.8E-56 T 10-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 71 1.0E-13 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 Gene3D G3DSA:1.10.10.10 12 93 9.2E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 SUPERFAMILY SSF53850 100 298 1.28E-23 T 10-03-2017 RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 Gene3D G3DSA:3.40.190.10 206 264 1.3E-7 T 10-03-2017 RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 SUPERFAMILY SSF46785 12 94 4.59E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 1.3E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 1.3E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 1.3E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 Pfam PF03466 LysR substrate binding domain 99 297 2.4E-25 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS12365 67881ec9fd4c4ab2ca7d7a1226c2eaac 303 Gene3D G3DSA:3.40.190.10 99 205 1.2E-6 T 10-03-2017 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 Pfam PF02119 Flagellar P-ring protein 21 364 6.0E-138 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 161 179 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 36 51 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 21 36 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 251 263 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 121 139 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 82 101 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 187 205 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 56 71 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 PRINTS PR01010 Flagellar P-ring protein signature 104 121 7.8E-94 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS05245 67fb099c2e90e37fdbfe05d9d8b550b2 365 Hamap MF_00416 Flagellar P-ring protein [flgI]. 4 365 40.239 T 10-03-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 Pfam PF14697 4Fe-4S dicluster domain 110 163 1.3E-16 T 10-03-2017 RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 117 128 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 Pfam PF04060 Putative Fe-S cluster 44 76 1.4E-12 T 10-03-2017 IPR007202 4Fe-4S domain GO:0051536 RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 PIRSF PIRSF005784 3 191 2.4E-84 T 10-03-2017 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 Gene3D G3DSA:3.30.70.20 111 177 7.2E-17 T 10-03-2017 RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 SUPERFAMILY SSF54862 38 174 4.31E-29 T 10-03-2017 RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 1 191 1.1E-88 T 10-03-2017 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 RG49_RS01910 e931b23c42c5e9f893309e237936e6c3 192 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 4 185 43.307 T 10-03-2017 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 RG49_RS06355 0e5f444e5b1ca30691342a1817857003 648 Pfam PF02687 FtsX-like permease family 527 641 2.3E-20 T 10-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 RG49_RS06355 0e5f444e5b1ca30691342a1817857003 648 Gene3D G3DSA:3.40.50.300 2 223 5.5E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06355 0e5f444e5b1ca30691342a1817857003 648 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06355 0e5f444e5b1ca30691342a1817857003 648 Pfam PF12704 MacB-like periplasmic core domain 272 491 9.1E-41 T 10-03-2017 IPR025857 MacB-like periplasmic core domain RG49_RS06355 0e5f444e5b1ca30691342a1817857003 648 SMART SM00382 33 220 1.0E-15 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06355 0e5f444e5b1ca30691342a1817857003 648 SUPERFAMILY SSF52540 4 226 2.92E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06355 0e5f444e5b1ca30691342a1817857003 648 Pfam PF00005 ABC transporter 24 172 3.9E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS08200 f35d1a48e0a520813cf40f9a3fe89a10 377 SUPERFAMILY SSF160355 64 330 9.29E-84 T 10-03-2017 RG49_RS08200 f35d1a48e0a520813cf40f9a3fe89a10 377 Pfam PF02706 Chain length determinant protein 25 173 4.2E-25 T 10-03-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 RG49_RS08200 f35d1a48e0a520813cf40f9a3fe89a10 377 Gene3D G3DSA:1.10.287.210 215 317 5.9E-46 T 10-03-2017 RG49_RS08200 f35d1a48e0a520813cf40f9a3fe89a10 377 Gene3D G3DSA:3.30.1890.10 52 214 4.0E-68 T 10-03-2017 RG49_RS15490 a3cf07be5f8d3b12a0bea22ff43933a5 330 Gene3D G3DSA:3.30.930.10 2 326 1.4E-152 T 10-03-2017 RG49_RS15490 a3cf07be5f8d3b12a0bea22ff43933a5 330 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 1 330 46.06 T 10-03-2017 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 RG49_RS15490 a3cf07be5f8d3b12a0bea22ff43933a5 330 PIRSF PIRSF001555 1 329 1.2E-150 T 10-03-2017 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 RG49_RS15490 a3cf07be5f8d3b12a0bea22ff43933a5 330 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 1 330 5.0E-200 T 10-03-2017 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 RG49_RS15490 a3cf07be5f8d3b12a0bea22ff43933a5 330 SUPERFAMILY SSF55681 7 329 3.09E-98 T 10-03-2017 RG49_RS15490 a3cf07be5f8d3b12a0bea22ff43933a5 330 Pfam PF03590 Aspartate-ammonia ligase 9 244 2.8E-93 T 10-03-2017 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 SUPERFAMILY SSF55961 160 440 4.95E-63 T 10-03-2017 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 163 433 2.5E-47 T 10-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 Hamap MF_01648 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha [hcaE]. 1 453 102.353 T 10-03-2017 IPR020875 3-phenylpropionate/cinnamic acid dioxygenase, alpha subunit GO:0005506|GO:0008695|GO:0019439|GO:0055114 KEGG: 00360+1.14.12.19|MetaCyc: PWY-6690 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 Pfam PF00355 Rieske [2Fe-2S] domain 43 125 5.6E-22 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 Gene3D G3DSA:2.102.10.10 43 145 5.2E-20 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 SUPERFAMILY SSF50022 3 157 3.4E-50 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 Gene3D G3DSA:3.90.380.10 146 440 2.2E-109 T 10-03-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 184 206 1.2E-60 T 10-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 1.2E-60 T 10-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 1.2E-60 T 10-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 99 119 1.2E-60 T 10-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 143 169 1.2E-60 T 10-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 1.2E-60 T 10-03-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 RG49_RS22380 45265b1d220acf5e7a0c02795b2e3f92 453 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 85 108 - T 10-03-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 RG49_RS07270 8b4efabd0c5b0f60af7efd20fd31a750 350 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 1.0E-183 T 10-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 RG49_RS07270 8b4efabd0c5b0f60af7efd20fd31a750 350 PIRSF PIRSF001361 1 350 9.9E-168 T 10-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 RG49_RS07270 8b4efabd0c5b0f60af7efd20fd31a750 350 Gene3D G3DSA:3.20.20.70 9 349 5.5E-164 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS07270 8b4efabd0c5b0f60af7efd20fd31a750 350 Pfam PF00793 DAHP synthetase I family 38 338 6.2E-113 T 10-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS07270 8b4efabd0c5b0f60af7efd20fd31a750 350 SUPERFAMILY SSF51569 7 348 6.28E-141 T 10-03-2017 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 Pfam PF03952 Enolase, N-terminal domain 4 134 5.7E-59 T 10-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 ProSitePatterns PS00164 Enolase signature. 339 352 - T 10-03-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 Gene3D G3DSA:3.30.390.10 3 127 2.1E-55 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 Hamap MF_00318 Enolase [eno]. 2 416 44.545 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 SMART SM01192 143 430 1.3E-215 T 10-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 PIRSF PIRSF001400 1 430 4.0E-194 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 8.8E-207 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 Gene3D G3DSA:3.20.20.120 128 429 3.0E-138 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 SUPERFAMILY SSF54826 3 138 3.71E-57 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 SUPERFAMILY SSF51604 143 427 9.34E-129 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 SMART SM01193 4 134 2.6E-94 T 10-03-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 429 6.0E-143 T 10-03-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 PRINTS PR00148 Enolase signature 339 353 3.9E-44 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 PRINTS PR00148 Enolase signature 368 385 3.9E-44 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 PRINTS PR00148 Enolase signature 37 51 3.9E-44 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 PRINTS PR00148 Enolase signature 165 178 3.9E-44 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 PRINTS PR00148 Enolase signature 316 327 3.9E-44 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21155 d196eab62d33c61927f63166a310bad3 432 PRINTS PR00148 Enolase signature 107 123 3.9E-44 T 10-03-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS10665 bbb41d8d7ab89b3167d39190a6f39cd3 174 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 14 164 5.8E-28 T 10-03-2017 IPR017734 Type VI secretion system, lipoprotein SciN RG49_RS10665 bbb41d8d7ab89b3167d39190a6f39cd3 174 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 5 167 9.3E-40 T 10-03-2017 IPR017734 Type VI secretion system, lipoprotein SciN RG49_RS07695 fb5cad1bdf5c957282b288c2e61ba77c 148 SUPERFAMILY SSF46785 6 134 1.76E-45 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07695 fb5cad1bdf5c957282b288c2e61ba77c 148 Pfam PF01475 Ferric uptake regulator family 10 130 6.9E-49 T 10-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 RG49_RS07695 fb5cad1bdf5c957282b288c2e61ba77c 148 Gene3D G3DSA:1.10.10.10 3 82 5.5E-31 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 Pfam PF13247 4Fe-4S dicluster domain 47 97 2.0E-7 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 Gene3D G3DSA:3.30.70.20 87 155 8.9E-10 T 10-03-2017 RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 Gene3D G3DSA:3.30.70.20 56 86 1.0E-13 T 10-03-2017 RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 SUPERFAMILY SSF54862 136 182 1.2E-41 T 10-03-2017 RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 SUPERFAMILY SSF54862 2 101 1.2E-41 T 10-03-2017 RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 Gene3D G3DSA:3.30.70.20 156 189 6.7E-23 T 10-03-2017 RG49_RS21460 46919942ab2c5cf900615572f80057ac 203 Gene3D G3DSA:3.30.70.20 5 55 6.7E-23 T 10-03-2017 RG49_RS07845 46e53b6857ae3fab3b72ae86615a0091 309 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 10-03-2017 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 RG49_RS07845 46e53b6857ae3fab3b72ae86615a0091 309 Hamap MF_01431 Pyrimidine-specific ribonucleoside hydrolase RihA [rihA]. 1 309 81.529 T 10-03-2017 IPR022975 Pyrimidine-specific ribonucleoside hydrolase RihA GO:0005737|GO:0006206|GO:0008152|GO:0015949|GO:0016787|GO:0016798|GO:0045437 RG49_RS07845 46e53b6857ae3fab3b72ae86615a0091 309 SUPERFAMILY SSF53590 4 308 1.12E-107 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS07845 46e53b6857ae3fab3b72ae86615a0091 309 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 300 1.4E-77 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS07845 46e53b6857ae3fab3b72ae86615a0091 309 Gene3D G3DSA:3.90.245.10 4 308 9.8E-116 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 SMART SM00881 9 104 1.2E-24 T 10-03-2017 IPR003781 CoA-binding GO:0048037 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 SUPERFAMILY SSF56059 481 686 1.34E-27 T 10-03-2017 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Gene3D G3DSA:3.40.50.261 128 279 3.1E-24 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Gene3D G3DSA:3.40.50.261 280 439 1.7E-15 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 SUPERFAMILY SSF52210 125 286 9.42E-36 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Gene3D G3DSA:3.40.50.720 1 127 2.4E-34 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Gene3D G3DSA:3.30.470.20 488 589 7.7E-5 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Pfam PF13380 CoA binding domain 13 129 1.5E-21 T 10-03-2017 IPR003781 CoA-binding GO:0048037 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 SUPERFAMILY SSF51735 2 136 1.47E-32 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Pfam PF13549 ATP-grasp domain 472 694 9.5E-75 T 10-03-2017 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Gene3D G3DSA:3.40.630.30 718 877 4.7E-26 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Pfam PF00583 Acetyltransferase (GNAT) family 790 863 4.8E-10 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 SUPERFAMILY SSF52210 287 447 4.97E-38 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 147 280 2.3E-46 T 10-03-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain RG49_RS22115 db3e7c99a4483274f13e77a0ccdcc479 886 SUPERFAMILY SSF55729 707 866 4.88E-22 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS09905 63e339233f5ed524bd69b7ac7044ce57 123 Gene3D G3DSA:1.10.3720.10 10 113 2.2E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS09905 63e339233f5ed524bd69b7ac7044ce57 123 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 10 108 2.4E-11 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS09905 63e339233f5ed524bd69b7ac7044ce57 123 SUPERFAMILY SSF161098 10 108 2.75E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 209 277 8.1E-10 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 Gene3D G3DSA:2.30.42.10 207 296 8.9E-20 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 Gene3D G3DSA:2.30.42.10 96 195 1.1E-10 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 SMART SM00228 115 186 0.11 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 SMART SM00228 211 280 8.0E-12 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 450 4.4E-184 T 10-03-2017 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 Pfam PF02163 Peptidase family M50 11 438 1.9E-89 T 10-03-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 SUPERFAMILY SSF50156 86 194 1.58E-12 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS10935 d976d8d9918e87307e67da061135fb82 450 SUPERFAMILY SSF50156 196 291 1.24E-17 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 Pfam PF05593 RHS Repeat 588 624 1.9E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 Pfam PF05593 RHS Repeat 733 766 4.3E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 Pfam PF05593 RHS Repeat 630 665 1.6E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 Pfam PF05593 RHS Repeat 462 495 1.2E-7 T 10-03-2017 IPR031325 RHS repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1184 1260 1.4E-22 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 462 498 4.9E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 588 629 1.0E-9 T 10-03-2017 IPR006530 YD repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 422 457 6.3E-8 T 10-03-2017 IPR006530 YD repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 650 690 3.9E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 630 664 0.0013 T 10-03-2017 IPR006530 YD repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 609 640 3.4E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 549 584 3.7E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 PRINTS PR00394 RHS protein signature 1113 1132 8.8E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 PRINTS PR00394 RHS protein signature 1182 1197 8.8E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 PRINTS PR00394 RHS protein signature 1151 1171 8.8E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 PRINTS PR00394 RHS protein signature 1229 1248 8.8E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 PRINTS PR00394 RHS protein signature 1206 1226 8.8E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS10600 1761bd95f08ecfaf108637ef9be6f3c7 1260 Pfam PF03527 RHS protein 1158 1193 2.3E-12 T 10-03-2017 IPR001826 RHS protein RG49_RS04375 fb1b9639248c5e7e67eb5002d66c86e0 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.3E-38 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04375 fb1b9639248c5e7e67eb5002d66c86e0 306 SUPERFAMILY SSF161098 89 291 2.62E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04375 fb1b9639248c5e7e67eb5002d66c86e0 306 Gene3D G3DSA:1.10.3720.10 88 302 1.1E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 SUPERFAMILY SSF63380 227 446 2.77E-64 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Pfam PF00667 FAD binding domain 230 424 3.5E-27 T 10-03-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 10 599 1.2E-289 T 10-03-2017 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Hamap MF_01541 Sulfite reductase [NADPH] flavoprotein alpha-component [cysJ]. 2 599 53.165 T 10-03-2017 IPR029758 Sulphite reductase [NADPH] flavoprotein, alpha chain, Proteobacteria GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Gene3D G3DSA:1.20.990.10 281 383 4.7E-41 T 10-03-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Gene3D G3DSA:2.40.30.10 229 280 2.7E-40 T 10-03-2017 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Gene3D G3DSA:2.40.30.10 384 454 2.7E-40 T 10-03-2017 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 SUPERFAMILY SSF52343 444 599 1.96E-52 T 10-03-2017 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00369 Flavodoxin signature 169 188 5.0E-14 T 10-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00369 Flavodoxin signature 113 124 5.0E-14 T 10-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00369 Flavodoxin signature 145 155 5.0E-14 T 10-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00369 Flavodoxin signature 65 78 5.0E-14 T 10-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Gene3D G3DSA:3.40.50.360 56 211 1.8E-47 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 494 505 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 548 556 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 525 541 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 386 393 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 456 475 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 270 280 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 481 490 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 419 428 2.8E-30 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Pfam PF00258 Flavodoxin 66 196 4.1E-32 T 10-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 PIRSF PIRSF000207 1 599 2.8E-284 T 10-03-2017 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 SUPERFAMILY SSF52218 60 208 8.57E-44 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Pfam PF00175 Oxidoreductase NAD-binding domain 457 563 9.8E-23 T 10-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 RG49_RS21230 d6fe7aa56bcb42a1964bcba4362c6756 599 Gene3D G3DSA:3.40.50.80 455 599 2.1E-59 T 10-03-2017 RG49_RS15510 3d5b7f08a6fc40f28ad8d1157f889b71 207 PIRSF PIRSF003078 1 207 1.1E-70 T 10-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 RG49_RS15510 3d5b7f08a6fc40f28ad8d1157f889b71 207 Pfam PF02527 rRNA small subunit methyltransferase G 20 200 1.7E-68 T 10-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 RG49_RS15510 3d5b7f08a6fc40f28ad8d1157f889b71 207 Gene3D G3DSA:3.40.50.150 4 205 7.1E-75 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS15510 3d5b7f08a6fc40f28ad8d1157f889b71 207 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 13 201 28.973 T 10-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 RG49_RS15510 3d5b7f08a6fc40f28ad8d1157f889b71 207 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 203 5.3E-63 T 10-03-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 RG49_RS15510 3d5b7f08a6fc40f28ad8d1157f889b71 207 SUPERFAMILY SSF53335 4 204 1.69E-43 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS15830 2f255d2b1caefd12af40e5ea13c5d380 571 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 443 1.8E-125 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS15830 2f255d2b1caefd12af40e5ea13c5d380 571 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 160 185 - T 10-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS15830 2f255d2b1caefd12af40e5ea13c5d380 571 Pfam PF00474 Sodium:solute symporter family 35 442 1.4E-50 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS00465 10457d0c0a94dd8cb27f07f331deffdf 308 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 13 66 1.4E-19 T 10-03-2017 IPR025713 Motility protein B, N-terminal domain RG49_RS00465 10457d0c0a94dd8cb27f07f331deffdf 308 Pfam PF00691 OmpA family 160 257 1.8E-12 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS00465 10457d0c0a94dd8cb27f07f331deffdf 308 Gene3D G3DSA:3.30.1330.60 151 264 1.0E-15 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS00465 10457d0c0a94dd8cb27f07f331deffdf 308 SUPERFAMILY SSF103088 156 264 2.75E-18 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 SUPERFAMILY SSF75620 12 353 7.32E-138 T 10-03-2017 RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 Pfam PF03462 PCRF domain 13 203 2.5E-76 T 10-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 Gene3D G3DSA:1.20.58.410 6 93 1.8E-18 T 10-03-2017 RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 Gene3D G3DSA:3.30.160.20 215 288 1.6E-35 T 10-03-2017 IPR014720 Double-stranded RNA-binding domain RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 10-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 358 3.0E-177 T 10-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 Pfam PF00472 RF-1 domain 216 321 3.5E-41 T 10-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 SMART SM00937 63 178 6.8E-72 T 10-03-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 RG49_RS04575 ebe0a3fcfb3e5d36ef27b7a5954b597f 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 41.334 T 10-03-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 147 1.2E-25 T 10-03-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 SUPERFAMILY SSF54211 167 251 1.07E-31 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 SUPERFAMILY SSF56784 1 158 1.76E-40 T 10-03-2017 IPR023214 HAD-like domain RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 Pfam PF08645 Polynucleotide kinase 3 phosphatase 8 133 5.3E-6 T 10-03-2017 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 2 355 54.891 T 10-03-2017 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 144 8.1E-46 T 10-03-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 SUPERFAMILY SSF54211 252 342 1.15E-31 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 226 239 - T 10-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 167 355 37.396 T 10-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 319 331 - T 10-03-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 Gene3D G3DSA:3.30.230.40 258 355 2.3E-31 T 10-03-2017 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 Gene3D G3DSA:3.40.50.1000 1 171 1.3E-42 T 10-03-2017 IPR023214 HAD-like domain RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 3 162 2.9E-83 T 10-03-2017 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 196 337 7.8E-64 T 10-03-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 RG49_RS25090 d0fed768032705c6acde66f925051b8d 355 Gene3D G3DSA:3.30.230.40 172 253 3.0E-38 T 10-03-2017 RG49_RS12760 8c45f185b615ccfdadcba458da6cd960 176 Pfam PF00719 Inorganic pyrophosphatase 18 173 3.9E-55 T 10-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 RG49_RS12760 8c45f185b615ccfdadcba458da6cd960 176 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 10-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 RG49_RS12760 8c45f185b615ccfdadcba458da6cd960 176 SUPERFAMILY SSF50324 4 174 6.02E-68 T 10-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 RG49_RS12760 8c45f185b615ccfdadcba458da6cd960 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 37.626 T 10-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 RG49_RS12760 8c45f185b615ccfdadcba458da6cd960 176 Gene3D G3DSA:3.90.80.10 5 175 2.0E-62 T 10-03-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 RG49_RS08665 10982b4cd4282f028d3bed2daee0cfda 50 Pfam PF12035 Protein of unknown function (DUF3521) 1 28 1.5E-7 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 Gene3D G3DSA:3.40.50.20 1 69 1.0E-24 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 3 329 1.1E-117 T 10-03-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 Gene3D G3DSA:3.30.470.20 156 336 1.2E-60 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 SUPERFAMILY SSF51246 278 353 9.42E-21 T 10-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 SUPERFAMILY SSF56059 79 274 4.42E-59 T 10-03-2017 RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 Gene3D G3DSA:3.30.1490.20 94 154 1.4E-22 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 SUPERFAMILY SSF52440 2 76 7.63E-16 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 Pfam PF02222 ATP-grasp domain 88 254 2.3E-57 T 10-03-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type RG49_RS08470 54044f94bc75917bd942114e12e64b90 355 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 325 33.584 T 10-03-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 RG49_RS15755 29cb895295a5d43d42c07c5536ce3ee3 292 Pfam PF05035 2-keto-3-deoxy-galactonokinase 9 286 6.0E-97 T 10-03-2017 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 RG49_RS07505 225ab6496bd63862595a1bb554914683 242 Gene3D G3DSA:2.60.40.1070 148 234 4.9E-25 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS07505 225ab6496bd63862595a1bb554914683 242 PRINTS PR00969 Pili chaperone signature 68 89 2.4E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS07505 225ab6496bd63862595a1bb554914683 242 PRINTS PR00969 Pili chaperone signature 124 139 2.4E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS07505 225ab6496bd63862595a1bb554914683 242 PRINTS PR00969 Pili chaperone signature 98 115 2.4E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS07505 225ab6496bd63862595a1bb554914683 242 PRINTS PR00969 Pili chaperone signature 160 175 2.4E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS07505 225ab6496bd63862595a1bb554914683 242 PRINTS PR00969 Pili chaperone signature 22 31 2.4E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS07505 225ab6496bd63862595a1bb554914683 242 Gene3D G3DSA:2.60.40.360 22 142 1.1E-39 T 10-03-2017 IPR008962 PapD-like RG49_RS07505 225ab6496bd63862595a1bb554914683 242 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 97 114 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS07505 225ab6496bd63862595a1bb554914683 242 SUPERFAMILY SSF49584 149 233 4.45E-20 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS07505 225ab6496bd63862595a1bb554914683 242 SUPERFAMILY SSF49354 22 142 1.15E-35 T 10-03-2017 IPR008962 PapD-like RG49_RS07505 225ab6496bd63862595a1bb554914683 242 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 22 142 3.4E-34 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS07505 225ab6496bd63862595a1bb554914683 242 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 166 222 1.9E-12 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 Pfam PF13181 Tetratricopeptide repeat 747 776 0.046 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SUPERFAMILY SSF48452 736 812 2.31E-13 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SUPERFAMILY SSF48452 568 607 2.31E-13 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 Pfam PF13432 Tetratricopeptide repeat 542 602 2.4E-4 T 10-03-2017 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SUPERFAMILY SSF48452 484 625 1.47E-17 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 Gene3D G3DSA:1.25.40.10 482 640 2.0E-17 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 Gene3D G3DSA:1.25.40.10 736 814 1.1E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 Pfam PF17128 Domain of unknown function (DUF5107) 39 343 2.1E-68 T 10-03-2017 IPR033396 Domain of unknown function DUF5107 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 Gene3D G3DSA:1.25.40.10 896 1011 3.3E-4 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SUPERFAMILY SSF48452 892 1009 2.92E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SMART SM00028 778 812 170.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SMART SM00028 744 777 0.082 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SMART SM00028 495 528 92.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SMART SM00028 535 568 73.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS22325 c904e966a01583ebebe874c07d852c83 1093 SMART SM00028 569 602 0.015 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 Pfam PF07882 L-fucose isomerase, second N-terminal domain 175 354 3.0E-81 T 10-03-2017 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 SUPERFAMILY SSF50443 356 590 7.59E-129 T 10-03-2017 IPR004216 L-fucose/L-arabinose isomerase, C-terminal RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 Pfam PF07881 L-fucose isomerase, first N-terminal domain 7 174 1.4E-83 T 10-03-2017 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 SUPERFAMILY SSF53743 2 355 7.85E-156 T 10-03-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 Gene3D G3DSA:3.40.50.1070 4 175 1.3E-97 T 10-03-2017 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 Gene3D G3DSA:3.40.275.10 176 340 1.7E-80 T 10-03-2017 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 Gene3D G3DSA:3.20.14.10 341 590 2.2E-132 T 10-03-2017 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 TIGRFAM TIGR01089 fucI: L-fucose isomerase 5 590 0.0 T 10-03-2017 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 Hamap MF_01254 L-fucose isomerase [fucI]. 3 591 72.152 T 10-03-2017 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 RG49_RS21035 8be48c0b4f5abcc4f987fbefabcff969 591 Pfam PF02952 L-fucose isomerase, C-terminal domain 390 554 8.6E-55 T 10-03-2017 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 RG49_RS04305 6dd1d92415e620b86e62141ad0579296 212 Gene3D G3DSA:2.40.160.20 22 212 3.2E-73 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS04305 6dd1d92415e620b86e62141ad0579296 212 Pfam PF03922 OmpW family 23 212 3.1E-73 T 10-03-2017 IPR005618 Outer membrane protein, OmpW GO:0019867 RG49_RS04305 6dd1d92415e620b86e62141ad0579296 212 SUPERFAMILY SSF56925 28 212 8.37E-26 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:3.90.640.10 239 310 1.0E-10 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 616 45.738 T 10-03-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 615 4.8E-272 T 10-03-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:3.30.420.40 314 356 9.8E-32 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:3.30.420.40 201 238 9.8E-32 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Pfam PF00012 Hsp70 protein 22 600 8.7E-205 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 10-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 329 345 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 385 404 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 20 33 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 360 380 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 466 482 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 48 60 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 152 172 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 PRINTS PR00301 70kDa heat shock protein signature 211 221 2.9E-54 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:3.30.30.30 88 127 5.5E-10 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 SUPERFAMILY SSF53067 20 196 2.2E-49 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 10-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:3.30.420.40 20 87 1.7E-52 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:3.30.420.40 128 200 1.7E-52 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 SUPERFAMILY SSF53067 200 377 2.8E-53 T 10-03-2017 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 SUPERFAMILY SSF100934 504 615 3.92E-37 T 10-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 10-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:1.20.1270.10 529 615 1.4E-33 T 10-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 SUPERFAMILY SSF100920 384 535 4.58E-50 T 10-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 RG49_RS22440 d2746a20c66cfb1cdc9c1eb5b8feda3c 616 Gene3D G3DSA:2.60.34.10 387 528 6.2E-55 T 10-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 RG49_RS00435 6ae3aa47cfbf84cc40071d61134c4b48 266 Pfam PF02358 Trehalose-phosphatase 18 229 2.0E-56 T 10-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 RG49_RS00435 6ae3aa47cfbf84cc40071d61134c4b48 266 Gene3D G3DSA:3.40.50.1000 15 90 2.0E-44 T 10-03-2017 IPR023214 HAD-like domain RG49_RS00435 6ae3aa47cfbf84cc40071d61134c4b48 266 Gene3D G3DSA:3.40.50.1000 165 257 2.0E-44 T 10-03-2017 IPR023214 HAD-like domain RG49_RS00435 6ae3aa47cfbf84cc40071d61134c4b48 266 SUPERFAMILY SSF56784 17 243 2.07E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS00435 6ae3aa47cfbf84cc40071d61134c4b48 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 18 213 4.5E-21 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS00435 6ae3aa47cfbf84cc40071d61134c4b48 266 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 12 244 1.9E-92 T 10-03-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 RG49_RS13805 93fa29eb4f4d25c14ab2ab5e3612a356 69 PIRSF PIRSF039008 1 66 3.3E-31 T 10-03-2017 IPR026042 Stress response protein YjbJ RG49_RS13805 93fa29eb4f4d25c14ab2ab5e3612a356 69 Gene3D G3DSA:1.10.1470.10 1 67 1.1E-31 T 10-03-2017 IPR008462 CsbD-like RG49_RS13805 93fa29eb4f4d25c14ab2ab5e3612a356 69 Pfam PF05532 CsbD-like 4 56 8.0E-22 T 10-03-2017 IPR008462 CsbD-like RG49_RS13805 93fa29eb4f4d25c14ab2ab5e3612a356 69 SUPERFAMILY SSF69047 1 69 9.29E-27 T 10-03-2017 IPR008462 CsbD-like RG49_RS12580 ebd46305b825ee934c2340d3d0707d31 360 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 358 2.5E-72 T 10-03-2017 IPR005495 Permease LptG/LptF-related GO:0016021 RG49_RS12580 ebd46305b825ee934c2340d3d0707d31 360 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 6 358 1.5E-137 T 10-03-2017 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 SUPERFAMILY SSF52540 252 480 3.24E-40 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 Gene3D G3DSA:3.40.50.300 254 467 1.5E-39 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 Gene3D G3DSA:3.40.50.300 10 228 6.9E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 SMART SM00382 28 219 1.9E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 SMART SM00382 285 479 1.1E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 SUPERFAMILY SSF52540 10 226 3.17E-36 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 Pfam PF00005 ABC transporter 276 429 2.5E-26 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS07240 cbe3f5ba45f669738336d39fe7a1a1b8 490 Pfam PF00005 ABC transporter 23 163 7.0E-18 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS19790 d90a1ebb127f654db3d4a7c56ce5df07 567 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 543 552 - T 10-03-2017 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 RG49_RS19790 d90a1ebb127f654db3d4a7c56ce5df07 567 Gene3D G3DSA:1.10.645.10 1 552 1.6E-210 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS19790 d90a1ebb127f654db3d4a7c56ce5df07 567 SUPERFAMILY SSF56762 1 552 2.75E-169 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS19790 d90a1ebb127f654db3d4a7c56ce5df07 567 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 10-03-2017 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 RG49_RS19790 d90a1ebb127f654db3d4a7c56ce5df07 567 Pfam PF00374 Nickel-dependent hydrogenase 39 552 5.5E-210 T 10-03-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 Gene3D G3DSA:3.30.470.30 128 244 1.1E-20 T 10-03-2017 RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 SMART SM00532 29 425 1.9E-138 T 10-03-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 Hamap MF_01587 DNA ligase B [ligB]. 3 558 52.141 T 10-03-2017 IPR020923 DNA ligase B GO:0003911|GO:0006259 RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 Gene3D G3DSA:1.10.287.610 26 70 2.6E-7 T 10-03-2017 RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 Gene3D G3DSA:2.40.50.140 310 381 2.2E-20 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 321 336 - T 10-03-2017 IPR033136 NAD-dependent DNA ligase, conserved site RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 SUPERFAMILY SSF47781 404 556 6.04E-18 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 SUPERFAMILY SSF56091 25 305 5.44E-66 T 10-03-2017 RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 SUPERFAMILY SSF50249 310 386 4.45E-17 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 124 153 - T 10-03-2017 IPR018239 NAD-dependent DNA ligase, active site RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 312 385 9.9E-19 T 10-03-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 RG49_RS16160 cce2618bcee96562c964ed9b740fb9fa 560 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 113 306 6.0E-23 T 10-03-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 RG49_RS14635 d05b85b9e712b703745e8b56d7e44768 419 Gene3D G3DSA:3.20.20.150 2 418 8.9E-229 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS14635 d05b85b9e712b703745e8b56d7e44768 419 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 9 418 0.0 T 10-03-2017 RG49_RS14635 d05b85b9e712b703745e8b56d7e44768 419 Pfam PF06134 L-rhamnose isomerase (RhaA) 3 418 7.5E-239 T 10-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 RG49_RS14635 d05b85b9e712b703745e8b56d7e44768 419 TIGRFAM TIGR01748 rhaA: L-rhamnose isomerase 5 418 2.8E-250 T 10-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 RG49_RS14635 d05b85b9e712b703745e8b56d7e44768 419 SUPERFAMILY SSF51658 4 418 2.73E-83 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS14635 d05b85b9e712b703745e8b56d7e44768 419 Hamap MF_00541 L-rhamnose isomerase [rhaA]. 1 419 278.93 T 10-03-2017 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Pfam PF00512 His Kinase A (phospho-acceptor) domain 711 777 1.1E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SMART SM00387 824 938 3.5E-32 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SMART SM00388 711 777 6.8E-20 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:3.40.190.10 381 463 3.7E-4 T 10-03-2017 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SUPERFAMILY SSF47384 695 778 2.94E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:3.40.50.2300 957 1062 1.2E-36 T 10-03-2017 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:1.20.120.160 1063 1193 2.0E-11 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SUPERFAMILY SSF53850 296 522 5.13E-32 T 10-03-2017 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:3.40.190.10 54 186 3.8E-11 T 10-03-2017 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SUPERFAMILY SSF52172 957 1086 7.83E-36 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SMART SM00062 57 279 5.4E-4 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SMART SM00062 303 522 1.4E-46 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Pfam PF00072 Response regulator receiver domain 961 1070 1.6E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SUPERFAMILY SSF55874 767 938 1.57E-39 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Pfam PF01627 Hpt domain 1104 1160 5.1E-5 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:1.10.287.130 710 772 1.1E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:3.30.565.10 779 940 2.5E-42 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SUPERFAMILY SSF47226 1053 1182 1.44E-15 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 825 937 3.9E-24 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SUPERFAMILY SSF53850 50 276 3.92E-23 T 10-03-2017 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 306 520 2.3E-24 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 74 276 8.0E-13 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SMART SM00448 959 1070 2.9E-34 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 SMART SM00073 1094 1193 3.5E-18 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:3.40.190.10 482 520 3.9E-14 T 10-03-2017 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 Gene3D G3DSA:3.40.190.10 300 380 3.9E-14 T 10-03-2017 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 865 879 1.7E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 898 916 1.7E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 883 893 1.7E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS23300 46ebed405403de3f0f489e6aef12b1ce 1197 PRINTS PR00344 Bacterial sensor protein C-terminal signature 922 935 1.7E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 364 383 - T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 48 5.7E-16 T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 455 462 - T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 474 9.4E-166 T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 PRINTS PR00045 Sigma-54 factor signature 186 203 2.0E-31 T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 PRINTS PR00045 Sigma-54 factor signature 376 388 2.0E-31 T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 PRINTS PR00045 Sigma-54 factor signature 450 468 2.0E-31 T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 PRINTS PR00045 Sigma-54 factor signature 392 403 2.0E-31 T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 Pfam PF04963 Sigma-54 factor, core binding domain 114 303 3.0E-62 T 10-03-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 Pfam PF04552 Sigma-54, DNA binding domain 317 475 1.0E-70 T 10-03-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding RG49_RS18630 cd22b32ea00575d7ed99e863217ced58 477 PIRSF PIRSF000774 1 477 2.4E-153 T 10-03-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 RG49_RS22940 3f1c9ee2c90589762a0d89496ed741d4 350 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 293 338 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS22940 3f1c9ee2c90589762a0d89496ed741d4 350 Pfam PF12833 Helix-turn-helix domain 262 342 4.6E-23 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS22940 3f1c9ee2c90589762a0d89496ed741d4 350 Gene3D G3DSA:1.10.10.60 237 295 6.9E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS22940 3f1c9ee2c90589762a0d89496ed741d4 350 SUPERFAMILY SSF46689 240 290 4.3E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS22940 3f1c9ee2c90589762a0d89496ed741d4 350 SMART SM00342 256 342 3.8E-22 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS23200 33b4c0cf74a0325ea1d3086af7ba8f90 321 SUPERFAMILY SSF53067 4 318 1.3E-64 T 10-03-2017 RG49_RS23200 33b4c0cf74a0325ea1d3086af7ba8f90 321 Gene3D G3DSA:3.40.367.20 100 299 5.5E-79 T 10-03-2017 RG49_RS23200 33b4c0cf74a0325ea1d3086af7ba8f90 321 Pfam PF02685 Glucokinase 6 315 4.0E-124 T 10-03-2017 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 RG49_RS23200 33b4c0cf74a0325ea1d3086af7ba8f90 321 TIGRFAM TIGR00749 glk: glucokinase 6 310 8.7E-157 T 10-03-2017 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 RG49_RS23200 33b4c0cf74a0325ea1d3086af7ba8f90 321 Hamap MF_00524 Glucokinase [glk]. 2 316 40.324 T 10-03-2017 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 RG49_RS18260 f8f870bc9dc4e733da3820702c79e5f4 341 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 253 1.4E-32 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS18260 f8f870bc9dc4e733da3820702c79e5f4 341 SUPERFAMILY SSF53850 27 256 4.92E-49 T 10-03-2017 RG49_RS18260 f8f870bc9dc4e733da3820702c79e5f4 341 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 59 72 - T 10-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 RG49_RS18260 f8f870bc9dc4e733da3820702c79e5f4 341 Gene3D G3DSA:3.40.190.10 33 127 9.6E-20 T 10-03-2017 RG49_RS18260 f8f870bc9dc4e733da3820702c79e5f4 341 Gene3D G3DSA:3.40.190.10 225 251 9.6E-20 T 10-03-2017 RG49_RS18260 f8f870bc9dc4e733da3820702c79e5f4 341 SMART SM00062 36 265 1.3E-61 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS18260 f8f870bc9dc4e733da3820702c79e5f4 341 Gene3D G3DSA:3.40.190.10 128 224 7.5E-16 T 10-03-2017 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 SUPERFAMILY SSF46689 222 325 1.93E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 222 231 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 Gene3D G3DSA:3.40.50.300 6 179 2.6E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 SMART SM00382 28 180 2.9E-10 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 Gene3D G3DSA:1.10.8.60 180 253 1.1E-21 T 10-03-2017 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 94 109 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 8 323 9.6E-162 T 10-03-2017 IPR014317 Transcription activator PspF RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 Gene3D G3DSA:1.10.10.60 277 325 3.0E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 289 306 6.1E-6 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 306 325 6.1E-6 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 Pfam PF02954 Bacterial regulatory protein, Fis family 286 322 5.0E-5 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 SUPERFAMILY SSF52540 9 250 1.27E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04025 1b9e56cbcef41086039e5b0acfff5edc 325 Pfam PF00158 Sigma-54 interaction domain 9 170 2.0E-62 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 TIGRFAM TIGR01083 nth: endonuclease III 4 194 1.5E-90 T 10-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 2.2E-20 T 10-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 Gene3D G3DSA:1.10.1670.10 123 208 1.4E-36 T 10-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 Gene3D G3DSA:1.10.340.30 22 122 2.2E-34 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 SMART SM00478 38 185 9.8E-55 T 10-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 SUPERFAMILY SSF48150 3 208 3.3E-74 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.662 T 10-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 10-03-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 10-03-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 SMART SM00525 186 206 1.4E-5 T 10-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 1.1E-4 T 10-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 Pfam PF00633 Helix-hairpin-helix motif 100 127 3.1E-7 T 10-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 RG49_RS01885 2e3946f18d148e9aa5d7104f4a7b2eeb 211 PIRSF PIRSF001435 1 210 2.5E-52 T 10-03-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 Gene3D G3DSA:3.40.50.1360 78 214 1.5E-8 T 10-03-2017 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 SMART SM01134 74 234 3.5E-51 T 10-03-2017 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 Gene3D G3DSA:1.10.10.10 1 53 4.7E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 Pfam PF00455 DeoR C terminal sensor domain 76 233 1.6E-44 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 1.5E-9 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 1.5E-9 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 SUPERFAMILY SSF100950 76 233 1.15E-27 T 10-03-2017 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 SUPERFAMILY SSF46785 4 59 2.34E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 SMART SM00420 5 57 1.4E-22 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21020 1c22e9428d5342ff7ce99f6d8c9c5ee3 243 Pfam PF08220 DeoR-like helix-turn-helix domain 5 60 2.1E-21 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS01915 681c6b4ad29902edac090fcde2cc95c7 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 2.4E-92 T 10-03-2017 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 RG49_RS01915 681c6b4ad29902edac090fcde2cc95c7 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 3.7E-60 T 10-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 RG49_RS01915 681c6b4ad29902edac090fcde2cc95c7 193 PIRSF PIRSF006102 1 193 8.7E-60 T 10-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 RG49_RS01915 681c6b4ad29902edac090fcde2cc95c7 193 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 26.541 T 10-03-2017 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Pfam PF00702 haloacid dehalogenase-like hydrolase 518 732 1.7E-49 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF56784 519 539 1.28E-57 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF56784 576 824 1.28E-57 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Gene3D G3DSA:3.40.1110.10 535 645 2.8E-18 T 10-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 ProSitePatterns PS01047 Heavy-metal-associated domain. 105 134 - T 10-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 233 827 7.6E-194 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 718 734 3.7E-9 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 749 774 3.7E-9 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 690 706 3.7E-9 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 521 535 2.3E-26 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 643 654 2.3E-26 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 741 753 2.3E-26 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 369 383 2.3E-26 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 665 675 2.3E-26 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 718 737 2.3E-26 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Pfam PF00122 E1-E2 ATPase 290 511 3.9E-64 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 523 529 - T 10-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF81665 420 515 2.48E-13 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF81665 286 323 2.48E-13 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF81665 767 786 2.48E-13 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Gene3D G3DSA:3.30.70.100 1 65 2.1E-18 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 291 795 8.1E-90 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Gene3D G3DSA:3.40.50.1000 646 786 7.8E-55 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Gene3D G3DSA:3.40.50.1000 494 534 7.8E-55 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 ProSitePatterns PS01229 Hypothetical cof family signature 2. 718 740 - T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Gene3D G3DSA:2.70.150.10 265 420 1.2E-27 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Gene3D G3DSA:3.30.70.100 101 165 4.9E-24 T 10-03-2017 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF55008 2 67 2.09E-13 T 10-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF55008 101 166 3.8E-19 T 10-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 252 827 2.3E-183 T 10-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Pfam PF00403 Heavy-metal-associated domain 105 159 3.0E-15 T 10-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 Pfam PF00403 Heavy-metal-associated domain 8 62 3.4E-11 T 10-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 RG49_RS08655 0a0881ae63fe50c130e320dcbb1582b6 834 SUPERFAMILY SSF81653 322 419 8.89E-25 T 10-03-2017 RG49_RS11635 61913914683c9ecef01d172aaaa9153e 176 Hamap MF_01414 Glutathione-regulated potassium-efflux system ancillary protein KefF [kefF]. 1 173 54.28 T 10-03-2017 IPR023948 Glutathione-regulated potassium-efflux system ancillary protein KefF GO:0006813 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 RG49_RS11635 61913914683c9ecef01d172aaaa9153e 176 SUPERFAMILY SSF52218 2 170 9.54E-47 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS11635 61913914683c9ecef01d172aaaa9153e 176 Pfam PF02525 Flavodoxin-like fold 2 167 4.3E-41 T 10-03-2017 IPR003680 Flavodoxin-like fold RG49_RS11635 61913914683c9ecef01d172aaaa9153e 176 Gene3D G3DSA:3.40.50.360 2 171 2.9E-47 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS01315 262941250e9eb4da5045bc6dd94d0b04 452 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 440 2.3E-178 T 10-03-2017 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 RG49_RS01315 262941250e9eb4da5045bc6dd94d0b04 452 PIRSF PIRSF006351 1 448 1.4E-135 T 10-03-2017 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 RG49_RS01315 262941250e9eb4da5045bc6dd94d0b04 452 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 440 2.3E-178 T 10-03-2017 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 RG49_RS01315 262941250e9eb4da5045bc6dd94d0b04 452 Pfam PF02378 Phosphotransferase system, EIIC 30 363 2.8E-47 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS11795 478475fd69d7dddfc648f53c85bf1280 283 SUPERFAMILY SSF53098 114 273 3.19E-36 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS11795 478475fd69d7dddfc648f53c85bf1280 283 Gene3D G3DSA:3.30.420.10 113 271 7.7E-29 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS11795 478475fd69d7dddfc648f53c85bf1280 283 Pfam PF00665 Integrase core domain 119 234 7.1E-30 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS11795 478475fd69d7dddfc648f53c85bf1280 283 Pfam PF13276 HTH-like domain 43 96 1.8E-15 T 10-03-2017 IPR025948 HTH-like domain RG49_RS16690 478475fd69d7dddfc648f53c85bf1280 283 SUPERFAMILY SSF53098 114 273 3.19E-36 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS16690 478475fd69d7dddfc648f53c85bf1280 283 Gene3D G3DSA:3.30.420.10 113 271 7.7E-29 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS16690 478475fd69d7dddfc648f53c85bf1280 283 Pfam PF00665 Integrase core domain 119 234 7.1E-30 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS16690 478475fd69d7dddfc648f53c85bf1280 283 Pfam PF13276 HTH-like domain 43 96 1.8E-15 T 10-03-2017 IPR025948 HTH-like domain RG49_RS08250 478475fd69d7dddfc648f53c85bf1280 283 SUPERFAMILY SSF53098 114 273 3.19E-36 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS08250 478475fd69d7dddfc648f53c85bf1280 283 Gene3D G3DSA:3.30.420.10 113 271 7.7E-29 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS08250 478475fd69d7dddfc648f53c85bf1280 283 Pfam PF00665 Integrase core domain 119 234 7.1E-30 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS08250 478475fd69d7dddfc648f53c85bf1280 283 Pfam PF13276 HTH-like domain 43 96 1.8E-15 T 10-03-2017 IPR025948 HTH-like domain RG49_RS24650 dcc64fb76fba2d1b785d27b8d5b9fec6 112 Pfam PF11776 Nickel/cobalt transporter regulator 52 101 2.8E-19 T 10-03-2017 IPR024572 Nickel/cobalt homeostasis protein RcnB RG49_RS24650 dcc64fb76fba2d1b785d27b8d5b9fec6 112 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 27 101 6.0E-40 T 10-03-2017 IPR024572 Nickel/cobalt homeostasis protein RcnB RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 Gene3D G3DSA:3.30.870.10 206 361 7.0E-33 T 10-03-2017 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 Gene3D G3DSA:3.30.870.10 4 166 9.7E-40 T 10-03-2017 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 SMART SM00155 285 312 10.0 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 SMART SM00155 108 135 1.8E-6 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 SUPERFAMILY SSF56024 4 163 1.28E-39 T 10-03-2017 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 Pfam PF13091 PLD-like domain 214 335 2.3E-25 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 Pfam PF13091 PLD-like domain 26 142 1.6E-14 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 SUPERFAMILY SSF56024 188 358 1.53E-37 T 10-03-2017 RG49_RS07085 f6a90e84d29d31a77fae7c4ce6d2fe29 413 Hamap MF_01917 Cardiolipin synthase B [clsB]. 2 383 51.999 T 10-03-2017 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 RG49_RS16200 a5f2faa458027b3a3c58e907abc60363 152 SUPERFAMILY SSF51283 1 151 7.2E-56 T 10-03-2017 IPR029054 dUTPase-like RG49_RS16200 a5f2faa458027b3a3c58e907abc60363 152 Gene3D G3DSA:2.70.40.10 6 151 4.3E-53 T 10-03-2017 IPR029054 dUTPase-like RG49_RS16200 a5f2faa458027b3a3c58e907abc60363 152 Pfam PF00692 dUTPase 17 150 6.2E-45 T 10-03-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 RG49_RS16200 a5f2faa458027b3a3c58e907abc60363 152 TIGRFAM TIGR00576 dut: dUTP diphosphatase 11 151 3.3E-50 T 10-03-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 RG49_RS16200 a5f2faa458027b3a3c58e907abc60363 152 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 7 151 34.364 T 10-03-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 RG49_RS14360 0b40b05e678b3c68befc1c668fde691b 292 Gene3D G3DSA:3.30.70.20 47 93 6.7E-4 T 10-03-2017 RG49_RS14360 0b40b05e678b3c68befc1c668fde691b 292 Pfam PF13353 4Fe-4S single cluster domain 34 144 3.4E-10 T 10-03-2017 RG49_RS14360 0b40b05e678b3c68befc1c668fde691b 292 SUPERFAMILY SSF54862 23 94 1.07E-6 T 10-03-2017 RG49_RS14360 0b40b05e678b3c68befc1c668fde691b 292 SUPERFAMILY SSF102114 74 257 1.24E-10 T 10-03-2017 RG49_RS14360 0b40b05e678b3c68befc1c668fde691b 292 ProSitePatterns PS01087 Radical activating enzymes signature. 35 56 - T 10-03-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 RG49_RS14360 0b40b05e678b3c68befc1c668fde691b 292 Pfam PF04055 Radical SAM superfamily 41 222 1.3E-21 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS14360 0b40b05e678b3c68befc1c668fde691b 292 Gene3D G3DSA:3.80.30.10 116 291 4.0E-51 T 10-03-2017 RG49_RS06190 01c2657d58570a3ef4241ab6923c6437 254 Pfam PF01435 Peptidase family M48 77 249 7.9E-27 T 10-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 RG49_RS06190 01c2657d58570a3ef4241ab6923c6437 254 Gene3D G3DSA:3.30.2010.10 70 148 1.5E-21 T 10-03-2017 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 SUPERFAMILY SSF52935 323 469 9.68E-37 T 10-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 Gene3D G3DSA:3.20.20.60 2 72 1.7E-115 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 Gene3D G3DSA:3.20.20.60 169 325 1.7E-115 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 Gene3D G3DSA:3.40.1380.20 326 469 2.7E-48 T 10-03-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 Gene3D G3DSA:2.40.33.10 73 168 8.4E-33 T 10-03-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 1.0E-29 T 10-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 10-03-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 SUPERFAMILY SSF51621 1 74 2.09E-100 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 SUPERFAMILY SSF51621 156 340 2.09E-100 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 1.7E-193 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 Pfam PF00224 Pyruvate kinase, barrel domain 1 342 3.0E-151 T 10-03-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 PRINTS PR01050 Pyruvate kinase family signature 59 75 4.3E-77 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 PRINTS PR01050 Pyruvate kinase family signature 186 200 4.3E-77 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 PRINTS PR01050 Pyruvate kinase family signature 313 329 4.3E-77 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 PRINTS PR01050 Pyruvate kinase family signature 294 312 4.3E-77 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 PRINTS PR01050 Pyruvate kinase family signature 244 268 4.3E-77 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 PRINTS PR01050 Pyruvate kinase family signature 217 243 4.3E-77 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 PRINTS PR01050 Pyruvate kinase family signature 269 293 4.3E-77 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS01655 b364e47c26991e4e943e4d21553d6140 470 SUPERFAMILY SSF50800 70 166 1.67E-29 T 10-03-2017 IPR011037 Pyruvate kinase-like, insert domain RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 10-03-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 Hamap MF_00109 Shikimate kinase [aroK]. 4 171 29.319 T 10-03-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 Pfam PF01202 Shikimate kinase 13 170 9.7E-57 T 10-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 PRINTS PR01100 Shikimate kinase family signature 59 67 3.5E-29 T 10-03-2017 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 PRINTS PR01100 Shikimate kinase family signature 98 115 3.5E-29 T 10-03-2017 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 PRINTS PR01100 Shikimate kinase family signature 7 22 3.5E-29 T 10-03-2017 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 PRINTS PR01100 Shikimate kinase family signature 31 44 3.5E-29 T 10-03-2017 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 PRINTS PR01100 Shikimate kinase family signature 77 86 3.5E-29 T 10-03-2017 RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 Gene3D G3DSA:3.40.50.300 2 172 1.4E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17635 dee49c32c984d17a3904a2dc6dbfef34 173 SUPERFAMILY SSF52540 4 170 1.07E-34 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16910 764b7af2ea04ea634318cba385bec436 691 Pfam PF05170 AsmA family 6 587 4.0E-187 T 10-03-2017 IPR007844 AsmA RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 10-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 SUPERFAMILY SSF50692 814 891 1.06E-13 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 SMART SM00926 221 275 7.0E-10 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Gene3D G3DSA:3.40.50.740 278 340 6.1E-35 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Gene3D G3DSA:3.40.50.740 504 687 6.1E-35 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Pfam PF00384 Molybdopterin oxidoreductase 562 638 8.8E-8 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Gene3D G3DSA:2.20.25.90 227 274 2.6E-14 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 78 2.4E-11 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Gene3D G3DSA:2.40.40.20 816 890 2.8E-12 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 655 3.5E-205 T 10-03-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 SUPERFAMILY SSF53706 219 688 5.54E-84 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 124 8.3E-15 T 10-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 SUPERFAMILY SSF54292 1 77 1.09E-18 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 103 115 - T 10-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 150 160 - T 10-03-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Gene3D G3DSA:3.30.70.20 198 226 1.9E-4 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Gene3D G3DSA:3.30.70.20 147 157 1.9E-4 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 221 274 9.4E-11 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Gene3D G3DSA:3.10.20.30 3 84 9.3E-8 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 SUPERFAMILY SSF54862 81 213 2.93E-34 T 10-03-2017 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 Pfam PF01568 Molydopterin dinucleotide binding domain 828 890 1.0E-6 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS23675 0a97130d8b9dad338086f6a9716d89d4 908 SMART SM00929 88 128 1.9E-19 T 10-03-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS09440 fc054851e246db76f8e9ab09f9ccbee2 219 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 39 46 - T 10-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS09440 fc054851e246db76f8e9ab09f9ccbee2 219 SUPERFAMILY SSF53056 2 202 3.14E-64 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS09440 fc054851e246db76f8e9ab09f9ccbee2 219 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 10-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS09440 fc054851e246db76f8e9ab09f9ccbee2 219 Pfam PF00484 Carbonic anhydrase 34 188 4.2E-49 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS09440 fc054851e246db76f8e9ab09f9ccbee2 219 Gene3D G3DSA:3.40.1050.10 2 202 2.1E-68 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS09440 fc054851e246db76f8e9ab09f9ccbee2 219 SMART SM00947 27 193 2.8E-66 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS05740 1fb31875f5ececcbf19d89e4988bd073 357 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 251 262 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS05740 1fb31875f5ececcbf19d89e4988bd073 357 SUPERFAMILY SSF54862 110 129 6.28E-22 T 10-03-2017 RG49_RS05740 1fb31875f5ececcbf19d89e4988bd073 357 SUPERFAMILY SSF54862 172 291 6.28E-22 T 10-03-2017 RG49_RS05740 1fb31875f5ececcbf19d89e4988bd073 357 Pfam PF12801 4Fe-4S binding domain 201 245 9.2E-8 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS05740 1fb31875f5ececcbf19d89e4988bd073 357 Pfam PF12801 4Fe-4S binding domain 97 142 1.2E-14 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS05740 1fb31875f5ececcbf19d89e4988bd073 357 Gene3D G3DSA:3.30.70.20 215 301 6.6E-15 T 10-03-2017 RG49_RS05740 1fb31875f5ececcbf19d89e4988bd073 357 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 278 289 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS14680 b6b16d9a331229bf22c983cc30566701 277 PIRSF PIRSF015626 3 277 1.4E-82 T 10-03-2017 IPR003786 Protein FdhD GO:0016783 RG49_RS14680 b6b16d9a331229bf22c983cc30566701 277 Pfam PF02634 FdhD/NarQ family 38 275 3.5E-72 T 10-03-2017 IPR003786 Protein FdhD GO:0016783 RG49_RS14680 b6b16d9a331229bf22c983cc30566701 277 Gene3D G3DSA:3.10.20.10 40 125 5.0E-32 T 10-03-2017 RG49_RS14680 b6b16d9a331229bf22c983cc30566701 277 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 13 276 33.739 T 10-03-2017 IPR003786 Protein FdhD GO:0016783 RG49_RS14680 b6b16d9a331229bf22c983cc30566701 277 Gene3D G3DSA:3.40.140.10 139 275 7.5E-50 T 10-03-2017 RG49_RS14680 b6b16d9a331229bf22c983cc30566701 277 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 34 277 1.8E-102 T 10-03-2017 IPR003786 Protein FdhD GO:0016783 RG49_RS14680 b6b16d9a331229bf22c983cc30566701 277 SUPERFAMILY SSF53927 22 275 9.63E-82 T 10-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 RG49_RS06750 b4db6b67d2460411c20a627d8a9edb88 169 Pfam PF06892 Phage regulatory protein CII (CP76) 4 160 1.1E-67 T 10-03-2017 IPR009679 Bacteriophage 186, CII RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 Pfam PF01165 Ribosomal protein S21 4 56 5.1E-22 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.283 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 56 1.0E-15 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 10-03-2017 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 2.8E-17 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 2.8E-17 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 2.8E-17 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 2.8E-17 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS19405 e0f63aa874b218a4c9d359851efe3e90 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 4.1E-24 T 10-03-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Pfam PF00989 PAS fold 156 266 1.1E-17 T 10-03-2017 IPR013767 PAS fold GO:0006355 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 276 1.5E-13 T 10-03-2017 IPR000014 PAS domain RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SUPERFAMILY SSF55874 336 503 3.41E-43 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Gene3D G3DSA:3.30.450.20 141 267 3.7E-20 T 10-03-2017 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SMART SM00387 394 507 2.0E-36 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 PIRSF PIRSF003182 1 778 0.0 T 10-03-2017 IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB GO:0000155|GO:0000160|GO:0004673|GO:0016021 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 504 4.2E-30 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Gene3D G3DSA:1.10.287.970 1 89 3.3E-41 T 10-03-2017 IPR027460 Aerobic respiration control sensor protein ArcB, transmembrane domain RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SMART SM00073 675 772 3.9E-23 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SUPERFAMILY SSF47384 269 347 3.92E-17 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Pfam PF01627 Hpt domain 686 760 1.5E-10 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SUPERFAMILY SSF55785 140 267 3.49E-20 T 10-03-2017 IPR000014 PAS domain RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 445 2.0E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 459 2.0E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 485 2.0E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 2.0E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 346 2.4E-15 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Gene3D G3DSA:3.40.50.2300 524 648 6.3E-32 T 10-03-2017 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SMART SM00388 282 347 5.6E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Pfam PF00072 Response regulator receiver domain 528 639 5.8E-22 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SMART SM00448 526 639 7.9E-26 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Gene3D G3DSA:3.30.565.10 348 506 9.4E-46 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Gene3D G3DSA:1.20.120.160 676 776 6.4E-35 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SUPERFAMILY SSF52172 526 647 1.99E-27 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 Gene3D G3DSA:1.10.287.130 274 343 1.2E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SUPERFAMILY SSF47226 661 773 1.7E-27 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS18590 194ab80cc2a4c255030c3792403ba6b2 778 SMART SM00091 155 221 4.3E-7 T 10-03-2017 IPR000014 PAS domain RG49_RS05080 81001b797bbba7ea9a7f1a2a88c3f213 210 SUPERFAMILY SSF48498 92 206 5.34E-27 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS05080 81001b797bbba7ea9a7f1a2a88c3f213 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 1.9E-15 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS05080 81001b797bbba7ea9a7f1a2a88c3f213 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 3.9E-5 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS05080 81001b797bbba7ea9a7f1a2a88c3f213 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 3.9E-5 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS05080 81001b797bbba7ea9a7f1a2a88c3f213 210 Gene3D G3DSA:1.10.357.10 84 209 1.1E-42 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS05080 81001b797bbba7ea9a7f1a2a88c3f213 210 SUPERFAMILY SSF46689 11 83 9.75E-18 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS05080 81001b797bbba7ea9a7f1a2a88c3f213 210 Gene3D G3DSA:1.10.10.60 12 78 3.9E-25 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS23420 173e7a05f33e34e22f1201d66fde48fd 183 Pfam PF01713 Smr domain 98 172 1.0E-17 T 10-03-2017 IPR002625 Smr domain RG49_RS23420 173e7a05f33e34e22f1201d66fde48fd 183 SUPERFAMILY SSF160443 96 170 2.22E-9 T 10-03-2017 IPR002625 Smr domain RG49_RS23420 173e7a05f33e34e22f1201d66fde48fd 183 Hamap MF_01042 UPF0115 protein YfcN [yfcN]. 1 174 42.647 T 10-03-2017 IPR022990 Uncharacterised protein family UPF0115 RG49_RS23420 173e7a05f33e34e22f1201d66fde48fd 183 SMART SM00463 95 173 7.9E-23 T 10-03-2017 IPR002625 Smr domain RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 7.1E-18 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 Pfam PF03466 LysR substrate binding domain 97 281 3.4E-27 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 Gene3D G3DSA:3.40.190.10 96 190 2.2E-15 T 10-03-2017 RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 Gene3D G3DSA:1.10.10.10 10 91 6.4E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 SUPERFAMILY SSF46785 11 119 2.12E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 Gene3D G3DSA:3.40.190.10 191 246 2.3E-9 T 10-03-2017 RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 SUPERFAMILY SSF53850 96 292 6.15E-29 T 10-03-2017 RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 2.4E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 2.4E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23645 e270736cd58547ea99ec4b6d84f2ddbb 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 2.4E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS22230 5d741571fc120864525d08b94a73b46b 126 SUPERFAMILY SSF56214 3 125 9.55E-30 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS22230 5d741571fc120864525d08b94a73b46b 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 126 3.7E-62 T 10-03-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 RG49_RS22230 5d741571fc120864525d08b94a73b46b 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 121 5.8E-24 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS22230 5d741571fc120864525d08b94a73b46b 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 23 87 8.0E-33 T 10-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 RG49_RS22230 5d741571fc120864525d08b94a73b46b 126 Gene3D G3DSA:3.90.470.20 1 125 1.1E-41 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS22230 5d741571fc120864525d08b94a73b46b 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 26.733 T 10-03-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 RG49_RS22230 5d741571fc120864525d08b94a73b46b 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 126 1.6E-40 T 10-03-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 SMART SM00956 413 516 4.9E-48 T 10-03-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 SUPERFAMILY SSF52540 210 458 1.89E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 SMART SM00487 24 218 2.2E-30 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Gene3D G3DSA:1.10.150.80 532 603 5.4E-24 T 10-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 SMART SM00490 252 333 8.1E-29 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Gene3D G3DSA:1.10.10.10 347 517 6.2E-61 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 SUPERFAMILY SSF47819 532 607 3.27E-26 T 10-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Gene3D G3DSA:3.40.50.300 8 204 2.7E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 17 466 3.6E-210 T 10-03-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Gene3D G3DSA:3.40.50.300 208 346 4.0E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 SMART SM00341 531 611 1.9E-31 T 10-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Pfam PF00270 DEAD/DEAH box helicase 30 189 1.9E-19 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Pfam PF00271 Helicase conserved C-terminal domain 226 333 1.2E-20 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Pfam PF16124 RecQ zinc-binding 345 406 9.7E-16 T 10-03-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Pfam PF00570 HRDC domain 535 601 3.4E-23 T 10-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 Pfam PF09382 RQC domain 408 516 5.1E-35 T 10-03-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 SUPERFAMILY SSF52540 9 203 2.03E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15080 9ef0bf2f8e62a0909191c31ace61f6f9 611 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 15 603 4.9E-281 T 10-03-2017 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 512 2.6E-262 T 10-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 SUPERFAMILY SSF47917 383 511 4.19E-46 T 10-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 SUPERFAMILY SSF50615 10 94 2.55E-25 T 10-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 Gene3D G3DSA:3.40.50.300 94 382 1.4E-113 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 4.4E-74 T 10-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.1E-45 T 10-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 Gene3D G3DSA:1.20.150.20 383 510 3.6E-49 T 10-03-2017 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 Gene3D G3DSA:2.40.30.20 1 93 3.5E-29 T 10-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 SUPERFAMILY SSF52540 96 381 9.43E-95 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 49.882 T 10-03-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 92 1.6E-12 T 10-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15540 5eedc69dcc8a494aac3431061697c90c 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 10-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS16350 f93f64fdf3f900b3f6a70f31ea436868 143 Gene3D G3DSA:3.40.250.10 22 142 2.8E-27 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS16350 f93f64fdf3f900b3f6a70f31ea436868 143 SUPERFAMILY SSF52821 15 142 2.62E-30 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS16350 f93f64fdf3f900b3f6a70f31ea436868 143 Pfam PF00581 Rhodanese-like domain 43 133 9.1E-17 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS16350 f93f64fdf3f900b3f6a70f31ea436868 143 SMART SM00450 40 138 9.5E-22 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS11560 efea8bfe9c9f11541cd17a3ebcc418d0 500 PIRSF PIRSF001478 1 500 1.0E-259 T 10-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 RG49_RS11560 efea8bfe9c9f11541cd17a3ebcc418d0 500 SUPERFAMILY SSF50443 329 497 4.45E-71 T 10-03-2017 IPR004216 L-fucose/L-arabinose isomerase, C-terminal RG49_RS11560 efea8bfe9c9f11541cd17a3ebcc418d0 500 Pfam PF02610 L-arabinose isomerase 5 359 1.6E-179 T 10-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 RG49_RS11560 efea8bfe9c9f11541cd17a3ebcc418d0 500 Hamap MF_00519 L-arabinose isomerase [araA]. 1 477 64.854 T 10-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 RG49_RS11560 efea8bfe9c9f11541cd17a3ebcc418d0 500 Pfam PF11762 L-arabinose isomerase C-terminal domain 363 476 8.4E-46 T 10-03-2017 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 RG49_RS11560 efea8bfe9c9f11541cd17a3ebcc418d0 500 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 1 303 0.0 T 10-03-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 RG49_RS11560 efea8bfe9c9f11541cd17a3ebcc418d0 500 SUPERFAMILY SSF53743 1 326 8.89E-126 T 10-03-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 Gene3D G3DSA:3.40.250.10 140 278 1.4E-35 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 Gene3D G3DSA:3.40.250.10 10 127 1.2E-10 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 ProSitePatterns PS00380 Rhodanese signature 1. 181 192 - T 10-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 ProSitePatterns PS00683 Rhodanese C-terminal signature. 406 416 - T 10-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 SMART SM00450 26 139 3.8E-4 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 SMART SM00450 294 422 2.1E-15 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 SMART SM00450 146 267 2.8E-19 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 SUPERFAMILY SSF52821 288 428 3.8E-31 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 Pfam PF00581 Rhodanese-like domain 179 263 1.1E-11 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 Pfam PF00581 Rhodanese-like domain 297 418 2.2E-11 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 Gene3D G3DSA:3.40.250.10 289 428 1.1E-31 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 SUPERFAMILY SSF52821 33 128 4.19E-8 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS01205 5ab56785f11dc856ccf904d749605fdc 435 SUPERFAMILY SSF52821 141 275 2.88E-27 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS21895 5ac308bd10e4fee59515796b3f6ae3be 72 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 9 59 5.7E-23 T 10-03-2017 IPR010260 Prophage CP4-57 regulatory protein (AlpA) RG49_RS21895 5ac308bd10e4fee59515796b3f6ae3be 72 Gene3D G3DSA:1.10.10.10 14 64 1.1E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21895 5ac308bd10e4fee59515796b3f6ae3be 72 SUPERFAMILY SSF46955 10 62 6.77E-6 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 3 153 1.3E-55 T 10-03-2017 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 PRINTS PR00446 Hydrogen uptake protein signature 56 66 8.7E-24 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 PRINTS PR00446 Hydrogen uptake protein signature 35 52 8.7E-24 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 PRINTS PR00446 Hydrogen uptake protein signature 3 15 8.7E-24 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 PRINTS PR00446 Hydrogen uptake protein signature 15 26 8.7E-24 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 PRINTS PR00446 Hydrogen uptake protein signature 68 84 8.7E-24 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 Gene3D G3DSA:3.40.50.1450 1 158 1.4E-52 T 10-03-2017 IPR023430 Peptidase HybD-like domain RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 Pfam PF01750 Hydrogenase maturation protease 20 147 1.3E-37 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 SUPERFAMILY SSF53163 1 159 3.53E-46 T 10-03-2017 IPR023430 Peptidase HybD-like domain RG49_RS19795 6b8d2f28091535c5185ecdc941bd4798 164 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 148 4.4E-46 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 Gene3D G3DSA:3.40.47.10 221 299 2.4E-50 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 Gene3D G3DSA:3.40.47.10 15 134 2.4E-50 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 ProSitePatterns PS00737 Thiolases signature 2. 382 398 - T 10-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 Hamap MF_01618 3-ketoacyl-CoA thiolase [fadI]. 2 436 75.765 T 10-03-2017 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0005737|GO:0006631|GO:0016042|GO:0016740|GO:0016746 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 Gene3D G3DSA:3.40.47.10 175 220 5.9E-49 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 Gene3D G3DSA:3.40.47.10 302 435 5.9E-49 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 ProSitePatterns PS00099 Thiolases active site. 417 430 - T 10-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 TIGRFAM TIGR02446 FadI: acetyl-CoA C-acyltransferase FadI 7 436 2.6E-274 T 10-03-2017 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0005737|GO:0006631|GO:0016042|GO:0016740|GO:0016746 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 17 434 1.0E-135 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 SUPERFAMILY SSF53901 297 434 5.77E-33 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 Pfam PF02803 Thiolase, C-terminal domain 297 434 2.8E-36 T 10-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 95 113 - T 10-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 PIRSF PIRSF000429 9 436 6.4E-127 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 SUPERFAMILY SSF53901 15 295 1.15E-62 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23370 4c91de5c91649883675fd57c3e8177f0 436 Pfam PF00108 Thiolase, N-terminal domain 15 288 6.1E-60 T 10-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 RG49_RS03880 d4a403dcc47818d890ad52fb39fd443f 343 SUPERFAMILY SSF82861 79 160 1.96E-10 T 10-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 RG49_RS03880 d4a403dcc47818d890ad52fb39fd443f 343 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 194 228 - T 10-03-2017 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 RG49_RS03880 d4a403dcc47818d890ad52fb39fd443f 343 SUPERFAMILY SSF50182 162 228 1.37E-17 T 10-03-2017 IPR010920 LSM domain RG49_RS03880 d4a403dcc47818d890ad52fb39fd443f 343 Gene3D G3DSA:2.30.30.60 178 228 4.5E-15 T 10-03-2017 RG49_RS03880 d4a403dcc47818d890ad52fb39fd443f 343 Gene3D G3DSA:3.30.70.100 233 321 2.7E-16 T 10-03-2017 RG49_RS03880 d4a403dcc47818d890ad52fb39fd443f 343 SUPERFAMILY SSF82689 231 335 8.37E-22 T 10-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 RG49_RS03880 d4a403dcc47818d890ad52fb39fd443f 343 Pfam PF00924 Mechanosensitive ion channel 120 323 1.2E-63 T 10-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 RG49_RS12130 fcc61c0ea47cfb1f334791ad9d324d25 179 Hamap MF_01061 Primosomal protein 1 [dnaT]. 3 179 44.343 T 10-03-2017 IPR020917 Primosomal protein 1 GO:0006260 RG49_RS04520 6a49765cd74e90978903b492853465f7 464 Pfam PF11924 Invasin beta-domain of outer membrane 64 341 1.8E-100 T 10-03-2017 IPR024519 Invasin beta-domain of outer membrane RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 Gene3D G3DSA:3.30.1330.10 29 162 4.1E-32 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 Gene3D G3DSA:3.90.650.10 176 344 4.6E-20 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 Hamap MF_00625 Selenide, water dikinase [selD]. 5 347 45.347 T 10-03-2017 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 TIGRFAM TIGR00476 selD: selenide, water dikinase 7 313 2.4E-134 T 10-03-2017 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 SUPERFAMILY SSF55326 7 161 5.38E-41 T 10-03-2017 RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 SUPERFAMILY SSF56042 164 340 1.94E-50 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 PIRSF PIRSF036407 1 346 5.0E-117 T 10-03-2017 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 344 3.5E-32 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS01170 cafca265a3bf7afba1ec32aea9845b77 347 Pfam PF00586 AIR synthase related protein, N-terminal domain 50 157 5.7E-19 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 115 134 5.7E-6 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 55 69 5.7E-6 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 197 205 5.7E-6 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 SUPERFAMILY SSF54292 221 321 1.7E-25 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 Gene3D G3DSA:3.40.50.80 106 225 5.9E-23 T 10-03-2017 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 Gene3D G3DSA:3.10.20.30 226 321 3.5E-26 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 Pfam PF00970 Oxidoreductase FAD-binding domain 17 104 1.1E-7 T 10-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 SUPERFAMILY SSF52343 95 220 4.85E-25 T 10-03-2017 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 248 315 3.0E-14 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 SUPERFAMILY SSF63380 9 105 4.15E-21 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 Pfam PF00175 Oxidoreductase NAD-binding domain 116 210 4.5E-7 T 10-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 RG49_RS06400 37c1b625531bd8753073f23acdb6b836 322 Gene3D G3DSA:2.40.30.10 10 105 2.6E-18 T 10-03-2017 RG49_RS10640 c518a0ceadc34e89307770e377f68e41 137 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 10 136 6.4E-35 T 10-03-2017 IPR017737 Type VI secretion system, lysozyme-related protein RG49_RS10640 c518a0ceadc34e89307770e377f68e41 137 Pfam PF04965 Gene 25-like lysozyme 31 114 3.0E-15 T 10-03-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD RG49_RS10640 c518a0ceadc34e89307770e377f68e41 137 Gene3D G3DSA:3.10.450.40 23 125 1.4E-15 T 10-03-2017 RG49_RS10640 c518a0ceadc34e89307770e377f68e41 137 SUPERFAMILY SSF160719 27 126 7.45E-18 T 10-03-2017 RG49_RS08715 19816cf0ce1cd4f4f9a55d83b338530c 319 Gene3D G3DSA:3.40.50.1820 13 316 9.4E-70 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS08715 19816cf0ce1cd4f4f9a55d83b338530c 319 Pfam PF07859 alpha/beta hydrolase fold 87 295 7.9E-53 T 10-03-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 RG49_RS08715 19816cf0ce1cd4f4f9a55d83b338530c 319 Hamap MF_01958 Acetyl esterase [aes]. 1 319 73.361 T 10-03-2017 IPR023508 Acetyl esterase GO:0005737|GO:0052689 RG49_RS08715 19816cf0ce1cd4f4f9a55d83b338530c 319 SUPERFAMILY SSF53474 29 316 1.12E-57 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS08715 19816cf0ce1cd4f4f9a55d83b338530c 319 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 87 103 - T 10-03-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 RG49_RS08715 19816cf0ce1cd4f4f9a55d83b338530c 319 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 159 171 - T 10-03-2017 IPR033140 Lipase, GDXG, putative serine active site RG49_RS22050 a68deb744c5ccb18558880eee58b12bf 245 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 4 242 39.289 T 10-03-2017 IPR017689 Outer membrane protein assembly factor BamD RG49_RS22050 a68deb744c5ccb18558880eee58b12bf 245 Gene3D G3DSA:1.25.40.10 29 234 3.0E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22050 a68deb744c5ccb18558880eee58b12bf 245 Pfam PF13525 Outer membrane lipoprotein 28 236 1.4E-83 T 10-03-2017 RG49_RS22050 a68deb744c5ccb18558880eee58b12bf 245 SUPERFAMILY SSF48452 27 121 4.96E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22050 a68deb744c5ccb18558880eee58b12bf 245 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 5 243 3.6E-88 T 10-03-2017 IPR017689 Outer membrane protein assembly factor BamD RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 PIRSF PIRSF006205 1 398 4.7E-161 T 10-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 Gene3D G3DSA:1.10.1740.10 313 395 9.0E-31 T 10-03-2017 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 SUPERFAMILY SSF69055 301 393 1.7E-30 T 10-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 392 47.544 T 10-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 Gene3D G3DSA:3.40.50.720 1 150 2.6E-60 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 239 5.8E-36 T 10-03-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 397 1.5E-199 T 10-03-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 SUPERFAMILY SSF55347 126 274 1.11E-62 T 10-03-2017 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 7.4E-50 T 10-03-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 SUPERFAMILY SSF51735 2 150 1.27E-48 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS10950 e8cd2b09ad65623d0bbb2d02485e3fcb 398 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 387 1.7E-41 T 10-03-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 RG49_RS13325 62bbf7dad703c9502be42d1679853d2e 239 Gene3D G3DSA:1.10.10.60 160 192 4.1E-4 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13325 62bbf7dad703c9502be42d1679853d2e 239 SUPERFAMILY SSF52172 1 136 1.34E-28 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS13325 62bbf7dad703c9502be42d1679853d2e 239 SMART SM00448 2 117 5.5E-22 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS13325 62bbf7dad703c9502be42d1679853d2e 239 Gene3D G3DSA:3.40.50.2300 1 129 4.0E-24 T 10-03-2017 RG49_RS13325 62bbf7dad703c9502be42d1679853d2e 239 PIRSF PIRSF006171 1 230 1.9E-83 T 10-03-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 RG49_RS13325 62bbf7dad703c9502be42d1679853d2e 239 Pfam PF00072 Response regulator receiver domain 4 117 4.5E-19 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 Gene3D G3DSA:1.10.10.10 132 235 1.3E-32 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 1.7E-22 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 Pfam PF00072 Response regulator receiver domain 7 117 1.3E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 SMART SM00862 156 232 1.7E-23 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 SUPERFAMILY SSF46894 132 234 2.07E-26 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 SMART SM00448 5 116 8.6E-45 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 SUPERFAMILY SSF52172 3 126 8.4E-42 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS17555 d8521a76d5088ea0467c0daab9e28465 239 Gene3D G3DSA:3.40.50.2300 4 127 1.4E-42 T 10-03-2017 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 6 407 35.87 T 10-03-2017 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 Gene3D G3DSA:1.10.3860.10 12 404 6.9E-85 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 18 38 1.5E-10 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 1.5E-10 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 1.5E-10 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 1.5E-10 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 SUPERFAMILY SSF118215 18 400 4.71E-95 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS19260 efe214b8057415f7acec0db41016c74e 414 Pfam PF00375 Sodium:dicarboxylate symporter family 18 397 4.6E-63 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 TIGRFAM TIGR01276 thiB: thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein 6 327 1.1E-194 T 10-03-2017 IPR005967 Proteobacterial thiamine ABC transporter, periplasmic binding protein GO:0005524|GO:0015888|GO:0030288|GO:0048502 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 119 136 - T 10-03-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 18 321 8.5E-157 T 10-03-2017 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 SUPERFAMILY SSF53850 22 323 7.25E-64 T 10-03-2017 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 Gene3D G3DSA:3.40.190.10 122 258 2.5E-25 T 10-03-2017 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 Pfam PF13343 Bacterial extracellular solute-binding protein 73 289 7.2E-17 T 10-03-2017 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 Gene3D G3DSA:3.40.190.10 15 120 1.5E-15 T 10-03-2017 RG49_RS11525 fd40beded8d9804486fa4af8597ddaa3 327 Gene3D G3DSA:3.40.190.10 259 316 1.5E-15 T 10-03-2017 RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 Pfam PF00753 Metallo-beta-lactamase superfamily 12 165 1.7E-22 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 251 45.5 T 10-03-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 Gene3D G3DSA:3.60.15.10 5 251 6.0E-86 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 SMART SM00849 11 165 1.2E-38 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 PIRSF PIRSF005457 1 251 6.0E-90 T 10-03-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 SUPERFAMILY SSF56281 1 251 1.44E-68 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 166 251 3.3E-22 T 10-03-2017 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 RG49_RS10745 c55ad0d1668b478525d2b681a1266f70 251 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 251 5.8E-104 T 10-03-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 RG49_RS11695 7eb6bd2c94761433421924b3c383004f 131 ProDom PD081346 TRANSCRIPTIONAL CAIF OPERON REGULATOR CAI ACTIVATOR TRANSCRIPTION ACTIVATORY FIX REGULATION 1 131 5.0E-72 T 10-03-2017 IPR020357 Transcription regulator CaiF/GrlA GO:0006351 RG49_RS11695 7eb6bd2c94761433421924b3c383004f 131 Pfam PF07180 Protein of unknown function (DUF1401) 5 61 5.1E-6 T 10-03-2017 IPR020357 Transcription regulator CaiF/GrlA GO:0006351 RG49_RS00850 ef043d767ee531f86c186a863bf7fcef 269 SUPERFAMILY SSF53335 4 250 3.32E-56 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00850 ef043d767ee531f86c186a863bf7fcef 269 Gene3D G3DSA:3.40.50.150 70 213 3.3E-26 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00850 ef043d767ee531f86c186a863bf7fcef 269 Pfam PF13847 Methyltransferase domain 84 196 1.3E-15 T 10-03-2017 IPR025714 Methyltransferase domain RG49_RS00850 ef043d767ee531f86c186a863bf7fcef 269 PIRSF PIRSF018249 1 268 2.9E-94 T 10-03-2017 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 SUPERFAMILY SSF55874 517 677 6.3E-14 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 Pfam PF01627 Hpt domain 811 868 3.2E-10 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 Pfam PF16359 RcsD-ABL domain 688 789 2.3E-39 T 10-03-2017 IPR032306 Phosphotransferase RcsD, RcsD-ABL domain RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 SMART SM00387 565 678 6.6E-7 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 565 675 6.8E-10 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 SUPERFAMILY SSF47226 803 889 1.7E-21 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 Gene3D G3DSA:1.20.120.160 776 889 6.3E-36 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 Gene3D G3DSA:3.30.565.10 523 677 2.1E-16 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24035 7d54a80c4bb771f434751937e4c0707e 890 Hamap MF_00980 Phosphotransferase RcsD [rcsD]. 15 890 24.811 T 10-03-2017 IPR030861 Phosphotransferase RcsD GO:0000160|GO:0005887|GO:0009927 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Pfam PF00122 E1-E2 ATPase 123 362 1.3E-59 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Gene3D G3DSA:2.70.150.10 60 97 1.3E-43 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Gene3D G3DSA:2.70.150.10 150 271 1.3E-43 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 SMART SM00831 44 117 1.4E-7 T 10-03-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 SUPERFAMILY SSF81653 168 270 2.88E-29 T 10-03-2017 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 SUPERFAMILY SSF56784 532 683 5.76E-38 T 10-03-2017 IPR023214 HAD-like domain RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Pfam PF00690 Cation transporter/ATPase, N-terminus 48 112 3.0E-15 T 10-03-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 SUPERFAMILY SSF81665 272 365 3.66E-105 T 10-03-2017 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 SUPERFAMILY SSF81665 46 155 3.66E-105 T 10-03-2017 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 SUPERFAMILY SSF81665 688 896 3.66E-105 T 10-03-2017 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 301 320 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 852 873 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 284 300 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 697 712 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 405 418 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 715 726 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 802 823 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 747 760 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 PRINTS PR01836 Magnesium-transporting ATPase signature 767 783 2.4E-85 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Pfam PF00689 Cation transporting ATPase, C-terminus 722 888 3.6E-14 T 10-03-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 34 898 0.0 T 10-03-2017 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Gene3D G3DSA:3.40.1110.10 363 546 1.1E-37 T 10-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 373 379 - T 10-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Pfam PF00702 haloacid dehalogenase-like hydrolase 367 653 1.5E-19 T 10-03-2017 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 123 407 1.9E-38 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 606 728 5.1E-31 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 SUPERFAMILY SSF81660 340 543 2.07E-41 T 10-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Gene3D G3DSA:1.20.1110.10 608 890 2.4E-69 T 10-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 RG49_RS12680 059a5302ebabe7d37217b94b53229d6e 898 Gene3D G3DSA:1.20.1110.10 98 149 2.4E-69 T 10-03-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 SUPERFAMILY SSF51735 240 271 3.38E-52 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 SUPERFAMILY SSF51735 4 130 3.38E-52 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 Gene3D G3DSA:3.40.50.720 5 167 1.0E-61 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 SUPERFAMILY SSF55347 131 240 1.44E-37 T 10-03-2017 RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 129 4.3E-41 T 10-03-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 6 269 35.14 T 10-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 6 269 1.1E-112 T 10-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 154 171 - T 10-03-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 268 6.8E-43 T 10-03-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS11715 143036f316b04f661ef1cc0850d96702 273 PIRSF PIRSF000161 4 272 4.4E-92 T 10-03-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS07615 26bd14f81ed42af3a88687312905013b 190 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 3 188 7.8E-101 T 10-03-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 RG49_RS07615 26bd14f81ed42af3a88687312905013b 190 Pfam PF02669 K+-transporting ATPase, c chain 5 187 1.7E-67 T 10-03-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 RG49_RS07615 26bd14f81ed42af3a88687312905013b 190 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 188 32.737 T 10-03-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 RG49_RS07615 26bd14f81ed42af3a88687312905013b 190 PIRSF PIRSF001296 1 190 1.5E-72 T 10-03-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 Gene3D G3DSA:3.90.1150.10 426 586 5.2E-66 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 Gene3D G3DSA:3.40.640.10 130 423 5.3E-100 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 14 124 5.7E-27 T 10-03-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 570 700 2.4E-46 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 SUPERFAMILY SSF53383 130 562 1.08E-102 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 130 545 1.2E-195 T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 SUPERFAMILY SSF55904 566 708 3.27E-43 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 362 376 - T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 Gene3D G3DSA:3.90.100.10 587 709 9.0E-38 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS10885 38161fdde05e685426cddf9bec774f52 713 PIRSF PIRSF009393 1 712 3.8E-281 T 10-03-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 RG49_RS04965 0a0d0a63de134b3aebe1bc2f9c027855 373 Pfam PF08007 Cupin superfamily protein 10 310 1.2E-104 T 10-03-2017 IPR003347 JmjC domain RG49_RS04965 0a0d0a63de134b3aebe1bc2f9c027855 373 SMART SM00558 92 215 2.1E-11 T 10-03-2017 IPR003347 JmjC domain RG49_RS04965 0a0d0a63de134b3aebe1bc2f9c027855 373 Gene3D G3DSA:2.60.120.650 7 206 7.0E-45 T 10-03-2017 RG49_RS04965 0a0d0a63de134b3aebe1bc2f9c027855 373 SUPERFAMILY SSF51197 7 292 2.47E-75 T 10-03-2017 RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 SMART SM00895 159 287 7.6E-11 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 SUPERFAMILY SSF46785 3 70 1.04E-8 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 61 5.6E-6 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 2.1E-6 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 2.1E-6 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 SUPERFAMILY SSF48008 157 294 2.2E-13 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 Gene3D G3DSA:1.20.120.530 154 299 1.7E-14 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 Gene3D G3DSA:1.10.10.10 3 72 9.9E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 Pfam PF07729 FCD domain 159 286 2.6E-9 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS12155 281de47c1a4c91ebd5601642456c759b 301 Gene3D G3DSA:1.10.10.10 95 146 2.1E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 SUPERFAMILY SSF48452 42 134 4.84E-8 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 4 387 37.088 T 10-03-2017 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 SUPERFAMILY SSF48452 105 280 6.83E-17 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 Gene3D G3DSA:1.25.40.10 237 331 5.0E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 Gene3D G3DSA:1.25.40.10 112 236 1.2E-18 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 Gene3D G3DSA:1.25.40.10 47 95 1.3E-4 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 Pfam PF14559 Tetratricopeptide repeat 191 246 1.3E-6 T 10-03-2017 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 SMART SM00028 141 174 470.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 SMART SM00028 180 213 32.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 SMART SM00028 107 140 390.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 SMART SM00028 214 247 0.034 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS04160 17f7620be9160a140f27aa0b26f6c652 389 SMART SM00028 69 102 59.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS00325 33fb3d053aad10fe4b94b1aac17a4bd1 74 Pfam PF10769 Protein of unknown function (DUF2594) 1 74 2.1E-36 T 10-03-2017 IPR019705 Protein of unknown function DUF2594 RG49_RS23920 b5ec566bfbe36672b78744d86c0b9e27 216 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 11 213 1.8E-72 T 10-03-2017 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 RG49_RS23920 b5ec566bfbe36672b78744d86c0b9e27 216 SUPERFAMILY SSF56112 8 216 1.47E-14 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS23920 b5ec566bfbe36672b78744d86c0b9e27 216 PIRSF PIRSF026326 1 216 3.4E-62 T 10-03-2017 IPR027023 Putative lipopolysaccharide kinase InaA RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Gene3D G3DSA:1.10.1040.10 494 586 3.9E-29 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 SUPERFAMILY SSF52096 6 299 6.22E-70 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Gene3D G3DSA:3.40.50.720 305 493 6.6E-56 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 311 489 4.8E-60 T 10-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 204 1.5E-43 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 618 703 5.1E-5 T 10-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 492 586 2.0E-28 T 10-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 SUPERFAMILY SSF48179 492 595 5.36E-28 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 SUPERFAMILY SSF51735 308 489 5.7E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Gene3D G3DSA:1.10.1040.10 624 709 1.5E-22 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 SUPERFAMILY SSF48179 614 706 1.36E-24 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 489 513 - T 10-03-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 TIGRFAM TIGR02440 FadJ: fatty oxidation complex, alpha subunit FadJ 6 706 0.0 T 10-03-2017 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Hamap MF_01617 Fatty acid oxidation complex subunit alpha [fadJ]. 1 706 54.309 T 10-03-2017 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS23375 a8e94f72da7fdfee1e06807df0f9b845 714 Gene3D G3DSA:3.90.226.10 2 204 1.5E-68 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 SUPERFAMILY SSF63411 4 162 3.2E-67 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 159 36.375 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 PIRSF PIRSF006160 1 162 3.4E-66 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 155 4.0E-85 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 121 140 1.6E-50 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 1.6E-50 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 1.6E-50 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 1.6E-50 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 77 95 1.6E-50 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 Gene3D G3DSA:3.30.1360.80 1 170 2.9E-76 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS21655 9e01ce4838b08bee8178f00a8b68ada0 171 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 152 1.5E-62 T 10-03-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 Gene3D G3DSA:3.40.1060.10 520 682 8.1E-89 T 10-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 Pfam PF00330 Aconitase family (aconitate hydratase) 472 818 7.3E-40 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 Gene3D G3DSA:3.20.19.10 162 361 1.8E-95 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 Gene3D G3DSA:3.30.499.10 403 519 3.6E-64 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 SUPERFAMILY SSF52016 163 371 9.16E-73 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 PIRSF PIRSF036687 1 859 0.0 T 10-03-2017 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 ProSitePatterns PS00450 Aconitase family signature 1. 702 719 - T 10-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 Gene3D G3DSA:3.30.499.10 684 859 6.8E-56 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 SUPERFAMILY SSF74778 2 160 6.02E-70 T 10-03-2017 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 SUPERFAMILY SSF53732 380 859 2.22E-150 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 854 0.0 T 10-03-2017 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 10-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 Pfam PF11791 Aconitate B N-terminal domain 4 156 9.8E-69 T 10-03-2017 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 RG49_RS11260 7d336b5df5ac770aa74177e115067efa 865 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 4.2E-98 T 10-03-2017 IPR015929 Aconitase B, N-terminal GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 SUPERFAMILY SSF47203 272 494 1.19E-44 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 Gene3D G3DSA:2.40.110.10 152 273 1.5E-46 T 10-03-2017 RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 Gene3D G3DSA:1.10.3140.10 12 150 6.2E-58 T 10-03-2017 RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 Gene3D G3DSA:1.20.140.10 274 490 2.1E-35 T 10-03-2017 RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 15 281 6.7E-93 T 10-03-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 PIRSF PIRSF000331 11 501 7.4E-205 T 10-03-2017 IPR004925 HpaB/PvcC/4-BUDH RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 PIRSF PIRSF500125 1 518 3.5E-290 T 10-03-2017 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 TIGRFAM TIGR02310 HpaB-2: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 2 520 0.0 T 10-03-2017 IPR012688 4-HPA 3-monooxygenase large component, gammaproteobacteria GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 288 489 3.0E-64 T 10-03-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal RG49_RS12230 e8954cb3123e879ba86c5f1ce29a02c5 520 SUPERFAMILY SSF56645 13 282 8.35E-83 T 10-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 Gene3D G3DSA:3.60.120.10 4 516 2.5E-161 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 PRINTS PR00095 Anthranilate synthase component I signature 350 363 6.9E-24 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 PRINTS PR00095 Anthranilate synthase component I signature 444 458 6.9E-24 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 PRINTS PR00095 Anthranilate synthase component I signature 364 377 6.9E-24 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 PRINTS PR00095 Anthranilate synthase component I signature 459 473 6.9E-24 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 Pfam PF00425 chorismate binding enzyme 242 502 5.1E-82 T 10-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 TIGRFAM TIGR00565 trpE_proteo: anthranilate synthase component I 17 515 1.2E-281 T 10-03-2017 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 SUPERFAMILY SSF56322 7 516 2.35E-164 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 PIRSF PIRSF001373 1 520 3.6E-251 T 10-03-2017 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS04265 1257fab5b110f1dc5c33be728facf3db 520 Pfam PF04715 Anthranilate synthase component I, N terminal region 19 191 5.4E-13 T 10-03-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS19730 01253ca20e74209bc3ba1c7febf7acff 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 134 8.7E-31 T 10-03-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 RG49_RS19730 01253ca20e74209bc3ba1c7febf7acff 141 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 15 136 1.7E-70 T 10-03-2017 IPR014170 TonB system transport protein ExbD type-1 GO:0006810|GO:0016020 RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 SUPERFAMILY SSF49503 32 167 1.56E-31 T 10-03-2017 IPR008972 Cupredoxin RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 Pfam PF07732 Multicopper oxidase 55 165 2.7E-31 T 10-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 SUPERFAMILY SSF49503 172 288 1.71E-32 T 10-03-2017 IPR008972 Cupredoxin RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 SUPERFAMILY SSF49503 374 396 1.71E-32 T 10-03-2017 IPR008972 Cupredoxin RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 Gene3D G3DSA:2.60.40.420 352 516 1.4E-31 T 10-03-2017 IPR008972 Cupredoxin RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 Gene3D G3DSA:2.60.40.420 171 320 3.3E-31 T 10-03-2017 IPR008972 Cupredoxin RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 Pfam PF07731 Multicopper oxidase 402 516 8.4E-24 T 10-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 SUPERFAMILY SSF49503 348 516 1.93E-31 T 10-03-2017 IPR008972 Cupredoxin RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 ProSitePatterns PS00080 Multicopper oxidases signature 2. 499 510 - T 10-03-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 Pfam PF00394 Multicopper oxidase 227 292 1.9E-5 T 10-03-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 RG49_RS11235 256a9cc58f2e51104f7472d20ae27caa 516 Gene3D G3DSA:2.60.40.420 33 170 3.7E-34 T 10-03-2017 IPR008972 Cupredoxin RG49_RS21190 c29a6232dffab8a19396606b55d2b641 484 Gene3D G3DSA:3.30.465.10 108 225 9.4E-30 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS21190 c29a6232dffab8a19396606b55d2b641 484 Pfam PF02913 FAD linked oxidases, C-terminal domain 229 478 2.4E-18 T 10-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 RG49_RS21190 c29a6232dffab8a19396606b55d2b641 484 Pfam PF01565 FAD binding domain 51 190 2.1E-34 T 10-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 RG49_RS21190 c29a6232dffab8a19396606b55d2b641 484 SUPERFAMILY SSF55103 204 481 1.44E-24 T 10-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 RG49_RS21190 c29a6232dffab8a19396606b55d2b641 484 SUPERFAMILY SSF56176 6 225 1.78E-47 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS21190 c29a6232dffab8a19396606b55d2b641 484 Gene3D G3DSA:3.30.43.10 6 107 5.4E-16 T 10-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 RG49_RS21190 c29a6232dffab8a19396606b55d2b641 484 Gene3D G3DSA:1.10.45.10 454 477 4.1E-4 T 10-03-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 Gene3D G3DSA:2.60.420.10 663 732 4.3E-23 T 10-03-2017 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 SUPERFAMILY SSF48208 250 720 2.13E-106 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 298 677 2.9E-154 T 10-03-2017 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 Gene3D G3DSA:1.50.10.10 294 662 7.6E-125 T 10-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 681 729 1.9E-10 T 10-03-2017 IPR005194 Glycoside hydrolase family 65, C-terminal RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 Gene3D G3DSA:2.70.98.40 4 241 5.1E-64 T 10-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 SUPERFAMILY SSF74650 6 240 1.32E-53 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 9 237 4.4E-49 T 10-03-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 RG49_RS03960 a8dfcf07490a695b725b433fce6a1580 755 PIRSF PIRSF036289 1 741 1.2E-233 T 10-03-2017 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 Pfam PF00106 short chain dehydrogenase 9 194 2.0E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.2E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.2E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.2E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.2E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.2E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 Hamap MF_01647 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase [hcaB]. 1 270 63.669 T 10-03-2017 IPR023643 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase HcaB GO:0016491|GO:0055114 KEGG: 00360+1.3.1.87|MetaCyc: PWY-6690 RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.9E-5 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.9E-5 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 SUPERFAMILY SSF51735 2 258 3.33E-52 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22365 e9714f88a73655d115d4e235c9793be8 270 Gene3D G3DSA:3.40.50.720 3 258 2.2E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11675 73231742ed06a56bf11d1a520f4320ab 405 SUPERFAMILY SSF89796 5 401 1.05E-100 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS11675 73231742ed06a56bf11d1a520f4320ab 405 Hamap MF_01050 L-carnitine CoA-transferase [caiB]. 1 405 100.317 T 10-03-2017 IPR023452 L-carnitine CoA-transferase CaiB GO:0009437|GO:0016782 RG49_RS11675 73231742ed06a56bf11d1a520f4320ab 405 Pfam PF02515 CoA-transferase family III 12 378 5.5E-95 T 10-03-2017 IPR003673 CoA-transferase family III GO:0003824 RG49_RS11675 73231742ed06a56bf11d1a520f4320ab 405 Gene3D G3DSA:3.40.50.10540 311 401 3.4E-77 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS11675 73231742ed06a56bf11d1a520f4320ab 405 Gene3D G3DSA:3.40.50.10540 9 216 3.4E-77 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS11675 73231742ed06a56bf11d1a520f4320ab 405 Gene3D G3DSA:3.30.1540.10 228 310 5.3E-6 T 10-03-2017 RG49_RS17480 a4e5053404c27ba8fd78356a73604cae 797 Gene3D G3DSA:3.40.50.2000 7 462 5.1E-184 T 10-03-2017 RG49_RS17480 a4e5053404c27ba8fd78356a73604cae 797 Pfam PF00343 Carbohydrate phosphorylase 93 794 0.0 T 10-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17480 a4e5053404c27ba8fd78356a73604cae 797 SUPERFAMILY SSF53756 8 795 6.12E-296 T 10-03-2017 RG49_RS17480 a4e5053404c27ba8fd78356a73604cae 797 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 9 794 0.0 T 10-03-2017 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17480 a4e5053404c27ba8fd78356a73604cae 797 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 638 650 - T 10-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17480 a4e5053404c27ba8fd78356a73604cae 797 PIRSF PIRSF000460 1 797 9.4E-206 T 10-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17480 a4e5053404c27ba8fd78356a73604cae 797 Gene3D G3DSA:3.40.50.2000 463 780 2.1E-135 T 10-03-2017 RG49_RS22650 505ef700648e78f99388df919615c412 345 Gene3D G3DSA:3.30.1330.10 22 170 3.0E-62 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS22650 505ef700648e78f99388df919615c412 345 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 344 47.078 T 10-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS22650 505ef700648e78f99388df919615c412 345 SUPERFAMILY SSF56042 171 342 5.98E-65 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS22650 505ef700648e78f99388df919615c412 345 SUPERFAMILY SSF55326 7 170 1.11E-52 T 10-03-2017 RG49_RS22650 505ef700648e78f99388df919615c412 345 Gene3D G3DSA:3.90.650.10 171 343 1.7E-69 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS22650 505ef700648e78f99388df919615c412 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 164 2.4E-15 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS22650 505ef700648e78f99388df919615c412 345 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 335 1.6E-155 T 10-03-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS22650 505ef700648e78f99388df919615c412 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 341 4.4E-40 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 SUPERFAMILY SSF46565 1 93 2.36E-27 T 10-03-2017 IPR001623 DnaJ domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 SUPERFAMILY SSF49493 204 284 1.7E-17 T 10-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 Gene3D G3DSA:2.60.260.20 201 276 5.9E-17 T 10-03-2017 RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 Pfam PF01556 DnaJ C terminal domain 120 276 6.7E-34 T 10-03-2017 IPR002939 Chaperone DnaJ, C-terminal RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 10-03-2017 IPR018253 DnaJ domain, conserved site RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 Hamap MF_01154 Curved DNA-binding protein [cbpA]. 1 306 57.426 T 10-03-2017 IPR023859 DNA-binding protein, curved-DNA RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 SUPERFAMILY SSF49493 115 210 1.7E-15 T 10-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 Pfam PF00226 DnaJ domain 5 66 1.9E-23 T 10-03-2017 IPR001623 DnaJ domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 SMART SM00271 4 61 3.0E-26 T 10-03-2017 IPR001623 DnaJ domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 Gene3D G3DSA:1.10.287.110 2 105 1.9E-28 T 10-03-2017 IPR001623 DnaJ domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 Gene3D G3DSA:2.60.260.20 110 199 2.5E-16 T 10-03-2017 RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 PRINTS PR00625 DnaJ domain signature 41 61 2.4E-17 T 10-03-2017 IPR001623 DnaJ domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 PRINTS PR00625 DnaJ domain signature 61 80 2.4E-17 T 10-03-2017 IPR001623 DnaJ domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 PRINTS PR00625 DnaJ domain signature 25 40 2.4E-17 T 10-03-2017 IPR001623 DnaJ domain RG49_RS05700 603148ec4d7d4becda063da63c3730d0 306 PRINTS PR00625 DnaJ domain signature 7 25 2.4E-17 T 10-03-2017 IPR001623 DnaJ domain RG49_RS12675 d14ba95667ec939b3c82f5d87a3b9a28 128 Pfam PF01042 Endoribonuclease L-PSP 7 126 2.0E-45 T 10-03-2017 IPR006175 YjgF/YER057c/UK114 family RG49_RS12675 d14ba95667ec939b3c82f5d87a3b9a28 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 126 7.7E-54 T 10-03-2017 IPR006056 RidA family RG49_RS12675 d14ba95667ec939b3c82f5d87a3b9a28 128 SUPERFAMILY SSF55298 4 127 6.28E-44 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS12675 d14ba95667ec939b3c82f5d87a3b9a28 128 Gene3D G3DSA:3.30.1330.40 3 127 2.8E-47 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS12675 d14ba95667ec939b3c82f5d87a3b9a28 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 10-03-2017 IPR019897 RidA, conserved site RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 2 235 2.0E-65 T 10-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 30.11 T 10-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 Gene3D G3DSA:3.30.1270.10 210 236 5.3E-33 T 10-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 Gene3D G3DSA:3.30.1270.10 82 131 5.3E-33 T 10-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 Gene3D G3DSA:1.10.10.200 2 77 4.8E-28 T 10-03-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 56.792 T 10-03-2017 IPR026562 Probable transcriptional regulatory protein YeeN RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 Pfam PF01709 Transcriptional regulator 4 235 7.1E-78 T 10-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 Gene3D G3DSA:3.30.70.980 132 202 6.6E-22 T 10-03-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS25355 e7bcf29ce39f635ca95eb5a76ffeb3fa 238 SUPERFAMILY SSF75625 2 235 3.4E-77 T 10-03-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 62 207 1.6E-28 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 45 1.1E-6 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 Gene3D G3DSA:3.40.50.700 49 226 1.7E-56 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 227 308 1.4E-31 T 10-03-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 284 297 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 214 231 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 232 250 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 256 282 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 159 183 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 188 211 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 116 139 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 47 69 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 70 94 1.0E-118 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 SUPERFAMILY SSF56770 46 310 6.54E-87 T 10-03-2017 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 2 360 7.2E-204 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 Gene3D G3DSA:4.10.480.10 227 310 1.6E-38 T 10-03-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal RG49_RS05850 dc8ab3c05eace93812417bcdcbf160b7 372 PIRSF PIRSF000310 5 357 2.8E-146 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 ProSitePatterns PS00801 Transketolase signature 1. 11 31 - T 10-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 SUPERFAMILY SSF52518 4 320 3.48E-120 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 TIGRFAM TIGR00232 tktlase_bact: transketolase 4 662 0.0 T 10-03-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 Pfam PF02779 Transketolase, pyrimidine binding domain 353 523 2.4E-46 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 3 333 1.2E-172 T 10-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 Gene3D G3DSA:3.40.50.970 326 532 1.2E-79 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 10-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 SMART SM00861 354 524 2.5E-66 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 SUPERFAMILY SSF52518 332 525 4.26E-68 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 Gene3D G3DSA:3.40.50.920 537 662 2.3E-49 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 SUPERFAMILY SSF52922 532 663 1.57E-43 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 Pfam PF02780 Transketolase, C-terminal domain 539 654 2.2E-20 T 10-03-2017 IPR033248 Transketolase, C-terminal domain RG49_RS22845 764ab033a4f56e547067b601a3c64ab2 667 Gene3D G3DSA:3.40.50.970 4 320 2.6E-132 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS07880 e108322e83f3bd05731fd70192ae503a 235 Pfam PF06889 Protein of unknown function (DUF1266) 41 216 5.9E-41 T 10-03-2017 IPR009677 Protein of unknown function DUF1266 RG49_RS13490 a2707019634b6c87a15d2c61490557ff 252 Pfam PF00005 ABC transporter 22 173 1.1E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS13490 a2707019634b6c87a15d2c61490557ff 252 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 3 250 4.0E-124 T 10-03-2017 IPR012700 Phosphonate C-P lyase system, PhnK RG49_RS13490 a2707019634b6c87a15d2c61490557ff 252 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS13490 a2707019634b6c87a15d2c61490557ff 252 SMART SM00382 30 223 6.4E-15 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS13490 a2707019634b6c87a15d2c61490557ff 252 SUPERFAMILY SSF52540 3 248 8.1E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13490 a2707019634b6c87a15d2c61490557ff 252 Gene3D G3DSA:3.40.50.300 4 247 2.7E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13490 a2707019634b6c87a15d2c61490557ff 252 PIRSF PIRSF037116 1 252 4.0E-141 T 10-03-2017 IPR012700 Phosphonate C-P lyase system, PhnK RG49_RS20145 fb8570c0e78a414e59aca3a077fd1ffa 187 SUPERFAMILY SSF143456 1 187 4.84E-66 T 10-03-2017 RG49_RS20145 fb8570c0e78a414e59aca3a077fd1ffa 187 Gene3D G3DSA:3.40.1740.10 131 177 7.9E-36 T 10-03-2017 RG49_RS20145 fb8570c0e78a414e59aca3a077fd1ffa 187 Gene3D G3DSA:3.40.1740.10 2 40 7.9E-36 T 10-03-2017 RG49_RS20145 fb8570c0e78a414e59aca3a077fd1ffa 187 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 1 187 39.617 T 10-03-2017 IPR003774 Protein of unknown function UPF0301 RG49_RS20145 fb8570c0e78a414e59aca3a077fd1ffa 187 Gene3D G3DSA:3.30.70.1300 41 130 7.3E-29 T 10-03-2017 RG49_RS20145 fb8570c0e78a414e59aca3a077fd1ffa 187 Pfam PF02622 Uncharacterized ACR, COG1678 12 174 9.9E-50 T 10-03-2017 IPR003774 Protein of unknown function UPF0301 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 Pfam PF01817 Chorismate mutase type II 11 89 5.9E-17 T 10-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 SUPERFAMILY SSF55021 280 377 1.83E-22 T 10-03-2017 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 Gene3D G3DSA:3.30.70.260 294 378 4.9E-26 T 10-03-2017 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 TIGRFAM TIGR01797 CM_P_1: chorismate mutase 7 89 8.9E-42 T 10-03-2017 IPR010952 Chorismate mutase, gammaproteobacteria GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 PIRSF PIRSF001500 1 380 9.0E-146 T 10-03-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 SUPERFAMILY SSF48600 6 93 1.41E-22 T 10-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 Gene3D G3DSA:3.40.190.10 194 268 2.9E-28 T 10-03-2017 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 SUPERFAMILY SSF53850 105 291 2.39E-55 T 10-03-2017 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 Gene3D G3DSA:3.40.190.10 107 193 5.8E-33 T 10-03-2017 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 Gene3D G3DSA:1.20.59.10 1 106 5.2E-46 T 10-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 261 283 - T 10-03-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 325 332 - T 10-03-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 SMART SM00830 11 91 1.0E-24 T 10-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22035 d3e39be20748e172df99818375e5108c 386 Pfam PF00800 Prephenate dehydratase 106 286 4.1E-61 T 10-03-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 Hamap MF_01856 Ribosomal RNA small subunit methyltransferase B [rsmB]. 1 429 74.576 T 10-03-2017 IPR023541 rRNA small subunit methyltransferase B, enterobacteriaceae GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 Pfam PF01029 NusB family 6 127 1.9E-25 T 10-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 SUPERFAMILY SSF48013 5 149 5.07E-36 T 10-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 Gene3D G3DSA:3.30.70.1170 173 230 2.6E-28 T 10-03-2017 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 Gene3D G3DSA:3.40.50.150 233 429 2.9E-56 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 SUPERFAMILY SSF53335 142 429 1.05E-76 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 8 429 4.5E-197 T 10-03-2017 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 316 327 - T 10-03-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 Gene3D G3DSA:1.10.287.730 148 172 5.9E-18 T 10-03-2017 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 222 236 2.5E-31 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 411 428 2.5E-31 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 329 2.5E-31 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 251 261 2.5E-31 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 367 383 2.5E-31 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 Gene3D G3DSA:1.10.940.10 2 147 7.3E-49 T 10-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 RG49_RS18160 8b7a837eef5a8ef62c5f207f8acd54c0 429 Pfam PF01189 16S rRNA methyltransferase RsmB/F 239 426 1.6E-80 T 10-03-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS21790 030025e27b861f6a6c3880a608a96b9b 422 Gene3D G3DSA:3.30.9.10 86 137 7.0E-11 T 10-03-2017 RG49_RS21790 030025e27b861f6a6c3880a608a96b9b 422 Gene3D G3DSA:3.30.9.10 206 228 7.0E-11 T 10-03-2017 RG49_RS21790 030025e27b861f6a6c3880a608a96b9b 422 Hamap MF_00990 L-2-hydroxyglutarate oxidase LhgO [lhgO]. 1 422 86.866 T 10-03-2017 IPR030862 L-2-hydroxyglutarate oxidase LhgO GO:0034419 KEGG: 00630+1.1.3.15|MetaCyc: PWY-181 RG49_RS21790 030025e27b861f6a6c3880a608a96b9b 422 Gene3D G3DSA:3.50.50.60 138 205 1.9E-33 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21790 030025e27b861f6a6c3880a608a96b9b 422 Gene3D G3DSA:3.50.50.60 1 84 1.9E-33 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21790 030025e27b861f6a6c3880a608a96b9b 422 Pfam PF01266 FAD dependent oxidoreductase 3 390 4.8E-75 T 10-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 RG49_RS21790 030025e27b861f6a6c3880a608a96b9b 422 SUPERFAMILY SSF51905 1 286 4.75E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS01270 52042560d01a75e54a9ff1b7bc414723 447 TIGRFAM TIGR03241 arg_catab_astB: succinylarginine dihydrolase 3 440 8.1E-244 T 10-03-2017 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 RG49_RS01270 52042560d01a75e54a9ff1b7bc414723 447 Pfam PF04996 Succinylarginine dihydrolase 3 440 2.3E-213 T 10-03-2017 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 RG49_RS01270 52042560d01a75e54a9ff1b7bc414723 447 SUPERFAMILY SSF55909 3 441 1.0E-204 T 10-03-2017 RG49_RS01270 52042560d01a75e54a9ff1b7bc414723 447 Hamap MF_01172 N-succinylarginine dihydrolase [astB]. 1 441 58.948 T 10-03-2017 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 RG49_RS01270 52042560d01a75e54a9ff1b7bc414723 447 Gene3D G3DSA:3.75.10.20 1 445 5.8E-236 T 10-03-2017 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 SUPERFAMILY SSF55315 2 76 5.18E-21 T 10-03-2017 IPR029064 50S ribosomal protein L30e-like RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 SUPERFAMILY SSF75217 68 242 3.2E-49 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 Pfam PF00588 SpoU rRNA Methylase family 96 236 1.5E-40 T 10-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 77 1.5E-18 T 10-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 1 242 9.3E-95 T 10-03-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 Gene3D G3DSA:3.30.1330.30 1 76 1.5E-27 T 10-03-2017 IPR029064 50S ribosomal protein L30e-like RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 2 243 44.502 T 10-03-2017 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 Gene3D G3DSA:3.40.1280.10 93 242 1.2E-54 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS13015 408cf5369cfd018aab68e18204ca5547 243 SMART SM00967 4 80 3.9E-21 T 10-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 RG49_RS07185 b0c5d722fd1a022bbc75f83eab1717c7 477 PIRSF PIRSF002457 1 474 8.7E-151 T 10-03-2017 IPR030676 Citrate carrier CitT-related RG49_RS07185 b0c5d722fd1a022bbc75f83eab1717c7 477 Pfam PF00939 Sodium:sulfate symporter transmembrane region 4 474 7.2E-183 T 10-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 RG49_RS07185 b0c5d722fd1a022bbc75f83eab1717c7 477 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 23 468 2.1E-166 T 10-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 RG49_RS13595 d337d6452a6bceb240d4abc16dba8151 139 Pfam PF00384 Molybdopterin oxidoreductase 61 138 1.3E-19 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS13595 d337d6452a6bceb240d4abc16dba8151 139 Gene3D G3DSA:2.20.25.90 1 54 1.7E-21 T 10-03-2017 RG49_RS13595 d337d6452a6bceb240d4abc16dba8151 139 Gene3D G3DSA:3.40.50.740 61 136 3.0E-27 T 10-03-2017 RG49_RS13595 d337d6452a6bceb240d4abc16dba8151 139 SUPERFAMILY SSF53706 1 139 6.54E-51 T 10-03-2017 RG49_RS13595 d337d6452a6bceb240d4abc16dba8151 139 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 6 23 - T 10-03-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 RG49_RS13595 d337d6452a6bceb240d4abc16dba8151 139 SMART SM00926 1 54 8.1E-17 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS13595 d337d6452a6bceb240d4abc16dba8151 139 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 53 2.0E-16 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05410 5c3518d48a4b5d79352a29fbe0fa98b6 511 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 23 507 5.4E-201 T 10-03-2017 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 RG49_RS05410 5c3518d48a4b5d79352a29fbe0fa98b6 511 PIRSF PIRSF006281 1 511 4.7E-243 T 10-03-2017 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D RG49_RS05410 5c3518d48a4b5d79352a29fbe0fa98b6 511 SUPERFAMILY SSF81296 397 510 5.32E-34 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS05410 5c3518d48a4b5d79352a29fbe0fa98b6 511 Hamap MF_01069 Glucans biosynthesis protein G [mdoG]. 6 509 63.958 T 10-03-2017 IPR023704 Glucan biosynthesis protein G RG49_RS05410 5c3518d48a4b5d79352a29fbe0fa98b6 511 SUPERFAMILY SSF74650 23 393 4.08E-166 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS05410 5c3518d48a4b5d79352a29fbe0fa98b6 511 Gene3D G3DSA:2.70.98.10 22 395 3.6E-177 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS05410 5c3518d48a4b5d79352a29fbe0fa98b6 511 Gene3D G3DSA:2.60.40.10 399 510 1.2E-43 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS01820 0e5e79711e0e84c660a564e4fae7fd6e 670 Pfam PF04632 Fusaric acid resistance protein family 20 662 2.6E-175 T 10-03-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 256 329 2.0E-36 T 10-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 308 6.0E-24 T 10-03-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 Gene3D G3DSA:1.10.150.20 244 328 6.1E-38 T 10-03-2017 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF47789 251 325 1.27E-25 T 10-03-2017 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF56553 53 178 1.45E-41 T 10-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 156 1.6E-23 T 10-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 317 34.651 T 10-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 228 3.9E-24 T 10-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 Gene3D G3DSA:3.30.1360.10 9 57 1.5E-10 T 10-03-2017 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 SMART SM00662 23 234 3.0E-105 T 10-03-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 316 4.3E-113 T 10-03-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF55257 179 231 1.57E-30 T 10-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF55257 6 53 1.57E-30 T 10-03-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS18125 456bfd9236c5cfd90803aed14a8ec2d0 329 Gene3D G3DSA:2.170.120.12 58 177 5.0E-40 T 10-03-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS12370 bf824eb5e615c18a36f1c37d4f89d092 130 Pfam PF04965 Gene 25-like lysozyme 21 105 2.4E-11 T 10-03-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD RG49_RS12370 bf824eb5e615c18a36f1c37d4f89d092 130 Gene3D G3DSA:3.10.450.40 60 114 0.001 T 10-03-2017 RG49_RS12370 bf824eb5e615c18a36f1c37d4f89d092 130 Hamap MF_02010 Anti-adapter protein IraD [iraD]. 1 122 37.412 T 10-03-2017 IPR023776 Anti-adapter protein, IraD GO:0006974|GO:0043856 RG49_RS12370 bf824eb5e615c18a36f1c37d4f89d092 130 SUPERFAMILY SSF160719 22 112 6.15E-7 T 10-03-2017 RG49_RS02120 87b32fe0a9126a345fd5dd213ff708f5 204 Hamap MF_00940 Tat proofreading chaperone DmsD [dmsD]. 5 204 41.957 T 10-03-2017 IPR028611 Tat proofreading chaperone DmsD GO:0005048 RG49_RS02120 87b32fe0a9126a345fd5dd213ff708f5 204 Pfam PF02613 Nitrate reductase delta subunit 51 163 2.1E-23 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS02120 87b32fe0a9126a345fd5dd213ff708f5 204 SUPERFAMILY SSF89155 3 200 6.41E-58 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS02120 87b32fe0a9126a345fd5dd213ff708f5 204 PIRSF PIRSF004690 2 204 1.2E-63 T 10-03-2017 IPR026269 Tat proofreading chaperone DmsD-type RG49_RS02120 87b32fe0a9126a345fd5dd213ff708f5 204 Gene3D G3DSA:1.10.3480.10 4 204 2.7E-62 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS08685 677dcd5545f1f8a54d803b6efc570355 159 Gene3D G3DSA:3.90.960.10 1 157 4.0E-62 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS08685 677dcd5545f1f8a54d803b6efc570355 159 PIRSF PIRSF006181 1 159 4.5E-60 T 10-03-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC RG49_RS08685 677dcd5545f1f8a54d803b6efc570355 159 SUPERFAMILY SSF55826 2 155 1.2E-45 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS08685 677dcd5545f1f8a54d803b6efc570355 159 Pfam PF04073 Aminoacyl-tRNA editing domain 31 146 4.6E-23 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS08685 677dcd5545f1f8a54d803b6efc570355 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 156 9.6E-58 T 10-03-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 Pfam PF00270 DEAD/DEAH box helicase 28 197 6.7E-47 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 SUPERFAMILY SSF52540 76 358 1.14E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 Pfam PF00271 Helicase conserved C-terminal domain 236 343 3.0E-28 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 Gene3D G3DSA:3.40.50.300 3 214 2.0E-75 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 Hamap MF_00967 ATP-dependent RNA helicase SrmB [srmB]. 4 428 50.549 T 10-03-2017 IPR028621 ATP-dependent RNA helicase SrmB GO:0000027|GO:0004004 RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 SMART SM00490 262 343 7.5E-31 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 Gene3D G3DSA:3.40.50.300 215 374 1.7E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 10-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site RG49_RS22155 8558663f9e2beb6bb3074c54d3e213ba 444 SMART SM00487 23 223 6.8E-60 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS06885 b75dc7ec0c93952cb1b3e306aeae6a9a 299 PIRSF PIRSF000371 1 298 7.4E-93 T 10-03-2017 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 RG49_RS06885 b75dc7ec0c93952cb1b3e306aeae6a9a 299 SUPERFAMILY SSF102114 123 267 1.96E-14 T 10-03-2017 RG49_RS06885 b75dc7ec0c93952cb1b3e306aeae6a9a 299 Pfam PF13353 4Fe-4S single cluster domain 12 153 7.0E-10 T 10-03-2017 RG49_RS06885 b75dc7ec0c93952cb1b3e306aeae6a9a 299 Pfam PF04055 Radical SAM superfamily 19 229 6.9E-33 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS06885 b75dc7ec0c93952cb1b3e306aeae6a9a 299 Gene3D G3DSA:3.80.30.10 122 297 6.6E-55 T 10-03-2017 RG49_RS06885 b75dc7ec0c93952cb1b3e306aeae6a9a 299 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 2 292 1.8E-111 T 10-03-2017 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 RG49_RS06885 b75dc7ec0c93952cb1b3e306aeae6a9a 299 ProSitePatterns PS01087 Radical activating enzymes signature. 13 34 - T 10-03-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Gene3D G3DSA:3.40.50.620 364 571 8.2E-142 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Gene3D G3DSA:3.40.50.620 3 193 8.2E-142 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Gene3D G3DSA:3.40.50.620 609 630 8.2E-142 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 932 0.0 T 10-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Gene3D G3DSA:3.90.740.10 194 360 4.9E-48 T 10-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Gene3D G3DSA:1.10.287.380 878 933 7.4E-6 T 10-03-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 949 16.2 T 10-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Gene3D G3DSA:1.10.730.10 631 816 5.4E-65 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 886 944 4.9E-16 T 10-03-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 SUPERFAMILY SSF47323 642 899 1.87E-70 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Pfam PF08264 Anticodon-binding domain of tRNA 674 824 4.3E-42 T 10-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 631 1.0E-228 T 10-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 SUPERFAMILY SSF50677 191 365 5.23E-57 T 10-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 PRINTS PR00986 Valyl-tRNA synthetase signature 469 490 1.7E-35 T 10-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 PRINTS PR00986 Valyl-tRNA synthetase signature 35 46 1.7E-35 T 10-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.7E-35 T 10-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 PRINTS PR00986 Valyl-tRNA synthetase signature 500 518 1.7E-35 T 10-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 PRINTS PR00986 Valyl-tRNA synthetase signature 369 382 1.7E-35 T 10-03-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 SUPERFAMILY SSF52374 364 571 4.38E-137 T 10-03-2017 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 SUPERFAMILY SSF52374 1 192 4.38E-137 T 10-03-2017 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 SUPERFAMILY SSF52374 609 641 4.38E-137 T 10-03-2017 RG49_RS12605 cccf53b06d86467b3450058308f2eb58 951 SUPERFAMILY SSF46589 884 947 6.8E-16 T 10-03-2017 IPR010978 tRNA-binding arm GO:0000166 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 454 3.1E-19 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 Pfam PF00672 HAMP domain 165 234 6.1E-13 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 SMART SM00387 345 455 3.9E-33 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 Pfam PF16527 Two-component sensor protein CpxA, periplasmic domain 82 146 1.9E-10 T 10-03-2017 IPR032404 Two-component sensor protein CpxA, periplasmic domain RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 SMART SM00304 184 237 1.1E-9 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 2.4E-15 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 2.4E-15 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 2.4E-15 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 2.4E-15 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 SUPERFAMILY SSF47384 224 299 3.53E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 Gene3D G3DSA:1.10.287.130 228 285 8.8E-18 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 SMART SM00388 238 300 1.4E-15 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 Gene3D G3DSA:3.30.565.10 286 454 3.4E-39 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 299 2.5E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14580 2ce30b4178fd6c01796b6877cfc322e1 457 SUPERFAMILY SSF55874 289 453 2.62E-38 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 10-03-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 Gene3D G3DSA:3.40.430.10 1 159 4.4E-59 T 10-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 PIRSF PIRSF000194 1 159 5.7E-57 T 10-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 SUPERFAMILY SSF53597 1 159 1.07E-55 T 10-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 PRINTS PR00070 Dihydrofolate reductase signature 27 35 8.5E-15 T 10-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 PRINTS PR00070 Dihydrofolate reductase signature 90 104 8.5E-15 T 10-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 PRINTS PR00070 Dihydrofolate reductase signature 40 51 8.5E-15 T 10-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 PRINTS PR00070 Dihydrofolate reductase signature 13 23 8.5E-15 T 10-03-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 RG49_RS11625 ce7c49af8b85e648e2e76cb6d1771f09 159 Pfam PF00186 Dihydrofolate reductase 1 158 3.4E-58 T 10-03-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Gene3D G3DSA:3.30.310.50 375 455 1.0E-17 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 SUPERFAMILY SSF53738 263 368 6.67E-34 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Gene3D G3DSA:3.40.120.10 6 149 5.2E-36 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 131 6.3E-32 T 10-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 92 101 - T 10-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 SUPERFAMILY SSF53738 153 261 5.1E-28 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 4.8E-32 T 10-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 4.8E-32 T 10-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 4.8E-32 T 10-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 209 222 4.8E-32 T 10-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Gene3D G3DSA:3.40.120.10 255 368 1.6E-42 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 SUPERFAMILY SSF55957 374 456 5.23E-18 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 445 2.9E-9 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 372 2.5E-26 T 10-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 SUPERFAMILY SSF53738 4 176 1.37E-38 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 154 258 4.9E-22 T 10-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS24945 78e5733de232f0d6d5640009f1caf4ec 456 Gene3D G3DSA:3.40.120.10 172 254 5.8E-28 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 Gene3D G3DSA:3.40.50.2300 2 88 1.7E-7 T 10-03-2017 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 Pfam PF00196 Bacterial regulatory proteins, luxR family 84 138 4.4E-22 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 SMART SM00421 82 139 3.4E-23 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 Gene3D G3DSA:1.10.10.10 89 144 4.6E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 SUPERFAMILY SSF46894 69 144 1.8E-22 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 SUPERFAMILY SSF52172 2 69 6.49E-6 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 99 115 1.2E-15 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 85 99 1.2E-15 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 115 127 1.2E-15 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS20715 f67fad3d8b42c0dec58e916fe6374dc8 147 ProSitePatterns PS00622 LuxR-type HTH domain signature. 99 126 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 105 122 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 Gene3D G3DSA:2.60.40.360 29 147 2.6E-43 T 10-03-2017 IPR008962 PapD-like RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 SUPERFAMILY SSF49584 155 242 1.11E-22 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 Gene3D G3DSA:2.60.40.1070 152 241 2.1E-26 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 PRINTS PR00969 Pili chaperone signature 76 97 9.8E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 PRINTS PR00969 Pili chaperone signature 30 39 9.8E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 PRINTS PR00969 Pili chaperone signature 166 181 9.8E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 PRINTS PR00969 Pili chaperone signature 106 123 9.8E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 PRINTS PR00969 Pili chaperone signature 129 144 9.8E-30 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 30 147 7.8E-37 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 171 228 1.9E-11 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS23395 1dc380d2eb04952d04c43102aff386a6 250 SUPERFAMILY SSF49354 29 147 2.22E-37 T 10-03-2017 IPR008962 PapD-like RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PRINTS PR01171 Bacterial lipocalin signature 163 173 2.6E-51 T 10-03-2017 IPR002446 Lipocalin, bacterial GO:0005215 RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PRINTS PR01171 Bacterial lipocalin signature 104 118 2.6E-51 T 10-03-2017 IPR002446 Lipocalin, bacterial GO:0005215 RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PRINTS PR01171 Bacterial lipocalin signature 136 147 2.6E-51 T 10-03-2017 IPR002446 Lipocalin, bacterial GO:0005215 RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PRINTS PR01171 Bacterial lipocalin signature 121 129 2.6E-51 T 10-03-2017 IPR002446 Lipocalin, bacterial GO:0005215 RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PRINTS PR01171 Bacterial lipocalin signature 51 67 2.6E-51 T 10-03-2017 IPR002446 Lipocalin, bacterial GO:0005215 RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PRINTS PR01171 Bacterial lipocalin signature 34 48 2.6E-51 T 10-03-2017 IPR002446 Lipocalin, bacterial GO:0005215 RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PRINTS PR01171 Bacterial lipocalin signature 70 79 2.6E-51 T 10-03-2017 IPR002446 Lipocalin, bacterial GO:0005215 RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 ProSitePatterns PS00213 Lipocalin signature. 33 46 - T 10-03-2017 IPR022272 Lipocalin family conserved site RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 Gene3D G3DSA:2.40.128.20 2 175 9.3E-61 T 10-03-2017 IPR012674 Calycin RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 PIRSF PIRSF036893 1 177 3.2E-52 T 10-03-2017 IPR022271 Lipocalin, ApoD type RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 SUPERFAMILY SSF50814 15 176 9.98E-50 T 10-03-2017 IPR011038 Calycin-like RG49_RS13170 642602ef9684aab00daeeae70738fc17 177 Pfam PF08212 Lipocalin-like domain 34 174 1.5E-50 T 10-03-2017 IPR000566 Lipocalin/cytosolic fatty-acid binding domain RG49_RS13820 93f682dc56900629d70acf47473a6500 122 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 70 81 - T 10-03-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 RG49_RS13820 93f682dc56900629d70acf47473a6500 122 Gene3D G3DSA:1.10.3830.10 3 121 2.4E-46 T 10-03-2017 RG49_RS13820 93f682dc56900629d70acf47473a6500 122 Pfam PF01219 Prokaryotic diacylglycerol kinase 16 117 1.2E-35 T 10-03-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 RG49_RS15665 3f21ff6cf1010b05b352686e724f547c 391 Gene3D G3DSA:1.20.1250.20 5 186 1.2E-33 T 10-03-2017 RG49_RS15665 3f21ff6cf1010b05b352686e724f547c 391 Gene3D G3DSA:1.20.1250.20 211 385 3.1E-9 T 10-03-2017 RG49_RS15665 3f21ff6cf1010b05b352686e724f547c 391 SUPERFAMILY SSF103473 3 385 6.93E-56 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15665 3f21ff6cf1010b05b352686e724f547c 391 Hamap MF_01530 Multidrug resistance protein MdtL [mdtL]. 1 391 37.529 T 10-03-2017 IPR023697 Multidrug resistance protein MdtL GO:0005215|GO:0005886 RG49_RS15665 3f21ff6cf1010b05b352686e724f547c 391 Pfam PF07690 Major Facilitator Superfamily 10 342 1.5E-43 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS04615 9339111df5a57673af88135502921e3c 363 Gene3D G3DSA:3.10.20.30 268 363 2.5E-50 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS04615 9339111df5a57673af88135502921e3c 363 SUPERFAMILY SSF52540 3 301 2.56E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04615 9339111df5a57673af88135502921e3c 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 1.4E-39 T 10-03-2017 IPR013029 Domain of unknown function DUF933 RG49_RS04615 9339111df5a57673af88135502921e3c 363 Pfam PF01926 50S ribosome-binding GTPase 5 121 3.4E-21 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 PIRSF PIRSF006641 1 363 5.5E-159 T 10-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 47.077 T 10-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 Gene3D G3DSA:3.40.50.300 201 267 6.8E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04615 9339111df5a57673af88135502921e3c 363 Gene3D G3DSA:3.40.50.300 4 130 6.8E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04615 9339111df5a57673af88135502921e3c 363 Gene3D G3DSA:1.10.150.300 131 200 5.5E-28 T 10-03-2017 IPR023192 TGS-like domain RG49_RS04615 9339111df5a57673af88135502921e3c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.3E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.3E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.3E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.3E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 8.8E-179 T 10-03-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 RG49_RS04615 9339111df5a57673af88135502921e3c 363 SUPERFAMILY SSF81271 279 359 4.14E-36 T 10-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 SUPERFAMILY SSF51735 142 310 7.77E-35 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 SUPERFAMILY SSF50129 11 178 2.28E-48 T 10-03-2017 IPR011032 GroES-like RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 Gene3D G3DSA:3.90.180.10 6 171 3.6E-52 T 10-03-2017 IPR011032 GroES-like RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 SMART SM00829 9 343 6.8E-4 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 Gene3D G3DSA:3.40.50.720 172 288 1.2E-32 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 Pfam PF00107 Zinc-binding dehydrogenase 180 302 2.3E-24 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS01115 c491130a3d1d078bfc78a30733fcceed 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 139 1.6E-29 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 Gene3D G3DSA:1.10.220.30 8 71 7.2E-15 T 10-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 SUPERFAMILY SSF48029 5 104 2.62E-18 T 10-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 247 267 5.8E-75 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 271 297 5.8E-75 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 33 59 5.8E-75 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 114 137 5.8E-75 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 194 219 5.8E-75 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 225 245 5.8E-75 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 4 20 5.8E-75 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 1 331 7.6E-153 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 Gene3D G3DSA:1.10.220.30 194 330 2.3E-40 T 10-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 Gene3D G3DSA:1.10.220.30 74 183 3.3E-28 T 10-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 Pfam PF14841 FliG middle domain 115 186 3.0E-24 T 10-03-2017 IPR032779 Flagellar motor switch protein FliG, middle domain RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 Pfam PF01706 FliG C-terminal domain 218 323 1.4E-37 T 10-03-2017 IPR023087 Flagellar motor switch protein FliG, C-terminal RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 PIRSF PIRSF003161 1 331 2.1E-118 T 10-03-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 SUPERFAMILY SSF48029 115 324 9.55E-63 T 10-03-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical RG49_RS00215 142007a5db6d956b34a72e96db840cdf 331 Pfam PF14842 FliG N-terminal domain 3 103 1.5E-29 T 10-03-2017 IPR028263 Flagellar motor switch protein FliG, N-terminal domain RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 SUPERFAMILY SSF53649 481 536 6.11E-99 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 SUPERFAMILY SSF53649 57 82 6.11E-99 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 SUPERFAMILY SSF53649 109 445 6.11E-99 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 Gene3D G3DSA:3.30.1120.10 423 533 8.1E-7 T 10-03-2017 RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 ProSitePatterns PS00523 Sulfatases signature 1. 130 142 - T 10-03-2017 IPR024607 Sulfatase, conserved site RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 Pfam PF00884 Sulfatase 58 408 8.4E-102 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 Gene3D G3DSA:3.40.720.10 56 422 5.6E-97 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS02830 c604398bf9746ecd834ebe5d93da79ac 560 ProSitePatterns PS00149 Sulfatases signature 2. 175 185 - T 10-03-2017 IPR024607 Sulfatase, conserved site RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Pfam PF02574 Homocysteine S-methyltransferase 17 325 1.5E-91 T 10-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Gene3D G3DSA:3.20.20.20 364 636 1.9E-114 T 10-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Pfam PF02310 B12 binding domain 748 840 3.0E-18 T 10-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 SUPERFAMILY SSF56507 902 1226 4.32E-136 T 10-03-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Pfam PF02607 B12 binding domain 660 733 3.2E-25 T 10-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Gene3D G3DSA:1.10.1240.10 650 737 1.8E-40 T 10-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Gene3D G3DSA:3.20.20.330 3 363 3.6E-128 T 10-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 938 1208 1.1E-127 T 10-03-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 SUPERFAMILY SSF52242 743 894 2.35E-48 T 10-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 SUPERFAMILY SSF82282 7 399 6.02E-119 T 10-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Pfam PF00809 Pterin binding enzyme 360 598 2.1E-62 T 10-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 PIRSF PIRSF000381 1 1195 0.0 T 10-03-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 SMART SM01018 657 740 5.0E-45 T 10-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 TIGRFAM TIGR02082 metH: methionine synthase 12 1192 0.0 T 10-03-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 SUPERFAMILY SSF51717 356 630 1.05E-88 T 10-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 SUPERFAMILY SSF47644 652 739 4.05E-29 T 10-03-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Gene3D G3DSA:3.10.196.10 957 1226 5.8E-117 T 10-03-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS13970 df7f49ccafb6fe8d383c5edf80005153 1227 Gene3D G3DSA:3.40.50.280 745 894 7.4E-66 T 10-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 RG49_RS24330 2797aeecb1239f6e9820f879c10a51ef 312 SUPERFAMILY SSF110581 9 308 1.7E-117 T 10-03-2017 RG49_RS24330 2797aeecb1239f6e9820f879c10a51ef 312 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 15 309 43.961 T 10-03-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 RG49_RS24330 2797aeecb1239f6e9820f879c10a51ef 312 Pfam PF04227 Indigoidine synthase A like protein 16 306 3.7E-131 T 10-03-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 RG49_RS08015 20f397a95735142ebb05825c6c566ddc 226 PIRSF PIRSF006171 3 226 1.5E-77 T 10-03-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 RG49_RS08015 20f397a95735142ebb05825c6c566ddc 226 Pfam PF00072 Response regulator receiver domain 8 117 2.6E-19 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS08015 20f397a95735142ebb05825c6c566ddc 226 Gene3D G3DSA:3.40.50.2300 4 130 2.9E-23 T 10-03-2017 RG49_RS08015 20f397a95735142ebb05825c6c566ddc 226 Pfam PF12431 Transcriptional regulator 135 160 1.7E-8 T 10-03-2017 IPR028141 Transcriptional regulator RG49_RS08015 20f397a95735142ebb05825c6c566ddc 226 SUPERFAMILY SSF52172 4 179 4.7E-29 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS08015 20f397a95735142ebb05825c6c566ddc 226 SMART SM00448 5 118 9.6E-21 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS03935 d7417224c85440ccbd03f55745bc8c2f 465 PIRSF PIRSF019381 1 465 8.2E-215 T 10-03-2017 IPR007413 Protein of unknown function DUF463, YcjX-like protein RG49_RS03935 d7417224c85440ccbd03f55745bc8c2f 465 Pfam PF04317 YcjX-like family, DUF463 20 464 1.4E-183 T 10-03-2017 IPR007413 Protein of unknown function DUF463, YcjX-like protein RG49_RS00160 6ae14d3cc495dafaede0cc8dc32b1d5a 261 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 14 255 2.5E-82 T 10-03-2017 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 RG49_RS00160 6ae14d3cc495dafaede0cc8dc32b1d5a 261 Pfam PF01311 Bacterial export proteins, family 1 14 247 8.3E-69 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS00160 6ae14d3cc495dafaede0cc8dc32b1d5a 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.4E-33 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS00160 6ae14d3cc495dafaede0cc8dc32b1d5a 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 80 99 1.4E-33 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS00160 6ae14d3cc495dafaede0cc8dc32b1d5a 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 1.4E-33 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS00160 6ae14d3cc495dafaede0cc8dc32b1d5a 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 1.4E-33 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS12435 dd0cb5c7b3e094503a3bfb7e9b0ce1f3 182 SUPERFAMILY SSF49401 32 182 1.34E-36 T 10-03-2017 IPR008966 Adhesion domain RG49_RS12435 dd0cb5c7b3e094503a3bfb7e9b0ce1f3 182 Gene3D G3DSA:2.60.40.1090 31 182 6.2E-44 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12435 dd0cb5c7b3e094503a3bfb7e9b0ce1f3 182 Pfam PF00419 Fimbrial protein 33 182 6.0E-23 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 PRINTS PR00421 Thioredoxin family signature 55 63 1.7E-9 T 10-03-2017 RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 PRINTS PR00421 Thioredoxin family signature 103 114 1.7E-9 T 10-03-2017 RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 PRINTS PR00421 Thioredoxin family signature 63 72 1.7E-9 T 10-03-2017 RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 Pfam PF00085 Thioredoxin 37 137 1.6E-28 T 10-03-2017 IPR013766 Thioredoxin domain GO:0045454 RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 10-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 TIGRFAM TIGR01068 thioredoxin: thioredoxin 45 138 4.5E-37 T 10-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 SUPERFAMILY SSF52833 24 138 2.0E-38 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS22125 e9d50cfbfaea17e8ebb59f9add77f07a 139 Gene3D G3DSA:3.40.30.10 31 138 8.1E-37 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS20290 cc7523a7f047592be94e1210abeed74e 492 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 4 490 3.7E-227 T 10-03-2017 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 RG49_RS20290 cc7523a7f047592be94e1210abeed74e 492 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 317 461 6.6E-41 T 10-03-2017 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain RG49_RS20290 cc7523a7f047592be94e1210abeed74e 492 SUPERFAMILY SSF100950 226 490 6.2E-71 T 10-03-2017 RG49_RS20290 cc7523a7f047592be94e1210abeed74e 492 Gene3D G3DSA:3.40.1080.10 8 218 1.6E-39 T 10-03-2017 RG49_RS20290 cc7523a7f047592be94e1210abeed74e 492 SUPERFAMILY SSF100950 7 219 1.75E-59 T 10-03-2017 RG49_RS20290 cc7523a7f047592be94e1210abeed74e 492 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 1 213 3.8E-76 T 10-03-2017 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 RG49_RS20290 cc7523a7f047592be94e1210abeed74e 492 Gene3D G3DSA:3.40.810.20 224 484 9.0E-72 T 10-03-2017 RG49_RS05940 5e6a0c788d0c833da07e1ed249e16d3e 150 ProDom PD033720 UPF0268 YCBG DEHYDROGENASE PM0482 PBPRA1775 PLU1774 YPO1433/Y2737/YP0877 VV1664 HI1323 HD0178 1 131 3.0E-72 T 10-03-2017 IPR009390 Macrodomain Ter protein, MatP GO:0043565 RG49_RS05940 5e6a0c788d0c833da07e1ed249e16d3e 150 Pfam PF06303 Organiser of macrodomain of Terminus of chromosome 1 147 4.9E-75 T 10-03-2017 IPR009390 Macrodomain Ter protein, MatP GO:0043565 RG49_RS05940 5e6a0c788d0c833da07e1ed249e16d3e 150 Hamap MF_01073 Macrodomain Ter protein [matP]. 1 148 31.214 T 10-03-2017 IPR009390 Macrodomain Ter protein, MatP GO:0043565 RG49_RS00540 c6005499c71d5bf8abf7535f429b54e9 188 Gene3D G3DSA:3.10.180.10 1 187 1.2E-80 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS00540 c6005499c71d5bf8abf7535f429b54e9 188 SUPERFAMILY SSF54593 2 186 6.75E-71 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS00540 c6005499c71d5bf8abf7535f429b54e9 188 Pfam PF06185 YecM protein 10 185 2.6E-72 T 10-03-2017 IPR010393 Protein of unknown function DUF991 RG49_RS00130 3a124663d4fff86664f2714dfe6d4982 558 Pfam PF17151 Periplasmic sensor domain 35 220 5.8E-81 T 10-03-2017 IPR033416 Periplasmic sensor domain CHASE7 RG49_RS00130 3a124663d4fff86664f2714dfe6d4982 558 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 388 554 8.1E-63 T 10-03-2017 IPR000160 GGDEF domain RG49_RS00130 3a124663d4fff86664f2714dfe6d4982 558 SMART SM00267 381 555 3.8E-65 T 10-03-2017 IPR000160 GGDEF domain RG49_RS00130 3a124663d4fff86664f2714dfe6d4982 558 SUPERFAMILY SSF55073 397 556 3.92E-44 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS00130 3a124663d4fff86664f2714dfe6d4982 558 Gene3D G3DSA:3.30.70.270 394 556 2.1E-51 T 10-03-2017 RG49_RS00130 3a124663d4fff86664f2714dfe6d4982 558 Pfam PF00990 Diguanylate cyclase, GGDEF domain 392 551 3.0E-46 T 10-03-2017 IPR000160 GGDEF domain RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 6.4E-23 T 10-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 SMART SM00962 100 296 4.1E-120 T 10-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 Gene3D G3DSA:1.20.120.140 2 89 3.7E-36 T 10-03-2017 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 35.006 T 10-03-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 SMART SM00963 1 86 2.4E-37 T 10-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 Gene3D G3DSA:1.10.260.30 329 432 1.6E-41 T 10-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 Gene3D G3DSA:3.40.50.300 94 297 1.5E-79 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 Pfam PF02978 Signal peptide binding domain 329 427 2.1E-33 T 10-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 SUPERFAMILY SSF47446 329 431 3.6E-39 T 10-03-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 SMART SM00382 99 247 7.9E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 SUPERFAMILY SSF52540 42 354 1.21E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 1.1E-75 T 10-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 10-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS21980 dc53afad12a0f784058f00d211e93e90 453 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 4.2E-182 T 10-03-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 RG49_RS22920 221493648e7a2ad71b262251e251b3ee 453 Gene3D G3DSA:2.30.170.30 1 54 2.7E-26 T 10-03-2017 RG49_RS22920 221493648e7a2ad71b262251e251b3ee 453 Gene3D G3DSA:1.10.220.70 56 141 5.7E-35 T 10-03-2017 RG49_RS22920 221493648e7a2ad71b262251e251b3ee 453 PIRSF PIRSF018788 1 453 1.0E-232 T 10-03-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 RG49_RS22920 221493648e7a2ad71b262251e251b3ee 453 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 444 8.9E-203 T 10-03-2017 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 RG49_RS22920 221493648e7a2ad71b262251e251b3ee 453 Gene3D G3DSA:3.20.20.70 143 453 5.1E-158 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS16280 b5ba89c619a193c0f6e67f06b83eae54 283 Gene3D G3DSA:3.90.1480.10 23 267 2.6E-10 T 10-03-2017 RG49_RS16280 b5ba89c619a193c0f6e67f06b83eae54 283 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 1 259 1.0E-141 T 10-03-2017 RG49_RS16280 b5ba89c619a193c0f6e67f06b83eae54 283 TIGRFAM TIGR04437 WaaZ_KDO_III: 3-deoxy-D-manno-oct-2-ulosonate III transferase WaaZ 6 256 4.2E-145 T 10-03-2017 IPR031026 3-deoxy-D-manno-oct-2-ulosonate III transferase WaaZ RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SUPERFAMILY SSF46915 249 348 1.2E-25 T 10-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 PIRSF PIRSF005499 25 733 6.6E-302 T 10-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Gene3D G3DSA:1.10.10.400 249 336 1.2E-25 T 10-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Gene3D G3DSA:2.40.50.140 642 717 7.8E-28 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 26 716 30.622 T 10-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Pfam PF01138 3' exoribonuclease family, domain 1 39 167 9.6E-19 T 10-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Pfam PF01138 3' exoribonuclease family, domain 1 347 479 8.1E-21 T 10-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SUPERFAMILY SSF54791 577 645 1.37E-17 T 10-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SMART SM00316 643 713 4.5E-28 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Pfam PF03725 3' exoribonuclease family, domain 2 483 550 1.7E-4 T 10-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Pfam PF03725 3' exoribonuclease family, domain 2 170 233 4.8E-15 T 10-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Gene3D G3DSA:3.30.230.70 23 248 7.0E-85 T 10-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Gene3D G3DSA:3.30.230.70 337 565 5.6E-88 T 10-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 33 714 0.0 T 10-03-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Pfam PF00013 KH domain 580 637 4.8E-9 T 10-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SUPERFAMILY SSF50249 631 716 4.97E-23 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Gene3D G3DSA:3.30.1370.10 575 641 1.2E-26 T 10-03-2017 IPR004088 K Homology domain, type 1 GO:0003723 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 264 343 4.2E-26 T 10-03-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SMART SM00322 575 640 1.2E-12 T 10-03-2017 IPR004087 K Homology domain GO:0003676 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SUPERFAMILY SSF54211 21 167 1.06E-50 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SUPERFAMILY SSF54211 324 515 2.89E-46 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SUPERFAMILY SSF55666 473 571 1.82E-27 T 10-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 SUPERFAMILY SSF55666 168 258 2.24E-31 T 10-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS18825 101ce33da06207e5a3fa99c7d6762e1b 734 Pfam PF00575 S1 RNA binding domain 642 713 2.3E-23 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS19705 4534eacc6e3c9a9c98c9869e5c638fe6 318 Gene3D G3DSA:1.10.10.60 263 307 1.7E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS19705 4534eacc6e3c9a9c98c9869e5c638fe6 318 Pfam PF06719 AraC-type transcriptional regulator N-terminus 47 197 6.7E-38 T 10-03-2017 IPR009594 Transcription regulator HTH, AraC, N-terminal RG49_RS19705 4534eacc6e3c9a9c98c9869e5c638fe6 318 Gene3D G3DSA:1.10.10.60 207 262 1.4E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS19705 4534eacc6e3c9a9c98c9869e5c638fe6 318 SUPERFAMILY SSF46689 262 312 4.48E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS19705 4534eacc6e3c9a9c98c9869e5c638fe6 318 Pfam PF12833 Helix-turn-helix domain 232 307 1.8E-21 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS19705 4534eacc6e3c9a9c98c9869e5c638fe6 318 SMART SM00342 226 309 2.4E-30 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS19705 4534eacc6e3c9a9c98c9869e5c638fe6 318 SUPERFAMILY SSF46689 210 260 1.24E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02105 a07f7470e4a8752c31262d40de149de2 406 SUPERFAMILY SSF46785 12 77 1.18E-15 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02105 a07f7470e4a8752c31262d40de149de2 406 Gene3D G3DSA:1.10.10.10 12 80 6.8E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02105 a07f7470e4a8752c31262d40de149de2 406 SUPERFAMILY SSF53067 87 391 3.27E-45 T 10-03-2017 RG49_RS02105 a07f7470e4a8752c31262d40de149de2 406 Gene3D G3DSA:3.30.420.40 83 223 9.2E-33 T 10-03-2017 RG49_RS02105 a07f7470e4a8752c31262d40de149de2 406 Gene3D G3DSA:3.30.420.40 224 375 1.7E-43 T 10-03-2017 RG49_RS02105 a07f7470e4a8752c31262d40de149de2 406 Pfam PF00480 ROK family 90 389 4.3E-52 T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 816 894 8.2E-21 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Pfam PF07724 AAA domain (Cdc48 subfamily) 641 810 2.2E-52 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Gene3D G3DSA:1.10.8.60 450 533 4.1E-32 T 10-03-2017 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Gene3D G3DSA:3.40.50.300 596 825 1.2E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 SMART SM01086 816 907 2.9E-26 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Gene3D G3DSA:1.10.8.60 826 912 6.0E-24 T 10-03-2017 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 307 428 3.0E-15 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Gene3D G3DSA:3.40.50.300 263 448 3.8E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 SUPERFAMILY SSF81923 112 249 2.35E-24 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 SUPERFAMILY SSF52540 263 571 6.46E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 SUPERFAMILY SSF52540 591 886 2.37E-78 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 SMART SM00382 302 449 1.5E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 SMART SM00382 642 788 1.6E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.5E-41 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 691 709 1.5E-41 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 753 767 1.5E-41 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 720 738 1.5E-41 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Gene3D G3DSA:1.10.1780.10 111 248 3.2E-35 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 676 694 - T 10-03-2017 IPR028299 ClpA/B, conserved site 2 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 200 248 2.1E-15 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS10000 56abff39222ce66e1809a2c043ed7fd0 960 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 123 171 2.0E-8 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 126 134 - T 10-03-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 255 280 - T 10-03-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 Gene3D G3DSA:2.60.120.10 6 140 3.3E-66 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 Gene3D G3DSA:2.60.120.10 238 273 3.3E-66 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PIRSF PIRSF001480 1 391 2.5E-114 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 Gene3D G3DSA:2.60.120.10 288 376 1.5E-11 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 Pfam PF01238 Phosphomannose isomerase type I 1 357 3.5E-124 T 10-03-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 SUPERFAMILY SSF51182 1 375 1.65E-101 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 384 7.2E-147 T 10-03-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 220 235 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 255 274 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 274 293 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 PRINTS PR00714 Phosphomannose isomerase type I signature 236 255 4.3E-74 T 10-03-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 Gene3D G3DSA:1.10.441.10 274 287 2.2E-24 T 10-03-2017 RG49_RS01995 db79e4dbecd21e0c3a7736850a23e810 391 Gene3D G3DSA:1.10.441.10 141 231 2.2E-24 T 10-03-2017 RG49_RS11350 5403583dde618abfb0e97a384af9b5da 247 SUPERFAMILY SSF160950 4 247 7.72E-93 T 10-03-2017 RG49_RS11350 5403583dde618abfb0e97a384af9b5da 247 Pfam PF07072 Protein of unknown function (DUF1342) 19 225 1.5E-78 T 10-03-2017 IPR009777 Cell division protein ZapD RG49_RS11350 5403583dde618abfb0e97a384af9b5da 247 Hamap MF_01092 Cell division protein ZapD [zapD]. 4 247 32.966 T 10-03-2017 IPR009777 Cell division protein ZapD RG49_RS11350 5403583dde618abfb0e97a384af9b5da 247 Gene3D G3DSA:1.10.3900.10 13 173 2.2E-67 T 10-03-2017 RG49_RS11350 5403583dde618abfb0e97a384af9b5da 247 Gene3D G3DSA:2.60.440.10 174 247 5.7E-36 T 10-03-2017 IPR027462 Z ring-associated protein D, C-terminal domain RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 PRINTS PR00394 RHS protein signature 1215 1234 2.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 PRINTS PR00394 RHS protein signature 1137 1157 2.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 PRINTS PR00394 RHS protein signature 1168 1183 2.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 PRINTS PR00394 RHS protein signature 1192 1212 2.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 PRINTS PR00394 RHS protein signature 1099 1118 2.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF05593 RHS Repeat 637 674 2.6E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF05593 RHS Repeat 489 511 3.5E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF05593 RHS Repeat 361 391 2.3E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF05593 RHS Repeat 425 463 1.9E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF05593 RHS Repeat 535 568 4.7E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF05593 RHS Repeat 575 611 4.3E-9 T 10-03-2017 IPR031325 RHS repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF05593 RHS Repeat 939 984 3.8E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1170 1247 1.7E-22 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF14220 Domain of unknown function (DUF4329) 1280 1397 1.1E-32 T 10-03-2017 IPR025479 Domain of unknown function DUF4329 RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 473 508 5.0E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 678 7.8E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 596 627 4.8E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 451 482 0.0031 T 10-03-2017 IPR006530 YD repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 409 444 4.3E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 575 612 3.6E-9 T 10-03-2017 IPR006530 YD repeat RG49_RS17160 28cc364ab4d664dc4dbe30fb183fb7c9 1411 Pfam PF03527 RHS protein 1143 1180 2.0E-14 T 10-03-2017 IPR001826 RHS protein RG49_RS15700 344f447b7988c3072dc40e0fc1b81a54 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 18 105 3.0E-45 T 10-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 RG49_RS15700 344f447b7988c3072dc40e0fc1b81a54 119 Gene3D G3DSA:3.30.230.10 5 116 3.2E-34 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS15700 344f447b7988c3072dc40e0fc1b81a54 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 56 70 - T 10-03-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 RG49_RS15700 344f447b7988c3072dc40e0fc1b81a54 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 5 115 7.5E-38 T 10-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 RG49_RS15700 344f447b7988c3072dc40e0fc1b81a54 119 Pfam PF00825 Ribonuclease P 6 111 1.8E-32 T 10-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 RG49_RS15700 344f447b7988c3072dc40e0fc1b81a54 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 115 17.951 T 10-03-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 RG49_RS15700 344f447b7988c3072dc40e0fc1b81a54 119 SUPERFAMILY SSF54211 5 115 2.48E-31 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS07625 33955e2da127a0332391bab257013b0b 225 Gene3D G3DSA:3.40.50.2300 3 122 5.8E-37 T 10-03-2017 RG49_RS07625 33955e2da127a0332391bab257013b0b 225 SMART SM00448 2 112 2.4E-40 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS07625 33955e2da127a0332391bab257013b0b 225 Gene3D G3DSA:1.10.10.10 126 223 9.6E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07625 33955e2da127a0332391bab257013b0b 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 6.7E-22 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS07625 33955e2da127a0332391bab257013b0b 225 Pfam PF00072 Response regulator receiver domain 4 112 2.0E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS07625 33955e2da127a0332391bab257013b0b 225 SUPERFAMILY SSF52172 3 176 1.42E-39 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS07625 33955e2da127a0332391bab257013b0b 225 SMART SM00862 147 223 2.1E-22 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 SUPERFAMILY SSF53790 12 232 1.19E-84 T 10-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 213 2.2E-29 T 10-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 10-03-2017 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 Gene3D G3DSA:3.40.1010.10 12 120 8.1E-17 T 10-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 234 38.785 T 10-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 PIRSF PIRSF005917 1 286 1.4E-108 T 10-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 Gene3D G3DSA:3.30.950.10 121 236 4.6E-43 T 10-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS18925 455e664b1c8fe97fa200485a1d5a212b 286 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 283 4.4E-117 T 10-03-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS04920 c926b071be2bb64503954a817812997c 107 PIRSF PIRSF007036 1 107 2.0E-60 T 10-03-2017 IPR014448 Anti-adapter protein IraM GO:0005737|GO:0006950 RG49_RS04920 c926b071be2bb64503954a817812997c 107 Hamap MF_01199 Anti-adapter protein IraM [iraM]. 1 107 29.621 T 10-03-2017 IPR014448 Anti-adapter protein IraM GO:0005737|GO:0006950 RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 SUPERFAMILY SSF56784 1 250 6.73E-59 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 Gene3D G3DSA:3.40.50.1000 1 74 5.9E-42 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 Gene3D G3DSA:3.40.50.1000 179 251 5.9E-42 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 251 1.5E-54 T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 251 8.7E-52 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 Gene3D G3DSA:3.30.1240.10 84 178 1.1E-32 T 10-03-2017 RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 213 235 - T 10-03-2017 RG49_RS06785 d27ba6af7b040bc9873fe4a2ce007c69 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 232 3.6E-20 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 Gene3D G3DSA:1.10.240.10 238 321 2.7E-43 T 10-03-2017 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 SUPERFAMILY SSF52374 4 328 4.41E-111 T 10-03-2017 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 Gene3D G3DSA:3.40.50.620 4 237 3.2E-105 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 Pfam PF00579 tRNA synthetases class I (W and Y) 31 328 1.5E-94 T 10-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 4 423 46.949 T 10-03-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 Gene3D G3DSA:3.10.290.10 322 423 2.2E-30 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 SUPERFAMILY SSF55174 327 423 1.57E-20 T 10-03-2017 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 424 2.6E-152 T 10-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 Pfam PF01479 S4 domain 359 403 3.9E-6 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 SMART SM00363 358 419 3.5E-8 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 188 210 1.1E-32 T 10-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 1.1E-32 T 10-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 167 182 1.1E-32 T 10-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 RG49_RS01860 681af77515750a11db37bcd4ed5ebe76 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 221 233 1.1E-32 T 10-03-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 RG49_RS04415 5dfb8cec10b673adb722072f815ea2e4 205 Hamap MF_00124 Thymidine kinase [tdk]. 1 189 35.213 T 10-03-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 RG49_RS04415 5dfb8cec10b673adb722072f815ea2e4 205 SUPERFAMILY SSF52540 1 141 1.37E-39 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04415 5dfb8cec10b673adb722072f815ea2e4 205 PIRSF PIRSF035805 1 200 2.1E-57 T 10-03-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 RG49_RS04415 5dfb8cec10b673adb722072f815ea2e4 205 Gene3D G3DSA:3.30.60.20 142 190 3.3E-20 T 10-03-2017 RG49_RS04415 5dfb8cec10b673adb722072f815ea2e4 205 SUPERFAMILY SSF57716 142 189 1.39E-16 T 10-03-2017 RG49_RS04415 5dfb8cec10b673adb722072f815ea2e4 205 Pfam PF00265 Thymidine kinase 2 186 1.2E-67 T 10-03-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 RG49_RS04415 5dfb8cec10b673adb722072f815ea2e4 205 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 173 186 - T 10-03-2017 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 SUPERFAMILY SSF47413 1 85 4.05E-20 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 SUPERFAMILY SSF55234 88 155 2.09E-29 T 10-03-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 Gene3D G3DSA:1.10.260.40 1 86 8.7E-29 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 Pfam PF02560 Cyanate lyase C-terminal domain 87 154 3.9E-32 T 10-03-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 PRINTS PR01693 Cyanase signature 91 105 1.1E-35 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 PRINTS PR01693 Cyanase signature 109 125 1.1E-35 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 PRINTS PR01693 Cyanase signature 141 151 1.1E-35 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 PRINTS PR01693 Cyanase signature 42 59 1.1E-35 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 PRINTS PR01693 Cyanase signature 22 37 1.1E-35 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 SMART SM01116 83 156 6.1E-45 T 10-03-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 Gene3D G3DSA:3.30.1160.10 89 156 4.6E-36 T 10-03-2017 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 PIRSF PIRSF001263 3 156 4.2E-67 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 Hamap MF_00535 Cyanate hydratase [cynS]. 1 156 74.674 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS09435 1a86bc8e069e57eaa8c799523a09c105 156 TIGRFAM TIGR00673 cynS: cyanase 1 156 1.1E-73 T 10-03-2017 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS12470 85963507fe1013bc39ca9b5d64e5a5fd 368 Pfam PF01344 Kelch motif 75 122 7.4E-9 T 10-03-2017 IPR006652 Kelch repeat type 1 GO:0005515 RG49_RS12470 85963507fe1013bc39ca9b5d64e5a5fd 368 SUPERFAMILY SSF117281 191 356 1.16E-37 T 10-03-2017 RG49_RS12470 85963507fe1013bc39ca9b5d64e5a5fd 368 SUPERFAMILY SSF117281 40 156 1.16E-37 T 10-03-2017 RG49_RS12470 85963507fe1013bc39ca9b5d64e5a5fd 368 Gene3D G3DSA:2.120.10.80 191 363 1.3E-38 T 10-03-2017 IPR015915 Kelch-type beta propeller GO:0005515 RG49_RS12470 85963507fe1013bc39ca9b5d64e5a5fd 368 Gene3D G3DSA:2.120.10.80 39 159 1.3E-38 T 10-03-2017 IPR015915 Kelch-type beta propeller GO:0005515 RG49_RS12470 85963507fe1013bc39ca9b5d64e5a5fd 368 TIGRFAM TIGR03547 muta_rot_YjhT: mutatrotase, YjhT family 22 359 2.5E-144 T 10-03-2017 IPR019936 Mutatrotase, YjhT-like RG49_RS12470 85963507fe1013bc39ca9b5d64e5a5fd 368 Hamap MF_01195 N-acetylneuraminate epimerase [nanM]. 1 368 45.438 T 10-03-2017 IPR019936 Mutatrotase, YjhT-like RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 179 234 8.2E-23 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 SMART SM00421 177 234 1.1E-18 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 Pfam PF03472 Autoinducer binding domain 23 159 8.4E-33 T 10-03-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 Gene3D G3DSA:1.10.10.10 183 240 1.6E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 SUPERFAMILY SSF46894 162 240 5.1E-18 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 Gene3D G3DSA:3.30.450.80 7 182 1.6E-43 T 10-03-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 210 1.1E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 194 1.1E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 222 1.1E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 SUPERFAMILY SSF75516 8 170 9.02E-36 T 10-03-2017 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain RG49_RS00320 7c005e37f0070feafde13a57f729fae9 240 ProSitePatterns PS00622 LuxR-type HTH domain signature. 194 221 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS15985 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS02995 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS15605 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS16020 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS08415 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS19935 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS20780 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS09850 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS16555 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS03745 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS11135 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS09690 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS00080 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS09795 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS04870 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS03555 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS09580 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS19975 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS05530 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS16630 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS12510 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS09895 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS07860 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS03520 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS05015 7658312c5346998d7f996db05fc34bce 27 Pfam PF12759 InsA C-terminal domain 3 27 1.9E-15 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 SUPERFAMILY SSF50249 560 643 2.31E-19 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 SUPERFAMILY SSF50249 83 171 9.42E-32 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 6 643 4.9E-256 T 10-03-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 SUPERFAMILY SSF50249 8 80 1.17E-15 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 Hamap MF_01036 Exoribonuclease 2 [rnb]. 1 643 45.159 T 10-03-2017 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 SUPERFAMILY SSF50249 176 556 3.03E-116 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 Pfam PF08206 Ribonuclease B OB domain 24 80 2.4E-19 T 10-03-2017 IPR013223 Ribonuclease B, N-terminal OB domain RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 SMART SM00955 189 517 4.3E-129 T 10-03-2017 RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 SMART SM00357 23 79 1.7E-15 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 Pfam PF00575 S1 RNA binding domain 559 636 2.1E-11 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 Pfam PF00773 RNB domain 189 516 2.0E-84 T 10-03-2017 RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 TIGRFAM TIGR02062 RNase_B: exoribonuclease II 1 642 0.0 T 10-03-2017 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 RG49_RS04120 2d2602635040cf648349e31eaa98ca1d 644 ProSitePatterns PS01175 Ribonuclease II family signature. 484 508 - T 10-03-2017 IPR022966 Ribonuclease II/R, conserved site RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 PIRSF PIRSF001467 1 164 5.1E-29 T 10-03-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 1 162 3.4E-48 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 1.4E-11 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 1.4E-11 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 1.4E-11 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 Gene3D G3DSA:2.40.100.10 2 162 6.2E-56 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 10-03-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 RG49_RS08450 f49aebeb90a4ad3a326badae55e4200e 164 SUPERFAMILY SSF50891 1 162 5.7E-60 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 Pfam PF02803 Thiolase, C-terminal domain 270 392 1.7E-53 T 10-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 10-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 10-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 SUPERFAMILY SSF53901 4 270 5.43E-84 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 Gene3D G3DSA:3.40.47.10 144 194 5.2E-68 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 Gene3D G3DSA:3.40.47.10 277 392 5.2E-68 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 SUPERFAMILY SSF53901 271 392 8.74E-46 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 10-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 Pfam PF00108 Thiolase, N-terminal domain 4 263 8.1E-104 T 10-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 3.8E-149 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 Gene3D G3DSA:3.40.47.10 195 276 5.4E-75 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 Gene3D G3DSA:3.40.47.10 5 123 5.4E-75 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23990 15eb3880930988e5ef0c30f7e66d43b8 394 PIRSF PIRSF000429 1 394 6.3E-134 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS04585 0ee76a0fad6fa3a5e263937ab7232d9e 207 Pfam PF03550 Outer membrane lipoprotein LolB 50 204 9.3E-50 T 10-03-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 RG49_RS04585 0ee76a0fad6fa3a5e263937ab7232d9e 207 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 5 206 9.2E-100 T 10-03-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 RG49_RS04585 0ee76a0fad6fa3a5e263937ab7232d9e 207 SUPERFAMILY SSF89392 31 206 1.29E-56 T 10-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX RG49_RS04585 0ee76a0fad6fa3a5e263937ab7232d9e 207 Gene3D G3DSA:2.50.20.10 14 206 3.1E-71 T 10-03-2017 RG49_RS04585 0ee76a0fad6fa3a5e263937ab7232d9e 207 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 6 206 29.745 T 10-03-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 RG49_RS18600 58e1f9af0b98ce4caf583eb75bababe8 242 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 8 233 44.161 T 10-03-2017 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 RG49_RS18600 58e1f9af0b98ce4caf583eb75bababe8 242 Gene3D G3DSA:1.10.3810.10 62 231 6.2E-62 T 10-03-2017 RG49_RS18600 58e1f9af0b98ce4caf583eb75bababe8 242 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 13 231 2.3E-87 T 10-03-2017 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 RG49_RS18600 58e1f9af0b98ce4caf583eb75bababe8 242 Pfam PF00912 Transglycosylase 60 227 3.5E-52 T 10-03-2017 IPR001264 Glycosyl transferase, family 51 RG49_RS18600 58e1f9af0b98ce4caf583eb75bababe8 242 SUPERFAMILY SSF53955 51 231 9.0E-63 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 283 6.7E-38 T 10-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 SUPERFAMILY SSF51735 2 164 1.41E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 294 7.7E-157 T 10-03-2017 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 4.2E-51 T 10-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 10-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 PIRSF PIRSF000103 1 295 1.5E-96 T 10-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 SUPERFAMILY SSF48179 164 293 5.44E-37 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 Hamap MF_02032 2-hydroxy-3-oxopropionate reductase [garR]. 3 296 61.888 T 10-03-2017 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 Gene3D G3DSA:1.10.1040.10 166 294 1.3E-43 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS19045 5314430e8fff97a81c2d038c348ad1b4 296 Gene3D G3DSA:3.40.50.720 1 164 2.1E-62 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18375 b96efb474059a42b2d95c3386f11e1c2 162 Pfam PF04093 rod shape-determining protein MreD 5 155 1.7E-46 T 10-03-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 RG49_RS18375 b96efb474059a42b2d95c3386f11e1c2 162 PIRSF PIRSF018472 2 162 1.3E-57 T 10-03-2017 IPR026034 Cell shape-determining protein MreD, proteobacterial type RG49_RS18375 b96efb474059a42b2d95c3386f11e1c2 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 9 154 5.6E-42 T 10-03-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 Gene3D G3DSA:3.40.50.1000 90 185 1.6E-37 T 10-03-2017 IPR023214 HAD-like domain RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 Gene3D G3DSA:3.40.50.1000 4 18 1.6E-37 T 10-03-2017 IPR023214 HAD-like domain RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 5 185 4.4E-66 T 10-03-2017 IPR010976 Beta-phosphoglucomutase hydrolase RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 121 183 1.0E-15 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 Gene3D G3DSA:1.10.150.240 19 75 4.8E-4 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 183 3.7E-29 T 10-03-2017 IPR023214 HAD-like domain RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 SUPERFAMILY SSF56784 5 185 2.8E-46 T 10-03-2017 IPR023214 HAD-like domain RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 3.9E-7 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 3.9E-7 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 3.9E-7 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS21640 1a107e0316203262289f1c4569facdd5 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 3.9E-7 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS18410 e6807ec5cc83f681ac62c68c1bc8ef12 67 Hamap MF_01546 Protein AaeX [aaeX]. 1 67 24.567 T 10-03-2017 IPR012451 Protein of unknown function DUF1656 RG49_RS18410 e6807ec5cc83f681ac62c68c1bc8ef12 67 Pfam PF07869 Protein of unknown function (DUF1656) 7 61 3.5E-20 T 10-03-2017 IPR012451 Protein of unknown function DUF1656 RG49_RS17520 a92cc032b8a01cb91bacd45a79b194b6 78 Pfam PF09012 FeoC like transcriptional regulator 3 69 1.2E-15 T 10-03-2017 IPR015102 Transcriptional regulator HTH-type, FeoC RG49_RS17520 a92cc032b8a01cb91bacd45a79b194b6 78 Gene3D G3DSA:1.10.10.10 6 55 2.4E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17520 a92cc032b8a01cb91bacd45a79b194b6 78 SUPERFAMILY SSF46785 1 76 1.37E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17520 a92cc032b8a01cb91bacd45a79b194b6 78 Hamap MF_01586 Probable [Fe-S]-dependent transcriptional repressor [feoC]. 1 78 24.462 T 10-03-2017 IPR023732 Probable [Fe-S]-dependent transcriptional repressor RG49_RS11825 ded6960540ab6f6c00d19ca70b91570c 134 Pfam PF10807 Protein of unknown function (DUF2541) 3 132 1.2E-64 T 10-03-2017 IPR020240 Uncharacterised protein family UPF0412, YaaI RG49_RS11825 ded6960540ab6f6c00d19ca70b91570c 134 Hamap MF_01372 UPF0412 protein YaaI [yaaI]. 1 134 49.751 T 10-03-2017 IPR020240 Uncharacterised protein family UPF0412, YaaI RG49_RS11825 ded6960540ab6f6c00d19ca70b91570c 134 ProDom PD082838 YAAI PERIPLASMIC STY0011 ECS0013 PRECURSOR SIGNAL 16 134 4.0E-66 T 10-03-2017 IPR020240 Uncharacterised protein family UPF0412, YaaI RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 ProSitePatterns PS01335 Methylglyoxal synthase active site. 65 73 - T 10-03-2017 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 Pfam PF02142 MGS-like domain 26 118 2.7E-18 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 12 131 41.132 T 10-03-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 PIRSF PIRSF006614 8 151 5.2E-66 T 10-03-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 Gene3D G3DSA:3.40.50.1380 2 151 3.5E-66 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 SUPERFAMILY SSF52335 2 147 7.46E-59 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 11 151 1.8E-74 T 10-03-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 RG49_RS05900 0b784f1e718cda3780049f188bca61c1 152 SMART SM00851 25 118 6.7E-24 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 Hamap MF_01628 Thymidine phosphorylase [deoA]. 1 439 54.502 T 10-03-2017 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 5 423 4.0E-171 T 10-03-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 SUPERFAMILY SSF52418 74 334 1.05E-88 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 Gene3D G3DSA:3.90.1170.30 338 432 4.3E-37 T 10-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 67 9.8E-19 T 10-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 Pfam PF00591 Glycosyl transferase family, a/b domain 79 309 2.0E-53 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 PIRSF PIRSF000478 1 439 9.8E-155 T 10-03-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 SUPERFAMILY SSF47648 3 70 1.31E-21 T 10-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 113 128 - T 10-03-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase 2 438 8.8E-238 T 10-03-2017 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 Gene3D G3DSA:1.20.970.10 2 68 6.5E-30 T 10-03-2017 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 SMART SM00941 350 424 6.5E-30 T 10-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 350 423 1.3E-25 T 10-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 SUPERFAMILY SSF54680 337 438 4.58E-33 T 10-03-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS12005 94fbaf8d564a0b67e14ffce9ed0ee772 440 Gene3D G3DSA:3.40.1030.10 75 337 5.4E-111 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 Gene3D G3DSA:3.40.190.10 178 270 1.0E-30 T 10-03-2017 RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 5.7E-22 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 Pfam PF03466 LysR substrate binding domain 88 296 1.1E-45 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 Gene3D G3DSA:1.10.10.10 1 82 1.9E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 SUPERFAMILY SSF53850 89 296 2.05E-40 T 10-03-2017 RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 Gene3D G3DSA:3.40.190.10 90 177 9.5E-28 T 10-03-2017 RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 SUPERFAMILY SSF46785 4 89 5.7E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.3E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.3E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS02100 508c31c828d79d928641abcdb3141fb8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.3E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS05495 9ce746d7611832d309bb4dd16adfb71a 312 Gene3D G3DSA:3.40.50.720 94 278 6.9E-51 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05495 9ce746d7611832d309bb4dd16adfb71a 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 277 3.9E-45 T 10-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 RG49_RS05495 9ce746d7611832d309bb4dd16adfb71a 312 SUPERFAMILY SSF51735 99 278 3.28E-45 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05495 9ce746d7611832d309bb4dd16adfb71a 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216 232 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS05495 9ce746d7611832d309bb4dd16adfb71a 312 Hamap MF_01666 Glyoxylate/hydroxypyruvate reductase A [ghrA]. 1 312 64.702 T 10-03-2017 IPR023514 Glyoxylate/hydroxypyruvate reductase A GO:0016618|GO:0030267|GO:0055114 KEGG: 00260+1.1.1.81|KEGG: 00620+1.1.1.79|KEGG: 00630+1.1.1.79+1.1.1.81|MetaCyc: PWY-1622 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 Gene3D G3DSA:3.40.630.10 157 343 1.3E-79 T 10-03-2017 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 Gene3D G3DSA:3.40.630.10 3 70 1.3E-79 T 10-03-2017 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 Gene3D G3DSA:2.40.30.40 71 148 3.6E-26 T 10-03-2017 IPR023367 Peptidase M42, domain 2 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 PIRSF PIRSF001123 1 344 6.3E-119 T 10-03-2017 IPR008007 Peptidase M42 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 SUPERFAMILY SSF53187 3 77 6.04E-63 T 10-03-2017 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 SUPERFAMILY SSF53187 158 340 6.04E-63 T 10-03-2017 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 SUPERFAMILY SSF101821 67 166 1.53E-19 T 10-03-2017 RG49_RS23220 a57f618143db50ae3d71a0ddfd04480e 345 Pfam PF05343 M42 glutamyl aminopeptidase 43 325 3.7E-84 T 10-03-2017 IPR008007 Peptidase M42 RG49_RS18315 a787f761458c17db19fb243118344707 483 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 155 180 - T 10-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS18315 a787f761458c17db19fb243118344707 483 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 36 432 1.5E-115 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS18315 a787f761458c17db19fb243118344707 483 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 4 471 9.9E-229 T 10-03-2017 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0031402|GO:0071436 RG49_RS18315 a787f761458c17db19fb243118344707 483 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 414 434 - T 10-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS18315 a787f761458c17db19fb243118344707 483 Pfam PF00474 Sodium:solute symporter family 36 432 1.3E-142 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS07370 1ed5362504934d484cbe923df0583e6c 97 Pfam PF09600 Cyd operon protein YbgE (Cyd_oper_YbgE) 17 94 6.8E-34 T 10-03-2017 IPR011846 Cyd operon protein YbgE RG49_RS07370 1ed5362504934d484cbe923df0583e6c 97 TIGRFAM TIGR02112 cyd_oper_ybgE: cyd operon protein YbgE 5 97 2.0E-42 T 10-03-2017 IPR011846 Cyd operon protein YbgE RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 SUPERFAMILY SSF55681 243 525 1.27E-96 T 10-03-2017 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 SUPERFAMILY SSF81271 3 61 7.85E-17 T 10-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 631 1.2E-248 T 10-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 318 528 6.8E-52 T 10-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Pfam PF03129 Anticodon binding domain 541 630 4.6E-24 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Gene3D G3DSA:3.30.980.10 65 129 7.0E-42 T 10-03-2017 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Gene3D G3DSA:3.30.980.10 188 224 7.0E-42 T 10-03-2017 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 634 34.366 T 10-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 SMART SM00863 170 219 4.6E-19 T 10-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Pfam PF02824 TGS domain 4 61 9.6E-13 T 10-03-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 219 4.7E-14 T 10-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 1.4E-54 T 10-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 1.4E-54 T 10-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 1.4E-54 T 10-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 1.4E-54 T 10-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 1.4E-54 T 10-03-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Gene3D G3DSA:3.30.930.10 242 529 6.9E-122 T 10-03-2017 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 SUPERFAMILY SSF55186 63 241 1.83E-65 T 10-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Gene3D G3DSA:3.10.20.30 1 64 1.6E-24 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Gene3D G3DSA:3.40.50.800 532 640 6.5E-40 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 Gene3D G3DSA:3.30.54.20 130 187 5.6E-20 T 10-03-2017 RG49_RS01420 94d890c8500b73dc09b67543b299a8ec 642 SUPERFAMILY SSF52954 530 636 2.11E-34 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 Pfam PF01565 FAD binding domain 52 192 1.1E-37 T 10-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 Pfam PF02913 FAD linked oxidases, C-terminal domain 281 539 2.0E-65 T 10-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 SUPERFAMILY SSF46548 655 691 2.35E-8 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 SUPERFAMILY SSF46548 518 622 2.35E-8 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 Gene3D G3DSA:1.10.1060.10 516 619 1.1E-15 T 10-03-2017 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 Gene3D G3DSA:1.10.1060.10 654 706 1.1E-15 T 10-03-2017 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 SUPERFAMILY SSF55103 257 542 1.8E-52 T 10-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 673 684 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 Gene3D G3DSA:3.30.465.10 110 282 1.1E-42 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 Pfam PF13183 4Fe-4S dicluster domain 576 687 1.5E-12 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 Gene3D G3DSA:3.30.43.10 2 109 2.3E-31 T 10-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 RG49_RS01600 1db2da07f2c6679f69747b087c839f07 1018 SUPERFAMILY SSF56176 18 282 4.21E-55 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS23070 909981ff266ee1accd4aa9206a0e7129 328 Hamap MF_00509 Cell division protein ZipA [zipA]. 3 322 24.652 T 10-03-2017 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 RG49_RS23070 909981ff266ee1accd4aa9206a0e7129 328 SUPERFAMILY SSF64383 192 325 3.79E-48 T 10-03-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 RG49_RS23070 909981ff266ee1accd4aa9206a0e7129 328 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 194 317 2.6E-47 T 10-03-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 RG49_RS23070 909981ff266ee1accd4aa9206a0e7129 328 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 4 320 4.0E-126 T 10-03-2017 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 RG49_RS23070 909981ff266ee1accd4aa9206a0e7129 328 SMART SM00771 191 320 5.6E-75 T 10-03-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 RG49_RS23070 909981ff266ee1accd4aa9206a0e7129 328 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 193 328 1.0E-75 T 10-03-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 RG49_RS23070 909981ff266ee1accd4aa9206a0e7129 328 Gene3D G3DSA:3.30.1400.10 190 325 4.1E-62 T 10-03-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 SUPERFAMILY SSF54373 269 359 7.85E-17 T 10-03-2017 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 SUPERFAMILY SSF51905 107 271 2.07E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 SUPERFAMILY SSF51905 1 54 2.07E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 SUPERFAMILY SSF51905 359 417 2.07E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 Gene3D G3DSA:3.30.9.10 270 352 8.1E-15 T 10-03-2017 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 Gene3D G3DSA:3.30.9.10 135 193 8.1E-15 T 10-03-2017 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 Gene3D G3DSA:3.40.50.720 194 269 5.9E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 Gene3D G3DSA:3.40.50.720 1 96 5.9E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 Gene3D G3DSA:3.40.50.720 353 415 5.9E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 410 55.739 T 10-03-2017 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 RG49_RS04715 520656e2a724f46b72d4c4e377c0a1d1 432 Pfam PF01266 FAD dependent oxidoreductase 2 397 2.0E-69 T 10-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 RG49_RS05490 bd3073b09524393ed6f41fb22eabd1e8 245 SMART SM00481 4 78 6.3E-21 T 10-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 RG49_RS05490 bd3073b09524393ed6f41fb22eabd1e8 245 Pfam PF02811 PHP domain 5 80 1.9E-8 T 10-03-2017 IPR004013 PHP domain GO:0003824 RG49_RS05490 bd3073b09524393ed6f41fb22eabd1e8 245 SUPERFAMILY SSF89550 3 241 4.05E-64 T 10-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 RG49_RS05490 bd3073b09524393ed6f41fb22eabd1e8 245 Gene3D G3DSA:3.20.20.140 1 237 1.8E-64 T 10-03-2017 RG49_RS05490 bd3073b09524393ed6f41fb22eabd1e8 245 Hamap MF_01561 Probable phosphatase YcdX [ycdX]. 1 243 52.299 T 10-03-2017 IPR023710 Probable phosphatase YcdX GO:0008270 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 SUPERFAMILY SSF53155 187 267 7.06E-21 T 10-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 SUPERFAMILY SSF46767 268 348 1.29E-30 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 SMART SM00342 99 181 8.9E-22 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Gene3D G3DSA:3.30.160.70 175 267 5.0E-34 T 10-03-2017 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Gene3D G3DSA:1.10.10.10 268 349 5.4E-34 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Gene3D G3DSA:3.40.10.10 3 86 2.2E-36 T 10-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 189 266 1.4E-21 T 10-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 PIRSF PIRSF000409 1 354 4.3E-146 T 10-03-2017 IPR016221 Bifunctional regulatory protein Ada RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 SUPERFAMILY SSF57884 2 92 2.62E-34 T 10-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 86 128 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 319 325 - T 10-03-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 270 348 4.2E-32 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 SUPERFAMILY SSF46689 85 133 1.34E-9 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Pfam PF12833 Helix-turn-helix domain 105 181 9.8E-16 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Pfam PF02805 Metal binding domain of Ada 11 75 3.9E-32 T 10-03-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 269 348 1.2E-37 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 Gene3D G3DSA:1.10.10.60 87 139 4.0E-25 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS24060 9de1304dddfe6ef9d0257c6719489cff 354 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 177 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS07910 5b1d4e45bb80d6e0c2b893a43498207d 213 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 3 213 30.093 T 10-03-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 RG49_RS07910 5b1d4e45bb80d6e0c2b893a43498207d 213 SUPERFAMILY SSF52374 3 213 1.91E-59 T 10-03-2017 RG49_RS07910 5b1d4e45bb80d6e0c2b893a43498207d 213 Gene3D G3DSA:3.40.50.620 6 213 9.1E-67 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07910 5b1d4e45bb80d6e0c2b893a43498207d 213 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 68 7.3E-13 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS07910 5b1d4e45bb80d6e0c2b893a43498207d 213 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 7 212 2.2E-63 T 10-03-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 RG49_RS07910 5b1d4e45bb80d6e0c2b893a43498207d 213 Pfam PF01467 Cytidylyltransferase-like 7 187 2.0E-37 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS16535 04ef2733d4ed39485e4538cb90df4e68 378 Pfam PF00529 HlyD membrane-fusion protein of T1SS 11 367 1.4E-13 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS16535 04ef2733d4ed39485e4538cb90df4e68 378 SUPERFAMILY SSF111369 167 301 1.31E-5 T 10-03-2017 RG49_RS16535 04ef2733d4ed39485e4538cb90df4e68 378 Gene3D G3DSA:2.40.50.100 65 96 1.3E-12 T 10-03-2017 RG49_RS16535 04ef2733d4ed39485e4538cb90df4e68 378 Gene3D G3DSA:2.40.50.100 219 242 1.3E-12 T 10-03-2017 RG49_RS16535 04ef2733d4ed39485e4538cb90df4e68 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 163 301 1.5E-9 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS16535 04ef2733d4ed39485e4538cb90df4e68 378 SUPERFAMILY SSF111369 60 139 2.88E-10 T 10-03-2017 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 31 177 6.0E-55 T 10-03-2017 IPR019247 Histidine kinase BarA, N-terminal RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SUPERFAMILY SSF47226 764 777 7.33E-22 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SUPERFAMILY SSF47226 808 909 7.33E-22 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Gene3D G3DSA:1.10.287.130 284 342 6.5E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 9.9E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 9.9E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 9.9E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 9.9E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Pfam PF00512 His Kinase A (phospho-acceptor) domain 293 357 2.2E-20 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SUPERFAMILY SSF47384 277 358 1.96E-22 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SUPERFAMILY SSF52172 668 785 3.7E-35 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SMART SM00387 404 520 2.3E-37 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SUPERFAMILY SSF158472 200 249 7.45E-5 T 10-03-2017 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Pfam PF01627 Hpt domain 828 908 1.3E-12 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Gene3D G3DSA:3.30.565.10 343 518 2.1E-44 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 404 519 3.0E-30 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SMART SM00073 819 914 1.6E-23 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Gene3D G3DSA:1.20.120.160 820 916 1.7E-20 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Gene3D G3DSA:3.40.50.2300 668 783 5.5E-37 T 10-03-2017 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SUPERFAMILY SSF55874 346 516 8.38E-44 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SMART SM00388 292 357 1.2E-25 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Pfam PF00072 Response regulator receiver domain 670 780 3.4E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 Pfam PF00672 HAMP domain 181 248 1.4E-11 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SMART SM00304 200 252 1.7E-7 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS21120 72978632c51f18b6449e7f060a82d213 918 SMART SM00448 668 781 4.9E-33 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS23105 d273c6e2ab3e7543c571307a7fbfc102 418 Gene3D G3DSA:1.20.1250.20 206 409 3.6E-22 T 10-03-2017 RG49_RS23105 d273c6e2ab3e7543c571307a7fbfc102 418 Gene3D G3DSA:1.20.1250.20 8 187 7.3E-12 T 10-03-2017 RG49_RS23105 d273c6e2ab3e7543c571307a7fbfc102 418 SUPERFAMILY SSF103473 7 408 3.01E-34 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23105 d273c6e2ab3e7543c571307a7fbfc102 418 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 418 9.9E-228 T 10-03-2017 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 RG49_RS23105 d273c6e2ab3e7543c571307a7fbfc102 418 Pfam PF03825 Nucleoside H+ symporter 1 407 4.9E-190 T 10-03-2017 RG49_RS01110 37bbc67667f5d7a6c941d5eeaf24116e 459 SUPERFAMILY SSF103473 14 449 1.57E-63 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01110 37bbc67667f5d7a6c941d5eeaf24116e 459 Gene3D G3DSA:1.20.1250.20 25 218 1.0E-25 T 10-03-2017 RG49_RS01110 37bbc67667f5d7a6c941d5eeaf24116e 459 Pfam PF00083 Sugar (and other) transporter 57 451 1.1E-32 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS01110 37bbc67667f5d7a6c941d5eeaf24116e 459 Gene3D G3DSA:1.20.1250.20 264 443 3.3E-18 T 10-03-2017 RG49_RS03135 61f21437f19127123be30db1665f4f22 700 Pfam PF00593 TonB dependent receptor 448 695 3.0E-36 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS03135 61f21437f19127123be30db1665f4f22 700 Gene3D G3DSA:2.170.130.10 28 151 6.6E-27 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS03135 61f21437f19127123be30db1665f4f22 700 Gene3D G3DSA:2.40.170.20 152 695 3.0E-108 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS03135 61f21437f19127123be30db1665f4f22 700 Pfam PF07715 TonB-dependent Receptor Plug Domain 40 151 6.8E-22 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS03135 61f21437f19127123be30db1665f4f22 700 SUPERFAMILY SSF56935 25 696 3.43E-120 T 10-03-2017 RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 SUPERFAMILY SSF51161 5 260 2.63E-68 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 193 226 6.0E-10 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 Gene3D G3DSA:2.160.10.10 143 252 1.3E-31 T 10-03-2017 RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 Gene3D G3DSA:1.10.3130.10 7 142 1.3E-52 T 10-03-2017 RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 SMART SM00971 9 113 3.2E-65 T 10-03-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 82 242 2.5E-75 T 10-03-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 RG49_RS16370 dbf5255db46feff6ef72b63754671791 273 Pfam PF06426 Serine acetyltransferase, N-terminal 9 113 9.1E-40 T 10-03-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 RG49_RS00895 a26f4541e13f5f48b320c36752d290b1 518 Pfam PF03741 Integral membrane protein TerC family 14 203 8.9E-49 T 10-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 RG49_RS00895 a26f4541e13f5f48b320c36752d290b1 518 Gene3D G3DSA:3.30.465.10 427 517 8.6E-21 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS00895 a26f4541e13f5f48b320c36752d290b1 518 SUPERFAMILY SSF54631 288 422 3.41E-22 T 10-03-2017 RG49_RS00895 a26f4541e13f5f48b320c36752d290b1 518 Gene3D G3DSA:3.10.580.10 286 426 1.0E-11 T 10-03-2017 RG49_RS00895 a26f4541e13f5f48b320c36752d290b1 518 Pfam PF03471 Transporter associated domain 434 509 2.6E-17 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS00895 a26f4541e13f5f48b320c36752d290b1 518 SMART SM01091 431 511 3.5E-21 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS00895 a26f4541e13f5f48b320c36752d290b1 518 SUPERFAMILY SSF56176 432 517 3.82E-18 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS09940 b9115a55d075794b1e3f6f74cbbea5ae 269 Gene3D G3DSA:3.90.850.10 2 259 2.3E-92 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS09940 b9115a55d075794b1e3f6f74cbbea5ae 269 SUPERFAMILY SSF56529 1 259 2.62E-79 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS09940 b9115a55d075794b1e3f6f74cbbea5ae 269 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 81 259 4.8E-21 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS09940 b9115a55d075794b1e3f6f74cbbea5ae 269 Hamap MF_01655 2-keto-4-pentenoate hydratase [mhpD]. 1 260 56.319 T 10-03-2017 IPR023793 2-keto-4-pentenoate hydratase GO:0008684|GO:0019439|GO:0030145 KEGG: 00360+4.2.1.80|KEGG: 00362+4.2.1.80|KEGG: 00621+4.2.1.80|KEGG: 00622+4.2.1.80|MetaCyc: PWY-5162 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Gene3D G3DSA:3.20.20.60 363 679 5.1E-106 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Gene3D G3DSA:1.10.274.10 149 238 1.1E-19 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Pfam PF05524 PEP-utilising enzyme, N-terminal 119 234 3.9E-13 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 360 650 8.0E-107 T 10-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 RG49_RS23225 7417078e73a719b801f800934f78a215 831 SUPERFAMILY SSF55804 685 826 1.83E-30 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Pfam PF00381 PTS HPr component phosphorylation site 8 83 9.8E-12 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23225 7417078e73a719b801f800934f78a215 831 Gene3D G3DSA:3.50.30.10 239 362 1.2E-24 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Gene3D G3DSA:3.40.930.10 682 827 3.3E-41 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS23225 7417078e73a719b801f800934f78a215 831 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 118 674 3.7E-152 T 10-03-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 RG49_RS23225 7417078e73a719b801f800934f78a215 831 SUPERFAMILY SSF52009 233 349 4.58E-20 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS23225 7417078e73a719b801f800934f78a215 831 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 573 588 1.2E-23 T 10-03-2017 RG49_RS23225 7417078e73a719b801f800934f78a215 831 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 609 621 1.2E-23 T 10-03-2017 RG49_RS23225 7417078e73a719b801f800934f78a215 831 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 402 421 1.2E-23 T 10-03-2017 RG49_RS23225 7417078e73a719b801f800934f78a215 831 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 556 571 1.2E-23 T 10-03-2017 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Pfam PF00391 PEP-utilising enzyme, mobile domain 262 334 4.8E-14 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS23225 7417078e73a719b801f800934f78a215 831 SUPERFAMILY SSF51621 359 658 1.62E-101 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Gene3D G3DSA:3.30.1340.10 1 87 7.4E-21 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23225 7417078e73a719b801f800934f78a215 831 SUPERFAMILY SSF55594 1 86 2.36E-16 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23225 7417078e73a719b801f800934f78a215 831 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 687 812 1.1E-40 T 10-03-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 RG49_RS23225 7417078e73a719b801f800934f78a215 831 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 687 826 7.6E-32 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS23225 7417078e73a719b801f800934f78a215 831 SUPERFAMILY SSF47831 148 247 3.79E-17 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS23225 7417078e73a719b801f800934f78a215 831 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 556 574 - T 10-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 PIRSF PIRSF000549 1 644 3.1E-293 T 10-03-2017 IPR016230 Serine-protein kinase, PrkA GO:0004672 RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 Pfam PF08298 PrkA AAA domain 20 380 2.1E-180 T 10-03-2017 IPR013153 PrkA AAA domain RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 Pfam PF06798 PrkA serine protein kinase C-terminal domain 383 636 1.7E-76 T 10-03-2017 IPR010650 PrkA C-terminal domain RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 SUPERFAMILY SSF52540 241 368 3.57E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 SUPERFAMILY SSF52540 75 154 3.57E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 Gene3D G3DSA:3.40.50.300 75 158 2.0E-8 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 Gene3D G3DSA:3.40.50.300 243 329 2.0E-8 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01070 7d791ccfa3356359facd9673f209c23a 644 SMART SM00763 19 380 1.2E-217 T 10-03-2017 IPR013153 PrkA AAA domain RG49_RS13190 8a819b1319a310a32369306016a392b8 188 Gene3D G3DSA:2.40.50.140 66 129 4.5E-26 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13190 8a819b1319a310a32369306016a392b8 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 72 123 9.7E-23 T 10-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 RG49_RS13190 8a819b1319a310a32369306016a392b8 188 SUPERFAMILY SSF50249 70 128 2.31E-18 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13190 8a819b1319a310a32369306016a392b8 188 PIRSF PIRSF005901 2 188 9.6E-67 T 10-03-2017 IPR020599 Translation elongation factor P/YeiP RG49_RS13190 8a819b1319a310a32369306016a392b8 188 SUPERFAMILY SSF50249 130 187 1.2E-18 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13190 8a819b1319a310a32369306016a392b8 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 10-03-2017 IPR013852 Translation elongation factor P/YeiP, conserved site RG49_RS13190 8a819b1319a310a32369306016a392b8 188 Gene3D G3DSA:2.30.30.30 2 64 6.2E-26 T 10-03-2017 IPR014722 Ribosomal protein L2 domain 2 RG49_RS13190 8a819b1319a310a32369306016a392b8 188 TIGRFAM TIGR00038 efp: translation elongation factor P 6 187 2.5E-76 T 10-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 RG49_RS13190 8a819b1319a310a32369306016a392b8 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 4.2E-26 T 10-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 RG49_RS13190 8a819b1319a310a32369306016a392b8 188 SUPERFAMILY SSF50104 3 63 2.35E-17 T 10-03-2017 IPR008991 Translation protein SH3-like domain RG49_RS13190 8a819b1319a310a32369306016a392b8 188 Gene3D G3DSA:2.40.50.140 130 187 3.6E-29 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13190 8a819b1319a310a32369306016a392b8 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 7 61 1.6E-23 T 10-03-2017 IPR013185 Translation elongation factor, KOW-like RG49_RS13190 8a819b1319a310a32369306016a392b8 188 SMART SM00841 131 186 6.9E-33 T 10-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 RG49_RS13190 8a819b1319a310a32369306016a392b8 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 50.871 T 10-03-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 RG49_RS13190 8a819b1319a310a32369306016a392b8 188 SMART SM01185 69 123 1.6E-26 T 10-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 SUPERFAMILY SSF55031 181 295 4.19E-21 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 Pfam PF07687 Peptidase dimerisation domain 178 288 2.4E-25 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 10 377 5.9E-175 T 10-03-2017 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 Gene3D G3DSA:3.40.630.10 5 189 5.0E-64 T 10-03-2017 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 Gene3D G3DSA:3.40.630.10 323 381 5.0E-64 T 10-03-2017 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 SUPERFAMILY SSF53187 305 381 6.56E-60 T 10-03-2017 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 SUPERFAMILY SSF53187 5 180 6.56E-60 T 10-03-2017 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 Gene3D G3DSA:3.30.70.360 190 290 2.4E-26 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 Pfam PF01546 Peptidase family M20/M25/M40 76 377 2.0E-33 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 Hamap MF_01108 Acetylornithine deacetylase [argE]. 3 382 68.146 T 10-03-2017 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 10-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 RG49_RS14325 92a37e9240f942f7c12447ad1e114e82 383 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 110 147 - T 10-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 RG49_RS06880 8bf60ff4a252319a1b889b66e4ab2040 220 Pfam PF00923 Transaldolase 3 205 3.8E-44 T 10-03-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS06880 8bf60ff4a252319a1b889b66e4ab2040 220 ProSitePatterns PS00958 Transaldolase active site. 82 99 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS06880 8bf60ff4a252319a1b889b66e4ab2040 220 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS06880 8bf60ff4a252319a1b889b66e4ab2040 220 Hamap MF_00496 Fructose-6-phosphate aldolase [fsa]. 1 220 51.18 T 10-03-2017 IPR023001 Fructose-6-phosphate aldolase GO:0016832 RG49_RS06880 8bf60ff4a252319a1b889b66e4ab2040 220 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 214 5.2E-84 T 10-03-2017 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS06880 8bf60ff4a252319a1b889b66e4ab2040 220 SUPERFAMILY SSF51569 1 216 5.4E-62 T 10-03-2017 RG49_RS06880 8bf60ff4a252319a1b889b66e4ab2040 220 Gene3D G3DSA:3.20.20.70 1 213 5.2E-60 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 553 805 1.1E-102 T 10-03-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 31 276 1.3E-99 T 10-03-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 SUPERFAMILY SSF81301 9 286 7.85E-92 T 10-03-2017 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 SUPERFAMILY SSF81593 818 943 1.96E-33 T 10-03-2017 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 27 945 20.185 T 10-03-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 Gene3D G3DSA:3.30.460.10 639 811 9.4E-63 T 10-03-2017 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 Gene3D G3DSA:3.30.460.10 113 285 4.6E-62 T 10-03-2017 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 SUPERFAMILY SSF81301 525 815 2.22E-89 T 10-03-2017 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 Pfam PF08335 GlnD PII-uridylyltransferase 825 916 4.2E-12 T 10-03-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 Pfam PF08335 GlnD PII-uridylyltransferase 297 436 9.9E-47 T 10-03-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 RG49_RS19480 0476e1bcd0784659ebabe04cc3102575 946 SUPERFAMILY SSF81593 287 436 5.65E-47 T 10-03-2017 RG49_RS14650 57a2292d55fc3b2bb2b01c9726349348 104 Hamap MF_01663 L-rhamnose mutarotase [rhaM]. 1 104 32.86 T 10-03-2017 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 RG49_RS14650 57a2292d55fc3b2bb2b01c9726349348 104 TIGRFAM TIGR02625 YiiL_rotase: L-rhamnose mutarotase 3 103 1.5E-58 T 10-03-2017 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 RG49_RS14650 57a2292d55fc3b2bb2b01c9726349348 104 SUPERFAMILY SSF54909 1 104 3.61E-38 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS14650 57a2292d55fc3b2bb2b01c9726349348 104 Pfam PF05336 Domain of unknown function (DUF718) 3 103 8.8E-30 T 10-03-2017 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Gene3D G3DSA:3.30.56.20 402 475 2.2E-29 T 10-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SMART SM00873 212 385 2.7E-101 T 10-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Gene3D G3DSA:3.30.70.380 703 794 1.8E-31 T 10-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 794 3.4E-304 T 10-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SUPERFAMILY SSF55681 467 690 2.53E-55 T 10-03-2017 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Gene3D G3DSA:3.30.56.10 155 183 6.9E-29 T 10-03-2017 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Gene3D G3DSA:3.30.56.10 1 38 6.9E-29 T 10-03-2017 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Gene3D G3DSA:3.30.930.10 496 690 5.8E-66 T 10-03-2017 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Pfam PF03147 Ferredoxin-fold anticodon binding domain 701 794 1.4E-28 T 10-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Gene3D G3DSA:3.50.40.10 198 392 9.0E-88 T 10-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Gene3D G3DSA:2.40.50.140 42 154 2.8E-46 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SMART SM00896 701 794 9.7E-46 T 10-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Pfam PF03484 tRNA synthetase B5 domain 405 471 8.0E-21 T 10-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Pfam PF01588 Putative tRNA binding domain 45 145 1.0E-27 T 10-03-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SUPERFAMILY SSF56037 197 393 1.36E-78 T 10-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SMART SM00874 403 471 1.2E-31 T 10-03-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Pfam PF03483 B3/4 domain 212 385 5.0E-72 T 10-03-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SUPERFAMILY SSF54991 696 794 5.23E-31 T 10-03-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 788 50.332 T 10-03-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SUPERFAMILY SSF46955 403 475 2.93E-21 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS01455 8ce280e365c9c63405943ffe355b2d58 795 SUPERFAMILY SSF50249 35 197 4.9E-52 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 SUPERFAMILY SSF56059 83 347 1.18E-68 T 10-03-2017 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 Gene3D G3DSA:3.30.470.20 204 444 2.8E-100 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 447 4.1E-252 T 10-03-2017 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 SUPERFAMILY SSF52440 1 113 1.22E-46 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 SUPERFAMILY SSF51246 331 444 6.28E-44 T 10-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.1E-44 T 10-03-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 6.6E-38 T 10-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 SMART SM00878 336 441 4.2E-65 T 10-03-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 2.1E-86 T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 Gene3D G3DSA:3.30.1490.20 130 203 7.8E-30 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 Gene3D G3DSA:3.40.50.20 1 129 9.4E-51 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS18325 41dd90eee557d2a8128cce90ddaca9a8 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS04600 2e7cf83cf1e1cc32b498008d23b31f65 559 ProSitePatterns PS01130 SLC26A transporters signature. 58 79 - T 10-03-2017 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 RG49_RS04600 2e7cf83cf1e1cc32b498008d23b31f65 559 Pfam PF01740 STAS domain 453 553 6.8E-12 T 10-03-2017 IPR002645 STAS domain RG49_RS04600 2e7cf83cf1e1cc32b498008d23b31f65 559 Gene3D G3DSA:3.30.750.24 453 557 1.2E-12 T 10-03-2017 IPR002645 STAS domain RG49_RS04600 2e7cf83cf1e1cc32b498008d23b31f65 559 Pfam PF00916 Sulfate permease family 29 411 1.6E-75 T 10-03-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 RG49_RS04600 2e7cf83cf1e1cc32b498008d23b31f65 559 SUPERFAMILY SSF52091 452 557 8.04E-15 T 10-03-2017 IPR002645 STAS domain RG49_RS04600 2e7cf83cf1e1cc32b498008d23b31f65 559 TIGRFAM TIGR00815 sulP: sulfate permease 18 555 1.2E-150 T 10-03-2017 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 RG49_RS16265 af9a3a3b8c616d6e1929a36575937325 339 Pfam PF08437 Glycosyl transferase family 8 C-terminal 280 336 5.2E-22 T 10-03-2017 IPR013645 Glycosyl transferase, family 8, C-terminal GO:0008918|GO:0009103 RG49_RS16265 af9a3a3b8c616d6e1929a36575937325 339 Gene3D G3DSA:3.90.550.10 30 301 8.9E-60 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS16265 af9a3a3b8c616d6e1929a36575937325 339 Pfam PF01501 Glycosyl transferase family 8 31 277 1.3E-66 T 10-03-2017 IPR002495 Glycosyl transferase, family 8 GO:0016757 RG49_RS16265 af9a3a3b8c616d6e1929a36575937325 339 SUPERFAMILY SSF53448 30 300 5.62E-60 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Pfam PF03144 Elongation factor Tu domain 2 219 289 9.5E-10 T 10-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 PRINTS PR00315 GTP-binding elongation factor signature 87 98 9.6E-15 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 PRINTS PR00315 GTP-binding elongation factor signature 123 132 9.6E-15 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 PRINTS PR00315 GTP-binding elongation factor signature 71 81 9.6E-15 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 PRINTS PR00315 GTP-binding elongation factor signature 51 59 9.6E-15 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 PRINTS PR00315 GTP-binding elongation factor signature 7 20 9.6E-15 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS14820 82f33c2557715805d8af5a024061e004 607 SUPERFAMILY SSF54980 302 387 1.69E-15 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Gene3D G3DSA:3.30.70.240 400 478 3.0E-31 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS14820 82f33c2557715805d8af5a024061e004 607 SUPERFAMILY SSF52540 3 219 1.38E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14820 82f33c2557715805d8af5a024061e004 607 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 8.7E-294 T 10-03-2017 IPR006298 GTP-binding protein TypA GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 SUPERFAMILY SSF54980 398 512 2.16E-26 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Gene3D G3DSA:3.40.50.300 3 205 1.9E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Gene3D G3DSA:2.40.30.10 206 303 2.1E-26 T 10-03-2017 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Pfam PF00679 Elongation factor G C-terminus 397 477 4.5E-22 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS14820 82f33c2557715805d8af5a024061e004 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 134 2.2E-25 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 SUPERFAMILY SSF50447 151 299 4.64E-34 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Pfam PF00009 Elongation factor Tu GTP binding domain 4 195 7.5E-58 T 10-03-2017 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Gene3D G3DSA:2.40.50.250 483 577 1.9E-40 T 10-03-2017 RG49_RS14820 82f33c2557715805d8af5a024061e004 607 Gene3D G3DSA:3.30.70.870 304 399 7.9E-38 T 10-03-2017 RG49_RS03920 01b386065c3f2d61e5463a7369bbc6c7 168 Pfam PF08534 Redoxin 20 163 3.9E-31 T 10-03-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 RG49_RS03920 01b386065c3f2d61e5463a7369bbc6c7 168 ProSitePatterns PS01265 Tpx family signature. 84 95 - T 10-03-2017 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 RG49_RS03920 01b386065c3f2d61e5463a7369bbc6c7 168 Gene3D G3DSA:3.40.30.10 4 168 8.2E-47 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS03920 01b386065c3f2d61e5463a7369bbc6c7 168 SUPERFAMILY SSF52833 4 164 3.34E-45 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS03920 01b386065c3f2d61e5463a7369bbc6c7 168 Hamap MF_00269 Probable thiol peroxidase [tpx]. 4 167 39.965 T 10-03-2017 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.313 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.3E-18 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.3E-18 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.3E-18 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.3E-18 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 8.1E-38 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 Pfam PF01084 Ribosomal protein S18 19 68 7.8E-25 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 71 3.0E-22 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 SUPERFAMILY SSF46911 3 74 7.06E-29 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 10-03-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12895 4d776f2becc435db4210658806b3f9df 75 Gene3D G3DSA:4.10.640.10 8 74 1.1E-32 T 10-03-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS13115 bc1377fbeb5bc6d135408d113bef1cdf 322 Pfam PF02666 Phosphatidylserine decarboxylase 63 282 1.5E-59 T 10-03-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 RG49_RS13115 bc1377fbeb5bc6d135408d113bef1cdf 322 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 49 286 6.1E-103 T 10-03-2017 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 RG49_RS13115 bc1377fbeb5bc6d135408d113bef1cdf 322 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 287 51.248 T 10-03-2017 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 RG49_RS14480 09de6da6b58575e022e59620ac8a4c4e 161 TIGRFAM TIGR02998 RraA_entero: regulator of ribonuclease activity A 1 161 6.6E-90 T 10-03-2017 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 RG49_RS14480 09de6da6b58575e022e59620ac8a4c4e 161 SUPERFAMILY SSF89562 2 158 7.06E-45 T 10-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein RG49_RS14480 09de6da6b58575e022e59620ac8a4c4e 161 Pfam PF03737 Demethylmenaquinone methyltransferase 5 152 1.3E-36 T 10-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein RG49_RS14480 09de6da6b58575e022e59620ac8a4c4e 161 Hamap MF_00471 Regulator of ribonuclease activity A [rraA]. 1 161 46.865 T 10-03-2017 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 RG49_RS14480 09de6da6b58575e022e59620ac8a4c4e 161 Gene3D G3DSA:3.50.30.40 1 156 3.8E-46 T 10-03-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein RG49_RS14480 09de6da6b58575e022e59620ac8a4c4e 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 1.0E-62 T 10-03-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 252.259 T 10-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 3.3E-17 T 10-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 Gene3D G3DSA:2.40.50.140 49 117 6.5E-37 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 7.2E-223 T 10-03-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 SMART SM00959 5 47 6.9E-18 T 10-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 Gene3D G3DSA:3.40.50.300 132 418 2.7E-106 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 Gene3D G3DSA:1.10.720.10 1 47 1.4E-22 T 10-03-2017 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.6E-32 T 10-03-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 SMART SM00382 170 355 5.0E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 SMART SM00357 52 118 9.6E-19 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 SUPERFAMILY SSF68912 1 46 2.0E-12 T 10-03-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 SUPERFAMILY SSF50249 48 125 9.0E-30 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 SUPERFAMILY SSF52540 90 371 1.49E-68 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15300 e130092e41361244e8362f098cdd0a85 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.3E-22 T 10-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS04315 fa05d62c41789a91e0a75e6318242768 247 Hamap MF_01067 UPF0259 membrane protein YciC [yciC]. 1 247 24.247 T 10-03-2017 IPR009627 Uncharacterised protein family UPF0259 RG49_RS04315 fa05d62c41789a91e0a75e6318242768 247 Pfam PF06790 Uncharacterised protein family (UPF0259) 1 244 1.5E-104 T 10-03-2017 IPR009627 Uncharacterised protein family UPF0259 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 7.8E-18 T 10-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 Gene3D G3DSA:2.40.30.10 209 298 2.7E-37 T 10-03-2017 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 61.284 T 10-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 1.6E-14 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 7.1E-58 T 10-03-2017 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 SUPERFAMILY SSF50447 205 301 1.34E-30 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 2.5E-240 T 10-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 Gene3D G3DSA:3.40.50.300 3 208 5.0E-68 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 SUPERFAMILY SSF52540 6 219 1.94E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 Gene3D G3DSA:2.40.30.10 300 393 8.4E-47 T 10-03-2017 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 SUPERFAMILY SSF50465 298 393 2.62E-36 T 10-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal RG49_RS14195 b837a74346c7ec8a55808938a4589cfa 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 9.5E-34 T 10-03-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 SUPERFAMILY SSF51206 8 136 1.07E-35 T 10-03-2017 IPR018490 Cyclic nucleotide-binding-like RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 30 46 - T 10-03-2017 IPR018488 Cyclic nucleotide-binding, conserved site RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 SMART SM00100 2 122 7.6E-27 T 10-03-2017 IPR000595 Cyclic nucleotide-binding domain RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 166 182 8.8E-11 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 197 8.8E-11 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 Gene3D G3DSA:1.10.10.10 144 207 1.1E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 SUPERFAMILY SSF46785 139 207 3.64E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 SMART SM00419 160 208 4.5E-17 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 6.4E-24 T 10-03-2017 IPR000595 Cyclic nucleotide-binding domain RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 71 89 - T 10-03-2017 IPR018488 Cyclic nucleotide-binding, conserved site RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 ProSitePatterns PS00042 Crp-type HTH domain signature. 168 191 - T 10-03-2017 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 Pfam PF00325 Bacterial regulatory proteins, crp family 166 197 1.7E-15 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS17805 9a58754a5c561c0784b75360a962f090 210 Gene3D G3DSA:2.60.120.10 6 143 1.1E-44 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS13205 b8fbd7e971e10d4cb10475b0eb1206c3 117 Pfam PF13698 Domain of unknown function (DUF4156) 23 115 3.7E-33 T 10-03-2017 IPR025294 Protein of unknown function DUF4156 RG49_RS13205 b8fbd7e971e10d4cb10475b0eb1206c3 117 Gene3D G3DSA:3.50.50.60 16 89 8.4E-4 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 40 92 3.2E-17 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 SMART SM00926 39 93 4.0E-14 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Gene3D G3DSA:2.20.25.90 37 95 2.7E-20 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 2 828 0.0 T 10-03-2017 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 SUPERFAMILY SSF53706 37 700 2.09E-204 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 31 1.3E-4 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Hamap MF_01630 Nitrate reductase [napA]. 1 828 30.887 T 10-03-2017 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Gene3D G3DSA:3.40.50.740 96 178 1.2E-78 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Gene3D G3DSA:3.40.50.740 399 575 1.2E-78 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Gene3D G3DSA:3.40.50.740 621 665 1.2E-78 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Pfam PF01568 Molydopterin dinucleotide binding domain 714 822 1.8E-24 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 SUPERFAMILY SSF50692 688 828 1.06E-41 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Pfam PF00384 Molybdopterin oxidoreductase 96 567 2.6E-92 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Gene3D G3DSA:2.40.40.20 666 828 3.3E-46 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Gene3D G3DSA:3.40.228.10 325 398 2.3E-57 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 Gene3D G3DSA:3.40.228.10 179 291 2.3E-57 T 10-03-2017 RG49_RS24110 2395d09f45f36d54c3298512954eb0fb 828 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 44 61 - T 10-03-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 RG49_RS18740 6430a14f5b78b1e75288bbc6f448e0c5 97 Gene3D G3DSA:3.30.110.60 1 94 3.2E-34 T 10-03-2017 IPR001890 RNA-binding, CRM domain GO:0003723 RG49_RS18740 6430a14f5b78b1e75288bbc6f448e0c5 97 SUPERFAMILY SSF75471 1 95 5.89E-31 T 10-03-2017 IPR001890 RNA-binding, CRM domain GO:0003723 RG49_RS18740 6430a14f5b78b1e75288bbc6f448e0c5 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 97 7.6E-44 T 10-03-2017 IPR017924 RNA-binding protein YhbY GO:0003723 RG49_RS18740 6430a14f5b78b1e75288bbc6f448e0c5 97 SMART SM01103 3 86 4.3E-40 T 10-03-2017 IPR001890 RNA-binding, CRM domain GO:0003723 RG49_RS18740 6430a14f5b78b1e75288bbc6f448e0c5 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 1.7E-22 T 10-03-2017 IPR001890 RNA-binding, CRM domain GO:0003723 RG49_RS18740 6430a14f5b78b1e75288bbc6f448e0c5 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 97 2.0E-44 T 10-03-2017 IPR001890 RNA-binding, CRM domain GO:0003723 RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 SUPERFAMILY SSF53383 2 396 1.44E-117 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 Gene3D G3DSA:3.40.640.10 46 316 3.3E-105 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 10-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 Pfam PF00155 Aminotransferase class I and II 27 392 3.7E-86 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 PRINTS PR00799 Aspartate aminotransferase signature 274 299 1.0E-37 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 PRINTS PR00799 Aspartate aminotransferase signature 342 360 1.0E-37 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 PRINTS PR00799 Aspartate aminotransferase signature 176 195 1.0E-37 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS13760 230f2270f79fa1b72b2a8bb0a2edaa3d 397 PRINTS PR00799 Aspartate aminotransferase signature 207 219 1.0E-37 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS01215 6fd1da280b9a996139cbbeeb6514671a 511 Gene3D G3DSA:1.10.3720.10 313 501 5.4E-15 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS01215 6fd1da280b9a996139cbbeeb6514671a 511 Gene3D G3DSA:1.10.3720.10 9 261 4.6E-17 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS01215 6fd1da280b9a996139cbbeeb6514671a 511 SUPERFAMILY SSF161098 8 256 8.07E-18 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS01215 6fd1da280b9a996139cbbeeb6514671a 511 SUPERFAMILY SSF161098 306 497 2.22E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS01215 6fd1da280b9a996139cbbeeb6514671a 511 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 346 503 1.6E-8 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 Gene3D G3DSA:3.50.50.60 269 357 1.0E-48 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 Gene3D G3DSA:3.50.50.60 3 182 1.0E-48 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 391 1.3E-136 T 10-03-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 Pfam PF01494 FAD binding domain 4 345 1.9E-31 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 5.4E-20 T 10-03-2017 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 5.4E-20 T 10-03-2017 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 5.4E-20 T 10-03-2017 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 5.4E-20 T 10-03-2017 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 10-03-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 SUPERFAMILY SSF51905 4 177 5.83E-61 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20375 d49ffd75186b65703579442fa0127c97 400 SUPERFAMILY SSF51905 268 385 5.83E-61 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS06695 f37ba526a9cfb3de793df8a268ffbf1f 479 Gene3D G3DSA:3.40.50.10140 5 145 1.6E-5 T 10-03-2017 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 RG49_RS06695 f37ba526a9cfb3de793df8a268ffbf1f 479 Pfam PF08357 SEFIR domain 3 122 7.5E-16 T 10-03-2017 IPR013568 SEFIR domain RG49_RS10765 57238e17e78eba497abf36bed860a912 304 SUPERFAMILY SSF46785 6 113 7.57E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS10765 57238e17e78eba497abf36bed860a912 304 SUPERFAMILY SSF53850 90 296 2.61E-46 T 10-03-2017 RG49_RS10765 57238e17e78eba497abf36bed860a912 304 Gene3D G3DSA:1.10.10.10 5 84 4.3E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS10765 57238e17e78eba497abf36bed860a912 304 Gene3D G3DSA:3.40.190.10 180 258 5.7E-20 T 10-03-2017 RG49_RS10765 57238e17e78eba497abf36bed860a912 304 Gene3D G3DSA:3.40.190.10 93 179 7.8E-25 T 10-03-2017 RG49_RS10765 57238e17e78eba497abf36bed860a912 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 3.7E-20 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS10765 57238e17e78eba497abf36bed860a912 304 Pfam PF03466 LysR substrate binding domain 89 293 2.5E-44 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS10765 57238e17e78eba497abf36bed860a912 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.3E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS10765 57238e17e78eba497abf36bed860a912 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.3E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS10765 57238e17e78eba497abf36bed860a912 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.3E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS09995 94f699774f8cf3473081aae58f1c9594 189 Pfam PF00011 Hsp20/alpha crystallin family 85 188 9.5E-29 T 10-03-2017 IPR002068 Alpha crystallin/Hsp20 domain RG49_RS09995 94f699774f8cf3473081aae58f1c9594 189 Gene3D G3DSA:2.60.40.790 39 187 9.4E-48 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS09995 94f699774f8cf3473081aae58f1c9594 189 SUPERFAMILY SSF49764 49 181 9.63E-41 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS25215 21b85f025a658d2808d5a809e9e4ef4f 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 10 134 3.9E-26 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS25215 21b85f025a658d2808d5a809e9e4ef4f 152 SUPERFAMILY SSF55804 11 136 1.07E-31 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS25215 21b85f025a658d2808d5a809e9e4ef4f 152 Gene3D G3DSA:3.40.930.10 10 136 1.6E-33 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS20060 4c3f9a51974bda1af9fa1b43ada80cf7 418 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 418 1.2E-225 T 10-03-2017 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 RG49_RS20060 4c3f9a51974bda1af9fa1b43ada80cf7 418 SUPERFAMILY SSF103473 9 406 2.49E-32 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS20060 4c3f9a51974bda1af9fa1b43ada80cf7 418 Gene3D G3DSA:1.20.1250.20 200 405 1.1E-18 T 10-03-2017 RG49_RS20060 4c3f9a51974bda1af9fa1b43ada80cf7 418 Gene3D G3DSA:1.20.1250.20 6 121 2.8E-8 T 10-03-2017 RG49_RS20060 4c3f9a51974bda1af9fa1b43ada80cf7 418 Hamap MF_02049 Nucleoside permease NupG [nupG]. 1 417 47.371 T 10-03-2017 IPR033667 Nucleoside permease NupG GO:0005887|GO:1901642 RG49_RS20060 4c3f9a51974bda1af9fa1b43ada80cf7 418 Pfam PF03825 Nucleoside H+ symporter 1 406 9.1E-189 T 10-03-2017 RG49_RS02695 ab8293ef18a949b9cb18fcb7568d7b7b 516 Pfam PF00589 Phage integrase family 207 376 2.0E-6 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02695 ab8293ef18a949b9cb18fcb7568d7b7b 516 Gene3D G3DSA:1.10.443.10 203 377 9.3E-16 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02695 ab8293ef18a949b9cb18fcb7568d7b7b 516 SUPERFAMILY SSF56349 195 378 9.12E-15 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 150 1.7E-59 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 7.6E-48 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 7.6E-48 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 7.6E-48 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 7.6E-48 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 7.6E-48 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 SUPERFAMILY SSF51735 3 166 1.04E-66 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01090 adec9c8c296a076912033969d932bc85 331 PIRSF PIRSF000149 1 331 7.9E-137 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 Gene3D G3DSA:3.30.360.10 159 314 1.4E-87 T 10-03-2017 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 3.8E-134 T 10-03-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 Gene3D G3DSA:3.40.50.720 1 158 5.1E-78 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01090 adec9c8c296a076912033969d932bc85 331 SMART SM00846 3 150 4.8E-95 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 2.1E-72 T 10-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 10-03-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01090 adec9c8c296a076912033969d932bc85 331 SUPERFAMILY SSF55347 149 312 2.43E-82 T 10-03-2017 RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 SUPERFAMILY SSF54631 290 424 1.3E-26 T 10-03-2017 RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 Pfam PF03471 Transporter associated domain 440 516 2.4E-19 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 Gene3D G3DSA:3.30.465.10 417 516 2.6E-26 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 SMART SM01091 439 518 3.0E-25 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 Pfam PF00571 CBS domain 302 358 3.0E-4 T 10-03-2017 IPR000644 CBS domain RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 Pfam PF00571 CBS domain 372 422 9.7E-7 T 10-03-2017 IPR000644 CBS domain RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 Pfam PF03741 Integral membrane protein TerC family 14 203 2.2E-50 T 10-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 Gene3D G3DSA:3.10.580.10 288 416 7.1E-15 T 10-03-2017 RG49_RS24870 489522a7256d2bc0f499837531aec43d 527 SUPERFAMILY SSF56176 437 521 1.58E-21 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS17850 32748b567785b5ea6d93880ce1dcba04 601 Gene3D G3DSA:3.40.50.720 395 531 9.8E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17850 32748b567785b5ea6d93880ce1dcba04 601 Pfam PF00999 Sodium/hydrogen exchanger family 11 373 3.6E-68 T 10-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 RG49_RS17850 32748b567785b5ea6d93880ce1dcba04 601 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 283 3.7E-94 T 10-03-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 RG49_RS17850 32748b567785b5ea6d93880ce1dcba04 601 Hamap MF_01412 Glutathione-regulated potassium-efflux system protein KefB [kefB]. 2 598 47.418 T 10-03-2017 IPR020884 Glutathione-regulated potassium-efflux system protein KefB GO:0005886|GO:0006813|GO:0015503 RG49_RS17850 32748b567785b5ea6d93880ce1dcba04 601 SUPERFAMILY SSF51735 402 529 1.69E-29 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17850 32748b567785b5ea6d93880ce1dcba04 601 Pfam PF02254 TrkA-N domain 403 514 9.4E-25 T 10-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 SUPERFAMILY SSF50104 2 114 5.52E-48 T 10-03-2017 IPR008991 Translation protein SH3-like domain RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 10-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 10-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 10-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.3E-53 T 10-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 Pfam PF01245 Ribosomal protein L19 3 113 3.7E-50 T 10-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 10-03-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 PIRSF PIRSF002191 1 115 1.1E-50 T 10-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS22000 f5a64710e99eaf586d30566f0129af5e 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 30.739 T 10-03-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 SUPERFAMILY SSF55021 336 423 2.75E-28 T 10-03-2017 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 SUPERFAMILY SSF55021 420 512 1.6E-25 T 10-03-2017 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 419 2.7E-29 T 10-03-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 425 512 1.3E-26 T 10-03-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 Gene3D G3DSA:3.40.50.1100 81 333 1.3E-77 T 10-03-2017 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 15 512 7.9E-270 T 10-03-2017 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 SUPERFAMILY SSF53686 14 365 1.31E-100 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 10-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 Gene3D G3DSA:3.40.1020.10 339 512 1.5E-56 T 10-03-2017 RG49_RS15355 4dc325fe6b3788855c5faaf3514c2344 514 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 316 1.9E-76 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS01255 12477223007b338aac9b6293cf451878 406 Pfam PF00202 Aminotransferase class-III 22 395 1.7E-125 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS01255 12477223007b338aac9b6293cf451878 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 397 1.7E-169 T 10-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 RG49_RS01255 12477223007b338aac9b6293cf451878 406 Hamap MF_01173 Succinylornithine transaminase [astC]. 1 406 77.807 T 10-03-2017 IPR026330 Succinylornithine transaminase GO:0006527|GO:0006593|GO:0043825 KEGG: 00330+2.6.1.81 RG49_RS01255 12477223007b338aac9b6293cf451878 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 398 45.509 T 10-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 RG49_RS01255 12477223007b338aac9b6293cf451878 406 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 5 401 7.4E-229 T 10-03-2017 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 RG49_RS01255 12477223007b338aac9b6293cf451878 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS01255 12477223007b338aac9b6293cf451878 406 Gene3D G3DSA:3.90.1150.10 8 57 3.0E-36 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS01255 12477223007b338aac9b6293cf451878 406 Gene3D G3DSA:3.90.1150.10 304 398 3.0E-36 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS01255 12477223007b338aac9b6293cf451878 406 SUPERFAMILY SSF53383 13 397 7.4E-128 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS01255 12477223007b338aac9b6293cf451878 406 Gene3D G3DSA:3.40.640.10 58 300 2.0E-92 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS01255 12477223007b338aac9b6293cf451878 406 PIRSF PIRSF000521 26 400 7.1E-46 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 SUPERFAMILY SSF47413 6 59 5.63E-9 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 Gene3D G3DSA:1.10.260.40 5 58 2.5E-11 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 Pfam PF01381 Helix-turn-helix 7 59 5.2E-9 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 Gene3D G3DSA:3.40.50.620 63 230 2.9E-52 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 66 136 5.3E-20 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 PIRSF PIRSF004776 2 410 4.2E-214 T 10-03-2017 IPR016429 Bifunctional transcriptional regulator NadR GO:0045892 KEGG: 00760+2.7.7.1+2.7.1.22 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 TIGRFAM TIGR01526 nadR_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 64 395 2.4E-166 T 10-03-2017 IPR006417 Nicotinamide-nucleotide adenylyltransferase GO:0003677|GO:0006355|GO:0006810|GO:0019363 KEGG: 00760+2.7.7.1+2.7.1.22 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 Pfam PF13521 AAA domain 234 394 4.3E-31 T 10-03-2017 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 SMART SM00530 6 62 7.0E-8 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 SUPERFAMILY SSF52540 232 386 7.49E-27 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 SUPERFAMILY SSF52374 66 229 1.66E-18 T 10-03-2017 RG49_RS11965 77a7c27be2ad0b4068b2807d43a045a2 410 Gene3D G3DSA:3.40.50.300 231 400 2.4E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 Pfam PF13193 AMP-binding enzyme C-terminal domain 366 424 1.2E-6 T 10-03-2017 IPR025110 AMP-binding enzyme C-terminal domain RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 ProSitePatterns PS00455 Putative AMP-binding domain signature. 139 150 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 SUPERFAMILY SSF56801 8 449 2.49E-93 T 10-03-2017 RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 Gene3D G3DSA:2.30.38.10 291 350 3.0E-8 T 10-03-2017 RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 Pfam PF00501 AMP-binding enzyme 13 355 5.9E-54 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 30 443 1.4E-112 T 10-03-2017 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 Gene3D G3DSA:3.40.50.980 13 147 3.1E-21 T 10-03-2017 RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 Gene3D G3DSA:3.30.300.30 353 447 1.0E-15 T 10-03-2017 RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 Gene3D G3DSA:3.40.50.980 148 290 5.8E-24 T 10-03-2017 RG49_RS23790 e2cadeb535c1b180382eb1e160a83402 451 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 4 446 37.388 T 10-03-2017 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 RG49_RS01785 3b8b75ad5cd020ba6c360a123b86b45a 215 Gene3D G3DSA:3.30.420.10 12 209 2.6E-58 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS01785 3b8b75ad5cd020ba6c360a123b86b45a 215 Pfam PF00929 Exonuclease 20 194 3.7E-39 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS01785 3b8b75ad5cd020ba6c360a123b86b45a 215 SUPERFAMILY SSF53098 13 207 1.3E-56 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS01785 3b8b75ad5cd020ba6c360a123b86b45a 215 TIGRFAM TIGR01298 RNaseT: ribonuclease T 10 208 8.6E-116 T 10-03-2017 IPR005987 Ribonuclease T GO:0004540|GO:0006396 RG49_RS01785 3b8b75ad5cd020ba6c360a123b86b45a 215 Hamap MF_00157 Ribonuclease T [rnt]. 1 215 117.887 T 10-03-2017 IPR005987 Ribonuclease T GO:0004540|GO:0006396 RG49_RS01785 3b8b75ad5cd020ba6c360a123b86b45a 215 SMART SM00479 18 203 6.0E-42 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS04050 80f9398ec78d7f51d888303374d3524f 185 Pfam PF01381 Helix-turn-helix 13 66 1.9E-14 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS04050 80f9398ec78d7f51d888303374d3524f 185 SMART SM00530 11 66 1.1E-14 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS04050 80f9398ec78d7f51d888303374d3524f 185 SUPERFAMILY SSF51182 51 183 3.41E-30 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS04050 80f9398ec78d7f51d888303374d3524f 185 Gene3D G3DSA:1.10.260.40 7 74 5.7E-22 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS04050 80f9398ec78d7f51d888303374d3524f 185 Gene3D G3DSA:2.60.120.10 75 183 2.6E-24 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS04050 80f9398ec78d7f51d888303374d3524f 185 SUPERFAMILY SSF47413 8 73 2.68E-16 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS04050 80f9398ec78d7f51d888303374d3524f 185 Pfam PF07883 Cupin domain 111 178 1.7E-17 T 10-03-2017 IPR013096 Cupin 2, conserved barrel RG49_RS08560 ec07e7a15db81b8bf4d37c8b69656dbf 123 SUPERFAMILY SSF46689 17 111 8.42E-8 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08560 ec07e7a15db81b8bf4d37c8b69656dbf 123 Pfam PF13551 Winged helix-turn helix 11 74 3.9E-19 T 10-03-2017 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 SUPERFAMILY SSF53150 117 269 1.57E-42 T 10-03-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 SMART SM00533 286 591 9.7E-111 T 10-03-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Pfam PF05188 MutS domain II 131 256 5.3E-33 T 10-03-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 10 845 25.477 T 10-03-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 SUPERFAMILY SSF55271 6 116 4.58E-43 T 10-03-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Gene3D G3DSA:3.40.50.300 567 797 1.6E-82 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 850 0.0 T 10-03-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 SUPERFAMILY SSF48334 270 566 1.96E-90 T 10-03-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Gene3D G3DSA:3.40.1170.10 5 123 2.6E-52 T 10-03-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Pfam PF05192 MutS domain III 272 559 5.1E-41 T 10-03-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Gene3D G3DSA:1.10.1420.10 319 477 4.1E-56 T 10-03-2017 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 SMART SM00534 607 794 2.5E-123 T 10-03-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Pfam PF01624 MutS domain I 11 122 4.0E-43 T 10-03-2017 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 688 704 - T 10-03-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 SUPERFAMILY SSF52540 567 798 8.38E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Pfam PF05190 MutS family domain IV 428 517 1.5E-28 T 10-03-2017 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Pfam PF00488 MutS domain V 610 797 3.4E-88 T 10-03-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS21405 c5034bb161d1ccf4113218952d6bb393 853 Gene3D G3DSA:3.30.420.110 129 258 5.7E-43 T 10-03-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 RG49_RS07820 0b6ffb4b5e917e71815fd78b961f8398 512 Gene3D G3DSA:3.60.110.10 216 478 9.1E-22 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS07820 0b6ffb4b5e917e71815fd78b961f8398 512 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 10 495 24.1 T 10-03-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 RG49_RS07820 0b6ffb4b5e917e71815fd78b961f8398 512 Pfam PF00795 Carbon-nitrogen hydrolase 224 478 4.3E-39 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS07820 0b6ffb4b5e917e71815fd78b961f8398 512 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 63 458 1.8E-123 T 10-03-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 RG49_RS07820 0b6ffb4b5e917e71815fd78b961f8398 512 SUPERFAMILY SSF56317 216 490 2.35E-36 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS11530 e764f6b90113b389894641f3156cda8d 536 SUPERFAMILY SSF161098 12 265 5.33E-43 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS11530 e764f6b90113b389894641f3156cda8d 536 SUPERFAMILY SSF161098 289 527 1.31E-34 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS11530 e764f6b90113b389894641f3156cda8d 536 Gene3D G3DSA:1.10.3720.10 292 531 1.8E-32 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS11530 e764f6b90113b389894641f3156cda8d 536 Gene3D G3DSA:1.10.3720.10 18 267 7.6E-36 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS11530 e764f6b90113b389894641f3156cda8d 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 267 2.4E-11 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS11530 e764f6b90113b389894641f3156cda8d 536 TIGRFAM TIGR01253 thiP: thiamine/thiamine pyrophosphate ABC transporter, permease protein 8 525 9.0E-298 T 10-03-2017 IPR005947 Thiamine ABC transporter, permease protein GO:0005215|GO:0015888|GO:0016021 RG49_RS16945 2b4f5dc375d165b36bcd059ce2986a5b 466 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 269 290 - T 10-03-2017 IPR021115 Pyridoxal-phosphate binding site GO:0016831 RG49_RS16945 2b4f5dc375d165b36bcd059ce2986a5b 466 SUPERFAMILY SSF53383 6 451 1.16E-132 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS16945 2b4f5dc375d165b36bcd059ce2986a5b 466 Gene3D G3DSA:3.40.640.10 75 321 2.0E-24 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS16945 2b4f5dc375d165b36bcd059ce2986a5b 466 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 33 383 1.5E-114 T 10-03-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 RG49_RS16945 2b4f5dc375d165b36bcd059ce2986a5b 466 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 16 448 2.8E-209 T 10-03-2017 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 RG49_RS04030 e5db5e4d81efa1127717b7285c13d6b5 421 SUPERFAMILY SSF53383 23 420 4.08E-130 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS04030 e5db5e4d81efa1127717b7285c13d6b5 421 Pfam PF00202 Aminotransferase class-III 22 419 1.3E-127 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS04030 e5db5e4d81efa1127717b7285c13d6b5 421 Gene3D G3DSA:3.40.640.10 58 303 1.4E-83 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS04030 e5db5e4d81efa1127717b7285c13d6b5 421 Gene3D G3DSA:3.90.1150.10 304 420 6.4E-41 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS04030 e5db5e4d81efa1127717b7285c13d6b5 421 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 8 421 7.3E-230 T 10-03-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 RG49_RS04030 e5db5e4d81efa1127717b7285c13d6b5 421 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 SMART SM00345 13 72 9.2E-26 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 SUPERFAMILY SSF46785 2 76 2.37E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 Pfam PF07729 FCD domain 96 219 2.0E-18 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 Gene3D G3DSA:1.20.120.530 96 225 5.1E-22 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 SMART SM00895 96 220 5.6E-16 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.2E-7 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.2E-7 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 Gene3D G3DSA:1.10.10.10 5 77 3.8E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 SUPERFAMILY SSF48008 94 222 8.11E-21 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS19235 022fb3f73dae00ef40aaa4e42ab852b8 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 1.5E-22 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS23365 1de40c116bd26f06f23127c4d2cb796e 94 Pfam PF04175 Protein of unknown function (DUF406) 3 94 6.7E-39 T 10-03-2017 IPR005272 Conserved hypothetical protein CHP00743 RG49_RS23365 1de40c116bd26f06f23127c4d2cb796e 94 TIGRFAM TIGR00743 TIGR00743: conserved hypothetical protein 1 94 3.9E-47 T 10-03-2017 IPR005272 Conserved hypothetical protein CHP00743 RG49_RS23365 1de40c116bd26f06f23127c4d2cb796e 94 Gene3D G3DSA:3.30.70.860 23 94 3.4E-35 T 10-03-2017 RG49_RS23320 4d967f835c8efed64743cb870a1b3d2c 442 Gene3D G3DSA:3.40.50.1100 180 438 3.3E-45 T 10-03-2017 RG49_RS23320 4d967f835c8efed64743cb870a1b3d2c 442 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 108 122 - T 10-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 RG49_RS23320 4d967f835c8efed64743cb870a1b3d2c 442 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 9 438 4.3E-246 T 10-03-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 RG49_RS23320 4d967f835c8efed64743cb870a1b3d2c 442 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 442 281.325 T 10-03-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 RG49_RS23320 4d967f835c8efed64743cb870a1b3d2c 442 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 402 1.5E-60 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS23320 4d967f835c8efed64743cb870a1b3d2c 442 SUPERFAMILY SSF53686 73 435 2.19E-55 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 Gene3D G3DSA:1.20.1270.50 286 378 4.8E-6 T 10-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 SMART SM00872 279 357 5.8E-18 T 10-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 SUPERFAMILY SSF88713 6 272 5.19E-55 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 386 843 8.0E-28 T 10-03-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 Gene3D G3DSA:3.20.110.10 6 273 8.5E-47 T 10-03-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 7 269 2.6E-39 T 10-03-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 SUPERFAMILY SSF88688 286 378 9.15E-8 T 10-03-2017 IPR028995 Glycoside hydrolase families 57/38, central domain RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 Pfam PF09261 Alpha mannosidase middle domain 280 355 3.0E-7 T 10-03-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 RG49_RS07395 6de0114ef053eb768d02c8e101cfd3ec 877 SUPERFAMILY SSF74650 375 876 2.61E-74 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 Pfam PF13247 4Fe-4S dicluster domain 59 153 2.0E-29 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 Pfam PF12800 4Fe-4S binding domain 12 25 0.0022 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 SUPERFAMILY SSF54862 3 198 6.59E-71 T 10-03-2017 RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 Gene3D G3DSA:3.30.70.20 75 118 1.8E-26 T 10-03-2017 RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 Gene3D G3DSA:3.30.70.20 119 171 2.6E-18 T 10-03-2017 RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 4 163 7.4E-80 T 10-03-2017 IPR014297 Dimethylsulphoxide reductase, chain B RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 Gene3D G3DSA:3.30.70.20 4 74 6.5E-18 T 10-03-2017 RG49_RS02130 1012a7f951bc4856368ad18a8de3478a 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS06615 9ffd4987d03db61710ee4b930a27b9df 119 Pfam PF04965 Gene 25-like lysozyme 19 96 9.5E-14 T 10-03-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD RG49_RS06615 9ffd4987d03db61710ee4b930a27b9df 119 Gene3D G3DSA:3.10.450.40 9 116 5.2E-35 T 10-03-2017 RG49_RS06615 9ffd4987d03db61710ee4b930a27b9df 119 SUPERFAMILY SSF160719 12 111 5.62E-27 T 10-03-2017 RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 Gene3D G3DSA:3.40.50.300 448 597 2.8E-7 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 SMART SM00487 16 286 0.0022 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 Gene3D G3DSA:3.40.50.300 8 116 2.6E-21 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 Gene3D G3DSA:3.40.50.300 190 233 2.6E-21 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 SMART SM00491 474 603 3.8E-55 T 10-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 Pfam PF13307 Helicase C-terminal domain 459 616 1.7E-34 T 10-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 SUPERFAMILY SSF52540 13 232 1.22E-28 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 SUPERFAMILY SSF52540 573 597 2.52E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 SUPERFAMILY SSF52540 38 88 2.52E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 SUPERFAMILY SSF52540 477 542 2.52E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00935 061b629dd13e7884fdf52b89b17b4498 636 Pfam PF04851 Type III restriction enzyme, res subunit 18 232 8.0E-6 T 10-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 SMART SM00487 1 185 2.4E-20 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 SUPERFAMILY SSF52540 237 363 1.36E-38 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 SUPERFAMILY SSF52540 50 169 1.36E-38 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 Gene3D G3DSA:3.40.50.300 3 155 1.1E-31 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 Gene3D G3DSA:3.40.50.300 238 355 3.7E-22 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 SMART SM00490 263 345 7.1E-10 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 SUPERFAMILY SSF57829 424 465 4.76E-7 T 10-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 Pfam PF00271 Helicase conserved C-terminal domain 241 343 9.3E-13 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS24220 681d45009ca4e9951c089933f991d05e 586 Pfam PF04851 Type III restriction enzyme, res subunit 3 154 9.6E-26 T 10-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 RG49_RS12060 0cea5116412d9fea235b3066fe17030e 225 Gene3D G3DSA:1.10.150.240 15 90 3.9E-18 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS12060 0cea5116412d9fea235b3066fe17030e 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 195 2.3E-9 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS12060 0cea5116412d9fea235b3066fe17030e 225 SUPERFAMILY SSF56784 3 222 2.61E-47 T 10-03-2017 IPR023214 HAD-like domain RG49_RS12060 0cea5116412d9fea235b3066fe17030e 225 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 221 5.2E-75 T 10-03-2017 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 RG49_RS12060 0cea5116412d9fea235b3066fe17030e 225 Gene3D G3DSA:3.40.50.1000 91 223 1.5E-44 T 10-03-2017 IPR023214 HAD-like domain RG49_RS12060 0cea5116412d9fea235b3066fe17030e 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 82 194 1.5E-20 T 10-03-2017 IPR023214 HAD-like domain RG49_RS12060 0cea5116412d9fea235b3066fe17030e 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 189 2.0E-17 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 218 229 - T 10-03-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 SUPERFAMILY SSF143243 13 196 7.06E-45 T 10-03-2017 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 Gene3D G3DSA:1.10.645.10 168 378 6.6E-53 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 154 2.0E-31 T 10-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 40 155 7.9E-22 T 10-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 444 523 1.9E-11 T 10-03-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 297 447 4.0E-22 T 10-03-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 Pfam PF00374 Nickel-dependent hydrogenase 220 288 5.7E-13 T 10-03-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 SUPERFAMILY SSF56762 195 523 1.1E-101 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22715 af13eab8cce07d308be5b201378ab2f6 555 Gene3D G3DSA:1.10.645.10 379 522 1.3E-32 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 SUPERFAMILY SSF158472 188 236 2.88E-9 T 10-03-2017 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 SMART SM00387 349 461 5.6E-35 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 460 4.8E-19 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 SUPERFAMILY SSF55874 293 459 8.12E-40 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 SMART SM00304 187 239 6.1E-14 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 Gene3D G3DSA:1.10.287.130 232 290 3.5E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 Pfam PF00672 HAMP domain 168 235 8.5E-17 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 SUPERFAMILY SSF47384 223 304 5.89E-15 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 304 3.5E-13 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 2.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 2.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 2.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 2.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 SMART SM00388 240 304 3.0E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24785 0afded3e527f8d8947fc9c1aed68bf55 467 Gene3D G3DSA:3.30.565.10 291 461 2.0E-38 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 Gene3D G3DSA:1.10.540.10 95 234 1.8E-32 T 10-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 Gene3D G3DSA:2.40.110.10 237 348 2.0E-17 T 10-03-2017 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 Gene3D G3DSA:1.20.140.10 349 505 1.0E-23 T 10-03-2017 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 SUPERFAMILY SSF56645 117 355 6.68E-47 T 10-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 SUPERFAMILY SSF47203 360 515 5.48E-21 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 237 328 9.1E-9 T 10-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 360 504 3.8E-12 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 147 232 5.8E-16 T 10-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 RG49_RS10575 8d032e73dd5e90940f93152341cda159 814 Pfam PF09317 Domain of unknown function (DUF1974) 514 792 1.2E-117 T 10-03-2017 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 RG49_RS03715 df3f15b3f86bda18bdc66fe91a77dbb9 44 SUPERFAMILY SSF46934 5 36 3.03E-5 T 10-03-2017 IPR009060 UBA-like GO:0005515 RG49_RS03715 df3f15b3f86bda18bdc66fe91a77dbb9 44 Gene3D G3DSA:1.10.8.10 5 35 4.0E-4 T 10-03-2017 RG49_RS03715 df3f15b3f86bda18bdc66fe91a77dbb9 44 Pfam PF14555 UBA-like domain 6 35 3.5E-5 T 10-03-2017 RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 SMART SM00100 30 151 2.9E-22 T 10-03-2017 IPR000595 Cyclic nucleotide-binding domain RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 SMART SM00419 187 235 2.8E-13 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 Pfam PF00027 Cyclic nucleotide-binding domain 51 132 9.8E-16 T 10-03-2017 IPR000595 Cyclic nucleotide-binding domain RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 209 224 2.2E-12 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 209 2.2E-12 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 SUPERFAMILY SSF46785 165 246 2.11E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 Gene3D G3DSA:2.60.120.10 18 169 1.6E-40 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 Gene3D G3DSA:1.10.10.10 170 244 6.3E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 Pfam PF13545 Crp-like helix-turn-helix domain 168 242 2.2E-16 T 10-03-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 SUPERFAMILY SSF51206 23 162 1.27E-31 T 10-03-2017 IPR018490 Cyclic nucleotide-binding-like RG49_RS03865 1292da009aa32cef15c5f4f65ad64f77 250 ProSitePatterns PS00042 Crp-type HTH domain signature. 195 218 - T 10-03-2017 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 Gene3D G3DSA:3.30.420.40 220 465 4.3E-41 T 10-03-2017 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 225 418 7.9E-23 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 SUPERFAMILY SSF53067 218 455 3.29E-43 T 10-03-2017 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 121 216 8.1E-7 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 110 1.0E-11 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 SUPERFAMILY SSF53067 4 216 6.64E-37 T 10-03-2017 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 Gene3D G3DSA:3.30.420.40 1 117 3.6E-22 T 10-03-2017 RG49_RS21175 f585bfee6898d20951cb16e2bd3d11e3 492 Gene3D G3DSA:3.30.420.40 120 217 4.1E-13 T 10-03-2017 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 Gene3D G3DSA:1.20.1330.10 54 170 9.6E-59 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 Gene3D G3DSA:1.20.1330.10 458 512 9.6E-59 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 Pfam PF00700 Bacterial flagellin C-terminal helical region 470 555 3.6E-30 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 Pfam PF12445 Flagellin protein 337 461 2.1E-25 T 10-03-2017 IPR032826 Flagellin, H7-serospecific domain RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 PRINTS PR00207 Flagellin signature 37 54 2.5E-31 T 10-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 PRINTS PR00207 Flagellin signature 111 134 2.5E-31 T 10-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 PRINTS PR00207 Flagellin signature 76 95 2.5E-31 T 10-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 8.4E-45 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 SUPERFAMILY SSF64518 277 332 1.44E-105 T 10-03-2017 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 SUPERFAMILY SSF64518 363 556 1.44E-105 T 10-03-2017 RG49_RS19075 d8ab60a996f71cfa4fce1a4bed96db2c 556 SUPERFAMILY SSF64518 1 242 1.44E-105 T 10-03-2017 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 256 453 28.398 T 10-03-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 Gene3D G3DSA:3.20.20.70 260 446 2.3E-60 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 4 255 35.316 T 10-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 SUPERFAMILY SSF51366 258 451 1.88E-55 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 SUPERFAMILY SSF51366 2 253 1.88E-85 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 258 448 3.0E-63 T 10-03-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 Pfam PF00218 Indole-3-glycerol phosphate synthase 6 252 1.1E-99 T 10-03-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 Gene3D G3DSA:3.20.20.70 2 259 3.4E-104 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS04275 f7865ba4aca1dcee0fe409b75a7657e2 453 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 69 - T 10-03-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Pfam PF02780 Transketolase, C-terminal domain 495 610 2.8E-27 T 10-03-2017 IPR033248 Transketolase, C-terminal domain RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 620 46.662 T 10-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 ProSitePatterns PS00801 Transketolase signature 1. 36 55 - T 10-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Pfam PF02779 Transketolase, pyrimidine binding domain 320 480 5.1E-40 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 SUPERFAMILY SSF52922 491 619 1.83E-32 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Gene3D G3DSA:3.40.50.920 496 619 1.6E-35 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 SUPERFAMILY SSF52518 10 199 3.8E-75 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 SUPERFAMILY SSF52518 243 381 3.8E-75 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 10-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 12 282 1.0E-116 T 10-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 SMART SM00861 319 484 8.7E-69 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 SUPERFAMILY SSF52518 317 504 9.36E-58 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Gene3D G3DSA:3.40.50.970 335 495 1.9E-34 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 11 620 0.0 T 10-03-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Gene3D G3DSA:3.40.50.970 242 334 2.7E-74 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS09030 4972d29224db60427f2e8050ccd576c8 620 Gene3D G3DSA:3.40.50.970 26 201 2.7E-74 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23930 59d36ff0422a3a4e1b66e8be929c4ce8 376 Gene3D G3DSA:1.10.620.20 3 340 4.4E-129 T 10-03-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 RG49_RS23930 59d36ff0422a3a4e1b66e8be929c4ce8 376 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 10-03-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23930 59d36ff0422a3a4e1b66e8be929c4ce8 376 Pfam PF00268 Ribonucleotide reductase, small chain 32 332 5.9E-50 T 10-03-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23930 59d36ff0422a3a4e1b66e8be929c4ce8 376 SUPERFAMILY SSF47240 3 340 4.33E-117 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 SMART SM00382 161 304 6.5E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 Pfam PF00158 Sigma-54 interaction domain 141 307 1.8E-71 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 Gene3D G3DSA:1.10.10.60 398 440 7.7E-19 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 SUPERFAMILY SSF52540 141 385 1.31E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 Pfam PF00072 Response regulator receiver domain 8 117 2.3E-30 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 SMART SM00448 6 117 2.0E-38 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 SUPERFAMILY SSF52172 4 185 5.12E-48 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 Gene3D G3DSA:3.40.50.300 139 313 2.1E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 SUPERFAMILY SSF46689 399 440 1.43E-9 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 Pfam PF02954 Bacterial regulatory protein, Fis family 403 441 3.6E-15 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 425 441 2.9E-12 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 408 425 2.9E-12 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 Gene3D G3DSA:1.10.8.60 314 389 6.3E-29 T 10-03-2017 RG49_RS14060 30bd5c963105de755b89ed32247b10cd 441 Gene3D G3DSA:3.40.50.2300 2 126 1.0E-39 T 10-03-2017 RG49_RS18255 9407593aea3ed3cbf9610c84d0a3a88c 393 SUPERFAMILY SSF161098 181 374 2.09E-28 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18255 9407593aea3ed3cbf9610c84d0a3a88c 393 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 388 1.7E-14 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18255 9407593aea3ed3cbf9610c84d0a3a88c 393 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 84 147 4.7E-17 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS18255 9407593aea3ed3cbf9610c84d0a3a88c 393 SUPERFAMILY SSF161098 83 154 8.63E-14 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18255 9407593aea3ed3cbf9610c84d0a3a88c 393 Gene3D G3DSA:1.10.3720.10 182 388 3.8E-37 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18255 9407593aea3ed3cbf9610c84d0a3a88c 393 Gene3D G3DSA:1.10.3720.10 82 153 6.5E-15 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS00780 9260eebf39ee77c1e7168e2080269e60 877 Pfam PF02470 MlaD protein 394 455 8.5E-6 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS00780 9260eebf39ee77c1e7168e2080269e60 877 Pfam PF02470 MlaD protein 280 351 3.3E-8 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS00780 9260eebf39ee77c1e7168e2080269e60 877 Pfam PF02470 MlaD protein 747 810 3.0E-8 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS00780 9260eebf39ee77c1e7168e2080269e60 877 Pfam PF02470 MlaD protein 636 724 5.5E-10 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS00780 9260eebf39ee77c1e7168e2080269e60 877 Pfam PF02470 MlaD protein 46 137 9.5E-17 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS00780 9260eebf39ee77c1e7168e2080269e60 877 Pfam PF02470 MlaD protein 163 220 2.7E-6 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 399 629 2.4E-79 T 10-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Gene3D G3DSA:3.30.559.10 389 630 5.6E-83 T 10-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Gene3D G3DSA:4.10.320.10 319 367 2.0E-22 T 10-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Pfam PF00364 Biotin-requiring enzyme 207 277 4.1E-22 T 10-03-2017 IPR000089 Biotin/lipoyl attachment RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Pfam PF00364 Biotin-requiring enzyme 107 176 6.2E-23 T 10-03-2017 IPR000089 Biotin/lipoyl attachment RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Pfam PF00364 Biotin-requiring enzyme 4 73 1.8E-21 T 10-03-2017 IPR000089 Biotin/lipoyl attachment RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 SUPERFAMILY SSF51230 1 93 5.23E-23 T 10-03-2017 IPR011053 Single hybrid motif RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 SUPERFAMILY SSF52777 388 629 8.45E-80 T 10-03-2017 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Pfam PF02817 e3 binding domain 327 362 2.1E-15 T 10-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Gene3D G3DSA:2.40.50.100 107 182 2.8E-23 T 10-03-2017 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 10-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 180 630 3.1E-243 T 10-03-2017 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 128 157 - T 10-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 229 258 - T 10-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Gene3D G3DSA:2.40.50.100 1 94 5.8E-22 T 10-03-2017 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 Gene3D G3DSA:2.40.50.100 207 298 3.0E-22 T 10-03-2017 RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 SUPERFAMILY SSF51230 206 298 1.31E-23 T 10-03-2017 IPR011053 Single hybrid motif RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 SUPERFAMILY SSF51230 105 197 3.4E-24 T 10-03-2017 IPR011053 Single hybrid motif RG49_RS11280 71a490c733e5f9df7d3b5b5c0a876a35 630 SUPERFAMILY SSF47005 321 366 2.22E-13 T 10-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS09070 f85fab297748e29ce7fcec9f4e5e81c4 179 Gene3D G3DSA:2.60.40.1620 43 177 3.0E-70 T 10-03-2017 IPR021658 Domain of unknown function DUF3251 RG49_RS09070 f85fab297748e29ce7fcec9f4e5e81c4 179 Pfam PF11622 Protein of unknown function (DUF3251) 20 176 3.2E-80 T 10-03-2017 IPR021658 Domain of unknown function DUF3251 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 SMART SM01217 685 754 8.0E-32 T 10-03-2017 IPR026891 Fibronectin type III-like domain RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 Gene3D G3DSA:3.20.20.300 35 366 7.6E-104 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 46 352 3.1E-101 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 Pfam PF14310 Fibronectin type III-like domain 686 754 3.1E-23 T 10-03-2017 IPR026891 Fibronectin type III-like domain RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 SUPERFAMILY SSF52279 395 464 3.66E-58 T 10-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 SUPERFAMILY SSF52279 495 651 3.66E-58 T 10-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 395 648 4.9E-61 T 10-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 SUPERFAMILY SSF51445 34 394 2.95E-98 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 273 290 - T 10-03-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 Gene3D G3DSA:3.40.50.1700 383 651 2.6E-80 T 10-03-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 120 139 5.3E-22 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 273 291 5.3E-22 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 5.3E-22 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 203 219 5.3E-22 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS24520 e68ffefc2094b23fdfa3dea8e02ec7ca 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 101 117 5.3E-22 T 10-03-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 SUPERFAMILY SSF103473 245 457 2.09E-58 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 SUPERFAMILY SSF103473 13 195 2.09E-58 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 Gene3D G3DSA:1.20.1250.20 261 459 2.2E-15 T 10-03-2017 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 433 4.3E-79 T 10-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 Gene3D G3DSA:1.20.1250.20 14 183 1.8E-25 T 10-03-2017 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 2.2E-9 T 10-03-2017 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 2.2E-9 T 10-03-2017 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 2.2E-9 T 10-03-2017 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 2.2E-9 T 10-03-2017 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 200 218 2.2E-9 T 10-03-2017 RG49_RS15440 8e167920944e158f7908af8ca01732bf 475 Pfam PF07690 Major Facilitator Superfamily 17 406 1.1E-45 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS10545 aaaff8be475c5d97c025671a412c037c 249 Gene3D G3DSA:3.90.1720.10 119 244 3.3E-41 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS10545 aaaff8be475c5d97c025671a412c037c 249 Pfam PF00877 NlpC/P60 family 131 241 9.2E-31 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS10545 aaaff8be475c5d97c025671a412c037c 249 SUPERFAMILY SSF54001 120 243 1.32E-36 T 10-03-2017 RG49_RS22860 c19304397ac23e2aa387684ae488c741 111 PIRSF PIRSF012296 1 111 2.9E-57 T 10-03-2017 IPR009307 Ethanolamine utilisation EutS GO:0006580 RG49_RS22860 c19304397ac23e2aa387684ae488c741 111 SUPERFAMILY SSF143414 39 107 2.62E-13 T 10-03-2017 RG49_RS22860 c19304397ac23e2aa387684ae488c741 111 Pfam PF00936 BMC domain 40 105 1.5E-12 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22860 c19304397ac23e2aa387684ae488c741 111 SMART SM00877 39 111 7.2E-14 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 Pfam PF02824 TGS domain 406 465 2.6E-21 T 10-03-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 Gene3D G3DSA:3.30.460.10 194 340 4.4E-50 T 10-03-2017 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 SMART SM00954 251 361 8.7E-66 T 10-03-2017 IPR007685 RelA/SpoT GO:0015969 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 SUPERFAMILY SSF81301 196 410 1.41E-63 T 10-03-2017 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 Pfam PF13328 HD domain 44 191 3.6E-40 T 10-03-2017 IPR003607 HD/PDEase domain RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 Pfam PF04607 Region found in RelA / SpoT proteins 251 360 1.8E-36 T 10-03-2017 IPR007685 RelA/SpoT GO:0015969 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 SUPERFAMILY SSF109604 27 207 3.77E-45 T 10-03-2017 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 Gene3D G3DSA:3.10.20.30 406 467 5.9E-26 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 Gene3D G3DSA:3.30.70.260 664 739 8.2E-29 T 10-03-2017 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 Pfam PF13291 ACT domain 664 740 6.7E-18 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 63 739 2.1E-186 T 10-03-2017 IPR004811 RelA/SpoT family GO:0015969 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 SUPERFAMILY SSF81271 399 465 5.07E-22 T 10-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 RG49_RS21130 49ff6fc65ed111112ee76be427a82132 744 SUPERFAMILY SSF55021 665 741 1.76E-14 T 10-03-2017 RG49_RS07665 cd37c86bc2968165e04b37190c24fbe5 181 Gene3D G3DSA:1.20.1380.10 68 181 5.3E-56 T 10-03-2017 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 RG49_RS07665 cd37c86bc2968165e04b37190c24fbe5 181 PIRSF PIRSF019401 1 181 1.3E-51 T 10-03-2017 IPR005621 Negative modulator of initiation of replicationr SeqA GO:0003677|GO:0032297 RG49_RS07665 cd37c86bc2968165e04b37190c24fbe5 181 Gene3D G3DSA:1.10.1220.10 1 40 5.6E-27 T 10-03-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 RG49_RS07665 cd37c86bc2968165e04b37190c24fbe5 181 SUPERFAMILY SSF82808 65 181 1.83E-50 T 10-03-2017 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 RG49_RS07665 cd37c86bc2968165e04b37190c24fbe5 181 Hamap MF_00908 Negative modulator of initiation of replication [seqA]. 1 181 47.033 T 10-03-2017 IPR005621 Negative modulator of initiation of replicationr SeqA GO:0003677|GO:0032297 RG49_RS07665 cd37c86bc2968165e04b37190c24fbe5 181 SUPERFAMILY SSF47598 1 35 4.45E-14 T 10-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 RG49_RS07665 cd37c86bc2968165e04b37190c24fbe5 181 Pfam PF03925 SeqA protein C-terminal domain 71 179 1.5E-50 T 10-03-2017 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 RG49_RS24165 8d77f686c066c4296f8b5f002af8963f 185 ProSitePatterns PS00194 Thioredoxin family active site. 72 90 - T 10-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 RG49_RS24165 8d77f686c066c4296f8b5f002af8963f 185 SUPERFAMILY SSF52833 46 178 3.94E-40 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS24165 8d77f686c066c4296f8b5f002af8963f 185 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 178 1.3E-85 T 10-03-2017 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 RG49_RS24165 8d77f686c066c4296f8b5f002af8963f 185 Pfam PF08534 Redoxin 42 166 5.2E-23 T 10-03-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 RG49_RS24165 8d77f686c066c4296f8b5f002af8963f 185 Gene3D G3DSA:3.40.30.10 10 178 5.3E-42 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08600 cacb2a3c455890e713cdc700f6ed12ea 208 Gene3D G3DSA:3.40.50.1110 29 205 2.0E-56 T 10-03-2017 IPR013830 SGNH hydrolase-type esterase domain RG49_RS08600 cacb2a3c455890e713cdc700f6ed12ea 208 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 30 40 - T 10-03-2017 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 RG49_RS08600 cacb2a3c455890e713cdc700f6ed12ea 208 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 33 187 7.3E-26 T 10-03-2017 IPR013830 SGNH hydrolase-type esterase domain RG49_RS08600 cacb2a3c455890e713cdc700f6ed12ea 208 SUPERFAMILY SSF52266 29 204 2.82E-52 T 10-03-2017 IPR013830 SGNH hydrolase-type esterase domain RG49_RS03985 31d267a4e80d9caed27ae117032c4ea9 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 282 9.5E-24 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03985 31d267a4e80d9caed27ae117032c4ea9 293 SUPERFAMILY SSF161098 58 282 3.53E-57 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03985 31d267a4e80d9caed27ae117032c4ea9 293 Gene3D G3DSA:1.10.3720.10 12 284 6.9E-60 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 SMART SM00869 691 945 1.4E-33 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 SUPERFAMILY SSF103515 667 955 3.92E-36 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 Gene3D G3DSA:2.40.128.130 626 955 4.5E-89 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 Gene3D G3DSA:2.160.20.20 46 625 4.2E-60 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 Pfam PF03212 Pertactin 494 615 3.1E-39 T 10-03-2017 IPR004899 Pertactin, central region RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 513 955 4.9E-108 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 SUPERFAMILY SSF51126 54 616 1.29E-30 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 PRINTS PR01484 Pertactin virulence factor family signature 826 843 7.2E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 PRINTS PR01484 Pertactin virulence factor family signature 911 936 7.2E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 PRINTS PR01484 Pertactin virulence factor family signature 873 894 7.2E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 PRINTS PR01484 Pertactin virulence factor family signature 671 689 7.2E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS04640 7c8ca88fee54e0e11ac2cc2784219ff2 955 Pfam PF03797 Autotransporter beta-domain 689 939 5.9E-41 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 Pfam PF01676 Metalloenzyme superfamily 6 500 1.9E-84 T 10-03-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 86 299 2.7E-83 T 10-03-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 Gene3D G3DSA:3.40.720.10 5 79 8.1E-89 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 Gene3D G3DSA:3.40.720.10 315 510 8.1E-89 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 PIRSF PIRSF001492 1 514 4.5E-206 T 10-03-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 Gene3D G3DSA:3.40.1450.10 80 310 8.8E-99 T 10-03-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 6 512 49.882 T 10-03-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 SUPERFAMILY SSF64158 79 310 1.09E-85 T 10-03-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 511 1.4E-246 T 10-03-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 SUPERFAMILY SSF53649 311 510 1.83E-74 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS16340 18d9078823e96bd4617edbb417129a72 514 SUPERFAMILY SSF53649 5 79 1.83E-74 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 SUPERFAMILY SSF46785 488 546 6.19E-7 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Pfam PF00009 Elongation factor Tu GTP binding domain 2 163 2.0E-31 T 10-03-2017 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 SUPERFAMILY SSF50447 175 293 1.96E-25 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Gene3D G3DSA:1.10.10.10 548 607 4.0E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 SUPERFAMILY SSF46785 417 484 1.36E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 607 5.7E-276 T 10-03-2017 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 SUPERFAMILY SSF50465 272 351 2.48E-7 T 10-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Pfam PF03144 Elongation factor Tu domain 2 189 256 7.8E-9 T 10-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Gene3D G3DSA:1.10.10.10 416 481 2.8E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 PRINTS PR00315 GTP-binding elongation factor signature 54 64 1.3E-7 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 PRINTS PR00315 GTP-binding elongation factor signature 2 15 1.3E-7 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 PRINTS PR00315 GTP-binding elongation factor signature 70 81 1.3E-7 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 PRINTS PR00315 GTP-binding elongation factor signature 107 116 1.3E-7 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Gene3D G3DSA:3.40.50.300 3 163 8.3E-42 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Pfam PF09106 Elongation factor SelB, winged helix 424 480 2.6E-15 T 10-03-2017 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Pfam PF09107 Elongation factor SelB, winged helix 560 605 3.1E-19 T 10-03-2017 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 SUPERFAMILY SSF52540 2 165 2.21E-41 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 Gene3D G3DSA:2.40.30.10 173 296 1.3E-27 T 10-03-2017 RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 SUPERFAMILY SSF46785 551 607 1.88E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16510 abb67769be6b7a885eef4718bb68acae 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 26 41 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 6 486 5.4E-228 T 10-03-2017 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 Pfam PF13091 PLD-like domain 332 446 2.2E-22 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 Pfam PF13091 PLD-like domain 134 248 1.6E-11 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 SUPERFAMILY SSF56024 66 315 4.08E-45 T 10-03-2017 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 Pfam PF13396 Phospholipase_D-nuclease N-terminal 23 59 2.2E-6 T 10-03-2017 IPR027379 Cardiolipin synthase N-terminal RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 Gene3D G3DSA:3.30.870.10 111 316 2.9E-33 T 10-03-2017 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 SMART SM00155 399 426 8.2E-6 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 SMART SM00155 219 246 2.1E-4 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 SUPERFAMILY SSF56024 273 473 9.42E-48 T 10-03-2017 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 Gene3D G3DSA:3.30.870.10 317 460 3.8E-35 T 10-03-2017 RG49_RS04350 6697711c6e912f9ee4c02921c93f6914 486 Hamap MF_00190 Cardiolipin synthase A [clsA]. 2 486 51.264 T 10-03-2017 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 RG49_RS10735 fcad8829648bb092cee519c4330dc9b5 155 Gene3D G3DSA:3.30.420.10 3 148 2.8E-62 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10735 fcad8829648bb092cee519c4330dc9b5 155 Pfam PF00075 RNase H 3 141 1.1E-54 T 10-03-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 RG49_RS10735 fcad8829648bb092cee519c4330dc9b5 155 SUPERFAMILY SSF53098 4 147 7.71E-59 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10735 fcad8829648bb092cee519c4330dc9b5 155 Hamap MF_00042 Ribonuclease H [rnhA]. 2 149 40.321 T 10-03-2017 IPR022892 Ribonuclease H GO:0004523 RG49_RS11990 56be9aa27d473e69428813b2550e4edd 87 Pfam PF01381 Helix-turn-helix 23 76 2.2E-6 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS11990 56be9aa27d473e69428813b2550e4edd 87 Gene3D G3DSA:1.10.260.40 23 79 5.2E-9 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS11990 56be9aa27d473e69428813b2550e4edd 87 SUPERFAMILY SSF47413 17 79 5.63E-9 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS11990 56be9aa27d473e69428813b2550e4edd 87 SMART SM00530 22 76 1.1E-6 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 Gene3D G3DSA:3.40.50.1980 198 308 2.2E-31 T 10-03-2017 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 Gene3D G3DSA:3.40.50.1980 16 197 9.7E-45 T 10-03-2017 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 PRINTS PR00690 Adhesin family signature 249 267 4.4E-8 T 10-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 PRINTS PR00690 Adhesin family signature 69 86 4.4E-8 T 10-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 PRINTS PR00690 Adhesin family signature 56 69 4.4E-8 T 10-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 PRINTS PR00690 Adhesin family signature 196 217 4.4E-8 T 10-03-2017 IPR006128 Adhesion lipoprotein GO:0007155 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 SUPERFAMILY SSF53807 27 308 4.17E-74 T 10-03-2017 RG49_RS00635 232274a276b8cbc770514bc4cf73c20f 310 Pfam PF01297 Zinc-uptake complex component A periplasmic 28 306 1.6E-57 T 10-03-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 RG49_RS24700 959a5629eecad28b9fd7ba2971ef581b 350 SMART SM01133 68 326 5.5E-42 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS24700 959a5629eecad28b9fd7ba2971ef581b 350 SUPERFAMILY SSF51569 56 242 5.13E-66 T 10-03-2017 RG49_RS24700 959a5629eecad28b9fd7ba2971ef581b 350 SUPERFAMILY SSF51569 270 344 5.13E-66 T 10-03-2017 RG49_RS24700 959a5629eecad28b9fd7ba2971ef581b 350 Gene3D G3DSA:3.20.20.70 52 346 4.2E-101 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS24700 959a5629eecad28b9fd7ba2971ef581b 350 Pfam PF01791 DeoC/LacD family aldolase 69 326 4.0E-75 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 8 1172 0.0 T 10-03-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Pfam PF12705 PD-(D/E)XK nuclease superfamily 950 1150 9.4E-6 T 10-03-2017 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:1.10.486.10 583 728 9.2E-58 T 10-03-2017 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:3.90.320.10 890 1177 2.7E-108 T 10-03-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:1.10.3170.10 155 349 2.3E-72 T 10-03-2017 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 SUPERFAMILY SSF52980 899 1174 5.36E-96 T 10-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 6 1173 23.209 T 10-03-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Pfam PF13361 UvrD-like helicase C-terminal domain 681 808 2.5E-11 T 10-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:3.40.50.300 729 882 3.3E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:3.40.50.300 450 580 3.3E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 437 2.3E-70 T 10-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:3.40.50.300 14 82 6.9E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:3.40.50.300 351 449 6.9E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 Gene3D G3DSA:3.40.50.300 120 150 6.9E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 SUPERFAMILY SSF52540 325 825 9.65E-108 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 SUPERFAMILY SSF52540 14 80 9.65E-108 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20940 0056f083a72f8d0989b4e00704f0bfa9 1180 SUPERFAMILY SSF52540 118 202 9.65E-108 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20955 b0ce837712b6fcb3ce6fe669e1631481 447 Gene3D G3DSA:3.40.630.40 218 315 8.4E-60 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS20955 b0ce837712b6fcb3ce6fe669e1631481 447 Gene3D G3DSA:3.40.630.40 362 437 8.4E-60 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS20955 b0ce837712b6fcb3ce6fe669e1631481 447 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 220 434 1.4E-50 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS20955 b0ce837712b6fcb3ce6fe669e1631481 447 SMART SM00646 280 434 3.8E-68 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS20955 b0ce837712b6fcb3ce6fe669e1631481 447 Pfam PF11741 AMIN domain 69 172 1.2E-26 T 10-03-2017 IPR021731 AMIN domain RG49_RS20955 b0ce837712b6fcb3ce6fe669e1631481 447 SUPERFAMILY SSF53187 218 314 1.16E-52 T 10-03-2017 RG49_RS20955 b0ce837712b6fcb3ce6fe669e1631481 447 SUPERFAMILY SSF53187 361 437 1.16E-52 T 10-03-2017 RG49_RS00730 8551881d7a6c38932fa38acb68286fd2 218 Pfam PF00795 Carbon-nitrogen hydrolase 5 113 1.8E-16 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS00730 8551881d7a6c38932fa38acb68286fd2 218 SUPERFAMILY SSF56317 4 196 8.24E-19 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS00730 8551881d7a6c38932fa38acb68286fd2 218 Gene3D G3DSA:3.60.110.10 3 113 1.5E-11 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Gene3D G3DSA:1.10.10.10 671 769 7.6E-43 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Gene3D G3DSA:3.40.1360.10 206 311 2.4E-7 T 10-03-2017 RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Pfam PF13362 Toprim domain 210 299 2.0E-11 T 10-03-2017 IPR006171 Toprim domain RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 SUPERFAMILY SSF46785 671 769 2.34E-38 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 SUPERFAMILY SSF52540 431 623 7.17E-18 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 SMART SM00778 30 66 6.6E-21 T 10-03-2017 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Pfam PF08273 Zinc-binding domain of primase-helicase 30 66 4.6E-18 T 10-03-2017 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Pfam PF03288 Poxvirus D5 protein-like 670 769 2.5E-21 T 10-03-2017 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 SMART SM00493 208 283 1.7E-7 T 10-03-2017 IPR006171 Toprim domain RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Gene3D G3DSA:3.90.580.10 29 89 4.0E-6 T 10-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Gene3D G3DSA:3.40.50.300 472 646 8.6E-19 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 SUPERFAMILY SSF57783 16 93 2.21E-10 T 10-03-2017 RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 Pfam PF08706 D5 N terminal like 336 467 1.3E-10 T 10-03-2017 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal RG49_RS21870 f539891ad0d1354c1262a1f22137f433 777 SMART SM00885 336 463 3.2E-25 T 10-03-2017 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal RG49_RS05865 261ee94e79757dc5d341bc860914cd1a 109 PIRSF PIRSF006223 2 109 2.8E-47 T 10-03-2017 IPR007453 Sulphur transfer protein DsrC/TusE RG49_RS05865 261ee94e79757dc5d341bc860914cd1a 109 SUPERFAMILY SSF69721 2 109 4.97E-42 T 10-03-2017 IPR025526 DsrC-like domain RG49_RS05865 261ee94e79757dc5d341bc860914cd1a 109 Gene3D G3DSA:1.10.10.370 40 109 1.8E-38 T 10-03-2017 RG49_RS05865 261ee94e79757dc5d341bc860914cd1a 109 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 109 6.3E-50 T 10-03-2017 IPR007453 Sulphur transfer protein DsrC/TusE RG49_RS05865 261ee94e79757dc5d341bc860914cd1a 109 Pfam PF04358 DsrC like protein 4 109 9.4E-46 T 10-03-2017 IPR007453 Sulphur transfer protein DsrC/TusE RG49_RS05865 261ee94e79757dc5d341bc860914cd1a 109 Gene3D G3DSA:3.30.1420.10 1 39 1.4E-12 T 10-03-2017 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 Gene3D G3DSA:3.40.50.2300 6 134 4.7E-42 T 10-03-2017 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 SUPERFAMILY SSF52172 6 190 7.68E-50 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 SUPERFAMILY SSF46689 358 457 1.97E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 Gene3D G3DSA:3.40.50.300 144 317 3.7E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 Pfam PF00158 Sigma-54 interaction domain 146 311 9.7E-73 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 SMART SM00382 165 308 7.4E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 Pfam PF00072 Response regulator receiver domain 7 115 2.0E-30 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 457 1.4E-11 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 437 1.4E-11 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 SMART SM00448 5 116 4.1E-42 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 Gene3D G3DSA:1.10.8.60 318 390 3.3E-26 T 10-03-2017 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 Gene3D G3DSA:1.10.10.60 391 457 3.5E-18 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 SUPERFAMILY SSF52540 145 388 1.68E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS24010 760acb13aeaa93b4aeae34115bdd632d 461 Pfam PF02954 Bacterial regulatory protein, Fis family 415 454 4.7E-14 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 Gene3D G3DSA:2.40.50.40 136 205 8.8E-26 T 10-03-2017 RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 SUPERFAMILY SSF52172 2 162 2.13E-26 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 SMART SM00850 145 243 3.2E-39 T 10-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 Gene3D G3DSA:2.20.25.10 206 244 5.2E-14 T 10-03-2017 RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 Gene3D G3DSA:3.40.50.2300 2 126 9.1E-30 T 10-03-2017 RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 Pfam PF04397 LytTr DNA-binding domain 146 242 2.3E-33 T 10-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 SMART SM00448 1 112 1.4E-19 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS23235 f90eb5313ad6c83397045c57afb8d33f 244 Pfam PF00072 Response regulator receiver domain 3 112 1.6E-23 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 Pfam PF00999 Sodium/hydrogen exchanger family 11 374 1.6E-61 T 10-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 285 1.1E-94 T 10-03-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 PRINTS PR00335 TrkA potassium uptake protein signature 458 468 2.0E-8 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 PRINTS PR00335 TrkA potassium uptake protein signature 418 432 2.0E-8 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 PRINTS PR00335 TrkA potassium uptake protein signature 401 415 2.0E-8 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 PRINTS PR00335 TrkA potassium uptake protein signature 447 457 2.0E-8 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 Gene3D G3DSA:3.40.50.720 395 530 2.4E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 Hamap MF_01413 Glutathione-regulated potassium-efflux system protein KefC [kefC]. 1 607 55.313 T 10-03-2017 IPR023941 Glutathione-regulated potassium-efflux system protein KefC GO:0005887|GO:0006813|GO:0015503|GO:0015643|GO:0019899|GO:0051595 RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 SUPERFAMILY SSF51735 401 530 1.05E-33 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11630 05e52805c257ab46aedd76f2937d2a46 620 Pfam PF02254 TrkA-N domain 402 512 3.5E-26 T 10-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 SMART SM00052 408 653 2.7E-115 T 10-03-2017 IPR001633 EAL domain RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 Gene3D G3DSA:3.20.20.450 413 657 1.7E-76 T 10-03-2017 IPR001633 EAL domain RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 Pfam PF00672 HAMP domain 162 232 2.0E-12 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 SUPERFAMILY SSF55073 248 400 1.65E-17 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 Pfam PF17154 Gammaproteobacterial periplasmic sensor domain 36 155 1.1E-50 T 10-03-2017 IPR033419 Gammaproteobacterial periplasmic sensor domain GAPES3 RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 SMART SM00267 231 398 1.5E-40 T 10-03-2017 IPR000160 GGDEF domain RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 Pfam PF00990 Diguanylate cyclase, GGDEF domain 247 394 2.6E-11 T 10-03-2017 IPR000160 GGDEF domain RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 SUPERFAMILY SSF141868 413 658 6.28E-73 T 10-03-2017 IPR001633 EAL domain RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 Gene3D G3DSA:3.30.70.270 247 404 6.0E-17 T 10-03-2017 RG49_RS16870 2be63e6cc3bd22e3344a8978940a9a24 662 Pfam PF00563 EAL domain 415 648 3.3E-60 T 10-03-2017 IPR001633 EAL domain RG49_RS06855 15e6565cfd76f124386d3ae2744c50dd 512 Gene3D G3DSA:3.10.105.10 281 481 6.6E-61 T 10-03-2017 RG49_RS06855 15e6565cfd76f124386d3ae2744c50dd 512 Gene3D G3DSA:3.40.190.10 130 280 1.2E-50 T 10-03-2017 RG49_RS06855 15e6565cfd76f124386d3ae2744c50dd 512 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 76 98 - T 10-03-2017 IPR023765 Solute-binding protein family 5, conserved site RG49_RS06855 15e6565cfd76f124386d3ae2744c50dd 512 PIRSF PIRSF002741 24 511 2.2E-107 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS06855 15e6565cfd76f124386d3ae2744c50dd 512 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 429 8.2E-97 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS06855 15e6565cfd76f124386d3ae2744c50dd 512 SUPERFAMILY SSF53850 30 510 2.07E-144 T 10-03-2017 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 SUPERFAMILY SSF53335 5 267 5.15E-78 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 10 251 1.6E-75 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 TIGRFAM TIGR00571 dam: DNA adenine methylase 5 267 4.8E-106 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 Gene3D G3DSA:1.10.1020.10 60 157 1.5E-34 T 10-03-2017 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 Gene3D G3DSA:3.40.50.150 1 59 2.1E-54 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 Gene3D G3DSA:3.40.50.150 160 267 2.1E-54 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 10 26 4.2E-19 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 175 187 4.2E-19 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 31 45 4.2E-19 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 50 63 4.2E-19 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS17650 847c46aedb463dd8c17909b174c161cf 278 PIRSF PIRSF000398 1 272 3.5E-68 T 10-03-2017 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 SMART SM01232 129 221 3.8E-50 T 10-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 1.4E-108 T 10-03-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 244 268 - T 10-03-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 SUPERFAMILY SSF81624 2 138 1.15E-44 T 10-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 Gene3D G3DSA:1.10.8.50 130 269 7.5E-52 T 10-03-2017 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.8E-32 T 10-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 129 218 1.1E-31 T 10-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 SMART SM00898 2 115 2.8E-55 T 10-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 Gene3D G3DSA:3.20.190.10 2 129 1.4E-38 T 10-03-2017 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 269 1.0E-9 T 10-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 SUPERFAMILY SSF46946 130 222 3.93E-31 T 10-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 269 44.679 T 10-03-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 RG49_RS16225 b2bfeb000b2a24507f3b227728727ebf 269 SUPERFAMILY SSF57716 217 269 2.85E-17 T 10-03-2017 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 688 27.272 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 SUPERFAMILY SSF109604 339 511 5.34E-17 T 10-03-2017 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 318 334 7.1E-37 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 7.1E-37 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 7.1E-37 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 246 261 7.1E-37 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 7.1E-37 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 551 8.2E-216 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 Gene3D G3DSA:1.10.730.10 582 678 1.4E-4 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 689 0.0 T 10-03-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16685 2edc2c6fef1d85dd7c17edb06208498b 689 Pfam PF05746 DALR anticodon binding domain 582 679 3.0E-8 T 10-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 RG49_RS12710 0aab4f261dd10dd94d988ff978da9e9b 154 Gene3D G3DSA:3.20.20.70 22 129 1.7E-8 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS12710 0aab4f261dd10dd94d988ff978da9e9b 154 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 10-03-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 RG49_RS12710 0aab4f261dd10dd94d988ff978da9e9b 154 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 153 1.3E-66 T 10-03-2017 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 RG49_RS12710 0aab4f261dd10dd94d988ff978da9e9b 154 SUPERFAMILY SSF102114 24 105 7.46E-7 T 10-03-2017 RG49_RS12710 0aab4f261dd10dd94d988ff978da9e9b 154 PIRSF PIRSF000368 1 154 1.7E-61 T 10-03-2017 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 RG49_RS12710 0aab4f261dd10dd94d988ff978da9e9b 154 Pfam PF13353 4Fe-4S single cluster domain 12 151 3.9E-53 T 10-03-2017 RG49_RS01480 ea4b04bdc62b56c09e81cdb9ca63bfd8 154 Gene3D G3DSA:3.90.1720.10 38 154 4.1E-40 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS01480 ea4b04bdc62b56c09e81cdb9ca63bfd8 154 Pfam PF00877 NlpC/P60 family 47 153 5.7E-31 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS01480 ea4b04bdc62b56c09e81cdb9ca63bfd8 154 SUPERFAMILY SSF54001 34 154 3.07E-39 T 10-03-2017 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Pfam PF00270 DEAD/DEAH box helicase 602 762 7.5E-21 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Pfam PF00271 Helicase conserved C-terminal domain 803 906 1.7E-18 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SUPERFAMILY SSF141259 467 545 1.57E-23 T 10-03-2017 IPR003711 CarD-like/TRCF domain RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SUPERFAMILY SSF52540 520 780 1.67E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Gene3D G3DSA:3.30.2060.10 130 207 1.8E-13 T 10-03-2017 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SMART SM00982 1005 1105 1.9E-49 T 10-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Pfam PF02559 CarD-like/TRCF domain 477 572 2.3E-24 T 10-03-2017 IPR003711 CarD-like/TRCF domain RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SUPERFAMILY SSF52540 779 987 3.01E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Pfam PF03461 TRCF domain 1006 1098 2.4E-28 T 10-03-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 145 1079 0.0 T 10-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SMART SM01058 476 573 3.1E-50 T 10-03-2017 IPR003711 CarD-like/TRCF domain RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Gene3D G3DSA:3.40.50.300 585 783 2.0E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SMART SM00490 823 907 1.6E-19 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SUPERFAMILY SSF143517 992 1144 1.57E-44 T 10-03-2017 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 31 1125 28.923 T 10-03-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 Gene3D G3DSA:3.40.50.300 795 960 3.4E-36 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SUPERFAMILY SSF52540 10 343 1.59E-100 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SUPERFAMILY SSF52540 351 463 1.25E-27 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05065 96fea58ba2ef4705cd435180e0c05fe7 1148 SMART SM00487 597 787 6.4E-36 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS14365 3d42d701123a2473ba8f8fbf36f3afeb 765 SUPERFAMILY SSF51998 1 764 2.62E-222 T 10-03-2017 RG49_RS14365 3d42d701123a2473ba8f8fbf36f3afeb 765 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 1 765 0.0 T 10-03-2017 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 RG49_RS14365 3d42d701123a2473ba8f8fbf36f3afeb 765 ProSitePatterns PS00850 Glycine radical domain signature. 736 744 - T 10-03-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site RG49_RS14365 3d42d701123a2473ba8f8fbf36f3afeb 765 Gene3D G3DSA:3.20.70.20 1 764 2.2E-257 T 10-03-2017 RG49_RS14365 3d42d701123a2473ba8f8fbf36f3afeb 765 Pfam PF02901 Pyruvate formate lyase-like 1 626 1.3E-203 T 10-03-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 RG49_RS14365 3d42d701123a2473ba8f8fbf36f3afeb 765 Pfam PF01228 Glycine radical 646 747 2.9E-27 T 10-03-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 RG49_RS02895 c2ca9940392015bff489ca1213c49a3c 516 Gene3D G3DSA:3.40.190.10 137 287 2.1E-48 T 10-03-2017 RG49_RS02895 c2ca9940392015bff489ca1213c49a3c 516 PIRSF PIRSF002741 11 516 1.9E-110 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS02895 c2ca9940392015bff489ca1213c49a3c 516 Gene3D G3DSA:3.10.105.10 288 485 4.4E-56 T 10-03-2017 RG49_RS02895 c2ca9940392015bff489ca1213c49a3c 516 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 83 105 - T 10-03-2017 IPR023765 Solute-binding protein family 5, conserved site RG49_RS02895 c2ca9940392015bff489ca1213c49a3c 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 432 2.7E-94 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS02895 c2ca9940392015bff489ca1213c49a3c 516 SUPERFAMILY SSF53850 30 509 5.65E-134 T 10-03-2017 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 SUPERFAMILY SSF56655 1 261 2.36E-86 T 10-03-2017 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 10-03-2017 IPR020583 Inositol monophosphatase, metal-binding site RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 10-03-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 Pfam PF00459 Inositol monophosphatase family 2 259 1.4E-74 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 Gene3D G3DSA:3.40.190.80 153 259 9.7E-39 T 10-03-2017 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 1.6E-62 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 1.6E-62 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.6E-62 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.6E-62 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 1.6E-62 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.6E-62 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 Gene3D G3DSA:3.30.540.10 2 152 7.1E-54 T 10-03-2017 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 1.0E-36 T 10-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 1.0E-36 T 10-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 1.0E-36 T 10-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 RG49_RS22405 ccdb8a845e15184007f49a2366f7bc56 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 1.0E-36 T 10-03-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 RG49_RS14630 399461df94e717055d166077233fe3f4 489 Gene3D G3DSA:3.30.420.40 6 242 2.8E-29 T 10-03-2017 RG49_RS14630 399461df94e717055d166077233fe3f4 489 SUPERFAMILY SSF53067 7 245 7.77E-49 T 10-03-2017 RG49_RS14630 399461df94e717055d166077233fe3f4 489 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 253 439 2.1E-25 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS14630 399461df94e717055d166077233fe3f4 489 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 243 5.3E-29 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS14630 399461df94e717055d166077233fe3f4 489 SUPERFAMILY SSF53067 252 471 3.63E-31 T 10-03-2017 RG49_RS14630 399461df94e717055d166077233fe3f4 489 Gene3D G3DSA:3.30.420.40 363 473 6.1E-15 T 10-03-2017 RG49_RS14630 399461df94e717055d166077233fe3f4 489 Hamap MF_01535 Rhamnulokinase [rhaB]. 6 483 54.353 T 10-03-2017 IPR013449 Rhamnulokinase GO:0008993|GO:0019301 KEGG: 00040+2.7.1.5|KEGG: 00051+2.7.1.5 RG49_RS14630 399461df94e717055d166077233fe3f4 489 TIGRFAM TIGR02627 rhamnulo_kin: rhamnulokinase 7 460 4.1E-243 T 10-03-2017 IPR013449 Rhamnulokinase GO:0008993|GO:0019301 KEGG: 00040+2.7.1.5|KEGG: 00051+2.7.1.5 RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 SUPERFAMILY SSF49503 172 310 1.29E-30 T 10-03-2017 IPR008972 Cupredoxin RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 Hamap MF_00915 Cell division protein FtsP [ftsP]. 1 467 58.919 T 10-03-2017 IPR026589 Cell division protein FtsP GO:0043093 RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 Pfam PF07731 Multicopper oxidase 359 468 5.4E-13 T 10-03-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 SUPERFAMILY SSF49503 3 165 7.37E-26 T 10-03-2017 IPR008972 Cupredoxin RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 Pfam PF07732 Multicopper oxidase 52 166 7.6E-27 T 10-03-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 SUPERFAMILY SSF49503 314 466 2.22E-18 T 10-03-2017 IPR008972 Cupredoxin RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 Gene3D G3DSA:2.60.40.420 172 288 3.1E-30 T 10-03-2017 IPR008972 Cupredoxin RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 Gene3D G3DSA:2.60.40.420 357 467 3.9E-12 T 10-03-2017 IPR008972 Cupredoxin RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 Gene3D G3DSA:2.60.40.420 32 171 1.2E-21 T 10-03-2017 IPR008972 Cupredoxin RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 0.0015 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS19670 b1cbeba5d0a5c242fd072b71b7f6541a 470 Pfam PF00394 Multicopper oxidase 223 287 3.5E-4 T 10-03-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 RG49_RS05295 3ef9c0c48a0d3fc5b259b914cd6bf04d 138 Pfam PF05130 FlgN protein 1 128 1.0E-18 T 10-03-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 RG49_RS05295 3ef9c0c48a0d3fc5b259b914cd6bf04d 138 SUPERFAMILY SSF140566 1 111 9.02E-16 T 10-03-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 RG49_RS05295 3ef9c0c48a0d3fc5b259b914cd6bf04d 138 Gene3D G3DSA:1.20.58.300 1 112 3.9E-10 T 10-03-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 Gene3D G3DSA:3.40.50.2300 9 156 5.9E-39 T 10-03-2017 RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 1.6E-23 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 Gene3D G3DSA:1.10.10.10 157 235 3.5E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 Pfam PF00072 Response regulator receiver domain 13 121 1.1E-24 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 SMART SM00862 156 232 2.2E-25 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 SUPERFAMILY SSF46894 142 234 3.97E-26 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 SMART SM00448 11 121 6.2E-39 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24780 2a7a296687bb30a43a16c69021e7bb87 240 SUPERFAMILY SSF52172 6 138 9.96E-40 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS15910 5005d6db5bf8024bec200c0277610d11 500 Gene3D G3DSA:3.30.565.10 373 496 1.4E-8 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15910 5005d6db5bf8024bec200c0277610d11 500 SMART SM00387 409 499 7.0E-12 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15910 5005d6db5bf8024bec200c0277610d11 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 412 497 1.8E-6 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15910 5005d6db5bf8024bec200c0277610d11 500 Pfam PF05231 MASE1 12 276 7.2E-14 T 10-03-2017 IPR007895 MASE1 RG49_RS15910 5005d6db5bf8024bec200c0277610d11 500 SUPERFAMILY SSF55874 385 496 2.19E-17 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15910 5005d6db5bf8024bec200c0277610d11 500 Pfam PF07730 Histidine kinase 305 370 1.4E-14 T 10-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 RG49_RS08895 691aaa4d560b5b382c886b4b7167d284 566 SUPERFAMILY SSF53850 115 561 2.71E-57 T 10-03-2017 RG49_RS08895 691aaa4d560b5b382c886b4b7167d284 566 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 165 303 1.4E-15 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS08895 691aaa4d560b5b382c886b4b7167d284 566 Gene3D G3DSA:3.90.76.10 133 274 1.2E-20 T 10-03-2017 RG49_RS08895 691aaa4d560b5b382c886b4b7167d284 566 Pfam PF12793 Sugar transport-related sRNA regulator N-term 6 118 3.0E-39 T 10-03-2017 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain RG49_RS08895 691aaa4d560b5b382c886b4b7167d284 566 Gene3D G3DSA:3.10.105.10 405 533 5.8E-5 T 10-03-2017 RG49_RS18105 1d39cb39316a9c2998ec292730c96ef2 38 Pfam PF00444 Ribosomal protein L36 1 38 2.2E-20 T 10-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18105 1d39cb39316a9c2998ec292730c96ef2 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 5.9E-22 T 10-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18105 1d39cb39316a9c2998ec292730c96ef2 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 17.829 T 10-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18105 1d39cb39316a9c2998ec292730c96ef2 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 3.0E-10 T 10-03-2017 RG49_RS18105 1d39cb39316a9c2998ec292730c96ef2 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 10-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18105 1d39cb39316a9c2998ec292730c96ef2 38 SUPERFAMILY SSF57840 1 38 5.89E-17 T 10-03-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 SMART SM00987 49 210 1.0E-41 T 10-03-2017 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 SMART SM00986 49 210 1.0E-41 T 10-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 Pfam PF03167 Uracil DNA glycosylase superfamily 55 209 2.1E-28 T 10-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 10-03-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 214 8.1E-91 T 10-03-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 4 221 40.502 T 10-03-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 Gene3D G3DSA:3.40.470.10 6 221 2.2E-102 T 10-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS22135 c54e4c0a24c178ca13e44a4881f22111 229 SUPERFAMILY SSF52141 6 220 5.67E-96 T 10-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS01405 5edc61b856f1abc20d3e9eec44ba1c39 471 SUPERFAMILY SSF48403 202 447 5.25E-9 T 10-03-2017 IPR020683 Ankyrin repeat-containing domain RG49_RS01405 5edc61b856f1abc20d3e9eec44ba1c39 471 Gene3D G3DSA:1.25.40.20 231 448 6.1E-8 T 10-03-2017 IPR020683 Ankyrin repeat-containing domain RG49_RS01405 5edc61b856f1abc20d3e9eec44ba1c39 471 Pfam PF07906 ShET2 enterotoxin, N-terminal region 2 235 2.9E-88 T 10-03-2017 IPR012927 ShET2 enterotoxin, N-terminal RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 SUPERFAMILY SSF52540 3 269 4.18E-122 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 SUPERFAMILY SSF52317 289 542 2.06E-88 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 Gene3D G3DSA:3.40.50.300 1 280 4.1E-134 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 Gene3D G3DSA:3.40.50.880 288 541 1.7E-97 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 Pfam PF00117 Glutamine amidotransferase class-I 301 535 2.8E-65 T 10-03-2017 IPR017926 Glutamine amidotransferase RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 1.6E-266 T 10-03-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 Pfam PF06418 CTP synthase N-terminus 5 266 5.0E-126 T 10-03-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 RG49_RS21150 65fa8534717f4498012197a9bedf951b 545 Hamap MF_01227 CTP synthase [pyrG]. 3 540 50.971 T 10-03-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 RG49_RS09570 d5e9df17435c9722b3defcb84f0bce59 283 SMART SM00052 26 272 6.1E-114 T 10-03-2017 IPR001633 EAL domain RG49_RS09570 d5e9df17435c9722b3defcb84f0bce59 283 SUPERFAMILY SSF141868 33 275 1.31E-71 T 10-03-2017 IPR001633 EAL domain RG49_RS09570 d5e9df17435c9722b3defcb84f0bce59 283 Gene3D G3DSA:3.20.20.450 33 274 1.9E-72 T 10-03-2017 IPR001633 EAL domain RG49_RS09570 d5e9df17435c9722b3defcb84f0bce59 283 Pfam PF00563 EAL domain 33 267 6.3E-61 T 10-03-2017 IPR001633 EAL domain RG49_RS12715 839199d107d2e8162971431972d49187 128 Gene3D G3DSA:1.20.120.10 23 128 1.2E-45 T 10-03-2017 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 RG49_RS12715 839199d107d2e8162971431972d49187 128 PIRSF PIRSF000029 1 128 1.3E-63 T 10-03-2017 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 RG49_RS12715 839199d107d2e8162971431972d49187 128 SUPERFAMILY SSF47175 23 128 3.4E-35 T 10-03-2017 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 RG49_RS12715 839199d107d2e8162971431972d49187 128 Pfam PF07361 Cytochrome b562 24 128 1.1E-31 T 10-03-2017 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 SMART SM00382 365 549 3.5E-16 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 SUPERFAMILY SSF52540 333 569 7.42E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 SUPERFAMILY SSF90123 7 327 3.27E-42 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 Gene3D G3DSA:3.40.50.300 339 568 2.0E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 Pfam PF00005 ABC transporter 356 502 4.2E-34 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 Pfam PF00664 ABC transporter transmembrane region 58 287 1.4E-10 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 6 533 8.2E-182 T 10-03-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 RG49_RS06310 96a1156b9cb343a5b689b5321509e9a8 573 Gene3D G3DSA:1.20.1560.10 8 327 9.7E-31 T 10-03-2017 RG49_RS05255 d5bb5ca9c52fff494b56f4dc20ba61ee 260 Pfam PF00460 Flagella basal body rod protein 5 35 8.6E-14 T 10-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 RG49_RS05255 d5bb5ca9c52fff494b56f4dc20ba61ee 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 260 1.2E-26 T 10-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain RG49_RS05255 d5bb5ca9c52fff494b56f4dc20ba61ee 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 10-03-2017 IPR019776 Flagellar basal body rod protein, conserved site RG49_RS05255 d5bb5ca9c52fff494b56f4dc20ba61ee 260 SUPERFAMILY SSF117143 93 222 9.94E-35 T 10-03-2017 RG49_RS05255 d5bb5ca9c52fff494b56f4dc20ba61ee 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 145 243 2.4E-29 T 10-03-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G RG49_RS05255 d5bb5ca9c52fff494b56f4dc20ba61ee 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 9.5E-49 T 10-03-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G RG49_RS05255 d5bb5ca9c52fff494b56f4dc20ba61ee 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 4.5E-117 T 10-03-2017 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 RG49_RS23690 dadb23aca088493e208ad39c45dda147 184 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 17 157 3.0E-33 T 10-03-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02145 aac39d8f849e8d030cb4c1dc3a9352dc 101 ProDom PD336997 PRECURSOR SIGNAL MEMBRANE OUTER YNFD ESCHERICHIA EXPORTED PP0087 COLI PP0090 1 79 1.0E-31 T 10-03-2017 IPR010595 Protein of unknown function DUF1161 RG49_RS02145 aac39d8f849e8d030cb4c1dc3a9352dc 101 Pfam PF06649 Protein of unknown function (DUF1161) 26 79 3.2E-22 T 10-03-2017 IPR010595 Protein of unknown function DUF1161 RG49_RS10505 ea312b6c6d9c1138ed3a5a72589cf48b 150 Gene3D G3DSA:3.40.630.30 1 147 1.5E-35 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS10505 ea312b6c6d9c1138ed3a5a72589cf48b 150 Pfam PF13673 Acetyltransferase (GNAT) domain 31 141 2.1E-19 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS10505 ea312b6c6d9c1138ed3a5a72589cf48b 150 SUPERFAMILY SSF55729 1 146 9.75E-28 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 104.67 T 10-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 TIGRFAM TIGR00615 recR: recombination protein RecR 2 197 3.9E-85 T 10-03-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 SMART SM00493 81 166 2.1E-20 T 10-03-2017 IPR006171 Toprim domain RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 10-03-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 SUPERFAMILY SSF111304 2 199 7.98E-73 T 10-03-2017 IPR023627 Recombination protein RecR RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 Pfam PF13662 Toprim domain 82 172 1.7E-24 T 10-03-2017 IPR006171 Toprim domain RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 Gene3D G3DSA:3.40.50.140 135 171 0.001 T 10-03-2017 IPR006171 Toprim domain RG49_RS08735 90556cceaea882a61285fd22312b2d34 201 Pfam PF02132 RecR protein 41 77 2.0E-15 T 10-03-2017 IPR023628 Recombination protein RecR, C4-type zinc finger RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 7.3E-45 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 7.3E-45 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 7.3E-45 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 7.3E-45 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 7.3E-45 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 SUPERFAMILY SSF53098 3 156 1.87E-56 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 6.1E-69 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 10-03-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 Gene3D G3DSA:3.30.420.10 3 157 1.3E-67 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 46.69 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS00600 539598d2fa64fa2ffaa2e499b33e63ab 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 159 2.8E-88 T 10-03-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 RG49_RS24385 92a43109126430852293811a8156119c 663 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 152 5.9E-33 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS24385 92a43109126430852293811a8156119c 663 Pfam PF00593 TonB dependent receptor 395 662 1.4E-39 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS24385 92a43109126430852293811a8156119c 663 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 646 663 - T 10-03-2017 IPR010917 TonB-dependent receptor, conserved site RG49_RS24385 92a43109126430852293811a8156119c 663 Gene3D G3DSA:2.170.130.10 41 157 2.3E-45 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS24385 92a43109126430852293811a8156119c 663 Gene3D G3DSA:2.40.170.20 158 663 5.3E-116 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS24385 92a43109126430852293811a8156119c 663 SUPERFAMILY SSF56935 29 663 3.14E-129 T 10-03-2017 RG49_RS24385 92a43109126430852293811a8156119c 663 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 38 - T 10-03-2017 IPR010916 TonB box, conserved site RG49_RS06455 871e57acd61164ecb3799e3d96dfe186 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 5 110 2.8E-17 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS06455 871e57acd61164ecb3799e3d96dfe186 222 Gene3D G3DSA:1.10.3720.10 4 214 3.8E-35 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06455 871e57acd61164ecb3799e3d96dfe186 222 SUPERFAMILY SSF161098 6 201 1.57E-28 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06455 871e57acd61164ecb3799e3d96dfe186 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 214 1.8E-11 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 ProSitePatterns PS00517 Ribonuclease III family signature. 38 46 - T 10-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 SMART SM00358 156 224 9.1E-24 T 10-03-2017 IPR014720 Double-stranded RNA-binding domain RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 Gene3D G3DSA:3.30.160.20 153 223 8.7E-29 T 10-03-2017 IPR014720 Double-stranded RNA-binding domain RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 Hamap MF_00104 Ribonuclease 3 [rnc]. 9 220 29.49 T 10-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 Pfam PF14622 Ribonuclease-III-like 20 141 1.6E-33 T 10-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 9 223 2.2E-74 T 10-03-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 Pfam PF00035 Double-stranded RNA binding motif 156 223 9.9E-15 T 10-03-2017 IPR014720 Double-stranded RNA-binding domain RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 SMART SM00535 21 149 9.5E-60 T 10-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 SUPERFAMILY SSF54768 109 223 2.04E-27 T 10-03-2017 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 SUPERFAMILY SSF69065 5 159 1.69E-50 T 10-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 RG49_RS22210 b81a8841be34ad90cf46589e02b5db5e 226 Gene3D G3DSA:1.10.1520.10 6 148 2.3E-48 T 10-03-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 1.8E-45 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 SUPERFAMILY SSF64518 1 313 1.7E-109 T 10-03-2017 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 SUPERFAMILY SSF64518 343 486 1.7E-109 T 10-03-2017 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 Gene3D G3DSA:1.20.1330.10 54 170 1.5E-59 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 Gene3D G3DSA:1.20.1330.10 388 442 1.5E-59 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 Pfam PF00700 Bacterial flagellin C-terminal helical region 401 485 5.1E-31 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 PRINTS PR00207 Flagellin signature 37 54 2.0E-32 T 10-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 PRINTS PR00207 Flagellin signature 111 134 2.0E-32 T 10-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 RG49_RS00285 1d63f8a04f556fc176ad4712d3dec151 486 PRINTS PR00207 Flagellin signature 76 95 2.0E-32 T 10-03-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Gene3D G3DSA:1.10.150.20 712 818 5.0E-37 T 10-03-2017 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Pfam PF01612 3'-5' exonuclease 330 517 3.8E-46 T 10-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SMART SM00474 330 517 3.1E-49 T 10-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SUPERFAMILY SSF47807 171 291 1.11E-29 T 10-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 845 861 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 813 824 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 700 723 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 655 677 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 791 802 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 754 779 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 678 693 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 730 743 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 875 888 1.6E-80 T 10-03-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SMART SM00482 686 892 1.1E-127 T 10-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SMART SM00279 173 208 1.2E-13 T 10-03-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SUPERFAMILY SSF53098 326 518 8.07E-57 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Gene3D G3DSA:3.40.50.1010 8 186 1.1E-73 T 10-03-2017 IPR029060 PIN domain-like RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Gene3D G3DSA:3.30.70.370 819 928 7.4E-70 T 10-03-2017 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Gene3D G3DSA:3.30.70.370 664 711 7.4E-70 T 10-03-2017 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Gene3D G3DSA:1.10.150.20 187 253 4.7E-25 T 10-03-2017 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 ProSitePatterns PS00447 DNA polymerase family A signature. 754 773 - T 10-03-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Gene3D G3DSA:1.20.1060.10 543 663 2.0E-37 T 10-03-2017 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SMART SM00475 7 268 1.4E-145 T 10-03-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Pfam PF00476 DNA polymerase family A 551 925 1.3E-161 T 10-03-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SUPERFAMILY SSF88723 7 170 4.21E-57 T 10-03-2017 IPR029060 PIN domain-like RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 9 170 2.9E-55 T 10-03-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 TIGRFAM TIGR00593 pola: DNA polymerase I 9 928 1.1E-290 T 10-03-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 SUPERFAMILY SSF56672 523 928 4.56E-165 T 10-03-2017 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Gene3D G3DSA:3.30.420.10 329 542 1.7E-88 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS14870 d4b6304ef42d71ca37fb08c06bae969d 928 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 271 1.9E-30 T 10-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 SUPERFAMILY SSF88946 15 122 2.75E-38 T 10-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 284 55.487 T 10-03-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 PRINTS PR00046 Major sigma-70 factor signature 77 90 4.9E-19 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 PRINTS PR00046 Major sigma-70 factor signature 232 244 4.9E-19 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 PRINTS PR00046 Major sigma-70 factor signature 267 278 4.9E-19 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 PRINTS PR00046 Major sigma-70 factor signature 252 267 4.9E-19 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 Gene3D G3DSA:1.10.10.10 224 282 9.4E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 281 3.9E-35 T 10-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 14 283 7.4E-130 T 10-03-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 SUPERFAMILY SSF88659 200 283 4.11E-19 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 Pfam PF04545 Sigma-70, region 4 228 280 7.3E-17 T 10-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 Gene3D G3DSA:1.10.601.10 15 122 1.0E-33 T 10-03-2017 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 PIRSF PIRSF000770 14 284 1.6E-33 T 10-03-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS17265 80fc84758c6f971322646c5516b8915f 284 Pfam PF04542 Sigma-70 region 2 53 122 5.3E-17 T 10-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS08120 e6bcf1e8bcf9075b917451d34e0761ec 209 Gene3D G3DSA:3.90.1530.10 48 150 6.3E-12 T 10-03-2017 RG49_RS08120 e6bcf1e8bcf9075b917451d34e0761ec 209 SMART SM00470 51 146 1.0E-16 T 10-03-2017 IPR003115 ParB/Sulfiredoxin RG49_RS08120 e6bcf1e8bcf9075b917451d34e0761ec 209 SUPERFAMILY SSF110849 49 179 2.27E-25 T 10-03-2017 IPR003115 ParB/Sulfiredoxin RG49_RS08120 e6bcf1e8bcf9075b917451d34e0761ec 209 Pfam PF02195 ParB-like nuclease domain 52 145 2.0E-17 T 10-03-2017 IPR003115 ParB/Sulfiredoxin RG49_RS19210 3fa7e8669f303c3b972b1d59e67a7154 134 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 19 127 1.1E-22 T 10-03-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III RG49_RS21045 3dbf2e28e039acdb27aba57a7e14a764 215 SUPERFAMILY SSF53639 1 212 1.43E-69 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS21045 3dbf2e28e039acdb27aba57a7e14a764 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 182 4.7E-48 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS21045 3dbf2e28e039acdb27aba57a7e14a764 215 Hamap MF_00987 L-fuculose phosphate aldolase [fucA]. 1 215 62.414 T 10-03-2017 IPR004782 L-fucose phosphate aldolase GO:0006004|GO:0008270|GO:0008738 KEGG: 00051+4.1.2.17|MetaCyc: PWY-5197 RG49_RS21045 3dbf2e28e039acdb27aba57a7e14a764 215 Gene3D G3DSA:3.40.225.10 1 210 1.2E-67 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS21045 3dbf2e28e039acdb27aba57a7e14a764 215 TIGRFAM TIGR01086 fucA: L-fuculose phosphate aldolase 2 215 1.4E-134 T 10-03-2017 IPR004782 L-fucose phosphate aldolase GO:0006004|GO:0008270|GO:0008738 KEGG: 00051+4.1.2.17|MetaCyc: PWY-5197 RG49_RS21045 3dbf2e28e039acdb27aba57a7e14a764 215 SMART SM01007 8 182 3.7E-68 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 Gene3D G3DSA:3.40.50.1860 1 113 5.3E-45 T 10-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 Gene3D G3DSA:3.40.50.1860 114 216 3.7E-33 T 10-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 SUPERFAMILY SSF53681 119 229 7.19E-31 T 10-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 193 203 - T 10-03-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 1.0E-55 T 10-03-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 10-03-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 229 3.5E-62 T 10-03-2017 IPR004380 Aspartate racemase GO:0006520|GO:0016855 RG49_RS20825 e01279673d2819e6f812a9636b3e1b19 230 SUPERFAMILY SSF53681 1 114 4.36E-36 T 10-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS19490 f9f917a1183296d395a359eb3f1a47a5 19 Pfam PF13956 Toxin Ibs, type I toxin-antitoxin system 1 19 7.7E-12 T 10-03-2017 IPR025881 Toxin Ibs RG49_RS21485 423b1dc960f530f19d34f8d311474fc7 255 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 131 147 - T 10-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21485 423b1dc960f530f19d34f8d311474fc7 255 SUPERFAMILY SSF56770 36 167 8.63E-50 T 10-03-2017 RG49_RS21485 423b1dc960f530f19d34f8d311474fc7 255 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 48 157 2.7E-23 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21485 423b1dc960f530f19d34f8d311474fc7 255 Gene3D G3DSA:3.40.50.700 37 161 1.3E-26 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS16295 2bf83ea01d6f83c16c0aaced1463fed0 319 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 315 2.4E-81 T 10-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 RG49_RS16295 2bf83ea01d6f83c16c0aaced1463fed0 319 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 317 1.2E-130 T 10-03-2017 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 RG49_RS16295 2bf83ea01d6f83c16c0aaced1463fed0 319 Gene3D G3DSA:3.40.50.2000 165 316 4.0E-37 T 10-03-2017 RG49_RS16295 2bf83ea01d6f83c16c0aaced1463fed0 319 Gene3D G3DSA:3.40.50.2000 1 159 1.1E-32 T 10-03-2017 RG49_RS16295 2bf83ea01d6f83c16c0aaced1463fed0 319 SUPERFAMILY SSF53756 1 318 4.33E-74 T 10-03-2017 RG49_RS16575 370d94848809cf71d304db4e5a11c8b3 332 SUPERFAMILY SSF89733 1 332 6.8E-95 T 10-03-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS16575 370d94848809cf71d304db4e5a11c8b3 332 Pfam PF02615 Malate/L-lactate dehydrogenase 3 330 5.8E-103 T 10-03-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS16575 370d94848809cf71d304db4e5a11c8b3 332 Gene3D G3DSA:1.10.1530.10 1 73 6.2E-28 T 10-03-2017 RG49_RS16575 370d94848809cf71d304db4e5a11c8b3 332 Gene3D G3DSA:3.30.60.50 181 219 5.6E-25 T 10-03-2017 RG49_RS16575 370d94848809cf71d304db4e5a11c8b3 332 Gene3D G3DSA:3.30.1370.60 74 170 9.5E-57 T 10-03-2017 RG49_RS16575 370d94848809cf71d304db4e5a11c8b3 332 Gene3D G3DSA:3.30.1370.60 220 269 9.5E-57 T 10-03-2017 RG49_RS16575 370d94848809cf71d304db4e5a11c8b3 332 Hamap MF_00820 2,3-diketo-L-gulonate reductase [dlgD]. 1 332 89.623 T 10-03-2017 IPR023689 2,3-diketo-L-gulonate reductase GO:0016616|GO:0047559|GO:0055114|GO:0070403 KEGG: 00040+1.1.1.13+1.1.1.130|KEGG: 00053+1.1.1.130|MetaCyc: PWY-6961 RG49_RS10370 d0cbe8c2245fb552729d9d3fad2284ab 108 SUPERFAMILY SSF46785 3 69 1.29E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS10370 d0cbe8c2245fb552729d9d3fad2284ab 108 Pfam PF01726 LexA DNA binding domain 1 65 2.5E-19 T 10-03-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 RG49_RS10370 d0cbe8c2245fb552729d9d3fad2284ab 108 Gene3D G3DSA:1.10.10.10 1 68 1.2E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22425 ecad0a2b61665c6066ff039f2211b326 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 126 5.3E-72 T 10-03-2017 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 RG49_RS22425 ecad0a2b61665c6066ff039f2211b326 128 Gene3D G3DSA:3.90.1010.10 2 126 1.0E-57 T 10-03-2017 RG49_RS22425 ecad0a2b61665c6066ff039f2211b326 128 SUPERFAMILY SSF82649 1 125 1.2E-49 T 10-03-2017 RG49_RS22425 ecad0a2b61665c6066ff039f2211b326 128 Pfam PF01592 NifU-like N terminal domain 2 126 1.0E-57 T 10-03-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 RG49_RS07990 517e3156f8daab3c0acb16381316f506 127 TIGRFAM TIGR00494 crcB: protein CrcB 6 121 4.7E-45 T 10-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 RG49_RS07990 517e3156f8daab3c0acb16381316f506 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 122 19.442 T 10-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 RG49_RS07990 517e3156f8daab3c0acb16381316f506 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 116 9.3E-24 T 10-03-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 RG49_RS15010 6e9a9329195f38a369342462144b9103 546 Gene3D G3DSA:3.30.200.20 193 228 4.8E-4 T 10-03-2017 RG49_RS15010 6e9a9329195f38a369342462144b9103 546 Gene3D G3DSA:3.30.200.20 127 157 4.8E-4 T 10-03-2017 RG49_RS15010 6e9a9329195f38a369342462144b9103 546 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 7 446 1.9E-187 T 10-03-2017 IPR010232 Probable protein kinase UbiB GO:0006744 RG49_RS15010 6e9a9329195f38a369342462144b9103 546 SUPERFAMILY SSF56112 94 159 2.56E-49 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS15010 6e9a9329195f38a369342462144b9103 546 SUPERFAMILY SSF56112 194 438 2.56E-49 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS15010 6e9a9329195f38a369342462144b9103 546 Pfam PF03109 ABC1 family 116 232 1.2E-34 T 10-03-2017 IPR004147 UbiB domain RG49_RS15010 6e9a9329195f38a369342462144b9103 546 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 542 56.841 T 10-03-2017 IPR010232 Probable protein kinase UbiB GO:0006744 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 ProSitePatterns PS00538 Bacterial chemotaxis sensory transducers signature. 302 324 - T 10-03-2017 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 SMART SM00319 47 186 5.4E-52 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 SMART SM00283 277 524 2.5E-91 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 SUPERFAMILY SSF58104 244 526 2.62E-72 T 10-03-2017 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 Gene3D G3DSA:1.10.287.950 292 496 2.1E-60 T 10-03-2017 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 SUPERFAMILY SSF47170 27 176 8.5E-28 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 Pfam PF02203 Tar ligand binding domain homologue 11 177 1.4E-36 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 Gene3D G3DSA:1.20.120.30 62 164 2.1E-8 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 336 523 3.9E-66 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 SMART SM00304 224 276 2.4E-10 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 15 40 1.3E-59 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 298 327 1.3E-59 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 452 481 1.3E-59 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 70 85 1.3E-59 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 1.3E-59 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 1.3E-59 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS03310 c8b44c0043dde9ce0997dc74440e17fb 546 Pfam PF00672 HAMP domain 205 271 2.1E-14 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 SUPERFAMILY SSF46548 6 82 6.45E-17 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 TIGRFAM TIGR03379 glycerol3P_GlpC: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit 3 395 2.7E-231 T 10-03-2017 IPR017753 Glycerol-3-phosphate dehydrogenase, GlpC subunit GO:0006810|GO:0016020 RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 56 67 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 Gene3D G3DSA:1.10.1060.10 6 84 5.3E-16 T 10-03-2017 RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 Pfam PF02754 Cysteine-rich domain 163 249 1.1E-15 T 10-03-2017 IPR004017 Cysteine-rich domain RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 Pfam PF02754 Cysteine-rich domain 293 376 1.6E-14 T 10-03-2017 IPR004017 Cysteine-rich domain RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 Pfam PF13183 4Fe-4S dicluster domain 6 70 2.6E-10 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS23885 8882723c09e389ce65ef441feaedcfc6 396 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 547 41.614 T 10-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 Gene3D G3DSA:3.50.7.10 189 368 6.0E-99 T 10-03-2017 IPR027409 GroEL-like apical domain RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 SUPERFAMILY SSF48592 406 521 5.88E-78 T 10-03-2017 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 SUPERFAMILY SSF48592 7 134 5.88E-78 T 10-03-2017 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 2.2E-94 T 10-03-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 10-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 10-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 10-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 10-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 10-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 SUPERFAMILY SSF54849 137 203 1.42E-24 T 10-03-2017 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 Gene3D G3DSA:1.10.560.10 369 518 3.8E-40 T 10-03-2017 IPR027413 GroEL-like equatorial domain RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 Gene3D G3DSA:1.10.560.10 3 188 1.4E-47 T 10-03-2017 IPR027413 GroEL-like equatorial domain RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 SUPERFAMILY SSF52029 185 376 3.14E-83 T 10-03-2017 IPR027409 GroEL-like apical domain RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 2.2E-257 T 10-03-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 RG49_RS13210 6279ec3722197af3533a9fd2b8d54074 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 10-03-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.4E-24 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 45 61 1.4E-24 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 20 36 1.4E-24 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 63 75 1.4E-24 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 78 9.0E-30 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 SUPERFAMILY SSF159127 1 76 9.55E-24 T 10-03-2017 RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 Pfam PF01455 HupF/HypC family 1 72 4.0E-25 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS19810 3799010f2d3257da5915e46316f35c2e 82 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 10-03-2017 IPR019812 Hydrogenase assembly chaperone, conserved site RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 PRINTS PR00139 Asparaginase/glutaminase family signature 282 300 2.8E-23 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 PRINTS PR00139 Asparaginase/glutaminase family signature 26 37 2.8E-23 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 PRINTS PR00139 Asparaginase/glutaminase family signature 103 121 2.8E-23 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 104 114 - T 10-03-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 1 348 3.1E-170 T 10-03-2017 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 PIRSF PIRSF001220 20 348 1.8E-93 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 Gene3D G3DSA:3.40.50.1170 23 231 4.1E-76 T 10-03-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 PIRSF PIRSF500176 22 348 2.8E-82 T 10-03-2017 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 Pfam PF00710 Asparaginase, N-terminal 25 216 2.4E-63 T 10-03-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 SUPERFAMILY SSF53774 23 347 2.49E-109 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 SMART SM00870 25 342 4.4E-146 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 Gene3D G3DSA:3.40.50.40 235 346 3.5E-41 T 10-03-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 RG49_RS20100 5d38ca83cf0e360aa6e0c8a2ca52eece 348 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 28 36 - T 10-03-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 RG49_RS19950 497a3973469240019285341028188fd2 316 SUPERFAMILY SSF143865 1 255 4.71E-38 T 10-03-2017 RG49_RS19950 497a3973469240019285341028188fd2 316 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 3 316 2.3E-115 T 10-03-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 RG49_RS19950 497a3973469240019285341028188fd2 316 SUPERFAMILY SSF144083 251 314 9.29E-21 T 10-03-2017 RG49_RS19950 497a3973469240019285341028188fd2 316 Gene3D G3DSA:1.20.58.340 240 316 2.7E-28 T 10-03-2017 RG49_RS19950 497a3973469240019285341028188fd2 316 Pfam PF01544 CorA-like Mg2+ transporter protein 26 312 1.5E-57 T 10-03-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.8E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1033 0.0 T 10-03-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82714 182 271 4.45E-20 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82693 566 670 2.72E-32 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 Gene3D G3DSA:3.30.70.1430 38 139 8.5E-37 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82866 296 497 1.19E-47 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 Gene3D G3DSA:1.10.3850.10 278 498 9.1E-60 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 Gene3D G3DSA:1.10.3850.10 816 1030 2.3E-56 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 Gene3D G3DSA:3.30.2090.10 181 275 5.7E-24 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82693 136 182 5.49E-29 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82693 274 330 5.49E-29 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 Pfam PF00873 AcrB/AcrD/AcrF family 1 1029 0.0 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82714 725 810 1.18E-21 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 Gene3D G3DSA:3.30.2090.10 725 811 3.7E-27 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82693 38 132 3.77E-28 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 Gene3D G3DSA:3.30.70.1430 568 670 3.9E-40 T 10-03-2017 RG49_RS18270 927c198278aecbbd75555cad1b765f9c 1034 SUPERFAMILY SSF82866 808 1031 1.57E-44 T 10-03-2017 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 SUPERFAMILY SSF51569 4 319 1.03E-129 T 10-03-2017 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 SMART SM01004 3 321 1.2E-211 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 Gene3D G3DSA:3.20.20.70 2 319 3.9E-139 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 1.2E-54 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 240 256 1.2E-54 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 1.2E-54 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 265 280 1.2E-54 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 295 314 1.2E-54 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 1.2E-54 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 PIRSF PIRSF001415 1 323 5.6E-150 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 240 252 - T 10-03-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS09285 28ea057f2be462c5d1aa36c12293c25a 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 319 1.8E-136 T 10-03-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 TIGRFAM TIGR00861 MIP: MIP family channel proteins 13 251 4.7E-76 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 PRINTS PR00783 Major intrinsic protein family signature 234 254 6.5E-52 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 PRINTS PR00783 Major intrinsic protein family signature 9 28 6.5E-52 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 PRINTS PR00783 Major intrinsic protein family signature 48 72 6.5E-52 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 PRINTS PR00783 Major intrinsic protein family signature 184 206 6.5E-52 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 PRINTS PR00783 Major intrinsic protein family signature 151 169 6.5E-52 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 PRINTS PR00783 Major intrinsic protein family signature 85 104 6.5E-52 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 ProSitePatterns PS00221 MIP family signature. 66 74 - T 10-03-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 SUPERFAMILY SSF81338 9 257 1.7E-79 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 Gene3D G3DSA:1.20.1080.10 4 258 1.9E-86 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS14490 68d36bdf68da9f1e979bef074c6ede8a 281 Pfam PF00230 Major intrinsic protein 2 251 1.7E-77 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 501 529 - T 10-03-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 Gene3D G3DSA:1.25.20.10 29 389 9.4E-125 T 10-03-2017 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 SUPERFAMILY SSF48435 28 477 3.27E-137 T 10-03-2017 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 Pfam PF01464 Transglycosylase SLT domain 483 595 4.1E-34 T 10-03-2017 IPR008258 Transglycosylase SLT domain 1 RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 Gene3D G3DSA:1.10.530.10 475 639 2.2E-54 T 10-03-2017 RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 SUPERFAMILY SSF53955 479 641 8.13E-52 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 Pfam PF14718 Soluble lytic murein transglycosylase L domain 407 472 4.4E-23 T 10-03-2017 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 RG49_RS11945 f48d9284c13691149f750dbb3f673a78 645 Gene3D G3DSA:1.10.1240.20 404 472 4.2E-30 T 10-03-2017 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 Pfam PF02080 TrkA-C domain 326 390 1.3E-10 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 Pfam PF02080 TrkA-C domain 231 304 6.5E-13 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 558 574 - T 10-03-2017 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 SUPERFAMILY SSF116726 321 391 7.19E-16 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 SUPERFAMILY SSF116726 231 292 2.62E-8 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 Gene3D G3DSA:3.30.70.1450 232 311 7.4E-17 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 Gene3D G3DSA:3.30.70.1450 322 395 3.5E-20 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 Pfam PF03600 Citrate transporter 16 197 8.8E-36 T 10-03-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 RG49_RS23625 22ba4674fa614ae3ba2cdbee95c8a3fd 610 Pfam PF03600 Citrate transporter 430 608 2.5E-19 T 10-03-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 RG49_RS22870 a54cf3debf4909f8c8fbfcf2cba43d17 233 Pfam PF06249 Ethanolamine utilisation protein EutQ 85 232 4.5E-70 T 10-03-2017 IPR010424 Ethanolamine utilisation EutQ RG49_RS22870 a54cf3debf4909f8c8fbfcf2cba43d17 233 Gene3D G3DSA:2.60.120.10 102 232 1.5E-49 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS22870 a54cf3debf4909f8c8fbfcf2cba43d17 233 SUPERFAMILY SSF51182 108 230 1.02E-28 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS04430 fca79e291204297a9c2134d6157ee2b0 337 SMART SM00448 8 120 1.3E-28 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS04430 fca79e291204297a9c2134d6157ee2b0 337 Pfam PF00072 Response regulator receiver domain 10 120 2.6E-28 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS04430 fca79e291204297a9c2134d6157ee2b0 337 Hamap MF_00958 Regulator of RpoS [rssB]. 1 337 55.331 T 10-03-2017 IPR028616 Regulator of RpoS RG49_RS04430 fca79e291204297a9c2134d6157ee2b0 337 Gene3D G3DSA:3.40.50.2300 7 124 1.7E-30 T 10-03-2017 RG49_RS04430 fca79e291204297a9c2134d6157ee2b0 337 SUPERFAMILY SSF52172 8 128 1.04E-31 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 10-03-2017 IPR018336 Ribonuclease PH, conserved site RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 3.3E-24 T 10-03-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 SUPERFAMILY SSF55666 153 236 2.88E-26 T 10-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 49.994 T 10-03-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 7.2E-115 T 10-03-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 Gene3D G3DSA:3.30.230.70 9 237 2.3E-35 T 10-03-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 SUPERFAMILY SSF54211 1 181 4.61E-46 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS16185 f76fd2f1efd77178f5064df0cd03a31d 238 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 1.6E-12 T 10-03-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 Gene3D G3DSA:3.30.390.30 336 462 2.3E-44 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 7 460 5.9E-151 T 10-03-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 SUPERFAMILY SSF51905 2 338 6.17E-58 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 328 3.7E-63 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 Gene3D G3DSA:3.50.50.60 152 271 7.6E-36 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.3E-69 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 Gene3D G3DSA:3.50.50.60 272 335 3.6E-68 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 Gene3D G3DSA:3.50.50.60 6 149 3.6E-68 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PIRSF PIRSF000350 1 468 3.2E-87 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 10-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 3.8E-41 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 3.8E-41 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.8E-41 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.8E-41 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.8E-41 T 10-03-2017 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 SUPERFAMILY SSF55424 343 466 8.42E-39 T 10-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 RG49_RS11275 631f444eb319baaf657cb7836d934fa5 474 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 4.1E-35 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 SUPERFAMILY SSF52540 3 415 3.0E-139 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Gene3D G3DSA:4.10.860.10 622 670 5.6E-19 T 10-03-2017 IPR001943 UVR domain GO:0005515 RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 SUPERFAMILY SSF46600 624 669 1.31E-11 T 10-03-2017 IPR001943 UVR domain GO:0005515 RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Pfam PF00271 Helicase conserved C-terminal domain 434 545 1.1E-18 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Gene3D G3DSA:3.40.50.300 419 582 5.6E-39 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 SMART SM00487 9 425 6.3E-28 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 SUPERFAMILY SSF52540 459 581 1.07E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 SUPERFAMILY SSF52540 37 82 1.07E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Pfam PF04851 Type III restriction enzyme, res subunit 13 92 2.3E-9 T 10-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Gene3D G3DSA:3.40.50.300 278 338 1.2E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Gene3D G3DSA:3.40.50.300 5 89 1.2E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Gene3D G3DSA:3.40.50.300 388 408 1.2E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 666 0.0 T 10-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Pfam PF12344 Ultra-violet resistance protein B 552 593 1.1E-21 T 10-03-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 668 44.417 T 10-03-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 SMART SM00490 460 546 3.8E-20 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Pfam PF02151 UvrB/uvrC motif 634 667 1.7E-6 T 10-03-2017 IPR001943 UVR domain GO:0005515 RG49_RS07135 ec0a6df625d8492ad92d6b933cb6f65f 673 Gene3D G3DSA:3.30.2060.10 159 231 6.9E-11 T 10-03-2017 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 Gene3D G3DSA:3.40.50.2300 25 224 4.0E-65 T 10-03-2017 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 254 272 4.7E-69 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 88 98 4.7E-69 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 277 290 4.7E-69 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 4.7E-69 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 327 342 4.7E-69 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 4.7E-69 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 4.7E-69 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 SUPERFAMILY SSF53822 24 358 1.95E-88 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS17270 ca23063cf277647e08c6101f172e4bf5 367 Pfam PF13458 Periplasmic binding protein 26 344 7.9E-57 T 10-03-2017 IPR028081 Leucine-binding protein domain RG49_RS04650 4231711d4aa58b4fb6793a29453a8390 356 Pfam PF02733 Dak1 domain 18 351 1.8E-127 T 10-03-2017 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 RG49_RS04650 4231711d4aa58b4fb6793a29453a8390 356 Gene3D G3DSA:3.30.1180.20 185 355 3.9E-69 T 10-03-2017 RG49_RS04650 4231711d4aa58b4fb6793a29453a8390 356 SUPERFAMILY SSF82549 10 355 3.92E-127 T 10-03-2017 RG49_RS04650 4231711d4aa58b4fb6793a29453a8390 356 Gene3D G3DSA:3.40.50.10440 12 182 2.0E-69 T 10-03-2017 RG49_RS04650 4231711d4aa58b4fb6793a29453a8390 356 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 352 2.8E-157 T 10-03-2017 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 RG49_RS04080 3a35ecfae93ed0f514fe6665bc105bdc 547 PIRSF PIRSF002741 1 543 3.5E-93 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS04080 3a35ecfae93ed0f514fe6665bc105bdc 547 Gene3D G3DSA:3.10.105.10 293 508 4.5E-54 T 10-03-2017 RG49_RS04080 3a35ecfae93ed0f514fe6665bc105bdc 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 457 1.2E-83 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS04080 3a35ecfae93ed0f514fe6665bc105bdc 547 Gene3D G3DSA:3.90.76.10 44 223 1.5E-44 T 10-03-2017 RG49_RS04080 3a35ecfae93ed0f514fe6665bc105bdc 547 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 84 106 - T 10-03-2017 IPR023765 Solute-binding protein family 5, conserved site RG49_RS04080 3a35ecfae93ed0f514fe6665bc105bdc 547 SUPERFAMILY SSF53850 36 537 5.43E-133 T 10-03-2017 RG49_RS23855 e64eb0a9e0852d8c674525b8f146f74d 260 Pfam PF09339 IclR helix-turn-helix domain 9 58 1.7E-8 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS23855 e64eb0a9e0852d8c674525b8f146f74d 260 SMART SM00346 7 95 2.5E-33 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS23855 e64eb0a9e0852d8c674525b8f146f74d 260 SUPERFAMILY SSF46785 7 79 2.35E-10 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23855 e64eb0a9e0852d8c674525b8f146f74d 260 Pfam PF01614 Bacterial transcriptional regulator 122 247 5.7E-42 T 10-03-2017 IPR014757 Transcription regulator IclR, C-terminal RG49_RS23855 e64eb0a9e0852d8c674525b8f146f74d 260 SUPERFAMILY SSF55781 72 251 2.94E-48 T 10-03-2017 IPR029016 GAF domain-like RG49_RS23855 e64eb0a9e0852d8c674525b8f146f74d 260 Gene3D G3DSA:3.30.450.40 77 254 6.1E-66 T 10-03-2017 IPR029016 GAF domain-like RG49_RS23855 e64eb0a9e0852d8c674525b8f146f74d 260 Gene3D G3DSA:1.10.10.10 5 76 1.1E-12 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 313 328 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Gene3D G3DSA:1.10.8.60 400 450 1.9E-16 T 10-03-2017 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 SUPERFAMILY SSF52540 217 461 2.39E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Pfam PF02954 Bacterial regulatory protein, Fis family 498 527 2.5E-10 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 8 528 5.2E-268 T 10-03-2017 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 SMART SM00382 238 391 1.9E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Gene3D G3DSA:3.40.50.2300 1 99 9.7E-47 T 10-03-2017 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Gene3D G3DSA:1.10.10.60 451 527 2.4E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 SUPERFAMILY SSF159800 12 195 6.28E-54 T 10-03-2017 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Pfam PF00158 Sigma-54 interaction domain 219 393 1.5E-64 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Gene3D G3DSA:3.40.50.10660 100 176 5.8E-37 T 10-03-2017 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Pfam PF06506 Propionate catabolism activator 36 196 5.5E-51 T 10-03-2017 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Gene3D G3DSA:3.40.50.300 221 399 6.8E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 SUPERFAMILY SSF46689 444 527 1.61E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 444 453 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS09490 f12fc4ce8dbcd6c527cbfadbbc6f1141 528 Gene3D G3DSA:1.20.5.170 178 220 2.9E-28 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 SUPERFAMILY SSF48557 3 456 2.04E-143 T 10-03-2017 IPR008948 L-Aspartase-like GO:0003824 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 2.4E-29 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 2.4E-29 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 2.4E-29 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.4E-29 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS14310 7442579a7f9797c55678402dbb898539 457 Gene3D G3DSA:1.20.200.10 108 374 7.2E-105 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 7.6E-25 T 10-03-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 10-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 Gene3D G3DSA:1.10.275.10 1 107 1.5E-37 T 10-03-2017 IPR024083 Fumarase/histidase, N-terminal RG49_RS14310 7442579a7f9797c55678402dbb898539 457 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 456 2.2E-216 T 10-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 4.0E-68 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 4.0E-68 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 4.0E-68 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 4.0E-68 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 4.0E-68 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 4.0E-68 T 10-03-2017 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 454 41.784 T 10-03-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS14310 7442579a7f9797c55678402dbb898539 457 Pfam PF00206 Lyase 6 301 5.3E-101 T 10-03-2017 IPR022761 Fumarate lyase, N-terminal RG49_RS14310 7442579a7f9797c55678402dbb898539 457 Gene3D G3DSA:1.10.40.30 375 432 6.8E-31 T 10-03-2017 RG49_RS16995 f52aff88fe8b06ac07e41a3429b6e6ff 112 Gene3D G3DSA:1.10.890.10 28 101 1.0E-8 T 10-03-2017 IPR010486 HNS-dependent expression A/B RG49_RS16995 f52aff88fe8b06ac07e41a3429b6e6ff 112 Pfam PF06411 HdeA/HdeB family 19 100 4.9E-24 T 10-03-2017 IPR010486 HNS-dependent expression A/B RG49_RS16995 f52aff88fe8b06ac07e41a3429b6e6ff 112 Hamap MF_00947 Acid stress chaperone HdeB [hdeB]. 6 107 26.215 T 10-03-2017 IPR028623 HNS-dependent expression B GO:0009268|GO:0051082 RG49_RS16995 f52aff88fe8b06ac07e41a3429b6e6ff 112 ProDom PD070929 HDEB PRECURSOR SIGNAL EXPORTED PERIPLASMIC SECRETED ECS4389 10K-L SEQUENCING DIRECT 5 112 2.0E-59 T 10-03-2017 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Pfam PF00994 Probable molybdopterin binding domain 182 317 1.7E-27 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Gene3D G3DSA:2.40.340.10 330 402 5.4E-35 T 10-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 168 5.6E-40 T 10-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 254 287 - T 10-03-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 SUPERFAMILY SSF63882 7 177 3.66E-59 T 10-03-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 SMART SM00852 181 318 4.9E-44 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS06870 24af2606f845ed90251c27746549ab43 411 SUPERFAMILY SSF63867 328 407 5.23E-25 T 10-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Gene3D G3DSA:3.40.980.10 164 327 8.8E-65 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS06870 24af2606f845ed90251c27746549ab43 411 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 177 314 3.6E-34 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Gene3D G3DSA:3.90.105.10 143 163 1.7E-25 T 10-03-2017 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Gene3D G3DSA:3.90.105.10 27 50 1.7E-25 T 10-03-2017 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Gene3D G3DSA:2.170.190.11 51 142 3.4E-35 T 10-03-2017 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 Pfam PF03454 MoeA C-terminal region (domain IV) 332 404 2.9E-21 T 10-03-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS06870 24af2606f845ed90251c27746549ab43 411 SUPERFAMILY SSF53218 178 321 7.85E-44 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS18090 f3f9af9f0f3baa9ec3319b1573a90dfc 59 SUPERFAMILY SSF55129 3 59 3.01E-21 T 10-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain RG49_RS18090 f3f9af9f0f3baa9ec3319b1573a90dfc 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 22.049 T 10-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 RG49_RS18090 f3f9af9f0f3baa9ec3319b1573a90dfc 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 2.9E-19 T 10-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain RG49_RS18090 f3f9af9f0f3baa9ec3319b1573a90dfc 59 Gene3D G3DSA:3.30.1390.20 2 59 1.7E-30 T 10-03-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain RG49_RS18090 f3f9af9f0f3baa9ec3319b1573a90dfc 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 1.6E-28 T 10-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 RG49_RS18090 f3f9af9f0f3baa9ec3319b1573a90dfc 59 PIRSF PIRSF002211 1 59 6.5E-30 T 10-03-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 RG49_RS18090 f3f9af9f0f3baa9ec3319b1573a90dfc 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 10-03-2017 IPR018038 Ribosomal protein L30, conserved site RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 TIGRFAM TIGR00260 thrC: threonine synthase 52 397 7.9E-131 T 10-03-2017 IPR004450 Threonine synthase-like RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 Gene3D G3DSA:3.90.1380.10 1 84 2.7E-22 T 10-03-2017 IPR029144 Threonine synthase, N-terminal RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 Gene3D G3DSA:3.40.50.1100 196 319 7.6E-52 T 10-03-2017 RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 Gene3D G3DSA:3.40.50.1100 324 401 2.3E-16 T 10-03-2017 RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 97 111 - T 10-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 SUPERFAMILY SSF53686 1 426 2.75E-132 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 Pfam PF14821 Threonine synthase N terminus 8 80 7.5E-14 T 10-03-2017 IPR029144 Threonine synthase, N-terminal RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 97 369 4.9E-24 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS11870 b4dd51958f3c7a7a21e0f222dcbbd764 428 Gene3D G3DSA:3.40.50.1100 106 195 1.3E-12 T 10-03-2017 RG49_RS01055 ce5689cd00b5ab7203100f59fffa568a 496 Pfam PF17155 Gammaproteobacterial periplasmic sensor domain 31 304 5.1E-150 T 10-03-2017 IPR033420 Gammaproteobacterial periplasmic sensor domain GAPES1 RG49_RS01055 ce5689cd00b5ab7203100f59fffa568a 496 Pfam PF00990 Diguanylate cyclase, GGDEF domain 346 494 1.7E-39 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01055 ce5689cd00b5ab7203100f59fffa568a 496 SUPERFAMILY SSF55073 349 495 1.88E-32 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS01055 ce5689cd00b5ab7203100f59fffa568a 496 Gene3D G3DSA:3.30.70.270 347 494 1.9E-34 T 10-03-2017 RG49_RS01055 ce5689cd00b5ab7203100f59fffa568a 496 SMART SM00267 333 496 2.9E-46 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01055 ce5689cd00b5ab7203100f59fffa568a 496 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 343 495 1.2E-35 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01055 ce5689cd00b5ab7203100f59fffa568a 496 Gene3D G3DSA:3.30.450.20 192 241 2.1E-5 T 10-03-2017 RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 PIRSF PIRSF037354 1 527 1.5E-298 T 10-03-2017 IPR017183 Sigma54-dependent transcriptional activator, RtcR GO:0003700|GO:0006355 RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 SUPERFAMILY SSF52540 186 438 2.06E-50 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 SMART SM00382 207 353 6.8E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 Pfam PF06956 Regulator of RNA terminal phosphate cyclase 2 185 1.2E-83 T 10-03-2017 IPR009715 Regulator of RNA terminal phosphate cyclase RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 Gene3D G3DSA:1.10.8.60 363 440 3.6E-12 T 10-03-2017 RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 Pfam PF00158 Sigma-54 interaction domain 187 354 3.8E-51 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 Gene3D G3DSA:3.40.50.300 184 359 1.6E-39 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17460 edd0f332dbb1b8d1fed4792d2fe3a069 532 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 276 291 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 Gene3D G3DSA:3.30.450.20 78 183 2.4E-14 T 10-03-2017 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 SUPERFAMILY SSF55785 82 174 1.47E-8 T 10-03-2017 IPR000014 PAS domain RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 SMART SM00091 80 147 2.1E-4 T 10-03-2017 IPR000014 PAS domain RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 SUPERFAMILY SSF46689 454 507 4.93E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 SUPERFAMILY SSF55021 2 69 3.51E-5 T 10-03-2017 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 Pfam PF00158 Sigma-54 interaction domain 207 365 1.3E-55 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 Gene3D G3DSA:3.40.50.300 203 371 1.1E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 Gene3D G3DSA:3.30.70.260 2 68 2.3E-5 T 10-03-2017 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 Gene3D G3DSA:1.10.10.60 450 507 2.2E-28 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 SMART SM00382 226 363 3.2E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 SUPERFAMILY SSF52540 206 440 1.33E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 460 507 2.3E-28 T 10-03-2017 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 230 243 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 285 300 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 Gene3D G3DSA:1.10.8.60 372 442 7.0E-19 T 10-03-2017 RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 Pfam PF13188 PAS domain 82 135 6.8E-5 T 10-03-2017 IPR000014 PAS domain RG49_RS03925 2d30e9c6a468d54a6af5c09e8e9ff6b1 513 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 412 421 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS08985 0716002e1951c2c2400be1af5dd06537 109 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 92 4.7E-19 T 10-03-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 RG49_RS08985 0716002e1951c2c2400be1af5dd06537 109 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 12 107 4.5E-38 T 10-03-2017 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 RG49_RS11640 b7dfd486a24cdf66bca7ff9b4c27866d 443 SUPERFAMILY SSF103473 8 429 1.83E-76 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS11640 b7dfd486a24cdf66bca7ff9b4c27866d 443 Pfam PF00083 Sugar (and other) transporter 32 433 3.9E-52 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS11640 b7dfd486a24cdf66bca7ff9b4c27866d 443 Gene3D G3DSA:1.20.1250.20 243 426 1.1E-15 T 10-03-2017 RG49_RS11640 b7dfd486a24cdf66bca7ff9b4c27866d 443 Gene3D G3DSA:1.20.1250.20 17 201 4.3E-29 T 10-03-2017 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 10-03-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 Pfam PF00849 RNA pseudouridylate synthase 69 195 3.5E-14 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 SUPERFAMILY SSF55120 69 229 1.1E-38 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 226 2.0E-54 T 10-03-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 SMART SM00363 7 68 1.3E-13 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 SUPERFAMILY SSF55174 7 62 5.72E-14 T 10-03-2017 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 Gene3D G3DSA:3.10.290.10 6 60 6.0E-21 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS13955 18085dc49132ac66c5998c97ebbf1595 290 Pfam PF01479 S4 domain 7 52 5.5E-14 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.3E-15 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 Gene3D G3DSA:1.10.10.10 2 82 5.2E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 Pfam PF03466 LysR substrate binding domain 86 286 1.0E-53 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 Gene3D G3DSA:3.40.190.10 87 173 2.3E-18 T 10-03-2017 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 Gene3D G3DSA:3.40.190.10 174 254 1.0E-19 T 10-03-2017 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 SUPERFAMILY SSF53850 88 286 1.18E-49 T 10-03-2017 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.2E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.2E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.2E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS24370 cc3e6fb6928dbf30678f50efdfaf37a0 293 SUPERFAMILY SSF46785 2 109 2.18E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21015 cf263bc6440a4d61df51f2a700d06fc6 366 Gene3D G3DSA:3.40.50.150 184 316 5.2E-15 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS21015 cf263bc6440a4d61df51f2a700d06fc6 366 SUPERFAMILY SSF53335 184 296 3.09E-13 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS21015 cf263bc6440a4d61df51f2a700d06fc6 366 PIRSF PIRSF028774 1 360 8.6E-193 T 10-03-2017 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 RG49_RS21015 cf263bc6440a4d61df51f2a700d06fc6 366 Pfam PF01728 FtsJ-like methyltransferase 186 279 3.2E-8 T 10-03-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 RG49_RS21015 cf263bc6440a4d61df51f2a700d06fc6 366 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 1 355 87.539 T 10-03-2017 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 Pfam PF00294 pfkB family carbohydrate kinase 2 286 1.2E-67 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 PRINTS PR00990 Ribokinase signature 33 52 7.3E-5 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 PRINTS PR00990 Ribokinase signature 209 220 7.3E-5 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 PRINTS PR00990 Ribokinase signature 6 27 7.3E-5 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 Gene3D G3DSA:3.40.1190.20 2 295 2.1E-82 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 Hamap MF_00999 Sulfofructose kinase. 1 298 64.922 T 10-03-2017 IPR030877 Sulfofructose kinase GO:0061594 MetaCyc: PWY-7446 RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 238 251 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS14755 acb7fc0a3d77694e60b2c3438edbb296 298 SUPERFAMILY SSF53613 1 293 4.37E-68 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Gene3D G3DSA:1.10.3650.10 360 435 3.5E-33 T 10-03-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Pfam PF13247 4Fe-4S dicluster domain 176 272 9.7E-38 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 359 437 3.8E-31 T 10-03-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Gene3D G3DSA:3.30.70.20 237 359 4.0E-77 T 10-03-2017 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Gene3D G3DSA:3.30.70.20 437 466 4.0E-77 T 10-03-2017 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Gene3D G3DSA:3.30.70.20 174 194 1.3E-17 T 10-03-2017 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Gene3D G3DSA:3.30.70.20 5 53 1.3E-17 T 10-03-2017 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 SUPERFAMILY SSF54862 1 504 1.99E-188 T 10-03-2017 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 Gene3D G3DSA:3.30.70.20 195 236 2.6E-25 T 10-03-2017 RG49_RS04490 90c20a6fec80bfc20c0cc5717f0a9965 512 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 493 0.0 T 10-03-2017 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 265 2.4E-72 T 10-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Gene3D G3DSA:3.40.50.300 2 104 4.0E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Gene3D G3DSA:3.40.50.300 182 279 4.0E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Gene3D G3DSA:3.40.50.300 280 382 8.7E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Gene3D G3DSA:3.40.50.300 550 637 8.7E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Gene3D G3DSA:1.10.486.10 383 525 6.3E-41 T 10-03-2017 RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 SUPERFAMILY SSF52540 2 636 1.06E-162 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 2 667 0.0 T 10-03-2017 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Gene3D G3DSA:1.10.10.160 108 181 2.2E-24 T 10-03-2017 IPR013986 DExx box DNA helicase domain RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 1 668 41.121 T 10-03-2017 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 RG49_RS15330 9e4addbe6adadd3728696f7fb5d84601 673 Pfam PF13361 UvrD-like helicase C-terminal domain 271 613 7.9E-71 T 10-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 RG49_RS18810 3bd4474276d81e34a5f41940e5023c8f 133 Gene3D G3DSA:3.30.300.20 1 107 9.5E-40 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS18810 3bd4474276d81e34a5f41940e5023c8f 133 SUPERFAMILY SSF89919 2 107 4.97E-36 T 10-03-2017 IPR023799 Ribosome-binding factor A domain RG49_RS18810 3bd4474276d81e34a5f41940e5023c8f 133 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 119 2.4E-45 T 10-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 RG49_RS18810 3bd4474276d81e34a5f41940e5023c8f 133 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 120 23.311 T 10-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 RG49_RS18810 3bd4474276d81e34a5f41940e5023c8f 133 Pfam PF02033 Ribosome-binding factor A 7 112 1.3E-32 T 10-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 RG49_RS18810 3bd4474276d81e34a5f41940e5023c8f 133 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 10-03-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 RG49_RS18810 3bd4474276d81e34a5f41940e5023c8f 133 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 9.0E-48 T 10-03-2017 IPR000238 Ribosome-binding factor A GO:0006364 RG49_RS22865 460c6f166be6325e633d96f345c8106b 159 PIRSF PIRSF036409 1 148 1.1E-59 T 10-03-2017 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 RG49_RS22865 460c6f166be6325e633d96f345c8106b 159 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 144 1.1E-59 T 10-03-2017 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 RG49_RS22865 460c6f166be6325e633d96f345c8106b 159 Gene3D G3DSA:3.40.50.300 3 154 7.0E-15 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22865 460c6f166be6325e633d96f345c8106b 159 SUPERFAMILY SSF52540 3 148 4.25E-18 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22865 460c6f166be6325e633d96f345c8106b 159 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 1 143 5.1E-30 T 10-03-2017 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 RG49_RS16745 e74491a9b73a717ef4239142260ad8a5 232 SUPERFAMILY SSF103515 88 232 2.48E-11 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16745 e74491a9b73a717ef4239142260ad8a5 232 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 88 232 3.5E-5 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS16745 e74491a9b73a717ef4239142260ad8a5 232 Gene3D G3DSA:2.40.128.130 88 232 5.8E-9 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16745 e74491a9b73a717ef4239142260ad8a5 232 Pfam PF03797 Autotransporter beta-domain 90 215 2.4E-10 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16745 e74491a9b73a717ef4239142260ad8a5 232 PIRSF PIRSF030748 1 232 6.1E-151 T 10-03-2017 IPR016955 Autotransporter, YhjY, predicted RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 Pfam PF06574 FAD synthetase 13 168 6.0E-58 T 10-03-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 SMART SM00904 184 308 1.2E-61 T 10-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 307 1.5E-123 T 10-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 Gene3D G3DSA:3.40.50.620 1 180 2.6E-66 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 PIRSF PIRSF004491 1 312 8.9E-105 T 10-03-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 Gene3D G3DSA:2.40.30.30 181 307 4.1E-39 T 10-03-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 Pfam PF01687 Riboflavin kinase 185 307 4.1E-37 T 10-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 SUPERFAMILY SSF52374 17 177 6.19E-33 T 10-03-2017 RG49_RS11745 25ec4f764e87614d7859601d579758d8 313 SUPERFAMILY SSF82114 175 308 3.27E-43 T 10-03-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 RG49_RS15110 654589fbd0159975e9024582a2cf47d1 316 SUPERFAMILY SSF143865 1 255 4.71E-38 T 10-03-2017 RG49_RS15110 654589fbd0159975e9024582a2cf47d1 316 SUPERFAMILY SSF144083 251 314 1.31E-20 T 10-03-2017 RG49_RS15110 654589fbd0159975e9024582a2cf47d1 316 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 3 316 5.4E-115 T 10-03-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 RG49_RS15110 654589fbd0159975e9024582a2cf47d1 316 Pfam PF01544 CorA-like Mg2+ transporter protein 26 312 6.5E-57 T 10-03-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 RG49_RS15110 654589fbd0159975e9024582a2cf47d1 316 Gene3D G3DSA:1.20.58.340 240 316 2.6E-28 T 10-03-2017 RG49_RS02180 81f242018c6c87beeeca846fb3c3785b 339 Pfam PF00107 Zinc-binding dehydrogenase 171 297 8.0E-19 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS02180 81f242018c6c87beeeca846fb3c3785b 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 4.2E-36 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS02180 81f242018c6c87beeeca846fb3c3785b 339 Gene3D G3DSA:3.40.50.720 167 280 1.1E-23 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02180 81f242018c6c87beeeca846fb3c3785b 339 SUPERFAMILY SSF51735 137 304 1.73E-25 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02180 81f242018c6c87beeeca846fb3c3785b 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS02180 81f242018c6c87beeeca846fb3c3785b 339 SUPERFAMILY SSF50129 1 170 6.54E-53 T 10-03-2017 IPR011032 GroES-like RG49_RS02180 81f242018c6c87beeeca846fb3c3785b 339 Gene3D G3DSA:3.90.180.10 1 166 4.1E-57 T 10-03-2017 IPR011032 GroES-like RG49_RS03115 d2f575cc960ee90ad15ca4bb5b1f71b2 499 Pfam PF00324 Amino acid permease 35 476 1.9E-126 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS03115 d2f575cc960ee90ad15ca4bb5b1f71b2 499 PIRSF PIRSF006060 23 490 2.3E-66 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS03115 d2f575cc960ee90ad15ca4bb5b1f71b2 499 ProSitePatterns PS00218 Amino acid permeases signature. 59 89 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 SUPERFAMILY SSF54862 1 503 1.99E-181 T 10-03-2017 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 493 2.5E-296 T 10-03-2017 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Pfam PF13247 4Fe-4S dicluster domain 175 271 1.2E-37 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Gene3D G3DSA:3.30.70.20 196 235 4.2E-25 T 10-03-2017 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Gene3D G3DSA:1.10.3650.10 359 435 3.9E-31 T 10-03-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Gene3D G3DSA:3.30.70.20 10 26 5.9E-12 T 10-03-2017 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Gene3D G3DSA:3.30.70.20 159 195 5.9E-12 T 10-03-2017 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Gene3D G3DSA:3.30.70.20 437 466 1.3E-77 T 10-03-2017 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Gene3D G3DSA:3.30.70.20 236 358 1.3E-77 T 10-03-2017 RG49_RS03025 1c769a058f6972b9bc5b3f810a3ca296 514 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 436 9.9E-30 T 10-03-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.549 T 10-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 Gene3D G3DSA:3.30.860.10 1 91 8.0E-41 T 10-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 PIRSF PIRSF002144 1 92 1.7E-31 T 10-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 8.6E-46 T 10-03-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 Pfam PF00203 Ribosomal protein S19 3 83 2.3E-36 T 10-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 10-03-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.1E-25 T 10-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.1E-25 T 10-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.1E-25 T 10-03-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18020 75dc389130382ce3a8c6078ff4f868d1 92 SUPERFAMILY SSF54570 3 84 2.75E-35 T 10-03-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS20440 eb0f4b8c67311397f940dffaadeea5b8 577 SUPERFAMILY SSF64182 48 465 7.33E-117 T 10-03-2017 RG49_RS20440 eb0f4b8c67311397f940dffaadeea5b8 577 Pfam PF02272 DHHA1 domain 382 449 1.1E-15 T 10-03-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 RG49_RS20440 eb0f4b8c67311397f940dffaadeea5b8 577 Pfam PF01368 DHH family 74 211 6.4E-11 T 10-03-2017 IPR001667 DDH domain RG49_RS20440 eb0f4b8c67311397f940dffaadeea5b8 577 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 24 573 1.5E-170 T 10-03-2017 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 SUPERFAMILY SSF52540 821 1019 3.5E-15 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 SUPERFAMILY SSF52540 1 270 3.98E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 Pfam PF13476 AAA domain 5 206 1.9E-29 T 10-03-2017 RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 Gene3D G3DSA:3.40.50.300 910 1034 7.7E-37 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 Gene3D G3DSA:3.40.50.300 791 792 7.7E-37 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 Gene3D G3DSA:3.40.50.300 1 174 7.7E-37 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 SUPERFAMILY SSF52540 242 419 2.3E-9 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 SUPERFAMILY SSF52540 1 58 2.3E-9 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 TIGRFAM TIGR00618 sbcc: exonuclease SbcC 1 1039 0.0 T 10-03-2017 IPR004592 Nuclease SbcC, gammaproteobacteria type RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 Gene3D G3DSA:3.40.50.300 175 236 1.8E-4 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09145 f31ead8643cb9377ec5c89ed5be6b849 1047 Pfam PF13558 Putative exonuclease SbcCD, C subunit 930 1001 2.5E-15 T 10-03-2017 RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 SUPERFAMILY SSF103515 541 836 6.8E-46 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 SMART SM00869 572 825 4.4E-39 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 Gene3D G3DSA:2.40.128.130 533 836 2.6E-72 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 Pfam PF03797 Autotransporter beta-domain 571 819 1.6E-49 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 190 222 4.8E-5 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 82 111 1.2E-5 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 171 207 7.6E-7 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 SUPERFAMILY SSF51126 27 527 4.71E-42 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 Gene3D G3DSA:2.160.20.20 27 529 3.5E-64 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 PRINTS PR01484 Pertactin virulence factor family signature 816 836 2.9E-6 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 PRINTS PR01484 Pertactin virulence factor family signature 752 773 2.9E-6 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 PRINTS PR01484 Pertactin virulence factor family signature 723 746 2.9E-6 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 PRINTS PR01484 Pertactin virulence factor family signature 613 637 2.9E-6 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 429 836 5.2E-111 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 Pfam PF03212 Pertactin 403 528 6.1E-46 T 10-03-2017 IPR004899 Pertactin, central region RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 230 287 1.2E-19 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS24185 ff0bbf954e5556ee23ef0e210d2ce430 836 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 157 218 6.5E-24 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS13670 09027cec46ad382a3a6658eb9b92b207 549 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 178 203 - T 10-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS13670 09027cec46ad382a3a6658eb9b92b207 549 TIGRFAM TIGR02711 symport_actP: cation/acetate symporter ActP 2 549 0.0 T 10-03-2017 IPR014083 Cation/acetate symporter ActP GO:0005887|GO:0015123|GO:0043879 RG49_RS13670 09027cec46ad382a3a6658eb9b92b207 549 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 450 470 - T 10-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS13670 09027cec46ad382a3a6658eb9b92b207 549 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 63 466 7.9E-63 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS13670 09027cec46ad382a3a6658eb9b92b207 549 Hamap MF_01426 Cation/acetate symporter ActP [actP]. 1 549 60.851 T 10-03-2017 IPR014083 Cation/acetate symporter ActP GO:0005887|GO:0015123|GO:0043879 RG49_RS13670 09027cec46ad382a3a6658eb9b92b207 549 Pfam PF00474 Sodium:solute symporter family 63 468 2.0E-140 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS19345 3b1620e059d8bad80a31586fb0dc07aa 110 SUPERFAMILY SSF50249 8 109 3.67E-32 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS19345 3b1620e059d8bad80a31586fb0dc07aa 110 Gene3D G3DSA:2.40.50.140 2 109 9.8E-38 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS19345 3b1620e059d8bad80a31586fb0dc07aa 110 Pfam PF01588 Putative tRNA binding domain 14 107 1.6E-31 T 10-03-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 RG49_RS00410 60dc0244e61b9d9d23b4a68998386248 167 Gene3D G3DSA:1.20.1260.10 3 162 6.4E-37 T 10-03-2017 IPR012347 Ferritin-related RG49_RS00410 60dc0244e61b9d9d23b4a68998386248 167 SUPERFAMILY SSF47240 9 158 3.95E-35 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS00410 60dc0244e61b9d9d23b4a68998386248 167 Pfam PF00210 Ferritin-like domain 9 142 1.6E-25 T 10-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 663 725 2.8E-20 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 728 779 7.4E-9 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 205 267 1.0E-24 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 793 853 4.7E-20 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 610 651 1.1E-6 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 465 526 4.3E-21 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 371 433 9.5E-23 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 258 289 1.5E-6 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 293 325 6.5E-8 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 604 636 6.7E-5 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 808 837 3.6E-5 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 75 107 1.5E-7 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 4 38 9.2E-7 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 716 748 9.5E-8 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Gene3D G3DSA:2.160.20.20 699 892 3.7E-23 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Gene3D G3DSA:2.160.20.20 184 347 4.0E-29 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Gene3D G3DSA:2.160.20.20 388 440 4.0E-29 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Gene3D G3DSA:2.160.20.20 5 143 4.0E-29 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS21850 e86a3a988f07b801a52d20b95c0e5955 900 Gene3D G3DSA:2.160.20.20 562 656 3.7E-23 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 87 166 1.2E-38 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 SUPERFAMILY SSF53155 9 91 1.29E-5 T 10-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 88 167 3.2E-35 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 Gene3D G3DSA:1.10.10.10 86 168 4.0E-37 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 4 83 1.7E-19 T 10-03-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 4 169 40.038 T 10-03-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 SUPERFAMILY SSF46767 86 169 8.5E-34 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS03860 c97fb98b318e8514032a8d0ee98b8822 171 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 137 143 - T 10-03-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 RG49_RS05550 5eb5dcb98b9d094d8feb92ef24f843bd 271 Gene3D G3DSA:3.30.420.10 104 262 2.0E-35 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS05550 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF00665 Integrase core domain 109 223 6.6E-31 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS05550 5eb5dcb98b9d094d8feb92ef24f843bd 271 SUPERFAMILY SSF53098 103 265 1.07E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS05550 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF13276 HTH-like domain 36 84 1.9E-11 T 10-03-2017 IPR025948 HTH-like domain RG49_RS02755 5eb5dcb98b9d094d8feb92ef24f843bd 271 Gene3D G3DSA:3.30.420.10 104 262 2.0E-35 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS02755 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF00665 Integrase core domain 109 223 6.6E-31 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS02755 5eb5dcb98b9d094d8feb92ef24f843bd 271 SUPERFAMILY SSF53098 103 265 1.07E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS02755 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF13276 HTH-like domain 36 84 1.9E-11 T 10-03-2017 IPR025948 HTH-like domain RG49_RS03080 5eb5dcb98b9d094d8feb92ef24f843bd 271 Gene3D G3DSA:3.30.420.10 104 262 2.0E-35 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS03080 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF00665 Integrase core domain 109 223 6.6E-31 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS03080 5eb5dcb98b9d094d8feb92ef24f843bd 271 SUPERFAMILY SSF53098 103 265 1.07E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS03080 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF13276 HTH-like domain 36 84 1.9E-11 T 10-03-2017 IPR025948 HTH-like domain RG49_RS16490 5eb5dcb98b9d094d8feb92ef24f843bd 271 Gene3D G3DSA:3.30.420.10 104 262 2.0E-35 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS16490 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF00665 Integrase core domain 109 223 6.6E-31 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS16490 5eb5dcb98b9d094d8feb92ef24f843bd 271 SUPERFAMILY SSF53098 103 265 1.07E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS16490 5eb5dcb98b9d094d8feb92ef24f843bd 271 Pfam PF13276 HTH-like domain 36 84 1.9E-11 T 10-03-2017 IPR025948 HTH-like domain RG49_RS09645 5606b0ad845085d2901679303e1134de 231 SUPERFAMILY SSF100950 41 229 5.44E-38 T 10-03-2017 RG49_RS09645 5606b0ad845085d2901679303e1134de 231 Gene3D G3DSA:3.40.50.10420 42 228 9.7E-47 T 10-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain RG49_RS09645 5606b0ad845085d2901679303e1134de 231 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 65 228 9.9E-29 T 10-03-2017 IPR003741 LUD domain RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 SUPERFAMILY SSF51126 412 920 2.01E-42 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Gene3D G3DSA:2.40.128.130 936 1250 1.3E-69 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 807 1250 1.2E-116 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Pfam PF12951 Passenger-associated-transport-repeat 559 580 0.077 T 10-03-2017 IPR013425 Autotransporter-associated beta strand repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Pfam PF12951 Passenger-associated-transport-repeat 663 690 5.2E-4 T 10-03-2017 IPR013425 Autotransporter-associated beta strand repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Pfam PF12951 Passenger-associated-transport-repeat 328 355 5.0E-4 T 10-03-2017 IPR013425 Autotransporter-associated beta strand repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 TIGRFAM TIGR01376 POMP_repeat: chlamydial polymorphic outer membrane protein repeat 228 249 9.9E-5 T 10-03-2017 IPR003368 Polymorphic outer membrane protein repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 TIGRFAM TIGR01376 POMP_repeat: chlamydial polymorphic outer membrane protein repeat 124 146 4.6E-4 T 10-03-2017 IPR003368 Polymorphic outer membrane protein repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 SMART SM00869 984 1239 1.2E-35 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 SUPERFAMILY SSF51126 92 421 2.45E-8 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Pfam PF03797 Autotransporter beta-domain 985 1229 7.4E-40 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Pfam PF02415 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat 127 144 0.019 T 10-03-2017 IPR003368 Polymorphic outer membrane protein repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Pfam PF02415 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat 186 208 0.0074 T 10-03-2017 IPR003368 Polymorphic outer membrane protein repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Pfam PF02415 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat 230 245 0.057 T 10-03-2017 IPR003368 Polymorphic outer membrane protein repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 Gene3D G3DSA:2.160.20.20 490 932 2.5E-35 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 328 359 3.4E-8 T 10-03-2017 IPR013425 Autotransporter-associated beta strand repeat RG49_RS23950 41711b9790edd47c47a8d38750bbed4b 1250 SUPERFAMILY SSF103515 969 1250 4.05E-33 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS19245 362ca19ec97b6ac525bd34a13e2a82da 470 SUPERFAMILY SSF51556 3 465 1.77E-184 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS19245 362ca19ec97b6ac525bd34a13e2a82da 470 Pfam PF02614 Glucuronate isomerase 1 465 2.1E-230 T 10-03-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 RG49_RS19245 362ca19ec97b6ac525bd34a13e2a82da 470 Gene3D G3DSA:1.10.2020.10 46 137 3.1E-44 T 10-03-2017 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 RG49_RS19245 362ca19ec97b6ac525bd34a13e2a82da 470 Gene3D G3DSA:3.20.20.140 4 44 4.4E-166 T 10-03-2017 RG49_RS19245 362ca19ec97b6ac525bd34a13e2a82da 470 Gene3D G3DSA:3.20.20.140 139 466 4.4E-166 T 10-03-2017 RG49_RS19245 362ca19ec97b6ac525bd34a13e2a82da 470 Hamap MF_00675 Uronate isomerase [uxaC]. 2 467 50.676 T 10-03-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 RG49_RS23825 ca3c13477a20e356d3ec6c4cca81c8bc 322 Gene3D G3DSA:3.90.550.10 8 147 2.0E-25 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS23825 ca3c13477a20e356d3ec6c4cca81c8bc 322 Hamap MF_01164 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [arnC]. 2 322 60.869 T 10-03-2017 IPR022857 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase GO:0016780 KEGG: 00520+2.4.2.53 RG49_RS23825 ca3c13477a20e356d3ec6c4cca81c8bc 322 Pfam PF00535 Glycosyl transferase family 2 11 171 5.0E-34 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS23825 ca3c13477a20e356d3ec6c4cca81c8bc 322 SUPERFAMILY SSF53448 8 230 1.38E-37 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 Pfam PF06689 ClpX C4-type zinc finger 13 50 3.0E-21 T 10-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 5 412 3.7E-217 T 10-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 Pfam PF07724 AAA domain (Cdc48 subfamily) 112 310 9.3E-49 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 Gene3D G3DSA:1.10.8.60 316 413 2.1E-38 T 10-03-2017 RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 1.7E-17 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 SUPERFAMILY SSF52540 64 403 1.78E-73 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 SMART SM00382 111 333 1.3E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 SMART SM00994 12 51 1.0E-24 T 10-03-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 Gene3D G3DSA:3.40.50.300 66 253 6.5E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 Gene3D G3DSA:3.40.50.300 294 311 6.5E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 SUPERFAMILY SSF57716 13 48 5.84E-12 T 10-03-2017 RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 SMART SM01086 317 412 4.8E-36 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS08930 a012cfd0e4de441348271c672b888a8a 424 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 415 53.718 T 10-03-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 RG49_RS16100 4602cbd701a384e53b2fd82076422808 394 SUPERFAMILY SSF56349 98 380 1.24E-64 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS16100 4602cbd701a384e53b2fd82076422808 394 Gene3D G3DSA:1.10.150.130 98 193 1.1E-17 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS16100 4602cbd701a384e53b2fd82076422808 394 Gene3D G3DSA:1.10.443.10 206 375 1.5E-26 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS16100 4602cbd701a384e53b2fd82076422808 394 Pfam PF00589 Phage integrase family 206 370 3.7E-26 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS16100 4602cbd701a384e53b2fd82076422808 394 Pfam PF13356 Domain of unknown function (DUF4102) 3 88 4.5E-20 T 10-03-2017 IPR025166 Domain of unknown function DUF4102 RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 10-03-2017 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 Gene3D G3DSA:3.10.20.30 5 108 8.3E-37 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 6.5E-63 T 10-03-2017 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 92 6.1E-16 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 SUPERFAMILY SSF54292 4 109 7.9E-36 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 PRINTS PR00355 Adrenodoxin signature 42 52 1.2E-10 T 10-03-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 PRINTS PR00355 Adrenodoxin signature 60 74 1.2E-10 T 10-03-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 RG49_RS22445 65886732974b5f7a601190682a3b3ef5 111 PRINTS PR00355 Adrenodoxin signature 83 91 1.2E-10 T 10-03-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 Pfam PF03471 Transporter associated domain 347 425 2.2E-22 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 Pfam PF00571 CBS domain 284 333 0.0024 T 10-03-2017 IPR000644 CBS domain RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 SMART SM01091 346 426 4.6E-30 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 SUPERFAMILY SSF56176 344 428 4.91E-24 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 SUPERFAMILY SSF54631 200 335 1.89E-22 T 10-03-2017 RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 Pfam PF01595 Domain of unknown function DUF21 7 197 3.0E-38 T 10-03-2017 IPR002550 Domain of unknown function DUF21 RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 Gene3D G3DSA:3.30.465.10 342 425 1.1E-28 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS12790 5e17a86516a0e922489aad67242b433d 447 Gene3D G3DSA:3.10.580.10 198 334 1.2E-14 T 10-03-2017 RG49_RS22880 6dcf769c6e2ffab65759c3d1287bb666 338 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 17 319 2.3E-99 T 10-03-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS22880 6dcf769c6e2ffab65759c3d1287bb666 338 Pfam PF01515 Phosphate acetyl/butaryl transferase 1 320 1.6E-123 T 10-03-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS22880 6dcf769c6e2ffab65759c3d1287bb666 338 PIRSF PIRSF000428 1 326 1.9E-109 T 10-03-2017 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS22880 6dcf769c6e2ffab65759c3d1287bb666 338 SUPERFAMILY SSF53659 2 321 1.15E-82 T 10-03-2017 RG49_RS22880 6dcf769c6e2ffab65759c3d1287bb666 338 Gene3D G3DSA:3.40.50.10750 135 296 1.8E-63 T 10-03-2017 RG49_RS05290 a02cc5ce5986d9f93702d587a076bf74 97 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 90 1.1E-20 T 10-03-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 RG49_RS05290 a02cc5ce5986d9f93702d587a076bf74 97 Pfam PF04316 Anti-sigma-28 factor, FlgM 40 88 1.3E-9 T 10-03-2017 IPR031316 Anti-sigma-28 factor FlgM, C-terminal RG49_RS05290 a02cc5ce5986d9f93702d587a076bf74 97 SUPERFAMILY SSF101498 1 89 9.15E-13 T 10-03-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 RG49_RS07835 3cc1ce757a5dc289eb66afe0f13d0cf3 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 223 9.6E-18 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07835 3cc1ce757a5dc289eb66afe0f13d0cf3 224 Gene3D G3DSA:1.10.3720.10 13 223 9.5E-45 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07835 3cc1ce757a5dc289eb66afe0f13d0cf3 224 SUPERFAMILY SSF161098 14 210 3.4E-38 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07835 3cc1ce757a5dc289eb66afe0f13d0cf3 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 118 6.4E-24 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS02110 e3bc3c3c0834444c01aa17078c383459 231 SUPERFAMILY SSF52540 1 213 5.69E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02110 e3bc3c3c0834444c01aa17078c383459 231 Gene3D G3DSA:3.40.50.300 2 212 6.0E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02110 e3bc3c3c0834444c01aa17078c383459 231 PIRSF PIRSF006755 1 225 5.3E-63 T 10-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 RG49_RS02110 e3bc3c3c0834444c01aa17078c383459 231 Pfam PF13500 AAA domain 4 207 1.0E-28 T 10-03-2017 RG49_RS02110 e3bc3c3c0834444c01aa17078c383459 231 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 172 1.4E-39 T 10-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 RG49_RS02110 e3bc3c3c0834444c01aa17078c383459 231 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 220 23.964 T 10-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 RG49_RS13565 31c48e83617ae616d4965ba6ad2f4d39 309 Gene3D G3DSA:3.30.420.40 2 145 1.1E-22 T 10-03-2017 RG49_RS13565 31c48e83617ae616d4965ba6ad2f4d39 309 ProSitePatterns PS01125 ROK family signature. 139 166 - T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS13565 31c48e83617ae616d4965ba6ad2f4d39 309 Hamap MF_00988 D-allose kinase [alsK]. 1 301 69.658 T 10-03-2017 IPR030883 D-allose kinase GO:0019200|GO:0019316 KEGG: 00051+2.7.1.55 RG49_RS13565 31c48e83617ae616d4965ba6ad2f4d39 309 SUPERFAMILY SSF53067 8 301 8.3E-46 T 10-03-2017 RG49_RS13565 31c48e83617ae616d4965ba6ad2f4d39 309 Gene3D G3DSA:3.30.420.40 146 275 4.5E-34 T 10-03-2017 RG49_RS13565 31c48e83617ae616d4965ba6ad2f4d39 309 Pfam PF00480 ROK family 9 298 2.1E-96 T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 Gene3D G3DSA:1.20.59.10 3 83 2.0E-22 T 10-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 SMART SM00830 9 89 2.9E-30 T 10-03-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 Pfam PF01817 Chorismate mutase type II 9 86 1.3E-19 T 10-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 Gene3D G3DSA:1.10.3660.10 248 372 1.6E-58 T 10-03-2017 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 SUPERFAMILY SSF51735 91 238 1.46E-37 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 SUPERFAMILY SSF48600 4 88 4.03E-23 T 10-03-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 TIGRFAM TIGR01799 CM_T: chorismate mutase 5 87 2.3E-46 T 10-03-2017 IPR011277 Chorismate mutase, T-protein GO:0004106|GO:0005737|GO:0006571|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 Pfam PF02153 Prephenate dehydrogenase 137 344 6.9E-31 T 10-03-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 SUPERFAMILY SSF48179 241 366 2.04E-42 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 Gene3D G3DSA:3.40.50.720 84 247 6.8E-47 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22030 6cd6d53860acfb56bf017bb8bc68fc51 373 PIRSF PIRSF001499 1 373 6.9E-187 T 10-03-2017 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 RG49_RS12700 b46aae0668a6ea8340fbe6826d793e02 712 Pfam PF03477 ATP cone domain 4 89 1.9E-21 T 10-03-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 RG49_RS12700 b46aae0668a6ea8340fbe6826d793e02 712 Gene3D G3DSA:3.20.70.20 124 685 1.2E-189 T 10-03-2017 RG49_RS12700 b46aae0668a6ea8340fbe6826d793e02 712 SUPERFAMILY SSF51998 121 687 2.17E-200 T 10-03-2017 RG49_RS12700 b46aae0668a6ea8340fbe6826d793e02 712 ProSitePatterns PS00850 Glycine radical domain signature. 676 684 - T 10-03-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site RG49_RS12700 b46aae0668a6ea8340fbe6826d793e02 712 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 115 705 1.5E-213 T 10-03-2017 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 RG49_RS12700 b46aae0668a6ea8340fbe6826d793e02 712 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 116 705 4.8E-185 T 10-03-2017 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 RG49_RS08625 387f8d4713918680be5812f660828394 305 PRINTS PR00721 Stomatin signature 171 192 2.8E-27 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS08625 387f8d4713918680be5812f660828394 305 PRINTS PR00721 Stomatin signature 73 94 2.8E-27 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS08625 387f8d4713918680be5812f660828394 305 PRINTS PR00721 Stomatin signature 108 125 2.8E-27 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS08625 387f8d4713918680be5812f660828394 305 PRINTS PR00721 Stomatin signature 128 151 2.8E-27 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS08625 387f8d4713918680be5812f660828394 305 PRINTS PR00721 Stomatin signature 152 170 2.8E-27 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS08625 387f8d4713918680be5812f660828394 305 SUPERFAMILY SSF117892 49 183 2.22E-41 T 10-03-2017 IPR001107 Band 7 domain RG49_RS08625 387f8d4713918680be5812f660828394 305 Pfam PF01145 SPFH domain / Band 7 family 22 203 3.6E-34 T 10-03-2017 IPR001107 Band 7 domain RG49_RS08625 387f8d4713918680be5812f660828394 305 SMART SM00244 18 176 2.1E-60 T 10-03-2017 IPR001107 Band 7 domain RG49_RS08625 387f8d4713918680be5812f660828394 305 Pfam PF16200 C-terminal region of band_7 238 297 3.7E-7 T 10-03-2017 IPR032435 Band 7, C-terminal extension RG49_RS08625 387f8d4713918680be5812f660828394 305 ProSitePatterns PS01270 Band 7 protein family signature. 132 160 - T 10-03-2017 IPR018080 Band 7/stomatin-like, conserved site RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 4.3E-33 T 10-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 SUPERFAMILY SSF52540 23 255 1.06E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 3.8E-147 T 10-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 SUPERFAMILY SSF46785 260 333 3.59E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 331 1.0E-40 T 10-03-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 Gene3D G3DSA:1.10.10.10 260 330 1.4E-35 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 Gene3D G3DSA:3.40.50.300 23 178 2.9E-33 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 8 238 1.9E-115 T 10-03-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 SMART SM00382 54 181 1.3E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 Gene3D G3DSA:1.10.8.60 187 258 7.3E-33 T 10-03-2017 RG49_RS00620 b9e5f42886aa37d5e491b1818f86e0e6 336 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 336 184.752 T 10-03-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Gene3D G3DSA:3.40.50.300 149 238 3.0E-26 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Gene3D G3DSA:1.10.8.60 306 372 1.4E-23 T 10-03-2017 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 SUPERFAMILY SSF140990 378 571 7.19E-63 T 10-03-2017 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 SMART SM00382 189 299 9.0E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 10 574 30.928 T 10-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Pfam PF06480 FtsH Extracellular 11 94 1.7E-6 T 10-03-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Gene3D G3DSA:3.40.50.300 239 305 1.5E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 SUPERFAMILY SSF52540 147 367 1.16E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 242 296 7.8E-11 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 193 240 8.3E-13 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Gene3D G3DSA:3.40.50.300 434 477 1.3E-4 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 Pfam PF01434 Peptidase family M41 359 568 2.9E-65 T 10-03-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 RG49_RS10010 4b94642d7dfa055e3f86b91ab23ce629 575 ProSitePatterns PS00674 AAA-protein family signature. 267 285 - T 10-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 RG49_RS07140 76891e9770f456724899fa1fb35a5c07 225 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 216 30.55 T 10-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 RG49_RS07140 76891e9770f456724899fa1fb35a5c07 225 Gene3D G3DSA:3.40.50.300 3 214 1.0E-83 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07140 76891e9770f456724899fa1fb35a5c07 225 PIRSF PIRSF006755 1 225 6.7E-90 T 10-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 RG49_RS07140 76891e9770f456724899fa1fb35a5c07 225 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 176 9.9E-68 T 10-03-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 RG49_RS07140 76891e9770f456724899fa1fb35a5c07 225 Pfam PF13500 AAA domain 3 208 5.4E-40 T 10-03-2017 RG49_RS07140 76891e9770f456724899fa1fb35a5c07 225 SUPERFAMILY SSF52540 3 211 5.31E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04235 12eb535e586bf0ca4aa5e39931655a45 196 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 3 21 1.7E-6 T 10-03-2017 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 RG49_RS04235 12eb535e586bf0ca4aa5e39931655a45 196 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 28 196 4.4E-61 T 10-03-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 RG49_RS04235 12eb535e586bf0ca4aa5e39931655a45 196 PIRSF PIRSF015617 1 196 3.5E-70 T 10-03-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 RG49_RS04235 12eb535e586bf0ca4aa5e39931655a45 196 Gene3D G3DSA:3.40.50.300 3 196 2.6E-78 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04235 12eb535e586bf0ca4aa5e39931655a45 196 SUPERFAMILY SSF52540 7 196 1.78E-77 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04235 12eb535e586bf0ca4aa5e39931655a45 196 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 24 196 1.4E-85 T 10-03-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 SUPERFAMILY SSF52540 136 380 1.61E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 Gene3D G3DSA:1.10.8.60 309 385 7.7E-23 T 10-03-2017 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 Pfam PF00072 Response regulator receiver domain 9 117 4.7E-30 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 Gene3D G3DSA:1.10.10.60 390 437 8.0E-8 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 Pfam PF00158 Sigma-54 interaction domain 136 302 1.8E-71 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 SMART SM00382 156 299 7.4E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 SMART SM00448 6 117 3.8E-34 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 Gene3D G3DSA:3.40.50.2300 3 126 5.6E-37 T 10-03-2017 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 Gene3D G3DSA:3.40.50.300 134 307 7.7E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 SUPERFAMILY SSF52172 4 180 2.85E-43 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS22295 2ba542e0ba7f1a945aef8f93486ef43b 444 SUPERFAMILY SSF46689 387 437 3.17E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 426 610 2.0E-34 T 10-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Pfam PF10371 Domain of unknown function 626 678 6.0E-23 T 10-03-2017 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 1 1165 0.0 T 10-03-2017 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Gene3D G3DSA:4.10.780.10 628 668 7.9E-21 T 10-03-2017 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 SUPERFAMILY SSF54862 665 838 6.7E-23 T 10-03-2017 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 347 8.1E-16 T 10-03-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 689 700 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 745 756 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 SUPERFAMILY SSF52518 2 254 5.3E-71 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 SUPERFAMILY SSF52922 256 411 1.86E-43 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Gene3D G3DSA:3.40.50.920 255 413 3.8E-63 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 954 1066 2.5E-8 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Gene3D G3DSA:3.40.50.970 796 1166 2.2E-127 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Pfam PF13484 4Fe-4S double cluster binding domain 689 757 1.1E-9 T 10-03-2017 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Gene3D G3DSA:3.40.50.970 1 254 4.6E-110 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 SMART SM00890 622 679 4.1E-29 T 10-03-2017 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 PIRSF PIRSF000159 1 1174 0.0 T 10-03-2017 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 SUPERFAMILY SSF53323 419 668 6.54E-77 T 10-03-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Gene3D G3DSA:3.30.70.20 672 783 6.6E-21 T 10-03-2017 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 13 243 4.4E-81 T 10-03-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 Gene3D G3DSA:3.40.920.10 418 619 7.9E-79 T 10-03-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 RG49_RS03510 4c08cb22aa4b3f291db16312c2aff10c 1174 SUPERFAMILY SSF52518 794 1166 2.14E-118 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS25135 5d4ad086607d6ea2ee611ce9c87339f8 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.2E-12 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25135 5d4ad086607d6ea2ee611ce9c87339f8 309 Gene3D G3DSA:1.10.10.10 6 86 2.7E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS25135 5d4ad086607d6ea2ee611ce9c87339f8 309 Gene3D G3DSA:3.40.190.10 90 199 7.7E-16 T 10-03-2017 RG49_RS25135 5d4ad086607d6ea2ee611ce9c87339f8 309 Pfam PF03466 LysR substrate binding domain 89 290 4.8E-23 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS25135 5d4ad086607d6ea2ee611ce9c87339f8 309 SUPERFAMILY SSF53850 90 292 2.53E-25 T 10-03-2017 RG49_RS25135 5d4ad086607d6ea2ee611ce9c87339f8 309 SUPERFAMILY SSF46785 5 88 4.08E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 5.0E-22 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 Gene3D G3DSA:1.20.120.530 96 231 2.6E-25 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 SMART SM00345 12 71 1.7E-25 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 SMART SM00895 100 224 3.4E-20 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 Pfam PF07729 FCD domain 100 222 7.0E-23 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.4E-10 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.4E-10 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 Gene3D G3DSA:1.10.10.10 6 72 8.2E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 SUPERFAMILY SSF46785 6 75 2.02E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16385 ea9fc0943b77b21ed777b870e6597352 258 SUPERFAMILY SSF48008 98 230 1.23E-26 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 SUPERFAMILY SSF90123 4 299 1.7E-26 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 2 527 8.4E-111 T 10-03-2017 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 Gene3D G3DSA:1.20.1560.10 9 303 2.1E-20 T 10-03-2017 RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 SMART SM00382 348 526 2.7E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 Pfam PF00005 ABC transporter 341 477 1.3E-27 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 Pfam PF00664 ABC transporter transmembrane region 47 197 5.7E-6 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 SUPERFAMILY SSF52540 316 530 1.49E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24070 d768734562fb5c38d80f6175844e766e 547 Gene3D G3DSA:3.40.50.300 322 530 1.0E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01680 cc08b2c65cfb6a8eefda0965ca4220d2 239 Pfam PF13247 4Fe-4S dicluster domain 101 197 3.2E-22 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS01680 cc08b2c65cfb6a8eefda0965ca4220d2 239 SUPERFAMILY SSF54862 51 236 3.24E-52 T 10-03-2017 RG49_RS01680 cc08b2c65cfb6a8eefda0965ca4220d2 239 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 141 152 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01680 cc08b2c65cfb6a8eefda0965ca4220d2 239 Gene3D G3DSA:3.30.70.20 117 167 1.2E-24 T 10-03-2017 RG49_RS01680 cc08b2c65cfb6a8eefda0965ca4220d2 239 Gene3D G3DSA:3.30.70.20 168 204 2.7E-25 T 10-03-2017 RG49_RS01680 cc08b2c65cfb6a8eefda0965ca4220d2 239 Gene3D G3DSA:3.30.70.20 53 116 2.7E-25 T 10-03-2017 RG49_RS12875 278e8ffa71bf4900256afeadbcdbf684 513 SUPERFAMILY SSF100950 276 504 4.54E-59 T 10-03-2017 RG49_RS12875 278e8ffa71bf4900256afeadbcdbf684 513 SMART SM00882 4 242 9.1E-60 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS12875 278e8ffa71bf4900256afeadbcdbf684 513 Gene3D G3DSA:3.40.810.20 277 498 2.9E-59 T 10-03-2017 RG49_RS12875 278e8ffa71bf4900256afeadbcdbf684 513 PIRSF PIRSF000858 1 513 4.3E-194 T 10-03-2017 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 RG49_RS12875 278e8ffa71bf4900256afeadbcdbf684 513 SUPERFAMILY SSF100950 3 256 2.86E-81 T 10-03-2017 RG49_RS12875 278e8ffa71bf4900256afeadbcdbf684 513 Pfam PF01144 Coenzyme A transferase 5 241 2.4E-26 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS12875 278e8ffa71bf4900256afeadbcdbf684 513 Gene3D G3DSA:3.40.1080.10 2 241 3.1E-62 T 10-03-2017 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 Pfam PF02867 Ribonucleotide reductase, barrel domain 176 693 2.1E-141 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 Pfam PF08343 Ribonucleotide reductase N-terminal 16 97 1.6E-28 T 10-03-2017 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 15 714 0.0 T 10-03-2017 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 Gene3D G3DSA:3.20.70.20 108 297 7.5E-57 T 10-03-2017 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 Gene3D G3DSA:3.20.70.20 577 691 7.5E-57 T 10-03-2017 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 Gene3D G3DSA:3.20.70.20 350 513 7.5E-57 T 10-03-2017 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 99 171 5.9E-12 T 10-03-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 382 393 2.6E-33 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 465 487 2.6E-33 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 426 449 2.6E-33 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 493 516 2.6E-33 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 577 604 2.6E-33 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 251 270 2.6E-33 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 SUPERFAMILY SSF48168 13 174 6.8E-63 T 10-03-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 566 588 - T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 103 696 1.1E-157 T 10-03-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21715 28a385a028a7b942152e8ea7e8df980f 714 SUPERFAMILY SSF51998 175 698 1.65E-185 T 10-03-2017 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 Gene3D G3DSA:3.40.50.2300 118 251 1.2E-24 T 10-03-2017 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 SUPERFAMILY SSF46689 338 385 3.12E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 SMART SM00342 301 384 1.2E-30 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 Gene3D G3DSA:1.10.10.60 338 385 1.1E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 Pfam PF13377 Periplasmic binding protein-like domain 113 277 2.4E-37 T 10-03-2017 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 Gene3D G3DSA:3.40.50.2300 58 117 2.0E-5 T 10-03-2017 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 338 380 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 353 368 6.5E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 368 384 6.5E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 Pfam PF12833 Helix-turn-helix domain 309 384 2.6E-19 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 SUPERFAMILY SSF53822 10 298 7.79E-46 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 Gene3D G3DSA:1.10.10.60 283 335 2.4E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16605 00a82d6c6e0d7f1ab456ff684a37cabf 392 SUPERFAMILY SSF46689 284 333 3.86E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 752 0.0 T 10-03-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 PIRSF PIRSF000382 2 753 0.0 T 10-03-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 426 749 2.1E-163 T 10-03-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 SUPERFAMILY SSF51726 391 751 1.57E-120 T 10-03-2017 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 753 37.52 T 10-03-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 312 1.3E-125 T 10-03-2017 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 SUPERFAMILY SSF51726 5 389 1.7E-114 T 10-03-2017 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 Gene3D G3DSA:3.20.20.210 5 384 2.6E-151 T 10-03-2017 RG49_RS15045 eaaada09fde0a46f85958c91e4029379 753 Gene3D G3DSA:3.20.20.210 387 751 5.3E-136 T 10-03-2017 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 Gene3D G3DSA:3.30.450.20 20 114 1.1E-21 T 10-03-2017 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 114 5.4E-12 T 10-03-2017 IPR000014 PAS domain RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 Gene3D G3DSA:1.10.287.950 274 478 5.8E-53 T 10-03-2017 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 SUPERFAMILY SSF58104 233 505 6.67E-61 T 10-03-2017 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 319 503 2.3E-49 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 SMART SM00283 259 506 7.2E-92 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 SUPERFAMILY SSF55785 21 114 8.2E-25 T 10-03-2017 IPR000014 PAS domain RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 280 309 1.7E-40 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 434 463 1.7E-40 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 415 1.7E-40 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 357 384 1.7E-40 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 Pfam PF00672 HAMP domain 188 246 1.8E-7 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 SMART SM00086 80 121 2.8E-5 T 10-03-2017 IPR001610 PAC motif RG49_RS19360 30e4d3df452f39f6eb787eefa47371f1 506 Pfam PF08447 PAS fold 31 113 1.4E-16 T 10-03-2017 IPR013655 PAS fold-3 GO:0005515 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 100 4.0E-17 T 10-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 6.0E-31 T 10-03-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 SUPERFAMILY SSF48300 3 57 5.62E-16 T 10-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 25.446 T 10-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 8.4E-48 T 10-03-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 SUPERFAMILY SSF54736 50 121 3.49E-25 T 10-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like RG49_RS14160 951984a24105ceca351709a149fd5e19 121 Gene3D G3DSA:1.20.5.710 2 50 1.5E-22 T 10-03-2017 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 49 4.6E-15 T 10-03-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS14160 951984a24105ceca351709a149fd5e19 121 Gene3D G3DSA:3.30.1390.10 51 121 5.7E-34 T 10-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like RG49_RS14460 bae0a6006f69bf13be9030f5b7daca34 319 SUPERFAMILY SSF110997 244 314 3.66E-20 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS14460 bae0a6006f69bf13be9030f5b7daca34 319 TIGRFAM TIGR02223 ftsN: cell division protein FtsN 2 315 1.2E-115 T 10-03-2017 IPR011930 Cell division protein FtsN GO:0005515 RG49_RS14460 bae0a6006f69bf13be9030f5b7daca34 319 Hamap MF_02039 Cell division protein FtsN [ftsN]. 36 319 34.339 T 10-03-2017 IPR011930 Cell division protein FtsN GO:0005515 RG49_RS14460 bae0a6006f69bf13be9030f5b7daca34 319 Pfam PF05036 Sporulation related domain 246 313 1.3E-16 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS14460 bae0a6006f69bf13be9030f5b7daca34 319 Gene3D G3DSA:3.30.70.1070 241 316 3.6E-32 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 Gene3D G3DSA:3.30.230.10 217 329 5.4E-38 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 SMART SM01340 212 331 1.5E-54 T 10-03-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 612 25.893 T 10-03-2017 IPR020667 DNA mismatch repair protein, MutL GO:0006298 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 122 1.2E-12 T 10-03-2017 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 SUPERFAMILY SSF54211 191 331 4.17E-35 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 311 7.8E-108 T 10-03-2017 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 SMART SM00853 438 573 2.4E-18 T 10-03-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 SUPERFAMILY SSF118116 434 613 8.89E-44 T 10-03-2017 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 SUPERFAMILY SSF55874 1 201 1.44E-57 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 330 2.5E-35 T 10-03-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 Gene3D G3DSA:3.30.565.10 2 202 4.2E-78 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 10-03-2017 IPR014762 DNA mismatch repair, conserved site RG49_RS13065 cc0b2101ac2383888b6f2403b33495c2 615 Pfam PF08676 MutL C terminal dimerisation domain 435 563 5.8E-25 T 10-03-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 RG49_RS07495 6ff92f17130b878ee6fe391e9d5a02d0 62 Pfam PF00419 Fimbrial protein 5 62 4.8E-6 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS07495 6ff92f17130b878ee6fe391e9d5a02d0 62 SUPERFAMILY SSF49401 7 62 1.29E-7 T 10-03-2017 IPR008966 Adhesion domain RG49_RS07495 6ff92f17130b878ee6fe391e9d5a02d0 62 Gene3D G3DSA:2.60.40.1090 6 62 1.1E-8 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS17970 c25c5cdc75b23e024b013a0adda4365b 493 Gene3D G3DSA:3.40.50.300 219 486 4.6E-101 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17970 c25c5cdc75b23e024b013a0adda4365b 493 Pfam PF00437 Type II/IV secretion system protein 114 380 6.3E-89 T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS17970 c25c5cdc75b23e024b013a0adda4365b 493 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 308 322 - T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS17970 c25c5cdc75b23e024b013a0adda4365b 493 Gene3D G3DSA:3.30.450.90 85 213 3.7E-52 T 10-03-2017 RG49_RS17970 c25c5cdc75b23e024b013a0adda4365b 493 SUPERFAMILY SSF52540 94 484 1.64E-105 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17970 c25c5cdc75b23e024b013a0adda4365b 493 SMART SM00382 241 383 4.4E-6 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17970 c25c5cdc75b23e024b013a0adda4365b 493 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 25 484 5.2E-198 T 10-03-2017 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 109 136 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 361 379 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 320 345 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 252 271 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PRINTS PR00083 Histidinol dehydrogenase signature 230 251 3.5E-103 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 SUPERFAMILY SSF53720 6 429 1.75E-92 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 PIRSF PIRSF000099 1 430 9.6E-173 T 10-03-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 427 41.538 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 426 1.9E-162 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 Gene3D G3DSA:3.40.50.1980 29 240 1.8E-82 T 10-03-2017 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 Pfam PF00815 Histidinol dehydrogenase 28 427 6.4E-167 T 10-03-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS25100 f46690cf37f02772b1ad8174f1141906 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 230 262 - T 10-03-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 RG49_RS02710 927a260d0d34a99c9cc51cd1c7b31d24 110 SUPERFAMILY SSF47413 6 74 1.21E-13 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02710 927a260d0d34a99c9cc51cd1c7b31d24 110 Pfam PF12844 Helix-turn-helix domain 9 70 1.8E-10 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS02710 927a260d0d34a99c9cc51cd1c7b31d24 110 SMART SM00530 10 69 1.7E-10 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS02710 927a260d0d34a99c9cc51cd1c7b31d24 110 Gene3D G3DSA:1.10.260.40 3 76 1.3E-18 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 SUPERFAMILY SSF51905 2 315 2.39E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 Gene3D G3DSA:3.50.50.60 4 109 2.5E-35 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 3.4E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 314 1.1E-125 T 10-03-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 2.5E-78 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 4.3E-41 T 10-03-2017 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 4.3E-41 T 10-03-2017 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 4.3E-41 T 10-03-2017 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 4.3E-41 T 10-03-2017 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.3E-41 T 10-03-2017 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 10-03-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 RG49_RS06300 7adccd89b1dd7e60f54a814b65b92b41 321 Gene3D G3DSA:3.50.50.60 110 308 1.5E-35 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 SMART SM00388 249 317 3.5E-18 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 Gene3D G3DSA:1.10.287.130 241 313 4.9E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 Gene3D G3DSA:3.30.565.10 319 472 4.1E-32 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS22285 34ce7952dd9df10346223d565824e199 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 316 2.0E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 9.6E-11 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 9.6E-11 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 9.6E-11 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 9.6E-11 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 SUPERFAMILY SSF47384 236 316 8.83E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 SUPERFAMILY SSF55874 321 469 9.82E-31 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS22285 34ce7952dd9df10346223d565824e199 475 Pfam PF00672 HAMP domain 176 243 6.8E-8 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS22285 34ce7952dd9df10346223d565824e199 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 470 2.1E-15 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS22285 34ce7952dd9df10346223d565824e199 475 SMART SM00387 360 472 1.1E-25 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23905 e6c3ab221b2d15fd76c219765a11701e 358 Gene3D G3DSA:3.20.20.190 32 355 1.6E-95 T 10-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 RG49_RS23905 e6c3ab221b2d15fd76c219765a11701e 358 SUPERFAMILY SSF51695 32 356 3.4E-94 T 10-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 RG49_RS23905 e6c3ab221b2d15fd76c219765a11701e 358 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 36 350 7.0E-79 T 10-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 RG49_RS09565 b7184d1b2c80ac7e3018dee6126cbc49 310 SUPERFAMILY SSF53850 91 293 6.52E-18 T 10-03-2017 RG49_RS09565 b7184d1b2c80ac7e3018dee6126cbc49 310 Pfam PF03466 LysR substrate binding domain 91 280 6.2E-18 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS09565 b7184d1b2c80ac7e3018dee6126cbc49 310 SUPERFAMILY SSF46785 8 90 1.24E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09565 b7184d1b2c80ac7e3018dee6126cbc49 310 Gene3D G3DSA:3.40.190.10 110 205 6.8E-7 T 10-03-2017 RG49_RS09565 b7184d1b2c80ac7e3018dee6126cbc49 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 4.2E-17 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS09565 b7184d1b2c80ac7e3018dee6126cbc49 310 Gene3D G3DSA:1.10.10.10 9 89 2.9E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS18585 386e027e457f0b95276ef25a571eff4e 309 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 301 9.8E-143 T 10-03-2017 IPR005911 Protein YhcC-like GO:0051536 RG49_RS18585 386e027e457f0b95276ef25a571eff4e 309 SMART SM00729 23 247 1.3E-42 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS18585 386e027e457f0b95276ef25a571eff4e 309 Pfam PF16199 Radical_SAM C-terminal domain 208 283 2.9E-17 T 10-03-2017 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 RG49_RS18585 386e027e457f0b95276ef25a571eff4e 309 Pfam PF04055 Radical SAM superfamily 43 202 2.9E-15 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS18585 386e027e457f0b95276ef25a571eff4e 309 Gene3D G3DSA:3.80.30.20 22 231 5.4E-34 T 10-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe RG49_RS18585 386e027e457f0b95276ef25a571eff4e 309 SUPERFAMILY SSF102114 13 254 1.96E-45 T 10-03-2017 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 SMART SM01350 179 467 4.2E-221 T 10-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 174 3.3E-51 T 10-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 10-03-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 Gene3D G3DSA:1.10.1040.10 181 433 1.3E-118 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 466 1.7E-131 T 10-03-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 SUPERFAMILY SSF51735 4 173 4.86E-50 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 SUPERFAMILY SSF48179 177 467 8.16E-131 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 Gene3D G3DSA:3.40.50.720 1 180 1.9E-61 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 PIRSF PIRSF000109 1 468 1.8E-242 T 10-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 467 1.6E-231 T 10-03-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 Gene3D G3DSA:1.20.5.320 436 467 1.4E-22 T 10-03-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 1.5E-89 T 10-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 1.5E-89 T 10-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.5E-89 T 10-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.5E-89 T 10-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.5E-89 T 10-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS25055 051d22bcbfbd9f53b61ca0f200fe91f2 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 356 378 1.5E-89 T 10-03-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 RG49_RS08720 7c2f949d42783fbb757e42e7445e27a4 320 Hamap MF_00323 Ferrochelatase [hemH]. 4 320 38.508 T 10-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 RG49_RS08720 7c2f949d42783fbb757e42e7445e27a4 320 ProSitePatterns PS00534 Ferrochelatase signature. 189 207 - T 10-03-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 RG49_RS08720 7c2f949d42783fbb757e42e7445e27a4 320 SUPERFAMILY SSF53800 4 318 2.62E-101 T 10-03-2017 RG49_RS08720 7c2f949d42783fbb757e42e7445e27a4 320 Pfam PF00762 Ferrochelatase 5 317 6.2E-110 T 10-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 RG49_RS08720 7c2f949d42783fbb757e42e7445e27a4 320 Gene3D G3DSA:3.40.50.1400 202 317 2.7E-32 T 10-03-2017 RG49_RS08720 7c2f949d42783fbb757e42e7445e27a4 320 Gene3D G3DSA:3.40.50.1400 3 201 7.4E-68 T 10-03-2017 RG49_RS08720 7c2f949d42783fbb757e42e7445e27a4 320 TIGRFAM TIGR00109 hemH: ferrochelatase 1 319 3.9E-135 T 10-03-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 RG49_RS04155 3d0419be46807de4477a6f83c65792a1 245 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 68 81 - T 10-03-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS04155 3d0419be46807de4477a6f83c65792a1 245 SMART SM00934 16 237 6.5E-99 T 10-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS04155 3d0419be46807de4477a6f83c65792a1 245 Gene3D G3DSA:3.20.20.70 14 241 1.6E-88 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS04155 3d0419be46807de4477a6f83c65792a1 245 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 17 237 3.4E-55 T 10-03-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS04155 3d0419be46807de4477a6f83c65792a1 245 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 14 242 40.361 T 10-03-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS04155 3d0419be46807de4477a6f83c65792a1 245 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 15 237 1.5E-54 T 10-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS04155 3d0419be46807de4477a6f83c65792a1 245 SUPERFAMILY SSF51366 14 240 6.1E-79 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 10-03-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 Gene3D G3DSA:3.90.110.10 170 439 2.5E-85 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 1.9E-77 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 6.5E-52 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 6.5E-52 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 194 206 6.5E-52 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 6.5E-52 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 6.5E-52 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 6.5E-52 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 6.5E-52 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 SUPERFAMILY SSF56327 173 443 6.2E-79 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 SUPERFAMILY SSF51735 4 167 3.63E-56 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 199 415 9.1E-36 T 10-03-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 RG49_RS01330 7b798e9c79a7baac75f2b675ac983a44 450 Gene3D G3DSA:3.40.50.720 3 168 3.9E-72 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 8.2E-7 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 8.2E-7 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 8.2E-7 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 SUPERFAMILY SSF103190 76 177 2.9E-11 T 10-03-2017 IPR029151 Periplasmic sensor domain-like RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 Gene3D G3DSA:3.30.565.10 306 471 2.3E-36 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 SMART SM00388 255 320 2.2E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 319 1.3E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 SUPERFAMILY SSF55874 311 469 2.1E-34 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 Gene3D G3DSA:1.10.287.130 260 305 2.8E-9 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 SMART SM00304 204 255 4.4E-6 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 SUPERFAMILY SSF47384 241 320 1.53E-13 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 464 5.0E-16 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 Pfam PF00672 HAMP domain 185 251 2.3E-10 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS11910 51948a21732bf2dd0c6f4bc531c66381 474 SMART SM00387 363 473 6.5E-26 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 SUPERFAMILY SSF51064 139 195 1.83E-16 T 10-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 Pfam PF01025 GrpE 35 194 7.3E-47 T 10-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 ProSitePatterns PS01071 grpE protein signature. 149 192 - T 10-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 Gene3D G3DSA:2.30.22.10 138 196 7.3E-24 T 10-03-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 Gene3D G3DSA:3.90.20.20 34 137 1.6E-32 T 10-03-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 SUPERFAMILY SSF58014 42 138 1.57E-26 T 10-03-2017 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 Hamap MF_01151 Protein GrpE [grpE]. 4 194 20.664 T 10-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 PRINTS PR00773 GrpE protein signature 173 192 1.3E-25 T 10-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 PRINTS PR00773 GrpE protein signature 63 79 1.3E-25 T 10-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 PRINTS PR00773 GrpE protein signature 146 161 1.3E-25 T 10-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 RG49_RS21965 5e8dd7584f5b3f84803dfd5fe0a762c0 197 PRINTS PR00773 GrpE protein signature 91 106 1.3E-25 T 10-03-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 RG49_RS25075 5efa2c074e05b0c70cfb1f83c789005a 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 1.3E-118 T 10-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 RG49_RS25075 5efa2c074e05b0c70cfb1f83c789005a 258 Gene3D G3DSA:3.20.20.70 4 257 5.3E-89 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS25075 5efa2c074e05b0c70cfb1f83c789005a 258 Pfam PF00977 Histidine biosynthesis protein 5 239 4.4E-79 T 10-03-2017 IPR006062 Histidine biosynthesis GO:0000105 RG49_RS25075 5efa2c074e05b0c70cfb1f83c789005a 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 45.081 T 10-03-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 RG49_RS25075 5efa2c074e05b0c70cfb1f83c789005a 258 SUPERFAMILY SSF51366 1 257 1.33E-73 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS05960 bd691998ea3f9cfa35179f4cc74664a0 187 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 26 180 3.6E-40 T 10-03-2017 IPR005586 ABC-type transport auxiliary lipoprotein component RG49_RS05960 bd691998ea3f9cfa35179f4cc74664a0 187 SUPERFAMILY SSF159594 24 184 2.88E-28 T 10-03-2017 RG49_RS05960 bd691998ea3f9cfa35179f4cc74664a0 187 Gene3D G3DSA:3.40.50.10610 14 166 3.6E-14 T 10-03-2017 IPR005586 ABC-type transport auxiliary lipoprotein component RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 SUPERFAMILY SSF52540 5 226 6.79E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 Gene3D G3DSA:3.40.50.300 324 552 2.2E-68 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 Gene3D G3DSA:3.40.50.300 2 227 6.3E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 SUPERFAMILY SSF52540 324 549 4.35E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 Pfam PF00005 ABC transporter 26 165 6.8E-25 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 Pfam PF00005 ABC transporter 346 489 9.9E-29 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 SMART SM00382 354 535 6.2E-15 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS07060 cf1c3c05c2be617a98dc0eca8d54e14a 578 SMART SM00382 32 266 5.8E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 SUPERFAMILY SSF56228 3 210 2.22E-61 T 10-03-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 Gene3D G3DSA:1.10.599.10 443 687 2.9E-66 T 10-03-2017 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 Gene3D G3DSA:3.60.9.10 3 209 1.4E-79 T 10-03-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 SUPERFAMILY SSF48310 212 699 7.98E-78 T 10-03-2017 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 205 4.3E-67 T 10-03-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 Gene3D G3DSA:1.10.569.10 296 442 1.4E-5 T 10-03-2017 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 228 685 1.3E-69 T 10-03-2017 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 RG49_RS01670 b893d5f9bdf4b4af5330c485a2f3bb5a 700 SMART SM00790 5 206 6.6E-85 T 10-03-2017 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 RG49_RS02240 346a5cc710e01c2587eb79a3e6c8e552 141 Gene3D G3DSA:1.10.3600.10 1 122 1.3E-50 T 10-03-2017 IPR009364 Putative bacterial toxin ydaT RG49_RS02240 346a5cc710e01c2587eb79a3e6c8e552 141 Pfam PF06254 Putative bacterial toxin ydaT 48 101 3.6E-10 T 10-03-2017 IPR009364 Putative bacterial toxin ydaT RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 SUPERFAMILY SSF53807 34 291 4.32E-58 T 10-03-2017 RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 236 253 9.2E-59 T 10-03-2017 IPR008091 Ferrichrome-binding periplasmic protein RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 208 226 9.2E-59 T 10-03-2017 IPR008091 Ferrichrome-binding periplasmic protein RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 55 73 9.2E-59 T 10-03-2017 IPR008091 Ferrichrome-binding periplasmic protein RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 86 101 9.2E-59 T 10-03-2017 IPR008091 Ferrichrome-binding periplasmic protein RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 273 286 9.2E-59 T 10-03-2017 IPR008091 Ferrichrome-binding periplasmic protein RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 184 199 9.2E-59 T 10-03-2017 IPR008091 Ferrichrome-binding periplasmic protein RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 Pfam PF01497 Periplasmic binding protein 38 269 7.8E-27 T 10-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 Gene3D G3DSA:3.40.50.1980 124 294 2.4E-65 T 10-03-2017 RG49_RS11065 3dc6f035d807193f2faa8c058a64169a 296 Gene3D G3DSA:3.40.50.1980 34 120 1.2E-31 T 10-03-2017 RG49_RS04000 18dca3e93ec28bfdee59bd227ada733e 104 Gene3D G3DSA:3.40.250.10 23 96 3.7E-22 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS04000 18dca3e93ec28bfdee59bd227ada733e 104 SMART SM00450 7 103 1.3E-13 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS04000 18dca3e93ec28bfdee59bd227ada733e 104 Pfam PF00581 Rhodanese-like domain 22 89 3.8E-12 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS04000 18dca3e93ec28bfdee59bd227ada733e 104 SUPERFAMILY SSF52821 23 93 3.27E-19 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS04000 18dca3e93ec28bfdee59bd227ada733e 104 TIGRFAM TIGR02981 phageshock_pspE: phage shock operon rhodanese PspE 3 103 1.3E-63 T 10-03-2017 IPR014323 Phage shock protein, PspE KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 RG49_RS10315 2f2716dbbf63636576aaa1f7e89c2003 164 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 45 158 5.9E-22 T 10-03-2017 IPR006448 Putative phage terminase, small subunit, P27 family RG49_RS10315 2f2716dbbf63636576aaa1f7e89c2003 164 Pfam PF05119 Phage terminase, small subunit 58 146 3.1E-21 T 10-03-2017 IPR006448 Putative phage terminase, small subunit, P27 family RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 355 893 2.5E-148 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.30.365.10 811 955 2.5E-55 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.30.365.10 559 652 2.5E-55 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.30.365.10 653 810 1.1E-42 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 SMART SM01008 186 298 5.0E-36 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:1.10.150.120 73 175 8.8E-17 T 10-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.30.365.10 378 480 1.3E-36 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Pfam PF01799 [2Fe-2S] binding domain 73 144 1.1E-8 T 10-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 SUPERFAMILY SSF54665 164 317 2.49E-45 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 187 297 9.1E-31 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.30.365.10 483 558 1.2E-37 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.30.365.10 353 377 1.2E-37 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.30.365.10 299 317 1.2E-37 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 TIGRFAM TIGR03313 Se_sel_red_Mo: probable selenate reductase, molybdenum-binding subunit 5 955 0.0 T 10-03-2017 IPR017699 Molybdenum-binding protein YgfN/XdhD RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 SUPERFAMILY SSF47741 84 188 4.06E-17 T 10-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 SUPERFAMILY SSF56003 302 318 3.4E-166 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 SUPERFAMILY SSF56003 354 955 3.4E-166 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20500 da50bb64ff6ce12759911811979e4142 956 Gene3D G3DSA:3.90.1170.50 176 297 9.4E-36 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS09865 0e2ae6a78bfe082a381dc4681bbb317f 284 PIRSF PIRSF007319 34 281 2.4E-124 T 10-03-2017 IPR016513 Uncharacterised conserved protein UCP007319 RG49_RS19175 8a7deadc384129ada73c4d1e22f3408e 298 Gene3D G3DSA:1.10.10.10 7 92 3.1E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19175 8a7deadc384129ada73c4d1e22f3408e 298 SUPERFAMILY SSF53850 93 288 1.48E-23 T 10-03-2017 RG49_RS19175 8a7deadc384129ada73c4d1e22f3408e 298 SUPERFAMILY SSF46785 8 91 1.69E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19175 8a7deadc384129ada73c4d1e22f3408e 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 5.0E-16 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19175 8a7deadc384129ada73c4d1e22f3408e 298 Gene3D G3DSA:3.40.190.10 178 264 5.0E-10 T 10-03-2017 RG49_RS19175 8a7deadc384129ada73c4d1e22f3408e 298 Pfam PF03466 LysR substrate binding domain 96 280 2.5E-18 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS19175 8a7deadc384129ada73c4d1e22f3408e 298 Gene3D G3DSA:3.40.190.10 94 177 4.8E-9 T 10-03-2017 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Pfam PF03144 Elongation factor Tu domain 2 205 275 2.9E-12 T 10-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 308.566 T 10-03-2017 IPR006297 Elongation factor 4 GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Gene3D G3DSA:3.30.70.240 401 489 3.8E-20 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 SUPERFAMILY SSF54980 399 493 3.93E-24 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Gene3D G3DSA:3.30.70.870 291 369 7.8E-26 T 10-03-2017 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Gene3D G3DSA:3.40.50.300 2 192 9.3E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 TIGRFAM TIGR01393 lepA: elongation factor 4 2 594 4.2E-302 T 10-03-2017 IPR006297 Elongation factor 4 GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Pfam PF00009 Elongation factor Tu GTP binding domain 2 181 1.5E-52 T 10-03-2017 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Pfam PF06421 GTP-binding protein LepA C-terminus 487 592 8.3E-50 T 10-03-2017 IPR013842 GTP-binding protein LepA, C-terminal RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 172 2.1E-16 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Pfam PF00679 Elongation factor G C-terminus 399 482 3.6E-19 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 PRINTS PR00315 GTP-binding elongation factor signature 90 101 4.0E-14 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 PRINTS PR00315 GTP-binding elongation factor signature 126 135 4.0E-14 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 PRINTS PR00315 GTP-binding elongation factor signature 6 19 4.0E-14 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 PRINTS PR00315 GTP-binding elongation factor signature 74 84 4.0E-14 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 PRINTS PR00315 GTP-binding elongation factor signature 49 57 4.0E-14 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 SUPERFAMILY SSF54980 292 370 2.01E-18 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 Gene3D G3DSA:2.40.30.10 193 289 8.3E-26 T 10-03-2017 RG49_RS22195 7201463f2ac9afc8df98af3c39a9de8f 599 SUPERFAMILY SSF52540 2 235 4.65E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09100 91ce89c8c196f54ebdda1ef42dfb6aee 375 Gene3D G3DSA:3.20.20.105 1 367 9.2E-171 T 10-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 RG49_RS09100 91ce89c8c196f54ebdda1ef42dfb6aee 375 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 359 58.719 T 10-03-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 RG49_RS09100 91ce89c8c196f54ebdda1ef42dfb6aee 375 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 369 5.8E-182 T 10-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 RG49_RS09100 91ce89c8c196f54ebdda1ef42dfb6aee 375 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 369 1.7E-192 T 10-03-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 RG49_RS09100 91ce89c8c196f54ebdda1ef42dfb6aee 375 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 361 1.2E-93 T 10-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 RG49_RS09100 91ce89c8c196f54ebdda1ef42dfb6aee 375 SUPERFAMILY SSF51713 1 364 9.94E-164 T 10-03-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 RG49_RS04480 a0b2da53f49701b5a83386d556ba8ddd 225 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 225 1.9E-128 T 10-03-2017 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS04480 a0b2da53f49701b5a83386d556ba8ddd 225 SUPERFAMILY SSF103501 1 224 3.66E-71 T 10-03-2017 IPR023234 NarG-like domain RG49_RS04480 a0b2da53f49701b5a83386d556ba8ddd 225 Gene3D G3DSA:1.20.950.20 2 216 9.2E-72 T 10-03-2017 RG49_RS04480 a0b2da53f49701b5a83386d556ba8ddd 225 Pfam PF02665 Nitrate reductase gamma subunit 5 224 6.5E-80 T 10-03-2017 IPR023234 NarG-like domain RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 SUPERFAMILY SSF56420 3 164 1.02E-61 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 PIRSF PIRSF004749 1 168 3.4E-55 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 Hamap MF_00163 Peptide deformylase [def]. 2 162 32.054 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 PRINTS PR01576 Peptide deformylase signature 120 149 1.1E-38 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 PRINTS PR01576 Peptide deformylase signature 101 119 1.1E-38 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 PRINTS PR01576 Peptide deformylase signature 89 100 1.1E-38 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 PRINTS PR01576 Peptide deformylase signature 33 62 1.1E-38 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 1.9E-66 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 Pfam PF01327 Polypeptide deformylase 4 152 1.5E-50 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS18170 6edaccfd0cf997a74924ac8da9f6b01f 169 Gene3D G3DSA:3.90.45.10 5 165 1.7E-63 T 10-03-2017 IPR023635 Peptide deformylase RG49_RS14575 893a3274dc45ef91b256983a83c8b153 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 1.5E-21 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS14575 893a3274dc45ef91b256983a83c8b153 232 Pfam PF00072 Response regulator receiver domain 4 112 4.4E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS14575 893a3274dc45ef91b256983a83c8b153 232 SMART SM00448 2 111 1.2E-45 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS14575 893a3274dc45ef91b256983a83c8b153 232 SMART SM00862 152 228 9.7E-23 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS14575 893a3274dc45ef91b256983a83c8b153 232 Gene3D G3DSA:1.10.10.10 130 229 1.0E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14575 893a3274dc45ef91b256983a83c8b153 232 SUPERFAMILY SSF52172 2 188 9.11E-42 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS14575 893a3274dc45ef91b256983a83c8b153 232 Gene3D G3DSA:3.40.50.2300 2 126 3.6E-41 T 10-03-2017 RG49_RS01310 e50988174a047faa057f9a6d0fa0d53b 106 Gene3D G3DSA:3.40.50.270 1 103 1.7E-35 T 10-03-2017 RG49_RS01310 e50988174a047faa057f9a6d0fa0d53b 106 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 1 94 1.5E-34 T 10-03-2017 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 RG49_RS01310 e50988174a047faa057f9a6d0fa0d53b 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 94 8.6E-16 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS01310 e50988174a047faa057f9a6d0fa0d53b 106 SUPERFAMILY SSF52794 4 102 1.33E-32 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 Gene3D G3DSA:3.30.2090.10 181 275 3.6E-27 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 Gene3D G3DSA:3.30.2090.10 722 811 1.4E-28 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.0E-110 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82866 807 1030 7.59E-45 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82866 296 497 1.44E-47 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 Gene3D G3DSA:1.20.1640.10 292 506 7.1E-57 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82714 182 272 1.7E-21 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82693 566 672 4.39E-29 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 Gene3D G3DSA:3.30.70.1430 39 139 2.5E-34 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82693 138 182 1.46E-24 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82693 274 330 1.46E-24 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 Gene3D G3DSA:1.10.3850.10 815 1028 7.0E-57 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 Gene3D G3DSA:3.30.70.1430 568 672 4.2E-34 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82693 39 132 4.53E-27 T 10-03-2017 RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 SUPERFAMILY SSF82714 723 809 5.36E-23 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS22820 b3af4f8eb03286d70cd6574827af45a9 1037 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1034 0.0 T 10-03-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 RG49_RS06430 f07736405e77d34a5b38d7f3018c699a 107 SUPERFAMILY SSF117782 1 106 9.16E-39 T 10-03-2017 IPR002765 Uncharacterised protein family UPF0145 RG49_RS06430 f07736405e77d34a5b38d7f3018c699a 107 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 24.701 T 10-03-2017 IPR002765 Uncharacterised protein family UPF0145 RG49_RS06430 f07736405e77d34a5b38d7f3018c699a 107 Pfam PF01906 Putative heavy-metal-binding 1 104 2.2E-40 T 10-03-2017 IPR002765 Uncharacterised protein family UPF0145 RG49_RS06430 f07736405e77d34a5b38d7f3018c699a 107 Gene3D G3DSA:3.30.110.70 1 104 4.3E-39 T 10-03-2017 IPR002765 Uncharacterised protein family UPF0145 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 Pfam PF01306 LacY proton/sugar symporter 2 412 1.3E-205 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 SUPERFAMILY SSF103473 6 401 1.22E-47 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 315 334 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 214 242 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 103 125 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 145 163 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 260 281 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 284 310 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 68 97 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 PRINTS PR00174 LacY proton/sugar symporter family signature 346 366 2.3E-111 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 Gene3D G3DSA:1.20.1250.20 4 189 1.4E-38 T 10-03-2017 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 Gene3D G3DSA:1.20.1250.20 209 408 2.9E-44 T 10-03-2017 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 ProSitePatterns PS00897 LacY family proton/sugar symporters signature 2. 280 294 - T 10-03-2017 IPR018457 LacY/RafB permease family, conserved site GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 6 401 6.1E-209 T 10-03-2017 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 RG49_RS09420 49f5aab847431e5b9d173eb0199e3347 417 ProSitePatterns PS00896 LacY family proton/sugar symporters signature 1. 64 78 - T 10-03-2017 IPR018457 LacY/RafB permease family, conserved site GO:0006810|GO:0016020 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 SUPERFAMILY SSF53474 414 655 4.63E-44 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 507 537 - T 10-03-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 Gene3D G3DSA:2.130.10.120 73 407 1.9E-98 T 10-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 SUPERFAMILY SSF50993 2 408 4.71E-82 T 10-03-2017 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 3 403 8.4E-119 T 10-03-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 Gene3D G3DSA:3.40.50.1820 416 644 1.7E-35 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 500 519 2.7E-54 T 10-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 472 496 2.7E-54 T 10-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 446 464 2.7E-54 T 10-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 550 2.7E-54 T 10-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 606 628 2.7E-54 T 10-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 588 603 2.7E-54 T 10-03-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 RG49_RS00720 101a837b707ee2ee1d19df79df8e0336 686 Pfam PF00326 Prolyl oligopeptidase family 463 676 4.9E-69 T 10-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 RG49_RS18190 c715ab70f88875f74a13050cc771ae09 190 SUPERFAMILY SSF55821 4 187 2.72E-56 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS18190 c715ab70f88875f74a13050cc771ae09 190 Pfam PF01300 Telomere recombination 16 189 1.5E-41 T 10-03-2017 IPR006070 YrdC-like domain GO:0003725 RG49_RS18190 c715ab70f88875f74a13050cc771ae09 190 Gene3D G3DSA:3.90.870.10 3 190 2.5E-55 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS18190 c715ab70f88875f74a13050cc771ae09 190 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 7 188 41.089 T 10-03-2017 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 RG49_RS17630 017f000777a7dd995b34803290a407ec 412 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 355 388 - T 10-03-2017 IPR004845 Type II secretion system GspD, conserved site GO:0008565 RG49_RS17630 017f000777a7dd995b34803290a407ec 412 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 22 409 7.4E-134 T 10-03-2017 IPR013355 Type IV pilus secretin PilQ GO:0009297|GO:0009306 RG49_RS17630 017f000777a7dd995b34803290a407ec 412 Pfam PF03958 Bacterial type II/III secretion system short domain 120 178 2.4E-9 T 10-03-2017 IPR005644 NolW-like RG49_RS17630 017f000777a7dd995b34803290a407ec 412 PRINTS PR00811 Bacterial general secretion pathway protein D signature 374 392 5.2E-12 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17630 017f000777a7dd995b34803290a407ec 412 PRINTS PR00811 Bacterial general secretion pathway protein D signature 397 411 5.2E-12 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17630 017f000777a7dd995b34803290a407ec 412 PRINTS PR00811 Bacterial general secretion pathway protein D signature 246 270 5.2E-12 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17630 017f000777a7dd995b34803290a407ec 412 Pfam PF00263 Bacterial type II and III secretion system protein 250 409 4.9E-45 T 10-03-2017 IPR004846 Type II/III secretion system GO:0009306 RG49_RS17630 017f000777a7dd995b34803290a407ec 412 PRINTS PR01032 Gene IV protein signature 271 294 2.5E-8 T 10-03-2017 RG49_RS17630 017f000777a7dd995b34803290a407ec 412 PRINTS PR01032 Gene IV protein signature 230 253 2.5E-8 T 10-03-2017 RG49_RS17630 017f000777a7dd995b34803290a407ec 412 PRINTS PR01032 Gene IV protein signature 337 365 2.5E-8 T 10-03-2017 RG49_RS17630 017f000777a7dd995b34803290a407ec 412 SMART SM00965 46 94 5.0E-5 T 10-03-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 RG49_RS06010 a4f4dea78477e0cad4ffd10432617020 180 Pfam PF00419 Fimbrial protein 33 180 5.8E-13 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS06010 a4f4dea78477e0cad4ffd10432617020 180 SUPERFAMILY SSF49401 31 180 7.95E-30 T 10-03-2017 IPR008966 Adhesion domain RG49_RS06010 a4f4dea78477e0cad4ffd10432617020 180 Gene3D G3DSA:2.60.40.1090 31 180 1.4E-32 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 Gene3D G3DSA:3.20.20.70 385 444 3.0E-12 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 Gene3D G3DSA:3.20.20.70 275 350 3.0E-12 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 SUPERFAMILY SSF51011 586 665 7.91E-21 T 10-03-2017 RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 SUPERFAMILY SSF74650 1 247 4.71E-68 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 SUPERFAMILY SSF117125 666 772 7.19E-34 T 10-03-2017 RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 Pfam PF01055 Glycosyl hydrolases family 31 240 667 2.9E-118 T 10-03-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 Pfam PF13802 Galactose mutarotase-like 159 218 1.3E-15 T 10-03-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain RG49_RS16115 5ba7f255c5b0c6cd1ebd83ee03e130fe 772 SUPERFAMILY SSF51445 263 603 1.1E-89 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Gene3D G3DSA:2.170.170.11 136 262 2.6E-71 T 10-03-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Gene3D G3DSA:2.170.170.11 296 333 2.6E-71 T 10-03-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Gene3D G3DSA:3.20.20.360 89 135 2.3E-144 T 10-03-2017 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Gene3D G3DSA:3.20.20.360 334 588 2.3E-144 T 10-03-2017 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Gene3D G3DSA:3.20.20.360 264 294 2.3E-144 T 10-03-2017 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Hamap MF_00641 Malate synthase G [glcB]. 1 723 373.407 T 10-03-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 3 723 0.0 T 10-03-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Gene3D G3DSA:1.10.1860.10 1 87 1.5E-34 T 10-03-2017 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Pfam PF01274 Malate synthase 18 697 1.8E-199 T 10-03-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 SUPERFAMILY SSF51645 4 720 3.01E-293 T 10-03-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS19920 1461bb5c0af6c1a3aebae69669861fdd 723 Gene3D G3DSA:1.20.1220.12 590 722 1.1E-74 T 10-03-2017 RG49_RS03970 bd0e98425bc48d75d410637d99969836 262 Pfam PF01261 Xylose isomerase-like TIM barrel 19 219 5.3E-27 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS03970 bd0e98425bc48d75d410637d99969836 262 Gene3D G3DSA:3.20.20.150 1 260 5.0E-52 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS03970 bd0e98425bc48d75d410637d99969836 262 SUPERFAMILY SSF51658 1 260 1.52E-52 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 PRINTS PR00478 Phosphoribulokinase family signature 182 205 2.5E-29 T 10-03-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 PRINTS PR00478 Phosphoribulokinase family signature 126 144 2.5E-29 T 10-03-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 PRINTS PR00478 Phosphoribulokinase family signature 164 181 2.5E-29 T 10-03-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 PRINTS PR00478 Phosphoribulokinase family signature 12 29 2.5E-29 T 10-03-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 Gene3D G3DSA:3.40.50.300 1 288 1.1E-128 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 ProSitePatterns PS00567 Phosphoribulokinase signature. 164 177 - T 10-03-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 SUPERFAMILY SSF52540 4 286 1.84E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17820 d96b7e35e3d96f59c5fb9bfa13343bdb 289 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 2.1E-78 T 10-03-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 RG49_RS06370 c638f0eb1591de97e2a5d99f3d012df4 552 Pfam PF11398 Protein of unknown function (DUF2813) 1 375 1.6E-155 T 10-03-2017 IPR022602 Protein of unknown function DUF2813 RG49_RS06370 c638f0eb1591de97e2a5d99f3d012df4 552 SUPERFAMILY SSF52540 1 331 2.22E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06370 c638f0eb1591de97e2a5d99f3d012df4 552 Gene3D G3DSA:3.40.50.300 1 129 1.8E-21 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06370 c638f0eb1591de97e2a5d99f3d012df4 552 Gene3D G3DSA:3.40.50.300 165 343 1.8E-21 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20630 ee762863f3a1960ab09746e2eddb10f8 284 PRINTS PR01339 Type III secretion system outer membrane O protein family signature 209 221 8.8E-13 T 10-03-2017 IPR003283 Type III secretion system outer membrane, SpaO GO:0009306 RG49_RS20630 ee762863f3a1960ab09746e2eddb10f8 284 PRINTS PR01339 Type III secretion system outer membrane O protein family signature 136 146 8.8E-13 T 10-03-2017 IPR003283 Type III secretion system outer membrane, SpaO GO:0009306 RG49_RS20630 ee762863f3a1960ab09746e2eddb10f8 284 PRINTS PR01339 Type III secretion system outer membrane O protein family signature 253 270 8.8E-13 T 10-03-2017 IPR003283 Type III secretion system outer membrane, SpaO GO:0009306 RG49_RS20630 ee762863f3a1960ab09746e2eddb10f8 284 Gene3D G3DSA:2.30.330.10 196 283 1.4E-22 T 10-03-2017 RG49_RS20630 ee762863f3a1960ab09746e2eddb10f8 284 TIGRFAM TIGR02551 SpaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family 1 276 9.6E-58 T 10-03-2017 IPR013385 Type III secretion system apparatus protein YscQ/HrcQ/SpaO GO:0030254 RG49_RS20630 ee762863f3a1960ab09746e2eddb10f8 284 SUPERFAMILY SSF101801 203 282 3.92E-15 T 10-03-2017 IPR001543 Surface presentation of antigen (SpoA) RG49_RS20630 ee762863f3a1960ab09746e2eddb10f8 284 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 208 277 6.0E-12 T 10-03-2017 IPR001543 Surface presentation of antigen (SpoA) RG49_RS04035 4f2b74b12129cb227031eb5b97afe5b4 426 Gene3D G3DSA:3.50.50.60 171 252 2.2E-49 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04035 4f2b74b12129cb227031eb5b97afe5b4 426 Gene3D G3DSA:3.50.50.60 344 399 2.2E-49 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04035 4f2b74b12129cb227031eb5b97afe5b4 426 Gene3D G3DSA:3.50.50.60 17 118 2.2E-49 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04035 4f2b74b12129cb227031eb5b97afe5b4 426 SUPERFAMILY SSF51905 354 411 2.46E-44 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04035 4f2b74b12129cb227031eb5b97afe5b4 426 SUPERFAMILY SSF51905 27 252 2.46E-44 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS04035 4f2b74b12129cb227031eb5b97afe5b4 426 Pfam PF01266 FAD dependent oxidoreductase 29 381 1.6E-54 T 10-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 RG49_RS05275 18a635cda0910181c6ca37d44a0e261a 134 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 134 3.3E-52 T 10-03-2017 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 RG49_RS05275 18a635cda0910181c6ca37d44a0e261a 134 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 87 131 1.5E-12 T 10-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain RG49_RS05275 18a635cda0910181c6ca37d44a0e261a 134 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 10-03-2017 IPR019776 Flagellar basal body rod protein, conserved site RG49_RS05275 18a635cda0910181c6ca37d44a0e261a 134 Pfam PF00460 Flagella basal body rod protein 7 37 1.1E-10 T 10-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 3.4E-14 T 10-03-2017 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.4E-14 T 10-03-2017 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 3.4E-14 T 10-03-2017 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 3.4E-14 T 10-03-2017 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 Gene3D G3DSA:3.50.50.60 266 354 1.0E-38 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 Gene3D G3DSA:3.50.50.60 2 180 1.0E-38 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 292 305 - T 10-03-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 3 388 3.7E-143 T 10-03-2017 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 Pfam PF01494 FAD binding domain 2 336 5.7E-24 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 SUPERFAMILY SSF51905 2 175 1.85E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 SUPERFAMILY SSF51905 265 381 1.85E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20370 b37efa57b35604c2e4ae4ec5de1c9e88 392 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 3 387 1.6E-137 T 10-03-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 Gene3D G3DSA:3.40.50.2300 171 332 8.9E-63 T 10-03-2017 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 SMART SM00354 1 71 3.0E-37 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 SUPERFAMILY SSF47413 1 59 1.29E-16 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.4E-19 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 Hamap MF_01277 HTH-type transcriptional repressor PurR [purR]. 1 335 58.896 T 10-03-2017 IPR023588 Transcription regulator HTH, PurR GO:0006355 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 Gene3D G3DSA:1.10.260.40 2 60 7.9E-24 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 Gene3D G3DSA:3.40.50.2300 61 170 1.4E-33 T 10-03-2017 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 Pfam PF13377 Periplasmic binding protein-like domain 171 331 9.4E-41 T 10-03-2017 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.7E-5 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.7E-5 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 10-03-2017 RG49_RS01745 8772cb040f2b5d7253f583d2f328de82 341 SUPERFAMILY SSF53822 60 340 9.82E-95 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.8E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.8E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 Gene3D G3DSA:1.10.357.10 59 205 1.7E-19 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 6.4E-18 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 SUPERFAMILY SSF46689 2 65 1.9E-17 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 Gene3D G3DSA:1.10.10.60 2 58 3.9E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 202 1.5E-48 T 10-03-2017 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 SUPERFAMILY SSF48498 84 202 9.89E-17 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS18285 ff83f8698962c2398a776c26ab31a8ca 220 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 10-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 2.1E-68 T 10-03-2017 RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.2E-15 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.2E-15 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.2E-15 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.1E-50 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.1E-50 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.1E-50 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.1E-50 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.1E-50 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.1E-50 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 SUPERFAMILY SSF51735 4 243 1.14E-87 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 9.2E-6 T 10-03-2017 RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 Gene3D G3DSA:3.40.50.720 2 243 7.5E-90 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 1.2E-102 T 10-03-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS05180 c22a193608c9d8f2f5ee499e05b45f4b 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS06530 e4bcd424fc555ea63b87abe561988a52 125 Pfam PF11045 Putative inner membrane protein of Enterobacteriaceae 3 117 2.1E-46 T 10-03-2017 IPR020368 Uncharacterised protein family YbjM GO:0016021 RG49_RS06530 e4bcd424fc555ea63b87abe561988a52 125 ProDom PD079046 MEMBRANE INNER YBJM TRANSMEMBRANE 1 118 9.0E-61 T 10-03-2017 IPR020368 Uncharacterised protein family YbjM GO:0016021 RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.1E-22 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 SUPERFAMILY SSF46785 3 113 1.39E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 SUPERFAMILY SSF53850 89 296 4.5E-43 T 10-03-2017 RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 Gene3D G3DSA:3.40.190.10 92 177 5.7E-16 T 10-03-2017 RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 Pfam PF03466 LysR substrate binding domain 89 292 9.8E-46 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.1E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.1E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.1E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 Gene3D G3DSA:1.10.10.10 4 88 6.6E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23090 f0648d0531ada3da457da12529d932c4 308 Gene3D G3DSA:3.40.190.10 178 261 9.1E-19 T 10-03-2017 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 Gene3D G3DSA:3.40.50.740 108 181 1.4E-50 T 10-03-2017 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 Gene3D G3DSA:3.40.50.740 394 625 1.4E-50 T 10-03-2017 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 PIRSF PIRSF000144 1 759 0.0 T 10-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 Pfam PF00384 Molybdopterin oxidoreductase 108 469 5.7E-29 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 12 758 0.0 T 10-03-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 SUPERFAMILY SSF50692 641 758 1.42E-12 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 Gene3D G3DSA:2.40.40.20 641 757 3.3E-8 T 10-03-2017 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 Pfam PF01568 Molydopterin dinucleotide binding domain 642 751 4.9E-6 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 SUPERFAMILY SSF53706 46 625 1.83E-146 T 10-03-2017 RG49_RS02815 c3a401b2f91087c938d994a34af1dd9a 759 Gene3D G3DSA:3.40.228.10 182 393 5.4E-62 T 10-03-2017 RG49_RS13010 355b706ff4325d4dc11f810247702ba4 133 Pfam PF09938 Uncharacterized protein conserved in bacteria (DUF2170) 3 131 3.6E-43 T 10-03-2017 IPR019231 Protein of unknown function DUF2170 RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 279 45.206 T 10-03-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 276 6.1E-118 T 10-03-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 215 231 - T 10-03-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 Gene3D G3DSA:3.20.20.150 1 278 4.6E-122 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 10-03-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 Pfam PF01261 Xylose isomerase-like TIM barrel 21 239 6.6E-44 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 10-03-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 SMART SM00518 3 279 3.6E-146 T 10-03-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 RG49_RS24360 a6ae3b93949f7b83e1f48a1c29a8077d 285 SUPERFAMILY SSF51658 1 277 1.13E-104 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS20995 6911d5dcc89e27c39476656ce6d3744e 401 SUPERFAMILY SSF53383 5 397 2.93E-109 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS20995 6911d5dcc89e27c39476656ce6d3744e 401 Gene3D G3DSA:3.40.640.10 32 280 5.3E-78 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS20995 6911d5dcc89e27c39476656ce6d3744e 401 Pfam PF00266 Aminotransferase class-V 21 388 7.2E-142 T 10-03-2017 IPR000192 Aminotransferase class V domain RG49_RS20995 6911d5dcc89e27c39476656ce6d3744e 401 Gene3D G3DSA:3.90.1150.10 281 393 4.9E-19 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS20995 6911d5dcc89e27c39476656ce6d3744e 401 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 213 232 - T 10-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site RG49_RS20995 6911d5dcc89e27c39476656ce6d3744e 401 TIGRFAM TIGR03392 FeS_syn_CsdA: cysteine desulfurase, catalytic subunit CsdA 4 401 7.7E-233 T 10-03-2017 IPR022471 Cysteine desulphurase, catalytic subunit, CsdA GO:0016226|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 RG49_RS14005 b4533687dc33041752f74c1f6e8959bc 309 PIRSF PIRSF000450 1 308 2.7E-148 T 10-03-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 RG49_RS14005 b4533687dc33041752f74c1f6e8959bc 309 SUPERFAMILY SSF52317 17 297 2.25E-100 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS14005 b4533687dc33041752f74c1f6e8959bc 309 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 3.0E-149 T 10-03-2017 RG49_RS14005 b4533687dc33041752f74c1f6e8959bc 309 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 302 3.7E-169 T 10-03-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 RG49_RS14005 b4533687dc33041752f74c1f6e8959bc 309 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 53.521 T 10-03-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 RG49_RS14005 b4533687dc33041752f74c1f6e8959bc 309 Pfam PF04204 Homoserine O-succinyltransferase 2 299 1.1E-131 T 10-03-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 RG49_RS14005 b4533687dc33041752f74c1f6e8959bc 309 Gene3D G3DSA:3.40.50.880 34 301 2.5E-122 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 1.3E-49 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 1.3E-49 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 1.3E-49 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 1.3E-49 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 1.3E-49 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 SUPERFAMILY SSF53850 5 219 6.29E-86 T 10-03-2017 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 297 40.357 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 297 1.2E-112 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 Gene3D G3DSA:3.30.160.40 221 306 2.1E-30 T 10-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 213 2.1E-78 T 10-03-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 296 2.0E-25 T 10-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 Gene3D G3DSA:3.40.190.10 3 110 2.7E-48 T 10-03-2017 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 SUPERFAMILY SSF54782 220 308 1.7E-29 T 10-03-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 231 247 - T 10-03-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 Gene3D G3DSA:3.40.190.10 111 199 5.9E-40 T 10-03-2017 RG49_RS15175 e821f2f40f67955d52f2418a6c928b16 313 PIRSF PIRSF001438 1 311 2.6E-123 T 10-03-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS00550 86d2ea6dbe7c239d3ab17863238082b7 366 PIRSF PIRSF000014 1 366 6.6E-156 T 10-03-2017 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 RG49_RS00550 86d2ea6dbe7c239d3ab17863238082b7 366 Gene3D G3DSA:1.10.3820.10 312 318 6.9E-27 T 10-03-2017 RG49_RS00550 86d2ea6dbe7c239d3ab17863238082b7 366 Gene3D G3DSA:1.10.3820.10 5 176 6.9E-27 T 10-03-2017 RG49_RS00550 86d2ea6dbe7c239d3ab17863238082b7 366 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 6 174 4.2E-66 T 10-03-2017 IPR005126 NapC/NirT cytochrome c, N-terminal RG49_RS00550 86d2ea6dbe7c239d3ab17863238082b7 366 SUPERFAMILY SSF48695 18 179 3.12E-47 T 10-03-2017 IPR011031 Multihaem cytochrome RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.9E-6 T 10-03-2017 RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 5.9E-6 T 10-03-2017 RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 SUPERFAMILY SSF51905 283 392 1.37E-43 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 SUPERFAMILY SSF51905 2 182 1.37E-43 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 SUPERFAMILY SSF54373 180 283 1.88E-24 T 10-03-2017 RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 Gene3D G3DSA:3.50.50.60 294 371 2.1E-37 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 Gene3D G3DSA:3.50.50.60 5 175 2.1E-37 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS01525 46bf11d88c09549eeb465a498abb02b9 429 Pfam PF01494 FAD binding domain 6 183 6.6E-13 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 Gene3D G3DSA:3.40.228.10 152 261 7.6E-72 T 10-03-2017 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 Gene3D G3DSA:3.40.228.10 1 108 7.6E-72 T 10-03-2017 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 Pfam PF00384 Molybdopterin oxidoreductase 2 378 1.1E-20 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 Pfam PF01568 Molydopterin dinucleotide binding domain 682 797 3.4E-16 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 716 743 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 SUPERFAMILY SSF53706 1 639 3.8E-231 T 10-03-2017 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 Gene3D G3DSA:2.40.40.20 605 804 8.5E-49 T 10-03-2017 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 803 0.0 T 10-03-2017 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 SUPERFAMILY SSF50692 675 804 2.07E-42 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 SUPERFAMILY SSF50692 624 648 2.07E-42 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS14695 27e528a36cbc19fd8fb8fa89a470dff9 804 Gene3D G3DSA:3.40.50.740 320 470 5.6E-58 T 10-03-2017 RG49_RS03365 f5c6f93beed5caed2e31c09f11f7a653 201 Gene3D G3DSA:3.40.50.360 1 199 1.6E-68 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS03365 f5c6f93beed5caed2e31c09f11f7a653 201 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 199 32.818 T 10-03-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 RG49_RS03365 f5c6f93beed5caed2e31c09f11f7a653 201 Pfam PF02525 Flavodoxin-like fold 3 195 1.7E-47 T 10-03-2017 IPR003680 Flavodoxin-like fold RG49_RS03365 f5c6f93beed5caed2e31c09f11f7a653 201 SUPERFAMILY SSF52218 1 199 9.56E-60 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 Pfam PF00271 Helicase conserved C-terminal domain 237 339 6.7E-26 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 Gene3D G3DSA:3.40.50.300 1 213 2.3E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 450 52.618 T 10-03-2017 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 SMART SM00490 259 340 7.6E-32 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 10-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 SMART SM00487 20 223 9.1E-64 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 Pfam PF00270 DEAD/DEAH box helicase 25 196 3.1E-51 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 Gene3D G3DSA:3.40.50.300 214 372 1.9E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07045 c5aa0875f61949b2219c54d035af0ee4 454 SUPERFAMILY SSF52540 75 361 4.7E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 SUPERFAMILY SSF102114 5 290 1.57E-71 T 10-03-2017 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 329 2.9E-111 T 10-03-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 Pfam PF13353 4Fe-4S single cluster domain 23 125 3.9E-7 T 10-03-2017 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 312 9.6E-40 T 10-03-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 5 329 38.01 T 10-03-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 10-03-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 SMART SM00729 14 222 9.8E-6 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 Pfam PF04055 Radical SAM superfamily 19 181 1.2E-28 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS07125 ef68617285a069cddfb16ece5db509ab 329 Gene3D G3DSA:3.20.20.70 3 303 4.4E-73 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 SMART SM01185 69 125 1.4E-13 T 10-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 Gene3D G3DSA:2.40.50.140 132 189 1.1E-22 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 SUPERFAMILY SSF50249 67 130 2.27E-11 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 PIRSF PIRSF005901 1 190 1.4E-59 T 10-03-2017 IPR020599 Translation elongation factor P/YeiP RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 Gene3D G3DSA:2.30.30.30 1 65 7.0E-16 T 10-03-2017 IPR014722 Ribosomal protein L2 domain 2 RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 Pfam PF01132 Elongation factor P (EF-P) OB domain 72 124 1.7E-13 T 10-03-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 SUPERFAMILY SSF50104 1 65 2.71E-11 T 10-03-2017 IPR008991 Translation protein SH3-like domain RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 SUPERFAMILY SSF50249 132 189 6.68E-15 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 TIGRFAM TIGR02178 yeiP: elongation factor P-like protein YeiP 3 189 6.9E-103 T 10-03-2017 IPR011897 Translation elongation factor P-like, YeiP RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 62 7.0E-17 T 10-03-2017 IPR013185 Translation elongation factor, KOW-like RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 Pfam PF09285 Elongation factor P, C-terminal 133 188 1.4E-18 T 10-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 ProSitePatterns PS01275 Elongation factor P signature. 154 173 - T 10-03-2017 IPR013852 Translation elongation factor P/YeiP, conserved site RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 SMART SM00841 133 188 1.7E-26 T 10-03-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 Gene3D G3DSA:2.40.50.140 67 131 2.4E-14 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS24295 d0f6208c7ec49867d6a18499e56be373 190 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 189 45.611 T 10-03-2017 IPR011897 Translation elongation factor P-like, YeiP RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 174 189 - T 10-03-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 SMART SM00928 336 381 4.3E-22 T 10-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 SUPERFAMILY SSF142984 248 330 1.44E-20 T 10-03-2017 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 349 360 - T 10-03-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 421 2.8E-26 T 10-03-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 SUPERFAMILY SSF140490 333 429 4.84E-32 T 10-03-2017 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 13 423 6.5E-205 T 10-03-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 SUPERFAMILY SSF142019 16 246 1.83E-85 T 10-03-2017 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 Pfam PF10531 SLBB domain 253 295 1.5E-6 T 10-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23670 8e3a7a12de0eea1970dd81e9f4ab2ff7 445 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 54 226 1.3E-49 T 10-03-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21295 8984a389be07dfe080021954688f88ae 307 Pfam PF01867 CRISPR associated protein Cas1 132 238 1.3E-9 T 10-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 RG49_RS21295 8984a389be07dfe080021954688f88ae 307 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 8 272 4.8E-115 T 10-03-2017 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 RG49_RS21295 8984a389be07dfe080021954688f88ae 307 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 14 289 16.956 T 10-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 RG49_RS21295 8984a389be07dfe080021954688f88ae 307 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 16 127 1.7E-21 T 10-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 RG49_RS21295 8984a389be07dfe080021954688f88ae 307 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 133 239 7.8E-31 T 10-03-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 ProSitePatterns PS00501 Signal peptidases I serine active site. 89 96 - T 10-03-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 ProSitePatterns PS00760 Signal peptidases I lysine active site. 146 158 - T 10-03-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 Gene3D G3DSA:2.170.230.10 155 263 8.8E-49 T 10-03-2017 IPR019766 Peptidase S26A, all-beta subdomain RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 Pfam PF00717 Peptidase S24-like 86 160 1.2E-20 T 10-03-2017 IPR019759 Peptidase S24/S26A/S26B RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 Gene3D G3DSA:2.10.109.10 264 309 7.5E-57 T 10-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 Gene3D G3DSA:2.10.109.10 76 154 7.5E-57 T 10-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 ProSitePatterns PS00761 Signal peptidases I signature 3. 269 282 - T 10-03-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 Pfam PF10502 Signal peptidase, peptidase S26 261 302 2.5E-7 T 10-03-2017 IPR019533 Peptidase S26 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 66 305 4.1E-43 T 10-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 SUPERFAMILY SSF51306 78 323 1.92E-84 T 10-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 144 156 2.9E-25 T 10-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 80 96 2.9E-25 T 10-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 RG49_RS22200 90522cfe810e9d803f7139007dd292c4 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 264 283 2.9E-25 T 10-03-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 RG49_RS04945 4e6e1f2c92b74c80f3c96875aaa8c43f 213 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 205 9.0E-110 T 10-03-2017 IPR007451 Uncharacterised protein family UPF0274 RG49_RS04945 4e6e1f2c92b74c80f3c96875aaa8c43f 213 Pfam PF04356 Protein of unknown function (DUF489) 7 199 2.2E-75 T 10-03-2017 IPR007451 Uncharacterised protein family UPF0274 RG49_RS04945 4e6e1f2c92b74c80f3c96875aaa8c43f 213 SUPERFAMILY SSF101322 2 210 1.96E-82 T 10-03-2017 IPR007451 Uncharacterised protein family UPF0274 RG49_RS04945 4e6e1f2c92b74c80f3c96875aaa8c43f 213 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 207 36.567 T 10-03-2017 IPR007451 Uncharacterised protein family UPF0274 RG49_RS04945 4e6e1f2c92b74c80f3c96875aaa8c43f 213 Gene3D G3DSA:1.10.3890.10 2 209 5.1E-89 T 10-03-2017 IPR007451 Uncharacterised protein family UPF0274 RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 Gene3D G3DSA:3.40.50.970 2 173 8.6E-74 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 Gene3D G3DSA:3.40.50.1220 190 357 4.5E-69 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 SUPERFAMILY SSF52518 2 179 9.51E-64 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 569 1.0E-285 T 10-03-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 SUPERFAMILY SSF52467 189 362 3.11E-63 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 431 450 - T 10-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 545 3.1E-49 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 Gene3D G3DSA:3.40.50.970 358 558 1.9E-76 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 SUPERFAMILY SSF52518 371 567 1.2E-68 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 168 6.3E-58 T 10-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 RG49_RS11475 5f12a997f27fae555456c91ae1fff791 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 2.2E-46 T 10-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 RG49_RS01625 da2b32a69f3473a0ec4e7cf05f85781c 248 SMART SM00382 26 223 8.4E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS01625 da2b32a69f3473a0ec4e7cf05f85781c 248 Pfam PF00005 ABC transporter 17 172 1.5E-19 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS01625 da2b32a69f3473a0ec4e7cf05f85781c 248 Gene3D G3DSA:3.40.50.300 1 236 1.7E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01625 da2b32a69f3473a0ec4e7cf05f85781c 248 SUPERFAMILY SSF52540 2 231 3.51E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01625 da2b32a69f3473a0ec4e7cf05f85781c 248 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS01625 da2b32a69f3473a0ec4e7cf05f85781c 248 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 1.6E-114 T 10-03-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 2.9E-284 T 10-03-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 Gene3D G3DSA:3.30.499.10 2 158 1.0E-23 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 10-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 10-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 286 300 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 82 95 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 119 132 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 195 208 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 343 354 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 399 412 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 209 222 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 133 148 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 PRINTS PR00415 Aconitase family signature 108 116 3.5E-51 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 62.924 T 10-03-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 1.1E-156 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 SUPERFAMILY SSF53732 2 464 3.27E-168 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 Gene3D G3DSA:3.40.1060.10 166 279 5.6E-40 T 10-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS11500 8b05df8dd18cbed13db57171c79931b8 466 Gene3D G3DSA:3.30.499.10 322 465 4.8E-63 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 326 38.955 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 SUPERFAMILY SSF51735 8 182 4.4E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 Gene3D G3DSA:1.10.1040.10 184 330 2.3E-58 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 SUPERFAMILY SSF48179 184 335 8.16E-58 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 PIRSF PIRSF000114 1 336 1.8E-101 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 Gene3D G3DSA:3.40.50.720 9 182 6.7E-58 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 323 1.4E-52 T 10-03-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 8.7E-42 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 8.7E-42 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 8.7E-42 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 8.7E-42 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 177 201 8.7E-42 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 242 259 8.7E-42 T 10-03-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS16365 1a8711b9d137a136af7ca5a23ee78b64 339 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 163 5.9E-52 T 10-03-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 8 280 8.1E-134 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 4 280 46.408 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 Pfam PF01842 ACT domain 8 69 5.6E-8 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 SUPERFAMILY SSF55021 6 67 4.0E-9 T 10-03-2017 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 PIRSF PIRSF036480 4 280 1.7E-114 T 10-03-2017 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 41 53 4.4E-70 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 86 108 4.4E-70 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 254 279 4.4E-70 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 9 35 4.4E-70 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 232 254 4.4E-70 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 108 135 4.4E-70 T 10-03-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 Pfam PF00551 Formyl transferase 86 262 3.5E-56 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 Gene3D G3DSA:3.40.50.170 85 276 2.0E-57 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 SUPERFAMILY SSF53328 86 279 8.9E-61 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS04445 e20825855d949f703ae9f801d1264938 280 Gene3D G3DSA:3.30.70.260 6 71 4.2E-12 T 10-03-2017 RG49_RS22220 42389b66c69d4b6314aab19100d429a3 242 Hamap MF_00201 DNA repair protein RecO [recO]. 1 231 23.143 T 10-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 RG49_RS22220 42389b66c69d4b6314aab19100d429a3 242 SUPERFAMILY SSF57863 86 165 2.59E-7 T 10-03-2017 RG49_RS22220 42389b66c69d4b6314aab19100d429a3 242 Gene3D G3DSA:2.40.50.140 6 75 7.4E-10 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS22220 42389b66c69d4b6314aab19100d429a3 242 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 230 1.1E-37 T 10-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 RG49_RS22220 42389b66c69d4b6314aab19100d429a3 242 Pfam PF11967 Recombination protein O N terminal 4 76 1.3E-22 T 10-03-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal RG49_RS22220 42389b66c69d4b6314aab19100d429a3 242 Pfam PF02565 Recombination protein O C terminal 83 226 4.8E-23 T 10-03-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 RG49_RS22220 42389b66c69d4b6314aab19100d429a3 242 SUPERFAMILY SSF50249 4 75 3.43E-14 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 Pfam PF00849 RNA pseudouridylate synthase 101 249 1.3E-29 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 SUPERFAMILY SSF55174 19 70 4.56E-9 T 10-03-2017 RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 Pfam PF01479 S4 domain 20 66 1.7E-10 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 316 1.3E-101 T 10-03-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 Gene3D G3DSA:3.10.290.10 20 68 1.5E-7 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 SUPERFAMILY SSF55120 95 316 1.76E-67 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 140 154 - T 10-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS05215 3a515f0a14370df3c1280722b9a64586 319 SMART SM00363 20 79 9.9E-10 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 Pfam PF01479 S4 domain 1 45 2.9E-9 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 224 8.1E-61 T 10-03-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 SUPERFAMILY SSF55120 61 227 1.23E-47 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 SMART SM00363 1 60 4.2E-11 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 10-03-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 Gene3D G3DSA:3.10.290.10 1 64 2.1E-22 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 SUPERFAMILY SSF55174 1 55 1.62E-12 T 10-03-2017 RG49_RS24230 fa03fcb61a8edc1b5b91fad4d162279e 231 Pfam PF00849 RNA pseudouridylate synthase 62 192 9.7E-18 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS03225 e2b541f9c8097bb9eceabc94cdab3c45 76 ProDom PD057831 YNCJ PRECURSOR SIGNAL PERIPLASMIC STY1461 1 76 3.0E-39 T 10-03-2017 IPR020117 Uncharacterised protein family YncJ RG49_RS03225 e2b541f9c8097bb9eceabc94cdab3c45 76 Pfam PF10829 Protein of unknown function (DUF2554) 1 76 4.7E-53 T 10-03-2017 IPR020117 Uncharacterised protein family YncJ RG49_RS06130 ae2794a89131c536e6628a86d1019515 261 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 2 255 43.968 T 10-03-2017 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 RG49_RS06130 ae2794a89131c536e6628a86d1019515 261 Gene3D G3DSA:3.40.50.150 5 243 4.2E-38 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06130 ae2794a89131c536e6628a86d1019515 261 SUPERFAMILY SSF53335 6 241 1.02E-42 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06130 ae2794a89131c536e6628a86d1019515 261 Pfam PF13847 Methyltransferase domain 45 151 1.2E-18 T 10-03-2017 IPR025714 Methyltransferase domain RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 SUPERFAMILY SSF53187 300 329 1.77E-58 T 10-03-2017 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 SUPERFAMILY SSF53187 384 448 1.77E-58 T 10-03-2017 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 SUPERFAMILY SSF53187 7 200 1.77E-58 T 10-03-2017 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 433 9.0E-134 T 10-03-2017 IPR017439 Amidohydrolase GO:0016787 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 Pfam PF01546 Peptidase family M20/M25/M40 80 173 1.4E-5 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 PIRSF PIRSF037227 1 481 1.3E-239 T 10-03-2017 IPR017145 Aminobenzoyl-glutamate utilization protein B RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 SUPERFAMILY SSF55031 191 293 1.44E-17 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 Gene3D G3DSA:3.40.630.10 2 185 3.1E-64 T 10-03-2017 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 Gene3D G3DSA:3.40.630.10 297 329 3.1E-64 T 10-03-2017 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 Gene3D G3DSA:3.40.630.10 384 460 3.1E-64 T 10-03-2017 RG49_RS03845 14e385cdd28401316d3cedefd16b2ded 481 Gene3D G3DSA:3.30.70.360 191 294 6.9E-19 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 SUPERFAMILY SSF82679 6 116 2.49E-40 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 Gene3D G3DSA:2.30.30.30 120 181 1.7E-32 T 10-03-2017 IPR014722 Ribosomal protein L2 domain 2 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 SMART SM00739 127 154 7.9E-7 T 10-03-2017 IPR005824 KOW RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 Pfam PF02357 Transcription termination factor nusG 7 112 1.8E-27 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 Pfam PF00467 KOW motif 130 162 4.2E-8 T 10-03-2017 IPR005824 KOW RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 Gene3D G3DSA:3.30.70.940 6 116 4.3E-43 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 180 5.7E-72 T 10-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 181 25.014 T 10-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 ProSitePatterns PS01014 Transcription termination factor nusG signature. 164 173 - T 10-03-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 SUPERFAMILY SSF50104 125 180 4.66E-20 T 10-03-2017 IPR008991 Translation protein SH3-like domain RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 1.9E-21 T 10-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 PRINTS PR00338 Transcription termination factor NUSG signature 139 154 1.9E-21 T 10-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 PRINTS PR00338 Transcription termination factor NUSG signature 157 173 1.9E-21 T 10-03-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 RG49_RS14185 b5d2ac662405ed8122bc520d5bb79ca1 181 SMART SM00738 6 115 5.9E-51 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 204 5.4E-88 T 10-03-2017 IPR015796 Impact family, bacterial/archaeal RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 8.1E-15 T 10-03-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 Gene3D G3DSA:3.30.70.240 135 204 7.2E-33 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 Pfam PF01205 Uncharacterized protein family UPF0029 18 125 2.2E-26 T 10-03-2017 IPR001498 Impact, N-terminal RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 80 109 - T 10-03-2017 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 SUPERFAMILY SSF54980 136 203 1.04E-18 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 Gene3D G3DSA:3.30.230.30 6 131 3.1E-43 T 10-03-2017 IPR001498 Impact, N-terminal RG49_RS14950 cc7745a3c3d033ec4e74cc9d671279fa 204 SUPERFAMILY SSF54211 3 131 2.39E-42 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS02055 178bd59e4db9f686a6bf537347b3f52c 462 SUPERFAMILY SSF52467 289 462 1.54E-78 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS02055 178bd59e4db9f686a6bf537347b3f52c 462 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 460 1.9E-200 T 10-03-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 RG49_RS02055 178bd59e4db9f686a6bf537347b3f52c 462 Gene3D G3DSA:3.40.50.1220 288 462 1.6E-92 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS02055 178bd59e4db9f686a6bf537347b3f52c 462 PIRSF PIRSF000204 1 462 5.6E-239 T 10-03-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 8.7E-109 T 10-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 10-03-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 Gene3D G3DSA:3.40.50.10490 23 99 9.5E-68 T 10-03-2017 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 Gene3D G3DSA:3.40.50.10490 158 236 9.5E-68 T 10-03-2017 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 PRINTS PR00395 Ribosomal protein S2 signature 196 210 8.8E-38 T 10-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 PRINTS PR00395 Ribosomal protein S2 signature 37 46 8.8E-38 T 10-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 PRINTS PR00395 Ribosomal protein S2 signature 175 186 8.8E-38 T 10-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 PRINTS PR00395 Ribosomal protein S2 signature 87 104 8.8E-38 T 10-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 PRINTS PR00395 Ribosomal protein S2 signature 158 175 8.8E-38 T 10-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 PRINTS PR00395 Ribosomal protein S2 signature 6 24 8.8E-38 T 10-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 SUPERFAMILY SSF52313 6 235 1.96E-96 T 10-03-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 10-03-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 Gene3D G3DSA:1.10.287.610 100 152 3.1E-27 T 10-03-2017 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.418 T 10-03-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 RG49_RS10975 f0974d30d7835f4b52b27c2f40e89ca4 241 Pfam PF00318 Ribosomal protein S2 9 224 3.7E-94 T 10-03-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 Pfam PF00128 Alpha amylase, catalytic domain 185 269 2.0E-7 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 SUPERFAMILY SSF51445 130 463 6.92E-127 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 SUPERFAMILY SSF51445 492 564 6.92E-127 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 Gene3D G3DSA:3.20.20.80 149 566 3.5E-108 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 Gene3D G3DSA:2.60.40.10 7 148 1.1E-54 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 11 97 1.5E-20 T 10-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 SMART SM00642 130 558 3.2E-8 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 Hamap MF_01248 Glycogen debranching enzyme [glgX]. 1 657 76.096 T 10-03-2017 IPR022844 Glycogen debranching enzyme, bacterial GO:0004553|GO:0005977 RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 SUPERFAMILY SSF81296 7 144 8.2E-47 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS17415 e39a9276ea90c77d8e83c1dc9edce5e3 657 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 7 629 1.6E-268 T 10-03-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 RG49_RS25360 a4a016f7af3c77b2fbb0869da4729061 484 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 12 167 4.4E-53 T 10-03-2017 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 RG49_RS25360 a4a016f7af3c77b2fbb0869da4729061 484 Hamap MF_01932 AMP nucleosidase [amn]. 3 484 59.993 T 10-03-2017 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 RG49_RS25360 a4a016f7af3c77b2fbb0869da4729061 484 Pfam PF01048 Phosphorylase superfamily 267 431 1.4E-18 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS25360 a4a016f7af3c77b2fbb0869da4729061 484 Gene3D G3DSA:3.30.1730.10 2 171 8.0E-68 T 10-03-2017 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 RG49_RS25360 a4a016f7af3c77b2fbb0869da4729061 484 Gene3D G3DSA:3.40.50.1580 174 466 3.4E-118 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS25360 a4a016f7af3c77b2fbb0869da4729061 484 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 11 484 1.4E-252 T 10-03-2017 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 RG49_RS25360 a4a016f7af3c77b2fbb0869da4729061 484 SUPERFAMILY SSF53167 9 484 8.77E-161 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS24875 fbf2c72bb12d39b5535a3321e981738d 379 Gene3D G3DSA:3.30.1950.10 89 164 9.1E-33 T 10-03-2017 RG49_RS24875 fbf2c72bb12d39b5535a3321e981738d 379 Gene3D G3DSA:3.10.560.10 165 244 6.8E-28 T 10-03-2017 RG49_RS24875 fbf2c72bb12d39b5535a3321e981738d 379 Pfam PF10531 SLBB domain 173 220 3.7E-7 T 10-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS24875 fbf2c72bb12d39b5535a3321e981738d 379 Pfam PF02563 Polysaccharide biosynthesis/export protein 81 165 4.4E-27 T 10-03-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 RG49_RS24875 fbf2c72bb12d39b5535a3321e981738d 379 Gene3D G3DSA:1.20.5.70 347 379 6.8E-20 T 10-03-2017 RG49_RS24875 fbf2c72bb12d39b5535a3321e981738d 379 Gene3D G3DSA:3.10.560.10 245 346 2.8E-32 T 10-03-2017 RG49_RS24055 d058991d2a34265c27e64a3eea9aed7a 351 PIRSF PIRSF006268 2 348 7.1E-90 T 10-03-2017 IPR024932 Flavin transferase ApbE GO:0017013 RG49_RS24055 d058991d2a34265c27e64a3eea9aed7a 351 SUPERFAMILY SSF143631 34 346 1.91E-94 T 10-03-2017 IPR003374 ApbE-like domain RG49_RS24055 d058991d2a34265c27e64a3eea9aed7a 351 Pfam PF02424 ApbE family 42 325 3.5E-79 T 10-03-2017 IPR024932 Flavin transferase ApbE GO:0017013 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 616 744 1.1E-43 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 382 396 - T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 Gene3D G3DSA:3.90.100.10 633 754 2.2E-31 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 141 591 1.8E-196 T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 19 135 4.6E-25 T 10-03-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 Gene3D G3DSA:3.40.640.10 141 444 2.7E-108 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 Gene3D G3DSA:3.90.1150.10 448 632 3.6E-69 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 SUPERFAMILY SSF53383 141 608 1.73E-111 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 SUPERFAMILY SSF55904 611 755 7.45E-37 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS13370 9659434d2599eab6071e32cb94b512dd 756 PIRSF PIRSF009393 1 756 2.2E-274 T 10-03-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 RG49_RS06360 89aea041e0a1526f3488ca0d2f7afd6e 371 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 362 1.4E-57 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS06360 89aea041e0a1526f3488ca0d2f7afd6e 371 Gene3D G3DSA:2.40.50.100 183 214 3.0E-13 T 10-03-2017 RG49_RS06360 89aea041e0a1526f3488ca0d2f7afd6e 371 Gene3D G3DSA:2.40.50.100 61 94 3.0E-13 T 10-03-2017 RG49_RS06360 89aea041e0a1526f3488ca0d2f7afd6e 371 SUPERFAMILY SSF111369 52 299 6.02E-28 T 10-03-2017 RG49_RS06360 89aea041e0a1526f3488ca0d2f7afd6e 371 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 49 294 2.2E-17 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS02600 0a633e4b188bd2a959403c010d5ba278 308 Gene3D G3DSA:3.40.710.10 8 308 1.3E-126 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS02600 0a633e4b188bd2a959403c010d5ba278 308 Hamap MF_00313 Glutaminase [glsA]. 6 308 47.251 T 10-03-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 RG49_RS02600 0a633e4b188bd2a959403c010d5ba278 308 Pfam PF04960 Glutaminase 24 308 6.7E-114 T 10-03-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 RG49_RS02600 0a633e4b188bd2a959403c010d5ba278 308 TIGRFAM TIGR03814 Gln_ase: glutaminase A 10 308 1.9E-131 T 10-03-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 RG49_RS02600 0a633e4b188bd2a959403c010d5ba278 308 SUPERFAMILY SSF56601 7 308 1.22E-115 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS12420 f25b14b64bcc04419659733148f8588b 878 Pfam PF00577 Outer membrane usher protein 208 790 4.5E-229 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS12420 f25b14b64bcc04419659733148f8588b 878 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 325 335 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS12420 f25b14b64bcc04419659733148f8588b 878 Pfam PF13954 PapC N-terminal domain 48 193 8.6E-51 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS12420 f25b14b64bcc04419659733148f8588b 878 Pfam PF13953 PapC C-terminal domain 799 863 1.7E-25 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS12420 f25b14b64bcc04419659733148f8588b 878 SUPERFAMILY SSF141729 46 170 1.44E-37 T 10-03-2017 RG49_RS00740 eda5dee7e7f56e3874c10c3ee4dcad95 124 Gene3D G3DSA:2.60.40.1220 26 124 1.1E-32 T 10-03-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like RG49_RS00740 eda5dee7e7f56e3874c10c3ee4dcad95 124 Pfam PF04234 CopC domain 27 123 2.4E-27 T 10-03-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 RG49_RS00740 eda5dee7e7f56e3874c10c3ee4dcad95 124 SUPERFAMILY SSF81296 26 124 3.29E-27 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS01790 eb054aa220e7391b7116f1e08101ae67 135 SUPERFAMILY SSF54593 1 130 2.69E-34 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS01790 eb054aa220e7391b7116f1e08101ae67 135 Gene3D G3DSA:3.10.180.10 1 127 3.4E-48 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS01790 eb054aa220e7391b7116f1e08101ae67 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 134 1.9E-69 T 10-03-2017 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 RG49_RS01790 eb054aa220e7391b7116f1e08101ae67 135 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 10-03-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 RG49_RS01790 eb054aa220e7391b7116f1e08101ae67 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 10-03-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 RG49_RS01790 eb054aa220e7391b7116f1e08101ae67 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 4.6E-25 T 10-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 Pfam PF07719 Tetratricopeptide repeat 329 360 1.7E-5 T 10-03-2017 IPR013105 Tetratricopeptide repeat 2 RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 Pfam PF07219 HemY protein N-terminus 26 132 6.3E-36 T 10-03-2017 IPR010817 HemY, N-terminal RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 4 385 1.5E-117 T 10-03-2017 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 Gene3D G3DSA:1.25.40.10 328 382 3.2E-16 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 Gene3D G3DSA:1.25.40.10 265 296 3.2E-16 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 Gene3D G3DSA:1.25.40.10 83 203 3.2E-16 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 SUPERFAMILY SSF48452 269 382 1.43E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS15190 cba16a328b44bab5f39e004142b4a17f 398 SUPERFAMILY SSF48452 95 226 1.43E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 Gene3D G3DSA:3.10.25.10 210 306 9.8E-39 T 10-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 10-03-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 312 7.1E-127 T 10-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 307 37.884 T 10-03-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 Pfam PF02911 Formyl transferase, C-terminal domain 207 304 1.0E-32 T 10-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 SUPERFAMILY SSF53328 5 207 4.06E-68 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 Gene3D G3DSA:3.40.50.170 4 208 1.8E-75 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 Pfam PF00551 Formyl transferase 6 183 3.6E-56 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS18165 c9e248265fc52693c7b3ee0523f40841 315 SUPERFAMILY SSF50486 208 309 6.12E-38 T 10-03-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 RG49_RS21570 46cb054f679a0d65fafe09a8fcea5404 319 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 226 318 5.7E-43 T 10-03-2017 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 RG49_RS21570 46cb054f679a0d65fafe09a8fcea5404 319 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 2 319 1.1E-190 T 10-03-2017 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 RG49_RS21570 46cb054f679a0d65fafe09a8fcea5404 319 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 4 171 1.7E-67 T 10-03-2017 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 RG49_RS05660 91b1c38f8f11ee3107655b54fc4427de 164 TIGRFAM TIGR03615 RutF: pyrimidine utilization flavin reductase protein F 4 159 2.5E-87 T 10-03-2017 IPR019917 FMN reductase (NADH) RutF GO:0008752|GO:0055114 KEGG: 00740+1.5.1.42|MetaCyc: PWY-7723 RG49_RS05660 91b1c38f8f11ee3107655b54fc4427de 164 SUPERFAMILY SSF50475 1 161 1.18E-45 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS05660 91b1c38f8f11ee3107655b54fc4427de 164 Pfam PF01613 Flavin reductase like domain 13 159 1.2E-30 T 10-03-2017 IPR002563 Flavin reductase like domain GO:0010181 RG49_RS05660 91b1c38f8f11ee3107655b54fc4427de 164 Hamap MF_00833 FMN reductase (NADH) RutF [rutF]. 1 164 43.621 T 10-03-2017 IPR019917 FMN reductase (NADH) RutF GO:0008752|GO:0055114 KEGG: 00740+1.5.1.42|MetaCyc: PWY-7723 RG49_RS05660 91b1c38f8f11ee3107655b54fc4427de 164 Gene3D G3DSA:2.30.110.10 3 157 2.7E-52 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS05660 91b1c38f8f11ee3107655b54fc4427de 164 SMART SM00903 13 158 2.7E-52 T 10-03-2017 IPR002563 Flavin reductase like domain GO:0010181 RG49_RS11175 66c96527a9f1203dc0b878b4045f5073 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 281 7.3E-132 T 10-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 RG49_RS11175 66c96527a9f1203dc0b878b4045f5073 283 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 6.7E-104 T 10-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 RG49_RS11175 66c96527a9f1203dc0b878b4045f5073 283 Gene3D G3DSA:3.40.50.620 3 176 3.9E-78 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11175 66c96527a9f1203dc0b878b4045f5073 283 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 40.409 T 10-03-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 RG49_RS11175 66c96527a9f1203dc0b878b4045f5073 283 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 23 68 1.1E-7 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS11175 66c96527a9f1203dc0b878b4045f5073 283 SUPERFAMILY SSF52374 3 281 5.9E-107 T 10-03-2017 RG49_RS11175 66c96527a9f1203dc0b878b4045f5073 283 Gene3D G3DSA:3.30.1300.10 181 282 8.4E-31 T 10-03-2017 RG49_RS12850 380d09830ef44c9247f9c44bd2772ca5 224 Pfam PF04225 Opacity-associated protein A LysM-like domain 139 223 2.3E-34 T 10-03-2017 IPR007340 Opacity-associated protein A RG49_RS12850 380d09830ef44c9247f9c44bd2772ca5 224 Pfam PF08525 Opacity-associated protein A N-terminal motif 35 62 1.7E-8 T 10-03-2017 IPR013731 Opacity-associated protein A, N-terminal RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 551 2.0E-237 T 10-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 PIRSF PIRSF004862 1 552 1.4E-188 T 10-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 PRINTS PR01009 Flagellar M-ring protein signature 263 281 9.3E-46 T 10-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 PRINTS PR01009 Flagellar M-ring protein signature 119 137 9.3E-46 T 10-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 PRINTS PR01009 Flagellar M-ring protein signature 151 165 9.3E-46 T 10-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 PRINTS PR01009 Flagellar M-ring protein signature 357 381 9.3E-46 T 10-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 PRINTS PR01009 Flagellar M-ring protein signature 194 212 9.3E-46 T 10-03-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 Pfam PF08345 Flagellar M-ring protein C-terminal 250 429 3.5E-53 T 10-03-2017 IPR013556 Flagellar M-ring C-terminal RG49_RS00220 908e6977b206a3233e9f8418d1996b50 552 Pfam PF01514 Secretory protein of YscJ/FliF family 30 218 1.4E-74 T 10-03-2017 IPR006182 Secretory protein YscJ/FliF RG49_RS19050 de7a1fa4cd3bfc3bb4937718ed6cfe88 381 Pfam PF02595 Glycerate kinase family 3 373 4.8E-150 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS19050 de7a1fa4cd3bfc3bb4937718ed6cfe88 381 SUPERFAMILY SSF110738 1 375 2.88E-142 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS19050 de7a1fa4cd3bfc3bb4937718ed6cfe88 381 PIRSF PIRSF006078 1 377 4.4E-141 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS19050 de7a1fa4cd3bfc3bb4937718ed6cfe88 381 Gene3D G3DSA:3.90.1510.10 42 274 1.3E-100 T 10-03-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 RG49_RS19050 de7a1fa4cd3bfc3bb4937718ed6cfe88 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 4.3E-175 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 Gene3D G3DSA:1.10.150.240 19 62 9.3E-6 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.6E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 95 108 3.6E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 3.6E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 3.6E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 181 3.0E-26 T 10-03-2017 IPR023214 HAD-like domain RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 6 181 5.9E-21 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 6 163 1.2E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 SUPERFAMILY SSF56784 4 203 5.56E-47 T 10-03-2017 IPR023214 HAD-like domain RG49_RS23620 9b2271ded93bd74c83d19126e302a2ed 216 Gene3D G3DSA:3.40.50.1000 63 213 1.2E-50 T 10-03-2017 IPR023214 HAD-like domain RG49_RS13890 efa68eea5b3ecb8cb067d193aa297e33 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 287 1.9E-15 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13890 efa68eea5b3ecb8cb067d193aa297e33 296 Gene3D G3DSA:1.10.3720.10 5 283 1.1E-63 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13890 efa68eea5b3ecb8cb067d193aa297e33 296 SUPERFAMILY SSF161098 8 296 1.87E-69 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS21145 ec01619fed400826cae674b7f50e4800 263 TIGRFAM TIGR00444 mazG: MazG family protein 10 257 1.7E-126 T 10-03-2017 IPR011551 NTP pyrophosphohydrolase MazG RG49_RS21145 ec01619fed400826cae674b7f50e4800 263 SUPERFAMILY SSF101386 135 236 3.36E-24 T 10-03-2017 RG49_RS21145 ec01619fed400826cae674b7f50e4800 263 SUPERFAMILY SSF101386 2 105 2.18E-26 T 10-03-2017 RG49_RS21145 ec01619fed400826cae674b7f50e4800 263 Gene3D G3DSA:1.10.287.1080 19 73 5.8E-7 T 10-03-2017 RG49_RS21145 ec01619fed400826cae674b7f50e4800 263 Gene3D G3DSA:1.10.287.1080 131 222 2.3E-13 T 10-03-2017 RG49_RS21145 ec01619fed400826cae674b7f50e4800 263 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 100 3.8E-28 T 10-03-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core RG49_RS21145 ec01619fed400826cae674b7f50e4800 263 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 169 227 1.2E-7 T 10-03-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core RG49_RS11045 f820d44147862f2bcd9e5cf6b9f34043 114 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 10 113 5.5E-39 T 10-03-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 RG49_RS11045 f820d44147862f2bcd9e5cf6b9f34043 114 Pfam PF01521 Iron-sulphur cluster biosynthesis 9 109 1.9E-20 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS11045 f820d44147862f2bcd9e5cf6b9f34043 114 Gene3D G3DSA:2.60.300.12 9 104 9.0E-32 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS11045 f820d44147862f2bcd9e5cf6b9f34043 114 SUPERFAMILY SSF89360 8 103 3.34E-31 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS11045 f820d44147862f2bcd9e5cf6b9f34043 114 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 114 37.123 T 10-03-2017 IPR023063 FeS cluster insertion protein ErpA GO:0016226 RG49_RS11045 f820d44147862f2bcd9e5cf6b9f34043 114 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 95 112 - T 10-03-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site RG49_RS13475 d9fcaa5b281933fa6ee8a46cee3a0cb1 194 PIRSF PIRSF020680 1 194 1.1E-65 T 10-03-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 RG49_RS13475 d9fcaa5b281933fa6ee8a46cee3a0cb1 194 SUPERFAMILY SSF159709 13 193 1.05E-57 T 10-03-2017 RG49_RS13475 d9fcaa5b281933fa6ee8a46cee3a0cb1 194 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 7 190 3.2E-60 T 10-03-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 RG49_RS13475 d9fcaa5b281933fa6ee8a46cee3a0cb1 194 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 6 192 1.0E-61 T 10-03-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SMART SM01211 1039 1294 2.7E-161 T 10-03-2017 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SUPERFAMILY SSF56042 818 1033 4.64E-58 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 2 1295 21.788 T 10-03-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SUPERFAMILY SSF52317 1035 1293 3.39E-100 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SUPERFAMILY SSF109736 155 220 7.45E-22 T 10-03-2017 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1039 1292 3.9E-105 T 10-03-2017 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 Gene3D G3DSA:3.30.1330.10 645 810 1.0E-16 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 Gene3D G3DSA:3.30.1330.10 211 421 1.3E-39 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 432 589 8.3E-26 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 831 966 9.8E-14 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SUPERFAMILY SSF55326 618 816 4.19E-67 T 10-03-2017 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SUPERFAMILY SSF56042 432 615 6.73E-52 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 Gene3D G3DSA:3.40.50.880 1040 1263 1.8E-12 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 4 1293 0.0 T 10-03-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SUPERFAMILY SSF55326 221 428 1.05E-64 T 10-03-2017 RG49_RS22280 7ecea86cef53e8949442373ed8cf5722 1295 SUPERFAMILY SSF82697 1 152 4.76E-54 T 10-03-2017 RG49_RS08710 f8f4894b2ba9ef23ee23d36a37b7e00f 434 SUPERFAMILY SSF53613 36 305 3.12E-45 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS08710 f8f4894b2ba9ef23ee23d36a37b7e00f 434 SUPERFAMILY SSF53613 338 416 3.12E-45 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS08710 f8f4894b2ba9ef23ee23d36a37b7e00f 434 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 352 365 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS08710 f8f4894b2ba9ef23ee23d36a37b7e00f 434 Gene3D G3DSA:3.30.1110.10 45 94 8.2E-8 T 10-03-2017 RG49_RS08710 f8f4894b2ba9ef23ee23d36a37b7e00f 434 Gene3D G3DSA:3.40.1190.20 95 298 2.2E-48 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS08710 f8f4894b2ba9ef23ee23d36a37b7e00f 434 Gene3D G3DSA:3.40.1190.20 337 433 2.2E-48 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS08710 f8f4894b2ba9ef23ee23d36a37b7e00f 434 Pfam PF00294 pfkB family carbohydrate kinase 79 293 5.5E-9 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS20875 906e95a9b8e65d3c6633793cd3ad14c5 229 Pfam PF02976 DNA mismatch repair enzyme MutH 59 157 1.5E-34 T 10-03-2017 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 RG49_RS20875 906e95a9b8e65d3c6633793cd3ad14c5 229 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 229 156.342 T 10-03-2017 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 RG49_RS20875 906e95a9b8e65d3c6633793cd3ad14c5 229 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 10 226 1.2E-116 T 10-03-2017 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 RG49_RS20875 906e95a9b8e65d3c6633793cd3ad14c5 229 Gene3D G3DSA:3.40.600.10 7 227 4.5E-81 T 10-03-2017 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 RG49_RS20875 906e95a9b8e65d3c6633793cd3ad14c5 229 SMART SM00927 59 157 1.4E-64 T 10-03-2017 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 RG49_RS20875 906e95a9b8e65d3c6633793cd3ad14c5 229 SUPERFAMILY SSF52980 7 228 5.04E-80 T 10-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 RG49_RS24980 20de7280c457906ab45ca081db1fcb35 464 TIGRFAM TIGR04004 WcaM: colanic acid biosynthesis protein WcaM 3 462 6.8E-293 T 10-03-2017 IPR023882 Colanic acid biosynthesis WcaM RG49_RS24980 20de7280c457906ab45ca081db1fcb35 464 SUPERFAMILY SSF51126 44 350 2.49E-20 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS24980 20de7280c457906ab45ca081db1fcb35 464 Gene3D G3DSA:2.160.20.10 54 350 7.8E-5 T 10-03-2017 IPR012334 Pectin lyase fold RG49_RS01640 d283e01cae141937848a5b40bd94f2a7 138 Hamap MF_01832 Cysteine desulfuration protein SufE [sufE]. 1 138 42.566 T 10-03-2017 IPR023939 Cysteine desulfuration protein SufE GO:0006790|GO:0016226 RG49_RS01640 d283e01cae141937848a5b40bd94f2a7 138 Pfam PF02657 Fe-S metabolism associated domain 12 132 1.4E-43 T 10-03-2017 IPR003808 Fe-S metabolism associated domain, SufE-like RG49_RS01640 d283e01cae141937848a5b40bd94f2a7 138 Gene3D G3DSA:3.90.1010.10 1 137 1.0E-52 T 10-03-2017 RG49_RS01640 d283e01cae141937848a5b40bd94f2a7 138 SUPERFAMILY SSF82649 2 135 1.36E-44 T 10-03-2017 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 1.4E-77 T 10-03-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1367 0.0 T 10-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 SMART SM00663 235 514 1.1E-184 T 10-03-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Gene3D G3DSA:2.40.50.100 1156 1211 5.1E-6 T 10-03-2017 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 1.9E-18 T 10-03-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 7.1E-90 T 10-03-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 4.3E-27 T 10-03-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Gene3D G3DSA:2.40.40.20 417 489 2.8E-37 T 10-03-2017 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Gene3D G3DSA:2.40.40.20 349 376 2.8E-37 T 10-03-2017 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Pfam PF00623 RNA polymerase Rpb1, domain 2 392 485 3.8E-27 T 10-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 393 1.2E-7 T 10-03-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 13 742 32.24 T 10-03-2017 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 15 1377 10.439 T 10-03-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 SUPERFAMILY SSF64484 1133 1363 0.0 T 10-03-2017 RG49_RS14150 778d1f4857f598e06e4a40b03c0153f2 1407 SUPERFAMILY SSF64484 16 944 0.0 T 10-03-2017 RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 SUPERFAMILY SSF56784 6 232 1.57E-47 T 10-03-2017 IPR023214 HAD-like domain RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 232 1.3E-13 T 10-03-2017 IPR023214 HAD-like domain RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 Hamap MF_00617 Mannosyl-3-phosphoglycerate phosphatase [mngB]. 6 253 41.681 T 10-03-2017 IPR012815 Mannosyl-3-phosphoglycerate phosphatase GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 9 268 1.7E-102 T 10-03-2017 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 231 1.3E-47 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 Gene3D G3DSA:3.30.980.20 94 179 1.9E-38 T 10-03-2017 RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 Gene3D G3DSA:3.40.50.1000 9 89 2.9E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 Gene3D G3DSA:3.40.50.1000 180 264 2.9E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS00135 874b326630e0c9f6d030be7c367224ba 271 TIGRFAM TIGR02463 MPGP_rel: mannosyl-3-phosphoglycerate phosphatase homolog 9 232 4.4E-101 T 10-03-2017 RG49_RS01210 193a16e82d36d00006825dbeb6d1dba4 217 Gene3D G3DSA:3.40.50.300 1 198 2.4E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01210 193a16e82d36d00006825dbeb6d1dba4 217 SMART SM00382 26 214 1.8E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS01210 193a16e82d36d00006825dbeb6d1dba4 217 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS01210 193a16e82d36d00006825dbeb6d1dba4 217 SUPERFAMILY SSF52540 1 198 8.92E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01210 193a16e82d36d00006825dbeb6d1dba4 217 Pfam PF00005 ABC transporter 17 161 1.4E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 SUPERFAMILY SSF55781 26 168 4.36E-11 T 10-03-2017 IPR029016 GAF domain-like RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 SUPERFAMILY SSF52540 380 618 1.56E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Pfam PF01590 GAF domain 202 344 9.4E-12 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Gene3D G3DSA:3.30.450.40 182 353 7.9E-24 T 10-03-2017 IPR029016 GAF domain-like RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Gene3D G3DSA:3.30.450.40 12 166 6.8E-9 T 10-03-2017 IPR029016 GAF domain-like RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 667 687 7.0E-5 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 603 620 7.0E-5 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Gene3D G3DSA:1.10.10.60 607 687 2.2E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 SMART SM00065 202 354 1.6E-25 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 SMART SM00065 26 174 2.6E-13 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 SMART SM00382 401 545 8.3E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 SUPERFAMILY SSF55781 184 360 2.4E-21 T 10-03-2017 IPR029016 GAF domain-like RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 SUPERFAMILY SSF46689 593 687 1.25E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Gene3D G3DSA:3.40.50.300 377 553 1.4E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Pfam PF02954 Bacterial regulatory protein, Fis family 645 684 3.0E-5 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 594 603 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Gene3D G3DSA:1.10.8.60 554 606 2.7E-23 T 10-03-2017 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 405 418 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS21420 5ba0b553796eb4c26033d4022971e24f 692 Pfam PF00158 Sigma-54 interaction domain 381 548 2.6E-70 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 Gene3D G3DSA:1.10.8.60 275 336 2.8E-33 T 10-03-2017 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 Gene3D G3DSA:3.20.20.70 4 262 7.1E-58 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 272 335 2.0E-29 T 10-03-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 Pfam PF00682 HMGL-like 6 262 5.4E-77 T 10-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 4 336 1.7E-181 T 10-03-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 Pfam PF07836 DmpG-like communication domain 274 334 2.3E-30 T 10-03-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 SUPERFAMILY SSF51569 3 276 1.48E-68 T 10-03-2017 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 337 226.18 T 10-03-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS09930 8d771ee0e88e188b97baf3748886662b 337 SUPERFAMILY SSF89000 288 336 3.92E-18 T 10-03-2017 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 569 3.2E-283 T 10-03-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Pfam PF03129 Anticodon binding domain 475 568 3.2E-21 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Gene3D G3DSA:3.40.50.800 470 570 7.6E-32 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Gene3D G3DSA:3.30.930.10 407 468 3.7E-108 T 10-03-2017 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Gene3D G3DSA:3.30.930.10 1 228 3.7E-108 T 10-03-2017 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.2E-19 T 10-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.2E-19 T 10-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.2E-19 T 10-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.2E-19 T 10-03-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 459 6.6E-49 T 10-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 SUPERFAMILY SSF55681 407 478 1.82E-109 T 10-03-2017 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 SUPERFAMILY SSF55681 10 237 1.82E-109 T 10-03-2017 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 PIRSF PIRSF001535 1 572 9.9E-279 T 10-03-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Gene3D G3DSA:3.90.960.10 250 388 6.4E-32 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 571 43.231 T 10-03-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 Pfam PF04073 Aminoacyl-tRNA editing domain 257 376 1.4E-26 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 SUPERFAMILY SSF55826 218 390 1.01E-30 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS10840 5e38a1a0098b9f67a88214ef7065284e 572 SUPERFAMILY SSF52954 463 571 1.21E-33 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 866 958 1.11E-5 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 1081 1206 3.53E-17 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 157 281 7.19E-22 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 7.2E-9 T 10-03-2017 IPR024973 ESPR domain RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF03895 YadA-like C-terminal region 1540 1616 3.8E-24 T 10-03-2017 IPR005594 YadA-like, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 200 226 1.3E-4 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1411 1435 1.9E-4 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 285 308 4.2E-5 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 298 323 1.1E-5 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 327 351 1.0E-4 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 158 182 1.2E-5 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 353 379 1.0E-4 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1099 1125 3.1E-7 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 257 281 3.8E-6 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 269 295 1.9E-6 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1397 1423 3.7E-7 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05658 Head domain of trimeric autotransporter adhesin 228 253 7.0E-6 T 10-03-2017 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF54523 1453 1460 1.88E-25 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF54523 1525 1616 1.88E-25 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:3.30.1300.30 1525 1616 2.3E-34 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 1226 1340 7.72E-24 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 761 858 1.83E-6 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 258 409 6.41E-34 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 570 592 3.6E-7 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1319 1339 2.9E-10 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 479 500 1.1E-6 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 655 677 9.9E-9 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1028 1049 6.2E-9 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1183 1203 1.6E-6 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1440 1460 1.3E-9 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 382 405 8.6E-7 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 933 954 2.7E-6 T 10-03-2017 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 69 198 2.35E-16 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 1384 1462 1.83E-17 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:1.20.5.170 478 563 2.5E-14 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:1.20.5.170 1329 1381 2.2E-11 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:1.20.5.170 651 708 2.1E-9 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:1.20.5.170 1040 1089 3.5E-9 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:1.20.5.170 730 826 4.0E-6 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:1.20.5.170 565 641 1.5E-10 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 1090 1205 4.5E-18 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 1226 1328 2.4E-20 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 68 223 1.2E-29 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 1487 1517 2.5E-4 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 1392 1462 1.4E-23 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 867 957 8.3E-5 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 224 409 2.2E-47 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 Gene3D G3DSA:2.150.10.10 965 1039 1.6E-5 T 10-03-2017 IPR011049 Serralysin-like metalloprotease, C-terminal RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 1479 1515 7.72E-6 T 10-03-2017 RG49_RS16395 830f7da5cb662b1b13b3a494f4b2b71d 1616 SUPERFAMILY SSF101967 963 1053 1.7E-6 T 10-03-2017 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 SUPERFAMILY SSF51735 317 652 9.43E-76 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Hamap MF_01166 Bifunctional polymyxin resistance protein ArnA [arnA]. 1 660 67.076 T 10-03-2017 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Gene3D G3DSA:3.90.25.10 570 641 7.0E-46 T 10-03-2017 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 PIRSF PIRSF036506 1 660 0.0 T 10-03-2017 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 SUPERFAMILY SSF53328 1 202 1.44E-54 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Pfam PF00551 Formyl transferase 53 175 7.1E-24 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 SUPERFAMILY SSF50486 204 304 1.11E-24 T 10-03-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Pfam PF01370 NAD dependent epimerase/dehydratase family 318 566 2.1E-46 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Pfam PF02911 Formyl transferase, C-terminal domain 202 294 4.5E-19 T 10-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Gene3D G3DSA:3.10.25.10 204 305 5.3E-24 T 10-03-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Gene3D G3DSA:3.40.50.170 1 199 2.8E-49 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS23820 01fa82bf61c0f15e0e2df18b7115ea2a 660 Gene3D G3DSA:3.40.50.720 306 553 1.4E-44 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01740 0eed03ff499fcc5d2f9d6c4e4d9fc8bc 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 6.3E-20 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS01740 0eed03ff499fcc5d2f9d6c4e4d9fc8bc 310 Gene3D G3DSA:1.10.10.10 6 88 2.8E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS01740 0eed03ff499fcc5d2f9d6c4e4d9fc8bc 310 SUPERFAMILY SSF46785 6 88 2.18E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS01740 0eed03ff499fcc5d2f9d6c4e4d9fc8bc 310 SUPERFAMILY SSF53850 88 290 2.9E-27 T 10-03-2017 RG49_RS01740 0eed03ff499fcc5d2f9d6c4e4d9fc8bc 310 Gene3D G3DSA:3.40.190.10 89 173 1.1E-7 T 10-03-2017 RG49_RS01740 0eed03ff499fcc5d2f9d6c4e4d9fc8bc 310 Pfam PF03466 LysR substrate binding domain 88 290 2.8E-25 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS01740 0eed03ff499fcc5d2f9d6c4e4d9fc8bc 310 Gene3D G3DSA:3.40.190.10 174 257 1.6E-4 T 10-03-2017 RG49_RS13155 7fd9360c2b37e65328cd3f220502fd9b 131 PIRSF PIRSF000180 2 130 4.8E-63 T 10-03-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 RG49_RS13155 7fd9360c2b37e65328cd3f220502fd9b 131 ProDom PD015900 FUMARATE MEMBRANE REDUCTASE C SUBUNIT TRANSMEMBRANE INNER HYDROPHOBIC REDUCTASE POLYPEPTIDE 8 129 4.0E-56 T 10-03-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 RG49_RS13155 7fd9360c2b37e65328cd3f220502fd9b 131 Pfam PF02300 Fumarate reductase subunit C 3 128 1.0E-56 T 10-03-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 RG49_RS13155 7fd9360c2b37e65328cd3f220502fd9b 131 SUPERFAMILY SSF81343 2 131 5.36E-59 T 10-03-2017 RG49_RS13155 7fd9360c2b37e65328cd3f220502fd9b 131 Hamap MF_00708 Fumarate reductase subunit C [frdC]. 2 128 30.453 T 10-03-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 RG49_RS13155 7fd9360c2b37e65328cd3f220502fd9b 131 Gene3D G3DSA:1.20.1300.10 3 130 1.5E-59 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Gene3D G3DSA:1.10.287.610 1 67 1.7E-30 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Pfam PF14520 Helix-hairpin-helix domain 446 502 1.4E-5 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SUPERFAMILY SSF47781 403 583 8.15E-62 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 318 4.2E-143 T 10-03-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SMART SM00278 446 465 24.0 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SMART SM00278 480 499 0.59 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SMART SM00278 512 531 600.0 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SMART SM00278 544 563 38.0 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 596 669 7.4E-14 T 10-03-2017 IPR001357 BRCT domain RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 665 3.2E-279 T 10-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SUPERFAMILY SSF56091 2 316 2.59E-124 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Gene3D G3DSA:3.40.50.10190 594 669 2.0E-26 T 10-03-2017 IPR001357 BRCT domain RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Gene3D G3DSA:1.10.150.20 504 584 6.0E-32 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Gene3D G3DSA:2.40.50.140 319 391 1.1E-34 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SMART SM00532 3 448 8.8E-297 T 10-03-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 10-03-2017 IPR018239 NAD-dependent DNA ligase, active site RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SUPERFAMILY SSF52113 596 669 3.6E-19 T 10-03-2017 IPR001357 BRCT domain RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Hamap MF_01588 DNA ligase [ligA]. 2 669 55.086 T 10-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Gene3D G3DSA:3.30.470.30 119 252 1.1E-50 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 PIRSF PIRSF001604 1 671 3.6E-257 T 10-03-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Pfam PF12826 Helix-hairpin-helix motif 510 573 4.2E-23 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 322 398 8.3E-36 T 10-03-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 331 346 - T 10-03-2017 IPR033136 NAD-dependent DNA ligase, conserved site RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Gene3D G3DSA:1.10.150.20 435 502 2.4E-28 T 10-03-2017 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 407 434 3.9E-11 T 10-03-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SMART SM00292 595 670 5.6E-14 T 10-03-2017 IPR001357 BRCT domain RG49_RS23075 e670abef1f47c5d874183e1212cce4af 671 SUPERFAMILY SSF50249 318 400 8.74E-29 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS15265 2d44253ccbbe269979305f02196891aa 293 Pfam PF00483 Nucleotidyl transferase 2 238 8.9E-71 T 10-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 RG49_RS15265 2d44253ccbbe269979305f02196891aa 293 SUPERFAMILY SSF53448 1 286 1.89E-91 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS15265 2d44253ccbbe269979305f02196891aa 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 8.1E-161 T 10-03-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 RG49_RS15265 2d44253ccbbe269979305f02196891aa 293 Gene3D G3DSA:3.90.550.10 1 264 7.9E-65 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 3 191 1.1E-82 T 10-03-2017 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-6317|MetaCyc: PWY-7459 RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 4 190 2.2E-69 T 10-03-2017 IPR010976 Beta-phosphoglucomutase hydrolase RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 Gene3D G3DSA:1.10.150.240 17 92 1.6E-28 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 62 190 5.4E-20 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 Gene3D G3DSA:3.40.50.1000 1 16 3.9E-31 T 10-03-2017 IPR023214 HAD-like domain RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 Gene3D G3DSA:3.40.50.1000 96 213 3.9E-31 T 10-03-2017 IPR023214 HAD-like domain RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 SUPERFAMILY SSF56784 3 198 1.5E-41 T 10-03-2017 IPR023214 HAD-like domain RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 3.7E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.7E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 3.7E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS03955 bf9e983c20f62225bfb3640f02791fad 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 189 1.2E-23 T 10-03-2017 IPR023214 HAD-like domain RG49_RS25365 3c489f85cc16db5417a5d7aaa1015e40 438 Pfam PF07690 Major Facilitator Superfamily 273 431 1.3E-10 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS25365 3c489f85cc16db5417a5d7aaa1015e40 438 SUPERFAMILY SSF103473 21 434 2.22E-57 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS25365 3c489f85cc16db5417a5d7aaa1015e40 438 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 30 425 5.0E-151 T 10-03-2017 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 RG49_RS25365 3c489f85cc16db5417a5d7aaa1015e40 438 Pfam PF00083 Sugar (and other) transporter 28 236 6.6E-17 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS25365 3c489f85cc16db5417a5d7aaa1015e40 438 Gene3D G3DSA:1.20.1250.20 253 437 4.2E-21 T 10-03-2017 RG49_RS25365 3c489f85cc16db5417a5d7aaa1015e40 438 Gene3D G3DSA:1.20.1250.20 22 229 1.5E-18 T 10-03-2017 RG49_RS25365 3c489f85cc16db5417a5d7aaa1015e40 438 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 Gene3D G3DSA:2.60.40.1070 151 232 6.6E-27 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 27 149 3.6E-26 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 SUPERFAMILY SSF49584 143 228 3.79E-23 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 PRINTS PR00969 Pili chaperone signature 108 125 2.9E-25 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 PRINTS PR00969 Pili chaperone signature 28 37 2.9E-25 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 PRINTS PR00969 Pili chaperone signature 79 100 2.9E-25 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 PRINTS PR00969 Pili chaperone signature 131 146 2.9E-25 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 PRINTS PR00969 Pili chaperone signature 166 181 2.9E-25 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 107 124 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 Gene3D G3DSA:2.60.40.360 27 149 1.5E-30 T 10-03-2017 IPR008962 PapD-like RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 172 228 4.8E-14 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS06000 03bbf7ed385172c5b08ce47bd248169b 236 SUPERFAMILY SSF49354 25 149 3.92E-27 T 10-03-2017 IPR008962 PapD-like RG49_RS13165 8134fb03b8fbc771ef960096536202ea 377 SUPERFAMILY SSF56601 22 376 4.0E-106 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS13165 8134fb03b8fbc771ef960096536202ea 377 Pfam PF00144 Beta-lactamase 30 376 1.7E-87 T 10-03-2017 IPR001466 Beta-lactamase-related RG49_RS13165 8134fb03b8fbc771ef960096536202ea 377 ProSitePatterns PS00336 Beta-lactamase class-C active site. 76 83 - T 10-03-2017 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 RG49_RS13165 8134fb03b8fbc771ef960096536202ea 377 Gene3D G3DSA:3.40.710.10 22 376 1.7E-96 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 SUPERFAMILY SSF54631 177 314 5.98E-23 T 10-03-2017 RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 SUPERFAMILY SSF56176 325 407 1.2E-21 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 Pfam PF01595 Domain of unknown function DUF21 2 169 9.5E-49 T 10-03-2017 IPR002550 Domain of unknown function DUF21 RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 SMART SM01091 327 405 1.7E-25 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 Gene3D G3DSA:3.10.580.10 176 315 1.1E-12 T 10-03-2017 RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 Pfam PF00571 CBS domain 263 311 1.2E-4 T 10-03-2017 IPR000644 CBS domain RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 Gene3D G3DSA:3.30.465.10 325 403 8.3E-25 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS21970 02e1bca41ed82d7c403c4d61f8e3d64e 413 Pfam PF03471 Transporter associated domain 329 403 8.5E-19 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS17975 18aab782a720095b386e0154424bdc47 654 Pfam PF03958 Bacterial type II/III secretion system short domain 197 266 5.4E-17 T 10-03-2017 IPR005644 NolW-like RG49_RS17975 18aab782a720095b386e0154424bdc47 654 Pfam PF03958 Bacterial type II/III secretion system short domain 272 351 1.1E-15 T 10-03-2017 IPR005644 NolW-like RG49_RS17975 18aab782a720095b386e0154424bdc47 654 Pfam PF03958 Bacterial type II/III secretion system short domain 131 190 8.1E-11 T 10-03-2017 IPR005644 NolW-like RG49_RS17975 18aab782a720095b386e0154424bdc47 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 351 361 1.1E-42 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17975 18aab782a720095b386e0154424bdc47 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 563 581 1.1E-42 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17975 18aab782a720095b386e0154424bdc47 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 586 600 1.1E-42 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17975 18aab782a720095b386e0154424bdc47 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 433 457 1.1E-42 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17975 18aab782a720095b386e0154424bdc47 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 468 478 1.1E-42 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS17975 18aab782a720095b386e0154424bdc47 654 Pfam PF00263 Bacterial type II and III secretion system protein 437 599 2.1E-51 T 10-03-2017 IPR004846 Type II/III secretion system GO:0009306 RG49_RS17975 18aab782a720095b386e0154424bdc47 654 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 34 608 2.9E-195 T 10-03-2017 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 RG49_RS17975 18aab782a720095b386e0154424bdc47 654 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 544 577 - T 10-03-2017 IPR004845 Type II secretion system GspD, conserved site GO:0008565 RG49_RS11620 0fc0ae6392796ac6c2286821ebe1190b 280 Pfam PF00149 Calcineurin-like phosphoesterase 4 147 3.7E-14 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS11620 0fc0ae6392796ac6c2286821ebe1190b 280 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 271 52.778 T 10-03-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 RG49_RS11620 0fc0ae6392796ac6c2286821ebe1190b 280 PIRSF PIRSF000903 1 274 1.5E-125 T 10-03-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 RG49_RS11620 0fc0ae6392796ac6c2286821ebe1190b 280 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 278 1.9E-168 T 10-03-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 RG49_RS11620 0fc0ae6392796ac6c2286821ebe1190b 280 SUPERFAMILY SSF56300 1 259 5.11E-57 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS11620 0fc0ae6392796ac6c2286821ebe1190b 280 Gene3D G3DSA:3.60.21.10 1 132 3.5E-55 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS11620 0fc0ae6392796ac6c2286821ebe1190b 280 Gene3D G3DSA:3.60.21.10 169 267 3.5E-55 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 Pfam PF13291 ACT domain 622 699 4.3E-17 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 Pfam PF02824 TGS domain 388 447 1.7E-21 T 10-03-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 SUPERFAMILY SSF55021 627 699 1.51E-5 T 10-03-2017 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 Pfam PF13328 HD domain 26 175 2.9E-53 T 10-03-2017 IPR003607 HD/PDEase domain RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 Gene3D G3DSA:3.30.460.10 178 324 5.7E-48 T 10-03-2017 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 SUPERFAMILY SSF109604 3 190 2.7E-75 T 10-03-2017 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 SMART SM00954 235 345 2.8E-63 T 10-03-2017 IPR007685 RelA/SpoT GO:0015969 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 9.4E-36 T 10-03-2017 IPR007685 RelA/SpoT GO:0015969 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 SMART SM00471 41 153 1.2E-11 T 10-03-2017 IPR003607 HD/PDEase domain RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 Gene3D G3DSA:3.30.70.260 627 697 1.3E-6 T 10-03-2017 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 699 1.3E-294 T 10-03-2017 IPR004811 RelA/SpoT family GO:0015969 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 SUPERFAMILY SSF81301 180 392 1.52E-62 T 10-03-2017 RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 Gene3D G3DSA:3.10.20.30 387 448 4.1E-23 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS16145 e9c7308db07449ea2716124d80ee40c4 702 SUPERFAMILY SSF81271 375 447 3.71E-21 T 10-03-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 RG49_RS13950 86e49383df817859f3cd644300bf75d7 90 ProDom PD063639 YJBD CYTOPLASMIC STY4411 YPO2363 ECS5006 Y1969 3 90 2.0E-33 T 10-03-2017 IPR020317 Uncharacterised protein family YjbD RG49_RS13950 86e49383df817859f3cd644300bf75d7 90 Pfam PF11656 YjbD family (DUF3811) 3 90 2.5E-38 T 10-03-2017 IPR020317 Uncharacterised protein family YjbD RG49_RS24460 7fc6198ad0e72c7774675f8752b6dd6b 231 Pfam PF04172 LrgB-like family 12 224 1.2E-79 T 10-03-2017 IPR007300 CidB/LrgB family RG49_RS24460 7fc6198ad0e72c7774675f8752b6dd6b 231 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 2 226 1.5E-110 T 10-03-2017 IPR005261 Conserved hypothetical protein CHP00659 RG49_RS05380 6c599b7fb76e732c980913832a93871c 306 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 4 306 51.914 T 10-03-2017 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 RG49_RS05380 6c599b7fb76e732c980913832a93871c 306 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 5 306 1.3E-150 T 10-03-2017 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 RG49_RS05380 6c599b7fb76e732c980913832a93871c 306 PIRSF PIRSF026649 2 306 9.8E-114 T 10-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 RG49_RS05380 6c599b7fb76e732c980913832a93871c 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 297 2.4E-122 T 10-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 15 505 2.4E-241 T 10-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 Gene3D G3DSA:3.30.930.10 157 500 1.2E-123 T 10-03-2017 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 SUPERFAMILY SSF55681 162 502 2.87E-123 T 10-03-2017 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 Gene3D G3DSA:2.40.50.140 16 154 1.8E-49 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 SUPERFAMILY SSF50249 13 155 9.3E-48 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 505 45.612 T 10-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 501 6.4E-84 T 10-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 1.5E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 1.5E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 1.5E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 1.5E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 1.5E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 PIRSF PIRSF039101 1 505 5.6E-210 T 10-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13290 b245d5fa5d26276e008a2c8c37d3471e 505 Pfam PF01336 OB-fold nucleic acid binding domain 68 146 1.4E-15 T 10-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Gene3D G3DSA:2.40.50.140 634 720 3.9E-29 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Pfam PF12836 Helix-hairpin-helix motif 491 555 1.4E-28 T 10-03-2017 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 SMART SM00316 649 720 1.0E-26 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 SUPERFAMILY SSF158832 2 322 1.27E-121 T 10-03-2017 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 SMART SM00732 327 424 1.0E-34 T 10-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Gene3D G3DSA:1.10.3500.10 111 323 6.2E-105 T 10-03-2017 IPR023323 Tex-like domain RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Gene3D G3DSA:1.10.3500.10 451 498 6.2E-105 T 10-03-2017 IPR023323 Tex-like domain RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 SUPERFAMILY SSF47781 560 632 5.56E-20 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 SUPERFAMILY SSF50249 638 723 3.36E-25 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Gene3D G3DSA:3.30.420.140 328 450 7.5E-50 T 10-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Pfam PF09371 Tex-like protein N-terminal domain 10 194 4.3E-70 T 10-03-2017 IPR018974 Tex-like protein, N-terminal RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 SUPERFAMILY SSF47781 470 558 5.0E-28 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Pfam PF16921 Tex protein YqgF-like domain 328 451 1.7E-50 T 10-03-2017 IPR032639 Tex protein, YqgF-like domain RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 SUPERFAMILY SSF53098 323 469 9.36E-49 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Gene3D G3DSA:1.10.10.650 2 110 1.5E-46 T 10-03-2017 IPR023319 Tex-like protein, HTH domain RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Pfam PF00575 S1 RNA binding domain 649 720 4.2E-24 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS17540 be65959ea1375f9eeea55b5516a6b689 773 Gene3D G3DSA:1.10.150.310 499 630 1.6E-48 T 10-03-2017 IPR023097 Tex RuvX-like domain RG49_RS18955 744096e9045c70e0d5fdee473cde6033 263 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 4 263 1.1E-125 T 10-03-2017 IPR018405 Phosphotransferase system, mannose/fructose/sorbose family IID component, subgroup GO:0009401|GO:0016021 RG49_RS18955 744096e9045c70e0d5fdee473cde6033 263 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 5 263 3.0E-90 T 10-03-2017 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 Gene3D G3DSA:3.40.50.1770 202 371 4.2E-47 T 10-03-2017 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 10-03-2017 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 SMART SM01002 146 311 5.5E-85 T 10-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 9.4E-52 T 10-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 510 0.0 T 10-03-2017 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 427 509 3.9E-36 T 10-03-2017 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 SUPERFAMILY SSF52283 1 168 1.02E-56 T 10-03-2017 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 SUPERFAMILY SSF51735 137 317 1.69E-38 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 368 1.7E-76 T 10-03-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 Gene3D G3DSA:3.40.50.1770 1 168 1.1E-69 T 10-03-2017 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 170 195 - T 10-03-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 Gene3D G3DSA:3.50.50.60 169 201 4.7E-6 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 SMART SM01003 4 137 5.3E-76 T 10-03-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal RG49_RS02050 f69ce3912019278710d3fa6e9e1d35a6 510 PIRSF PIRSF000203 1 509 1.2E-288 T 10-03-2017 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 RG49_RS22010 ed2621c2eb131c64c689d6fc4d0f00e5 408 SMART SM00267 238 408 1.2E-58 T 10-03-2017 IPR000160 GGDEF domain RG49_RS22010 ed2621c2eb131c64c689d6fc4d0f00e5 408 Pfam PF17152 Periplasmic sensor domain 45 145 4.6E-30 T 10-03-2017 IPR033417 Periplasmic sensor domain CHASE8 RG49_RS22010 ed2621c2eb131c64c689d6fc4d0f00e5 408 Pfam PF00990 Diguanylate cyclase, GGDEF domain 249 403 1.9E-45 T 10-03-2017 IPR000160 GGDEF domain RG49_RS22010 ed2621c2eb131c64c689d6fc4d0f00e5 408 Gene3D G3DSA:3.30.70.270 251 405 3.0E-42 T 10-03-2017 RG49_RS22010 ed2621c2eb131c64c689d6fc4d0f00e5 408 SUPERFAMILY SSF55073 254 402 7.69E-36 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS22010 ed2621c2eb131c64c689d6fc4d0f00e5 408 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 247 405 4.8E-35 T 10-03-2017 IPR000160 GGDEF domain RG49_RS06020 4e576e5dead09753b4c927bba256175c 866 SUPERFAMILY SSF141729 61 174 6.15E-36 T 10-03-2017 RG49_RS06020 4e576e5dead09753b4c927bba256175c 866 Pfam PF13953 PapC C-terminal domain 789 851 5.2E-17 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS06020 4e576e5dead09753b4c927bba256175c 866 Pfam PF13954 PapC N-terminal domain 39 183 5.5E-50 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS06020 4e576e5dead09753b4c927bba256175c 866 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 312 322 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS06020 4e576e5dead09753b4c927bba256175c 866 Pfam PF00577 Outer membrane usher protein 201 777 2.1E-221 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24970 1828199c5d1333255be25bbc1284a356 426 TIGRFAM TIGR04006 wcaK: colanic acid biosynthesis pyruvyl transferase WcaK 1 426 1.0E-282 T 10-03-2017 IPR023918 Colanic acid biosynthesis, pyruvyl transferase, WcaK RG49_RS24970 1828199c5d1333255be25bbc1284a356 426 Pfam PF04230 Polysaccharide pyruvyl transferase 13 356 7.7E-40 T 10-03-2017 IPR007345 Polysaccharide pyruvyl transferase RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Pfam PF06827 Zinc finger found in FPG and IleRS 898 926 4.0E-9 T 10-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Gene3D G3DSA:1.10.730.10 641 827 4.1E-43 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 SUPERFAMILY SSF50677 204 403 3.66E-56 T 10-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 401 416 5.6E-33 T 10-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 526 539 5.6E-33 T 10-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 238 261 5.6E-33 T 10-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 5.6E-33 T 10-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 561 570 5.6E-33 T 10-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 843 0.0 T 10-03-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Pfam PF08264 Anticodon-binding domain of tRNA 685 840 5.3E-27 T 10-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Gene3D G3DSA:3.90.740.10 206 389 4.7E-58 T 10-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 641 1.1E-241 T 10-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 SUPERFAMILY SSF47323 652 929 8.97E-80 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Gene3D G3DSA:3.40.50.620 403 636 6.3E-135 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Gene3D G3DSA:3.40.50.620 17 205 6.3E-135 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 SUPERFAMILY SSF52374 403 648 4.9E-137 T 10-03-2017 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 SUPERFAMILY SSF52374 3 202 4.9E-137 T 10-03-2017 RG49_RS11740 334e33669ff35afdbc34921d64e12e44 938 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 929 21.594 T 10-03-2017 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 SUPERFAMILY SSF48208 9 350 4.42E-103 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 Gene3D G3DSA:1.50.10.10 6 355 2.9E-99 T 10-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 ProSitePatterns PS00812 Glycosyl hydrolases family 8 signature. 114 132 - T 10-03-2017 IPR019834 Glycoside hydrolase, family 8, conserved site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 Pfam PF01270 Glycosyl hydrolases family 8 1 346 2.1E-149 T 10-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 114 132 3.1E-21 T 10-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 52 65 3.1E-21 T 10-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 331 345 3.1E-21 T 10-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 215 226 3.1E-21 T 10-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 240 249 3.1E-21 T 10-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS16860 7eb98f05ae6512139ad72350ab25dbdf 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 179 196 3.1E-21 T 10-03-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 RG49_RS18130 4363326f335edc2987d8e609b33aa633 127 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.022 T 10-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18130 4363326f335edc2987d8e609b33aa633 127 SUPERFAMILY SSF64263 1 118 3.4E-51 T 10-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18130 4363326f335edc2987d8e609b33aa633 127 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 10-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18130 4363326f335edc2987d8e609b33aa633 127 Pfam PF01196 Ribosomal protein L17 20 116 1.2E-34 T 10-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18130 4363326f335edc2987d8e609b33aa633 127 Gene3D G3DSA:3.90.1030.10 1 117 2.4E-51 T 10-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18130 4363326f335edc2987d8e609b33aa633 127 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 6.7E-51 T 10-03-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS04835 8f6c42cc6b1296c0f4b942a0f8f61dc2 94 Pfam PF13436 Glycine-zipper domain 5 41 0.027 T 10-03-2017 IPR025693 Glycine-zipper-containing OmpA-like membrane domain RG49_RS04835 8f6c42cc6b1296c0f4b942a0f8f61dc2 94 Pfam PF13488 Glycine zipper 54 93 2.0E-5 T 10-03-2017 RG49_RS08035 2bf4dbadb6f030f580754e5d6a4776b1 302 PIRSF PIRSF015582 1 302 1.0E-75 T 10-03-2017 IPR011206 Citrate lyase beta subunit-like RG49_RS08035 2bf4dbadb6f030f580754e5d6a4776b1 302 TIGRFAM TIGR01588 citE: citrate (pro-3S)-lyase, beta subunit 12 299 1.7E-136 T 10-03-2017 IPR006475 Citrate lyase, beta subunit, bacteria GO:0005737|GO:0006084|GO:0008816|GO:0009346 KEGG: 00720+4.1.3.34|MetaCyc: PWY-5392|MetaCyc: PWY-6038 RG49_RS08035 2bf4dbadb6f030f580754e5d6a4776b1 302 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 234 1.9E-83 T 10-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 RG49_RS08035 2bf4dbadb6f030f580754e5d6a4776b1 302 Gene3D G3DSA:3.20.20.60 9 245 1.8E-73 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS08035 2bf4dbadb6f030f580754e5d6a4776b1 302 SUPERFAMILY SSF51621 11 244 6.28E-62 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 1.1E-13 T 10-03-2017 RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 Gene3D G3DSA:1.10.10.10 1 57 4.8E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 10-03-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 5.7E-14 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 5.7E-14 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 5.7E-14 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 SUPERFAMILY SSF46785 4 66 1.06E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 Pfam PF01037 Lrp/AsnC ligand binding domain 76 143 6.5E-18 T 10-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 SUPERFAMILY SSF54909 68 152 2.28E-19 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 Gene3D G3DSA:3.30.70.920 70 143 9.9E-23 T 10-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain RG49_RS15495 8aa5523875d6f43ba583137b1e8cb515 152 SMART SM00344 6 113 7.8E-45 T 10-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 RG49_RS12355 7cbd5b2fcab772bec69158cce8668da0 153 Pfam PF07670 Nucleoside recognition 27 90 6.6E-9 T 10-03-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 RG49_RS06060 25bd22e9b5cb6c0d4d982cb7db274698 255 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06060 25bd22e9b5cb6c0d4d982cb7db274698 255 SMART SM00382 36 210 2.4E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06060 25bd22e9b5cb6c0d4d982cb7db274698 255 Gene3D G3DSA:3.40.50.300 12 212 2.2E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06060 25bd22e9b5cb6c0d4d982cb7db274698 255 SUPERFAMILY SSF52540 13 213 6.37E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06060 25bd22e9b5cb6c0d4d982cb7db274698 255 Pfam PF00005 ABC transporter 27 160 2.9E-29 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17430 de02fab504f927d206068d5387fdffc0 815 SUPERFAMILY SSF53756 9 814 0.0 T 10-03-2017 RG49_RS17430 de02fab504f927d206068d5387fdffc0 815 Gene3D G3DSA:3.40.50.2000 11 479 2.0E-208 T 10-03-2017 RG49_RS17430 de02fab504f927d206068d5387fdffc0 815 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 654 666 - T 10-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17430 de02fab504f927d206068d5387fdffc0 815 Pfam PF00343 Carbohydrate phosphorylase 102 810 0.0 T 10-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17430 de02fab504f927d206068d5387fdffc0 815 PIRSF PIRSF000460 2 815 2.7E-234 T 10-03-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17430 de02fab504f927d206068d5387fdffc0 815 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 14 810 0.0 T 10-03-2017 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 RG49_RS17430 de02fab504f927d206068d5387fdffc0 815 Gene3D G3DSA:3.40.50.2000 480 795 4.8E-142 T 10-03-2017 RG49_RS24320 3e4c32d28b0bea753a45d03181153eea 563 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 107 190 7.1E-40 T 10-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 RG49_RS24320 3e4c32d28b0bea753a45d03181153eea 563 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 108 194 1.4E-18 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS24320 3e4c32d28b0bea753a45d03181153eea 563 SUPERFAMILY SSF52794 4 88 1.62E-9 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS24320 3e4c32d28b0bea753a45d03181153eea 563 SUPERFAMILY SSF52794 105 206 3.84E-35 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS24320 3e4c32d28b0bea753a45d03181153eea 563 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 213 552 1.6E-151 T 10-03-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 RG49_RS24320 3e4c32d28b0bea753a45d03181153eea 563 Gene3D G3DSA:3.40.50.2300 102 206 2.3E-42 T 10-03-2017 RG49_RS24320 3e4c32d28b0bea753a45d03181153eea 563 Pfam PF02378 Phosphotransferase system, EIIC 233 496 3.9E-19 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS20490 bce778af12934d14b6a409ad4a4e73dc 439 Gene3D G3DSA:2.30.40.10 33 82 2.2E-7 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20490 bce778af12934d14b6a409ad4a4e73dc 439 SUPERFAMILY SSF51338 33 91 9.79E-9 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20490 bce778af12934d14b6a409ad4a4e73dc 439 Pfam PF01979 Amidohydrolase family 74 435 5.1E-83 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS20490 bce778af12934d14b6a409ad4a4e73dc 439 SUPERFAMILY SSF51556 76 379 2.38E-104 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS20490 bce778af12934d14b6a409ad4a4e73dc 439 Gene3D G3DSA:3.20.20.140 83 364 6.5E-119 T 10-03-2017 RG49_RS20490 bce778af12934d14b6a409ad4a4e73dc 439 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 33 432 2.2E-190 T 10-03-2017 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 RG49_RS20490 bce778af12934d14b6a409ad4a4e73dc 439 Gene3D G3DSA:2.30.40.10 365 438 3.0E-7 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS14125 671c99f93c25609cc246c5d8ff3b74af 251 TIGRFAM TIGR02356 adenyl_thiF: thiazole biosynthesis adenylyltransferase ThiF 8 209 5.3E-87 T 10-03-2017 IPR012731 Thiazole biosynthesis adenylyltransferase ThiF KEGG: 00730+2.7.7.73|MetaCyc: PWY-6891|MetaCyc: PWY-6892 RG49_RS14125 671c99f93c25609cc246c5d8ff3b74af 251 SUPERFAMILY SSF69572 2 245 1.57E-81 T 10-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 RG49_RS14125 671c99f93c25609cc246c5d8ff3b74af 251 Gene3D G3DSA:3.40.50.720 3 244 2.3E-77 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14125 671c99f93c25609cc246c5d8ff3b74af 251 Pfam PF00899 ThiF family 9 240 4.7E-66 T 10-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 PIRSF PIRSF000124 1 388 1.6E-143 T 10-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 Gene3D G3DSA:3.40.50.720 1 197 5.8E-67 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 SUPERFAMILY SSF52413 283 387 8.37E-28 T 10-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 378 9.4E-103 T 10-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 Gene3D G3DSA:1.10.1040.10 198 284 8.1E-36 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 169 3.6E-32 T 10-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 281 4.0E-27 T 10-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 375 2.9E-8 T 10-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 SUPERFAMILY SSF51735 1 194 8.86E-48 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 Gene3D G3DSA:3.40.50.720 285 388 1.6E-50 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 SMART SM00984 300 387 2.2E-13 T 10-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 SUPERFAMILY SSF48179 191 287 2.21E-30 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS25060 4626c2881344f67e0e9ad7dd6d207efb 388 PIRSF PIRSF500134 1 343 3.0E-120 T 10-03-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 RG49_RS18870 2c78583efca34b5bfbb69d2a36d4f27d 174 Gene3D G3DSA:3.30.1050.10 58 135 3.1E-12 T 10-03-2017 IPR003033 SCP2 sterol-binding domain RG49_RS18870 2c78583efca34b5bfbb69d2a36d4f27d 174 SUPERFAMILY SSF55718 42 137 5.42E-22 T 10-03-2017 IPR003033 SCP2 sterol-binding domain RG49_RS18870 2c78583efca34b5bfbb69d2a36d4f27d 174 PIRSF PIRSF025550 1 173 1.5E-83 T 10-03-2017 IPR016830 Uncharacterised conserved protein UCP025550, lipid carrier protein, YhbT RG49_RS18870 2c78583efca34b5bfbb69d2a36d4f27d 174 Pfam PF02036 SCP-2 sterol transfer family 45 133 1.4E-17 T 10-03-2017 IPR003033 SCP2 sterol-binding domain RG49_RS15945 27fdf3799106cf72b1c643d77c611784 396 Pfam PF07690 Major Facilitator Superfamily 25 344 2.6E-32 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS15945 27fdf3799106cf72b1c643d77c611784 396 Gene3D G3DSA:1.20.1250.20 211 387 1.5E-8 T 10-03-2017 RG49_RS15945 27fdf3799106cf72b1c643d77c611784 396 Gene3D G3DSA:1.20.1250.20 21 204 4.6E-25 T 10-03-2017 RG49_RS15945 27fdf3799106cf72b1c643d77c611784 396 SUPERFAMILY SSF103473 14 389 1.57E-50 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15945 27fdf3799106cf72b1c643d77c611784 396 Hamap MF_01189 Purine ribonucleoside efflux pump NepI [nepI]. 1 396 48.163 T 10-03-2017 IPR023680 Purine ribonucleoside efflux pump, NepI GO:0015211|GO:0015860|GO:0016021 RG49_RS13455 0efb2f205c409ff77d8bffd76a9cc51d 315 Gene3D G3DSA:3.40.190.10 55 130 9.5E-5 T 10-03-2017 RG49_RS13455 0efb2f205c409ff77d8bffd76a9cc51d 315 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 35 277 3.7E-71 T 10-03-2017 RG49_RS13455 0efb2f205c409ff77d8bffd76a9cc51d 315 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 1 291 1.9E-113 T 10-03-2017 IPR017797 Phosphonate ABC transporter, periplasmic substrate-binding protein GO:0015604|GO:0015716|GO:0043190 RG49_RS13455 0efb2f205c409ff77d8bffd76a9cc51d 315 Gene3D G3DSA:3.40.190.10 131 221 1.0E-11 T 10-03-2017 RG49_RS13455 0efb2f205c409ff77d8bffd76a9cc51d 315 SUPERFAMILY SSF53850 54 244 1.32E-44 T 10-03-2017 RG49_RS13455 0efb2f205c409ff77d8bffd76a9cc51d 315 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 3 254 1.3E-94 T 10-03-2017 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Pfam PF08335 GlnD PII-uridylyltransferase 193 331 1.9E-36 T 10-03-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 SUPERFAMILY SSF55021 705 761 6.25E-9 T 10-03-2017 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 890 348.79 T 10-03-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 SUPERFAMILY SSF81593 213 328 1.18E-9 T 10-03-2017 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 SMART SM00471 464 611 3.1E-12 T 10-03-2017 IPR003607 HD/PDEase domain RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 SUPERFAMILY SSF81301 49 189 5.06E-21 T 10-03-2017 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Gene3D G3DSA:3.30.70.260 708 768 4.0E-4 T 10-03-2017 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Gene3D G3DSA:3.30.70.260 816 867 1.1E-7 T 10-03-2017 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Gene3D G3DSA:3.30.460.10 87 181 1.0E-6 T 10-03-2017 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 PIRSF PIRSF006288 27 889 0.0 T 10-03-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Pfam PF01909 Nucleotidyltransferase domain 86 137 1.8E-6 T 10-03-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 SUPERFAMILY SSF109604 446 628 8.0E-13 T 10-03-2017 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Pfam PF01842 ACT domain 817 874 1.2E-8 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Pfam PF01842 ACT domain 709 759 3.6E-7 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Pfam PF01966 HD domain 468 601 1.4E-14 T 10-03-2017 IPR006674 HD domain RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 Gene3D G3DSA:1.10.3210.10 438 630 2.4E-28 T 10-03-2017 IPR006674 HD domain RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 51 884 3.4E-302 T 10-03-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 RG49_RS10990 ef4b2dd86af8aab2d64baa976a7c4466 890 SUPERFAMILY SSF55021 815 874 4.2E-9 T 10-03-2017 RG49_RS12640 ba902e32a9d4926ea34f7ac2cf16c610 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 63 - T 10-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site RG49_RS12640 ba902e32a9d4926ea34f7ac2cf16c610 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.0E-12 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS12640 ba902e32a9d4926ea34f7ac2cf16c610 197 Gene3D G3DSA:1.10.10.60 9 72 4.2E-18 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS12640 ba902e32a9d4926ea34f7ac2cf16c610 197 SUPERFAMILY SSF48498 89 190 1.21E-13 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS12640 ba902e32a9d4926ea34f7ac2cf16c610 197 Gene3D G3DSA:1.10.357.10 81 192 2.6E-12 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS12640 ba902e32a9d4926ea34f7ac2cf16c610 197 SUPERFAMILY SSF46689 9 89 4.19E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS04380 fa0711f0e88339af05915ed35d143e72 543 Gene3D G3DSA:3.10.105.10 310 511 1.2E-61 T 10-03-2017 RG49_RS04380 fa0711f0e88339af05915ed35d143e72 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 463 4.1E-88 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS04380 fa0711f0e88339af05915ed35d143e72 543 SUPERFAMILY SSF53850 35 525 1.6E-146 T 10-03-2017 RG49_RS04380 fa0711f0e88339af05915ed35d143e72 543 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 108 - T 10-03-2017 IPR023765 Solute-binding protein family 5, conserved site RG49_RS04380 fa0711f0e88339af05915ed35d143e72 543 PIRSF PIRSF002741 1 543 4.9E-111 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS04380 fa0711f0e88339af05915ed35d143e72 543 Gene3D G3DSA:3.40.190.10 160 309 4.7E-56 T 10-03-2017 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 SUPERFAMILY SSF53067 2 246 5.42E-77 T 10-03-2017 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 SUPERFAMILY SSF53067 245 479 1.39E-61 T 10-03-2017 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 Gene3D G3DSA:3.30.420.40 1 243 4.2E-71 T 10-03-2017 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 Gene3D G3DSA:3.30.420.40 245 485 1.9E-54 T 10-03-2017 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 243 1.0E-75 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 252 440 3.1E-36 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 128 140 - T 10-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 TIGRFAM TIGR01312 XylB: xylulokinase 3 478 2.9E-193 T 10-03-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 RG49_RS24735 c231b3c8b3ea57d3dbd317d95abb8317 487 PIRSF PIRSF000538 1 487 1.7E-137 T 10-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 SMART SM00382 285 479 0.33 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 SMART SM00382 34 222 1.9E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 Gene3D G3DSA:3.40.50.300 6 234 4.4E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 Gene3D G3DSA:3.40.50.300 268 489 7.0E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 SUPERFAMILY SSF52540 268 489 9.67E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 Pfam PF00005 ABC transporter 279 430 9.8E-18 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 Pfam PF00005 ABC transporter 25 174 3.7E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS12750 04a6ceb9ebb47d3e501d0e250e995b7d 500 SUPERFAMILY SSF52540 9 231 3.04E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05310 633709293862f3c6a04f8b8faf23d245 215 Pfam PF04337 Protein of unknown function, DUF480 5 158 7.3E-64 T 10-03-2017 IPR007432 Protein of unknown function DUF480 RG49_RS05310 633709293862f3c6a04f8b8faf23d245 215 Hamap MF_01584 UPF0502 protein YceH [yceH]. 5 211 34.694 T 10-03-2017 IPR007432 Protein of unknown function DUF480 RG49_RS05310 633709293862f3c6a04f8b8faf23d245 215 Gene3D G3DSA:1.10.10.10 95 172 1.7E-36 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS05310 633709293862f3c6a04f8b8faf23d245 215 SUPERFAMILY SSF46785 90 172 4.19E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS05310 633709293862f3c6a04f8b8faf23d245 215 SUPERFAMILY SSF46785 2 84 1.68E-32 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS05310 633709293862f3c6a04f8b8faf23d245 215 Gene3D G3DSA:1.10.10.10 3 87 1.3E-39 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 Gene3D G3DSA:3.40.50.10490 21 192 7.2E-41 T 10-03-2017 RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 Pfam PF00571 CBS domain 282 315 5.5E-4 T 10-03-2017 IPR000644 CBS domain RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 SUPERFAMILY SSF53697 10 255 5.56E-54 T 10-03-2017 RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 PIRSF PIRSF004692 1 321 3.0E-122 T 10-03-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 Gene3D G3DSA:3.10.580.10 193 317 3.9E-30 T 10-03-2017 RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 43 311 2.3E-135 T 10-03-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 SUPERFAMILY SSF54631 260 317 3.88E-8 T 10-03-2017 RG49_RS21545 449dd5c046c85ec2a6031e6d612a4336 321 Pfam PF01380 SIS domain 39 169 2.1E-29 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 Gene3D G3DSA:1.10.10.10 6 76 6.7E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 Gene3D G3DSA:1.20.120.530 94 234 1.6E-32 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 4.9E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 4.9E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 SUPERFAMILY SSF48008 95 234 3.4E-28 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 SUPERFAMILY SSF46785 2 77 3.98E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 SMART SM00895 97 226 6.6E-22 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 3.8E-23 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 SMART SM00345 14 73 9.6E-26 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12385 70486e9a70fd07afad407569bd60334b 257 Pfam PF07729 FCD domain 97 225 1.9E-20 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS05845 d45584d250ec0dca5d34f5bd15067a15 597 Pfam PF00374 Nickel-dependent hydrogenase 54 582 6.6E-221 T 10-03-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 RG49_RS05845 d45584d250ec0dca5d34f5bd15067a15 597 Gene3D G3DSA:1.10.645.10 15 582 1.4E-224 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05845 d45584d250ec0dca5d34f5bd15067a15 597 SUPERFAMILY SSF56762 12 582 6.67E-168 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05845 d45584d250ec0dca5d34f5bd15067a15 597 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 54 79 - T 10-03-2017 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 RG49_RS05845 d45584d250ec0dca5d34f5bd15067a15 597 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 573 582 - T 10-03-2017 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 Pfam PF00294 pfkB family carbohydrate kinase 5 300 1.9E-70 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 PRINTS PR00990 Ribokinase signature 185 200 8.6E-6 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 PRINTS PR00990 Ribokinase signature 36 55 8.6E-6 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 PRINTS PR00990 Ribokinase signature 224 235 8.6E-6 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 Gene3D G3DSA:3.40.1190.20 3 312 2.1E-71 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 41 65 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 SUPERFAMILY SSF53613 1 300 1.71E-69 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS01125 da2f55b890468722563c54ebbbd8fd66 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS23155 4cc6367ba3526a3be10334ec7067599c 114 Pfam PF07037 Putative transcription regulator (DUF1323) 1 113 2.1E-49 T 10-03-2017 IPR010749 Protein of unknown function DUF1323 RG49_RS23155 4cc6367ba3526a3be10334ec7067599c 114 ProDom PD060594 TRANSCRIPTION YFED YFEC DNA-BINDING REGULATION NEGATIVE REGULATOR STY2653 ECS3274 STY2652 1 114 9.0E-61 T 10-03-2017 IPR010749 Protein of unknown function DUF1323 RG49_RS23155 4cc6367ba3526a3be10334ec7067599c 114 Gene3D G3DSA:1.10.10.10 1 61 2.2E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23155 4cc6367ba3526a3be10334ec7067599c 114 SUPERFAMILY SSF46955 1 57 1.28E-12 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 16 300 42.141 T 10-03-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 19 284 6.7E-47 T 10-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 SUPERFAMILY SSF52374 16 296 1.63E-87 T 10-03-2017 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 Gene3D G3DSA:3.40.50.620 14 158 6.1E-39 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 Gene3D G3DSA:3.40.50.620 170 299 9.9E-23 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 31 6.8E-14 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 6.8E-14 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 44 6.8E-14 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 PRINTS PR00987 Glutamyl-tRNA synthetase signature 48 61 6.8E-14 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 6.8E-14 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS11110 4d6de3381ec7521ca6b2e2701ac8d9fd 308 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 16 281 1.5E-114 T 10-03-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 SUPERFAMILY SSF53850 88 294 1.09E-41 T 10-03-2017 RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 1.5E-12 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 Gene3D G3DSA:1.10.10.10 2 81 1.3E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 Gene3D G3DSA:3.40.190.10 180 260 7.8E-21 T 10-03-2017 RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.9E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.9E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.9E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 SUPERFAMILY SSF46785 11 112 2.29E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 Pfam PF03466 LysR substrate binding domain 90 293 8.9E-41 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS25335 f32230823bba99fb61ee6f264443f01b 316 Gene3D G3DSA:3.40.190.10 92 179 4.1E-21 T 10-03-2017 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 Gene3D G3DSA:3.30.70.270 67 157 1.9E-26 T 10-03-2017 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 Gene3D G3DSA:3.30.1490.100 249 354 3.6E-5 T 10-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 Pfam PF11799 impB/mucB/samB family C-terminal domain 243 351 1.0E-10 T 10-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 SUPERFAMILY SSF100879 250 346 1.96E-5 T 10-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 Gene3D G3DSA:1.10.150.20 170 240 3.1E-23 T 10-03-2017 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 SUPERFAMILY SSF56672 1 237 7.47E-73 T 10-03-2017 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 Pfam PF11798 IMS family HHH motif 172 200 2.4E-6 T 10-03-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 Pfam PF00817 impB/mucB/samB family 5 150 1.3E-38 T 10-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS04740 ea74013e7d1b8c36b0e126e8beac125b 422 Pfam PF13438 Domain of unknown function (DUF4113) 371 421 1.6E-21 T 10-03-2017 IPR025188 Domain of unknown function DUF4113 RG49_RS02455 210a9ac471222719d08108159361b17b 247 SUPERFAMILY SSF102712 6 97 1.96E-16 T 10-03-2017 RG49_RS02455 210a9ac471222719d08108159361b17b 247 Pfam PF14464 Prokaryotic homologs of the JAB domain 3 98 8.8E-14 T 10-03-2017 IPR028090 JAB domain, prokaryotic RG49_RS02455 210a9ac471222719d08108159361b17b 247 Gene3D G3DSA:3.90.1720.10 115 227 2.7E-16 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS02455 210a9ac471222719d08108159361b17b 247 Gene3D G3DSA:3.40.140.10 5 114 4.0E-18 T 10-03-2017 RG49_RS02455 210a9ac471222719d08108159361b17b 247 SMART SM00232 1 119 0.0021 T 10-03-2017 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 RG49_RS02455 210a9ac471222719d08108159361b17b 247 SUPERFAMILY SSF54001 101 228 2.55E-16 T 10-03-2017 RG49_RS02455 210a9ac471222719d08108159361b17b 247 Pfam PF00877 NlpC/P60 family 111 223 3.0E-13 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS00985 28005f2d24b9d325cb9f814a18526ab9 212 PIRSF PIRSF006324 4 212 7.5E-65 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS00985 28005f2d24b9d325cb9f814a18526ab9 212 Pfam PF01810 LysE type translocator 18 209 2.0E-59 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS24470 a5e5c5aa3a79360423d06fbe0b5e93d7 315 Pfam PF01207 Dihydrouridine synthase (Dus) 5 306 6.7E-96 T 10-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS24470 a5e5c5aa3a79360423d06fbe0b5e93d7 315 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 310 51.907 T 10-03-2017 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 RG49_RS24470 a5e5c5aa3a79360423d06fbe0b5e93d7 315 SUPERFAMILY SSF51395 1 302 1.61E-70 T 10-03-2017 RG49_RS24470 a5e5c5aa3a79360423d06fbe0b5e93d7 315 PIRSF PIRSF006621 1 315 4.3E-83 T 10-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS24470 a5e5c5aa3a79360423d06fbe0b5e93d7 315 Gene3D G3DSA:3.20.20.70 2 240 4.7E-63 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS24470 a5e5c5aa3a79360423d06fbe0b5e93d7 315 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 10-03-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS11930 b9287a396936572817b1db247faaae97 215 Hamap MF_01040 Probable phosphoglycerate mutase GpmB [gpmB]. 1 215 65.638 T 10-03-2017 IPR023086 Phosphoglycerate mutase, GpmB, probable GO:0004619|GO:0006096 RG49_RS11930 b9287a396936572817b1db247faaae97 215 SMART SM00855 3 157 4.3E-24 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS11930 b9287a396936572817b1db247faaae97 215 SUPERFAMILY SSF53254 1 208 3.4E-58 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS11930 b9287a396936572817b1db247faaae97 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 194 1.8E-57 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS11930 b9287a396936572817b1db247faaae97 215 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 10-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 RG49_RS11930 b9287a396936572817b1db247faaae97 215 Gene3D G3DSA:3.40.50.1240 2 209 6.0E-61 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS24245 882b23dd4426ba4507b22747798f12cb 114 ProDom PD073777 YEJG CYTOPLASMIC SIMILAR Y2914 YPO1269 STY2456 ECS3073 ESCHERICHIA COLI 1 114 2.0E-62 T 10-03-2017 IPR020489 Uncharacterised protein family YejG RG49_RS24245 882b23dd4426ba4507b22747798f12cb 114 Pfam PF13989 YejG-like protein 4 108 1.5E-48 T 10-03-2017 IPR020489 Uncharacterised protein family YejG RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 125 289 2.5E-54 T 10-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 SUPERFAMILY SSF82866 79 303 6.41E-39 T 10-03-2017 RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 PRINTS PR01755 Bacterial translocase SecF protein signature 44 59 1.3E-30 T 10-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 PRINTS PR01755 Bacterial translocase SecF protein signature 208 226 1.3E-30 T 10-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 PRINTS PR01755 Bacterial translocase SecF protein signature 160 174 1.3E-30 T 10-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 PRINTS PR01755 Bacterial translocase SecF protein signature 240 255 1.3E-30 T 10-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 Gene3D G3DSA:1.20.1640.10 140 305 4.6E-24 T 10-03-2017 RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 Pfam PF07549 SecD/SecF GG Motif 39 66 1.5E-11 T 10-03-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 17 303 28.189 T 10-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 Pfam PF02355 Protein export membrane protein 117 301 1.8E-69 T 10-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial RG49_RS09085 6f0f70b2ec5ace4d18481c7117b55854 323 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 45 292 1.9E-87 T 10-03-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 RG49_RS04085 c7cf9937eba6d834978ea868779e2a73 321 SUPERFAMILY SSF161098 72 138 4.45E-23 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04085 c7cf9937eba6d834978ea868779e2a73 321 SUPERFAMILY SSF161098 178 300 4.45E-23 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04085 c7cf9937eba6d834978ea868779e2a73 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 311 1.8E-44 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04085 c7cf9937eba6d834978ea868779e2a73 321 Gene3D G3DSA:1.10.3720.10 181 305 2.1E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04085 c7cf9937eba6d834978ea868779e2a73 321 Gene3D G3DSA:1.10.3720.10 72 141 2.1E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 Gene3D G3DSA:1.20.1560.10 13 325 5.6E-71 T 10-03-2017 RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 Gene3D G3DSA:3.40.50.300 342 574 2.0E-86 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 SMART SM00382 368 555 1.4E-17 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 SUPERFAMILY SSF52540 332 580 1.04E-96 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 SUPERFAMILY SSF90123 8 325 3.53E-75 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 Pfam PF00005 ABC transporter 359 509 1.5E-35 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 Pfam PF00664 ABC transporter transmembrane region 27 297 3.6E-61 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS06165 bb4f3221a11faf89b813e5b68603aa1e 582 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 12 581 1.0E-275 T 10-03-2017 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 Gene3D G3DSA:3.90.180.10 6 188 1.1E-48 T 10-03-2017 IPR011032 GroES-like RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 Gene3D G3DSA:3.40.50.720 189 308 8.0E-30 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 39 153 6.5E-29 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 Pfam PF00107 Zinc-binding dehydrogenase 196 323 2.2E-25 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 SUPERFAMILY SSF51735 159 318 3.71E-35 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 SMART SM00829 22 360 6.7E-7 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 SUPERFAMILY SSF50129 333 361 1.98E-43 T 10-03-2017 IPR011032 GroES-like RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 SUPERFAMILY SSF50129 10 163 1.98E-43 T 10-03-2017 IPR011032 GroES-like RG49_RS22345 f4eacb759993c67665273b59ea25db40 364 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 80 94 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 74 325 6.7E-31 T 10-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 Pfam PF05683 Fumarase C-terminus 332 537 1.4E-94 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 PIRSF PIRSF001394 30 548 3.8E-239 T 10-03-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 Gene3D G3DSA:3.20.130.10 348 537 2.6E-76 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 Pfam PF05681 Fumarate hydratase (Fumerase) 51 326 2.1E-86 T 10-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 373 537 2.0E-62 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 ProSitePatterns PS00163 Fumarate lyases signature. 456 465 - T 10-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 RG49_RS02000 de6f60430b310db5b498f9c0d4a4d943 548 SUPERFAMILY SSF117457 361 536 3.14E-62 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS07825 f8229ee49d6b3219cae09be5df2b8c13 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 271 3.8E-48 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS07825 f8229ee49d6b3219cae09be5df2b8c13 302 Gene3D G3DSA:3.40.190.10 38 126 2.6E-31 T 10-03-2017 RG49_RS07825 f8229ee49d6b3219cae09be5df2b8c13 302 Gene3D G3DSA:3.40.190.10 234 276 2.6E-31 T 10-03-2017 RG49_RS07825 f8229ee49d6b3219cae09be5df2b8c13 302 SUPERFAMILY SSF53850 8 274 2.88E-64 T 10-03-2017 RG49_RS07825 f8229ee49d6b3219cae09be5df2b8c13 302 Gene3D G3DSA:3.40.190.10 127 233 1.1E-31 T 10-03-2017 RG49_RS07825 f8229ee49d6b3219cae09be5df2b8c13 302 SMART SM00062 41 273 5.6E-72 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 PIRSF PIRSF000371 1 287 3.9E-97 T 10-03-2017 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 Gene3D G3DSA:3.80.30.10 113 278 1.2E-43 T 10-03-2017 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 SUPERFAMILY SSF102114 79 259 4.32E-14 T 10-03-2017 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 10-03-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 SUPERFAMILY SSF54862 43 126 1.61E-15 T 10-03-2017 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 TIGRFAM TIGR04041 activase_YjjW: glycine radical enzyme activase, YjjW family 5 281 5.3E-120 T 10-03-2017 IPR023912 Putative glycyl-radical enzyme activating enzyme YjjW RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 Pfam PF13353 4Fe-4S single cluster domain 17 169 4.6E-9 T 10-03-2017 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 Pfam PF04055 Radical SAM superfamily 27 232 6.1E-25 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 Gene3D G3DSA:3.30.70.20 45 98 2.2E-13 T 10-03-2017 RG49_RS12025 0a562be46805cf5cef55e4c0c1c03bc3 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 76 87 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS03620 d2266979c3adfda1392b87646a2f415d 165 SUPERFAMILY SSF53955 10 163 1.02E-54 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS03620 d2266979c3adfda1392b87646a2f415d 165 Pfam PF00959 Phage lysozyme 48 154 7.4E-33 T 10-03-2017 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 RG49_RS03620 d2266979c3adfda1392b87646a2f415d 165 Gene3D G3DSA:1.10.530.40 34 163 1.7E-54 T 10-03-2017 IPR023347 Lysozyme domain GO:0003796 RG49_RS20205 3ba845c9be72bc9c13e72f5f445d2750 306 SUPERFAMILY SSF52768 13 301 2.88E-91 T 10-03-2017 RG49_RS20205 3ba845c9be72bc9c13e72f5f445d2750 306 PIRSF PIRSF036979 12 304 1.1E-101 T 10-03-2017 IPR006035 Ureohydrolase GO:0046872 RG49_RS20205 3ba845c9be72bc9c13e72f5f445d2750 306 Pfam PF00491 Arginase family 34 297 7.7E-86 T 10-03-2017 IPR006035 Ureohydrolase GO:0046872 RG49_RS20205 3ba845c9be72bc9c13e72f5f445d2750 306 Gene3D G3DSA:3.40.800.10 11 302 3.5E-97 T 10-03-2017 IPR023696 Ureohydrolase domain RG49_RS20205 3ba845c9be72bc9c13e72f5f445d2750 306 ProSitePatterns PS01053 Arginase family signature. 228 249 - T 10-03-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 RG49_RS20205 3ba845c9be72bc9c13e72f5f445d2750 306 TIGRFAM TIGR01230 agmatinase: agmatinase 22 299 3.9E-119 T 10-03-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 RG49_RS20205 3ba845c9be72bc9c13e72f5f445d2750 306 Hamap MF_01418 Agmatinase [speB]. 1 304 70.587 T 10-03-2017 IPR023694 Agmatinase GO:0008783|GO:0009446|GO:0030145 KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 22 485 38.792 T 10-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 SUPERFAMILY SSF48179 210 370 4.25E-42 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 368 1.1E-137 T 10-03-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 Gene3D G3DSA:3.40.50.720 1 201 2.6E-76 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 1.4E-58 T 10-03-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 Gene3D G3DSA:1.10.1040.10 361 481 1.1E-15 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 SUPERFAMILY SSF48179 349 484 9.52E-40 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 SUPERFAMILY SSF51735 30 209 5.42E-58 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 357 482 4.2E-21 T 10-03-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 RG49_RS15345 c9a3ff3d57da59c58e00846dfb3dcc5c 491 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 342 1.4E-28 T 10-03-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 RG49_RS23505 280c609c885bd4731710722942144c15 422 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 413 5.5E-115 T 10-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 SUPERFAMILY SSF53623 13 284 3.05E-89 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 52 75 - T 10-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 Gene3D G3DSA:3.90.190.20 288 415 1.6E-46 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 Pfam PF02875 Mur ligase family, glutamate ligase domain 287 346 8.6E-7 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 144 159 - T 10-03-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 PIRSF PIRSF001563 6 419 1.6E-108 T 10-03-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 Gene3D G3DSA:3.40.1190.10 10 284 4.2E-93 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 SUPERFAMILY SSF53244 286 414 4.58E-34 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS23505 280c609c885bd4731710722942144c15 422 Pfam PF08245 Mur ligase middle domain 54 197 2.2E-10 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Pfam PF01568 Molydopterin dinucleotide binding domain 1087 1199 4.4E-20 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:3.40.50.740 108 117 8.9E-4 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:3.40.50.740 149 205 8.9E-4 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:3.90.55.10 779 833 3.7E-7 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 SMART SM00926 43 105 1.9E-7 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:2.20.25.90 52 98 1.0E-31 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 10-03-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:4.10.1200.10 1 28 5.6E-19 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 SUPERFAMILY SSF50692 1082 1235 1.42E-45 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 SUPERFAMILY SSF53706 5 1070 0.0 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:3.40.228.10 218 336 1.2E-76 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:3.40.228.10 486 591 1.2E-76 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1124 1151 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 4 40 1.4E-16 T 10-03-2017 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:2.40.40.20 1054 1233 1.6E-43 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 776 793 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Gene3D G3DSA:3.40.50.740 592 778 4.3E-60 T 10-03-2017 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1234 0.0 T 10-03-2017 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS03020 23512ae9024e7b50589304b87a991ba1 1246 Pfam PF00384 Molybdopterin oxidoreductase 108 832 4.8E-166 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS16315 05afc641074561bb7c3cff9689e350ff 398 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 5 397 1.4E-225 T 10-03-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 RG49_RS16315 05afc641074561bb7c3cff9689e350ff 398 Gene3D G3DSA:3.40.640.10 58 278 2.3E-96 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS16315 05afc641074561bb7c3cff9689e350ff 398 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 10-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 RG49_RS16315 05afc641074561bb7c3cff9689e350ff 398 SUPERFAMILY SSF53383 5 396 2.96E-127 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS16315 05afc641074561bb7c3cff9689e350ff 398 Gene3D G3DSA:3.90.1150.10 279 393 9.9E-36 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS16315 05afc641074561bb7c3cff9689e350ff 398 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 395 54.128 T 10-03-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 RG49_RS16315 05afc641074561bb7c3cff9689e350ff 398 Pfam PF00155 Aminotransferase class I and II 43 387 1.1E-79 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS20065 6a9474d1a403fb0632e61ac51a8301a8 360 Hamap MF_01616 Membrane-bound lytic murein transglycosylase C [mltC]. 2 359 66.899 T 10-03-2017 IPR023664 Murein transglycosylase-C GO:0009279|GO:0016798|GO:0016998 RG49_RS20065 6a9474d1a403fb0632e61ac51a8301a8 360 Gene3D G3DSA:1.10.530.10 188 359 3.3E-41 T 10-03-2017 RG49_RS20065 6a9474d1a403fb0632e61ac51a8301a8 360 SUPERFAMILY SSF53955 192 358 1.24E-36 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS20065 6a9474d1a403fb0632e61ac51a8301a8 360 Pfam PF01464 Transglycosylase SLT domain 197 320 1.3E-32 T 10-03-2017 IPR008258 Transglycosylase SLT domain 1 RG49_RS20065 6a9474d1a403fb0632e61ac51a8301a8 360 Pfam PF11873 Domain of unknown function (DUF3393) 4 192 1.9E-76 T 10-03-2017 IPR024570 Murein transglycosylase-C, N-terminal RG49_RS20065 6a9474d1a403fb0632e61ac51a8301a8 360 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 214 242 - T 10-03-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 RG49_RS24920 d6a0ba6bed90c6f7d54a08c3fbbcd213 373 SUPERFAMILY SSF51735 2 353 4.28E-90 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24920 d6a0ba6bed90c6f7d54a08c3fbbcd213 373 Gene3D G3DSA:3.90.25.10 206 247 1.1E-52 T 10-03-2017 RG49_RS24920 d6a0ba6bed90c6f7d54a08c3fbbcd213 373 Gene3D G3DSA:3.90.25.10 304 363 1.1E-52 T 10-03-2017 RG49_RS24920 d6a0ba6bed90c6f7d54a08c3fbbcd213 373 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 356 56.612 T 10-03-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 RG49_RS24920 d6a0ba6bed90c6f7d54a08c3fbbcd213 373 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 346 9.9E-162 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24920 d6a0ba6bed90c6f7d54a08c3fbbcd213 373 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 353 3.1E-177 T 10-03-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 RG49_RS24920 d6a0ba6bed90c6f7d54a08c3fbbcd213 373 Gene3D G3DSA:3.40.50.720 4 205 8.6E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.1E-21 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 SMART SM00354 1 71 2.8E-36 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 Gene3D G3DSA:3.40.50.2300 167 330 3.8E-52 T 10-03-2017 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 SUPERFAMILY SSF53822 60 333 1.02E-84 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 Gene3D G3DSA:3.40.50.2300 58 166 7.4E-45 T 10-03-2017 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 SUPERFAMILY SSF47413 1 59 1.56E-16 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.6E-7 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.6E-7 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 Gene3D G3DSA:1.10.260.40 2 57 2.6E-24 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 Pfam PF13377 Periplasmic binding protein-like domain 168 329 5.1E-36 T 10-03-2017 RG49_RS20840 5ecc3e5982945c7eb445da4c620dac51 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 10-03-2017 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 423 563 1.5E-36 T 10-03-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 321 424 5.2E-22 T 10-03-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 56 410 5.5E-183 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 297 313 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 313 332 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 213 239 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 247 267 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 277 297 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 135 152 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 83 109 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 162 184 4.4E-72 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 Pfam PF01578 Cytochrome C assembly protein 92 299 5.4E-49 T 10-03-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 342 360 7.4E-40 T 10-03-2017 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 376 388 7.4E-40 T 10-03-2017 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 559 572 7.4E-40 T 10-03-2017 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 446 465 7.4E-40 T 10-03-2017 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS13630 be79815abf1286379b4a03b045ef5f92 572 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 321 336 7.4E-40 T 10-03-2017 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 SUPERFAMILY SSF55347 155 317 1.13E-57 T 10-03-2017 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 4 328 3.0E-199 T 10-03-2017 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 155 2.4E-54 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 5.4E-30 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 5.4E-30 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 5.4E-30 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 5.4E-30 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 5.4E-30 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 SMART SM00846 3 155 3.5E-83 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 Gene3D G3DSA:3.40.50.720 1 163 6.4E-67 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 Hamap MF_01640 D-erythrose-4-phosphate dehydrogenase [epd]. 2 337 66.378 T 10-03-2017 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 Gene3D G3DSA:3.30.360.10 164 318 1.7E-61 T 10-03-2017 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 10-03-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 PIRSF PIRSF000149 1 338 3.1E-135 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 2.2E-54 T 10-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20255 e0183ec78b17e4f81371cbead6b912d1 339 SUPERFAMILY SSF51735 1 179 5.34E-57 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 Gene3D G3DSA:3.50.50.60 4 104 2.0E-18 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 8.2E-20 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 8.2E-20 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.2E-20 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 8.2E-20 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 8.2E-20 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 7.4E-14 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 7.4E-14 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.4E-14 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 7.4E-14 T 10-03-2017 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 SUPERFAMILY SSF51905 5 301 2.14E-34 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 278 1.2E-51 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 Hamap MF_01313 Nitric oxide reductase FlRd-NAD(+) reductase [norW]. 1 377 55.993 T 10-03-2017 IPR023961 Nitric oxide reductase FlRd-NAD(+) reductase GO:0016731|GO:0055114 RG49_RS21530 75e256b131bdff02eb1adbd887fffb5f 377 Gene3D G3DSA:3.50.50.60 105 300 2.7E-44 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 SUPERFAMILY SSF53720 4 482 1.44E-172 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 Hamap MF_00804 NAD/NADP-dependent betaine aldehyde dehydrogenase [betB]. 4 490 58.022 T 10-03-2017 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 Pfam PF00171 Aldehyde dehydrogenase family 17 479 1.1E-179 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 10 477 1.6E-248 T 10-03-2017 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 Gene3D G3DSA:3.40.605.10 6 265 6.7E-104 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS09620 49fcbbfa7b0d959af14afbe967b8c19b 490 Gene3D G3DSA:3.40.309.10 266 444 1.4E-69 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 SUPERFAMILY SSF51735 91 257 3.09E-33 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 Pfam PF11890 Domain of unknown function (DUF3410) 289 369 8.2E-28 T 10-03-2017 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 256 2.1E-32 T 10-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 SUPERFAMILY SSF52283 4 109 1.51E-18 T 10-03-2017 RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 Gene3D G3DSA:3.40.50.720 110 259 1.5E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 357 47.903 T 10-03-2017 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 197 213 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 119 146 - T 10-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 Gene3D G3DSA:3.40.50.720 2 109 2.0E-24 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23480 a0f73ae332a852ab3e424f9823441b61 378 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 281 4.6E-18 T 10-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 RG49_RS13185 812912794cc80a1be6472a871e11a1e4 41 Pfam PF08085 Entericidin EcnA/B family 20 40 1.8E-7 T 10-03-2017 IPR012556 Entericidin A/B GO:0009636|GO:0016020 RG49_RS07080 7594e119ffe8456710f27d137885e84c 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 13 244 1.8E-22 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS07080 7594e119ffe8456710f27d137885e84c 253 Gene3D G3DSA:3.60.10.10 3 251 5.5E-25 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS07080 7594e119ffe8456710f27d137885e84c 253 SUPERFAMILY SSF56219 8 251 9.29E-55 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 SMART SM00422 12 80 1.2E-22 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 Gene3D G3DSA:1.10.1660.10 10 65 3.2E-18 T 10-03-2017 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 12 152 4.7E-75 T 10-03-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 Pfam PF00376 MerR family regulatory protein 13 49 1.4E-13 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 Pfam PF09278 MerR, DNA binding 54 119 8.7E-15 T 10-03-2017 IPR015358 Transcription regulator MerR, DNA binding RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 SUPERFAMILY SSF46955 12 134 2.16E-27 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 Gene3D G3DSA:1.10.1660.10 66 144 7.0E-14 T 10-03-2017 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 5.9E-11 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 24 5.9E-11 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS13705 a1a3f0ca97e2d301588bead4f4b7ffac 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 24 37 5.9E-11 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS03610 b75489a56d800b5c4545e0a061c54090 485 Pfam PF02386 Cation transport protein 40 479 4.9E-129 T 10-03-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 RG49_RS03610 b75489a56d800b5c4545e0a061c54090 485 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 86 468 5.6E-125 T 10-03-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 RG49_RS03610 b75489a56d800b5c4545e0a061c54090 485 PIRSF PIRSF006247 1 485 1.1E-171 T 10-03-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 Pfam PF02110 Hydroxyethylthiazole kinase family 15 259 5.0E-107 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 15 261 9.8E-103 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 36 57 5.1E-43 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 167 184 5.1E-43 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 67 75 5.1E-43 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 93 110 5.1E-43 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 123 137 5.1E-43 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 23 30 5.1E-43 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 17 262 30.224 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 Gene3D G3DSA:3.40.1190.20 9 260 4.6E-87 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 SUPERFAMILY SSF53613 12 260 3.27E-61 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24665 0524d22822fb3638d60f55dce358b8e5 262 PIRSF PIRSF000513 9 262 1.9E-106 T 10-03-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS15020 2689b905d6a0de9bb235c08cee857bf8 251 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 36 51 - T 10-03-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 RG49_RS15020 2689b905d6a0de9bb235c08cee857bf8 251 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 25 250 1.3E-89 T 10-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 RG49_RS15020 2689b905d6a0de9bb235c08cee857bf8 251 Pfam PF01209 ubiE/COQ5 methyltransferase family 15 250 1.2E-113 T 10-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 RG49_RS15020 2689b905d6a0de9bb235c08cee857bf8 251 Gene3D G3DSA:3.40.50.150 23 247 1.6E-60 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS15020 2689b905d6a0de9bb235c08cee857bf8 251 SUPERFAMILY SSF53335 18 249 3.87E-53 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS15020 2689b905d6a0de9bb235c08cee857bf8 251 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 16 250 39.601 T 10-03-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 RG49_RS15020 2689b905d6a0de9bb235c08cee857bf8 251 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 158 172 - T 10-03-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Gene3D G3DSA:2.60.40.10 113 220 1.3E-41 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Gene3D G3DSA:2.60.40.10 14 104 1.4E-20 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 125 207 7.6E-26 T 10-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 PIRSF PIRSF000463 6 728 3.1E-284 T 10-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 SMART SM00642 247 596 2.7E-6 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 SUPERFAMILY SSF81296 117 223 2.62E-35 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Gene3D G3DSA:2.60.40.1180 624 725 4.5E-37 T 10-03-2017 IPR013780 Glycosyl hydrolase, all-beta RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 SUPERFAMILY SSF51445 228 621 1.67E-110 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 628 725 7.8E-24 T 10-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 SUPERFAMILY SSF81296 16 115 1.52E-18 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 109 723 0.0 T 10-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 101 726 43.81 T 10-03-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 SUPERFAMILY SSF51011 623 726 3.51E-35 T 10-03-2017 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Gene3D G3DSA:3.20.20.80 242 610 5.5E-90 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS17410 1574ddaa23449e41981bbcae89c9f687 728 Pfam PF00128 Alpha amylase, catalytic domain 273 343 3.8E-8 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 SUPERFAMILY SSF52821 165 278 3.01E-33 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 Pfam PF00581 Rhodanese-like domain 9 128 1.8E-18 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 Pfam PF00581 Rhodanese-like domain 165 270 1.5E-13 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 259 269 - T 10-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 SUPERFAMILY SSF52821 1 152 1.57E-41 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 SMART SM00450 155 275 1.1E-24 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 SMART SM00450 7 132 9.3E-28 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 Gene3D G3DSA:3.40.250.10 1 151 1.7E-47 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 Gene3D G3DSA:3.40.250.10 152 278 4.3E-42 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS22465 0749bf7dd4e705faeea83da9bb5b3937 281 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 10-03-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 RG49_RS15255 2337f5cf3c1ec289033600991b512358 376 Gene3D G3DSA:3.90.1150.10 251 375 1.6E-20 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS15255 2337f5cf3c1ec289033600991b512358 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 371 3.2E-85 T 10-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase RG49_RS15255 2337f5cf3c1ec289033600991b512358 376 Hamap MF_02026 dTDP-4-amino-4,6-dideoxygalactose transaminase [wecE]. 1 376 78.472 T 10-03-2017 IPR032894 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE GO:0009246|GO:0019180 MetaCyc: PWY-7315 RG49_RS15255 2337f5cf3c1ec289033600991b512358 376 SUPERFAMILY SSF53383 2 375 1.88E-101 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS15255 2337f5cf3c1ec289033600991b512358 376 PIRSF PIRSF000390 1 376 9.1E-122 T 10-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase RG49_RS15255 2337f5cf3c1ec289033600991b512358 376 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 1 376 1.5E-222 T 10-03-2017 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 RG49_RS15255 2337f5cf3c1ec289033600991b512358 376 Gene3D G3DSA:3.40.640.10 1 248 2.4E-79 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS08310 af77b13732daff2b30dc54da57dc0336 457 Pfam PF02321 Outer membrane efflux protein 274 455 1.8E-28 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS08310 af77b13732daff2b30dc54da57dc0336 457 Pfam PF02321 Outer membrane efflux protein 64 247 1.6E-22 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS08310 af77b13732daff2b30dc54da57dc0336 457 SUPERFAMILY SSF56954 4 457 2.35E-103 T 10-03-2017 RG49_RS08310 af77b13732daff2b30dc54da57dc0336 457 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 457 2.8E-113 T 10-03-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 RG49_RS08310 af77b13732daff2b30dc54da57dc0336 457 Gene3D G3DSA:1.20.1600.10 53 457 4.4E-106 T 10-03-2017 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 Gene3D G3DSA:1.10.287.130 231 298 3.3E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 SMART SM00388 236 302 8.1E-15 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 SMART SM00387 348 449 9.2E-21 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 Gene3D G3DSA:3.30.565.10 310 448 5.7E-29 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 SUPERFAMILY SSF47384 219 301 1.96E-15 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 442 2.2E-16 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 Pfam PF08521 Two-component sensor kinase N-terminal 23 158 3.6E-8 T 10-03-2017 IPR013727 Two-component sensor kinase, N-terminal RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 301 3.6E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 SUPERFAMILY SSF55874 291 447 1.18E-29 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 3.5E-5 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 3.5E-5 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 Gene3D G3DSA:1.20.5.1040 2 84 3.8E-26 T 10-03-2017 RG49_RS19620 7e239e0da9f826630c337cc62cbd52bd 449 Gene3D G3DSA:1.20.5.1040 101 185 2.1E-33 T 10-03-2017 RG49_RS23010 ded884cbdc1ad9162fd1f7548b7f6267 291 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 2 275 7.3E-116 T 10-03-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 RG49_RS23010 ded884cbdc1ad9162fd1f7548b7f6267 291 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 19 276 4.2E-112 T 10-03-2017 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 RG49_RS23010 ded884cbdc1ad9162fd1f7548b7f6267 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 275 1.9E-16 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23010 ded884cbdc1ad9162fd1f7548b7f6267 291 Gene3D G3DSA:1.10.3720.10 19 281 1.7E-48 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23010 ded884cbdc1ad9162fd1f7548b7f6267 291 SUPERFAMILY SSF161098 16 268 3.92E-52 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 Pfam PF00154 recA bacterial DNA recombination protein 9 270 1.9E-142 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 2.0E-173 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 SMART SM00382 59 230 4.5E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 Gene3D G3DSA:3.40.50.300 28 269 2.0E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 ProSitePatterns PS00321 recA signature. 215 223 - T 10-03-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 SUPERFAMILY SSF52540 6 269 6.57E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 SUPERFAMILY SSF54752 272 327 4.58E-21 T 10-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 Hamap MF_00268 Protein RecA [recA]. 7 331 50.992 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 Gene3D G3DSA:3.30.250.10 272 328 5.4E-28 T 10-03-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 PRINTS PR00142 RecA protein signature 129 158 4.8E-84 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 PRINTS PR00142 RecA protein signature 212 240 4.8E-84 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 PRINTS PR00142 RecA protein signature 299 316 4.8E-84 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 PRINTS PR00142 RecA protein signature 167 196 4.8E-84 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 PRINTS PR00142 RecA protein signature 245 274 4.8E-84 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS21590 ff9f96d7f45619daca23a25a01e0c64d 353 PRINTS PR00142 RecA protein signature 95 124 4.8E-84 T 10-03-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 SUPERFAMILY SSF53383 929 951 1.06E-100 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 SUPERFAMILY SSF53383 480 889 1.06E-100 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 SUPERFAMILY SSF53383 17 440 1.82E-96 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 Gene3D G3DSA:3.40.640.10 504 779 2.9E-43 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 Gene3D G3DSA:3.40.640.10 93 305 4.7E-15 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 Pfam PF02347 Glycine cleavage system P-protein 16 440 5.8E-194 T 10-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 Pfam PF02347 Glycine cleavage system P-protein 479 739 7.5E-9 T 10-03-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 17 950 0.0 T 10-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 RG49_RS20390 0706900838e104bcede8f9e2cfdb8d2f 957 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 8 956 25.715 T 10-03-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Gene3D G3DSA:3.30.70.100 49 112 7.7E-20 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 SUPERFAMILY SSF56784 491 726 6.48E-51 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 SUPERFAMILY SSF56784 433 452 6.48E-51 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Gene3D G3DSA:3.40.1110.10 448 555 3.7E-22 T 10-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Gene3D G3DSA:2.70.150.10 186 334 6.2E-25 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 183 728 2.5E-181 T 10-03-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Pfam PF00702 haloacid dehalogenase-like hydrolase 433 639 6.9E-36 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Gene3D G3DSA:3.40.50.1000 407 447 1.7E-41 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Gene3D G3DSA:3.40.50.1000 556 692 1.7E-41 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 183 730 1.4E-164 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 626 642 1.4E-5 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 599 615 1.4E-5 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 657 682 1.4E-5 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 585 4.3E-28 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 283 297 4.3E-28 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 564 4.3E-28 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 448 4.3E-28 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 661 4.3E-28 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 645 4.3E-28 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 SUPERFAMILY SSF81665 675 714 5.49E-18 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 SUPERFAMILY SSF81665 334 428 5.49E-18 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 SUPERFAMILY SSF81665 186 237 5.49E-18 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 436 442 - T 10-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 206 705 7.3E-79 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 SUPERFAMILY SSF81653 236 333 4.18E-21 T 10-03-2017 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 ProSitePatterns PS01047 Heavy-metal-associated domain. 54 83 - T 10-03-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 SUPERFAMILY SSF55008 49 111 5.5E-16 T 10-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Pfam PF00122 E1-E2 ATPase 204 425 2.6E-59 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS17225 2aa0ef679f09628a20f90c8c936d0899 732 Pfam PF00403 Heavy-metal-associated domain 53 109 1.8E-11 T 10-03-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 RG49_RS04055 5f832b8e4ebdda24789362e2b7af8314 254 SUPERFAMILY SSF52317 23 246 4.43E-39 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS04055 5f832b8e4ebdda24789362e2b7af8314 254 Gene3D G3DSA:3.40.50.880 6 247 2.9E-52 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS04055 5f832b8e4ebdda24789362e2b7af8314 254 Pfam PF07722 Peptidase C26 8 224 4.8E-68 T 10-03-2017 IPR011697 Peptidase C26 GO:0006541|GO:0016787 RG49_RS15845 ea3bb3b2b3d8f47b24456920edfefe29 115 Pfam PF02656 Domain of unknown function (DUF202) 13 79 1.2E-15 T 10-03-2017 IPR003807 Domain of unknown function DUF202 RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 Hamap MF_01524 Probable crotonobetaine/carnitine-CoA ligase [caiC]. 6 522 86.214 T 10-03-2017 IPR023456 Crotonobetaine/carnitine-CoA ligase CaiC GO:0009437|GO:0016878|GO:0051108|GO:0051109 RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 Gene3D G3DSA:3.40.50.980 189 347 1.5E-34 T 10-03-2017 RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 Gene3D G3DSA:3.40.50.980 14 188 2.2E-39 T 10-03-2017 RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 Gene3D G3DSA:2.30.38.10 348 422 8.4E-23 T 10-03-2017 RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 SUPERFAMILY SSF56801 14 522 3.66E-135 T 10-03-2017 RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 Gene3D G3DSA:3.30.300.30 428 522 7.8E-27 T 10-03-2017 RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 515 1.8E-15 T 10-03-2017 IPR025110 AMP-binding enzyme C-terminal domain RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS11680 e19099497206fd9a51956d20ee323f7a 522 Pfam PF00501 AMP-binding enzyme 22 431 7.4E-90 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 SUPERFAMILY SSF52540 7 642 1.72E-182 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Pfam PF13361 UvrD-like helicase C-terminal domain 277 616 1.2E-75 T 10-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Gene3D G3DSA:1.10.486.10 388 541 1.5E-52 T 10-03-2017 RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Gene3D G3DSA:3.40.50.300 191 285 1.5E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Gene3D G3DSA:3.40.50.300 5 110 1.5E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 271 6.8E-76 T 10-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Gene3D G3DSA:3.40.50.300 552 642 5.7E-73 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Gene3D G3DSA:3.40.50.300 286 387 5.7E-73 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 Gene3D G3DSA:1.10.10.160 114 190 1.0E-26 T 10-03-2017 IPR013986 DExx box DNA helicase domain RG49_RS15125 5564a064c33292c4eecd8a4ca796a715 720 TIGRFAM TIGR01075 uvrD: DNA helicase II 6 718 0.0 T 10-03-2017 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 SUPERFAMILY SSF50129 1 144 7.55E-47 T 10-03-2017 IPR011032 GroES-like RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 85 1.8E-4 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 Gene3D G3DSA:3.40.50.720 125 289 1.2E-80 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 Gene3D G3DSA:3.90.180.10 1 85 1.1E-6 T 10-03-2017 IPR011032 GroES-like RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 SMART SM00829 12 321 1.9E-4 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 Pfam PF00107 Zinc-binding dehydrogenase 158 282 5.5E-18 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 SUPERFAMILY SSF51735 116 284 9.36E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18345 62169f87c02bc4c162ea1adb1fec4587 324 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 2 323 6.0E-144 T 10-03-2017 IPR014188 Acrylyl-CoA reductase AcuI RG49_RS07245 4b77aa7d76c7b1946ca0d8ca6aa05562 338 Gene3D G3DSA:3.90.25.10 264 337 1.7E-50 T 10-03-2017 RG49_RS07245 4b77aa7d76c7b1946ca0d8ca6aa05562 338 Gene3D G3DSA:3.90.25.10 180 232 1.7E-50 T 10-03-2017 RG49_RS07245 4b77aa7d76c7b1946ca0d8ca6aa05562 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 335 7.0E-151 T 10-03-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 RG49_RS07245 4b77aa7d76c7b1946ca0d8ca6aa05562 338 SUPERFAMILY SSF51735 1 336 1.18E-101 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS07245 4b77aa7d76c7b1946ca0d8ca6aa05562 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 325 4.3E-66 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS07245 4b77aa7d76c7b1946ca0d8ca6aa05562 338 Gene3D G3DSA:3.40.50.720 1 179 2.7E-54 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17485 34ed057ca1d77c0cf97943aea6b8b747 694 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 100 685 2.0E-304 T 10-03-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 RG49_RS17485 34ed057ca1d77c0cf97943aea6b8b747 694 Pfam PF02446 4-alpha-glucanotransferase 148 664 7.1E-131 T 10-03-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 RG49_RS17485 34ed057ca1d77c0cf97943aea6b8b747 694 Gene3D G3DSA:3.20.20.80 612 686 4.5E-164 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS17485 34ed057ca1d77c0cf97943aea6b8b747 694 Gene3D G3DSA:3.20.20.80 140 573 4.5E-164 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS17485 34ed057ca1d77c0cf97943aea6b8b747 694 SUPERFAMILY SSF51445 142 570 7.37E-147 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS17485 34ed057ca1d77c0cf97943aea6b8b747 694 SUPERFAMILY SSF51445 608 681 7.37E-147 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS12820 1d7d71d4122550d069634eb58665ca78 286 Pfam PF05368 NmrA-like family 2 220 1.0E-24 T 10-03-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 RG49_RS12820 1d7d71d4122550d069634eb58665ca78 286 SUPERFAMILY SSF51735 2 252 8.98E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12820 1d7d71d4122550d069634eb58665ca78 286 Gene3D G3DSA:3.40.50.720 2 218 2.0E-42 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18695 da252a2c9269b079bc15906d45923c9b 419 SUPERFAMILY SSF55205 1 418 4.25E-147 T 10-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 RG49_RS18695 da252a2c9269b079bc15906d45923c9b 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 406 5.4E-131 T 10-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 RG49_RS18695 da252a2c9269b079bc15906d45923c9b 419 Gene3D G3DSA:3.65.10.10 220 416 3.8E-64 T 10-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 RG49_RS18695 da252a2c9269b079bc15906d45923c9b 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.1E-184 T 10-03-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS18695 da252a2c9269b079bc15906d45923c9b 419 Gene3D G3DSA:3.65.10.10 21 219 8.1E-68 T 10-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 RG49_RS18695 da252a2c9269b079bc15906d45923c9b 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 46.803 T 10-03-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 Pfam PF16582 Middle domain of thiamine pyrophosphate 184 388 1.8E-87 T 10-03-2017 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 Gene3D G3DSA:3.40.50.970 344 547 1.8E-32 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 SUPERFAMILY SSF52518 7 175 9.64E-32 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 141 6.9E-27 T 10-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 10 430 4.1E-139 T 10-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 Gene3D G3DSA:3.40.50.970 7 175 3.9E-44 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 4 553 32.786 T 10-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 415 535 1.6E-9 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 SUPERFAMILY SSF52518 367 552 4.42E-35 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23770 c9620a734dc63f2ffb4a0542c6ba0fb6 556 PIRSF PIRSF004983 1 556 4.8E-187 T 10-03-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 RG49_RS11345 a298a24b75c6cca43bd5aa7079e218e8 206 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 192 27.855 T 10-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 RG49_RS11345 a298a24b75c6cca43bd5aa7079e218e8 206 Gene3D G3DSA:3.40.50.300 2 199 1.7E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11345 a298a24b75c6cca43bd5aa7079e218e8 206 Pfam PF01121 Dephospho-CoA kinase 3 177 1.4E-77 T 10-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 RG49_RS11345 a298a24b75c6cca43bd5aa7079e218e8 206 SUPERFAMILY SSF52540 1 190 3.79E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11345 a298a24b75c6cca43bd5aa7079e218e8 206 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 1.5E-72 T 10-03-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 RG49_RS07500 f168dd59c7aea200d743cb5bbab9c6d4 818 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 297 307 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS07500 f168dd59c7aea200d743cb5bbab9c6d4 818 Pfam PF13953 PapC C-terminal domain 746 802 5.2E-11 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS07500 f168dd59c7aea200d743cb5bbab9c6d4 818 Pfam PF13954 PapC N-terminal domain 26 165 4.1E-33 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS07500 f168dd59c7aea200d743cb5bbab9c6d4 818 Pfam PF00577 Outer membrane usher protein 183 733 5.8E-188 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS07500 f168dd59c7aea200d743cb5bbab9c6d4 818 SUPERFAMILY SSF141729 24 141 5.36E-26 T 10-03-2017 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 334 6.8E-8 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 299 6.8E-8 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 356 2.0E-17 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 SUPERFAMILY SSF47384 126 199 2.55E-11 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 SUPERFAMILY SSF55874 192 354 2.23E-27 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 SMART SM00387 249 357 2.7E-23 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 Gene3D G3DSA:3.30.565.10 220 356 2.5E-28 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 SMART SM00304 89 141 5.9E-4 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 Gene3D G3DSA:1.10.287.130 134 198 4.7E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 Pfam PF00512 His Kinase A (phospho-acceptor) domain 144 200 5.4E-9 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 Pfam PF00672 HAMP domain 70 136 3.7E-7 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS13395 a79228ff04d66645288f6d0b0e985501 363 SMART SM00388 142 202 3.0E-9 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Gene3D G3DSA:1.20.50.20 368 426 2.0E-28 T 10-03-2017 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Pfam PF01807 CHC2 zinc finger 7 100 5.3E-41 T 10-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 PIRSF PIRSF002811 2 580 2.0E-146 T 10-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 251 1.1E-43 T 10-03-2017 IPR013264 DNA primase, catalytic core, N-terminal RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Hamap MF_00974 DNA primase [dnaG]. 4 576 30.615 T 10-03-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Gene3D G3DSA:3.90.980.10 116 240 2.6E-47 T 10-03-2017 IPR013264 DNA primase, catalytic core, N-terminal RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Pfam PF08278 DNA primase DnaG DnaB-binding 451 574 2.7E-33 T 10-03-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Pfam PF10410 DnaB-helicase binding domain of primase 369 424 8.3E-13 T 10-03-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 SUPERFAMILY SSF56731 115 428 2.62E-116 T 10-03-2017 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Gene3D G3DSA:3.90.580.10 1 100 1.5E-40 T 10-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 SMART SM00766 450 575 1.4E-48 T 10-03-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 SUPERFAMILY SSF117023 447 579 3.01E-43 T 10-03-2017 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Gene3D G3DSA:3.40.1360.10 241 366 1.6E-48 T 10-03-2017 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 SMART SM00493 259 330 2.3E-21 T 10-03-2017 IPR006171 Toprim domain RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 5.5E-152 T 10-03-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Gene3D G3DSA:1.10.860.10 437 580 4.5E-55 T 10-03-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 SUPERFAMILY SSF57783 4 100 8.67E-36 T 10-03-2017 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 SMART SM00400 36 90 7.6E-38 T 10-03-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 RG49_RS19400 0c2cc8fea54eb6aad442a02cf3b6c64b 581 Pfam PF13155 Toprim-like 263 348 4.0E-15 T 10-03-2017 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 SUPERFAMILY SSF50249 16 101 1.82E-17 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 Gene3D G3DSA:3.30.930.10 109 462 2.4E-111 T 10-03-2017 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 Gene3D G3DSA:2.40.50.140 16 103 2.0E-16 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 466 46.355 T 10-03-2017 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 SUPERFAMILY SSF55681 98 464 1.06E-95 T 10-03-2017 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 3.8E-14 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 3.8E-14 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 3.8E-14 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 3.8E-14 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 460 3.7E-82 T 10-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 466 1.6E-212 T 10-03-2017 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 RG49_RS06075 2d207fb81116741552eeb7ee964cf312 466 Pfam PF01336 OB-fold nucleic acid binding domain 20 99 1.8E-12 T 10-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 RG49_RS21760 3ab1e503e3e953ea6b91720eb832faaf 52 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 7 22 - T 10-03-2017 IPR000612 Proteolipid membrane potential modulator GO:0016021 RG49_RS21760 3ab1e503e3e953ea6b91720eb832faaf 52 Pfam PF01679 Proteolipid membrane potential modulator 3 48 1.6E-18 T 10-03-2017 IPR000612 Proteolipid membrane potential modulator GO:0016021 RG49_RS12825 7a88297fe9363905aec85cd719b2a14b 321 Pfam PF00892 EamA-like transporter family 3 125 1.2E-15 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS12825 7a88297fe9363905aec85cd719b2a14b 321 SUPERFAMILY SSF103481 43 136 3.27E-9 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 SUPERFAMILY SSF55124 502 627 5.72E-31 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS17765 629424812b09b0544699744b7968ce01 847 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 292 3.4E-51 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17765 629424812b09b0544699744b7968ce01 847 SUPERFAMILY SSF51905 2 189 3.14E-39 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17765 629424812b09b0544699744b7968ce01 847 Pfam PF04324 BFD-like [2Fe-2S] binding domain 424 471 8.3E-15 T 10-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 3.8E-11 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 3.8E-11 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 3.8E-11 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 105 114 3.8E-11 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 560 622 1.0E-11 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS17765 629424812b09b0544699744b7968ce01 847 Gene3D G3DSA:3.50.50.60 106 309 3.9E-50 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 4.1E-14 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 4.1E-14 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 4.1E-14 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 4.1E-14 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 633 757 7.1E-15 T 10-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00397 Sirohaem Fe-binding site signature 679 697 1.3E-5 T 10-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PRINTS PR00397 Sirohaem Fe-binding site signature 636 654 1.3E-5 T 10-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS17765 629424812b09b0544699744b7968ce01 847 SUPERFAMILY SSF51905 144 310 5.7E-28 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17765 629424812b09b0544699744b7968ce01 847 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 801 0.0 T 10-03-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 RG49_RS17765 629424812b09b0544699744b7968ce01 847 SUPERFAMILY SSF56014 633 808 1.83E-46 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 PIRSF PIRSF037149 1 835 0.0 T 10-03-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 RG49_RS17765 629424812b09b0544699744b7968ce01 847 Gene3D G3DSA:3.30.413.10 634 768 1.7E-30 T 10-03-2017 RG49_RS17765 629424812b09b0544699744b7968ce01 847 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 679 695 - T 10-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS17765 629424812b09b0544699744b7968ce01 847 Gene3D G3DSA:3.50.50.60 2 105 1.3E-23 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 Gene3D G3DSA:3.40.190.10 266 291 1.2E-5 T 10-03-2017 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 Gene3D G3DSA:3.40.190.10 117 162 1.2E-5 T 10-03-2017 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.3E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.3E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.3E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 SUPERFAMILY SSF53850 91 292 1.56E-31 T 10-03-2017 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 SUPERFAMILY SSF46785 3 82 4.73E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 Gene3D G3DSA:1.10.10.10 3 78 1.1E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 Pfam PF03466 LysR substrate binding domain 89 290 9.0E-28 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.8E-21 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03670 3dd9a27fed2df197681ed65784549eb9 293 Gene3D G3DSA:3.40.190.10 163 257 8.1E-17 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 Gene3D G3DSA:3.40.50.880 1 186 2.2E-69 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 6.1E-6 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 6.1E-6 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 2.2E-99 T 10-03-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 SUPERFAMILY SSF52317 1 186 2.72E-57 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 Pfam PF00117 Glutamine amidotransferase class-I 3 186 5.4E-57 T 10-03-2017 IPR017926 Glutamine amidotransferase RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 6.9E-14 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 6.9E-14 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 6.9E-14 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.8E-37 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.8E-37 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.8E-37 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.8E-37 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.8E-37 T 10-03-2017 RG49_RS17790 561642d7f46dcb3b4b9a787724e0baaa 187 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.8E-37 T 10-03-2017 RG49_RS18920 739246344f7764a504873bdd934f0831 678 Gene3D G3DSA:3.40.50.2300 525 600 2.1E-55 T 10-03-2017 RG49_RS18920 739246344f7764a504873bdd934f0831 678 Gene3D G3DSA:3.40.50.2300 425 485 2.1E-55 T 10-03-2017 RG49_RS18920 739246344f7764a504873bdd934f0831 678 Gene3D G3DSA:3.40.50.2300 354 424 2.8E-75 T 10-03-2017 RG49_RS18920 739246344f7764a504873bdd934f0831 678 Gene3D G3DSA:3.40.50.2300 601 665 2.8E-75 T 10-03-2017 RG49_RS18920 739246344f7764a504873bdd934f0831 678 Gene3D G3DSA:3.40.50.2300 256 287 2.8E-75 T 10-03-2017 RG49_RS18920 739246344f7764a504873bdd934f0831 678 SUPERFAMILY SSF53822 258 287 3.41E-72 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS18920 739246344f7764a504873bdd934f0831 678 SUPERFAMILY SSF53822 523 677 3.41E-72 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS18920 739246344f7764a504873bdd934f0831 678 SUPERFAMILY SSF53822 352 484 3.41E-72 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS18920 739246344f7764a504873bdd934f0831 678 Hamap MF_01890 Penicillin-binding protein activator LpoA [lpoA]. 1 672 36.49 T 10-03-2017 IPR007443 Penicillin-binding protein activator LpoA RG49_RS18920 739246344f7764a504873bdd934f0831 678 SUPERFAMILY SSF48435 50 150 1.24E-5 T 10-03-2017 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 RG49_RS18920 739246344f7764a504873bdd934f0831 678 Pfam PF04348 LppC putative lipoprotein 346 672 2.1E-86 T 10-03-2017 IPR007443 Penicillin-binding protein activator LpoA RG49_RS18920 739246344f7764a504873bdd934f0831 678 Gene3D G3DSA:1.25.40.10 69 141 1.6E-4 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS06045 1bfb9032a7a4df03d61ec4efa5cb0546 319 SMART SM00062 28 249 3.8E-38 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS06045 1bfb9032a7a4df03d61ec4efa5cb0546 319 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 29 309 1.7E-86 T 10-03-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 RG49_RS06045 1bfb9032a7a4df03d61ec4efa5cb0546 319 Pfam PF09084 NMT1/THI5 like 67 183 1.2E-12 T 10-03-2017 IPR015168 SsuA/THI5-like RG49_RS06045 1bfb9032a7a4df03d61ec4efa5cb0546 319 Gene3D G3DSA:3.40.190.10 110 227 1.2E-31 T 10-03-2017 RG49_RS06045 1bfb9032a7a4df03d61ec4efa5cb0546 319 Gene3D G3DSA:3.40.190.10 30 80 9.7E-4 T 10-03-2017 RG49_RS06045 1bfb9032a7a4df03d61ec4efa5cb0546 319 SUPERFAMILY SSF53850 26 258 4.4E-51 T 10-03-2017 RG49_RS03635 d16dd31bfca69913822434504957fb74 142 Gene3D G3DSA:3.30.1150.10 46 142 4.2E-36 T 10-03-2017 RG49_RS03635 d16dd31bfca69913822434504957fb74 142 TIGRFAM TIGR02794 tolA_full: protein TolA 46 142 1.1E-21 T 10-03-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 RG49_RS03635 d16dd31bfca69913822434504957fb74 142 SUPERFAMILY SSF74653 57 142 1.73E-17 T 10-03-2017 RG49_RS03635 d16dd31bfca69913822434504957fb74 142 Pfam PF06519 TolA C-terminal 49 140 3.8E-23 T 10-03-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 Gene3D G3DSA:3.40.50.300 192 464 3.7E-104 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 Gene3D G3DSA:1.10.860.10 27 129 5.8E-42 T 10-03-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 SUPERFAMILY SSF48024 25 136 1.23E-39 T 10-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 SUPERFAMILY SSF52540 204 275 1.97E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 SUPERFAMILY SSF52540 302 456 1.97E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 27 464 4.1E-175 T 10-03-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 Pfam PF03796 DnaB-like helicase C terminal domain 206 462 1.9E-113 T 10-03-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 SMART SM00382 223 429 5.3E-4 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS13770 6f953429824e1de805af19f8ff1e525e 471 Pfam PF00772 DnaB-like helicase N terminal domain 27 128 3.0E-37 T 10-03-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 SMART SM01005 234 358 1.2E-62 T 10-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 TIGRFAM TIGR00492 alr: alanine racemase 3 359 4.4E-151 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 10-03-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 Hamap MF_01201 Alanine racemase. 1 358 34.665 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 267 282 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 288 305 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 155 166 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 192 219 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 60 78 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 340 353 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 26 42 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 250 265 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 PRINTS PR00992 Alanine racemase signature 120 132 7.8E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 SUPERFAMILY SSF51419 8 235 3.93E-68 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 Pfam PF01168 Alanine racemase, N-terminal domain 8 219 4.7E-70 T 10-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 SUPERFAMILY SSF50621 228 358 4.19E-44 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 Gene3D G3DSA:3.20.20.10 11 212 5.5E-75 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 Gene3D G3DSA:2.40.37.10 213 359 6.6E-55 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS13765 ea173a5bec113125bcaa7b701205052b 359 Pfam PF00842 Alanine racemase, C-terminal domain 234 357 2.6E-37 T 10-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS14105 9fae77ec817b5fcd7c21904222a9dd9b 257 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 93 124 4.9E-10 T 10-03-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 RG49_RS14105 9fae77ec817b5fcd7c21904222a9dd9b 257 SUPERFAMILY SSF55811 3 96 1.32E-31 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS14105 9fae77ec817b5fcd7c21904222a9dd9b 257 Gene3D G3DSA:3.90.79.10 93 246 2.4E-42 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS14105 9fae77ec817b5fcd7c21904222a9dd9b 257 ProSitePatterns PS00893 Nudix box signature. 159 180 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS14105 9fae77ec817b5fcd7c21904222a9dd9b 257 Hamap MF_00297 NADH pyrophosphatase [nudC]. 1 257 47.968 T 10-03-2017 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 RG49_RS14105 9fae77ec817b5fcd7c21904222a9dd9b 257 Pfam PF00293 NUDIX domain 132 234 1.6E-17 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS14105 9fae77ec817b5fcd7c21904222a9dd9b 257 SUPERFAMILY SSF55811 79 241 1.62E-40 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS08820 21d69c0d29a7a2a08d8e020eb8fefca8 516 SUPERFAMILY SSF141868 273 514 6.41E-75 T 10-03-2017 IPR001633 EAL domain RG49_RS08820 21d69c0d29a7a2a08d8e020eb8fefca8 516 SMART SM00052 267 507 7.4E-113 T 10-03-2017 IPR001633 EAL domain RG49_RS08820 21d69c0d29a7a2a08d8e020eb8fefca8 516 Pfam PF12792 CSS motif domain associated with EAL 39 242 1.5E-44 T 10-03-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain RG49_RS08820 21d69c0d29a7a2a08d8e020eb8fefca8 516 Gene3D G3DSA:3.20.20.450 273 514 2.2E-80 T 10-03-2017 IPR001633 EAL domain RG49_RS08820 21d69c0d29a7a2a08d8e020eb8fefca8 516 Pfam PF00563 EAL domain 274 501 9.1E-65 T 10-03-2017 IPR001633 EAL domain RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Gene3D G3DSA:3.40.120.10 318 441 1.0E-35 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 10-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 482 538 3.7E-8 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Gene3D G3DSA:3.40.120.10 30 225 7.8E-61 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 SUPERFAMILY SSF53738 305 446 2.24E-32 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 SUPERFAMILY SSF53738 209 317 6.59E-8 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Gene3D G3DSA:3.40.120.10 226 316 9.4E-45 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 179 9.2E-36 T 10-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 SUPERFAMILY SSF53738 26 235 3.53E-49 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 544 0.0 T 10-03-2017 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 320 440 6.2E-31 T 10-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 2.3E-19 T 10-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 Gene3D G3DSA:3.30.310.50 466 545 9.9E-31 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS07660 5de89c9e69d5d46ace30928078064499 546 SUPERFAMILY SSF55957 433 544 5.93E-20 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 Gene3D G3DSA:3.40.50.150 86 274 3.8E-71 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 Gene3D G3DSA:1.10.8.10 1 84 5.7E-31 T 10-03-2017 RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 1 277 2.0E-107 T 10-03-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 271 6.4E-90 T 10-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 SUPERFAMILY SSF53335 3 275 1.2E-59 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 275 47.116 T 10-03-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 RG49_RS04570 25069df14c958fde0c20e5dc3612aed3 277 Pfam PF13847 Methyltransferase domain 108 243 9.2E-21 T 10-03-2017 IPR025714 Methyltransferase domain RG49_RS04630 bd87689fc5983f70c15e2bd9d7e54bfb 91 Pfam PF12759 InsA C-terminal domain 43 88 4.6E-31 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS04630 bd87689fc5983f70c15e2bd9d7e54bfb 91 Pfam PF03811 InsA N-terminal domain 2 36 2.3E-20 T 10-03-2017 IPR003220 InsA N-terminal domain GO:0006313 RG49_RS04630 bd87689fc5983f70c15e2bd9d7e54bfb 91 Gene3D G3DSA:1.10.10.60 53 86 0.001 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08830 bd87689fc5983f70c15e2bd9d7e54bfb 91 Pfam PF12759 InsA C-terminal domain 43 88 4.6E-31 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS08830 bd87689fc5983f70c15e2bd9d7e54bfb 91 Pfam PF03811 InsA N-terminal domain 2 36 2.3E-20 T 10-03-2017 IPR003220 InsA N-terminal domain GO:0006313 RG49_RS08830 bd87689fc5983f70c15e2bd9d7e54bfb 91 Gene3D G3DSA:1.10.10.60 53 86 0.001 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS07485 bd87689fc5983f70c15e2bd9d7e54bfb 91 Pfam PF12759 InsA C-terminal domain 43 88 4.6E-31 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS07485 bd87689fc5983f70c15e2bd9d7e54bfb 91 Pfam PF03811 InsA N-terminal domain 2 36 2.3E-20 T 10-03-2017 IPR003220 InsA N-terminal domain GO:0006313 RG49_RS07485 bd87689fc5983f70c15e2bd9d7e54bfb 91 Gene3D G3DSA:1.10.10.60 53 86 0.001 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08100 5c09e1fccbdf2cf009b12ce39f427bbf 248 SUPERFAMILY SSF52833 82 242 8.37E-39 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08100 5c09e1fccbdf2cf009b12ce39f427bbf 248 Gene3D G3DSA:3.40.30.10 105 246 6.5E-36 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08100 5c09e1fccbdf2cf009b12ce39f427bbf 248 SUPERFAMILY SSF54423 19 78 7.98E-23 T 10-03-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal RG49_RS08100 5c09e1fccbdf2cf009b12ce39f427bbf 248 Pfam PF13098 Thioredoxin-like domain 115 241 6.2E-16 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS16695 6b5dab8665664d9033bada6077f9f47a 173 SUPERFAMILY SSF48295 2 60 1.88E-11 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS16695 6b5dab8665664d9033bada6077f9f47a 173 SUPERFAMILY SSF48295 63 121 1.62E-10 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS16695 6b5dab8665664d9033bada6077f9f47a 173 Gene3D G3DSA:1.10.10.60 9 54 1.5E-4 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16695 6b5dab8665664d9033bada6077f9f47a 173 Gene3D G3DSA:1.10.10.60 65 166 1.8E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16695 6b5dab8665664d9033bada6077f9f47a 173 Pfam PF13518 Helix-turn-helix domain 68 114 8.4E-10 T 10-03-2017 RG49_RS16695 6b5dab8665664d9033bada6077f9f47a 173 Pfam PF13518 Helix-turn-helix domain 10 60 4.9E-9 T 10-03-2017 RG49_RS11790 6b5dab8665664d9033bada6077f9f47a 173 SUPERFAMILY SSF48295 2 60 1.88E-11 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS11790 6b5dab8665664d9033bada6077f9f47a 173 SUPERFAMILY SSF48295 63 121 1.62E-10 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS11790 6b5dab8665664d9033bada6077f9f47a 173 Gene3D G3DSA:1.10.10.60 9 54 1.5E-4 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11790 6b5dab8665664d9033bada6077f9f47a 173 Gene3D G3DSA:1.10.10.60 65 166 1.8E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11790 6b5dab8665664d9033bada6077f9f47a 173 Pfam PF13518 Helix-turn-helix domain 68 114 8.4E-10 T 10-03-2017 RG49_RS11790 6b5dab8665664d9033bada6077f9f47a 173 Pfam PF13518 Helix-turn-helix domain 10 60 4.9E-9 T 10-03-2017 RG49_RS08255 6b5dab8665664d9033bada6077f9f47a 173 SUPERFAMILY SSF48295 2 60 1.88E-11 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS08255 6b5dab8665664d9033bada6077f9f47a 173 SUPERFAMILY SSF48295 63 121 1.62E-10 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS08255 6b5dab8665664d9033bada6077f9f47a 173 Gene3D G3DSA:1.10.10.60 9 54 1.5E-4 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08255 6b5dab8665664d9033bada6077f9f47a 173 Gene3D G3DSA:1.10.10.60 65 166 1.8E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08255 6b5dab8665664d9033bada6077f9f47a 173 Pfam PF13518 Helix-turn-helix domain 68 114 8.4E-10 T 10-03-2017 RG49_RS08255 6b5dab8665664d9033bada6077f9f47a 173 Pfam PF13518 Helix-turn-helix domain 10 60 4.9E-9 T 10-03-2017 RG49_RS11060 fcca46129e2a583d786e10ac7feb6281 660 SUPERFAMILY SSF81345 6 325 3.4E-59 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS11060 fcca46129e2a583d786e10ac7feb6281 660 Gene3D G3DSA:1.10.3470.10 7 327 6.2E-74 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS11060 fcca46129e2a583d786e10ac7feb6281 660 Pfam PF01032 FecCD transport family 16 323 1.9E-63 T 10-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 RG49_RS11060 fcca46129e2a583d786e10ac7feb6281 660 Pfam PF01032 FecCD transport family 359 657 4.9E-75 T 10-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 RG49_RS11060 fcca46129e2a583d786e10ac7feb6281 660 Gene3D G3DSA:1.10.3470.10 342 659 5.8E-83 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS11060 fcca46129e2a583d786e10ac7feb6281 660 SUPERFAMILY SSF81345 345 657 6.02E-73 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS00240 bf85ab08207a8a998620d5153899d269 77 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 10 34 - T 10-03-2017 IPR001455 TusA-like domain RG49_RS00240 bf85ab08207a8a998620d5153899d269 77 Pfam PF01206 Sulfurtransferase TusA 9 77 1.2E-19 T 10-03-2017 IPR001455 TusA-like domain RG49_RS00240 bf85ab08207a8a998620d5153899d269 77 SUPERFAMILY SSF64307 3 77 5.1E-24 T 10-03-2017 IPR001455 TusA-like domain RG49_RS00240 bf85ab08207a8a998620d5153899d269 77 Gene3D G3DSA:3.30.110.40 6 77 2.5E-33 T 10-03-2017 IPR001455 TusA-like domain RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 Gene3D G3DSA:1.10.10.10 16 100 1.2E-33 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 81 4.5E-18 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 SUPERFAMILY SSF46785 19 98 1.5E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 Gene3D G3DSA:3.40.190.10 105 187 3.3E-21 T 10-03-2017 RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 Gene3D G3DSA:3.40.190.10 287 314 3.3E-21 T 10-03-2017 RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 60 2.1E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.1E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 60 71 2.1E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 Pfam PF03466 LysR substrate binding domain 137 309 3.0E-16 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 SUPERFAMILY SSF53850 105 311 1.32E-39 T 10-03-2017 RG49_RS11480 e973584cb8c7ca4928cacfb5714d2ae3 314 Gene3D G3DSA:3.40.190.10 188 281 7.6E-18 T 10-03-2017 RG49_RS16080 23d77e07fc3af311ee66f53986c4cd95 433 Gene3D G3DSA:1.20.1250.20 234 431 3.6E-23 T 10-03-2017 RG49_RS16080 23d77e07fc3af311ee66f53986c4cd95 433 Gene3D G3DSA:1.20.1250.20 19 212 3.7E-46 T 10-03-2017 RG49_RS16080 23d77e07fc3af311ee66f53986c4cd95 433 Pfam PF07690 Major Facilitator Superfamily 30 390 3.7E-54 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS16080 23d77e07fc3af311ee66f53986c4cd95 433 SUPERFAMILY SSF103473 15 431 1.7E-79 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 Pfam PF16330 MukB hinge domain 645 810 5.3E-74 T 10-03-2017 IPR032520 MukB, hinge domain RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 SUPERFAMILY SSF52540 22 224 4.04E-23 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 Pfam PF04310 MukB N-terminal 2 227 6.1E-125 T 10-03-2017 IPR007406 MukB, N-terminal domain GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 PIRSF PIRSF005246 1 1486 0.0 T 10-03-2017 IPR012090 Chromosome partition protein MukB GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 Gene3D G3DSA:3.40.1140.10 1 226 5.4E-51 T 10-03-2017 RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 SUPERFAMILY SSF52540 1253 1433 1.49E-6 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 SUPERFAMILY SSF52540 21 55 1.49E-6 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1336 1424 7.4E-15 T 10-03-2017 RG49_RS06115 8d8f0a0015a271dbc9e058f8d8df327c 1486 Hamap MF_01800 Chromosome partition protein MukB [mukB]. 1 1471 11.403 T 10-03-2017 IPR012090 Chromosome partition protein MukB GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 RG49_RS24215 f4f08edd306f448c81f9dd6169c602a6 94 SUPERFAMILY SSF50715 1 93 7.32E-32 T 10-03-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS24215 f4f08edd306f448c81f9dd6169c602a6 94 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 2 94 28.446 T 10-03-2017 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 RG49_RS24215 f4f08edd306f448c81f9dd6169c602a6 94 Gene3D G3DSA:2.40.240.10 1 93 4.0E-36 T 10-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS24215 f4f08edd306f448c81f9dd6169c602a6 94 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 93 9.0E-46 T 10-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 RG49_RS24215 f4f08edd306f448c81f9dd6169c602a6 94 Pfam PF01386 Ribosomal L25p family 4 91 2.3E-25 T 10-03-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 SUPERFAMILY SSF55804 2 140 1.57E-39 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 326 341 - T 10-03-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 286 368 1.6E-21 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 Pfam PF00381 PTS HPr component phosphorylation site 287 368 8.1E-24 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 297 304 - T 10-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 Gene3D G3DSA:3.30.1340.10 287 374 3.4E-31 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 SUPERFAMILY SSF55804 150 276 2.79E-12 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 SUPERFAMILY SSF55594 287 375 5.5E-24 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 Gene3D G3DSA:3.40.930.10 150 278 2.0E-11 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 PRINTS PR00107 Phosphocarrier protein signature 340 357 2.1E-18 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 PRINTS PR00107 Phosphocarrier protein signature 297 313 2.1E-18 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 PRINTS PR00107 Phosphocarrier protein signature 325 340 2.1E-18 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 Gene3D G3DSA:3.40.930.10 5 141 9.1E-41 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 139 1.4E-29 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS24310 76d373ba0068fd85094e2559dd07a94a 376 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS06420 b3fc6624eaef3f7485c560cb53730841 349 SUPERFAMILY SSF51735 12 282 9.8E-61 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06420 b3fc6624eaef3f7485c560cb53730841 349 SUPERFAMILY SSF51735 310 347 9.8E-61 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06420 b3fc6624eaef3f7485c560cb53730841 349 Gene3D G3DSA:3.90.25.10 317 344 1.2E-5 T 10-03-2017 RG49_RS06420 b3fc6624eaef3f7485c560cb53730841 349 Gene3D G3DSA:3.40.50.720 12 260 6.8E-42 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06420 b3fc6624eaef3f7485c560cb53730841 349 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 246 1.2E-26 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS23840 bd427212e7dc629187a9b83cdc1b70a2 141 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS23840 bd427212e7dc629187a9b83cdc1b70a2 141 PRINTS PR00502 NUDIX hydrolase family signature 33 47 3.2E-6 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS23840 bd427212e7dc629187a9b83cdc1b70a2 141 PRINTS PR00502 NUDIX hydrolase family signature 47 62 3.2E-6 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS23840 bd427212e7dc629187a9b83cdc1b70a2 141 SUPERFAMILY SSF55811 2 126 6.5E-26 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS23840 bd427212e7dc629187a9b83cdc1b70a2 141 Pfam PF00293 NUDIX domain 2 135 4.4E-21 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS23840 bd427212e7dc629187a9b83cdc1b70a2 141 Hamap MF_01846 Nucleoside triphosphatase NudI [nudI]. 1 141 51.948 T 10-03-2017 IPR023781 Nucleoside triphosphatase NudI GO:0016818 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.23+3.6.1.19+3.6.1.12|KEGG: 00983+3.6.1.19|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206 RG49_RS23840 bd427212e7dc629187a9b83cdc1b70a2 141 Gene3D G3DSA:3.90.79.10 4 125 2.0E-24 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS11510 7bd22be610655f28c1c1c51319de7046 392 Pfam PF07690 Major Facilitator Superfamily 19 302 1.5E-24 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS11510 7bd22be610655f28c1c1c51319de7046 392 SUPERFAMILY SSF103473 15 388 1.96E-43 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS11510 7bd22be610655f28c1c1c51319de7046 392 TIGRFAM TIGR00899 2A0120: sugar efflux transporter 17 391 3.6E-181 T 10-03-2017 IPR004750 Sugar efflux GO:0008643|GO:0015542|GO:0016021 RG49_RS11510 7bd22be610655f28c1c1c51319de7046 392 Gene3D G3DSA:1.20.1250.20 216 388 5.6E-19 T 10-03-2017 RG49_RS11510 7bd22be610655f28c1c1c51319de7046 392 Gene3D G3DSA:1.20.1250.20 16 199 1.6E-18 T 10-03-2017 RG49_RS17015 f90d9768af1e4cbc5b1d3b6db676293c 188 Pfam PF03843 Outer membrane lipoprotein Slp family 16 165 6.6E-44 T 10-03-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 RG49_RS17015 f90d9768af1e4cbc5b1d3b6db676293c 188 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 2 183 6.0E-91 T 10-03-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 RG49_RS17015 f90d9768af1e4cbc5b1d3b6db676293c 188 PIRSF PIRSF004982 1 184 3.5E-56 T 10-03-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 236 249 1.5E-33 T 10-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 282 298 1.5E-33 T 10-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 209 220 1.5E-33 T 10-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 76 87 1.5E-33 T 10-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 306 319 1.5E-33 T 10-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 SUPERFAMILY SSF101353 256 465 6.28E-62 T 10-03-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 SMART SM00863 653 696 7.6E-22 T 10-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 696 8.6E-18 T 10-03-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 SUPERFAMILY SSF55681 4 255 1.04E-108 T 10-03-2017 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 Gene3D G3DSA:3.30.930.10 4 251 2.6E-128 T 10-03-2017 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 SUPERFAMILY SSF55186 552 708 1.57E-52 T 10-03-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 7 854 0.0 T 10-03-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 SUPERFAMILY SSF50447 455 551 1.27E-21 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 Pfam PF02272 DHHA1 domain 800 868 4.0E-17 T 10-03-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 Pfam PF01411 tRNA synthetases class II (A) 7 556 1.1E-241 T 10-03-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 RG49_RS21605 7e88afdd0d0a0c72076b8ed02b3c7385 876 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 875 210.019 T 10-03-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 RG49_RS16075 aa3a1b96f02acb3e016a87e4b88bd6a7 793 Pfam PF01055 Glycosyl hydrolases family 31 238 681 1.4E-116 T 10-03-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 RG49_RS16075 aa3a1b96f02acb3e016a87e4b88bd6a7 793 SUPERFAMILY SSF51011 597 678 9.35E-20 T 10-03-2017 RG49_RS16075 aa3a1b96f02acb3e016a87e4b88bd6a7 793 Pfam PF17137 Domain of unknown function (DUF5110) 701 765 1.5E-6 T 10-03-2017 IPR033403 Domain of unknown function DUF5110 RG49_RS16075 aa3a1b96f02acb3e016a87e4b88bd6a7 793 SUPERFAMILY SSF51445 247 594 8.73E-71 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS16075 aa3a1b96f02acb3e016a87e4b88bd6a7 793 Pfam PF13802 Galactose mutarotase-like 146 213 3.3E-22 T 10-03-2017 IPR025887 Glycoside hydrolase family 31, N-terminal domain RG49_RS16075 aa3a1b96f02acb3e016a87e4b88bd6a7 793 SUPERFAMILY SSF74650 2 242 6.91E-48 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS13335 7d1a88b095b80496a6d16a9d46c36d98 446 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 6 376 1.5E-149 T 10-03-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 RG49_RS13335 7d1a88b095b80496a6d16a9d46c36d98 446 PIRSF PIRSF004539 1 444 4.6E-197 T 10-03-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 RG49_RS13335 7d1a88b095b80496a6d16a9d46c36d98 446 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 443 2.0E-203 T 10-03-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 709 735 1.3E-68 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 577 606 1.3E-68 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 245 260 1.3E-68 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 386 406 1.3E-68 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 535 555 1.3E-68 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 1.3E-68 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 1.3E-68 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 10-03-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 SUPERFAMILY SSF51621 6 883 0.0 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 883 1.4E-295 T 10-03-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 883 18.502 T 10-03-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 537 549 - T 10-03-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 RG49_RS14335 a75fa3e22c2a164e8d5632867b4e2dd8 883 Gene3D G3DSA:1.20.1440.90 273 388 1.3E-32 T 10-03-2017 RG49_RS22895 96c137a4ef700cb6ff449a08a17b2e19 467 PIRSF PIRSF036410 1 467 4.6E-214 T 10-03-2017 IPR012408 Acetaldehyde/propionaldehyde dehydrogenase, EutE/PduP-related RG49_RS22895 96c137a4ef700cb6ff449a08a17b2e19 467 Gene3D G3DSA:3.40.309.10 250 424 2.3E-25 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS22895 96c137a4ef700cb6ff449a08a17b2e19 467 SUPERFAMILY SSF53720 34 458 3.01E-62 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS22895 96c137a4ef700cb6ff449a08a17b2e19 467 Pfam PF00171 Aldehyde dehydrogenase family 34 422 1.8E-30 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS22895 96c137a4ef700cb6ff449a08a17b2e19 467 Gene3D G3DSA:3.40.605.10 35 249 3.4E-24 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS17300 5ae0816c961f60a72196781e72d7205e 255 Gene3D G3DSA:3.40.50.300 2 251 4.0E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17300 5ae0816c961f60a72196781e72d7205e 255 SUPERFAMILY SSF52540 4 253 6.48E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17300 5ae0816c961f60a72196781e72d7205e 255 Pfam PF00005 ABC transporter 21 181 3.0E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17300 5ae0816c961f60a72196781e72d7205e 255 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17300 5ae0816c961f60a72196781e72d7205e 255 SMART SM00382 30 230 6.6E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17300 5ae0816c961f60a72196781e72d7205e 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 253 2.1E-10 T 10-03-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 Gene3D G3DSA:1.10.287.80 19 60 5.2E-40 T 10-03-2017 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 Gene3D G3DSA:1.10.287.80 202 235 5.2E-40 T 10-03-2017 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 Gene3D G3DSA:3.40.1380.10 63 191 5.0E-44 T 10-03-2017 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 SUPERFAMILY SSF52943 2 287 5.1E-97 T 10-03-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 Gene3D G3DSA:1.10.287.80 236 282 4.6E-30 T 10-03-2017 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 1.9E-113 T 10-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 1.9E-37 T 10-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.9E-37 T 10-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 1.9E-37 T 10-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.9E-37 T 10-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 36.385 T 10-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 Pfam PF00231 ATP synthase 5 286 9.5E-92 T 10-03-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15545 d21bdcc2f9fc8b3e07ce5eaed473d7bb 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 10-03-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 9.4E-12 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 9.4E-12 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 9.4E-12 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 Gene3D G3DSA:1.10.1660.10 1 56 3.6E-28 T 10-03-2017 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 SUPERFAMILY SSF46955 2 121 2.53E-35 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 TIGRFAM TIGR02043 ZntR: Zn(II)-responsive transcriptional regulator 1 131 3.8E-62 T 10-03-2017 IPR011788 Zn(II)-responsive transcriptional regulator GO:0003677|GO:0006351|GO:0008270 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 Gene3D G3DSA:1.10.1660.10 57 136 3.7E-34 T 10-03-2017 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 Pfam PF13411 MerR HTH family regulatory protein 2 69 6.8E-21 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS18140 e97ebe0750cea743d147d9f5f771bfc2 141 SMART SM00422 2 71 2.1E-34 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS03050 b5799dae2c50efd7f74cb117ee504578 189 SMART SM00903 14 158 5.8E-15 T 10-03-2017 IPR002563 Flavin reductase like domain GO:0010181 RG49_RS03050 b5799dae2c50efd7f74cb117ee504578 189 Pfam PF01613 Flavin reductase like domain 19 151 7.5E-15 T 10-03-2017 IPR002563 Flavin reductase like domain GO:0010181 RG49_RS03050 b5799dae2c50efd7f74cb117ee504578 189 SUPERFAMILY SSF50475 8 186 2.11E-38 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS03050 b5799dae2c50efd7f74cb117ee504578 189 Gene3D G3DSA:2.30.110.10 6 187 9.1E-47 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 SUPERFAMILY SSF46785 4 61 1.32E-12 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 2.1E-21 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 Pfam PF00455 DeoR C terminal sensor domain 74 231 3.5E-52 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 SMART SM00420 6 58 3.9E-23 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 SUPERFAMILY SSF100950 73 234 3.89E-37 T 10-03-2017 RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 Gene3D G3DSA:1.10.10.10 1 60 5.9E-10 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 SMART SM01134 72 233 1.7E-72 T 10-03-2017 RG49_RS21550 d8d0322f11a1f10f81fdf876adf44f1d 257 Gene3D G3DSA:3.40.50.1360 76 215 3.5E-17 T 10-03-2017 RG49_RS12395 771c2b56cd6f1eb84f3386502be51344 394 SUPERFAMILY SSF51658 1 133 2.09E-79 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12395 771c2b56cd6f1eb84f3386502be51344 394 SUPERFAMILY SSF51658 163 383 2.09E-79 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12395 771c2b56cd6f1eb84f3386502be51344 394 PIRSF PIRSF016049 1 392 7.8E-184 T 10-03-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 RG49_RS12395 771c2b56cd6f1eb84f3386502be51344 394 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 394 6.3E-239 T 10-03-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 RG49_RS12395 771c2b56cd6f1eb84f3386502be51344 394 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 388 1.2E-167 T 10-03-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 RG49_RS12395 771c2b56cd6f1eb84f3386502be51344 394 Gene3D G3DSA:3.20.20.150 1 391 5.1E-156 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12395 771c2b56cd6f1eb84f3386502be51344 394 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 394 225.989 T 10-03-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 RG49_RS19835 666cce50e14b066c06042b39585c043a 237 SUPERFAMILY SSF52540 14 127 9.77E-10 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19835 666cce50e14b066c06042b39585c043a 237 Gene3D G3DSA:3.40.50.300 13 235 1.1E-12 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07350 9067a729989cc3fb5b5d1ded58b8d1e0 421 SUPERFAMILY SSF74653 334 421 8.24E-23 T 10-03-2017 RG49_RS07350 9067a729989cc3fb5b5d1ded58b8d1e0 421 Pfam PF06519 TolA C-terminal 326 419 3.9E-38 T 10-03-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 RG49_RS07350 9067a729989cc3fb5b5d1ded58b8d1e0 421 TIGRFAM TIGR02794 tolA_full: protein TolA 232 421 2.5E-45 T 10-03-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 RG49_RS07350 9067a729989cc3fb5b5d1ded58b8d1e0 421 TIGRFAM TIGR02794 tolA_full: protein TolA 12 245 6.9E-48 T 10-03-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 RG49_RS07350 9067a729989cc3fb5b5d1ded58b8d1e0 421 Gene3D G3DSA:3.30.1150.10 323 421 2.6E-45 T 10-03-2017 RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 SUPERFAMILY SSF54909 91 180 1.17E-20 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 SUPERFAMILY SSF46785 30 90 1.85E-15 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 Pfam PF01037 Lrp/AsnC ligand binding domain 97 171 1.1E-21 T 10-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 58 77 1.9E-10 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 47 1.9E-10 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 47 58 1.9E-10 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 ProSitePatterns PS00519 AsnC-type HTH domain signature. 49 75 - T 10-03-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 SMART SM00344 31 140 1.2E-37 T 10-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 Pfam PF13404 AsnC-type helix-turn-helix domain 31 72 1.3E-16 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 Gene3D G3DSA:3.30.70.920 84 168 1.2E-30 T 10-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain RG49_RS08885 ffd40d65d68d0ceee49c7122e78c01bf 181 Gene3D G3DSA:1.10.10.10 32 83 1.1E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15360 84a0a843d8345d29dbe7cf03877f5f44 616 SUPERFAMILY SSF143975 3 420 4.97E-135 T 10-03-2017 RG49_RS15360 84a0a843d8345d29dbe7cf03877f5f44 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 10-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS15360 84a0a843d8345d29dbe7cf03877f5f44 616 Pfam PF00920 Dehydratase family 34 607 8.1E-219 T 10-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS15360 84a0a843d8345d29dbe7cf03877f5f44 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 10-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS15360 84a0a843d8345d29dbe7cf03877f5f44 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 4.0E-274 T 10-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS15360 84a0a843d8345d29dbe7cf03877f5f44 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 45.42 T 10-03-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS15360 84a0a843d8345d29dbe7cf03877f5f44 616 SUPERFAMILY SSF52016 421 610 5.02E-60 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.15 T 10-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 SUPERFAMILY SSF54814 2 106 1.6E-37 T 10-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 Gene3D G3DSA:3.30.300.20 18 107 1.1E-33 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.6E-100 T 10-03-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 Gene3D G3DSA:3.30.1140.32 108 207 5.9E-48 T 10-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 SMART SM00322 60 125 1.6E-6 T 10-03-2017 IPR004087 K Homology domain GO:0003676 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.8E-41 T 10-03-2017 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 10-03-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 SUPERFAMILY SSF54821 108 206 6.93E-41 T 10-03-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18030 015d00c9b7f7f2897a9ebd700c9a9d69 233 Pfam PF07650 KH domain 38 111 9.5E-19 T 10-03-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS06900 42f0729f16c0ba45bb1517418f0feaa7 421 SUPERFAMILY SSF51197 5 419 4.76E-155 T 10-03-2017 RG49_RS06900 42f0729f16c0ba45bb1517418f0feaa7 421 Pfam PF07350 Protein of unknown function (DUF1479) 16 419 9.6E-144 T 10-03-2017 IPR010856 Protein of unknown function DUF1479 RG49_RS06900 42f0729f16c0ba45bb1517418f0feaa7 421 Gene3D G3DSA:2.60.120.330 4 420 1.5E-162 T 10-03-2017 IPR027443 Isopenicillin N synthase-like RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 SUPERFAMILY SSF47757 14 91 1.05E-23 T 10-03-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 Pfam PF01739 CheR methyltransferase, SAM binding domain 92 280 2.2E-62 T 10-03-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 PIRSF PIRSF000410 10 285 7.4E-105 T 10-03-2017 IPR026024 Chemotaxis protein methyltransferase CheR RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 Gene3D G3DSA:1.10.155.10 14 90 1.6E-33 T 10-03-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 Gene3D G3DSA:3.40.50.150 91 282 3.5E-70 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 PRINTS PR00996 Glutamate methyltransferase family signature 224 238 6.0E-48 T 10-03-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 PRINTS PR00996 Glutamate methyltransferase family signature 85 97 6.0E-48 T 10-03-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 PRINTS PR00996 Glutamate methyltransferase family signature 243 266 6.0E-48 T 10-03-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 PRINTS PR00996 Glutamate methyltransferase family signature 118 138 6.0E-48 T 10-03-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 PRINTS PR00996 Glutamate methyltransferase family signature 46 59 6.0E-48 T 10-03-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 PRINTS PR00996 Glutamate methyltransferase family signature 152 168 6.0E-48 T 10-03-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 SUPERFAMILY SSF53335 92 281 7.12E-61 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 Pfam PF03705 CheR methyltransferase, all-alpha domain 26 77 3.3E-18 T 10-03-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal RG49_RS00490 6f6f430ab9ea53e7d08bd8bd496919f3 286 SMART SM00138 24 284 3.0E-141 T 10-03-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 RG49_RS00980 d43d3119144e53f2b5755e9fa11eeb65 307 Gene3D G3DSA:3.40.190.10 180 264 1.9E-23 T 10-03-2017 RG49_RS00980 d43d3119144e53f2b5755e9fa11eeb65 307 SUPERFAMILY SSF53850 93 300 1.57E-40 T 10-03-2017 RG49_RS00980 d43d3119144e53f2b5755e9fa11eeb65 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.9E-16 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS00980 d43d3119144e53f2b5755e9fa11eeb65 307 Pfam PF03466 LysR substrate binding domain 91 295 2.3E-36 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS00980 d43d3119144e53f2b5755e9fa11eeb65 307 Gene3D G3DSA:1.10.10.10 7 90 7.8E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00980 d43d3119144e53f2b5755e9fa11eeb65 307 Gene3D G3DSA:3.40.190.10 96 179 1.9E-21 T 10-03-2017 RG49_RS00980 d43d3119144e53f2b5755e9fa11eeb65 307 SUPERFAMILY SSF46785 7 90 1.06E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23100 810ed5968ddc5e27d1081642822c0e04 277 PIRSF PIRSF000477 1 276 1.0E-120 T 10-03-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 RG49_RS23100 810ed5968ddc5e27d1081642822c0e04 277 Gene3D G3DSA:3.40.50.1580 15 276 2.4E-92 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS23100 810ed5968ddc5e27d1081642822c0e04 277 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 80 121 - T 10-03-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 RG49_RS23100 810ed5968ddc5e27d1081642822c0e04 277 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 27 272 3.1E-106 T 10-03-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 RG49_RS23100 810ed5968ddc5e27d1081642822c0e04 277 Pfam PF01048 Phosphorylase superfamily 27 273 4.4E-41 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS23100 810ed5968ddc5e27d1081642822c0e04 277 SUPERFAMILY SSF53167 11 275 1.95E-83 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS23100 810ed5968ddc5e27d1081642822c0e04 277 TIGRFAM TIGR01699 XAPA: xanthosine phosphorylase 27 274 5.2E-164 T 10-03-2017 IPR010943 Xanthosine phosphorylase GO:0004731|GO:0005737|GO:0055086 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 111 3.0E-31 T 10-03-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 230 2.9E-92 T 10-03-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 Gene3D G3DSA:3.10.20.30 1 106 1.6E-36 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 Gene3D G3DSA:1.10.1060.10 108 236 3.8E-46 T 10-03-2017 RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 SUPERFAMILY SSF54292 1 106 6.18E-30 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 1.0E-9 T 10-03-2017 RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 SUPERFAMILY SSF46548 107 236 9.07E-40 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS07435 fd8c9643325bacc730ef2556804f8f2a 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS24150 d307ccb7224a87bc3686037bd68ee470 69 Pfam PF04995 Heme exporter protein D (CcmD) 15 58 8.8E-17 T 10-03-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 RG49_RS24150 d307ccb7224a87bc3686037bd68ee470 69 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 12 58 2.2E-19 T 10-03-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 RG49_RS11215 18acf8210d82c9f9aedc74c99466b051 308 SMART SM00382 30 213 3.7E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS11215 18acf8210d82c9f9aedc74c99466b051 308 SUPERFAMILY SSF52540 3 232 2.77E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11215 18acf8210d82c9f9aedc74c99466b051 308 Gene3D G3DSA:3.40.50.300 2 228 3.8E-68 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11215 18acf8210d82c9f9aedc74c99466b051 308 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS11215 18acf8210d82c9f9aedc74c99466b051 308 Pfam PF00005 ABC transporter 21 165 3.0E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 Pfam PF07729 FCD domain 125 246 1.9E-20 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 SMART SM00895 123 247 4.9E-17 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 SMART SM00345 36 95 2.3E-22 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 5.6E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 5.6E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 SUPERFAMILY SSF48008 120 252 2.33E-23 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 SUPERFAMILY SSF46785 28 99 3.8E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 Gene3D G3DSA:1.10.10.10 29 102 2.8E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 Hamap MF_01236 Transcriptional regulator NanR [nanR]. 4 263 59.512 T 10-03-2017 IPR023730 Transcriptional regulator NanR RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 Gene3D G3DSA:1.20.120.530 117 258 1.0E-24 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS18495 f045ac8532b007ba5d1d09a74fe1186e 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 95 9.5E-21 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS13780 4443201c69f83993fd291831999936fe 80 Pfam PF09583 Phage shock protein G (Phageshock_PspG) 1 63 1.1E-25 T 10-03-2017 IPR014318 Phage shock protein, PspG RG49_RS13780 4443201c69f83993fd291831999936fe 80 TIGRFAM TIGR02975 phageshock_pspG: phage shock protein G 2 64 2.2E-26 T 10-03-2017 IPR014318 Phage shock protein, PspG RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 SUPERFAMILY SSF51735 139 304 7.31E-35 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 Gene3D G3DSA:3.40.50.720 166 284 2.5E-34 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 SMART SM00829 10 310 2.8E-4 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 133 4.3E-34 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 Pfam PF00107 Zinc-binding dehydrogenase 173 300 1.5E-25 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 SUPERFAMILY SSF50129 3 172 2.28E-51 T 10-03-2017 IPR011032 GroES-like RG49_RS12150 53d0eb4add68d89802d50faf42d769f8 340 Gene3D G3DSA:3.90.180.10 1 165 4.5E-56 T 10-03-2017 IPR011032 GroES-like RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 Gene3D G3DSA:3.30.300.30 495 606 5.7E-26 T 10-03-2017 RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 57 8.4E-22 T 10-03-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 Pfam PF00501 AMP-binding enzyme 59 500 9.1E-80 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 Gene3D G3DSA:3.40.50.980 53 240 1.1E-35 T 10-03-2017 RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 Pfam PF13193 AMP-binding enzyme C-terminal domain 509 592 5.0E-24 T 10-03-2017 IPR025110 AMP-binding enzyme C-terminal domain RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 Gene3D G3DSA:3.40.50.980 241 396 8.5E-27 T 10-03-2017 RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 1 628 0.0 T 10-03-2017 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 SUPERFAMILY SSF56801 4 620 5.23E-157 T 10-03-2017 RG49_RS09465 9d4278ad64c2a31e39aa363e41f7a8eb 628 Gene3D G3DSA:2.30.38.10 410 490 3.9E-5 T 10-03-2017 RG49_RS22410 09f9c8a98471672eae8a4f00a1503757 246 SUPERFAMILY SSF75217 4 164 8.5E-40 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS22410 09f9c8a98471672eae8a4f00a1503757 246 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 241 3.2E-97 T 10-03-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 RG49_RS22410 09f9c8a98471672eae8a4f00a1503757 246 PIRSF PIRSF004808 1 245 8.0E-81 T 10-03-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 RG49_RS22410 09f9c8a98471672eae8a4f00a1503757 246 Gene3D G3DSA:3.40.1280.10 4 172 1.7E-33 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS22410 09f9c8a98471672eae8a4f00a1503757 246 Pfam PF00588 SpoU rRNA Methylase family 5 154 1.2E-33 T 10-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 Pfam PF09383 NIL domain 268 339 3.8E-20 T 10-03-2017 IPR018449 NIL domain RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 Gene3D G3DSA:3.30.70.260 238 343 5.7E-32 T 10-03-2017 RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 Pfam PF00005 ABC transporter 21 169 5.6E-37 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 SMART SM00930 265 340 9.8E-25 T 10-03-2017 IPR018449 NIL domain RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 TIGRFAM TIGR02314 ABC_MetN: D-methionine ABC transporter, ATP-binding protein 1 343 3.4E-212 T 10-03-2017 IPR012692 ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria GO:0005524|GO:0009276|GO:0048473|GO:0048474 RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 SUPERFAMILY SSF52540 1 240 1.2E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 SUPERFAMILY SSF55021 248 343 1.49E-26 T 10-03-2017 RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 SMART SM00382 30 218 2.2E-15 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS10815 f475495f01e3e555d3e1655f94c8fe13 343 Gene3D G3DSA:3.40.50.300 1 237 1.1E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10355 161b19735e4c6136e5c42ab02d522d97 329 SMART SM00507 246 295 1.9E-5 T 10-03-2017 IPR003615 HNH nuclease RG49_RS10355 161b19735e4c6136e5c42ab02d522d97 329 Pfam PF06147 Protein of unknown function (DUF968) 129 326 8.4E-88 T 10-03-2017 IPR010373 Protein of unknown function DUF968 RG49_RS16520 85bfac63da9857955bf9396fcbfc8949 512 SUPERFAMILY SSF53720 21 505 8.9E-162 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS16520 85bfac63da9857955bf9396fcbfc8949 512 Gene3D G3DSA:3.40.309.10 299 476 1.1E-56 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS16520 85bfac63da9857955bf9396fcbfc8949 512 Gene3D G3DSA:3.40.605.10 22 298 1.2E-101 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS16520 85bfac63da9857955bf9396fcbfc8949 512 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 300 311 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS16520 85bfac63da9857955bf9396fcbfc8949 512 Pfam PF00171 Aldehyde dehydrogenase family 33 498 1.8E-164 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS16520 85bfac63da9857955bf9396fcbfc8949 512 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS12100 9275abf7fde88fe40130e119257c38ba 78 Pfam PF07256 Protein of unknown function (DUF1435) 1 75 2.8E-32 T 10-03-2017 IPR009885 Protein of unknown function DUF1435 RG49_RS12100 9275abf7fde88fe40130e119257c38ba 78 ProDom PD058594 MEMBRANE INNER C5447 MAJOR ECS5328 THE SUPERFAMILY PERMEASES STY4905 YJJZ 1 78 1.0E-30 T 10-03-2017 IPR009885 Protein of unknown function DUF1435 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 PRINTS PR00834 HtrA/DegQ protease family signature 221 238 8.3E-59 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 PRINTS PR00834 HtrA/DegQ protease family signature 199 216 8.3E-59 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 PRINTS PR00834 HtrA/DegQ protease family signature 102 114 8.3E-59 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 PRINTS PR00834 HtrA/DegQ protease family signature 123 143 8.3E-59 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 PRINTS PR00834 HtrA/DegQ protease family signature 164 188 8.3E-59 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 PRINTS PR00834 HtrA/DegQ protease family signature 307 319 8.3E-59 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 SMART SM00228 267 349 3.6E-13 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 SMART SM00228 374 447 1.8E-11 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 Gene3D G3DSA:2.30.42.10 269 364 1.6E-29 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 Pfam PF13180 PDZ domain 285 358 1.6E-17 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 Gene3D G3DSA:2.40.10.10 39 154 1.9E-34 T 10-03-2017 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 Pfam PF13365 Trypsin-like peptidase domain 92 228 8.6E-30 T 10-03-2017 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 Gene3D G3DSA:2.30.42.10 387 452 3.6E-17 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 SUPERFAMILY SSF50156 225 350 1.18E-23 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 41 453 2.3E-160 T 10-03-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 Gene3D G3DSA:2.40.10.10 156 268 1.6E-43 T 10-03-2017 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 SUPERFAMILY SSF50156 386 452 1.84E-15 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 SUPERFAMILY SSF50494 39 262 6.15E-63 T 10-03-2017 IPR009003 Peptidase S1, PA clan RG49_RS18450 6c89d1124e197cfdfd2b3ffa959812e4 455 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 373 443 2.1E-12 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS20480 bf4496a7b8f069bc64a4e85cbc7ed61f 162 SUPERFAMILY SSF54862 4 155 4.29E-41 T 10-03-2017 RG49_RS20480 bf4496a7b8f069bc64a4e85cbc7ed61f 162 Gene3D G3DSA:3.30.70.20 94 128 3.3E-10 T 10-03-2017 RG49_RS20480 bf4496a7b8f069bc64a4e85cbc7ed61f 162 Pfam PF13247 4Fe-4S dicluster domain 51 140 5.0E-13 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS20480 bf4496a7b8f069bc64a4e85cbc7ed61f 162 Gene3D G3DSA:3.30.70.20 63 93 8.5E-17 T 10-03-2017 RG49_RS20480 bf4496a7b8f069bc64a4e85cbc7ed61f 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS20480 bf4496a7b8f069bc64a4e85cbc7ed61f 162 Gene3D G3DSA:3.30.70.20 4 62 4.0E-19 T 10-03-2017 RG49_RS20480 bf4496a7b8f069bc64a4e85cbc7ed61f 162 Gene3D G3DSA:3.30.70.20 129 154 4.0E-19 T 10-03-2017 RG49_RS05190 982e8fe64b3c7e5a1ad44dbbd2c9d022 317 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 317 70.49 T 10-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 RG49_RS05190 982e8fe64b3c7e5a1ad44dbbd2c9d022 317 SUPERFAMILY SSF53901 3 317 1.35E-71 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS05190 982e8fe64b3c7e5a1ad44dbbd2c9d022 317 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 228 316 5.0E-37 T 10-03-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 RG49_RS05190 982e8fe64b3c7e5a1ad44dbbd2c9d022 317 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 317 6.8E-152 T 10-03-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 RG49_RS05190 982e8fe64b3c7e5a1ad44dbbd2c9d022 317 Gene3D G3DSA:3.40.47.10 161 316 4.4E-53 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS05190 982e8fe64b3c7e5a1ad44dbbd2c9d022 317 Gene3D G3DSA:3.40.47.10 1 160 2.5E-65 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS05190 982e8fe64b3c7e5a1ad44dbbd2c9d022 317 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 1.8E-29 T 10-03-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 SUPERFAMILY SSF46609 1 90 7.99E-37 T 10-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 168 175 - T 10-03-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 Gene3D G3DSA:1.10.287.990 20 90 1.8E-32 T 10-03-2017 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 SUPERFAMILY SSF54719 95 204 1.44E-45 T 10-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 PIRSF PIRSF000349 1 206 7.6E-81 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.7E-27 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 2.7E-27 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.7E-27 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 2.7E-27 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 PRINTS PR01703 Manganese superoxide dismutase signature 166 178 2.7E-27 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 1.1E-33 T 10-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS14605 cb6808d5a0d33d22ae7d2deec5072311 206 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 201 4.4E-41 T 10-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 Gene3D G3DSA:3.40.50.720 1 90 5.7E-41 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 361 7.2E-10 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 Gene3D G3DSA:3.90.190.20 313 449 2.1E-37 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 Pfam PF01225 Mur ligase family, catalytic domain 2 101 4.7E-20 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 SUPERFAMILY SSF53623 95 308 1.44E-48 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 449 2.3E-276 T 10-03-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 450 59.577 T 10-03-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 Gene3D G3DSA:3.40.1190.10 92 312 2.9E-83 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 SUPERFAMILY SSF53244 312 447 4.45E-37 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 SUPERFAMILY SSF51984 1 90 1.31E-24 T 10-03-2017 RG49_RS12730 6b35dd90051a99c50a20aa701f4f85c3 457 Pfam PF08245 Mur ligase middle domain 108 291 2.6E-18 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS21135 b60b0b68dbe3564a1262cfea82549c27 82 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 51 7.4E-12 T 10-03-2017 IPR007159 SpoVT-AbrB domain GO:0003677 RG49_RS21135 b60b0b68dbe3564a1262cfea82549c27 82 SUPERFAMILY SSF89447 4 75 5.58E-22 T 10-03-2017 RG49_RS21135 b60b0b68dbe3564a1262cfea82549c27 82 SMART SM00966 7 52 7.5E-11 T 10-03-2017 IPR007159 SpoVT-AbrB domain GO:0003677 RG49_RS21135 b60b0b68dbe3564a1262cfea82549c27 82 Gene3D G3DSA:2.10.260.10 1 82 2.9E-30 T 10-03-2017 RG49_RS24815 cd0e91f121358e0a93f7ac904a28d684 219 PIRSF PIRSF020634 17 219 4.2E-98 T 10-03-2017 IPR011392 Tellurite resistance, TerY RG49_RS24815 cd0e91f121358e0a93f7ac904a28d684 219 SUPERFAMILY SSF53300 22 174 1.39E-19 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS24815 cd0e91f121358e0a93f7ac904a28d684 219 Pfam PF00092 von Willebrand factor type A domain 24 173 4.5E-10 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS24815 cd0e91f121358e0a93f7ac904a28d684 219 SMART SM00327 19 193 4.1E-18 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS24815 cd0e91f121358e0a93f7ac904a28d684 219 Gene3D G3DSA:3.40.50.410 23 173 3.3E-11 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS06095 efb6fc75764a33cf4b11b58cea72ca76 215 SUPERFAMILY SSF56281 2 209 1.62E-60 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS06095 efb6fc75764a33cf4b11b58cea72ca76 215 Gene3D G3DSA:3.60.15.10 2 210 9.9E-67 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS06095 efb6fc75764a33cf4b11b58cea72ca76 215 SMART SM00849 12 192 6.9E-44 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS06095 efb6fc75764a33cf4b11b58cea72ca76 215 Pfam PF00753 Metallo-beta-lactamase superfamily 10 192 1.4E-33 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS14110 008d79e35bd2270915d40e060cca3867 158 Hamap MF_01181 Regulator of sigma D [rsd]. 1 151 41.283 T 10-03-2017 IPR023785 Regulator of RNA polymerase sigma(70) subunit, Rsd RG49_RS14110 008d79e35bd2270915d40e060cca3867 158 PIRSF PIRSF016548 1 158 4.4E-63 T 10-03-2017 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 RG49_RS14110 008d79e35bd2270915d40e060cca3867 158 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 1 147 8.1E-53 T 10-03-2017 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 RG49_RS24570 0bb06abefb7a983ecb06cf9748e23ca6 153 PIRSF PIRSF006187 1 153 6.3E-59 T 10-03-2017 IPR009736 Protein of unknown function DUF1307 RG49_RS24570 0bb06abefb7a983ecb06cf9748e23ca6 153 SUPERFAMILY SSF160704 24 153 7.98E-40 T 10-03-2017 IPR009736 Protein of unknown function DUF1307 RG49_RS24570 0bb06abefb7a983ecb06cf9748e23ca6 153 Pfam PF06998 Protein of unknown function (DUF1307) 28 150 1.3E-41 T 10-03-2017 IPR009736 Protein of unknown function DUF1307 RG49_RS24570 0bb06abefb7a983ecb06cf9748e23ca6 153 Gene3D G3DSA:3.30.1830.10 27 153 1.3E-45 T 10-03-2017 IPR009736 Protein of unknown function DUF1307 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 317 33.044 T 10-03-2017 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 Gene3D G3DSA:2.30.30.100 271 320 2.8E-24 T 10-03-2017 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 Gene3D G3DSA:3.30.930.10 71 269 9.7E-59 T 10-03-2017 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 SUPERFAMILY SSF55681 69 268 6.71E-59 T 10-03-2017 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 81 317 4.7E-87 T 10-03-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 Pfam PF02237 Biotin protein ligase C terminal domain 271 317 1.2E-11 T 10-03-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 6 76 3.0E-31 T 10-03-2017 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 SUPERFAMILY SSF46785 3 60 5.56E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 Pfam PF03099 Biotin/lipoate A/B protein ligase family 84 208 4.9E-26 T 10-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 SUPERFAMILY SSF50037 271 317 7.32E-11 T 10-03-2017 IPR008988 Transcriptional repressor, C-terminal RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 Pfam PF08279 HTH domain 9 58 9.0E-13 T 10-03-2017 IPR013196 Helix-turn-helix, type 11 RG49_RS14235 c0d9e6ec96b769dfbd45937bfaf17845 321 Gene3D G3DSA:1.10.10.10 1 63 9.3E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12045 641b094eec9c13e543b311f76ec6fb3d 53 PIRSF PIRSF036466 1 53 8.3E-21 T 10-03-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 RG49_RS12045 641b094eec9c13e543b311f76ec6fb3d 53 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 2.0E-13 T 10-03-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 RG49_RS12045 641b094eec9c13e543b311f76ec6fb3d 53 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 52 19.041 T 10-03-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 10-03-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 Gene3D G3DSA:3.20.20.70 7 244 7.4E-82 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 PIRSF PIRSF006621 1 321 1.6E-99 T 10-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 Pfam PF01207 Dihydrouridine synthase (Dus) 14 318 6.5E-117 T 10-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 SUPERFAMILY SSF51395 10 319 1.83E-87 T 10-03-2017 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 Gene3D G3DSA:1.10.1200.80 252 319 2.6E-17 T 10-03-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 320 5.2E-143 T 10-03-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 RG49_RS18305 b4444db13d93a430c75b1f22d9459e45 321 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 49.407 T 10-03-2017 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 SUPERFAMILY SSF52518 357 557 8.11E-60 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 Gene3D G3DSA:3.40.50.970 1 172 2.4E-51 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 Gene3D G3DSA:3.40.50.1220 185 341 2.7E-43 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 10-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 525 2.9E-40 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 319 1.1E-29 T 10-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 9.0E-42 T 10-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 SUPERFAMILY SSF52518 2 174 5.9E-43 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 Gene3D G3DSA:3.40.50.970 350 550 3.7E-61 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS06405 9179b0c0c547accff39e6304517a2ee7 572 SUPERFAMILY SSF52467 182 352 6.1E-43 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 SMART SM00357 5 69 9.3E-31 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 PIRSF PIRSF002599 1 69 7.1E-26 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 2.9E-33 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 Gene3D G3DSA:2.40.50.140 4 67 2.7E-32 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 SUPERFAMILY SSF50249 3 68 3.26E-26 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 PRINTS PR00050 Cold shock protein signature 42 60 1.1E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 PRINTS PR00050 Cold shock protein signature 27 36 1.1E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 PRINTS PR00050 Cold shock protein signature 6 21 1.1E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS00845 2438b21594d2be1ec72263acfe9ba76f 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS04220 fb331d0f2eb123ca5755919060e8b4d3 349 SUPERFAMILY SSF52096 100 209 3.02E-33 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS04220 fb331d0f2eb123ca5755919060e8b4d3 349 SUPERFAMILY SSF52096 240 299 3.02E-33 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS04220 fb331d0f2eb123ca5755919060e8b4d3 349 Pfam PF08496 Peptidase family S49 N-terminal 2 158 2.3E-62 T 10-03-2017 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 RG49_RS04220 fb331d0f2eb123ca5755919060e8b4d3 349 Gene3D G3DSA:3.90.226.10 271 306 3.9E-37 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS04220 fb331d0f2eb123ca5755919060e8b4d3 349 Gene3D G3DSA:3.90.226.10 98 205 3.9E-37 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS04220 fb331d0f2eb123ca5755919060e8b4d3 349 Pfam PF01343 Peptidase family S49 161 310 5.5E-51 T 10-03-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 190 201 - T 10-03-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 SUPERFAMILY SSF53335 9 312 4.94E-68 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 43 312 5.6E-117 T 10-03-2017 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 Hamap MF_01579 Ribosomal RNA small subunit methyltransferase F [rsmF]. 8 477 65.979 T 10-03-2017 IPR023545 rRNA small subunit methyltransferase F GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 241 257 3.3E-28 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 295 312 3.3E-28 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 191 203 3.3E-28 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 124 134 3.3E-28 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 93 107 3.3E-28 T 10-03-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 Gene3D G3DSA:3.40.50.150 104 312 9.8E-59 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 10 107 8.8E-29 T 10-03-2017 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 Pfam PF01189 16S rRNA methyltransferase RsmB/F 120 311 4.7E-46 T 10-03-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS00775 e101451c4d701a3017da9f92e9b758ad 481 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 423 472 2.0E-9 T 10-03-2017 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 SMART SM00155 384 411 3.4E-7 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 SMART SM00155 145 172 0.013 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 Pfam PF13091 PLD-like domain 295 437 1.2E-27 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 Pfam PF13091 PLD-like domain 59 204 8.3E-15 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 Gene3D G3DSA:3.30.870.10 212 458 1.5E-62 T 10-03-2017 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 Gene3D G3DSA:3.30.870.10 11 207 4.5E-47 T 10-03-2017 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 SUPERFAMILY SSF56024 34 212 1.41E-39 T 10-03-2017 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 Hamap MF_01918 Cardiolipin synthase C [clsC]. 60 493 74.269 T 10-03-2017 IPR030871 Cardiolipin synthase C GO:0032049|GO:0090483 RG49_RS05420 d482b6b40107d62a46382b55b445fb97 493 SUPERFAMILY SSF56024 225 457 1.95E-36 T 10-03-2017 RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 Pfam PF01726 LexA DNA binding domain 1 65 1.3E-31 T 10-03-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 Hamap MF_00015 LexA repressor [lexA]. 3 199 32.817 T 10-03-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 SUPERFAMILY SSF51306 76 198 1.27E-38 T 10-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 Gene3D G3DSA:1.10.10.10 1 69 7.0E-30 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 Gene3D G3DSA:2.10.109.10 76 198 2.8E-47 T 10-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 TIGRFAM TIGR00498 lexA: repressor LexA 1 199 3.2E-87 T 10-03-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 122 133 2.4E-14 T 10-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 111 121 2.4E-14 T 10-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 150 162 2.4E-14 T 10-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 SUPERFAMILY SSF46785 3 70 6.28E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13815 0f8aa8f591e0c3d6aa927c9a32cd25c9 202 Pfam PF00717 Peptidase S24-like 114 180 6.4E-16 T 10-03-2017 IPR019759 Peptidase S24/S26A/S26B RG49_RS02410 986a928fceb003a0f7a1e508424319cb 91 Gene3D G3DSA:2.40.10.210 23 91 2.2E-37 T 10-03-2017 RG49_RS02410 986a928fceb003a0f7a1e508424319cb 91 Pfam PF13856 ATP-binding sugar transporter from pro-phage 1 88 7.5E-15 T 10-03-2017 IPR025601 ATP-binding sugar transporter-like protein RG49_RS02410 986a928fceb003a0f7a1e508424319cb 91 SUPERFAMILY SSF69279 1 91 1.7E-34 T 10-03-2017 RG49_RS12300 128ec01786554e77d03d2387cda88fd9 318 Pfam PF04754 Putative transposase, YhgA-like 8 210 2.2E-88 T 10-03-2017 IPR006842 Transposase (putative), YhgA-like RG49_RS12300 128ec01786554e77d03d2387cda88fd9 318 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 301 5.7E-50 T 10-03-2017 IPR010106 Conserved hypothetical protein CHP01784 RG49_RS20645 357da97f78a32242bf86a9c2ab848e64 255 TIGRFAM TIGR01401 fliR_like_III: type III secretion apparatus protein SpaR/YscT/HrcT 7 253 9.8E-99 T 10-03-2017 IPR006304 Type III secretion protein SpaR/YscT GO:0006810|GO:0016021 RG49_RS20645 357da97f78a32242bf86a9c2ab848e64 255 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 200 219 1.8E-22 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS20645 357da97f78a32242bf86a9c2ab848e64 255 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 178 200 1.8E-22 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS20645 357da97f78a32242bf86a9c2ab848e64 255 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.8E-22 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS20645 357da97f78a32242bf86a9c2ab848e64 255 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 80 99 1.8E-22 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS20645 357da97f78a32242bf86a9c2ab848e64 255 Pfam PF01311 Bacterial export proteins, family 1 14 235 3.0E-47 T 10-03-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 RG49_RS16240 2981d5ca220680357e8e456532a32d93 356 Gene3D G3DSA:3.40.50.2000 6 154 1.1E-38 T 10-03-2017 RG49_RS16240 2981d5ca220680357e8e456532a32d93 356 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 77 326 2.7E-81 T 10-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 RG49_RS16240 2981d5ca220680357e8e456532a32d93 356 Gene3D G3DSA:3.40.50.2000 173 344 1.2E-46 T 10-03-2017 RG49_RS16240 2981d5ca220680357e8e456532a32d93 356 TIGRFAM TIGR02201 heptsyl_trn_III: putative lipopolysaccharide heptosyltransferase III 7 344 8.6E-152 T 10-03-2017 IPR011916 Lipopolysaccharide heptosyltransferase III, putative RG49_RS16240 2981d5ca220680357e8e456532a32d93 356 SUPERFAMILY SSF53756 6 345 1.82E-79 T 10-03-2017 RG49_RS19805 488b64d8d7d1d62b8dc4c69da2641139 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 1.9E-31 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS19805 488b64d8d7d1d62b8dc4c69da2641139 113 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 10-03-2017 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site RG49_RS19805 488b64d8d7d1d62b8dc4c69da2641139 113 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 113 24.164 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS19805 488b64d8d7d1d62b8dc4c69da2641139 113 PIRSF PIRSF004761 1 113 1.2E-36 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS19805 488b64d8d7d1d62b8dc4c69da2641139 113 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 113 1.6E-44 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS10625 b311f79e15fa7d1b13d76e8d5960376a 166 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 8 160 1.8E-51 T 10-03-2017 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 RG49_RS10625 b311f79e15fa7d1b13d76e8d5960376a 166 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 7 161 4.7E-51 T 10-03-2017 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 RG49_RS10625 b311f79e15fa7d1b13d76e8d5960376a 166 PIRSF PIRSF028301 1 166 7.4E-59 T 10-03-2017 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 10-03-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 PIRSF PIRSF039144 1 112 6.2E-53 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 SUPERFAMILY SSF54913 1 112 4.13E-42 T 10-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 10-03-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 Gene3D G3DSA:3.30.70.120 1 112 1.3E-47 T 10-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 SMART SM00938 4 105 6.4E-61 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 PRINTS PR00340 P-II protein signature 2 17 2.8E-41 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 PRINTS PR00340 P-II protein signature 83 103 2.8E-41 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 PRINTS PR00340 P-II protein signature 52 75 2.8E-41 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 PRINTS PR00340 P-II protein signature 23 41 2.8E-41 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS08870 2c10f8c51446d7159794c9595ed25026 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.9E-41 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 SUPERFAMILY SSF51703 4 542 7.85E-221 T 10-03-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 583 713 1.5E-65 T 10-03-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 Pfam PF02310 B12 binding domain 586 699 8.7E-16 T 10-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 SUPERFAMILY SSF52242 555 713 9.42E-56 T 10-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 547 2.5E-283 T 10-03-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 370 395 - T 10-03-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 Pfam PF01642 Methylmalonyl-CoA mutase 28 539 1.5E-236 T 10-03-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 Gene3D G3DSA:3.40.50.280 553 711 3.3E-68 T 10-03-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 RG49_RS20305 f3126b331c87c32b2508ea259d60c90b 714 Gene3D G3DSA:3.20.20.240 27 493 1.5E-208 T 10-03-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 RG49_RS15015 8f5dbbc9c3b11a9b12031fee80283b10 201 Pfam PF02036 SCP-2 sterol transfer family 15 112 6.2E-21 T 10-03-2017 IPR003033 SCP2 sterol-binding domain RG49_RS15015 8f5dbbc9c3b11a9b12031fee80283b10 201 SUPERFAMILY SSF55718 12 111 2.85E-7 T 10-03-2017 IPR003033 SCP2 sterol-binding domain RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 258 1.5E-51 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 210 232 - T 10-03-2017 RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 Hamap MF_01847 HMP-PP phosphatase [cof]. 1 272 63.104 T 10-03-2017 IPR023938 HMP-PP phosphatase GO:0016818 RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 Gene3D G3DSA:3.30.1240.10 98 174 6.2E-13 T 10-03-2017 RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 Gene3D G3DSA:3.40.50.1000 2 72 6.0E-45 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 Gene3D G3DSA:3.40.50.1000 175 263 6.0E-45 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 258 2.8E-62 T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 SUPERFAMILY SSF56784 1 262 8.03E-60 T 10-03-2017 IPR023214 HAD-like domain RG49_RS08890 6a868667be2f869d1f5a3adeb0eca635 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 229 3.0E-46 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 SUPERFAMILY SSF53822 63 316 1.16E-59 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 Gene3D G3DSA:3.40.50.2300 174 330 1.8E-44 T 10-03-2017 RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 SUPERFAMILY SSF47413 5 62 5.63E-13 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 52 7.8E-18 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 Gene3D G3DSA:3.40.50.2300 62 173 1.2E-40 T 10-03-2017 RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 Gene3D G3DSA:1.10.260.40 4 59 1.1E-16 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 64 309 9.3E-30 T 10-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 10-03-2017 RG49_RS17385 6bcc63c46e62a5b88fbf3bcbd62cad68 331 SMART SM00354 5 75 2.0E-26 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS23735 4e3a899534f28d51cb083b0e0b33ff72 323 SUPERFAMILY SSF53187 247 320 2.51E-42 T 10-03-2017 RG49_RS23735 4e3a899534f28d51cb083b0e0b33ff72 323 SUPERFAMILY SSF53187 38 217 2.51E-42 T 10-03-2017 RG49_RS23735 4e3a899534f28d51cb083b0e0b33ff72 323 Gene3D G3DSA:3.40.630.10 35 321 4.5E-44 T 10-03-2017 RG49_RS23735 4e3a899534f28d51cb083b0e0b33ff72 323 Pfam PF04389 Peptidase family M28 95 317 2.4E-23 T 10-03-2017 IPR007484 Peptidase M28 RG49_RS01195 3615410c0dcb65f92791e942145bfee2 135 SUPERFAMILY SSF55811 1 125 1.49E-36 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS01195 3615410c0dcb65f92791e942145bfee2 135 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS01195 3615410c0dcb65f92791e942145bfee2 135 Gene3D G3DSA:3.90.79.10 3 127 5.0E-34 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS01195 3615410c0dcb65f92791e942145bfee2 135 Pfam PF00293 NUDIX domain 5 125 1.1E-21 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS01195 3615410c0dcb65f92791e942145bfee2 135 PRINTS PR00502 NUDIX hydrolase family signature 46 61 3.8E-6 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS01195 3615410c0dcb65f92791e942145bfee2 135 PRINTS PR00502 NUDIX hydrolase family signature 32 46 3.8E-6 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS20455 1ce95b1121217c21a7bcb657892883a4 182 Gene3D G3DSA:3.90.79.10 1 166 1.7E-45 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS20455 1ce95b1121217c21a7bcb657892883a4 182 Pfam PF00293 NUDIX domain 31 161 1.4E-19 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS20455 1ce95b1121217c21a7bcb657892883a4 182 SUPERFAMILY SSF55811 4 167 2.03E-51 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS20455 1ce95b1121217c21a7bcb657892883a4 182 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 4 177 34.253 T 10-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 RG49_RS20455 1ce95b1121217c21a7bcb657892883a4 182 PIRSF PIRSF018427 1 181 8.3E-58 T 10-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 RG49_RS20455 1ce95b1121217c21a7bcb657892883a4 182 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 6 165 4.4E-46 T 10-03-2017 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 SUPERFAMILY SSF51604 95 359 4.85E-72 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 8.3E-31 T 10-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 SUPERFAMILY SSF54826 1 112 1.41E-32 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 Gene3D G3DSA:3.20.20.120 117 341 1.5E-76 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 Hamap MF_01289 D-galactonate dehydratase [dgoD]. 1 382 76.497 T 10-03-2017 IPR023592 D-galactonate dehydratase GO:0008869|GO:0034194 KEGG: 00052+4.2.1.6 RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 Pfam PF13378 Enolase C-terminal domain-like 135 355 2.3E-53 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 Gene3D G3DSA:3.30.390.10 1 116 4.2E-54 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS15765 20f489df41748a3a8ac5f92d8bccfd75 382 SMART SM00922 125 230 1.0E-17 T 10-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal RG49_RS07935 24eac8a537c66db23cb62001a53e7a53 370 Pfam PF01098 Cell cycle protein 20 364 1.6E-125 T 10-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 RG49_RS07935 24eac8a537c66db23cb62001a53e7a53 370 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 17 364 3.6E-137 T 10-03-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 RG49_RS07935 24eac8a537c66db23cb62001a53e7a53 370 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 10-03-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 SUPERFAMILY SSF53623 105 322 8.11E-75 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 Gene3D G3DSA:3.40.1190.10 108 325 2.6E-86 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 SUPERFAMILY SSF51984 20 106 2.88E-29 T 10-03-2017 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 Gene3D G3DSA:3.40.50.720 20 107 1.5E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 Pfam PF08245 Mur ligase middle domain 124 304 5.7E-28 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 Pfam PF01225 Mur ligase family, catalytic domain 21 118 9.0E-30 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 SUPERFAMILY SSF53244 323 476 4.94E-44 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 327 418 1.7E-19 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 Gene3D G3DSA:3.90.190.20 326 477 7.3E-54 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 19 481 43.416 T 10-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11400 21aba3a2a5bc6bc345078a518cfd0e17 491 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 21 475 9.9E-184 T 10-03-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS15160 361a48ee9873e2216b08d9cc6b57f9e9 106 Pfam PF01491 Frataxin-like domain 1 102 1.3E-30 T 10-03-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 RG49_RS15160 361a48ee9873e2216b08d9cc6b57f9e9 106 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 105 4.7E-44 T 10-03-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 RG49_RS15160 361a48ee9873e2216b08d9cc6b57f9e9 106 Hamap MF_00142 Protein CyaY [cyaY]. 1 105 29.262 T 10-03-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 RG49_RS15160 361a48ee9873e2216b08d9cc6b57f9e9 106 ProSitePatterns PS01344 Frataxin family signature. 50 64 - T 10-03-2017 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 RG49_RS15160 361a48ee9873e2216b08d9cc6b57f9e9 106 SMART SM01219 1 106 1.7E-57 T 10-03-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 RG49_RS15160 361a48ee9873e2216b08d9cc6b57f9e9 106 SUPERFAMILY SSF55387 1 105 1.29E-40 T 10-03-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 RG49_RS15160 361a48ee9873e2216b08d9cc6b57f9e9 106 Gene3D G3DSA:3.30.920.10 1 105 3.5E-37 T 10-03-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 Pfam PF01264 Chorismate synthase 10 345 1.7E-143 T 10-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.927 T 10-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 10-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 PIRSF PIRSF001456 3 359 2.5E-142 T 10-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 2.2E-140 T 10-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 Gene3D G3DSA:3.60.150.10 9 352 1.3E-161 T 10-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 10-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 SUPERFAMILY SSF103263 4 353 1.96E-149 T 10-03-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS23430 48e6499ecd1bd82dfa8d2b0ca019d341 361 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 10-03-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 RG49_RS17780 0118bda499a4dd9ff64043bbdfbda1f3 55 Pfam PF10832 Protein of unknown function (DUF2559) 2 55 5.2E-31 T 10-03-2017 IPR022541 Protein of unknown function DUF2559 RG49_RS17780 0118bda499a4dd9ff64043bbdfbda1f3 55 ProDom PD026929 YHFG 1 55 5.0E-15 T 10-03-2017 IPR022541 Protein of unknown function DUF2559 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 Gene3D G3DSA:1.20.1080.10 2 229 8.6E-68 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 SUPERFAMILY SSF81338 2 228 3.01E-67 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 Pfam PF00230 Major intrinsic protein 2 223 2.2E-49 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 ProSitePatterns PS00221 MIP family signature. 61 69 - T 10-03-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 Hamap MF_01146 Aquaporin Z [aqpZ]. 2 230 35.782 T 10-03-2017 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 223 1.2E-63 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 PRINTS PR00783 Major intrinsic protein family signature 167 189 6.5E-49 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 PRINTS PR00783 Major intrinsic protein family signature 43 67 6.5E-49 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 PRINTS PR00783 Major intrinsic protein family signature 206 226 6.5E-49 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 PRINTS PR00783 Major intrinsic protein family signature 3 22 6.5E-49 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 PRINTS PR00783 Major intrinsic protein family signature 80 99 6.5E-49 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS06380 29786e341a0244c771452f53e29cfce5 231 PRINTS PR00783 Major intrinsic protein family signature 137 155 6.5E-49 T 10-03-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 RG49_RS12970 314591b91befac6a39f706b263eabdaa 95 Pfam PF07338 Protein of unknown function (DUF1471) 39 94 2.0E-18 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS12970 314591b91befac6a39f706b263eabdaa 95 SUPERFAMILY SSF159871 15 94 1.57E-18 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS12970 314591b91befac6a39f706b263eabdaa 95 Gene3D G3DSA:3.30.1660.10 37 94 2.7E-15 T 10-03-2017 IPR025543 Dodecin-like RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 6 166 1.1E-40 T 10-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 Gene3D G3DSA:3.40.50.720 6 260 1.1E-85 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 PRINTS PR00084 Mannitol dehydrogenase signature 7 17 1.4E-16 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 PRINTS PR00084 Mannitol dehydrogenase signature 157 170 1.4E-16 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 PRINTS PR00084 Mannitol dehydrogenase signature 197 210 1.4E-16 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 PRINTS PR00084 Mannitol dehydrogenase signature 227 242 1.4E-16 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 Gene3D G3DSA:1.10.1040.10 263 451 6.2E-51 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 SUPERFAMILY SSF51735 5 260 1.93E-73 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 196 439 1.2E-83 T 10-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 RG49_RS24730 cf47eebd5a0bbc2c5133eb9534e17114 455 SUPERFAMILY SSF48179 263 451 2.18E-44 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS10580 238b3de0b3c2ef07111adecfc93154ab 157 Pfam PF08816 Inhibitor of vertebrate lysozyme (Ivy) 39 152 1.2E-34 T 10-03-2017 RG49_RS10580 238b3de0b3c2ef07111adecfc93154ab 157 Gene3D G3DSA:3.40.1420.10 29 157 3.3E-57 T 10-03-2017 IPR014453 Inhibitor of vertebrate lysozyme GO:0042597|GO:0043086 RG49_RS10580 238b3de0b3c2ef07111adecfc93154ab 157 PIRSF PIRSF009103 1 154 8.8E-58 T 10-03-2017 IPR014453 Inhibitor of vertebrate lysozyme GO:0042597|GO:0043086 RG49_RS10580 238b3de0b3c2ef07111adecfc93154ab 157 SUPERFAMILY SSF89872 31 156 1.16E-49 T 10-03-2017 IPR014453 Inhibitor of vertebrate lysozyme GO:0042597|GO:0043086 RG49_RS14590 0e1d6ce8bef6013b4daf7937e83b55fb 327 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 14 327 5.0E-136 T 10-03-2017 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 RG49_RS14590 0e1d6ce8bef6013b4daf7937e83b55fb 327 TIGRFAM TIGR00793 kdgT: 2-keto-3-deoxygluconate transporter 1 314 3.4E-186 T 10-03-2017 IPR018395 2-keto-3-deoxygluconate permease, subgroup GO:0008643|GO:0015649|GO:0016021|GO:0046411 RG49_RS14590 0e1d6ce8bef6013b4daf7937e83b55fb 327 Pfam PF03812 2-keto-3-deoxygluconate permease 3 312 5.4E-115 T 10-03-2017 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 RG49_RS14590 0e1d6ce8bef6013b4daf7937e83b55fb 327 Hamap MF_00070 2-keto-3-deoxygluconate permease [kdgT]. 1 318 41.545 T 10-03-2017 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Gene3D G3DSA:2.30.30.40 597 640 7.9E-25 T 10-03-2017 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Gene3D G3DSA:2.30.30.40 509 530 7.9E-25 T 10-03-2017 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SMART SM00260 501 641 2.9E-46 T 10-03-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SMART SM01231 261 324 2.7E-21 T 10-03-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SUPERFAMILY SSF47226 5 126 2.59E-33 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Gene3D G3DSA:2.40.50.180 533 596 3.2E-15 T 10-03-2017 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SMART SM00073 5 102 3.4E-35 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 487 2.1E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 506 2.1E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 463 2.1E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 428 2.1E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Pfam PF09078 CheY binding 161 223 2.3E-18 T 10-03-2017 IPR015162 CheY binding RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SMART SM00387 369 509 3.2E-27 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SUPERFAMILY SSF50341 508 640 1.96E-31 T 10-03-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SUPERFAMILY SSF55874 327 507 1.83E-35 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Gene3D G3DSA:1.10.287.560 262 325 3.7E-23 T 10-03-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Pfam PF01627 Hpt domain 8 106 4.7E-20 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 508 8.8E-18 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SUPERFAMILY SSF55052 160 224 1.96E-17 T 10-03-2017 IPR015162 CheY binding RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Gene3D G3DSA:1.20.120.160 3 137 1.8E-43 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Gene3D G3DSA:3.30.70.400 156 227 8.1E-31 T 10-03-2017 IPR015162 CheY binding RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 262 324 1.2E-17 T 10-03-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 SUPERFAMILY SSF47384 262 325 4.71E-15 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Pfam PF01584 CheW-like domain 514 640 4.0E-27 T 10-03-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 RG49_RS00470 01ae4fa258c555b043e33578eb0d8f8c 654 Gene3D G3DSA:3.30.565.10 326 508 2.4E-32 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS17775 6ed557e63f9430a407a0ba7bc8dff3e8 190 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 65 82 - T 10-03-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 RG49_RS17775 6ed557e63f9430a407a0ba7bc8dff3e8 190 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 31 188 2.3E-50 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS17775 6ed557e63f9430a407a0ba7bc8dff3e8 190 SUPERFAMILY SSF50891 26 189 7.01E-59 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS17775 6ed557e63f9430a407a0ba7bc8dff3e8 190 Gene3D G3DSA:2.40.100.10 27 189 3.1E-56 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS17775 6ed557e63f9430a407a0ba7bc8dff3e8 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 59 3.1E-10 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS17775 6ed557e63f9430a407a0ba7bc8dff3e8 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 70 82 3.1E-10 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS17775 6ed557e63f9430a407a0ba7bc8dff3e8 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 144 159 3.1E-10 T 10-03-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 Gene3D G3DSA:2.60.120.10 46 118 1.5E-4 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 Pfam PF12833 Helix-turn-helix domain 191 270 3.4E-21 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 SMART SM00342 185 268 1.4E-30 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 237 252 1.4E-5 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 268 1.4E-5 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 Gene3D G3DSA:1.10.10.60 222 274 9.9E-17 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 222 264 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 Gene3D G3DSA:1.10.10.60 165 221 8.6E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14350 72dc4284e0ec27f04b1861d61bb5e339 283 SUPERFAMILY SSF46689 222 273 2.87E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Gene3D G3DSA:3.40.50.980 79 266 9.0E-46 T 10-03-2017 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 81 2.2E-19 T 10-03-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 SUPERFAMILY SSF56801 11 643 1.57E-192 T 10-03-2017 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Gene3D G3DSA:3.40.50.980 267 424 4.9E-28 T 10-03-2017 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Gene3D G3DSA:3.30.300.30 518 637 6.0E-30 T 10-03-2017 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Pfam PF00501 AMP-binding enzyme 83 522 2.0E-93 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 0.0 T 10-03-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 53.427 T 10-03-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Gene3D G3DSA:2.30.38.10 439 515 1.9E-8 T 10-03-2017 RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 2.7E-26 T 10-03-2017 IPR025110 AMP-binding enzyme C-terminal domain RG49_RS13660 3e6c64958fff1169846d0e965cdd2dfe 652 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 Gene3D G3DSA:2.40.128.130 693 987 2.5E-69 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 SUPERFAMILY SSF103515 695 987 4.05E-55 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 SUPERFAMILY SSF51126 209 688 7.22E-35 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 590 987 3.7E-88 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 Pfam PF03797 Autotransporter beta-domain 725 968 5.5E-45 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 SMART SM00869 726 976 2.9E-43 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 PRINTS PR01484 Pertactin virulence factor family signature 726 746 1.1E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 PRINTS PR01484 Pertactin virulence factor family signature 967 987 1.1E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 PRINTS PR01484 Pertactin virulence factor family signature 942 967 1.1E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 PRINTS PR01484 Pertactin virulence factor family signature 766 790 1.1E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 PRINTS PR01484 Pertactin virulence factor family signature 876 899 1.1E-8 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS09275 8462ebbe0642d207359f8c2274ae7bf2 987 Pfam PF03212 Pertactin 597 679 1.1E-5 T 10-03-2017 IPR004899 Pertactin, central region RG49_RS25265 41d866f9582fe96618beb1d5c4eab673 186 Gene3D G3DSA:3.40.50.10490 11 185 1.2E-36 T 10-03-2017 RG49_RS25265 41d866f9582fe96618beb1d5c4eab673 186 SUPERFAMILY SSF53697 10 185 1.48E-28 T 10-03-2017 RG49_RS25265 41d866f9582fe96618beb1d5c4eab673 186 Pfam PF01380 SIS domain 33 133 9.1E-12 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 297 7.7E-58 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 389 404 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 431 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 185 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 123 132 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 324 345 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.8E-48 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 SUPERFAMILY SSF55424 324 437 1.63E-32 T 10-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 328 434 1.9E-28 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 Gene3D G3DSA:3.50.50.60 128 316 1.2E-49 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PIRSF PIRSF000350 1 438 5.5E-94 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 10-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 SUPERFAMILY SSF51905 1 297 2.94E-51 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 Gene3D G3DSA:3.30.390.30 318 437 4.6E-35 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 2.7E-27 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.7E-27 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 2.7E-27 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 2.7E-27 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 2.7E-27 T 10-03-2017 RG49_RS09665 2458ebb05f095447534c25c58dbdf86c 441 Gene3D G3DSA:3.50.50.60 2 127 1.0E-24 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 SUPERFAMILY SSF56935 34 746 7.79E-140 T 10-03-2017 RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 50 746 7.0E-174 T 10-03-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 Pfam PF00593 TonB dependent receptor 466 744 7.3E-34 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 729 746 - T 10-03-2017 IPR010917 TonB-dependent receptor, conserved site RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 163 8.7E-29 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 41 - T 10-03-2017 IPR010916 TonB box, conserved site RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 Gene3D G3DSA:2.170.130.10 50 165 3.8E-37 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS08220 b2335b0ec8346f3d06b7428cd31e87f5 746 Gene3D G3DSA:2.40.170.20 166 746 8.1E-130 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS09430 ea696720f9aa12cfe5a19758781c1770 393 Gene3D G3DSA:1.20.1250.20 11 185 1.5E-12 T 10-03-2017 RG49_RS09430 ea696720f9aa12cfe5a19758781c1770 393 Pfam PF07690 Major Facilitator Superfamily 27 346 1.3E-23 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS09430 ea696720f9aa12cfe5a19758781c1770 393 Gene3D G3DSA:1.20.1250.20 205 376 4.2E-13 T 10-03-2017 RG49_RS09430 ea696720f9aa12cfe5a19758781c1770 393 TIGRFAM TIGR00896 CynX: cyanate transporter 10 362 8.5E-145 T 10-03-2017 IPR004747 Cyanate transport system protein GO:0016021 RG49_RS09430 ea696720f9aa12cfe5a19758781c1770 393 SUPERFAMILY SSF103473 7 383 6.41E-46 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Hamap MF_00953 DNA topoisomerase 3 [topB]. 1 647 70.955 T 10-03-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 323 332 7.7E-26 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 193 211 7.7E-26 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 402 418 7.7E-26 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 98 111 7.7E-26 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 521 535 7.7E-26 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Gene3D G3DSA:3.40.50.140 1 154 5.7E-47 T 10-03-2017 IPR006171 Toprim domain RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 SMART SM00436 128 223 3.8E-37 T 10-03-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Pfam PF01751 Toprim domain 3 135 1.3E-17 T 10-03-2017 IPR006171 Toprim domain RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 SUPERFAMILY SSF56712 1 607 2.22E-189 T 10-03-2017 IPR023405 DNA topoisomerase, type IA, core domain RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Gene3D G3DSA:1.10.460.10 158 217 5.0E-53 T 10-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Gene3D G3DSA:1.10.460.10 490 607 5.0E-53 T 10-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Gene3D G3DSA:2.70.20.10 369 488 1.5E-49 T 10-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Gene3D G3DSA:2.70.20.10 219 252 1.5E-49 T 10-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 SMART SM00493 1 124 2.9E-31 T 10-03-2017 IPR006171 Toprim domain RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 Pfam PF01131 DNA topoisomerase 158 593 3.1E-114 T 10-03-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 SMART SM00437 280 558 9.6E-110 T 10-03-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 652 0.0 T 10-03-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 RG49_RS01175 9c398b236aac30be7e202dcd1dfd3a2a 653 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 317 332 - T 10-03-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 Gene3D G3DSA:3.30.70.660 115 250 5.4E-47 T 10-03-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 Gene3D G3DSA:3.30.70.580 10 113 1.7E-38 T 10-03-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 SUPERFAMILY SSF55120 9 265 2.59E-93 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 Pfam PF01416 tRNA pseudouridine synthase 17 112 7.4E-10 T 10-03-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 Pfam PF01416 tRNA pseudouridine synthase 151 253 1.8E-28 T 10-03-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 PIRSF PIRSF001430 9 260 1.1E-76 T 10-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 252 35.839 T 10-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS23490 04620e687be86ccefe043fd82f94b73d 270 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 10 247 1.5E-81 T 10-03-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 Gene3D G3DSA:3.40.50.1360 70 210 1.8E-10 T 10-03-2017 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 SMART SM01134 67 228 1.4E-56 T 10-03-2017 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 Pfam PF08220 DeoR-like helix-turn-helix domain 4 59 8.7E-16 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 Pfam PF00455 DeoR C terminal sensor domain 69 227 9.8E-46 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS04140 68c10509da07b1f414db29a661c87670 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 22 36 7.7E-5 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 54 7.7E-5 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 SUPERFAMILY SSF100950 67 229 6.84E-29 T 10-03-2017 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 Gene3D G3DSA:1.10.10.10 2 52 1.7E-9 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04140 68c10509da07b1f414db29a661c87670 249 SMART SM00420 4 56 2.0E-24 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS04140 68c10509da07b1f414db29a661c87670 249 SUPERFAMILY SSF46785 1 60 3.04E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04140 68c10509da07b1f414db29a661c87670 249 ProSitePatterns PS00894 DeoR-type HTH domain signature. 4 38 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 PRINTS PR00988 Uridine kinase signature 87 102 4.1E-39 T 10-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 PRINTS PR00988 Uridine kinase signature 157 168 4.1E-39 T 10-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 PRINTS PR00988 Uridine kinase signature 8 25 4.1E-39 T 10-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 PRINTS PR00988 Uridine kinase signature 143 153 4.1E-39 T 10-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 PRINTS PR00988 Uridine kinase signature 179 192 4.1E-39 T 10-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 PRINTS PR00988 Uridine kinase signature 42 53 4.1E-39 T 10-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 10 199 9.6E-45 T 10-03-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 TIGRFAM TIGR00235 udk: uridine kinase 5 213 1.9E-98 T 10-03-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 SUPERFAMILY SSF52540 8 205 2.58E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 Hamap MF_00551 Uridine kinase [udk]. 5 213 42.04 T 10-03-2017 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 RG49_RS24850 4ed5676e1b1bfa82b39a8a407f81fffd 213 Gene3D G3DSA:3.40.50.300 3 205 6.3E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 SMART SM00342 194 277 7.6E-32 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 Gene3D G3DSA:1.10.10.60 173 231 3.4E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 261 277 4.2E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 246 261 4.2E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 Pfam PF12833 Helix-turn-helix domain 200 278 4.8E-20 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 Gene3D G3DSA:2.60.120.280 8 168 4.4E-51 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 SUPERFAMILY SSF46689 176 227 4.66E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 SUPERFAMILY SSF46689 231 279 2.2E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 Pfam PF02311 AraC-like ligand binding domain 23 160 8.2E-27 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 231 273 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 Gene3D G3DSA:1.10.10.60 232 279 1.0E-16 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11545 83ca0f6b434d115c2d3a74bfc12a9eda 292 SUPERFAMILY SSF51215 8 163 3.66E-39 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 370 395 - T 10-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 360 378 1.2E-32 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 329 343 1.2E-32 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 435 450 1.2E-32 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 135 150 1.2E-32 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 PRINTS PR00132 Glycosyl hydrolase family 2 signature 506 521 1.2E-32 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Gene3D G3DSA:2.60.120.260 2 195 3.0E-72 T 10-03-2017 IPR008979 Galactose-binding domain-like RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 SUPERFAMILY SSF49303 209 318 1.64E-24 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Pfam PF16353 Domain of unknown function(DUF4981) 614 700 6.2E-17 T 10-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Pfam PF02929 Beta galactosidase small chain 730 997 1.2E-64 T 10-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 SUPERFAMILY SSF74650 714 1000 7.53E-85 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 SMART SM01038 727 998 1.6E-124 T 10-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 44 204 1.2E-46 T 10-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Gene3D G3DSA:2.60.40.320 196 318 3.9E-34 T 10-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 SUPERFAMILY SSF49785 1 205 9.07E-61 T 10-03-2017 IPR008979 Galactose-binding domain-like RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Gene3D G3DSA:2.60.40.320 601 701 8.5E-30 T 10-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 320 604 3.3E-120 T 10-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 435 449 - T 10-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Gene3D G3DSA:2.70.98.10 714 1000 2.1E-87 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Gene3D G3DSA:3.20.20.80 320 598 2.5E-91 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 SUPERFAMILY SSF49303 607 705 1.33E-23 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 SUPERFAMILY SSF51445 320 598 4.7E-83 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS19330 695d885ee329a60de897093ae234fd15 1030 Pfam PF00703 Glycosyl hydrolases family 2 209 318 2.1E-19 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS05725 05e09a272b965ca400145d9008ce4b45 230 SMART SM00448 3 113 2.8E-34 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS05725 05e09a272b965ca400145d9008ce4b45 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 1.1E-16 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS05725 05e09a272b965ca400145d9008ce4b45 230 SMART SM00862 153 225 4.8E-18 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS05725 05e09a272b965ca400145d9008ce4b45 230 SUPERFAMILY SSF52172 3 190 5.27E-35 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS05725 05e09a272b965ca400145d9008ce4b45 230 Pfam PF00072 Response regulator receiver domain 5 113 2.5E-27 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS05725 05e09a272b965ca400145d9008ce4b45 230 Gene3D G3DSA:1.10.10.10 129 227 2.7E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS05725 05e09a272b965ca400145d9008ce4b45 230 Gene3D G3DSA:3.40.50.2300 2 128 2.8E-33 T 10-03-2017 RG49_RS00165 34fd35c332193bed9a20befeaaa3a0cd 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 5.6E-30 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS00165 34fd35c332193bed9a20befeaaa3a0cd 89 PIRSF PIRSF004669 1 89 3.7E-33 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS00165 34fd35c332193bed9a20befeaaa3a0cd 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 4.9E-25 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS00165 34fd35c332193bed9a20befeaaa3a0cd 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 4.9E-25 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS00165 34fd35c332193bed9a20befeaaa3a0cd 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 4.9E-25 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS00165 34fd35c332193bed9a20befeaaa3a0cd 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 88 1.5E-34 T 10-03-2017 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 RG49_RS22430 e8b7d7694ac4753e5216a53d66d207fe 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 9.9E-38 T 10-03-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 RG49_RS22430 e8b7d7694ac4753e5216a53d66d207fe 107 Hamap MF_01429 Iron-binding protein IscA [iscA]. 1 107 46.634 T 10-03-2017 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 RG49_RS22430 e8b7d7694ac4753e5216a53d66d207fe 107 SUPERFAMILY SSF89360 1 96 1.01E-32 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS22430 e8b7d7694ac4753e5216a53d66d207fe 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 10-03-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site RG49_RS22430 e8b7d7694ac4753e5216a53d66d207fe 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 3.5E-26 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS22430 e8b7d7694ac4753e5216a53d66d207fe 107 Gene3D G3DSA:2.60.300.12 2 96 7.0E-35 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS22430 e8b7d7694ac4753e5216a53d66d207fe 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 2.6E-62 T 10-03-2017 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 SUPERFAMILY SSF54373 213 314 2.82E-17 T 10-03-2017 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 Pfam PF01266 FAD dependent oxidoreductase 4 352 1.0E-44 T 10-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 Gene3D G3DSA:3.30.9.10 59 146 2.2E-53 T 10-03-2017 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 Gene3D G3DSA:3.30.9.10 212 314 2.2E-53 T 10-03-2017 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 Hamap MF_00515 N-methyl-L-tryptophan oxidase [solA]. 1 372 76.17 T 10-03-2017 IPR023493 N-methyl-L-tryptophan oxidase MTOX GO:0050131|GO:0050660|GO:0055114 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 Gene3D G3DSA:3.50.50.60 147 209 8.2E-57 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 Gene3D G3DSA:3.50.50.60 317 372 8.2E-57 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 Gene3D G3DSA:3.50.50.60 1 57 8.2E-57 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 SUPERFAMILY SSF51905 2 217 2.16E-48 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS05350 d582a80cecd408bcc08972bddd0d1e70 372 SUPERFAMILY SSF51905 314 371 2.16E-48 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15620 78906f2110fea4edf3c146e6eeefdff6 389 Gene3D G3DSA:3.40.50.1820 130 389 2.7E-66 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS15620 78906f2110fea4edf3c146e6eeefdff6 389 Pfam PF00756 Putative esterase 150 309 2.3E-18 T 10-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 RG49_RS15620 78906f2110fea4edf3c146e6eeefdff6 389 Gene3D G3DSA:2.60.40.10 43 102 1.6E-9 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS15620 78906f2110fea4edf3c146e6eeefdff6 389 SUPERFAMILY SSF53474 136 389 3.11E-38 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS15620 78906f2110fea4edf3c146e6eeefdff6 389 SUPERFAMILY SSF81296 45 109 5.95E-10 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS15620 78906f2110fea4edf3c146e6eeefdff6 389 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 43 103 3.4E-8 T 10-03-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 RG49_RS15850 14cc7c3a30d651857f5c0fbe80b7a9e9 120 Pfam PF02656 Domain of unknown function (DUF202) 12 65 5.5E-10 T 10-03-2017 IPR003807 Domain of unknown function DUF202 RG49_RS15850 14cc7c3a30d651857f5c0fbe80b7a9e9 120 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 12 71 1.0E-29 T 10-03-2017 IPR020264 Uncharacterised protein family YidG RG49_RS21205 48a7b796df483692aa64358ff0b142bf 286 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 165 244 6.6E-17 T 10-03-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 RG49_RS21205 48a7b796df483692aa64358ff0b142bf 286 SUPERFAMILY SSF52467 164 279 6.54E-29 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS21205 48a7b796df483692aa64358ff0b142bf 286 Gene3D G3DSA:3.40.50.620 3 152 4.9E-15 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS21205 48a7b796df483692aa64358ff0b142bf 286 Pfam PF01012 Electron transfer flavoprotein domain 41 130 3.2E-6 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS21205 48a7b796df483692aa64358ff0b142bf 286 Gene3D G3DSA:3.40.50.1220 161 282 7.5E-33 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS21205 48a7b796df483692aa64358ff0b142bf 286 PIRSF PIRSF000089 1 286 1.6E-64 T 10-03-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 RG49_RS21205 48a7b796df483692aa64358ff0b142bf 286 SUPERFAMILY SSF52402 4 142 1.53E-9 T 10-03-2017 RG49_RS03450 c46fa3a8e8b8da6113ee7ab3c800f68d 95 Pfam PF06243 Phenylacetic acid degradation B 6 91 3.6E-39 T 10-03-2017 IPR009359 Phenylacetic acid degradation B RG49_RS03450 c46fa3a8e8b8da6113ee7ab3c800f68d 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 95 2.0E-50 T 10-03-2017 IPR009359 Phenylacetic acid degradation B RG49_RS03450 c46fa3a8e8b8da6113ee7ab3c800f68d 95 PIRSF PIRSF030200 1 95 4.7E-44 T 10-03-2017 IPR009359 Phenylacetic acid degradation B RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 Gene3D G3DSA:3.40.50.300 267 490 1.5E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 Gene3D G3DSA:3.40.50.300 2 235 8.7E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 SMART SM00382 277 472 2.6E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 SMART SM00382 29 219 1.7E-6 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 SUPERFAMILY SSF52540 249 483 7.99E-50 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 SUPERFAMILY SSF52540 4 231 1.81E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 Pfam PF00005 ABC transporter 269 423 1.2E-24 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS15465 23707f97023e8f1b82c6afef143a8cb8 501 Pfam PF00005 ABC transporter 22 169 1.2E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 Gene3D G3DSA:3.50.50.60 223 328 2.7E-21 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 SUPERFAMILY SSF51905 217 524 4.62E-50 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 223 513 4.2E-44 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 Gene3D G3DSA:3.40.30.10 115 207 4.6E-35 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 415 431 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 256 271 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 454 475 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 363 387 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 326 334 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 224 246 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 286 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 488 506 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 348 360 1.5E-66 T 10-03-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 Gene3D G3DSA:3.40.30.10 11 104 1.3E-33 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08090 87d7811f474e65999b906214711e49ff 531 Gene3D G3DSA:3.50.50.60 329 520 4.3E-40 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PIRSF PIRSF000238 11 531 5.2E-263 T 10-03-2017 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 11 527 2.2E-240 T 10-03-2017 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 SUPERFAMILY SSF52833 116 207 4.4E-24 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08090 87d7811f474e65999b906214711e49ff 531 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 355 375 - T 10-03-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 Pfam PF13192 Thioredoxin domain 136 205 3.1E-8 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08090 87d7811f474e65999b906214711e49ff 531 SUPERFAMILY SSF52833 11 111 2.68E-29 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 452 468 3.2E-38 T 10-03-2017 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 244 3.2E-38 T 10-03-2017 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 325 343 3.2E-38 T 10-03-2017 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 367 385 3.2E-38 T 10-03-2017 RG49_RS08090 87d7811f474e65999b906214711e49ff 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 478 500 3.2E-38 T 10-03-2017 RG49_RS06235 357aced78900dc6ca3132390a7ae1e35 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.9E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS06235 357aced78900dc6ca3132390a7ae1e35 302 Gene3D G3DSA:1.10.10.10 1 84 7.6E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06235 357aced78900dc6ca3132390a7ae1e35 302 Pfam PF03466 LysR substrate binding domain 91 290 6.6E-34 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS06235 357aced78900dc6ca3132390a7ae1e35 302 SUPERFAMILY SSF46785 1 112 1.4E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06235 357aced78900dc6ca3132390a7ae1e35 302 Gene3D G3DSA:3.40.190.10 179 260 2.2E-19 T 10-03-2017 RG49_RS06235 357aced78900dc6ca3132390a7ae1e35 302 Gene3D G3DSA:3.40.190.10 93 178 2.0E-17 T 10-03-2017 RG49_RS06235 357aced78900dc6ca3132390a7ae1e35 302 SUPERFAMILY SSF53850 91 290 3.88E-36 T 10-03-2017 RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 PIRSF PIRSF000485 1 483 3.6E-173 T 10-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 Gene3D G3DSA:3.40.50.2020 280 446 2.1E-47 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 SUPERFAMILY SSF56235 2 259 7.46E-75 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 SUPERFAMILY SSF53271 252 485 7.08E-72 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 4.3E-163 T 10-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 Gene3D G3DSA:3.60.20.10 2 260 2.2E-64 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 Pfam PF13522 Glutamine amidotransferase domain 64 202 1.8E-15 T 10-03-2017 RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 468 45.099 T 10-03-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 RG49_RS23520 2b1b8f9dfc4399f59f801ef91703255f 505 Pfam PF00156 Phosphoribosyl transferase domain 286 394 1.2E-7 T 10-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 RG49_RS24550 5494622039bb07a07aedb945378bff08 243 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 30 - T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS24550 5494622039bb07a07aedb945378bff08 243 SUPERFAMILY SSF46955 3 90 1.92E-19 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS24550 5494622039bb07a07aedb945378bff08 243 Gene3D G3DSA:1.10.1660.10 4 88 1.1E-19 T 10-03-2017 RG49_RS24550 5494622039bb07a07aedb945378bff08 243 Pfam PF13411 MerR HTH family regulatory protein 4 72 2.3E-18 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS24550 5494622039bb07a07aedb945378bff08 243 SMART SM00422 4 73 5.2E-29 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS22485 1b191014a633b5c1771193980a66d6a7 384 Gene3D G3DSA:3.20.20.70 117 322 9.4E-18 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS22485 1b191014a633b5c1771193980a66d6a7 384 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 364 75.927 T 10-03-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS22485 1b191014a633b5c1771193980a66d6a7 384 PIRSF PIRSF006004 11 378 3.2E-149 T 10-03-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS22485 1b191014a633b5c1771193980a66d6a7 384 Pfam PF04055 Radical SAM superfamily 120 289 2.9E-18 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS22485 1b191014a633b5c1771193980a66d6a7 384 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 13 369 2.4E-179 T 10-03-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS22485 1b191014a633b5c1771193980a66d6a7 384 SUPERFAMILY SSF102114 116 326 4.84E-16 T 10-03-2017 RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 Pfam PF05552 Conserved TM helix 16 64 3.2E-13 T 10-03-2017 IPR008910 Conserved TM helix RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 Gene3D G3DSA:2.30.30.60 129 178 6.0E-20 T 10-03-2017 RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 SUPERFAMILY SSF82861 28 112 7.98E-18 T 10-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 SUPERFAMILY SSF82689 181 278 2.48E-33 T 10-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 143 177 - T 10-03-2017 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 Gene3D G3DSA:3.30.70.100 182 266 1.6E-32 T 10-03-2017 RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 SUPERFAMILY SSF50182 114 179 6.87E-17 T 10-03-2017 IPR010920 LSM domain RG49_RS20270 3f5066a57f5874d23b5e7683e1774555 286 Pfam PF00924 Mechanosensitive ion channel 72 268 7.3E-59 T 10-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 Gene3D G3DSA:3.30.43.10 17 109 1.8E-26 T 10-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 Pfam PF01565 FAD binding domain 56 194 3.6E-35 T 10-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 SUPERFAMILY SSF55103 204 474 8.01E-78 T 10-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 SUPERFAMILY SSF56176 21 231 7.94E-65 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 Gene3D G3DSA:3.30.465.10 111 231 8.1E-32 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 59 470 8.6E-192 T 10-03-2017 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 Pfam PF02913 FAD linked oxidases, C-terminal domain 230 470 4.3E-69 T 10-03-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 RG49_RS19900 89bb9b613b675dd2f4cc12cbb2dd3c21 499 Gene3D G3DSA:1.10.45.10 432 471 2.8E-9 T 10-03-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 605 619 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 6.2E-88 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82693 788 833 2.62E-6 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82693 662 701 2.62E-6 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Hamap MF_01424 Multidrug resistance protein MdtC [mdtC]. 1 1024 27.133 T 10-03-2017 IPR023931 Multidrug resistance protein MdtC RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Gene3D G3DSA:3.30.70.1430 40 142 4.7E-30 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82866 291 490 7.19E-49 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Gene3D G3DSA:1.20.1640.10 285 500 9.5E-59 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Gene3D G3DSA:3.30.70.1430 557 649 9.0E-14 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82693 555 650 1.4E-18 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82714 183 266 5.1E-16 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82693 40 135 4.19E-23 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Pfam PF00873 AcrB/AcrD/AcrF family 4 1008 0.0 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82693 136 182 4.71E-23 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82693 268 324 4.71E-23 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82714 703 785 4.32E-16 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Gene3D G3DSA:1.10.3850.10 794 1010 6.6E-54 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 SUPERFAMILY SSF82866 813 1010 2.75E-43 T 10-03-2017 RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Gene3D G3DSA:3.30.2090.10 183 264 6.2E-16 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS24795 95dac64c18ce9a846eda1f7c7f30290f 1025 Gene3D G3DSA:3.30.2090.10 703 784 2.5E-16 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS16740 066f7bd100a8dcf0ad4f7e37517c0e12 187 SUPERFAMILY SSF48150 2 184 1.44E-82 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS16740 066f7bd100a8dcf0ad4f7e37517c0e12 187 Gene3D G3DSA:1.10.340.30 1 182 1.6E-88 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS16740 066f7bd100a8dcf0ad4f7e37517c0e12 187 Pfam PF03352 Methyladenine glycosylase 6 181 3.4E-82 T 10-03-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 RG49_RS16740 066f7bd100a8dcf0ad4f7e37517c0e12 187 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 2 182 4.2E-98 T 10-03-2017 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 Gene3D G3DSA:3.50.50.60 279 338 4.6E-57 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 Gene3D G3DSA:3.50.50.60 5 150 4.6E-57 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PIRSF PIRSF000350 2 463 6.6E-70 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 2 466 70.383 T 10-03-2017 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 SUPERFAMILY SSF55424 345 463 1.05E-30 T 10-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 SUPERFAMILY SSF51905 2 335 2.75E-54 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 Gene3D G3DSA:3.50.50.60 157 278 1.7E-25 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 457 1.7E-30 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 9.4E-25 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 9.4E-25 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 9.4E-25 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 9.4E-25 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 9.4E-25 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 3.4E-58 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 1.1E-49 T 10-03-2017 RG49_RS14300 b41e72a4c433caa23623d4acc83b24c6 466 Gene3D G3DSA:3.30.390.30 345 460 2.7E-33 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 Gene3D G3DSA:3.40.50.720 2 202 5.5E-38 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 123 1.5E-27 T 10-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 SUPERFAMILY SSF48179 204 381 5.1E-47 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 150 162 - T 10-03-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 SUPERFAMILY SSF51735 1 203 3.94E-44 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 Gene3D G3DSA:1.10.1040.10 203 381 8.2E-51 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 9.8E-18 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 PRINTS PR00084 Mannitol dehydrogenase signature 114 127 9.8E-18 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 PRINTS PR00084 Mannitol dehydrogenase signature 170 185 9.8E-18 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 PRINTS PR00084 Mannitol dehydrogenase signature 150 163 9.8E-18 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 148 373 2.9E-69 T 10-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 RG49_RS16425 cfdeb37c3d284715001c9b2225291cda 382 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 378 42.195 T 10-03-2017 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS16475 d18afbf78dee68b5e81f6540cfe98193 280 Pfam PF13646 HEAT repeats 138 183 8.9E-7 T 10-03-2017 RG49_RS16475 d18afbf78dee68b5e81f6540cfe98193 280 SUPERFAMILY SSF48371 26 276 2.84E-43 T 10-03-2017 IPR016024 Armadillo-type fold GO:0005488 RG49_RS16475 d18afbf78dee68b5e81f6540cfe98193 280 Gene3D G3DSA:1.25.10.10 8 279 2.5E-48 T 10-03-2017 IPR011989 Armadillo-like helical RG49_RS19815 676d35389c27f40daf8cdec20faf357b 288 SUPERFAMILY SSF47616 133 279 1.17E-32 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS19815 676d35389c27f40daf8cdec20faf357b 288 Gene3D G3DSA:1.20.1050.10 131 254 1.3E-43 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS19815 676d35389c27f40daf8cdec20faf357b 288 Pfam PF13410 Glutathione S-transferase, C-terminal domain 175 244 2.2E-9 T 10-03-2017 RG49_RS19815 676d35389c27f40daf8cdec20faf357b 288 Pfam PF02798 Glutathione S-transferase, N-terminal domain 65 127 6.2E-6 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS19815 676d35389c27f40daf8cdec20faf357b 288 Gene3D G3DSA:3.40.30.10 33 130 4.5E-27 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS19815 676d35389c27f40daf8cdec20faf357b 288 SUPERFAMILY SSF52833 37 130 6.34E-17 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS09020 0f0feee8b183ef8c8fdd4ac0df27ae16 80 Gene3D G3DSA:1.10.287.1040 6 78 8.8E-31 T 10-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS09020 0f0feee8b183ef8c8fdd4ac0df27ae16 80 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 50 1.0E-21 T 10-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS09020 0f0feee8b183ef8c8fdd4ac0df27ae16 80 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 65 1.2E-24 T 10-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS09020 0f0feee8b183ef8c8fdd4ac0df27ae16 80 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 17.147 T 10-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS09020 0f0feee8b183ef8c8fdd4ac0df27ae16 80 Pfam PF02609 Exonuclease VII small subunit 11 62 6.4E-22 T 10-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS09020 0f0feee8b183ef8c8fdd4ac0df27ae16 80 PIRSF PIRSF006488 1 80 8.9E-25 T 10-03-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS09020 0f0feee8b183ef8c8fdd4ac0df27ae16 80 SUPERFAMILY SSF116842 3 73 4.45E-23 T 10-03-2017 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 Gene3D G3DSA:3.90.700.10 234 352 3.6E-37 T 10-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 SUPERFAMILY SSF56425 227 358 6.88E-43 T 10-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 Gene3D G3DSA:3.50.50.60 353 414 1.2E-105 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 Gene3D G3DSA:3.50.50.60 3 233 1.2E-105 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 Pfam PF02910 Fumarate reductase flavoprotein C-term 453 581 1.0E-38 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 3.0E-10 T 10-03-2017 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.0E-10 T 10-03-2017 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 2.5E-5 T 10-03-2017 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.5E-5 T 10-03-2017 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 581 1.1E-249 T 10-03-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 Gene3D G3DSA:1.20.58.100 426 537 1.5E-38 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 SUPERFAMILY SSF46977 444 590 3.01E-46 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 TIGRFAM TIGR01176 fum_red_Fp: fumarate reductase (quinol), flavoprotein subunit 3 582 0.0 T 10-03-2017 IPR005884 Fumarate reductase, flavoprotein subunit GO:0009061|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.4|KEGG: 00620+1.3.5.4|KEGG: 00650+1.3.5.4|KEGG: 00720+1.3.5.4|MetaCyc: PWY-5392|MetaCyc: PWY-5913|MetaCyc: PWY-7384 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 10-03-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 SUPERFAMILY SSF51905 361 413 3.21E-71 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 SUPERFAMILY SSF51905 3 250 3.21E-71 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 PIRSF PIRSF000171 1 576 3.4E-42 T 10-03-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 Pfam PF00890 FAD binding domain 7 397 1.3E-115 T 10-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13145 067b000d179bbe8944002d534fdead97 602 Gene3D G3DSA:4.10.80.40 543 577 5.5E-18 T 10-03-2017 RG49_RS12070 62a2315caad4ac4510e60596a8c2502e 137 TIGRFAM TIGR00664 DNA_III_psi: DNA polymerase III, psi subunit 1 125 4.1E-62 T 10-03-2017 IPR018382 DNA polymerase III, psi subunit, subgroup GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS12070 62a2315caad4ac4510e60596a8c2502e 137 SUPERFAMILY SSF102220 27 135 1.83E-34 T 10-03-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS12070 62a2315caad4ac4510e60596a8c2502e 137 ProDom PD032475 DNA POLYMERASE PSI SUBUNIT III TRANSFERASE NUCLEOTIDYLTRANSFERASE III 3D-STRUCTURE DNA-DIRECTED 34 125 1.0E-45 T 10-03-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS12070 62a2315caad4ac4510e60596a8c2502e 137 Gene3D G3DSA:3.40.50.10220 26 136 7.5E-45 T 10-03-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS12070 62a2315caad4ac4510e60596a8c2502e 137 Pfam PF03603 DNA polymerase III psi subunit 3 127 4.3E-44 T 10-03-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS12070 62a2315caad4ac4510e60596a8c2502e 137 PIRSF PIRSF029225 2 131 1.5E-49 T 10-03-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 Gene3D G3DSA:1.10.10.10 10 64 5.4E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 Pfam PF08220 DeoR-like helix-turn-helix domain 18 74 6.5E-21 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 ProSitePatterns PS00894 DeoR-type HTH domain signature. 18 52 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 SUPERFAMILY SSF46785 16 71 9.31E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 Pfam PF00455 DeoR C terminal sensor domain 89 247 3.5E-56 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 SMART SM00420 18 70 9.2E-22 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 SMART SM01134 87 248 6.7E-71 T 10-03-2017 RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 SUPERFAMILY SSF100950 89 249 8.37E-33 T 10-03-2017 RG49_RS19015 ee2d2e7a80323569820151d9dbb37af8 269 Gene3D G3DSA:3.40.50.1360 90 231 9.6E-17 T 10-03-2017 RG49_RS11375 bf027aecde1ae723b927b94a26fa4936 305 SUPERFAMILY SSF54211 134 278 3.34E-54 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS11375 bf027aecde1ae723b927b94a26fa4936 305 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 301 2.6E-164 T 10-03-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS11375 bf027aecde1ae723b927b94a26fa4936 305 SUPERFAMILY SSF54211 3 124 1.29E-41 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS11375 bf027aecde1ae723b927b94a26fa4936 305 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 280 46.002 T 10-03-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS11375 bf027aecde1ae723b927b94a26fa4936 305 Gene3D G3DSA:3.30.1700.10 129 283 3.0E-63 T 10-03-2017 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS11375 bf027aecde1ae723b927b94a26fa4936 305 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 276 8.1E-109 T 10-03-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS11375 bf027aecde1ae723b927b94a26fa4936 305 Gene3D G3DSA:3.30.230.20 3 124 1.7E-45 T 10-03-2017 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 Pfam PF02863 Arginine repressor, C-terminal domain 82 148 8.6E-23 T 10-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 SUPERFAMILY SSF46785 3 77 1.81E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 PRINTS PR01467 Bacterial arginine repressor signature 25 38 1.3E-24 T 10-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 PRINTS PR01467 Bacterial arginine repressor signature 42 57 1.3E-24 T 10-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 PRINTS PR01467 Bacterial arginine repressor signature 121 136 1.3E-24 T 10-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 PRINTS PR01467 Bacterial arginine repressor signature 90 103 1.3E-24 T 10-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 Gene3D G3DSA:3.30.1360.40 80 154 2.2E-27 T 10-03-2017 IPR024946 Arginine repressor C-terminal-like domain RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 TIGRFAM TIGR01529 argR_whole: arginine repressor 9 152 3.2E-49 T 10-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 Pfam PF01316 Arginine repressor, DNA binding domain 5 74 1.8E-26 T 10-03-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 SUPERFAMILY SSF55252 82 151 1.05E-19 T 10-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 Hamap MF_00173 Arginine repressor [argR]. 1 155 61.063 T 10-03-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 Gene3D G3DSA:1.10.10.10 2 77 1.9E-35 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS18435 91d0535ec00ce932aac0c98e8a6bf9df 156 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 153 3.0E-31 T 10-03-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 RG49_RS14585 57c7edb2dfd0b70ab767a6a057f85cd5 224 SUPERFAMILY SSF50800 3 223 1.1E-75 T 10-03-2017 IPR011037 Pyruvate kinase-like, insert domain RG49_RS14585 57c7edb2dfd0b70ab767a6a057f85cd5 224 Gene3D G3DSA:2.40.33.20 4 223 2.7E-87 T 10-03-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like RG49_RS14585 57c7edb2dfd0b70ab767a6a057f85cd5 224 Pfam PF03475 3-alpha domain 169 211 1.5E-14 T 10-03-2017 IPR005163 3-alpha domain RG49_RS14585 57c7edb2dfd0b70ab767a6a057f85cd5 224 Pfam PF03473 MOSC domain 47 159 1.5E-19 T 10-03-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Pfam PF09334 tRNA synthetases class I (M) 8 397 3.6E-165 T 10-03-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 SUPERFAMILY SSF57770 142 176 1.15E-12 T 10-03-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 536 6.6E-210 T 10-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Gene3D G3DSA:2.20.28.20 145 176 1.5E-19 T 10-03-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 546 41.906 T 10-03-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 SUPERFAMILY SSF52374 176 388 1.13E-106 T 10-03-2017 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 SUPERFAMILY SSF52374 6 141 1.13E-106 T 10-03-2017 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Pfam PF01588 Putative tRNA binding domain 581 674 4.9E-22 T 10-03-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 543 677 1.8E-48 T 10-03-2017 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Gene3D G3DSA:3.40.50.620 183 385 2.0E-93 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Gene3D G3DSA:3.40.50.620 6 144 2.0E-93 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 SUPERFAMILY SSF50249 570 676 1.64E-28 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Gene3D G3DSA:1.10.730.10 391 526 2.2E-42 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 SUPERFAMILY SSF47323 391 548 1.25E-46 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 Gene3D G3DSA:2.40.50.140 568 677 9.8E-39 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 292 307 5.8E-26 T 10-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 5.8E-26 T 10-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 5.8E-26 T 10-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 5.8E-26 T 10-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 5.8E-26 T 10-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS24610 da7e0901e1283c067b269c7d371b992b 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 385 396 5.8E-26 T 10-03-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 SUPERFAMILY SSF46946 126 214 1.44E-17 T 10-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 Gene3D G3DSA:1.10.8.50 127 263 7.8E-33 T 10-03-2017 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 Hamap MF_01253 Endonuclease 8 [nei]. 1 263 68.103 T 10-03-2017 IPR023713 Endonuclease VIII GO:0003684|GO:0004519|GO:0006284|GO:0008270 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 104 1.7E-11 T 10-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 Pfam PF06827 Zinc finger found in FPG and IleRS 235 263 1.7E-8 T 10-03-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 SUPERFAMILY SSF81624 2 127 3.53E-27 T 10-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 ProSitePatterns PS01242 Zinc finger FPG-type signature. 238 262 - T 10-03-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 127 205 1.4E-10 T 10-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 SUPERFAMILY SSF57716 226 262 5.17E-11 T 10-03-2017 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 SMART SM00898 2 110 9.7E-15 T 10-03-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 Gene3D G3DSA:3.20.190.10 2 105 1.1E-17 T 10-03-2017 RG49_RS07520 0e534de03044ef21a19a0dd725a64b6a 263 SMART SM01232 126 221 2.4E-16 T 10-03-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 RG49_RS16440 139fc176d0f5ba99233b005d9e43b246 378 Gene3D G3DSA:2.40.50.100 65 96 6.4E-14 T 10-03-2017 RG49_RS16440 139fc176d0f5ba99233b005d9e43b246 378 Gene3D G3DSA:2.40.50.100 219 243 6.4E-14 T 10-03-2017 RG49_RS16440 139fc176d0f5ba99233b005d9e43b246 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 301 1.9E-9 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS16440 139fc176d0f5ba99233b005d9e43b246 378 SUPERFAMILY SSF111369 198 267 2.09E-13 T 10-03-2017 RG49_RS16440 139fc176d0f5ba99233b005d9e43b246 378 SUPERFAMILY SSF111369 60 118 2.09E-13 T 10-03-2017 RG49_RS16440 139fc176d0f5ba99233b005d9e43b246 378 Pfam PF00529 HlyD membrane-fusion protein of T1SS 13 367 1.9E-13 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS09175 2803dfeb0ae7ed649845703d52f5fbb8 94 Pfam PF06865 Protein of unknown function (DUF1255) 3 93 1.2E-33 T 10-03-2017 IPR009664 Protein of unknown function DUF1255 RG49_RS09175 2803dfeb0ae7ed649845703d52f5fbb8 94 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 1 94 25.868 T 10-03-2017 IPR009664 Protein of unknown function DUF1255 RG49_RS09175 2803dfeb0ae7ed649845703d52f5fbb8 94 SUPERFAMILY SSF51182 1 94 6.85E-33 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS09175 2803dfeb0ae7ed649845703d52f5fbb8 94 Gene3D G3DSA:2.60.120.10 1 94 1.5E-37 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Pfam PF00563 EAL domain 896 1088 1.7E-20 T 10-03-2017 IPR001633 EAL domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Gene3D G3DSA:3.30.70.270 684 847 9.1E-52 T 10-03-2017 RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Pfam PF05231 MASE1 19 294 2.6E-34 T 10-03-2017 IPR007895 MASE1 RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00052 855 1095 2.4E-51 T 10-03-2017 IPR001633 EAL domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SUPERFAMILY SSF55073 687 845 2.12E-46 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Gene3D G3DSA:3.30.450.20 437 541 8.3E-16 T 10-03-2017 RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00086 629 671 0.021 T 10-03-2017 IPR001610 PAC motif RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00086 502 543 1.8E-5 T 10-03-2017 IPR001610 PAC motif RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00086 375 417 3.6E-9 T 10-03-2017 IPR001610 PAC motif RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Gene3D G3DSA:3.30.450.20 542 669 8.4E-18 T 10-03-2017 RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Pfam PF08447 PAS fold 452 537 8.7E-10 T 10-03-2017 IPR013655 PAS fold-3 GO:0005515 RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SUPERFAMILY SSF55785 438 545 1.15E-14 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 553 676 5.4E-13 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 299 422 1.9E-35 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SUPERFAMILY SSF55785 541 669 5.32E-19 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SUPERFAMILY SSF141868 899 1096 2.09E-18 T 10-03-2017 IPR001633 EAL domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Pfam PF00990 Diguanylate cyclase, GGDEF domain 682 838 1.9E-45 T 10-03-2017 IPR000160 GGDEF domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SUPERFAMILY SSF55785 309 419 7.73E-22 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00267 671 843 3.5E-67 T 10-03-2017 IPR000160 GGDEF domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Pfam PF13426 PAS domain 314 416 2.0E-11 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Gene3D G3DSA:3.20.20.450 900 1095 1.2E-22 T 10-03-2017 IPR001633 EAL domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00091 555 623 5.0E-8 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00091 302 368 2.1E-11 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 SMART SM00091 429 496 0.35 T 10-03-2017 IPR000014 PAS domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 680 842 1.7E-37 T 10-03-2017 IPR000160 GGDEF domain RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Gene3D G3DSA:3.30.450.20 300 436 3.8E-23 T 10-03-2017 RG49_RS24845 40b4eda7b2f47553c6a1291968c00527 1105 Pfam PF08448 PAS fold 561 672 2.3E-10 T 10-03-2017 IPR013656 PAS fold-4 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 ProSitePatterns PS00480 Citrate synthase signature. 303 315 - T 10-03-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 Pfam PF00285 Citrate synthase, C-terminal domain 46 410 6.7E-132 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 PIRSF PIRSF001369 38 427 2.8E-177 T 10-03-2017 IPR024176 Citrate synthase, bacterial-type RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 Gene3D G3DSA:1.10.580.10 52 280 2.1E-95 T 10-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 421 2.8E-244 T 10-03-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 SUPERFAMILY SSF48256 9 423 4.97E-168 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 Gene3D G3DSA:1.10.230.10 281 373 3.7E-43 T 10-03-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 PRINTS PR00143 Citrate synthase signature 165 178 5.1E-56 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 PRINTS PR00143 Citrate synthase signature 359 375 5.1E-56 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 PRINTS PR00143 Citrate synthase signature 219 234 5.1E-56 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 PRINTS PR00143 Citrate synthase signature 241 269 5.1E-56 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 PRINTS PR00143 Citrate synthase signature 379 393 5.1E-56 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS07470 80831e5897dcdbfa195d6398bb4b3eea 427 PRINTS PR00143 Citrate synthase signature 296 316 5.1E-56 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 628 47.258 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 SUPERFAMILY SSF55874 5 215 9.75E-70 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 SMART SM00387 27 173 2.4E-19 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 31 46 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 517 529 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 66 79 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 560 576 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 414 428 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 497 514 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 109 123 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 266 279 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR00418 DNA topoisomerase II family signature 479 495 1.1E-58 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Pfam PF01751 Toprim domain 413 521 1.8E-12 T 10-03-2017 IPR006171 Toprim domain RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 SMART SM00433 34 624 2.8E-213 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 625 0.0 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Pfam PF00204 DNA gyrase B 218 384 4.7E-39 T 10-03-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 ProSitePatterns PS00177 DNA topoisomerase II signature. 416 424 - T 10-03-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Gene3D G3DSA:3.30.230.10 217 390 3.4E-47 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 537 559 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 294 310 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 362 387 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 338 361 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 503 519 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 448 469 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 469 481 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 PRINTS PR01098 Topoisomerase IV subunit B signature 311 326 2.0E-159 T 10-03-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 SUPERFAMILY SSF56719 388 621 3.4E-78 T 10-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Gene3D G3DSA:3.40.50.670 398 611 3.9E-77 T 10-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 171 3.6E-18 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Gene3D G3DSA:3.30.565.10 15 215 6.2E-78 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 SUPERFAMILY SSF54211 217 382 2.85E-47 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS19600 f5687ae93ae586f4f9ea80ed1c23a9e2 630 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 556 620 2.4E-25 T 10-03-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS21920 b8e19317c80d1feb35591566447045f4 395 Gene3D G3DSA:1.10.150.130 107 204 3.0E-15 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS21920 b8e19317c80d1feb35591566447045f4 395 Pfam PF13356 Domain of unknown function (DUF4102) 8 93 2.1E-15 T 10-03-2017 IPR025166 Domain of unknown function DUF4102 RG49_RS21920 b8e19317c80d1feb35591566447045f4 395 Gene3D G3DSA:1.10.443.10 214 384 1.4E-25 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS21920 b8e19317c80d1feb35591566447045f4 395 Pfam PF00589 Phage integrase family 213 377 8.0E-28 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS21920 b8e19317c80d1feb35591566447045f4 395 SUPERFAMILY SSF56349 107 387 1.32E-58 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS22335 967d551a0a95673af4c12948871ee910 503 Pfam PF00005 ABC transporter 278 432 1.7E-23 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS22335 967d551a0a95673af4c12948871ee910 503 Pfam PF00005 ABC transporter 26 178 3.0E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS22335 967d551a0a95673af4c12948871ee910 503 SUPERFAMILY SSF52540 17 229 5.43E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22335 967d551a0a95673af4c12948871ee910 503 Gene3D G3DSA:3.40.50.300 17 234 2.9E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22335 967d551a0a95673af4c12948871ee910 503 Gene3D G3DSA:3.40.50.300 273 485 1.3E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22335 967d551a0a95673af4c12948871ee910 503 SUPERFAMILY SSF52540 273 483 5.75E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22335 967d551a0a95673af4c12948871ee910 503 SMART SM00382 287 480 3.6E-6 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS22335 967d551a0a95673af4c12948871ee910 503 SMART SM00382 35 226 2.9E-6 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS22335 967d551a0a95673af4c12948871ee910 503 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 Gene3D G3DSA:3.30.70.20 191 279 1.2E-16 T 10-03-2017 RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 TIGRFAM TIGR02163 napH_: ferredoxin-type protein, NapH/MauN family 24 278 4.7E-117 T 10-03-2017 IPR011886 Ferredoxin-type protein, NapH/MauN family GO:0005506 RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 SUPERFAMILY SSF54862 191 280 6.98E-21 T 10-03-2017 RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 SUPERFAMILY SSF54862 103 143 6.98E-21 T 10-03-2017 RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 226 237 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 Pfam PF12801 4Fe-4S binding domain 83 126 1.4E-12 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 Pfam PF12801 4Fe-4S binding domain 178 211 7.2E-5 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24120 c0e1253dde259199d4f90ddcf37db47d 287 Pfam PF13237 4Fe-4S dicluster domain 221 270 6.1E-7 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS22450 e4776e4a90b74421af46968294e1b9ec 66 Pfam PF04384 Iron-sulphur cluster assembly 3 66 3.1E-32 T 10-03-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 RG49_RS22450 e4776e4a90b74421af46968294e1b9ec 66 PIRSF PIRSF039003 3 66 3.2E-33 T 10-03-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 RG49_RS22450 e4776e4a90b74421af46968294e1b9ec 66 Gene3D G3DSA:1.10.10.600 1 66 6.3E-35 T 10-03-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 RG49_RS22450 e4776e4a90b74421af46968294e1b9ec 66 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 4 66 9.9E-33 T 10-03-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 RG49_RS22450 e4776e4a90b74421af46968294e1b9ec 66 SUPERFAMILY SSF140319 3 64 3.79E-27 T 10-03-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 RG49_RS20295 0e95d9058728eda4dbe930caf65005d8 261 Gene3D G3DSA:3.90.226.10 2 200 3.0E-47 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS20295 0e95d9058728eda4dbe930caf65005d8 261 SUPERFAMILY SSF52096 1 260 6.01E-62 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS20295 0e95d9058728eda4dbe930caf65005d8 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 10-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 RG49_RS20295 0e95d9058728eda4dbe930caf65005d8 261 Gene3D G3DSA:1.10.12.10 203 260 2.6E-17 T 10-03-2017 IPR014748 Crontonase, C-terminal RG49_RS20295 0e95d9058728eda4dbe930caf65005d8 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 259 5.5E-47 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS03165 8de8badeaf39e2e16977a0c02fb92745 77 Pfam PF10735 Protein of unknown function (DUF2526) 1 77 5.5E-44 T 10-03-2017 IPR019671 Protein of unknown function DUF2526 RG49_RS10555 a4fdd8c0939bdd567d3feb8ccc8b86db 92 TIGRFAM TIGR00053 TIGR00053: addiction module toxin component, YafQ family 4 91 1.1E-35 T 10-03-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin RG49_RS10555 a4fdd8c0939bdd567d3feb8ccc8b86db 92 SUPERFAMILY SSF143011 4 91 6.28E-23 T 10-03-2017 RG49_RS10555 a4fdd8c0939bdd567d3feb8ccc8b86db 92 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 6 91 4.8E-26 T 10-03-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family RG49_RS10555 a4fdd8c0939bdd567d3feb8ccc8b86db 92 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 5 92 3.2E-31 T 10-03-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin RG49_RS10555 a4fdd8c0939bdd567d3feb8ccc8b86db 92 PIRSF PIRSF006156 3 92 3.5E-23 T 10-03-2017 IPR004386 Toxin-antitoxin system, YafQ-like toxin RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 ProSitePatterns PS00538 Bacterial chemotaxis sensory transducers signature. 290 312 - T 10-03-2017 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 511 8.8E-62 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 SMART SM00304 212 264 5.7E-9 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 SUPERFAMILY SSF47170 39 176 1.31E-36 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 Pfam PF00672 HAMP domain 195 260 1.4E-9 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 SUPERFAMILY SSF58104 232 513 7.85E-74 T 10-03-2017 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 Pfam PF02203 Tar ligand binding domain homologue 1 168 2.1E-44 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 SMART SM00319 44 178 2.2E-56 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 Gene3D G3DSA:1.20.120.30 36 176 8.6E-38 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 SMART SM00283 265 512 1.1E-91 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 3.8E-79 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 188 208 3.8E-79 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 3.8E-79 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 3.8E-79 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 3.8E-79 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 3.8E-79 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 53 68 3.8E-79 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00485 45e286554e3df152f56813118e2fe79a 533 Gene3D G3DSA:1.10.287.950 281 484 6.4E-62 T 10-03-2017 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 8 27 8.4E-67 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 164 185 8.4E-67 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 27 47 8.4E-67 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 47 66 8.4E-67 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 143 163 8.4E-67 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 188 213 8.4E-67 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 Pfam PF00813 FliP family 10 210 3.3E-61 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 191 203 - T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS20635 8b6fb83347d5ec86cb8ebe96971f836c 221 TIGRFAM TIGR01102 yscR: type III secretion apparatus protein, YscR/HrcR family 7 210 3.3E-77 T 10-03-2017 IPR005773 Yop virulence translocation protein R GO:0015031|GO:0016021 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 10-03-2017 IPR025505 FHIPEP conserved site RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 5.9E-57 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 5.9E-57 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 5.9E-57 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 5.9E-57 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 5.9E-57 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 5.9E-57 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 22 689 9.6E-286 T 10-03-2017 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 PIRSF PIRSF005419 9 692 3.6E-243 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS00515 0fd1f6590ec3ce8425fa67ed9122a3ba 692 Pfam PF00771 FHIPEP family 31 680 1.7E-269 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS14735 e0597917e9d119cfd9f41705c45f3e94 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.4E-77 T 10-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 RG49_RS14735 e0597917e9d119cfd9f41705c45f3e94 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 143 7.6E-54 T 10-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 RG49_RS14735 e0597917e9d119cfd9f41705c45f3e94 145 SUPERFAMILY SSF69500 1 144 4.05E-57 T 10-03-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain RG49_RS14735 e0597917e9d119cfd9f41705c45f3e94 145 Gene3D G3DSA:3.50.80.10 1 144 1.8E-57 T 10-03-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain RG49_RS14735 e0597917e9d119cfd9f41705c45f3e94 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 35.328 T 10-03-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 Gene3D G3DSA:3.40.50.720 1 143 1.1E-74 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 131 284 1.1E-61 T 10-03-2017 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 SUPERFAMILY SSF55347 131 284 2.81E-65 T 10-03-2017 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 3 308 1.9E-139 T 10-03-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 PIRSF PIRSF015689 1 315 3.6E-132 T 10-03-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 316 144.663 T 10-03-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 SMART SM00859 5 123 7.4E-14 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 118 7.5E-12 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 SUPERFAMILY SSF51735 1 155 1.26E-28 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09935 5cd78ba53d143da2c86f0f5e8f29016a 316 Gene3D G3DSA:3.30.360.10 144 284 5.7E-73 T 10-03-2017 RG49_RS10275 d5e1c254f40924f5dee5865ff757aaf2 136 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 20 117 3.7E-8 T 10-03-2017 IPR008767 Bacteriophage SPP1, head-tail adaptor RG49_RS10275 d5e1c254f40924f5dee5865ff757aaf2 136 Pfam PF05521 Phage head-tail joining protein 21 115 8.2E-17 T 10-03-2017 IPR008767 Bacteriophage SPP1, head-tail adaptor RG49_RS08455 89094bac9fe35ef8f5c399b216e1173a 240 SUPERFAMILY SSF56300 4 239 2.93E-31 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS08455 89094bac9fe35ef8f5c399b216e1173a 240 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 240 133.123 T 10-03-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 RG49_RS08455 89094bac9fe35ef8f5c399b216e1173a 240 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 203 1.4E-9 T 10-03-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 RG49_RS08455 89094bac9fe35ef8f5c399b216e1173a 240 Gene3D G3DSA:3.60.21.10 3 125 2.6E-22 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS08455 89094bac9fe35ef8f5c399b216e1173a 240 Gene3D G3DSA:3.60.21.10 173 218 2.6E-22 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS08455 89094bac9fe35ef8f5c399b216e1173a 240 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 232 1.7E-117 T 10-03-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 PIRSF PIRSF000876 1 346 3.1E-137 T 10-03-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 Pfam PF00072 Response regulator receiver domain 6 109 8.2E-25 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 SMART SM00448 4 119 8.4E-22 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 SUPERFAMILY SSF52738 156 342 8.11E-75 T 10-03-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 Gene3D G3DSA:3.40.50.180 155 341 5.1E-84 T 10-03-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 Gene3D G3DSA:3.40.50.2300 2 108 6.6E-28 T 10-03-2017 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 Pfam PF01339 CheB methylesterase 159 336 4.7E-62 T 10-03-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 SUPERFAMILY SSF52172 1 108 1.07E-27 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS00495 d7ca2da6916071214a13bfe112701d72 349 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 342 41.365 T 10-03-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 RG49_RS11145 7373ede3a4d3b4c68900631cd3749d12 436 Pfam PF00577 Outer membrane usher protein 4 342 1.8E-67 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS11145 7373ede3a4d3b4c68900631cd3749d12 436 Pfam PF13953 PapC C-terminal domain 351 414 1.7E-18 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 1.4E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 1.4E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 1.4E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 1.4E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 SUPERFAMILY SSF56784 6 217 1.79E-47 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 Gene3D G3DSA:3.40.50.1000 10 195 1.1E-28 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 13 191 1.3E-19 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17590 50de4a9acc2a2c50cf28b01e4ddd6a12 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 190 1.3E-10 T 10-03-2017 IPR023214 HAD-like domain RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 Pfam PF01743 Poly A polymerase head domain 3 122 1.1E-18 T 10-03-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 Gene3D G3DSA:1.10.3090.10 122 359 1.6E-57 T 10-03-2017 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 PIRSF PIRSF000813 1 408 2.6E-209 T 10-03-2017 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 4.5E-16 T 10-03-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 SUPERFAMILY SSF81891 120 402 1.27E-55 T 10-03-2017 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 Pfam PF01966 HD domain 229 328 3.1E-12 T 10-03-2017 IPR006674 HD domain RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 Hamap MF_01262 CCA-adding enzyme [cca]. 1 401 47.105 T 10-03-2017 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 407 54.86 T 10-03-2017 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 Gene3D G3DSA:3.30.460.10 2 121 1.3E-31 T 10-03-2017 RG49_RS19460 53249fd3fc6cf7259d4b4ddad777ec37 412 SUPERFAMILY SSF81301 2 119 2.4E-32 T 10-03-2017 RG49_RS01795 63968336180e46a7b732b33ba7812b12 365 SUPERFAMILY SSF51395 4 364 1.74E-121 T 10-03-2017 RG49_RS01795 63968336180e46a7b732b33ba7812b12 365 Gene3D G3DSA:3.20.20.70 4 364 1.3E-134 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS01795 63968336180e46a7b732b33ba7812b12 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 344 1.1E-89 T 10-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 SUPERFAMILY SSF46689 229 280 1.08E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 SUPERFAMILY SSF51182 43 97 5.07E-5 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 Pfam PF12852 Cupin 2 162 1.1E-18 T 10-03-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 Gene3D G3DSA:1.10.10.60 176 230 4.0E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 Gene3D G3DSA:1.10.10.60 231 279 2.1E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 276 6.8E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 260 6.8E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 SMART SM00342 193 276 6.0E-30 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 Gene3D G3DSA:2.60.120.10 41 88 3.0E-7 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 SUPERFAMILY SSF46689 176 224 1.28E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09660 685e6d0e68bdc2b72dd55f5c1470257c 284 Pfam PF12833 Helix-turn-helix domain 199 278 1.4E-20 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS07410 952a12588809478949035bbbb8605308 289 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.3E-39 T 10-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 RG49_RS07410 952a12588809478949035bbbb8605308 289 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.3E-39 T 10-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 RG49_RS07410 952a12588809478949035bbbb8605308 289 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.3E-39 T 10-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 RG49_RS07410 952a12588809478949035bbbb8605308 289 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.3E-39 T 10-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 RG49_RS07410 952a12588809478949035bbbb8605308 289 Gene3D G3DSA:3.40.50.720 2 119 2.2E-56 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS07410 952a12588809478949035bbbb8605308 289 Pfam PF02629 CoA binding domain 6 99 2.3E-31 T 10-03-2017 IPR003781 CoA-binding GO:0048037 RG49_RS07410 952a12588809478949035bbbb8605308 289 SUPERFAMILY SSF52210 123 288 4.97E-57 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS07410 952a12588809478949035bbbb8605308 289 Pfam PF00549 CoA-ligase 151 271 4.8E-20 T 10-03-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS07410 952a12588809478949035bbbb8605308 289 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 10-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 RG49_RS07410 952a12588809478949035bbbb8605308 289 PIRSF PIRSF001553 1 289 8.1E-136 T 10-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 RG49_RS07410 952a12588809478949035bbbb8605308 289 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 10-03-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site RG49_RS07410 952a12588809478949035bbbb8605308 289 Gene3D G3DSA:3.40.50.261 120 287 2.6E-78 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS07410 952a12588809478949035bbbb8605308 289 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 288 5.1E-146 T 10-03-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 RG49_RS07410 952a12588809478949035bbbb8605308 289 SMART SM00881 4 100 2.2E-37 T 10-03-2017 IPR003781 CoA-binding GO:0048037 RG49_RS07410 952a12588809478949035bbbb8605308 289 SUPERFAMILY SSF51735 1 122 1.08E-43 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Gene3D G3DSA:3.30.450.40 1 160 1.1E-46 T 10-03-2017 IPR029016 GAF domain-like RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 SUPERFAMILY SSF52009 293 413 1.57E-25 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Pfam PF05524 PEP-utilising enzyme, N-terminal 174 294 1.1E-23 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 SUPERFAMILY SSF47831 197 309 3.92E-26 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 SUPERFAMILY SSF55781 2 159 3.27E-30 T 10-03-2017 IPR029016 GAF domain-like RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 666 678 2.1E-24 T 10-03-2017 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 459 478 2.1E-24 T 10-03-2017 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 613 628 2.1E-24 T 10-03-2017 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 630 645 2.1E-24 T 10-03-2017 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 SUPERFAMILY SSF51621 419 715 4.45E-97 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 351 362 - T 10-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Pfam PF00391 PEP-utilising enzyme, mobile domain 320 391 1.7E-15 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 420 707 4.1E-110 T 10-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 175 729 5.0E-125 T 10-03-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 SMART SM00065 17 164 8.2E-29 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 613 631 - T 10-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Gene3D G3DSA:3.20.20.60 420 736 1.5E-100 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Gene3D G3DSA:3.50.30.10 301 414 8.3E-30 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Gene3D G3DSA:1.10.274.10 197 300 1.0E-33 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS20895 6d7044950507cb1eb4f2370fb1f2e6e3 748 Pfam PF01590 GAF domain 18 152 1.0E-14 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS23055 9675ae45136a897a184c15dedd7ec1c6 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 300 1.0E-69 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS23055 9675ae45136a897a184c15dedd7ec1c6 323 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 312 1.2E-146 T 10-03-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 RG49_RS23055 9675ae45136a897a184c15dedd7ec1c6 323 Gene3D G3DSA:3.40.50.1100 133 314 7.1E-73 T 10-03-2017 RG49_RS23055 9675ae45136a897a184c15dedd7ec1c6 323 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 10-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 RG49_RS23055 9675ae45136a897a184c15dedd7ec1c6 323 Gene3D G3DSA:3.40.50.1100 36 132 1.4E-38 T 10-03-2017 RG49_RS23055 9675ae45136a897a184c15dedd7ec1c6 323 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 312 7.4E-138 T 10-03-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 RG49_RS23055 9675ae45136a897a184c15dedd7ec1c6 323 SUPERFAMILY SSF53686 3 317 1.1E-97 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 123 4.1E-17 T 10-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 71 99 - T 10-03-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 PRINTS PR01650 Bacterial translocase SecE signature 65 85 1.0E-41 T 10-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 PRINTS PR01650 Bacterial translocase SecE signature 109 125 1.0E-41 T 10-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 PRINTS PR01650 Bacterial translocase SecE signature 89 109 1.0E-41 T 10-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 PRINTS PR01650 Bacterial translocase SecE signature 44 65 1.0E-41 T 10-03-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 Hamap MF_00422 Protein translocase subunit SecE [secE]. 67 121 13.188 T 10-03-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 Gene3D G3DSA:1.20.5.1030 64 123 3.1E-25 T 10-03-2017 RG49_RS14190 d7fac8c3b32b51f5695354313167117d 127 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 70 122 3.5E-20 T 10-03-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR00811 Bacterial general secretion pathway protein D signature 461 485 4.7E-37 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR00811 Bacterial general secretion pathway protein D signature 362 372 4.7E-37 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR00811 Bacterial general secretion pathway protein D signature 496 506 4.7E-37 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR00811 Bacterial general secretion pathway protein D signature 590 608 4.7E-37 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR00811 Bacterial general secretion pathway protein D signature 613 627 4.7E-37 T 10-03-2017 IPR001775 GspD/PilQ family RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR01032 Gene IV protein signature 446 469 3.3E-16 T 10-03-2017 RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR01032 Gene IV protein signature 553 581 3.3E-16 T 10-03-2017 RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR01032 Gene IV protein signature 486 509 3.3E-16 T 10-03-2017 RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 PRINTS PR01032 Gene IV protein signature 606 628 3.3E-16 T 10-03-2017 RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 Pfam PF00263 Bacterial type II and III secretion system protein 465 626 3.8E-51 T 10-03-2017 IPR004846 Type II/III secretion system GO:0009306 RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 Pfam PF03958 Bacterial type II/III secretion system short domain 145 206 1.7E-10 T 10-03-2017 IPR005644 NolW-like RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 Pfam PF03958 Bacterial type II/III secretion system short domain 211 277 3.1E-16 T 10-03-2017 IPR005644 NolW-like RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 Pfam PF03958 Bacterial type II/III secretion system short domain 285 362 6.3E-16 T 10-03-2017 IPR005644 NolW-like RG49_RS19990 9f6d1573b879d58322a83a173472002f 686 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 47 634 5.9E-166 T 10-03-2017 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 RG49_RS12405 398141247afad91a90f6ed2b9dab9514 300 Gene3D G3DSA:2.60.40.1090 180 300 9.3E-36 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12405 398141247afad91a90f6ed2b9dab9514 300 Pfam PF00419 Fimbrial protein 173 300 5.0E-10 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12405 398141247afad91a90f6ed2b9dab9514 300 SUPERFAMILY SSF49401 181 300 1.44E-27 T 10-03-2017 IPR008966 Adhesion domain RG49_RS12405 398141247afad91a90f6ed2b9dab9514 300 Gene3D G3DSA:2.60.40.1090 22 179 2.1E-83 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12405 398141247afad91a90f6ed2b9dab9514 300 SUPERFAMILY SSF49401 22 179 2.73E-70 T 10-03-2017 IPR008966 Adhesion domain RG49_RS12405 398141247afad91a90f6ed2b9dab9514 300 Pfam PF09160 FimH, mannose binding 24 168 5.1E-62 T 10-03-2017 IPR015243 FimH, mannose-binding domain RG49_RS20405 e0325ef50a69a1d0c677adb2e29fff2d 219 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 15 216 1.2E-72 T 10-03-2017 IPR005744 Hly-III GO:0016021|GO:0019835 RG49_RS20405 e0325ef50a69a1d0c677adb2e29fff2d 219 Pfam PF03006 Haemolysin-III related 12 209 2.3E-37 T 10-03-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 Gene3D G3DSA:3.40.720.10 240 405 2.0E-72 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 Gene3D G3DSA:3.40.720.10 1 113 2.0E-72 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 PIRSF PIRSF001491 1 407 9.1E-165 T 10-03-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 Gene3D G3DSA:3.30.70.1250 114 235 1.8E-52 T 10-03-2017 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 405 1.0E-209 T 10-03-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 SUPERFAMILY SSF143856 117 235 1.44E-49 T 10-03-2017 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 Pfam PF01676 Metalloenzyme superfamily 2 398 6.7E-47 T 10-03-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 Hamap MF_00740 Phosphopentomutase [deoB]. 1 407 55.848 T 10-03-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 SUPERFAMILY SSF53649 1 114 1.83E-69 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS12000 21ac8a5a62f847efa3e5b84009abb188 407 SUPERFAMILY SSF53649 236 406 1.83E-69 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS13645 bc046d47d24e0c4b6b47f88aff85c6bd 188 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 133 171 6.2E-5 T 10-03-2017 IPR010177 Doubled CXXCH motif RG49_RS13645 bc046d47d24e0c4b6b47f88aff85c6bd 188 Gene3D G3DSA:1.10.3820.10 28 173 4.6E-16 T 10-03-2017 RG49_RS13645 bc046d47d24e0c4b6b47f88aff85c6bd 188 TIGRFAM TIGR03146 cyt_nit_nrfB: cytochrome c nitrite reductase, pentaheme subunit 36 171 1.3E-59 T 10-03-2017 IPR017564 Cytochrome c nitrite reductase, pentahaem subunit GO:0006807|GO:0020037|GO:0042597 RG49_RS13645 bc046d47d24e0c4b6b47f88aff85c6bd 188 SUPERFAMILY SSF48695 5 169 4.95E-31 T 10-03-2017 IPR011031 Multihaem cytochrome RG49_RS13645 bc046d47d24e0c4b6b47f88aff85c6bd 188 Pfam PF13435 Cytochrome c554 and c-prime 37 83 0.013 T 10-03-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 RG49_RS19715 ab97702bee3d0ed01df83c80c1f43722 395 Gene3D G3DSA:3.90.1150.10 259 394 2.7E-40 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS19715 ab97702bee3d0ed01df83c80c1f43722 395 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 10-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 RG49_RS19715 ab97702bee3d0ed01df83c80c1f43722 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 391 1.3E-122 T 10-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 RG49_RS19715 ab97702bee3d0ed01df83c80c1f43722 395 Gene3D G3DSA:3.40.640.10 6 258 3.5E-74 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS19715 ab97702bee3d0ed01df83c80c1f43722 395 PIRSF PIRSF001434 1 395 1.9E-120 T 10-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 RG49_RS19715 ab97702bee3d0ed01df83c80c1f43722 395 SUPERFAMILY SSF53383 31 393 3.64E-90 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS19715 ab97702bee3d0ed01df83c80c1f43722 395 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 8 394 1.1E-170 T 10-03-2017 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 Gene3D G3DSA:3.40.50.970 335 537 4.2E-73 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 Gene3D G3DSA:3.40.50.970 1 171 1.4E-72 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 SUPERFAMILY SSF52518 1 174 5.44E-63 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 411 430 - T 10-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 374 522 2.9E-50 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 545 4.5E-216 T 10-03-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 Gene3D G3DSA:3.40.50.1220 183 334 2.3E-59 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 SUPERFAMILY SSF52518 357 546 6.08E-66 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 SUPERFAMILY SSF52467 181 342 2.95E-59 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 166 1.2E-56 T 10-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 RG49_RS15375 fe60172512a7444caa04007e7ebd1232 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 321 1.7E-42 T 10-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 RG49_RS05040 991cf2dec74cee8f23fdedc941c4dbb2 303 SUPERFAMILY SSF53067 1 300 3.58E-62 T 10-03-2017 RG49_RS05040 991cf2dec74cee8f23fdedc941c4dbb2 303 Hamap MF_01271 N-acetyl-D-glucosamine kinase [nagK]. 1 303 66.936 T 10-03-2017 IPR023505 N-acetyl-D-glucosamine kinase GO:0045127 KEGG: 00520+2.7.1.59|MetaCyc: PWY-6517|MetaCyc: PWY-6906 RG49_RS05040 991cf2dec74cee8f23fdedc941c4dbb2 303 Gene3D G3DSA:3.30.420.40 133 278 1.6E-49 T 10-03-2017 RG49_RS05040 991cf2dec74cee8f23fdedc941c4dbb2 303 ProSitePatterns PS01125 ROK family signature. 130 157 - T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS05040 991cf2dec74cee8f23fdedc941c4dbb2 303 Pfam PF00480 ROK family 2 300 4.5E-70 T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS05040 991cf2dec74cee8f23fdedc941c4dbb2 303 Gene3D G3DSA:3.30.420.40 1 132 1.2E-42 T 10-03-2017 RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 Pfam PF00571 CBS domain 206 261 6.2E-5 T 10-03-2017 IPR000644 CBS domain RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 Pfam PF00571 CBS domain 274 325 1.9E-5 T 10-03-2017 IPR000644 CBS domain RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 Gene3D G3DSA:3.10.580.10 201 325 6.7E-39 T 10-03-2017 RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 318 3.3E-135 T 10-03-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 Gene3D G3DSA:3.40.50.10490 17 200 8.1E-52 T 10-03-2017 RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 SUPERFAMILY SSF53697 14 325 4.45E-68 T 10-03-2017 RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 Pfam PF01380 SIS domain 46 177 1.0E-35 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS18655 6f1a50071c3b526adab8384d2f3d4af5 328 PIRSF PIRSF004692 1 328 7.6E-136 T 10-03-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 RG49_RS21565 16d6a44a03a4bbd3101e54c8b65efb7f 123 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 4 115 1.1E-38 T 10-03-2017 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 RG49_RS21565 16d6a44a03a4bbd3101e54c8b65efb7f 123 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 6 118 8.0E-62 T 10-03-2017 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 RG49_RS21565 16d6a44a03a4bbd3101e54c8b65efb7f 123 TIGRFAM TIGR00849 gutA: PTS system, glucitol/sorbitol-specific IIA component 1 123 4.1E-61 T 10-03-2017 IPR018454 Phosphotransferase system, glucitol/sorbitol-specific IIA component, subgroup GO:0005737|GO:0008982|GO:0009401 RG49_RS21565 16d6a44a03a4bbd3101e54c8b65efb7f 123 Gene3D G3DSA:2.40.33.40 1 119 1.0E-45 T 10-03-2017 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 RG49_RS21565 16d6a44a03a4bbd3101e54c8b65efb7f 123 SUPERFAMILY SSF141530 4 119 7.19E-38 T 10-03-2017 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 RG49_RS11310 3b4a18f012c60d06e90e4851e219312c 183 SMART SM00644 16 166 1.7E-61 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS11310 3b4a18f012c60d06e90e4851e219312c 183 Gene3D G3DSA:3.40.80.10 3 180 2.1E-70 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS11310 3b4a18f012c60d06e90e4851e219312c 183 SUPERFAMILY SSF55846 2 179 1.31E-67 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS11310 3b4a18f012c60d06e90e4851e219312c 183 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 30 167 1.4E-19 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS24885 e48bbfc80f60519df7abb02bce678851 720 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 508 711 6.9E-48 T 10-03-2017 IPR005702 Exopolysaccharide synthesis protein GO:0045226 RG49_RS24885 e48bbfc80f60519df7abb02bce678851 720 Gene3D G3DSA:3.40.50.300 527 706 2.9E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24885 e48bbfc80f60519df7abb02bce678851 720 Pfam PF02706 Chain length determinant protein 16 252 1.6E-50 T 10-03-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 RG49_RS24885 e48bbfc80f60519df7abb02bce678851 720 SUPERFAMILY SSF52540 527 707 4.68E-37 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24885 e48bbfc80f60519df7abb02bce678851 720 Pfam PF13614 AAA domain 538 650 2.2E-12 T 10-03-2017 IPR025669 AAA domain RG49_RS24885 e48bbfc80f60519df7abb02bce678851 720 Pfam PF13807 G-rich domain on putative tyrosine kinase 367 447 4.1E-30 T 10-03-2017 IPR032807 Tyrosine kinase, G-rich domain RG49_RS21355 74dc26128b76215968daf2543c090ded 208 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 130 145 - T 10-03-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 RG49_RS21355 74dc26128b76215968daf2543c090ded 208 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 5 206 3.0E-82 T 10-03-2017 RG49_RS21355 74dc26128b76215968daf2543c090ded 208 SUPERFAMILY SSF53335 12 204 2.59E-46 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS21355 74dc26128b76215968daf2543c090ded 208 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 2 207 8.5E-100 T 10-03-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 RG49_RS21355 74dc26128b76215968daf2543c090ded 208 Gene3D G3DSA:3.40.50.150 12 205 8.3E-64 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS21355 74dc26128b76215968daf2543c090ded 208 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 208 39.213 T 10-03-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 RG49_RS00565 2f797d95255ffffa73bb6b3a93d50c05 247 PIRSF PIRSF006325 1 243 4.3E-135 T 10-03-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 RG49_RS00565 2f797d95255ffffa73bb6b3a93d50c05 247 Gene3D G3DSA:3.40.50.150 19 241 8.8E-65 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00565 2f797d95255ffffa73bb6b3a93d50c05 247 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 3 242 42.944 T 10-03-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 RG49_RS00565 2f797d95255ffffa73bb6b3a93d50c05 247 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 4 242 1.2E-137 T 10-03-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 RG49_RS00565 2f797d95255ffffa73bb6b3a93d50c05 247 SUPERFAMILY SSF53335 20 242 1.52E-39 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00565 2f797d95255ffffa73bb6b3a93d50c05 247 Pfam PF13649 Methyltransferase domain 60 158 3.7E-14 T 10-03-2017 RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 90 3.8E-25 T 10-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 298 6.3E-120 T 10-03-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 Pfam PF00589 Phage integrase family 113 284 2.6E-56 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 SUPERFAMILY SSF56349 106 296 5.0E-60 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 298 58.806 T 10-03-2017 IPR023009 Tyrosine recombinase XerC/XerD RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 4 298 66.874 T 10-03-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 SUPERFAMILY SSF47823 4 100 8.04E-36 T 10-03-2017 IPR010998 Integrase, Lambda-type, N-terminal RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 Gene3D G3DSA:1.10.443.10 113 289 7.8E-60 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS20430 a1b221e930a1b909bc57d6057389959d 298 Gene3D G3DSA:1.10.150.130 7 99 4.2E-30 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS14430 26a75427ac162c3017fe72015b267e14 386 PIRSF PIRSF001434 1 384 6.4E-130 T 10-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 RG49_RS14430 26a75427ac162c3017fe72015b267e14 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 190 204 - T 10-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 RG49_RS14430 26a75427ac162c3017fe72015b267e14 386 Gene3D G3DSA:3.90.1150.10 250 383 2.2E-47 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS14430 26a75427ac162c3017fe72015b267e14 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 380 4.2E-141 T 10-03-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 RG49_RS14430 26a75427ac162c3017fe72015b267e14 386 Gene3D G3DSA:3.40.640.10 5 246 6.0E-88 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS14430 26a75427ac162c3017fe72015b267e14 386 SUPERFAMILY SSF53383 5 381 1.24E-118 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS14430 26a75427ac162c3017fe72015b267e14 386 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 3 382 2.1E-212 T 10-03-2017 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48 RG49_RS08615 057c039d5e1ce6bca6144cf710d89113 259 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 6 251 1.6E-115 T 10-03-2017 IPR005226 UPF0014 family RG49_RS08615 057c039d5e1ce6bca6144cf710d89113 259 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 245 9.9E-83 T 10-03-2017 IPR005226 UPF0014 family RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 Gene3D G3DSA:1.10.101.10 234 271 1.9E-22 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 Gene3D G3DSA:1.10.101.10 314 357 1.9E-22 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 Pfam PF03734 L,D-transpeptidase catalytic domain 377 543 6.7E-31 T 10-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 Pfam PF01471 Putative peptidoglycan binding domain 315 348 5.8E-7 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 SUPERFAMILY SSF47090 313 356 2.67E-9 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 SUPERFAMILY SSF141523 375 428 1.19E-20 T 10-03-2017 RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 SUPERFAMILY SSF141523 484 533 1.19E-20 T 10-03-2017 RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 Gene3D G3DSA:2.40.440.10 486 534 1.5E-14 T 10-03-2017 RG49_RS06110 c4a9794721b52a94126b21c77343e1f3 615 Gene3D G3DSA:2.40.440.10 370 419 1.5E-14 T 10-03-2017 RG49_RS22350 d67830c3cf09347513af4f49e92fd5e5 290 Pfam PF01263 Aldose 1-epimerase 3 285 1.2E-50 T 10-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 RG49_RS22350 d67830c3cf09347513af4f49e92fd5e5 290 SUPERFAMILY SSF74650 2 288 5.71E-51 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS22350 d67830c3cf09347513af4f49e92fd5e5 290 Gene3D G3DSA:2.70.98.10 2 287 5.9E-22 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS06795 f19ce7832e4c8c77dac3364c7b25a5d4 410 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 88 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS06795 f19ce7832e4c8c77dac3364c7b25a5d4 410 Pfam PF07690 Major Facilitator Superfamily 27 361 1.9E-28 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS06795 f19ce7832e4c8c77dac3364c7b25a5d4 410 SUPERFAMILY SSF103473 21 399 2.22E-45 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS06795 f19ce7832e4c8c77dac3364c7b25a5d4 410 Gene3D G3DSA:1.20.1250.20 22 202 1.2E-23 T 10-03-2017 RG49_RS22900 7835fcb0de1f99090abb5a94278e0fd6 278 SUPERFAMILY SSF53067 141 260 1.11E-21 T 10-03-2017 RG49_RS22900 7835fcb0de1f99090abb5a94278e0fd6 278 Gene3D G3DSA:3.30.420.40 148 246 2.9E-35 T 10-03-2017 RG49_RS22900 7835fcb0de1f99090abb5a94278e0fd6 278 TIGRFAM TIGR02529 EutJ: ethanolamine utilization protein EutJ family protein 33 267 1.3E-112 T 10-03-2017 IPR013366 Ethanolamine utilisation EutJ RG49_RS22900 7835fcb0de1f99090abb5a94278e0fd6 278 Pfam PF14450 Cell division protein FtsA 141 246 1.3E-9 T 10-03-2017 RG49_RS22900 7835fcb0de1f99090abb5a94278e0fd6 278 Gene3D G3DSA:3.30.420.40 13 147 2.2E-22 T 10-03-2017 RG49_RS22900 7835fcb0de1f99090abb5a94278e0fd6 278 SUPERFAMILY SSF53067 30 131 3.11E-9 T 10-03-2017 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 Gene3D G3DSA:3.20.20.60 4 417 2.9E-172 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 ProSitePatterns PS00161 Isocitrate lyase signature. 193 198 - T 10-03-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 SUPERFAMILY SSF51621 4 417 7.18E-157 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 256 434 6.2E-94 T 10-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 8 255 3.7E-124 T 10-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 Pfam PF00463 Isocitrate lyase family 8 255 6.0E-61 T 10-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 Pfam PF00463 Isocitrate lyase family 256 434 2.0E-49 T 10-03-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 RG49_RS13995 f995a4b2b1deaa2b2ef3164261dcedc9 434 PIRSF PIRSF001362 1 434 6.4E-229 T 10-03-2017 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 Gene3D G3DSA:1.10.260.40 2 53 3.2E-25 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 SUPERFAMILY SSF53822 61 329 2.9E-89 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 SUPERFAMILY SSF47413 2 59 3.26E-17 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.9E-21 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.2E-6 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.2E-6 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 SMART SM00354 1 71 1.9E-35 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 Pfam PF13377 Periplasmic binding protein-like domain 169 329 1.1E-40 T 10-03-2017 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 Gene3D G3DSA:3.40.50.2300 177 306 3.4E-54 T 10-03-2017 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 10-03-2017 RG49_RS15445 51be117e54ea350e7ab4780374f17d15 330 Gene3D G3DSA:3.40.50.2300 54 176 4.7E-43 T 10-03-2017 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 PIRSF PIRSF000349 1 193 1.7E-87 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 10-03-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 SUPERFAMILY SSF54719 84 192 2.23E-45 T 10-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 2.1E-40 T 10-03-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 SUPERFAMILY SSF46609 1 84 1.22E-36 T 10-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 82 1.5E-35 T 10-03-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 Gene3D G3DSA:1.10.287.990 20 82 3.4E-26 T 10-03-2017 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 2.2E-22 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.2E-22 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.2E-22 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 2.2E-22 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01765 ce422a1e705d91080141d9bb318b50ce 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 2.2E-22 T 10-03-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS22225 09824aca3ccb5f945b217d95f424c697 243 Gene3D G3DSA:3.20.20.70 3 242 2.7E-115 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS22225 09824aca3ccb5f945b217d95f424c697 243 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 238 3.1E-108 T 10-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 RG49_RS22225 09824aca3ccb5f945b217d95f424c697 243 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 7.1E-118 T 10-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 RG49_RS22225 09824aca3ccb5f945b217d95f424c697 243 SUPERFAMILY SSF63892 4 241 4.18E-104 T 10-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 RG49_RS22225 09824aca3ccb5f945b217d95f424c697 243 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 243 136.685 T 10-03-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 RG49_RS23740 5db339fe6f6cf4892a0ffea8899c0415 575 Pfam PF12034 Domain of unknown function (DUF3520) 393 568 8.1E-65 T 10-03-2017 IPR021908 Protein of unknown function DUF3520 RG49_RS23740 5db339fe6f6cf4892a0ffea8899c0415 575 Pfam PF00092 von Willebrand factor type A domain 216 376 5.2E-23 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS23740 5db339fe6f6cf4892a0ffea8899c0415 575 SUPERFAMILY SSF53300 215 390 3.14E-35 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS23740 5db339fe6f6cf4892a0ffea8899c0415 575 Gene3D G3DSA:3.40.50.410 216 391 8.0E-24 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS23740 5db339fe6f6cf4892a0ffea8899c0415 575 SMART SM00327 214 390 5.2E-31 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS23740 5db339fe6f6cf4892a0ffea8899c0415 575 Pfam PF12450 von Willebrand factor 101 199 7.0E-33 T 10-03-2017 IPR022156 Uncharacterised protein YfbK, N-terminal RG49_RS09205 ad28a8bffcd43132168d795293745983 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 27.237 T 10-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 RG49_RS09205 ad28a8bffcd43132168d795293745983 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 10-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 RG49_RS09205 ad28a8bffcd43132168d795293745983 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 266 2.7E-38 T 10-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 RG49_RS09205 ad28a8bffcd43132168d795293745983 269 SUPERFAMILY SSF51735 3 159 7.04E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09205 ad28a8bffcd43132168d795293745983 269 PIRSF PIRSF000193 2 269 5.8E-100 T 10-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 RG49_RS09205 ad28a8bffcd43132168d795293745983 269 Gene3D G3DSA:1.10.3730.10 162 266 1.2E-42 T 10-03-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 RG49_RS09205 ad28a8bffcd43132168d795293745983 269 Gene3D G3DSA:3.40.50.720 1 159 1.6E-51 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09205 ad28a8bffcd43132168d795293745983 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 4.4E-93 T 10-03-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 RG49_RS09205 ad28a8bffcd43132168d795293745983 269 SUPERFAMILY SSF48179 162 268 3.74E-37 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS09205 ad28a8bffcd43132168d795293745983 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 1.5E-24 T 10-03-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal RG49_RS06665 dea321628fddfda59e4678d70a8e1743 175 Pfam PF05926 Phage head completion protein (GPL) 37 175 4.7E-54 T 10-03-2017 IPR009225 Bacteriophage head completion protein GpL GO:0019069 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 SMART SM00382 487 654 2.2E-6 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 SMART SM00382 206 352 2.1E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 734 0.0 T 10-03-2017 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Gene3D G3DSA:3.40.50.300 442 663 3.3E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 342 4.9E-13 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 SUPERFAMILY SSF52540 169 426 1.77E-68 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 SMART SM01086 653 744 7.4E-36 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Gene3D G3DSA:1.10.8.60 664 754 2.2E-32 T 10-03-2017 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 302 314 - T 10-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Pfam PF07724 AAA domain (Cdc48 subfamily) 486 647 1.8E-47 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Gene3D G3DSA:3.40.50.300 167 350 5.8E-42 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Gene3D G3DSA:1.10.1780.10 1 141 1.4E-45 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 SUPERFAMILY SSF52540 437 748 9.85E-78 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 7.7E-15 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 533 551 1.2E-35 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 562 580 1.2E-35 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 595 609 1.2E-35 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 491 509 1.2E-35 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Gene3D G3DSA:1.10.8.60 352 435 4.4E-30 T 10-03-2017 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 SUPERFAMILY SSF81923 1 141 1.96E-58 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 518 536 - T 10-03-2017 IPR028299 ClpA/B, conserved site 2 RG49_RS06340 a32c23cc0d6ccbb5e17f484494775219 758 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 653 733 7.1E-25 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 SMART SM00359 3 88 1.2E-19 T 10-03-2017 IPR002478 PUA domain GO:0003723 RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 Gene3D G3DSA:3.40.50.150 185 395 7.4E-62 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 SUPERFAMILY SSF88697 4 72 5.04E-17 T 10-03-2017 IPR015947 PUA-like domain RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 174 371 6.5E-30 T 10-03-2017 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 Gene3D G3DSA:2.30.130.10 4 71 1.7E-27 T 10-03-2017 IPR015947 PUA-like domain RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 Hamap MF_01857 Ribosomal RNA large subunit methyltransferase I [rlmI]. 1 396 70.742 T 10-03-2017 IPR023542 rRNA large subunit methyltransferase I GO:0008649 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 SUPERFAMILY SSF53335 79 392 3.29E-73 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS05875 517bba5c696b1624b2e7a3441e00b9d9 396 Gene3D G3DSA:3.30.750.80 73 180 9.6E-35 T 10-03-2017 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 Gene3D G3DSA:3.40.50.20 3 84 7.3E-28 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 PIRSF PIRSF039102 37 306 5.9E-100 T 10-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 SUPERFAMILY SSF56059 97 302 4.38E-57 T 10-03-2017 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 Pfam PF01820 D-ala D-ala ligase N-terminus 4 86 6.4E-21 T 10-03-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 248 276 - T 10-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 Gene3D G3DSA:3.30.470.20 85 103 7.7E-53 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 Gene3D G3DSA:3.30.470.20 181 305 7.7E-53 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 305 1.5E-112 T 10-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 63 74 - T 10-03-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 Gene3D G3DSA:3.30.1490.20 107 180 2.1E-26 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 SUPERFAMILY SSF52440 3 96 1.63E-29 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 306 36.485 T 10-03-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11395 54e611311e0e2a239edc3e7c5749607a 306 Pfam PF07478 D-ala D-ala ligase C-terminus 103 303 1.5E-72 T 10-03-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 686 767 3.7E-17 T 10-03-2017 IPR009647 Penicillin-binding, C-terminal RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 37 770 3.5E-277 T 10-03-2017 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 Pfam PF00912 Transglycosylase 61 226 3.1E-51 T 10-03-2017 IPR001264 Glycosyl transferase, family 51 RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 SUPERFAMILY SSF56601 208 637 3.96E-92 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 SUPERFAMILY SSF53955 39 258 5.34E-66 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 Pfam PF00905 Penicillin binding protein transpeptidase domain 310 519 3.6E-11 T 10-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 Gene3D G3DSA:1.10.3810.10 59 229 1.0E-54 T 10-03-2017 RG49_RS22475 6fc8f588db9dc8f28cd8aa8f6e5614cd 770 Gene3D G3DSA:3.40.710.10 230 616 7.0E-74 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 3 527 7.3E-284 T 10-03-2017 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 Gene3D G3DSA:2.30.38.10 360 430 1.2E-21 T 10-03-2017 RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 Pfam PF00501 AMP-binding enzyme 37 437 1.5E-75 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 SUPERFAMILY SSF56801 5 532 4.19E-125 T 10-03-2017 RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 Gene3D G3DSA:3.40.50.980 36 191 2.2E-26 T 10-03-2017 RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 Gene3D G3DSA:3.30.300.30 432 533 5.3E-27 T 10-03-2017 RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 Gene3D G3DSA:3.40.50.980 192 349 2.7E-32 T 10-03-2017 RG49_RS08160 c4380653142ac6be1c2307929583d88d 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 520 3.6E-12 T 10-03-2017 IPR025110 AMP-binding enzyme C-terminal domain RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 Pfam PF00902 Sec-independent protein translocase protein (TatC) 12 221 2.6E-67 T 10-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 8 35 1.1E-50 T 10-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 1.1E-50 T 10-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 1.1E-50 T 10-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 1.1E-50 T 10-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 243 18.256 T 10-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 226 7.6E-81 T 10-03-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 RG49_RS14995 d13b96f277bdc0e5fde0c1cb180b1c95 258 ProSitePatterns PS01218 TatC family signature. 154 173 - T 10-03-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 Pfam PF13522 Glutamine amidotransferase domain 65 182 2.4E-21 T 10-03-2017 RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 609 6.1E-271 T 10-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 Gene3D G3DSA:3.40.50.10490 445 609 3.0E-70 T 10-03-2017 RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 SUPERFAMILY SSF53697 245 609 1.16E-114 T 10-03-2017 RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 Pfam PF01380 SIS domain 462 591 1.5E-30 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 Pfam PF01380 SIS domain 289 418 2.7E-34 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 SUPERFAMILY SSF56235 2 232 1.29E-75 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 Gene3D G3DSA:3.40.50.10490 245 444 1.7E-65 T 10-03-2017 RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 Gene3D G3DSA:3.60.20.10 2 238 1.2E-80 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS15565 3d0070cce1db51f60f49580883bc373d 609 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 609 41.611 T 10-03-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 Gene3D G3DSA:2.30.30.60 945 994 8.8E-18 T 10-03-2017 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 SUPERFAMILY SSF82689 998 1097 4.71E-26 T 10-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 SUPERFAMILY SSF81665 683 770 1.44E-5 T 10-03-2017 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 SUPERFAMILY SSF81665 512 594 1.44E-5 T 10-03-2017 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 SUPERFAMILY SSF81665 844 900 1.44E-5 T 10-03-2017 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 Gene3D G3DSA:3.30.70.100 999 1084 4.1E-23 T 10-03-2017 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 SUPERFAMILY SSF82861 845 928 1.22E-8 T 10-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 959 993 - T 10-03-2017 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 Pfam PF12795 Mechanosensitive ion channel porin domain 50 289 4.4E-64 T 10-03-2017 IPR024393 Mechanosensitive ion channel MscS, porin domain RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 SUPERFAMILY SSF50182 930 995 6.87E-17 T 10-03-2017 IPR010920 LSM domain RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 Pfam PF00924 Mechanosensitive ion channel 887 1086 2.5E-61 T 10-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 RG49_RS08775 fc6cf84d6585a3b81e72f45f917c76b3 1120 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 509 826 4.1E-96 T 10-03-2017 IPR025692 Mechanosensitive ion channel inner membrane domain 1 RG49_RS10700 2f207d102fa92027c361ae168c93143e 405 Pfam PF06812 ImpA, N-terminal, type VI secretion system 12 113 9.1E-18 T 10-03-2017 IPR010657 ImpA, N-terminal RG49_RS10700 2f207d102fa92027c361ae168c93143e 405 Pfam PF12486 Type VI secretion system, EvfB, or VasL 254 390 1.8E-16 T 10-03-2017 IPR021069 ImpA, C-terminal RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 7 447 1.4E-152 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 307 323 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 Pfam PF00083 Sugar (and other) transporter 18 450 1.9E-141 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 PRINTS PR00171 Sugar transporter signature 26 36 2.0E-23 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 PRINTS PR00171 Sugar transporter signature 262 272 2.0E-23 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 PRINTS PR00171 Sugar transporter signature 352 373 2.0E-23 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 PRINTS PR00171 Sugar transporter signature 375 387 2.0E-23 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 PRINTS PR00171 Sugar transporter signature 109 128 2.0E-23 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 SUPERFAMILY SSF103473 13 448 1.57E-77 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 Gene3D G3DSA:1.20.1250.20 20 206 1.2E-29 T 10-03-2017 RG49_RS20170 fbf57f1403d47a941868a613ff5fdbf7 464 Gene3D G3DSA:1.20.1250.20 244 449 1.7E-26 T 10-03-2017 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 Gene3D G3DSA:3.20.20.100 5 271 1.2E-103 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 SUPERFAMILY SSF51430 5 268 6.15E-91 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 10-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 PRINTS PR00069 Aldo-keto reductase signature 123 140 2.5E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 PRINTS PR00069 Aldo-keto reductase signature 157 186 2.5E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.5E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 PRINTS PR00069 Aldo-keto reductase signature 91 109 2.5E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 2.5E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 10-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 Pfam PF00248 Aldo/keto reductase family 201 260 5.1E-10 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 Pfam PF00248 Aldo/keto reductase family 18 192 1.9E-39 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS19690 88e41fc450178b85b56d7a3a9feda349 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 10-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 Gene3D G3DSA:3.40.50.1000 100 239 9.5E-47 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 95 209 4.8E-15 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 124 204 1.8E-12 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 Gene3D G3DSA:1.10.150.240 22 99 4.9E-27 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 10 239 1.9E-102 T 10-03-2017 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 7 240 36.757 T 10-03-2017 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 123 136 1.8E-13 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 170 1.8E-13 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 1.8E-13 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 192 1.8E-13 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 209 4.9E-37 T 10-03-2017 IPR023214 HAD-like domain RG49_RS17660 c2bd1895e9791cd95c22fb93b614e8a9 252 SUPERFAMILY SSF56784 3 239 1.36E-59 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 SUPERFAMILY SSF116726 207 271 5.23E-8 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 Pfam PF02080 TrkA-C domain 212 270 7.4E-7 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 Pfam PF02080 TrkA-C domain 291 360 8.0E-11 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 Gene3D G3DSA:3.30.70.1450 221 278 2.2E-4 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 Hamap MF_01016 Putative transport protein YidE [yidE]. 1 553 58.832 T 10-03-2017 IPR023018 Transport protein YidE, putative RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 Gene3D G3DSA:3.30.70.1450 288 360 2.2E-11 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 16 166 1.8E-38 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 379 533 2.7E-52 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 Pfam PF06826 Predicted Permease Membrane Region 374 546 1.2E-47 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 Pfam PF06826 Predicted Permease Membrane Region 11 179 2.1E-41 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS15800 2d6d68e3cf223c57bba82776f0b53d98 553 SUPERFAMILY SSF116726 277 360 9.42E-14 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 Pfam PF01106 NifU-like domain 111 177 2.6E-20 T 10-03-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 191 46.432 T 10-03-2017 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 SUPERFAMILY SSF89360 1 97 2.16E-20 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 SUPERFAMILY SSF117916 95 184 2.14E-25 T 10-03-2017 RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 2 191 1.7E-100 T 10-03-2017 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 Gene3D G3DSA:2.60.300.12 1 97 2.9E-17 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 119 177 2.0E-28 T 10-03-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 RG49_RS17495 8924b747df2ef2fc99fc59d93ddb35c8 191 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 99 1.4E-12 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.4E-6 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.4E-6 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 SUPERFAMILY SSF46785 5 60 2.11E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 62 2.3E-20 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 Gene3D G3DSA:1.10.10.10 1 55 6.0E-8 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 Hamap MF_01563 HTH-type transcriptional regulator UlaR [ulaR]. 1 251 71.049 T 10-03-2017 IPR023711 Transcription regulator HTH, UlaR GO:0005737|GO:0045892 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 SUPERFAMILY SSF100950 75 234 1.67E-23 T 10-03-2017 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 Pfam PF00455 DeoR C terminal sensor domain 76 230 2.2E-37 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 SMART SM01134 74 232 3.4E-38 T 10-03-2017 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 SMART SM00420 6 58 4.8E-23 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS12955 fa6722683dbb832b1c9f0e37fbd9c1a0 251 Gene3D G3DSA:3.40.50.1360 76 215 2.8E-4 T 10-03-2017 RG49_RS10145 1d98afeb1f94c6f084cf5d8ee9f4bf00 564 SUPERFAMILY SSF52540 1 86 5.31E-24 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10145 1d98afeb1f94c6f084cf5d8ee9f4bf00 564 SUPERFAMILY SSF52540 163 322 5.31E-24 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10145 1d98afeb1f94c6f084cf5d8ee9f4bf00 564 Pfam PF13175 AAA ATPase domain 1 44 2.7E-11 T 10-03-2017 RG49_RS10145 1d98afeb1f94c6f084cf5d8ee9f4bf00 564 Pfam PF13175 AAA ATPase domain 191 304 4.2E-17 T 10-03-2017 RG49_RS10145 1d98afeb1f94c6f084cf5d8ee9f4bf00 564 Gene3D G3DSA:3.40.50.300 166 320 6.5E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10145 1d98afeb1f94c6f084cf5d8ee9f4bf00 564 Gene3D G3DSA:3.40.50.300 1 117 6.5E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10540 a7dd34640dfd0c50d302f2c4aebba93f 165 SUPERFAMILY SSF143422 1 125 1.12E-29 T 10-03-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 RG49_RS10540 a7dd34640dfd0c50d302f2c4aebba93f 165 Gene3D G3DSA:3.30.70.1290 11 123 7.2E-8 T 10-03-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 RG49_RS10540 a7dd34640dfd0c50d302f2c4aebba93f 165 SMART SM01321 9 119 9.1E-28 T 10-03-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 RG49_RS08290 7ef28bda546d322595f6ca023cb98f2f 458 ProSitePatterns PS00218 Amino acid permeases signature. 52 82 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS08290 7ef28bda546d322595f6ca023cb98f2f 458 PIRSF PIRSF006060 4 457 1.6E-77 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS08290 7ef28bda546d322595f6ca023cb98f2f 458 Pfam PF00324 Amino acid permease 27 452 6.0E-119 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 SUPERFAMILY SSF51905 356 447 6.79E-75 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 SUPERFAMILY SSF51905 4 255 6.79E-75 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 SUPERFAMILY SSF46977 425 522 1.14E-31 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 Gene3D G3DSA:3.90.700.10 244 348 6.2E-37 T 10-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 370 377 6.7E-5 T 10-03-2017 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.7E-5 T 10-03-2017 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 Gene3D G3DSA:1.20.58.100 419 521 6.0E-35 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.9E-11 T 10-03-2017 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 7.9E-11 T 10-03-2017 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 Pfam PF02910 Fumarate reductase flavoprotein C-term 441 521 3.7E-14 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 7 520 8.5E-241 T 10-03-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 Pfam PF00890 FAD binding domain 10 392 2.2E-106 T 10-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 Gene3D G3DSA:3.50.50.60 349 409 7.4E-103 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 Gene3D G3DSA:3.50.50.60 3 243 7.4E-103 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22165 5032b65d1cea4cc0501af1d179a93673 540 SUPERFAMILY SSF56425 238 353 1.94E-40 T 10-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 5.4E-10 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 5.4E-10 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 5.4E-10 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 2.2E-29 T 10-03-2017 IPR032305 GTP-binding protein, middle domain RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 SUPERFAMILY SSF52540 197 373 9.55E-41 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 SUPERFAMILY SSF54980 365 422 4.03E-14 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 1.1E-30 T 10-03-2017 IPR025121 GTPase HflX, N-terminal RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 Gene3D G3DSA:3.40.50.300 198 361 2.1E-36 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 Pfam PF01926 50S ribosome-binding GTPase 200 318 1.6E-21 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 Hamap MF_00900 GTPase HflX [hflX]. 27 390 47.461 T 10-03-2017 IPR016496 GTPase HflX GO:0005525 RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 361 5.7E-155 T 10-03-2017 IPR016496 GTPase HflX GO:0005525 RG49_RS13050 75bda29793b86a71a35e27268d4416b6 426 PIRSF PIRSF006809 3 419 6.8E-152 T 10-03-2017 IPR016496 GTPase HflX GO:0005525 RG49_RS06920 7b71740b12a1db903033d68260a33d5b 155 SUPERFAMILY SSF47979 95 150 4.84E-15 T 10-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 RG49_RS06920 7b71740b12a1db903033d68260a33d5b 155 Gene3D G3DSA:1.10.10.10 36 103 8.1E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06920 7b71740b12a1db903033d68260a33d5b 155 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 38 92 1.1E-10 T 10-03-2017 IPR022687 DTXR-type HTH domain GO:0003677 RG49_RS06920 7b71740b12a1db903033d68260a33d5b 155 SUPERFAMILY SSF46785 48 117 1.89E-12 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06920 7b71740b12a1db903033d68260a33d5b 155 SMART SM00529 56 155 1.6E-44 T 10-03-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 RG49_RS06920 7b71740b12a1db903033d68260a33d5b 155 Gene3D G3DSA:1.10.60.10 107 150 2.7E-20 T 10-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 RG49_RS06920 7b71740b12a1db903033d68260a33d5b 155 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 95 149 1.2E-14 T 10-03-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 Gene3D G3DSA:3.30.870.10 502 685 8.5E-67 T 10-03-2017 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 SUPERFAMILY SSF143724 107 313 1.43E-59 T 10-03-2017 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 SUPERFAMILY SSF56024 503 684 3.14E-68 T 10-03-2017 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 SUPERFAMILY SSF140356 3 105 8.11E-34 T 10-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 7 679 3.5E-257 T 10-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 Gene3D G3DSA:3.30.1840.10 106 300 9.2E-52 T 10-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 Pfam PF13090 Polyphosphate kinase C-terminal domain 333 678 3.6E-143 T 10-03-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 Hamap MF_00347 Polyphosphate kinase [ppk]. 4 683 36.345 T 10-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 PIRSF PIRSF015589 1 688 6.0E-240 T 10-03-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 Pfam PF13089 Polyphosphate kinase N-terminal domain 7 109 3.0E-31 T 10-03-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 Pfam PF02503 Polyphosphate kinase middle domain 119 319 1.4E-41 T 10-03-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 Gene3D G3DSA:3.30.870.10 327 501 1.4E-74 T 10-03-2017 RG49_RS22640 2d49aa196f947cd0875399f792333c9a 688 SUPERFAMILY SSF56024 320 499 1.48E-56 T 10-03-2017 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 14 31 - T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 311 317 3.2E-23 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 9 21 3.2E-23 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 82 94 3.2E-23 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 3.2E-23 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 359 3.2E-23 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 22 32 3.2E-23 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 SUPERFAMILY SSF51905 9 322 1.81E-44 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 Pfam PF01266 FAD dependent oxidoreductase 10 358 4.7E-51 T 10-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 352 362 - T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 Pfam PF04324 BFD-like [2Fe-2S] binding domain 432 484 6.2E-10 T 10-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 Gene3D G3DSA:3.50.50.60 7 241 2.2E-42 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23895 d900316f35f93d7ed5b6392a307ddcb3 542 TIGRFAM TIGR03377 glycerol3P_GlpA: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit 10 539 1.5E-266 T 10-03-2017 IPR017752 Glycerol-3-phosphate dehydrogenase, GlpA subunit GO:0004368|GO:0005886|GO:0010181|GO:0046174|GO:0050660|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 RG49_RS24335 41a1479eeb79d18fed416f7416096c32 416 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 201 412 4.0E-66 T 10-03-2017 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 RG49_RS24335 41a1479eeb79d18fed416f7416096c32 416 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.0E-21 T 10-03-2017 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 RG49_RS24335 41a1479eeb79d18fed416f7416096c32 416 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 412 6.5E-156 T 10-03-2017 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 RG49_RS02505 38b616c6eef1665d15a0661efb303c4a 67 TIGRFAM TIGR03318 YdfZ_fam: putative selenium-binding protein YdfZ 1 65 3.9E-38 T 10-03-2017 IPR017704 Putative selenium-binding protein YdfZ RG49_RS02505 38b616c6eef1665d15a0661efb303c4a 67 Pfam PF14001 YdfZ protein 3 65 1.1E-33 T 10-03-2017 IPR017704 Putative selenium-binding protein YdfZ RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 Pfam PF08402 TOBE domain 278 348 1.5E-8 T 10-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 Gene3D G3DSA:3.40.50.300 4 235 1.0E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 SMART SM00382 29 326 1.2E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 SUPERFAMILY SSF50331 237 355 3.64E-28 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 Gene3D G3DSA:2.40.50.140 283 340 2.1E-17 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 SUPERFAMILY SSF52540 4 243 5.9E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 Gene3D G3DSA:2.40.50.100 240 282 7.0E-10 T 10-03-2017 RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 Gene3D G3DSA:2.40.50.100 342 356 7.0E-10 T 10-03-2017 RG49_RS17330 c6e38e40dae5d159123b4a50d9ee7e15 356 Pfam PF00005 ABC transporter 21 162 4.3E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 Pfam PF00137 ATP synthase subunit C 11 69 1.6E-9 T 10-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 Gene3D G3DSA:1.20.20.10 2 77 5.0E-31 T 10-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 12 31 1.6E-8 T 10-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 50 75 1.6E-8 T 10-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 33 48 1.6E-8 T 10-03-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 77 1.9E-31 T 10-03-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 SUPERFAMILY SSF81333 3 77 4.58E-18 T 10-03-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 77 14.331 T 10-03-2017 RG49_RS15525 56b533cc370c1e28d908debdcf79489b 79 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 10-03-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 Hamap MF_01068 Glucans biosynthesis protein D [mdoD]. 1 544 61.132 T 10-03-2017 IPR023724 Glucan biosynthesis, MdoD RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 PIRSF PIRSF006281 1 538 1.4E-207 T 10-03-2017 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 SUPERFAMILY SSF81296 423 537 1.89E-27 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 SUPERFAMILY SSF74650 45 421 6.28E-146 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 32 9.0E-4 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 Gene3D G3DSA:2.70.98.10 44 422 1.2E-160 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 45 534 1.4E-180 T 10-03-2017 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 RG49_RS03290 eabb81edb38a365ad528b5758b700e4d 551 Gene3D G3DSA:2.60.40.10 423 545 2.4E-32 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 233 3.0E-51 T 10-03-2017 RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 2.6E-9 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.6E-9 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 2.6E-9 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 0.0038 T 10-03-2017 RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 SUPERFAMILY SSF51735 6 234 1.27E-64 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 9.9E-36 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 9.9E-36 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 9.9E-36 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 9.9E-36 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 9.9E-36 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.9E-36 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS12645 5dbb9b1ef284e84437ace0b13f2448bb 237 Gene3D G3DSA:3.40.50.720 2 234 4.7E-64 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03265 50fecc5b923d76815f2f19bedf28aff4 330 Pfam PF03595 Voltage-dependent anion channel 8 305 4.3E-39 T 10-03-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 RG49_RS03265 50fecc5b923d76815f2f19bedf28aff4 330 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 9 312 1.2E-112 T 10-03-2017 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 SMART SM00840 341 402 3.1E-29 T 10-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 Gene3D G3DSA:1.20.120.640 306 392 7.7E-30 T 10-03-2017 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 461 39.849 T 10-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 460 2.4E-201 T 10-03-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 3.2E-146 T 10-03-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 3.6E-30 T 10-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 3.6E-30 T 10-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 3.6E-30 T 10-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 3.6E-30 T 10-03-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 Pfam PF09190 DALR domain 341 402 6.7E-26 T 10-03-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 SUPERFAMILY SSF47323 316 460 3.79E-45 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 SUPERFAMILY SSF52374 1 313 1.38E-103 T 10-03-2017 RG49_RS08445 5a58d31c0d86a92dbede48e543564727 461 Gene3D G3DSA:3.40.50.620 20 305 7.5E-114 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS04930 02ae5257b7d6d50c0741e87f2fa8d4cc 217 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 76 90 - T 10-03-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS04930 02ae5257b7d6d50c0741e87f2fa8d4cc 217 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 45 217 2.0E-61 T 10-03-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS04930 02ae5257b7d6d50c0741e87f2fa8d4cc 217 SUPERFAMILY SSF55120 37 216 3.04E-43 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS04930 02ae5257b7d6d50c0741e87f2fa8d4cc 217 Pfam PF00849 RNA pseudouridylate synthase 41 186 5.7E-13 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 SUPERFAMILY SSF52374 416 668 1.01E-140 T 10-03-2017 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 SUPERFAMILY SSF52374 5 226 1.01E-140 T 10-03-2017 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Gene3D G3DSA:3.40.50.620 425 573 2.1E-151 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Gene3D G3DSA:3.40.50.620 618 647 2.1E-151 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Gene3D G3DSA:3.40.50.620 4 222 2.1E-151 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 4.1E-52 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 4.1E-52 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 4.1E-52 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 4.1E-52 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 4.1E-52 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 4.1E-52 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 4.1E-52 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 859 0.0 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Gene3D G3DSA:1.10.730.10 648 795 2.4E-45 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Pfam PF08264 Anticodon-binding domain of tRNA 701 821 7.0E-17 T 10-03-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 SUPERFAMILY SSF47323 662 859 8.22E-38 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Gene3D G3DSA:3.90.740.10 223 424 7.8E-62 T 10-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 859 23.315 T 10-03-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 SUPERFAMILY SSF50677 226 415 1.15E-57 T 10-03-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 417 572 2.7E-7 T 10-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 619 651 1.2E-6 T 10-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 171 6.2E-26 T 10-03-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS07895 1b3ea4e8263fbf1097dcb22b80304c85 860 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 403 4.0E-79 T 10-03-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Gene3D G3DSA:2.30.38.10 776 853 3.4E-26 T 10-03-2017 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 SUPERFAMILY SSF53474 1050 1291 2.38E-47 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 SMART SM00824 Thioesterase 1069 1245 1.8E-4 T 10-03-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Pfam PF00975 Thioesterase domain 1067 1283 7.4E-50 T 10-03-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Gene3D G3DSA:3.40.50.980 454 621 5.1E-43 T 10-03-2017 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Gene3D G3DSA:1.10.1200.10 966 1047 2.7E-18 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 SUPERFAMILY SSF47336 971 1042 6.02E-12 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 ProSitePatterns PS00455 Putative AMP-binding domain signature. 600 611 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Pfam PF00501 AMP-binding enzyme 462 863 3.4E-96 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 SUPERFAMILY SSF52777 190 426 4.78E-32 T 10-03-2017 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Pfam PF00550 Phosphopantetheine attachment site 980 1040 2.1E-10 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 SMART SM00823 Phosphopantetheine attachment site 977 1046 0.0051 T 10-03-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 SUPERFAMILY SSF52777 9 183 4.56E-31 T 10-03-2017 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Gene3D G3DSA:3.40.50.980 622 775 4.4E-44 T 10-03-2017 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Gene3D G3DSA:3.40.50.1820 1050 1170 1.9E-41 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Gene3D G3DSA:3.40.50.1820 1225 1292 1.9E-41 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Gene3D G3DSA:3.30.300.30 857 964 1.6E-28 T 10-03-2017 RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 482 886 3.2E-127 T 10-03-2017 IPR010071 Amino acid adenylation domain RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1001 1016 - T 10-03-2017 IPR006162 Phosphopantetheine attachment site RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 Pfam PF00668 Condensation domain 2 300 8.1E-74 T 10-03-2017 IPR001242 Condensation domain RG49_RS08205 fa4c841c1dbdbb5132415b305a9b3ffa 1293 SUPERFAMILY SSF56801 436 989 7.85E-148 T 10-03-2017 RG49_RS16505 46878df06908678544228c509871d19f 463 SUPERFAMILY SSF53383 74 462 2.45E-50 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS16505 46878df06908678544228c509871d19f 463 Gene3D G3DSA:3.40.640.10 78 321 6.4E-31 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS16505 46878df06908678544228c509871d19f 463 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 463 257.474 T 10-03-2017 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 RG49_RS16505 46878df06908678544228c509871d19f 463 Pfam PF03841 L-seryl-tRNA selenium transferase 83 451 2.2E-181 T 10-03-2017 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 RG49_RS16505 46878df06908678544228c509871d19f 463 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 10 460 1.8E-190 T 10-03-2017 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 RG49_RS16505 46878df06908678544228c509871d19f 463 Pfam PF12390 Selenocysteine synthase N terminal 9 48 2.1E-9 T 10-03-2017 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 Gene3D G3DSA:3.40.50.920 538 663 5.8E-53 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 Pfam PF02780 Transketolase, C-terminal domain 540 655 6.9E-20 T 10-03-2017 IPR033248 Transketolase, C-terminal domain RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 10-03-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 SMART SM00861 355 525 8.1E-66 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 Gene3D G3DSA:3.40.50.970 327 533 1.7E-80 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 10-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 8.0E-175 T 10-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 SUPERFAMILY SSF52922 533 663 2.49E-44 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 5 663 0.0 T 10-03-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 SUPERFAMILY SSF52518 5 331 2.57E-122 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 Gene3D G3DSA:3.40.50.970 4 320 6.1E-134 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 SUPERFAMILY SSF52518 336 526 4.53E-67 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS20215 dccf3c9edddfd9e490612e563185c9b9 663 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 5.8E-44 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 SUPERFAMILY SSF53067 5 191 6.22E-65 T 10-03-2017 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 PRINTS PR00471 Acetate kinase family signature 199 220 2.3E-47 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 PRINTS PR00471 Acetate kinase family signature 296 309 2.3E-47 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 PRINTS PR00471 Acetate kinase family signature 374 386 2.3E-47 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 PRINTS PR00471 Acetate kinase family signature 318 334 2.3E-47 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 PRINTS PR00471 Acetate kinase family signature 169 182 2.3E-47 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 PRINTS PR00471 Acetate kinase family signature 7 18 2.3E-47 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 Hamap MF_01881 Propionate kinase [tdcD]. 1 402 78.206 T 10-03-2017 IPR024917 Propionate kinase KEGG: 00640+2.7.2.15|MetaCyc: PWY-5437|MetaCyc: PWY-7013 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 PIRSF PIRSF000722 3 397 5.3E-134 T 10-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 Pfam PF00871 Acetokinase family 7 386 8.5E-168 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 Gene3D G3DSA:3.30.420.40 7 200 1.1E-11 T 10-03-2017 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 TIGRFAM TIGR00016 ackA: acetate kinase 4 393 6.3E-173 T 10-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 199 216 - T 10-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 10-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 Hamap MF_00020 Acetate kinase [ackA]. 1 396 163.425 T 10-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 SUPERFAMILY SSF53067 153 392 3.89E-85 T 10-03-2017 RG49_RS19135 d962ca2e62e2633b629c9e0722a22b09 402 Gene3D G3DSA:3.30.420.40 201 391 4.5E-71 T 10-03-2017 RG49_RS21305 e0e711cfc52935cf8f0c4e8d7f7067b3 345 Pfam PF04389 Peptidase family M28 100 330 7.2E-35 T 10-03-2017 IPR007484 Peptidase M28 RG49_RS21305 e0e711cfc52935cf8f0c4e8d7f7067b3 345 SUPERFAMILY SSF53187 42 316 3.14E-37 T 10-03-2017 RG49_RS21305 e0e711cfc52935cf8f0c4e8d7f7067b3 345 Gene3D G3DSA:3.40.630.10 37 344 4.2E-47 T 10-03-2017 RG49_RS25230 9e1ed58de74fd72e49ad29a30acf4ec9 178 Pfam PF02502 Ribose/Galactose Isomerase 5 134 1.2E-32 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS25230 9e1ed58de74fd72e49ad29a30acf4ec9 178 Gene3D G3DSA:3.40.1400.10 2 151 1.6E-37 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS25230 9e1ed58de74fd72e49ad29a30acf4ec9 178 PIRSF PIRSF005384 3 153 1.6E-33 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS25230 9e1ed58de74fd72e49ad29a30acf4ec9 178 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 5 134 3.6E-29 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS25230 9e1ed58de74fd72e49ad29a30acf4ec9 178 SUPERFAMILY SSF89623 2 136 1.03E-32 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Pfam PF00384 Molybdopterin oxidoreductase 119 576 1.5E-113 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 731 758 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Gene3D G3DSA:2.40.40.20 670 814 8.3E-60 T 10-03-2017 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Gene3D G3DSA:3.40.50.740 411 654 2.5E-80 T 10-03-2017 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Gene3D G3DSA:3.40.50.740 121 206 2.5E-80 T 10-03-2017 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 SUPERFAMILY SSF53706 57 697 2.62E-182 T 10-03-2017 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 45 3.7E-4 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 56 116 1.0E-17 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 61 79 - T 10-03-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 SUPERFAMILY SSF50692 641 814 7.91E-42 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 517 534 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 14 814 0.0 T 10-03-2017 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 SMART SM00926 56 116 1.8E-9 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Gene3D G3DSA:3.40.228.10 207 410 1.0E-75 T 10-03-2017 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Pfam PF01568 Molydopterin dinucleotide binding domain 695 806 7.4E-29 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS06265 68b0dd089536b4ce2404d75deec8bb41 814 Gene3D G3DSA:2.20.25.90 54 120 6.3E-18 T 10-03-2017 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 SMART SM00936 292 383 1.8E-33 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 292 383 2.5E-24 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 SUPERFAMILY SSF69189 292 385 7.85E-25 T 10-03-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 5.7E-17 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 131 148 5.7E-17 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 158 171 5.7E-17 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 Gene3D G3DSA:3.40.710.10 37 290 1.1E-91 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 Gene3D G3DSA:2.60.410.10 292 383 4.0E-32 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 SUPERFAMILY SSF56601 10 292 6.71E-76 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS07945 67e71e11a5d766dba6838af555ed17d3 403 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 39 272 2.3E-101 T 10-03-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Gene3D G3DSA:1.10.8.210 150 212 4.0E-23 T 10-03-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Gene3D G3DSA:3.30.950.10 332 456 1.3E-48 T 10-03-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 216 448 5.5E-92 T 10-03-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 296 329 - T 10-03-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 SUPERFAMILY SSF75615 114 207 1.96E-26 T 10-03-2017 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 SUPERFAMILY SSF51735 2 112 4.44E-27 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 221 235 - T 10-03-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Pfam PF10414 Sirohaem synthase dimerisation region 150 207 3.1E-18 T 10-03-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Hamap MF_01646 Siroheme synthase [cysG]. 1 457 51.134 T 10-03-2017 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Gene3D G3DSA:3.40.50.720 2 112 1.1E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 218 426 1.6E-50 T 10-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Pfam PF13241 Putative NAD(P)-binding 6 115 7.1E-26 T 10-03-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 SUPERFAMILY SSF53790 215 456 7.33E-80 T 10-03-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 7.0E-9 T 10-03-2017 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 PIRSF PIRSF036426 1 457 7.1E-206 T 10-03-2017 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Gene3D G3DSA:3.30.160.110 113 148 1.4E-19 T 10-03-2017 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 204 1.6E-70 T 10-03-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 RG49_RS17750 a46d87f6c386033fc81e0fb9256d1408 457 Gene3D G3DSA:3.40.1010.10 215 331 8.5E-46 T 10-03-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 RG49_RS05800 26b060829f833842c9fcbf35407fd70f 726 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 535 659 2.1E-9 T 10-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain RG49_RS05800 26b060829f833842c9fcbf35407fd70f 726 SUPERFAMILY SSF52540 532 710 1.33E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05800 26b060829f833842c9fcbf35407fd70f 726 Pfam PF02706 Chain length determinant protein 16 252 3.1E-52 T 10-03-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 RG49_RS05800 26b060829f833842c9fcbf35407fd70f 726 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 513 719 2.1E-48 T 10-03-2017 IPR005702 Exopolysaccharide synthesis protein GO:0045226 RG49_RS05800 26b060829f833842c9fcbf35407fd70f 726 Pfam PF13807 G-rich domain on putative tyrosine kinase 367 448 3.5E-33 T 10-03-2017 IPR032807 Tyrosine kinase, G-rich domain RG49_RS05800 26b060829f833842c9fcbf35407fd70f 726 Gene3D G3DSA:3.40.50.300 532 708 1.0E-30 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02325 30c1bf30be6b2c82cba5ee57e814c3c3 84 Pfam PF07041 Protein of unknown function (DUF1327) 1 82 2.4E-43 T 10-03-2017 IPR009759 Bacteriophage ES18, Gp24 RG49_RS13520 5013260ed68b5179424d73d5a0235257 252 TIGRFAM TIGR03307 PhnP: phosphonate metabolism protein PhnP 3 248 4.5E-128 T 10-03-2017 IPR017693 Phosphonate metabolism protein PhnP GO:0008081|GO:0019700 KEGG: 00440+3.1.4.55 RG49_RS13520 5013260ed68b5179424d73d5a0235257 252 Pfam PF12706 Beta-lactamase superfamily domain 70 223 3.6E-14 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS13520 5013260ed68b5179424d73d5a0235257 252 Gene3D G3DSA:3.60.15.10 2 251 1.0E-61 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS13520 5013260ed68b5179424d73d5a0235257 252 SUPERFAMILY SSF56281 5 251 2.75E-33 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS18795 28747e1f7b03d688e1e142c0e13a7a19 152 SUPERFAMILY SSF74942 85 152 3.53E-17 T 10-03-2017 IPR028998 Ribosome maturation factor RimP, C-terminal RG49_RS18795 28747e1f7b03d688e1e142c0e13a7a19 152 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 8 152 24.786 T 10-03-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 RG49_RS18795 28747e1f7b03d688e1e142c0e13a7a19 152 Pfam PF02576 Putative ribosome maturation factor RimP 14 148 7.1E-49 T 10-03-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 RG49_RS18795 28747e1f7b03d688e1e142c0e13a7a19 152 Gene3D G3DSA:2.30.30.180 89 149 1.4E-13 T 10-03-2017 IPR028998 Ribosome maturation factor RimP, C-terminal RG49_RS18795 28747e1f7b03d688e1e142c0e13a7a19 152 Gene3D G3DSA:3.30.300.70 4 81 2.2E-33 T 10-03-2017 IPR028989 Ribosome maturation factor RimP, N-terminal RG49_RS18795 28747e1f7b03d688e1e142c0e13a7a19 152 SUPERFAMILY SSF75420 4 84 3.53E-25 T 10-03-2017 IPR028989 Ribosome maturation factor RimP, N-terminal RG49_RS21650 f4b7687a49e4061c8c65ddda7b06c132 518 Pfam PF04262 Glutamate-cysteine ligase 9 380 8.9E-172 T 10-03-2017 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 RG49_RS21650 f4b7687a49e4061c8c65ddda7b06c132 518 SUPERFAMILY SSF55931 4 514 9.81E-203 T 10-03-2017 RG49_RS21650 f4b7687a49e4061c8c65ddda7b06c132 518 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 518 227.977 T 10-03-2017 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 RG49_RS21650 f4b7687a49e4061c8c65ddda7b06c132 518 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 6 517 1.1E-276 T 10-03-2017 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 RG49_RS22620 5e2777069dc3cfa1cc66e785831ad0dd 63 Pfam PF11119 Protein of unknown function (DUF2633) 9 62 1.1E-30 T 10-03-2017 IPR022576 Protein of unknown function DUF2633 RG49_RS22620 5e2777069dc3cfa1cc66e785831ad0dd 63 ProDom PD053432 MEMBRANE TRANSMEMBRANE YFGG INNER EXPORTED Y1396 PRECURSOR SIGNAL 1 63 2.0E-29 T 10-03-2017 IPR022576 Protein of unknown function DUF2633 RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 209 240 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 SMART SM00922 128 259 6.6E-14 T 10-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 SUPERFAMILY SSF54826 1 112 8.06E-34 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 Gene3D G3DSA:3.30.390.10 1 119 5.5E-52 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 Pfam PF13378 Enolase C-terminal domain-like 194 379 4.0E-42 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 SUPERFAMILY SSF51604 98 388 6.55E-79 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 110 3.4E-35 T 10-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS02175 5092bc15a4b7ef6e23fc0d243a499af4 404 Gene3D G3DSA:3.20.20.120 120 367 1.7E-86 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 Gene3D G3DSA:3.30.870.10 254 395 1.0E-15 T 10-03-2017 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 Gene3D G3DSA:3.30.870.10 26 153 5.9E-16 T 10-03-2017 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 Pfam PF13091 PLD-like domain 40 153 2.1E-6 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 Pfam PF13091 PLD-like domain 257 404 2.4E-23 T 10-03-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 SMART SM00155 133 159 0.012 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 SMART SM00155 352 379 2.9E-5 T 10-03-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 SUPERFAMILY SSF56024 253 395 8.48E-19 T 10-03-2017 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 SUPERFAMILY SSF56024 9 208 1.32E-27 T 10-03-2017 RG49_RS22110 733b113d00017964d4c90f6e6325c31c 451 PIRSF PIRSF000850 1 451 2.1E-269 T 10-03-2017 IPR016270 Phospholipase D, phosphatidylserine synthase type GO:0008654|GO:0016780 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|Reactome: R-HSA-1483148 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 SUPERFAMILY SSF56053 1 82 9.55E-24 T 10-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.3E-34 T 10-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.3E-34 T 10-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.3E-34 T 10-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.551 T 10-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 Pfam PF00347 Ribosomal protein L6 90 164 6.9E-19 T 10-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 Pfam PF00347 Ribosomal protein L6 11 82 1.0E-18 T 10-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 SUPERFAMILY SSF56053 83 177 1.1E-35 T 10-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 Gene3D G3DSA:3.90.930.12 83 177 2.4E-40 T 10-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 Gene3D G3DSA:3.90.930.12 2 82 7.5E-29 T 10-03-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 10-03-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 PIRSF PIRSF002162 1 177 6.4E-44 T 10-03-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18075 fca3d6d18d398b02d8ecfea1adc85eee 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 5.5E-73 T 10-03-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 Gene3D G3DSA:2.60.120.10 35 96 2.6E-6 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 Gene3D G3DSA:1.10.10.60 192 243 8.2E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 286 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 SMART SM00342 207 290 1.1E-27 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 1.3E-5 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 1.3E-5 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 Pfam PF12833 Helix-turn-helix domain 214 291 8.1E-19 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 SUPERFAMILY SSF51182 33 105 6.17E-7 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 Gene3D G3DSA:1.10.10.60 244 292 4.3E-17 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 SUPERFAMILY SSF46689 243 291 8.51E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13365 0544ae6ac6e7dd6ca5dc2aa8872eecc9 302 SUPERFAMILY SSF47454 129 186 6.8E-12 T 10-03-2017 IPR008917 Transcription factor, Skn-1-like, DNA-binding domain GO:0003677|GO:0006355 RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 SMART SM00316 37 119 9.5E-12 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 Pfam PF00575 S1 RNA binding domain 36 118 3.5E-16 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 Pfam PF10150 Ribonuclease E/G family 121 391 1.9E-93 T 10-03-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 425 6.2E-172 T 10-03-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 Pfam PF12111 Polyribonucleotide phosphorylase C terminal 1022 1058 1.8E-16 T 10-03-2017 IPR021968 Polyribonucleotide phosphorylase C-terminal RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 Hamap MF_00970 Ribonuclease E [rne]. 1 1047 41.079 T 10-03-2017 IPR028878 Ribonuclease E GO:0006396|GO:0008995 RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 SUPERFAMILY SSF50249 40 124 1.82E-20 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS05225 7d41386f76781db56a66fb79e5da3767 1061 Gene3D G3DSA:2.40.50.140 31 124 8.1E-36 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06410 ae82b821f7fcec91ba5037a3caff82b5 333 PIRSF PIRSF017617 1 333 1.5E-129 T 10-03-2017 IPR023603 Threonine aldolase RG49_RS06410 ae82b821f7fcec91ba5037a3caff82b5 333 Pfam PF01212 Beta-eliminating lyase 3 282 2.7E-96 T 10-03-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 RG49_RS06410 ae82b821f7fcec91ba5037a3caff82b5 333 Gene3D G3DSA:3.40.640.10 1 245 1.4E-87 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS06410 ae82b821f7fcec91ba5037a3caff82b5 333 SUPERFAMILY SSF53383 1 331 2.02E-113 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS06410 ae82b821f7fcec91ba5037a3caff82b5 333 Gene3D G3DSA:3.90.1150.10 246 332 3.9E-25 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS05405 47528fe39cf0e25a71a2c6cae0e1ba55 847 Pfam PF00535 Glycosyl transferase family 2 246 428 3.7E-23 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS05405 47528fe39cf0e25a71a2c6cae0e1ba55 847 SUPERFAMILY SSF53448 244 532 1.13E-25 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS05405 47528fe39cf0e25a71a2c6cae0e1ba55 847 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 64 745 52.448 T 10-03-2017 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 Gene3D G3DSA:3.20.20.70 4 292 1.8E-87 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 10-03-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 Hamap MF_01237 N-acetylneuraminate lyase [nanA]. 5 294 52.009 T 10-03-2017 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 PIRSF PIRSF001365 1 297 5.3E-85 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 41 58 - T 10-03-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 TIGRFAM TIGR00683 nanA: N-acetylneuraminate lyase 5 297 8.6E-173 T 10-03-2017 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 SMART SM01130 4 293 7.5E-88 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 SUPERFAMILY SSF51569 5 291 6.7E-82 T 10-03-2017 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 Pfam PF00701 Dihydrodipicolinate synthetase family 5 291 3.6E-113 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 1.4E-21 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 1.4E-21 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 1.4E-21 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS18500 8c6264609850a1927d3dae67989bc9cb 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 1.4E-21 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS10495 ff2ef5f97bb20bfe40b98ba099e6837f 185 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 96 112 - T 10-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 RG49_RS10495 ff2ef5f97bb20bfe40b98ba099e6837f 185 Pfam PF00472 RF-1 domain 87 163 5.9E-23 T 10-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 RG49_RS10495 ff2ef5f97bb20bfe40b98ba099e6837f 185 TIGRFAM TIGR03072 release_prfH: putative peptide chain release factor H 13 182 1.8E-83 T 10-03-2017 IPR017509 Putative peptide chain release factor H RG49_RS10495 ff2ef5f97bb20bfe40b98ba099e6837f 185 Gene3D G3DSA:3.30.160.20 88 154 3.7E-26 T 10-03-2017 IPR014720 Double-stranded RNA-binding domain RG49_RS10495 ff2ef5f97bb20bfe40b98ba099e6837f 185 SUPERFAMILY SSF75620 13 177 6.41E-41 T 10-03-2017 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 SMART SM00363 18 83 9.1E-14 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 Gene3D G3DSA:3.10.290.10 18 68 5.7E-14 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 Pfam PF00849 RNA pseudouridylate synthase 92 242 2.0E-31 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 Pfam PF01479 S4 domain 18 65 7.2E-13 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 SUPERFAMILY SSF55174 17 69 6.39E-12 T 10-03-2017 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 10-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 SUPERFAMILY SSF55120 77 323 3.7E-79 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS22055 007e91ed8c72886d7f9fd02da8969de7 326 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 313 1.9E-111 T 10-03-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS15120 4f1d2b86593d0827cac0b1892695e408 254 Pfam PF09992 Phosphodiester glycosidase 84 235 2.9E-17 T 10-03-2017 IPR018711 Phosphodiester glycosidase RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Gene3D G3DSA:3.30.300.20 278 346 5.3E-26 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Gene3D G3DSA:3.30.300.20 199 277 2.4E-34 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 SUPERFAMILY SSF47794 355 414 3.61E-17 T 10-03-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 SUPERFAMILY SSF69705 1 126 1.96E-41 T 10-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 SUPERFAMILY SSF50249 132 199 2.03E-17 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 SUPERFAMILY SSF54814 201 278 3.73E-29 T 10-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Gene3D G3DSA:3.30.1480.10 1 124 1.0E-46 T 10-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Pfam PF08529 NusA N-terminal domain 4 123 1.6E-37 T 10-03-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Gene3D G3DSA:1.10.150.20 431 492 4.4E-25 T 10-03-2017 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Pfam PF00575 S1 RNA binding domain 134 195 1.6E-4 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Pfam PF13184 NusA-like KH domain 230 297 2.1E-27 T 10-03-2017 IPR025249 KH domain, NusA-like GO:0003723 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Gene3D G3DSA:1.10.150.20 357 414 4.1E-23 T 10-03-2017 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 SUPERFAMILY SSF47794 429 492 9.58E-18 T 10-03-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Gene3D G3DSA:2.40.50.140 128 197 3.0E-24 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 342 1.7E-130 T 10-03-2017 IPR010213 Transcription termination factor NusA GO:0003723 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 410 29.272 T 10-03-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 SUPERFAMILY SSF54814 279 343 3.18E-15 T 10-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 SMART SM00316 133 200 7.7E-9 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 440 489 1.2E-18 T 10-03-2017 IPR010214 Transcription termination factor NusA, C-terminal duplication RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 365 414 4.0E-21 T 10-03-2017 IPR010214 Transcription termination factor NusA, C-terminal duplication RG49_RS18800 3e03ed8d35ddb858f919fa9b04e5a497 495 Pfam PF14520 Helix-hairpin-helix domain 432 486 2.2E-9 T 10-03-2017 RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 58.63 T 10-03-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 Gene3D G3DSA:1.10.166.10 1 70 5.3E-33 T 10-03-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 6.1E-13 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 SUPERFAMILY SSF51161 1 256 8.46E-81 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 Gene3D G3DSA:2.160.10.10 89 255 1.6E-64 T 10-03-2017 RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3 273 1.6E-165 T 10-03-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 166 0.0019 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10995 456634840ecc8c243e1ffa2773ca7012 274 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 4.9E-26 T 10-03-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 10-03-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 132 5.4E-61 T 10-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 133 31.385 T 10-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 102 8.7E-15 T 10-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 8.7E-15 T 10-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 92 8.7E-15 T 10-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 4 130 2.7E-46 T 10-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 Gene3D G3DSA:1.20.5.220 120 129 7.2E-4 T 10-03-2017 IPR029027 Single alpha-helix domain Reactome: R-HSA-611105 RG49_RS18150 9a0b9a6c80c111b01765f49bf696bf99 136 SUPERFAMILY SSF81330 12 126 9.94E-37 T 10-03-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 RG49_RS21320 e76736719b951c91dc283a3fd5205c58 201 Gene3D G3DSA:3.40.50.300 6 200 2.0E-88 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21320 e76736719b951c91dc283a3fd5205c58 201 Pfam PF01583 Adenylylsulphate kinase 27 179 9.8E-73 T 10-03-2017 RG49_RS21320 e76736719b951c91dc283a3fd5205c58 201 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 10 193 1.4E-89 T 10-03-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 RG49_RS21320 e76736719b951c91dc283a3fd5205c58 201 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 26 197 38.735 T 10-03-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 RG49_RS21320 e76736719b951c91dc283a3fd5205c58 201 SUPERFAMILY SSF52540 24 194 1.65E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13075 3cf4551f131dd653f0227023b6c1c1fb 153 Gene3D G3DSA:3.40.50.300 4 150 6.5E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13075 3cf4551f131dd653f0227023b6c1c1fb 153 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 140 1.1E-59 T 10-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 RG49_RS13075 3cf4551f131dd653f0227023b6c1c1fb 153 SUPERFAMILY SSF52540 29 131 9.25E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13075 3cf4551f131dd653f0227023b6c1c1fb 153 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 133 2.2E-42 T 10-03-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 Gene3D G3DSA:1.10.287.40 1 104 2.4E-29 T 10-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 SUPERFAMILY SSF46589 1 112 1.41E-32 T 10-03-2017 IPR010978 tRNA-binding arm GO:0000166 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 3.9E-34 T 10-03-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 PRINTS PR00981 Seryl-tRNA synthetase signature 282 295 8.6E-34 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 PRINTS PR00981 Seryl-tRNA synthetase signature 339 355 8.6E-34 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 PRINTS PR00981 Seryl-tRNA synthetase signature 270 282 8.6E-34 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 PRINTS PR00981 Seryl-tRNA synthetase signature 322 335 8.6E-34 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 8.6E-34 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 PIRSF PIRSF001529 1 430 6.3E-186 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 423 2.1E-185 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 428 41.817 T 10-03-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 Gene3D G3DSA:3.30.930.10 105 427 1.5E-142 T 10-03-2017 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 SUPERFAMILY SSF55681 116 424 1.11E-99 T 10-03-2017 RG49_RS06270 5428c38a6a43a1cd085e19ad69956708 430 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 228 406 8.7E-36 T 10-03-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS11170 8d83aa5365fd6e7bbacd96e7ed4fbebd 264 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 258 7.7E-106 T 10-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 RG49_RS11170 8d83aa5365fd6e7bbacd96e7ed4fbebd 264 Gene3D G3DSA:3.20.20.60 1 264 8.7E-111 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS11170 8d83aa5365fd6e7bbacd96e7ed4fbebd 264 PIRSF PIRSF000388 1 264 1.2E-97 T 10-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 RG49_RS11170 8d83aa5365fd6e7bbacd96e7ed4fbebd 264 SUPERFAMILY SSF51621 4 263 1.67E-104 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS11170 8d83aa5365fd6e7bbacd96e7ed4fbebd 264 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 263 42.096 T 10-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 RG49_RS11170 8d83aa5365fd6e7bbacd96e7ed4fbebd 264 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 264 1.7E-131 T 10-03-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 RG49_RS01490 2a5980ca6a30a5c92f59564c51961911 478 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 2 450 5.9E-160 T 10-03-2017 IPR003846 Uncharacterised protein family UPF0061 RG49_RS01490 2a5980ca6a30a5c92f59564c51961911 478 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 1 464 46.718 T 10-03-2017 IPR003846 Uncharacterised protein family UPF0061 RG49_RS07150 7441f2eeb82631cd04194e5dd4597e39 384 SUPERFAMILY SSF53383 3 380 2.96E-112 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS07150 7441f2eeb82631cd04194e5dd4597e39 384 Gene3D G3DSA:3.90.1150.10 270 381 8.0E-36 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS07150 7441f2eeb82631cd04194e5dd4597e39 384 Gene3D G3DSA:3.40.640.10 58 269 1.7E-84 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS07150 7441f2eeb82631cd04194e5dd4597e39 384 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 3 384 51.0 T 10-03-2017 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 RG49_RS07150 7441f2eeb82631cd04194e5dd4597e39 384 Pfam PF00155 Aminotransferase class I and II 40 380 1.5E-69 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS07150 7441f2eeb82631cd04194e5dd4597e39 384 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 10-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 RG49_RS07150 7441f2eeb82631cd04194e5dd4597e39 384 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 20 381 8.1E-150 T 10-03-2017 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 RG49_RS05970 1e8d63b5acfb729180a73b5e0eda4460 417 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 1 408 7.0E-200 T 10-03-2017 IPR005219 Conserved hypothetical protein CHP00155 RG49_RS05970 1e8d63b5acfb729180a73b5e0eda4460 417 Pfam PF04403 Paraquat-inducible protein A 253 408 6.6E-54 T 10-03-2017 IPR007498 Paraquat-inducible protein A RG49_RS05970 1e8d63b5acfb729180a73b5e0eda4460 417 Pfam PF04403 Paraquat-inducible protein A 49 200 1.1E-39 T 10-03-2017 IPR007498 Paraquat-inducible protein A RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 Gene3D G3DSA:3.40.50.720 6 252 6.6E-82 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 1.9E-56 T 10-03-2017 RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.6E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.6E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.6E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.6E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.6E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.6E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 6 253 3.1E-138 T 10-03-2017 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.12+1.1.1.127|MetaCyc: PWY-5515|MetaCyc: PWY-6507|MetaCyc: PWY-7562 RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 SUPERFAMILY SSF51735 9 252 1.13E-76 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.7E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.7E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS20815 c2394212a6c13b653747deb8690438ef 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.7E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 Pfam PF05343 M42 glutamyl aminopeptidase 43 333 1.0E-101 T 10-03-2017 IPR008007 Peptidase M42 RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 PIRSF PIRSF001123 1 352 4.0E-138 T 10-03-2017 IPR008007 Peptidase M42 RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 SUPERFAMILY SSF53187 167 347 1.74E-58 T 10-03-2017 RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 SUPERFAMILY SSF53187 3 76 1.74E-58 T 10-03-2017 RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 Gene3D G3DSA:2.40.30.40 71 157 2.5E-36 T 10-03-2017 IPR023367 Peptidase M42, domain 2 RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 Gene3D G3DSA:3.40.630.10 167 355 7.9E-78 T 10-03-2017 RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 Gene3D G3DSA:3.40.630.10 3 70 7.9E-78 T 10-03-2017 RG49_RS14665 79e2d7e60bec3d141f88daa6ec967240 356 SUPERFAMILY SSF101821 66 175 5.8E-32 T 10-03-2017 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 SMART SM01230 102 379 5.2E-152 T 10-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 2.4E-140 T 10-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 SUPERFAMILY SSF54368 3 99 3.01E-36 T 10-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 10-03-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 SUPERFAMILY SSF55931 102 468 3.83E-139 T 10-03-2017 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 10-03-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 Gene3D G3DSA:3.30.590.10 106 455 1.4E-140 T 10-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 Gene3D G3DSA:3.10.20.70 3 105 5.0E-40 T 10-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 4 468 6.1E-221 T 10-03-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 10-03-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 RG49_RS14830 db66e6214ba9e9524ecbc161094c8675 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 6.8E-32 T 10-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 Gene3D G3DSA:1.10.10.10 1 84 2.7E-28 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.6E-21 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 SUPERFAMILY SSF53850 89 295 4.5E-47 T 10-03-2017 RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 Pfam PF03466 LysR substrate binding domain 89 293 5.4E-54 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 SUPERFAMILY SSF46785 1 86 9.99E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 Gene3D G3DSA:3.40.190.10 90 175 2.1E-18 T 10-03-2017 RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 Gene3D G3DSA:3.40.190.10 176 267 2.0E-37 T 10-03-2017 RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS14305 01f7ef453121c0bb818ead6a5da9a2b6 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19580 b18f416701102b3c46e36034fc406489 209 SUPERFAMILY SSF55811 6 208 1.14E-50 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS19580 b18f416701102b3c46e36034fc406489 209 Gene3D G3DSA:3.90.79.10 11 208 1.1E-56 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS19580 b18f416701102b3c46e36034fc406489 209 Pfam PF00293 NUDIX domain 59 179 1.4E-11 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS19580 b18f416701102b3c46e36034fc406489 209 ProSitePatterns PS00893 Nudix box signature. 97 118 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS19580 b18f416701102b3c46e36034fc406489 209 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 14 199 2.6E-85 T 10-03-2017 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 RG49_RS02915 7d12093c42424e22048e33966d1dd5ad 308 SMART SM00382 41 220 6.2E-20 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS02915 7d12093c42424e22048e33966d1dd5ad 308 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 220 305 1.3E-19 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS02915 7d12093c42424e22048e33966d1dd5ad 308 SUPERFAMILY SSF52540 6 241 3.59E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02915 7d12093c42424e22048e33966d1dd5ad 308 Gene3D G3DSA:3.40.50.300 3 255 8.2E-76 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02915 7d12093c42424e22048e33966d1dd5ad 308 Pfam PF00005 ABC transporter 33 171 7.8E-27 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS02915 7d12093c42424e22048e33966d1dd5ad 308 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 222 287 1.6E-17 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS02915 7d12093c42424e22048e33966d1dd5ad 308 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 Gene3D G3DSA:3.40.50.620 2 68 4.7E-54 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 Gene3D G3DSA:3.40.50.620 181 231 4.7E-54 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 SUPERFAMILY SSF52374 3 298 4.56E-114 T 10-03-2017 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 465 1.3E-212 T 10-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 Gene3D G3DSA:1.10.1160.10 233 314 1.2E-36 T 10-03-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 305 1.1E-124 T 10-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 179 189 5.9E-28 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 5.9E-28 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 203 5.9E-28 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 5.9E-28 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 5.9E-28 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 Gene3D G3DSA:3.90.800.10 69 180 1.1E-39 T 10-03-2017 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 Gene3D G3DSA:1.10.10.350 363 461 8.9E-32 T 10-03-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 SUPERFAMILY SSF48163 299 461 4.05E-46 T 10-03-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS23145 3823599bbfe6a544c24c6b0b0820909c 471 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 3 461 34.152 T 10-03-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 RG49_RS14510 438a615829ba5eaaf7a6b39401811d6e 142 SUPERFAMILY SSF52402 3 138 8.37E-23 T 10-03-2017 RG49_RS14510 438a615829ba5eaaf7a6b39401811d6e 142 Pfam PF00582 Universal stress protein family 3 137 2.6E-19 T 10-03-2017 IPR006016 UspA GO:0006950 RG49_RS14510 438a615829ba5eaaf7a6b39401811d6e 142 PIRSF PIRSF006276 1 141 2.6E-44 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS14510 438a615829ba5eaaf7a6b39401811d6e 142 Gene3D G3DSA:3.40.50.620 3 138 2.0E-22 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS00975 e48d1c1f351c266723f9809664d91861 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 2 358 1.5E-170 T 10-03-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 RG49_RS00975 e48d1c1f351c266723f9809664d91861 361 SMART SM01329 6 355 1.4E-179 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS00975 e48d1c1f351c266723f9809664d91861 361 SUPERFAMILY SSF53659 1 359 1.34E-118 T 10-03-2017 RG49_RS00975 e48d1c1f351c266723f9809664d91861 361 Gene3D G3DSA:3.40.718.10 5 348 4.1E-120 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS00975 e48d1c1f351c266723f9809664d91861 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 355 2.6E-86 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS00975 e48d1c1f351c266723f9809664d91861 361 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 10-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 RG49_RS21915 1505cfc9206b7408efca474ce90cb87a 602 SUPERFAMILY SSF52540 253 389 2.0E-30 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21915 1505cfc9206b7408efca474ce90cb87a 602 SUPERFAMILY SSF52540 35 188 2.0E-30 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21915 1505cfc9206b7408efca474ce90cb87a 602 Pfam PF00271 Helicase conserved C-terminal domain 275 379 2.1E-7 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS21915 1505cfc9206b7408efca474ce90cb87a 602 Pfam PF04851 Type III restriction enzyme, res subunit 13 186 4.6E-26 T 10-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 RG49_RS21915 1505cfc9206b7408efca474ce90cb87a 602 SMART SM00487 10 215 5.6E-16 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS21915 1505cfc9206b7408efca474ce90cb87a 602 Gene3D G3DSA:3.40.50.300 12 190 3.6E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21915 1505cfc9206b7408efca474ce90cb87a 602 Gene3D G3DSA:3.40.50.300 269 402 1.2E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 247 273 3.6E-55 T 10-03-2017 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 110 130 3.6E-55 T 10-03-2017 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 157 178 3.6E-55 T 10-03-2017 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 82 107 3.6E-55 T 10-03-2017 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 225 246 3.6E-55 T 10-03-2017 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 3.6E-55 T 10-03-2017 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 315 327 3.6E-55 T 10-03-2017 RG49_RS23700 8186956538afccc908488f644a376133 613 Pfam PF00361 Proton-conducting membrane transporter 133 425 2.6E-99 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23700 8186956538afccc908488f644a376133 613 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 121 9.9E-24 T 10-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23700 8186956538afccc908488f644a376133 613 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 610 2.5E-239 T 10-03-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 58 82 1.9E-11 T 10-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 84 104 1.9E-11 T 10-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 265 287 1.9E-11 T 10-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 RG49_RS23700 8186956538afccc908488f644a376133 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 417 439 1.9E-11 T 10-03-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 10-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 SUPERFAMILY SSF48498 82 191 8.23E-18 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 Gene3D G3DSA:1.10.357.10 1 191 2.0E-45 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 192 8.8E-81 T 10-03-2017 IPR017757 Transcriptional repressor BetI RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.8E-14 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 SUPERFAMILY SSF46689 6 79 3.85E-17 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.3E-6 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.3E-6 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 Pfam PF13977 Bacterial transcriptional repressor 85 192 3.7E-30 T 10-03-2017 RG49_RS09615 2115970d6fc6e17c960a5dd6f7042705 195 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 195 103.08 T 10-03-2017 IPR017757 Transcriptional repressor BetI RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 394 1.2E-192 T 10-03-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 Gene3D G3DSA:3.10.580.10 272 395 6.7E-22 T 10-03-2017 RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 Pfam PF00005 ABC transporter 45 192 2.1E-34 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 Gene3D G3DSA:3.40.50.300 41 264 1.6E-80 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 SMART SM00382 53 242 9.1E-19 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 SUPERFAMILY SSF54631 276 394 7.93E-12 T 10-03-2017 RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 SUPERFAMILY SSF52540 43 270 3.39E-77 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 Pfam PF00571 CBS domain 347 393 1.3E-5 T 10-03-2017 IPR000644 CBS domain RG49_RS21700 e726725ff59b4c2e0e1293fc2ea83fbb 400 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS10075 4b7f742843b24a8c315cd448cb4a47f1 383 Pfam PF13936 Helix-turn-helix domain 58 98 5.0E-18 T 10-03-2017 IPR025246 Transposase IS30-like HTH domain RG49_RS10075 4b7f742843b24a8c315cd448cb4a47f1 383 SUPERFAMILY SSF53098 229 375 9.67E-26 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10075 4b7f742843b24a8c315cd448cb4a47f1 383 Gene3D G3DSA:3.30.420.10 231 375 6.2E-12 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10075 4b7f742843b24a8c315cd448cb4a47f1 383 ProSitePatterns PS01043 Transposases, IS30 family, signature. 323 339 - T 10-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 RG49_RS10075 4b7f742843b24a8c315cd448cb4a47f1 383 Pfam PF00665 Integrase core domain 230 336 2.3E-14 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS09965 5afb247ac0ebb8e282c5e7f047e9a9c4 432 ProSitePatterns PS01007 Transposases, Mutator family, signature. 232 256 - T 10-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 RG49_RS09965 5afb247ac0ebb8e282c5e7f047e9a9c4 432 Pfam PF00872 Transposase, Mutator family 16 377 3.0E-108 T 10-03-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 268 1.1E-30 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 SMART SM00062 47 269 6.3E-51 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 Pfam PF01464 Transglycosylase SLT domain 297 402 3.2E-22 T 10-03-2017 IPR008258 Transglycosylase SLT domain 1 RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 5 473 47.515 T 10-03-2017 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 Gene3D G3DSA:3.40.190.10 41 129 6.6E-16 T 10-03-2017 RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 Gene3D G3DSA:3.40.190.10 227 267 6.6E-16 T 10-03-2017 RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 SUPERFAMILY SSF53955 245 398 9.01E-34 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 SUPERFAMILY SSF53955 433 441 9.01E-34 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 Gene3D G3DSA:1.10.530.10 288 462 2.0E-35 T 10-03-2017 RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 SUPERFAMILY SSF53850 40 268 3.68E-35 T 10-03-2017 RG49_RS22270 c3fa5b0f2d55fae911e766460dc3b356 518 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 310 338 - T 10-03-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 RG49_RS11335 63ecd4b41556f1bad2ce79765d13a1f8 400 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 158 186 - T 10-03-2017 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 RG49_RS11335 63ecd4b41556f1bad2ce79765d13a1f8 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 361 375 2.6E-14 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS11335 63ecd4b41556f1bad2ce79765d13a1f8 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 158 186 2.6E-14 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS11335 63ecd4b41556f1bad2ce79765d13a1f8 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 377 396 2.6E-14 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS11335 63ecd4b41556f1bad2ce79765d13a1f8 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 59 71 2.6E-14 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS11335 63ecd4b41556f1bad2ce79765d13a1f8 400 Pfam PF00482 Type II secretion system (T2SS), protein F 269 388 1.1E-24 T 10-03-2017 IPR018076 Type II secretion system F domain RG49_RS11335 63ecd4b41556f1bad2ce79765d13a1f8 400 Pfam PF00482 Type II secretion system (T2SS), protein F 64 186 4.1E-29 T 10-03-2017 IPR018076 Type II secretion system F domain RG49_RS24205 36e730ae4c428e9a0ba546ba875139de 75 SUPERFAMILY SSF158651 1 75 9.29E-33 T 10-03-2017 RG49_RS24205 36e730ae4c428e9a0ba546ba875139de 75 Pfam PF07208 Protein of unknown function (DUF1414) 26 69 5.8E-25 T 10-03-2017 IPR009857 Uncharacterised protein family UPF0352 RG49_RS24205 36e730ae4c428e9a0ba546ba875139de 75 Gene3D G3DSA:1.10.3390.10 1 75 2.0E-39 T 10-03-2017 IPR023202 YejL-like domain RG49_RS24205 36e730ae4c428e9a0ba546ba875139de 75 ProDom PD027794 UPF0352 YEJL NTHI1007 CPS_2611 VF1649 VV1166 HD1515 VP2129 YPO1261/Y2923/YP0880 ECA2748 1 69 2.0E-33 T 10-03-2017 IPR009857 Uncharacterised protein family UPF0352 RG49_RS24205 36e730ae4c428e9a0ba546ba875139de 75 Hamap MF_00816 UPF0352 protein YejL [yejL]. 1 71 25.006 T 10-03-2017 IPR009857 Uncharacterised protein family UPF0352 RG49_RS24205 36e730ae4c428e9a0ba546ba875139de 75 PIRSF PIRSF006188 1 72 5.0E-39 T 10-03-2017 IPR009857 Uncharacterised protein family UPF0352 RG49_RS23835 0af5108ce704bda74a7ea408bbdd0b90 200 SUPERFAMILY SSF53254 56 180 7.07E-16 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS23835 0af5108ce704bda74a7ea408bbdd0b90 200 Gene3D G3DSA:3.40.50.1240 56 167 4.4E-10 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS23835 0af5108ce704bda74a7ea408bbdd0b90 200 PIRSF PIRSF011416 1 200 4.9E-89 T 10-03-2017 IPR011310 Lipopolysaccharide core heptose(II)-phosphate phosphatase GO:0016791 RG49_RS23835 0af5108ce704bda74a7ea408bbdd0b90 200 Hamap MF_01868 Lipopolysaccharide core heptose(II)-phosphate phosphatase [ais]. 1 200 62.16 T 10-03-2017 IPR011310 Lipopolysaccharide core heptose(II)-phosphate phosphatase GO:0016791 RG49_RS23835 0af5108ce704bda74a7ea408bbdd0b90 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 56 129 9.7E-6 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 473 4.9E-162 T 10-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 454 1.7E-201 T 10-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 Pfam PF00571 CBS domain 95 140 5.3E-9 T 10-03-2017 IPR000644 CBS domain RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 Pfam PF00571 CBS domain 153 202 1.7E-4 T 10-03-2017 IPR000644 CBS domain RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 SMART SM01240 7 473 0.0 T 10-03-2017 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 SMART SM00116 96 144 2.9E-11 T 10-03-2017 IPR000644 CBS domain RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 SMART SM00116 158 206 1.9E-8 T 10-03-2017 IPR000644 CBS domain RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 SUPERFAMILY SSF54631 94 203 1.11E-24 T 10-03-2017 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 295 307 - T 10-03-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 SUPERFAMILY SSF51412 217 477 1.31E-127 T 10-03-2017 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 SUPERFAMILY SSF51412 1 90 1.31E-127 T 10-03-2017 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 PIRSF PIRSF000130 1 487 1.3E-197 T 10-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 486 85.506 T 10-03-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 RG49_RS22530 116bddd68b8f96de06d9da6d574d1a85 488 Gene3D G3DSA:3.20.20.70 2 485 1.3E-194 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 10-03-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 1.3E-39 T 10-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 Pfam PF00467 KOW motif 8 37 7.6E-5 T 10-03-2017 IPR005824 KOW RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 103 1.6E-23 T 10-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 SUPERFAMILY SSF50104 4 100 3.19E-33 T 10-03-2017 IPR008991 Translation protein SH3-like domain RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 20.157 T 10-03-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 Gene3D G3DSA:2.30.30.30 3 92 3.5E-22 T 10-03-2017 IPR014722 Ribosomal protein L2 domain 2 RG49_RS18055 17619cacd8795734f1e7bcc936a920d2 104 SMART SM00739 4 31 9.8E-4 T 10-03-2017 IPR005824 KOW RG49_RS07670 40408a53c61a4484600a77de84b19574 254 Pfam PF12697 Alpha/beta hydrolase family 19 246 4.4E-19 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS07670 40408a53c61a4484600a77de84b19574 254 Gene3D G3DSA:3.40.50.1820 4 253 1.3E-48 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS07670 40408a53c61a4484600a77de84b19574 254 SUPERFAMILY SSF53474 12 253 2.53E-51 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS22680 ff6960d0cb988b94c8053c5b568dbb89 487 Pfam PF14559 Tetratricopeptide repeat 354 418 1.4E-10 T 10-03-2017 RG49_RS22680 ff6960d0cb988b94c8053c5b568dbb89 487 Gene3D G3DSA:3.30.2010.10 68 150 1.3E-15 T 10-03-2017 RG49_RS22680 ff6960d0cb988b94c8053c5b568dbb89 487 Gene3D G3DSA:1.25.40.10 310 453 1.3E-14 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22680 ff6960d0cb988b94c8053c5b568dbb89 487 SUPERFAMILY SSF48452 313 428 5.48E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22680 ff6960d0cb988b94c8053c5b568dbb89 487 Pfam PF01435 Peptidase family M48 72 259 3.5E-26 T 10-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 RG49_RS22680 ff6960d0cb988b94c8053c5b568dbb89 487 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 4 484 42.733 T 10-03-2017 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 SMART SM00357 6 70 6.4E-28 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 PIRSF PIRSF002599 1 70 7.8E-24 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 PRINTS PR00050 Cold shock protein signature 28 37 1.4E-16 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 PRINTS PR00050 Cold shock protein signature 7 22 1.4E-16 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 PRINTS PR00050 Cold shock protein signature 43 61 1.4E-16 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 SUPERFAMILY SSF50249 3 69 6.86E-25 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 Gene3D G3DSA:2.40.50.140 5 68 3.3E-31 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 2.9E-31 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02350 b98c3a56239a4d41bb1c4e941f252f75 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS19270 cf2867127a5202a0d2d1b7f3fda6ae3a 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 124 3.1E-27 T 10-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 RG49_RS19270 cf2867127a5202a0d2d1b7f3fda6ae3a 334 Gene3D G3DSA:3.40.50.720 7 148 2.6E-41 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS19270 cf2867127a5202a0d2d1b7f3fda6ae3a 334 SUPERFAMILY SSF51735 7 158 4.2E-42 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS19270 cf2867127a5202a0d2d1b7f3fda6ae3a 334 SUPERFAMILY SSF55347 132 296 4.25E-23 T 10-03-2017 RG49_RS19270 cf2867127a5202a0d2d1b7f3fda6ae3a 334 Gene3D G3DSA:3.30.360.10 149 331 1.6E-66 T 10-03-2017 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 187 4.0E-34 T 10-03-2017 IPR023214 HAD-like domain RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 88 187 3.2E-14 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 SUPERFAMILY SSF56784 3 213 5.56E-49 T 10-03-2017 IPR023214 HAD-like domain RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 Gene3D G3DSA:3.40.50.1000 91 211 3.0E-41 T 10-03-2017 IPR023214 HAD-like domain RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 Gene3D G3DSA:3.40.50.1000 3 17 3.0E-41 T 10-03-2017 IPR023214 HAD-like domain RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 181 2.5E-6 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 Gene3D G3DSA:1.10.150.240 18 86 5.7E-13 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 1.8E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 1.8E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 100 113 1.8E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 1.8E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS24745 b155c13b8d9cae0d25a9e0cd7030e6cf 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 176 189 1.8E-10 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS18465 33e7dc7d11d7b539319895ea6c933e23 142 PIRSF PIRSF002181 1 142 5.9E-51 T 10-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 RG49_RS18465 33e7dc7d11d7b539319895ea6c933e23 142 Gene3D G3DSA:3.90.1180.10 3 141 3.4E-65 T 10-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 RG49_RS18465 33e7dc7d11d7b539319895ea6c933e23 142 SUPERFAMILY SSF52161 1 140 1.83E-60 T 10-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 RG49_RS18465 33e7dc7d11d7b539319895ea6c933e23 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 10-03-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 RG49_RS18465 33e7dc7d11d7b539319895ea6c933e23 142 Pfam PF00572 Ribosomal protein L13 15 138 6.2E-57 T 10-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 RG49_RS18465 33e7dc7d11d7b539319895ea6c933e23 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 5.6E-68 T 10-03-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18465 33e7dc7d11d7b539319895ea6c933e23 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.455 T 10-03-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 RG49_RS10915 46caa69780821a1c8b8b3d0bd5790569 151 Pfam PF07977 FabA-like domain 17 141 1.9E-40 T 10-03-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS10915 46caa69780821a1c8b8b3d0bd5790569 151 SUPERFAMILY SSF54637 10 149 1.13E-50 T 10-03-2017 IPR029069 HotDog domain RG49_RS10915 46caa69780821a1c8b8b3d0bd5790569 151 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 8 146 2.4E-60 T 10-03-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS10915 46caa69780821a1c8b8b3d0bd5790569 151 Gene3D G3DSA:3.10.129.10 4 147 5.6E-59 T 10-03-2017 IPR029069 HotDog domain RG49_RS10915 46caa69780821a1c8b8b3d0bd5790569 151 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 8 149 37.519 T 10-03-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS07450 2d7357f35ef951f8f9744f25d5213bb8 134 PIRSF PIRSF000178 1 134 2.4E-33 T 10-03-2017 RG49_RS07450 2d7357f35ef951f8f9744f25d5213bb8 134 SUPERFAMILY SSF81343 7 134 4.8E-37 T 10-03-2017 RG49_RS07450 2d7357f35ef951f8f9744f25d5213bb8 134 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 12 131 4.1E-40 T 10-03-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07450 2d7357f35ef951f8f9744f25d5213bb8 134 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 128 4.5E-31 T 10-03-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07450 2d7357f35ef951f8f9744f25d5213bb8 134 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 14 38 - T 10-03-2017 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07450 2d7357f35ef951f8f9744f25d5213bb8 134 Gene3D G3DSA:1.20.1300.10 8 134 9.1E-44 T 10-03-2017 RG49_RS07450 2d7357f35ef951f8f9744f25d5213bb8 134 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 89 102 - T 10-03-2017 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS10835 7362a2591a895bf47e3333890b401d15 235 ProSitePatterns PS01318 TsaA-like domain signature. 87 98 - T 10-03-2017 IPR023368 Uncharacterised protein family UPF0066, conserved site RG49_RS10835 7362a2591a895bf47e3333890b401d15 235 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 149 3.4E-62 T 10-03-2017 IPR023370 TsaA-like domain RG49_RS10835 7362a2591a895bf47e3333890b401d15 235 Gene3D G3DSA:2.40.30.70 4 157 1.1E-52 T 10-03-2017 IPR023370 TsaA-like domain RG49_RS10835 7362a2591a895bf47e3333890b401d15 235 Pfam PF01980 Uncharacterised protein family UPF0066 21 142 1.2E-41 T 10-03-2017 IPR023370 TsaA-like domain RG49_RS10835 7362a2591a895bf47e3333890b401d15 235 SUPERFAMILY SSF118196 1 229 6.8E-85 T 10-03-2017 IPR023370 TsaA-like domain RG49_RS10945 6dc7d1e6e71851bc200d82e5e465a683 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 244 40.266 T 10-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 RG49_RS10945 6dc7d1e6e71851bc200d82e5e465a683 252 SUPERFAMILY SSF64005 18 239 3.27E-88 T 10-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 RG49_RS10945 6dc7d1e6e71851bc200d82e5e465a683 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 18 243 6.5E-108 T 10-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 RG49_RS10945 6dc7d1e6e71851bc200d82e5e465a683 252 Gene3D G3DSA:3.40.1180.10 18 246 6.1E-99 T 10-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 RG49_RS10945 6dc7d1e6e71851bc200d82e5e465a683 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 189 206 - T 10-03-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 RG49_RS10945 6dc7d1e6e71851bc200d82e5e465a683 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 243 6.7E-82 T 10-03-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 RG49_RS09305 481ece16c82b6c1a74c500446977b0c9 320 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 25 320 7.9E-160 T 10-03-2017 IPR010068 Periplasmic binding protein TauA GO:0015734|GO:0042597 RG49_RS09305 481ece16c82b6c1a74c500446977b0c9 320 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 24 239 1.8E-24 T 10-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 RG49_RS09305 481ece16c82b6c1a74c500446977b0c9 320 SUPERFAMILY SSF53850 34 307 2.38E-45 T 10-03-2017 RG49_RS09305 481ece16c82b6c1a74c500446977b0c9 320 Gene3D G3DSA:3.40.190.10 106 214 2.1E-21 T 10-03-2017 RG49_RS09305 481ece16c82b6c1a74c500446977b0c9 320 SMART SM00062 24 239 1.9E-29 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS09305 481ece16c82b6c1a74c500446977b0c9 320 Gene3D G3DSA:3.40.190.10 66 101 4.6E-4 T 10-03-2017 RG49_RS09305 481ece16c82b6c1a74c500446977b0c9 320 Gene3D G3DSA:3.40.190.10 215 246 4.6E-4 T 10-03-2017 RG49_RS08300 f26d2821d008f1aeab38380a4876cf5f 407 Pfam PF00529 HlyD membrane-fusion protein of T1SS 94 378 5.3E-11 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS08300 f26d2821d008f1aeab38380a4876cf5f 407 Gene3D G3DSA:2.40.50.100 124 155 9.5E-8 T 10-03-2017 RG49_RS08300 f26d2821d008f1aeab38380a4876cf5f 407 Gene3D G3DSA:2.40.50.100 207 238 9.5E-8 T 10-03-2017 RG49_RS08300 f26d2821d008f1aeab38380a4876cf5f 407 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 203 391 1.3E-29 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS08300 f26d2821d008f1aeab38380a4876cf5f 407 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 109 313 1.8E-58 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS08300 f26d2821d008f1aeab38380a4876cf5f 407 SUPERFAMILY SSF111369 118 318 8.76E-11 T 10-03-2017 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 10-03-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 28.976 T 10-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 Gene3D G3DSA:3.30.470.20 94 219 2.4E-50 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 235 7.4E-86 T 10-03-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 Pfam PF01259 SAICAR synthetase 6 230 1.5E-57 T 10-03-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 10-03-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 SUPERFAMILY SSF56104 3 232 9.81E-76 T 10-03-2017 RG49_RS22780 b3550340b861a18dbbd2e853824eb6ea 237 Gene3D G3DSA:3.30.200.20 7 93 3.4E-32 T 10-03-2017 RG49_RS12050 59bd70e631fe0e3e5f6ba0e4fbdaef5d 201 Pfam PF04972 BON domain 55 122 3.7E-20 T 10-03-2017 IPR007055 BON domain RG49_RS12050 59bd70e631fe0e3e5f6ba0e4fbdaef5d 201 Pfam PF04972 BON domain 135 199 8.9E-20 T 10-03-2017 IPR007055 BON domain RG49_RS12050 59bd70e631fe0e3e5f6ba0e4fbdaef5d 201 SMART SM00749 60 123 2.9E-13 T 10-03-2017 IPR014004 Transport-associated and nodulation domain, bacteria RG49_RS12050 59bd70e631fe0e3e5f6ba0e4fbdaef5d 201 SMART SM00749 139 201 1.0E-10 T 10-03-2017 IPR014004 Transport-associated and nodulation domain, bacteria RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 406 1.1E-45 T 10-03-2017 IPR000160 GGDEF domain RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 SUPERFAMILY SSF55785 148 250 5.76E-15 T 10-03-2017 IPR000014 PAS domain RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 SMART SM00267 242 410 1.1E-66 T 10-03-2017 IPR000160 GGDEF domain RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 SMART SM00091 129 198 0.0039 T 10-03-2017 IPR000014 PAS domain RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 SMART SM00091 3 70 4.1 T 10-03-2017 IPR000014 PAS domain RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 Gene3D G3DSA:3.30.70.270 254 408 1.1E-46 T 10-03-2017 RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 Pfam PF08448 PAS fold 142 244 3.4E-8 T 10-03-2017 IPR013656 PAS fold-4 RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 SUPERFAMILY SSF55073 258 408 3.3E-43 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 130 249 1.6E-12 T 10-03-2017 IPR000014 PAS domain RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 Gene3D G3DSA:3.30.450.20 126 240 3.0E-11 T 10-03-2017 RG49_RS03820 4039408fba9d8e89f5375efc1ee5c25d 410 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 249 408 4.3E-44 T 10-03-2017 IPR000160 GGDEF domain RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 6.8E-40 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 6.8E-40 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 6.8E-40 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 6.8E-40 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 6.8E-40 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 6.8E-40 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 SUPERFAMILY SSF48168 10 221 4.71E-74 T 10-03-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 SUPERFAMILY SSF51998 222 740 8.55E-171 T 10-03-2017 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 Gene3D G3DSA:3.20.70.20 398 559 2.6E-44 T 10-03-2017 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 Gene3D G3DSA:3.20.70.20 129 344 2.6E-44 T 10-03-2017 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 Gene3D G3DSA:3.20.70.20 610 700 2.6E-44 T 10-03-2017 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 142 219 2.9E-12 T 10-03-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 731 7.4E-120 T 10-03-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 3.6E-181 T 10-03-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS23940 f9d2eccb4ff08f489d1e0eba3537db2b 761 Pfam PF03477 ATP cone domain 6 92 2.8E-15 T 10-03-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 RG49_RS14475 11479371a3ebfb9010278baf71307750 308 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 17 300 9.7E-154 T 10-03-2017 RG49_RS14475 11479371a3ebfb9010278baf71307750 308 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 8 301 21.111 T 10-03-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 RG49_RS14475 11479371a3ebfb9010278baf71307750 308 PIRSF PIRSF005355 1 306 1.7E-100 T 10-03-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 RG49_RS14475 11479371a3ebfb9010278baf71307750 308 Pfam PF01040 UbiA prenyltransferase family 26 273 5.1E-38 T 10-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 SUPERFAMILY SSF54211 79 159 3.54E-27 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.7E-30 T 10-03-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 34.99 T 10-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 1.5E-29 T 10-03-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 10-03-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 163 1.4E-71 T 10-03-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 Gene3D G3DSA:3.30.160.20 10 72 7.0E-31 T 10-03-2017 IPR014720 Double-stranded RNA-binding domain RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 SUPERFAMILY SSF54768 9 75 5.13E-24 T 10-03-2017 RG49_RS18085 5e26b9261841fedfc3f886e196ad600b 167 Gene3D G3DSA:3.30.230.10 76 159 1.1E-33 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Hamap MF_01961 Catalase-peroxidase [katG]. 11 726 39.608 T 10-03-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 ProSitePatterns PS00436 Peroxidases active site signature. 97 108 - T 10-03-2017 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Pfam PF00141 Peroxidase 77 396 2.9E-48 T 10-03-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Pfam PF00141 Peroxidase 403 700 4.5E-35 T 10-03-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00458 Haem peroxidase superfamily signature 259 274 3.4E-19 T 10-03-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00458 Haem peroxidase superfamily signature 318 333 3.4E-19 T 10-03-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00458 Haem peroxidase superfamily signature 157 174 3.4E-19 T 10-03-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00458 Haem peroxidase superfamily signature 175 187 3.4E-19 T 10-03-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00458 Haem peroxidase superfamily signature 97 111 3.4E-19 T 10-03-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 259 269 - T 10-03-2017 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Gene3D G3DSA:1.10.520.10 54 251 5.6E-69 T 10-03-2017 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Gene3D G3DSA:1.10.520.10 432 578 2.3E-52 T 10-03-2017 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Gene3D G3DSA:1.10.520.10 704 725 2.3E-52 T 10-03-2017 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 SUPERFAMILY SSF48113 29 429 2.06E-141 T 10-03-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 18 726 0.0 T 10-03-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Gene3D G3DSA:1.10.420.10 579 700 9.6E-47 T 10-03-2017 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 74 99 8.4E-53 T 10-03-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 479 505 8.4E-53 T 10-03-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 33 55 8.4E-53 T 10-03-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 267 290 8.4E-53 T 10-03-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 59 72 8.4E-53 T 10-03-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Gene3D G3DSA:1.10.420.10 252 274 5.8E-46 T 10-03-2017 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 Gene3D G3DSA:1.10.420.10 310 407 5.8E-46 T 10-03-2017 RG49_RS14410 ebd5357d3ce128574f709ea93cbd420c 726 SUPERFAMILY SSF48113 435 725 7.51E-106 T 10-03-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 SUPERFAMILY SSF81336 95 265 7.32E-50 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 PRINTS PR00123 ATP synthase A subunit signature 104 120 3.2E-15 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 PRINTS PR00123 ATP synthase A subunit signature 203 225 3.2E-15 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 PRINTS PR00123 ATP synthase A subunit signature 251 266 3.2E-15 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 38 266 4.3E-43 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 Gene3D G3DSA:1.20.120.220 96 271 9.9E-59 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 Pfam PF00119 ATP synthase A chain 46 265 7.1E-56 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 ProSitePatterns PS00449 ATP synthase a subunit signature. 206 215 - T 10-03-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 RG49_RS15520 cffe2ccf494694423271744bb8ba736c 271 Hamap MF_01393 ATP synthase subunit a [atpB]. 12 271 16.155 T 10-03-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 Gene3D G3DSA:3.40.50.300 9 283 1.2E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.6E-11 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 PRINTS PR00315 GTP-binding elongation factor signature 15 28 6.6E-11 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 PRINTS PR00315 GTP-binding elongation factor signature 137 146 6.6E-11 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.6E-11 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 PRINTS PR00315 GTP-binding elongation factor signature 65 73 6.6E-11 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 Pfam PF00009 Elongation factor Tu GTP binding domain 13 277 1.1E-46 T 10-03-2017 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 SUPERFAMILY SSF52540 10 277 8.73E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 Pfam PF16658 Class II release factor RF3, C-terminal domain 387 514 4.6E-47 T 10-03-2017 IPR032090 Peptide chain release factor 3, C-terminal RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 Gene3D G3DSA:3.30.70.870 395 463 6.6E-14 T 10-03-2017 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 156 1.5E-18 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 527 52.615 T 10-03-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 SUPERFAMILY SSF54980 393 468 1.29E-17 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 SUPERFAMILY SSF50447 262 393 2.03E-27 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 Pfam PF03144 Elongation factor Tu domain 2 314 380 3.5E-11 T 10-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 3 529 0.0 T 10-03-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 RG49_RS12055 8c90c0cef6706a2004594723465e19fe 529 Gene3D G3DSA:2.40.30.10 293 394 9.5E-24 T 10-03-2017 RG49_RS19585 829ccc807bb107b78bc485e05956cfac 140 Pfam PF06853 Protein of unknown function (DUF1249) 21 134 8.4E-43 T 10-03-2017 IPR009659 Protein of unknown function DUF1249 RG49_RS04560 79af3dc85eb93a5d9324428101e66400 269 Pfam PF13371 Tetratricopeptide repeat 187 259 5.3E-27 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS04560 79af3dc85eb93a5d9324428101e66400 269 Gene3D G3DSA:1.25.40.10 188 258 6.2E-5 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS04560 79af3dc85eb93a5d9324428101e66400 269 Pfam PF13369 Transglutaminase-like superfamily 33 184 1.1E-39 T 10-03-2017 IPR032698 Protein SirB1, N-terminal RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Gene3D G3DSA:2.40.160.50 708 807 6.9E-20 T 10-03-2017 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Gene3D G3DSA:2.40.160.50 392 669 6.9E-20 T 10-03-2017 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Pfam PF01103 Surface antigen 448 810 8.6E-106 T 10-03-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Pfam PF07244 Surface antigen variable number repeat 348 421 4.1E-13 T 10-03-2017 IPR010827 Surface antigen variable number GO:0019867 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Pfam PF07244 Surface antigen variable number repeat 92 172 1.1E-10 T 10-03-2017 IPR010827 Surface antigen variable number GO:0019867 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Pfam PF07244 Surface antigen variable number repeat 266 344 3.6E-11 T 10-03-2017 IPR010827 Surface antigen variable number GO:0019867 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Pfam PF07244 Surface antigen variable number repeat 176 263 5.9E-16 T 10-03-2017 IPR010827 Surface antigen variable number GO:0019867 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 2 810 26.299 T 10-03-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 24 810 1.6E-286 T 10-03-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 RG49_RS10930 a903fc4fe493421cba7148152cf5d580 810 PIRSF PIRSF006076 1 810 1.1E-259 T 10-03-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 SUPERFAMILY SSF53822 61 331 5.44E-78 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 SUPERFAMILY SSF47413 1 59 4.74E-19 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 Gene3D G3DSA:1.10.260.40 2 57 1.6E-26 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 SMART SM00354 1 71 5.4E-36 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.0E-21 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.5E-7 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.5E-7 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 Gene3D G3DSA:3.40.50.2300 167 330 2.0E-48 T 10-03-2017 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 10-03-2017 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 Pfam PF13377 Periplasmic binding protein-like domain 169 329 5.1E-33 T 10-03-2017 RG49_RS24415 4042f243e2a7c9208bd3e6cfe340be7b 346 Gene3D G3DSA:3.40.50.2300 58 166 2.8E-48 T 10-03-2017 RG49_RS05475 43f80aa9c42c08085b9e300c22e49970 277 Pfam PF03783 Curli production assembly/transport component CsgG 41 255 1.3E-80 T 10-03-2017 IPR005534 Curli production assembly/transport component CsgG GO:0030288 RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 SUPERFAMILY SSF69255 361 448 1.41E-32 T 10-03-2017 RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 SUPERFAMILY SSF69349 439 673 3.84E-43 T 10-03-2017 RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 Pfam PF05954 Phage late control gene D protein (GPD) 28 328 5.8E-73 T 10-03-2017 RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 Gene3D G3DSA:3.55.50.10 97 191 6.3E-32 T 10-03-2017 RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 7 517 1.5E-189 T 10-03-2017 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 20 500 3.7E-134 T 10-03-2017 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 SUPERFAMILY SSF69279 7 185 6.8E-49 T 10-03-2017 RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 Gene3D G3DSA:2.40.50.230 367 448 3.3E-40 T 10-03-2017 IPR006531 Gp5 N-terminal RG49_RS10605 9fc30c369b433d87aa9cff8c8bbc9972 713 SUPERFAMILY SSF69279 188 362 3.23E-44 T 10-03-2017 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 Gene3D G3DSA:3.40.50.720 8 120 2.5E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 326 1.1E-38 T 10-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 SUPERFAMILY SSF51735 108 295 6.77E-58 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 Pfam PF01842 ACT domain 345 401 5.2E-7 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 Gene3D G3DSA:3.40.50.720 121 297 3.0E-61 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 Gene3D G3DSA:3.30.70.260 324 409 1.1E-28 T 10-03-2017 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 3.1E-50 T 10-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 10-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 SUPERFAMILY SSF55021 328 409 1.15E-20 T 10-03-2017 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 SUPERFAMILY SSF52283 7 138 1.79E-50 T 10-03-2017 RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 229 245 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS20330 3717bd7ab503d25bbe3ebf6dbc73ec6e 410 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 156 177 - T 10-03-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 Pfam PF08029 HisG, C-terminal domain 223 296 1.4E-24 T 10-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 SUPERFAMILY SSF53850 6 224 2.17E-69 T 10-03-2017 RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 Pfam PF01634 ATP phosphoribosyltransferase 54 219 8.7E-48 T 10-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 SUPERFAMILY SSF54913 226 298 7.11E-22 T 10-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 Gene3D G3DSA:3.40.190.10 2 139 2.0E-54 T 10-03-2017 RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 Gene3D G3DSA:3.30.70.120 226 299 1.7E-31 T 10-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 7 197 3.9E-57 T 10-03-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 200 298 1.1E-33 T 10-03-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 RG49_RS25105 295410b258dce5ae3c18fa232e23ed35 299 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 6 299 35.866 T 10-03-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 Gene3D G3DSA:3.40.50.970 2 182 6.1E-62 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 553 7.3E-34 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 SUPERFAMILY SSF52518 3 186 1.73E-49 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 Gene3D G3DSA:3.40.50.1220 190 357 4.1E-52 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 329 1.0E-36 T 10-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 SUPERFAMILY SSF52518 369 567 7.68E-50 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 590 0.0 T 10-03-2017 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 SUPERFAMILY SSF52467 161 349 2.7E-47 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 4.0E-52 T 10-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 RG49_RS08535 d508375312423fa853fa4a5734c5390d 593 Gene3D G3DSA:3.40.50.970 362 584 6.6E-60 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 316 332 - T 10-03-2017 IPR013793 Porin, Gram-negative type, conserved site RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 232 244 4.0E-17 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 316 333 4.0E-17 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 102 112 4.0E-17 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 158 169 4.0E-17 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 57 68 4.0E-17 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 Gene3D G3DSA:2.40.160.10 22 361 3.4E-106 T 10-03-2017 IPR023614 Porin domain RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00183 E.coli/Salmonella-type porin signature 238 255 2.0E-67 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00183 E.coli/Salmonella-type porin signature 56 74 2.0E-67 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00183 E.coli/Salmonella-type porin signature 102 124 2.0E-67 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 2.0E-67 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00183 E.coli/Salmonella-type porin signature 156 178 2.0E-67 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 PRINTS PR00183 E.coli/Salmonella-type porin signature 272 291 2.0E-67 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 SUPERFAMILY SSF56935 22 361 3.66E-81 T 10-03-2017 RG49_RS06080 73e7c314ff15df843a8cb5dcbc5fe116 361 Pfam PF00267 Gram-negative porin 27 361 4.1E-139 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 Gene3D G3DSA:1.25.40.10 593 702 6.1E-16 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 Pfam PF13429 Tetratricopeptide repeat 561 703 1.1E-6 T 10-03-2017 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 SUPERFAMILY SSF48452 196 226 6.78E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 SUPERFAMILY SSF48452 53 112 6.78E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 SUPERFAMILY SSF48452 504 546 6.78E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 Pfam PF13283 Bacteriophage N adsorption protein A C-term 809 977 8.6E-52 T 10-03-2017 IPR025137 Bacteriophage N4 adsorption protein A, C-terminal RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 SUPERFAMILY SSF48452 592 698 1.68E-16 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 SMART SM00028 612 645 6.8E-4 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 SMART SM00028 646 679 150.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS08380 fcb1d80544dac9b7e076e58da4b195ff 990 SMART SM00028 510 545 400.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 2.4E-37 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 314 323 2.4E-37 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 490 504 2.4E-37 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 390 406 2.4E-37 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 2.4E-37 T 10-03-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:3.30.65.10 745 806 1.5E-26 T 10-03-2017 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:3.30.65.10 588 629 5.1E-11 T 10-03-2017 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:3.30.65.10 708 743 1.7E-11 T 10-03-2017 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 635 1.5E-269 T 10-03-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 SMART SM00437 272 527 6.2E-129 T 10-03-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:2.20.25.10 808 865 4.0E-33 T 10-03-2017 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 SUPERFAMILY SSF57783 704 743 6.12E-7 T 10-03-2017 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 SUPERFAMILY SSF56712 3 609 3.27E-208 T 10-03-2017 IPR023405 DNA topoisomerase, type IA, core domain RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 SUPERFAMILY SSF57783 809 864 1.7E-23 T 10-03-2017 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:2.70.20.10 213 333 1.6E-31 T 10-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:2.70.20.10 338 473 2.8E-37 T 10-03-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 SMART SM00436 133 221 1.2E-48 T 10-03-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 709 745 6.1E-12 T 10-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 597 622 7.2E-6 T 10-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 SUPERFAMILY SSF57783 744 807 1.87E-19 T 10-03-2017 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 SMART SM00493 3 132 1.7E-35 T 10-03-2017 IPR006171 Toprim domain RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:1.10.460.10 164 211 5.3E-60 T 10-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:1.10.460.10 660 666 5.3E-60 T 10-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:1.10.460.10 474 578 5.3E-60 T 10-03-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Pfam PF01751 Toprim domain 5 142 4.8E-34 T 10-03-2017 IPR006171 Toprim domain RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 723 55.223 T 10-03-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Pfam PF01131 DNA topoisomerase 157 565 5.1E-129 T 10-03-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Gene3D G3DSA:3.40.50.140 1 163 2.5E-59 T 10-03-2017 IPR006171 Toprim domain RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Pfam PF08272 Topoisomerase I zinc-ribbon-like 758 793 3.5E-12 T 10-03-2017 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 Pfam PF08272 Topoisomerase I zinc-ribbon-like 824 862 1.2E-22 T 10-03-2017 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 RG49_RS04210 16725acee627b252ee2a45c4c783d2b6 865 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 309 323 - T 10-03-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 RG49_RS03800 cde4572d819220cd8442d2539fbb767c 311 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 10 271 57.866 T 10-03-2017 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 RG49_RS03800 cde4572d819220cd8442d2539fbb767c 311 PIRSF PIRSF004976 1 273 1.2E-77 T 10-03-2017 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 RG49_RS03800 cde4572d819220cd8442d2539fbb767c 311 SUPERFAMILY SSF52402 17 235 1.05E-53 T 10-03-2017 RG49_RS03800 cde4572d819220cd8442d2539fbb767c 311 Pfam PF01171 PP-loop family 42 204 1.7E-13 T 10-03-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 RG49_RS03800 cde4572d819220cd8442d2539fbb767c 311 Gene3D G3DSA:3.40.50.620 23 206 3.3E-21 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 Gene3D G3DSA:1.10.10.10 5 54 1.3E-9 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 Pfam PF00455 DeoR C terminal sensor domain 76 231 1.7E-50 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.8E-6 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.8E-6 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 2.1E-16 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 SUPERFAMILY SSF100950 76 235 7.85E-28 T 10-03-2017 RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 SUPERFAMILY SSF46785 5 58 5.94E-12 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 Gene3D G3DSA:3.40.50.1360 77 222 9.5E-11 T 10-03-2017 RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 SMART SM01134 73 233 7.9E-67 T 10-03-2017 RG49_RS21395 5ff9e087f96614cbb16f5cee3449afae 255 SMART SM00420 6 58 2.9E-25 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS01190 11d7a21e25855b7ad5c18baa0c464900 90 Pfam PF07383 Protein of unknown function (DUF1496) 34 89 3.0E-24 T 10-03-2017 IPR009971 Protein of unknown function DUF1496 RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 SUPERFAMILY SSF52540 199 271 4.23E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 SUPERFAMILY SSF52540 46 97 4.23E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 SUPERFAMILY SSF52540 451 465 4.23E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 SUPERFAMILY SSF52540 500 670 4.23E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 SMART SM00487 23 303 7.6E-6 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 Pfam PF00270 DEAD/DEAH box helicase 31 95 1.3E-5 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 Gene3D G3DSA:3.40.50.300 26 106 2.7E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 Gene3D G3DSA:3.40.50.300 153 168 2.7E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 Gene3D G3DSA:3.40.50.300 211 265 2.7E-17 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 Pfam PF06733 DEAD_2 201 264 1.6E-7 T 10-03-2017 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 Pfam PF13307 Helicase C-terminal domain 532 688 1.2E-23 T 10-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 SMART SM00488 18 294 0.0062 T 10-03-2017 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 RG49_RS07030 f1961c5a6f2852ef21ce220148bd0252 716 SMART SM00491 544 676 4.0E-39 T 10-03-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 SUPERFAMILY SSF53092 7 127 9.94E-15 T 10-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 5.8E-5 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 PRINTS PR00599 Methionine aminopeptidase-1 signature 310 322 5.8E-5 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 Pfam PF00557 Metallopeptidase family M24 134 342 1.7E-65 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 SUPERFAMILY SSF55920 127 355 1.2E-76 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 Gene3D G3DSA:3.90.230.10 127 355 1.8E-84 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 123 3.2E-15 T 10-03-2017 IPR000587 Creatinase, N-terminal GO:0016787 RG49_RS23215 18ef3d524b4fc0349aa965301c32f1ad 361 Gene3D G3DSA:3.40.350.10 4 123 1.8E-15 T 10-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 SMART SM00382 142 327 4.5E-4 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 SUPERFAMILY SSF47917 345 459 2.07E-55 T 10-03-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 460 57.065 T 10-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 130 342 5.6E-64 T 10-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 SUPERFAMILY SSF52540 77 348 1.44E-90 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 Gene3D G3DSA:2.40.10.170 2 75 2.0E-30 T 10-03-2017 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 333 342 - T 10-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 Gene3D G3DSA:3.40.50.300 77 343 3.7E-109 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 Gene3D G3DSA:1.10.1140.10 345 460 4.1E-58 T 10-03-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 460 2.3E-264 T 10-03-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 SUPERFAMILY SSF50615 3 75 1.99E-24 T 10-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS15550 87a0407f808f3b21b2ac263219666221 460 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 72 1.9E-20 T 10-03-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS13680 188e454442e276b26583c7288c3554ac 549 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 546 9.5E-257 T 10-03-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 RG49_RS13680 188e454442e276b26583c7288c3554ac 549 Pfam PF00999 Sodium/hydrogen exchanger family 7 421 5.4E-78 T 10-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 RG49_RS24535 213aa882ca17cd6082f8eb4c042037fb 308 SUPERFAMILY SSF52540 1 239 1.06E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24535 213aa882ca17cd6082f8eb4c042037fb 308 SUPERFAMILY SSF54631 261 305 9.83E-6 T 10-03-2017 RG49_RS24535 213aa882ca17cd6082f8eb4c042037fb 308 Pfam PF00005 ABC transporter 18 162 7.0E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS24535 213aa882ca17cd6082f8eb4c042037fb 308 Gene3D G3DSA:3.40.50.300 1 235 3.7E-75 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24535 213aa882ca17cd6082f8eb4c042037fb 308 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24535 213aa882ca17cd6082f8eb4c042037fb 308 SMART SM00382 26 212 2.2E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24535 213aa882ca17cd6082f8eb4c042037fb 308 Gene3D G3DSA:3.10.580.10 261 305 1.6E-4 T 10-03-2017 RG49_RS06450 29a99a73c8fbca0837073871c144f116 238 SUPERFAMILY SSF161098 8 216 2.75E-37 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06450 29a99a73c8fbca0837073871c144f116 238 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 6 86 2.8E-12 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS06450 29a99a73c8fbca0837073871c144f116 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 25 230 1.7E-15 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06450 29a99a73c8fbca0837073871c144f116 238 Gene3D G3DSA:1.10.3720.10 6 227 4.6E-41 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS12145 a2561793fdfdbd5109672e68505b3712 763 Hamap MF_01070 Phosphoglycerol transferase I [mdoB]. 6 738 54.237 T 10-03-2017 IPR020881 Phosphoglycerol transferase I GO:0005886|GO:0008960|GO:0009250 KEGG: 00561+2.7.8.20 RG49_RS12145 a2561793fdfdbd5109672e68505b3712 763 SUPERFAMILY SSF53649 161 469 4.14E-31 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS12145 a2561793fdfdbd5109672e68505b3712 763 Gene3D G3DSA:3.40.720.10 163 465 4.8E-24 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS12145 a2561793fdfdbd5109672e68505b3712 763 Pfam PF00884 Sulfatase 163 446 3.6E-22 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS17800 f618944b011581cf4ffe2862f30e5ae5 696 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 12 675 2.3E-279 T 10-03-2017 IPR010020 Integral membrane protein, YccS/YhfK RG49_RS17800 f618944b011581cf4ffe2862f30e5ae5 696 Pfam PF12805 FUSC-like inner membrane protein yccS 63 330 5.7E-75 T 10-03-2017 IPR032692 Integral membrane protein YccS, N-terminal RG49_RS17800 f618944b011581cf4ffe2862f30e5ae5 696 Pfam PF13515 Fusaric acid resistance protein-like 377 498 3.8E-19 T 10-03-2017 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 Gene3D G3DSA:2.30.330.10 242 323 4.7E-6 T 10-03-2017 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 PIRSF PIRSF002888 2 331 9.0E-101 T 10-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 321 2.7E-120 T 10-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 SUPERFAMILY SSF101801 249 323 1.57E-12 T 10-03-2017 IPR001543 Surface presentation of antigen (SpoA) RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 Pfam PF02154 Flagellar motor switch protein FliM 38 231 2.6E-80 T 10-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 SUPERFAMILY SSF103039 49 231 3.66E-18 T 10-03-2017 IPR028976 CheC-like domain RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 89 105 2.9E-32 T 10-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 114 133 2.9E-32 T 10-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 2.9E-32 T 10-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 2.9E-32 T 10-03-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 RG49_RS00185 0b2aceb704c9cf7816726884a0248460 334 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 321 1.8E-16 T 10-03-2017 IPR001543 Surface presentation of antigen (SpoA) RG49_RS07130 1ecffde042eb451537578d672b06669e 302 SUPERFAMILY SSF142338 11 295 3.01E-87 T 10-03-2017 RG49_RS07130 1ecffde042eb451537578d672b06669e 302 Pfam PF01933 Uncharacterised protein family UPF0052 12 289 2.8E-79 T 10-03-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 RG49_RS07130 1ecffde042eb451537578d672b06669e 302 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 12 297 1.8E-105 T 10-03-2017 IPR010119 Gluconeogenesis factor RG49_RS07130 1ecffde042eb451537578d672b06669e 302 Hamap MF_00973 Gluconeogenesis factor. 8 300 32.577 T 10-03-2017 IPR010119 Gluconeogenesis factor RG49_RS07130 1ecffde042eb451537578d672b06669e 302 Gene3D G3DSA:3.40.50.10680 82 299 1.2E-54 T 10-03-2017 RG49_RS14890 0e17fa8cdaa99394828d32a82f2ca9b9 208 ProSitePatterns PS00194 Thioredoxin family active site. 41 59 - T 10-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 RG49_RS14890 0e17fa8cdaa99394828d32a82f2ca9b9 208 PIRSF PIRSF001488 1 208 2.2E-92 T 10-03-2017 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL RG49_RS14890 0e17fa8cdaa99394828d32a82f2ca9b9 208 Pfam PF01323 DSBA-like thioredoxin domain 40 197 9.2E-31 T 10-03-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 RG49_RS14890 0e17fa8cdaa99394828d32a82f2ca9b9 208 SUPERFAMILY SSF52833 21 206 1.19E-46 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS14890 0e17fa8cdaa99394828d32a82f2ca9b9 208 Gene3D G3DSA:3.40.30.10 121 203 1.3E-23 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS14890 0e17fa8cdaa99394828d32a82f2ca9b9 208 Gene3D G3DSA:3.40.30.10 1 119 9.9E-45 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS04145 56f79aae5057c73d4c2beb937bad2deb 72 Pfam PF05433 Glycine zipper 2TM domain 34 71 7.6E-8 T 10-03-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 RG49_RS04145 56f79aae5057c73d4c2beb937bad2deb 72 ProDom PD052686 LIPOPROTEIN INDUCIBLE OSMOTICALLY B PRECURSOR SIGNAL MEMBRANE PALMITATE TRANSMEMBRANE SURFACE 12 34 2.0E-6 T 10-03-2017 RG49_RS13060 8e358f58a28e9ec776e56694d4714216 316 Pfam PF01715 IPP transferase 46 290 5.7E-86 T 10-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 RG49_RS13060 8e358f58a28e9ec776e56694d4714216 316 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 12 300 6.5E-126 T 10-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 RG49_RS13060 8e358f58a28e9ec776e56694d4714216 316 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 12 309 29.914 T 10-03-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 RG49_RS13060 8e358f58a28e9ec776e56694d4714216 316 SUPERFAMILY SSF52540 13 157 7.02E-18 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13060 8e358f58a28e9ec776e56694d4714216 316 Gene3D G3DSA:1.10.287.890 207 289 6.8E-35 T 10-03-2017 RG49_RS13060 8e358f58a28e9ec776e56694d4714216 316 Gene3D G3DSA:3.40.50.300 10 178 4.0E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SUPERFAMILY SSF48452 580 737 4.49E-7 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Gene3D G3DSA:1.25.40.10 57 214 5.2E-10 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SMART SM00028 461 494 98.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SMART SM00028 603 636 470.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SMART SM00028 351 384 34.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SMART SM00028 303 336 7.3E-5 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SMART SM00028 385 418 0.33 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SMART SM00028 269 302 500.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Pfam PF05420 Cellulose synthase operon protein C C-terminus (BCSC_C) 802 1136 6.0E-118 T 10-03-2017 IPR008410 Cellulose synthase operon C, C-terminal GO:0019867|GO:0030244 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SUPERFAMILY SSF48452 126 205 3.25E-7 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SUPERFAMILY SSF48452 55 85 3.25E-7 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Gene3D G3DSA:1.25.40.10 596 739 1.2E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Gene3D G3DSA:1.25.40.10 360 553 2.7E-20 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Pfam PF14559 Tetratricopeptide repeat 615 684 1.1E-6 T 10-03-2017 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Pfam PF13432 Tetratricopeptide repeat 274 336 9.1E-7 T 10-03-2017 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Pfam PF13432 Tetratricopeptide repeat 389 442 2.3E-5 T 10-03-2017 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SUPERFAMILY SSF48452 466 545 5.32E-12 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SUPERFAMILY SSF48452 609 660 5.32E-12 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 SUPERFAMILY SSF48452 272 432 1.69E-19 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16865 365fdefb083ff34d6b2105815e91f675 1157 Gene3D G3DSA:1.25.40.10 274 359 2.3E-11 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 Pfam PF00106 short chain dehydrogenase 2 187 1.3E-53 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 Gene3D G3DSA:3.40.50.720 2 232 6.9E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.9E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.9E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.9E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 SUPERFAMILY SSF51735 2 231 1.19E-61 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.1E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.1E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.1E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.1E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02515 01c0a4d391cd4222f59c2cb2c5b1bea8 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.1E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS18275 01051bed14d6f4398c6990af584e887e 385 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 374 3.2E-86 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS18275 01051bed14d6f4398c6990af584e887e 385 Gene3D G3DSA:2.40.50.100 64 97 2.3E-26 T 10-03-2017 RG49_RS18275 01051bed14d6f4398c6990af584e887e 385 Gene3D G3DSA:2.40.50.100 172 207 2.3E-26 T 10-03-2017 RG49_RS18275 01051bed14d6f4398c6990af584e887e 385 Pfam PF00529 HlyD membrane-fusion protein of T1SS 155 359 6.7E-12 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS18275 01051bed14d6f4398c6990af584e887e 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 292 4.9E-15 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS18275 01051bed14d6f4398c6990af584e887e 385 SUPERFAMILY SSF111369 52 299 2.88E-89 T 10-03-2017 RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 Pfam PF00072 Response regulator receiver domain 5 117 4.4E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 SUPERFAMILY SSF52172 3 184 2.57E-43 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 SMART SM00448 3 116 6.2E-46 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 1.3E-28 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 Gene3D G3DSA:3.40.50.2300 3 124 2.8E-41 T 10-03-2017 RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 SMART SM00862 150 225 1.8E-28 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 5.0E-117 T 10-03-2017 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 RG49_RS09135 0e45b31dbd48b4685a1831b0524fc60d 229 Gene3D G3DSA:1.10.10.10 129 226 1.0E-36 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 313 1.1E-30 T 10-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 121 2.0E-49 T 10-03-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 SUPERFAMILY SSF53271 69 306 5.83E-67 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 314 1.7E-127 T 10-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 Gene3D G3DSA:3.40.50.2020 2 159 3.7E-72 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 10-03-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 Gene3D G3DSA:3.40.50.2020 160 285 2.5E-52 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 4 314 49.757 T 10-03-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 RG49_RS04595 55b665c7de7d2354089745562edafe6c 315 SMART SM01400 4 121 5.7E-76 T 10-03-2017 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 7 113 3.6E-34 T 10-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 Gene3D G3DSA:3.50.50.60 335 408 3.3E-12 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 SUPERFAMILY SSF46548 9 135 2.41E-26 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 Gene3D G3DSA:3.50.50.60 266 334 7.2E-12 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 126 394 2.4E-25 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 SUPERFAMILY SSF51971 126 346 4.77E-48 T 10-03-2017 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 Gene3D G3DSA:1.10.1060.10 8 128 1.5E-34 T 10-03-2017 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 Gene3D G3DSA:3.40.50.720 129 265 1.7E-33 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 PRINTS PR00419 Adrenodoxin reductase family signature 290 303 4.1E-17 T 10-03-2017 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 PRINTS PR00419 Adrenodoxin reductase family signature 126 148 4.1E-17 T 10-03-2017 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 PRINTS PR00419 Adrenodoxin reductase family signature 149 162 4.1E-17 T 10-03-2017 RG49_RS24440 78b9d6d68e32d8f0062f745586f1af9b 412 PRINTS PR00419 Adrenodoxin reductase family signature 256 270 4.1E-17 T 10-03-2017 RG49_RS17055 84a56d8720671ad41ff950ee3ffc42e6 280 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 278 6.0E-119 T 10-03-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 RG49_RS17055 84a56d8720671ad41ff950ee3ffc42e6 280 Gene3D G3DSA:3.40.50.150 1 280 2.2E-119 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17055 84a56d8720671ad41ff950ee3ffc42e6 280 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 241 247 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS17055 84a56d8720671ad41ff950ee3ffc42e6 280 SUPERFAMILY SSF53335 9 279 1.36E-99 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17055 84a56d8720671ad41ff950ee3ffc42e6 280 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 161 167 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS17055 84a56d8720671ad41ff950ee3ffc42e6 280 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 266 41.877 T 10-03-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 RG49_RS12255 0392960961edf9131540256e16d1f60f 550 Pfam PF03235 Protein of unknown function DUF262 9 219 5.3E-39 T 10-03-2017 IPR004919 Domain of unknown function DUF262 RG49_RS12255 0392960961edf9131540256e16d1f60f 550 Pfam PF07510 Protein of unknown function (DUF1524) 407 540 1.6E-24 T 10-03-2017 IPR011089 Domain of unknown function DUF1524 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 PIRSF PIRSF037167 1 307 3.6E-151 T 10-03-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 14 305 1.3E-110 T 10-03-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 6 300 54.833 T 10-03-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 204 210 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 Gene3D G3DSA:1.10.8.10 15 106 1.0E-6 T 10-03-2017 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 Pfam PF05175 Methyltransferase small domain 132 215 3.1E-16 T 10-03-2017 IPR007848 Methyltransferase small domain GO:0008168 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 SUPERFAMILY SSF53335 15 293 1.69E-54 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS23425 633248133494d914ae19695f4bf2686e 310 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 13 295 2.4E-139 T 10-03-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 RG49_RS23425 633248133494d914ae19695f4bf2686e 310 Gene3D G3DSA:3.40.50.150 108 289 1.8E-53 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS04175 b7d9b3a05260c79240e03e6dc0fb6f8c 196 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 1 196 48.928 T 10-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 RG49_RS04175 b7d9b3a05260c79240e03e6dc0fb6f8c 196 SUPERFAMILY SSF142695 3 173 1.44E-67 T 10-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 RG49_RS04175 b7d9b3a05260c79240e03e6dc0fb6f8c 196 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 5 194 4.5E-96 T 10-03-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 RG49_RS04175 b7d9b3a05260c79240e03e6dc0fb6f8c 196 Pfam PF00925 GTP cyclohydrolase II 4 170 2.3E-69 T 10-03-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 Gene3D G3DSA:1.10.10.160 86 183 4.7E-33 T 10-03-2017 IPR013986 DExx box DNA helicase domain RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 SUPERFAMILY SSF52540 1 347 1.59E-129 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1087 0.0 T 10-03-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 SUPERFAMILY SSF52980 820 1120 4.72E-100 T 10-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 SUPERFAMILY SSF52540 359 813 3.51E-109 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1122 21.257 T 10-03-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 PIRSF PIRSF000980 1 1122 0.0 T 10-03-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 Gene3D G3DSA:3.40.50.300 342 455 6.7E-8 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 Gene3D G3DSA:3.40.50.300 657 752 6.7E-8 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20930 ebd54a341452c559eeb434dc78c4dc05 1122 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 806 0.0 T 10-03-2017 RG49_RS24345 805640c60a9d0766f8ecef4e3cfdb729 313 SUPERFAMILY SSF53590 3 307 1.18E-101 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS24345 805640c60a9d0766f8ecef4e3cfdb729 313 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 299 3.8E-72 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS24345 805640c60a9d0766f8ecef4e3cfdb729 313 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 9 19 - T 10-03-2017 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 RG49_RS24345 805640c60a9d0766f8ecef4e3cfdb729 313 Gene3D G3DSA:3.90.245.10 1 307 1.7E-106 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS24345 805640c60a9d0766f8ecef4e3cfdb729 313 Hamap MF_01433 Pyrimidine-specific ribonucleoside hydrolase RihB [rihB]. 1 313 86.095 T 10-03-2017 IPR022977 Pyrimidine-specific ribonucleoside hydrolase RihB GO:0046133|GO:0050263 KEGG: 00230+3.2.2.8|KEGG: 00240+3.2.2.8 RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 Pfam PF00270 DEAD/DEAH box helicase 31 195 6.2E-52 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 Gene3D G3DSA:3.40.50.300 6 207 6.7E-82 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 Pfam PF00271 Helicase conserved C-terminal domain 232 340 6.8E-29 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 SMART SM00490 259 340 4.8E-32 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 10-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 SUPERFAMILY SSF52540 75 361 3.81E-73 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 Gene3D G3DSA:3.40.50.300 208 375 1.8E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 Pfam PF12343 Cold shock protein DEAD box A 568 629 1.5E-11 T 10-03-2017 IPR021046 Cold-shock protein, DEAD box A, C-terminal GO:0016817 RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 SMART SM00487 25 223 4.7E-65 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 1 560 47.28 T 10-03-2017 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 RG49_RS18840 63ab99fd94e9336d61e988e8a8953030 629 Pfam PF03880 DbpA RNA binding domain 489 558 2.0E-20 T 10-03-2017 IPR005580 DbpA, RNA-binding domain RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 Pfam PF00889 Elongation factor TS 71 263 1.5E-66 T 10-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 Gene3D G3DSA:3.30.479.20 142 178 1.6E-31 T 10-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 Gene3D G3DSA:3.30.479.20 227 262 1.6E-31 T 10-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 SUPERFAMILY SSF54713 56 139 1.24E-20 T 10-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 10-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 SUPERFAMILY SSF54713 142 281 1.31E-53 T 10-03-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 Hamap MF_00050 Elongation factor Ts [tsf]. 1 280 80.24 T 10-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 Gene3D G3DSA:1.10.8.10 2 55 7.0E-28 T 10-03-2017 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 282 3.1E-123 T 10-03-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 SUPERFAMILY SSF46934 4 54 2.24E-18 T 10-03-2017 IPR009060 UBA-like GO:0005515 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 10-03-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS10965 5c95adf3bad4ca4fb76bb94204974137 283 Gene3D G3DSA:1.10.286.20 183 226 5.7E-20 T 10-03-2017 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 159 234 8.2E-15 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Gene3D G3DSA:3.40.50.510 1 132 2.0E-46 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Gene3D G3DSA:1.10.274.10 270 374 6.4E-31 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 2 127 2.5E-41 T 10-03-2017 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 SUPERFAMILY SSF47831 276 384 3.14E-26 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Pfam PF05524 PEP-utilising enzyme, N-terminal 258 368 2.7E-20 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Pfam PF00381 PTS HPr component phosphorylation site 160 236 3.6E-15 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 SUPERFAMILY SSF52009 355 463 8.89E-20 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Gene3D G3DSA:3.30.1340.10 159 241 1.7E-24 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Pfam PF00391 PEP-utilising enzyme, mobile domain 393 464 1.3E-13 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 PRINTS PR00107 Phosphocarrier protein signature 167 183 9.6E-7 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 PRINTS PR00107 Phosphocarrier protein signature 207 224 9.6E-7 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 PRINTS PR00107 Phosphocarrier protein signature 192 207 9.6E-7 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 SUPERFAMILY SSF53062 1 127 4.71E-29 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Pfam PF03610 PTS system fructose IIA component 4 120 6.8E-28 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 167 174 - T 10-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 SUPERFAMILY SSF55594 158 241 4.32E-19 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS04660 5509eda48bbf12602080c90d3a56a279 472 Gene3D G3DSA:3.50.30.10 375 465 5.5E-18 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 62 312 4.6E-14 T 10-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 Gene3D G3DSA:3.40.50.2300 63 152 6.8E-29 T 10-03-2017 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 Gene3D G3DSA:3.40.50.2300 156 329 1.4E-36 T 10-03-2017 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 TIGRFAM TIGR02417 fruct_sucro_rep: D-fructose-responsive transcription factor 2 328 2.4E-156 T 10-03-2017 IPR012781 D-fructose-responsive transcription factor GO:0003677|GO:0006355|GO:0009750 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 SMART SM00354 1 73 7.4E-32 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 SUPERFAMILY SSF53822 60 314 2.94E-42 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 SUPERFAMILY SSF47413 2 58 9.57E-16 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 50 6.6E-19 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 Gene3D G3DSA:1.10.260.40 1 62 1.1E-24 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS11460 33ee5c7827cf4687d3786823d4b545b0 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 10-03-2017 RG49_RS13965 3b01b7aa56aebbf62a6c2b2f7df35303 543 TIGRFAM TIGR01013 2a58: sodium-dependent inorganic phosphate (Pi) transporter 67 520 2.9E-171 T 10-03-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 RG49_RS13965 3b01b7aa56aebbf62a6c2b2f7df35303 543 Pfam PF02690 Na+/Pi-cotransporter 157 252 3.8E-8 T 10-03-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 RG49_RS13965 3b01b7aa56aebbf62a6c2b2f7df35303 543 Pfam PF02690 Na+/Pi-cotransporter 13 147 1.8E-35 T 10-03-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 RG49_RS13965 3b01b7aa56aebbf62a6c2b2f7df35303 543 SUPERFAMILY SSF109755 321 531 2.93E-23 T 10-03-2017 RG49_RS13965 3b01b7aa56aebbf62a6c2b2f7df35303 543 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 308 5.1E-137 T 10-03-2017 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 RG49_RS01630 bc423eb4945eda55a38aa081b6199bcb 423 SUPERFAMILY SSF101960 11 420 4.18E-114 T 10-03-2017 RG49_RS01630 bc423eb4945eda55a38aa081b6199bcb 423 Pfam PF01458 Uncharacterized protein family (UPF0051) 170 393 3.8E-69 T 10-03-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 RG49_RS01630 bc423eb4945eda55a38aa081b6199bcb 423 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 132 409 3.7E-90 T 10-03-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 16 602 55.571 T 10-03-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 9 602 8.8E-198 T 10-03-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 SMART SM00382 163 320 0.0093 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 Gene3D G3DSA:3.40.50.300 535 583 9.9E-10 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 SUPERFAMILY SSF52540 6 360 7.66E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 Gene3D G3DSA:3.40.50.300 350 382 6.4E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 Gene3D G3DSA:3.40.50.300 112 318 6.4E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 Pfam PF13538 UvrD-like helicase C-terminal domain 534 579 1.0E-14 T 10-03-2017 IPR027785 UvrD-like helicase C-terminal domain RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 SUPERFAMILY SSF52540 281 378 8.63E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 SUPERFAMILY SSF52540 434 602 8.63E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20945 43c5d63879fbf7efa1bb8bd7ee5fb351 608 Pfam PF13604 AAA domain 155 318 1.7E-32 T 10-03-2017 RG49_RS08825 9c09d4f91c9673998805169d3067992e 89 PIRSF PIRSF007028 1 89 4.3E-41 T 10-03-2017 IPR009874 Protein of unknown function DUF1428 RG49_RS08825 9c09d4f91c9673998805169d3067992e 89 Pfam PF07237 Protein of unknown function (DUF1428) 1 75 1.6E-33 T 10-03-2017 IPR009874 Protein of unknown function DUF1428 RG49_RS08825 9c09d4f91c9673998805169d3067992e 89 Gene3D G3DSA:3.30.70.900 1 88 4.2E-43 T 10-03-2017 RG49_RS08825 9c09d4f91c9673998805169d3067992e 89 SUPERFAMILY SSF54909 1 88 3.22E-40 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS15235 7bcb3ae05418b073014427bca8aecada 246 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 60 237 5.2E-82 T 10-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS15235 7bcb3ae05418b073014427bca8aecada 246 Hamap MF_01001 UDP-N-acetyl-D-mannosaminuronic acid transferase [wecG]. 1 246 61.587 T 10-03-2017 IPR023085 UDP-N-acetyl-D-mannosaminuronic acid transferase GO:0009246|GO:0016758 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS15235 7bcb3ae05418b073014427bca8aecada 246 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 66 231 1.4E-52 T 10-03-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 Pfam PF00482 Type II secretion system (T2SS), protein F 72 195 1.0E-31 T 10-03-2017 IPR018076 Type II secretion system F domain RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 Pfam PF00482 Type II secretion system (T2SS), protein F 275 395 1.0E-23 T 10-03-2017 IPR018076 Type II secretion system F domain RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 167 195 1.0E-40 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 370 384 1.0E-40 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 386 405 1.0E-40 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 68 80 1.0E-40 T 10-03-2017 IPR003004 GspF/PilC family RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 405 3.9E-148 T 10-03-2017 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 RG49_RS20000 4de2015ab8cc30186ab0f52669b242df 407 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 167 195 - T 10-03-2017 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 Pfam PF01979 Amidohydrolase family 53 410 2.9E-53 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 Gene3D G3DSA:3.20.20.140 59 370 8.1E-55 T 10-03-2017 RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 TIGRFAM TIGR03314 Se_ssnA: putative selenium metabolism protein SsnA 2 438 6.3E-222 T 10-03-2017 IPR017700 Putative selenium metabolism protein SsnA RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 SUPERFAMILY SSF51338 1 56 7.95E-27 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 SUPERFAMILY SSF51338 361 435 7.95E-27 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 Gene3D G3DSA:2.30.40.10 2 58 3.5E-14 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 Gene3D G3DSA:2.30.40.10 371 413 3.5E-14 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20510 e94761dcff847d1f95213bea957001e5 442 SUPERFAMILY SSF51556 56 353 5.61E-55 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS18675 e49f79e31d9df52e18a789af3b13a1f3 183 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 152 1.0E-55 T 10-03-2017 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 RG49_RS18675 e49f79e31d9df52e18a789af3b13a1f3 183 Pfam PF02470 MlaD protein 39 116 1.3E-21 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 Gene3D G3DSA:3.40.47.10 142 193 2.2E-65 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 Gene3D G3DSA:3.40.47.10 276 391 2.2E-65 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 PIRSF PIRSF000429 1 393 6.3E-130 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 Pfam PF00108 Thiolase, N-terminal domain 4 261 9.1E-103 T 10-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 SUPERFAMILY SSF53901 271 391 4.46E-42 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 10-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 3.3E-141 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 10-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 10-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 Pfam PF02803 Thiolase, C-terminal domain 270 391 9.5E-52 T 10-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 SUPERFAMILY SSF53901 3 269 1.17E-83 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 Gene3D G3DSA:3.40.47.10 3 123 3.6E-73 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS20805 dfd8186b409f025f704cf5b8326bf306 393 Gene3D G3DSA:3.40.47.10 194 275 3.6E-73 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS04325 e95dcf69c366ac7c00165adc12060f86 132 SUPERFAMILY SSF54637 7 130 2.9E-36 T 10-03-2017 IPR029069 HotDog domain RG49_RS04325 e95dcf69c366ac7c00165adc12060f86 132 Gene3D G3DSA:3.10.129.10 5 130 3.3E-41 T 10-03-2017 IPR029069 HotDog domain RG49_RS04325 e95dcf69c366ac7c00165adc12060f86 132 Pfam PF03061 Thioesterase superfamily 26 97 6.9E-18 T 10-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 SUPERFAMILY SSF46894 828 892 6.46E-17 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 ProSitePatterns PS00622 LuxR-type HTH domain signature. 850 877 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 836 850 1.2E-10 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 866 878 1.2E-10 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 850 866 1.2E-10 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 SUPERFAMILY SSF48452 440 803 1.74E-155 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 SUPERFAMILY SSF52540 6 232 9.69E-7 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 Hamap MF_01247 HTH-type transcriptional regulator MalT [malT]. 1 899 41.684 T 10-03-2017 IPR023768 Transcriptional regulator HTH-type, MalT RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 Gene3D G3DSA:3.40.50.300 31 143 7.3E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 Gene3D G3DSA:1.10.10.10 835 893 2.4E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 Pfam PF00196 Bacterial regulatory proteins, luxR family 835 890 1.0E-19 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 SMART SM00421 833 890 5.7E-21 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17475 56b536cd02ed8a727acb9142344361a3 901 Gene3D G3DSA:1.25.40.10 438 808 1.4E-108 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16410 808a1cf12fcd0134360e9c7b817f4368 120 Pfam PF10928 Protein of unknown function (DUF2810) 66 117 3.4E-33 T 10-03-2017 IPR021230 Protein of unknown function DUF2810 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 Gene3D G3DSA:1.10.10.10 126 207 4.4E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 SMART SM00448 4 120 3.8E-15 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 SUPERFAMILY SSF52172 3 135 5.27E-21 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 1.4E-18 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 Hamap MF_00981 Transcriptional regulatory protein RcsB [rcsB]. 1 214 51.521 T 10-03-2017 IPR030864 Transcriptional regulatory protein RcsB GO:0000160|GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 SMART SM00421 148 205 4.2E-16 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 Gene3D G3DSA:3.40.50.2300 1 125 8.3E-21 T 10-03-2017 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.0E-8 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.0E-8 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.0E-8 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 SUPERFAMILY SSF46894 146 207 2.38E-16 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS24030 a4d0d02728a620eaca1f24bb25ab0c46 216 Pfam PF00072 Response regulator receiver domain 6 120 1.2E-24 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS13240 2a0aa537b76cdffcf3f95666d621742b 433 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 365 3.2E-145 T 10-03-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 RG49_RS13240 2a0aa537b76cdffcf3f95666d621742b 433 PIRSF PIRSF004539 1 433 2.0E-181 T 10-03-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 RG49_RS13240 2a0aa537b76cdffcf3f95666d621742b 433 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 433 2.2E-210 T 10-03-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 RG49_RS05825 e2231f6b4a0bfe34b70b06836a27339f 285 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 50 139 2.3E-8 T 10-03-2017 IPR006894 HupH hydrogenase expression protein, C-terminal RG49_RS05825 e2231f6b4a0bfe34b70b06836a27339f 285 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 164 279 3.4E-32 T 10-03-2017 IPR006894 HupH hydrogenase expression protein, C-terminal RG49_RS05825 e2231f6b4a0bfe34b70b06836a27339f 285 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 49 149 1.0E-24 T 10-03-2017 IPR006894 HupH hydrogenase expression protein, C-terminal RG49_RS05825 e2231f6b4a0bfe34b70b06836a27339f 285 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 164 279 7.0E-63 T 10-03-2017 IPR006894 HupH hydrogenase expression protein, C-terminal RG49_RS19385 75f1ddc04ebf9d5bc247ed264936c742 168 Gene3D G3DSA:3.40.470.10 2 163 8.4E-59 T 10-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS19385 75f1ddc04ebf9d5bc247ed264936c742 168 Hamap MF_01956 G/U mismatch-specific DNA glycosylase [mug]. 1 168 51.132 T 10-03-2017 IPR023502 G/U mismatch-specific DNA glycosylase, bacterial GO:0006281|GO:0019104 RG49_RS19385 75f1ddc04ebf9d5bc247ed264936c742 168 SUPERFAMILY SSF52141 2 163 8.5E-48 T 10-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS19385 75f1ddc04ebf9d5bc247ed264936c742 168 Pfam PF03167 Uracil DNA glycosylase superfamily 6 159 1.5E-24 T 10-03-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 RG49_RS03055 f29a216ec3899ba1a9b4ab3e6e62ced1 77 Pfam PF01361 Tautomerase enzyme 2 53 8.1E-15 T 10-03-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 RG49_RS03055 f29a216ec3899ba1a9b4ab3e6e62ced1 77 Hamap MF_00718 Tautomerase PptA [pptA]. 1 75 30.698 T 10-03-2017 IPR017284 Tautomerase PptA GO:0005737|GO:0016862 RG49_RS03055 f29a216ec3899ba1a9b4ab3e6e62ced1 77 PIRSF PIRSF037799 1 77 1.2E-32 T 10-03-2017 IPR017284 Tautomerase PptA GO:0005737|GO:0016862 RG49_RS03055 f29a216ec3899ba1a9b4ab3e6e62ced1 77 SUPERFAMILY SSF55331 2 76 8.74E-18 T 10-03-2017 IPR014347 Tautomerase/MIF superfamily RG49_RS03055 f29a216ec3899ba1a9b4ab3e6e62ced1 77 Gene3D G3DSA:3.30.429.20 1 53 1.2E-10 T 10-03-2017 RG49_RS20910 a4c23d26076794fa60d262ffc28d8875 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 7.2E-6 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20910 a4c23d26076794fa60d262ffc28d8875 156 SUPERFAMILY SSF54523 8 135 4.24E-7 T 10-03-2017 RG49_RS20910 a4c23d26076794fa60d262ffc28d8875 156 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20910 a4c23d26076794fa60d262ffc28d8875 156 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 1 24 2.2E-7 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS25195 aef5b1515c3d5c7495637911ca4f9172 247 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 247 48.798 T 10-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25195 aef5b1515c3d5c7495637911ca4f9172 247 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 1 246 8.2E-92 T 10-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25195 aef5b1515c3d5c7495637911ca4f9172 247 Pfam PF02654 Cobalamin-5-phosphate synthase 9 244 6.1E-54 T 10-03-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 Gene3D G3DSA:3.40.50.1100 40 139 8.3E-40 T 10-03-2017 RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 30 48 - T 10-03-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 SUPERFAMILY SSF53686 4 289 9.3E-93 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 TIGRFAM TIGR01138 cysM: cysteine synthase B 3 292 3.3E-171 T 10-03-2017 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 281 4.8E-69 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 Gene3D G3DSA:3.40.50.1100 2 39 1.8E-80 T 10-03-2017 RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 Gene3D G3DSA:3.40.50.1100 146 297 1.8E-80 T 10-03-2017 RG49_RS23020 1e639ce475e367de4527354bd65361c3 303 TIGRFAM TIGR01136 cysKM: cysteine synthase 5 292 3.0E-127 T 10-03-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 RG49_RS22955 5614f958475d8de6dafbed3580da5892 141 Hamap MF_01127 Acetyltransferase YpeA [ypeA]. 1 141 46.559 T 10-03-2017 IPR023072 Acetyltransferase, YpeA GO:0016747 RG49_RS22955 5614f958475d8de6dafbed3580da5892 141 Gene3D G3DSA:3.40.630.30 1 123 3.0E-34 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS22955 5614f958475d8de6dafbed3580da5892 141 Pfam PF00583 Acetyltransferase (GNAT) family 48 124 1.3E-15 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS22955 5614f958475d8de6dafbed3580da5892 141 SUPERFAMILY SSF55729 1 128 2.13E-29 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS11005 4ddf5054a88b91559aee6478ea4a0b69 128 Hamap MF_01519 UPF0325 protein YaeH [yaeH]. 1 126 32.845 T 10-03-2017 IPR020911 Uncharacterised protein family UPF0325 RG49_RS11005 4ddf5054a88b91559aee6478ea4a0b69 128 Pfam PF11944 Protein of unknown function (DUF3461) 1 125 2.9E-57 T 10-03-2017 IPR020911 Uncharacterised protein family UPF0325 RG49_RS11005 4ddf5054a88b91559aee6478ea4a0b69 128 ProDom PD080106 UPF0325 YAEH STRUCTURAL ECA1027 VV11856 YPTB3007 PBPRA2971 VV2560 VF1965 VC2264 1 125 2.0E-67 T 10-03-2017 IPR020911 Uncharacterised protein family UPF0325 RG49_RS06545 751a52fa3887c8b77054d031eba59fc3 366 SUPERFAMILY SSF69279 15 188 1.5E-28 T 10-03-2017 RG49_RS06545 751a52fa3887c8b77054d031eba59fc3 366 Gene3D G3DSA:3.55.50.10 116 182 8.5E-5 T 10-03-2017 RG49_RS06545 751a52fa3887c8b77054d031eba59fc3 366 Pfam PF05954 Phage late control gene D protein (GPD) 62 345 8.8E-38 T 10-03-2017 RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 PRINTS PR00969 Pili chaperone signature 173 188 2.2E-36 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 PRINTS PR00969 Pili chaperone signature 138 153 2.2E-36 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 PRINTS PR00969 Pili chaperone signature 38 47 2.2E-36 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 PRINTS PR00969 Pili chaperone signature 83 104 2.2E-36 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 PRINTS PR00969 Pili chaperone signature 112 129 2.2E-36 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 Gene3D G3DSA:2.60.40.1070 160 238 1.8E-26 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 Gene3D G3DSA:2.60.40.360 37 157 1.1E-45 T 10-03-2017 IPR008962 PapD-like RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 37 156 3.5E-38 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 SUPERFAMILY SSF49354 37 156 1.75E-40 T 10-03-2017 IPR008962 PapD-like RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 SUPERFAMILY SSF49584 151 236 1.96E-20 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 180 233 7.9E-11 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS12425 46524d73edb61babbeda9f9e6f6734dc 241 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 111 128 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS24090 52f8ff6d7ba88d7ba836b845ad79c30c 162 Gene3D G3DSA:2.60.40.550 23 104 4.7E-41 T 10-03-2017 IPR023189 Proteinase inhibitor I11, ecotin domain RG49_RS24090 52f8ff6d7ba88d7ba836b845ad79c30c 162 Pfam PF03974 Ecotin 30 152 5.2E-53 T 10-03-2017 IPR023189 Proteinase inhibitor I11, ecotin domain RG49_RS24090 52f8ff6d7ba88d7ba836b845ad79c30c 162 PIRSF PIRSF006865 1 162 3.0E-65 T 10-03-2017 IPR005658 Proteinase inhibitor I11, ecotin RG49_RS24090 52f8ff6d7ba88d7ba836b845ad79c30c 162 SUPERFAMILY SSF49772 26 160 6.41E-58 T 10-03-2017 IPR023189 Proteinase inhibitor I11, ecotin domain RG49_RS24090 52f8ff6d7ba88d7ba836b845ad79c30c 162 Gene3D G3DSA:4.10.1230.10 105 161 1.0E-31 T 10-03-2017 IPR027438 Ecotin, C-terminal RG49_RS24090 52f8ff6d7ba88d7ba836b845ad79c30c 162 Hamap MF_00706 Ecotin [eco]. 1 162 42.133 T 10-03-2017 IPR023084 Proteinase inhibitor I11, ecotin, gammaproteobacteria RG49_RS05560 05b021c6d1aa356af80558101e262bbf 807 SUPERFAMILY SSF48452 361 505 1.81E-5 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS05560 05b021c6d1aa356af80558101e262bbf 807 SUPERFAMILY SSF48452 95 164 3.26E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS05560 05b021c6d1aa356af80558101e262bbf 807 TIGRFAM TIGR03939 PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA 17 807 5.1E-295 T 10-03-2017 IPR023870 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA GO:0022891|GO:0042710 RG49_RS05560 05b021c6d1aa356af80558101e262bbf 807 Gene3D G3DSA:1.25.40.10 360 505 1.7E-5 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS05560 05b021c6d1aa356af80558101e262bbf 807 SMART SM00028 98 131 0.0059 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS05560 05b021c6d1aa356af80558101e262bbf 807 Gene3D G3DSA:1.25.40.10 98 170 3.4E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 Gene3D G3DSA:3.50.50.60 6 183 8.4E-47 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 Gene3D G3DSA:3.50.50.60 268 354 8.4E-47 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 Pfam PF01494 FAD binding domain 6 338 8.9E-28 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 390 2.8E-133 T 10-03-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 294 307 - T 10-03-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 6.2E-19 T 10-03-2017 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 6.2E-19 T 10-03-2017 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 6.2E-19 T 10-03-2017 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 6.2E-19 T 10-03-2017 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 SUPERFAMILY SSF51905 6 178 3.74E-61 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS07795 48e6dbcfb9f4e14ada66bf5eba60bce4 391 SUPERFAMILY SSF51905 267 383 3.74E-61 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23575 b559359a9c6050f5effc7e3156227d89 214 SUPERFAMILY SSF47616 90 207 1.16E-8 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS23575 b559359a9c6050f5effc7e3156227d89 214 SUPERFAMILY SSF52833 13 87 4.99E-16 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS23575 b559359a9c6050f5effc7e3156227d89 214 Gene3D G3DSA:3.40.30.10 13 99 1.5E-18 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS23575 b559359a9c6050f5effc7e3156227d89 214 Gene3D G3DSA:1.20.1050.10 100 212 8.0E-46 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS23575 b559359a9c6050f5effc7e3156227d89 214 Pfam PF14834 Glutathione S-transferase, C-terminal domain 95 211 1.6E-71 T 10-03-2017 RG49_RS23575 b559359a9c6050f5effc7e3156227d89 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 15 86 5.1E-12 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS00055 fe1fce8a40d2a45c26d00d09b86f6b2d 283 Gene3D G3DSA:3.40.50.880 2 278 7.2E-85 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS00055 fe1fce8a40d2a45c26d00d09b86f6b2d 283 PIRSF PIRSF037798 1 283 1.9E-148 T 10-03-2017 IPR017283 Protein deglycase HchA KEGG: 00620+4.2.1.130|MetaCyc: PWY-901 RG49_RS00055 fe1fce8a40d2a45c26d00d09b86f6b2d 283 Hamap MF_01046 Protein deglycase HchA [hchA]. 1 283 66.915 T 10-03-2017 IPR017283 Protein deglycase HchA KEGG: 00620+4.2.1.130|MetaCyc: PWY-901 RG49_RS00055 fe1fce8a40d2a45c26d00d09b86f6b2d 283 SUPERFAMILY SSF52317 7 278 6.67E-55 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS16735 2c2f7ff8626da4cb8f627a99be8d0d61 146 Gene3D G3DSA:3.40.630.30 1 142 4.4E-26 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS16735 2c2f7ff8626da4cb8f627a99be8d0d61 146 Pfam PF13673 Acetyltransferase (GNAT) domain 47 124 2.6E-15 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS16735 2c2f7ff8626da4cb8f627a99be8d0d61 146 SUPERFAMILY SSF55729 1 141 9.04E-26 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 Pfam PF01389 OmpA-like transmembrane domain 23 195 1.4E-75 T 10-03-2017 IPR000498 Outer membrane protein OmpA-like, transmembrane domain GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 ProSitePatterns PS01068 OmpA-like domain. 257 301 - T 10-03-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 Pfam PF00691 OmpA family 222 317 1.1E-23 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01021 OMPA domain signature 270 286 3.2E-24 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01021 OMPA domain signature 223 245 3.2E-24 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01021 OMPA domain signature 255 270 3.2E-24 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 Gene3D G3DSA:3.30.1330.60 212 334 2.8E-42 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 SUPERFAMILY SSF56925 22 195 8.89E-47 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01022 Outer membrane protein A signature 279 298 1.5E-73 T 10-03-2017 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01022 Outer membrane protein A signature 313 326 1.5E-73 T 10-03-2017 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01022 Outer membrane protein A signature 107 123 1.5E-73 T 10-03-2017 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01022 Outer membrane protein A signature 165 179 1.5E-73 T 10-03-2017 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01022 Outer membrane protein A signature 179 193 1.5E-73 T 10-03-2017 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01022 Outer membrane protein A signature 240 259 1.5E-73 T 10-03-2017 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 PRINTS PR01022 Outer membrane protein A signature 211 226 1.5E-73 T 10-03-2017 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 Gene3D G3DSA:2.40.160.20 11 211 2.4E-80 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS05935 19ba0f718f9b01d9d0d873666790014f 346 SUPERFAMILY SSF103088 211 334 1.44E-36 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS08990 59473cc5528cc4a5cd579c211a8b4d8e 296 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 57 79 - T 10-03-2017 IPR030470 UbiA prenyltransferase conserved site RG49_RS08990 59473cc5528cc4a5cd579c211a8b4d8e 296 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 2 284 18.105 T 10-03-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 RG49_RS08990 59473cc5528cc4a5cd579c211a8b4d8e 296 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 4 282 1.3E-91 T 10-03-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 RG49_RS08990 59473cc5528cc4a5cd579c211a8b4d8e 296 Pfam PF01040 UbiA prenyltransferase family 19 265 1.3E-59 T 10-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 4.4E-5 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 4.4E-5 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 Gene3D G3DSA:1.10.287.130 234 297 9.8E-7 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 Gene3D G3DSA:3.30.565.10 306 449 2.8E-26 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 SMART SM00387 344 452 2.1E-22 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 3 449 3.6E-95 T 10-03-2017 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 449 3.8E-12 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 299 1.4E-9 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 Pfam PF00672 HAMP domain 162 230 5.7E-10 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 SUPERFAMILY SSF47384 218 302 8.44E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 SUPERFAMILY SSF55874 290 449 8.63E-26 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00050 a4e48bf0c9f3acd184c658e76d1e4ae0 452 SMART SM00388 235 301 2.1E-11 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 Gene3D G3DSA:3.60.10.10 1 267 8.9E-88 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 10-03-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 197 213 - T 10-03-2017 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 SUPERFAMILY SSF56219 1 267 2.22E-87 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 266 3.4E-112 T 10-03-2017 RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 223 234 - T 10-03-2017 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 266 6.7E-95 T 10-03-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 RG49_RS01245 afb5765c5d4f554c52bed11f02153167 268 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 259 4.6E-29 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 Gene3D G3DSA:3.40.50.300 144 331 2.9E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 SMART SM00382 184 323 1.9E-26 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 188 320 5.2E-46 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 Pfam PF01434 Peptidase family M41 382 591 8.2E-83 T 10-03-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 612 37.49 T 10-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 Pfam PF06480 FtsH Extracellular 5 93 1.5E-16 T 10-03-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 Gene3D G3DSA:1.10.8.60 332 406 5.6E-29 T 10-03-2017 RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 SUPERFAMILY SSF52540 141 391 7.38E-73 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 SUPERFAMILY SSF140990 402 602 3.79E-73 T 10-03-2017 RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 ProSitePatterns PS00674 AAA-protein family signature. 291 309 - T 10-03-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 RG49_RS18750 be9a89b705d157b2d7358a7f019fb0f8 644 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 100 593 3.7E-248 T 10-03-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 Pfam PF00271 Helicase conserved C-terminal domain 243 351 3.1E-28 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 SMART SM00490 270 351 8.2E-31 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 Pfam PF00270 DEAD/DEAH box helicase 33 206 2.3E-44 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 Gene3D G3DSA:3.40.50.300 232 386 1.3E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 10-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 SUPERFAMILY SSF52540 84 363 4.68E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 Gene3D G3DSA:3.40.50.300 8 231 3.3E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 50.868 T 10-03-2017 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 RG49_RS15315 9e62102c3fed86ead29103fc484a13af 421 SMART SM00487 28 234 1.4E-52 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 Pfam PF01551 Peptidase family M23 313 407 4.5E-33 T 10-03-2017 IPR016047 Peptidase M23 RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 SUPERFAMILY SSF54106 96 139 9.42E-5 T 10-03-2017 IPR018392 LysM domain RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 Pfam PF01476 LysM domain 98 141 2.3E-7 T 10-03-2017 IPR018392 LysM domain RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 SUPERFAMILY SSF51261 169 408 1.88E-69 T 10-03-2017 IPR011055 Duplicated hybrid motif RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 Gene3D G3DSA:2.70.70.10 266 409 2.6E-50 T 10-03-2017 RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 Gene3D G3DSA:3.10.350.10 97 139 8.5E-7 T 10-03-2017 IPR018392 LysM domain RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 SMART SM00257 97 142 4.4E-6 T 10-03-2017 IPR018392 LysM domain RG49_RS00640 f034c6fa46c408eb985fa737a4492ad8 440 Pfam PF08525 Opacity-associated protein A N-terminal motif 12 39 5.4E-9 T 10-03-2017 IPR013731 Opacity-associated protein A, N-terminal RG49_RS00905 97283d74e5c25dd5df066ee27aaf0cb2 454 Pfam PF03315 Serine dehydratase beta chain 3 155 6.8E-57 T 10-03-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 RG49_RS00905 97283d74e5c25dd5df066ee27aaf0cb2 454 Gene3D G3DSA:3.30.1330.90 10 158 2.2E-55 T 10-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 RG49_RS00905 97283d74e5c25dd5df066ee27aaf0cb2 454 Pfam PF03313 Serine dehydratase alpha chain 186 448 9.5E-96 T 10-03-2017 IPR005130 Serine dehydratase-like, alpha subunit RG49_RS00905 97283d74e5c25dd5df066ee27aaf0cb2 454 SUPERFAMILY SSF143548 16 158 1.02E-46 T 10-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 RG49_RS00905 97283d74e5c25dd5df066ee27aaf0cb2 454 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 1.7E-231 T 10-03-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 RG49_RS20890 453121ae4e1098a84bfe62fd567d28b8 176 SUPERFAMILY SSF55811 5 159 6.77E-33 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS20890 453121ae4e1098a84bfe62fd567d28b8 176 Gene3D G3DSA:3.90.79.10 3 151 7.1E-33 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS20890 453121ae4e1098a84bfe62fd567d28b8 176 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS20890 453121ae4e1098a84bfe62fd567d28b8 176 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.5E-7 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS20890 453121ae4e1098a84bfe62fd567d28b8 176 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.5E-7 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS20890 453121ae4e1098a84bfe62fd567d28b8 176 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.961 T 10-03-2017 IPR022927 RNA pyrophosphohydrolase RppH RG49_RS20890 453121ae4e1098a84bfe62fd567d28b8 176 Pfam PF00293 NUDIX domain 7 146 5.1E-27 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS24630 e3538380cbebdd5fa43f0a268deccb3c 165 SUPERFAMILY SSF49401 14 161 2.58E-11 T 10-03-2017 IPR008966 Adhesion domain RG49_RS24630 e3538380cbebdd5fa43f0a268deccb3c 165 Gene3D G3DSA:2.60.40.1090 13 160 1.4E-10 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS24630 e3538380cbebdd5fa43f0a268deccb3c 165 Pfam PF00419 Fimbrial protein 17 162 7.5E-9 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS09040 21f16f854e3ba61149163dd69681337a 172 SUPERFAMILY SSF101307 15 162 4.71E-48 T 10-03-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 RG49_RS09040 21f16f854e3ba61149163dd69681337a 172 PIRSF PIRSF006162 11 169 8.8E-58 T 10-03-2017 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668 RG49_RS09040 21f16f854e3ba61149163dd69681337a 172 Gene3D G3DSA:1.10.3760.10 77 156 1.7E-4 T 10-03-2017 IPR027416 YutG-like domain RG49_RS09040 21f16f854e3ba61149163dd69681337a 172 Pfam PF04608 Phosphatidylglycerophosphatase A 22 162 6.3E-51 T 10-03-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 RG49_RS15965 a4d4ea3ad968ca25c78b95d2bd8c0bc2 272 Pfam PF03180 NLPA lipoprotein 34 272 4.2E-93 T 10-03-2017 IPR004872 Lipoprotein NlpA family RG49_RS15965 a4d4ea3ad968ca25c78b95d2bd8c0bc2 272 Gene3D G3DSA:3.40.190.10 31 162 2.5E-54 T 10-03-2017 RG49_RS15965 a4d4ea3ad968ca25c78b95d2bd8c0bc2 272 SUPERFAMILY SSF53850 34 272 1.22E-76 T 10-03-2017 RG49_RS15965 a4d4ea3ad968ca25c78b95d2bd8c0bc2 272 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 272 3.4E-150 T 10-03-2017 IPR004872 Lipoprotein NlpA family RG49_RS15965 a4d4ea3ad968ca25c78b95d2bd8c0bc2 272 PIRSF PIRSF002854 1 272 1.4E-95 T 10-03-2017 IPR004872 Lipoprotein NlpA family RG49_RS17980 f289a0b2ac24cb282bea44dc2502894f 271 Gene3D G3DSA:2.30.42.10 205 260 3.8E-6 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS17980 f289a0b2ac24cb282bea44dc2502894f 271 ProSitePatterns PS01141 Bacterial type II secretion system protein C signature. 194 220 - T 10-03-2017 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 RG49_RS17980 f289a0b2ac24cb282bea44dc2502894f 271 Pfam PF11356 Type II secretion system protein C 78 152 7.2E-8 T 10-03-2017 IPR024961 Type II secretion system protein C, N-terminal RG49_RS17980 f289a0b2ac24cb282bea44dc2502894f 271 SUPERFAMILY SSF50156 169 254 1.91E-8 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS17980 f289a0b2ac24cb282bea44dc2502894f 271 TIGRFAM TIGR01713 typeII_sec_gspC: type II secretion system protein C 17 256 3.9E-88 T 10-03-2017 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 SMART SM00883 2 95 4.3E-50 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 10-03-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 SUPERFAMILY SSF50129 1 96 1.29E-31 T 10-03-2017 IPR011032 GroES-like RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 24.098 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 Pfam PF00166 Chaperonin 10 Kd subunit 2 95 3.8E-30 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 PRINTS PR00297 10kDa chaperonin signature 25 46 1.9E-27 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 PRINTS PR00297 10kDa chaperonin signature 3 18 1.9E-27 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 PRINTS PR00297 10kDa chaperonin signature 60 72 1.9E-27 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 PRINTS PR00297 10kDa chaperonin signature 82 95 1.9E-27 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS13215 14aed608b903e87469e861e7f4f44d91 97 Gene3D G3DSA:2.30.33.40 1 96 1.2E-32 T 10-03-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 RG49_RS15040 25e3bcac977806b7bb01a8623219d0e6 289 SUPERFAMILY SSF53474 51 283 3.6E-49 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS15040 25e3bcac977806b7bb01a8623219d0e6 289 Gene3D G3DSA:3.40.50.1820 52 283 1.3E-70 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS15040 25e3bcac977806b7bb01a8623219d0e6 289 Pfam PF01738 Dienelactone hydrolase family 60 283 1.8E-77 T 10-03-2017 IPR002925 Dienelactone hydrolase GO:0016787 RG49_RS07260 db49569d9b4de7fd4167ae8610820ddd 346 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 171 180 - T 10-03-2017 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 RG49_RS07260 db49569d9b4de7fd4167ae8610820ddd 346 PIRSF PIRSF005096 2 346 8.3E-129 T 10-03-2017 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 RG49_RS07260 db49569d9b4de7fd4167ae8610820ddd 346 SUPERFAMILY SSF74650 5 343 1.0E-107 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS07260 db49569d9b4de7fd4167ae8610820ddd 346 Gene3D G3DSA:2.70.98.10 9 343 6.3E-117 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS07260 db49569d9b4de7fd4167ae8610820ddd 346 Pfam PF01263 Aldose 1-epimerase 17 342 1.9E-91 T 10-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 RG49_RS07260 db49569d9b4de7fd4167ae8610820ddd 346 TIGRFAM TIGR02636 galM_Leloir: galactose mutarotase 12 343 4.8E-150 T 10-03-2017 IPR013458 Aldose 1-epimerase, bacterial GO:0004034|GO:0006012 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 SUPERFAMILY SSF63380 94 201 3.66E-32 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 Gene3D G3DSA:2.40.30.20 105 199 1.9E-27 T 10-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 Gene3D G3DSA:2.40.30.20 5 104 2.3E-32 T 10-03-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 PIRSF PIRSF000498 1 212 1.6E-77 T 10-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 202 6.6E-92 T 10-03-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 Pfam PF00677 Lumazine binding domain 100 185 1.0E-19 T 10-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 Pfam PF00677 Lumazine binding domain 3 87 2.7E-21 T 10-03-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS01725 ba36ec06b78cd67ac2924910795c560c 213 SUPERFAMILY SSF63380 1 93 6.04E-28 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 267 1.1E-63 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 221 243 - T 10-03-2017 RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 Gene3D G3DSA:3.40.50.1000 1 73 3.8E-50 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 Gene3D G3DSA:3.40.50.1000 176 271 3.8E-50 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 240 6.6E-21 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 267 5.8E-72 T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 SUPERFAMILY SSF56784 1 271 2.16E-62 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07205 eb2913f1c00188b09a667b8f22b6235e 272 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS12785 1c82e6ec7a4b5dfe9ddcca7d3d440604 212 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 44 199 2.0E-72 T 10-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 RG49_RS12785 1c82e6ec7a4b5dfe9ddcca7d3d440604 212 SUPERFAMILY SSF55068 5 208 2.09E-85 T 10-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 RG49_RS12785 1c82e6ec7a4b5dfe9ddcca7d3d440604 212 Gene3D G3DSA:3.30.1060.10 7 199 3.1E-81 T 10-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 RG49_RS12785 1c82e6ec7a4b5dfe9ddcca7d3d440604 212 Pfam PF01625 Peptide methionine sulfoxide reductase 46 199 7.4E-68 T 10-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 RG49_RS12785 1c82e6ec7a4b5dfe9ddcca7d3d440604 212 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 43 205 38.946 T 10-03-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 456 1.4E-24 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 306 5.3E-13 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 SUPERFAMILY SSF47384 231 307 2.94E-13 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 SMART SM00388 244 310 1.6E-15 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 Gene3D G3DSA:3.30.450.20 74 130 7.8E-5 T 10-03-2017 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 SUPERFAMILY SSF103190 35 152 1.61E-13 T 10-03-2017 IPR029151 Periplasmic sensor domain-like RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 SMART SM00387 352 458 8.6E-37 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 SUPERFAMILY SSF55874 300 456 2.49E-44 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 Gene3D G3DSA:1.10.287.130 238 305 2.6E-13 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 Gene3D G3DSA:3.30.565.10 310 456 3.2E-47 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 1.7E-20 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 1.7E-20 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 1.7E-20 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14065 b617dd78099efe385cdcd9a505a991d3 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 1.7E-20 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS19595 ef0dad65ad91b11ac442e559dda68e16 193 SUPERFAMILY SSF53474 3 188 2.66E-21 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS19595 ef0dad65ad91b11ac442e559dda68e16 193 Gene3D G3DSA:3.40.50.1820 3 185 2.0E-16 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS19595 ef0dad65ad91b11ac442e559dda68e16 193 Pfam PF05728 Uncharacterised protein family (UPF0227) 4 188 1.9E-74 T 10-03-2017 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA RG49_RS17880 832ff651a910cda1590a0fc26ef4aba5 128 Hamap MF_00390 Sulfurtransferase TusD [tusD]. 1 128 41.629 T 10-03-2017 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 RG49_RS17880 832ff651a910cda1590a0fc26ef4aba5 128 Gene3D G3DSA:3.40.1260.10 1 128 2.7E-31 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS17880 832ff651a910cda1590a0fc26ef4aba5 128 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 2 128 2.4E-55 T 10-03-2017 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 RG49_RS17880 832ff651a910cda1590a0fc26ef4aba5 128 SUPERFAMILY SSF75169 1 128 8.83E-39 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS17880 832ff651a910cda1590a0fc26ef4aba5 128 Pfam PF02635 DsrE/DsrF-like family 1 128 3.9E-30 T 10-03-2017 IPR003787 Sulphur relay, DsrE/F-like protein RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 Pfam PF00210 Ferritin-like domain 31 166 5.5E-22 T 10-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 Hamap MF_01441 DNA protection during starvation protein [dps]. 1 167 50.452 T 10-03-2017 IPR023067 DNA protection during starvation protein, gammaproteobacteria GO:0016722|GO:0055114 RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 ProSitePatterns PS00819 Dps protein family signature 2. 77 91 - T 10-03-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 PIRSF PIRSF005900 8 167 2.3E-43 T 10-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 ProSitePatterns PS00818 Dps protein family signature 1. 51 67 - T 10-03-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 Gene3D G3DSA:1.20.1260.10 2 167 1.4E-53 T 10-03-2017 IPR012347 Ferritin-related RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 SUPERFAMILY SSF47240 10 167 5.13E-50 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 1.9E-13 T 10-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 75 91 1.9E-13 T 10-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 RG49_RS06950 36aa46c3c11c46dd41f216524ccbb299 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 144 162 1.9E-13 T 10-03-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 RG49_RS03975 fc1e8d51ffb06a57cec6c6ce903f5e40 350 SUPERFAMILY SSF51735 136 285 3.29E-33 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03975 fc1e8d51ffb06a57cec6c6ce903f5e40 350 SUPERFAMILY SSF50129 1 167 1.16E-11 T 10-03-2017 IPR011032 GroES-like RG49_RS03975 fc1e8d51ffb06a57cec6c6ce903f5e40 350 Gene3D G3DSA:3.90.180.10 1 92 1.4E-4 T 10-03-2017 IPR011032 GroES-like RG49_RS03975 fc1e8d51ffb06a57cec6c6ce903f5e40 350 Pfam PF00107 Zinc-binding dehydrogenase 168 282 6.0E-26 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS03975 fc1e8d51ffb06a57cec6c6ce903f5e40 350 Gene3D G3DSA:3.90.180.10 93 161 3.9E-12 T 10-03-2017 IPR011032 GroES-like RG49_RS03975 fc1e8d51ffb06a57cec6c6ce903f5e40 350 Gene3D G3DSA:3.40.50.720 162 281 1.6E-31 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 SMART SM00849 34 210 1.1E-28 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 PIRSF PIRSF005243 1 399 4.2E-163 T 10-03-2017 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 Gene3D G3DSA:3.40.50.360 249 394 1.9E-51 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 Gene3D G3DSA:2.20.28.10 425 473 3.6E-21 T 10-03-2017 IPR004039 Rubredoxin-type fold RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 SUPERFAMILY SSF57802 425 474 3.87E-18 T 10-03-2017 RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 SUPERFAMILY SSF52218 251 396 7.58E-35 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 PRINTS PR00163 Rubredoxin signature 425 441 5.8E-7 T 10-03-2017 IPR024935 Rubredoxin domain GO:0005506 RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 PRINTS PR00163 Rubredoxin signature 455 471 5.8E-7 T 10-03-2017 IPR024935 Rubredoxin domain GO:0005506 RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 Pfam PF00753 Metallo-beta-lactamase superfamily 34 172 3.5E-11 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 Pfam PF00301 Rubredoxin 425 471 7.9E-21 T 10-03-2017 IPR024935 Rubredoxin domain GO:0005506 RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 SUPERFAMILY SSF56281 8 285 2.23E-51 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 Gene3D G3DSA:3.60.15.10 4 246 6.4E-91 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 Pfam PF00258 Flavodoxin 256 388 1.7E-12 T 10-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 RG49_RS21535 ed0d91155a8967d66eb1c2e60792bf86 479 Hamap MF_01312 Anaerobic nitric oxide reductase flavorubredoxin [norV]. 1 475 93.87 T 10-03-2017 IPR023957 Anaerobic nitric oxide reductase flavorubredoxin GO:0005506|GO:0016966 RG49_RS21905 f3765cb79be94eb6bb9be6d18594558c 166 Pfam PF04606 Ogr/Delta-like zinc finger 87 132 3.8E-9 T 10-03-2017 IPR007684 Zinc finger, Ogr/Delta-type RG49_RS21905 f3765cb79be94eb6bb9be6d18594558c 166 Pfam PF04606 Ogr/Delta-like zinc finger 4 45 1.3E-9 T 10-03-2017 IPR007684 Zinc finger, Ogr/Delta-type RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 Pfam PF03150 Di-haem cytochrome c peroxidase 185 332 1.1E-47 T 10-03-2017 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 Gene3D G3DSA:1.10.760.10 337 460 3.4E-20 T 10-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 Gene3D G3DSA:1.10.760.10 174 336 3.8E-51 T 10-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 Pfam PF00034 Cytochrome c 340 453 3.4E-7 T 10-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 SMART SM01235 16 155 4.8E-54 T 10-03-2017 IPR025992 Haem-binding domain RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 SUPERFAMILY SSF46626 170 320 1.35E-46 T 10-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 Pfam PF14376 Haem-binding domain 18 152 7.3E-34 T 10-03-2017 IPR025992 Haem-binding domain RG49_RS16940 95804d582c3fa91c2361e84073f42252 465 SUPERFAMILY SSF46626 319 460 4.44E-40 T 10-03-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 RG49_RS19905 ce2d33869ccc14c6323baaa2a3d5e0cc 350 SUPERFAMILY SSF55103 193 348 4.91E-14 T 10-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 RG49_RS19905 ce2d33869ccc14c6323baaa2a3d5e0cc 350 Pfam PF01565 FAD binding domain 13 136 4.6E-17 T 10-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 RG49_RS19905 ce2d33869ccc14c6323baaa2a3d5e0cc 350 SUPERFAMILY SSF56176 12 174 3.27E-30 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS19905 ce2d33869ccc14c6323baaa2a3d5e0cc 350 Gene3D G3DSA:3.30.465.10 53 174 6.7E-21 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS19905 ce2d33869ccc14c6323baaa2a3d5e0cc 350 Gene3D G3DSA:1.10.45.10 324 346 9.1E-5 T 10-03-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 263 276 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 Pfam PF00294 pfkB family carbohydrate kinase 17 306 7.5E-54 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 Gene3D G3DSA:3.40.1190.20 19 317 1.7E-54 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 53 77 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 SUPERFAMILY SSF53613 18 312 1.71E-52 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 PRINTS PR00990 Ribokinase signature 21 42 2.4E-5 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 PRINTS PR00990 Ribokinase signature 48 67 2.4E-5 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 PRINTS PR00990 Ribokinase signature 234 245 2.4E-5 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS24685 e0f9ca9e5d1750197efc619d0a4fbdc1 321 PRINTS PR00990 Ribokinase signature 191 206 2.4E-5 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 SMART SM00382 344 514 4.3E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 SMART SM00382 28 230 7.5E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 SUPERFAMILY SSF52540 311 501 6.33E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 SUPERFAMILY SSF52540 9 239 2.04E-50 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 Pfam PF16326 ABC transporter C-terminal domain 561 630 3.1E-21 T 10-03-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 Gene3D G3DSA:3.40.50.300 318 556 1.8E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 Gene3D G3DSA:3.40.50.300 2 270 1.7E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 Pfam PF00005 ABC transporter 336 469 1.7E-24 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 Pfam PF00005 ABC transporter 19 185 1.9E-22 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS05975 742d2f6c2765fa66d4f2849938438877 635 Pfam PF12848 ABC transporter 224 294 1.1E-11 T 10-03-2017 IPR032781 ABC-transporter extension domain RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 46 447 2.0E-186 T 10-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 Gene3D G3DSA:3.40.710.10 227 455 2.8E-67 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 SUPERFAMILY SSF56601 23 473 1.13E-100 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 58 77 5.6E-39 T 10-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 360 374 5.6E-39 T 10-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 424 437 5.6E-39 T 10-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 345 359 5.6E-39 T 10-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 286 308 5.6E-39 T 10-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS18730 859c13d4bf76a7de02832a5f905d1f92 477 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 20 468 2.3E-178 T 10-03-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 10-03-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 265 54.75 T 10-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 11 264 5.4E-90 T 10-03-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 SMART SM00650 25 198 1.7E-84 T 10-03-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 SUPERFAMILY SSF53335 17 266 4.83E-76 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 Gene3D G3DSA:1.10.8.100 201 266 1.5E-25 T 10-03-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 Gene3D G3DSA:3.40.50.150 6 198 1.2E-66 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS11610 2515d982c79f8d998293c1777b6b4314 273 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 265 3.1E-89 T 10-03-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm RG49_RS03485 74101bc33104b8f8cf019df3d9166aa5 61 ProDom PD052969 LIPOPROTEIN PRECURSOR SIGNAL YNBE MEMBRANE OUTER POSSIBLE SIMILAR ECS2004 SO2063 14 61 5.0E-21 T 10-03-2017 RG49_RS03485 74101bc33104b8f8cf019df3d9166aa5 61 Pfam PF13617 YnbE-like lipoprotein 5 59 7.8E-28 T 10-03-2017 IPR025985 YnbE-like lipoprotein RG49_RS14425 aa5259f56846288964836cad322a85dc 810 Gene3D G3DSA:3.40.50.720 457 628 1.8E-54 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14425 aa5259f56846288964836cad322a85dc 810 Pfam PF00696 Amino acid kinase family 12 284 1.7E-43 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS14425 aa5259f56846288964836cad322a85dc 810 SUPERFAMILY SSF51735 457 630 3.55E-34 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14425 aa5259f56846288964836cad322a85dc 810 Gene3D G3DSA:3.40.1160.10 12 59 2.1E-47 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS14425 aa5259f56846288964836cad322a85dc 810 Gene3D G3DSA:3.40.1160.10 114 298 2.1E-47 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS14425 aa5259f56846288964836cad322a85dc 810 SUPERFAMILY SSF53633 12 299 3.4E-56 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS14425 aa5259f56846288964836cad322a85dc 810 SUPERFAMILY SSF55347 608 791 2.55E-48 T 10-03-2017 RG49_RS14425 aa5259f56846288964836cad322a85dc 810 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 465 600 8.3E-27 T 10-03-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 RG49_RS14425 aa5259f56846288964836cad322a85dc 810 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 654 676 - T 10-03-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 RG49_RS14425 aa5259f56846288964836cad322a85dc 810 Pfam PF00742 Homoserine dehydrogenase 608 803 2.0E-45 T 10-03-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 RG49_RS14425 aa5259f56846288964836cad322a85dc 810 PIRSF PIRSF000727 12 810 2.5E-304 T 10-03-2017 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS14425 aa5259f56846288964836cad322a85dc 810 ProSitePatterns PS00324 Aspartokinase signature. 14 22 - T 10-03-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS14425 aa5259f56846288964836cad322a85dc 810 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 15 453 3.9E-63 T 10-03-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS14425 aa5259f56846288964836cad322a85dc 810 Gene3D G3DSA:3.30.360.10 629 786 2.1E-53 T 10-03-2017 RG49_RS07010 2d104461a69ff3e06333a7425b9ff25c 88 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 39 63 - T 10-03-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site RG49_RS07010 2d104461a69ff3e06333a7425b9ff25c 88 PRINTS PR00618 DksA/TraR zinc finger signature 39 50 1.5E-6 T 10-03-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria RG49_RS07010 2d104461a69ff3e06333a7425b9ff25c 88 PRINTS PR00618 DksA/TraR zinc finger signature 51 63 1.5E-6 T 10-03-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria RG49_RS07010 2d104461a69ff3e06333a7425b9ff25c 88 SUPERFAMILY SSF57716 39 72 2.57E-8 T 10-03-2017 RG49_RS07010 2d104461a69ff3e06333a7425b9ff25c 88 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 38 67 1.7E-12 T 10-03-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 RG49_RS08215 22720fdf356cc0c593ed7b8c517ff79f 400 Pfam PF00756 Putative esterase 172 391 9.2E-50 T 10-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 RG49_RS08215 22720fdf356cc0c593ed7b8c517ff79f 400 SUPERFAMILY SSF81296 5 150 8.96E-53 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS08215 22720fdf356cc0c593ed7b8c517ff79f 400 Pfam PF11806 Domain of unknown function (DUF3327) 29 155 1.7E-43 T 10-03-2017 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 RG49_RS08215 22720fdf356cc0c593ed7b8c517ff79f 400 Gene3D G3DSA:2.60.40.10 3 144 1.0E-59 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS08215 22720fdf356cc0c593ed7b8c517ff79f 400 SUPERFAMILY SSF53474 155 393 1.42E-47 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS08215 22720fdf356cc0c593ed7b8c517ff79f 400 Gene3D G3DSA:3.40.50.1820 146 395 2.8E-70 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS23205 ffdb15eded2cbc4a89b6e9ece42b30e9 108 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 6 90 5.7E-27 T 10-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 RG49_RS23205 ffdb15eded2cbc4a89b6e9ece42b30e9 108 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 7 98 2.1E-17 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS23205 ffdb15eded2cbc4a89b6e9ece42b30e9 108 SUPERFAMILY SSF52794 4 101 1.2E-29 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS23205 ffdb15eded2cbc4a89b6e9ece42b30e9 108 Gene3D G3DSA:3.40.50.2300 2 102 8.0E-36 T 10-03-2017 RG49_RS11845 63b2b9981606a9a665dd3ce7bf59dfa4 317 Hamap MF_00492 Transaldolase [tal]. 2 317 52.554 T 10-03-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS11845 63b2b9981606a9a665dd3ce7bf59dfa4 317 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS11845 63b2b9981606a9a665dd3ce7bf59dfa4 317 Gene3D G3DSA:3.20.20.70 3 315 5.6E-134 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS11845 63b2b9981606a9a665dd3ce7bf59dfa4 317 TIGRFAM TIGR00874 talAB: transaldolase 4 316 2.0E-167 T 10-03-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS11845 63b2b9981606a9a665dd3ce7bf59dfa4 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS11845 63b2b9981606a9a665dd3ce7bf59dfa4 317 Pfam PF00923 Transaldolase 14 313 1.2E-102 T 10-03-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS11845 63b2b9981606a9a665dd3ce7bf59dfa4 317 SUPERFAMILY SSF51569 1 316 1.14E-117 T 10-03-2017 RG49_RS17465 8520236d05a6afc2774df1b44cc8a47f 408 SUPERFAMILY SSF103365 7 408 3.27E-142 T 10-03-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 RG49_RS17465 8520236d05a6afc2774df1b44cc8a47f 408 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 29 58 - T 10-03-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 RG49_RS17465 8520236d05a6afc2774df1b44cc8a47f 408 Pfam PF01139 tRNA-splicing ligase RtcB 29 408 1.2E-138 T 10-03-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 RG49_RS12040 83722abbd2c1624977811e7fd00205c6 357 Gene3D G3DSA:3.40.1090.10 27 196 4.6E-7 T 10-03-2017 RG49_RS12040 83722abbd2c1624977811e7fd00205c6 357 SUPERFAMILY SSF52151 21 279 4.45E-43 T 10-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 RG49_RS12040 83722abbd2c1624977811e7fd00205c6 357 Pfam PF01734 Patatin-like phospholipase 27 195 8.7E-21 T 10-03-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 RG49_RS01535 76d7ec9a071eed255b8864d1b7ede0c3 254 SUPERFAMILY SSF52402 1 250 3.42E-55 T 10-03-2017 RG49_RS01535 76d7ec9a071eed255b8864d1b7ede0c3 254 Gene3D G3DSA:3.40.50.620 1 251 5.0E-64 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS01535 76d7ec9a071eed255b8864d1b7ede0c3 254 PIRSF PIRSF000090 1 254 9.5E-65 T 10-03-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 RG49_RS01535 76d7ec9a071eed255b8864d1b7ede0c3 254 Pfam PF01012 Electron transfer flavoprotein domain 28 206 3.1E-37 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS01535 76d7ec9a071eed255b8864d1b7ede0c3 254 SMART SM00893 21 211 4.1E-36 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS01535 76d7ec9a071eed255b8864d1b7ede0c3 254 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 10-03-2017 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 Gene3D G3DSA:1.20.58.180 215 298 5.4E-37 T 10-03-2017 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 8 301 2.3E-178 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 SUPERFAMILY SSF55681 8 292 2.61E-134 T 10-03-2017 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 293 62.833 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 4.1E-71 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 4.1E-71 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 4.1E-71 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 4.1E-71 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 4.1E-71 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 4.1E-71 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 Gene3D G3DSA:3.30.930.10 4 213 9.5E-107 T 10-03-2017 RG49_RS16680 2455e392b06fb0d63a60f5dde5dbac53 303 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 291 5.5E-150 T 10-03-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 172 199 - T 10-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 SUPERFAMILY SSF50129 2 184 2.89E-44 T 10-03-2017 IPR011032 GroES-like RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 Gene3D G3DSA:3.90.180.10 3 188 3.2E-60 T 10-03-2017 IPR011032 GroES-like RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 SUPERFAMILY SSF51735 142 305 2.53E-37 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 Pfam PF00107 Zinc-binding dehydrogenase 179 301 9.5E-22 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 SMART SM00829 13 335 2.3E-6 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 Gene3D G3DSA:3.40.50.720 189 289 7.7E-15 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12570 b5f02cef701c4a2835c4c5c2b59c0900 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 137 2.3E-26 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS14535 37cc44e310531f01ba4bb7cee5d65c85 255 SUPERFAMILY SSF51351 1 248 3.4E-91 T 10-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS14535 37cc44e310531f01ba4bb7cee5d65c85 255 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.5E-108 T 10-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS14535 37cc44e310531f01ba4bb7cee5d65c85 255 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 40.72 T 10-03-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS14535 37cc44e310531f01ba4bb7cee5d65c85 255 Pfam PF00121 Triosephosphate isomerase 5 246 2.5E-93 T 10-03-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS14535 37cc44e310531f01ba4bb7cee5d65c85 255 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 10-03-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS14535 37cc44e310531f01ba4bb7cee5d65c85 255 Gene3D G3DSA:3.20.20.70 1 250 2.0E-102 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS00505 2743f67b48ad68f4b8bd3b756683bfac 214 Gene3D G3DSA:1.10.287.500 35 167 3.8E-56 T 10-03-2017 RG49_RS00505 2743f67b48ad68f4b8bd3b756683bfac 214 Gene3D G3DSA:1.20.5.590 1 34 2.5E-23 T 10-03-2017 RG49_RS00505 2743f67b48ad68f4b8bd3b756683bfac 214 PIRSF PIRSF002884 2 214 6.6E-89 T 10-03-2017 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 RG49_RS00505 2743f67b48ad68f4b8bd3b756683bfac 214 SUPERFAMILY SSF75708 11 213 1.12E-66 T 10-03-2017 RG49_RS00505 2743f67b48ad68f4b8bd3b756683bfac 214 Pfam PF04344 Chemotaxis phosphatase, CheZ 17 214 2.4E-77 T 10-03-2017 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 RG49_RS11720 477b9c5524c33d67a7dbcfd11db76cfc 304 Hamap MF_01432 Non-specific ribonucleoside hydrolase RihC [rihC]. 1 304 80.468 T 10-03-2017 IPR022976 Non-specific ribonucleoside hydrolase RihC GO:0016798 RG49_RS11720 477b9c5524c33d67a7dbcfd11db76cfc 304 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 10-03-2017 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 RG49_RS11720 477b9c5524c33d67a7dbcfd11db76cfc 304 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 293 6.3E-70 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS11720 477b9c5524c33d67a7dbcfd11db76cfc 304 Gene3D G3DSA:3.90.245.10 3 301 1.9E-102 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS11720 477b9c5524c33d67a7dbcfd11db76cfc 304 SUPERFAMILY SSF53590 3 300 5.62E-96 T 10-03-2017 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain RG49_RS00445 14f7eb7f7e7e29a2b88b0781b0dae385 142 PIRSF PIRSF006276 1 141 4.4E-45 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS00445 14f7eb7f7e7e29a2b88b0781b0dae385 142 Gene3D G3DSA:3.40.50.620 3 138 5.8E-25 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS00445 14f7eb7f7e7e29a2b88b0781b0dae385 142 Pfam PF00582 Universal stress protein family 3 138 2.9E-16 T 10-03-2017 IPR006016 UspA GO:0006950 RG49_RS00445 14f7eb7f7e7e29a2b88b0781b0dae385 142 SUPERFAMILY SSF52402 3 138 1.17E-24 T 10-03-2017 RG49_RS15000 ca4acf2e96d03806661ad881a667621e 171 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 143 19.479 T 10-03-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 RG49_RS15000 ca4acf2e96d03806661ad881a667621e 171 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 80 6.2E-32 T 10-03-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 RG49_RS15000 ca4acf2e96d03806661ad881a667621e 171 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.3E-33 T 10-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 RG49_RS15000 ca4acf2e96d03806661ad881a667621e 171 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.3E-33 T 10-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 RG49_RS15000 ca4acf2e96d03806661ad881a667621e 171 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.3E-33 T 10-03-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 RG49_RS07610 4926094861e21986559455693c9fac74 682 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 2 677 0.0 T 10-03-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 RG49_RS07610 4926094861e21986559455693c9fac74 682 Pfam PF00122 E1-E2 ATPase 72 296 3.9E-41 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS07610 4926094861e21986559455693c9fac74 682 Gene3D G3DSA:3.40.1110.10 316 443 6.0E-56 T 10-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 RG49_RS07610 4926094861e21986559455693c9fac74 682 Pfam PF00702 haloacid dehalogenase-like hydrolase 301 530 2.0E-38 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 Gene3D G3DSA:3.40.50.1000 444 563 3.9E-35 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07610 4926094861e21986559455693c9fac74 682 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 372 604 2.0E-49 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS07610 4926094861e21986559455693c9fac74 682 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 72 337 5.8E-38 T 10-03-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF81660 316 450 1.57E-38 T 10-03-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 RG49_RS07610 4926094861e21986559455693c9fac74 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 154 168 3.7E-24 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 551 3.7E-24 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 473 3.7E-24 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 305 319 3.7E-24 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 516 535 3.7E-24 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF81653 120 207 1.44E-20 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 680 41.536 T 10-03-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 RG49_RS07610 4926094861e21986559455693c9fac74 682 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 307 313 - T 10-03-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF81665 29 103 1.7E-12 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF81665 619 661 1.7E-12 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF81665 208 299 1.7E-12 T 10-03-2017 RG49_RS07610 4926094861e21986559455693c9fac74 682 Gene3D G3DSA:2.70.150.10 50 208 7.4E-23 T 10-03-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF56784 293 317 6.28E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF56784 377 404 6.28E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07610 4926094861e21986559455693c9fac74 682 SUPERFAMILY SSF56784 435 559 6.28E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS11420 9fc6a2249ccf26d2a5dd645ebb3f5e85 360 Pfam PF00953 Glycosyl transferase family 4 99 284 9.0E-34 T 10-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 RG49_RS11420 9fc6a2249ccf26d2a5dd645ebb3f5e85 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 25.847 T 10-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11420 9fc6a2249ccf26d2a5dd645ebb3f5e85 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 1.0E-5 T 10-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11420 9fc6a2249ccf26d2a5dd645ebb3f5e85 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 10-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11420 9fc6a2249ccf26d2a5dd645ebb3f5e85 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 6.4E-163 T 10-03-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11420 9fc6a2249ccf26d2a5dd645ebb3f5e85 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 10-03-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS00425 b70200264eed42e487d381444d3b9911 504 Gene3D G3DSA:3.40.50.300 3 230 1.2E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00425 b70200264eed42e487d381444d3b9911 504 SUPERFAMILY SSF52540 6 230 3.59E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00425 b70200264eed42e487d381444d3b9911 504 SMART SM00382 32 220 2.3E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS00425 b70200264eed42e487d381444d3b9911 504 SMART SM00382 281 476 1.6E-5 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS00425 b70200264eed42e487d381444d3b9911 504 SUPERFAMILY SSF52540 274 484 4.95E-42 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00425 b70200264eed42e487d381444d3b9911 504 Gene3D G3DSA:3.40.50.300 274 491 7.3E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00425 b70200264eed42e487d381444d3b9911 504 Pfam PF00005 ABC transporter 275 427 1.4E-17 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS00425 b70200264eed42e487d381444d3b9911 504 Pfam PF00005 ABC transporter 23 172 1.3E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS00425 b70200264eed42e487d381444d3b9911 504 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24590 8c47782bc490b8c80f34fd0d52d0b9ba 362 Gene3D G3DSA:3.40.50.300 65 236 1.1E-18 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24590 8c47782bc490b8c80f34fd0d52d0b9ba 362 SMART SM00382 75 230 0.0015 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24590 8c47782bc490b8c80f34fd0d52d0b9ba 362 Pfam PF07728 AAA domain (dynein-related subfamily) 79 220 3.7E-33 T 10-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 RG49_RS24590 8c47782bc490b8c80f34fd0d52d0b9ba 362 SUPERFAMILY SSF52540 56 331 8.04E-23 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 61.095 T 10-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 Gene3D G3DSA:2.40.30.10 209 298 2.7E-37 T 10-03-2017 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 1.6E-14 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 7.1E-58 T 10-03-2017 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 Gene3D G3DSA:3.40.50.300 3 208 5.3E-68 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 7.8E-18 T 10-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 SUPERFAMILY SSF50465 298 393 2.76E-36 T 10-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 SUPERFAMILY SSF50447 205 301 1.34E-30 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 393 1.0E-239 T 10-03-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 SUPERFAMILY SSF52540 6 219 1.94E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-24 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 Gene3D G3DSA:2.40.30.10 300 393 8.4E-47 T 10-03-2017 RG49_RS17910 d97d0bb0b8c4c3f565cdc0812427d908 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 9.5E-34 T 10-03-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 243 6.7E-41 T 10-03-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 Gene3D G3DSA:3.10.150.10 249 366 4.9E-39 T 10-03-2017 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 SUPERFAMILY SSF55979 1 121 5.84E-26 T 10-03-2017 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 Gene3D G3DSA:3.10.150.10 122 248 1.2E-38 T 10-03-2017 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 PIRSF PIRSF000804 1 366 7.2E-119 T 10-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 SMART SM00480 17 362 8.4E-176 T 10-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 3.0E-114 T 10-03-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 365 1.3E-45 T 10-03-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 SUPERFAMILY SSF55979 125 244 5.5E-30 T 10-03-2017 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 SUPERFAMILY SSF55979 245 366 6.77E-38 T 10-03-2017 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 7.9E-41 T 10-03-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS15720 b8c84d6f36a917c175c68a7edb9861d4 366 Gene3D G3DSA:3.10.150.10 1 121 1.3E-32 T 10-03-2017 RG49_RS19695 d24c523a8ef4db91a35a85a55ac2da72 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS19695 d24c523a8ef4db91a35a85a55ac2da72 387 Gene3D G3DSA:1.20.1090.10 185 386 1.8E-56 T 10-03-2017 RG49_RS19695 d24c523a8ef4db91a35a85a55ac2da72 387 Gene3D G3DSA:3.40.50.1970 1 184 6.2E-56 T 10-03-2017 RG49_RS19695 d24c523a8ef4db91a35a85a55ac2da72 387 SUPERFAMILY SSF56796 1 385 7.07E-109 T 10-03-2017 RG49_RS19695 d24c523a8ef4db91a35a85a55ac2da72 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS19695 d24c523a8ef4db91a35a85a55ac2da72 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 360 1.1E-92 T 10-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 Gene3D G3DSA:3.40.50.720 401 470 5.4E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 Gene3D G3DSA:3.40.50.720 150 236 5.4E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 459 9.4E-26 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 Gene3D G3DSA:3.50.50.60 237 400 4.0E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 SUPERFAMILY SSF51971 145 401 7.06E-70 T 10-03-2017 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 6 472 2.2E-271 T 10-03-2017 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 SUPERFAMILY SSF46548 7 157 1.1E-41 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 PRINTS PR00419 Adrenodoxin reductase family signature 324 337 4.8E-38 T 10-03-2017 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 4.8E-38 T 10-03-2017 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 PRINTS PR00419 Adrenodoxin reductase family signature 290 304 4.8E-38 T 10-03-2017 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 4.8E-38 T 10-03-2017 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 4.8E-38 T 10-03-2017 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 134 5.8E-38 T 10-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 RG49_RS18565 5af2fdc9ce6e4da36f79f1557c99fa94 472 Gene3D G3DSA:1.10.1060.10 5 149 8.8E-48 T 10-03-2017 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 SMART SM00278 73 92 1.3 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 SMART SM00278 108 127 0.05 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 203 5.0E-74 T 10-03-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 SUPERFAMILY SSF50249 2 63 7.42E-19 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 SUPERFAMILY SSF46929 157 201 7.59E-11 T 10-03-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 Gene3D G3DSA:2.40.50.140 2 64 1.5E-27 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 203 32.86 T 10-03-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 SUPERFAMILY SSF47781 66 137 9.18E-22 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 Gene3D G3DSA:1.10.8.10 157 200 2.4E-23 T 10-03-2017 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 Gene3D G3DSA:1.10.150.20 67 138 3.2E-31 T 10-03-2017 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 Pfam PF01330 RuvA N terminal domain 2 62 4.3E-20 T 10-03-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 Pfam PF14520 Helix-hairpin-helix domain 72 130 3.4E-16 T 10-03-2017 RG49_RS00615 6dea786b6f8d6b227aab6944d807fc31 203 Pfam PF07499 RuvA, C-terminal domain 159 201 2.3E-15 T 10-03-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 RG49_RS07380 b9f03a52e78ffa0c5f3d4d4301c34388 379 PIRSF PIRSF000267 2 378 6.5E-137 T 10-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 RG49_RS07380 b9f03a52e78ffa0c5f3d4d4301c34388 379 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 362 7.5E-112 T 10-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 RG49_RS07380 b9f03a52e78ffa0c5f3d4d4301c34388 379 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 379 3.9E-210 T 10-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 RG49_RS14985 715f6a36cd2c3556526a6e82f0038c29 162 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 1 162 48.194 T 10-03-2017 IPR010215 Transcription antitermination protein RfaH GO:0006355 RG49_RS14985 715f6a36cd2c3556526a6e82f0038c29 162 Gene3D G3DSA:2.30.30.30 112 138 8.5E-4 T 10-03-2017 IPR014722 Ribosomal protein L2 domain 2 RG49_RS14985 715f6a36cd2c3556526a6e82f0038c29 162 SMART SM00738 1 100 1.1E-33 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS14985 715f6a36cd2c3556526a6e82f0038c29 162 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 4 159 3.6E-70 T 10-03-2017 IPR010215 Transcription antitermination protein RfaH GO:0006355 RG49_RS14985 715f6a36cd2c3556526a6e82f0038c29 162 Pfam PF02357 Transcription termination factor nusG 3 96 1.2E-19 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS14985 715f6a36cd2c3556526a6e82f0038c29 162 SUPERFAMILY SSF82679 1 96 1.26E-27 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS14985 715f6a36cd2c3556526a6e82f0038c29 162 Gene3D G3DSA:3.30.70.940 2 96 4.5E-17 T 10-03-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 Gene3D G3DSA:3.40.50.300 189 384 6.5E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 Gene3D G3DSA:3.30.230.10 5 166 1.5E-25 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 Pfam PF01078 Magnesium chelatase, subunit ChlI 189 386 1.9E-89 T 10-03-2017 IPR000523 Magnesium chelatase ChlI domain RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 SUPERFAMILY SSF52540 188 503 5.74E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 492 8.6E-252 T 10-03-2017 IPR004482 Mg chelatase-related protein RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 2.1E-44 T 10-03-2017 RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 SMART SM00382 209 389 3.0E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 SUPERFAMILY SSF54211 11 169 8.72E-29 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS15385 a05c0a7c588cb3e3f60c9530c5aa4e64 506 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 400 492 2.3E-29 T 10-03-2017 IPR025158 Mg chelatase-related protein, C-terminal domain RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 597 614 - T 10-03-2017 IPR010917 TonB-dependent receptor, conserved site RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 SUPERFAMILY SSF56935 26 614 7.02E-128 T 10-03-2017 RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 Hamap MF_01531 Vitamin B12 transporter BtuB [btuB]. 2 614 35.971 T 10-03-2017 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 Gene3D G3DSA:2.40.170.20 153 614 4.7E-101 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 Pfam PF00593 TonB dependent receptor 390 613 2.4E-32 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 Pfam PF07715 TonB-dependent Receptor Plug Domain 41 146 1.0E-29 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 Gene3D G3DSA:2.170.130.10 20 152 7.8E-42 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 TIGRFAM TIGR01779 TonB-B12: TonB-dependent vitamin B12 receptor 2 614 2.3E-272 T 10-03-2017 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 RG49_RS14275 bff682d892bd20567c21bf5a41df7872 614 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 33 - T 10-03-2017 IPR010916 TonB box, conserved site RG49_RS08070 e12fa98a49523be028e9ff30aee67f2c 136 Pfam PF14760 Rnk N-terminus 4 42 1.7E-10 T 10-03-2017 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain RG49_RS08070 e12fa98a49523be028e9ff30aee67f2c 136 SUPERFAMILY SSF54534 49 127 1.96E-18 T 10-03-2017 RG49_RS08070 e12fa98a49523be028e9ff30aee67f2c 136 Gene3D G3DSA:3.10.50.30 46 135 4.4E-30 T 10-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 RG49_RS08070 e12fa98a49523be028e9ff30aee67f2c 136 Gene3D G3DSA:1.10.286.20 1 44 1.7E-22 T 10-03-2017 RG49_RS08070 e12fa98a49523be028e9ff30aee67f2c 136 Hamap MF_00954 Regulator of nucleoside diphosphate kinase [rnk]. 1 136 43.797 T 10-03-2017 IPR028625 Regulator of nucleoside diphosphate kinase GO:0065007|GO:0070063 RG49_RS08070 e12fa98a49523be028e9ff30aee67f2c 136 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 50 126 1.9E-20 T 10-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 RG49_RS06760 41a432b4b84625f96b6391b2fa3ffe76 189 Pfam PF07022 Bacteriophage CI repressor helix-turn-helix domain 9 72 4.9E-31 T 10-03-2017 IPR010744 Bacteriophage CI repressor GO:0003677|GO:0045892 RG49_RS06760 41a432b4b84625f96b6391b2fa3ffe76 189 Pfam PF16452 Bacteriophage CI repressor C-terminal domain 82 181 5.1E-30 T 10-03-2017 IPR032499 Bacteriophage CI repressor, C-terminal GO:0051259 RG49_RS08130 ef8121bd7f52b806d5a10c194daf301a 362 Gene3D G3DSA:3.40.50.1970 6 160 6.8E-34 T 10-03-2017 RG49_RS08130 ef8121bd7f52b806d5a10c194daf301a 362 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 152 180 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS08130 ef8121bd7f52b806d5a10c194daf301a 362 Gene3D G3DSA:1.20.1090.10 162 359 4.8E-52 T 10-03-2017 RG49_RS08130 ef8121bd7f52b806d5a10c194daf301a 362 SUPERFAMILY SSF56796 9 357 3.79E-59 T 10-03-2017 RG49_RS08130 ef8121bd7f52b806d5a10c194daf301a 362 PIRSF PIRSF000112 2 362 1.0E-131 T 10-03-2017 RG49_RS08130 ef8121bd7f52b806d5a10c194daf301a 362 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 348 1.1E-46 T 10-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Pfam PF14520 Helix-hairpin-helix domain 557 609 2.4E-8 T 10-03-2017 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Pfam PF02151 UvrB/uvrC motif 205 237 4.8E-10 T 10-03-2017 IPR001943 UVR domain GO:0005515 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 9 589 5.0E-241 T 10-03-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Gene3D G3DSA:1.10.150.20 555 609 3.3E-22 T 10-03-2017 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Pfam PF01541 GIY-YIG catalytic domain 18 93 3.4E-11 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 SUPERFAMILY SSF46600 190 243 3.4E-14 T 10-03-2017 IPR001943 UVR domain GO:0005515 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 607 30.441 T 10-03-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 SUPERFAMILY SSF82771 17 100 3.01E-24 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 SMART SM00465 17 98 2.2E-23 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 386 542 4.0E-45 T 10-03-2017 IPR001162 UvrC family homology region RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Gene3D G3DSA:3.40.1440.10 17 97 2.1E-11 T 10-03-2017 IPR027299 GIY-YIG domain RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 Gene3D G3DSA:4.10.860.10 183 243 1.5E-22 T 10-03-2017 IPR001943 UVR domain GO:0005515 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 SMART SM00278 588 607 2.9 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 SMART SM00278 556 575 0.76 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS00345 461799c9cd3c68da7ff8668881953f7b 610 SUPERFAMILY SSF47781 521 606 2.22E-17 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 Pfam PF04408 Helicase associated domain (HA2) 389 444 2.0E-10 T 10-03-2017 IPR007502 Helicase-associated domain GO:0004386 RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 Pfam PF00270 DEAD/DEAH box helicase 21 163 2.8E-9 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 Pfam PF00271 Helicase conserved C-terminal domain 208 327 6.8E-10 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 SMART SM00487 5 186 1.7E-20 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 SUPERFAMILY SSF52540 12 431 6.04E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 SMART SM00847 388 476 1.4E-12 T 10-03-2017 IPR007502 Helicase-associated domain GO:0004386 RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 SMART SM00490 230 328 6.9E-13 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 Pfam PF08482 ATP-dependent helicase C-terminal 664 796 2.3E-54 T 10-03-2017 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 Gene3D G3DSA:3.40.50.300 184 344 1.9E-14 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 808 0.0 T 10-03-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 Gene3D G3DSA:3.40.50.300 3 160 3.7E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11090 4f7e7fd57709490b6912e58566edabb9 809 PIRSF PIRSF005496 1 809 0.0 T 10-03-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type RG49_RS00680 b314da7703a0f4533abc0e706147208f 213 Pfam PF01081 KDPG and KHG aldolase 9 203 2.0E-94 T 10-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 RG49_RS00680 b314da7703a0f4533abc0e706147208f 213 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 209 3.0E-87 T 10-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 RG49_RS00680 b314da7703a0f4533abc0e706147208f 213 SUPERFAMILY SSF51569 3 209 5.49E-69 T 10-03-2017 RG49_RS00680 b314da7703a0f4533abc0e706147208f 213 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 10-03-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 RG49_RS00680 b314da7703a0f4533abc0e706147208f 213 Gene3D G3DSA:3.20.20.70 2 210 2.9E-78 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS00680 b314da7703a0f4533abc0e706147208f 213 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 40 49 - T 10-03-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 RG49_RS19890 555be2aa7849ea2d16d14c952d8dc806 380 SUPERFAMILY SSF55729 145 377 4.33E-26 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS19890 555be2aa7849ea2d16d14c952d8dc806 380 SUPERFAMILY SSF55729 9 117 4.33E-26 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS19890 555be2aa7849ea2d16d14c952d8dc806 380 Gene3D G3DSA:3.40.630.30 213 374 1.9E-5 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS06985 973cd34b5584760b1badc4f3c7afaa8a 741 SUPERFAMILY SSF82861 477 556 3.66E-12 T 10-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 RG49_RS06985 973cd34b5584760b1badc4f3c7afaa8a 741 Pfam PF00924 Mechanosensitive ion channel 515 714 4.4E-44 T 10-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 RG49_RS06985 973cd34b5584760b1badc4f3c7afaa8a 741 SUPERFAMILY SSF50182 558 616 1.28E-9 T 10-03-2017 IPR010920 LSM domain RG49_RS06985 973cd34b5584760b1badc4f3c7afaa8a 741 Gene3D G3DSA:2.30.30.60 576 616 3.3E-8 T 10-03-2017 RG49_RS06985 973cd34b5584760b1badc4f3c7afaa8a 741 SUPERFAMILY SSF82689 627 722 2.09E-8 T 10-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 RG49_RS03110 da9bc1e6692e701d019079e890bc57f8 205 Gene3D G3DSA:3.40.30.10 2 87 1.3E-12 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS03110 da9bc1e6692e701d019079e890bc57f8 205 Gene3D G3DSA:1.20.1050.10 88 191 3.2E-17 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS03110 da9bc1e6692e701d019079e890bc57f8 205 SUPERFAMILY SSF52833 2 79 2.33E-10 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS03110 da9bc1e6692e701d019079e890bc57f8 205 Pfam PF13417 Glutathione S-transferase, N-terminal domain 17 79 5.3E-6 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS03110 da9bc1e6692e701d019079e890bc57f8 205 SUPERFAMILY SSF47616 79 203 9.38E-17 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Pfam PF00072 Response regulator receiver domain 827 936 2.5E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 581 690 1.5E-28 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Gene3D G3DSA:1.10.287.130 473 520 2.4E-17 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 SMART SM00448 825 936 1.3E-37 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Pfam PF09456 RcsC Alpha-Beta-Loop (ABL) 709 799 1.2E-34 T 10-03-2017 IPR019017 Signal transduction histidine kinase RcsC, alpha-beta loop, C-terminal GO:0000160|GO:0004673|GO:0004871|GO:0005524|GO:0005886|GO:0006355|GO:0016021|GO:0018106 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Gene3D G3DSA:3.30.565.10 521 693 3.9E-47 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 SUPERFAMILY SSF52172 824 947 3.27E-38 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 SMART SM00388 469 534 1.7E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 SUPERFAMILY SSF47384 453 535 2.16E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 SMART SM00387 581 692 2.8E-38 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Pfam PF00512 His Kinase A (phospho-acceptor) domain 469 533 5.1E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Hamap MF_00979 Sensor histidine kinase RcsC [rcsC]. 24 941 27.415 T 10-03-2017 IPR030856 Sensor histidine kinase RcsC GO:0000155|GO:0000160|GO:0016021|GO:0042710 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Gene3D G3DSA:3.40.50.2300 822 945 9.8E-40 T 10-03-2017 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 SUPERFAMILY SSF52172 701 815 2.2E-42 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 SUPERFAMILY SSF55874 523 694 3.8E-48 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 631 4.8E-18 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 645 4.8E-18 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 670 4.8E-18 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 PRINTS PR00344 Bacterial sensor protein C-terminal signature 676 689 4.8E-18 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24020 072ebf24966e628873d0ad9af2f58b63 949 Gene3D G3DSA:3.30.450.20 417 472 1.7E-6 T 10-03-2017 RG49_RS19000 42840e144b6695d5704ba5494f470c33 157 Pfam PF03830 PTS system sorbose subfamily IIB component 4 149 3.2E-50 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS19000 42840e144b6695d5704ba5494f470c33 157 SUPERFAMILY SSF52728 3 156 3.27E-51 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS19000 42840e144b6695d5704ba5494f470c33 157 Gene3D G3DSA:3.40.35.10 3 157 9.3E-58 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS19000 42840e144b6695d5704ba5494f470c33 157 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 3 152 9.1E-74 T 10-03-2017 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 RG49_RS08465 23739e0d7ba81c082008c3a9a94bcc78 169 Pfam PF00731 AIR carboxylase 9 157 7.5E-64 T 10-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 RG49_RS08465 23739e0d7ba81c082008c3a9a94bcc78 169 SMART SM01001 8 159 1.3E-103 T 10-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 RG49_RS08465 23739e0d7ba81c082008c3a9a94bcc78 169 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 10 163 32.41 T 10-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 RG49_RS08465 23739e0d7ba81c082008c3a9a94bcc78 169 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 10 163 2.2E-66 T 10-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 RG49_RS08465 23739e0d7ba81c082008c3a9a94bcc78 169 Gene3D G3DSA:3.40.50.7700 4 163 4.2E-75 T 10-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 RG49_RS08465 23739e0d7ba81c082008c3a9a94bcc78 169 SUPERFAMILY SSF52255 7 165 3.4E-67 T 10-03-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 RG49_RS08465 23739e0d7ba81c082008c3a9a94bcc78 169 PIRSF PIRSF001338 5 166 2.0E-67 T 10-03-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 RG49_RS12330 1d3fc93add9b9ad107f1bbe593b9cf53 286 Gene3D G3DSA:2.120.10.30 54 283 1.4E-13 T 10-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like RG49_RS12330 1d3fc93add9b9ad107f1bbe593b9cf53 286 Pfam PF06977 SdiA-regulated 38 281 6.4E-91 T 10-03-2017 IPR009722 SdiA-regulated RG49_RS12330 1d3fc93add9b9ad107f1bbe593b9cf53 286 SUPERFAMILY SSF50956 15 282 4.05E-38 T 10-03-2017 RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 PIRSF PIRSF001549 2 423 7.0E-131 T 10-03-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 SUPERFAMILY SSF55681 5 318 4.4E-106 T 10-03-2017 RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 Pfam PF13393 Histidyl-tRNA synthetase 10 312 1.2E-47 T 10-03-2017 RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 Gene3D G3DSA:3.40.50.800 328 422 1.2E-32 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 Pfam PF03129 Anticodon binding domain 340 420 4.2E-10 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 Gene3D G3DSA:3.30.930.10 4 185 2.4E-99 T 10-03-2017 RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 Gene3D G3DSA:3.30.930.10 221 320 2.4E-99 T 10-03-2017 RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 411 2.1E-157 T 10-03-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 SUPERFAMILY SSF52954 329 423 3.11E-25 T 10-03-2017 IPR004154 Anticodon-binding RG49_RS22500 187d6e53c5247698ae6efef771c48d0e 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 421 33.833 T 10-03-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 SUPERFAMILY SSF51971 311 565 2.65E-64 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 PRINTS PR00419 Adrenodoxin reductase family signature 454 468 8.2E-36 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 PRINTS PR00419 Adrenodoxin reductase family signature 488 501 8.2E-36 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 PRINTS PR00419 Adrenodoxin reductase family signature 377 387 8.2E-36 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 PRINTS PR00419 Adrenodoxin reductase family signature 312 334 8.2E-36 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 PRINTS PR00419 Adrenodoxin reductase family signature 335 348 8.2E-36 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:3.30.70.20 125 145 5.5E-14 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:3.30.70.20 4 60 5.5E-14 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Pfam PF13247 4Fe-4S dicluster domain 53 136 2.2E-11 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:3.50.50.60 559 631 3.2E-7 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:3.50.50.60 313 409 2.6E-30 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:3.30.70.20 93 124 6.5E-11 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS20475 930da08c17453e19338fb736b5f29514 639 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 171 635 2.5E-256 T 10-03-2017 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 SUPERFAMILY SSF54862 180 274 8.37E-42 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 SUPERFAMILY SSF54862 1 153 8.37E-42 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:1.10.1060.10 173 312 1.2E-40 T 10-03-2017 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 188 298 2.9E-36 T 10-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:3.50.50.60 410 558 4.1E-44 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 312 623 1.2E-20 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20475 930da08c17453e19338fb736b5f29514 639 Gene3D G3DSA:3.30.70.20 61 92 1.8E-13 T 10-03-2017 RG49_RS02030 2fe7a01c87ee3700155ffe01c39a30c1 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 238 3.5E-22 T 10-03-2017 RG49_RS02030 2fe7a01c87ee3700155ffe01c39a30c1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.5E-11 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02030 2fe7a01c87ee3700155ffe01c39a30c1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.5E-11 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02030 2fe7a01c87ee3700155ffe01c39a30c1 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.5E-11 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS02030 2fe7a01c87ee3700155ffe01c39a30c1 240 SUPERFAMILY SSF51735 9 239 2.86E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02030 2fe7a01c87ee3700155ffe01c39a30c1 240 Gene3D G3DSA:3.40.50.720 9 239 2.1E-41 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02030 2fe7a01c87ee3700155ffe01c39a30c1 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 Pfam PF00005 ABC transporter 280 434 1.5E-17 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 Pfam PF00005 ABC transporter 29 178 2.3E-29 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 Gene3D G3DSA:3.40.50.300 11 241 1.5E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 Gene3D G3DSA:3.40.50.300 263 497 9.2E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 SUPERFAMILY SSF52540 12 236 7.84E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 SMART SM00382 38 225 2.0E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 SMART SM00382 288 483 0.68 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24425 ad359524d743b331868d5956ec1fd6d6 506 SUPERFAMILY SSF52540 253 487 2.47E-40 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03705 467ed5fb046d24723860c64664ca6671 93 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 15 66 3.0E-9 T 10-03-2017 IPR031856 Putative bacterial antitoxin YdaS RG49_RS03705 467ed5fb046d24723860c64664ca6671 93 Gene3D G3DSA:1.10.260.40 8 76 2.9E-15 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS00855 cfe71912c616ffe12d5f3ed5caf1d009 206 Pfam PF02659 Putative manganese efflux pump 49 200 1.4E-53 T 10-03-2017 IPR003810 Putative manganese efflux pump RG49_RS00855 cfe71912c616ffe12d5f3ed5caf1d009 206 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 19 203 25.746 T 10-03-2017 IPR022929 Putative manganese efflux pump MntP RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 Gene3D G3DSA:2.40.128.130 142 458 9.0E-79 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 SUPERFAMILY SSF51126 10 112 3.14E-29 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 Gene3D G3DSA:2.160.20.20 9 128 6.1E-40 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 Pfam PF03212 Pertactin 5 111 6.0E-43 T 10-03-2017 IPR004899 Pertactin, central region RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 PRINTS PR01484 Pertactin virulence factor family signature 174 192 1.5E-17 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 PRINTS PR01484 Pertactin virulence factor family signature 194 214 1.5E-17 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 PRINTS PR01484 Pertactin virulence factor family signature 326 343 1.5E-17 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 PRINTS PR01484 Pertactin virulence factor family signature 438 458 1.5E-17 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 PRINTS PR01484 Pertactin virulence factor family signature 345 368 1.5E-17 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 PRINTS PR01484 Pertactin virulence factor family signature 235 259 1.5E-17 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 PRINTS PR01484 Pertactin virulence factor family signature 374 395 1.5E-17 T 10-03-2017 IPR003991 Pertactin virulence factor family GO:0007155 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 SMART SM00869 194 447 8.6E-43 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 SUPERFAMILY SSF103515 162 458 5.75E-51 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 15 458 4.3E-100 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS21855 a3303a7fd59c3d0545ca46022607a4f9 458 Pfam PF03797 Autotransporter beta-domain 192 442 1.3E-48 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 SUPERFAMILY SSF82866 805 1039 7.46E-44 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 Gene3D G3DSA:3.30.2090.10 724 807 3.2E-17 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 Gene3D G3DSA:3.30.2090.10 185 269 8.0E-21 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 SUPERFAMILY SSF82714 723 808 1.28E-16 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 SUPERFAMILY SSF82693 46 126 2.2E-20 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.1E-21 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 1.1E-21 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.1E-21 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 1.1E-21 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 1.1E-21 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.1E-21 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 Gene3D G3DSA:3.30.70.1430 46 141 7.9E-26 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 SUPERFAMILY SSF82714 186 269 4.71E-20 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 Gene3D G3DSA:1.10.3850.10 275 507 6.9E-68 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 Gene3D G3DSA:1.10.3850.10 815 1038 9.1E-49 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 SUPERFAMILY SSF82866 294 506 5.89E-41 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 SUPERFAMILY SSF82693 271 328 1.39E-21 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 SUPERFAMILY SSF82693 137 184 1.39E-21 T 10-03-2017 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 Pfam PF00873 AcrB/AcrD/AcrF family 6 1037 1.4E-238 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08295 92dbcf9a481b2bf5f4dd8dbff085f95f 1047 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1047 0.0 T 10-03-2017 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 SUPERFAMILY SSF49493 256 341 6.02E-21 T 10-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 10-03-2017 IPR018253 DnaJ domain, conserved site RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Pfam PF00684 DnaJ central domain 144 204 3.8E-16 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Pfam PF00226 DnaJ domain 5 67 8.3E-29 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Gene3D G3DSA:2.60.260.20 103 137 3.4E-22 T 10-03-2017 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Gene3D G3DSA:2.60.260.20 207 251 3.4E-22 T 10-03-2017 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Gene3D G3DSA:2.10.230.10 138 206 5.4E-27 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 370 43.067 T 10-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 347 1.1E-143 T 10-03-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 SUPERFAMILY SSF57938 131 207 3.14E-24 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 SUPERFAMILY SSF46565 1 106 9.29E-37 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Pfam PF01556 DnaJ C terminal domain 118 330 1.2E-45 T 10-03-2017 IPR002939 Chaperone DnaJ, C-terminal RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 SMART SM00271 4 62 1.5E-31 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Gene3D G3DSA:2.60.260.20 253 330 3.2E-23 T 10-03-2017 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 Gene3D G3DSA:1.10.287.110 1 102 4.1E-38 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 SUPERFAMILY SSF49493 111 166 2.49E-20 T 10-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 SUPERFAMILY SSF49493 210 256 2.49E-20 T 10-03-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 PRINTS PR00625 DnaJ domain signature 7 25 1.0E-33 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 PRINTS PR00625 DnaJ domain signature 42 62 1.0E-33 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 PRINTS PR00625 DnaJ domain signature 62 81 1.0E-33 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11815 6bd18f18743b5794f931d27923d1c4b0 376 PRINTS PR00625 DnaJ domain signature 25 40 1.0E-33 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 Pfam PF01743 Poly A polymerase head domain 69 200 1.8E-39 T 10-03-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 31 467 38.846 T 10-03-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 Gene3D G3DSA:3.30.460.10 51 199 8.8E-51 T 10-03-2017 RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 Gene3D G3DSA:1.10.3090.10 200 434 7.9E-52 T 10-03-2017 RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 Pfam PF12626 Polymerase A arginine-rich C-terminus 345 463 1.6E-40 T 10-03-2017 IPR025866 Polymerase A arginine-rich C-terminal domain RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 SUPERFAMILY SSF81301 41 196 2.29E-40 T 10-03-2017 RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 SUPERFAMILY SSF81891 198 436 2.22E-52 T 10-03-2017 RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 227 288 1.6E-20 T 10-03-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 RG49_RS11115 02faf989920d9ecf65dd1a483aac0ee4 472 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 38 465 1.5E-157 T 10-03-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 RG49_RS02575 35b1c7934308c66f9597dc4890ca4134 221 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 213 1.1E-36 T 10-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 RG49_RS02575 35b1c7934308c66f9597dc4890ca4134 221 Pfam PF01914 MarC family integral membrane protein 5 217 1.8E-71 T 10-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 RG49_RS05370 153a143fd6ce37de98555a376599e43c 191 Gene3D G3DSA:2.40.128.110 22 190 4.7E-63 T 10-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like RG49_RS05370 153a143fd6ce37de98555a376599e43c 191 SMART SM00867 24 188 7.0E-75 T 10-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like RG49_RS05370 153a143fd6ce37de98555a376599e43c 191 Pfam PF04264 YceI-like domain 25 186 9.9E-44 T 10-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like RG49_RS05370 153a143fd6ce37de98555a376599e43c 191 SUPERFAMILY SSF101874 22 190 4.97E-58 T 10-03-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like RG49_RS05370 153a143fd6ce37de98555a376599e43c 191 Hamap MF_00780 Protein YceI [yceI]. 1 191 49.19 T 10-03-2017 IPR023480 Uncharacterised protein family UPF0312/YceI RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 SUPERFAMILY SSF103473 24 446 1.7E-69 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 SUPERFAMILY SSF103661 465 497 1.83E-12 T 10-03-2017 RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 Gene3D G3DSA:1.20.1250.20 256 444 8.3E-28 T 10-03-2017 RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 Gene3D G3DSA:1.20.1250.20 24 232 4.3E-24 T 10-03-2017 RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 Pfam PF00083 Sugar (and other) transporter 28 448 1.2E-75 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 332 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 Pfam PF08946 Osmosensory transporter coiled coil 454 499 1.2E-22 T 10-03-2017 IPR015041 Osmosensory transporter coiled coil RG49_RS13405 e8a9955531afa3e6aba0093034697cf3 500 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 33 432 3.6E-145 T 10-03-2017 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 SUPERFAMILY SSF56176 6 173 1.69E-51 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 SMART SM01092 181 283 1.7E-25 T 10-03-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 Gene3D G3DSA:3.30.43.10 6 56 2.7E-14 T 10-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 Gene3D G3DSA:3.30.390.50 180 288 5.5E-29 T 10-03-2017 RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 Gene3D G3DSA:3.30.465.10 57 173 3.1E-36 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 283 4.3E-24 T 10-03-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 173 3.3E-51 T 10-03-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 RG49_RS20575 6528f59616cd448ec93bb8144736b039 292 SUPERFAMILY SSF55447 181 284 5.23E-25 T 10-03-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal RG49_RS10695 5bd4f19d4fd192e4ed2d5b0974a6e4f3 1174 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 32 1170 1.8E-283 T 10-03-2017 IPR017731 Type VI secretion system, IcmF RG49_RS10695 5bd4f19d4fd192e4ed2d5b0974a6e4f3 1174 SUPERFAMILY SSF52540 135 295 8.9E-7 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10695 5bd4f19d4fd192e4ed2d5b0974a6e4f3 1174 Gene3D G3DSA:3.40.50.300 140 292 6.6E-4 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10695 5bd4f19d4fd192e4ed2d5b0974a6e4f3 1174 Pfam PF06744 Type VI secretion protein IcmF C-terminal 926 1122 1.5E-51 T 10-03-2017 IPR010623 Type VI secretion system IcmF, C-terminal RG49_RS10695 5bd4f19d4fd192e4ed2d5b0974a6e4f3 1174 Pfam PF06761 Intracellular multiplication and human macrophage-killing 506 818 1.1E-71 T 10-03-2017 IPR009612 ImcF-related RG49_RS10695 5bd4f19d4fd192e4ed2d5b0974a6e4f3 1174 Pfam PF14331 ImcF-related N-terminal domain 205 453 9.4E-62 T 10-03-2017 IPR025743 ImcF-related, N-terminal domain RG49_RS00770 b02f6262d78c1d75c7f7d2332f6959be 78 Pfam PF07351 Protein of unknown function (DUF1480) 2 77 1.5E-37 T 10-03-2017 IPR009950 Protein of unknown function DUF1480 RG49_RS00770 b02f6262d78c1d75c7f7d2332f6959be 78 ProDom PD060427 YEBV CYTOPLASMIC Y1856 ESCHERICHIA ECS2546 YPO1694 COLI STY1982 SIMILAR 1 78 1.0E-40 T 10-03-2017 IPR009950 Protein of unknown function DUF1480 RG49_RS24530 23faa4d315cbc0d67f4e4275ee84e229 385 Gene3D G3DSA:1.10.3720.10 166 367 5.7E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24530 23faa4d315cbc0d67f4e4275ee84e229 385 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 195 375 7.9E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24530 23faa4d315cbc0d67f4e4275ee84e229 385 SUPERFAMILY SSF161098 173 371 1.14E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS21300 46a36735b2709af6d1479523273a7d96 97 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 3 88 7.1E-37 T 10-03-2017 IPR010152 CRISPR-associated protein Cas2 subtype RG49_RS21300 46a36735b2709af6d1479523273a7d96 97 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 3 88 1.2E-39 T 10-03-2017 IPR010152 CRISPR-associated protein Cas2 subtype RG49_RS15455 19be1fe83a694bc8fcd9e001003ab5fe 296 Gene3D G3DSA:3.40.50.2300 27 144 4.1E-44 T 10-03-2017 RG49_RS15455 19be1fe83a694bc8fcd9e001003ab5fe 296 Pfam PF13407 Periplasmic binding protein domain 29 281 2.2E-58 T 10-03-2017 IPR025997 Periplasmic binding protein RG49_RS15455 19be1fe83a694bc8fcd9e001003ab5fe 296 SUPERFAMILY SSF53822 26 295 1.1E-88 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS15455 19be1fe83a694bc8fcd9e001003ab5fe 296 Gene3D G3DSA:3.40.50.2300 145 295 6.8E-55 T 10-03-2017 RG49_RS10860 5c5cbe2cf9268e395b232384268c3254 181 SUPERFAMILY SSF52980 4 178 2.47E-69 T 10-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 RG49_RS10860 5c5cbe2cf9268e395b232384268c3254 181 Pfam PF07152 YaeQ protein 1 173 6.0E-72 T 10-03-2017 IPR009822 YaeQ RG49_RS10860 5c5cbe2cf9268e395b232384268c3254 181 PIRSF PIRSF011484 1 180 9.7E-66 T 10-03-2017 IPR009822 YaeQ RG49_RS10860 5c5cbe2cf9268e395b232384268c3254 181 Gene3D G3DSA:3.10.640.10 1 179 1.1E-81 T 10-03-2017 RG49_RS10860 5c5cbe2cf9268e395b232384268c3254 181 SMART SM01322 1 176 5.5E-109 T 10-03-2017 IPR009822 YaeQ RG49_RS00005 1d64d6d0acec3177a77930c012108d81 265 SUPERFAMILY SSF55486 33 245 1.98E-39 T 10-03-2017 RG49_RS00005 1d64d6d0acec3177a77930c012108d81 265 Pfam PF06167 Glucose-regulated metallo-peptidase M90 16 243 1.2E-61 T 10-03-2017 IPR010384 MtfA family RG49_RS00005 1d64d6d0acec3177a77930c012108d81 265 Hamap MF_01593 Protein MtfA [mtfA]. 1 265 63.776 T 10-03-2017 IPR010384 MtfA family RG49_RS00005 1d64d6d0acec3177a77930c012108d81 265 Gene3D G3DSA:3.40.390.10 31 244 3.3E-25 T 10-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 43.873 T 10-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Gene3D G3DSA:3.30.1490.20 121 190 7.2E-34 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 SUPERFAMILY SSF51246 329 424 6.43E-34 T 10-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 2.3E-83 T 10-03-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 SMART SM01210 330 424 1.5E-57 T 10-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 425 2.3E-190 T 10-03-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 SUPERFAMILY SSF52440 1 103 1.29E-37 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Gene3D G3DSA:3.90.600.10 330 424 1.3E-36 T 10-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 10-03-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Gene3D G3DSA:3.30.470.20 191 328 2.1E-64 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Gene3D G3DSA:3.40.50.20 2 95 1.2E-38 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 2.2E-36 T 10-03-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 SUPERFAMILY SSF56059 104 323 6.54E-69 T 10-03-2017 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 332 422 3.1E-30 T 10-03-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 RG49_RS14055 9fb7f91c80c2a57277a226f2fc597147 429 SMART SM01209 103 296 1.9E-142 T 10-03-2017 RG49_RS08115 442f653a2d445547ad914a47ecff06fe 406 Gene3D G3DSA:3.40.50.620 14 235 4.7E-33 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS08115 442f653a2d445547ad914a47ecff06fe 406 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 30 234 3.7E-15 T 10-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 RG49_RS08115 442f653a2d445547ad914a47ecff06fe 406 Pfam PF11922 Domain of unknown function (DUF3440) 352 384 6.8E-8 T 10-03-2017 IPR021845 Protein of unknown function DUF3440 RG49_RS08115 442f653a2d445547ad914a47ecff06fe 406 Pfam PF11922 Domain of unknown function (DUF3440) 237 344 7.7E-27 T 10-03-2017 IPR021845 Protein of unknown function DUF3440 RG49_RS08115 442f653a2d445547ad914a47ecff06fe 406 SUPERFAMILY SSF52402 13 232 5.59E-41 T 10-03-2017 RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 10-03-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 Gene3D G3DSA:3.40.50.300 214 367 2.0E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 Pfam PF00271 Helicase conserved C-terminal domain 231 336 1.8E-26 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 5 457 72.209 T 10-03-2017 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 SMART SM00490 255 336 6.5E-28 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 Pfam PF03880 DbpA RNA binding domain 384 454 1.3E-20 T 10-03-2017 IPR005580 DbpA, RNA-binding domain RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 SUPERFAMILY SSF52540 72 350 5.0E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 SMART SM00487 22 219 6.9E-57 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 Pfam PF00270 DEAD/DEAH box helicase 27 191 1.2E-43 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS03805 446d2be54809106f2f61681f23e7b327 457 Gene3D G3DSA:3.40.50.300 2 209 9.9E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22635 2421f9ce637269efdde42df52115e903 513 SUPERFAMILY SSF53067 137 310 1.3E-47 T 10-03-2017 RG49_RS22635 2421f9ce637269efdde42df52115e903 513 SUPERFAMILY SSF109604 313 507 1.78E-58 T 10-03-2017 RG49_RS22635 2421f9ce637269efdde42df52115e903 513 PIRSF PIRSF001267 3 506 1.0E-204 T 10-03-2017 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 RG49_RS22635 2421f9ce637269efdde42df52115e903 513 Gene3D G3DSA:3.30.420.40 5 131 5.8E-41 T 10-03-2017 RG49_RS22635 2421f9ce637269efdde42df52115e903 513 Gene3D G3DSA:3.30.420.150 132 311 1.1E-52 T 10-03-2017 RG49_RS22635 2421f9ce637269efdde42df52115e903 513 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 13 306 3.9E-96 T 10-03-2017 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 RG49_RS22635 2421f9ce637269efdde42df52115e903 513 Pfam PF02541 Ppx/GppA phosphatase family 26 308 5.3E-105 T 10-03-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 RG49_RS22635 2421f9ce637269efdde42df52115e903 513 SUPERFAMILY SSF53067 13 133 1.3E-35 T 10-03-2017 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 10-03-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 SUPERFAMILY SSF54913 1 112 2.57E-46 T 10-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 PRINTS PR00340 P-II protein signature 2 17 5.2E-44 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 PRINTS PR00340 P-II protein signature 23 41 5.2E-44 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 PRINTS PR00340 P-II protein signature 83 103 5.2E-44 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 PRINTS PR00340 P-II protein signature 52 75 5.2E-44 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 10-03-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 6.0E-44 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 PIRSF PIRSF039144 1 112 3.8E-57 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 Gene3D G3DSA:3.30.70.120 1 112 8.1E-51 T 10-03-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal RG49_RS22300 d21bffb79c7b686addb2b8c85dee01ac 112 SMART SM00938 4 105 4.7E-66 T 10-03-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 RG49_RS09495 17a73fa6504185e959ec2bc37e59a4af 91 SUPERFAMILY SSF159871 2 90 2.62E-21 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS09495 17a73fa6504185e959ec2bc37e59a4af 91 Pfam PF07338 Protein of unknown function (DUF1471) 37 89 4.5E-13 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS09495 17a73fa6504185e959ec2bc37e59a4af 91 Gene3D G3DSA:3.30.1660.10 21 89 3.5E-22 T 10-03-2017 IPR025543 Dodecin-like RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 SUPERFAMILY SSF53901 277 400 7.85E-46 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 Gene3D G3DSA:3.40.47.10 283 400 6.4E-60 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 Gene3D G3DSA:3.40.47.10 152 199 6.4E-60 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 SUPERFAMILY SSF53901 4 276 1.12E-78 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 PIRSF PIRSF000429 1 401 1.0E-134 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 6.4E-46 T 10-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 10-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 Pfam PF00108 Thiolase, N-terminal domain 5 269 3.0E-74 T 10-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 10-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 10-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 2 401 4.4E-225 T 10-03-2017 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 Gene3D G3DSA:3.40.47.10 4 125 4.4E-67 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 Gene3D G3DSA:3.40.47.10 200 282 4.4E-67 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS03410 023dd58ebc302d8263c2c576ec3597a9 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 399 2.3E-138 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS16540 c6bbdd11c9814da6cc8cda356794a3d8 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 4.8E-12 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS16540 c6bbdd11c9814da6cc8cda356794a3d8 324 Pfam PF03466 LysR substrate binding domain 95 303 3.9E-17 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS16540 c6bbdd11c9814da6cc8cda356794a3d8 324 SUPERFAMILY SSF46785 5 115 4.79E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16540 c6bbdd11c9814da6cc8cda356794a3d8 324 Gene3D G3DSA:3.40.190.10 187 271 1.4E-5 T 10-03-2017 RG49_RS16540 c6bbdd11c9814da6cc8cda356794a3d8 324 SUPERFAMILY SSF53850 94 307 4.71E-22 T 10-03-2017 RG49_RS16540 c6bbdd11c9814da6cc8cda356794a3d8 324 Gene3D G3DSA:3.40.190.10 146 186 3.1E-7 T 10-03-2017 RG49_RS16540 c6bbdd11c9814da6cc8cda356794a3d8 324 Gene3D G3DSA:1.10.10.10 7 91 7.0E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09820 4645348bad64594d4dc3d4d5f49f2be2 158 Pfam PF00959 Phage lysozyme 33 140 3.2E-23 T 10-03-2017 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 RG49_RS09820 4645348bad64594d4dc3d4d5f49f2be2 158 Gene3D G3DSA:1.10.530.10 2 156 3.1E-68 T 10-03-2017 RG49_RS09820 4645348bad64594d4dc3d4d5f49f2be2 158 SUPERFAMILY SSF53955 2 152 1.41E-54 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS19035 a9f67a7b71d1debd4fa3d6551bd8d009 444 Gene3D G3DSA:1.20.1250.20 243 441 5.3E-35 T 10-03-2017 RG49_RS19035 a9f67a7b71d1debd4fa3d6551bd8d009 444 Gene3D G3DSA:1.20.1250.20 15 214 2.8E-45 T 10-03-2017 RG49_RS19035 a9f67a7b71d1debd4fa3d6551bd8d009 444 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 25 434 1.7E-137 T 10-03-2017 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS19035 a9f67a7b71d1debd4fa3d6551bd8d009 444 PIRSF PIRSF002808 3 444 3.5E-36 T 10-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS19035 a9f67a7b71d1debd4fa3d6551bd8d009 444 Pfam PF07690 Major Facilitator Superfamily 23 365 3.5E-47 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS19035 a9f67a7b71d1debd4fa3d6551bd8d009 444 SUPERFAMILY SSF103473 6 443 1.24E-78 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 SUPERFAMILY SSF52343 100 231 2.88E-36 T 10-03-2017 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 Pfam PF00970 Oxidoreductase FAD-binding domain 6 95 5.3E-7 T 10-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 Pfam PF00175 Oxidoreductase NAD-binding domain 108 211 5.5E-23 T 10-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 31 43 1.1E-13 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 107 126 1.1E-13 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 47 54 1.1E-13 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 91 100 1.1E-13 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 141 1.1E-13 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 Gene3D G3DSA:2.40.30.10 3 98 1.9E-30 T 10-03-2017 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 SUPERFAMILY SSF63380 3 97 4.12E-23 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS14975 b6cb369f06acaecc00322377c74e9f11 233 Gene3D G3DSA:3.40.50.80 100 231 4.2E-39 T 10-03-2017 RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 Hamap MF_01819 Transcriptional regulator SlyA [slyA]. 1 143 46.12 T 10-03-2017 IPR023071 Transcriptional regulator, SlyA RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 Pfam PF01047 MarR family 29 87 1.3E-18 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 SMART SM00347 22 123 4.0E-32 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 1.3E-28 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.3E-28 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.3E-28 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.3E-28 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 Gene3D G3DSA:1.10.10.10 3 137 3.0E-37 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 SUPERFAMILY SSF46785 4 139 1.43E-34 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS01835 e5515a1baee1dd14ef6d2b4f35b2c1b0 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 10-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site RG49_RS00560 3677727fb049381a16204e8dbbc3db5e 323 Gene3D G3DSA:3.40.50.150 91 312 2.6E-28 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00560 3677727fb049381a16204e8dbbc3db5e 323 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 12 322 54.931 T 10-03-2017 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 RG49_RS00560 3677727fb049381a16204e8dbbc3db5e 323 SUPERFAMILY SSF53335 91 323 1.04E-33 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00560 3677727fb049381a16204e8dbbc3db5e 323 Pfam PF08003 Protein of unknown function (DUF1698) 7 322 8.2E-173 T 10-03-2017 IPR027555 tRNA (mo5U34)-methyltransferase-like RG49_RS00560 3677727fb049381a16204e8dbbc3db5e 323 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 8 321 4.7E-148 T 10-03-2017 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 RG49_RS15795 2268f4daf4bf7885738375c940773157 142 Pfam PF00011 Hsp20/alpha crystallin family 39 135 4.9E-21 T 10-03-2017 IPR002068 Alpha crystallin/Hsp20 domain RG49_RS15795 2268f4daf4bf7885738375c940773157 142 SUPERFAMILY SSF49764 30 134 4.19E-18 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS15795 2268f4daf4bf7885738375c940773157 142 Gene3D G3DSA:2.60.40.790 9 134 3.3E-15 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS15795 2268f4daf4bf7885738375c940773157 142 Hamap MF_02001 Small heat shock protein IbpB [ibpB]. 1 142 47.247 T 10-03-2017 IPR022848 Small heat shock protein IbpB RG49_RS17985 4debf81d3296fd0f9a89452fce84c603 489 Gene3D G3DSA:1.10.101.10 399 464 6.9E-8 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS17985 4debf81d3296fd0f9a89452fce84c603 489 SUPERFAMILY SSF52540 5 221 5.71E-10 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17985 4debf81d3296fd0f9a89452fce84c603 489 SUPERFAMILY SSF47090 400 470 7.53E-12 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS17985 4debf81d3296fd0f9a89452fce84c603 489 Gene3D G3DSA:3.40.50.300 5 137 2.2E-6 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17985 4debf81d3296fd0f9a89452fce84c603 489 Pfam PF13401 AAA domain 20 137 4.0E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17985 4debf81d3296fd0f9a89452fce84c603 489 Pfam PF01471 Putative peptidoglycan binding domain 408 461 1.8E-8 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS17985 4debf81d3296fd0f9a89452fce84c603 489 Gene3D G3DSA:3.90.70.10 309 393 2.6E-4 T 10-03-2017 RG49_RS23975 3b81874aa28696a2565d843cf8ac145e 1534 SMART SM01360 871 962 8.3E-20 T 10-03-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 RG49_RS23975 3b81874aa28696a2565d843cf8ac145e 1534 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 660 806 6.5E-12 T 10-03-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 RG49_RS23975 3b81874aa28696a2565d843cf8ac145e 1534 SUPERFAMILY SSF48239 1057 1150 1.88E-5 T 10-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid RG49_RS23975 3b81874aa28696a2565d843cf8ac145e 1534 Pfam PF01835 MG2 domain 344 440 2.3E-17 T 10-03-2017 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 RG49_RS23975 3b81874aa28696a2565d843cf8ac145e 1534 SMART SM01359 660 806 7.8E-29 T 10-03-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 RG49_RS23975 3b81874aa28696a2565d843cf8ac145e 1534 Pfam PF00207 Alpha-2-macroglobulin family 871 954 3.0E-15 T 10-03-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 6 418 5.7E-147 T 10-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 265 284 4.6E-20 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 376 389 4.6E-20 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 51 69 4.6E-20 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 71 83 4.6E-20 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 182 195 4.6E-20 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 14 419 40.081 T 10-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 216 229 - T 10-03-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 51 69 - T 10-03-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 32 276 6.1E-69 T 10-03-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 386 408 8.6E-28 T 10-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 69 86 8.6E-28 T 10-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 157 166 8.6E-28 T 10-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 293 311 8.6E-28 T 10-03-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 SUPERFAMILY SSF51419 32 278 7.85E-59 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 280 395 7.4E-17 T 10-03-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 Gene3D G3DSA:3.20.20.10 36 262 3.4E-66 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 Gene3D G3DSA:2.40.37.10 263 419 6.5E-59 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS20835 ca1063d432cd5ee537a415830b61244f 420 SUPERFAMILY SSF50621 250 419 1.42E-59 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 SMART SM00490 492 589 5.3E-10 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 Gene3D G3DSA:3.40.50.300 456 632 1.3E-28 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 Gene3D G3DSA:3.40.50.300 198 380 7.8E-39 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 SMART SM00487 195 391 3.2E-20 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 SUPERFAMILY SSF52540 214 440 1.76E-41 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 SUPERFAMILY SSF52540 503 601 1.76E-41 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 Hamap MF_00983 Probable primosomal protein N' [priA]. 6 732 26.273 T 10-03-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 Pfam PF00270 DEAD/DEAH box helicase 203 362 6.2E-16 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 TIGRFAM TIGR00595 priA: primosomal protein N' 221 730 4.9E-220 T 10-03-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 RG49_RS14450 048923b337e7c3413696e4a43a4e9892 732 Pfam PF00271 Helicase conserved C-terminal domain 521 589 1.4E-5 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 283 2.1E-95 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 PIRSF PIRSF001359 1 284 1.0E-114 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 TIGRFAM TIGR01858 tag_bisphos_ald: class II aldolase, tagatose bisphosphate family 3 284 9.4E-164 T 10-03-2017 IPR011288 D-tagatose-bisphosphate aldolase, class II, subunit KbaY/GatY GO:0005975|GO:0008270|GO:0009025 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 4.5E-111 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 Hamap MF_01293 D-tagatose-1,6-bisphosphate aldolase subunit KbaY [kbaY]. 1 286 77.607 T 10-03-2017 IPR023788 D-tagatose-bisphosphate aldolase, class II, subunit KbaY GO:0005975|GO:0008270|GO:0009025|GO:2001059 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 SUPERFAMILY SSF51569 3 283 1.61E-96 T 10-03-2017 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 Gene3D G3DSA:3.20.20.70 1 284 1.7E-107 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS18970 a514fa9e4b4a12f2acbee366f3c2ef85 286 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 71 84 - T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 Gene3D G3DSA:3.90.1150.10 421 593 5.7E-71 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 350 364 - T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 Gene3D G3DSA:3.90.100.10 594 719 2.4E-39 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 TIGRFAM TIGR04301 ODC_inducible: ornithine decarboxylase SpeF 1 718 0.0 T 10-03-2017 IPR027568 Ornithine decarboxylase SpeF GO:0004586 KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 4 103 1.5E-22 T 10-03-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 109 551 1.0E-200 T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 Gene3D G3DSA:3.40.640.10 109 418 6.6E-114 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 SUPERFAMILY SSF53383 109 566 5.43E-120 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 Gene3D G3DSA:3.40.50.220 1 107 1.7E-36 T 10-03-2017 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 SUPERFAMILY SSF52172 1 107 4.52E-33 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 PIRSF PIRSF009393 1 719 1.4E-291 T 10-03-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 576 705 1.5E-48 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS07635 733142417d0007f86b58ea4b68783f95 732 SUPERFAMILY SSF55904 571 718 1.7E-47 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 263 276 7.6E-19 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 566 579 7.6E-19 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 124 142 7.6E-19 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 146 158 7.6E-19 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 357 376 7.6E-19 T 10-03-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 SUPERFAMILY SSF51419 92 369 1.48E-67 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 124 142 - T 10-03-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 Gene3D G3DSA:3.20.20.10 94 355 6.7E-61 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 TIGRFAM TIGR01273 speA: arginine decarboxylase 31 656 1.6E-280 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 28 657 43.765 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 99 368 8.0E-74 T 10-03-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PIRSF PIRSF001336 17 658 2.8E-257 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 SUPERFAMILY SSF50621 482 584 4.88E-7 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 391 585 3.4E-23 T 10-03-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 Gene3D G3DSA:2.40.37.10 356 380 4.6E-12 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 Gene3D G3DSA:2.40.37.10 479 611 4.6E-12 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 301 314 - T 10-03-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 488 509 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 347 364 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 196 217 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 170 185 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 220 242 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 116 130 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 566 587 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 513 538 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS20200 202dc8fc4a86aba6613135dd9fb94db3 658 PRINTS PR01180 Arginine decarboxylase signature 92 107 1.7E-74 T 10-03-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 32 48 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 123 139 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 293 319 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 3.1E-97 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 Pfam PF13343 Bacterial extracellular solute-binding protein 77 322 6.5E-39 T 10-03-2017 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 PIRSF PIRSF019574 1 348 3.5E-135 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 Gene3D G3DSA:3.40.190.10 270 313 3.7E-65 T 10-03-2017 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 Gene3D G3DSA:3.40.190.10 26 132 3.7E-65 T 10-03-2017 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 Gene3D G3DSA:3.40.190.10 134 269 7.4E-26 T 10-03-2017 RG49_RS04995 c3f307642155ebe32b4c91383e8cadac 348 SUPERFAMILY SSF53850 27 345 6.34E-98 T 10-03-2017 RG49_RS10045 573dd6acd07ddce9af129dbfb8766613 571 SUPERFAMILY SSF51735 407 547 2.41E-23 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS10045 573dd6acd07ddce9af129dbfb8766613 571 Gene3D G3DSA:3.40.50.720 408 545 2.2E-28 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS10045 573dd6acd07ddce9af129dbfb8766613 571 Pfam PF00999 Sodium/hydrogen exchanger family 9 372 1.0E-58 T 10-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 RG49_RS10045 573dd6acd07ddce9af129dbfb8766613 571 Pfam PF02254 TrkA-N domain 411 517 5.2E-17 T 10-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 RG49_RS12175 1094c1b821c73868309d18020f59f3ea 423 PIRSF PIRSF006066 1 423 2.7E-124 T 10-03-2017 IPR004681 TRAP transporter permease protein GO:0016021 RG49_RS12175 1094c1b821c73868309d18020f59f3ea 423 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 418 1.2E-106 T 10-03-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit RG49_RS12175 1094c1b821c73868309d18020f59f3ea 423 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 23 422 1.7E-119 T 10-03-2017 IPR004681 TRAP transporter permease protein GO:0016021 RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 PIRSF PIRSF000156 1 887 0.0 T 10-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 Gene3D G3DSA:3.40.50.970 473 705 1.5E-120 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 Gene3D G3DSA:3.40.50.920 707 885 3.5E-77 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 SUPERFAMILY SSF52518 474 701 7.53E-99 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 106 296 1.2E-9 T 10-03-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 SUPERFAMILY SSF52518 58 469 4.42E-145 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 Gene3D G3DSA:3.40.50.970 59 469 1.4E-158 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 SUPERFAMILY SSF52922 702 885 1.12E-64 T 10-03-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 RG49_RS11285 6661e42b76599483a127a1fe3c7d0752 887 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 5 886 0.0 T 10-03-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 RG49_RS24490 df154592957e94df974b7a98822403d6 478 Gene3D G3DSA:2.20.200.10 104 153 8.6E-16 T 10-03-2017 RG49_RS24490 df154592957e94df974b7a98822403d6 478 Gene3D G3DSA:2.20.200.10 325 360 8.6E-16 T 10-03-2017 RG49_RS24490 df154592957e94df974b7a98822403d6 478 SUPERFAMILY SSF56954 7 476 5.36E-75 T 10-03-2017 RG49_RS24490 df154592957e94df974b7a98822403d6 478 Pfam PF02321 Outer membrane efflux protein 293 473 9.0E-13 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS24490 df154592957e94df974b7a98822403d6 478 Pfam PF02321 Outer membrane efflux protein 69 266 1.9E-18 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS24490 df154592957e94df974b7a98822403d6 478 Gene3D G3DSA:1.20.1600.10 53 93 7.7E-66 T 10-03-2017 RG49_RS24490 df154592957e94df974b7a98822403d6 478 Gene3D G3DSA:1.20.1600.10 362 475 7.7E-66 T 10-03-2017 RG49_RS24490 df154592957e94df974b7a98822403d6 478 Gene3D G3DSA:1.20.1600.10 154 324 7.7E-66 T 10-03-2017 RG49_RS24490 df154592957e94df974b7a98822403d6 478 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 16 475 6.4E-82 T 10-03-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 RG49_RS08395 dbc076cf1eb0043fd3e642b5bd577eca 253 Gene3D G3DSA:1.10.10.60 197 246 7.1E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08395 dbc076cf1eb0043fd3e642b5bd577eca 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 244 1.2E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS08395 dbc076cf1eb0043fd3e642b5bd577eca 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 213 228 1.2E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS08395 dbc076cf1eb0043fd3e642b5bd577eca 253 Pfam PF12833 Helix-turn-helix domain 169 245 5.5E-15 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS08395 dbc076cf1eb0043fd3e642b5bd577eca 253 SUPERFAMILY SSF46689 197 248 1.46E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08395 dbc076cf1eb0043fd3e642b5bd577eca 253 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 198 240 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS08395 dbc076cf1eb0043fd3e642b5bd577eca 253 SMART SM00342 162 244 4.2E-28 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS22040 56a38ea72f0be578bfef7f17b93bd275 113 Gene3D G3DSA:3.30.160.100 3 91 1.2E-32 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS22040 56a38ea72f0be578bfef7f17b93bd275 113 SUPERFAMILY SSF69754 3 111 8.37E-34 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS22040 56a38ea72f0be578bfef7f17b93bd275 113 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 97 7.1E-36 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS22040 56a38ea72f0be578bfef7f17b93bd275 113 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 91 7.2E-22 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS01475 cdfea428da3ddfef589eeea2d2d511a1 249 Hamap MF_01005 Vitamin B12 import ATP-binding protein BtuD [btuD]. 4 248 46.231 T 10-03-2017 IPR023693 ABC transporter, vitamin B12, BtuD GO:0005524|GO:0015889|GO:0016887 RG49_RS01475 cdfea428da3ddfef589eeea2d2d511a1 249 Pfam PF00005 ABC transporter 18 162 2.0E-21 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS01475 cdfea428da3ddfef589eeea2d2d511a1 249 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS01475 cdfea428da3ddfef589eeea2d2d511a1 249 Gene3D G3DSA:3.40.50.300 16 231 1.9E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01475 cdfea428da3ddfef589eeea2d2d511a1 249 SUPERFAMILY SSF52540 14 226 4.3E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01475 cdfea428da3ddfef589eeea2d2d511a1 249 SMART SM00382 25 224 5.1E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS01285 cf041ac51fd87adcd5c8f2a87e24742f 191 Hamap MF_01591 Protein Ves [ves]. 1 191 59.555 T 10-03-2017 IPR023482 Uncharacterised protein family Ves RG49_RS01285 cf041ac51fd87adcd5c8f2a87e24742f 191 Pfam PF05962 HutD 5 175 4.4E-44 T 10-03-2017 IPR010282 Uncharacterised protein family HutD/Ves RG49_RS01285 cf041ac51fd87adcd5c8f2a87e24742f 191 SUPERFAMILY SSF51182 1 182 8.63E-46 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS01285 cf041ac51fd87adcd5c8f2a87e24742f 191 Gene3D G3DSA:2.60.120.10 8 112 1.1E-34 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 Pfam PF07730 Histidine kinase 390 453 7.0E-19 T 10-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 Gene3D G3DSA:3.30.565.10 447 583 5.5E-13 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 496 583 1.9E-11 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 Pfam PF00672 HAMP domain 160 224 8.1E-11 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 SMART SM00304 176 228 1.4E-10 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 SUPERFAMILY SSF158472 178 225 2.09E-5 T 10-03-2017 RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 SMART SM00387 494 587 5.0E-15 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 PIRSF PIRSF003167 1 597 1.7E-196 T 10-03-2017 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 SUPERFAMILY SSF55874 467 583 1.7E-19 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS04510 6750e1d1e39cbbc861c1a454e853fa12 598 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 35 130 1.6E-9 T 10-03-2017 IPR029095 NarX-like, N-terminal RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 ProSitePatterns PS00460 Glutathione peroxidases active site. 25 40 - T 10-03-2017 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 SUPERFAMILY SSF52833 6 182 3.94E-53 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 Gene3D G3DSA:3.40.30.10 5 182 4.7E-63 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 Pfam PF00255 Glutathione peroxidase 7 111 5.2E-46 T 10-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 PIRSF PIRSF000303 1 183 2.3E-64 T 10-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 Hamap MF_02061 Thioredoxin/glutathione peroxidase BtuE [btuE]. 3 183 51.318 T 10-03-2017 IPR033674 Thioredoxin/glutathione peroxidase BtuE RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 61 68 - T 10-03-2017 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 PRINTS PR01011 Glutathione peroxidase family signature 23 40 3.8E-19 T 10-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 PRINTS PR01011 Glutathione peroxidase family signature 58 74 3.8E-19 T 10-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 RG49_RS01470 41f8e0c961670fdf341351b3b1031efe 183 PRINTS PR01011 Glutathione peroxidase family signature 143 152 3.8E-19 T 10-03-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 RG49_RS11755 fb4da09f65b6c5940f6e07713a8e2d6f 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 87 1.2E-34 T 10-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS11755 fb4da09f65b6c5940f6e07713a8e2d6f 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 3.0E-36 T 10-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS11755 fb4da09f65b6c5940f6e07713a8e2d6f 87 Gene3D G3DSA:1.20.58.110 3 87 2.4E-32 T 10-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS11755 fb4da09f65b6c5940f6e07713a8e2d6f 87 Pfam PF01649 Ribosomal protein S20 2 84 2.4E-28 T 10-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS11755 fb4da09f65b6c5940f6e07713a8e2d6f 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.208 T 10-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS11755 fb4da09f65b6c5940f6e07713a8e2d6f 87 SUPERFAMILY SSF46992 3 86 1.57E-31 T 10-03-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS10155 0a6310b4ec77ab82a712f774298c9290 253 Pfam PF02498 BRO family, N-terminal domain 19 117 1.6E-8 T 10-03-2017 IPR003497 BRO N-terminal domain RG49_RS10155 0a6310b4ec77ab82a712f774298c9290 253 SMART SM01040 18 117 6.2E-7 T 10-03-2017 IPR003497 BRO N-terminal domain RG49_RS13450 bcf85d0273e13ba7f88498993ab71566 262 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 4 250 4.2E-105 T 10-03-2017 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 RG49_RS13450 bcf85d0273e13ba7f88498993ab71566 262 SUPERFAMILY SSF52540 3 240 2.54E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13450 bcf85d0273e13ba7f88498993ab71566 262 Gene3D G3DSA:3.40.50.300 3 243 2.0E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13450 bcf85d0273e13ba7f88498993ab71566 262 SMART SM00382 29 229 7.8E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS13450 bcf85d0273e13ba7f88498993ab71566 262 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS13450 bcf85d0273e13ba7f88498993ab71566 262 Pfam PF00005 ABC transporter 20 181 5.2E-35 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 10-03-2017 IPR018201 Beta-ketoacyl synthase, active site RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 SMART SM00825 Beta-ketoacyl synthase 6 413 9.7E-14 T 10-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 SUPERFAMILY SSF53901 215 412 1.54E-73 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 SUPERFAMILY SSF53901 3 252 7.02E-78 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 Gene3D G3DSA:3.40.47.10 2 260 1.1E-76 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 411 1.6E-196 T 10-03-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 6.5E-63 T 10-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 Gene3D G3DSA:3.40.47.10 263 412 1.1E-63 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 1.6E-39 T 10-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal RG49_RS05170 401689333e60d09779c2ba651ccf31a1 413 PIRSF PIRSF000447 1 413 5.2E-206 T 10-03-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 RG49_RS10060 13e63415a7f9e35911ec48c6039deedd 211 Pfam PF00239 Resolvase, N terminal domain 3 159 2.4E-35 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS10060 13e63415a7f9e35911ec48c6039deedd 211 SUPERFAMILY SSF53041 1 159 1.96E-31 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS10060 13e63415a7f9e35911ec48c6039deedd 211 Gene3D G3DSA:1.10.10.10 178 204 3.8E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS10060 13e63415a7f9e35911ec48c6039deedd 211 ProSitePatterns PS00398 Site-specific recombinases signature 2. 62 74 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS10060 13e63415a7f9e35911ec48c6039deedd 211 Gene3D G3DSA:3.40.50.1390 3 141 1.8E-29 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS10060 13e63415a7f9e35911ec48c6039deedd 211 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS10060 13e63415a7f9e35911ec48c6039deedd 211 SMART SM00857 3 159 1.3E-39 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 SUPERFAMILY SSF46689 1 68 3.64E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 Gene3D G3DSA:1.10.10.60 1 44 7.8E-22 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 SUPERFAMILY SSF48498 84 200 6.43E-14 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-12 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-12 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 202 8.6E-52 T 10-03-2017 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.2E-19 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 Gene3D G3DSA:1.10.10.60 45 62 7.9E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 10-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site RG49_RS08785 27e8f13d77a01af2c9129bf6c6703e9a 215 Gene3D G3DSA:1.10.357.10 63 203 1.8E-18 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS04855 336a645316151a3aaa33bec5540dba53 507 SMART SM00052 245 491 1.0E-115 T 10-03-2017 IPR001633 EAL domain RG49_RS04855 336a645316151a3aaa33bec5540dba53 507 Gene3D G3DSA:3.20.20.450 251 496 2.6E-77 T 10-03-2017 IPR001633 EAL domain RG49_RS04855 336a645316151a3aaa33bec5540dba53 507 Pfam PF00563 EAL domain 251 486 8.3E-65 T 10-03-2017 IPR001633 EAL domain RG49_RS04855 336a645316151a3aaa33bec5540dba53 507 Pfam PF12792 CSS motif domain associated with EAL 33 217 3.8E-26 T 10-03-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain RG49_RS04855 336a645316151a3aaa33bec5540dba53 507 SUPERFAMILY SSF141868 251 499 1.57E-76 T 10-03-2017 IPR001633 EAL domain RG49_RS05365 f8d868a51a76ba3ac3148a3ac2d976a3 188 SUPERFAMILY SSF81342 5 181 3.53E-40 T 10-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 RG49_RS05365 f8d868a51a76ba3ac3148a3ac2d976a3 188 Pfam PF01292 Prokaryotic cytochrome b561 9 180 1.8E-28 T 10-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 RG49_RS05365 f8d868a51a76ba3ac3148a3ac2d976a3 188 Gene3D G3DSA:1.20.950.20 87 174 2.4E-5 T 10-03-2017 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 SMART SM00091 98 165 1.3E-5 T 10-03-2017 IPR000014 PAS domain RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 424 3.1E-24 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 Pfam PF11808 Domain of unknown function (DUF3329) 6 91 4.4E-28 T 10-03-2017 IPR021766 Protein of unknown function DUF3329 GO:0004673 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 SMART SM00388 203 269 7.3E-23 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 SUPERFAMILY SSF55874 259 423 3.14E-43 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 SUPERFAMILY SSF47384 190 268 1.77E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 7.3E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 7.3E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 7.3E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 422 7.3E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 95 421 4.2E-138 T 10-03-2017 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 Gene3D G3DSA:3.30.450.20 99 194 6.2E-10 T 10-03-2017 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 268 2.1E-18 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 Gene3D G3DSA:3.30.565.10 255 422 4.6E-44 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 SMART SM00387 313 425 7.5E-38 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 Pfam PF00989 PAS fold 99 194 1.1E-10 T 10-03-2017 IPR013767 PAS fold GO:0006355 RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 SUPERFAMILY SSF55785 87 195 1.54E-10 T 10-03-2017 IPR000014 PAS domain RG49_RS09130 731a1fe484ec55c077af0e91244c1ad6 431 Gene3D G3DSA:1.10.287.130 195 254 1.8E-22 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS23970 241a0895d7c02ebc1fc4df3418db684b 207 Pfam PF06672 Protein of unknown function (DUF1175) 20 205 5.8E-76 T 10-03-2017 IPR009558 Protein of unknown function DUF1175 RG49_RS23970 241a0895d7c02ebc1fc4df3418db684b 207 Gene3D G3DSA:3.90.1720.10 52 177 1.8E-6 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS22905 12095a26f4d9257993b59f844e6ee2e6 395 Gene3D G3DSA:1.20.1090.10 203 394 2.5E-64 T 10-03-2017 RG49_RS22905 12095a26f4d9257993b59f844e6ee2e6 395 SUPERFAMILY SSF56796 22 393 9.16E-114 T 10-03-2017 RG49_RS22905 12095a26f4d9257993b59f844e6ee2e6 395 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 278 298 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS22905 12095a26f4d9257993b59f844e6ee2e6 395 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 191 219 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS22905 12095a26f4d9257993b59f844e6ee2e6 395 Pfam PF00465 Iron-containing alcohol dehydrogenase 27 387 2.9E-112 T 10-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 RG49_RS22905 12095a26f4d9257993b59f844e6ee2e6 395 Gene3D G3DSA:3.40.50.1970 22 202 1.5E-52 T 10-03-2017 RG49_RS07680 0791e3a65ee6629fa7d1b8450305c4f7 176 PIRSF PIRSF038996 1 172 2.2E-71 T 10-03-2017 IPR010086 Flavodoxin, long chain GO:0010181 RG49_RS07680 0791e3a65ee6629fa7d1b8450305c4f7 176 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 10-03-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 RG49_RS07680 0791e3a65ee6629fa7d1b8450305c4f7 176 Pfam PF00258 Flavodoxin 6 160 2.8E-34 T 10-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 RG49_RS07680 0791e3a65ee6629fa7d1b8450305c4f7 176 Gene3D G3DSA:3.40.50.360 3 168 1.0E-63 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS07680 0791e3a65ee6629fa7d1b8450305c4f7 176 SUPERFAMILY SSF52218 5 170 1.96E-54 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS07680 0791e3a65ee6629fa7d1b8450305c4f7 176 TIGRFAM TIGR01752 flav_long: flavodoxin 4 168 2.6E-78 T 10-03-2017 IPR010086 Flavodoxin, long chain GO:0010181 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 87 7.2E-22 T 10-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 SUPERFAMILY SSF47323 454 577 3.34E-35 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 SUPERFAMILY SSF52374 110 454 5.0E-99 T 10-03-2017 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 Gene3D G3DSA:3.40.50.620 111 453 2.3E-119 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 SMART SM01016 5 87 7.8E-29 T 10-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 577 1.4E-219 T 10-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 Gene3D G3DSA:3.30.1360.70 2 105 3.6E-35 T 10-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 Pfam PF00750 tRNA synthetases class I (R) 95 446 1.1E-179 T 10-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 SUPERFAMILY SSF55190 2 100 1.83E-23 T 10-03-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 Gene3D G3DSA:1.10.730.10 454 577 5.2E-36 T 10-03-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 577 29.648 T 10-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 9.0E-26 T 10-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 9.0E-26 T 10-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 9.0E-26 T 10-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 9.0E-26 T 10-03-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 Pfam PF05746 DALR anticodon binding domain 460 577 2.6E-35 T 10-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 RG49_RS00530 5178eaa386ae88dab8a31b3a0a4debed 577 SMART SM00836 460 577 1.4E-36 T 10-03-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 Gene3D G3DSA:3.90.190.20 343 484 2.3E-59 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 SUPERFAMILY SSF53623 105 338 7.85E-80 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 491 1.2E-165 T 10-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 SUPERFAMILY SSF53244 339 491 7.78E-52 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 SUPERFAMILY SSF63418 5 103 1.7E-22 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 425 1.5E-25 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 Gene3D G3DSA:3.40.1390.10 4 103 9.1E-34 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 4 491 35.031 T 10-03-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 Pfam PF08245 Mur ligase middle domain 114 318 8.4E-52 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 Gene3D G3DSA:3.40.1190.10 105 342 8.0E-83 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11430 a7130ae9c63a8db010032be1082cb87a 495 Pfam PF01225 Mur ligase family, catalytic domain 25 102 7.1E-12 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 SUPERFAMILY SSF53335 76 431 4.15E-94 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 Gene3D G3DSA:2.40.50.140 2 87 2.1E-32 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 SUPERFAMILY SSF50249 2 67 1.48E-14 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 Pfam PF01938 TRAM domain 11 67 4.5E-13 T 10-03-2017 IPR002792 TRAM domain RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 18 432 67.333 T 10-03-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 414 424 - T 10-03-2017 IPR030391 RNA methyltransferase TrmA, conserved site RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 363 393 - T 10-03-2017 IPR030390 RNA methyltransferase TrmA, active site RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 24 424 2.2E-171 T 10-03-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 117 431 4.1E-28 T 10-03-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 RG49_RS21125 da00c6751b87c864ac9c995d1fbbc0ba 433 Gene3D G3DSA:3.40.50.150 250 431 5.8E-64 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS22850 fe506aea138ef6a4ad7fb74ea420b651 316 Pfam PF00923 Transaldolase 13 310 1.0E-101 T 10-03-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS22850 fe506aea138ef6a4ad7fb74ea420b651 316 SUPERFAMILY SSF51569 1 315 1.88E-114 T 10-03-2017 RG49_RS22850 fe506aea138ef6a4ad7fb74ea420b651 316 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS22850 fe506aea138ef6a4ad7fb74ea420b651 316 ProSitePatterns PS00958 Transaldolase active site. 128 145 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS22850 fe506aea138ef6a4ad7fb74ea420b651 316 Gene3D G3DSA:3.20.20.70 1 315 2.0E-133 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS22850 fe506aea138ef6a4ad7fb74ea420b651 316 TIGRFAM TIGR00874 talAB: transaldolase 2 316 9.5E-166 T 10-03-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS22850 fe506aea138ef6a4ad7fb74ea420b651 316 Hamap MF_00492 Transaldolase [tal]. 1 316 53.135 T 10-03-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS01825 fd8919f6b2d6a3ae776d12d149eb4130 285 Gene3D G3DSA:2.40.50.100 151 184 1.6E-19 T 10-03-2017 RG49_RS01825 fd8919f6b2d6a3ae776d12d149eb4130 285 Gene3D G3DSA:2.40.50.100 43 77 1.6E-19 T 10-03-2017 RG49_RS01825 fd8919f6b2d6a3ae776d12d149eb4130 285 Pfam PF00529 HlyD membrane-fusion protein of T1SS 17 276 7.1E-9 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS01825 fd8919f6b2d6a3ae776d12d149eb4130 285 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 230 4.0E-18 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS01825 fd8919f6b2d6a3ae776d12d149eb4130 285 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 230 8.1E-40 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS01825 fd8919f6b2d6a3ae776d12d149eb4130 285 SUPERFAMILY SSF111369 43 218 8.76E-26 T 10-03-2017 RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SMART SM00052 540 786 1.8E-125 T 10-03-2017 IPR001633 EAL domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SUPERFAMILY SSF55785 25 134 1.64E-19 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SMART SM00091 12 78 4.4E-9 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SMART SM00091 136 203 3.0E-7 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SUPERFAMILY SSF55785 143 250 9.6E-17 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Pfam PF13426 PAS domain 149 250 6.8E-11 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Pfam PF13426 PAS domain 24 125 1.5E-12 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SMART SM00086 209 251 1.1E-5 T 10-03-2017 IPR001610 PAC motif RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SMART SM00086 88 128 0.0094 T 10-03-2017 IPR001610 PAC motif RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 126 9.4E-22 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 256 1.1E-14 T 10-03-2017 IPR000014 PAS domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SUPERFAMILY SSF55073 381 532 4.08E-28 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SMART SM00267 365 530 2.6E-48 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 SUPERFAMILY SSF141868 547 794 9.29E-83 T 10-03-2017 IPR001633 EAL domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Gene3D G3DSA:3.30.450.20 18 124 6.2E-23 T 10-03-2017 RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Gene3D G3DSA:3.30.70.270 378 538 2.1E-30 T 10-03-2017 RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Pfam PF00990 Diguanylate cyclase, GGDEF domain 377 525 8.6E-22 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Pfam PF00563 EAL domain 547 781 6.8E-68 T 10-03-2017 IPR001633 EAL domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 526 8.7E-15 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Gene3D G3DSA:3.20.20.450 545 793 9.0E-91 T 10-03-2017 IPR001633 EAL domain RG49_RS02885 2f590e20b0671568b11a3fa93077b79c 799 Gene3D G3DSA:3.30.450.20 128 249 2.3E-17 T 10-03-2017 RG49_RS09520 8e6d41c61a016da310468948f231438f 460 Gene3D G3DSA:2.30.40.10 75 126 7.3E-7 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS09520 8e6d41c61a016da310468948f231438f 460 Gene3D G3DSA:3.20.20.140 127 405 8.5E-93 T 10-03-2017 RG49_RS09520 8e6d41c61a016da310468948f231438f 460 SUPERFAMILY SSF51556 118 411 1.36E-72 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS09520 8e6d41c61a016da310468948f231438f 460 Pfam PF07969 Amidohydrolase family 167 431 1.6E-10 T 10-03-2017 IPR013108 Amidohydrolase 3 RG49_RS09520 8e6d41c61a016da310468948f231438f 460 SUPERFAMILY SSF51338 75 132 1.59E-5 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 Gene3D G3DSA:3.30.750.70 72 153 3.2E-17 T 10-03-2017 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 SUPERFAMILY SSF100950 73 233 9.21E-31 T 10-03-2017 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 SUPERFAMILY SSF46785 3 76 1.43E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 9.8E-14 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 9.8E-14 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 Gene3D G3DSA:1.10.10.10 1 58 3.1E-12 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 7.8E-26 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 SMART SM00420 6 58 1.0E-28 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 SMART SM01134 72 233 5.1E-74 T 10-03-2017 RG49_RS17455 06bc8aafa080776910698cca6a27fab3 252 Pfam PF00455 DeoR C terminal sensor domain 74 231 8.0E-56 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 Gene3D G3DSA:3.40.630.30 294 440 2.5E-40 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 9 442 2.2E-197 T 10-03-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 Pfam PF00583 Acetyltransferase (GNAT) family 342 414 2.4E-7 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 SUPERFAMILY SSF55729 256 418 2.27E-18 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 442 234.82 T 10-03-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 Gene3D G3DSA:3.40.1160.10 24 291 6.1E-70 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 PIRSF PIRSF000423 1 442 6.1E-210 T 10-03-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 Pfam PF00696 Amino acid kinase family 26 268 3.3E-33 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS20950 10265a8932b7f94d9d3cdd29229df1d6 443 SUPERFAMILY SSF53633 6 291 3.07E-70 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS11010 6351cec6a6c59d9787fee4e6e170bf47 385 Gene3D G3DSA:1.10.10.60 339 358 6.3E-4 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11010 6351cec6a6c59d9787fee4e6e170bf47 385 Pfam PF13556 PucR C-terminal helix-turn-helix domain 323 381 2.9E-22 T 10-03-2017 IPR025736 PucR C-terminal helix-turn-helix domain RG49_RS11010 6351cec6a6c59d9787fee4e6e170bf47 385 Pfam PF05651 Putative sugar diacid recognition 6 138 5.8E-49 T 10-03-2017 IPR008599 Putative sugar diacid recognition RG49_RS17245 6b217f4d5af8d85ecdd645e88f396cda 198 SUPERFAMILY SSF53335 11 189 4.43E-53 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17245 6b217f4d5af8d85ecdd645e88f396cda 198 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 1 190 1.4E-79 T 10-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS17245 6b217f4d5af8d85ecdd645e88f396cda 198 PIRSF PIRSF004553 11 191 4.1E-62 T 10-03-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS17245 6b217f4d5af8d85ecdd645e88f396cda 198 Pfam PF03602 Conserved hypothetical protein 95 12 188 8.0E-63 T 10-03-2017 RG49_RS17245 6b217f4d5af8d85ecdd645e88f396cda 198 Gene3D G3DSA:3.40.50.150 5 194 5.7E-70 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17245 6b217f4d5af8d85ecdd645e88f396cda 198 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 124 130 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS20530 aceb0f412410ee45d060420b8f57c386 541 Pfam PF13478 XdhC Rossmann domain 106 247 2.9E-31 T 10-03-2017 IPR027051 XdhC Rossmann domain RG49_RS20530 aceb0f412410ee45d060420b8f57c386 541 TIGRFAM TIGR03309 matur_yqeB: selenium-dependent molybdenum hydroxylase system protein, YqeB family 271 526 6.5E-126 T 10-03-2017 IPR017695 Selenium-dependent molybdenum hydroxylase system protein, YqeB family RG49_RS20530 aceb0f412410ee45d060420b8f57c386 541 SUPERFAMILY SSF53187 407 489 2.09E-6 T 10-03-2017 RG49_RS20530 aceb0f412410ee45d060420b8f57c386 541 Gene3D G3DSA:2.40.50.100 433 481 6.1E-6 T 10-03-2017 RG49_RS20530 aceb0f412410ee45d060420b8f57c386 541 Pfam PF02625 XdhC and CoxI family 12 73 2.8E-16 T 10-03-2017 IPR003777 XdhC- CoxI RG49_RS23780 fee40d4ca185e3eaf50add88f5e77e13 285 SUPERFAMILY SSF52096 16 280 7.54E-79 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS23780 fee40d4ca185e3eaf50add88f5e77e13 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 10-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 RG49_RS23780 fee40d4ca185e3eaf50add88f5e77e13 285 Gene3D G3DSA:3.90.226.10 22 222 1.7E-70 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS23780 fee40d4ca185e3eaf50add88f5e77e13 285 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 284 55.624 T 10-03-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 RG49_RS23780 fee40d4ca185e3eaf50add88f5e77e13 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 279 8.5E-79 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS23780 fee40d4ca185e3eaf50add88f5e77e13 285 Gene3D G3DSA:1.10.12.10 223 273 2.3E-30 T 10-03-2017 IPR014748 Crontonase, C-terminal RG49_RS23780 fee40d4ca185e3eaf50add88f5e77e13 285 TIGRFAM TIGR01929 menB: naphthoate synthase 22 281 7.6E-152 T 10-03-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 2.6E-67 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 Gene3D G3DSA:1.10.520.20 3 104 1.9E-35 T 10-03-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 10-03-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.255 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 SUPERFAMILY SSF47928 3 102 1.14E-27 T 10-03-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 174 3.3E-50 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.1E-28 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.1E-28 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 1.1E-28 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.1E-28 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS15535 9493d28b2334a35fbf3a5971f94c0d6b 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 1.1E-28 T 10-03-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 SMART SM00859 5 123 1.0E-15 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 PIRSF PIRSF015689 1 315 1.8E-136 T 10-03-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 SUPERFAMILY SSF51735 1 155 5.63E-29 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 131 284 2.2E-63 T 10-03-2017 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 119 1.5E-13 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 Gene3D G3DSA:3.30.360.10 144 284 1.0E-74 T 10-03-2017 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 316 146.015 T 10-03-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 3 308 2.3E-142 T 10-03-2017 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 SUPERFAMILY SSF55347 131 284 8.5E-68 T 10-03-2017 RG49_RS09375 2cfc807776cae4addcaafe7630a822e3 316 Gene3D G3DSA:3.40.50.720 1 143 2.6E-75 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 SUPERFAMILY SSF53850 90 291 5.1E-47 T 10-03-2017 RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 Gene3D G3DSA:3.40.190.10 176 260 5.9E-23 T 10-03-2017 RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-13 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-13 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-13 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.9E-27 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 SUPERFAMILY SSF46785 4 111 4.96E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 Gene3D G3DSA:3.40.190.10 90 175 1.4E-22 T 10-03-2017 RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 Gene3D G3DSA:1.10.10.10 4 86 9.5E-32 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09445 4f3949c2d64173f0904786f1e9fb240f 299 Pfam PF03466 LysR substrate binding domain 88 290 2.6E-53 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 Gene3D G3DSA:3.90.79.10 3 126 1.0E-33 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 PRINTS PR01401 Mutator MutT protein signature 77 90 1.9E-16 T 10-03-2017 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 PRINTS PR01401 Mutator MutT protein signature 2 23 1.9E-16 T 10-03-2017 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 Pfam PF00293 NUDIX domain 5 125 3.7E-21 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 128 1.7E-69 T 10-03-2017 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.4E-8 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.4E-8 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS11360 ad01a70ae0aa1d45b730f946fb47abfd 129 SUPERFAMILY SSF55811 1 127 9.21E-34 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 Pfam PF00696 Amino acid kinase family 2 275 1.3E-27 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 Gene3D G3DSA:3.40.1160.10 1 293 7.9E-89 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 TIGRFAM TIGR00746 arcC: carbamate kinase 2 294 7.2E-125 T 10-03-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 PIRSF PIRSF000723 1 295 2.4E-108 T 10-03-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 SUPERFAMILY SSF53633 1 293 2.75E-69 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 PRINTS PR01469 Bacterial carbamate kinase signature 250 265 1.0E-47 T 10-03-2017 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 PRINTS PR01469 Bacterial carbamate kinase signature 151 170 1.0E-47 T 10-03-2017 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 PRINTS PR01469 Bacterial carbamate kinase signature 199 214 1.0E-47 T 10-03-2017 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 PRINTS PR01469 Bacterial carbamate kinase signature 72 90 1.0E-47 T 10-03-2017 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 PRINTS PR01469 Bacterial carbamate kinase signature 103 122 1.0E-47 T 10-03-2017 RG49_RS08475 032cd52064e172eaebfa8817ea4c1117 295 PRINTS PR01469 Bacterial carbamate kinase signature 42 61 1.0E-47 T 10-03-2017 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 ProSitePatterns PS00123 Alkaline phosphatase active site. 121 129 - T 10-03-2017 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 SMART SM00098 65 471 1.2E-240 T 10-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 SUPERFAMILY SSF53649 37 470 2.5E-141 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 Gene3D G3DSA:3.40.720.10 48 470 7.3E-142 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 Pfam PF00245 Alkaline phosphatase 64 430 7.4E-134 T 10-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 PRINTS PR00113 Alkaline phosphatase signature 121 136 1.2E-49 T 10-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 PRINTS PR00113 Alkaline phosphatase signature 64 84 1.2E-49 T 10-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 PRINTS PR00113 Alkaline phosphatase signature 320 349 1.2E-49 T 10-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 PRINTS PR00113 Alkaline phosphatase signature 221 231 1.2E-49 T 10-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS09220 81cfd3028acc52e80812134aa61a9cf6 471 PRINTS PR00113 Alkaline phosphatase signature 158 178 1.2E-49 T 10-03-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 RG49_RS22710 d8a3e3ff10107f51865e21b469fca63d 181 Pfam PF12838 4Fe-4S dicluster domain 39 89 3.3E-11 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS22710 d8a3e3ff10107f51865e21b469fca63d 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS22710 d8a3e3ff10107f51865e21b469fca63d 181 Gene3D G3DSA:3.30.70.20 6 84 1.4E-18 T 10-03-2017 RG49_RS22710 d8a3e3ff10107f51865e21b469fca63d 181 Gene3D G3DSA:3.30.70.20 85 121 5.7E-6 T 10-03-2017 RG49_RS22710 d8a3e3ff10107f51865e21b469fca63d 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS22710 d8a3e3ff10107f51865e21b469fca63d 181 SUPERFAMILY SSF54862 18 119 5.44E-21 T 10-03-2017 RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 6 241 5.4E-105 T 10-03-2017 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 SMART SM00866 96 236 1.7E-24 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 Gene3D G3DSA:1.10.10.10 8 82 1.8E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 9.0E-22 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 Pfam PF07702 UTRA domain 96 235 7.9E-31 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 SUPERFAMILY SSF64288 63 240 8.64E-37 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 SMART SM00345 17 75 1.6E-24 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 Gene3D G3DSA:3.40.1410.10 83 241 1.3E-46 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 1.9E-8 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 1.9E-8 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS13465 4e45dcbe238e34e6e6fd9737b30e93a0 241 SUPERFAMILY SSF46785 8 82 1.97E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22915 ea6be718a5715c764eca827299ccb955 467 PIRSF PIRSF012293 2 467 4.5E-214 T 10-03-2017 IPR009377 Ethanolamine utilisation EutA RG49_RS22915 ea6be718a5715c764eca827299ccb955 467 Pfam PF06277 Ethanolamine utilisation protein EutA 5 465 1.2E-179 T 10-03-2017 IPR009377 Ethanolamine utilisation EutA RG49_RS22915 ea6be718a5715c764eca827299ccb955 467 SUPERFAMILY SSF53067 8 266 1.3E-8 T 10-03-2017 RG49_RS22915 ea6be718a5715c764eca827299ccb955 467 Gene3D G3DSA:3.30.420.40 229 264 4.2E-6 T 10-03-2017 RG49_RS22915 ea6be718a5715c764eca827299ccb955 467 Gene3D G3DSA:3.30.420.40 148 178 4.2E-6 T 10-03-2017 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 SMART SM01240 7 347 2.2E-139 T 10-03-2017 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 338 3.5E-78 T 10-03-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 TIGRFAM TIGR01305 GMP_reduct_1: guanosine monophosphate reductase 2 344 1.7E-214 T 10-03-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 176 188 - T 10-03-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 Gene3D G3DSA:3.20.20.70 2 342 9.3E-112 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 SUPERFAMILY SSF51412 6 336 8.11E-100 T 10-03-2017 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 PIRSF PIRSF000235 1 347 7.1E-200 T 10-03-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 RG49_RS11340 e774b4bd360a8560af7557b6b005cc1c 347 Hamap MF_00596 GMP reductase [guaC]. 1 345 55.971 T 10-03-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 RG49_RS14740 2ab67f99e9eac535d94aa6e882142578 290 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 1 281 23.458 T 10-03-2017 IPR023679 Uncharacterised protein family UPF0761, bacterial RG49_RS14740 2ab67f99e9eac535d94aa6e882142578 290 Pfam PF03631 Virulence factor BrkB 29 274 7.4E-57 T 10-03-2017 IPR017039 Virulence factor BrkB RG49_RS14740 2ab67f99e9eac535d94aa6e882142578 290 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 18 275 3.0E-106 T 10-03-2017 IPR017039 Virulence factor BrkB RG49_RS14740 2ab67f99e9eac535d94aa6e882142578 290 PIRSF PIRSF035875 2 290 4.1E-73 T 10-03-2017 IPR017039 Virulence factor BrkB RG49_RS17640 37bc6b36a3c6a9ecadfa544006df132d 362 Gene3D G3DSA:3.40.50.1970 2 172 2.0E-67 T 10-03-2017 RG49_RS17640 37bc6b36a3c6a9ecadfa544006df132d 362 Gene3D G3DSA:1.20.1090.10 173 356 8.8E-68 T 10-03-2017 RG49_RS17640 37bc6b36a3c6a9ecadfa544006df132d 362 SUPERFAMILY SSF56796 4 356 1.31E-117 T 10-03-2017 RG49_RS17640 37bc6b36a3c6a9ecadfa544006df132d 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 358 43.403 T 10-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 RG49_RS17640 37bc6b36a3c6a9ecadfa544006df132d 362 Pfam PF01761 3-dehydroquinate synthase 67 325 3.6E-109 T 10-03-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 RG49_RS17640 37bc6b36a3c6a9ecadfa544006df132d 362 PIRSF PIRSF001455 10 360 2.6E-106 T 10-03-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 RG49_RS17640 37bc6b36a3c6a9ecadfa544006df132d 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 354 8.1E-123 T 10-03-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 RG49_RS16220 527e433349d66445e6c1224986f9ef24 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 10-03-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS16220 527e433349d66445e6c1224986f9ef24 55 SUPERFAMILY SSF57829 1 53 4.27E-20 T 10-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 RG49_RS16220 527e433349d66445e6c1224986f9ef24 55 Pfam PF00471 Ribosomal protein L33 7 53 8.7E-19 T 10-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS16220 527e433349d66445e6c1224986f9ef24 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 3.9E-28 T 10-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS16220 527e433349d66445e6c1224986f9ef24 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 15.857 T 10-03-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS21340 1474cda41f35e53ff58f26dc76c9adc5 159 Gene3D G3DSA:3.30.1330.50 1 156 1.4E-73 T 10-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 RG49_RS21340 1474cda41f35e53ff58f26dc76c9adc5 159 Pfam PF02542 YgbB family 1 154 1.2E-66 T 10-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 RG49_RS21340 1474cda41f35e53ff58f26dc76c9adc5 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.928 T 10-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 RG49_RS21340 1474cda41f35e53ff58f26dc76c9adc5 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 156 4.0E-72 T 10-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 RG49_RS21340 1474cda41f35e53ff58f26dc76c9adc5 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 10-03-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 RG49_RS21340 1474cda41f35e53ff58f26dc76c9adc5 159 SUPERFAMILY SSF69765 1 156 1.15E-66 T 10-03-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Gene3D G3DSA:3.40.1160.10 111 300 1.8E-68 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Gene3D G3DSA:3.40.1160.10 1 49 1.8E-68 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Gene3D G3DSA:3.40.50.720 464 635 1.4E-66 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 660 682 - T 10-03-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 SUPERFAMILY SSF53633 1 296 1.57E-73 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 PIRSF PIRSF000727 1 818 0.0 T 10-03-2017 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Pfam PF01842 ACT domain 324 376 7.1E-8 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 460 2.1E-153 T 10-03-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 605 2.1E-32 T 10-03-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 SUPERFAMILY SSF55347 614 798 3.79E-52 T 10-03-2017 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Gene3D G3DSA:3.30.360.10 636 792 7.6E-57 T 10-03-2017 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Pfam PF00742 Homoserine dehydrogenase 614 811 2.3E-48 T 10-03-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Pfam PF13840 ACT domain 393 453 5.5E-9 T 10-03-2017 IPR027795 GATS-like ACT domain RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 SUPERFAMILY SSF55021 303 381 1.68E-22 T 10-03-2017 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 Pfam PF00696 Amino acid kinase family 2 284 6.1E-46 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 SUPERFAMILY SSF55021 383 476 3.02E-22 T 10-03-2017 RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 SUPERFAMILY SSF51735 464 636 1.6E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11880 aa5ef26da8be8b26787aed802bc79247 820 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 10-03-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS09290 72f7f2011b970ac398c4b154464dbeb9 283 Gene3D G3DSA:3.60.130.10 2 281 8.4E-102 T 10-03-2017 RG49_RS09290 72f7f2011b970ac398c4b154464dbeb9 283 SUPERFAMILY SSF51197 5 281 3.48E-99 T 10-03-2017 RG49_RS09290 72f7f2011b970ac398c4b154464dbeb9 283 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 7 272 7.0E-67 T 10-03-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 RG49_RS11165 ecfab70b3f938bbc4d9204d884110491 447 Pfam PF00419 Fimbrial protein 284 446 2.2E-13 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11165 ecfab70b3f938bbc4d9204d884110491 447 PIRSF PIRSF033053 24 447 1.9E-173 T 10-03-2017 IPR017014 Fimbrial-like protein YadC RG49_RS11165 ecfab70b3f938bbc4d9204d884110491 447 Gene3D G3DSA:2.60.40.1090 279 447 6.7E-30 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11165 ecfab70b3f938bbc4d9204d884110491 447 SUPERFAMILY SSF49401 297 447 4.97E-15 T 10-03-2017 IPR008966 Adhesion domain RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 323 333 - T 10-03-2017 IPR017953 Carbohydrate kinase, predicted, conserved site RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 231 499 5.3E-99 T 10-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 17 220 7.8E-72 T 10-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 Pfam PF03853 YjeF-related protein N-terminus 40 199 1.6E-43 T 10-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 Pfam PF01256 Carbohydrate kinase 258 496 1.3E-81 T 10-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 SUPERFAMILY SSF53613 233 498 1.21E-75 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 234 503 23.373 T 10-03-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 Gene3D G3DSA:3.40.1190.20 241 498 5.4E-92 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 PIRSF PIRSF017184 15 506 2.2E-179 T 10-03-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 19 220 23.644 T 10-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 438 448 - T 10-03-2017 IPR017953 Carbohydrate kinase, predicted, conserved site RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 Gene3D G3DSA:3.40.50.10260 16 240 1.0E-69 T 10-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 RG49_RS13080 86a9b71887e93e95cd8b9b29fd67ff0c 515 SUPERFAMILY SSF64153 17 256 7.19E-64 T 10-03-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 RG49_RS02810 44405c17fce9977d276f82a86fc463ca 304 Pfam PF09160 FimH, mannose binding 27 171 6.1E-64 T 10-03-2017 IPR015243 FimH, mannose-binding domain RG49_RS02810 44405c17fce9977d276f82a86fc463ca 304 Gene3D G3DSA:2.60.40.1090 183 304 3.9E-31 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS02810 44405c17fce9977d276f82a86fc463ca 304 SUPERFAMILY SSF49401 184 304 2.53E-23 T 10-03-2017 IPR008966 Adhesion domain RG49_RS02810 44405c17fce9977d276f82a86fc463ca 304 Gene3D G3DSA:2.60.40.1090 23 182 1.3E-68 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS02810 44405c17fce9977d276f82a86fc463ca 304 SUPERFAMILY SSF49401 25 182 9.94E-67 T 10-03-2017 IPR008966 Adhesion domain RG49_RS09870 23f9b4ff7b14ca8d3db8d61b3844782c 232 Gene3D G3DSA:3.40.50.1390 44 144 3.0E-5 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09870 23f9b4ff7b14ca8d3db8d61b3844782c 232 Gene3D G3DSA:1.10.10.10 203 228 5.2E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09870 23f9b4ff7b14ca8d3db8d61b3844782c 232 Pfam PF00239 Resolvase, N terminal domain 94 188 4.4E-5 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09870 23f9b4ff7b14ca8d3db8d61b3844782c 232 Pfam PF07638 ECF sigma factor 185 227 7.5E-5 T 10-03-2017 IPR011517 RNA polymerase sigma-70 ECF-like RG49_RS09870 23f9b4ff7b14ca8d3db8d61b3844782c 232 SUPERFAMILY SSF53041 44 146 1.83E-6 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 SMART SM01382 124 251 7.5E-90 T 10-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 10-03-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 249 8.5E-56 T 10-03-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 Gene3D G3DSA:2.40.50.140 1 114 8.9E-51 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 47.144 T 10-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 272 3.6E-132 T 10-03-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 SUPERFAMILY SSF50249 3 125 5.14E-50 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 SUPERFAMILY SSF50104 126 269 1.44E-59 T 10-03-2017 IPR008991 Translation protein SH3-like domain RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 PIRSF PIRSF002158 12 273 1.1E-100 T 10-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 SMART SM01383 42 118 1.9E-48 T 10-03-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 7.7E-34 T 10-03-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 Gene3D G3DSA:4.10.950.10 196 272 1.8E-34 T 10-03-2017 IPR014726 Ribosomal protein L2, domain 3 RG49_RS18015 b8dda3d5223018c567ea5f3ca22e9fbc 273 Gene3D G3DSA:2.30.30.30 119 195 2.4E-34 T 10-03-2017 IPR014722 Ribosomal protein L2 domain 2 RG49_RS00475 fd56555bf7be884ab313102eaabc0485 167 Gene3D G3DSA:2.30.30.40 93 144 1.5E-9 T 10-03-2017 RG49_RS00475 fd56555bf7be884ab313102eaabc0485 167 SUPERFAMILY SSF50341 15 156 5.23E-39 T 10-03-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 RG49_RS00475 fd56555bf7be884ab313102eaabc0485 167 Pfam PF01584 CheW-like domain 18 154 7.4E-36 T 10-03-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 RG49_RS00475 fd56555bf7be884ab313102eaabc0485 167 Gene3D G3DSA:2.40.50.180 56 92 2.0E-9 T 10-03-2017 RG49_RS00475 fd56555bf7be884ab313102eaabc0485 167 SMART SM00260 14 151 6.2E-49 T 10-03-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 RG49_RS17445 63e1eaf319be5966e65f1807faa39795 108 SMART SM00450 7 102 1.1E-19 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS17445 63e1eaf319be5966e65f1807faa39795 108 SUPERFAMILY SSF52821 1 100 5.24E-27 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS17445 63e1eaf319be5966e65f1807faa39795 108 Pfam PF00581 Rhodanese-like domain 11 98 5.5E-13 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS17445 63e1eaf319be5966e65f1807faa39795 108 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 106 33.236 T 10-03-2017 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 RG49_RS17445 63e1eaf319be5966e65f1807faa39795 108 Gene3D G3DSA:3.40.250.10 2 101 3.3E-29 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS12545 6f0a42e8994f6a6fabfccbc4b709268a 155 Pfam PF07799 Protein of unknown function (DUF1643) 14 143 2.2E-39 T 10-03-2017 IPR012441 Protein of unknown function DUF1643 RG49_RS12545 6f0a42e8994f6a6fabfccbc4b709268a 155 PIRSF PIRSF032209 1 155 3.4E-69 T 10-03-2017 IPR016992 Uncharacterised conserved protein UCP032209 RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 1.2E-6 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 1.2E-6 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 SMART SM00387 374 480 6.2E-23 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 465 1.9E-11 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 SUPERFAMILY SSF47384 250 319 5.3E-5 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 Pfam PF08918 PhoQ Sensor 10 188 2.9E-85 T 10-03-2017 IPR015014 PhoQ Sensor GO:0000160|GO:0004673|GO:0005524|GO:0016020|GO:0018106|GO:0046872 RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 SUPERFAMILY SSF55874 336 476 7.07E-30 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 Pfam PF00672 HAMP domain 196 260 2.8E-7 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS04960 22e04226a9dc62b86f8c48c9d68a8e9c 486 Gene3D G3DSA:3.30.565.10 340 483 7.7E-31 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 3 348 8.5E-78 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 Pfam PF00460 Flagella basal body rod protein 5 35 3.3E-5 T 10-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 156 180 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 49 71 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 408 425 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 216 234 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 440 459 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 513 537 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 466 487 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 360 382 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 260 282 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 123 143 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 PRINTS PR01005 Flagellar hook-associated protein signature 11 34 1.3E-152 T 10-03-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 SUPERFAMILY SSF64518 103 545 2.88E-57 T 10-03-2017 RG49_RS05235 20cfdd7fda7c0816078c40680a78ed55 547 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 491 546 7.9E-8 T 10-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain RG49_RS14945 26c37380d6b7a5bc969d70bec5d24d67 483 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 466 5.7E-129 T 10-03-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 RG49_RS14945 26c37380d6b7a5bc969d70bec5d24d67 483 PIRSF PIRSF006247 1 483 2.2E-185 T 10-03-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 RG49_RS14945 26c37380d6b7a5bc969d70bec5d24d67 483 Pfam PF02386 Cation transport protein 37 477 4.9E-93 T 10-03-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 RG49_RS18645 e7b335ee1a6eca37cc7ce70d47aeab74 191 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 6 182 8.6E-53 T 10-03-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 RG49_RS18645 e7b335ee1a6eca37cc7ce70d47aeab74 191 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 9 183 1.9E-54 T 10-03-2017 IPR010664 Lipopolysaccharide assembly, LptC-related RG49_RS18645 e7b335ee1a6eca37cc7ce70d47aeab74 191 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 4 185 27.913 T 10-03-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 RG49_RS18645 e7b335ee1a6eca37cc7ce70d47aeab74 191 PIRSF PIRSF028513 1 186 2.8E-41 T 10-03-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 RG49_RS05220 2d8841d0af35a27834efe09cc09d3e22 106 Pfam PF10848 Protein of unknown function (DUF2655) 1 82 2.5E-61 T 10-03-2017 IPR020371 Uncharacterised protein family YceQ RG49_RS05220 2d8841d0af35a27834efe09cc09d3e22 106 ProDom PD078424 YCEQ 1 82 1.0E-43 T 10-03-2017 IPR020371 Uncharacterised protein family YceQ RG49_RS15245 e06926ccdb94ae48fd616fa82d3ad653 359 Hamap MF_01002 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase [wecF]. 1 359 64.449 T 10-03-2017 IPR009993 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase GO:0008417|GO:0009246|GO:0036065 RG49_RS15245 e06926ccdb94ae48fd616fa82d3ad653 359 Pfam PF07429 4-alpha-L-fucosyltransferase glycosyl transferase group 56 1 355 4.4E-182 T 10-03-2017 IPR009993 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase GO:0008417|GO:0009246|GO:0036065 RG49_RS24715 74427d61a075af6564e434addb29ec63 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS24715 74427d61a075af6564e434addb29ec63 249 SUPERFAMILY SSF51735 9 242 1.35E-65 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24715 74427d61a075af6564e434addb29ec63 249 Gene3D G3DSA:3.40.50.720 7 242 3.3E-67 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24715 74427d61a075af6564e434addb29ec63 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.0E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24715 74427d61a075af6564e434addb29ec63 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.0E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24715 74427d61a075af6564e434addb29ec63 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.0E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24715 74427d61a075af6564e434addb29ec63 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.0E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24715 74427d61a075af6564e434addb29ec63 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.0E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24715 74427d61a075af6564e434addb29ec63 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.0E-27 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24715 74427d61a075af6564e434addb29ec63 249 Pfam PF00106 short chain dehydrogenase 15 201 5.3E-57 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS09315 d8e0eb16a5b14b8582359d7f745954ca 223 Gene3D G3DSA:3.40.50.10320 16 222 1.4E-47 T 10-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 RG49_RS09315 d8e0eb16a5b14b8582359d7f745954ca 223 SUPERFAMILY SSF102588 17 220 1.57E-42 T 10-03-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 RG49_RS09315 d8e0eb16a5b14b8582359d7f745954ca 223 Pfam PF02585 GlcNAc-PI de-N-acetylase 20 141 3.5E-23 T 10-03-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 RG49_RS04150 3575f3e9a8fc7c545835472ec290d560 108 PIRSF PIRSF037511 1 108 1.4E-36 T 10-03-2017 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 RG49_RS04150 3575f3e9a8fc7c545835472ec290d560 108 Gene3D G3DSA:3.30.780.10 28 108 2.0E-35 T 10-03-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 RG49_RS04150 3575f3e9a8fc7c545835472ec290d560 108 Pfam PF01253 Translation initiation factor SUI1 32 101 8.6E-19 T 10-03-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 RG49_RS04150 3575f3e9a8fc7c545835472ec290d560 108 SUPERFAMILY SSF55159 6 104 4.45E-25 T 10-03-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 RG49_RS04150 3575f3e9a8fc7c545835472ec290d560 108 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 8 108 7.0E-40 T 10-03-2017 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 RG49_RS13985 adf91d32ef2d4525384730927b6ee9a0 578 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 9 566 9.3E-244 T 10-03-2017 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 RG49_RS13985 adf91d32ef2d4525384730927b6ee9a0 578 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 9 573 0.0 T 10-03-2017 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 RG49_RS13985 adf91d32ef2d4525384730927b6ee9a0 578 PIRSF PIRSF000719 1 575 1.5E-300 T 10-03-2017 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 RG49_RS13985 adf91d32ef2d4525384730927b6ee9a0 578 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 1 570 43.539 T 10-03-2017 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 SUPERFAMILY SSF47598 1 45 3.6E-12 T 10-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 Gene3D G3DSA:1.10.1220.10 1 46 1.1E-23 T 10-03-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 42 1.5E-11 T 10-03-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 SUPERFAMILY SSF55021 53 132 2.52E-26 T 10-03-2017 RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 Gene3D G3DSA:3.30.70.1150 50 132 7.0E-34 T 10-03-2017 RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 Pfam PF08753 NikR C terminal nickel binding domain 54 127 1.2E-27 T 10-03-2017 IPR014864 Transcription factor, NikR, nickel binding C-terminal RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 TIGRFAM TIGR02793 nikR: nickel-responsive transcriptional regulator NikR 2 130 8.0E-68 T 10-03-2017 IPR014160 Nickel-responsive transcriptional regulator NikR, proteobacteria GO:0010045|GO:0016151 RG49_RS17165 6d977bb96b25187abc5348661bf9f009 133 Hamap MF_00476 Putative nickel-responsive regulator [nikR]. 1 131 27.936 T 10-03-2017 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 RG49_RS13540 d3aabd2bfef2d44bcfe52a4c266a95fb 296 Gene3D G3DSA:3.40.50.10490 110 277 6.1E-37 T 10-03-2017 RG49_RS13540 d3aabd2bfef2d44bcfe52a4c266a95fb 296 Pfam PF01418 Helix-turn-helix domain, rpiR family 15 90 1.1E-25 T 10-03-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 RG49_RS13540 d3aabd2bfef2d44bcfe52a4c266a95fb 296 SUPERFAMILY SSF46689 17 89 6.09E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13540 d3aabd2bfef2d44bcfe52a4c266a95fb 296 Gene3D G3DSA:1.10.10.10 20 89 3.7E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13540 d3aabd2bfef2d44bcfe52a4c266a95fb 296 Pfam PF01380 SIS domain 138 266 1.2E-32 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS13540 d3aabd2bfef2d44bcfe52a4c266a95fb 296 SUPERFAMILY SSF53697 104 288 1.7E-40 T 10-03-2017 RG49_RS13175 4c57b23ab62f3064487d3fd7f5504aa8 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.2E-33 T 10-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 RG49_RS13175 4c57b23ab62f3064487d3fd7f5504aa8 105 SUPERFAMILY SSF103481 5 103 9.42E-21 T 10-03-2017 RG49_RS10375 e4bc926217772b44d17429ec68679808 217 TIGRFAM TIGR01712 phage_N6A_met: phage N-6-adenine-methyltransferase 14 197 4.1E-77 T 10-03-2017 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 RG49_RS10375 e4bc926217772b44d17429ec68679808 217 Pfam PF05869 DNA N-6-adenine-methyltransferase (Dam) 17 201 2.3E-62 T 10-03-2017 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 RG49_RS21745 a8caa264b5687bad9e7a13fb2c1eb459 134 Gene3D G3DSA:1.10.287.1050 1 58 3.9E-23 T 10-03-2017 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 RG49_RS21745 a8caa264b5687bad9e7a13fb2c1eb459 134 SUPERFAMILY SSF81273 92 134 1.06E-11 T 10-03-2017 RG49_RS21745 a8caa264b5687bad9e7a13fb2c1eb459 134 Gene3D G3DSA:4.10.430.10 91 134 3.1E-26 T 10-03-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 RG49_RS21745 a8caa264b5687bad9e7a13fb2c1eb459 134 SUPERFAMILY SSF81273 3 58 2.94E-18 T 10-03-2017 RG49_RS21745 a8caa264b5687bad9e7a13fb2c1eb459 134 Pfam PF00816 H-NS histone family 38 128 6.2E-20 T 10-03-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 RG49_RS21745 a8caa264b5687bad9e7a13fb2c1eb459 134 SMART SM00528 87 134 5.3E-27 T 10-03-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 RG49_RS21745 a8caa264b5687bad9e7a13fb2c1eb459 134 PIRSF PIRSF002096 1 134 1.0E-55 T 10-03-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 SUPERFAMILY SSF48208 55 547 1.62E-148 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 Pfam PF01204 Trehalase 70 546 3.3E-166 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 ProSitePatterns PS00927 Trehalase signature 1. 165 178 - T 10-03-2017 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 Hamap MF_01059 Cytoplasmic trehalase [treF]. 34 549 80.38 T 10-03-2017 IPR023715 Trehalase, cytoplasmic GO:0004555|GO:0005737|GO:0005993|GO:0071474 KEGG: 00500+3.2.1.28 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 452 468 5.1E-46 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 389 405 5.1E-46 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 314 331 5.1E-46 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 530 543 5.1E-46 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 346 363 5.1E-46 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 207 225 5.1E-46 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 281 298 5.1E-46 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS16935 9f913760ae5fc270b0bcfd6304847fad 549 ProSitePatterns PS00928 Trehalase signature 2. 459 468 - T 10-03-2017 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 PRINTS PR00973 Ribosomal protein S17 family signature 24 47 4.8E-14 T 10-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 PRINTS PR00973 Ribosomal protein S17 family signature 56 66 4.8E-14 T 10-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 PRINTS PR00973 Ribosomal protein S17 family signature 66 73 4.8E-14 T 10-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 SUPERFAMILY SSF50249 5 82 7.28E-34 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 76 7.0E-36 T 10-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 ProSitePatterns PS00056 Ribosomal protein S17 signature. 56 68 - T 10-03-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 Gene3D G3DSA:2.40.50.140 6 82 4.4E-37 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 Pfam PF00366 Ribosomal protein S17 10 76 1.7E-34 T 10-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 76 1.0E-38 T 10-03-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18045 269efc68924760e54d96bb26e1d8210a 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 81 26.39 T 10-03-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 289 4.3E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 289 305 4.3E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 Pfam PF12833 Helix-turn-helix domain 229 305 1.2E-21 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 SMART SM00342 222 305 6.9E-32 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 Pfam PF02311 AraC-like ligand binding domain 52 175 2.1E-22 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 SUPERFAMILY SSF46689 258 306 9.41E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 301 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 Hamap MF_01533 HTH-type transcriptional activator RhaR [rhaR]. 31 312 52.388 T 10-03-2017 IPR023699 Transcription activator HTH, RhaR GO:0003700|GO:0005737|GO:0019299|GO:0045893 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 SUPERFAMILY SSF51182 37 151 1.42E-14 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 Gene3D G3DSA:1.10.10.60 201 258 1.1E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 SUPERFAMILY SSF46689 207 257 9.86E-5 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 Gene3D G3DSA:2.60.120.280 57 192 4.7E-14 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS14615 e4d3e8ad38b012ab626f91f1e62fd6e0 312 Gene3D G3DSA:1.10.10.60 259 306 8.2E-16 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Gene3D G3DSA:3.30.230.10 220 392 1.2E-78 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 SUPERFAMILY SSF56719 730 795 8.11E-87 T 10-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 SUPERFAMILY SSF56719 394 560 8.11E-87 T 10-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 732 793 2.6E-30 T 10-03-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Pfam PF00204 DNA gyrase B 221 390 2.8E-59 T 10-03-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Gene3D G3DSA:3.30.565.10 15 218 1.7E-92 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 ProSitePatterns PS00177 DNA topoisomerase II signature. 422 430 - T 10-03-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 SMART SM00433 35 797 2.8E-283 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 SUPERFAMILY SSF55874 4 220 1.22E-77 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Pfam PF01751 Toprim domain 419 531 4.0E-18 T 10-03-2017 IPR006171 Toprim domain RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 804 117.127 T 10-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 487 503 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 525 537 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 736 752 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 113 127 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 268 281 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 505 522 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 35 50 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 70 83 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR00418 DNA topoisomerase II family signature 420 434 5.8E-71 T 10-03-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 804 0.0 T 10-03-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Gene3D G3DSA:3.40.50.670 404 550 1.2E-101 T 10-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Gene3D G3DSA:3.40.50.670 718 786 1.2E-101 T 10-03-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 SMART SM00387 31 175 2.6E-30 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 SUPERFAMILY SSF54211 221 392 5.12E-62 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 174 6.7E-24 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 360 374 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 470 479 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 196 209 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 312 328 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 181 196 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 757 769 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 773 789 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 5 15 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 220 242 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS15730 162027c62ad186be3a31257d5026d55d 804 PRINTS PR01159 DNA gyrase subunit B signature 374 394 1.6E-80 T 10-03-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 RG49_RS14570 dfa9e01deeb9b70c1ffa4b789a91d914 166 Pfam PF07813 LTXXQ motif family protein 41 135 7.4E-22 T 10-03-2017 IPR012899 LTXXQ motif family protein GO:0042597 RG49_RS14570 dfa9e01deeb9b70c1ffa4b789a91d914 166 PIRSF PIRSF034445 2 146 5.5E-31 T 10-03-2017 IPR012899 LTXXQ motif family protein GO:0042597 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 Gene3D G3DSA:2.30.42.10 252 334 6.2E-23 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 Pfam PF03572 Peptidase family S41 356 529 2.2E-53 T 10-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 SUPERFAMILY SSF52096 194 264 2.49E-68 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 SUPERFAMILY SSF52096 350 537 2.49E-68 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 SUPERFAMILY SSF50156 219 345 6.03E-16 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 Gene3D G3DSA:3.30.750.44 199 251 7.3E-4 T 10-03-2017 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 240 320 6.0E-15 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 194 551 5.4E-131 T 10-03-2017 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 SMART SM00228 246 323 1.1E-9 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 Gene3D G3DSA:3.90.226.10 335 533 1.3E-67 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 Gene3D G3DSA:3.90.226.10 646 675 1.3E-67 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 SMART SM00245 326 531 3.6E-82 T 10-03-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 RG49_RS00800 ac2fa0e6146f3d8e5c55152fc32081ac 682 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 536 667 8.4E-40 T 10-03-2017 IPR020992 Tail specific protease, C-terminal RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 13 37 5.4E-6 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 59 204 3.2E-32 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 156 180 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 211 228 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 67 91 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 185 208 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 113 136 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 253 279 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 229 247 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 44 66 3.6E-69 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 Gene3D G3DSA:4.10.480.10 224 299 1.2E-31 T 10-03-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 2 365 2.8E-197 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 224 302 1.2E-26 T 10-03-2017 IPR027394 Cytochrome-c3 hydrogenase, C-terminal RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 PIRSF PIRSF000310 2 367 1.5E-136 T 10-03-2017 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 Gene3D G3DSA:3.40.50.700 47 222 2.0E-60 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS19775 557bfd076e53f845aacbe58a6a58980b 372 SUPERFAMILY SSF56770 44 302 1.07E-84 T 10-03-2017 RG49_RS13895 24cf204035ae320475d91045f211b661 491 Pfam PF00083 Sugar (and other) transporter 14 478 1.8E-149 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 Gene3D G3DSA:1.20.1250.20 279 479 1.0E-24 T 10-03-2017 RG49_RS13895 24cf204035ae320475d91045f211b661 491 Gene3D G3DSA:1.20.1250.20 46 227 4.6E-19 T 10-03-2017 RG49_RS13895 24cf204035ae320475d91045f211b661 491 PRINTS PR00171 Sugar transporter signature 21 31 2.2E-28 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 PRINTS PR00171 Sugar transporter signature 373 394 2.2E-28 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 PRINTS PR00171 Sugar transporter signature 288 298 2.2E-28 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 PRINTS PR00171 Sugar transporter signature 130 149 2.2E-28 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 PRINTS PR00171 Sugar transporter signature 396 408 2.2E-28 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 SUPERFAMILY SSF103473 6 475 2.75E-62 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS13895 24cf204035ae320475d91045f211b661 491 ProSitePatterns PS00216 Sugar transport proteins signature 1. 332 349 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS13895 24cf204035ae320475d91045f211b661 491 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 1 474 4.7E-164 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 Pfam PF03797 Autotransporter beta-domain 883 1150 1.7E-35 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 SUPERFAMILY SSF51126 448 825 2.07E-43 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 479 509 1.0E-9 T 10-03-2017 IPR013425 Autotransporter-associated beta strand repeat RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 SMART SM00869 881 1154 5.9E-36 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 Gene3D G3DSA:2.40.128.130 839 1165 2.6E-68 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 716 1165 9.3E-97 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 Pfam PF03212 Pertactin 729 818 6.1E-7 T 10-03-2017 IPR004899 Pertactin, central region RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 SUPERFAMILY SSF103515 846 1165 7.32E-45 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 Gene3D G3DSA:2.160.20.20 590 829 2.2E-38 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 Pfam PF12951 Passenger-associated-transport-repeat 643 669 0.013 T 10-03-2017 IPR013425 Autotransporter-associated beta strand repeat RG49_RS16030 b9b84dab616f2f20c3b59e8ed6ee8dfb 1165 Pfam PF12951 Passenger-associated-transport-repeat 480 509 1.1E-6 T 10-03-2017 IPR013425 Autotransporter-associated beta strand repeat RG49_RS23775 b2e52db3e32ed6c1dfc3a976d3e128af 252 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 15 250 2.3E-79 T 10-03-2017 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 RG49_RS23775 b2e52db3e32ed6c1dfc3a976d3e128af 252 SUPERFAMILY SSF53474 9 250 3.71E-39 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS23775 b2e52db3e32ed6c1dfc3a976d3e128af 252 Gene3D G3DSA:3.40.50.1820 8 251 1.2E-54 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS23775 b2e52db3e32ed6c1dfc3a976d3e128af 252 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 4 251 32.465 T 10-03-2017 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 RG49_RS23775 b2e52db3e32ed6c1dfc3a976d3e128af 252 Pfam PF12697 Alpha/beta hydrolase family 17 244 2.4E-19 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS16310 7d9abda79d08a0ec43d52f3e831f3d8d 285 TIGRFAM TIGR02192 HtrL_YibB: protein YibB 1 277 2.2E-132 T 10-03-2017 IPR011735 HtrL protein RG49_RS16310 7d9abda79d08a0ec43d52f3e831f3d8d 285 Pfam PF09612 Bacterial protein of unknown function (HtrL_YibB) 4 267 7.1E-111 T 10-03-2017 IPR011735 HtrL protein RG49_RS02530 6ca775b4a96bbd8c143d2f0e432a592e 172 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 24 169 4.1E-61 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS02530 6ca775b4a96bbd8c143d2f0e432a592e 172 Pfam PF02464 Competence-damaged protein 18 171 3.6E-48 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS02530 6ca775b4a96bbd8c143d2f0e432a592e 172 SUPERFAMILY SSF142433 16 171 7.85E-46 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS02530 6ca775b4a96bbd8c143d2f0e432a592e 172 Gene3D G3DSA:3.90.950.20 14 171 1.7E-46 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 SUPERFAMILY SSF52096 30 181 1.19E-31 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 SUPERFAMILY SSF52096 212 287 1.19E-31 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 PIRSF PIRSF001217 8 618 5.4E-232 T 10-03-2017 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 Pfam PF01343 Peptidase family S49 141 295 1.4E-46 T 10-03-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 Pfam PF01343 Peptidase family S49 392 543 2.2E-54 T 10-03-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 609 3.9E-286 T 10-03-2017 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 Gene3D G3DSA:3.90.226.10 30 177 3.1E-70 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 Gene3D G3DSA:3.90.226.10 220 316 3.1E-70 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 Gene3D G3DSA:3.90.226.10 469 559 2.3E-69 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 Gene3D G3DSA:3.90.226.10 323 432 2.3E-69 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 SUPERFAMILY SSF52096 321 440 7.69E-43 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 SUPERFAMILY SSF52096 468 530 7.69E-43 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS01155 2c3f5948771b7ab88e28b04a84323bc1 618 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 335 541 3.2E-53 T 10-03-2017 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 RG49_RS21445 e0ef488a5fde62cb45115f4e5aaf1c66 116 PIRSF PIRSF004761 1 116 1.7E-36 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS21445 e0ef488a5fde62cb45115f4e5aaf1c66 116 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 114 22.726 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS21445 e0ef488a5fde62cb45115f4e5aaf1c66 116 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 10-03-2017 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site RG49_RS21445 e0ef488a5fde62cb45115f4e5aaf1c66 116 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 113 8.4E-30 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS21445 e0ef488a5fde62cb45115f4e5aaf1c66 116 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 116 3.0E-44 T 10-03-2017 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 RG49_RS10760 a883a058ed9160569ff9f9f431d5a057 266 Gene3D G3DSA:3.60.10.10 39 233 5.7E-7 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS10760 a883a058ed9160569ff9f9f431d5a057 266 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 49 252 3.4E-9 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS10760 a883a058ed9160569ff9f9f431d5a057 266 SUPERFAMILY SSF56219 44 260 1.96E-26 T 10-03-2017 IPR005135 Endonuclease/exonuclease/phosphatase RG49_RS10760 a883a058ed9160569ff9f9f431d5a057 266 Hamap MF_01119 UPF0294 protein YafD [yafD]. 1 260 54.24 T 10-03-2017 IPR022958 Uncharacterised protein family UPF0294 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 84 1.4E-30 T 10-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 1.1E-48 T 10-03-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 SUPERFAMILY SSF46604 88 137 1.36E-15 T 10-03-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 133 1.1E-13 T 10-03-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 Gene3D G3DSA:1.20.5.440 92 134 2.8E-25 T 10-03-2017 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 SUPERFAMILY SSF51344 3 86 2.09E-25 T 10-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 Gene3D G3DSA:2.60.15.10 3 91 2.8E-30 T 10-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 90 4.0E-41 T 10-03-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS15555 9697dece7ffc23f6ca461bc452f22532 139 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 21.752 T 10-03-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 Pfam PF00696 Amino acid kinase family 4 296 5.5E-26 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 SUPERFAMILY SSF53633 3 313 3.93E-73 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 3.5E-60 T 10-03-2017 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PRINTS PR01469 Bacterial carbamate kinase signature 215 230 3.5E-60 T 10-03-2017 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PRINTS PR01469 Bacterial carbamate kinase signature 111 130 3.5E-60 T 10-03-2017 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PRINTS PR01469 Bacterial carbamate kinase signature 270 285 3.5E-60 T 10-03-2017 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 3.5E-60 T 10-03-2017 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 3.5E-60 T 10-03-2017 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 3.5E-60 T 10-03-2017 RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 Gene3D G3DSA:3.40.1160.10 1 315 1.2E-99 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS09525 3aa7f13532e317e3624dfed3f5e93336 316 PIRSF PIRSF000723 1 315 7.0E-131 T 10-03-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 RG49_RS05815 2604795b96b4bfcd897590422134b767 378 PIRSF PIRSF000267 2 377 2.1E-117 T 10-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 RG49_RS05815 2604795b96b4bfcd897590422134b767 378 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 361 1.5E-97 T 10-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 RG49_RS05815 2604795b96b4bfcd897590422134b767 378 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 378 5.9E-199 T 10-03-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 RG49_RS11300 ee01be8c1c7402256b5d426934c9b15c 457 PIRSF PIRSF006060 1 453 9.1E-82 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS11300 ee01be8c1c7402256b5d426934c9b15c 457 ProSitePatterns PS00218 Amino acid permeases signature. 44 74 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS11300 ee01be8c1c7402256b5d426934c9b15c 457 Pfam PF00324 Amino acid permease 19 454 1.1E-131 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 SUPERFAMILY SSF54862 26 262 4.92E-72 T 10-03-2017 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 290 1.2E-145 T 10-03-2017 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Pfam PF12800 4Fe-4S binding domain 38 50 0.11 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 PIRSF PIRSF036298 1 294 6.0E-164 T 10-03-2017 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 3.5E-20 T 10-03-2017 IPR015246 Formate dehydrogenase, transmembrane RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Gene3D G3DSA:3.30.70.20 104 137 1.7E-11 T 10-03-2017 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Pfam PF13247 4Fe-4S dicluster domain 92 188 1.1E-25 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Gene3D G3DSA:3.30.70.20 173 227 4.4E-37 T 10-03-2017 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Gene3D G3DSA:3.30.70.20 30 103 4.4E-37 T 10-03-2017 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Gene3D G3DSA:3.30.70.20 138 172 1.3E-15 T 10-03-2017 RG49_RS02965 75cef5c27f840a1ec1b9d27616b76458 294 Gene3D G3DSA:1.20.5.480 247 294 2.8E-25 T 10-03-2017 RG49_RS16790 462381d1f9177a9af316dab6fb71b1f4 300 SUPERFAMILY SSF161098 93 280 6.41E-29 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16790 462381d1f9177a9af316dab6fb71b1f4 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 69 1.5E-16 T 10-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain RG49_RS16790 462381d1f9177a9af316dab6fb71b1f4 300 Gene3D G3DSA:1.10.3720.10 88 296 2.4E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16790 462381d1f9177a9af316dab6fb71b1f4 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 299 1.3E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS11725 fd663c367297cadbd81e4c8b4dbfb5a7 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 284 2.4E-100 T 10-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 RG49_RS11725 fd663c367297cadbd81e4c8b4dbfb5a7 316 Pfam PF02401 LytB protein 3 282 1.5E-92 T 10-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 RG49_RS11725 fd663c367297cadbd81e4c8b4dbfb5a7 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 286 38.131 T 10-03-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 RG49_RS18965 f099bffd72d19c88f44a6c676ea178bf 158 SUPERFAMILY SSF52728 5 156 2.35E-48 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS18965 f099bffd72d19c88f44a6c676ea178bf 158 Gene3D G3DSA:3.40.35.10 5 156 2.8E-54 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS18965 f099bffd72d19c88f44a6c676ea178bf 158 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 5 155 1.1E-71 T 10-03-2017 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 RG49_RS18965 f099bffd72d19c88f44a6c676ea178bf 158 Pfam PF03830 PTS system sorbose subfamily IIB component 6 153 2.2E-48 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS15740 5ead7332b2e590892871a22450e06376 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 1.0E-31 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS15740 5ead7332b2e590892871a22450e06376 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 1.1E-76 T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS15740 5ead7332b2e590892871a22450e06376 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 264 1.9E-67 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15740 5ead7332b2e590892871a22450e06376 270 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 10-03-2017 RG49_RS15740 5ead7332b2e590892871a22450e06376 270 Gene3D G3DSA:3.30.1240.10 88 183 3.1E-41 T 10-03-2017 RG49_RS15740 5ead7332b2e590892871a22450e06376 270 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS15740 5ead7332b2e590892871a22450e06376 270 Gene3D G3DSA:3.40.50.1000 1 76 4.0E-61 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15740 5ead7332b2e590892871a22450e06376 270 Gene3D G3DSA:3.40.50.1000 184 269 4.0E-61 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15740 5ead7332b2e590892871a22450e06376 270 SUPERFAMILY SSF56784 1 269 1.88E-76 T 10-03-2017 IPR023214 HAD-like domain RG49_RS03375 5e896df18507e2cd5ea2c47c20ff7323 554 Gene3D G3DSA:3.40.50.150 366 535 3.9E-13 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS03375 5e896df18507e2cd5ea2c47c20ff7323 554 Pfam PF12147 Putative methyltransferase 244 551 3.2E-149 T 10-03-2017 IPR022744 Methyltransferase domain, putative RG49_RS03375 5e896df18507e2cd5ea2c47c20ff7323 554 SUPERFAMILY SSF53474 70 250 9.2E-17 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS03375 5e896df18507e2cd5ea2c47c20ff7323 554 Gene3D G3DSA:3.40.50.1820 64 251 3.8E-18 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS03375 5e896df18507e2cd5ea2c47c20ff7323 554 Pfam PF12146 Serine aminopeptidase, S33 75 233 1.5E-38 T 10-03-2017 IPR022742 Serine aminopeptidase, S33 RG49_RS03375 5e896df18507e2cd5ea2c47c20ff7323 554 SUPERFAMILY SSF53335 354 534 1.19E-16 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00830 7f0d0bca562eeaf47b0b6aa2a0147d5b 95 Pfam PF13974 YebO-like protein 16 95 1.6E-32 T 10-03-2017 IPR025594 YebO-like protein RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 166 313 8.9E-26 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 Gene3D G3DSA:3.90.650.10 165 316 2.6E-24 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 53 152 2.2E-15 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 SUPERFAMILY SSF56042 163 331 1.5E-39 T 10-03-2017 IPR010918 AIR synthase-related protein, C-terminal domain RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 3 336 3.3E-141 T 10-03-2017 IPR011854 Hydrogenase expression/formation protein HypE RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 SUPERFAMILY SSF55326 3 156 1.64E-32 T 10-03-2017 RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 PIRSF PIRSF005644 1 336 4.2E-123 T 10-03-2017 IPR011854 Hydrogenase expression/formation protein HypE RG49_RS21425 b92192fa57724aa81b9ae952e5d42346 336 Gene3D G3DSA:3.30.1330.10 15 155 5.4E-24 T 10-03-2017 IPR016188 PurM-like, N-terminal domain RG49_RS03825 050219775973303342f92cb9f00a4d17 187 Pfam PF01713 Smr domain 89 169 1.5E-18 T 10-03-2017 IPR002625 Smr domain RG49_RS03825 050219775973303342f92cb9f00a4d17 187 SUPERFAMILY SSF160443 86 169 3.4E-12 T 10-03-2017 IPR002625 Smr domain RG49_RS03825 050219775973303342f92cb9f00a4d17 187 SMART SM00463 85 169 1.0E-18 T 10-03-2017 IPR002625 Smr domain RG49_RS25200 ed1769680a83d438741ed552eb5e2fe5 359 Gene3D G3DSA:1.10.1610.10 1 73 2.8E-31 T 10-03-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25200 ed1769680a83d438741ed552eb5e2fe5 359 SUPERFAMILY SSF52733 6 344 3.4E-112 T 10-03-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25200 ed1769680a83d438741ed552eb5e2fe5 359 Gene3D G3DSA:3.40.50.10210 74 330 4.0E-103 T 10-03-2017 RG49_RS25200 ed1769680a83d438741ed552eb5e2fe5 359 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 15 346 4.3E-118 T 10-03-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25200 ed1769680a83d438741ed552eb5e2fe5 359 Pfam PF02277 Phosphoribosyltransferase 11 345 4.0E-119 T 10-03-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25200 ed1769680a83d438741ed552eb5e2fe5 359 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 13 349 34.031 T 10-03-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS13575 9abdad21bf235621e318ea6ded2a0321 91 Pfam PF17090 Uncharacterised protein family 30 91 1.2E-15 T 10-03-2017 IPR031381 Uncharacterised protein YtcA RG49_RS23830 65b55bf64082c8af9e8c57b2ef97b800 379 SUPERFAMILY SSF53383 4 376 5.65E-115 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS23830 65b55bf64082c8af9e8c57b2ef97b800 379 Gene3D G3DSA:3.90.1150.10 253 378 2.5E-43 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS23830 65b55bf64082c8af9e8c57b2ef97b800 379 PIRSF PIRSF000390 1 379 3.2E-114 T 10-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase RG49_RS23830 65b55bf64082c8af9e8c57b2ef97b800 379 Hamap MF_01167 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase [arnB]. 1 379 69.919 T 10-03-2017 IPR022850 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase, ArnB GO:0008483 KEGG: 00520+2.6.1.87 RG49_RS23830 65b55bf64082c8af9e8c57b2ef97b800 379 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 373 1.3E-137 T 10-03-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase RG49_RS23830 65b55bf64082c8af9e8c57b2ef97b800 379 Gene3D G3DSA:3.40.640.10 4 250 6.2E-88 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS18475 b07f5eb7a050c52d00c36de294a6ba3f 212 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 194 1.7E-13 T 10-03-2017 IPR004046 Glutathione S-transferase, C-terminal RG49_RS18475 b07f5eb7a050c52d00c36de294a6ba3f 212 Gene3D G3DSA:3.40.30.10 7 101 1.8E-29 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS18475 b07f5eb7a050c52d00c36de294a6ba3f 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 10 81 5.5E-20 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS18475 b07f5eb7a050c52d00c36de294a6ba3f 212 SUPERFAMILY SSF47616 82 208 1.42E-27 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS18475 b07f5eb7a050c52d00c36de294a6ba3f 212 Gene3D G3DSA:1.20.1050.10 102 208 1.3E-17 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS18475 b07f5eb7a050c52d00c36de294a6ba3f 212 SUPERFAMILY SSF52833 7 90 2.76E-23 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS23685 ae0700384201c95c88810a02dd3a21f9 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 60 71 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS23685 ae0700384201c95c88810a02dd3a21f9 180 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 16 137 7.2E-52 T 10-03-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23685 ae0700384201c95c88810a02dd3a21f9 180 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 163 26.93 T 10-03-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23685 ae0700384201c95c88810a02dd3a21f9 180 Gene3D G3DSA:3.30.70.20 27 117 1.0E-18 T 10-03-2017 RG49_RS23685 ae0700384201c95c88810a02dd3a21f9 180 Pfam PF12838 4Fe-4S dicluster domain 59 113 1.3E-11 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS23685 ae0700384201c95c88810a02dd3a21f9 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS23685 ae0700384201c95c88810a02dd3a21f9 180 SUPERFAMILY SSF54862 33 153 5.44E-29 T 10-03-2017 RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 SMART SM00357 6 70 2.4E-30 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 SUPERFAMILY SSF50249 3 69 6.64E-26 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 2.8E-33 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 Gene3D G3DSA:2.40.50.140 5 68 7.9E-32 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 PRINTS PR00050 Cold shock protein signature 7 22 9.0E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 PRINTS PR00050 Cold shock protein signature 43 61 9.0E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 PRINTS PR00050 Cold shock protein signature 28 37 9.0E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 PIRSF PIRSF002599 1 70 3.5E-25 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS05760 662e2c654a4d1fc5062f4e29d8747029 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS11590 1701af2fd299773270f7ff290d954757 271 SUPERFAMILY SSF46565 131 267 4.29E-31 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11590 1701af2fd299773270f7ff290d954757 271 SMART SM00271 204 269 5.2E-17 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11590 1701af2fd299773270f7ff290d954757 271 Gene3D G3DSA:1.10.287.110 209 267 2.7E-14 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11590 1701af2fd299773270f7ff290d954757 271 Hamap MF_01153 Co-chaperone protein DjlA [djlA]. 3 270 38.975 T 10-03-2017 IPR023749 Co-chaperone DjlA GO:0051087 RG49_RS11590 1701af2fd299773270f7ff290d954757 271 Pfam PF00226 DnaJ domain 208 267 7.1E-11 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11590 1701af2fd299773270f7ff290d954757 271 PRINTS PR00625 DnaJ domain signature 207 225 1.7E-7 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11590 1701af2fd299773270f7ff290d954757 271 PRINTS PR00625 DnaJ domain signature 249 269 1.7E-7 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11590 1701af2fd299773270f7ff290d954757 271 PRINTS PR00625 DnaJ domain signature 225 240 1.7E-7 T 10-03-2017 IPR001623 DnaJ domain RG49_RS11590 1701af2fd299773270f7ff290d954757 271 Pfam PF05099 Tellurite resistance protein TerB 47 170 4.9E-10 T 10-03-2017 IPR007791 Co-chaperone DjlA, N-terminal RG49_RS11590 1701af2fd299773270f7ff290d954757 271 Gene3D G3DSA:1.10.3680.10 22 208 3.5E-27 T 10-03-2017 IPR029024 TerB-like RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 SUPERFAMILY SSF53633 3 308 9.56E-84 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 Pfam PF00696 Amino acid kinase family 3 288 7.6E-30 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 Gene3D G3DSA:3.40.1160.10 2 308 1.3E-108 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PIRSF PIRSF000723 1 310 1.0E-122 T 10-03-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PRINTS PR01469 Bacterial carbamate kinase signature 264 279 1.4E-65 T 10-03-2017 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PRINTS PR01469 Bacterial carbamate kinase signature 179 197 1.4E-65 T 10-03-2017 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PRINTS PR01469 Bacterial carbamate kinase signature 73 91 1.4E-65 T 10-03-2017 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PRINTS PR01469 Bacterial carbamate kinase signature 108 127 1.4E-65 T 10-03-2017 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PRINTS PR01469 Bacterial carbamate kinase signature 156 175 1.4E-65 T 10-03-2017 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PRINTS PR01469 Bacterial carbamate kinase signature 39 58 1.4E-65 T 10-03-2017 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 PRINTS PR01469 Bacterial carbamate kinase signature 209 224 1.4E-65 T 10-03-2017 RG49_RS20540 1f71bd628b1094941a35fcc94fe24213 310 TIGRFAM TIGR00746 arcC: carbamate kinase 3 309 3.7E-116 T 10-03-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 SUPERFAMILY SSF46785 27 102 3.66E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 97 1.6E-23 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 Gene3D G3DSA:1.10.10.10 28 95 4.2E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 SMART SM00345 38 97 4.9E-26 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 Pfam PF07702 UTRA domain 118 256 2.1E-32 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 SUPERFAMILY SSF64288 85 264 2.2E-40 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 Gene3D G3DSA:3.40.1410.10 96 264 4.6E-44 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 87 2.9E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 71 2.9E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS17715 34cf5b0c27f5953b2d407c922bf4d778 265 SMART SM00866 118 257 1.0E-29 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 SUPERFAMILY SSF55347 132 319 1.34E-50 T 10-03-2017 RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 SUPERFAMILY SSF51735 5 157 5.4E-43 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 Gene3D G3DSA:3.40.50.720 1 144 3.5E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 PIRSF PIRSF000148 4 337 8.1E-101 T 10-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 117 1.0E-25 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 Gene3D G3DSA:3.30.360.10 145 314 2.5E-51 T 10-03-2017 RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 317 6.0E-42 T 10-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS23485 d7906d1a5ded288755dd1dd0f82ce01a 337 SMART SM00859 6 121 4.4E-32 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS17760 29e426187f3b2d75f464f93349cae78b 108 Pfam PF13806 Rieske-like [2Fe-2S] domain 3 106 6.4E-40 T 10-03-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 RG49_RS17760 29e426187f3b2d75f464f93349cae78b 108 Gene3D G3DSA:2.102.10.10 2 107 2.7E-40 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS17760 29e426187f3b2d75f464f93349cae78b 108 SUPERFAMILY SSF50022 1 107 3.71E-35 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS17760 29e426187f3b2d75f464f93349cae78b 108 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 3 107 3.4E-41 T 10-03-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Pfam PF10385 RNA polymerase beta subunit external 1 domain 591 656 5.3E-28 T 10-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:2.40.50.100 715 792 3.5E-31 T 10-03-2017 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1063 1075 - T 10-03-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Pfam PF04565 RNA polymerase Rpb2, domain 3 513 580 2.0E-30 T 10-03-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 SUPERFAMILY SSF64484 343 939 0.0 T 10-03-2017 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 SUPERFAMILY SSF64484 11 226 0.0 T 10-03-2017 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 SUPERFAMILY SSF64484 1039 1341 0.0 T 10-03-2017 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1342 12.373 T 10-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:2.40.50.150 828 937 2.1E-57 T 10-03-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:2.40.50.150 1045 1059 2.1E-57 T 10-03-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 151 225 2.3E-7 T 10-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 340 454 5.2E-15 T 10-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:3.90.1110.10 153 230 1.3E-65 T 10-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:3.90.1110.10 346 444 1.3E-65 T 10-03-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:2.30.150.10 592 656 6.9E-32 T 10-03-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Pfam PF00562 RNA polymerase Rpb2, domain 6 717 1264 1.2E-160 T 10-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Pfam PF04563 RNA polymerase beta subunit 26 500 2.2E-58 T 10-03-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:3.90.1100.10 20 151 1.1E-147 T 10-03-2017 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:3.90.1100.10 659 713 1.1E-147 T 10-03-2017 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:3.90.1100.10 445 591 1.1E-147 T 10-03-2017 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1339 0.0 T 10-03-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Pfam PF04560 RNA polymerase Rpb2, domain 7 1266 1340 1.9E-27 T 10-03-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:2.40.270.10 793 820 5.2E-90 T 10-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS14155 5a6db54270d33f1e4bfa723559a235e2 1342 Gene3D G3DSA:2.40.270.10 1060 1242 5.2E-90 T 10-03-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 14 182 8.9E-63 T 10-03-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 Gene3D G3DSA:2.30.30.240 106 182 2.8E-29 T 10-03-2017 RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 Gene3D G3DSA:2.40.30.60 6 100 1.3E-36 T 10-03-2017 IPR002676 RimM protein GO:0006364 RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 Pfam PF05239 PRC-barrel domain 104 177 1.7E-9 T 10-03-2017 IPR027275 PRC-barrel domain RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 SUPERFAMILY SSF50447 12 100 4.59E-25 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 13 182 24.865 T 10-03-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 Pfam PF01782 RimM N-terminal domain 16 97 6.6E-27 T 10-03-2017 IPR002676 RimM protein GO:0006364 RG49_RS21990 c07d27980fe1955e3a121e88359a12bc 182 SUPERFAMILY SSF50346 106 182 1.63E-19 T 10-03-2017 IPR011033 PRC-barrel-like RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 Pfam PF13533 Biotin-lipoyl like 47 95 1.5E-20 T 10-03-2017 RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 Pfam PF13437 HlyD family secretion protein 156 239 3.3E-9 T 10-03-2017 RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 Gene3D G3DSA:1.25.40.10 75 153 6.1E-4 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 Gene3D G3DSA:2.40.50.100 47 74 7.9E-19 T 10-03-2017 RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 Gene3D G3DSA:2.40.50.100 154 188 7.9E-19 T 10-03-2017 RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 Hamap MF_01544 p-hydroxybenzoic acid efflux pump subunit AaeA [aaeA]. 1 310 61.799 T 10-03-2017 IPR022871 Para-hydroxybenzoic acid efflux pump, subunit AaeA RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 SUPERFAMILY SSF111369 46 219 9.42E-24 T 10-03-2017 RG49_RS18415 b88754a2ba1b2e13c737ff19d66bfd65 310 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 289 6.0E-34 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 Gene3D G3DSA:3.40.50.720 143 309 2.0E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 SUPERFAMILY SSF50129 299 340 1.69E-5 T 10-03-2017 IPR011032 GroES-like RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 SUPERFAMILY SSF50129 7 146 1.26E-45 T 10-03-2017 IPR011032 GroES-like RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 Gene3D G3DSA:3.90.180.10 4 142 1.6E-58 T 10-03-2017 IPR011032 GroES-like RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 Pfam PF00107 Zinc-binding dehydrogenase 161 297 1.6E-19 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 SMART SM00829 21 339 2.7E-5 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 SUPERFAMILY SSF51735 127 306 1.88E-44 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03145 48779a404907341c0defb4b4b896c2cf 345 Pfam PF16884 N-terminal domain of oxidoreductase 9 115 1.0E-42 T 10-03-2017 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 1.5E-126 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 Gene3D G3DSA:3.40.50.1370 7 144 1.3E-52 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 2.7E-45 T 10-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 SUPERFAMILY SSF53671 4 306 7.73E-101 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.6E-36 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 3.6E-36 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 3.6E-36 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 3.6E-36 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 3.6E-36 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 3.6E-36 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 5.7E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 5.7E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 5.7E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 5.7E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 38.022 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 303 4.2E-29 T 10-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 RG49_RS12665 9d0c600b70c827b4f4c4c35dd66337e1 311 Gene3D G3DSA:3.40.50.1370 145 292 2.5E-56 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.1E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.1E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.1E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 Gene3D G3DSA:1.10.10.10 142 212 4.7E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.8E-20 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 SUPERFAMILY SSF46894 148 212 2.75E-19 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS05460 0dfca4d6363e7ded47f3e127c06516c9 216 SMART SM00421 153 210 1.8E-23 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS18485 39097d4807df3d2ffc8cced7a0aea629 455 Pfam PF03606 C4-dicarboxylate anaerobic carrier 2 454 9.8E-127 T 10-03-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 RG49_RS18485 39097d4807df3d2ffc8cced7a0aea629 455 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 55 444 3.2E-204 T 10-03-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 Pfam PF00106 short chain dehydrogenase 16 204 2.8E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.0E-18 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 5.0E-18 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.0E-18 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.0E-18 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.0E-18 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 Gene3D G3DSA:3.40.50.720 15 264 1.2E-61 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 SUPERFAMILY SSF51735 15 266 1.39E-56 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08605 92659115632610ae29aaf90fb7e32ae9 269 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 195 0.003 T 10-03-2017 RG49_RS00645 d6e3783442cec3367f6157de8b1cd3f3 323 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 12 305 7.0E-110 T 10-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 RG49_RS00645 d6e3783442cec3367f6157de8b1cd3f3 323 Hamap MF_01944 Lipid A biosynthesis myristoyltransferase [lpxM]. 4 310 53.704 T 10-03-2017 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 RG49_RS00645 d6e3783442cec3367f6157de8b1cd3f3 323 TIGRFAM TIGR02208 lipid_A_msbB: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 10 314 7.8E-157 T 10-03-2017 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 RG49_RS00645 d6e3783442cec3367f6157de8b1cd3f3 323 PIRSF PIRSF026649 9 314 2.8E-105 T 10-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 RG49_RS20870 ec3710bdce58c83c1c423dbf2ef76d99 237 Pfam PF03741 Integral membrane protein TerC family 17 203 2.1E-52 T 10-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 RG49_RS24890 9936b0ec9a6daeb31e8bcd6d628a6742 279 Gene3D G3DSA:3.90.550.10 5 241 1.8E-41 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS24890 9936b0ec9a6daeb31e8bcd6d628a6742 279 SUPERFAMILY SSF53448 5 233 3.09E-43 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS24890 9936b0ec9a6daeb31e8bcd6d628a6742 279 Pfam PF00535 Glycosyl transferase family 2 8 154 8.4E-29 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS24890 9936b0ec9a6daeb31e8bcd6d628a6742 279 TIGRFAM TIGR04017 WcaA: colanic acid biosynthesis glycosyltransferase WcaA 1 279 4.8E-195 T 10-03-2017 IPR024009 Colanic acid biosynthesis, glycosyl transferase, WcaA RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 Gene3D G3DSA:1.10.10.10 1 73 6.9E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 Gene3D G3DSA:3.40.190.10 92 196 1.5E-38 T 10-03-2017 RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 Hamap MF_00513 HTH-type transcriptional regulator ArgP [argP]. 1 296 58.997 T 10-03-2017 IPR023490 HTH-type transcriptional regulator ArgP, Gammaproteobacteria RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 SUPERFAMILY SSF46785 4 110 7.37E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 SUPERFAMILY SSF53850 92 289 1.57E-18 T 10-03-2017 RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.5E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.5E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.5E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 9.4E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 Pfam PF03466 LysR substrate binding domain 93 288 1.2E-11 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS20315 83bddd0a987410c35d7911df4a93d36f 297 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 5 293 9.4E-113 T 10-03-2017 IPR017685 HTH-type transcriptional regulator ArgP RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 SUPERFAMILY SSF56925 30 199 7.59E-29 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 187 198 4.6E-29 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 96 119 4.6E-29 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 160 181 4.6E-29 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 49 61 4.6E-29 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 191 199 - T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 Gene3D G3DSA:2.40.160.20 28 199 2.5E-48 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 ProSitePatterns PS00694 Enterobacterial virulence outer membrane protein signature 1. 50 58 - T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS02470 90926c866bcbc6eb43f85c713d999239 199 Pfam PF06316 Enterobacterial Ail/Lom protein 1 199 1.6E-124 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS01980 4ef862735924b745f9c9fcb8677ed8d2 457 Pfam PF13347 MFS/sugar transport protein 12 431 2.3E-93 T 10-03-2017 RG49_RS01980 4ef862735924b745f9c9fcb8677ed8d2 457 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 61 86 - T 10-03-2017 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 RG49_RS01980 4ef862735924b745f9c9fcb8677ed8d2 457 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 444 3.0E-149 T 10-03-2017 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 RG49_RS01980 4ef862735924b745f9c9fcb8677ed8d2 457 Gene3D G3DSA:1.20.1250.20 8 206 2.9E-10 T 10-03-2017 RG49_RS01980 4ef862735924b745f9c9fcb8677ed8d2 457 Gene3D G3DSA:1.20.1250.20 226 433 1.5E-16 T 10-03-2017 RG49_RS01980 4ef862735924b745f9c9fcb8677ed8d2 457 SUPERFAMILY SSF103473 1 433 6.98E-36 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 Pfam PF00672 HAMP domain 156 223 1.9E-13 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 468 555 8.5E-10 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 SUPERFAMILY SSF158472 176 225 2.09E-7 T 10-03-2017 RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 SMART SM00304 174 227 4.3E-12 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 Pfam PF07730 Histidine kinase 361 425 5.8E-19 T 10-03-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 SUPERFAMILY SSF55874 424 555 3.41E-19 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 32 127 6.1E-22 T 10-03-2017 IPR029095 NarX-like, N-terminal RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 Gene3D G3DSA:3.30.565.10 425 558 4.3E-13 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS22825 008e1fdfca189305ad939a3acced1d7f 566 SMART SM00387 465 559 8.6E-15 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00940 e85b00285a9006d7a913031cd385f58f 231 SUPERFAMILY SSF53067 108 217 1.49E-31 T 10-03-2017 RG49_RS00940 e85b00285a9006d7a913031cd385f58f 231 Pfam PF00814 Glycoprotease family 28 131 1.1E-27 T 10-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS00940 e85b00285a9006d7a913031cd385f58f 231 Gene3D G3DSA:3.30.420.40 1 133 1.8E-45 T 10-03-2017 RG49_RS00940 e85b00285a9006d7a913031cd385f58f 231 SUPERFAMILY SSF53067 3 106 2.42E-30 T 10-03-2017 RG49_RS00940 e85b00285a9006d7a913031cd385f58f 231 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 219 7.8E-69 T 10-03-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 178 205 - T 10-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 Pfam PF00107 Zinc-binding dehydrogenase 185 308 3.6E-27 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 142 4.1E-27 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 Gene3D G3DSA:3.40.50.720 180 292 2.6E-26 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 Gene3D G3DSA:3.90.180.10 1 179 5.6E-64 T 10-03-2017 IPR011032 GroES-like RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 SMART SM00829 7 342 7.4E-5 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 SUPERFAMILY SSF51735 151 312 1.11E-43 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09515 b5d80ba7a45d546018efaf0d15f43c1c 349 SUPERFAMILY SSF50129 4 171 6.7E-50 T 10-03-2017 IPR011032 GroES-like RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PIRSF PIRSF000904 1 331 2.2E-120 T 10-03-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PIRSF PIRSF500210 1 330 4.1E-124 T 10-03-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 2 328 41.949 T 10-03-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 SUPERFAMILY SSF56655 2 326 1.13E-111 T 10-03-2017 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 268 280 - T 10-03-2017 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 177 200 1.4E-70 T 10-03-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 27 54 1.4E-70 T 10-03-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 302 327 1.4E-70 T 10-03-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 146 169 1.4E-70 T 10-03-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 203 230 1.4E-70 T 10-03-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 64 90 1.4E-70 T 10-03-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 3 192 2.2E-83 T 10-03-2017 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 Gene3D G3DSA:3.30.540.10 2 192 1.7E-78 T 10-03-2017 RG49_RS12735 6dce545efd3bad72b609138fd3a8b0fe 332 Gene3D G3DSA:3.40.190.80 194 327 3.0E-57 T 10-03-2017 RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 Pfam PF13177 DNA polymerase III, delta subunit 12 164 1.3E-40 T 10-03-2017 RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 13 201 2.0E-59 T 10-03-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 SUPERFAMILY SSF52540 1 207 2.93E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 Gene3D G3DSA:3.40.50.300 9 166 1.5E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 SUPERFAMILY SSF48019 208 328 9.69E-38 T 10-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 208 320 2.9E-37 T 10-03-2017 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 Gene3D G3DSA:1.20.272.10 208 328 4.7E-48 T 10-03-2017 RG49_RS05150 36013ebcd78237ebe4a2d0204c80604b 334 Gene3D G3DSA:1.10.8.10 168 207 4.4E-27 T 10-03-2017 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 SUPERFAMILY SSF48179 283 484 1.26E-64 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 218 230 - T 10-03-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 Gene3D G3DSA:1.10.1040.10 282 485 1.6E-73 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 SUPERFAMILY SSF51735 5 281 7.09E-99 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 Gene3D G3DSA:3.40.50.720 8 281 5.0E-114 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 216 462 2.2E-99 T 10-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 26 188 1.1E-53 T 10-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 PRINTS PR00084 Mannitol dehydrogenase signature 218 231 3.2E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 PRINTS PR00084 Mannitol dehydrogenase signature 27 37 3.2E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 PRINTS PR00084 Mannitol dehydrogenase signature 179 192 3.2E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS24290 5b67be5cc549c99d17623a63946ae4c8 488 PRINTS PR00084 Mannitol dehydrogenase signature 248 263 3.2E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS11735 893ac3fc6cc38127aa1f29fbda66dcc0 164 ProSitePatterns PS00855 Signal peptidases II signature. 104 116 - T 10-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 RG49_RS11735 893ac3fc6cc38127aa1f29fbda66dcc0 164 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 7 162 17.026 T 10-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 RG49_RS11735 893ac3fc6cc38127aa1f29fbda66dcc0 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 53 61 1.5E-19 T 10-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 RG49_RS11735 893ac3fc6cc38127aa1f29fbda66dcc0 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 101 116 1.5E-19 T 10-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 RG49_RS11735 893ac3fc6cc38127aa1f29fbda66dcc0 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 137 153 1.5E-19 T 10-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 RG49_RS11735 893ac3fc6cc38127aa1f29fbda66dcc0 164 Pfam PF01252 Signal peptidase (SPase) II 16 155 4.9E-35 T 10-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 RG49_RS11735 893ac3fc6cc38127aa1f29fbda66dcc0 164 TIGRFAM TIGR00077 lspA: signal peptidase II 1 164 4.2E-61 T 10-03-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 RG49_RS22460 3cd421e54b68db44f5c854e1255dda60 258 Pfam PF14581 SseB protein C-terminal domain 137 243 7.2E-31 T 10-03-2017 IPR027945 SseB protein, C-terminal RG49_RS22460 3cd421e54b68db44f5c854e1255dda60 258 Pfam PF07179 SseB protein N-terminal domain 8 119 1.4E-25 T 10-03-2017 IPR009839 SseB protein N-terminal domain RG49_RS01650 45b221a7f65fe18aefeef1bec5704c51 78 PIRSF PIRSF002855 1 78 1.3E-28 T 10-03-2017 IPR016367 Murein-lipoprotein RG49_RS01650 45b221a7f65fe18aefeef1bec5704c51 78 Pfam PF04728 Lipoprotein leucine-zipper 26 78 7.9E-25 T 10-03-2017 IPR006817 Lipoprotein leucine-zipper GO:0019867 RG49_RS01650 45b221a7f65fe18aefeef1bec5704c51 78 SUPERFAMILY SSF58042 24 74 2.49E-23 T 10-03-2017 RG49_RS01650 45b221a7f65fe18aefeef1bec5704c51 78 Gene3D G3DSA:1.20.5.190 22 73 4.9E-25 T 10-03-2017 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 15 395 1.8E-161 T 10-03-2017 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 Pfam PF03222 Tryptophan/tyrosine permease family 10 402 1.4E-154 T 10-03-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 327 345 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 155 175 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 45 64 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 90 110 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 293 312 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 348 367 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 18 41 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 193 215 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 PRINTS PR00166 Aromatic amino acid permease signature 232 251 2.8E-105 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS18850 ed254db07239fc87bd36c45a42b89b8d 414 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 25 41 - T 10-03-2017 IPR013061 Tryptophan/tryrosine permease, conserved site RG49_RS18685 1d548dd9d8568695e9de75257f23917a 97 Pfam PF13466 STAS domain 14 90 4.2E-18 T 10-03-2017 IPR002645 STAS domain RG49_RS18685 1d548dd9d8568695e9de75257f23917a 97 SUPERFAMILY SSF52091 6 91 2.75E-14 T 10-03-2017 IPR002645 STAS domain RG49_RS18685 1d548dd9d8568695e9de75257f23917a 97 Gene3D G3DSA:3.30.750.24 9 90 2.1E-11 T 10-03-2017 IPR002645 STAS domain RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 SUPERFAMILY SSF52540 195 330 9.11E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 SUPERFAMILY SSF52540 385 676 9.11E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 Pfam PF13361 UvrD-like helicase C-terminal domain 542 659 1.4E-13 T 10-03-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 Gene3D G3DSA:3.40.50.300 395 492 2.6E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 Gene3D G3DSA:3.40.50.300 196 329 2.6E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 Pfam PF12462 DNA helicase IV / RNA helicase N terminal 1 164 1.7E-61 T 10-03-2017 IPR022161 DNA helicase IV, N-terminal domain RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 Pfam PF00580 UvrD/REP helicase N-terminal domain 197 490 8.3E-44 T 10-03-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 RG49_RS05905 20f8059bd87a7e01db92e50ff870e215 684 Gene3D G3DSA:3.40.50.300 500 675 2.7E-23 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 Pfam PF02885 Glycosyl transferase family, helical bundle domain 202 262 1.5E-14 T 10-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 1.3E-12 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 1.3E-12 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 1.3E-12 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 5.4E-5 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 5.4E-5 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 Gene3D G3DSA:1.20.970.10 201 267 3.0E-27 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 Pfam PF00591 Glycosyl transferase family, a/b domain 273 521 8.0E-102 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 SUPERFAMILY SSF52317 3 191 5.5E-44 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 Pfam PF00117 Glutamine amidotransferase class-I 6 186 1.2E-43 T 10-03-2017 IPR017926 Glutamine amidotransferase RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 SUPERFAMILY SSF47648 200 266 4.45E-16 T 10-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 Gene3D G3DSA:3.40.1030.10 273 528 3.3E-97 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 202 530 38.697 T 10-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 204 528 8.3E-130 T 10-03-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00097 Anthranilate synthase component II signature 4 18 3.4E-33 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00097 Anthranilate synthase component II signature 79 90 3.4E-33 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00097 Anthranilate synthase component II signature 124 136 3.4E-33 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00097 Anthranilate synthase component II signature 52 61 3.4E-33 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00097 Anthranilate synthase component II signature 104 112 3.4E-33 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 PRINTS PR00097 Anthranilate synthase component II signature 166 179 3.4E-33 T 10-03-2017 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 186 6.1E-55 T 10-03-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 SUPERFAMILY SSF52418 269 527 1.3E-91 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS04270 7a3c25eec419da59f4a79766bfd0acf3 531 Gene3D G3DSA:3.40.50.880 3 192 1.0E-52 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 Gene3D G3DSA:3.40.50.300 11 254 7.9E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 50 375 1.5E-155 T 10-03-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 SUPERFAMILY SSF52540 19 257 2.73E-87 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 SMART SM00382 44 227 3.6E-18 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 SUPERFAMILY SSF50331 252 375 6.8E-17 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 Pfam PF00005 ABC transporter 36 177 8.7E-37 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06490 7c5efd4eef212cda0e23a9c7e39d3c46 377 Pfam PF08402 TOBE domain 295 375 3.1E-19 T 10-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 Gene3D G3DSA:3.30.565.10 292 443 9.0E-36 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 Gene3D G3DSA:1.10.287.130 223 288 2.5E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 289 2.1E-10 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 SUPERFAMILY SSF55874 292 444 3.67E-35 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 395 7.7E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 7.7E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 7.7E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 438 2.8E-19 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 SMART SM00304 180 232 6.2E-6 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 SMART SM00388 233 293 7.2E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 SUPERFAMILY SSF47384 217 291 5.89E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 SMART SM00387 332 440 2.1E-29 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS17560 c031d0acd4f2e15d990bf4ae754a41c9 450 Pfam PF00672 HAMP domain 162 226 3.2E-12 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS14795 026f422269c4fc077091ff1415d09a3d 467 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 16 451 1.8E-159 T 10-03-2017 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 RG49_RS14795 026f422269c4fc077091ff1415d09a3d 467 Gene3D G3DSA:1.20.1250.20 234 450 1.6E-18 T 10-03-2017 RG49_RS14795 026f422269c4fc077091ff1415d09a3d 467 Gene3D G3DSA:1.20.1250.20 30 204 4.0E-7 T 10-03-2017 RG49_RS14795 026f422269c4fc077091ff1415d09a3d 467 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 67 94 - T 10-03-2017 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 RG49_RS14795 026f422269c4fc077091ff1415d09a3d 467 Pfam PF13347 MFS/sugar transport protein 18 438 6.0E-83 T 10-03-2017 RG49_RS14795 026f422269c4fc077091ff1415d09a3d 467 SUPERFAMILY SSF103473 16 441 1.57E-37 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 187 653 3.2E-265 T 10-03-2017 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 328 640 1.4E-23 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 Gene3D G3DSA:1.10.1060.10 185 330 9.4E-45 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 PRINTS PR00419 Adrenodoxin reductase family signature 471 485 4.4E-38 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 PRINTS PR00419 Adrenodoxin reductase family signature 505 518 4.4E-38 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 PRINTS PR00419 Adrenodoxin reductase family signature 394 404 4.4E-38 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 PRINTS PR00419 Adrenodoxin reductase family signature 352 365 4.4E-38 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 PRINTS PR00419 Adrenodoxin reductase family signature 329 351 4.4E-38 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 Gene3D G3DSA:3.30.70.20 5 174 1.4E-24 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 Gene3D G3DSA:3.40.50.720 573 649 1.8E-10 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 Gene3D G3DSA:3.40.50.720 331 572 5.6E-60 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 Pfam PF13247 4Fe-4S dicluster domain 55 144 3.2E-9 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 SUPERFAMILY SSF54862 196 293 4.6E-43 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 SUPERFAMILY SSF54862 1 161 4.6E-43 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 SUPERFAMILY SSF51971 327 582 5.89E-69 T 10-03-2017 RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS22830 cb522af96a5755bd7714deec2b0a97c6 659 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 205 315 4.3E-37 T 10-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 RG49_RS20400 12a972dd5f0383576d7291fe57e97d52 103 Pfam PF04266 ASCH domain 6 101 1.0E-15 T 10-03-2017 IPR007374 ASCH domain RG49_RS20400 12a972dd5f0383576d7291fe57e97d52 103 Hamap MF_00684 UPF0267 protein YqfB [yqfB]. 2 103 31.999 T 10-03-2017 IPR008314 Uncharacterised conserved protein UCP029143 RG49_RS20400 12a972dd5f0383576d7291fe57e97d52 103 PIRSF PIRSF029143 1 103 2.0E-50 T 10-03-2017 IPR008314 Uncharacterised conserved protein UCP029143 RG49_RS20400 12a972dd5f0383576d7291fe57e97d52 103 Gene3D G3DSA:2.30.130.30 1 102 1.7E-49 T 10-03-2017 RG49_RS20400 12a972dd5f0383576d7291fe57e97d52 103 SUPERFAMILY SSF88697 1 102 3.15E-33 T 10-03-2017 IPR015947 PUA-like domain RG49_RS20400 12a972dd5f0383576d7291fe57e97d52 103 SMART SM01022 6 102 3.8E-26 T 10-03-2017 IPR007374 ASCH domain RG49_RS24750 814d49994ac88a7b688dc76682387d3c 299 Hamap MF_01377 Probable lipid kinase YegS [yegS]. 4 299 48.427 T 10-03-2017 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 RG49_RS24750 814d49994ac88a7b688dc76682387d3c 299 SUPERFAMILY SSF111331 8 297 2.62E-68 T 10-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain RG49_RS24750 814d49994ac88a7b688dc76682387d3c 299 TIGRFAM TIGR03702 lip_kinase_YegS: lipid kinase YegS 7 298 6.0E-142 T 10-03-2017 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 RG49_RS24750 814d49994ac88a7b688dc76682387d3c 299 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 293 3.8E-125 T 10-03-2017 IPR005218 Diacylglycerol/lipid kinase RG49_RS24750 814d49994ac88a7b688dc76682387d3c 299 SMART SM00046 6 132 2.1E-38 T 10-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 RG49_RS24750 814d49994ac88a7b688dc76682387d3c 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 129 1.3E-27 T 10-03-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 632 660 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 Gene3D G3DSA:1.20.1090.10 644 864 1.7E-68 T 10-03-2017 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 SUPERFAMILY SSF53720 6 453 2.62E-85 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 Gene3D G3DSA:3.40.309.10 214 273 3.9E-30 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 Gene3D G3DSA:3.40.309.10 309 404 3.9E-30 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 720 740 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 Gene3D G3DSA:3.40.50.1970 450 643 6.5E-63 T 10-03-2017 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 SUPERFAMILY SSF56796 449 867 4.58E-119 T 10-03-2017 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 Pfam PF00171 Aldehyde dehydrogenase family 5 400 8.4E-29 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 Pfam PF00465 Iron-containing alcohol dehydrogenase 457 850 5.8E-114 T 10-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 Gene3D G3DSA:3.40.605.10 4 206 4.4E-25 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS04395 74428bf03d3c75c944ea0b2eb632701f 891 PIRSF PIRSF000111 1 866 0.0 T 10-03-2017 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 RG49_RS25225 499666be0b545b084ddd6aa5dd112dfa 456 PRINTS PR00173 Glutamate-aspartate symporter signature 300 325 3.0E-6 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS25225 499666be0b545b084ddd6aa5dd112dfa 456 PRINTS PR00173 Glutamate-aspartate symporter signature 260 280 3.0E-6 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS25225 499666be0b545b084ddd6aa5dd112dfa 456 PRINTS PR00173 Glutamate-aspartate symporter signature 423 442 3.0E-6 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS25225 499666be0b545b084ddd6aa5dd112dfa 456 PRINTS PR00173 Glutamate-aspartate symporter signature 219 239 3.0E-6 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS25225 499666be0b545b084ddd6aa5dd112dfa 456 PIRSF PIRSF006304 1 455 4.2E-123 T 10-03-2017 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 RG49_RS25225 499666be0b545b084ddd6aa5dd112dfa 456 Pfam PF03611 PTS system sugar-specific permease component 9 389 4.2E-59 T 10-03-2017 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 RG49_RS13425 871bc0247fd44481964047fde32973d0 111 Pfam PF03831 PhnA domain 44 111 5.2E-35 T 10-03-2017 IPR013988 PhnA protein, C-terminal RG49_RS13425 871bc0247fd44481964047fde32973d0 111 SUPERFAMILY SSF82057 39 110 7.78E-30 T 10-03-2017 RG49_RS13425 871bc0247fd44481964047fde32973d0 111 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 111 7.3E-64 T 10-03-2017 IPR004624 PhnA protein RG49_RS13425 871bc0247fd44481964047fde32973d0 111 Pfam PF08274 PhnA Zinc-Ribbon 2 30 2.0E-15 T 10-03-2017 IPR013987 PhnA protein, N-terminal RG49_RS13425 871bc0247fd44481964047fde32973d0 111 Gene3D G3DSA:2.30.30.40 42 110 3.7E-39 T 10-03-2017 RG49_RS13425 871bc0247fd44481964047fde32973d0 111 SUPERFAMILY SSF57783 1 36 4.76E-14 T 10-03-2017 RG49_RS13425 871bc0247fd44481964047fde32973d0 111 Gene3D G3DSA:2.20.25.10 1 40 1.2E-20 T 10-03-2017 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 1.4E-12 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 1.4E-12 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 Pfam PF08220 DeoR-like helix-turn-helix domain 11 66 6.6E-23 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 SUPERFAMILY SSF46785 9 80 4.45E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 SUPERFAMILY SSF100950 79 239 9.14E-27 T 10-03-2017 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 Gene3D G3DSA:1.10.10.10 3 86 2.5E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 SMART SM00420 11 63 6.9E-25 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 Pfam PF00455 DeoR C terminal sensor domain 79 237 1.8E-49 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 Gene3D G3DSA:3.40.50.1360 87 219 5.1E-14 T 10-03-2017 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS14750 d7a1af2d69db94e8881bbc432c17f655 261 SMART SM01134 77 238 6.6E-62 T 10-03-2017 RG49_RS18640 9e16eff5a04c7b0ce378fdc814bd2127 185 Pfam PF03968 OstA-like protein 37 149 1.6E-32 T 10-03-2017 IPR005653 Organic solvent tolerance-like, N-terminal RG49_RS18640 9e16eff5a04c7b0ce378fdc814bd2127 185 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 7 167 27.239 T 10-03-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 RG49_RS18640 9e16eff5a04c7b0ce378fdc814bd2127 185 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 28 166 9.6E-52 T 10-03-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 RG49_RS18640 9e16eff5a04c7b0ce378fdc814bd2127 185 Gene3D G3DSA:2.60.450.10 29 163 4.9E-43 T 10-03-2017 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 SUPERFAMILY SSF82829 227 312 2.35E-26 T 10-03-2017 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 SMART SM00977 356 427 5.2E-26 T 10-03-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 Pfam PF09179 TilS substrate binding domain 241 308 7.3E-19 T 10-03-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 300 24.07 T 10-03-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 Gene3D G3DSA:3.40.50.620 8 173 7.1E-13 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 356 401 1.6E-16 T 10-03-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 Pfam PF11734 TilS substrate C-terminal domain 356 427 2.9E-26 T 10-03-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 14 196 2.9E-53 T 10-03-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 Pfam PF01171 PP-loop family 14 191 1.2E-61 T 10-03-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 SUPERFAMILY SSF56037 318 426 2.38E-32 T 10-03-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 RG49_RS10875 7e96182a6a7bd0ee063ff97c2ae41716 432 SUPERFAMILY SSF52402 4 226 9.04E-66 T 10-03-2017 RG49_RS09425 0f92e8673924337abf4a0b17bcf6421d 203 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 140 168 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS09425 0f92e8673924337abf4a0b17bcf6421d 203 Pfam PF12464 Maltose acetyltransferase 9 59 6.3E-10 T 10-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 RG49_RS09425 0f92e8673924337abf4a0b17bcf6421d 203 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 96 110 0.23 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS09425 0f92e8673924337abf4a0b17bcf6421d 203 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 8.2E-11 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS09425 0f92e8673924337abf4a0b17bcf6421d 203 SUPERFAMILY SSF51161 6 197 4.44E-56 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS09425 0f92e8673924337abf4a0b17bcf6421d 203 SMART SM01266 6 60 7.0E-15 T 10-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 RG49_RS09425 0f92e8673924337abf4a0b17bcf6421d 203 Gene3D G3DSA:2.160.10.10 6 190 5.1E-62 T 10-03-2017 RG49_RS24675 cd7b18785ef87c8c016d99288a503dd1 272 SMART SM00641 67 178 2.2E-45 T 10-03-2017 IPR018077 Glycoside hydrolase, family 25 subgroup RG49_RS24675 cd7b18785ef87c8c016d99288a503dd1 272 SUPERFAMILY SSF51445 64 267 6.32E-54 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS24675 cd7b18785ef87c8c016d99288a503dd1 272 Gene3D G3DSA:3.20.20.80 65 267 1.2E-66 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS24675 cd7b18785ef87c8c016d99288a503dd1 272 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 71 109 - T 10-03-2017 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 RG49_RS24675 cd7b18785ef87c8c016d99288a503dd1 272 Pfam PF01183 Glycosyl hydrolases family 25 70 245 1.4E-54 T 10-03-2017 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 6.2E-23 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 6.2E-23 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 6.2E-23 T 10-03-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 SUPERFAMILY SSF54909 74 157 4.16E-22 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 Pfam PF01037 Lrp/AsnC ligand binding domain 78 152 1.1E-24 T 10-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 10-03-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 SUPERFAMILY SSF46785 12 70 4.01E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 2.7E-21 T 10-03-2017 RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 SMART SM00344 12 121 3.5E-55 T 10-03-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 Gene3D G3DSA:3.30.70.920 65 161 2.3E-33 T 10-03-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain RG49_RS06290 60feb0dfbdfa96c198c39b45781a4348 164 Gene3D G3DSA:1.10.10.10 13 64 1.0E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13085 ddc1d6bb3e5a128d2b03981dca1be080 379 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 14 348 4.9E-154 T 10-03-2017 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 RG49_RS13085 ddc1d6bb3e5a128d2b03981dca1be080 379 Pfam PF13484 4Fe-4S double cluster binding domain 193 256 3.7E-19 T 10-03-2017 RG49_RS13085 ddc1d6bb3e5a128d2b03981dca1be080 379 Pfam PF08331 Domain of unknown function (DUF1730) 62 140 1.2E-23 T 10-03-2017 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 RG49_RS13085 ddc1d6bb3e5a128d2b03981dca1be080 379 Gene3D G3DSA:3.30.70.20 190 258 4.3E-6 T 10-03-2017 RG49_RS13085 ddc1d6bb3e5a128d2b03981dca1be080 379 SUPERFAMILY SSF46548 139 256 5.23E-19 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS13085 ddc1d6bb3e5a128d2b03981dca1be080 379 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 7 315 51.509 T 10-03-2017 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 RG49_RS13085 ddc1d6bb3e5a128d2b03981dca1be080 379 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 193 204 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 TIGRFAM TIGR03244 arg_catab_AstA: arginine N-succinyltransferase 3 337 2.7E-168 T 10-03-2017 IPR017650 Arginine N-succinyltransferase GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 335 1.8E-146 T 10-03-2017 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 SUPERFAMILY SSF55729 1 337 3.82E-135 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 Gene3D G3DSA:3.40.630.30 218 246 1.4E-8 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 Gene3D G3DSA:3.40.630.30 1 150 1.4E-8 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 Gene3D G3DSA:2.40.40.20 273 337 2.5E-12 T 10-03-2017 RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 3 337 1.5E-155 T 10-03-2017 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 RG49_RS01260 2bbf2e847e82d59300e9b6b74fad999d 344 Hamap MF_01171 Arginine N-succinyltransferase [astA]. 1 344 70.659 T 10-03-2017 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 RG49_RS01605 e2c9322164568340796281692e9f16a2 136 Pfam PF03061 Thioesterase superfamily 50 127 9.6E-17 T 10-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 RG49_RS01605 e2c9322164568340796281692e9f16a2 136 Gene3D G3DSA:3.10.129.10 1 136 8.1E-52 T 10-03-2017 IPR029069 HotDog domain RG49_RS01605 e2c9322164568340796281692e9f16a2 136 SUPERFAMILY SSF54637 1 133 1.49E-29 T 10-03-2017 IPR029069 HotDog domain RG49_RS01605 e2c9322164568340796281692e9f16a2 136 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 134 1.1E-47 T 10-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 RG49_RS01605 e2c9322164568340796281692e9f16a2 136 Hamap MF_01936 1,4-dihydroxy-2-naphthoyl-CoA hydrolase [menI]. 1 136 48.921 T 10-03-2017 IPR030863 1,4-dihydroxy-2-naphthoyl-CoA hydrolase, MenI GO:0009234|GO:0061522 KEGG: 00130+3.1.2.28|MetaCyc: PWY-5837 RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 74 1.9E-12 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 SUPERFAMILY SSF52833 1 78 1.1E-19 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 SUPERFAMILY SSF47616 76 215 7.14E-49 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 TIGRFAM TIGR02182 GRXB: glutaredoxin, GrxB family 2 210 7.2E-104 T 10-03-2017 IPR011901 Glutaredoxin, GrxB GO:0009055|GO:0015035 RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 Pfam PF04399 Glutaredoxin 2, C terminal domain 86 214 4.6E-49 T 10-03-2017 IPR007494 Glutaredoxin 2, C-terminal RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 Gene3D G3DSA:1.20.1050.10 90 215 2.3E-50 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 Gene3D G3DSA:3.40.30.10 8 83 3.3E-31 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS05325 c7aa224648b2c0d69c21c2f6fed97c1d 215 ProSitePatterns PS00195 Glutaredoxin active site. 3 18 - T 10-03-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 SUPERFAMILY SSF52210 239 385 9.81E-53 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 10-03-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 Gene3D G3DSA:3.30.1490.20 22 95 2.0E-35 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 Gene3D G3DSA:3.30.470.20 96 239 4.7E-57 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.133 T 10-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 SUPERFAMILY SSF56059 1 238 2.65E-81 T 10-03-2017 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 PIRSF PIRSF001554 1 388 6.3E-154 T 10-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 Pfam PF08442 ATP-grasp domain 2 203 5.4E-83 T 10-03-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.9E-183 T 10-03-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 Pfam PF00549 CoA-ligase 262 382 2.1E-24 T 10-03-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS07415 d3e359441fbb6d15ad5d4ade4c910750 388 Gene3D G3DSA:3.40.50.261 240 383 3.4E-64 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS18145 042540b999f41ce72ccf06399fb32492 72 Pfam PF03889 Domain of unknown function 9 45 9.3E-23 T 10-03-2017 IPR005589 Protein of unknown function DUF331 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 10-03-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 3.3E-19 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 3.3E-19 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 3.3E-19 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 SUPERFAMILY SSF47729 1 91 6.92E-30 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 Gene3D G3DSA:4.10.520.10 1 91 2.4E-34 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.6E-30 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 SMART SM00411 1 91 1.6E-43 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 30.437 T 10-03-2017 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 RG49_RS06175 2e51831bd5af44198685ea29ced2c512 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 6.3E-54 T 10-03-2017 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 SUPERFAMILY SSF53067 187 382 5.12E-69 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 SUPERFAMILY SSF100934 507 602 6.54E-31 T 10-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:3.30.420.40 319 361 8.5E-34 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:3.30.420.40 197 229 8.5E-34 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 634 37.27 T 10-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:3.30.420.40 4 52 1.2E-63 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:3.30.420.40 119 196 1.2E-63 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:3.30.30.30 53 108 1.7E-28 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 6.3E-294 T 10-03-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 10-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 334 350 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 469 485 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 138 158 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 198 208 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 31 43 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 54 62 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 3 16 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 388 407 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 PRINTS PR00301 70kDa heat shock protein signature 365 385 6.0E-81 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 10-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 SUPERFAMILY SSF100920 384 539 1.29E-61 T 10-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 SUPERFAMILY SSF53067 4 183 3.56E-66 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 10-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:1.20.1270.10 532 601 1.1E-28 T 10-03-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:3.90.640.10 230 315 5.3E-32 T 10-03-2017 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Gene3D G3DSA:2.60.34.10 390 531 1.0E-70 T 10-03-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 RG49_RS11820 0d39280bf6256e4ebfb5b40449c56b29 638 Pfam PF00012 Hsp70 protein 4 602 2.6E-270 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS04015 e9921b39277c0b42ae747f7a86edb6b4 74 Pfam PF06667 Phage shock protein B 3 73 1.6E-32 T 10-03-2017 IPR009554 Phage shock protein B GO:0006355|GO:0009271 RG49_RS04015 e9921b39277c0b42ae747f7a86edb6b4 74 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 1 74 1.1E-33 T 10-03-2017 IPR009554 Phage shock protein B GO:0006355|GO:0009271 RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1172 1249 1.0E-23 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 Pfam PF03527 RHS protein 1145 1182 2.7E-16 T 10-03-2017 IPR001826 RHS protein RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 PRINTS PR00394 RHS protein signature 1170 1185 1.1E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 PRINTS PR00394 RHS protein signature 1139 1159 1.1E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 PRINTS PR00394 RHS protein signature 1194 1214 1.1E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 PRINTS PR00394 RHS protein signature 1217 1236 1.1E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 PRINTS PR00394 RHS protein signature 1101 1120 1.1E-47 T 10-03-2017 IPR001826 RHS protein RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 677 3.0E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 468 508 4.8E-7 T 10-03-2017 IPR006530 YD repeat RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 596 627 7.8E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 575 614 1.3E-9 T 10-03-2017 IPR006530 YD repeat RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 Pfam PF05593 RHS Repeat 617 652 8.2E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS25390 3eb623819ec89dd2d7c95c3e803b2ffb 1396 Pfam PF05593 RHS Repeat 575 611 9.3E-9 T 10-03-2017 IPR031325 RHS repeat RG49_RS19635 3fe4a5416a2405f9dfe93ad88db2e9ef 160 Gene3D G3DSA:3.20.80.10 7 159 5.3E-43 T 10-03-2017 IPR011256 Regulatory factor, effector binding domain RG49_RS19635 3fe4a5416a2405f9dfe93ad88db2e9ef 160 Pfam PF06445 GyrI-like small molecule binding domain 7 159 4.3E-31 T 10-03-2017 IPR029442 GyrI-like small molecule binding domain RG49_RS19635 3fe4a5416a2405f9dfe93ad88db2e9ef 160 SMART SM00871 6 160 3.7E-31 T 10-03-2017 IPR010499 Bacterial transcription activator, effector binding RG49_RS19635 3fe4a5416a2405f9dfe93ad88db2e9ef 160 SUPERFAMILY SSF55136 7 159 2.27E-31 T 10-03-2017 IPR011256 Regulatory factor, effector binding domain RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 PIRSF PIRSF001220 1 334 9.6E-98 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 Gene3D G3DSA:3.40.50.1170 5 197 4.0E-79 T 10-03-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 3 335 8.0E-144 T 10-03-2017 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 Pfam PF00710 Asparaginase, N-terminal 6 188 1.1E-66 T 10-03-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 SUPERFAMILY SSF53774 3 335 3.27E-114 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 SMART SM00870 5 323 2.5E-142 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 8 16 - T 10-03-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 Gene3D G3DSA:3.40.50.40 211 336 2.6E-51 T 10-03-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 84 94 - T 10-03-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 PIRSF PIRSF500176 2 332 3.5E-120 T 10-03-2017 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 4.1E-17 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 PRINTS PR00139 Asparaginase/glutaminase family signature 83 101 4.1E-17 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS01150 76ea8c24e84257c4e0ecb25205e7e2fa 338 PRINTS PR00139 Asparaginase/glutaminase family signature 260 278 4.1E-17 T 10-03-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 RG49_RS16970 a250519128938876abacc9363e2705cc 385 Gene3D G3DSA:2.40.50.100 61 94 5.6E-22 T 10-03-2017 RG49_RS16970 a250519128938876abacc9363e2705cc 385 Gene3D G3DSA:2.40.50.100 169 203 5.6E-22 T 10-03-2017 RG49_RS16970 a250519128938876abacc9363e2705cc 385 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 369 3.2E-80 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS16970 a250519128938876abacc9363e2705cc 385 SUPERFAMILY SSF111369 50 296 5.23E-81 T 10-03-2017 RG49_RS16970 a250519128938876abacc9363e2705cc 385 Pfam PF00529 HlyD membrane-fusion protein of T1SS 35 356 1.3E-9 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS16970 a250519128938876abacc9363e2705cc 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 289 2.8E-17 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS04810 1794c88c6f536fe1353ee70f3d6bf1f5 74 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1 74 1.4E-11 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS04810 1794c88c6f536fe1353ee70f3d6bf1f5 74 SUPERFAMILY SSF103515 2 74 1.83E-6 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS04810 1794c88c6f536fe1353ee70f3d6bf1f5 74 Gene3D G3DSA:2.40.128.130 1 74 1.6E-11 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 10-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 Pfam PF10415 Fumarase C C-terminus 411 464 4.1E-17 T 10-03-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 SUPERFAMILY SSF48557 2 458 4.71E-147 T 10-03-2017 IPR008948 L-Aspartase-like GO:0003824 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 Gene3D G3DSA:1.10.275.10 4 142 3.0E-57 T 10-03-2017 IPR024083 Fumarase/histidase, N-terminal RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 Gene3D G3DSA:1.10.40.30 411 462 5.9E-19 T 10-03-2017 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 6 474 2.0E-276 T 10-03-2017 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 Gene3D G3DSA:1.20.200.10 143 405 6.8E-91 T 10-03-2017 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 1.4E-5 T 10-03-2017 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 PRINTS PR00145 Argininosuccinate lyase family signature 137 159 1.4E-5 T 10-03-2017 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 1.4E-5 T 10-03-2017 RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 Pfam PF00206 Lyase 13 345 1.3E-117 T 10-03-2017 IPR022761 Fumarate lyase, N-terminal RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 4.8E-28 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 4.8E-28 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 4.8E-28 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS13235 450d855a66b57220e455c3824dd9226b 478 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 4.8E-28 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS16205 2931cc9d77f9b98049ada7f809299e11 406 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 371 2.0E-73 T 10-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 RG49_RS16205 2931cc9d77f9b98049ada7f809299e11 406 Gene3D G3DSA:3.40.50.10300 184 404 4.4E-88 T 10-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 RG49_RS16205 2931cc9d77f9b98049ada7f809299e11 406 Gene3D G3DSA:3.40.50.1950 3 182 1.1E-62 T 10-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 RG49_RS16205 2931cc9d77f9b98049ada7f809299e11 406 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 397 6.8E-166 T 10-03-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 RG49_RS16205 2931cc9d77f9b98049ada7f809299e11 406 SUPERFAMILY SSF102645 184 401 7.19E-80 T 10-03-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 RG49_RS16205 2931cc9d77f9b98049ada7f809299e11 406 Pfam PF02441 Flavoprotein 6 133 1.9E-30 T 10-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 RG49_RS16205 2931cc9d77f9b98049ada7f809299e11 406 SUPERFAMILY SSF52507 3 180 4.84E-58 T 10-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 RG49_RS21470 09976bfbdc0baa4993e58190178f1500 307 Pfam PF00146 NADH dehydrogenase 9 302 8.0E-49 T 10-03-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21470 09976bfbdc0baa4993e58190178f1500 307 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 38 53 - T 10-03-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21470 09976bfbdc0baa4993e58190178f1500 307 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 194 207 - T 10-03-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS15310 850143d49315e8891aad60bd107000ef 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 10-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 RG49_RS15310 850143d49315e8891aad60bd107000ef 109 Gene3D G3DSA:3.40.30.10 2 108 3.5E-43 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS15310 850143d49315e8891aad60bd107000ef 109 PIRSF PIRSF000077 2 108 4.8E-45 T 10-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 RG49_RS15310 850143d49315e8891aad60bd107000ef 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 2.1E-39 T 10-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 RG49_RS15310 850143d49315e8891aad60bd107000ef 109 PRINTS PR00421 Thioredoxin family signature 24 32 3.8E-10 T 10-03-2017 RG49_RS15310 850143d49315e8891aad60bd107000ef 109 PRINTS PR00421 Thioredoxin family signature 72 83 3.8E-10 T 10-03-2017 RG49_RS15310 850143d49315e8891aad60bd107000ef 109 PRINTS PR00421 Thioredoxin family signature 32 41 3.8E-10 T 10-03-2017 RG49_RS15310 850143d49315e8891aad60bd107000ef 109 SUPERFAMILY SSF52833 2 108 1.04E-41 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS15310 850143d49315e8891aad60bd107000ef 109 Pfam PF00085 Thioredoxin 5 106 2.0E-34 T 10-03-2017 IPR013766 Thioredoxin domain GO:0045454 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 Pfam PF02910 Fumarate reductase flavoprotein C-term 460 588 2.0E-35 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 5.5E-5 T 10-03-2017 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 390 5.5E-5 T 10-03-2017 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 588 5.2E-242 T 10-03-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 SUPERFAMILY SSF46977 452 588 2.88E-46 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 SUPERFAMILY SSF51905 4 259 1.97E-75 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 SUPERFAMILY SSF51905 359 440 1.97E-75 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 10-03-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 6 588 1.8E-278 T 10-03-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 PIRSF PIRSF000171 1 579 4.0E-47 T 10-03-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 Gene3D G3DSA:1.20.58.100 433 547 6.0E-38 T 10-03-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 Gene3D G3DSA:3.90.700.10 243 349 1.5E-40 T 10-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 SUPERFAMILY SSF56425 236 356 4.64E-42 T 10-03-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 Gene3D G3DSA:4.10.80.40 548 588 2.7E-21 T 10-03-2017 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 Pfam PF00890 FAD binding domain 9 405 2.5E-118 T 10-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 Gene3D G3DSA:3.50.50.60 351 425 2.5E-119 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS07440 d58a08a8499799efa72d9df42f21ed0f 588 Gene3D G3DSA:3.50.50.60 6 242 2.5E-119 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 Gene3D G3DSA:3.40.50.620 340 461 6.5E-36 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 474 43.584 T 10-03-2017 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 SUPERFAMILY SSF53613 12 309 5.14E-60 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 Gene3D G3DSA:3.40.1190.20 13 313 1.2E-69 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 Pfam PF00294 pfkB family carbohydrate kinase 12 305 4.9E-60 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 5 312 3.0E-130 T 10-03-2017 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 332 473 2.1E-64 T 10-03-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 Pfam PF01467 Cytidylyltransferase-like 345 469 3.5E-15 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 342 408 5.4E-18 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS19485 8c74d913e2fc37c6a6d92d97771b0e31 477 SUPERFAMILY SSF52374 340 471 7.32E-22 T 10-03-2017 RG49_RS14780 bf02ea8d55a59f822c4d2a6371df9bd2 291 Pfam PF01925 Sulfite exporter TauE/SafE 23 248 4.9E-32 T 10-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 RG49_RS24210 9be2c96a399f8a2736b461b69d22d4db 335 Pfam PF04245 37-kD nucleoid-associated bacterial protein 10 324 2.5E-99 T 10-03-2017 IPR007358 Nucleoid-associated protein NdpA GO:0009295 RG49_RS24210 9be2c96a399f8a2736b461b69d22d4db 335 Hamap MF_00730 Nucleoid-associated protein YejK [yejK]. 3 330 47.365 T 10-03-2017 IPR007358 Nucleoid-associated protein NdpA GO:0009295 RG49_RS18380 388c1f1c8f32ff750b138a39fd86c3d7 197 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 182 5.4E-76 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS18380 388c1f1c8f32ff750b138a39fd86c3d7 197 Gene3D G3DSA:3.90.950.10 2 185 7.3E-72 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS18380 388c1f1c8f32ff750b138a39fd86c3d7 197 Hamap MF_00528 Septum formation protein Maf [maf]. 3 189 32.909 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS18380 388c1f1c8f32ff750b138a39fd86c3d7 197 SUPERFAMILY SSF52972 2 184 7.19E-64 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS18380 388c1f1c8f32ff750b138a39fd86c3d7 197 Pfam PF02545 Maf-like protein 4 184 1.9E-59 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS18380 388c1f1c8f32ff750b138a39fd86c3d7 197 PIRSF PIRSF006305 1 191 1.4E-57 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 SUPERFAMILY SSF51735 161 333 9.87E-44 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 6.4E-27 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 1.4E-224 T 10-03-2017 IPR014183 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|Reactome: R-HSA-71384 RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 Pfam PF00107 Zinc-binding dehydrogenase 197 329 8.9E-21 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 SMART SM00829 12 367 5.2E-4 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 SUPERFAMILY SSF50129 1 185 3.5E-71 T 10-03-2017 IPR011032 GroES-like RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 Gene3D G3DSA:3.40.50.720 191 309 2.4E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 SUPERFAMILY SSF50129 318 369 4.71E-12 T 10-03-2017 IPR011032 GroES-like RG49_RS09340 c88d52d64aa9f530252391471499d7e9 369 Gene3D G3DSA:3.90.180.10 2 190 2.3E-69 T 10-03-2017 IPR011032 GroES-like RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SMART SM00448 682 794 1.4E-15 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Gene3D G3DSA:1.20.120.160 818 907 4.4E-17 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 TIGRFAM TIGR02956 TMAO_torS: TMAO reductase sytem sensor TorS 5 806 5.2E-271 T 10-03-2017 IPR014302 Signal transduction histidine kinase, TMAO sensor TorS GO:0000155|GO:0000160|GO:0004673|GO:0016021 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SUPERFAMILY SSF47384 426 508 6.67E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Pfam PF00672 HAMP domain 334 404 9.0E-8 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Gene3D G3DSA:3.40.50.2300 681 817 3.5E-23 T 10-03-2017 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SUPERFAMILY SSF55874 497 663 8.91E-42 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Pfam PF00072 Response regulator receiver domain 685 792 7.0E-14 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Pfam PF00512 His Kinase A (phospho-acceptor) domain 443 508 1.3E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 611 621 1.6E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 648 661 1.6E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 593 607 1.6E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 642 1.6E-14 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SMART SM00073 818 914 6.4E-24 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 PIRSF PIRSF036437 1 914 0.0 T 10-03-2017 IPR014302 Signal transduction histidine kinase, TMAO sensor TorS GO:0000155|GO:0000160|GO:0004673|GO:0016021 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Gene3D G3DSA:3.30.565.10 513 666 3.0E-44 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SMART SM00388 443 508 4.0E-20 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SMART SM00304 354 407 4.8E-5 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SMART SM00387 557 664 3.9E-37 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SUPERFAMILY SSF52172 680 808 2.42E-23 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 SUPERFAMILY SSF47226 804 908 1.7E-18 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 557 663 2.9E-25 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Gene3D G3DSA:1.10.287.130 436 503 8.4E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS05735 89b4e53b6f50cd8cb5ce68e73894c0de 914 Pfam PF01627 Hpt domain 827 905 6.2E-11 T 10-03-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 RG49_RS12930 5ffd296bca997aa129609d699eec071b 216 Hamap MF_01267 3-keto-L-gulonate-6-phosphate decarboxylase UlaD [ulaD]. 1 216 69.516 T 10-03-2017 IPR023942 3-keto-L-gulonate-6-phosphate decarboxylase, UlaD GO:0000287|GO:0019854|GO:0033982 KEGG: 00040+4.1.1.85|KEGG: 00053+4.1.1.85|MetaCyc: PWY-6961 RG49_RS12930 5ffd296bca997aa129609d699eec071b 216 SMART SM00934 5 207 5.5E-35 T 10-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12930 5ffd296bca997aa129609d699eec071b 216 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 206 4.4E-31 T 10-03-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS12930 5ffd296bca997aa129609d699eec071b 216 SUPERFAMILY SSF51366 2 215 7.21E-41 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS12930 5ffd296bca997aa129609d699eec071b 216 Gene3D G3DSA:3.20.20.70 2 215 3.1E-81 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS23615 686577aac277f737d875fe198ea6460a 164 PIRSF PIRSF006272 1 164 2.9E-80 T 10-03-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU RG49_RS23615 686577aac277f737d875fe198ea6460a 164 Hamap MF_00762 UPF0304 protein YfbU [yfbU]. 1 164 40.884 T 10-03-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU RG49_RS23615 686577aac277f737d875fe198ea6460a 164 Gene3D G3DSA:1.10.3190.10 53 164 1.4E-51 T 10-03-2017 IPR023146 YfbU, alpha-helical bundle domain RG49_RS23615 686577aac277f737d875fe198ea6460a 164 ProDom PD035118 UPF0304 YFBU PLASMID YPO2563/Y1624/YP2374 YBFU PM1500 OXYGEN ECA3037 VV12093 PROTEIN 1 164 1.0E-95 T 10-03-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU RG49_RS23615 686577aac277f737d875fe198ea6460a 164 Pfam PF03887 YfbU domain 1 164 2.9E-69 T 10-03-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU RG49_RS23615 686577aac277f737d875fe198ea6460a 164 Gene3D G3DSA:1.10.287.680 1 52 2.4E-31 T 10-03-2017 IPR023145 YfbU, helix-hairpin domain RG49_RS23615 686577aac277f737d875fe198ea6460a 164 SUPERFAMILY SSF116960 1 164 1.1E-70 T 10-03-2017 RG49_RS14100 c11af8cb9a5dedf563e02e64908817c1 354 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 10-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS14100 c11af8cb9a5dedf563e02e64908817c1 354 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 347 1.0E-142 T 10-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS14100 c11af8cb9a5dedf563e02e64908817c1 354 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 347 2.4E-137 T 10-03-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS14100 c11af8cb9a5dedf563e02e64908817c1 354 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 349 50.745 T 10-03-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS14100 c11af8cb9a5dedf563e02e64908817c1 354 SUPERFAMILY SSF51726 1 352 7.98E-123 T 10-03-2017 RG49_RS14100 c11af8cb9a5dedf563e02e64908817c1 354 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 10-03-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS14100 c11af8cb9a5dedf563e02e64908817c1 354 Gene3D G3DSA:3.20.20.210 2 352 2.4E-158 T 10-03-2017 RG49_RS16955 2d0584b36a0ac81361ae76d80a82fcf4 242 Gene3D G3DSA:1.10.10.60 189 235 1.7E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16955 2d0584b36a0ac81361ae76d80a82fcf4 242 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 188 230 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS16955 2d0584b36a0ac81361ae76d80a82fcf4 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 203 218 9.3E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS16955 2d0584b36a0ac81361ae76d80a82fcf4 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 218 234 9.3E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS16955 2d0584b36a0ac81361ae76d80a82fcf4 242 SUPERFAMILY SSF46689 188 236 4.93E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16955 2d0584b36a0ac81361ae76d80a82fcf4 242 SMART SM00342 152 234 1.6E-26 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS16955 2d0584b36a0ac81361ae76d80a82fcf4 242 Pfam PF12833 Helix-turn-helix domain 158 235 2.8E-12 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS08750 6d41a83e06643bdacab599c5dd5ed77c 183 Pfam PF00156 Phosphoribosyl transferase domain 31 156 2.1E-15 T 10-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 RG49_RS08750 6d41a83e06643bdacab599c5dd5ed77c 183 Gene3D G3DSA:3.40.50.2020 7 179 8.4E-71 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS08750 6d41a83e06643bdacab599c5dd5ed77c 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 180 39.352 T 10-03-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 RG49_RS08750 6d41a83e06643bdacab599c5dd5ed77c 183 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 11 178 2.8E-75 T 10-03-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 RG49_RS08750 6d41a83e06643bdacab599c5dd5ed77c 183 SUPERFAMILY SSF53271 12 180 7.1E-53 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 Gene3D G3DSA:3.90.190.20 300 433 4.3E-45 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 SUPERFAMILY SSF53244 299 437 8.93E-55 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 373 1.8E-10 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 437 35.226 T 10-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 SUPERFAMILY SSF51984 3 94 3.14E-25 T 10-03-2017 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 SUPERFAMILY SSF53623 95 297 4.84E-58 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 Gene3D G3DSA:3.40.50.720 3 92 1.6E-27 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 Pfam PF08245 Mur ligase middle domain 110 280 4.8E-29 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 435 3.1E-131 T 10-03-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11415 8854d7953ec4e73de0c110b3373df75d 438 Gene3D G3DSA:3.40.1190.10 94 299 9.3E-69 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 Gene3D G3DSA:3.30.390.50 165 252 2.4E-12 T 10-03-2017 RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 Gene3D G3DSA:3.30.465.10 53 138 1.7E-12 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 167 248 6.1E-5 T 10-03-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 SUPERFAMILY SSF56176 4 154 8.18E-24 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 SMART SM01092 161 251 3.5E-11 T 10-03-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 TIGRFAM TIGR03312 Se_sel_red_FAD: probable selenate reductase, FAD-binding subunit 2 258 3.8E-148 T 10-03-2017 IPR017698 Probable selenate reductase, FAD-binding subunit RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 146 1.3E-19 T 10-03-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 RG49_RS20505 be97866f61c7dc08f7edcd699c4015ca 259 SUPERFAMILY SSF55447 164 252 2.22E-13 T 10-03-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal RG49_RS23925 953a383e057175bf1bc9183454c0f221 84 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 10-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 RG49_RS23925 953a383e057175bf1bc9183454c0f221 84 Gene3D G3DSA:3.10.20.30 2 83 2.3E-19 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS23925 953a383e057175bf1bc9183454c0f221 84 SUPERFAMILY SSF54292 3 83 1.84E-21 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS23925 953a383e057175bf1bc9183454c0f221 84 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 77 1.3E-10 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS18855 6547a4edb113747cab8e6e6e19a4fd73 335 Gene3D G3DSA:3.20.20.30 2 327 4.2E-90 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS18855 6547a4edb113747cab8e6e6e19a4fd73 335 Pfam PF00296 Luciferase-like monooxygenase 20 300 1.3E-34 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS18855 6547a4edb113747cab8e6e6e19a4fd73 335 SUPERFAMILY SSF51679 7 328 1.07E-86 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS18855 6547a4edb113747cab8e6e6e19a4fd73 335 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 327 7.1E-134 T 10-03-2017 IPR019949 Luciferase family oxidoreductase, group 1 RG49_RS02620 3bef48a53f067e42ea93ae0d0de36bd6 483 Hamap MF_00670 Altronate oxidoreductase [uxaB]. 1 483 57.891 T 10-03-2017 IPR023668 Altronate oxidoreductase GO:0009026|GO:0055114 KEGG: 00040+1.1.1.58 RG49_RS02620 3bef48a53f067e42ea93ae0d0de36bd6 483 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 203 458 4.5E-83 T 10-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 RG49_RS02620 3bef48a53f067e42ea93ae0d0de36bd6 483 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 17 172 2.1E-41 T 10-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 RG49_RS02620 3bef48a53f067e42ea93ae0d0de36bd6 483 SUPERFAMILY SSF51735 2 264 2.87E-67 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02620 3bef48a53f067e42ea93ae0d0de36bd6 483 SUPERFAMILY SSF48179 273 482 7.48E-53 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS02620 3bef48a53f067e42ea93ae0d0de36bd6 483 Gene3D G3DSA:1.10.1040.10 272 482 2.4E-68 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS02620 3bef48a53f067e42ea93ae0d0de36bd6 483 Gene3D G3DSA:3.40.50.720 3 263 2.1E-70 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS00725 116893c36704c83981ded246e9970f2d 220 Gene3D G3DSA:3.30.420.10 4 152 4.3E-38 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS00725 116893c36704c83981ded246e9970f2d 220 Pfam PF00929 Exonuclease 4 147 1.7E-14 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS00725 116893c36704c83981ded246e9970f2d 220 SMART SM00479 1 156 7.0E-40 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS00725 116893c36704c83981ded246e9970f2d 220 SUPERFAMILY SSF53098 4 182 2.08E-34 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS05695 3adb98ac07f99ea95af8e212fbaa7297 413 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 31 45 - T 10-03-2017 IPR033379 Histidine acid phosphatase active site RG49_RS05695 3adb98ac07f99ea95af8e212fbaa7297 413 SUPERFAMILY SSF53254 24 411 6.73E-78 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05695 3adb98ac07f99ea95af8e212fbaa7297 413 Pfam PF00328 Histidine phosphatase superfamily (branch 2) 31 363 2.0E-15 T 10-03-2017 IPR000560 Histidine phosphatase superfamily, clade-2 GO:0003993 RG49_RS05695 3adb98ac07f99ea95af8e212fbaa7297 413 Gene3D G3DSA:3.40.50.1240 142 274 2.4E-69 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05695 3adb98ac07f99ea95af8e212fbaa7297 413 Gene3D G3DSA:3.40.50.1240 26 141 2.0E-84 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05695 3adb98ac07f99ea95af8e212fbaa7297 413 Gene3D G3DSA:3.40.50.1240 276 412 2.0E-84 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05695 3adb98ac07f99ea95af8e212fbaa7297 413 ProSitePatterns PS00778 Histidine acid phosphatases active site signature. 305 321 - T 10-03-2017 IPR033379 Histidine acid phosphatase active site RG49_RS02910 3376089565e5e6932e81ddace09e7991 328 SMART SM00382 34 234 3.5E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS02910 3376089565e5e6932e81ddace09e7991 328 Pfam PF00005 ABC transporter 25 184 3.3E-27 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS02910 3376089565e5e6932e81ddace09e7991 328 Gene3D G3DSA:3.40.50.300 4 258 7.0E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02910 3376089565e5e6932e81ddace09e7991 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 6.8E-22 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS02910 3376089565e5e6932e81ddace09e7991 328 SUPERFAMILY SSF52540 3 261 5.33E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02910 3376089565e5e6932e81ddace09e7991 328 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS02910 3376089565e5e6932e81ddace09e7991 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 2.9E-17 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS14900 45589e0d6140d039b9ea5e4c18478b35 89 Pfam PF06288 Protein of unknown function (DUF1040) 1 86 3.1E-46 T 10-03-2017 IPR009383 Protein of unknown function DUF1040 RG49_RS14900 45589e0d6140d039b9ea5e4c18478b35 89 ProDom PD029038 YIHD CYTOPLASMIC ENZYME Y3814 GLYCOGEN YPO0013A HI0845 DIRECT ORF1 UNCHARACTERIZED 1 87 1.0E-44 T 10-03-2017 IPR009383 Protein of unknown function DUF1040 RG49_RS22150 d4fa617428ea4cdbfd79a0a6ff7af32a 308 Pfam PF03466 LysR substrate binding domain 102 304 3.2E-42 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS22150 d4fa617428ea4cdbfd79a0a6ff7af32a 308 Gene3D G3DSA:1.10.10.10 16 94 1.5E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22150 d4fa617428ea4cdbfd79a0a6ff7af32a 308 SUPERFAMILY SSF53850 102 305 1.24E-37 T 10-03-2017 RG49_RS22150 d4fa617428ea4cdbfd79a0a6ff7af32a 308 SUPERFAMILY SSF46785 11 125 1.4E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22150 d4fa617428ea4cdbfd79a0a6ff7af32a 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 77 6.3E-16 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS22150 d4fa617428ea4cdbfd79a0a6ff7af32a 308 Gene3D G3DSA:3.40.190.10 95 210 2.9E-19 T 10-03-2017 RG49_RS22150 d4fa617428ea4cdbfd79a0a6ff7af32a 308 Gene3D G3DSA:3.40.190.10 211 274 9.9E-12 T 10-03-2017 RG49_RS07940 c8ed8e7556b5f1f4636fac6ec644e2e8 362 Pfam PF05036 Sporulation related domain 287 359 1.5E-16 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS07940 c8ed8e7556b5f1f4636fac6ec644e2e8 362 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 81 180 6.7E-29 T 10-03-2017 IPR012997 Rare lipoprotein A RG49_RS07940 c8ed8e7556b5f1f4636fac6ec644e2e8 362 Gene3D G3DSA:3.30.70.1070 284 359 1.1E-16 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS07940 c8ed8e7556b5f1f4636fac6ec644e2e8 362 Pfam PF03330 Lytic transglycolase 79 166 6.1E-20 T 10-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain RG49_RS07940 c8ed8e7556b5f1f4636fac6ec644e2e8 362 SUPERFAMILY SSF110997 287 357 9.02E-16 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS07940 c8ed8e7556b5f1f4636fac6ec644e2e8 362 SUPERFAMILY SSF50685 79 160 2.41E-6 T 10-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 Gene3D G3DSA:3.40.50.150 432 700 2.5E-75 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 303 315 4.8E-5 T 10-03-2017 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 193 207 4.8E-5 T 10-03-2017 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 702 32.717 T 10-03-2017 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 Gene3D G3DSA:3.40.50.150 255 329 1.7E-29 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 Gene3D G3DSA:3.40.50.150 147 214 1.7E-29 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 SUPERFAMILY SSF53335 396 698 1.25E-69 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 475 658 7.6E-20 T 10-03-2017 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 Pfam PF01170 Putative RNA methylase family UPF0020 162 375 9.5E-66 T 10-03-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 SMART SM00981 56 154 1.2E-19 T 10-03-2017 IPR004114 THUMP domain GO:0003723 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 PIRSF PIRSF037618 1 702 1.5E-295 T 10-03-2017 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 Pfam PF02926 THUMP domain 23 153 2.9E-20 T 10-03-2017 IPR004114 THUMP domain GO:0003723 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 10-03-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 SUPERFAMILY SSF53335 145 217 1.32E-40 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS05980 7e23c1fcf603a5f63994d59b1ad64ad1 702 SUPERFAMILY SSF53335 258 373 1.32E-40 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS12615 bb284c6aff1d5699fb846380a230d7e9 167 Gene3D G3DSA:3.40.630.30 10 166 1.0E-34 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS12615 bb284c6aff1d5699fb846380a230d7e9 167 Pfam PF00583 Acetyltransferase (GNAT) family 66 145 8.5E-14 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS12615 bb284c6aff1d5699fb846380a230d7e9 167 SUPERFAMILY SSF55729 10 166 1.72E-31 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS01635 ca0647c84305dfe2988424c49a3ce710 406 Gene3D G3DSA:3.90.1150.10 285 400 1.7E-26 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS01635 ca0647c84305dfe2988424c49a3ce710 406 SUPERFAMILY SSF53383 4 402 4.17E-129 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS01635 ca0647c84305dfe2988424c49a3ce710 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 217 236 - T 10-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site RG49_RS01635 ca0647c84305dfe2988424c49a3ce710 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 7 405 5.3E-188 T 10-03-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 RG49_RS01635 ca0647c84305dfe2988424c49a3ce710 406 Gene3D G3DSA:3.40.640.10 38 284 1.8E-87 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS01635 ca0647c84305dfe2988424c49a3ce710 406 Hamap MF_01831 Cysteine desulfurase [sufS]. 1 406 76.658 T 10-03-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 RG49_RS01635 ca0647c84305dfe2988424c49a3ce710 406 Pfam PF00266 Aminotransferase class-V 26 394 3.9E-157 T 10-03-2017 IPR000192 Aminotransferase class V domain RG49_RS14880 37aced325492a043241a67175c529092 310 Pfam PF01553 Acyltransferase 84 216 8.2E-14 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS14880 37aced325492a043241a67175c529092 310 SMART SM00563 97 224 2.6E-15 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS14880 37aced325492a043241a67175c529092 310 SUPERFAMILY SSF69593 19 296 6.93E-25 T 10-03-2017 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 Pfam PF00797 N-acetyltransferase 22 256 1.6E-86 T 10-03-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 1.4E-9 T 10-03-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 1.4E-9 T 10-03-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 151 170 1.4E-9 T 10-03-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 101 126 1.4E-9 T 10-03-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 1.4E-9 T 10-03-2017 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 Gene3D G3DSA:3.30.2140.10 3 85 1.3E-53 T 10-03-2017 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 Gene3D G3DSA:3.30.2140.10 182 259 1.3E-53 T 10-03-2017 RG49_RS03045 5a35b58ce0b9b3256def8071f67ef3a8 281 SUPERFAMILY SSF54001 2 269 9.61E-90 T 10-03-2017 RG49_RS08550 a1ef8771fae9935051929a9f52b34c79 308 Gene3D G3DSA:3.40.190.10 183 256 3.7E-9 T 10-03-2017 RG49_RS08550 a1ef8771fae9935051929a9f52b34c79 308 SUPERFAMILY SSF46785 3 88 4.64E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08550 a1ef8771fae9935051929a9f52b34c79 308 Gene3D G3DSA:1.10.10.10 2 88 1.3E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08550 a1ef8771fae9935051929a9f52b34c79 308 SUPERFAMILY SSF53850 105 292 4.34E-21 T 10-03-2017 RG49_RS08550 a1ef8771fae9935051929a9f52b34c79 308 Gene3D G3DSA:3.40.190.10 105 182 2.7E-4 T 10-03-2017 RG49_RS08550 a1ef8771fae9935051929a9f52b34c79 308 Pfam PF03466 LysR substrate binding domain 91 290 1.7E-20 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS08550 a1ef8771fae9935051929a9f52b34c79 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.3E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 143 2.2E-45 T 10-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 101 114 8.8E-29 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 45 61 8.8E-29 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 9 26 8.8E-29 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 79 94 8.8E-29 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 117 132 8.8E-29 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 Gene3D G3DSA:3.40.50.270 6 147 1.1E-45 T 10-03-2017 RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 SUPERFAMILY SSF52788 5 146 9.29E-42 T 10-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily RG49_RS05795 e708f2101280a7bb3d02956365052fbb 148 SMART SM00226 7 145 1.6E-68 T 10-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 Gene3D G3DSA:3.30.70.1450 421 483 6.3E-8 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 Pfam PF00999 Sodium/hydrogen exchanger family 16 388 8.8E-61 T 10-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 Hamap MF_01075 K(+)/H(+) antiporter NhaP2 [nhaP2]. 1 576 50.531 T 10-03-2017 IPR023729 K(+)/H(+) antiporter NhaP2 GO:0005451|GO:0006812|GO:0006813|GO:0006884|GO:0016021 RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 SUPERFAMILY SSF56176 497 571 1.45E-8 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 Pfam PF03471 Transporter associated domain 493 571 2.5E-9 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 Gene3D G3DSA:3.30.465.10 497 570 3.5E-9 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 SMART SM01091 492 573 6.1E-14 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 Pfam PF02080 TrkA-C domain 421 483 2.6E-11 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS04705 0597b12cc00b509d8d43bb0dd1f7074f 578 SUPERFAMILY SSF116726 417 483 6.54E-11 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 10-03-2017 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 Gene3D G3DSA:3.40.50.300 1 212 6.3E-83 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 Pfam PF05191 Adenylate kinase, active site lid 123 158 1.5E-15 T 10-03-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 1.5E-76 T 10-03-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 Hamap MF_00235 Adenylate kinase [adk]. 1 214 54.234 T 10-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 Pfam PF00406 Adenylate kinase 5 186 6.8E-61 T 10-03-2017 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 SUPERFAMILY SSF52540 1 213 4.91E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 PRINTS PR00094 Adenylate kinase signature 81 97 6.7E-36 T 10-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 PRINTS PR00094 Adenylate kinase signature 4 17 6.7E-36 T 10-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 PRINTS PR00094 Adenylate kinase signature 32 46 6.7E-36 T 10-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 PRINTS PR00094 Adenylate kinase signature 156 171 6.7E-36 T 10-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 RG49_RS08725 19579ce40a7e689d7eafceb415f215e8 214 PRINTS PR00094 Adenylate kinase signature 173 187 6.7E-36 T 10-03-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 RG49_RS01665 402741319af64e184ea35a8795010119 208 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01665 402741319af64e184ea35a8795010119 208 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 156 167 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01665 402741319af64e184ea35a8795010119 208 Pfam PF13247 4Fe-4S dicluster domain 116 195 4.4E-12 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS01665 402741319af64e184ea35a8795010119 208 SUPERFAMILY SSF54862 61 205 2.93E-37 T 10-03-2017 RG49_RS01665 402741319af64e184ea35a8795010119 208 Gene3D G3DSA:3.30.70.20 159 202 3.3E-13 T 10-03-2017 RG49_RS01665 402741319af64e184ea35a8795010119 208 Pfam PF12800 4Fe-4S binding domain 67 78 0.099 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS01665 402741319af64e184ea35a8795010119 208 Gene3D G3DSA:3.30.70.20 128 158 5.3E-11 T 10-03-2017 RG49_RS01665 402741319af64e184ea35a8795010119 208 Gene3D G3DSA:3.30.70.20 62 127 1.6E-10 T 10-03-2017 RG49_RS06510 d48fa010ac54350069b258ae5dacfefb 300 Pfam PF08443 RimK-like ATP-grasp domain 97 286 1.6E-83 T 10-03-2017 IPR013651 ATP-grasp fold, RimK-type RG49_RS06510 d48fa010ac54350069b258ae5dacfefb 300 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 55.195 T 10-03-2017 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK RG49_RS06510 d48fa010ac54350069b258ae5dacfefb 300 SUPERFAMILY SSF56059 98 288 9.16E-50 T 10-03-2017 RG49_RS06510 d48fa010ac54350069b258ae5dacfefb 300 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 6.7E-98 T 10-03-2017 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 RG49_RS06510 d48fa010ac54350069b258ae5dacfefb 300 Gene3D G3DSA:3.30.1490.20 103 173 5.9E-8 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS06510 d48fa010ac54350069b258ae5dacfefb 300 Gene3D G3DSA:3.30.470.20 174 277 1.4E-36 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS06510 d48fa010ac54350069b258ae5dacfefb 300 Gene3D G3DSA:3.40.50.20 8 102 2.4E-15 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS08340 c4cb08abdf5c541a14d22b1d619d13e7 153 SUPERFAMILY SSF55724 1 142 1.67E-37 T 10-03-2017 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 RG49_RS08340 c4cb08abdf5c541a14d22b1d619d13e7 153 Gene3D G3DSA:3.40.1000.10 1 146 2.2E-44 T 10-03-2017 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 RG49_RS08340 c4cb08abdf5c541a14d22b1d619d13e7 153 Pfam PF08786 Domain of unknown function (DUF1795) 7 137 1.3E-23 T 10-03-2017 IPR014894 Protein DcrB RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 Gene3D G3DSA:3.40.50.720 2 113 8.1E-31 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 SUPERFAMILY SSF51735 100 288 8.78E-58 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 319 1.6E-30 T 10-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 SUPERFAMILY SSF52283 1 133 4.73E-28 T 10-03-2017 RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 287 2.7E-62 T 10-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 Gene3D G3DSA:3.40.50.720 114 287 1.6E-65 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16720 303b91569818b7792b63ca148d2df81d 324 Hamap MF_01667 Glyoxylate/hydroxypyruvate reductase B [ghrB]. 1 324 76.147 T 10-03-2017 IPR023756 Glyoxylate/hydroxypyruvate reductase B GO:0016618|GO:0030267|GO:0055114 KEGG: 00260+1.1.1.81|KEGG: 00620+1.1.1.79|KEGG: 00630+1.1.1.79+1.1.1.81|MetaCyc: PWY-1622 RG49_RS24645 d6e24cd824f89a6c75dfbb87ef39f0c9 344 Gene3D G3DSA:2.60.40.1090 195 344 1.1E-7 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS24645 d6e24cd824f89a6c75dfbb87ef39f0c9 344 SUPERFAMILY SSF49401 194 344 2.98E-10 T 10-03-2017 IPR008966 Adhesion domain RG49_RS24645 d6e24cd824f89a6c75dfbb87ef39f0c9 344 PIRSF PIRSF030811 1 344 4.5E-165 T 10-03-2017 IPR016959 Uncharacterised conserved protein UCP030811 RG49_RS24645 d6e24cd824f89a6c75dfbb87ef39f0c9 344 Pfam PF00419 Fimbrial protein 183 343 3.8E-18 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS22810 7c6060b4ddb269f82f872ce2cfb38a7c 118 SUPERFAMILY SSF52833 1 115 6.81E-32 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS22810 7c6060b4ddb269f82f872ce2cfb38a7c 118 Gene3D G3DSA:3.40.30.10 1 115 4.9E-42 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS22810 7c6060b4ddb269f82f872ce2cfb38a7c 118 Pfam PF03960 ArsC family 5 114 2.9E-17 T 10-03-2017 IPR006660 Arsenate reductase-like RG49_RS22810 7c6060b4ddb269f82f872ce2cfb38a7c 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 115 1.5E-34 T 10-03-2017 IPR006504 Transcriptional regulator Spx/MgsR RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 Gene3D G3DSA:1.20.1250.20 20 186 3.5E-18 T 10-03-2017 RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 Hamap MF_01880 Dipeptide permease D [dtpD]. 1 493 63.872 T 10-03-2017 IPR023777 Amino acid/peptide transporter family, dipeptide permease D GO:0005887|GO:0042938 RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 140 152 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 65 89 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 Pfam PF00854 POT family 77 443 1.2E-96 T 10-03-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 6 463 3.6E-79 T 10-03-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 SUPERFAMILY SSF103473 260 480 2.35E-27 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS07545 2dcd81bb8bc7273f9c8051241c2ef1dd 493 SUPERFAMILY SSF103473 7 206 2.35E-27 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 Pfam PF00990 Diguanylate cyclase, GGDEF domain 297 452 2.2E-50 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 Gene3D G3DSA:3.30.70.270 298 458 9.2E-52 T 10-03-2017 RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 SUPERFAMILY SSF55073 300 456 1.18E-46 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 Pfam PF11563 Protoglobin 24 155 1.3E-9 T 10-03-2017 RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 297 455 5.7E-53 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 Gene3D G3DSA:1.10.490.10 19 152 1.7E-15 T 10-03-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 SMART SM00267 283 456 2.7E-71 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02880 b2cd9c6510aebc7d393c832dbc8f0778 460 SUPERFAMILY SSF46458 5 152 7.19E-23 T 10-03-2017 IPR009050 Globin-like RG49_RS06345 3cfca27767229b6aaa0738a6149bd45a 106 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 14 101 28.512 T 10-03-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS RG49_RS06345 3cfca27767229b6aaa0738a6149bd45a 106 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 102 5.0E-34 T 10-03-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 RG49_RS06345 3cfca27767229b6aaa0738a6149bd45a 106 SUPERFAMILY SSF54736 22 105 1.99E-33 T 10-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like RG49_RS06345 3cfca27767229b6aaa0738a6149bd45a 106 Gene3D G3DSA:3.30.1390.10 4 106 2.7E-45 T 10-03-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 7.5E-8 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 7.5E-8 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 Pfam PF07702 UTRA domain 93 229 2.2E-36 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 SUPERFAMILY SSF64288 59 236 5.18E-47 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 Gene3D G3DSA:1.10.10.10 3 66 7.2E-30 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 SMART SM00866 90 229 6.3E-34 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 Gene3D G3DSA:3.40.1410.10 67 236 4.0E-49 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 SUPERFAMILY SSF46785 2 73 2.91E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 SMART SM00345 10 69 8.2E-27 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS07405 de55ad8c088780dddf5316c1b3a3ed56 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 1.3E-24 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS21955 3bac1bedfe1fa3f39f582def0ca2d035 292 Gene3D G3DSA:3.40.50.10330 1 149 2.1E-41 T 10-03-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 RG49_RS21955 3bac1bedfe1fa3f39f582def0ca2d035 292 Pfam PF01513 ATP-NAD kinase 8 271 9.0E-80 T 10-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 RG49_RS21955 3bac1bedfe1fa3f39f582def0ca2d035 292 Gene3D G3DSA:2.60.200.30 150 261 7.9E-42 T 10-03-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 RG49_RS21955 3bac1bedfe1fa3f39f582def0ca2d035 292 SUPERFAMILY SSF111331 7 289 4.84E-92 T 10-03-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain RG49_RS21955 3bac1bedfe1fa3f39f582def0ca2d035 292 Hamap MF_00361 NAD kinase [nadK]. 6 287 32.904 T 10-03-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 RG49_RS23385 d5af549ce6b88312c9990806155953c4 187 Gene3D G3DSA:2.60.40.1090 30 186 3.6E-31 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS23385 d5af549ce6b88312c9990806155953c4 187 SUPERFAMILY SSF49401 32 186 1.14E-26 T 10-03-2017 IPR008966 Adhesion domain RG49_RS23385 d5af549ce6b88312c9990806155953c4 187 Pfam PF00419 Fimbrial protein 34 186 3.4E-13 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS05145 5c96612253d5137046f0005b72e1e632 265 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 10-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 RG49_RS05145 5c96612253d5137046f0005b72e1e632 265 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 256 3.4E-97 T 10-03-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 RG49_RS05145 5c96612253d5137046f0005b72e1e632 265 SUPERFAMILY SSF51556 1 259 8.52E-89 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS05145 5c96612253d5137046f0005b72e1e632 265 Gene3D G3DSA:3.20.20.140 2 257 2.5E-86 T 10-03-2017 RG49_RS05145 5c96612253d5137046f0005b72e1e632 265 PIRSF PIRSF005902 1 259 2.4E-75 T 10-03-2017 IPR001130 TatD family GO:0016788 RG49_RS05145 5c96612253d5137046f0005b72e1e632 265 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 10-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 RG49_RS05145 5c96612253d5137046f0005b72e1e632 265 Pfam PF01026 TatD related DNase 4 255 1.3E-76 T 10-03-2017 IPR001130 TatD family GO:0016788 RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 40.477 T 10-03-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 Pfam PF12706 Beta-lactamase superfamily domain 36 154 9.1E-9 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 Pfam PF12706 Beta-lactamase superfamily domain 203 270 9.7E-7 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 Gene3D G3DSA:3.60.15.10 196 305 1.4E-84 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 Gene3D G3DSA:3.60.15.10 1 157 1.4E-84 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 2.7E-104 T 10-03-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 TIGRFAM TIGR02649 true_RNase_BN: ribonuclease BN 2 305 7.7E-209 T 10-03-2017 IPR013469 Ribonuclease BN GO:0016891|GO:0042779 RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 SUPERFAMILY SSF56281 1 304 5.69E-89 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS23750 e570b1ca4c4fc5bb1dd2c2ddbdf24052 305 SMART SM00849 18 212 0.0097 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 Pfam PF00970 Oxidoreductase FAD-binding domain 7 105 8.6E-14 T 10-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 SUPERFAMILY SSF63380 2 107 5.38E-23 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 Gene3D G3DSA:3.10.20.30 238 352 1.8E-32 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 267 341 1.9E-17 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 4 351 6.4E-180 T 10-03-2017 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 SUPERFAMILY SSF54292 235 350 3.91E-28 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 Pfam PF00175 Oxidoreductase NAD-binding domain 118 226 8.3E-16 T 10-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 299 307 - T 10-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 SUPERFAMILY SSF52343 94 242 1.83E-33 T 10-03-2017 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00410 Phenol hydroxylase reductase family signature 141 150 2.2E-7 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00410 Phenol hydroxylase reductase family signature 36 48 2.2E-7 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00410 Phenol hydroxylase reductase family signature 116 135 2.2E-7 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 220 2.2E-7 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 Gene3D G3DSA:2.40.30.10 2 94 4.9E-24 T 10-03-2017 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 Gene3D G3DSA:3.40.50.80 95 237 6.9E-38 T 10-03-2017 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 220 1.8E-7 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 36 46 1.8E-7 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 55 62 1.8E-7 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 116 135 1.8E-7 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS03435 85cb8ff0051ccca0f6416e5c7ea5dc28 356 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 141 150 1.8E-7 T 10-03-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 RG49_RS02825 9efbcf904cd37e5785a5809f27b1297d 253 SUPERFAMILY SSF46689 186 235 1.52E-9 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02825 9efbcf904cd37e5785a5809f27b1297d 253 Pfam PF12833 Helix-turn-helix domain 157 230 1.1E-14 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS02825 9efbcf904cd37e5785a5809f27b1297d 253 SMART SM00342 150 231 1.8E-28 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS02825 9efbcf904cd37e5785a5809f27b1297d 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 215 231 9.9E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS02825 9efbcf904cd37e5785a5809f27b1297d 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 200 215 9.9E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS02825 9efbcf904cd37e5785a5809f27b1297d 253 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 186 227 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS02825 9efbcf904cd37e5785a5809f27b1297d 253 Gene3D G3DSA:1.10.10.60 186 233 5.0E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS06610 3b0cf15bb64aa4374589e5620de54002 302 PIRSF PIRSF020481 1 302 8.4E-131 T 10-03-2017 IPR014507 Baseplate assembly protein J, predicted RG49_RS06610 3b0cf15bb64aa4374589e5620de54002 302 Pfam PF04865 Baseplate J-like protein 118 261 1.2E-25 T 10-03-2017 IPR006949 Baseplate protein J-like RG49_RS13900 a2b7d74a606c977e38ee397d4744ffa9 136 Hamap MF_01048 Protein PsiE [psiE]. 3 136 25.356 T 10-03-2017 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 RG49_RS13900 a2b7d74a606c977e38ee397d4744ffa9 136 Pfam PF06146 Phosphate-starvation-inducible E 63 123 1.6E-16 T 10-03-2017 IPR020948 Phosphate-starvation-induced PsiE-like RG49_RS13900 a2b7d74a606c977e38ee397d4744ffa9 136 PIRSF PIRSF029598 1 136 7.0E-53 T 10-03-2017 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 RG49_RS10750 4c991d24375147672387b8f55871976f 452 SMART SM00257 342 385 1.4E-16 T 10-03-2017 IPR018392 LysM domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 SMART SM00257 401 443 4.6E-13 T 10-03-2017 IPR018392 LysM domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 121 149 - T 10-03-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 RG49_RS10750 4c991d24375147672387b8f55871976f 452 SUPERFAMILY SSF54106 341 384 9.29E-12 T 10-03-2017 IPR018392 LysM domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 SUPERFAMILY SSF53955 99 249 1.13E-41 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 Gene3D G3DSA:1.10.530.10 97 257 2.1E-47 T 10-03-2017 RG49_RS10750 4c991d24375147672387b8f55871976f 452 SUPERFAMILY SSF54106 400 443 2.49E-10 T 10-03-2017 IPR018392 LysM domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 Pfam PF01464 Transglycosylase SLT domain 102 216 1.1E-29 T 10-03-2017 IPR008258 Transglycosylase SLT domain 1 RG49_RS10750 4c991d24375147672387b8f55871976f 452 Gene3D G3DSA:3.10.350.10 399 443 1.2E-17 T 10-03-2017 IPR018392 LysM domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 Gene3D G3DSA:3.10.350.10 340 384 9.9E-20 T 10-03-2017 IPR018392 LysM domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 Pfam PF01476 LysM domain 343 384 2.2E-14 T 10-03-2017 IPR018392 LysM domain RG49_RS10750 4c991d24375147672387b8f55871976f 452 Pfam PF01476 LysM domain 402 441 1.1E-9 T 10-03-2017 IPR018392 LysM domain RG49_RS15770 09650e1c79f207c95b3adde3b3baf50f 430 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 23 423 5.9E-149 T 10-03-2017 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS15770 09650e1c79f207c95b3adde3b3baf50f 430 Gene3D G3DSA:1.20.1250.20 11 195 6.1E-47 T 10-03-2017 RG49_RS15770 09650e1c79f207c95b3adde3b3baf50f 430 Pfam PF07690 Major Facilitator Superfamily 21 389 1.0E-55 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS15770 09650e1c79f207c95b3adde3b3baf50f 430 SUPERFAMILY SSF103473 7 426 3.4E-83 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15770 09650e1c79f207c95b3adde3b3baf50f 430 Gene3D G3DSA:1.20.1250.20 234 425 4.0E-27 T 10-03-2017 RG49_RS15770 09650e1c79f207c95b3adde3b3baf50f 430 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 22 405 1.3E-134 T 10-03-2017 RG49_RS21105 f2603744fde33f57a35b72612c21b015 450 Gene3D G3DSA:1.20.1250.20 245 442 6.0E-33 T 10-03-2017 RG49_RS21105 f2603744fde33f57a35b72612c21b015 450 Gene3D G3DSA:1.20.1250.20 14 214 3.2E-46 T 10-03-2017 RG49_RS21105 f2603744fde33f57a35b72612c21b015 450 Pfam PF07690 Major Facilitator Superfamily 25 318 1.4E-47 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS21105 f2603744fde33f57a35b72612c21b015 450 SUPERFAMILY SSF103473 13 444 1.96E-81 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS21105 f2603744fde33f57a35b72612c21b015 450 PIRSF PIRSF002808 2 448 1.2E-43 T 10-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS21105 f2603744fde33f57a35b72612c21b015 450 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 27 436 2.4E-162 T 10-03-2017 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS20185 11c49969ca0645947e202ae3164069ff 83 ProDom PD060540 YQGD INNER MEMBRANE ECS3817 1 83 3.0E-42 T 10-03-2017 IPR020263 Uncharacterised protein family YqgD RG49_RS20185 11c49969ca0645947e202ae3164069ff 83 Pfam PF10885 Protein of unknown function (DUF2684) 3 79 4.9E-22 T 10-03-2017 IPR020263 Uncharacterised protein family YqgD RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 SMART SM00342 206 289 2.4E-26 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 SUPERFAMILY SSF46689 244 291 1.3E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 9.8E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 9.8E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 SUPERFAMILY SSF51182 39 123 2.07E-12 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 Pfam PF12833 Helix-turn-helix domain 212 290 4.1E-19 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 Gene3D G3DSA:2.60.120.10 37 99 2.6E-10 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 285 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 Pfam PF07883 Cupin domain 40 99 1.4E-9 T 10-03-2017 IPR013096 Cupin 2, conserved barrel RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 TIGRFAM TIGR02297 HpaA: 4-hydroxyphenylacetate catabolism regulatory protein HpaA 6 290 1.7E-116 T 10-03-2017 IPR011983 4-hydroxyphenylacetate catabolism regulatory protein HpaA RG49_RS12225 c2ca83e94ca9d112631343851a28b064 296 Gene3D G3DSA:1.10.10.60 242 291 5.0E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS07375 9e441c32db8af40efbbc54336b0dd9dc 37 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 29 2.4E-20 T 10-03-2017 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 RG49_RS07375 9e441c32db8af40efbbc54336b0dd9dc 37 Pfam PF08173 Membrane bound YbgT-like protein 1 26 2.8E-15 T 10-03-2017 IPR012994 Membrane bound YbgT-like RG49_RS10320 45acbd6265a38bef624afc9f95980aee 116 SMART SM00507 53 107 7.1E-9 T 10-03-2017 IPR003615 HNH nuclease RG49_RS10320 45acbd6265a38bef624afc9f95980aee 116 Pfam PF01844 HNH endonuclease 66 112 2.6E-15 T 10-03-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 RG49_RS11405 a3ca7531d4c383960ac3b072581ef9e0 355 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 347 1.6E-113 T 10-03-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11405 a3ca7531d4c383960ac3b072581ef9e0 355 SUPERFAMILY SSF53756 6 353 6.28E-131 T 10-03-2017 RG49_RS11405 a3ca7531d4c383960ac3b072581ef9e0 355 Gene3D G3DSA:3.40.50.2000 5 196 1.7E-76 T 10-03-2017 RG49_RS11405 a3ca7531d4c383960ac3b072581ef9e0 355 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 353 35.031 T 10-03-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11405 a3ca7531d4c383960ac3b072581ef9e0 355 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 344 6.0E-37 T 10-03-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 RG49_RS11405 a3ca7531d4c383960ac3b072581ef9e0 355 Gene3D G3DSA:3.40.50.2000 254 334 2.9E-5 T 10-03-2017 RG49_RS11405 a3ca7531d4c383960ac3b072581ef9e0 355 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 9 145 5.4E-49 T 10-03-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS21805 211ea8169a83fa2cc50942a28bb7f51c 263 Gene3D G3DSA:3.20.20.80 26 240 1.1E-12 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS21805 211ea8169a83fa2cc50942a28bb7f51c 263 SUPERFAMILY SSF51445 34 240 4.22E-18 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS21805 211ea8169a83fa2cc50942a28bb7f51c 263 Pfam PF00128 Alpha amylase, catalytic domain 28 222 1.5E-4 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS22525 580de5d36d3d318676bc70348654eab1 456 Pfam PF02601 Exonuclease VII, large subunit 126 440 5.6E-105 T 10-03-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 RG49_RS22525 580de5d36d3d318676bc70348654eab1 456 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 7 443 30.655 T 10-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS22525 580de5d36d3d318676bc70348654eab1 456 Pfam PF13742 OB-fold nucleic acid binding domain 10 103 2.1E-32 T 10-03-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 RG49_RS22525 580de5d36d3d318676bc70348654eab1 456 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 11 359 2.4E-142 T 10-03-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 380 400 - T 10-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 28 693 50.074 T 10-03-2017 IPR022946 Uncharacterised protein family UPF0313 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 SMART SM00729 376 623 4.1E-5 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 SUPERFAMILY SSF102114 377 440 1.18E-10 T 10-03-2017 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 SUPERFAMILY SSF102114 470 624 1.18E-10 T 10-03-2017 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 Pfam PF04055 Radical SAM superfamily 380 585 1.5E-19 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 Pfam PF11842 Domain of unknown function (DUF3362) 594 724 7.8E-45 T 10-03-2017 IPR024560 Uncharacterised protein family UPF0313, C-terminal RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 Pfam PF08497 Radical SAM N-terminal 29 379 4.0E-146 T 10-03-2017 IPR013704 Uncharacterised protein family UPF0313, N-terminal RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 29 644 1.5E-266 T 10-03-2017 IPR022946 Uncharacterised protein family UPF0313 RG49_RS19675 d3bef5dc5d72fe9c310c111d7432b379 739 Gene3D G3DSA:3.80.30.20 374 642 3.4E-47 T 10-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 Gene3D G3DSA:3.40.50.300 45 108 1.1E-7 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 Gene3D G3DSA:3.40.50.300 156 168 1.1E-7 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 SUPERFAMILY SSF52540 46 164 5.16E-12 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 13 319 2.5E-112 T 10-03-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 19 322 4.9E-126 T 10-03-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 322 40.44 T 10-03-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 Gene3D G3DSA:3.40.50.1000 239 286 7.8E-4 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06160 d78d68c2a6c0e7c62a5963d78295cb1f 328 Gene3D G3DSA:3.40.50.1000 128 133 7.8E-4 T 10-03-2017 IPR023214 HAD-like domain RG49_RS03430 068abca323794bdfe8432b8d5ba266c3 255 SUPERFAMILY SSF52096 2 255 1.77E-84 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS03430 068abca323794bdfe8432b8d5ba266c3 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 10-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 RG49_RS03430 068abca323794bdfe8432b8d5ba266c3 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 254 1.1E-76 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS03430 068abca323794bdfe8432b8d5ba266c3 255 Gene3D G3DSA:3.90.226.10 2 253 1.7E-89 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS15860 433a8c5b0af0a8dcf80c06fdde693613 394 SUPERFAMILY SSF103473 5 388 3.14E-56 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15860 433a8c5b0af0a8dcf80c06fdde693613 394 Pfam PF07690 Major Facilitator Superfamily 14 349 1.8E-39 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS15860 433a8c5b0af0a8dcf80c06fdde693613 394 TIGRFAM TIGR00880 2_A_01_02: multidrug resistance protein 50 186 2.8E-40 T 10-03-2017 IPR004734 Multidrug resistance protein GO:0015238|GO:0015893|GO:0016021 Reactome: R-HSA-442660 RG49_RS15860 433a8c5b0af0a8dcf80c06fdde693613 394 Gene3D G3DSA:1.20.1250.20 234 384 3.8E-4 T 10-03-2017 RG49_RS15860 433a8c5b0af0a8dcf80c06fdde693613 394 Gene3D G3DSA:1.20.1250.20 10 191 1.5E-29 T 10-03-2017 RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 Gene3D G3DSA:3.40.47.10 6 259 1.2E-54 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 SUPERFAMILY SSF53901 215 403 1.52E-60 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 10-03-2017 IPR018201 Beta-ketoacyl synthase, active site RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 Gene3D G3DSA:3.40.47.10 263 404 4.1E-49 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 SMART SM00825 Beta-ketoacyl synthase 4 406 7.9E-13 T 10-03-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 SUPERFAMILY SSF53901 1 253 5.76E-64 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 361 9.6E-30 T 10-03-2017 IPR014031 Beta-ketoacyl synthase, C-terminal RG49_RS23460 d6474761a2d8f2787d17c08775c8d77c 406 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 246 1.3E-39 T 10-03-2017 IPR014030 Beta-ketoacyl synthase, N-terminal RG49_RS21985 1b64f96e17b3232b18d4f8cfe5373512 82 SUPERFAMILY SSF54565 1 76 5.89E-29 T 10-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS21985 1b64f96e17b3232b18d4f8cfe5373512 82 Pfam PF00886 Ribosomal protein S16 8 68 1.1E-24 T 10-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS21985 1b64f96e17b3232b18d4f8cfe5373512 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 1.3E-28 T 10-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS21985 1b64f96e17b3232b18d4f8cfe5373512 82 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 10-03-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS21985 1b64f96e17b3232b18d4f8cfe5373512 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 24.165 T 10-03-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS21985 1b64f96e17b3232b18d4f8cfe5373512 82 Gene3D G3DSA:3.30.1320.10 1 78 1.1E-33 T 10-03-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 SUPERFAMILY SSF52540 3 189 4.01E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 SMART SM00072 3 187 3.6E-89 T 10-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 Gene3D G3DSA:3.40.50.300 18 43 3.3E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 10-03-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 Hamap MF_00328 Guanylate kinase [gmk]. 2 187 38.554 T 10-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 4 184 9.6E-77 T 10-03-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 Pfam PF00625 Guanylate kinase 5 186 1.2E-71 T 10-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 Gene3D G3DSA:3.40.50.300 88 204 2.8E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 Gene3D G3DSA:3.40.50.300 1 17 2.8E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16155 00a2e230767a7aebb667ea11577dad4b 207 Gene3D G3DSA:3.30.63.10 44 87 1.7E-30 T 10-03-2017 RG49_RS09485 1c117956dd932bba0dc42cc8709188d8 296 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 7 291 3.3E-138 T 10-03-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 RG49_RS09485 1c117956dd932bba0dc42cc8709188d8 296 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 250 1.9E-49 T 10-03-2017 RG49_RS09485 1c117956dd932bba0dc42cc8709188d8 296 SUPERFAMILY SSF51621 5 290 9.42E-99 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS09485 1c117956dd932bba0dc42cc8709188d8 296 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 4 292 50.752 T 10-03-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 RG49_RS09485 1c117956dd932bba0dc42cc8709188d8 296 Gene3D G3DSA:3.20.20.60 5 287 2.4E-101 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS09485 1c117956dd932bba0dc42cc8709188d8 296 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 10-03-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 Pfam PF02872 5'-nucleotidase, C-terminal domain 355 550 5.5E-25 T 10-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 TIGRFAM TIGR01390 CycNucDiestase: 2',3'-cyclic-nucleotide 2'-phosphodiesterase 22 647 0.0 T 10-03-2017 IPR006294 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase GO:0008663|GO:0009117 KEGG: 00230+3.1.4.16+3.1.3.6|KEGG: 00240+3.1.4.16+3.1.3.6 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 Gene3D G3DSA:3.90.780.10 360 596 1.6E-45 T 10-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 SUPERFAMILY SSF56300 19 353 5.13E-85 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 SUPERFAMILY SSF55816 355 597 3.79E-39 T 10-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 ProSitePatterns PS00786 5'-nucleotidase signature 2. 109 120 - T 10-03-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 ProSitePatterns PS00785 5'-nucleotidase signature 1. 24 36 - T 10-03-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 Pfam PF00149 Calcineurin-like phosphoesterase 24 259 2.6E-12 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 PRINTS PR01607 Apyrase family signature 215 232 5.7E-31 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 PRINTS PR01607 Apyrase family signature 530 549 5.7E-31 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 PRINTS PR01607 Apyrase family signature 428 451 5.7E-31 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 PRINTS PR01607 Apyrase family signature 22 40 5.7E-31 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 PRINTS PR01607 Apyrase family signature 243 266 5.7E-31 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 PRINTS PR01607 Apyrase family signature 283 303 5.7E-31 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS12810 34b73d0ab2bc50e9be155cee5e6e0faf 647 Gene3D G3DSA:3.60.21.10 12 359 8.9E-97 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS17375 4a37b1205d96b07b9f0e47e33b8e4e86 345 Gene3D G3DSA:3.30.360.10 146 336 1.6E-27 T 10-03-2017 RG49_RS17375 4a37b1205d96b07b9f0e47e33b8e4e86 345 Gene3D G3DSA:3.40.50.720 3 145 4.8E-42 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17375 4a37b1205d96b07b9f0e47e33b8e4e86 345 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 239 4.2E-16 T 10-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 RG49_RS17375 4a37b1205d96b07b9f0e47e33b8e4e86 345 SUPERFAMILY SSF55347 130 271 1.4E-20 T 10-03-2017 RG49_RS17375 4a37b1205d96b07b9f0e47e33b8e4e86 345 SUPERFAMILY SSF51735 3 158 1.48E-44 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17375 4a37b1205d96b07b9f0e47e33b8e4e86 345 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 120 8.0E-28 T 10-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 Gene3D G3DSA:3.30.2090.10 722 810 9.6E-23 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 Gene3D G3DSA:3.30.2090.10 181 275 3.9E-25 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82866 834 1026 7.32E-44 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82693 565 669 3.61E-29 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82693 135 182 2.35E-26 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82693 274 330 2.35E-26 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82866 296 497 5.36E-47 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82714 182 272 1.44E-20 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82693 672 722 8.89E-24 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82693 809 857 8.89E-24 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 Gene3D G3DSA:3.30.70.1430 567 670 2.8E-36 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 Gene3D G3DSA:1.10.3850.10 279 498 2.3E-57 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 Gene3D G3DSA:1.10.3850.10 815 1028 1.8E-54 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 Gene3D G3DSA:3.30.70.1430 38 139 5.2E-37 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82693 38 132 3.3E-28 T 10-03-2017 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 2.9E-112 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 SUPERFAMILY SSF82714 723 810 1.44E-18 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS16965 e5d2cfe417caffa915a0fa6a830e5037 1037 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1033 0.0 T 10-03-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 Gene3D G3DSA:3.40.190.10 20 108 6.3E-44 T 10-03-2017 RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 Gene3D G3DSA:3.40.190.10 203 242 6.3E-44 T 10-03-2017 RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 23 242 5.1E-71 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 Gene3D G3DSA:3.40.190.10 109 201 8.2E-30 T 10-03-2017 RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 SUPERFAMILY SSF53850 1 242 6.26E-74 T 10-03-2017 RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 241 3.6E-91 T 10-03-2017 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 SMART SM00062 22 242 2.4E-89 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 SMART SM00079 22 243 4.4E-4 T 10-03-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 RG49_RS06460 3a0c976b2231c7152391e91319e73a73 243 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 45 58 - T 10-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 RG49_RS22875 652505911fc59741fdcc7776a7e66dab 267 PIRSF PIRSF012294 1 255 5.1E-112 T 10-03-2017 IPR009194 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT-type GO:0005524|GO:0006580|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 RG49_RS22875 652505911fc59741fdcc7776a7e66dab 267 SUPERFAMILY SSF89028 93 249 1.1E-12 T 10-03-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 RG49_RS22875 652505911fc59741fdcc7776a7e66dab 267 Gene3D G3DSA:1.20.1200.10 95 248 1.0E-10 T 10-03-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 RG49_RS22875 652505911fc59741fdcc7776a7e66dab 267 Pfam PF01923 Cobalamin adenosyltransferase 95 246 5.9E-12 T 10-03-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 SUPERFAMILY SSF46785 9 70 2.15E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 SUPERFAMILY SSF48008 72 209 3.92E-18 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 Gene3D G3DSA:1.20.120.530 69 218 2.3E-25 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 Pfam PF07729 FCD domain 76 206 2.5E-20 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 Gene3D G3DSA:1.10.10.10 9 67 9.0E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 SMART SM00895 76 208 2.4E-18 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 66 2.5E-12 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS21770 0eff3dcdb6f0ee4910cadd8d9338a5eb 220 SMART SM00345 8 66 2.0E-17 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 SUPERFAMILY SSF63418 1 97 1.31E-28 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 Pfam PF08245 Mur ligase middle domain 106 292 4.5E-52 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 29 446 2.2E-143 T 10-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 394 1.8E-15 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 Gene3D G3DSA:3.40.1190.10 82 310 1.0E-76 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 SUPERFAMILY SSF53244 313 446 1.33E-37 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 447 34.721 T 10-03-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 Gene3D G3DSA:3.40.1390.10 1 80 1.8E-26 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 Pfam PF01225 Mur ligase family, catalytic domain 26 80 3.0E-9 T 10-03-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 SUPERFAMILY SSF53623 100 310 4.45E-60 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS11425 5396f3a33a06a69f91053c7c025f1ff8 452 Gene3D G3DSA:3.90.190.20 313 448 3.2E-45 T 10-03-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 10-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 PIRSF PIRSF006092 1 158 5.6E-56 T 10-03-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 Gene3D G3DSA:3.10.50.30 80 157 5.0E-33 T 10-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 SUPERFAMILY SSF46557 3 78 2.35E-29 T 10-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 7.7E-61 T 10-03-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 3.9E-32 T 10-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 SUPERFAMILY SSF54534 81 157 4.05E-25 T 10-03-2017 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 34.312 T 10-03-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 10-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 1.2E-29 T 10-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 RG49_RS18735 f95204fe2fc7c5121ae469e673ef6f03 158 Gene3D G3DSA:1.10.287.180 1 75 8.8E-36 T 10-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 RG49_RS09000 43b40eec41574e304aeb711bfdc83b82 163 Gene3D G3DSA:3.30.70.860 98 163 1.2E-35 T 10-03-2017 RG49_RS09000 43b40eec41574e304aeb711bfdc83b82 163 Gene3D G3DSA:3.30.70.990 9 97 6.1E-37 T 10-03-2017 RG49_RS09000 43b40eec41574e304aeb711bfdc83b82 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 163 30.408 T 10-03-2017 IPR007551 Protein of unknown function DUF520 RG49_RS09000 43b40eec41574e304aeb711bfdc83b82 163 Pfam PF04461 Protein of unknown function (DUF520) 2 162 1.6E-65 T 10-03-2017 IPR007551 Protein of unknown function DUF520 RG49_RS09000 43b40eec41574e304aeb711bfdc83b82 163 SUPERFAMILY SSF89963 2 89 2.88E-30 T 10-03-2017 IPR007551 Protein of unknown function DUF520 RG49_RS09000 43b40eec41574e304aeb711bfdc83b82 163 SUPERFAMILY SSF89963 91 163 1.99E-29 T 10-03-2017 IPR007551 Protein of unknown function DUF520 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 500 624 1.5E-46 T 10-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 SUPERFAMILY SSF55604 392 465 5.89E-18 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 Gene3D G3DSA:3.30.1360.60 390 466 6.3E-25 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 563 575 - T 10-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 463 2.2E-214 T 10-03-2017 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 405 422 - T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 Pfam PF00367 phosphotransferase system, EIIB 396 427 4.1E-12 T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 501 621 1.8E-47 T 10-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 360 452 7.0E-27 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 Pfam PF02378 Phosphotransferase system, EIIC 12 300 3.1E-74 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 Gene3D G3DSA:2.70.70.10 499 643 8.5E-56 T 10-03-2017 RG49_RS07720 28e585df6284dbff7a4aa07a411091b0 648 SUPERFAMILY SSF51261 497 646 2.44E-50 T 10-03-2017 IPR011055 Duplicated hybrid motif RG49_RS15920 fc6d51953f67c437bdd39958c2e4ad8e 463 SUPERFAMILY SSF103473 18 451 2.62E-57 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15920 fc6d51953f67c437bdd39958c2e4ad8e 463 Gene3D G3DSA:1.20.1250.20 30 231 2.7E-33 T 10-03-2017 RG49_RS15920 fc6d51953f67c437bdd39958c2e4ad8e 463 Gene3D G3DSA:1.20.1250.20 252 456 1.9E-29 T 10-03-2017 RG49_RS15920 fc6d51953f67c437bdd39958c2e4ad8e 463 PIRSF PIRSF002808 9 461 1.2E-100 T 10-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS15920 fc6d51953f67c437bdd39958c2e4ad8e 463 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 426 4.8E-145 T 10-03-2017 RG49_RS15920 fc6d51953f67c437bdd39958c2e4ad8e 463 ProSitePatterns PS00942 glpT family of transporters signature. 156 172 - T 10-03-2017 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-3229133|Reactome: R-HSA-70153 RG49_RS15920 fc6d51953f67c437bdd39958c2e4ad8e 463 Pfam PF07690 Major Facilitator Superfamily 35 397 3.5E-33 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS13835 3b188c398a3baedb4551e575bd27bb0b 290 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 5 288 30.375 T 10-03-2017 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 RG49_RS13835 3b188c398a3baedb4551e575bd27bb0b 290 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 67 89 - T 10-03-2017 IPR030470 UbiA prenyltransferase conserved site RG49_RS13835 3b188c398a3baedb4551e575bd27bb0b 290 Pfam PF01040 UbiA prenyltransferase family 28 271 1.9E-68 T 10-03-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 RG49_RS13835 3b188c398a3baedb4551e575bd27bb0b 290 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 11 287 4.1E-112 T 10-03-2017 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 Gene3D G3DSA:1.10.3860.10 6 406 3.8E-120 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 2 428 39.237 T 10-03-2017 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 295 318 - T 10-03-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site RG49_RS16880 db885011d46d91b8651a954e01f487be 428 SUPERFAMILY SSF118215 9 401 1.31E-121 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 Pfam PF00375 Sodium:dicarboxylate symporter family 9 401 1.2E-114 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 1.1E-37 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 1.1E-37 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 PRINTS PR00173 Glutamate-aspartate symporter signature 145 167 1.1E-37 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 PRINTS PR00173 Glutamate-aspartate symporter signature 192 211 1.1E-37 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 PRINTS PR00173 Glutamate-aspartate symporter signature 44 64 1.1E-37 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.1E-37 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 PRINTS PR00173 Glutamate-aspartate symporter signature 327 346 1.1E-37 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS16880 db885011d46d91b8651a954e01f487be 428 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 10-03-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site RG49_RS06435 3cce71b9bb9f5f5fa19189455ca5884d 171 Pfam PF12883 Protein of unknown function (DUF3828) 40 154 5.7E-28 T 10-03-2017 IPR024289 Domain of unknown function DUF3828 RG49_RS04285 1f1188d5fb1c600b0f1c9e3dd8f05eb8 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 263 2.4E-113 T 10-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS04285 1f1188d5fb1c600b0f1c9e3dd8f05eb8 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 38.772 T 10-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS04285 1f1188d5fb1c600b0f1c9e3dd8f05eb8 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 10-03-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS04285 1f1188d5fb1c600b0f1c9e3dd8f05eb8 268 Gene3D G3DSA:3.20.20.70 1 267 1.7E-99 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS04285 1f1188d5fb1c600b0f1c9e3dd8f05eb8 268 Pfam PF00290 Tryptophan synthase alpha chain 8 266 2.9E-102 T 10-03-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS04285 1f1188d5fb1c600b0f1c9e3dd8f05eb8 268 SUPERFAMILY SSF51366 1 266 8.95E-92 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 PIRSF PIRSF003059 2 559 5.9E-224 T 10-03-2017 IPR016377 Sucrose phosphorylase GO:0005985|GO:0009018 KEGG: 00500+2.4.1.7|MetaCyc: PWY-5384 RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 SMART SM00642 48 480 8.2E-6 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 SUPERFAMILY SSF51445 397 518 4.84E-77 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 SUPERFAMILY SSF51445 44 357 4.84E-77 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 Gene3D G3DSA:3.20.20.80 209 481 1.4E-109 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 Gene3D G3DSA:3.20.20.80 46 133 1.4E-109 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 Gene3D G3DSA:3.90.400.10 134 203 3.5E-24 T 10-03-2017 RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 Pfam PF00128 Alpha amylase, catalytic domain 83 338 1.6E-18 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS03995 561fb6c99a6640443f86ebd73f6bfc1c 559 Gene3D G3DSA:2.60.40.1180 491 559 2.6E-22 T 10-03-2017 IPR013780 Glycosyl hydrolase, all-beta RG49_RS05210 4351f757cf6aee852ca815343ae1137d 194 SUPERFAMILY SSF52972 1 185 6.34E-62 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS05210 4351f757cf6aee852ca815343ae1137d 194 Gene3D G3DSA:3.90.950.10 2 187 4.8E-62 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS05210 4351f757cf6aee852ca815343ae1137d 194 Hamap MF_00528 Septum formation protein Maf [maf]. 3 191 31.77 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS05210 4351f757cf6aee852ca815343ae1137d 194 PIRSF PIRSF006305 1 193 3.3E-46 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS05210 4351f757cf6aee852ca815343ae1137d 194 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 185 4.1E-75 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS05210 4351f757cf6aee852ca815343ae1137d 194 Pfam PF02545 Maf-like protein 3 186 5.9E-47 T 10-03-2017 IPR003697 Maf-like protein GO:0005737 RG49_RS19095 29e5a3b611b13a57961d86c92192eefc 383 Pfam PF13936 Helix-turn-helix domain 58 98 5.0E-18 T 10-03-2017 IPR025246 Transposase IS30-like HTH domain RG49_RS19095 29e5a3b611b13a57961d86c92192eefc 383 SUPERFAMILY SSF53098 229 375 9.67E-26 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS19095 29e5a3b611b13a57961d86c92192eefc 383 Gene3D G3DSA:3.30.420.10 231 375 6.2E-12 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS19095 29e5a3b611b13a57961d86c92192eefc 383 ProSitePatterns PS01043 Transposases, IS30 family, signature. 323 339 - T 10-03-2017 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 RG49_RS19095 29e5a3b611b13a57961d86c92192eefc 383 Pfam PF00665 Integrase core domain 230 336 2.3E-14 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS19070 6beb865147333d8feb1d2032a16213b6 192 Gene3D G3DSA:3.40.50.1390 3 129 5.6E-32 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS19070 6beb865147333d8feb1d2032a16213b6 192 ProSitePatterns PS00398 Site-specific recombinases signature 2. 64 76 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS19070 6beb865147333d8feb1d2032a16213b6 192 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS19070 6beb865147333d8feb1d2032a16213b6 192 SUPERFAMILY SSF53041 3 146 3.53E-36 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS19070 6beb865147333d8feb1d2032a16213b6 192 SMART SM00857 4 146 1.6E-47 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS19070 6beb865147333d8feb1d2032a16213b6 192 Pfam PF00239 Resolvase, N terminal domain 5 146 9.8E-35 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS16795 d03839ac745ddbaf94d5a9a460a0aa79 327 Pfam PF00005 ABC transporter 24 181 3.7E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS16795 d03839ac745ddbaf94d5a9a460a0aa79 327 SMART SM00382 32 231 6.1E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS16795 d03839ac745ddbaf94d5a9a460a0aa79 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 5.4E-28 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS16795 d03839ac745ddbaf94d5a9a460a0aa79 327 SUPERFAMILY SSF52540 31 307 1.18E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16795 d03839ac745ddbaf94d5a9a460a0aa79 327 Gene3D G3DSA:3.40.50.300 2 255 1.8E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16795 d03839ac745ddbaf94d5a9a460a0aa79 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 2.2E-18 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS16795 d03839ac745ddbaf94d5a9a460a0aa79 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24725 d8108be4134d1cb854b4ce6771983165 313 SUPERFAMILY SSF100950 59 311 9.21E-56 T 10-03-2017 RG49_RS24725 d8108be4134d1cb854b4ce6771983165 313 Gene3D G3DSA:3.40.50.1360 59 311 2.5E-62 T 10-03-2017 RG49_RS24725 d8108be4134d1cb854b4ce6771983165 313 Gene3D G3DSA:1.10.10.10 21 58 4.1E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24725 d8108be4134d1cb854b4ce6771983165 313 Pfam PF04198 Putative sugar-binding domain 59 311 6.2E-70 T 10-03-2017 IPR007324 Sugar-binding domain, putative GO:0030246 RG49_RS22160 b8672ff2ac54aece971fef3de6ae292e 245 SUPERFAMILY SSF53335 15 170 3.35E-27 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS22160 b8672ff2ac54aece971fef3de6ae292e 245 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS22160 b8672ff2ac54aece971fef3de6ae292e 245 Gene3D G3DSA:3.40.50.150 32 238 7.2E-38 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS22160 b8672ff2ac54aece971fef3de6ae292e 245 Pfam PF05175 Methyltransferase small domain 46 130 1.3E-12 T 10-03-2017 IPR007848 Methyltransferase small domain GO:0008168 RG49_RS22160 b8672ff2ac54aece971fef3de6ae292e 245 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 11 245 56.314 T 10-03-2017 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 KEGG: 00340+2.1.1.22 RG49_RS12035 dc03074bd4f6f15c2ac9ab19041df871 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 193 209 - T 10-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 RG49_RS12035 dc03074bd4f6f15c2ac9ab19041df871 260 Pfam PF01026 TatD related DNase 6 257 4.0E-68 T 10-03-2017 IPR001130 TatD family GO:0016788 RG49_RS12035 dc03074bd4f6f15c2ac9ab19041df871 260 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 5 13 - T 10-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 RG49_RS12035 dc03074bd4f6f15c2ac9ab19041df871 260 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 129 139 - T 10-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 RG49_RS12035 dc03074bd4f6f15c2ac9ab19041df871 260 PIRSF PIRSF005902 2 260 7.0E-74 T 10-03-2017 IPR001130 TatD family GO:0016788 RG49_RS12035 dc03074bd4f6f15c2ac9ab19041df871 260 Gene3D G3DSA:3.20.20.140 4 258 4.4E-80 T 10-03-2017 RG49_RS12035 dc03074bd4f6f15c2ac9ab19041df871 260 SUPERFAMILY SSF51556 5 258 1.38E-78 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 259 273 - T 10-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 Gene3D G3DSA:3.50.50.60 190 318 1.3E-120 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 Gene3D G3DSA:3.50.50.60 470 534 1.3E-120 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 Gene3D G3DSA:3.50.50.60 2 127 1.3E-120 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 SUPERFAMILY SSF54373 295 477 4.51E-67 T 10-03-2017 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 10-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 TIGRFAM TIGR01810 betA: choline dehydrogenase 4 537 0.0 T 10-03-2017 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 SUPERFAMILY SSF51905 2 293 9.36E-88 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 SUPERFAMILY SSF51905 476 535 9.36E-88 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 Pfam PF05199 GMC oxidoreductase 393 527 8.1E-42 T 10-03-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 Pfam PF00732 GMC oxidoreductase 3 300 6.1E-107 T 10-03-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 PIRSF PIRSF000137 1 539 3.8E-140 T 10-03-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 RG49_RS09625 890ba85b8b4c31bef9c6e43674142d4e 556 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 1 554 60.328 T 10-03-2017 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 SMART SM00851 19 132 1.4E-64 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 Pfam PF02142 MGS-like domain 19 132 6.9E-32 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 Gene3D G3DSA:3.40.140.20 253 371 1.3E-50 T 10-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 SUPERFAMILY SSF52335 7 197 9.03E-73 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 SMART SM00798 137 461 3.0E-217 T 10-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 SUPERFAMILY SSF53927 221 529 6.92E-131 T 10-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 Gene3D G3DSA:3.40.50.1380 5 190 1.4E-87 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 PIRSF PIRSF000414 1 529 4.7E-229 T 10-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 529 3.4E-274 T 10-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 Gene3D G3DSA:3.40.140.20 377 519 1.7E-60 T 10-03-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 529 45.601 T 10-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS14050 93ad988d60fa22a774eb6f08673a912f 529 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 460 2.3E-120 T 10-03-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS10450 0c28af08f388c25fb707c1589e8a1b57 387 Pfam PF00589 Phage integrase family 185 353 1.2E-46 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS10450 0c28af08f388c25fb707c1589e8a1b57 387 SUPERFAMILY SSF56349 57 361 5.3E-51 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS10450 0c28af08f388c25fb707c1589e8a1b57 387 Gene3D G3DSA:1.10.443.10 181 367 7.6E-42 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS22985 12246a5d4fc09952c26e955b8965a4f5 298 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 6 296 9.3E-156 T 10-03-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 RG49_RS22985 12246a5d4fc09952c26e955b8965a4f5 298 SUPERFAMILY SSF53697 6 249 3.78E-66 T 10-03-2017 RG49_RS22985 12246a5d4fc09952c26e955b8965a4f5 298 Gene3D G3DSA:3.40.50.10490 4 250 1.1E-83 T 10-03-2017 RG49_RS22985 12246a5d4fc09952c26e955b8965a4f5 298 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 185 202 - T 10-03-2017 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 RG49_RS22985 12246a5d4fc09952c26e955b8965a4f5 298 Pfam PF01380 SIS domain 128 208 1.1E-9 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS22985 12246a5d4fc09952c26e955b8965a4f5 298 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 2 295 42.088 T 10-03-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 Gene3D G3DSA:3.40.50.300 341 580 1.4E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 Pfam PF00664 ABC transporter transmembrane region 26 295 1.5E-41 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 Pfam PF00005 ABC transporter 357 505 6.0E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 SMART SM00382 366 557 9.9E-15 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 Gene3D G3DSA:1.20.1560.10 12 325 3.2E-77 T 10-03-2017 RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 SUPERFAMILY SSF52540 336 576 2.66E-79 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS08875 990c3944a53f9d4e20318df8fc0ec1ff 593 SUPERFAMILY SSF90123 12 325 2.62E-70 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS20860 5f414d399df3441134a17c6e35b3487a 346 Gene3D G3DSA:3.20.20.100 1 343 2.7E-105 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS20860 5f414d399df3441134a17c6e35b3487a 346 SUPERFAMILY SSF51430 1 344 1.15E-105 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS20860 5f414d399df3441134a17c6e35b3487a 346 Pfam PF00248 Aldo/keto reductase family 16 337 1.9E-72 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS20860 5f414d399df3441134a17c6e35b3487a 346 PRINTS PR00069 Aldo-keto reductase signature 164 181 2.9E-8 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS20860 5f414d399df3441134a17c6e35b3487a 346 PRINTS PR00069 Aldo-keto reductase signature 116 134 2.9E-8 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS11775 2a302b3fbcd9c036c43ca53c8991346d 301 Pfam PF03466 LysR substrate binding domain 99 286 3.6E-10 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS11775 2a302b3fbcd9c036c43ca53c8991346d 301 SUPERFAMILY SSF53850 92 289 6.79E-26 T 10-03-2017 RG49_RS11775 2a302b3fbcd9c036c43ca53c8991346d 301 Gene3D G3DSA:1.10.10.10 5 85 3.6E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS11775 2a302b3fbcd9c036c43ca53c8991346d 301 Gene3D G3DSA:3.40.190.10 99 229 2.0E-6 T 10-03-2017 RG49_RS11775 2a302b3fbcd9c036c43ca53c8991346d 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.2E-15 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS11775 2a302b3fbcd9c036c43ca53c8991346d 301 SUPERFAMILY SSF46785 1 87 4.46E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15285 fa6e681ea7fdb390b74a925ea49bceb0 348 Hamap MF_02025 ECA polysaccharide chain length modulation protein [wzzE]. 8 347 57.874 T 10-03-2017 IPR032895 ECA polysaccharide chain length modulation protein WzzE GO:0009246|GO:0016021 RG49_RS15285 fa6e681ea7fdb390b74a925ea49bceb0 348 SUPERFAMILY SSF160355 54 318 5.62E-88 T 10-03-2017 RG49_RS15285 fa6e681ea7fdb390b74a925ea49bceb0 348 Gene3D G3DSA:3.30.1890.10 257 318 1.7E-93 T 10-03-2017 RG49_RS15285 fa6e681ea7fdb390b74a925ea49bceb0 348 Gene3D G3DSA:3.30.1890.10 54 221 1.7E-93 T 10-03-2017 RG49_RS15285 fa6e681ea7fdb390b74a925ea49bceb0 348 Pfam PF02706 Chain length determinant protein 15 194 1.4E-14 T 10-03-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 SUPERFAMILY SSF47413 2 57 1.75E-18 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 SMART SM00354 2 72 4.0E-33 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 Gene3D G3DSA:3.40.50.2300 180 317 1.8E-33 T 10-03-2017 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 9.1E-7 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 9.1E-7 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 10-03-2017 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 Gene3D G3DSA:3.40.50.2300 52 179 5.3E-31 T 10-03-2017 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 Gene3D G3DSA:1.10.260.40 2 51 2.5E-25 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 77 321 2.7E-23 T 10-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 SUPERFAMILY SSF53822 75 325 4.88E-60 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS03940 824ecaee6b51f396712abd398e458f30 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.1E-21 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 SUPERFAMILY SSF52317 5 204 1.14E-58 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 Pfam PF02540 NAD synthase 223 257 1.2E-6 T 10-03-2017 IPR022310 NAD/GMP synthase RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 Pfam PF00117 Glutamine amidotransferase class-I 12 199 9.2E-42 T 10-03-2017 IPR017926 Glutamine amidotransferase RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 Gene3D G3DSA:3.40.50.880 3 223 1.8E-61 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 2.6E-6 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 2.6E-6 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 2.6E-6 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 1.1E-7 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.1E-7 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.1E-7 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 SUPERFAMILY SSF54810 405 525 1.44E-51 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 Gene3D G3DSA:3.30.300.10 401 525 1.0E-53 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 Pfam PF00958 GMP synthase C terminal domain 433 524 6.0E-44 T 10-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 56.667 T 10-03-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 Gene3D G3DSA:3.40.50.620 224 399 1.7E-58 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 9.4E-7 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 9.4E-7 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 9.4E-7 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 SUPERFAMILY SSF52402 197 420 3.97E-59 T 10-03-2017 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 212 525 2.0E-156 T 10-03-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 RG49_RS22535 694c6f10097223dd7c1fd8859599cbca 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 205 2.8E-85 T 10-03-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 288 3.4E-127 T 10-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 SUPERFAMILY SSF51569 1 292 1.0E-99 T 10-03-2017 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 288 4.7E-126 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 PIRSF PIRSF001365 1 292 1.7E-98 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 Gene3D G3DSA:3.20.20.70 1 292 8.4E-118 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 288 65.636 T 10-03-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 SMART SM01130 1 290 1.4E-141 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 5.9E-35 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 5.9E-35 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 5.9E-35 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 5.9E-35 T 10-03-2017 IPR002220 DapA-like GO:0008152|GO:0016829 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 10-03-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS22765 bb329795a06092d7524eb26961f2fade 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 10-03-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 SUPERFAMILY SSF52777 175 404 3.78E-90 T 10-03-2017 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 Gene3D G3DSA:2.40.50.100 1 96 7.6E-26 T 10-03-2017 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 Pfam PF02817 e3 binding domain 114 147 2.4E-12 T 10-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 Pfam PF00364 Biotin-requiring enzyme 5 76 4.2E-17 T 10-03-2017 IPR000089 Biotin/lipoyl attachment RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 Gene3D G3DSA:4.10.320.10 114 152 3.6E-20 T 10-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 175 403 1.9E-82 T 10-03-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 SUPERFAMILY SSF47005 106 151 1.83E-11 T 10-03-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 10-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 405 6.5E-196 T 10-03-2017 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 Gene3D G3DSA:3.30.559.10 165 403 1.7E-92 T 10-03-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 RG49_RS07420 e7d1fcbc78938f9ff5476c58816c821b 405 SUPERFAMILY SSF51230 2 95 3.14E-24 T 10-03-2017 IPR011053 Single hybrid motif RG49_RS18515 e53821ca4ede87a7a00588cae24a337d 291 Pfam PF00480 ROK family 4 288 1.2E-92 T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS18515 e53821ca4ede87a7a00588cae24a337d 291 Gene3D G3DSA:3.30.420.40 134 260 3.9E-41 T 10-03-2017 RG49_RS18515 e53821ca4ede87a7a00588cae24a337d 291 Hamap MF_01234 N-acetylmannosamine kinase [nanK]. 1 290 49.321 T 10-03-2017 IPR023945 N-acetylmannosamine kinase, bacterial GO:0005524|GO:0008270|GO:0009384|GO:0019262 KEGG: 00520+2.7.1.60|MetaCyc: PWY-6138 RG49_RS18515 e53821ca4ede87a7a00588cae24a337d 291 SUPERFAMILY SSF53067 1 287 3.0E-54 T 10-03-2017 RG49_RS18515 e53821ca4ede87a7a00588cae24a337d 291 ProSitePatterns PS01125 ROK family signature. 129 156 - T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS18515 e53821ca4ede87a7a00588cae24a337d 291 Gene3D G3DSA:3.30.420.40 2 133 6.2E-32 T 10-03-2017 RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 PIRSF PIRSF000292 1 313 2.8E-134 T 10-03-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 Gene3D G3DSA:1.10.287.90 29 113 4.4E-37 T 10-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 SUPERFAMILY SSF81464 29 116 8.18E-24 T 10-03-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 Pfam PF06481 COX Aromatic Rich Motif 239 285 9.2E-19 T 10-03-2017 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 149 218 2.2E-5 T 10-03-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 13 239 2.7E-124 T 10-03-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 Gene3D G3DSA:2.60.40.420 121 281 2.4E-42 T 10-03-2017 IPR008972 Cupredoxin RG49_RS08970 925c1148bd9b451cefa9b48d96afa4ef 315 SUPERFAMILY SSF49503 120 282 1.58E-54 T 10-03-2017 IPR008972 Cupredoxin RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 26 7.2E-4 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 Pfam PF13247 4Fe-4S dicluster domain 83 181 2.3E-24 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 Gene3D G3DSA:3.30.70.20 129 165 1.1E-14 T 10-03-2017 RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 SUPERFAMILY SSF54862 36 215 3.98E-64 T 10-03-2017 RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 Pfam PF00037 4Fe-4S binding domain 40 56 1.6E-4 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 TIGRFAM TIGR03149 cyt_nit_nrfC: cytochrome c nitrite reductase, Fe-S protein 2 222 1.1E-126 T 10-03-2017 IPR017567 Cytochrome c nitrite reductase, Fe-S protein RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 Gene3D G3DSA:3.30.70.20 36 95 7.8E-34 T 10-03-2017 RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 Gene3D G3DSA:3.30.70.20 166 210 7.8E-34 T 10-03-2017 RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 Gene3D G3DSA:3.30.70.20 96 128 6.1E-12 T 10-03-2017 RG49_RS13640 a06991b1dd66dc90411c3b5c494dd250 223 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 125 136 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS21945 9eddc944709ec6ef4afe37deef2da94e 113 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 4 112 34.055 T 10-03-2017 IPR026592 Outer membrane protein assembly factor BamE RG49_RS21945 9eddc944709ec6ef4afe37deef2da94e 113 Pfam PF04355 SmpA / OmlA family 35 104 4.3E-27 T 10-03-2017 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 SUPERFAMILY SSF52402 253 353 1.42E-5 T 10-03-2017 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 SUPERFAMILY SSF55874 719 885 1.1E-40 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS07620 9dacad23474b33facada4682d66dd949 894 SUPERFAMILY SSF47384 653 731 3.92E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Gene3D G3DSA:3.30.565.10 732 885 9.2E-39 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 776 882 1.1E-22 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Gene3D G3DSA:1.20.120.620 397 502 6.7E-40 T 10-03-2017 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Pfam PF13492 GAF domain 527 644 2.2E-8 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Gene3D G3DSA:3.40.50.300 21 229 1.4E-101 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Pfam PF13493 Domain of unknown function (DUF4118) 403 507 1.1E-28 T 10-03-2017 IPR025201 Sensor protein KdpD, transmembrane domain RG49_RS07620 9dacad23474b33facada4682d66dd949 894 SMART SM00387 773 883 4.9E-33 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Gene3D G3DSA:3.40.50.620 245 352 5.7E-7 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 21 230 8.6E-98 T 10-03-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 810 824 1.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 867 880 1.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 843 861 1.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 828 838 1.6E-12 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 SMART SM00388 663 730 1.4E-13 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Gene3D G3DSA:1.10.287.130 657 726 7.1E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS07620 9dacad23474b33facada4682d66dd949 894 Pfam PF00512 His Kinase A (phospho-acceptor) domain 664 730 1.5E-10 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS11835 f8cecc10df7ed11bb9a851ffecbbd625 188 Pfam PF01184 GPR1/FUN34/yaaH family 4 177 3.7E-41 T 10-03-2017 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 RG49_RS11835 f8cecc10df7ed11bb9a851ffecbbd625 188 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 8 17 - T 10-03-2017 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 RG49_RS13925 6bdf0a7fb72de4d1ff221f386b4c568f 212 Gene3D G3DSA:2.40.360.10 16 211 2.6E-81 T 10-03-2017 IPR023373 YmcC-like domain RG49_RS13925 6bdf0a7fb72de4d1ff221f386b4c568f 212 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 13 206 2.8E-62 T 10-03-2017 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB RG49_RS13925 6bdf0a7fb72de4d1ff221f386b4c568f 212 SUPERFAMILY SSF159270 20 208 3.66E-57 T 10-03-2017 IPR023373 YmcC-like domain RG49_RS23800 b8269084c70eea2a37aaa7afde26adf0 128 Hamap MF_00538 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF [arnF]. 1 125 20.352 T 10-03-2017 IPR022832 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF RG49_RS23800 b8269084c70eea2a37aaa7afde26adf0 128 SUPERFAMILY SSF103481 42 124 3.14E-5 T 10-03-2017 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 SUPERFAMILY SSF54675 14 130 2.33E-32 T 10-03-2017 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 PIRSF PIRSF006250 17 297 1.2E-115 T 10-03-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 131 295 4.1E-63 T 10-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 27 296 3.4E-105 T 10-03-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 Gene3D G3DSA:3.90.1170.20 20 151 4.8E-47 T 10-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 SUPERFAMILY SSF51690 131 296 9.81E-60 T 10-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 43 129 4.9E-24 T 10-03-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 RG49_RS11315 3f6a3d6ff2239a91fb28445f5e4c327c 297 Gene3D G3DSA:3.20.20.70 152 285 8.4E-60 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS17450 520074778e96358cf1772adade6b56c2 276 Gene3D G3DSA:1.20.1540.10 94 267 5.6E-39 T 10-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 RG49_RS17450 520074778e96358cf1772adade6b56c2 276 Pfam PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease 1 82 6.2E-29 T 10-03-2017 IPR022732 Peptidase S54, GlpG peptidase, N-terminal GO:0004252|GO:0016021 RG49_RS17450 520074778e96358cf1772adade6b56c2 276 Hamap MF_01594 Rhomboid protease GlpG [glpG]. 1 276 49.529 T 10-03-2017 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 RG49_RS17450 520074778e96358cf1772adade6b56c2 276 SUPERFAMILY SSF144091 92 267 3.53E-45 T 10-03-2017 RG49_RS17450 520074778e96358cf1772adade6b56c2 276 Pfam PF01694 Rhomboid family 131 269 5.1E-29 T 10-03-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 RG49_RS17450 520074778e96358cf1772adade6b56c2 276 TIGRFAM TIGR04239 rhombo_GlpG: rhomboid family protease GlpG 4 269 1.6E-116 T 10-03-2017 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 RG49_RS05665 6e2293f51bf49be253bf3bc3d5594159 442 TIGRFAM TIGR03616 RutG: pyrimidine utilization transport protein G 1 428 1.5E-256 T 10-03-2017 IPR019918 Pyrimidine permease RutG, predicted GO:0006864|GO:0015218 RG49_RS05665 6e2293f51bf49be253bf3bc3d5594159 442 Pfam PF00860 Permease family 31 401 1.9E-104 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS05665 6e2293f51bf49be253bf3bc3d5594159 442 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS05665 6e2293f51bf49be253bf3bc3d5594159 442 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 26 424 4.3E-119 T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 Gene3D G3DSA:3.40.50.300 230 345 1.9E-37 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 Gene3D G3DSA:3.40.50.300 1 171 1.9E-37 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 ProSitePatterns PS00618 RecF protein signature 2. 298 316 - T 10-03-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 10-03-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 SUPERFAMILY SSF52540 1 342 4.02E-40 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 357 98.277 T 10-03-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 355 7.4E-141 T 10-03-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 RG49_RS15725 173eedbbfd7d0508a102b28323e83932 357 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 354 1.7E-41 T 10-03-2017 IPR003395 RecF/RecN/SMC, N-terminal RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 6.9E-59 T 10-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 81 92 - T 10-03-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 58 69 - T 10-03-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 Gene3D G3DSA:3.90.1170.10 22 133 8.3E-53 T 10-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 133 38.018 T 10-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 6.4E-47 T 10-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 PRINTS PR00060 Ribosomal protein L16 signature 87 116 2.4E-40 T 10-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 PRINTS PR00060 Ribosomal protein L16 signature 57 86 2.4E-40 T 10-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 PRINTS PR00060 Ribosomal protein L16 signature 41 52 2.4E-40 T 10-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 PRINTS PR00060 Ribosomal protein L16 signature 23 35 2.4E-40 T 10-03-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18035 159e6ede332e7763b3b56f0b925339f5 136 SUPERFAMILY SSF54686 3 133 9.16E-55 T 10-03-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 RG49_RS16800 0c125115795bae7a1e6e7b32d8334b76 334 SMART SM00382 47 239 4.7E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS16800 0c125115795bae7a1e6e7b32d8334b76 334 SUPERFAMILY SSF52540 13 261 8.16E-73 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16800 0c125115795bae7a1e6e7b32d8334b76 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 306 6.4E-19 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS16800 0c125115795bae7a1e6e7b32d8334b76 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 324 3.9E-25 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS16800 0c125115795bae7a1e6e7b32d8334b76 334 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS16800 0c125115795bae7a1e6e7b32d8334b76 334 Pfam PF00005 ABC transporter 38 189 1.1E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS16800 0c125115795bae7a1e6e7b32d8334b76 334 Gene3D G3DSA:3.40.50.300 11 263 4.0E-81 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16390 a66101ab71808bb5be1ba9b7a1acbe27 551 Pfam PF02652 L-lactate permease 16 542 6.7E-234 T 10-03-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 RG49_RS16390 a66101ab71808bb5be1ba9b7a1acbe27 551 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 544 1.3E-240 T 10-03-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 RG49_RS16895 d1b9a14cf123ec8d34db0242ae100040 309 Gene3D G3DSA:3.40.1190.20 2 304 1.4E-77 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS16895 d1b9a14cf123ec8d34db0242ae100040 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS16895 d1b9a14cf123ec8d34db0242ae100040 309 SUPERFAMILY SSF53613 2 302 2.81E-74 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS16895 d1b9a14cf123ec8d34db0242ae100040 309 Pfam PF00294 pfkB family carbohydrate kinase 3 305 1.5E-74 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 Gene3D G3DSA:3.40.50.220 1 100 1.5E-32 T 10-03-2017 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 342 356 - T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 Gene3D G3DSA:3.90.100.10 586 711 5.0E-38 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 568 697 1.1E-46 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 SUPERFAMILY SSF53383 101 559 2.67E-124 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 Gene3D G3DSA:3.90.1150.10 413 585 7.0E-75 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 SUPERFAMILY SSF55904 563 711 2.62E-44 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 4 94 3.7E-14 T 10-03-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 PIRSF PIRSF009393 2 711 1.2E-287 T 10-03-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 101 543 1.4E-203 T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 SUPERFAMILY SSF52172 1 100 4.87E-26 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS20055 c6f8bbc7a65f88e9bb2756fddda0b9f7 711 Gene3D G3DSA:3.40.640.10 101 411 1.1E-115 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS00110 6d351951607845c4c3eba31dceb62f75 306 Pfam PF00892 EamA-like transporter family 14 140 8.2E-24 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS00110 6d351951607845c4c3eba31dceb62f75 306 Pfam PF00892 EamA-like transporter family 150 284 7.4E-19 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS00110 6d351951607845c4c3eba31dceb62f75 306 SUPERFAMILY SSF103481 196 287 7.06E-11 T 10-03-2017 RG49_RS00110 6d351951607845c4c3eba31dceb62f75 306 SUPERFAMILY SSF103481 43 144 1.83E-10 T 10-03-2017 RG49_RS00110 6d351951607845c4c3eba31dceb62f75 306 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 20 281 6.7E-71 T 10-03-2017 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 RG49_RS02990 fded196029b44ada5bba6206f2e6239e 167 Pfam PF03400 IS1 transposase 37 167 1.2E-77 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS09900 fded196029b44ada5bba6206f2e6239e 167 Pfam PF03400 IS1 transposase 37 167 1.2E-77 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS04875 fded196029b44ada5bba6206f2e6239e 167 Pfam PF03400 IS1 transposase 37 167 1.2E-77 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 SUPERFAMILY SSF46458 1 142 3.49E-38 T 10-03-2017 IPR009050 Globin-like RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 Gene3D G3DSA:2.40.30.10 149 254 7.8E-33 T 10-03-2017 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 SUPERFAMILY SSF52343 256 394 1.44E-37 T 10-03-2017 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 183 195 4.5E-6 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 256 4.5E-6 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 263 282 4.5E-6 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 358 366 4.5E-6 T 10-03-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 Pfam PF00175 Oxidoreductase NAD-binding domain 264 372 3.8E-17 T 10-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 Gene3D G3DSA:3.40.50.80 259 394 8.3E-36 T 10-03-2017 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 SUPERFAMILY SSF63380 148 253 4.43E-29 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 Gene3D G3DSA:1.10.490.10 2 140 1.6E-54 T 10-03-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 Pfam PF00042 Globin 7 103 7.3E-15 T 10-03-2017 IPR000971 Globin GO:0019825|GO:0020037 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 Hamap MF_01252 Flavohemoprotein [hmp]. 1 396 57.487 T 10-03-2017 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 RG49_RS22305 90ba0f935607a918dd3c749f201a1492 396 Pfam PF00970 Oxidoreductase FAD-binding domain 157 252 2.3E-9 T 10-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 RG49_RS04940 8f6df4cbac1e08437732c7f3ec5a4192 368 Gene3D G3DSA:3.40.50.620 3 211 6.6E-98 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS04940 8f6df4cbac1e08437732c7f3ec5a4192 368 Gene3D G3DSA:2.40.30.10 282 363 9.1E-34 T 10-03-2017 RG49_RS04940 8f6df4cbac1e08437732c7f3ec5a4192 368 SUPERFAMILY SSF52402 5 295 2.21E-57 T 10-03-2017 RG49_RS04940 8f6df4cbac1e08437732c7f3ec5a4192 368 Gene3D G3DSA:2.30.30.280 213 280 5.6E-35 T 10-03-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 RG49_RS04940 8f6df4cbac1e08437732c7f3ec5a4192 368 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 6 360 2.6E-161 T 10-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 RG49_RS04940 8f6df4cbac1e08437732c7f3ec5a4192 368 Pfam PF03054 tRNA methyl transferase 6 360 6.5E-145 T 10-03-2017 RG49_RS04940 8f6df4cbac1e08437732c7f3ec5a4192 368 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 6 361 40.978 T 10-03-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 SMART SM00382 361 547 1.4E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 Pfam PF00664 ABC transporter transmembrane region 22 291 6.0E-36 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 SUPERFAMILY SSF90123 7 327 6.8E-71 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 SUPERFAMILY SSF52540 326 572 7.38E-83 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 Pfam PF00005 ABC transporter 352 500 1.3E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 Gene3D G3DSA:1.20.1560.10 7 319 3.1E-70 T 10-03-2017 RG49_RS08880 16cbb19051321078d94300316a2b1e0e 590 Gene3D G3DSA:3.40.50.300 337 564 6.9E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 SUPERFAMILY SSF53067 6 265 1.52E-61 T 10-03-2017 RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 TIGRFAM TIGR01315 5C_CHO_kinase: FGGY-family pentulose kinase 6 533 2.3E-277 T 10-03-2017 IPR006003 Carbohydrate kinase, FGGY-related GO:0005975|GO:0016773 RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 Gene3D G3DSA:3.30.420.40 275 530 1.8E-58 T 10-03-2017 RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 PIRSF PIRSF000538 4 534 1.3E-79 T 10-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 SUPERFAMILY SSF53067 276 529 2.11E-53 T 10-03-2017 RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 264 2.0E-34 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 277 484 4.0E-48 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS24710 7fcc53ca025a7428a5843bf52e2acac5 534 Gene3D G3DSA:3.30.420.40 4 265 2.0E-73 T 10-03-2017 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 32 38 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 Pfam PF01555 DNA methylase 29 341 1.7E-41 T 10-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 Gene3D G3DSA:3.40.50.150 264 347 1.2E-60 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 Gene3D G3DSA:3.40.50.150 4 148 1.2E-60 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 28 42 7.5E-25 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 63 83 7.5E-25 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 325 345 7.5E-25 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 283 300 7.5E-25 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 302 320 7.5E-25 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 SUPERFAMILY SSF53335 267 345 2.31E-60 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS09830 b957d7d0068248f863498b04a8e6892a 350 SUPERFAMILY SSF53335 11 189 2.31E-60 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 SUPERFAMILY SSF81901 24 102 1.12E-11 T 10-03-2017 RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 SMART SM00671 35 66 3.3 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 SMART SM00671 67 101 14.0 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 SMART SM00671 179 216 3.6E-4 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 SMART SM00671 142 177 2.3E-5 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 Pfam PF08238 Sel1 repeat 85 101 68.0 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 Pfam PF08238 Sel1 repeat 180 215 2.2E-5 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 Pfam PF08238 Sel1 repeat 48 66 0.031 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 Pfam PF08238 Sel1 repeat 143 173 1.7E-4 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 Gene3D G3DSA:1.25.40.10 25 227 7.5E-33 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS13605 c1956ba4f44fc32d2743103cc50fac91 229 SUPERFAMILY SSF81901 85 215 1.74E-19 T 10-03-2017 RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 Pfam PF12800 4Fe-4S binding domain 136 155 0.033 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 Pfam PF12800 4Fe-4S binding domain 183 196 0.2 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 Gene3D G3DSA:1.10.1060.10 42 69 1.5E-9 T 10-03-2017 RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 Gene3D G3DSA:1.10.1060.10 155 196 1.5E-9 T 10-03-2017 RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 Gene3D G3DSA:3.30.70.20 70 105 3.4E-10 T 10-03-2017 RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 SUPERFAMILY SSF54862 59 204 9.0E-26 T 10-03-2017 RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 Gene3D G3DSA:3.30.70.20 106 154 3.5E-8 T 10-03-2017 RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 Pfam PF12838 4Fe-4S dicluster domain 60 115 2.1E-7 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24115 ca994a507e551f1af2be17e8723917e9 231 TIGRFAM TIGR00397 mauM_napG: MauM/NapG family ferredoxin-type protein 10 216 3.5E-71 T 10-03-2017 IPR004494 MauM/NapG ferredoxin-type protein RG49_RS14140 40613c31eea313212fb334ca96c6996d 377 SUPERFAMILY SSF102114 36 363 7.32E-53 T 10-03-2017 RG49_RS14140 40613c31eea313212fb334ca96c6996d 377 Pfam PF04055 Radical SAM superfamily 82 230 2.9E-9 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS14140 40613c31eea313212fb334ca96c6996d 377 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 258 360 7.2E-21 T 10-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 RG49_RS14140 40613c31eea313212fb334ca96c6996d 377 SMART SM00876 258 361 2.8E-27 T 10-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 RG49_RS14140 40613c31eea313212fb334ca96c6996d 377 Gene3D G3DSA:3.20.20.70 36 361 8.6E-47 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS14140 40613c31eea313212fb334ca96c6996d 377 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 3 368 2.1E-161 T 10-03-2017 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 RG49_RS20385 b8d23914181ff55fc2280029e8189235 129 SUPERFAMILY SSF51230 4 128 2.42E-46 T 10-03-2017 IPR011053 Single hybrid motif RG49_RS20385 b8d23914181ff55fc2280029e8189235 129 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 32.475 T 10-03-2017 IPR002930 Glycine cleavage system H-protein RG49_RS20385 b8d23914181ff55fc2280029e8189235 129 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 129 2.3E-61 T 10-03-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 RG49_RS20385 b8d23914181ff55fc2280029e8189235 129 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 10-03-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 RG49_RS20385 b8d23914181ff55fc2280029e8189235 129 Gene3D G3DSA:2.40.50.100 7 128 2.8E-52 T 10-03-2017 RG49_RS20385 b8d23914181ff55fc2280029e8189235 129 Pfam PF01597 Glycine cleavage H-protein 8 128 2.8E-50 T 10-03-2017 IPR002930 Glycine cleavage system H-protein RG49_RS07740 1a4dc8343b5f29efbb9a0fd6d8ec0df8 250 Gene3D G3DSA:3.40.50.10410 83 173 1.2E-31 T 10-03-2017 IPR023215 Nitrophenylphosphatase-like domain RG49_RS07740 1a4dc8343b5f29efbb9a0fd6d8ec0df8 250 Gene3D G3DSA:3.40.50.1000 1 79 3.6E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07740 1a4dc8343b5f29efbb9a0fd6d8ec0df8 250 Gene3D G3DSA:3.40.50.1000 174 247 3.6E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07740 1a4dc8343b5f29efbb9a0fd6d8ec0df8 250 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 105 1.8E-22 T 10-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA RG49_RS07740 1a4dc8343b5f29efbb9a0fd6d8ec0df8 250 Pfam PF13242 HAD-hyrolase-like 174 246 4.5E-20 T 10-03-2017 RG49_RS07740 1a4dc8343b5f29efbb9a0fd6d8ec0df8 250 SUPERFAMILY SSF56784 1 247 5.7E-65 T 10-03-2017 IPR023214 HAD-like domain RG49_RS07740 1a4dc8343b5f29efbb9a0fd6d8ec0df8 250 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 223 2.1E-65 T 10-03-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 SUPERFAMILY SSF52540 360 557 1.4E-33 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 SMART SM00382 392 561 1.5E-4 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 Pfam PF06472 ABC transporter transmembrane region 2 14 301 4.6E-48 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 Gene3D G3DSA:1.20.1560.10 32 350 5.7E-11 T 10-03-2017 RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 SUPERFAMILY SSF90123 35 349 1.2E-19 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 Pfam PF00005 ABC transporter 383 515 1.3E-18 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS02840 7cffa8a99a1213b1df7377350cc0dcfa 561 Gene3D G3DSA:3.40.50.300 368 557 1.1E-33 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 SUPERFAMILY SSF49354 27 144 3.14E-36 T 10-03-2017 IPR008962 PapD-like RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 SUPERFAMILY SSF49584 154 234 3.27E-15 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 Gene3D G3DSA:2.60.40.360 27 144 1.9E-40 T 10-03-2017 IPR008962 PapD-like RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 PRINTS PR00969 Pili chaperone signature 103 120 1.2E-23 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 PRINTS PR00969 Pili chaperone signature 164 179 1.2E-23 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 PRINTS PR00969 Pili chaperone signature 126 141 1.2E-23 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 PRINTS PR00969 Pili chaperone signature 27 36 1.2E-23 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 PRINTS PR00969 Pili chaperone signature 73 94 1.2E-23 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 27 144 3.2E-36 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 Gene3D G3DSA:2.60.40.1070 154 234 1.9E-18 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 102 119 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS19520 1c1bb2547f973c3d10eb4b3f1ae24acd 249 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 170 226 1.0E-7 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS23030 b2fa010e4341b27b468c57421675913c 124 ProDom PD031420 YFEK EXPORTED PRECURSOR SIGNAL PERIPLASMIC ECS3291 XCC0326 1 107 9.0E-59 T 10-03-2017 RG49_RS08580 09c651c59dcbe42b31ccf97d0d5d7cf8 122 Pfam PF15631 NTF2 fold immunity protein 55 122 1.2E-22 T 10-03-2017 IPR028921 NTF2 fold domain RG49_RS15065 2ef8dae2082ae3650d2ffd19c7a7060f 340 Pfam PF12146 Serine aminopeptidase, S33 52 312 1.8E-57 T 10-03-2017 IPR022742 Serine aminopeptidase, S33 RG49_RS15065 2ef8dae2082ae3650d2ffd19c7a7060f 340 Gene3D G3DSA:3.40.50.1820 29 329 1.5E-28 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS15065 2ef8dae2082ae3650d2ffd19c7a7060f 340 SUPERFAMILY SSF53474 17 329 2.73E-33 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS02950 4f56ef81d6622cc1f5000ca16467b31d 94 Gene3D G3DSA:1.10.260.40 1 81 1.6E-29 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02950 4f56ef81d6622cc1f5000ca16467b31d 94 Pfam PF01381 Helix-turn-helix 14 65 2.3E-8 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS02950 4f56ef81d6622cc1f5000ca16467b31d 94 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 81 1.3E-27 T 10-03-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 RG49_RS02950 4f56ef81d6622cc1f5000ca16467b31d 94 SUPERFAMILY SSF47413 9 88 7.04E-24 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02950 4f56ef81d6622cc1f5000ca16467b31d 94 SMART SM00530 12 67 6.6E-6 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 SUPERFAMILY SSF53671 18 372 1.57E-57 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 186 372 6.2E-41 T 10-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 21 177 1.3E-22 T 10-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 Gene3D G3DSA:3.40.50.1370 175 362 1.4E-58 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 322 331 2.7E-8 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 340 363 2.7E-8 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 66 85 2.7E-8 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 Gene3D G3DSA:3.40.50.1370 17 174 2.8E-32 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 56 78 3.7E-7 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 94 103 3.7E-7 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 163 180 3.7E-7 T 10-03-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS20560 995ff266c1b47085d0b0f20ba664298e 395 TIGRFAM TIGR03316 ygeW: knotted carbamoyltransferase YgeW 5 393 5.6E-204 T 10-03-2017 IPR017702 Putative carbamoyltransferase YgeW RG49_RS03445 ff03f8165dfba10e5c8adf9b932ddb24 248 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 11 248 4.3E-112 T 10-03-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 RG49_RS03445 ff03f8165dfba10e5c8adf9b932ddb24 248 Gene3D G3DSA:1.20.1260.10 2 248 1.4E-99 T 10-03-2017 IPR012347 Ferritin-related RG49_RS03445 ff03f8165dfba10e5c8adf9b932ddb24 248 Pfam PF05138 Phenylacetic acid catabolic protein 2 248 2.3E-95 T 10-03-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 RG49_RS03445 ff03f8165dfba10e5c8adf9b932ddb24 248 PIRSF PIRSF037834 1 248 5.5E-104 T 10-03-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 RG49_RS03445 ff03f8165dfba10e5c8adf9b932ddb24 248 SUPERFAMILY SSF47240 3 241 2.84E-84 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS23410 7e20236d2c1669f22a502751cd7a5506 179 SUPERFAMILY SSF49401 31 178 1.34E-27 T 10-03-2017 IPR008966 Adhesion domain RG49_RS23410 7e20236d2c1669f22a502751cd7a5506 179 Gene3D G3DSA:2.60.40.1090 31 178 1.6E-32 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS23410 7e20236d2c1669f22a502751cd7a5506 179 Pfam PF00419 Fimbrial protein 34 178 2.5E-17 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS04020 e704c2142dab9b1befcb173e95fc3a36 222 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 219 3.6E-92 T 10-03-2017 IPR014319 Phage shock protein, PspA RG49_RS04020 e704c2142dab9b1befcb173e95fc3a36 222 Pfam PF04012 PspA/IM30 family 2 216 1.1E-47 T 10-03-2017 IPR007157 PspA/IM30 RG49_RS20925 597443f5e272a0bebe1ff718dc35d025 107 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20925 597443f5e272a0bebe1ff718dc35d025 107 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 7.4E-6 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20925 597443f5e272a0bebe1ff718dc35d025 107 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 30 1.7E-6 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20925 597443f5e272a0bebe1ff718dc35d025 107 Pfam PF12528 Type II secretion prepilin peptidase dependent protein C 33 104 7.4E-24 T 10-03-2017 IPR022204 Prepilin peptidase dependent protein C RG49_RS09395 066f75165e952fb244545cc08873bf22 554 Pfam PF01494 FAD binding domain 16 352 3.1E-81 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 Gene3D G3DSA:3.50.50.60 15 192 2.5E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 Gene3D G3DSA:3.50.50.60 275 355 2.5E-53 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 7.9E-37 T 10-03-2017 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 7.9E-37 T 10-03-2017 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 7.9E-37 T 10-03-2017 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 338 7.9E-37 T 10-03-2017 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 7.9E-37 T 10-03-2017 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 7.9E-37 T 10-03-2017 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 Hamap MF_01652 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase [mhpA]. 7 554 68.968 T 10-03-2017 IPR023786 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase GO:0008688|GO:0019622|GO:0055114 KEGG: 00360+1.14.13.127|KEGG: 00362+1.14.13.12|KEGG: 00627+1.14.13.12|MetaCyc: PWY-6690 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 SUPERFAMILY SSF51905 274 388 5.76E-68 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09395 066f75165e952fb244545cc08873bf22 554 SUPERFAMILY SSF51905 16 187 5.76E-68 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 SUPERFAMILY SSF56176 204 289 2.73E-24 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 Gene3D G3DSA:3.10.580.10 55 196 1.1E-22 T 10-03-2017 RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 Pfam PF00571 CBS domain 69 124 6.1E-8 T 10-03-2017 IPR000644 CBS domain RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 Pfam PF00571 CBS domain 141 189 5.8E-5 T 10-03-2017 IPR000644 CBS domain RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 Pfam PF03471 Transporter associated domain 206 281 2.1E-23 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 SMART SM00116 78 127 4.2 T 10-03-2017 IPR000644 CBS domain RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 SMART SM00116 141 189 1.6 T 10-03-2017 IPR000644 CBS domain RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 Gene3D G3DSA:3.30.465.10 197 283 4.7E-31 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 SMART SM01091 205 283 1.1E-31 T 10-03-2017 IPR005170 Transporter-associated domain RG49_RS07815 1bc1abec4cdd9bfda2cc56666581251f 292 SUPERFAMILY SSF54631 66 202 4.67E-32 T 10-03-2017 RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 PIRSF PIRSF002764 1 220 6.1E-84 T 10-03-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 27 48 3.0E-72 T 10-03-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 193 216 3.0E-72 T 10-03-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 53 70 3.0E-72 T 10-03-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 156 175 3.0E-72 T 10-03-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 76 99 3.0E-72 T 10-03-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 101 119 3.0E-72 T 10-03-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 6 216 1.4E-95 T 10-03-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria RG49_RS24140 a5cdfba447e7093ce9dc19120de5ade9 220 Pfam PF03379 CcmB protein 3 217 4.8E-92 T 10-03-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 319 3.8E-60 T 10-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 Pfam PF14697 4Fe-4S dicluster domain 338 394 3.2E-17 T 10-03-2017 RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 SUPERFAMILY SSF51395 4 319 6.66E-70 T 10-03-2017 RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 Gene3D G3DSA:3.30.70.20 324 405 2.9E-16 T 10-03-2017 RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 Gene3D G3DSA:3.20.20.70 4 320 4.0E-80 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 Pfam PF01180 Dihydroorotate dehydrogenase 6 304 1.2E-34 T 10-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 378 389 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS24435 ca539dded8f9a8175a80b00dff11b052 411 SUPERFAMILY SSF54862 310 400 1.81E-21 T 10-03-2017 RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 Gene3D G3DSA:3.20.20.70 11 334 2.6E-49 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 265 345 9.7E-19 T 10-03-2017 IPR023885 4Fe4S-binding SPASM domain RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 Pfam PF13353 4Fe-4S single cluster domain 11 132 6.5E-7 T 10-03-2017 RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 158 371 2.0E-13 T 10-03-2017 RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 Pfam PF04055 Radical SAM superfamily 11 175 2.3E-15 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 2 364 3.1E-152 T 10-03-2017 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 SUPERFAMILY SSF102114 10 328 4.19E-44 T 10-03-2017 RG49_RS02835 b44ffaacb1a7258344e90e6c1e426e5f 385 Pfam PF13186 Iron-sulfur cluster-binding domain 263 318 4.8E-5 T 10-03-2017 IPR023885 4Fe4S-binding SPASM domain RG49_RS09005 6b68f148109cf622045d2398a272c212 303 Gene3D G3DSA:1.10.1040.10 175 290 6.4E-46 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS09005 6b68f148109cf622045d2398a272c212 303 SUPERFAMILY SSF48179 168 289 1.63E-39 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS09005 6b68f148109cf622045d2398a272c212 303 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 143 1.3E-24 T 10-03-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 RG49_RS09005 6b68f148109cf622045d2398a272c212 303 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 168 289 3.1E-38 T 10-03-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 RG49_RS09005 6b68f148109cf622045d2398a272c212 303 Gene3D G3DSA:3.40.50.720 1 174 8.1E-48 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09005 6b68f148109cf622045d2398a272c212 303 SUPERFAMILY SSF51735 1 167 1.6E-60 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09005 6b68f148109cf622045d2398a272c212 303 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 291 1.5E-75 T 10-03-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 RG49_RS21480 860858327148ec93a2d3de1c8c06c054 180 SUPERFAMILY SSF54862 18 116 6.7E-23 T 10-03-2017 RG49_RS21480 860858327148ec93a2d3de1c8c06c054 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS21480 860858327148ec93a2d3de1c8c06c054 180 Pfam PF12838 4Fe-4S dicluster domain 39 89 5.7E-13 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS21480 860858327148ec93a2d3de1c8c06c054 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS21480 860858327148ec93a2d3de1c8c06c054 180 Gene3D G3DSA:3.30.70.20 3 93 7.6E-21 T 10-03-2017 RG49_RS08675 670718b3f9e7158a436ca09545ac9556 131 Pfam PF01381 Helix-turn-helix 34 87 6.5E-10 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS08675 670718b3f9e7158a436ca09545ac9556 131 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 24 102 5.2E-31 T 10-03-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 RG49_RS08675 670718b3f9e7158a436ca09545ac9556 131 SUPERFAMILY SSF47413 29 105 6.14E-23 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS08675 670718b3f9e7158a436ca09545ac9556 131 Gene3D G3DSA:1.10.260.40 16 106 4.6E-32 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS08675 670718b3f9e7158a436ca09545ac9556 131 SMART SM00530 33 88 2.9E-9 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS11035 ef641f630db987af456f7d54f7bbfb7a 266 Pfam PF01497 Periplasmic binding protein 26 217 6.7E-25 T 10-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 RG49_RS11035 ef641f630db987af456f7d54f7bbfb7a 266 Gene3D G3DSA:3.40.50.1980 142 262 9.3E-36 T 10-03-2017 RG49_RS11035 ef641f630db987af456f7d54f7bbfb7a 266 Gene3D G3DSA:3.40.50.1980 24 138 1.9E-35 T 10-03-2017 RG49_RS11035 ef641f630db987af456f7d54f7bbfb7a 266 Hamap MF_01000 Vitamin B12-binding protein [btuF]. 2 266 48.581 T 10-03-2017 IPR023544 ABC transporter, vitamin B12-binding protein GO:0015889|GO:0031419|GO:0042597 RG49_RS11035 ef641f630db987af456f7d54f7bbfb7a 266 SUPERFAMILY SSF53807 25 262 2.75E-58 T 10-03-2017 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 261 275 - T 10-03-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 SUPERFAMILY SSF51735 1 147 1.06E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 SUPERFAMILY SSF55347 134 354 1.37E-78 T 10-03-2017 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 Gene3D G3DSA:3.30.360.10 143 350 8.5E-77 T 10-03-2017 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 2 366 3.3E-227 T 10-03-2017 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 SMART SM00859 3 122 2.2E-24 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 PIRSF PIRSF000148 1 367 2.0E-71 T 10-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 144 353 6.8E-61 T 10-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 367 34.33 T 10-03-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 Gene3D G3DSA:3.40.50.720 1 142 1.3E-67 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS17405 6214d45ce9b8a0c398874acaee29688e 367 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 120 4.6E-24 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS25175 e00b4c5a7f21fce594812b11ba189e40 131 Pfam PF04363 Protein of unknown function (DUF496) 30 121 5.5E-46 T 10-03-2017 IPR007458 Protein of unknown function DUF496 RG49_RS25175 e00b4c5a7f21fce594812b11ba189e40 131 ProDom PD030876 UPF0265 YEEX HELIX ALPHA BFL460 UNCHARACTERIZED FN0411 HI1168 VPA1226 BCR 33 120 2.0E-43 T 10-03-2017 IPR007458 Protein of unknown function DUF496 RG49_RS25175 e00b4c5a7f21fce594812b11ba189e40 131 Hamap MF_00683 UPF0265 protein YeeX [yeeX]. 30 124 25.713 T 10-03-2017 IPR007458 Protein of unknown function DUF496 RG49_RS25175 e00b4c5a7f21fce594812b11ba189e40 131 PIRSF PIRSF028773 23 131 1.4E-53 T 10-03-2017 IPR007458 Protein of unknown function DUF496 RG49_RS24255 e308e3496f6ed61fb59ce76f39976962 341 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 9 46 7.0E-6 T 10-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain RG49_RS24255 e308e3496f6ed61fb59ce76f39976962 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 158 338 4.4E-28 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24255 e308e3496f6ed61fb59ce76f39976962 341 SUPERFAMILY SSF161098 135 321 2.22E-18 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24255 e308e3496f6ed61fb59ce76f39976962 341 Gene3D G3DSA:1.10.3720.10 134 337 3.0E-17 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS22690 80e7febfcb2f4cd46680d6c9ef49e6a9 282 Gene3D G3DSA:1.20.1080.10 29 279 4.1E-81 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS22690 80e7febfcb2f4cd46680d6c9ef49e6a9 282 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 82 91 - T 10-03-2017 IPR024002 Formate/nitrite transporter, conserved site RG49_RS22690 80e7febfcb2f4cd46680d6c9ef49e6a9 282 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 26 279 2.7E-87 T 10-03-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 RG49_RS22690 80e7febfcb2f4cd46680d6c9ef49e6a9 282 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 167 177 - T 10-03-2017 IPR024002 Formate/nitrite transporter, conserved site RG49_RS22690 80e7febfcb2f4cd46680d6c9ef49e6a9 282 Pfam PF01226 Formate/nitrite transporter 20 273 4.7E-62 T 10-03-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 RG49_RS12915 d65578b90f9ff9693fd0afcf7c4d1870 91 Gene3D G3DSA:3.30.1660.10 23 91 1.1E-25 T 10-03-2017 IPR025543 Dodecin-like RG49_RS12915 d65578b90f9ff9693fd0afcf7c4d1870 91 SUPERFAMILY SSF159871 3 91 3.27E-24 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS12915 d65578b90f9ff9693fd0afcf7c4d1870 91 Pfam PF07338 Protein of unknown function (DUF1471) 36 91 2.0E-19 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS17935 e0cfeb5e390632c70f5684527b5f0475 153 Pfam PF04612 Type II secretion system (T2SS), protein M 2 150 4.2E-32 T 10-03-2017 IPR007690 Type II secretion system, protein M GO:0006858 RG49_RS17935 e0cfeb5e390632c70f5684527b5f0475 153 SUPERFAMILY SSF103054 76 139 3.14E-5 T 10-03-2017 IPR023229 Type II secretion system protein M, periplasmic domain RG49_RS12900 e5627408e2fc40eb9c6a1116a2708f64 104 PIRSF PIRSF003135 1 101 2.1E-50 T 10-03-2017 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 RG49_RS12900 e5627408e2fc40eb9c6a1116a2708f64 104 Gene3D G3DSA:2.40.50.140 1 103 2.1E-43 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS12900 e5627408e2fc40eb9c6a1116a2708f64 104 Pfam PF00436 Single-strand binding protein family 3 87 5.4E-13 T 10-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 RG49_RS12900 e5627408e2fc40eb9c6a1116a2708f64 104 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 3 99 1.6E-36 T 10-03-2017 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 RG49_RS12900 e5627408e2fc40eb9c6a1116a2708f64 104 Hamap MF_00720 Primosomal replication protein n [priB]. 1 100 30.683 T 10-03-2017 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 RG49_RS12900 e5627408e2fc40eb9c6a1116a2708f64 104 SUPERFAMILY SSF50249 1 103 1.75E-29 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18690 17762f76e0f81ac376f47293595200a3 84 Gene3D G3DSA:3.30.300.90 1 80 3.1E-27 T 10-03-2017 IPR002634 BolA protein RG49_RS18690 17762f76e0f81ac376f47293595200a3 84 SUPERFAMILY SSF82657 2 82 3.01E-28 T 10-03-2017 IPR002634 BolA protein RG49_RS18690 17762f76e0f81ac376f47293595200a3 84 Pfam PF01722 BolA-like protein 17 74 8.9E-14 T 10-03-2017 IPR002634 BolA protein RG49_RS18690 17762f76e0f81ac376f47293595200a3 84 PIRSF PIRSF003113 1 83 5.6E-21 T 10-03-2017 IPR002634 BolA protein RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 SUPERFAMILY SSF50447 563 644 7.9E-23 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 887 17.63 T 10-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Gene3D G3DSA:3.40.50.10050 690 768 4.1E-24 T 10-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Pfam PF00009 Elongation factor Tu GTP binding domain 394 550 3.4E-35 T 10-03-2017 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 SUPERFAMILY SSF46955 3 50 9.89E-12 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Gene3D G3DSA:3.30.56.50 2 50 9.8E-23 T 10-03-2017 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 SUPERFAMILY SSF52156 667 796 3.53E-37 T 10-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 ProSitePatterns PS01176 Initiation factor 2 signature. 840 862 - T 10-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Gene3D G3DSA:3.40.50.300 389 549 6.4E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 SUPERFAMILY SSF50447 791 887 3.73E-34 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 SUPERFAMILY SSF52540 389 557 4.21E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 393 548 4.8E-33 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 306 889 4.5E-298 T 10-03-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Gene3D G3DSA:2.40.30.10 791 887 3.4E-39 T 10-03-2017 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 314 364 6.9E-15 T 10-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 52 2.5E-7 T 10-03-2017 IPR006847 Translation initiation factor IF-2, N-terminal RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 56 94 4.9E-16 T 10-03-2017 IPR013575 Initiation factor 2 associated domain, bacterial RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Pfam PF11987 Translation-initiation factor 2 674 779 3.1E-36 T 10-03-2017 IPR023115 Translation initiation factor IF- 2, domain 3 RG49_RS18805 bf16af9c81402c4ccf167b4d9487a2d0 890 Gene3D G3DSA:2.40.30.10 563 653 5.7E-21 T 10-03-2017 RG49_RS17315 c5814737bb4fe183c9ad6a7ea8e039b1 438 Pfam PF13416 Bacterial extracellular solute-binding protein 44 368 4.2E-45 T 10-03-2017 RG49_RS17315 c5814737bb4fe183c9ad6a7ea8e039b1 438 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 140 157 - T 10-03-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 RG49_RS17315 c5814737bb4fe183c9ad6a7ea8e039b1 438 SUPERFAMILY SSF53850 25 425 2.74E-77 T 10-03-2017 RG49_RS17315 c5814737bb4fe183c9ad6a7ea8e039b1 438 Gene3D G3DSA:3.40.190.10 145 345 1.5E-42 T 10-03-2017 RG49_RS02900 97bcbd5598a0562f6e36fc3ffc4d63ed 340 SUPERFAMILY SSF161098 96 161 3.4E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS02900 97bcbd5598a0562f6e36fc3ffc4d63ed 340 SUPERFAMILY SSF161098 199 323 3.4E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS02900 97bcbd5598a0562f6e36fc3ffc4d63ed 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 334 7.1E-46 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS02900 97bcbd5598a0562f6e36fc3ffc4d63ed 340 Gene3D G3DSA:1.10.3720.10 202 331 6.7E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS02900 97bcbd5598a0562f6e36fc3ffc4d63ed 340 Gene3D G3DSA:1.10.3720.10 97 164 6.7E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS22495 8fdfc5b772bb357d9e57c9710e060f7e 372 Gene3D G3DSA:3.20.20.70 30 132 1.2E-9 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS22495 8fdfc5b772bb357d9e57c9710e060f7e 372 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 357 34.652 T 10-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 RG49_RS22495 8fdfc5b772bb357d9e57c9710e060f7e 372 Pfam PF04551 GcpE protein 14 353 7.7E-132 T 10-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 RG49_RS22495 8fdfc5b772bb357d9e57c9710e060f7e 372 SUPERFAMILY SSF51717 15 208 1.49E-10 T 10-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS22495 8fdfc5b772bb357d9e57c9710e060f7e 372 SUPERFAMILY SSF56014 265 350 9.81E-10 T 10-03-2017 RG49_RS22495 8fdfc5b772bb357d9e57c9710e060f7e 372 PIRSF PIRSF004640 1 363 2.0E-148 T 10-03-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 RG49_RS22495 8fdfc5b772bb357d9e57c9710e060f7e 372 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 350 7.5E-126 T 10-03-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 RG49_RS00675 371e11c9eb13cc1cb3010a66a98c6e68 603 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 602 0.0 T 10-03-2017 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 RG49_RS00675 371e11c9eb13cc1cb3010a66a98c6e68 603 SUPERFAMILY SSF143975 1 418 1.22E-146 T 10-03-2017 RG49_RS00675 371e11c9eb13cc1cb3010a66a98c6e68 603 SUPERFAMILY SSF52016 419 600 1.02E-57 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS00675 371e11c9eb13cc1cb3010a66a98c6e68 603 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 505 516 - T 10-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS00675 371e11c9eb13cc1cb3010a66a98c6e68 603 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 10-03-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS00675 371e11c9eb13cc1cb3010a66a98c6e68 603 Pfam PF00920 Dehydratase family 66 598 1.9E-158 T 10-03-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 Pfam PF07702 UTRA domain 91 230 1.1E-20 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 4.9E-8 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 4.9E-8 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 SMART SM00345 11 70 7.2E-20 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 SUPERFAMILY SSF46785 3 74 1.57E-15 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 1.1E-19 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 Gene3D G3DSA:1.10.10.10 3 67 2.6E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 Gene3D G3DSA:3.40.1410.10 68 234 1.2E-18 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 SMART SM00866 91 231 5.2E-11 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS14815 5001e585b1305abd33ffad482938cdf2 236 SUPERFAMILY SSF64288 60 234 1.21E-21 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 9 483 1.3E-183 T 10-03-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 145 157 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 70 94 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 Hamap MF_01879 Dipeptide and tripeptide permease B [dtpB]. 3 486 45.444 T 10-03-2017 IPR023778 Amino acid/peptide transporter family, dipeptide/tripeptide permease B RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 Pfam PF00854 POT family 82 443 7.0E-99 T 10-03-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 SUPERFAMILY SSF103473 244 481 1.57E-26 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 SUPERFAMILY SSF103473 8 200 1.57E-26 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 Gene3D G3DSA:1.20.1250.20 14 192 2.7E-15 T 10-03-2017 RG49_RS17070 d21f567ec6a15c020f7adcc23a64e978 489 Gene3D G3DSA:1.20.1250.20 279 477 4.7E-6 T 10-03-2017 RG49_RS16785 5564ce4abd1598e41a94c30ac6f888ed 339 Gene3D G3DSA:1.10.3720.10 87 162 8.3E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16785 5564ce4abd1598e41a94c30ac6f888ed 339 Gene3D G3DSA:1.10.3720.10 203 332 8.3E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16785 5564ce4abd1598e41a94c30ac6f888ed 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 336 2.3E-46 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16785 5564ce4abd1598e41a94c30ac6f888ed 339 SUPERFAMILY SSF161098 89 160 1.49E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16785 5564ce4abd1598e41a94c30ac6f888ed 339 SUPERFAMILY SSF161098 200 322 1.49E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07360 e1b790f28dbef9c8a05010b9baec1c32 230 TIGRFAM TIGR02796 tolQ: protein TolQ 5 219 1.0E-93 T 10-03-2017 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 RG49_RS07360 e1b790f28dbef9c8a05010b9baec1c32 230 Pfam PF01618 MotA/TolQ/ExbB proton channel family 79 207 6.7E-42 T 10-03-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 RG49_RS09500 b531e00f95f85a5ec05889314c227143 223 Pfam PF01810 LysE type translocator 29 219 8.9E-57 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS09500 b531e00f95f85a5ec05889314c227143 223 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 33 215 1.9E-71 T 10-03-2017 IPR004778 Homoserine/Threonine efflux protein GO:0016021 RG49_RS09500 b531e00f95f85a5ec05889314c227143 223 PIRSF PIRSF006324 14 220 4.3E-55 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 SUPERFAMILY SSF52540 23 236 1.48E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 83 98 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 PRINTS PR00315 GTP-binding elongation factor signature 126 137 6.2E-13 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 PRINTS PR00315 GTP-binding elongation factor signature 163 172 6.2E-13 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 PRINTS PR00315 GTP-binding elongation factor signature 110 120 6.2E-13 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 PRINTS PR00315 GTP-binding elongation factor signature 29 42 6.2E-13 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 PRINTS PR00315 GTP-binding elongation factor signature 90 98 6.2E-13 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 Gene3D G3DSA:3.40.50.300 21 236 9.4E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 Pfam PF00009 Elongation factor Tu GTP binding domain 27 231 1.7E-42 T 10-03-2017 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 34 214 1.6E-13 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 SUPERFAMILY SSF50447 244 328 2.43E-22 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 28 434 5.3E-213 T 10-03-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 SUPERFAMILY SSF50465 336 435 7.19E-30 T 10-03-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 19 475 53.886 T 10-03-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 RG49_RS21315 7b018704e074fee34e7a5f6016618c09 475 Gene3D G3DSA:2.40.30.10 244 359 4.9E-17 T 10-03-2017 RG49_RS24325 7bd5eb95b9c853157f4cb3a020d91cb2 313 Gene3D G3DSA:3.40.1190.20 6 305 1.5E-68 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24325 7bd5eb95b9c853157f4cb3a020d91cb2 313 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS24325 7bd5eb95b9c853157f4cb3a020d91cb2 313 SUPERFAMILY SSF53613 7 306 6.24E-60 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24325 7bd5eb95b9c853157f4cb3a020d91cb2 313 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 40 64 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS24325 7bd5eb95b9c853157f4cb3a020d91cb2 313 Pfam PF00294 pfkB family carbohydrate kinase 5 295 8.4E-66 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS18040 a7d6f728c27ff151616ca9b508e75108 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.555 T 10-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18040 a7d6f728c27ff151616ca9b508e75108 63 Pfam PF00831 Ribosomal L29 protein 4 60 5.7E-23 T 10-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18040 a7d6f728c27ff151616ca9b508e75108 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 4.3E-22 T 10-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18040 a7d6f728c27ff151616ca9b508e75108 63 SUPERFAMILY SSF46561 1 61 6.41E-22 T 10-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18040 a7d6f728c27ff151616ca9b508e75108 63 Gene3D G3DSA:1.10.287.310 1 60 5.4E-28 T 10-03-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18040 a7d6f728c27ff151616ca9b508e75108 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 10-03-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Gene3D G3DSA:1.10.1780.10 1 147 2.7E-48 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Gene3D G3DSA:3.40.50.300 160 341 2.3E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Gene3D G3DSA:1.10.8.60 778 855 2.4E-31 T 10-03-2017 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 10-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 SUPERFAMILY SSF52540 159 545 2.59E-99 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 337 1.0E-13 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Gene3D G3DSA:3.40.50.300 551 777 8.0E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Gene3D G3DSA:1.10.8.60 343 427 5.3E-37 T 10-03-2017 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 1.0E-28 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.6E-42 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 1.6E-42 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 1.6E-42 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 1.6E-42 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 8.7E-13 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 8.6E-13 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 SMART SM00382 597 752 2.2E-10 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 SMART SM00382 198 343 5.7E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 SUPERFAMILY SSF52540 546 853 7.34E-87 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 760 1.3E-55 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 854 0.0 T 10-03-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 SMART SM01086 766 855 1.2E-37 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 SUPERFAMILY SSF81923 4 156 1.29E-42 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS22065 d6ef643f0804ab84ab4a77a7091bab22 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 10-03-2017 IPR028299 ClpA/B, conserved site 2 RG49_RS21585 7b2ac6818f57078c1087def2c187a208 165 Gene3D G3DSA:3.90.950.20 3 163 8.1E-63 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS21585 7b2ac6818f57078c1087def2c187a208 165 SUPERFAMILY SSF142433 3 161 6.41E-60 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS21585 7b2ac6818f57078c1087def2c187a208 165 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 13 158 2.1E-64 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS21585 7b2ac6818f57078c1087def2c187a208 165 Pfam PF02464 Competence-damaged protein 8 160 9.3E-61 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS17695 39c82c525f38b7e3f0c48df0992fd26b 292 SUPERFAMILY SSF51556 3 291 2.54E-97 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS17695 39c82c525f38b7e3f0c48df0992fd26b 292 Pfam PF02126 Phosphotriesterase family 1 292 2.8E-141 T 10-03-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 RG49_RS17695 39c82c525f38b7e3f0c48df0992fd26b 292 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 7 15 - T 10-03-2017 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 RG49_RS17695 39c82c525f38b7e3f0c48df0992fd26b 292 PIRSF PIRSF016839 1 292 1.5E-132 T 10-03-2017 RG49_RS17695 39c82c525f38b7e3f0c48df0992fd26b 292 Gene3D G3DSA:3.20.20.140 2 292 5.9E-112 T 10-03-2017 RG49_RS01960 be648286af472ff8f3c164034187c47e 342 Gene3D G3DSA:3.40.50.2300 179 325 4.2E-36 T 10-03-2017 RG49_RS01960 be648286af472ff8f3c164034187c47e 342 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 65 341 1.7E-101 T 10-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain RG49_RS01960 be648286af472ff8f3c164034187c47e 342 SMART SM00354 6 76 2.9E-33 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS01960 be648286af472ff8f3c164034187c47e 342 Gene3D G3DSA:1.10.260.40 7 58 2.8E-22 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS01960 be648286af472ff8f3c164034187c47e 342 SUPERFAMILY SSF53822 63 338 6.23E-52 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS01960 be648286af472ff8f3c164034187c47e 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 9.0E-19 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS01960 be648286af472ff8f3c164034187c47e 342 SUPERFAMILY SSF47413 5 64 3.38E-16 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS01960 be648286af472ff8f3c164034187c47e 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 10-03-2017 RG49_RS01960 be648286af472ff8f3c164034187c47e 342 Gene3D G3DSA:3.40.50.2300 59 178 2.1E-35 T 10-03-2017 RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 2.4E-18 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 SMART SM00862 156 232 3.7E-15 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 SUPERFAMILY SSF52172 2 126 2.85E-36 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 SUPERFAMILY SSF46894 136 234 7.65E-22 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 Pfam PF00072 Response regulator receiver domain 6 113 8.3E-27 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 SMART SM00448 4 114 6.3E-38 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 Gene3D G3DSA:3.40.50.2300 2 123 1.8E-35 T 10-03-2017 RG49_RS11900 1917eff55d421295934a3e3ab9e8c178 238 Gene3D G3DSA:1.10.10.10 135 233 1.7E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00735 3182c2e590e2a982200fbc51cfe0daa7 76 Gene3D G3DSA:1.10.1110.10 1 76 3.9E-43 T 10-03-2017 IPR011325 DNA polymerase III-theta, core, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS00735 3182c2e590e2a982200fbc51cfe0daa7 76 SUPERFAMILY SSF46575 1 76 3.27E-35 T 10-03-2017 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 RG49_RS00735 3182c2e590e2a982200fbc51cfe0daa7 76 ProDom PD057609 DNA POLYMERASE THETA SUBUNIT TRANSFERASE III NUCLEOTIDYLTRANSFERASE III DNA-DIRECTED REPLICATION 1 76 3.0E-38 T 10-03-2017 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 RG49_RS00735 3182c2e590e2a982200fbc51cfe0daa7 76 Pfam PF06440 DNA polymerase III, theta subunit 4 71 4.5E-38 T 10-03-2017 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 RG49_RS23710 4e61f4990888ff483eea44f8c378b922 485 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 475 6.7E-150 T 10-03-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 RG49_RS23710 4e61f4990888ff483eea44f8c378b922 485 Pfam PF00361 Proton-conducting membrane transporter 122 420 1.1E-91 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23710 4e61f4990888ff483eea44f8c378b922 485 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 475 17.865 T 10-03-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 RG49_RS22795 18f7f6b826d0c97fef4671b3e2fa2ea8 232 Gene3D G3DSA:3.40.50.1820 7 206 2.1E-32 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS22795 18f7f6b826d0c97fef4671b3e2fa2ea8 232 SUPERFAMILY SSF53474 5 205 4.61E-31 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS22795 18f7f6b826d0c97fef4671b3e2fa2ea8 232 Pfam PF02230 Phospholipase/Carboxylesterase 4 209 1.3E-56 T 10-03-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82693 135 182 4.13E-27 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82693 274 330 4.13E-27 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1049 0.0 T 10-03-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82714 182 271 5.1E-20 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 Gene3D G3DSA:3.30.70.1430 569 671 1.2E-41 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 623 637 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 554 571 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 2.4E-115 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1030 0.0 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 Gene3D G3DSA:3.30.2090.10 724 812 1.3E-27 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 Gene3D G3DSA:3.30.2090.10 181 275 6.5E-24 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82693 38 132 4.88E-28 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 Gene3D G3DSA:3.30.70.1430 38 140 2.0E-36 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 Gene3D G3DSA:1.10.3850.10 817 1031 3.9E-56 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 Gene3D G3DSA:1.10.3850.10 278 498 3.6E-60 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82866 809 1033 9.29E-45 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82693 567 671 2.25E-33 T 10-03-2017 RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82714 725 812 2.49E-22 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS08795 c564a138f040b7ce63fb3db8488183e1 1049 SUPERFAMILY SSF82866 296 497 1.7E-48 T 10-03-2017 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 ProSitePatterns PS00099 Thiolases active site. 368 381 - T 10-03-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 10-03-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 Gene3D G3DSA:3.40.47.10 143 183 9.0E-58 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 Gene3D G3DSA:3.40.47.10 268 386 9.0E-58 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 PIRSF PIRSF000429 1 387 7.2E-130 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 Pfam PF00108 Thiolase, N-terminal domain 4 254 9.8E-86 T 10-03-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 10-03-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 Gene3D G3DSA:3.40.47.10 184 267 5.7E-64 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 Gene3D G3DSA:3.40.47.10 4 126 5.7E-64 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 3 387 6.7E-244 T 10-03-2017 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 SUPERFAMILY SSF53901 262 386 8.07E-43 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 Pfam PF02803 Thiolase, C-terminal domain 261 386 1.3E-49 T 10-03-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 SUPERFAMILY SSF53901 1 259 1.2E-77 T 10-03-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 Hamap MF_01620 3-ketoacyl-CoA thiolase [fadA]. 1 387 61.757 T 10-03-2017 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 RG49_RS14965 4c1e921f643d6dd26bce3be0fd008021 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 385 6.2E-145 T 10-03-2017 IPR002155 Thiolase GO:0008152|GO:0016747 RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF05593 RHS Repeat 425 463 7.9E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF05593 RHS Repeat 939 984 3.3E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF05593 RHS Repeat 489 511 1.7E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF05593 RHS Repeat 535 568 5.4E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF05593 RHS Repeat 361 391 2.0E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF05593 RHS Repeat 637 674 2.0E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF05593 RHS Repeat 575 611 7.9E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1170 1246 1.1E-23 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 Pfam PF03527 RHS protein 1143 1180 1.2E-13 T 10-03-2017 IPR001826 RHS protein RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 343 377 0.0012 T 10-03-2017 IPR006530 YD repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 575 612 1.3E-7 T 10-03-2017 IPR006530 YD repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 451 482 0.0028 T 10-03-2017 IPR006530 YD repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 409 444 1.5E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 489 511 6.3E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 678 6.8E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 PRINTS PR00394 RHS protein signature 1192 1212 9.0E-56 T 10-03-2017 IPR001826 RHS protein RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 PRINTS PR00394 RHS protein signature 1215 1234 9.0E-56 T 10-03-2017 IPR001826 RHS protein RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 PRINTS PR00394 RHS protein signature 1099 1118 9.0E-56 T 10-03-2017 IPR001826 RHS protein RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 PRINTS PR00394 RHS protein signature 1137 1157 9.0E-56 T 10-03-2017 IPR001826 RHS protein RG49_RS16495 7ffc2213c9d7d45067c6f8620bb0082c 1246 PRINTS PR00394 RHS protein signature 1168 1183 9.0E-56 T 10-03-2017 IPR001826 RHS protein RG49_RS14230 fdb0d509fcabda888f4573fac395de0b 316 PIRSF PIRSF000545 1 316 6.6E-150 T 10-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 RG49_RS14230 fdb0d509fcabda888f4573fac395de0b 316 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 10 316 3.3E-183 T 10-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 RG49_RS14230 fdb0d509fcabda888f4573fac395de0b 316 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 90 244 2.7E-14 T 10-03-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 RG49_RS14230 fdb0d509fcabda888f4573fac395de0b 316 Hamap MF_00215 Pantothenate kinase [coaA]. 1 316 191.287 T 10-03-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 RG49_RS14230 fdb0d509fcabda888f4573fac395de0b 316 Gene3D G3DSA:3.40.50.300 10 316 3.2E-112 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14230 fdb0d509fcabda888f4573fac395de0b 316 SUPERFAMILY SSF52540 10 315 1.49E-79 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20340 03e4f03a46cb65c9918753f279ec093e 200 Gene3D G3DSA:3.40.50.10420 13 199 4.9E-61 T 10-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain RG49_RS20340 03e4f03a46cb65c9918753f279ec093e 200 SUPERFAMILY SSF100950 12 200 4.46E-57 T 10-03-2017 RG49_RS20340 03e4f03a46cb65c9918753f279ec093e 200 PIRSF PIRSF006806 9 197 8.1E-37 T 10-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase RG49_RS20340 03e4f03a46cb65c9918753f279ec093e 200 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 13 194 1.4E-53 T 10-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase RG49_RS20340 03e4f03a46cb65c9918753f279ec093e 200 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 13 194 2.9E-45 T 10-03-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 Gene3D G3DSA:3.10.50.40 151 215 1.3E-9 T 10-03-2017 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 PIRSF PIRSF003095 1 432 1.3E-131 T 10-03-2017 IPR005215 Trigger factor GO:0015031 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 Gene3D G3DSA:3.30.70.1050 1 117 1.4E-39 T 10-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 Hamap MF_00303 Trigger factor [tig]. 1 418 22.209 T 10-03-2017 IPR005215 Trigger factor GO:0015031 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 262 412 8.6E-41 T 10-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 SUPERFAMILY SSF102735 1 131 5.62E-39 T 10-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 SUPERFAMILY SSF54534 97 241 2.16E-37 T 10-03-2017 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 2.0E-41 T 10-03-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 TIGRFAM TIGR00115 tig: trigger factor 13 412 1.1E-143 T 10-03-2017 IPR005215 Trigger factor GO:0015031 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 SUPERFAMILY SSF109998 248 429 1.09E-47 T 10-03-2017 IPR027304 Trigger factor/SurA domain RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 236 2.6E-14 T 10-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 RG49_RS08940 be175fae90c64d4e251742b3a98a8abe 432 Gene3D G3DSA:1.10.3120.10 216 388 1.4E-62 T 10-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 RG49_RS08810 44e440bb09de08f4df2a54e54e6ed7f1 183 SMART SM01266 5 59 2.4E-21 T 10-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 RG49_RS08810 44e440bb09de08f4df2a54e54e6ed7f1 183 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 138 166 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS08810 44e440bb09de08f4df2a54e54e6ed7f1 183 Gene3D G3DSA:2.160.10.10 2 183 1.3E-62 T 10-03-2017 RG49_RS08810 44e440bb09de08f4df2a54e54e6ed7f1 183 Pfam PF12464 Maltose acetyltransferase 7 57 3.1E-16 T 10-03-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 RG49_RS08810 44e440bb09de08f4df2a54e54e6ed7f1 183 SUPERFAMILY SSF51161 2 182 3.47E-55 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS08810 44e440bb09de08f4df2a54e54e6ed7f1 183 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 129 164 4.3E-11 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS08810 44e440bb09de08f4df2a54e54e6ed7f1 183 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 92 109 0.0041 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 Gene3D G3DSA:2.60.120.260 2 180 3.4E-58 T 10-03-2017 IPR008979 Galactose-binding domain-like RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 274 593 2.6E-111 T 10-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 Pfam PF00703 Glycosyl hydrolases family 2 184 272 5.7E-8 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 Gene3D G3DSA:2.60.40.320 182 273 4.0E-27 T 10-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 SUPERFAMILY SSF49785 1 180 9.07E-58 T 10-03-2017 IPR008979 Galactose-binding domain-like RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 324 349 - T 10-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 399 413 - T 10-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 PRINTS PR00132 Glycosyl hydrolase family 2 signature 91 106 1.3E-17 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 PRINTS PR00132 Glycosyl hydrolase family 2 signature 314 332 1.3E-17 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 PRINTS PR00132 Glycosyl hydrolase family 2 signature 399 414 1.3E-17 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 PRINTS PR00132 Glycosyl hydrolase family 2 signature 283 297 1.3E-17 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 PRINTS PR00132 Glycosyl hydrolase family 2 signature 498 513 1.3E-17 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 SUPERFAMILY SSF49303 182 273 3.45E-20 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 12 180 1.4E-66 T 10-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 SUPERFAMILY SSF51445 274 590 5.8E-85 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS01975 d10c0669b82883fed09d0df4dbf7fc5a 603 Gene3D G3DSA:3.20.20.80 275 589 1.3E-79 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS08375 ea61c9c3a5917d1b7290722baacef149 745 SUPERFAMILY SSF53448 71 414 6.75E-15 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS08375 ea61c9c3a5917d1b7290722baacef149 745 Pfam PF13632 Glycosyl transferase family group 2 165 381 2.1E-45 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS08375 ea61c9c3a5917d1b7290722baacef149 745 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 524 628 1.0E-17 T 10-03-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 RG49_RS08375 ea61c9c3a5917d1b7290722baacef149 745 SUPERFAMILY SSF160246 485 623 2.04E-25 T 10-03-2017 RG49_RS15075 f2045c7b67be2aa5ba327a83262764c1 206 Pfam PF01810 LysE type translocator 14 205 1.4E-57 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS15075 f2045c7b67be2aa5ba327a83262764c1 206 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 18 202 5.6E-71 T 10-03-2017 IPR004778 Homoserine/Threonine efflux protein GO:0016021 RG49_RS15075 f2045c7b67be2aa5ba327a83262764c1 206 PIRSF PIRSF006324 1 206 1.4E-41 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS10095 173b458ec9def66c2fcdfa702a20a2d5 233 Pfam PF08220 DeoR-like helix-turn-helix domain 14 50 1.5E-5 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS10095 173b458ec9def66c2fcdfa702a20a2d5 233 Pfam PF13280 WYL domain 129 197 9.2E-9 T 10-03-2017 IPR026881 WYL domain RG49_RS10095 173b458ec9def66c2fcdfa702a20a2d5 233 ProSitePatterns PS00894 DeoR-type HTH domain signature. 14 48 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS10095 173b458ec9def66c2fcdfa702a20a2d5 233 Gene3D G3DSA:1.10.10.10 8 48 7.0E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00545 20f0d08bb72b944a84e127f4cc0d366b 248 Gene3D G3DSA:3.20.20.380 1 244 1.3E-93 T 10-03-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 RG49_RS00545 20f0d08bb72b944a84e127f4cc0d366b 248 Pfam PF03932 CutC family 3 200 1.7E-85 T 10-03-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 RG49_RS00545 20f0d08bb72b944a84e127f4cc0d366b 248 SUPERFAMILY SSF110395 3 245 2.75E-77 T 10-03-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 RG49_RS00545 20f0d08bb72b944a84e127f4cc0d366b 248 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 2 243 39.031 T 10-03-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 Pfam PF04851 Type III restriction enzyme, res subunit 169 326 1.6E-43 T 10-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 Pfam PF08463 EcoEI R protein C-terminal 648 803 9.5E-27 T 10-03-2017 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 Gene3D G3DSA:3.40.50.300 166 337 1.9E-35 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 SUPERFAMILY SSF52540 153 365 2.38E-36 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 Gene3D G3DSA:3.40.50.300 404 530 4.2E-10 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 SMART SM00487 166 361 6.3E-23 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 34 119 2.3E-9 T 10-03-2017 IPR029464 Type I restriction enzyme R protein, N-terminal domain RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 SUPERFAMILY SSF52540 396 537 4.22E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 SUPERFAMILY SSF52540 280 285 4.22E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 SUPERFAMILY SSF52540 190 226 4.22E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12260 47653f8d8a3e591ed204a8a260ed9f62 810 Pfam PF00271 Helicase conserved C-terminal domain 412 526 4.5E-7 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 233 7.2E-21 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 Gene3D G3DSA:1.10.10.10 138 235 7.5E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 SMART SM00448 2 112 5.0E-30 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 SUPERFAMILY SSF46894 139 234 1.5E-25 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 SUPERFAMILY SSF52172 2 120 1.08E-29 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 Gene3D G3DSA:3.40.50.2300 2 137 2.0E-29 T 10-03-2017 RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 Pfam PF00072 Response regulator receiver domain 4 112 5.3E-20 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS02020 d2bb197bf93306a063ee18864155420c 239 SMART SM00862 157 233 2.0E-19 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 Pfam PF00005 ABC transporter 293 436 8.6E-27 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 Pfam PF00005 ABC transporter 28 175 7.0E-25 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 SMART SM00382 301 558 2.1E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 SMART SM00382 37 225 0.04 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 SUPERFAMILY SSF52540 276 498 1.08E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 Gene3D G3DSA:3.40.50.300 268 500 2.9E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 Gene3D G3DSA:3.40.50.300 14 241 8.2E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 Pfam PF12698 ABC-2 family transporter protein 569 903 4.4E-38 T 10-03-2017 RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 SUPERFAMILY SSF52540 15 239 2.87E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17135 d11ebfcb6625fe69047f51e45549311a 911 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 8.2E-70 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PIRSF PIRSF000350 1 447 6.9E-88 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 SUPERFAMILY SSF51905 1 365 2.88E-56 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 Gene3D G3DSA:3.50.50.60 3 143 9.6E-45 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 449 2.7E-35 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 Gene3D G3DSA:3.50.50.60 146 246 7.9E-31 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 7.2E-66 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 Gene3D G3DSA:3.50.50.60 247 333 3.9E-26 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 10-03-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 SUPERFAMILY SSF55424 336 450 8.08E-37 T 10-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 Gene3D G3DSA:3.30.390.30 338 450 9.3E-45 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 450 6.3E-218 T 10-03-2017 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 4.9E-28 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 4.9E-28 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 4.9E-28 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.9E-28 T 10-03-2017 RG49_RS17050 41bb97b7d2b88142daea346187d8a91d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 4.9E-28 T 10-03-2017 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 462 479 - T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 SUPERFAMILY SSF55604 449 523 1.44E-18 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 410 509 4.8E-32 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 2 523 1.1E-289 T 10-03-2017 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 60 358 8.6E-95 T 10-03-2017 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 Gene3D G3DSA:3.30.1360.60 448 524 2.4E-24 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 Pfam PF02378 Phosphotransferase system, EIIC 10 346 6.0E-74 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS15810 38d39ac079bee40a13b71ef9cd2fad43 538 Pfam PF00367 phosphotransferase system, EIIB 453 482 1.0E-11 T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 328 515 4.0E-68 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 Gene3D G3DSA:1.10.287.950 284 488 3.9E-63 T 10-03-2017 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 Gene3D G3DSA:1.20.120.30 35 181 1.3E-62 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 SMART SM00319 44 182 4.1E-70 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 ProSitePatterns PS00538 Bacterial chemotaxis sensory transducers signature. 294 316 - T 10-03-2017 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 Pfam PF02203 Tar ligand binding domain homologue 1 176 5.0E-58 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 SUPERFAMILY SSF58104 236 520 1.09E-75 T 10-03-2017 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 2.1E-92 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 60 75 2.1E-92 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 2.1E-92 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 2.1E-92 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 191 211 2.1E-92 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 2.1E-92 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 2.1E-92 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 SUPERFAMILY SSF47170 25 181 2.49E-52 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 SMART SM00304 216 268 6.7E-13 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 SMART SM00283 269 516 9.0E-96 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS12180 86b21d916bb4927f63f043f8a5931bf6 551 Pfam PF00672 HAMP domain 196 263 7.1E-15 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 Pfam PF00183 Hsp90 protein 211 622 6.6E-125 T 10-03-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 Gene3D G3DSA:3.30.565.10 5 238 5.7E-84 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 SUPERFAMILY SSF110942 510 623 1.7E-34 T 10-03-2017 RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PRINTS PR00775 90kDa heat shock protein signature 120 142 2.3E-64 T 10-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PRINTS PR00775 90kDa heat shock protein signature 26 48 2.3E-64 T 10-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PRINTS PR00775 90kDa heat shock protein signature 75 92 2.3E-64 T 10-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PRINTS PR00775 90kDa heat shock protein signature 190 208 2.3E-64 T 10-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PRINTS PR00775 90kDa heat shock protein signature 93 110 2.3E-64 T 10-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PRINTS PR00775 90kDa heat shock protein signature 172 189 2.3E-64 T 10-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PRINTS PR00775 90kDa heat shock protein signature 5 25 2.3E-64 T 10-03-2017 IPR020575 Heat shock protein Hsp90, N-terminal RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 SUPERFAMILY SSF55874 4 213 1.22E-67 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 SUPERFAMILY SSF54211 230 485 1.44E-103 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 623 33.248 T 10-03-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 25 34 - T 10-03-2017 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 PIRSF PIRSF002583 1 624 1.5E-220 T 10-03-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 182 2.2E-15 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08730 46be049f6f54705e4e4750ffc9649e9d 624 SMART SM00387 27 184 1.1E-12 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS00065 a3d55915cdf8c9490b7d10a2ee42fe87 39 Gene3D G3DSA:2.40.160.10 1 39 8.2E-5 T 10-03-2017 IPR023614 Porin domain RG49_RS00065 a3d55915cdf8c9490b7d10a2ee42fe87 39 Pfam PF00267 Gram-negative porin 1 39 3.8E-7 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS00065 a3d55915cdf8c9490b7d10a2ee42fe87 39 SUPERFAMILY SSF56935 1 39 4.03E-5 T 10-03-2017 RG49_RS06485 95bfed85dd31f0fa6388f8ee93f842fb 317 Gene3D G3DSA:1.10.3720.10 26 306 5.3E-51 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06485 95bfed85dd31f0fa6388f8ee93f842fb 317 SUPERFAMILY SSF161098 27 308 7.98E-57 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06485 95bfed85dd31f0fa6388f8ee93f842fb 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 313 6.1E-24 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS05250 3ea45bf91377644637e3d465a8ecb854 232 PRINTS PR01008 Flagellar L-ring protein signature 73 85 1.8E-36 T 10-03-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 RG49_RS05250 3ea45bf91377644637e3d465a8ecb854 232 PRINTS PR01008 Flagellar L-ring protein signature 172 188 1.8E-36 T 10-03-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 RG49_RS05250 3ea45bf91377644637e3d465a8ecb854 232 PRINTS PR01008 Flagellar L-ring protein signature 146 161 1.8E-36 T 10-03-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 RG49_RS05250 3ea45bf91377644637e3d465a8ecb854 232 PRINTS PR01008 Flagellar L-ring protein signature 193 207 1.8E-36 T 10-03-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 RG49_RS05250 3ea45bf91377644637e3d465a8ecb854 232 PRINTS PR01008 Flagellar L-ring protein signature 209 223 1.8E-36 T 10-03-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 RG49_RS05250 3ea45bf91377644637e3d465a8ecb854 232 Pfam PF02107 Flagellar L-ring protein 47 231 1.7E-60 T 10-03-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 RG49_RS05250 3ea45bf91377644637e3d465a8ecb854 232 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 230 28.065 T 10-03-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 RG49_RS04535 04a2ee16744fe2b52290f8ce9c2ab392 76 Pfam PF06150 ChaB 9 75 9.6E-28 T 10-03-2017 IPR009317 ChaB RG49_RS04535 04a2ee16744fe2b52290f8ce9c2ab392 76 SUPERFAMILY SSF140376 2 75 9.29E-29 T 10-03-2017 RG49_RS01870 d76a3d3965661b7f68059d8501c00579 201 Gene3D G3DSA:3.40.30.10 1 88 1.4E-25 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS01870 d76a3d3965661b7f68059d8501c00579 201 Pfam PF13409 Glutathione S-transferase, N-terminal domain 14 75 3.5E-9 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS01870 d76a3d3965661b7f68059d8501c00579 201 SUPERFAMILY SSF52833 1 79 1.97E-18 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS01870 d76a3d3965661b7f68059d8501c00579 201 SUPERFAMILY SSF47616 83 199 4.37E-30 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS01870 d76a3d3965661b7f68059d8501c00579 201 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 189 8.0E-18 T 10-03-2017 IPR004046 Glutathione S-transferase, C-terminal RG49_RS01870 d76a3d3965661b7f68059d8501c00579 201 Gene3D G3DSA:1.20.1050.10 89 188 1.0E-40 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS07920 416e6b328d255b232fc4d25449f34574 105 SUPERFAMILY SSF81301 4 105 1.59E-37 T 10-03-2017 RG49_RS07920 416e6b328d255b232fc4d25449f34574 105 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 7.0E-29 T 10-03-2017 RG49_RS07920 416e6b328d255b232fc4d25449f34574 105 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.806 T 10-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS RG49_RS07920 416e6b328d255b232fc4d25449f34574 105 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 4.4E-38 T 10-03-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS RG49_RS07920 416e6b328d255b232fc4d25449f34574 105 Gene3D G3DSA:3.30.460.10 4 105 4.1E-38 T 10-03-2017 RG49_RS16925 cd4c3a179a1c67021eea0851a8b5cb0d 323 SUPERFAMILY SSF46785 28 108 3.71E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16925 cd4c3a179a1c67021eea0851a8b5cb0d 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 29 86 5.5E-18 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS16925 cd4c3a179a1c67021eea0851a8b5cb0d 323 Gene3D G3DSA:1.10.10.10 28 107 4.6E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16925 cd4c3a179a1c67021eea0851a8b5cb0d 323 Gene3D G3DSA:3.40.190.10 116 215 6.2E-28 T 10-03-2017 RG49_RS16925 cd4c3a179a1c67021eea0851a8b5cb0d 323 Pfam PF03466 LysR substrate binding domain 113 316 5.6E-43 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS16925 cd4c3a179a1c67021eea0851a8b5cb0d 323 SUPERFAMILY SSF53850 114 321 1.38E-45 T 10-03-2017 RG49_RS03425 9deb2dc4c08c65338389af1e760b8c04 262 Gene3D G3DSA:3.90.226.10 2 202 6.5E-68 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS03425 9deb2dc4c08c65338389af1e760b8c04 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 261 3.1E-62 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS03425 9deb2dc4c08c65338389af1e760b8c04 262 SUPERFAMILY SSF52096 1 261 1.01E-85 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS03425 9deb2dc4c08c65338389af1e760b8c04 262 Gene3D G3DSA:1.10.12.10 204 262 9.1E-20 T 10-03-2017 IPR014748 Crontonase, C-terminal RG49_RS03425 9deb2dc4c08c65338389af1e760b8c04 262 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 5 262 5.8E-146 T 10-03-2017 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 RG49_RS03910 0b4df7c8be0817a72aece9635c70217f 242 Pfam PF00246 Zinc carboxypeptidase 43 157 5.0E-13 T 10-03-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 RG49_RS03910 0b4df7c8be0817a72aece9635c70217f 242 SUPERFAMILY SSF53187 129 234 1.59E-33 T 10-03-2017 RG49_RS03910 0b4df7c8be0817a72aece9635c70217f 242 SUPERFAMILY SSF53187 16 102 1.59E-33 T 10-03-2017 RG49_RS03910 0b4df7c8be0817a72aece9635c70217f 242 Gene3D G3DSA:3.40.630.10 18 223 5.8E-44 T 10-03-2017 RG49_RS11995 ec9d968bc40d42032cb52ebca1d57d5c 239 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 10-03-2017 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS11995 ec9d968bc40d42032cb52ebca1d57d5c 239 SUPERFAMILY SSF53167 3 234 2.36E-94 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS11995 ec9d968bc40d42032cb52ebca1d57d5c 239 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 234 5.1E-128 T 10-03-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 RG49_RS11995 ec9d968bc40d42032cb52ebca1d57d5c 239 Pfam PF01048 Phosphorylase superfamily 15 218 2.1E-39 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS11995 ec9d968bc40d42032cb52ebca1d57d5c 239 Gene3D G3DSA:3.40.50.1580 10 233 1.2E-83 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS11995 ec9d968bc40d42032cb52ebca1d57d5c 239 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 2 235 52.534 T 10-03-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 TIGRFAM TIGR02183 GRXA: glutaredoxin, GrxA family 3 84 1.3E-44 T 10-03-2017 IPR011902 Glutaredoxin, GrxA GO:0009055|GO:0015035|GO:0045454 RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 ProSitePatterns PS00195 Glutaredoxin active site. 5 20 - T 10-03-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 PRINTS PR00160 Glutaredoxin signature 3 21 1.1E-10 T 10-03-2017 IPR014025 Glutaredoxin subgroup RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 PRINTS PR00160 Glutaredoxin signature 66 79 1.1E-10 T 10-03-2017 IPR014025 Glutaredoxin subgroup RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 PRINTS PR00160 Glutaredoxin signature 52 65 1.1E-10 T 10-03-2017 IPR014025 Glutaredoxin subgroup RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 Gene3D G3DSA:3.40.30.10 2 82 8.7E-27 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 Pfam PF00462 Glutaredoxin 4 69 6.3E-17 T 10-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 RG49_RS06525 ae2b2a4fa755d5685227f4a885f51a20 85 SUPERFAMILY SSF52833 2 82 2.84E-21 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.4E-20 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 SUPERFAMILY SSF46785 2 85 1.62E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.2E-10 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.2E-10 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.2E-10 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 Gene3D G3DSA:1.10.10.10 2 82 1.6E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 SUPERFAMILY SSF53850 89 270 1.81E-15 T 10-03-2017 RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 Hamap MF_01233 HTH-type transcriptional regulator HdfR [hdfR]. 1 278 54.904 T 10-03-2017 IPR020890 Transcription regulator HTH, HdfR GO:0003677|GO:0003700|GO:0045892 RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 Pfam PF03466 LysR substrate binding domain 87 270 8.6E-14 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 Gene3D G3DSA:3.40.190.10 89 177 1.1E-7 T 10-03-2017 RG49_RS15395 e4498100732f0ecfbdd3785ff1cf2341 279 Gene3D G3DSA:3.40.190.10 211 222 1.1E-7 T 10-03-2017 RG49_RS12880 52b83be2a2bf7bf9e7fdddc4afb04133 690 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 63 1.4E-8 T 10-03-2017 RG49_RS12880 52b83be2a2bf7bf9e7fdddc4afb04133 690 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 440 462 1.4E-8 T 10-03-2017 RG49_RS12880 52b83be2a2bf7bf9e7fdddc4afb04133 690 Pfam PF00890 FAD binding domain 43 475 1.5E-29 T 10-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS12880 52b83be2a2bf7bf9e7fdddc4afb04133 690 Gene3D G3DSA:3.50.50.60 433 487 1.2E-36 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS12880 52b83be2a2bf7bf9e7fdddc4afb04133 690 Gene3D G3DSA:3.50.50.60 41 279 1.2E-36 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS12880 52b83be2a2bf7bf9e7fdddc4afb04133 690 SUPERFAMILY SSF51905 39 276 4.72E-31 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS12880 52b83be2a2bf7bf9e7fdddc4afb04133 690 SUPERFAMILY SSF51905 441 492 4.72E-31 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 4.3E-5 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 4.3E-5 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 SUPERFAMILY SSF55136 122 288 2.04E-57 T 10-03-2017 IPR011256 Regulatory factor, effector binding domain RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 SUPERFAMILY SSF46689 6 55 1.04E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 Gene3D G3DSA:3.20.80.10 123 289 7.3E-65 T 10-03-2017 IPR011256 Regulatory factor, effector binding domain RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 SMART SM00871 126 288 1.6E-13 T 10-03-2017 IPR010499 Bacterial transcription activator, effector binding RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 SUPERFAMILY SSF46689 57 108 4.44E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 Gene3D G3DSA:1.10.10.60 3 57 5.7E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 Pfam PF06445 GyrI-like small molecule binding domain 127 288 8.0E-22 T 10-03-2017 IPR029442 GyrI-like small molecule binding domain RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 55 100 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 Gene3D G3DSA:1.10.10.60 58 119 1.8E-23 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 Pfam PF12833 Helix-turn-helix domain 27 105 1.3E-19 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS11925 bc065e0b1cf7ff5683bfa06a591c9fc5 289 SMART SM00342 21 104 3.6E-31 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 Gene3D G3DSA:1.20.58.370 2 95 1.4E-39 T 10-03-2017 RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 Gene3D G3DSA:3.10.650.10 196 269 8.1E-40 T 10-03-2017 RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 Gene3D G3DSA:1.10.3720.10 275 510 5.4E-63 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 SUPERFAMILY SSF160964 15 260 1.44E-90 T 10-03-2017 RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 Gene3D G3DSA:2.40.430.10 118 195 1.5E-39 T 10-03-2017 RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 SUPERFAMILY SSF161098 261 503 1.23E-60 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 Pfam PF14785 Maltose transport system permease protein MalF P2 domain 100 260 4.7E-59 T 10-03-2017 IPR029345 Maltose transport system permease protein MalF, P2 domain RG49_RS13885 faf622c364636b73271ca43697fcd8d1 514 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 298 501 6.0E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 SUPERFAMILY SSF46689 249 300 5.82E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 SUPERFAMILY SSF51215 71 180 3.53E-5 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 Pfam PF14525 AraC-binding-like domain 12 185 4.9E-23 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 Gene3D G3DSA:1.10.10.60 249 300 3.2E-17 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 281 9.6E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 297 9.6E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 Pfam PF12833 Helix-turn-helix domain 219 298 1.0E-20 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 Gene3D G3DSA:1.10.10.60 191 248 5.6E-8 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03475 01f3bbc978ac0482330c1c3a42916e5d 301 SMART SM00342 213 297 8.0E-27 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 Pfam PF00857 Isochorismatase family 32 205 3.7E-38 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 Gene3D G3DSA:3.40.50.850 1 229 1.6E-77 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 SUPERFAMILY SSF47336 209 280 3.93E-8 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 PIRSF PIRSF001111 1 285 1.4E-132 T 10-03-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 SUPERFAMILY SSF52499 1 209 1.31E-64 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 Gene3D G3DSA:1.10.1200.10 230 282 1.3E-5 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 Pfam PF00550 Phosphopantetheine attachment site 217 276 1.7E-7 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 PRINTS PR01398 Isochorismatase signature 2 14 2.7E-51 T 10-03-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 PRINTS PR01398 Isochorismatase signature 168 186 2.7E-51 T 10-03-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 PRINTS PR01398 Isochorismatase signature 112 134 2.7E-51 T 10-03-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 PRINTS PR01398 Isochorismatase signature 80 99 2.7E-51 T 10-03-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 PRINTS PR01398 Isochorismatase signature 186 203 2.7E-51 T 10-03-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 RG49_RS08155 d86cbc59170ea19583ca269d1d94c5c1 285 PRINTS PR01398 Isochorismatase signature 63 80 2.7E-51 T 10-03-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 RG49_RS09360 29e7442445eb04f15ea53a600a2d2409 39 Pfam PF12035 Protein of unknown function (DUF3521) 1 28 8.0E-8 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS16320 12d3d05862c436a455609c62328231ec 341 SUPERFAMILY SSF50129 1 173 8.67E-55 T 10-03-2017 IPR011032 GroES-like RG49_RS16320 12d3d05862c436a455609c62328231ec 341 SUPERFAMILY SSF51735 141 305 1.5E-37 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16320 12d3d05862c436a455609c62328231ec 341 Gene3D G3DSA:3.40.50.720 173 287 2.7E-35 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16320 12d3d05862c436a455609c62328231ec 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS16320 12d3d05862c436a455609c62328231ec 341 Pfam PF00107 Zinc-binding dehydrogenase 174 301 1.9E-27 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS16320 12d3d05862c436a455609c62328231ec 341 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 61.281 T 10-03-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 RG49_RS16320 12d3d05862c436a455609c62328231ec 341 Gene3D G3DSA:3.90.180.10 1 172 2.7E-52 T 10-03-2017 IPR011032 GroES-like RG49_RS16320 12d3d05862c436a455609c62328231ec 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 1.2E-31 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS16320 12d3d05862c436a455609c62328231ec 341 SMART SM00829 12 338 1.3E-5 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS16320 12d3d05862c436a455609c62328231ec 341 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 3 340 4.6E-192 T 10-03-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 RG49_RS15530 75e7ada38e15a23c696fd31fc2f9e66b 156 SUPERFAMILY SSF81573 63 121 1.7E-15 T 10-03-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain RG49_RS15530 75e7ada38e15a23c696fd31fc2f9e66b 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 2.1E-61 T 10-03-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 RG49_RS15530 75e7ada38e15a23c696fd31fc2f9e66b 156 Gene3D G3DSA:1.20.5.620 62 122 6.2E-26 T 10-03-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain RG49_RS15530 75e7ada38e15a23c696fd31fc2f9e66b 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 156 13.12 T 10-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 RG49_RS15530 75e7ada38e15a23c696fd31fc2f9e66b 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 4.8E-40 T 10-03-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 RG49_RS07535 05e067501990bf5de6856bd0ddad9363 218 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 1.5E-107 T 10-03-2017 IPR010016 KipI family RG49_RS07535 05e067501990bf5de6856bd0ddad9363 218 Pfam PF02682 Allophanate hydrolase subunit 1 6 202 2.8E-70 T 10-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D RG49_RS07535 05e067501990bf5de6856bd0ddad9363 218 SMART SM00796 4 202 1.3E-94 T 10-03-2017 IPR003833 Carboxyltransferase domain, subdomain C and D RG49_RS07535 05e067501990bf5de6856bd0ddad9363 218 SUPERFAMILY SSF50891 88 214 7.59E-47 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS07535 05e067501990bf5de6856bd0ddad9363 218 Gene3D G3DSA:2.40.100.10 88 213 1.4E-52 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS07535 05e067501990bf5de6856bd0ddad9363 218 SUPERFAMILY SSF160467 5 93 1.57E-9 T 10-03-2017 RG49_RS07535 05e067501990bf5de6856bd0ddad9363 218 Gene3D G3DSA:3.30.1360.40 6 79 2.4E-8 T 10-03-2017 IPR024946 Arginine repressor C-terminal-like domain RG49_RS05070 d201ebc06b3dbbf11a78039edcfa180e 320 SUPERFAMILY SSF141523 101 240 3.14E-28 T 10-03-2017 RG49_RS05070 d201ebc06b3dbbf11a78039edcfa180e 320 SMART SM00257 45 91 2.9E-7 T 10-03-2017 IPR018392 LysM domain RG49_RS05070 d201ebc06b3dbbf11a78039edcfa180e 320 Gene3D G3DSA:3.10.350.10 53 91 1.2E-6 T 10-03-2017 IPR018392 LysM domain RG49_RS05070 d201ebc06b3dbbf11a78039edcfa180e 320 Pfam PF01476 LysM domain 47 91 8.9E-7 T 10-03-2017 IPR018392 LysM domain RG49_RS05070 d201ebc06b3dbbf11a78039edcfa180e 320 Pfam PF03734 L,D-transpeptidase catalytic domain 103 240 1.9E-19 T 10-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 RG49_RS05070 d201ebc06b3dbbf11a78039edcfa180e 320 Gene3D G3DSA:2.40.440.10 96 242 3.3E-34 T 10-03-2017 RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 SUPERFAMILY SSF55073 230 387 2.04E-22 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 SUPERFAMILY SSF141868 403 642 2.48E-35 T 10-03-2017 IPR001633 EAL domain RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 Gene3D G3DSA:3.30.70.270 227 391 4.5E-25 T 10-03-2017 RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 SMART SM00052 395 635 4.0E-62 T 10-03-2017 IPR001633 EAL domain RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 222 381 1.0E-11 T 10-03-2017 IPR000160 GGDEF domain RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 Pfam PF00563 EAL domain 403 628 7.1E-37 T 10-03-2017 IPR001633 EAL domain RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 Gene3D G3DSA:3.20.20.450 398 638 2.1E-34 T 10-03-2017 IPR001633 EAL domain RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 Pfam PF17157 Gammaproteobacterial periplasmic sensor domain 34 130 8.1E-33 T 10-03-2017 IPR033423 Gammaproteobacterial periplasmic sensor domain GAPES4 RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 Pfam PF00990 Diguanylate cyclase, GGDEF domain 224 380 1.4E-32 T 10-03-2017 IPR000160 GGDEF domain RG49_RS18350 5f0729a801c84209f14f33e4a3e340f8 646 SMART SM00267 213 385 4.1E-43 T 10-03-2017 IPR000160 GGDEF domain RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 SUPERFAMILY SSF48019 212 335 1.87E-36 T 10-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 Gene3D G3DSA:1.10.8.60 143 222 1.5E-38 T 10-03-2017 RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 Gene3D G3DSA:1.20.272.20 223 341 1.3E-52 T 10-03-2017 RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 Gene3D G3DSA:3.40.50.300 1 140 1.1E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 Pfam PF06144 DNA polymerase III, delta subunit 21 190 2.4E-47 T 10-03-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 SUPERFAMILY SSF52540 1 210 3.15E-55 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 18 332 1.3E-107 T 10-03-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 RG49_RS07905 4e457f49a23a0bb5c1524113b121e870 343 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 214 338 1.7E-73 T 10-03-2017 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS24615 3a5efd80dc8fbaa7a0757ad4a1d6d1d5 369 SUPERFAMILY SSF52540 108 355 1.89E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24615 3a5efd80dc8fbaa7a0757ad4a1d6d1d5 369 Gene3D G3DSA:3.40.50.300 97 349 1.2E-105 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24615 3a5efd80dc8fbaa7a0757ad4a1d6d1d5 369 SUPERFAMILY SSF117916 15 85 1.05E-5 T 10-03-2017 RG49_RS24615 3a5efd80dc8fbaa7a0757ad4a1d6d1d5 369 ProSitePatterns PS01215 Mrp family signature. 213 229 - T 10-03-2017 IPR000808 Mrp, conserved site GO:0005524 RG49_RS24615 3a5efd80dc8fbaa7a0757ad4a1d6d1d5 369 Hamap MF_02040 Iron-sulfur cluster carrier protein. 101 350 37.76 T 10-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein RG49_RS24615 3a5efd80dc8fbaa7a0757ad4a1d6d1d5 369 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 106 349 1.6E-101 T 10-03-2017 IPR019591 Mrp/NBP35 ATP-binding protein RG49_RS20810 a3ccce98e16a7b4406c29eb60bdc85f9 278 SUPERFAMILY SSF51182 2 262 3.14E-109 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS20810 a3ccce98e16a7b4406c29eb60bdc85f9 278 Gene3D G3DSA:2.60.120.520 20 133 9.3E-57 T 10-03-2017 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 RG49_RS20810 a3ccce98e16a7b4406c29eb60bdc85f9 278 PIRSF PIRSF006625 1 278 1.5E-133 T 10-03-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 RG49_RS20810 a3ccce98e16a7b4406c29eb60bdc85f9 278 Gene3D G3DSA:2.60.120.500 134 278 3.7E-79 T 10-03-2017 IPR027447 5-keto-4-deoxyuronate isomerase, C-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 RG49_RS20810 a3ccce98e16a7b4406c29eb60bdc85f9 278 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 278 57.023 T 10-03-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 RG49_RS20810 a3ccce98e16a7b4406c29eb60bdc85f9 278 Pfam PF04962 KduI/IolB family 31 273 1.8E-42 T 10-03-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 SUPERFAMILY SSF46689 57 106 1.12E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 Pfam PF12833 Helix-turn-helix domain 27 106 6.0E-24 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 Gene3D G3DSA:1.10.10.60 58 106 1.9E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 SUPERFAMILY SSF46689 4 56 2.09E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 SMART SM00342 21 104 3.9E-34 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 Gene3D G3DSA:1.10.10.60 1 57 1.4E-22 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 1.8E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS13710 777af84098a120aab0a33c6cb4269d71 107 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 1.8E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF03527 RHS protein 1143 1180 5.4E-15 T 10-03-2017 IPR001826 RHS protein RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 575 612 3.5E-9 T 10-03-2017 IPR006530 YD repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 678 7.8E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 451 482 0.0031 T 10-03-2017 IPR006530 YD repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 596 627 4.8E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 409 444 4.3E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 473 508 4.9E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF05593 RHS Repeat 575 611 4.3E-9 T 10-03-2017 IPR031325 RHS repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF05593 RHS Repeat 637 674 2.6E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF05593 RHS Repeat 361 391 2.3E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF05593 RHS Repeat 425 463 1.9E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF05593 RHS Repeat 535 568 4.7E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF05593 RHS Repeat 489 511 3.4E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 Pfam PF05593 RHS Repeat 939 984 3.8E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1170 1247 4.0E-23 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 PRINTS PR00394 RHS protein signature 1168 1183 1.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 PRINTS PR00394 RHS protein signature 1215 1234 1.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 PRINTS PR00394 RHS protein signature 1099 1118 1.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 PRINTS PR00394 RHS protein signature 1137 1157 1.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS07590 4e4fc814386c2ad1e8a370228edc18ad 1397 PRINTS PR00394 RHS protein signature 1192 1212 1.6E-55 T 10-03-2017 IPR001826 RHS protein RG49_RS20800 2e8772e4139a5c9333f3cfb4f88bd647 409 Pfam PF03222 Tryptophan/tyrosine permease family 16 379 4.7E-11 T 10-03-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 RG49_RS19440 39bd625a041496ff3c68ac71e6e433e5 310 Gene3D G3DSA:1.10.10.10 9 91 1.1E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19440 39bd625a041496ff3c68ac71e6e433e5 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.5E-15 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19440 39bd625a041496ff3c68ac71e6e433e5 310 Gene3D G3DSA:3.40.190.10 181 265 1.5E-22 T 10-03-2017 RG49_RS19440 39bd625a041496ff3c68ac71e6e433e5 310 SUPERFAMILY SSF46785 9 115 1.36E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19440 39bd625a041496ff3c68ac71e6e433e5 310 Gene3D G3DSA:3.40.190.10 97 180 8.1E-20 T 10-03-2017 RG49_RS19440 39bd625a041496ff3c68ac71e6e433e5 310 Pfam PF03466 LysR substrate binding domain 93 296 2.8E-35 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS19440 39bd625a041496ff3c68ac71e6e433e5 310 SUPERFAMILY SSF53850 94 299 7.24E-39 T 10-03-2017 RG49_RS07875 d599e4be9020e59908063c4f9282e41c 475 SUPERFAMILY SSF46565 2 47 2.75E-6 T 10-03-2017 IPR001623 DnaJ domain RG49_RS07875 d599e4be9020e59908063c4f9282e41c 475 Gene3D G3DSA:1.10.287.110 2 47 9.3E-5 T 10-03-2017 IPR001623 DnaJ domain RG49_RS07875 d599e4be9020e59908063c4f9282e41c 475 SMART SM00271 2 58 4.3E-4 T 10-03-2017 IPR001623 DnaJ domain RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 0.0 T 10-03-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 1.1E-97 T 10-03-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 SUPERFAMILY SSF52540 313 587 5.4E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 Hamap MF_01973 Lon protease [lon]. 11 772 72.577 T 10-03-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 SUPERFAMILY SSF54211 595 771 1.1E-59 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 201 5.8E-43 T 10-03-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 1.9E-17 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 7.1E-57 T 10-03-2017 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 7.1E-57 T 10-03-2017 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 7.1E-57 T 10-03-2017 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 7.1E-57 T 10-03-2017 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 7.1E-57 T 10-03-2017 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 Gene3D G3DSA:3.30.230.10 590 771 3.1E-77 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 Gene3D G3DSA:1.10.8.60 500 584 4.4E-33 T 10-03-2017 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 PIRSF PIRSF001174 1 775 0.0 T 10-03-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 Gene3D G3DSA:3.40.50.300 310 499 3.4E-33 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 10-03-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 SMART SM00464 10 202 3.9E-88 T 10-03-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 SUPERFAMILY SSF88697 10 201 4.22E-52 T 10-03-2017 IPR015947 PUA-like domain RG49_RS08925 ce48f6ed2f5ed052d5b4c46400f3e1d6 784 SMART SM00382 348 492 4.9E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17185 35e173d071fe7b3a1f9fcc71f85b73bd 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 308 1.0E-44 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17185 35e173d071fe7b3a1f9fcc71f85b73bd 314 Gene3D G3DSA:1.10.3720.10 89 304 2.4E-25 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17185 35e173d071fe7b3a1f9fcc71f85b73bd 314 SUPERFAMILY SSF161098 94 308 1.2E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17185 35e173d071fe7b3a1f9fcc71f85b73bd 314 TIGRFAM TIGR02789 nickel_nikB: nickel ABC transporter, permease subunit NikB 1 314 3.0E-170 T 10-03-2017 IPR014156 Nickel ABC transporter, permease subunit NikB GO:0015099|GO:0035444 RG49_RS03355 be2d224193ffe564e32c8b68a89592d8 266 Pfam PF02698 DUF218 domain 40 173 8.0E-16 T 10-03-2017 IPR003848 Domain of unknown function DUF218 RG49_RS03355 be2d224193ffe564e32c8b68a89592d8 266 Gene3D G3DSA:3.40.50.620 31 180 2.9E-56 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS20980 7a00ae8c22df3914bbbf3c359488f179 365 SMART SM00925 125 257 2.4E-70 T 10-03-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 RG49_RS20980 7a00ae8c22df3914bbbf3c359488f179 365 Gene3D G3DSA:2.40.40.10 76 163 1.8E-14 T 10-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain RG49_RS20980 7a00ae8c22df3914bbbf3c359488f179 365 Gene3D G3DSA:2.40.40.10 166 353 4.0E-47 T 10-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain RG49_RS20980 7a00ae8c22df3914bbbf3c359488f179 365 SUPERFAMILY SSF50685 25 353 1.85E-116 T 10-03-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain RG49_RS20980 7a00ae8c22df3914bbbf3c359488f179 365 Pfam PF06725 3D domain 277 354 3.5E-25 T 10-03-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 RG49_RS20980 7a00ae8c22df3914bbbf3c359488f179 365 Pfam PF03562 MltA specific insert domain 93 257 5.4E-41 T 10-03-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 674 876 3.5E-38 T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.6E-77 T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 6.5E-40 T 10-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.3E-63 T 10-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.3E-63 T 10-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.3E-63 T 10-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.3E-63 T 10-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.3E-63 T 10-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.3E-63 T 10-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.3E-63 T 10-03-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SUPERFAMILY SSF56059 128 401 1.06E-109 T 10-03-2017 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SMART SM00851 956 1042 7.0E-30 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SUPERFAMILY SSF52440 1 127 2.73E-50 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SUPERFAMILY SSF56059 674 934 1.61E-104 T 10-03-2017 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:3.30.1490.20 687 745 1.3E-25 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:3.30.470.20 200 399 8.5E-76 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:3.30.470.20 746 933 1.1E-81 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SUPERFAMILY SSF52335 938 1071 2.09E-35 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1063 13.191 T 10-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1068 13.369 T 10-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Pfam PF02142 MGS-like domain 957 1041 3.1E-18 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:3.40.50.20 3 108 1.4E-46 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:3.30.1490.20 141 199 8.7E-28 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 839 846 - T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:3.40.50.20 539 663 2.8E-62 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1053 0.0 T 10-03-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 710 724 - T 10-03-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:1.10.1030.10 400 538 4.9E-52 T 10-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SMART SM01096 424 547 3.0E-73 T 10-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 Gene3D G3DSA:3.40.50.1380 939 1072 2.9E-39 T 10-03-2017 IPR011607 Methylglyoxal synthase-like domain RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SUPERFAMILY SSF48108 396 554 1.57E-52 T 10-03-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11705 402e23b4b3143eb7603293562af65d68 1073 SUPERFAMILY SSF52440 557 676 9.93E-50 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS06185 0f7490d45baddf54e20237a41e546b97 227 Gene3D G3DSA:3.40.50.300 6 221 2.4E-77 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06185 0f7490d45baddf54e20237a41e546b97 227 Pfam PF02224 Cytidylate kinase 8 221 4.1E-85 T 10-03-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 RG49_RS06185 0f7490d45baddf54e20237a41e546b97 227 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 219 1.5E-97 T 10-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 RG49_RS06185 0f7490d45baddf54e20237a41e546b97 227 SUPERFAMILY SSF52540 6 224 5.98E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06185 0f7490d45baddf54e20237a41e546b97 227 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 34.523 T 10-03-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 Pfam PF07687 Peptidase dimerisation domain 175 282 3.6E-25 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 Gene3D G3DSA:3.40.630.10 316 373 1.5E-75 T 10-03-2017 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 Gene3D G3DSA:3.40.630.10 5 187 1.5E-75 T 10-03-2017 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 Pfam PF01546 Peptidase family M20/M25/M40 62 371 1.8E-43 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 6 373 2.7E-173 T 10-03-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 10-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 3 375 52.316 T 10-03-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 97 136 - T 10-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 SUPERFAMILY SSF53187 292 373 2.17E-65 T 10-03-2017 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 SUPERFAMILY SSF53187 5 178 2.17E-65 T 10-03-2017 RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 Gene3D G3DSA:3.30.70.360 188 288 1.4E-34 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS22805 21197779d49f3d578c4b0baa72c7e2f9 375 SUPERFAMILY SSF55031 179 286 2.84E-29 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS11435 ca864650b3b215c619e7ca7958675e39 588 Pfam PF03717 Penicillin-binding Protein dimerisation domain 70 220 2.4E-21 T 10-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 RG49_RS11435 ca864650b3b215c619e7ca7958675e39 588 SUPERFAMILY SSF56519 63 233 1.18E-46 T 10-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 RG49_RS11435 ca864650b3b215c619e7ca7958675e39 588 SUPERFAMILY SSF56601 235 563 1.93E-86 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS11435 ca864650b3b215c619e7ca7958675e39 588 Pfam PF00905 Penicillin binding protein transpeptidase domain 260 554 3.4E-82 T 10-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 RG49_RS11435 ca864650b3b215c619e7ca7958675e39 588 Gene3D G3DSA:3.40.710.10 242 560 7.5E-85 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS11435 ca864650b3b215c619e7ca7958675e39 588 Gene3D G3DSA:3.90.1310.10 142 241 4.6E-33 T 10-03-2017 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 42.679 T 10-03-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 Pfam PF00682 HMGL-like 4 273 8.1E-106 T 10-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 499 1.6E-35 T 10-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 10-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 SMART SM00917 369 500 7.5E-37 T 10-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 Gene3D G3DSA:3.20.20.70 1 347 8.4E-142 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 SUPERFAMILY SSF51569 1 290 3.85E-97 T 10-03-2017 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 497 3.1E-260 T 10-03-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 SUPERFAMILY SSF110921 391 499 1.11E-25 T 10-03-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 RG49_RS11490 2e7ad6989e4f507866d7138706f23ec1 523 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 10-03-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 SMART SM00319 44 180 3.9E-43 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 SUPERFAMILY SSF47170 39 178 1.83E-47 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 SMART SM00304 214 266 1.5E-11 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 Pfam PF02203 Tar ligand binding domain homologue 1 169 1.5E-44 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 Gene3D G3DSA:1.20.120.30 36 179 4.3E-52 T 10-03-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 Gene3D G3DSA:1.10.287.950 282 486 1.1E-64 T 10-03-2017 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 SUPERFAMILY SSF58104 235 522 2.09E-76 T 10-03-2017 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 3.7E-91 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 3.7E-91 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 60 75 3.7E-91 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 3.7E-91 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 189 209 3.7E-91 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 3.7E-91 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 3.7E-91 T 10-03-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 Pfam PF00672 HAMP domain 194 262 1.1E-13 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 ProSitePatterns PS00538 Bacterial chemotaxis sensory transducers signature. 292 314 - T 10-03-2017 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 513 2.3E-68 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS00480 ff05f294e6bf7a816da63051f614c5d8 553 SMART SM00283 267 514 7.0E-96 T 10-03-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 169 181 - T 10-03-2017 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 Pfam PF00145 C-5 cytosine-specific DNA methylase 87 448 2.7E-76 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 Gene3D G3DSA:3.40.50.150 87 309 5.9E-53 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 Gene3D G3DSA:3.90.120.10 310 438 4.0E-29 T 10-03-2017 RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 432 450 - T 10-03-2017 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 89 450 2.8E-105 T 10-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 SUPERFAMILY SSF53335 87 450 9.28E-80 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 88 104 2.2E-15 T 10-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 271 284 2.2E-15 T 10-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 RG49_RS00100 6e0c616111480557ecb8cb0fa883ba88 472 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 217 231 2.2E-15 T 10-03-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 RG49_RS22950 b353cedc91ac4357fcffac05436368c3 289 SMART SM00646 118 273 4.0E-66 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS22950 b353cedc91ac4357fcffac05436368c3 289 Gene3D G3DSA:3.40.630.40 201 277 4.0E-59 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS22950 b353cedc91ac4357fcffac05436368c3 289 Gene3D G3DSA:3.40.630.40 57 153 4.0E-59 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS22950 b353cedc91ac4357fcffac05436368c3 289 SUPERFAMILY SSF53187 200 277 7.85E-55 T 10-03-2017 RG49_RS22950 b353cedc91ac4357fcffac05436368c3 289 SUPERFAMILY SSF53187 57 152 7.85E-55 T 10-03-2017 RG49_RS22950 b353cedc91ac4357fcffac05436368c3 289 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 59 273 1.6E-51 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS17505 90dd4e3546b019c08092479057c66d2b 256 Gene3D G3DSA:3.40.50.1820 3 251 8.7E-57 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS17505 90dd4e3546b019c08092479057c66d2b 256 Pfam PF00561 alpha/beta hydrolase fold 15 242 3.3E-32 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS17505 90dd4e3546b019c08092479057c66d2b 256 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 4 254 47.567 T 10-03-2017 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 RG49_RS17505 90dd4e3546b019c08092479057c66d2b 256 SUPERFAMILY SSF53474 3 250 1.77E-47 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS17505 90dd4e3546b019c08092479057c66d2b 256 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 10 252 9.4E-123 T 10-03-2017 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 SUPERFAMILY SSF52540 187 421 1.65E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 Hamap MF_01314 Anaerobic nitric oxide reductase transcription regulator NorR [norR]. 1 503 61.349 T 10-03-2017 IPR023944 Anaerobic nitric oxide reductase transcription regulator GO:0003700|GO:0006355 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 SMART SM00382 207 350 2.0E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 Pfam PF01590 GAF domain 23 154 2.0E-9 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 273 288 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 Gene3D G3DSA:1.10.10.60 411 502 7.7E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 Gene3D G3DSA:3.30.450.40 7 167 2.1E-16 T 10-03-2017 IPR029016 GAF domain-like RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 211 224 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 Gene3D G3DSA:1.10.8.60 360 410 5.5E-18 T 10-03-2017 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 SUPERFAMILY SSF46689 451 502 6.27E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 SUPERFAMILY SSF55781 22 170 1.37E-17 T 10-03-2017 IPR029016 GAF domain-like RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 Gene3D G3DSA:3.40.50.300 184 359 4.7E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 Pfam PF00158 Sigma-54 interaction domain 187 353 1.3E-66 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 SMART SM00065 20 167 1.3E-20 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS21540 63f92f773c1520e906b7854d4c930c91 504 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 400 409 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS02605 f27d652a5e1da40754052365306a6c70 119 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 1 114 6.0E-53 T 10-03-2017 IPR020378 Protein of unknown function DUF4186 RG49_RS02605 f27d652a5e1da40754052365306a6c70 119 Pfam PF13811 Domain of unknown function (DUF4186) 7 112 2.6E-51 T 10-03-2017 IPR020378 Protein of unknown function DUF4186 RG49_RS01040 359cc2ab9a43705c447cacc1a5617997 148 Pfam PF04284 Protein of unknown function (DUF441) 7 145 7.4E-46 T 10-03-2017 IPR007382 Uncharacterised protein family UPF0756, transmembrame RG49_RS01040 359cc2ab9a43705c447cacc1a5617997 148 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 1 130 1.0E-41 T 10-03-2017 IPR007382 Uncharacterised protein family UPF0756, transmembrame RG49_RS01040 359cc2ab9a43705c447cacc1a5617997 148 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 148 18.673 T 10-03-2017 IPR007382 Uncharacterised protein family UPF0756, transmembrame RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 23 39 - T 10-03-2017 IPR013061 Tryptophan/tryrosine permease, conserved site RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 13 396 1.7E-155 T 10-03-2017 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 43 62 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 294 313 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 349 368 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 194 216 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 233 252 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 16 39 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 328 346 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 88 108 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 PRINTS PR00166 Aromatic amino acid permease signature 154 174 8.0E-102 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS15670 30dd661bb8143b1a3c58868294235093 415 Pfam PF03222 Tryptophan/tyrosine permease family 7 403 2.3E-149 T 10-03-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 4.1E-96 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 497 3.7E-231 T 10-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 10-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 60.299 T 10-03-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 10-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 PIRSF PIRSF000538 4 502 2.9E-178 T 10-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 SUPERFAMILY SSF53067 256 498 1.73E-87 T 10-03-2017 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 SUPERFAMILY SSF53067 5 256 1.76E-96 T 10-03-2017 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 451 5.3E-62 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 Gene3D G3DSA:3.30.420.40 2 254 1.1E-108 T 10-03-2017 RG49_RS14495 5209eac880717d0df7e3e72045ac99b9 502 Gene3D G3DSA:3.30.420.40 256 498 4.5E-105 T 10-03-2017 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 Pfam PF02378 Phosphotransferase system, EIIC 19 361 1.5E-87 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 TIGRFAM TIGR02004 PTS-IIBC-malX: PTS system, maltose and glucose-specific IIBC component 8 525 1.7E-257 T 10-03-2017 IPR011301 PTS system, maltose/glucose-specific IIBC component GO:0008982|GO:0009401 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 420 511 3.1E-27 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 70 372 5.1E-99 T 10-03-2017 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 SUPERFAMILY SSF55604 454 525 2.88E-21 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 Pfam PF00367 phosphotransferase system, EIIB 455 486 2.2E-16 T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 Gene3D G3DSA:3.30.1360.60 454 525 4.3E-27 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS01955 afd3eb819942c977bb330b327dde2fa5 530 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 464 481 - T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS08705 07e4d7e681d4d66b23d6e92af2c1f0d3 558 SUPERFAMILY SSF51735 418 549 2.57E-29 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08705 07e4d7e681d4d66b23d6e92af2c1f0d3 558 Pfam PF02254 TrkA-N domain 421 534 3.6E-25 T 10-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 RG49_RS08705 07e4d7e681d4d66b23d6e92af2c1f0d3 558 Pfam PF00999 Sodium/hydrogen exchanger family 13 384 6.0E-77 T 10-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 RG49_RS08705 07e4d7e681d4d66b23d6e92af2c1f0d3 558 Gene3D G3DSA:3.40.50.720 414 548 2.9E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08705 07e4d7e681d4d66b23d6e92af2c1f0d3 558 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 15 294 8.8E-77 T 10-03-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 SUPERFAMILY SSF46557 15 90 2.49E-28 T 10-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 Gene3D G3DSA:1.10.287.180 13 87 2.9E-27 T 10-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 Pfam PF03449 Transcription elongation factor, N-terminal 18 86 3.2E-27 T 10-03-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 Hamap MF_00105 Transcription elongation factor GreA [greA]. 14 166 29.031 T 10-03-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 SUPERFAMILY SSF54534 92 167 4.32E-20 T 10-03-2017 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 Gene3D G3DSA:3.10.50.30 88 167 8.3E-27 T 10-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 Hamap MF_00930 Transcription elongation factor GreB [greB]. 13 168 54.298 T 10-03-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 PIRSF PIRSF006092 11 169 2.0E-46 T 10-03-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 93 167 1.5E-22 T 10-03-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 14 169 5.0E-89 T 10-03-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 131 147 - T 10-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 RG49_RS17545 a7ed4e7cdb76c8462124b0d7fe96e72b 170 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 29 60 - T 10-03-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 RG49_RS09535 e70ae54fffaa6d941a02bbbf8257d731 472 Gene3D G3DSA:1.10.10.660 95 155 1.7E-36 T 10-03-2017 IPR024033 Uncharacterised domain, YlbE RG49_RS09535 e70ae54fffaa6d941a02bbbf8257d731 472 Pfam PF06545 Protein of unknown function (DUF1116) 143 357 1.9E-89 T 10-03-2017 IPR009499 Protein of unknown function DUF1116 RG49_RS09535 e70ae54fffaa6d941a02bbbf8257d731 472 Gene3D G3DSA:3.90.1700.10 305 470 9.3E-78 T 10-03-2017 RG49_RS09535 e70ae54fffaa6d941a02bbbf8257d731 472 Gene3D G3DSA:3.90.1710.10 156 303 2.5E-73 T 10-03-2017 RG49_RS12325 81c67bd5b520df0b802414eeeb35cfcb 85 Pfam PF11823 Protein of unknown function (DUF3343) 4 56 7.0E-11 T 10-03-2017 IPR021778 Protein of unknown function DUF3343 RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 Pfam PF14220 Domain of unknown function (DUF4329) 1281 1392 6.4E-26 T 10-03-2017 IPR025479 Domain of unknown function DUF4329 RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 Pfam PF05593 RHS Repeat 535 565 3.6E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 Pfam PF05593 RHS Repeat 617 652 6.8E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 Pfam PF05593 RHS Repeat 575 611 1.3E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 Pfam PF03527 RHS protein 1145 1182 2.7E-16 T 10-03-2017 IPR001826 RHS protein RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 575 614 3.1E-11 T 10-03-2017 IPR006530 YD repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 677 3.0E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 468 508 4.9E-7 T 10-03-2017 IPR006530 YD repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 536 566 6.5E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 596 627 7.9E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1172 1249 2.4E-23 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 PRINTS PR00394 RHS protein signature 1101 1120 3.0E-50 T 10-03-2017 IPR001826 RHS protein RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 PRINTS PR00394 RHS protein signature 1139 1159 3.0E-50 T 10-03-2017 IPR001826 RHS protein RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 PRINTS PR00394 RHS protein signature 1217 1236 3.0E-50 T 10-03-2017 IPR001826 RHS protein RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 PRINTS PR00394 RHS protein signature 1194 1214 3.0E-50 T 10-03-2017 IPR001826 RHS protein RG49_RS25290 0e2c5030f72300c08ae472c633bee948 1413 PRINTS PR00394 RHS protein signature 1170 1185 3.0E-50 T 10-03-2017 IPR001826 RHS protein RG49_RS14455 5c777df608588d438894558893bfb5cc 341 Gene3D G3DSA:3.40.50.2300 174 338 8.3E-68 T 10-03-2017 RG49_RS14455 5c777df608588d438894558893bfb5cc 341 Gene3D G3DSA:1.10.260.40 10 65 1.4E-20 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS14455 5c777df608588d438894558893bfb5cc 341 Pfam PF13377 Periplasmic binding protein-like domain 176 337 2.5E-44 T 10-03-2017 RG49_RS14455 5c777df608588d438894558893bfb5cc 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 10-03-2017 RG49_RS14455 5c777df608588d438894558893bfb5cc 341 SUPERFAMILY SSF53822 68 338 4.91E-92 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS14455 5c777df608588d438894558893bfb5cc 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 1.6E-19 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS14455 5c777df608588d438894558893bfb5cc 341 SMART SM00354 9 79 1.1E-30 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS14455 5c777df608588d438894558893bfb5cc 341 Gene3D G3DSA:3.40.50.2300 66 173 7.8E-31 T 10-03-2017 RG49_RS14455 5c777df608588d438894558893bfb5cc 341 SUPERFAMILY SSF47413 10 67 7.88E-15 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS19125 994df575ca9a00e2f723808a842887e5 329 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 49 62 - T 10-03-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 RG49_RS19125 994df575ca9a00e2f723808a842887e5 329 SUPERFAMILY SSF53686 11 321 1.31E-93 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS19125 994df575ca9a00e2f723808a842887e5 329 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 28 323 7.0E-116 T 10-03-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 RG49_RS19125 994df575ca9a00e2f723808a842887e5 329 Gene3D G3DSA:3.40.50.1100 76 323 1.5E-76 T 10-03-2017 RG49_RS19125 994df575ca9a00e2f723808a842887e5 329 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 312 4.9E-78 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 Gene3D G3DSA:3.40.50.1260 5 174 2.1E-64 T 10-03-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PIRSF PIRSF000724 1 387 1.3E-134 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 SUPERFAMILY SSF53748 3 383 8.01E-145 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 Pfam PF00162 Phosphoglycerate kinase 6 373 3.1E-138 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 1.6E-82 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 Gene3D G3DSA:3.40.50.1270 175 371 5.6E-81 T 10-03-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 10-03-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS20260 aff29f0997aaf745c2d595a81522ee3f 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 383 39.19 T 10-03-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS01335 b0a7142fddbbed4a3af1f7b0f993e0ca 249 Pfam PF04794 YdjC-like protein 5 237 7.7E-58 T 10-03-2017 IPR006879 Chitooligosaccharide deacetylase ChbG-like RG49_RS01335 b0a7142fddbbed4a3af1f7b0f993e0ca 249 SUPERFAMILY SSF88713 1 249 8.89E-74 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS01335 b0a7142fddbbed4a3af1f7b0f993e0ca 249 Gene3D G3DSA:3.20.20.370 1 249 1.1E-79 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS01335 b0a7142fddbbed4a3af1f7b0f993e0ca 249 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG]. 3 246 40.588 T 10-03-2017 IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria GO:0000272|GO:0016811 RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 Gene3D G3DSA:3.90.550.10 344 386 5.9E-78 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 Gene3D G3DSA:3.90.550.10 22 301 5.9E-78 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 17 423 52.657 T 10-03-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 26 45 - T 10-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 211 221 - T 10-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 113 121 - T 10-03-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 SUPERFAMILY SSF51161 313 411 2.65E-18 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 SUPERFAMILY SSF53448 378 393 3.55E-77 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 SUPERFAMILY SSF53448 20 294 3.55E-77 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 21 397 5.5E-157 T 10-03-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 RG49_RS17420 05cd82970d4201684be6b75f265cec03 431 Pfam PF00483 Nucleotidyl transferase 22 291 3.1E-69 T 10-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 Gene3D G3DSA:3.40.1410.10 62 232 3.3E-48 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 SUPERFAMILY SSF46785 2 69 4.55E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 Pfam PF07702 UTRA domain 87 224 5.0E-30 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 SUPERFAMILY SSF64288 53 232 7.54E-45 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 SMART SM00866 86 225 1.9E-33 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 Gene3D G3DSA:1.10.10.10 2 61 3.8E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 SMART SM00345 6 65 3.6E-22 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 2.5E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 2.5E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15805 fcc0eb97f3b7f64b10af74d7f79c97a2 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 64 4.5E-21 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 SUPERFAMILY SSF51905 2 175 5.41E-41 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 SUPERFAMILY SSF51905 280 403 5.41E-41 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 SUPERFAMILY SSF54373 175 277 2.63E-17 T 10-03-2017 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 Gene3D G3DSA:3.50.50.60 4 232 2.3E-41 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 Pfam PF12831 FAD dependent oxidoreductase 6 150 8.5E-9 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.4E-7 T 10-03-2017 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 5.4E-7 T 10-03-2017 RG49_RS21220 30ce9333a91d8fa65e4c3cc3e0484661 423 Gene3D G3DSA:3.30.9.10 233 336 7.5E-6 T 10-03-2017 RG49_RS01720 ef335284e35e70dd99c1d2f096de2836 457 Hamap MF_00400 Multidrug resistance protein MdtK [mdtK]. 1 457 54.669 T 10-03-2017 IPR022913 Multidrug resistance protein MdtK RG49_RS01720 ef335284e35e70dd99c1d2f096de2836 457 Pfam PF01554 MatE 17 177 1.9E-41 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS01720 ef335284e35e70dd99c1d2f096de2836 457 Pfam PF01554 MatE 244 405 2.4E-38 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS01720 ef335284e35e70dd99c1d2f096de2836 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 422 7.2E-127 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS01720 ef335284e35e70dd99c1d2f096de2836 457 PIRSF PIRSF006603 4 453 3.7E-59 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS08650 a85c20e4084895da5745ff554a6991a9 310 Gene3D G3DSA:3.40.710.10 3 309 9.6E-119 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS08650 a85c20e4084895da5745ff554a6991a9 310 Hamap MF_00313 Glutaminase [glsA]. 3 308 43.764 T 10-03-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 RG49_RS08650 a85c20e4084895da5745ff554a6991a9 310 SUPERFAMILY SSF56601 3 309 1.99E-113 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS08650 a85c20e4084895da5745ff554a6991a9 310 TIGRFAM TIGR03814 Gln_ase: glutaminase A 8 308 7.2E-114 T 10-03-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 RG49_RS08650 a85c20e4084895da5745ff554a6991a9 310 Pfam PF04960 Glutaminase 24 308 1.3E-105 T 10-03-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 Pfam PF00267 Gram-negative porin 29 360 7.6E-153 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 312 328 - T 10-03-2017 IPR013793 Porin, Gram-negative type, conserved site RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00183 E.coli/Salmonella-type porin signature 153 175 1.2E-72 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00183 E.coli/Salmonella-type porin signature 24 40 1.2E-72 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00183 E.coli/Salmonella-type porin signature 53 71 1.2E-72 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00183 E.coli/Salmonella-type porin signature 98 120 1.2E-72 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00183 E.coli/Salmonella-type porin signature 268 287 1.2E-72 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00183 E.coli/Salmonella-type porin signature 239 256 1.2E-72 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 233 245 8.8E-20 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 54 65 8.8E-20 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 8.8E-20 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 155 166 8.8E-20 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 312 329 8.8E-20 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 SUPERFAMILY SSF56935 24 360 6.8E-87 T 10-03-2017 RG49_RS09840 3e6b485f055b0abc96b93f9e9978dbd0 360 Gene3D G3DSA:2.40.160.10 24 360 8.0E-108 T 10-03-2017 IPR023614 Porin domain RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 330 6.3E-118 T 10-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 142 163 3.1E-30 T 10-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 3.1E-30 T 10-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 195 205 3.1E-30 T 10-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 3.1E-30 T 10-03-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 SUPERFAMILY SSF52374 5 330 1.73E-98 T 10-03-2017 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 Gene3D G3DSA:1.10.240.10 206 324 1.3E-20 T 10-03-2017 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 Gene3D G3DSA:3.40.50.620 4 205 6.1E-90 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 Pfam PF00579 tRNA synthetases class I (W and Y) 3 285 4.1E-90 T 10-03-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 331 42.679 T 10-03-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 RG49_RS17665 96efecbb175fa71e17b4badca3f602a9 334 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 SUPERFAMILY SSF47384 244 328 6.28E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 SMART SM00387 371 482 1.7E-35 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 SUPERFAMILY SSF55874 316 479 8.51E-40 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 5.6E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 479 5.6E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 5.6E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 5.6E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 Gene3D G3DSA:1.10.287.130 251 322 1.6E-10 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 326 3.5E-11 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 Pfam PF00672 HAMP domain 191 256 8.3E-9 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 481 4.4E-20 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 SMART SM00388 261 327 3.7E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 SMART SM00304 207 260 4.3E-9 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 Gene3D G3DSA:3.30.565.10 331 479 5.8E-40 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08325 d64d2175b17bf1c1bb8e3271901f5e0f 482 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 9 479 2.2E-157 T 10-03-2017 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 RG49_RS18405 d936b4b87db42878256ba5cafe5cfafc 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.4E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS18405 d936b4b87db42878256ba5cafe5cfafc 309 Pfam PF03466 LysR substrate binding domain 90 290 8.3E-39 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS18405 d936b4b87db42878256ba5cafe5cfafc 309 Gene3D G3DSA:1.10.10.10 3 87 1.2E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS18405 d936b4b87db42878256ba5cafe5cfafc 309 SUPERFAMILY SSF46785 4 108 5.17E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS18405 d936b4b87db42878256ba5cafe5cfafc 309 Gene3D G3DSA:3.40.190.10 92 173 1.4E-8 T 10-03-2017 RG49_RS18405 d936b4b87db42878256ba5cafe5cfafc 309 Gene3D G3DSA:3.40.190.10 174 259 5.6E-17 T 10-03-2017 RG49_RS18405 d936b4b87db42878256ba5cafe5cfafc 309 SUPERFAMILY SSF53850 90 292 4.03E-39 T 10-03-2017 RG49_RS24135 9392c3b99b034008003e34155fa57fa3 205 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 198 1.2E-85 T 10-03-2017 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 RG49_RS24135 9392c3b99b034008003e34155fa57fa3 205 SMART SM00382 26 203 1.8E-6 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24135 9392c3b99b034008003e34155fa57fa3 205 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24135 9392c3b99b034008003e34155fa57fa3 205 Pfam PF00005 ABC transporter 19 154 5.2E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS24135 9392c3b99b034008003e34155fa57fa3 205 Gene3D G3DSA:3.40.50.300 2 189 4.7E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24135 9392c3b99b034008003e34155fa57fa3 205 SUPERFAMILY SSF52540 2 186 2.01E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10940 28147fa28f3d53579ba996ba4637440a 285 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 239 265 - T 10-03-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 RG49_RS10940 28147fa28f3d53579ba996ba4637440a 285 Pfam PF01148 Cytidylyltransferase family 4 278 5.7E-71 T 10-03-2017 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 SUPERFAMILY SSF53850 33 358 2.78E-55 T 10-03-2017 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 Pfam PF13416 Bacterial extracellular solute-binding protein 56 327 2.1E-25 T 10-03-2017 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 152 1.9E-6 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 276 295 1.9E-6 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 62 83 1.9E-6 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 Gene3D G3DSA:3.40.190.10 147 299 1.3E-28 T 10-03-2017 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 Gene3D G3DSA:3.40.190.10 300 327 5.3E-29 T 10-03-2017 RG49_RS03205 be40be0d6a6bf3ab8820e6453732f25e 381 Gene3D G3DSA:3.40.190.10 35 145 5.3E-29 T 10-03-2017 RG49_RS14645 0fbb4e4327a0778f49df12c491039489 274 TIGRFAM TIGR02624 rhamnu_1P_ald: rhamnulose-1-phosphate aldolase 1 272 9.8E-142 T 10-03-2017 IPR013447 Rhamnulose-1-phosphate aldolase GO:0008994|GO:0019301 KEGG: 00040+4.1.2.19|KEGG: 00051+4.1.2.19 RG49_RS14645 0fbb4e4327a0778f49df12c491039489 274 SUPERFAMILY SSF53639 1 271 9.81E-79 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS14645 0fbb4e4327a0778f49df12c491039489 274 SMART SM01007 11 239 5.0E-32 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS14645 0fbb4e4327a0778f49df12c491039489 274 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 238 8.0E-35 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS14645 0fbb4e4327a0778f49df12c491039489 274 Gene3D G3DSA:3.40.225.10 1 271 2.6E-110 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS14645 0fbb4e4327a0778f49df12c491039489 274 Hamap MF_00770 Rhamnulose-1-phosphate aldolase [rhaD]. 1 272 58.055 T 10-03-2017 IPR013447 Rhamnulose-1-phosphate aldolase GO:0008994|GO:0019301 KEGG: 00040+4.1.2.19|KEGG: 00051+4.1.2.19 RG49_RS14280 4e283760d8ea01febd28a43dd22d064c 366 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 299 328 - T 10-03-2017 IPR030390 RNA methyltransferase TrmA, active site RG49_RS14280 4e283760d8ea01febd28a43dd22d064c 366 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 10 365 1.1E-187 T 10-03-2017 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 RG49_RS14280 4e283760d8ea01febd28a43dd22d064c 366 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 348 358 - T 10-03-2017 IPR030391 RNA methyltransferase TrmA, conserved site RG49_RS14280 4e283760d8ea01febd28a43dd22d064c 366 Gene3D G3DSA:3.40.50.150 155 364 3.1E-44 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS14280 4e283760d8ea01febd28a43dd22d064c 366 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 366 42.811 T 10-03-2017 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 RG49_RS14280 4e283760d8ea01febd28a43dd22d064c 366 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 10 365 9.7E-187 T 10-03-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 RG49_RS14280 4e283760d8ea01febd28a43dd22d064c 366 SUPERFAMILY SSF53335 6 363 1.08E-53 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 Pfam PF12168 DNA polymerase III subunits tau domain IV DnaB-binding 417 498 1.1E-20 T 10-03-2017 IPR022001 DNA polymerase III subunit tau, DnaB-binding domain IV KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 SUPERFAMILY SSF52540 35 221 2.1E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 Gene3D G3DSA:1.20.272.10 243 361 5.6E-49 T 10-03-2017 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 Pfam PF13177 DNA polymerase III, delta subunit 20 178 4.0E-42 T 10-03-2017 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 500 640 8.3E-59 T 10-03-2017 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 361 2.9E-32 T 10-03-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 356 8.2E-134 T 10-03-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 SUPERFAMILY SSF48019 243 366 2.55E-36 T 10-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 SMART SM00382 37 178 1.1E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 Gene3D G3DSA:3.40.50.300 15 166 8.0E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.8E-5 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.8E-5 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS08745 3514bc6f19a5da6e368fab2fb2bcd3c4 643 Gene3D G3DSA:1.10.8.60 167 242 1.1E-33 T 10-03-2017 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 Gene3D G3DSA:2.30.40.10 376 460 1.4E-14 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 3 453 1.0E-203 T 10-03-2017 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 Gene3D G3DSA:2.30.40.10 2 68 4.4E-27 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 Gene3D G3DSA:3.20.20.140 69 375 7.2E-103 T 10-03-2017 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 Pfam PF01979 Amidohydrolase family 50 434 2.0E-21 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 SUPERFAMILY SSF51556 54 381 5.68E-95 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 SUPERFAMILY SSF51338 349 456 2.7E-36 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 SUPERFAMILY SSF51338 1 64 3.09E-14 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20545 8e555556cd550078de49eb63a2ec7ad4 461 Hamap MF_01644 D-phenylhydantoinase [hyuA]. 1 461 100.282 T 10-03-2017 IPR023766 D-phenylhydantoinase GO:0005737|GO:0006208|GO:0016812 RG49_RS00690 c1e3d41d2a392cbbdca3ca1af6cf7f7d 96 Gene3D G3DSA:1.10.10.710 20 86 8.7E-27 T 10-03-2017 IPR009813 Uncharacterised protein family YebG RG49_RS00690 c1e3d41d2a392cbbdca3ca1af6cf7f7d 96 Pfam PF07130 YebG protein 1 74 6.0E-34 T 10-03-2017 IPR009813 Uncharacterised protein family YebG RG49_RS19285 2ef2cd33abeccf0bc69fc339ac9673f7 378 SUPERFAMILY SSF53335 194 373 8.81E-29 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS19285 2ef2cd33abeccf0bc69fc339ac9673f7 378 Pfam PF05175 Methyltransferase small domain 199 370 9.9E-59 T 10-03-2017 IPR007848 Methyltransferase small domain GO:0008168 RG49_RS19285 2ef2cd33abeccf0bc69fc339ac9673f7 378 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 1 373 50.392 T 10-03-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS19285 2ef2cd33abeccf0bc69fc339ac9673f7 378 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 302 308 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS19285 2ef2cd33abeccf0bc69fc339ac9673f7 378 Gene3D G3DSA:3.40.50.150 192 373 2.6E-30 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS19285 2ef2cd33abeccf0bc69fc339ac9673f7 378 PIRSF PIRSF037565 1 374 5.1E-166 T 10-03-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 270 1.4E-112 T 10-03-2017 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 SUPERFAMILY SSF51735 102 268 3.81E-47 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 269 33.417 T 10-03-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 121 190 5.2E-10 T 10-03-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 Gene3D G3DSA:3.40.192.10 2 107 4.4E-38 T 10-03-2017 RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 Gene3D G3DSA:3.40.50.720 108 244 3.9E-51 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 SUPERFAMILY SSF53223 2 101 1.78E-32 T 10-03-2017 RG49_RS18195 21789729ea9a46ac1229042bf1736709 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 1.2E-23 T 10-03-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 RG49_RS01945 d44a2fd7d35146cf110895eb20e4d3bd 333 Hamap MF_00540 Adenosine deaminase [add]. 1 331 55.24 T 10-03-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 RG49_RS01945 d44a2fd7d35146cf110895eb20e4d3bd 333 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 274 280 - T 10-03-2017 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 RG49_RS01945 d44a2fd7d35146cf110895eb20e4d3bd 333 Gene3D G3DSA:3.20.20.140 5 332 2.4E-99 T 10-03-2017 RG49_RS01945 d44a2fd7d35146cf110895eb20e4d3bd 333 Pfam PF00962 Adenosine/AMP deaminase 6 328 5.0E-109 T 10-03-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 RG49_RS01945 d44a2fd7d35146cf110895eb20e4d3bd 333 SUPERFAMILY SSF51556 5 326 5.51E-78 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS01945 d44a2fd7d35146cf110895eb20e4d3bd 333 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 6 330 6.4E-110 T 10-03-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 Pfam PF00005 ABC transporter 17 156 2.0E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 Pfam PF03459 TOBE domain 290 350 1.8E-17 T 10-03-2017 IPR005116 Transport-associated OB, type 1 RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 2 350 2.8E-166 T 10-03-2017 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 288 351 9.0E-24 T 10-03-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 SUPERFAMILY SSF50331 234 350 7.23E-22 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 Gene3D G3DSA:2.40.50.100 277 348 1.4E-22 T 10-03-2017 RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 Gene3D G3DSA:3.40.50.300 17 218 2.8E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 SMART SM00382 23 206 4.2E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS07210 a6e8614a32fc93e74348ce170275822f 352 SUPERFAMILY SSF52540 7 219 1.28E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14285 2f6db36b7105d20f193c42038f4a3b07 119 ProDom PD076479 MEMBRANE INNER YIJD TRANSMEMBRANE Y0323 AAA SIMILAR A ACETYL-COENZYME VV0128 1 119 2.0E-64 T 10-03-2017 IPR009867 Protein of unknown function DUF1422 RG49_RS14285 2f6db36b7105d20f193c42038f4a3b07 119 Pfam PF07226 Protein of unknown function (DUF1422) 3 115 2.2E-54 T 10-03-2017 IPR009867 Protein of unknown function DUF1422 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 SUPERFAMILY SSF89550 6 263 7.65E-18 T 10-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 Pfam PF01336 OB-fold nucleic acid binding domain 1000 1072 2.0E-8 T 10-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 Pfam PF02811 PHP domain 8 171 6.5E-40 T 10-03-2017 IPR004013 PHP domain GO:0003824 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 Pfam PF14579 Helix-hairpin-helix motif 808 897 2.8E-25 T 10-03-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1031 0.0 T 10-03-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 Gene3D G3DSA:1.10.150.280 836 883 1.0E-5 T 10-03-2017 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 Gene3D G3DSA:3.20.20.140 6 257 1.7E-21 T 10-03-2017 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 Gene3D G3DSA:2.40.50.140 982 1078 7.6E-11 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 291 735 2.8E-179 T 10-03-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS10895 f950e4fc98ec91abd0b4b3ead1e6026b 1160 SMART SM00481 7 74 1.5E-26 T 10-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 RG49_RS22415 de6f99239b4941ac1360cd737b466eb9 162 SUPERFAMILY SSF46785 2 133 6.18E-36 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22415 de6f99239b4941ac1360cd737b466eb9 162 Pfam PF02082 Transcriptional regulator 1 83 2.7E-27 T 10-03-2017 IPR000944 Transcription regulator Rrf2-type RG49_RS22415 de6f99239b4941ac1360cd737b466eb9 162 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 1.9E-66 T 10-03-2017 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 RG49_RS22415 de6f99239b4941ac1360cd737b466eb9 162 Gene3D G3DSA:1.10.10.10 1 134 6.1E-31 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22415 de6f99239b4941ac1360cd737b466eb9 162 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 7.4E-47 T 10-03-2017 IPR000944 Transcription regulator Rrf2-type RG49_RS22415 de6f99239b4941ac1360cd737b466eb9 162 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 10-03-2017 IPR030489 Transcription regulator Rrf2-type, conserved site RG49_RS22415 de6f99239b4941ac1360cd737b466eb9 162 Hamap MF_01176 HTH-type transcriptional regulator IscR [iscR]. 1 162 45.923 T 10-03-2017 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 Pfam PF12796 Ankyrin repeats (3 copies) 78 174 1.0E-9 T 10-03-2017 IPR020683 Ankyrin repeat-containing domain RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 SUPERFAMILY SSF48403 12 201 1.37E-45 T 10-03-2017 IPR020683 Ankyrin repeat-containing domain RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 SMART SM00248 138 172 9.4 T 10-03-2017 IPR002110 Ankyrin repeat GO:0005515 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 SMART SM00248 176 201 600.0 T 10-03-2017 IPR002110 Ankyrin repeat GO:0005515 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 SMART SM00248 71 100 150.0 T 10-03-2017 IPR002110 Ankyrin repeat GO:0005515 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 SMART SM00248 5 34 2200.0 T 10-03-2017 IPR002110 Ankyrin repeat GO:0005515 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 SMART SM00248 107 134 980.0 T 10-03-2017 IPR002110 Ankyrin repeat GO:0005515 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 SMART SM00248 38 67 0.0017 T 10-03-2017 IPR002110 Ankyrin repeat GO:0005515 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 Pfam PF13637 Ankyrin repeats (many copies) 13 59 1.6E-7 T 10-03-2017 RG49_RS09550 69b4759cf5429d6ae98c42bf3b4dafa3 201 Gene3D G3DSA:1.25.40.20 12 201 5.0E-45 T 10-03-2017 IPR020683 Ankyrin repeat-containing domain RG49_RS23445 bc76af2c847ecf8f8e2068c3c0635024 182 Pfam PF04315 Elongation factor P hydroxylase 13 175 8.7E-81 T 10-03-2017 IPR007411 Elongation factor P hydroxylase RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 Gene3D G3DSA:3.40.50.1100 97 176 6.8E-21 T 10-03-2017 RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 SUPERFAMILY SSF53686 5 390 4.06E-142 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 PIRSF PIRSF001413 1 397 8.3E-173 T 10-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 2 391 49.287 T 10-03-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 Gene3D G3DSA:3.40.50.1100 177 392 4.0E-93 T 10-03-2017 RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 80 94 - T 10-03-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 375 1.1E-50 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS04280 6928ee6ba77b77478258aa92b0d2de90 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 8 389 8.1E-189 T 10-03-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 375 611 1.3E-120 T 10-03-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 SUPERFAMILY SSF88946 113 446 6.41E-104 T 10-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Pfam PF04542 Sigma-70 region 2 379 448 1.7E-21 T 10-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 572 598 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 403 416 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Gene3D G3DSA:1.10.601.10 110 448 2.2E-140 T 10-03-2017 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 375 600 3.5E-38 T 10-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 612 46.833 T 10-03-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Pfam PF04546 Sigma-70, non-essential region 137 348 3.2E-75 T 10-03-2017 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 SUPERFAMILY SSF88659 509 611 2.55E-25 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Pfam PF00140 Sigma-70 factor, region 1.2 96 126 1.4E-12 T 10-03-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Gene3D G3DSA:1.10.10.10 543 612 1.3E-32 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Pfam PF03979 Sigma-70 factor, region 1.1 4 79 2.8E-30 T 10-03-2017 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Pfam PF04539 Sigma-70 region 3 458 533 3.4E-29 T 10-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 PRINTS PR00046 Major sigma-70 factor signature 427 435 6.3E-31 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 PRINTS PR00046 Major sigma-70 factor signature 572 587 6.3E-31 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 PRINTS PR00046 Major sigma-70 factor signature 551 563 6.3E-31 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 PRINTS PR00046 Major sigma-70 factor signature 587 598 6.3E-31 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 PRINTS PR00046 Major sigma-70 factor signature 403 416 6.3E-31 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Gene3D G3DSA:1.10.10.10 452 503 1.8E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 SUPERFAMILY SSF88659 452 525 8.78E-21 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS19390 96380dec55e6d24902573840d3903eb5 613 Pfam PF04545 Sigma-70, region 4 547 600 8.9E-19 T 10-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 Gene3D G3DSA:3.40.190.10 197 252 1.2E-8 T 10-03-2017 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 Pfam PF03466 LysR substrate binding domain 89 293 3.7E-37 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 Gene3D G3DSA:3.40.190.10 82 196 2.0E-23 T 10-03-2017 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 SUPERFAMILY SSF46785 2 111 7.12E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.6E-21 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 SUPERFAMILY SSF53850 89 295 1.45E-31 T 10-03-2017 RG49_RS15350 ac8e3afa304a1b4468716bc6c4fd4a42 297 Gene3D G3DSA:1.10.10.10 2 81 3.9E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16485 03ddb941ec5f7556890ce78365da94d2 99 Pfam PF01527 Transposase 12 78 5.6E-9 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS16485 03ddb941ec5f7556890ce78365da94d2 99 SUPERFAMILY SSF46689 11 96 6.45E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16485 03ddb941ec5f7556890ce78365da94d2 99 Gene3D G3DSA:1.10.10.60 16 93 5.2E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02750 03ddb941ec5f7556890ce78365da94d2 99 Pfam PF01527 Transposase 12 78 5.6E-9 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS02750 03ddb941ec5f7556890ce78365da94d2 99 SUPERFAMILY SSF46689 11 96 6.45E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02750 03ddb941ec5f7556890ce78365da94d2 99 Gene3D G3DSA:1.10.10.60 16 93 5.2E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03085 03ddb941ec5f7556890ce78365da94d2 99 Pfam PF01527 Transposase 12 78 5.6E-9 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS03085 03ddb941ec5f7556890ce78365da94d2 99 SUPERFAMILY SSF46689 11 96 6.45E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS03085 03ddb941ec5f7556890ce78365da94d2 99 Gene3D G3DSA:1.10.10.60 16 93 5.2E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS05545 03ddb941ec5f7556890ce78365da94d2 99 Pfam PF01527 Transposase 12 78 5.6E-9 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS05545 03ddb941ec5f7556890ce78365da94d2 99 SUPERFAMILY SSF46689 11 96 6.45E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS05545 03ddb941ec5f7556890ce78365da94d2 99 Gene3D G3DSA:1.10.10.60 16 93 5.2E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS07725 884a1f2ffa4258b2a97a4732ced1b997 266 Gene3D G3DSA:3.40.50.1360 1 264 1.4E-112 T 10-03-2017 RG49_RS07725 884a1f2ffa4258b2a97a4732ced1b997 266 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 259 1.5E-144 T 10-03-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 RG49_RS07725 884a1f2ffa4258b2a97a4732ced1b997 266 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 9 224 5.9E-22 T 10-03-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 RG49_RS07725 884a1f2ffa4258b2a97a4732ced1b997 266 SUPERFAMILY SSF100950 1 263 6.7E-105 T 10-03-2017 RG49_RS07725 884a1f2ffa4258b2a97a4732ced1b997 266 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 247 40.893 T 10-03-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 RG49_RS07725 884a1f2ffa4258b2a97a4732ced1b997 266 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 125 143 - T 10-03-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 RG49_RS02035 238a138012d05b6096abecddb1b9b465 460 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 3 459 5.7E-185 T 10-03-2017 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 RG49_RS02035 238a138012d05b6096abecddb1b9b465 460 Pfam PF13520 Amino acid permease 5 442 7.1E-79 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS02035 238a138012d05b6096abecddb1b9b465 460 PIRSF PIRSF006060 1 459 4.3E-44 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 SUPERFAMILY SSF52540 302 526 8.46E-48 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 SUPERFAMILY SSF52540 11 243 2.27E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 Gene3D G3DSA:3.40.50.300 322 535 6.1E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 Pfam PF12848 ABC transporter 230 306 2.4E-11 T 10-03-2017 IPR032781 ABC-transporter extension domain RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 Pfam PF00005 ABC transporter 22 191 1.3E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 Pfam PF00005 ABC transporter 340 473 1.5E-24 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 Gene3D G3DSA:3.40.50.300 11 109 7.6E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 Gene3D G3DSA:3.40.50.300 141 286 7.6E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 SMART SM00382 348 522 9.2E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 SMART SM00382 31 236 3.5E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS11955 4c6ededf23149235593dabf90ba12dda 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 1.6E-295 T 10-03-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD RG49_RS05925 66e7df825c29df2dd996d2dd7ae4d09a 169 SUPERFAMILY SSF52540 31 147 3.4E-27 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05925 66e7df825c29df2dd996d2dd7ae4d09a 169 Hamap MF_01179 Cell division inhibitor SulA [sulA]. 1 169 42.316 T 10-03-2017 IPR004596 Cell division suppressor protein, SulA GO:0009276|GO:0009432|GO:0051782 RG49_RS05925 66e7df825c29df2dd996d2dd7ae4d09a 169 PIRSF PIRSF003093 1 169 6.4E-89 T 10-03-2017 IPR004596 Cell division suppressor protein, SulA GO:0009276|GO:0009432|GO:0051782 RG49_RS05925 66e7df825c29df2dd996d2dd7ae4d09a 169 TIGRFAM TIGR00623 sula: cell division inhibitor SulA 2 169 1.3E-101 T 10-03-2017 IPR004596 Cell division suppressor protein, SulA GO:0009276|GO:0009432|GO:0051782 RG49_RS05925 66e7df825c29df2dd996d2dd7ae4d09a 169 Pfam PF03846 Cell division inhibitor SulA 6 119 2.2E-55 T 10-03-2017 IPR004596 Cell division suppressor protein, SulA GO:0009276|GO:0009432|GO:0051782 RG49_RS05925 66e7df825c29df2dd996d2dd7ae4d09a 169 Gene3D G3DSA:3.40.50.300 31 147 1.3E-39 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09815 b23db478793254ff15d48e1a7f3288ad 153 Pfam PF03245 Bacteriophage Rz lysis protein 30 153 3.5E-50 T 10-03-2017 IPR004929 Bacteriophage Rz lysis protein GO:0019076|GO:0019835 RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 PIRSF PIRSF015753 5 324 5.7E-134 T 10-03-2017 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 Gene3D G3DSA:1.20.1050.10 179 288 1.7E-27 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 Gene3D G3DSA:3.40.30.10 43 178 6.2E-19 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 SUPERFAMILY SSF52833 41 99 1.57E-14 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 SUPERFAMILY SSF52833 126 162 1.57E-14 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 Pfam PF13410 Glutathione S-transferase, C-terminal domain 204 257 1.4E-12 T 10-03-2017 RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 158 7.3E-23 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS19195 33859abd93ad005a839c1c145e0e2e4a 328 SUPERFAMILY SSF47616 176 324 4.18E-36 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS05115 2c7fba0bca3eb2927287f2bfeffef676 274 Gene3D G3DSA:3.90.1200.10 75 264 5.0E-13 T 10-03-2017 RG49_RS05115 2c7fba0bca3eb2927287f2bfeffef676 274 Hamap MF_01604 Thiamine kinase [thiK]. 1 274 70.539 T 10-03-2017 IPR014093 Thiamine kinase GO:0006772|GO:0016310|GO:0019165 KEGG: 00730+2.7.1.89|MetaCyc: PWY-6896 RG49_RS05115 2c7fba0bca3eb2927287f2bfeffef676 274 Pfam PF01636 Phosphotransferase enzyme family 25 222 3.1E-14 T 10-03-2017 IPR002575 Aminoglycoside phosphotransferase RG49_RS05115 2c7fba0bca3eb2927287f2bfeffef676 274 TIGRFAM TIGR02721 ycfN_thiK: thiamine kinase 26 270 7.0E-102 T 10-03-2017 IPR014093 Thiamine kinase GO:0006772|GO:0016310|GO:0019165 KEGG: 00730+2.7.1.89|MetaCyc: PWY-6896 RG49_RS05115 2c7fba0bca3eb2927287f2bfeffef676 274 SUPERFAMILY SSF56112 18 268 1.9E-29 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 73 93 1.1E-41 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 13 30 1.1E-41 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 97 119 1.1E-41 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 123 141 1.1E-41 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 Pfam PF02556 Preprotein translocase subunit SecB 5 144 7.1E-58 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 5 147 2.5E-71 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 Gene3D G3DSA:3.10.420.10 2 151 4.3E-65 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 Hamap MF_00821 Protein-export protein SecB [secB]. 1 145 33.544 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS16360 cdf158db6f741adec4ab6e18b09bab2a 155 SUPERFAMILY SSF54611 2 141 1.35E-53 T 10-03-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 RG49_RS03390 7efd776e44207fff5a9846647f7969de 286 Pfam PF00248 Aldo/keto reductase family 15 283 5.9E-48 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS03390 7efd776e44207fff5a9846647f7969de 286 SUPERFAMILY SSF51430 11 284 2.36E-63 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS03390 7efd776e44207fff5a9846647f7969de 286 Gene3D G3DSA:3.20.20.100 12 285 1.4E-60 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS06210 81fa0f48ee292b07953b4dc629a58709 586 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 11 404 2.7E-173 T 10-03-2017 IPR003776 YcaO-like domain RG49_RS06210 81fa0f48ee292b07953b4dc629a58709 586 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 59 391 1.7E-81 T 10-03-2017 IPR003776 YcaO-like domain RG49_RS21935 d693b6eca751c54da0bd7de3aa2455b6 158 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 23 148 1.7E-31 T 10-03-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain RG49_RS21935 d693b6eca751c54da0bd7de3aa2455b6 158 SUPERFAMILY SSF55961 14 157 2.54E-34 T 10-03-2017 RG49_RS21935 d693b6eca751c54da0bd7de3aa2455b6 158 Gene3D G3DSA:3.30.530.20 14 155 7.0E-49 T 10-03-2017 IPR023393 START-like domain RG49_RS22975 d3f02c5493f8927d19b932ad13d2c154 434 Hamap MF_01034 UPF0214 protein YfeW [yfeW]. 1 432 83.242 T 10-03-2017 IPR022849 Peptidase S12, UPF0214, YfeW-type RG49_RS22975 d3f02c5493f8927d19b932ad13d2c154 434 SUPERFAMILY SSF56601 39 400 2.07E-76 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS22975 d3f02c5493f8927d19b932ad13d2c154 434 Gene3D G3DSA:3.40.710.10 28 399 1.1E-87 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS22975 d3f02c5493f8927d19b932ad13d2c154 434 Pfam PF00144 Beta-lactamase 44 412 4.4E-70 T 10-03-2017 IPR001466 Beta-lactamase-related RG49_RS19150 6aec5bac96c9e37e3a4842541e9fb904 454 Pfam PF03315 Serine dehydratase beta chain 3 155 3.8E-54 T 10-03-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 RG49_RS19150 6aec5bac96c9e37e3a4842541e9fb904 454 SUPERFAMILY SSF143548 16 158 1.46E-43 T 10-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 RG49_RS19150 6aec5bac96c9e37e3a4842541e9fb904 454 Gene3D G3DSA:3.30.1330.90 10 157 2.9E-52 T 10-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 RG49_RS19150 6aec5bac96c9e37e3a4842541e9fb904 454 Pfam PF03313 Serine dehydratase alpha chain 184 448 2.7E-99 T 10-03-2017 IPR005130 Serine dehydratase-like, alpha subunit RG49_RS19150 6aec5bac96c9e37e3a4842541e9fb904 454 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 7.2E-218 T 10-03-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 RG49_RS18880 7b94eebf779c750e05e2ca5fdba4a318 100 Hamap MF_01029 UPF0213 protein YhbQ [yhbQ]. 1 92 32.601 T 10-03-2017 IPR022992 Uncharacterised protein family UPF0213, GIY-YIG endonuclease RG49_RS18880 7b94eebf779c750e05e2ca5fdba4a318 100 Pfam PF01541 GIY-YIG catalytic domain 4 75 3.8E-14 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS18880 7b94eebf779c750e05e2ca5fdba4a318 100 SUPERFAMILY SSF82771 3 72 9.55E-12 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS18880 7b94eebf779c750e05e2ca5fdba4a318 100 SMART SM00465 2 81 4.5E-4 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS04110 17517a241b56a96f753c1748f4deac12 262 Gene3D G3DSA:3.40.50.720 2 253 5.2E-62 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04110 17517a241b56a96f753c1748f4deac12 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.0E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04110 17517a241b56a96f753c1748f4deac12 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.0E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04110 17517a241b56a96f753c1748f4deac12 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.0E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04110 17517a241b56a96f753c1748f4deac12 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 4.8E-85 T 10-03-2017 RG49_RS04110 17517a241b56a96f753c1748f4deac12 262 SUPERFAMILY SSF51735 6 253 2.06E-62 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04110 17517a241b56a96f753c1748f4deac12 262 PIRSF PIRSF000094 1 260 3.0E-125 T 10-03-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 SUPERFAMILY SSF48179 386 467 5.53E-18 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 Gene3D G3DSA:1.10.1040.10 190 285 1.6E-28 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 Gene3D G3DSA:1.10.1040.10 387 467 1.1E-20 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 285 2.9E-28 T 10-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 387 466 4.5E-15 T 10-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 185 210 - T 10-03-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 SUPERFAMILY SSF48179 187 294 1.7E-27 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 Gene3D G3DSA:3.40.50.720 4 189 2.8E-62 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 SUPERFAMILY SSF51735 2 187 5.71E-57 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 184 2.9E-65 T 10-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS03420 8bcbf7af8761b1be1b79b0146227392c 475 TIGRFAM TIGR02279 PaaC-3OHAcCoADH: 3-hydroxyacyl-CoA dehydrogenase PaaC 1 474 2.8E-258 T 10-03-2017 IPR011967 3-hydroxyacyl-CoA dehydrogenase PaaC GO:0008691|GO:0010124 RG49_RS05730 bfd95b6f6e687e24292a2ae6d78e9566 342 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 44 337 1.0E-94 T 10-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain RG49_RS05730 bfd95b6f6e687e24292a2ae6d78e9566 342 Gene3D G3DSA:3.40.50.2300 45 161 7.3E-14 T 10-03-2017 RG49_RS05730 bfd95b6f6e687e24292a2ae6d78e9566 342 Gene3D G3DSA:3.40.50.2300 162 306 4.5E-28 T 10-03-2017 RG49_RS05730 bfd95b6f6e687e24292a2ae6d78e9566 342 SUPERFAMILY SSF53822 45 300 1.99E-38 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS05730 bfd95b6f6e687e24292a2ae6d78e9566 342 TIGRFAM TIGR02955 TMAO_TorT: TMAO reductase system periplasmic protein TorT 46 334 5.3E-132 T 10-03-2017 IPR014301 TMAO reductase system periplasmic, TorT RG49_RS16915 21e767f9db07c80048f10d7a0187a4b3 440 Pfam PF00083 Sugar (and other) transporter 23 232 1.6E-24 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS16915 21e767f9db07c80048f10d7a0187a4b3 440 Gene3D G3DSA:1.20.1250.20 13 232 9.1E-24 T 10-03-2017 RG49_RS16915 21e767f9db07c80048f10d7a0187a4b3 440 Gene3D G3DSA:1.20.1250.20 250 438 2.6E-16 T 10-03-2017 RG49_RS16915 21e767f9db07c80048f10d7a0187a4b3 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 308 325 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS16915 21e767f9db07c80048f10d7a0187a4b3 440 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 30 425 1.4E-153 T 10-03-2017 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 RG49_RS16915 21e767f9db07c80048f10d7a0187a4b3 440 Pfam PF07690 Major Facilitator Superfamily 283 435 2.3E-12 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS16915 21e767f9db07c80048f10d7a0187a4b3 440 SUPERFAMILY SSF103473 19 439 1.96E-64 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS17690 1e1040e2513d8989aefd30721b82ae41 408 Pfam PF01676 Metalloenzyme superfamily 3 388 3.1E-49 T 10-03-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 RG49_RS17690 1e1040e2513d8989aefd30721b82ae41 408 SUPERFAMILY SSF53649 3 100 2.62E-56 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS17690 1e1040e2513d8989aefd30721b82ae41 408 SUPERFAMILY SSF53649 230 401 2.62E-56 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS17690 1e1040e2513d8989aefd30721b82ae41 408 PIRSF PIRSF001491 1 402 4.8E-116 T 10-03-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 RG49_RS17690 1e1040e2513d8989aefd30721b82ae41 408 Gene3D G3DSA:3.40.720.10 233 401 4.4E-61 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS17690 1e1040e2513d8989aefd30721b82ae41 408 Gene3D G3DSA:3.40.720.10 2 100 4.4E-61 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 SUPERFAMILY SSF55681 4 204 1.41E-68 T 10-03-2017 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 Gene3D G3DSA:3.90.1550.10 4 202 8.9E-71 T 10-03-2017 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 Pfam PF03099 Biotin/lipoate A/B protein ligase family 62 159 6.2E-7 T 10-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 128 5.0E-24 T 10-03-2017 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 26 204 2.8E-84 T 10-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 Hamap MF_00013 Octanoyltransferase [lipB]. 5 206 37.651 T 10-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 PIRSF PIRSF016262 2 210 4.5E-57 T 10-03-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 RG49_RS07955 ee87fe2b237539e2d51ffc7a7dce4e35 213 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 10-03-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 9.7E-8 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 Pfam PF13633 Prokaryotic N-terminal methylation site 6 27 1.3E-8 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 Gene3D G3DSA:2.10.70.20 151 198 4.4E-22 T 10-03-2017 RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 6 195 7.0E-53 T 10-03-2017 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 Pfam PF11612 Type II secretion system (T2SS), protein J 58 193 1.8E-34 T 10-03-2017 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 SUPERFAMILY SSF54523 46 197 4.87E-44 T 10-03-2017 RG49_RS20020 de8771bded4e293ec8496f9d4f06d74a 199 Gene3D G3DSA:3.10.610.10 38 148 1.6E-43 T 10-03-2017 RG49_RS22395 4539360304fc8443a12558e1c4d8c0f3 426 SUPERFAMILY SSF63520 231 333 1.96E-15 T 10-03-2017 IPR011608 PRD domain GO:0006355 RG49_RS22395 4539360304fc8443a12558e1c4d8c0f3 426 Gene3D G3DSA:1.10.1790.10 231 332 1.1E-15 T 10-03-2017 IPR011608 PRD domain GO:0006355 RG49_RS22395 4539360304fc8443a12558e1c4d8c0f3 426 Pfam PF00874 PRD domain 131 216 1.3E-9 T 10-03-2017 IPR011608 PRD domain GO:0006355 RG49_RS22395 4539360304fc8443a12558e1c4d8c0f3 426 Pfam PF00874 PRD domain 240 328 4.6E-11 T 10-03-2017 IPR011608 PRD domain GO:0006355 RG49_RS07100 579da4df312700556fdc4b955f97e77e 234 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 230 5.5E-60 T 10-03-2017 RG49_RS12475 8b9d2bdcb154b4d3d73eaff78894be43 326 SUPERFAMILY SSF52266 10 265 3.3E-42 T 10-03-2017 IPR013830 SGNH hydrolase-type esterase domain RG49_RS12475 8b9d2bdcb154b4d3d73eaff78894be43 326 SUPERFAMILY SSF52266 297 323 3.3E-42 T 10-03-2017 IPR013830 SGNH hydrolase-type esterase domain RG49_RS13140 fe3f3fe9e9fd4a541905a78c2ba045f0 325 SUPERFAMILY SSF55681 12 320 9.38E-85 T 10-03-2017 RG49_RS13140 fe3f3fe9e9fd4a541905a78c2ba045f0 325 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 17 320 1.0E-132 T 10-03-2017 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 RG49_RS13140 fe3f3fe9e9fd4a541905a78c2ba045f0 325 Gene3D G3DSA:3.30.930.10 15 320 1.3E-74 T 10-03-2017 RG49_RS13140 fe3f3fe9e9fd4a541905a78c2ba045f0 325 PRINTS PR00982 Lysyl-tRNA synthetase signature 31 41 3.4E-6 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13140 fe3f3fe9e9fd4a541905a78c2ba045f0 325 PRINTS PR00982 Lysyl-tRNA synthetase signature 99 116 3.4E-6 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS13140 fe3f3fe9e9fd4a541905a78c2ba045f0 325 Hamap MF_00174 Elongation factor P--(R)-beta-lysine ligase [epmA]. 2 325 57.938 T 10-03-2017 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 RG49_RS13140 fe3f3fe9e9fd4a541905a78c2ba045f0 325 Pfam PF00152 tRNA synthetases class II (D, K and N) 15 321 7.4E-47 T 10-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS10405 da5bbb3f3302ba7f57f2068b506736fa 208 SUPERFAMILY SSF51306 113 206 1.06E-29 T 10-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C RG49_RS10405 da5bbb3f3302ba7f57f2068b506736fa 208 Pfam PF00717 Peptidase S24-like 120 194 1.6E-19 T 10-03-2017 IPR019759 Peptidase S24/S26A/S26B RG49_RS10405 da5bbb3f3302ba7f57f2068b506736fa 208 Gene3D G3DSA:1.10.260.40 1 65 7.4E-20 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS10405 da5bbb3f3302ba7f57f2068b506736fa 208 SMART SM00530 7 62 1.6E-8 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS10405 da5bbb3f3302ba7f57f2068b506736fa 208 Gene3D G3DSA:2.10.109.10 114 206 1.2E-33 T 10-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain RG49_RS10405 da5bbb3f3302ba7f57f2068b506736fa 208 SUPERFAMILY SSF47413 1 69 1.2E-14 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS10405 da5bbb3f3302ba7f57f2068b506736fa 208 Pfam PF01381 Helix-turn-helix 8 62 1.6E-10 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS06850 c46426c216e7cf06b47dab106a168a78 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 4.7E-43 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06850 c46426c216e7cf06b47dab106a168a78 306 SUPERFAMILY SSF161098 91 288 3.79E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06850 c46426c216e7cf06b47dab106a168a78 306 Gene3D G3DSA:1.10.3720.10 88 301 3.5E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS08540 1d46f1a2f2ddb83eab40ce091ccca85a 271 Pfam PF09339 IclR helix-turn-helix domain 23 73 6.5E-12 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS08540 1d46f1a2f2ddb83eab40ce091ccca85a 271 SMART SM00346 21 111 3.0E-35 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS08540 1d46f1a2f2ddb83eab40ce091ccca85a 271 SUPERFAMILY SSF46785 22 94 9.89E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08540 1d46f1a2f2ddb83eab40ce091ccca85a 271 Gene3D G3DSA:3.30.450.40 93 267 4.9E-53 T 10-03-2017 IPR029016 GAF domain-like RG49_RS08540 1d46f1a2f2ddb83eab40ce091ccca85a 271 SUPERFAMILY SSF55781 86 266 1.9E-48 T 10-03-2017 IPR029016 GAF domain-like RG49_RS08540 1d46f1a2f2ddb83eab40ce091ccca85a 271 Pfam PF01614 Bacterial transcriptional regulator 141 263 2.4E-41 T 10-03-2017 IPR014757 Transcription regulator IclR, C-terminal RG49_RS08540 1d46f1a2f2ddb83eab40ce091ccca85a 271 Gene3D G3DSA:1.10.10.10 19 92 5.7E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23170 5c0c01bcd35e5eb9e2aac270529233d1 729 Pfam PF05231 MASE1 16 314 8.3E-60 T 10-03-2017 IPR007895 MASE1 RG49_RS23170 5c0c01bcd35e5eb9e2aac270529233d1 729 SMART SM00267 315 473 1.2E-27 T 10-03-2017 IPR000160 GGDEF domain RG49_RS23170 5c0c01bcd35e5eb9e2aac270529233d1 729 SMART SM00052 487 729 1.4E-96 T 10-03-2017 IPR001633 EAL domain RG49_RS23170 5c0c01bcd35e5eb9e2aac270529233d1 729 Pfam PF00563 EAL domain 493 724 3.5E-59 T 10-03-2017 IPR001633 EAL domain RG49_RS23170 5c0c01bcd35e5eb9e2aac270529233d1 729 SUPERFAMILY SSF141868 493 728 3.27E-66 T 10-03-2017 IPR001633 EAL domain RG49_RS23170 5c0c01bcd35e5eb9e2aac270529233d1 729 SUPERFAMILY SSF55073 331 436 2.67E-5 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS23170 5c0c01bcd35e5eb9e2aac270529233d1 729 Gene3D G3DSA:3.20.20.450 493 728 2.4E-64 T 10-03-2017 IPR001633 EAL domain RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 241 261 2.7E-7 T 10-03-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 173 189 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 93 108 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 56 73 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 215 231 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 241 259 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 16 32 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 197 212 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 PRINTS PR01714 Ferric iron reductase signature 125 139 1.2E-76 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 Pfam PF06276 Ferric iron reductase FhuF-like transporter 93 236 1.8E-30 T 10-03-2017 IPR022770 Ferric iron reductase FhuF domain RG49_RS12105 221ee60226edbd6e4fa70650e186a3e3 262 TIGRFAM TIGR03951 Fe_III_red_FhuF: siderophore-iron reductase FhuF 87 262 4.5E-69 T 10-03-2017 IPR008090 Ferric iron reductase RG49_RS02475 231528f477bca1979085cef5640e9465 1116 SUPERFAMILY SSF88874 897 1001 3.53E-32 T 10-03-2017 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 SUPERFAMILY SSF88874 1064 1115 3.53E-32 T 10-03-2017 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF03335 Phage tail fibre repeat 1017 1026 2.9 T 10-03-2017 IPR005003 Bacteriophage lambda, Stf, side tail fibre-repeat-1 GO:0005198 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF03335 Phage tail fibre repeat 1002 1015 0.044 T 10-03-2017 IPR005003 Bacteriophage lambda, Stf, side tail fibre-repeat-1 GO:0005198 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF03335 Phage tail fibre repeat 1051 1064 0.11 T 10-03-2017 IPR005003 Bacteriophage lambda, Stf, side tail fibre-repeat-1 GO:0005198 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF03335 Phage tail fibre repeat 1066 1077 0.99 T 10-03-2017 IPR005003 Bacteriophage lambda, Stf, side tail fibre-repeat-1 GO:0005198 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF03335 Phage tail fibre repeat 970 983 0.31 T 10-03-2017 IPR005003 Bacteriophage lambda, Stf, side tail fibre-repeat-1 GO:0005198 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF03335 Phage tail fibre repeat 1075 1086 0.9 T 10-03-2017 IPR005003 Bacteriophage lambda, Stf, side tail fibre-repeat-1 GO:0005198 RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Gene3D G3DSA:3.90.1340.10 898 956 3.4E-9 T 10-03-2017 IPR011083 Phage tail collar domain RG49_RS02475 231528f477bca1979085cef5640e9465 1116 SUPERFAMILY SSF49464 4 80 1.22E-6 T 10-03-2017 IPR008969 Carboxypeptidase-like, regulatory domain RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Gene3D G3DSA:2.60.40.1120 5 81 8.4E-7 T 10-03-2017 IPR014766 Carboxypeptidase, regulatory domain RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF07484 Phage Tail Collar Domain 907 953 9.4E-11 T 10-03-2017 IPR011083 Phage tail collar domain RG49_RS02475 231528f477bca1979085cef5640e9465 1116 Pfam PF08400 Prophage tail fibre N-terminal 1 134 1.1E-72 T 10-03-2017 IPR013609 Bacteriophage 933W, L0121, tail fibre, N-terminal RG49_RS20765 48f6c995576b4b9606bc8f6faa743c95 269 Gene3D G3DSA:1.10.10.10 22 105 9.3E-8 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20765 48f6c995576b4b9606bc8f6faa743c95 269 SMART SM00862 25 103 9.2E-7 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS20765 48f6c995576b4b9606bc8f6faa743c95 269 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 102 4.1E-9 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS20765 48f6c995576b4b9606bc8f6faa743c95 269 SUPERFAMILY SSF46894 20 103 1.93E-7 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS10015 a8a68087e99034e4178fd12d3f45941e 152 SUPERFAMILY SSF49764 22 151 4.36E-40 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS10015 a8a68087e99034e4178fd12d3f45941e 152 Pfam PF00011 Hsp20/alpha crystallin family 50 150 9.4E-27 T 10-03-2017 IPR002068 Alpha crystallin/Hsp20 domain RG49_RS10015 a8a68087e99034e4178fd12d3f45941e 152 Gene3D G3DSA:2.60.40.790 3 151 5.5E-46 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS19650 2eb89a6976c828a20fdfc132c035bc6d 535 Gene3D G3DSA:3.10.105.10 292 503 4.5E-61 T 10-03-2017 RG49_RS19650 2eb89a6976c828a20fdfc132c035bc6d 535 SUPERFAMILY SSF53850 26 528 8.54E-134 T 10-03-2017 RG49_RS19650 2eb89a6976c828a20fdfc132c035bc6d 535 Gene3D G3DSA:3.90.76.10 42 217 5.4E-50 T 10-03-2017 RG49_RS19650 2eb89a6976c828a20fdfc132c035bc6d 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 453 2.4E-79 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS19650 2eb89a6976c828a20fdfc132c035bc6d 535 PIRSF PIRSF002741 3 535 2.3E-103 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS06845 235a1842601e3ba0e8f9ca8893f2ddbe 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 78 3.6E-15 T 10-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain RG49_RS06845 235a1842601e3ba0e8f9ca8893f2ddbe 303 SUPERFAMILY SSF161098 96 283 1.1E-28 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06845 235a1842601e3ba0e8f9ca8893f2ddbe 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 302 1.0E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06845 235a1842601e3ba0e8f9ca8893f2ddbe 303 Gene3D G3DSA:1.10.3720.10 93 299 1.4E-28 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 Pfam PF00136 DNA polymerase family B 382 735 4.6E-42 T 10-03-2017 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 Gene3D G3DSA:3.30.420.10 148 365 9.1E-37 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 SUPERFAMILY SSF53098 3 389 2.08E-98 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 SMART SM00486 148 555 2.0E-84 T 10-03-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 415 428 7.0E-10 T 10-03-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 489 501 7.0E-10 T 10-03-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 541 549 7.0E-10 T 10-03-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 ProSitePatterns PS00116 DNA polymerase family B signature. 543 551 - T 10-03-2017 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 Pfam PF03104 DNA polymerase family B, exonuclease domain 200 296 9.7E-7 T 10-03-2017 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 Pfam PF03104 DNA polymerase family B, exonuclease domain 74 164 5.1E-5 T 10-03-2017 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 SUPERFAMILY SSF56672 394 783 4.89E-116 T 10-03-2017 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 Gene3D G3DSA:3.90.1600.10 512 644 7.0E-11 T 10-03-2017 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS11575 26713bba2c95a75bda4494a72658d670 783 Gene3D G3DSA:3.90.1600.10 400 431 7.0E-11 T 10-03-2017 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS04435 7eacaaa70e2e9edb3d9724d5b112c85b 301 SUPERFAMILY SSF52151 1 294 5.23E-57 T 10-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 RG49_RS04435 7eacaaa70e2e9edb3d9724d5b112c85b 301 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 11 43 - T 10-03-2017 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 RG49_RS04435 7eacaaa70e2e9edb3d9724d5b112c85b 301 Pfam PF01734 Patatin-like phospholipase 8 165 7.2E-24 T 10-03-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 RG49_RS04435 7eacaaa70e2e9edb3d9724d5b112c85b 301 Gene3D G3DSA:3.40.1090.10 8 170 2.4E-6 T 10-03-2017 RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 Gene3D G3DSA:3.40.190.10 94 182 1.6E-18 T 10-03-2017 RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 Gene3D G3DSA:1.10.10.10 8 92 2.1E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 SUPERFAMILY SSF53850 94 292 2.71E-30 T 10-03-2017 RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 SUPERFAMILY SSF46785 8 92 1.6E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 Pfam PF03466 LysR substrate binding domain 93 291 1.6E-37 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 Gene3D G3DSA:3.40.190.10 183 269 6.8E-23 T 10-03-2017 RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.7E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.7E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.7E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23115 a349e53e7e641c59727a480c8e6f1826 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 7.9E-22 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19425 b9f58c8e73f48c10bddd1dac4690d710 201 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 176 2.1E-77 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS19425 b9f58c8e73f48c10bddd1dac4690d710 201 Pfam PF05683 Fumarase C-terminus 9 175 7.5E-40 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS19425 b9f58c8e73f48c10bddd1dac4690d710 201 Gene3D G3DSA:3.20.130.10 1 174 7.1E-68 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS19425 b9f58c8e73f48c10bddd1dac4690d710 201 SUPERFAMILY SSF117457 3 174 1.57E-57 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS08530 e179b809de4ea073c9f8df3ad66f6655 258 SUPERFAMILY SSF51658 1 257 2.76E-83 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS08530 e179b809de4ea073c9f8df3ad66f6655 258 PIRSF PIRSF006241 1 258 8.3E-97 T 10-03-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 RG49_RS08530 e179b809de4ea073c9f8df3ad66f6655 258 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 4.3E-32 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS08530 e179b809de4ea073c9f8df3ad66f6655 258 Gene3D G3DSA:3.20.20.150 1 257 1.3E-88 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS08530 e179b809de4ea073c9f8df3ad66f6655 258 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 3 255 1.1E-125 T 10-03-2017 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 RG49_RS05555 f4e12452e056cbc902a874122fd99f11 452 SUPERFAMILY SSF55073 287 442 7.85E-45 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS05555 f4e12452e056cbc902a874122fd99f11 452 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 280 443 1.8E-45 T 10-03-2017 IPR000160 GGDEF domain RG49_RS05555 f4e12452e056cbc902a874122fd99f11 452 Pfam PF17158 Membrane-associated sensor, integral membrane domain 40 274 1.5E-69 T 10-03-2017 IPR033424 Membrane-associated sensor domain RG49_RS05555 f4e12452e056cbc902a874122fd99f11 452 SMART SM00267 271 443 4.2E-69 T 10-03-2017 IPR000160 GGDEF domain RG49_RS05555 f4e12452e056cbc902a874122fd99f11 452 Pfam PF00990 Diguanylate cyclase, GGDEF domain 282 439 1.8E-48 T 10-03-2017 IPR000160 GGDEF domain RG49_RS05555 f4e12452e056cbc902a874122fd99f11 452 Gene3D G3DSA:3.30.70.270 284 443 1.3E-48 T 10-03-2017 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Gene3D G3DSA:1.10.3810.10 205 381 3.7E-62 T 10-03-2017 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 68 795 0.0 T 10-03-2017 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Gene3D G3DSA:1.20.5.100 54 96 2.6E-25 T 10-03-2017 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 PIRSF PIRSF002799 13 843 0.0 T 10-03-2017 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Gene3D G3DSA:3.30.2060.10 111 200 1.2E-34 T 10-03-2017 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 SUPERFAMILY SSF56601 412 778 8.45E-104 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 SUPERFAMILY SSF56601 362 384 8.45E-104 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 SUPERFAMILY SSF53955 196 403 7.59E-65 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Pfam PF00905 Penicillin binding protein transpeptidase domain 473 715 8.2E-24 T 10-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Pfam PF00912 Transglycosylase 209 380 2.4E-54 T 10-03-2017 IPR001264 Glycosyl transferase, family 51 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Pfam PF14814 Bifunctional transglycosylase second domain 113 197 7.9E-28 T 10-03-2017 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Pfam PF14812 Transmembrane domain of transglycosylase PBP1 at N-terminal 1 79 1.8E-26 T 10-03-2017 IPR032730 Transglycosylase PBP1b, N-terminal transmembrane domain RG49_RS11080 b6ac06102a593d5d05c3b03edb5fe382 844 Gene3D G3DSA:3.40.710.10 382 798 1.2E-109 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS14865 3480cd573d47a9957acf9fa3fe3f7b3c 210 Pfam PF01926 50S ribosome-binding GTPase 28 146 8.5E-20 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS14865 3480cd573d47a9957acf9fa3fe3f7b3c 210 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 14 197 28.826 T 10-03-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 RG49_RS14865 3480cd573d47a9957acf9fa3fe3f7b3c 210 SUPERFAMILY SSF52540 17 198 3.42E-34 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14865 3480cd573d47a9957acf9fa3fe3f7b3c 210 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 10 193 7.1E-76 T 10-03-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 RG49_RS14865 3480cd573d47a9957acf9fa3fe3f7b3c 210 Gene3D G3DSA:3.40.50.300 6 198 1.8E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11570 aa2874f655af5247e303666bed22cea2 231 TIGRFAM TIGR00760 araD: L-ribulose-5-phosphate 4-epimerase 1 231 6.0E-136 T 10-03-2017 IPR004661 L-ribulose-5-phosphate 4-epimerase GO:0008270|GO:0008742|GO:0019572 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 RG49_RS11570 aa2874f655af5247e303666bed22cea2 231 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 196 1.2E-48 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS11570 aa2874f655af5247e303666bed22cea2 231 SUPERFAMILY SSF53639 1 223 6.28E-72 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS11570 aa2874f655af5247e303666bed22cea2 231 Gene3D G3DSA:3.40.225.10 2 231 7.4E-76 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS11570 aa2874f655af5247e303666bed22cea2 231 SMART SM01007 7 198 1.6E-72 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS11570 aa2874f655af5247e303666bed22cea2 231 Hamap MF_00989 L-ribulose-5-phosphate 4-epimerase [araD]. 1 231 76.813 T 10-03-2017 RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 SUPERFAMILY SSF46785 4 112 3.39E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.7E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.7E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.7E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 Gene3D G3DSA:3.40.190.10 178 265 7.4E-20 T 10-03-2017 RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 Gene3D G3DSA:1.10.10.10 4 88 1.5E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 Pfam PF03466 LysR substrate binding domain 91 291 4.1E-43 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 SUPERFAMILY SSF53850 92 296 9.96E-42 T 10-03-2017 RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 Gene3D G3DSA:3.40.190.10 92 177 1.7E-18 T 10-03-2017 RG49_RS07195 8bd02d7e2067704bed00d76c3daa39ec 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.3E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 Pfam PF08402 TOBE domain 283 355 3.1E-11 T 10-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 Pfam PF00005 ABC transporter 20 161 2.6E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 SUPERFAMILY SSF52540 4 243 3.64E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 SUPERFAMILY SSF50331 236 366 4.37E-32 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 Gene3D G3DSA:3.40.50.300 3 236 7.3E-77 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 Gene3D G3DSA:2.40.50.140 290 347 1.1E-28 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 SMART SM00382 28 211 2.8E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS13870 599aa7bb9acb7c8383cd6e9a94258fbf 371 Gene3D G3DSA:2.40.50.100 239 289 2.3E-23 T 10-03-2017 RG49_RS22290 196ac2b70de793f80a9d278a56ed753b 237 Pfam PF13942 YfhG lipoprotein 45 217 1.4E-75 T 10-03-2017 IPR025262 Quorum-sensing regulator protein G RG49_RS22290 196ac2b70de793f80a9d278a56ed753b 237 ProDom PD117379 LIPOPROTEIN YFHG HELIX ALPHA REGULATOR MEMBRANE TRANSCRIPTIONAL FAMILIIY EBP TWO-COMPONENT 27 218 5.0E-92 T 10-03-2017 RG49_RS16130 840515c41b977468e1fc4851c82a0f03 401 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 2 397 2.1E-205 T 10-03-2017 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 RG49_RS16130 840515c41b977468e1fc4851c82a0f03 401 Pfam PF03616 Sodium/glutamate symporter 2 366 1.6E-164 T 10-03-2017 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 RG49_RS22665 28faa2e57e32ec11f033df3893537d41 429 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 329 349 - T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS22665 28faa2e57e32ec11f033df3893537d41 429 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 405 9.3E-132 T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS22665 28faa2e57e32ec11f033df3893537d41 429 Pfam PF00860 Permease family 16 382 1.4E-108 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS24260 ca378b7f66bed154a8d0d51b494fd345 364 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 152 359 4.7E-41 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24260 ca378b7f66bed154a8d0d51b494fd345 364 Gene3D G3DSA:1.10.3720.10 131 351 3.9E-15 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24260 ca378b7f66bed154a8d0d51b494fd345 364 SUPERFAMILY SSF161098 131 345 1.7E-15 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16245 d5cbc44eff39aec46a54237c7b272acb 374 Pfam PF00534 Glycosyl transferases group 1 183 350 3.3E-39 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS16245 d5cbc44eff39aec46a54237c7b272acb 374 Pfam PF13439 Glycosyltransferase Family 4 13 173 7.4E-7 T 10-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 RG49_RS16245 d5cbc44eff39aec46a54237c7b272acb 374 SUPERFAMILY SSF53756 3 354 4.71E-63 T 10-03-2017 RG49_RS16245 d5cbc44eff39aec46a54237c7b272acb 374 Gene3D G3DSA:3.40.50.2000 155 349 6.5E-22 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 SUPERFAMILY SSF158544 215 266 2.22E-12 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 Gene3D G3DSA:1.10.40.60 215 284 2.0E-21 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 SUPERFAMILY SSF54523 285 321 3.82E-12 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 SUPERFAMILY SSF54523 36 101 3.82E-12 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 Gene3D G3DSA:1.10.40.60 100 213 8.2E-36 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 Pfam PF03934 Type II secretion system (T2SS), protein K 32 315 2.1E-66 T 10-03-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 Gene3D G3DSA:3.30.1300.30 31 99 7.2E-12 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 Gene3D G3DSA:3.30.1300.30 286 322 7.2E-12 T 10-03-2017 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 PIRSF PIRSF002786 1 327 1.6E-93 T 10-03-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 RG49_RS17945 37ea5be6c58fc9d5adc2e50992d58182 327 SUPERFAMILY SSF158544 103 212 8.11E-29 T 10-03-2017 RG49_RS09450 8250c4d04ec748a2ad004b06bd3804e8 427 SUPERFAMILY SSF51556 57 376 1.31E-108 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS09450 8250c4d04ec748a2ad004b06bd3804e8 427 Pfam PF07969 Amidohydrolase family 48 405 2.0E-56 T 10-03-2017 IPR013108 Amidohydrolase 3 RG49_RS09450 8250c4d04ec748a2ad004b06bd3804e8 427 Gene3D G3DSA:2.30.40.10 22 65 3.2E-6 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS09450 8250c4d04ec748a2ad004b06bd3804e8 427 Gene3D G3DSA:3.20.20.140 66 367 1.8E-126 T 10-03-2017 RG49_RS09450 8250c4d04ec748a2ad004b06bd3804e8 427 SUPERFAMILY SSF51338 6 65 3.65E-14 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Gene3D G3DSA:1.10.8.60 446 524 6.3E-20 T 10-03-2017 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 486 495 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 359 374 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 SMART SM00382 292 436 1.4E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Gene3D G3DSA:3.30.450.40 62 133 8.4E-4 T 10-03-2017 IPR029016 GAF domain-like RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Gene3D G3DSA:3.30.450.20 159 209 1.3E-7 T 10-03-2017 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Pfam PF00158 Sigma-54 interaction domain 272 440 2.1E-68 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Gene3D G3DSA:3.40.50.300 269 445 9.6E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 SUPERFAMILY SSF52540 272 511 4.84E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 SUPERFAMILY SSF46689 545 589 1.1E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 SMART SM00091 160 225 1.5E-4 T 10-03-2017 IPR000014 PAS domain RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 SUPERFAMILY SSF55785 161 207 4.71E-8 T 10-03-2017 IPR000014 PAS domain RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 296 309 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Pfam PF02954 Bacterial regulatory protein, Fis family 548 587 2.6E-13 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Pfam PF13188 PAS domain 162 208 4.8E-6 T 10-03-2017 IPR000014 PAS domain RG49_RS20565 9c2d8406cef9342b11256d8a7f47128d 592 Gene3D G3DSA:1.10.10.60 540 589 8.2E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14730 ffc43a48b7e5b704273e2729cf55af2a 329 Gene3D G3DSA:3.10.129.10 161 315 4.2E-65 T 10-03-2017 IPR029069 HotDog domain RG49_RS14730 ffc43a48b7e5b704273e2729cf55af2a 329 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 181 314 4.6E-49 T 10-03-2017 IPR012660 Thioesterase, putative RG49_RS14730 ffc43a48b7e5b704273e2729cf55af2a 329 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 174 313 5.9E-50 T 10-03-2017 IPR012660 Thioesterase, putative RG49_RS14730 ffc43a48b7e5b704273e2729cf55af2a 329 SUPERFAMILY SSF55729 15 162 1.69E-29 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS14730 ffc43a48b7e5b704273e2729cf55af2a 329 SUPERFAMILY SSF54637 171 313 8.25E-41 T 10-03-2017 IPR029069 HotDog domain RG49_RS14730 ffc43a48b7e5b704273e2729cf55af2a 329 Gene3D G3DSA:3.40.630.30 24 160 1.5E-26 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS14730 ffc43a48b7e5b704273e2729cf55af2a 329 Pfam PF13673 Acetyltransferase (GNAT) domain 56 145 5.2E-13 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 Gene3D G3DSA:1.10.10.10 4 82 1.2E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 SUPERFAMILY SSF53850 93 293 1.36E-43 T 10-03-2017 RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 Gene3D G3DSA:3.40.190.10 180 262 4.8E-23 T 10-03-2017 RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 Gene3D G3DSA:3.40.190.10 93 179 1.2E-16 T 10-03-2017 RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.6E-17 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 SUPERFAMILY SSF46785 4 114 2.45E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 Pfam PF03466 LysR substrate binding domain 92 293 8.1E-43 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.5E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.5E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20830 b1cff24eaec417b00e675d89b0a077cc 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.5E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 9 32 3.5E-8 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 PRINTS PR00813 Bacterial general secretion pathway protein G signature 49 67 3.5E-22 T 10-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 PRINTS PR00813 Bacterial general secretion pathway protein G signature 13 38 3.5E-22 T 10-03-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 13 146 1.1E-57 T 10-03-2017 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 SUPERFAMILY SSF54523 39 146 6.28E-40 T 10-03-2017 RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 Gene3D G3DSA:3.30.700.10 14 78 7.0E-9 T 10-03-2017 RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 Pfam PF08334 Type II secretion system (T2SS), protein G 36 145 2.0E-42 T 10-03-2017 IPR013545 Type II secretion system protein G RG49_RS20005 6206270ba912172db7ccef5a3637ea08 151 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 2.4E-8 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 84 6.8E-33 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 62 74 9.6E-23 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 9.6E-23 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 9.6E-23 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 44 60 9.6E-23 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 Pfam PF01455 HupF/HypC family 1 71 5.1E-26 T 10-03-2017 IPR001109 Hydrogenase expression/formation protein, HupF/HypC RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 SUPERFAMILY SSF159127 1 86 3.4E-28 T 10-03-2017 RG49_RS21435 9fdfbe7acb7e7284d80b63bbcc8ee1b2 90 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 10-03-2017 IPR019812 Hydrogenase assembly chaperone, conserved site RG49_RS08010 5ed61a173dbed387686c792682eea6c7 461 Pfam PF03606 C4-dicarboxylate anaerobic carrier 6 451 1.5E-134 T 10-03-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 RG49_RS08010 5ed61a173dbed387686c792682eea6c7 461 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 441 2.5E-197 T 10-03-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 RG49_RS02795 05d5865bf828d7eb92737185b81a72ef 408 Pfam PF00577 Outer membrane usher protein 1 320 2.7E-85 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS02795 05d5865bf828d7eb92737185b81a72ef 408 Pfam PF13953 PapC C-terminal domain 329 393 1.7E-22 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS08505 ca9ea4441a92c22b915ae0115633eb43 381 Pfam PF02595 Glycerate kinase family 3 373 1.2E-145 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS08505 ca9ea4441a92c22b915ae0115633eb43 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 6.7E-171 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS08505 ca9ea4441a92c22b915ae0115633eb43 381 Gene3D G3DSA:3.90.1510.10 42 275 4.0E-99 T 10-03-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 RG49_RS08505 ca9ea4441a92c22b915ae0115633eb43 381 SUPERFAMILY SSF110738 1 375 6.93E-136 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS08505 ca9ea4441a92c22b915ae0115633eb43 381 PIRSF PIRSF006078 1 376 6.0E-133 T 10-03-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 Gene3D G3DSA:3.30.70.610 377 434 6.7E-21 T 10-03-2017 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 Gene3D G3DSA:3.30.70.610 269 342 2.3E-25 T 10-03-2017 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 Gene3D G3DSA:3.30.465.10 107 268 6.1E-84 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 PIRSF PIRSF000101 4 569 0.0 T 10-03-2017 IPR012256 D-lactate dehydrogenase GO:0004457|GO:0005887|GO:0006089|GO:0050660|GO:0051287 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 SUPERFAMILY SSF55103 275 567 1.68E-118 T 10-03-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 Pfam PF01565 FAD binding domain 47 166 3.8E-8 T 10-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 Gene3D G3DSA:3.30.43.10 4 102 3.4E-9 T 10-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 SUPERFAMILY SSF56176 10 271 3.78E-74 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 Gene3D G3DSA:3.30.1370.20 435 519 3.4E-47 T 10-03-2017 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 RG49_RS24515 a5e840582b686cd8ce1e1d13ef92c2f3 571 Pfam PF09330 D-lactate dehydrogenase, membrane binding 278 567 7.1E-148 T 10-03-2017 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 RG49_RS02200 3151dcc4ad9a0449cb8eb68871986ac7 823 SUPERFAMILY SSF53098 642 816 3.1E-23 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS02200 3151dcc4ad9a0449cb8eb68871986ac7 823 Pfam PF16473 3' exoribonuclease, RNase T-like 642 813 4.6E-53 T 10-03-2017 IPR033390 3'-5' exoribonuclease Rv2179c-like domain RG49_RS02200 3151dcc4ad9a0449cb8eb68871986ac7 823 Gene3D G3DSA:3.30.420.10 643 814 3.9E-12 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 SMART SM00363 96 160 8.2E-21 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 SMART SM01390 3 95 1.3E-49 T 10-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 2.4E-87 T 10-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 10-03-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 1.0E-30 T 10-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 SUPERFAMILY SSF55174 3 206 1.96E-73 T 10-03-2017 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 Pfam PF01479 S4 domain 97 143 7.1E-19 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 Gene3D G3DSA:3.10.290.10 102 190 1.8E-33 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.44 T 10-03-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 RG49_RS18120 21ff7290df0255854c7a7e36a8c2ec66 206 Gene3D G3DSA:1.10.1050.10 1 101 2.9E-41 T 10-03-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 Pfam PF01019 Gamma-glutamyltranspeptidase 64 572 2.6E-192 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 49 571 3.6E-237 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 391 415 - T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 SUPERFAMILY SSF56235 41 572 5.21E-197 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 291 310 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 480 497 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 144 162 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 181 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 71 96 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 391 409 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 456 471 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 261 277 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS17345 1fbbb7f1657713c9deb4ed6f76bac1a9 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 415 433 2.7E-81 T 10-03-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 RG49_RS05580 bfbd420a3b0d77600aa5fd8fa6876f2d 354 SUPERFAMILY SSF52540 148 331 1.99E-31 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05580 bfbd420a3b0d77600aa5fd8fa6876f2d 354 Gene3D G3DSA:3.40.50.300 149 353 3.7E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05580 bfbd420a3b0d77600aa5fd8fa6876f2d 354 Pfam PF02562 PhoH-like protein 149 353 9.2E-76 T 10-03-2017 IPR003714 PhoH-like protein GO:0005524 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 Gene3D G3DSA:3.40.50.980 239 401 9.3E-41 T 10-03-2017 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 Gene3D G3DSA:3.30.300.30 477 574 6.7E-30 T 10-03-2017 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 Gene3D G3DSA:2.30.38.10 402 473 5.2E-31 T 10-03-2017 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 Pfam PF13193 AMP-binding enzyme C-terminal domain 491 565 2.9E-18 T 10-03-2017 IPR025110 AMP-binding enzyme C-terminal domain RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 Pfam PF00501 AMP-binding enzyme 51 482 3.3E-114 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 SUPERFAMILY SSF56801 34 577 7.06E-155 T 10-03-2017 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 Gene3D G3DSA:3.40.50.980 45 174 4.4E-43 T 10-03-2017 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 Gene3D G3DSA:3.40.50.980 207 238 4.4E-43 T 10-03-2017 RG49_RS00950 e6f6e79b8cc52b502130798eee308ebb 583 ProSitePatterns PS00455 Putative AMP-binding domain signature. 233 244 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PIRSF PIRSF002560 1 157 6.8E-72 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 157 1.6E-84 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 Pfam PF00210 Ferritin-like domain 8 144 7.8E-40 T 10-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PRINTS PR00601 Bacterioferritin signature 128 149 3.7E-77 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PRINTS PR00601 Bacterioferritin signature 44 64 3.7E-77 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PRINTS PR00601 Bacterioferritin signature 86 106 3.7E-77 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PRINTS PR00601 Bacterioferritin signature 3 22 3.7E-77 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PRINTS PR00601 Bacterioferritin signature 65 85 3.7E-77 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PRINTS PR00601 Bacterioferritin signature 107 127 3.7E-77 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 PRINTS PR00601 Bacterioferritin signature 23 43 3.7E-77 T 10-03-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 SUPERFAMILY SSF47240 1 157 1.35E-54 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS17925 41794e2f15274aa8e594ce47f97a857d 158 Gene3D G3DSA:1.20.1260.10 1 156 4.8E-67 T 10-03-2017 IPR012347 Ferritin-related RG49_RS06250 6eaa3a76c2e7f3668a7434cd0d3f6a23 208 Gene3D G3DSA:3.40.50.850 3 205 3.8E-48 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS06250 6eaa3a76c2e7f3668a7434cd0d3f6a23 208 Pfam PF00857 Isochorismatase family 14 165 4.3E-21 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS06250 6eaa3a76c2e7f3668a7434cd0d3f6a23 208 SUPERFAMILY SSF52499 3 202 2.35E-53 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS14790 8b1c27921ee7ac72a81e451463ba853a 461 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 70 97 - T 10-03-2017 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 RG49_RS14790 8b1c27921ee7ac72a81e451463ba853a 461 Pfam PF13347 MFS/sugar transport protein 21 444 3.0E-83 T 10-03-2017 RG49_RS14790 8b1c27921ee7ac72a81e451463ba853a 461 Gene3D G3DSA:1.20.1250.20 241 441 1.5E-14 T 10-03-2017 RG49_RS14790 8b1c27921ee7ac72a81e451463ba853a 461 Gene3D G3DSA:1.20.1250.20 35 210 1.1E-6 T 10-03-2017 RG49_RS14790 8b1c27921ee7ac72a81e451463ba853a 461 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 19 457 1.6E-161 T 10-03-2017 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 RG49_RS14790 8b1c27921ee7ac72a81e451463ba853a 461 SUPERFAMILY SSF103473 22 444 1.02E-31 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Pfam PF00703 Glycosyl hydrolases family 2 222 334 4.0E-14 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Pfam PF02929 Beta galactosidase small chain 754 1020 2.3E-60 T 10-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 SUPERFAMILY SSF49785 15 219 3.83E-70 T 10-03-2017 IPR008979 Galactose-binding domain-like RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Gene3D G3DSA:2.70.98.10 736 1021 5.3E-90 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Pfam PF16353 Domain of unknown function(DUF4981) 637 723 1.2E-18 T 10-03-2017 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 PRINTS PR00132 Glycosyl hydrolase family 2 signature 376 394 6.1E-39 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 PRINTS PR00132 Glycosyl hydrolase family 2 signature 448 463 6.1E-39 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 PRINTS PR00132 Glycosyl hydrolase family 2 signature 345 359 6.1E-39 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 PRINTS PR00132 Glycosyl hydrolase family 2 signature 532 547 6.1E-39 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 PRINTS PR00132 Glycosyl hydrolase family 2 signature 147 162 6.1E-39 T 10-03-2017 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Gene3D G3DSA:3.20.20.80 336 624 1.2E-116 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 336 629 2.6E-125 T 10-03-2017 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 52 219 1.4E-75 T 10-03-2017 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 386 411 - T 10-03-2017 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Gene3D G3DSA:2.60.40.320 626 728 1.8E-36 T 10-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Hamap MF_01687 Beta-galactosidase [lacZ]. 6 1024 17.744 T 10-03-2017 IPR023933 Glycoside hydrolase, family 2, beta-galactosidase GO:0016798 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 SUPERFAMILY SSF49303 622 727 1.77E-32 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Gene3D G3DSA:2.60.120.260 7 208 1.0E-88 T 10-03-2017 IPR008979 Galactose-binding domain-like RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 SUPERFAMILY SSF51445 335 625 1.75E-105 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 SUPERFAMILY SSF49303 221 334 6.33E-27 T 10-03-2017 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 448 462 - T 10-03-2017 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 SMART SM01038 749 1022 3.4E-117 T 10-03-2017 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 SUPERFAMILY SSF74650 734 1022 2.67E-95 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS09415 61d924523cd4bd0dbab1985e54f1f401 1024 Gene3D G3DSA:2.60.40.320 209 334 4.0E-33 T 10-03-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 RG49_RS18505 262797b7d64897722e53b0743f6d72d3 496 Pfam PF07690 Major Facilitator Superfamily 26 287 1.7E-24 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS18505 262797b7d64897722e53b0743f6d72d3 496 TIGRFAM TIGR00891 2A0112: MFS transporter, sialate:H+ symporter (SHS) family 9 442 2.7E-195 T 10-03-2017 IPR004742 Sialic acid transporter GO:0015144|GO:0016021|GO:0034219 RG49_RS18505 262797b7d64897722e53b0743f6d72d3 496 SUPERFAMILY SSF103473 267 452 3.53E-62 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS18505 262797b7d64897722e53b0743f6d72d3 496 SUPERFAMILY SSF103473 8 203 3.53E-62 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS18505 262797b7d64897722e53b0743f6d72d3 496 Gene3D G3DSA:1.20.1250.20 273 450 6.1E-16 T 10-03-2017 RG49_RS18505 262797b7d64897722e53b0743f6d72d3 496 Gene3D G3DSA:1.20.1250.20 17 202 2.4E-32 T 10-03-2017 RG49_RS18505 262797b7d64897722e53b0743f6d72d3 496 Hamap MF_01238 Putative sialic acid transporter [nanT]. 1 488 56.061 T 10-03-2017 IPR004742 Sialic acid transporter GO:0015144|GO:0016021|GO:0034219 RG49_RS01380 5c9e9fcaf450e96d87a02972c30b517c 286 Pfam PF03881 Fructosamine kinase 1 285 4.2E-114 T 10-03-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 RG49_RS01380 5c9e9fcaf450e96d87a02972c30b517c 286 Gene3D G3DSA:3.90.1200.10 96 259 3.5E-13 T 10-03-2017 RG49_RS01380 5c9e9fcaf450e96d87a02972c30b517c 286 SUPERFAMILY SSF56112 4 280 2.89E-41 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS01380 5c9e9fcaf450e96d87a02972c30b517c 286 Gene3D G3DSA:3.30.200.20 32 90 8.5E-5 T 10-03-2017 RG49_RS01380 5c9e9fcaf450e96d87a02972c30b517c 286 PIRSF PIRSF006221 1 286 2.4E-95 T 10-03-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 172 187 - T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 47 243 6.8E-95 T 10-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 Pfam PF00813 FliP family 48 239 1.6E-79 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 103 115 1.1E-33 T 10-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 165 177 1.1E-33 T 10-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 43 52 1.1E-33 T 10-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 1.1E-33 T 10-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 115 129 1.1E-33 T 10-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 233 243 1.1E-33 T 10-03-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 220 232 - T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 172 192 2.9E-68 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 64 84 2.9E-68 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 217 242 2.9E-68 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 45 64 2.9E-68 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 193 214 2.9E-68 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS00170 89f0dc879648d61192436e6e0cc93789 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 84 103 2.9E-68 T 10-03-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 RG49_RS17595 d928a525ef18cef8575bc86784347524 711 ProDom PD147088 MEMBRANE INNER TRANSMEMBRANE IGAA HOMOLOG DEHYDROGENASE GROWTH ATTENUATOR INTRACELLULAR GENOME 3 697 0.0 T 10-03-2017 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 RG49_RS17595 d928a525ef18cef8575bc86784347524 711 Pfam PF07095 Intracellular growth attenuator protein IgaA 1 703 0.0 T 10-03-2017 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 PIRSF PIRSF001267 1 494 8.2E-188 T 10-03-2017 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 Gene3D G3DSA:3.30.420.150 128 300 8.4E-52 T 10-03-2017 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 SUPERFAMILY SSF109604 307 493 6.75E-46 T 10-03-2017 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 Pfam PF02541 Ppx/GppA phosphatase family 21 301 3.5E-103 T 10-03-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 Hamap MF_01550 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [gppA]. 2 494 55.002 T 10-03-2017 IPR023709 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase GO:0008894|GO:0015974 KEGG: 00230+3.6.1.40 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 Gene3D G3DSA:3.30.420.40 4 127 2.7E-45 T 10-03-2017 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 SUPERFAMILY SSF53067 132 300 3.02E-41 T 10-03-2017 RG49_RS15325 e8cd8a2f797b8fd19ab9db0637c47d28 494 SUPERFAMILY SSF53067 7 128 2.43E-37 T 10-03-2017 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 Gene3D G3DSA:2.30.40.10 31 125 1.4E-15 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 Gene3D G3DSA:3.20.20.140 296 356 3.0E-7 T 10-03-2017 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 SUPERFAMILY SSF51556 85 333 6.57E-27 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 SUPERFAMILY SSF51338 333 354 2.38E-15 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 SUPERFAMILY SSF51338 22 85 2.38E-15 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 Pfam PF13382 Adenine deaminase C-terminal domain 434 579 6.3E-56 T 10-03-2017 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 Pfam PF01979 Amidohydrolase family 82 362 1.7E-28 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 Hamap MF_01518 Adenine deaminase [ade]. 31 583 35.921 T 10-03-2017 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 RG49_RS15925 11c506f1df10ee6588abb52a3bba1539 588 TIGRFAM TIGR01178 ade: adenine deaminase 31 584 1.2E-253 T 10-03-2017 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 RG49_RS05645 f32afda8bbffe3f14c1dd9b290121171 128 Pfam PF01042 Endoribonuclease L-PSP 13 125 1.4E-32 T 10-03-2017 IPR006175 YjgF/YER057c/UK114 family RG49_RS05645 f32afda8bbffe3f14c1dd9b290121171 128 TIGRFAM TIGR03610 RutC: pyrimidine utilization protein C 1 127 1.2E-75 T 10-03-2017 IPR019898 Putative aminoacrylate peracid reductase RutC RG49_RS05645 f32afda8bbffe3f14c1dd9b290121171 128 Gene3D G3DSA:3.30.1330.40 3 127 1.4E-32 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS05645 f32afda8bbffe3f14c1dd9b290121171 128 SUPERFAMILY SSF55298 3 126 3.93E-34 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS05645 f32afda8bbffe3f14c1dd9b290121171 128 Hamap MF_00831 Putative aminoacrylate peracid reductase RutC [rutC]. 1 128 44.886 T 10-03-2017 IPR019898 Putative aminoacrylate peracid reductase RutC RG49_RS05645 f32afda8bbffe3f14c1dd9b290121171 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 10-03-2017 IPR019897 RidA, conserved site RG49_RS15835 f307558a86aefc0bfcb976cd0d5b8f60 497 Gene3D G3DSA:3.40.720.10 2 354 3.0E-87 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS15835 f307558a86aefc0bfcb976cd0d5b8f60 497 Pfam PF16347 Domain of unknown function (DUF4976) 385 439 3.3E-7 T 10-03-2017 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 RG49_RS15835 f307558a86aefc0bfcb976cd0d5b8f60 497 Gene3D G3DSA:3.30.1120.10 373 453 1.2E-19 T 10-03-2017 RG49_RS15835 f307558a86aefc0bfcb976cd0d5b8f60 497 Pfam PF00884 Sulfatase 4 341 1.8E-80 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS15835 f307558a86aefc0bfcb976cd0d5b8f60 497 SUPERFAMILY SSF53649 2 440 2.75E-104 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS15835 f307558a86aefc0bfcb976cd0d5b8f60 497 ProSitePatterns PS00523 Sulfatases signature 1. 50 62 - T 10-03-2017 IPR024607 Sulfatase, conserved site RG49_RS15835 f307558a86aefc0bfcb976cd0d5b8f60 497 ProSitePatterns PS00149 Sulfatases signature 2. 92 102 - T 10-03-2017 IPR024607 Sulfatase, conserved site RG49_RS17175 de7db2d0f9ab1a946d51bc7ec8d5ac64 254 Gene3D G3DSA:3.40.50.300 5 242 2.2E-56 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17175 de7db2d0f9ab1a946d51bc7ec8d5ac64 254 Pfam PF00005 ABC transporter 20 168 2.0E-22 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17175 de7db2d0f9ab1a946d51bc7ec8d5ac64 254 TIGRFAM TIGR02770 nickel_nikD: nickel import ATP-binding protein NikD 18 245 1.7E-106 T 10-03-2017 IPR014138 Nickel import ATP-binding protein NikD GO:0005886|GO:0015413|GO:0015675|GO:0016151 RG49_RS17175 de7db2d0f9ab1a946d51bc7ec8d5ac64 254 SUPERFAMILY SSF52540 16 241 2.82E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17175 de7db2d0f9ab1a946d51bc7ec8d5ac64 254 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17175 de7db2d0f9ab1a946d51bc7ec8d5ac64 254 SMART SM00382 28 218 2.4E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS14940 96e1520725d626446d72e10993ed431a 181 SUPERFAMILY SSF52218 2 172 3.42E-30 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS14940 96e1520725d626446d72e10993ed431a 181 Gene3D G3DSA:3.40.50.360 2 73 8.5E-28 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS14940 96e1520725d626446d72e10993ed431a 181 Gene3D G3DSA:3.40.50.360 105 175 8.5E-28 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS14940 96e1520725d626446d72e10993ed431a 181 Pfam PF12724 Flavodoxin domain 4 152 1.7E-53 T 10-03-2017 IPR026816 Flavodoxin domain RG49_RS14940 96e1520725d626446d72e10993ed431a 181 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 10-03-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 SMART SM00421 135 192 5.6E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 1.2E-7 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 1.2E-7 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 1.2E-7 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 SUPERFAMILY SSF46894 126 186 8.5E-11 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 152 179 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 191 3.4E-19 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 Gene3D G3DSA:1.10.10.10 134 189 6.0E-10 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00155 14a5692a52dc0830278712e7f1d9210c 207 Hamap MF_00982 Transcriptional regulatory protein RcsA [rcsA]. 1 207 49.423 T 10-03-2017 IPR030866 Transcriptional regulatory protein RcsA GO:0006355 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 Pfam PF01266 FAD dependent oxidoreductase 5 323 4.9E-46 T 10-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 352 362 - T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 9 26 - T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 359 4.7E-28 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 27 4.7E-28 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 4.7E-28 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 78 90 4.7E-28 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 313 319 4.7E-28 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 4.7E-28 T 10-03-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 SUPERFAMILY SSF51905 312 374 5.18E-34 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 SUPERFAMILY SSF51905 1 260 5.18E-34 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 381 497 1.8E-12 T 10-03-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 Gene3D G3DSA:3.50.50.60 2 270 1.3E-38 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17440 2fb29250ca463e57e91ca70040b47bb5 501 SUPERFAMILY SSF54373 226 319 2.16E-6 T 10-03-2017 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 Gene3D G3DSA:3.30.450.20 256 371 3.9E-23 T 10-03-2017 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 SUPERFAMILY SSF47384 379 452 9.02E-17 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 SMART SM00387 495 602 8.1E-35 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 Gene3D G3DSA:1.10.287.130 382 439 1.7E-16 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 Gene3D G3DSA:3.30.565.10 440 603 4.0E-41 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 561 1.1E-17 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 1.1E-17 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 547 1.1E-17 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 1.1E-17 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 SUPERFAMILY SSF55874 443 602 1.83E-42 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 SMART SM00304 212 262 3.3E-4 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 Pfam PF00672 HAMP domain 193 259 5.5E-7 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 SUPERFAMILY SSF55785 253 367 9.77E-19 T 10-03-2017 IPR000014 PAS domain RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 SMART SM00091 262 329 1.3E-10 T 10-03-2017 IPR000014 PAS domain RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 265 379 1.5E-16 T 10-03-2017 IPR000014 PAS domain RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 SMART SM00388 388 453 4.8E-19 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 Pfam PF00512 His Kinase A (phospho-acceptor) domain 389 450 6.2E-17 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 Pfam PF00989 PAS fold 265 369 1.1E-21 T 10-03-2017 IPR013767 PAS fold GO:0006355 RG49_RS24015 484fcd946e3cdaadc28b6c7bf482785e 608 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 496 599 3.0E-20 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 3.2E-11 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 SUPERFAMILY SSF46785 7 78 4.62E-12 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 Gene3D G3DSA:1.20.120.530 80 219 9.3E-23 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 Gene3D G3DSA:1.10.10.10 5 74 2.5E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 SMART SM00345 16 74 3.3E-17 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 SUPERFAMILY SSF48008 81 216 2.04E-20 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 Pfam PF07729 FCD domain 85 209 8.7E-24 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS03140 f19f560a6118383b5f6b27ac4e6d867b 221 SMART SM00895 84 210 3.9E-14 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS04010 f54267821097bf2da5d53969cd3631b0 119 Pfam PF04024 PspC domain 8 65 2.7E-15 T 10-03-2017 IPR007168 Phage shock protein, PspC, N-terminal RG49_RS04010 f54267821097bf2da5d53969cd3631b0 119 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 7 119 2.4E-40 T 10-03-2017 IPR014320 Phage shock protein, PspC RG49_RS17675 22d4fdace6dc4dee018a45c5c9b5d5b7 301 SUPERFAMILY SSF53850 74 301 3.52E-82 T 10-03-2017 RG49_RS17675 22d4fdace6dc4dee018a45c5c9b5d5b7 301 Gene3D G3DSA:3.40.190.10 76 208 3.0E-66 T 10-03-2017 RG49_RS17675 22d4fdace6dc4dee018a45c5c9b5d5b7 301 Pfam PF14502 Helix-turn-helix domain 24 71 1.6E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17675 22d4fdace6dc4dee018a45c5c9b5d5b7 301 Gene3D G3DSA:1.10.10.10 25 75 5.6E-6 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17675 22d4fdace6dc4dee018a45c5c9b5d5b7 301 Pfam PF14503 YhfZ C-terminal domain 75 301 3.1E-84 T 10-03-2017 IPR032791 Uncharacterised protein YhfZ, C-terminal domain RG49_RS24075 a7711d683a94332a7b9c18437bf8a79a 548 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 31 518 4.3E-240 T 10-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 RG49_RS24075 a7711d683a94332a7b9c18437bf8a79a 548 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 32 516 3.1E-216 T 10-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 RG49_RS24075 a7711d683a94332a7b9c18437bf8a79a 548 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 28 518 55.5 T 10-03-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 RG49_RS24075 a7711d683a94332a7b9c18437bf8a79a 548 SUPERFAMILY SSF51905 28 91 5.92E-26 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS24075 a7711d683a94332a7b9c18437bf8a79a 548 SUPERFAMILY SSF51905 144 358 5.92E-26 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS24075 a7711d683a94332a7b9c18437bf8a79a 548 Gene3D G3DSA:3.50.50.60 173 357 5.1E-25 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS24075 a7711d683a94332a7b9c18437bf8a79a 548 Gene3D G3DSA:3.50.50.60 30 98 5.1E-25 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 SMART SM01359 758 906 4.5E-34 T 10-03-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 759 906 5.0E-12 T 10-03-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 Pfam PF00207 Alpha-2-macroglobulin family 977 1056 9.4E-8 T 10-03-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 SUPERFAMILY SSF48239 1177 1434 7.07E-44 T 10-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 PIRSF PIRSF038980 1 1653 0.0 T 10-03-2017 IPR026284 Alpha-2-macroglobulin domain protein, bacteria RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 SMART SM01360 968 1057 4.5E-20 T 10-03-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 Gene3D G3DSA:1.50.10.20 1175 1434 5.2E-38 T 10-03-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 Pfam PF01835 MG2 domain 388 479 1.6E-20 T 10-03-2017 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 RG49_RS22470 25ae033e2512dc77834e7f535a1abeae 1653 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 289 381 7.2E-22 T 10-03-2017 IPR021868 Alpha-2-macroglobulin MG1 domain RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 SUPERFAMILY SSF103190 52 178 1.29E-33 T 10-03-2017 IPR029151 Periplasmic sensor domain-like RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 SMART SM00387 428 541 3.0E-22 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 539 7.3E-15 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 SUPERFAMILY SSF55785 223 277 3.84E-8 T 10-03-2017 IPR000014 PAS domain RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 330 373 8.1E-8 T 10-03-2017 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Gene3D G3DSA:3.30.450.20 43 179 7.9E-47 T 10-03-2017 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Gene3D G3DSA:1.10.287.130 318 387 6.5E-25 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 519 9.9E-9 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 497 9.9E-9 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 483 9.9E-9 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 538 9.9E-9 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 SMART SM00091 222 292 9.6E-9 T 10-03-2017 IPR000014 PAS domain RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 SUPERFAMILY SSF55874 409 546 9.17E-25 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Pfam PF00989 PAS fold 225 285 3.9E-5 T 10-03-2017 IPR013767 PAS fold GO:0006355 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Gene3D G3DSA:3.30.565.10 423 542 7.5E-24 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Pfam PF17203 Single cache domain 3 61 173 8.2E-22 T 10-03-2017 IPR033463 Single cache domain 3 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 SUPERFAMILY SSF55890 332 376 3.4E-8 T 10-03-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 RG49_RS08020 a82620900e0ab8560551efdee04c8fe1 552 Gene3D G3DSA:3.30.450.20 223 288 2.0E-7 T 10-03-2017 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 SUPERFAMILY SSF55347 154 308 6.03E-49 T 10-03-2017 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 SUPERFAMILY SSF51735 1 170 4.19E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 Gene3D G3DSA:3.30.360.10 163 308 8.0E-48 T 10-03-2017 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 333 1.2E-124 T 10-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 Gene3D G3DSA:3.40.50.720 1 162 4.0E-62 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 146 2.8E-32 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 334 38.071 T 10-03-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 SMART SM00859 3 146 9.6E-53 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 149 165 - T 10-03-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS14320 99df47b2c81f0a19e7dd48fb7698fdd6 334 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 163 311 5.4E-20 T 10-03-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 Pfam PF03441 FAD binding domain of DNA photolyase 272 466 2.9E-85 T 10-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 SUPERFAMILY SSF48173 192 470 9.68E-108 T 10-03-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 Gene3D G3DSA:1.25.40.80 148 283 4.1E-42 T 10-03-2017 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 SUPERFAMILY SSF52425 3 198 9.81E-53 T 10-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 Gene3D G3DSA:1.10.579.10 284 469 1.3E-80 T 10-03-2017 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 322 334 - T 10-03-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 PRINTS PR00147 DNA photolyase signature 322 338 1.6E-32 T 10-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 PRINTS PR00147 DNA photolyase signature 381 395 1.6E-32 T 10-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 PRINTS PR00147 DNA photolyase signature 342 360 1.6E-32 T 10-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 PRINTS PR00147 DNA photolyase signature 143 159 1.6E-32 T 10-03-2017 IPR002081 Cryptochrome/DNA photolyase class 1 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 Pfam PF00875 DNA photolyase 5 168 1.6E-46 T 10-03-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 342 361 - T 10-03-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal RG49_RS07550 1a457997956b059da1d65aa62df36f64 472 Gene3D G3DSA:3.40.50.620 2 147 1.8E-46 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 PIRSF PIRSF000164 11 336 9.4E-97 T 10-03-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 SUPERFAMILY SSF51395 1 334 7.69E-104 T 10-03-2017 RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 10-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 336 1.6E-168 T 10-03-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 Pfam PF01180 Dihydroorotate dehydrogenase 47 335 3.7E-92 T 10-03-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 Gene3D G3DSA:3.20.20.70 1 335 4.7E-125 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 336 51.056 T 10-03-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS05995 b67f2657a8e1d9fbf72ecf5cba7ecdd5 336 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 292 312 - T 10-03-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 RG49_RS21660 29920038b47c3570580a45919f232718 512 Gene3D G3DSA:1.20.1250.20 16 199 4.0E-32 T 10-03-2017 RG49_RS21660 29920038b47c3570580a45919f232718 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 498 4.8E-220 T 10-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 RG49_RS21660 29920038b47c3570580a45919f232718 512 Pfam PF07690 Major Facilitator Superfamily 19 413 1.5E-53 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS21660 29920038b47c3570580a45919f232718 512 Gene3D G3DSA:1.20.1250.20 476 501 1.1E-22 T 10-03-2017 RG49_RS21660 29920038b47c3570580a45919f232718 512 Gene3D G3DSA:1.20.1250.20 266 424 1.1E-22 T 10-03-2017 RG49_RS21660 29920038b47c3570580a45919f232718 512 SUPERFAMILY SSF103473 475 500 4.71E-71 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS21660 29920038b47c3570580a45919f232718 512 SUPERFAMILY SSF103473 9 196 4.71E-71 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS21660 29920038b47c3570580a45919f232718 512 SUPERFAMILY SSF103473 251 423 4.71E-71 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS00695 761d1d05f18fac9c0e78208fd8a3f517 118 Hamap MF_01435 Protein YebF [yebF]. 1 118 37.737 T 10-03-2017 IPR020236 Uncharacterised protein family YebF RG49_RS00695 761d1d05f18fac9c0e78208fd8a3f517 118 Pfam PF13995 YebF-like protein 28 116 1.5E-40 T 10-03-2017 IPR025603 YebF/Colicin-M immunity protein RG49_RS00695 761d1d05f18fac9c0e78208fd8a3f517 118 ProDom PD077599 YEBF LIPOPROTEIN EXPORTED PERIPLASMIC PRECURSOR SIGNAL SIMILAR PALMITATE MEMBRANE ESCHERICHIA 20 118 3.0E-53 T 10-03-2017 IPR025603 YebF/Colicin-M immunity protein RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 SUPERFAMILY SSF51735 3 164 3.74E-52 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 Gene3D G3DSA:3.40.50.720 1 165 1.4E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 Pfam PF02056 Family 4 glycosyl hydrolase 6 184 5.1E-66 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 10-03-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 Gene3D G3DSA:3.90.110.10 167 200 6.0E-21 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 1.5E-58 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 1.5E-58 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 1.5E-58 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 1.5E-58 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 1.5E-58 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 1.5E-58 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 1.5E-58 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS15815 90ed12546fc5b7cd61bc0b0cf28c5225 212 SUPERFAMILY SSF56327 168 201 1.19E-6 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS06675 92818a5a8927573f060d7f0a87ff7165 352 Pfam PF05125 Phage major capsid protein, P2 family 9 338 4.2E-149 T 10-03-2017 IPR006441 Bacteriophage P2, GpN, major capsid GO:0019028 RG49_RS06675 92818a5a8927573f060d7f0a87ff7165 352 TIGRFAM TIGR01551 major_capsid_P2: phage major capsid protein, P2 family 7 340 3.7E-99 T 10-03-2017 IPR006441 Bacteriophage P2, GpN, major capsid GO:0019028 RG49_RS00815 c168a96fc2b78c20ab1753ca8b0df6f1 263 Gene3D G3DSA:3.30.450.40 86 261 1.1E-70 T 10-03-2017 IPR029016 GAF domain-like RG49_RS00815 c168a96fc2b78c20ab1753ca8b0df6f1 263 Pfam PF01614 Bacterial transcriptional regulator 129 254 1.3E-48 T 10-03-2017 IPR014757 Transcription regulator IclR, C-terminal RG49_RS00815 c168a96fc2b78c20ab1753ca8b0df6f1 263 SMART SM00346 13 102 8.0E-36 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS00815 c168a96fc2b78c20ab1753ca8b0df6f1 263 Gene3D G3DSA:1.10.10.10 12 85 1.0E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00815 c168a96fc2b78c20ab1753ca8b0df6f1 263 SUPERFAMILY SSF55781 77 259 5.23E-56 T 10-03-2017 IPR029016 GAF domain-like RG49_RS00815 c168a96fc2b78c20ab1753ca8b0df6f1 263 SUPERFAMILY SSF46785 13 86 1.43E-15 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00815 c168a96fc2b78c20ab1753ca8b0df6f1 263 Pfam PF09339 IclR helix-turn-helix domain 15 65 2.2E-13 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS25370 11795cf04a5c92ff2bc67f9e7e0f4257 350 Gene3D G3DSA:3.40.50.2000 204 320 3.0E-16 T 10-03-2017 RG49_RS25370 11795cf04a5c92ff2bc67f9e7e0f4257 350 SUPERFAMILY SSF53756 30 349 2.2E-34 T 10-03-2017 RG49_RS25370 11795cf04a5c92ff2bc67f9e7e0f4257 350 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 180 320 2.3E-7 T 10-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 RG49_RS21310 1086d0197327cf387ccba41b7da9b310 302 PIRSF PIRSF002936 1 302 8.0E-156 T 10-03-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 RG49_RS21310 1086d0197327cf387ccba41b7da9b310 302 SUPERFAMILY SSF52402 5 209 1.3E-75 T 10-03-2017 RG49_RS21310 1086d0197327cf387ccba41b7da9b310 302 Gene3D G3DSA:3.40.50.620 2 210 1.9E-64 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS21310 1086d0197327cf387ccba41b7da9b310 302 Gene3D G3DSA:3.40.50.620 244 253 1.9E-64 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS21310 1086d0197327cf387ccba41b7da9b310 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 29 257 1.2E-66 T 10-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 RG49_RS21310 1086d0197327cf387ccba41b7da9b310 302 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 4 302 59.643 T 10-03-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 RG49_RS21310 1086d0197327cf387ccba41b7da9b310 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 9 302 2.0E-169 T 10-03-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 RG49_RS21835 50b6b5c27931a05bc2f3a432a0e36708 69 SUPERFAMILY SSF53041 3 49 2.75E-8 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS21835 50b6b5c27931a05bc2f3a432a0e36708 69 Gene3D G3DSA:3.40.50.1390 3 48 4.0E-7 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS21835 50b6b5c27931a05bc2f3a432a0e36708 69 Pfam PF00239 Resolvase, N terminal domain 5 46 2.7E-6 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 23 242 2.9E-67 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 Gene3D G3DSA:3.40.190.10 20 108 1.1E-44 T 10-03-2017 RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 Gene3D G3DSA:3.40.190.10 203 242 1.1E-44 T 10-03-2017 RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 Gene3D G3DSA:3.40.190.10 110 201 1.9E-28 T 10-03-2017 RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 2 241 1.5E-92 T 10-03-2017 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 SUPERFAMILY SSF53850 1 242 7.65E-72 T 10-03-2017 RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 SMART SM00079 22 243 5.8E-4 T 10-03-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 SMART SM00062 22 243 9.7E-86 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS06445 8dada9975a23ec7b183368bc56ba560f 243 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 45 58 - T 10-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 RG49_RS15615 38e4735f6a4e58ce3f0f685a3f6355da 121 SUPERFAMILY SSF56935 2 121 9.16E-32 T 10-03-2017 RG49_RS15615 38e4735f6a4e58ce3f0f685a3f6355da 121 Gene3D G3DSA:2.40.170.10 1 121 4.1E-36 T 10-03-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 RG49_RS15615 38e4735f6a4e58ce3f0f685a3f6355da 121 Pfam PF02264 LamB porin 10 121 3.6E-28 T 10-03-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 RG49_RS15615 38e4735f6a4e58ce3f0f685a3f6355da 121 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 1 116 2.0E-63 T 10-03-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 RG49_RS13620 cdffe7c4b30e2ac7c4f575744156ead2 198 SMART SM00028 73 106 0.0061 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS13620 cdffe7c4b30e2ac7c4f575744156ead2 198 SMART SM00028 144 177 25.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS13620 cdffe7c4b30e2ac7c4f575744156ead2 198 Gene3D G3DSA:1.25.40.10 66 111 2.1E-8 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS13620 cdffe7c4b30e2ac7c4f575744156ead2 198 SUPERFAMILY SSF48452 62 175 6.45E-15 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS13620 cdffe7c4b30e2ac7c4f575744156ead2 198 Gene3D G3DSA:1.25.40.10 112 193 6.7E-35 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS23040 eee28c230b565de59322e7a02f56dcc3 169 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 23 143 4.0E-51 T 10-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 RG49_RS23040 eee28c230b565de59322e7a02f56dcc3 169 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 22 146 3.9E-49 T 10-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 RG49_RS23040 eee28c230b565de59322e7a02f56dcc3 169 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 85 97 - T 10-03-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 RG49_RS23040 eee28c230b565de59322e7a02f56dcc3 169 Gene3D G3DSA:2.70.70.10 14 167 1.8E-60 T 10-03-2017 RG49_RS23040 eee28c230b565de59322e7a02f56dcc3 169 SUPERFAMILY SSF51261 12 167 4.36E-56 T 10-03-2017 IPR011055 Duplicated hybrid motif RG49_RS11520 5e2d35a8b13af904029fef3ca1c47da3 551 Pfam PF12793 Sugar transport-related sRNA regulator N-term 5 118 2.6E-42 T 10-03-2017 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain RG49_RS11520 5e2d35a8b13af904029fef3ca1c47da3 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 165 306 4.8E-19 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS11520 5e2d35a8b13af904029fef3ca1c47da3 551 SUPERFAMILY SSF53850 121 546 1.99E-66 T 10-03-2017 RG49_RS11520 5e2d35a8b13af904029fef3ca1c47da3 551 Gene3D G3DSA:3.90.76.10 133 266 5.0E-23 T 10-03-2017 RG49_RS11520 5e2d35a8b13af904029fef3ca1c47da3 551 Gene3D G3DSA:1.10.10.10 22 94 9.3E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS11520 5e2d35a8b13af904029fef3ca1c47da3 551 Gene3D G3DSA:3.40.190.10 267 308 8.7E-6 T 10-03-2017 RG49_RS11520 5e2d35a8b13af904029fef3ca1c47da3 551 Hamap MF_01449 HTH-type transcriptional regulator SgrR [sgrR]. 1 551 67.078 T 10-03-2017 IPR023767 Transcriptional regulator SgrR RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 SUPERFAMILY SSF52009 236 355 1.23E-24 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 559 574 3.2E-20 T 10-03-2017 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 612 624 3.2E-20 T 10-03-2017 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 576 591 3.2E-20 T 10-03-2017 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 405 424 3.2E-20 T 10-03-2017 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 SUPERFAMILY SSF55594 5 89 1.96E-16 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Gene3D G3DSA:3.30.1340.10 6 89 1.1E-19 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 559 577 - T 10-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 SUPERFAMILY SSF55804 689 828 1.22E-29 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Gene3D G3DSA:3.20.20.60 370 680 2.8E-102 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 296 307 - T 10-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Gene3D G3DSA:1.10.274.10 149 244 1.1E-16 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 SUPERFAMILY SSF51621 366 661 8.9E-98 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Gene3D G3DSA:3.40.930.10 688 830 6.3E-41 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Pfam PF05524 PEP-utilising enzyme, N-terminal 143 237 3.3E-10 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 10-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 689 829 8.1E-31 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 SUPERFAMILY SSF47831 147 254 1.14E-17 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 363 653 4.7E-114 T 10-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Pfam PF00391 PEP-utilising enzyme, mobile domain 264 337 1.7E-15 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Pfam PF00381 PTS HPr component phosphorylation site 7 84 1.2E-11 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 181 677 1.3E-144 T 10-03-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 RG49_RS14380 730816019363625b8f519d0774d7f3e3 833 Gene3D G3DSA:3.50.30.10 245 365 2.1E-30 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS23580 14c9362f4db222bfc2408592df2a27cc 183 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 169 2.9E-52 T 10-03-2017 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 RG49_RS23580 14c9362f4db222bfc2408592df2a27cc 183 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 161 5.1E-26 T 10-03-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 RG49_RS23580 14c9362f4db222bfc2408592df2a27cc 183 SUPERFAMILY SSF56300 1 163 2.02E-39 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS23580 14c9362f4db222bfc2408592df2a27cc 183 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 120 144 - T 10-03-2017 IPR020935 Phosphodiesterase YfcE, conserved site RG49_RS23580 14c9362f4db222bfc2408592df2a27cc 183 Gene3D G3DSA:3.60.21.10 1 163 2.4E-49 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 455 5.2E-208 T 10-03-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Gene3D G3DSA:2.160.10.10 245 324 8.1E-19 T 10-03-2017 RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 5 452 43.135 T 10-03-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 SUPERFAMILY SSF53448 5 252 9.6E-67 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Gene3D G3DSA:3.90.550.10 3 244 4.2E-71 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Gene3D G3DSA:2.160.10.10 325 455 6.8E-34 T 10-03-2017 RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 SUPERFAMILY SSF51161 255 438 2.62E-51 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Pfam PF12804 MobA-like NTP transferase domain 8 122 3.2E-20 T 10-03-2017 IPR025877 MobA-like NTP transferase RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 429 1.2E-7 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 353 382 0.0029 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS15560 17be33986353f1d5490ae097345f8a99 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 300 5.9E-6 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 811 886 1.5E-9 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 333 1.0E-6 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 313 325 - T 10-03-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Pfam PF07724 AAA domain (Cdc48 subfamily) 644 805 1.8E-37 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 679 697 - T 10-03-2017 IPR028299 ClpA/B, conserved site 2 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 SUPERFAMILY SSF52540 180 503 1.25E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Gene3D G3DSA:1.10.1780.10 17 150 2.3E-14 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 723 741 3.0E-29 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 694 712 3.0E-29 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 756 770 3.0E-29 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 3.0E-29 T 10-03-2017 IPR001270 ClpA/B family GO:0005524 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 SUPERFAMILY SSF52540 594 889 4.83E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 16 895 0.0 T 10-03-2017 IPR017729 Type VI secretion system, ATPase ClpV1 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 SUPERFAMILY SSF81923 16 124 8.63E-10 T 10-03-2017 IPR004176 Clp, N-terminal GO:0019538 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Gene3D G3DSA:1.10.8.60 364 446 2.2E-28 T 10-03-2017 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Gene3D G3DSA:3.40.50.300 605 819 6.8E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Gene3D G3DSA:1.10.8.60 820 896 1.3E-7 T 10-03-2017 RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 SMART SM01086 811 903 3.2E-6 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 Gene3D G3DSA:3.40.50.300 181 360 5.7E-38 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 SMART SM00382 645 793 2.2E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS10680 4fe86f06e26570f2033c8586d54a3db5 921 SMART SM00382 217 362 6.7E-9 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 10-03-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 366 9.4E-33 T 10-03-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 445 47.836 T 10-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 136 3.0E-45 T 10-03-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 443 1.2E-197 T 10-03-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 SUPERFAMILY SSF53738 2 181 1.41E-48 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Gene3D G3DSA:3.40.120.10 4 151 6.8E-47 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 SUPERFAMILY SSF53738 258 365 2.28E-31 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 442 2.4E-15 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 8.2E-15 T 10-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 8.2E-15 T 10-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 8.2E-15 T 10-03-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 3.5E-21 T 10-03-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Gene3D G3DSA:3.40.120.10 176 250 5.1E-27 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Gene3D G3DSA:3.30.310.50 359 443 1.2E-16 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 SUPERFAMILY SSF55957 357 444 8.89E-22 T 10-03-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 Gene3D G3DSA:3.40.120.10 251 358 2.1E-33 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS18760 a48afbb2e862540610188d89fb0f7d0e 445 SUPERFAMILY SSF53738 156 256 3.49E-30 T 10-03-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 Pfam PF01145 SPFH domain / Band 7 family 99 270 1.0E-31 T 10-03-2017 IPR001107 Band 7 domain RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 SMART SM00244 95 255 4.6E-44 T 10-03-2017 IPR001107 Band 7 domain RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 PRINTS PR00721 Stomatin signature 102 124 1.3E-6 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 PRINTS PR00721 Stomatin signature 184 201 1.3E-6 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 PRINTS PR00721 Stomatin signature 149 170 1.3E-6 T 10-03-2017 IPR001972 Stomatin family GO:0016020 RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 Pfam PF12221 Bacterial membrane protein N terminal 1 59 6.2E-15 T 10-03-2017 IPR020980 Menbrane protein HflK, N-terminal RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 SUPERFAMILY SSF117892 128 259 9.42E-21 T 10-03-2017 IPR001107 Band 7 domain RG49_RS13045 60c206983ae8a7d22f231b3be2428ec9 419 TIGRFAM TIGR01933 hflK: HflK protein 97 356 2.2E-125 T 10-03-2017 IPR010201 HflK GO:0016021 RG49_RS19450 e933f38c54e844615df09466b8372c27 122 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 1.8E-27 T 10-03-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS19450 e933f38c54e844615df09466b8372c27 122 TIGRFAM TIGR00526 folB_dom: FolB domain 1 118 5.5E-42 T 10-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS19450 e933f38c54e844615df09466b8372c27 122 Gene3D G3DSA:3.30.1130.10 1 115 5.8E-43 T 10-03-2017 RG49_RS19450 e933f38c54e844615df09466b8372c27 122 SUPERFAMILY SSF55620 1 115 4.45E-36 T 10-03-2017 RG49_RS19450 e933f38c54e844615df09466b8372c27 122 SMART SM00905 4 114 5.9E-46 T 10-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS19450 e933f38c54e844615df09466b8372c27 122 Pfam PF02152 Dihydroneopterin aldolase 4 113 5.1E-32 T 10-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS02960 0ef5fe073a18ffe29165fe9bf865a23a 217 Gene3D G3DSA:1.20.950.20 1 215 1.9E-75 T 10-03-2017 RG49_RS02960 0ef5fe073a18ffe29165fe9bf865a23a 217 Pfam PF01292 Prokaryotic cytochrome b561 13 186 2.5E-18 T 10-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 RG49_RS02960 0ef5fe073a18ffe29165fe9bf865a23a 217 SUPERFAMILY SSF81342 3 212 2.43E-54 T 10-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 RG49_RS02960 0ef5fe073a18ffe29165fe9bf865a23a 217 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 7 206 4.9E-69 T 10-03-2017 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 RG49_RS23470 4c66643224ab6b7ae9b969bf90adebdb 392 SUPERFAMILY SSF103473 14 391 2.75E-52 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23470 4c66643224ab6b7ae9b969bf90adebdb 392 Hamap MF_01118 UPF0226 membrane protein . 1 392 30.465 T 10-03-2017 IPR023008 Uncharacterised protein family UPF0226, major facilitator superfamily RG49_RS23470 4c66643224ab6b7ae9b969bf90adebdb 392 Pfam PF07690 Major Facilitator Superfamily 20 242 1.6E-16 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS23470 4c66643224ab6b7ae9b969bf90adebdb 392 Gene3D G3DSA:1.20.1250.20 17 197 7.9E-19 T 10-03-2017 RG49_RS23470 4c66643224ab6b7ae9b969bf90adebdb 392 Gene3D G3DSA:1.20.1250.20 221 388 4.7E-21 T 10-03-2017 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 Pfam PF00294 pfkB family carbohydrate kinase 6 297 3.6E-78 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 SUPERFAMILY SSF53613 7 307 4.21E-86 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 PRINTS PR00990 Ribokinase signature 36 55 9.0E-38 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 PRINTS PR00990 Ribokinase signature 220 231 9.0E-38 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 PRINTS PR00990 Ribokinase signature 9 30 9.0E-38 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 PRINTS PR00990 Ribokinase signature 108 121 9.0E-38 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 PRINTS PR00990 Ribokinase signature 176 191 9.0E-38 T 10-03-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 Gene3D G3DSA:3.40.1190.20 7 307 3.9E-98 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 Hamap MF_01987 Ribokinase [rbsK]. 5 304 26.144 T 10-03-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 RG49_RS15450 41d734846aafe532ef6a0c049f152afd 309 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 8 302 1.5E-108 T 10-03-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 RG49_RS19240 26f62221a6442baea7a00bca6226347d 472 SUPERFAMILY SSF103473 42 452 2.62E-81 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS19240 26f62221a6442baea7a00bca6226347d 472 Pfam PF07690 Major Facilitator Superfamily 56 327 3.2E-47 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS19240 26f62221a6442baea7a00bca6226347d 472 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 57 451 2.8E-128 T 10-03-2017 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS19240 26f62221a6442baea7a00bca6226347d 472 Gene3D G3DSA:1.20.1250.20 257 457 4.9E-21 T 10-03-2017 RG49_RS19240 26f62221a6442baea7a00bca6226347d 472 Gene3D G3DSA:1.20.1250.20 47 239 3.0E-44 T 10-03-2017 RG49_RS17655 ad64cec4eb7f19a532f05cb4e3f501d8 225 SUPERFAMILY SSF51366 3 218 1.04E-76 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS17655 ad64cec4eb7f19a532f05cb4e3f501d8 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 1.9E-96 T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS17655 ad64cec4eb7f19a532f05cb4e3f501d8 225 Gene3D G3DSA:3.20.20.70 1 221 6.3E-95 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS17655 ad64cec4eb7f19a532f05cb4e3f501d8 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS17655 ad64cec4eb7f19a532f05cb4e3f501d8 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 7.5E-92 T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS17655 ad64cec4eb7f19a532f05cb4e3f501d8 225 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS17655 ad64cec4eb7f19a532f05cb4e3f501d8 225 PIRSF PIRSF001461 1 225 7.8E-107 T 10-03-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 SUPERFAMILY SSF103491 16 424 4.18E-134 T 10-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 429 1.3E-141 T 10-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 10-03-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PIRSF PIRSF004557 11 441 4.2E-124 T 10-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 Pfam PF00344 SecY translocase 76 417 4.9E-120 T 10-03-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 Gene3D G3DSA:1.10.3370.10 17 437 1.5E-167 T 10-03-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 10 433 30.039 T 10-03-2017 IPR026593 Protein translocase subunit SecY RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 7.7E-99 T 10-03-2017 RG49_RS18100 4cd214bd2268cc5ab7f4398b9cbc6ce0 443 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 10-03-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 RG49_RS13125 a79f8c7aa6a157eb110797bca4970774 104 ProDom PD069399 MEMBRANE INNER YJEO SIMILAR INTEGRAL ORF22 ESCHERICHIA TRANSMEMBRANE COLI 12 103 5.0E-39 T 10-03-2017 IPR022553 Protein of unknown function DUF2645 RG49_RS13125 a79f8c7aa6a157eb110797bca4970774 104 Pfam PF10840 Protein of unknown function (DUF2645) 7 103 1.1E-37 T 10-03-2017 IPR022553 Protein of unknown function DUF2645 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 3.2E-11 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 3.2E-11 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 245 3.2E-11 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 Gene3D G3DSA:3.40.50.880 154 378 3.8E-85 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 SUPERFAMILY SSF52021 3 143 2.09E-57 T 10-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 SMART SM01097 3 133 2.9E-91 T 10-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 Gene3D G3DSA:3.50.30.20 4 146 1.7E-63 T 10-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 375 7.5E-153 T 10-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 Pfam PF00117 Glutamine amidotransferase class-I 197 372 1.7E-50 T 10-03-2017 IPR017926 Glutamine amidotransferase RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00097 Anthranilate synthase component II signature 264 275 1.1E-5 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00097 Anthranilate synthase component II signature 236 245 1.1E-5 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00097 Anthranilate synthase component II signature 349 362 1.1E-5 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 378 48.642 T 10-03-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 2.2E-52 T 10-03-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 SUPERFAMILY SSF52317 153 378 2.14E-64 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 233 247 2.5E-40 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 2.5E-40 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 2.5E-40 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 2.5E-40 T 10-03-2017 RG49_RS11710 3e3c113b99b2d0b1b74f7ef1690b4ff6 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 194 208 2.5E-40 T 10-03-2017 RG49_RS08145 e9b407cd402ef39d77772a144291a64a 137 Gene3D G3DSA:3.10.129.10 1 136 1.7E-49 T 10-03-2017 IPR029069 HotDog domain RG49_RS08145 e9b407cd402ef39d77772a144291a64a 137 Hamap MF_00907 Proofreading thioesterase EntH [entH]. 1 137 53.774 T 10-03-2017 IPR026576 Proofreading thioesterase EntH GO:0009239|GO:0016790 RG49_RS08145 e9b407cd402ef39d77772a144291a64a 137 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 134 1.3E-47 T 10-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 RG49_RS08145 e9b407cd402ef39d77772a144291a64a 137 SUPERFAMILY SSF54637 1 136 2.86E-31 T 10-03-2017 IPR029069 HotDog domain RG49_RS08145 e9b407cd402ef39d77772a144291a64a 137 Pfam PF03061 Thioesterase superfamily 50 127 7.0E-17 T 10-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 RG49_RS12555 161cfa7537609e52d63ce338a0d0e2a3 110 SUPERFAMILY SSF54909 4 92 2.76E-14 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS12555 161cfa7537609e52d63ce338a0d0e2a3 110 Pfam PF07978 NIPSNAP 4 91 1.7E-6 T 10-03-2017 IPR012577 NIPSNAP RG49_RS06975 bd8d1bb35d5d6a080c118e83037cd587 240 SUPERFAMILY SSF52540 1 235 2.1E-80 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06975 bd8d1bb35d5d6a080c118e83037cd587 240 PIRSF PIRSF039085 1 240 2.5E-109 T 10-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 RG49_RS06975 bd8d1bb35d5d6a080c118e83037cd587 240 SMART SM00382 26 213 1.7E-16 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06975 bd8d1bb35d5d6a080c118e83037cd587 240 Pfam PF00005 ABC transporter 17 165 1.0E-36 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06975 bd8d1bb35d5d6a080c118e83037cd587 240 Gene3D G3DSA:3.40.50.300 1 237 4.7E-85 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06975 bd8d1bb35d5d6a080c118e83037cd587 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS22605 5ad11b8dd15ac87a21bcfaf34df828d2 179 ProDom PD095266 MEMBRANE YFGI EXPORTED 1 179 2.0E-80 T 10-03-2017 IPR020231 Uncharacterised protein family, YfgI RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 Gene3D G3DSA:3.40.50.720 7 185 1.0E-58 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 489 2.6E-205 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 188 488 4.9E-116 T 10-03-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 SUPERFAMILY SSF55347 176 488 4.25E-113 T 10-03-2017 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 489 90.731 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 SUPERFAMILY SSF51735 4 189 2.17E-55 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 176 182 - T 10-03-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 186 8.5E-57 T 10-03-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 218 235 8.6E-47 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 194 8.6E-47 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 142 155 8.6E-47 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 8.6E-47 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 236 252 8.6E-47 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 PIRSF PIRSF000110 1 491 2.8E-179 T 10-03-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 RG49_RS00670 9c7a231ae1bd88b4ab43e3a6bc1a93ee 491 Gene3D G3DSA:3.30.360.10 186 487 6.2E-122 T 10-03-2017 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 Pfam PF01202 Shikimate kinase 11 168 5.1E-48 T 10-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 SUPERFAMILY SSF52540 4 170 1.46E-27 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 Gene3D G3DSA:3.40.50.300 3 169 3.8E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 PRINTS PR01100 Shikimate kinase family signature 29 42 1.4E-25 T 10-03-2017 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 PRINTS PR01100 Shikimate kinase family signature 57 65 1.4E-25 T 10-03-2017 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 PRINTS PR01100 Shikimate kinase family signature 95 112 1.4E-25 T 10-03-2017 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 PRINTS PR01100 Shikimate kinase family signature 5 20 1.4E-25 T 10-03-2017 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 PRINTS PR01100 Shikimate kinase family signature 74 83 1.4E-25 T 10-03-2017 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 ProSitePatterns PS01128 Shikimate kinase signature. 58 82 - T 10-03-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 Hamap MF_01269 Shikimate kinase 2 [aroL]. 1 173 43.126 T 10-03-2017 IPR027544 Shikimate kinase 2 GO:0004765|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS09195 35629e2fbd76b27ac71366f4d32bce1b 174 Hamap MF_00109 Shikimate kinase [aroK]. 2 169 24.12 T 10-03-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 SUPERFAMILY SSF116726 390 450 1.57E-6 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 Pfam PF02254 TrkA-N domain 3 111 5.8E-30 T 10-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 Pfam PF02254 TrkA-N domain 235 350 3.2E-26 T 10-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.5E-36 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.5E-36 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.5E-36 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.5E-36 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.5E-36 T 10-03-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 SUPERFAMILY SSF51735 1 152 2.99E-36 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 SUPERFAMILY SSF51735 232 376 3.83E-33 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 Gene3D G3DSA:3.40.50.720 1 152 4.6E-50 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 Gene3D G3DSA:3.40.50.720 233 376 1.1E-37 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 SUPERFAMILY SSF116726 148 226 1.26E-8 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 Pfam PF02080 TrkA-C domain 390 451 1.3E-9 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS18155 14ae9bf094d37bed1c647b85d7a70d2d 458 Pfam PF02080 TrkA-C domain 157 225 1.6E-10 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS04485 53b7b48df20b76d574f0cdcce9c7eca8 236 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 8 161 1.2E-62 T 10-03-2017 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 RG49_RS04485 53b7b48df20b76d574f0cdcce9c7eca8 236 Gene3D G3DSA:1.10.3480.10 10 131 2.7E-7 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS04485 53b7b48df20b76d574f0cdcce9c7eca8 236 SUPERFAMILY SSF89155 5 163 3.92E-32 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS04485 53b7b48df20b76d574f0cdcce9c7eca8 236 Pfam PF02613 Nitrate reductase delta subunit 39 156 1.4E-12 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS20590 96ef7fedd00c49e5b3ce52fcd4e7511e 251 SUPERFAMILY SSF51261 41 242 8.37E-48 T 10-03-2017 IPR011055 Duplicated hybrid motif RG49_RS20590 96ef7fedd00c49e5b3ce52fcd4e7511e 251 Gene3D G3DSA:2.70.70.10 104 243 9.0E-40 T 10-03-2017 RG49_RS20590 96ef7fedd00c49e5b3ce52fcd4e7511e 251 Pfam PF01476 LysM domain 42 84 4.6E-14 T 10-03-2017 IPR018392 LysM domain RG49_RS20590 96ef7fedd00c49e5b3ce52fcd4e7511e 251 Pfam PF01551 Peptidase family M23 145 238 2.1E-31 T 10-03-2017 IPR016047 Peptidase M23 RG49_RS20590 96ef7fedd00c49e5b3ce52fcd4e7511e 251 Gene3D G3DSA:3.10.350.10 40 84 1.7E-17 T 10-03-2017 IPR018392 LysM domain RG49_RS20590 96ef7fedd00c49e5b3ce52fcd4e7511e 251 SMART SM00257 41 85 2.7E-16 T 10-03-2017 IPR018392 LysM domain RG49_RS09980 ccbaa0b5c12f805c73cdc23198d6be24 87 Gene3D G3DSA:1.10.10.60 9 48 4.1E-5 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09980 ccbaa0b5c12f805c73cdc23198d6be24 87 Pfam PF01527 Transposase 4 51 2.1E-8 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS09980 ccbaa0b5c12f805c73cdc23198d6be24 87 SUPERFAMILY SSF48295 1 50 1.57E-9 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS02025 b0b97b1fafbb337eb59c86e55531e4ce 111 ProDom PD028709 MEMBRANE INNER YDGC GLPM ALGINATE BIOSYNTHESIS TRANSMEMBRANE REQUIRED FOR UNCHARACTERIZED 23 111 3.0E-45 T 10-03-2017 IPR009707 Membrane protein GlpM/YdgC RG49_RS02025 b0b97b1fafbb337eb59c86e55531e4ce 111 Pfam PF06942 GlpM protein 5 111 5.2E-50 T 10-03-2017 IPR009707 Membrane protein GlpM/YdgC RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 SUPERFAMILY SSF53098 2 210 2.49E-67 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 SMART SM00341 210 289 1.2E-23 T 10-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 Pfam PF01612 3'-5' exonuclease 3 169 1.1E-47 T 10-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 Hamap MF_01899 Ribonuclease D [rnd]. 3 371 44.74 T 10-03-2017 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 Gene3D G3DSA:3.30.420.10 2 172 1.3E-14 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 SMART SM00474 3 171 6.7E-56 T 10-03-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 SUPERFAMILY SSF47819 295 372 3.58E-24 T 10-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 Pfam PF00570 HRDC domain 213 279 1.2E-14 T 10-03-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 TIGRFAM TIGR01388 rnd: ribonuclease D 5 372 2.0E-163 T 10-03-2017 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 RG49_RS00955 62d75e8942405c74c553862ea11b596d 375 SUPERFAMILY SSF47819 194 301 6.17E-29 T 10-03-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 SUPERFAMILY SSF159871 107 177 8.5E-17 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 SUPERFAMILY SSF159871 3 93 7.46E-22 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 PIRSF PIRSF014774 1 314 2.1E-185 T 10-03-2017 IPR025539 YdgH protein RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 Pfam PF07338 Protein of unknown function (DUF1471) 259 314 2.0E-20 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 Pfam PF07338 Protein of unknown function (DUF1471) 35 90 1.7E-17 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 Pfam PF07338 Protein of unknown function (DUF1471) 119 174 1.1E-17 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 Gene3D G3DSA:3.30.1660.10 249 314 8.0E-23 T 10-03-2017 IPR025543 Dodecin-like RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 Gene3D G3DSA:3.30.1660.10 25 90 2.3E-23 T 10-03-2017 IPR025543 Dodecin-like RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 Gene3D G3DSA:3.30.1660.10 109 175 1.1E-24 T 10-03-2017 IPR025543 Dodecin-like RG49_RS02045 3e495ad488f90b538c7e934663bb3f4c 314 SUPERFAMILY SSF159871 239 314 1.96E-18 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS17395 1a7429249c9ac80b169e1dfb5c75ff27 446 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 4 444 8.5E-180 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS17395 1a7429249c9ac80b169e1dfb5c75ff27 446 PIRSF PIRSF002746 1 446 4.0E-155 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS17395 1a7429249c9ac80b169e1dfb5c75ff27 446 Pfam PF02447 GntP family permease 5 441 1.4E-168 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS11890 edcdc223b82421100d4eca4cfcb1ed38 228 SUPERFAMILY SSF75217 2 157 1.31E-30 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS11890 edcdc223b82421100d4eca4cfcb1ed38 228 Pfam PF00588 SpoU rRNA Methylase family 3 153 3.4E-33 T 10-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 RG49_RS11890 edcdc223b82421100d4eca4cfcb1ed38 228 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 226 6.3E-83 T 10-03-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 RG49_RS11890 edcdc223b82421100d4eca4cfcb1ed38 228 Gene3D G3DSA:3.40.1280.10 2 159 6.5E-28 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS11890 edcdc223b82421100d4eca4cfcb1ed38 228 PIRSF PIRSF004808 1 228 4.0E-65 T 10-03-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 RG49_RS06390 4b7a3f51272ca18bde25fb5620f014f3 299 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 135 296 1.0E-73 T 10-03-2017 IPR005642 Lysine exporter LysO RG49_RS06390 4b7a3f51272ca18bde25fb5620f014f3 299 Pfam PF03956 Membrane protein of unknown function (DUF340) 113 297 5.9E-58 T 10-03-2017 IPR005642 Lysine exporter LysO RG49_RS20350 c676d7a5e37881537273eca495577ba4 109 SUPERFAMILY SSF102829 6 94 1.01E-25 T 10-03-2017 IPR007838 Cell division protein ZapA-like RG49_RS20350 c676d7a5e37881537273eca495577ba4 109 Pfam PF05164 Cell division protein ZapA 6 90 4.2E-20 T 10-03-2017 IPR007838 Cell division protein ZapA-like RG49_RS20350 c676d7a5e37881537273eca495577ba4 109 Hamap MF_02012 Cell division protein ZapA [zapA]. 1 109 36.753 T 10-03-2017 IPR023771 Cell division protein ZapA, eubacteria RG49_RS17585 ffd3ae488feb0a7b0ad90f4f5fa81c8d 133 SMART SM00363 9 72 1.2E-11 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS17585 ffd3ae488feb0a7b0ad90f4f5fa81c8d 133 PIRSF PIRSF016821 6 133 5.3E-41 T 10-03-2017 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 RG49_RS17585 ffd3ae488feb0a7b0ad90f4f5fa81c8d 133 SUPERFAMILY SSF55174 7 103 4.32E-31 T 10-03-2017 RG49_RS17585 ffd3ae488feb0a7b0ad90f4f5fa81c8d 133 Pfam PF01479 S4 domain 9 53 2.8E-13 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS17585 ffd3ae488feb0a7b0ad90f4f5fa81c8d 133 Gene3D G3DSA:3.10.290.10 7 103 4.0E-39 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS13245 9de8c859930b5dd0da696c9e2c30583b 112 Hamap MF_01160 Divalent-cation tolerance protein CutA [cutA]. 1 112 42.162 T 10-03-2017 IPR023700 Divalent cation tolerance protein CutA, bacteria GO:0005507|GO:0005737 RG49_RS13245 9de8c859930b5dd0da696c9e2c30583b 112 Gene3D G3DSA:3.30.70.830 3 111 1.5E-40 T 10-03-2017 RG49_RS13245 9de8c859930b5dd0da696c9e2c30583b 112 SUPERFAMILY SSF54913 11 111 4.08E-35 T 10-03-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta RG49_RS13245 9de8c859930b5dd0da696c9e2c30583b 112 Pfam PF03091 CutA1 divalent ion tolerance protein 12 109 5.1E-34 T 10-03-2017 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 RG49_RS24740 aadf0bfaad61658cb9864e989c62ddae 425 Pfam PF07690 Major Facilitator Superfamily 24 313 1.1E-19 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS24740 aadf0bfaad61658cb9864e989c62ddae 425 TIGRFAM TIGR00897 2A0118: polyol permease 2 406 1.2E-189 T 10-03-2017 IPR004748 Polyol permease GO:0005215|GO:0006810|GO:0016021 RG49_RS24740 aadf0bfaad61658cb9864e989c62ddae 425 Gene3D G3DSA:1.20.1250.20 224 410 7.8E-22 T 10-03-2017 RG49_RS24740 aadf0bfaad61658cb9864e989c62ddae 425 Gene3D G3DSA:1.20.1250.20 15 196 1.4E-14 T 10-03-2017 RG49_RS24740 aadf0bfaad61658cb9864e989c62ddae 425 SUPERFAMILY SSF103473 12 412 4.97E-44 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS18385 2d10212c414dea72e3a8a92fa95b0c70 489 Pfam PF10150 Ribonuclease E/G family 124 393 7.9E-102 T 10-03-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 RG49_RS18385 2d10212c414dea72e3a8a92fa95b0c70 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 426 9.9E-179 T 10-03-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 RG49_RS18385 2d10212c414dea72e3a8a92fa95b0c70 489 Pfam PF00575 S1 RNA binding domain 38 109 1.4E-6 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS18385 2d10212c414dea72e3a8a92fa95b0c70 489 SMART SM00316 37 122 1.2E-9 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS18385 2d10212c414dea72e3a8a92fa95b0c70 489 Gene3D G3DSA:2.40.50.140 30 128 1.1E-33 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS18385 2d10212c414dea72e3a8a92fa95b0c70 489 SUPERFAMILY SSF50249 39 128 2.62E-19 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 SUPERFAMILY SSF51735 10 249 3.31E-83 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.5E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 3.5E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 3.5E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.9E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 6.9E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 6.9E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 6.9E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 6.9E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 6.9E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 Gene3D G3DSA:3.40.50.720 6 249 3.6E-86 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01965 b9f5d8464c860a1b8eaf9ba5d8442b1a 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 8.9E-66 T 10-03-2017 RG49_RS20240 51e2fa066fc9a29add8a19230669a6b2 169 SUPERFAMILY SSF158668 2 167 4.71E-54 T 10-03-2017 RG49_RS20240 51e2fa066fc9a29add8a19230669a6b2 169 Gene3D G3DSA:1.20.120.330 2 168 2.6E-63 T 10-03-2017 RG49_RS20240 51e2fa066fc9a29add8a19230669a6b2 169 Pfam PF05068 Mannitol repressor 5 167 3.1E-52 T 10-03-2017 IPR007761 Mannitol repressor RG49_RS03185 a5910205e128da53ccbd48dd02f8a97b 474 Gene3D G3DSA:3.40.309.10 259 437 3.1E-61 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS03185 a5910205e128da53ccbd48dd02f8a97b 474 TIGRFAM TIGR03374 ABALDH: 1-pyrroline dehydrogenase 2 473 0.0 T 10-03-2017 IPR017749 1-pyrroline dehydrogenase GO:0009447|GO:0019145|GO:0051287|GO:0055114 KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3 RG49_RS03185 a5910205e128da53ccbd48dd02f8a97b 474 Hamap MF_01275 Gamma-aminobutyraldehyde dehydrogenase [prr]. 1 474 89.417 T 10-03-2017 IPR017749 1-pyrroline dehydrogenase GO:0009447|GO:0019145|GO:0051287|GO:0055114 KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3 RG49_RS03185 a5910205e128da53ccbd48dd02f8a97b 474 SUPERFAMILY SSF53720 2 473 1.44E-157 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS03185 a5910205e128da53ccbd48dd02f8a97b 474 Gene3D G3DSA:3.40.605.10 2 258 1.6E-96 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03185 a5910205e128da53ccbd48dd02f8a97b 474 Pfam PF00171 Aldehyde dehydrogenase family 13 470 2.6E-166 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03185 a5910205e128da53ccbd48dd02f8a97b 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS13345 06bd095844d1521af83312ef0cd60b98 209 PIRSF PIRSF020606 1 204 5.7E-84 T 10-03-2017 IPR014509 Uncharacterised conserved protein UCP020606 RG49_RS13345 06bd095844d1521af83312ef0cd60b98 209 Pfam PF09997 Predicted membrane protein (DUF2238) 42 182 3.8E-56 T 10-03-2017 IPR014509 Uncharacterised conserved protein UCP020606 RG49_RS20235 b3e81f00d7d1e583ef27fcbc0816d6a1 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 4 321 2.6E-121 T 10-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 RG49_RS20235 b3e81f00d7d1e583ef27fcbc0816d6a1 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 321 1.4E-177 T 10-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 RG49_RS20235 b3e81f00d7d1e583ef27fcbc0816d6a1 321 SUPERFAMILY SSF56655 2 321 2.26E-99 T 10-03-2017 RG49_RS20235 b3e81f00d7d1e583ef27fcbc0816d6a1 321 Gene3D G3DSA:3.30.540.10 171 321 1.7E-36 T 10-03-2017 RG49_RS20235 b3e81f00d7d1e583ef27fcbc0816d6a1 321 Gene3D G3DSA:3.30.540.10 4 170 4.1E-61 T 10-03-2017 RG49_RS20235 b3e81f00d7d1e583ef27fcbc0816d6a1 321 PIRSF PIRSF004532 1 321 4.1E-135 T 10-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 RG49_RS19140 24875adb4d2550b6da24948f620f7f72 764 Gene3D G3DSA:3.20.70.20 9 762 0.0 T 10-03-2017 RG49_RS19140 24875adb4d2550b6da24948f620f7f72 764 PIRSF PIRSF000379 12 764 0.0 T 10-03-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 RG49_RS19140 24875adb4d2550b6da24948f620f7f72 764 Pfam PF01228 Glycine radical 634 745 4.6E-42 T 10-03-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 RG49_RS19140 24875adb4d2550b6da24948f620f7f72 764 SUPERFAMILY SSF51998 8 762 1.97E-285 T 10-03-2017 RG49_RS19140 24875adb4d2550b6da24948f620f7f72 764 ProSitePatterns PS00850 Glycine radical domain signature. 734 742 - T 10-03-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site RG49_RS19140 24875adb4d2550b6da24948f620f7f72 764 Pfam PF02901 Pyruvate formate lyase-like 27 618 1.6E-194 T 10-03-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 RG49_RS19140 24875adb4d2550b6da24948f620f7f72 764 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 15 764 0.0 T 10-03-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 RG49_RS14485 e81e68988795aeb2ce9835959f9626ea 79 Hamap MF_01196 Cell division protein ZapB [zapB]. 1 79 18.505 T 10-03-2017 IPR009252 Cell division protein ZapB GO:0000917|GO:0005737|GO:0043093 RG49_RS14485 e81e68988795aeb2ce9835959f9626ea 79 Pfam PF06005 Protein of unknown function (DUF904) 1 78 2.6E-25 T 10-03-2017 IPR009252 Cell division protein ZapB GO:0000917|GO:0005737|GO:0043093 RG49_RS15760 b1699e64fb45a8a9bf64c0c28e9319f2 205 SUPERFAMILY SSF51569 2 204 3.48E-59 T 10-03-2017 RG49_RS15760 b1699e64fb45a8a9bf64c0c28e9319f2 205 Gene3D G3DSA:3.20.20.70 2 202 4.0E-70 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS15760 b1699e64fb45a8a9bf64c0c28e9319f2 205 Pfam PF01081 KDPG and KHG aldolase 5 183 1.7E-29 T 10-03-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 Hamap MF_00504 Peptidase B [pepB]. 3 427 64.362 T 10-03-2017 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 PIRSF PIRSF036388 1 427 2.2E-238 T 10-03-2017 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 Pfam PF12404 Peptidase 5 81 6.5E-34 T 10-03-2017 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 PRINTS PR00481 Cytosol aminopeptidase signature 190 207 3.3E-46 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 PRINTS PR00481 Cytosol aminopeptidase signature 249 270 3.3E-46 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 PRINTS PR00481 Cytosol aminopeptidase signature 212 233 3.3E-46 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 PRINTS PR00481 Cytosol aminopeptidase signature 271 291 3.3E-46 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 PRINTS PR00481 Cytosol aminopeptidase signature 299 314 3.3E-46 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 275 282 - T 10-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 SUPERFAMILY SSF53187 108 426 5.02E-103 T 10-03-2017 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 109 421 1.7E-100 T 10-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 RG49_RS22455 6ee152a5a913b9821bafe71b6237e54c 427 Gene3D G3DSA:3.40.630.10 98 426 4.9E-117 T 10-03-2017 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.319 T 10-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 Gene3D G3DSA:4.10.910.10 72 118 8.3E-28 T 10-03-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 SUPERFAMILY SSF46946 2 114 4.71E-45 T 10-03-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.8E-52 T 10-03-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 PIRSF PIRSF002134 1 118 5.0E-41 T 10-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 Gene3D G3DSA:1.10.8.50 2 71 8.9E-27 T 10-03-2017 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 10-03-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18110 664a2e56c1e17b694a7b948bb241b549 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 7.2E-34 T 10-03-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17885 b9e7f5387777af7bb242027636c4dd41 119 SUPERFAMILY SSF75169 1 119 2.22E-35 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS17885 b9e7f5387777af7bb242027636c4dd41 119 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 3 119 4.9E-46 T 10-03-2017 IPR017462 Sulphur relay, TusC/DsrF RG49_RS17885 b9e7f5387777af7bb242027636c4dd41 119 Pfam PF02635 DsrE/DsrF-like family 2 119 3.5E-24 T 10-03-2017 IPR003787 Sulphur relay, DsrE/F-like protein RG49_RS17885 b9e7f5387777af7bb242027636c4dd41 119 Gene3D G3DSA:3.40.1260.10 1 119 1.7E-48 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS17885 b9e7f5387777af7bb242027636c4dd41 119 Hamap MF_00389 Protein TusC [tusC]. 1 119 35.777 T 10-03-2017 IPR017462 Sulphur relay, TusC/DsrF RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 SUPERFAMILY SSF52096 5 318 3.45E-103 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 5.9E-50 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 5.9E-50 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 5.9E-50 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 5.9E-50 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 5.9E-50 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 5.9E-50 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 50.552 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 Gene3D G3DSA:3.90.226.10 59 278 4.9E-49 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 1.8E-173 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS10890 ecad122ea2e955a8f798d20bffccbf20 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 151 2.4E-62 T 10-03-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 SUPERFAMILY SSF49354 31 148 6.02E-35 T 10-03-2017 IPR008962 PapD-like RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 104 121 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 Gene3D G3DSA:2.60.40.1070 154 229 8.3E-27 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 31 148 7.8E-35 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 SUPERFAMILY SSF49584 142 227 4.45E-22 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 Gene3D G3DSA:2.60.40.360 31 149 1.9E-38 T 10-03-2017 IPR008962 PapD-like RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 PRINTS PR00969 Pili chaperone signature 32 41 2.8E-28 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 PRINTS PR00969 Pili chaperone signature 77 98 2.8E-28 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 PRINTS PR00969 Pili chaperone signature 130 145 2.8E-28 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 PRINTS PR00969 Pili chaperone signature 105 122 2.8E-28 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 PRINTS PR00969 Pili chaperone signature 165 180 2.8E-28 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS06025 73ccc6a4209edad5a10c44b92e065f92 233 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 170 226 3.1E-16 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 SUPERFAMILY SSF48498 87 212 6.47E-42 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 Gene3D G3DSA:1.10.357.10 79 212 1.8E-59 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 Pfam PF08362 YcdC-like protein, C-terminal region 70 212 5.7E-59 T 10-03-2017 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 SUPERFAMILY SSF46689 13 90 1.25E-19 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 Gene3D G3DSA:1.10.10.60 10 52 2.0E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.6E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.6E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 TIGRFAM TIGR03613 RutR: pyrimidine utilization regulatory protein R 11 212 1.5E-116 T 10-03-2017 IPR019915 Transcription regulator, pyrimidine utilisation, RutR RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 Gene3D G3DSA:1.10.10.60 53 78 7.4E-8 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS05630 eb9b9a05110a11a2cf9ed5fbe3e01cdb 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 6.2E-15 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 SUPERFAMILY SSF52283 2 135 1.89E-45 T 10-03-2017 RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 SUPERFAMILY SSF51735 102 298 1.12E-55 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 Gene3D G3DSA:3.40.50.720 1 137 2.0E-51 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 327 5.1E-35 T 10-03-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 10-03-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 10-03-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 Gene3D G3DSA:3.40.50.720 138 305 8.5E-45 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03495 035d31818ee331523ed89644e47d97dc 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 297 4.1E-53 T 10-03-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 RG49_RS10900 d7a3a5e13c1c51387522d19a7825cf8f 198 Hamap MF_00052_B Ribonuclease HII [rnhB]. 11 190 39.634 T 10-03-2017 IPR022898 Ribonuclease HII GO:0004523 RG49_RS10900 d7a3a5e13c1c51387522d19a7825cf8f 198 Gene3D G3DSA:3.30.420.10 11 151 6.4E-49 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10900 d7a3a5e13c1c51387522d19a7825cf8f 198 SUPERFAMILY SSF53098 3 195 1.82E-70 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10900 d7a3a5e13c1c51387522d19a7825cf8f 198 Pfam PF01351 Ribonuclease HII 13 188 6.5E-39 T 10-03-2017 IPR024567 Ribonuclease HII/HIII domain RG49_RS24915 899e85fc0cdbc4f29f0831c31461e63d 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 125 157 5.5E-7 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS24915 899e85fc0cdbc4f29f0831c31461e63d 182 SUPERFAMILY SSF51161 21 177 1.52E-38 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS24915 899e85fc0cdbc4f29f0831c31461e63d 182 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 133 161 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS24915 899e85fc0cdbc4f29f0831c31461e63d 182 Gene3D G3DSA:2.160.10.10 21 180 7.6E-42 T 10-03-2017 RG49_RS24915 899e85fc0cdbc4f29f0831c31461e63d 182 TIGRFAM TIGR04008 WcaF: colanic acid biosynthesis acetyltransferase WcaF 1 180 3.6E-121 T 10-03-2017 IPR024005 Colanic acid biosynthesis, acetyltransferase, WcaF RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 10-03-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 Pfam PF00709 Adenylosuccinate synthetase 5 423 1.0E-176 T 10-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 Gene3D G3DSA:3.90.170.10 268 426 9.0E-66 T 10-03-2017 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 SMART SM00788 4 425 6.7E-302 T 10-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 SUPERFAMILY SSF52540 3 431 1.49E-180 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 10-03-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 Gene3D G3DSA:3.40.440.10 4 94 1.3E-71 T 10-03-2017 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 Gene3D G3DSA:3.40.440.10 196 266 1.3E-71 T 10-03-2017 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 Gene3D G3DSA:1.10.300.10 103 195 1.6E-38 T 10-03-2017 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 218.673 T 10-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 RG49_RS13030 c75382fff9ecc0ede3bf989eaa3734cf 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 430 2.2E-210 T 10-03-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 Gene3D G3DSA:3.90.850.10 219 427 1.1E-76 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 SUPERFAMILY SSF56529 218 426 1.01E-70 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 3 203 1.9E-90 T 10-03-2017 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 SUPERFAMILY SSF56529 2 210 5.23E-54 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 Gene3D G3DSA:3.90.850.10 3 208 5.3E-53 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 219 425 2.4E-104 T 10-03-2017 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 226 422 1.3E-57 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS12190 dfcf3870f72b33f7a5fe5fa9060f2ff6 429 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 5 204 1.8E-39 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 Pfam PF00375 Sodium:dicarboxylate symporter family 8 411 4.4E-116 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 SUPERFAMILY SSF118215 8 412 3.53E-121 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 6 26 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 365 385 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 155 177 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 3.5E-52 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS13610 c04f0843393a4843e45a949d28239222 437 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 306 329 - T 10-03-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site RG49_RS13610 c04f0843393a4843e45a949d28239222 437 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 43 58 - T 10-03-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site RG49_RS13610 c04f0843393a4843e45a949d28239222 437 Gene3D G3DSA:1.10.3860.10 3 416 2.6E-128 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS09350 bcbd4cdb0268ca8a2c022422865ad231 179 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 5 179 3.6E-60 T 10-03-2017 IPR018636 Protein of unknown function DUF2058 RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 SMART SM00345 18 77 4.8E-20 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.4E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.4E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 Gene3D G3DSA:1.20.120.530 104 226 2.3E-17 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 SUPERFAMILY SSF48008 106 226 3.14E-19 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 SUPERFAMILY SSF46785 10 81 7.61E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 Gene3D G3DSA:1.10.10.10 11 87 6.9E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 Pfam PF07729 FCD domain 108 226 1.9E-19 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 5.2E-19 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15435 a5ae3776a8b5c14e52624dd28e568860 230 SMART SM00895 106 227 2.9E-17 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS10310 48f30b3a03fa65bb6df9a5639d211014 577 Pfam PF03354 Phage Terminase 86 558 1.1E-67 T 10-03-2017 IPR005021 Phage terminase RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 Gene3D G3DSA:3.40.50.1000 177 265 2.1E-56 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 Gene3D G3DSA:3.40.50.1000 1 72 2.1E-56 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 231 7.3E-27 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 Gene3D G3DSA:3.30.1240.10 82 176 1.6E-17 T 10-03-2017 RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 260 1.5E-70 T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 SUPERFAMILY SSF56784 1 264 1.52E-68 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 260 1.9E-62 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15060 cfd47bf4d83dd1e7f47a19090b82f4dc 266 ProSitePatterns PS01229 Hypothetical cof family signature 2. 212 234 - T 10-03-2017 RG49_RS00875 4c553198e7900ab1cdf0390884503954 266 Pfam PF03609 PTS system sorbose-specific iic component 6 237 3.8E-76 T 10-03-2017 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 RG49_RS00875 4c553198e7900ab1cdf0390884503954 266 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 1 266 1.9E-132 T 10-03-2017 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 RG49_RS15705 416a808f4fc13ba68768cf7d39153fcd 46 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.6E-27 T 10-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS15705 416a808f4fc13ba68768cf7d39153fcd 46 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.163 T 10-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS15705 416a808f4fc13ba68768cf7d39153fcd 46 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 31 4.0E-11 T 10-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS15705 416a808f4fc13ba68768cf7d39153fcd 46 Pfam PF00468 Ribosomal protein L34 1 44 1.7E-24 T 10-03-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS15705 416a808f4fc13ba68768cf7d39153fcd 46 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 10-03-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14440 0af7e31a18234f965060b62674d30a37 202 SUPERFAMILY SSF54001 19 195 1.06E-50 T 10-03-2017 RG49_RS14440 0af7e31a18234f965060b62674d30a37 202 Gene3D G3DSA:2.30.30.330 19 197 4.3E-62 T 10-03-2017 RG49_RS14440 0af7e31a18234f965060b62674d30a37 202 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 21 193 1.4E-52 T 10-03-2017 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 SUPERFAMILY SSF102114 127 373 4.19E-64 T 10-03-2017 RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 10-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 6.3E-223 T 10-03-2017 RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 7.7E-160 T 10-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 Gene3D G3DSA:3.80.30.20 146 380 8.7E-80 T 10-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 Pfam PF04055 Radical SAM superfamily 151 325 2.2E-27 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 75.56 T 10-03-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 SMART SM00729 147 367 7.6E-65 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 Pfam PF01938 TRAM domain 378 440 6.2E-21 T 10-03-2017 IPR002792 TRAM domain RG49_RS07800 f35ceae8be8a2b1d298ba3a79f389400 474 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 3.0E-29 T 10-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 259 3.8E-42 T 10-03-2017 RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.9E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.9E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.9E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.9E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.9E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 SUPERFAMILY SSF51735 7 260 1.47E-54 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12860 fabcba65eb1389245e36bb2268d90f53 263 Gene3D G3DSA:3.40.50.720 5 260 4.6E-56 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03600 3dfb845042e9908b27e50d9414dde2ac 263 SMART SM00470 8 94 2.9E-19 T 10-03-2017 IPR003115 ParB/Sulfiredoxin RG49_RS03600 3dfb845042e9908b27e50d9414dde2ac 263 Pfam PF02195 ParB-like nuclease domain 11 93 6.5E-15 T 10-03-2017 IPR003115 ParB/Sulfiredoxin RG49_RS03600 3dfb845042e9908b27e50d9414dde2ac 263 SUPERFAMILY SSF110849 7 143 5.93E-30 T 10-03-2017 IPR003115 ParB/Sulfiredoxin RG49_RS03600 3dfb845042e9908b27e50d9414dde2ac 263 Gene3D G3DSA:3.90.1530.10 4 94 7.0E-19 T 10-03-2017 RG49_RS18290 02f1c157bd6aa4baecff1c5a7693e6d9 59 ProDom PD052549 YHDU TRANSMEMBRANE MEMBRANE PERIPLASMIC 1 53 8.0E-14 T 10-03-2017 IPR022540 Protein of unknown function DUF2556 RG49_RS18290 02f1c157bd6aa4baecff1c5a7693e6d9 59 Pfam PF10831 Protein of unknown function (DUF2556) 1 53 4.2E-35 T 10-03-2017 IPR022540 Protein of unknown function DUF2556 RG49_RS19985 43655ec5724852615de58cf7500fb890 261 ProSitePatterns PS01141 Bacterial type II secretion system protein C signature. 198 224 - T 10-03-2017 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 RG49_RS19985 43655ec5724852615de58cf7500fb890 261 Gene3D G3DSA:2.30.42.10 189 258 1.4E-8 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS19985 43655ec5724852615de58cf7500fb890 261 TIGRFAM TIGR01713 typeII_sec_gspC: type II secretion system protein C 39 259 5.2E-41 T 10-03-2017 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 RG49_RS19985 43655ec5724852615de58cf7500fb890 261 Pfam PF11356 Type II secretion system protein C 1 127 1.5E-27 T 10-03-2017 IPR024961 Type II secretion system protein C, N-terminal RG49_RS19985 43655ec5724852615de58cf7500fb890 261 SUPERFAMILY SSF50156 165 259 4.21E-15 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.3E-21 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 Pfam PF13377 Periplasmic binding protein-like domain 172 331 2.3E-34 T 10-03-2017 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 10-03-2017 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 Gene3D G3DSA:1.10.260.40 3 58 1.2E-25 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 SUPERFAMILY SSF53822 61 333 1.83E-68 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 Gene3D G3DSA:3.40.50.2300 59 169 9.6E-35 T 10-03-2017 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 SUPERFAMILY SSF47413 2 60 3.1E-19 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 Gene3D G3DSA:3.40.50.2300 170 331 6.6E-50 T 10-03-2017 RG49_RS21510 52f881bf24d3273e92ba8e9f5c6c9e2c 337 SMART SM00354 2 72 9.1E-36 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 SUPERFAMILY SSF51338 3 77 2.54E-18 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 9 388 6.6E-188 T 10-03-2017 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 Gene3D G3DSA:2.30.40.10 10 70 5.0E-15 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 Gene3D G3DSA:3.20.20.140 71 342 3.1E-126 T 10-03-2017 RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 SUPERFAMILY SSF51556 63 346 4.08E-72 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 SUPERFAMILY SSF51338 346 388 8.64E-8 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 PIRSF PIRSF001238 8 389 1.9E-158 T 10-03-2017 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 RG49_RS12360 ade577cc5c523b8d26ea2159d6f19d62 390 Pfam PF01979 Amidohydrolase family 264 374 6.1E-6 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.4E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.4E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.4E-8 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.1E-34 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.1E-34 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.1E-34 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.1E-34 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.1E-34 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.1E-34 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 Gene3D G3DSA:3.40.50.720 2 249 3.9E-77 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 SUPERFAMILY SSF51735 6 249 1.91E-74 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS25260 8c4dc641de15d4a5a044ae9528ed3540 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 247 5.2E-59 T 10-03-2017 RG49_RS01565 e657646640ceff45fda85e4e664a4552 288 Gene3D G3DSA:3.40.50.720 112 284 7.8E-46 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01565 e657646640ceff45fda85e4e664a4552 288 Gene3D G3DSA:3.40.192.10 3 111 6.1E-37 T 10-03-2017 RG49_RS01565 e657646640ceff45fda85e4e664a4552 288 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 1.0E-26 T 10-03-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 RG49_RS01565 e657646640ceff45fda85e4e664a4552 288 SUPERFAMILY SSF51735 107 283 2.96E-38 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01565 e657646640ceff45fda85e4e664a4552 288 Hamap MF_01578 Quinate/shikimate dehydrogenase [ydiB]. 1 288 82.224 T 10-03-2017 IPR022872 Quinate/Shikimate dehydrogenase GO:0004764|GO:0030266|GO:0052733|GO:0052734|GO:0055114 KEGG: 00400+1.1.1.282|KEGG: 00620+1.1.1.28|MetaCyc: PWY-6163|MetaCyc: PWY-6454|MetaCyc: PWY-6901 RG49_RS01565 e657646640ceff45fda85e4e664a4552 288 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 286 30.366 T 10-03-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 RG49_RS01565 e657646640ceff45fda85e4e664a4552 288 SUPERFAMILY SSF53223 4 106 5.64E-30 T 10-03-2017 RG49_RS24925 05245b664769289d1c34e95928181f46 321 Gene3D G3DSA:3.90.25.10 300 318 5.1E-13 T 10-03-2017 RG49_RS24925 05245b664769289d1c34e95928181f46 321 Gene3D G3DSA:3.90.25.10 205 219 5.1E-13 T 10-03-2017 RG49_RS24925 05245b664769289d1c34e95928181f46 321 Gene3D G3DSA:3.90.25.10 259 299 1.6E-39 T 10-03-2017 RG49_RS24925 05245b664769289d1c34e95928181f46 321 Gene3D G3DSA:3.90.25.10 169 204 1.6E-39 T 10-03-2017 RG49_RS24925 05245b664769289d1c34e95928181f46 321 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 3 314 49.547 T 10-03-2017 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 RG49_RS24925 05245b664769289d1c34e95928181f46 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 228 3.7E-73 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS24925 05245b664769289d1c34e95928181f46 321 SUPERFAMILY SSF51735 1 318 1.66E-73 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24925 05245b664769289d1c34e95928181f46 321 Gene3D G3DSA:3.40.50.720 1 168 2.3E-45 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24925 05245b664769289d1c34e95928181f46 321 Gene3D G3DSA:3.40.50.720 220 258 2.3E-45 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 Pfam PF02872 5'-nucleotidase, C-terminal domain 363 509 2.7E-32 T 10-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 Pfam PF00149 Calcineurin-like phosphoesterase 35 254 4.7E-18 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 SUPERFAMILY SSF55816 363 543 5.76E-54 T 10-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 Gene3D G3DSA:3.90.780.10 363 540 1.3E-56 T 10-03-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 Gene3D G3DSA:3.60.21.10 28 361 4.9E-96 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 ProSitePatterns PS00785 5'-nucleotidase signature 1. 34 46 - T 10-03-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 SUPERFAMILY SSF56300 27 360 1.78E-94 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 PRINTS PR01607 Apyrase family signature 207 224 2.1E-62 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 PRINTS PR01607 Apyrase family signature 32 50 2.1E-62 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 PRINTS PR01607 Apyrase family signature 283 303 2.1E-62 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 PRINTS PR01607 Apyrase family signature 238 261 2.1E-62 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 PRINTS PR01607 Apyrase family signature 417 440 2.1E-62 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 PRINTS PR01607 Apyrase family signature 484 503 2.1E-62 T 10-03-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS08690 acd6e2367d87dbff7971d0b93bd179e7 550 ProSitePatterns PS00786 5'-nucleotidase signature 2. 109 120 - T 10-03-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 RG49_RS24305 2ad05bb17916db3f6339fc6ea51c3fff 393 Pfam PF07690 Major Facilitator Superfamily 21 356 7.1E-37 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS24305 2ad05bb17916db3f6339fc6ea51c3fff 393 SUPERFAMILY SSF103473 19 390 1.05E-50 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS24305 2ad05bb17916db3f6339fc6ea51c3fff 393 TIGRFAM TIGR00899 2A0120: sugar efflux transporter 19 392 9.0E-198 T 10-03-2017 IPR004750 Sugar efflux GO:0008643|GO:0015542|GO:0016021 RG49_RS24305 2ad05bb17916db3f6339fc6ea51c3fff 393 Gene3D G3DSA:1.20.1250.20 19 199 6.6E-19 T 10-03-2017 RG49_RS24305 2ad05bb17916db3f6339fc6ea51c3fff 393 Gene3D G3DSA:1.20.1250.20 213 391 1.8E-24 T 10-03-2017 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 Pfam PF00239 Resolvase, N terminal domain 3 135 1.1E-49 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 Gene3D G3DSA:3.40.50.1390 1 119 2.2E-45 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 SUPERFAMILY SSF53041 1 136 5.49E-48 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 Gene3D G3DSA:1.10.10.60 138 183 5.9E-24 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 SUPERFAMILY SSF46689 138 180 2.51E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 Pfam PF02796 Helix-turn-helix domain of resolvase 138 180 1.1E-11 T 10-03-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 RG49_RS10175 ba3571c04dbcdf25e7bd86ab2e5d3590 184 SMART SM00857 2 136 3.4E-64 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS25220 df25bb36bb5f55127030aca9ede28bd2 94 SUPERFAMILY SSF52794 1 92 1.02E-16 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS25220 df25bb36bb5f55127030aca9ede28bd2 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 61 9.8E-11 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS25220 df25bb36bb5f55127030aca9ede28bd2 94 Gene3D G3DSA:3.40.50.270 1 92 2.7E-24 T 10-03-2017 RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 Gene3D G3DSA:3.40.50.300 254 453 1.9E-55 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 SMART SM00487 265 459 2.0E-31 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 SUPERFAMILY SSF52540 206 453 4.6E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 Gene3D G3DSA:3.40.50.300 454 638 4.8E-42 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 SUPERFAMILY SSF52540 508 653 1.27E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 SUPERFAMILY SSF52540 292 342 1.27E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 Gene3D G3DSA:2.40.50.140 47 138 4.1E-30 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 29 664 4.0E-253 T 10-03-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 Gene3D G3DSA:1.10.150.20 5 37 2.7E-4 T 10-03-2017 RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 SMART SM00490 505 589 4.4E-22 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 Pfam PF00271 Helicase conserved C-terminal domain 481 588 1.8E-18 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 Pfam PF17191 RecG wedge domain 14 171 9.6E-21 T 10-03-2017 IPR033454 RecG, wedge domain RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 SUPERFAMILY SSF50249 9 176 3.26E-42 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16135 011bb79012a0068ffc132a68870f32da 693 Pfam PF00270 DEAD/DEAH box helicase 273 433 7.8E-19 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS08245 6f115f83682d28c28310227aa33a57c8 69 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 30 49 - T 10-03-2017 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 RG49_RS08245 6f115f83682d28c28310227aa33a57c8 69 PRINTS PR00281 Hok/Gef cell toxic protein family signature 45 67 1.2E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS08245 6f115f83682d28c28310227aa33a57c8 69 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 43 1.2E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS08245 6f115f83682d28c28310227aa33a57c8 69 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 24 68 1.0E-5 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS08245 6f115f83682d28c28310227aa33a57c8 69 Pfam PF01848 Hok/gef family 25 66 1.0E-20 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS11800 6f115f83682d28c28310227aa33a57c8 69 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 30 49 - T 10-03-2017 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 RG49_RS11800 6f115f83682d28c28310227aa33a57c8 69 PRINTS PR00281 Hok/Gef cell toxic protein family signature 45 67 1.2E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS11800 6f115f83682d28c28310227aa33a57c8 69 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 43 1.2E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS11800 6f115f83682d28c28310227aa33a57c8 69 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 24 68 1.0E-5 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS11800 6f115f83682d28c28310227aa33a57c8 69 Pfam PF01848 Hok/gef family 25 66 1.0E-20 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS23525 ff72e6c4d0b3faf9e08816a9063573e7 189 Gene3D G3DSA:3.40.50.1950 2 188 1.1E-77 T 10-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 RG49_RS23525 ff72e6c4d0b3faf9e08816a9063573e7 189 Pfam PF02441 Flavoprotein 2 127 1.6E-26 T 10-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 RG49_RS23525 ff72e6c4d0b3faf9e08816a9063573e7 189 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 188 37.073 T 10-03-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 RG49_RS23525 ff72e6c4d0b3faf9e08816a9063573e7 189 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 186 2.0E-70 T 10-03-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 RG49_RS23525 ff72e6c4d0b3faf9e08816a9063573e7 189 SUPERFAMILY SSF52507 2 186 1.83E-59 T 10-03-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 RG49_RS06055 db0e6bc8c6fbb2d443fc241427af538d 263 Gene3D G3DSA:1.10.3720.10 55 249 3.4E-27 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06055 db0e6bc8c6fbb2d443fc241427af538d 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 247 8.3E-28 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06055 db0e6bc8c6fbb2d443fc241427af538d 263 SUPERFAMILY SSF161098 56 237 4.97E-36 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 Pfam PF03023 MviN-like protein 28 478 1.0E-162 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PIRSF PIRSF002869 1 511 6.9E-184 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 508 1.3E-180 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PRINTS PR01806 Virulence factor MviN signature 33 52 2.2E-87 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PRINTS PR01806 Virulence factor MviN signature 52 68 2.2E-87 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PRINTS PR01806 Virulence factor MviN signature 157 178 2.2E-87 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PRINTS PR01806 Virulence factor MviN signature 259 285 2.2E-87 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PRINTS PR01806 Virulence factor MviN signature 409 426 2.2E-87 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PRINTS PR01806 Virulence factor MviN signature 357 376 2.2E-87 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS05300 30a2e7ab99ac77723ce65658e8e06c01 511 PRINTS PR01806 Virulence factor MviN signature 133 157 2.2E-87 T 10-03-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ RG49_RS00370 bf94dd6b0d29d5a0baed2911e06ec564 221 SUPERFAMILY SSF101327 14 182 2.88E-23 T 10-03-2017 IPR011978 Uncharacterised protein family UPF0149 RG49_RS00370 bf94dd6b0d29d5a0baed2911e06ec564 221 Gene3D G3DSA:3.10.450.50 187 219 1.5E-12 T 10-03-2017 IPR032710 NTF2-like domain RG49_RS00370 bf94dd6b0d29d5a0baed2911e06ec564 221 Pfam PF02810 SEC-C motif 203 220 1.7E-10 T 10-03-2017 IPR004027 SEC-C motif RG49_RS00370 bf94dd6b0d29d5a0baed2911e06ec564 221 SUPERFAMILY SSF103642 201 220 1.05E-7 T 10-03-2017 RG49_RS00370 bf94dd6b0d29d5a0baed2911e06ec564 221 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 10 182 2.8E-55 T 10-03-2017 IPR011978 Uncharacterised protein family UPF0149 RG49_RS00370 bf94dd6b0d29d5a0baed2911e06ec564 221 Pfam PF03695 Uncharacterised protein family (UPF0149) 12 183 1.7E-35 T 10-03-2017 IPR011978 Uncharacterised protein family UPF0149 RG49_RS22740 cf98279fed341ddf8a2eff0d486fdd67 463 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 180 206 2.6E-6 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22740 cf98279fed341ddf8a2eff0d486fdd67 463 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 27 51 2.6E-6 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22740 cf98279fed341ddf8a2eff0d486fdd67 463 Pfam PF00361 Proton-conducting membrane transporter 2 216 7.7E-45 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 SUPERFAMILY SSF56349 107 292 2.85E-54 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 90 1.5E-26 T 10-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 Gene3D G3DSA:1.10.443.10 115 287 1.7E-52 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 294 58.66 T 10-03-2017 IPR023009 Tyrosine recombinase XerC/XerD RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 9 296 1.9E-111 T 10-03-2017 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 Gene3D G3DSA:1.10.150.130 5 101 5.7E-25 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 Pfam PF00589 Phage integrase family 113 280 1.4E-52 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS15135 4b6949c8ccdfec49489082e4f8b4deb1 298 SUPERFAMILY SSF47823 6 98 2.16E-11 T 10-03-2017 IPR010998 Integrase, Lambda-type, N-terminal RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 8 260 4.0E-113 T 10-03-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 45 3.7E-8 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 5.0E-9 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 5 262 49.046 T 10-03-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 180 261 3.5E-29 T 10-03-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 SUPERFAMILY SSF51161 2 262 7.54E-81 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 20 48 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 PIRSF PIRSF000456 5 262 1.5E-107 T 10-03-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 Gene3D G3DSA:2.160.10.10 4 194 5.4E-51 T 10-03-2017 RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 Gene3D G3DSA:1.20.1180.10 197 262 6.1E-28 T 10-03-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 RG49_RS10910 e410512694c5bfde8a02684be2b1b62a 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 153 181 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS03040 a670594f73e3f0c5eda278e87f20b8a6 297 Gene3D G3DSA:3.10.310.10 1 125 8.3E-42 T 10-03-2017 RG49_RS03040 a670594f73e3f0c5eda278e87f20b8a6 297 Pfam PF02567 Phenazine biosynthesis-like protein 8 290 1.3E-89 T 10-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 RG49_RS03040 a670594f73e3f0c5eda278e87f20b8a6 297 PIRSF PIRSF016184 1 295 1.9E-94 T 10-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 RG49_RS03040 a670594f73e3f0c5eda278e87f20b8a6 297 SUPERFAMILY SSF54506 1 294 1.83E-66 T 10-03-2017 RG49_RS03040 a670594f73e3f0c5eda278e87f20b8a6 297 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 295 1.1E-130 T 10-03-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 RG49_RS03040 a670594f73e3f0c5eda278e87f20b8a6 297 Gene3D G3DSA:3.10.310.10 127 283 7.3E-48 T 10-03-2017 RG49_RS15870 c93eed70f90e39f40c6ab4ab0093f573 29 TIGRFAM TIGR04459 TisB_tox: type I toxin-antitoxin system toxin TisB 1 29 1.1E-17 T 10-03-2017 IPR025211 Toxin TisB, type I toxin-antitoxin system GO:0005253|GO:0005887|GO:0009432|GO:0022611 RG49_RS15870 c93eed70f90e39f40c6ab4ab0093f573 29 Pfam PF13939 Toxin TisB, type I toxin-antitoxin system 1 28 4.4E-16 T 10-03-2017 IPR025211 Toxin TisB, type I toxin-antitoxin system GO:0005253|GO:0005887|GO:0009432|GO:0022611 RG49_RS15180 099392add44afa6d872f215042a59333 246 SUPERFAMILY SSF69618 1 245 2.49E-53 T 10-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS15180 099392add44afa6d872f215042a59333 246 Gene3D G3DSA:3.40.50.10090 2 119 3.0E-10 T 10-03-2017 RG49_RS15180 099392add44afa6d872f215042a59333 246 Gene3D G3DSA:3.40.50.10090 123 245 1.1E-10 T 10-03-2017 RG49_RS15180 099392add44afa6d872f215042a59333 246 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 242 1.0E-39 T 10-03-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 RG49_RS01580 e8aa034f7c46e3a9c08cccf8602d0152 118 Pfam PF08965 Domain of unknown function (DUF1870) 1 118 3.6E-57 T 10-03-2017 IPR015060 Protein of unknown function DUF1870 RG49_RS01580 e8aa034f7c46e3a9c08cccf8602d0152 118 SUPERFAMILY SSF47413 1 118 3.26E-49 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS01580 e8aa034f7c46e3a9c08cccf8602d0152 118 Gene3D G3DSA:1.10.3100.10 1 118 1.9E-63 T 10-03-2017 IPR027910 YdiL-like domain RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 152 164 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 77 101 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 SUPERFAMILY SSF103473 15 212 4.97E-30 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 SUPERFAMILY SSF103473 257 490 4.97E-30 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 Hamap MF_01878 Dipeptide and tripeptide permease A [dtpA]. 1 489 49.555 T 10-03-2017 IPR023517 Amino acid/peptide transporter family, dipeptide and tripeptide permease A GO:0006857|GO:0015197|GO:0016020 RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 485 8.3E-139 T 10-03-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 Pfam PF00854 POT family 89 447 3.9E-94 T 10-03-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 Gene3D G3DSA:1.20.1250.20 21 202 1.1E-17 T 10-03-2017 RG49_RS01875 2b1640b515824ed518d0b62beef78d1c 500 Gene3D G3DSA:1.20.1250.20 274 487 3.4E-9 T 10-03-2017 RG49_RS24695 f5b5bd25d1f3bbc62cf55475dfb9a5e9 425 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 418 1.5E-197 T 10-03-2017 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 RG49_RS24695 f5b5bd25d1f3bbc62cf55475dfb9a5e9 425 Pfam PF03825 Nucleoside H+ symporter 1 405 7.8E-186 T 10-03-2017 RG49_RS24695 f5b5bd25d1f3bbc62cf55475dfb9a5e9 425 Gene3D G3DSA:1.20.1250.20 5 189 1.3E-14 T 10-03-2017 RG49_RS24695 f5b5bd25d1f3bbc62cf55475dfb9a5e9 425 SUPERFAMILY SSF103473 6 404 2.75E-41 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS24695 f5b5bd25d1f3bbc62cf55475dfb9a5e9 425 Gene3D G3DSA:1.20.1250.20 202 406 5.9E-25 T 10-03-2017 RG49_RS07930 9619fb5669adb8b1a2ab49236511e1c7 633 Gene3D G3DSA:3.40.710.10 253 612 4.5E-99 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS07930 9619fb5669adb8b1a2ab49236511e1c7 633 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 239 6.6E-46 T 10-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 RG49_RS07930 9619fb5669adb8b1a2ab49236511e1c7 633 SUPERFAMILY SSF56519 56 253 1.31E-53 T 10-03-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 RG49_RS07930 9619fb5669adb8b1a2ab49236511e1c7 633 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 19 612 6.8E-240 T 10-03-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 RG49_RS07930 9619fb5669adb8b1a2ab49236511e1c7 633 Gene3D G3DSA:3.90.1310.10 130 252 5.9E-41 T 10-03-2017 RG49_RS07930 9619fb5669adb8b1a2ab49236511e1c7 633 SUPERFAMILY SSF56601 254 611 2.47E-91 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS07930 9619fb5669adb8b1a2ab49236511e1c7 633 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 609 9.7E-86 T 10-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 RG49_RS00760 e708932f428e492d622bf17d2525c519 218 SUPERFAMILY SSF56300 17 217 1.32E-42 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS00760 e708932f428e492d622bf17d2525c519 218 Gene3D G3DSA:3.60.21.10 9 218 3.5E-45 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS00760 e708932f428e492d622bf17d2525c519 218 Pfam PF00149 Calcineurin-like phosphoesterase 18 162 3.5E-12 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS00760 e708932f428e492d622bf17d2525c519 218 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 76 81 - T 10-03-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 RG49_RS23570 9a5315fcb6bb866a2abd9ab28f13a3d9 215 Gene3D G3DSA:1.20.1050.10 84 198 1.7E-48 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS23570 9a5315fcb6bb866a2abd9ab28f13a3d9 215 SUPERFAMILY SSF47616 78 201 3.96E-34 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS23570 9a5315fcb6bb866a2abd9ab28f13a3d9 215 Pfam PF00043 Glutathione S-transferase, C-terminal domain 135 197 9.5E-11 T 10-03-2017 IPR004046 Glutathione S-transferase, C-terminal RG49_RS23570 9a5315fcb6bb866a2abd9ab28f13a3d9 215 Gene3D G3DSA:3.40.30.10 1 83 2.3E-26 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS23570 9a5315fcb6bb866a2abd9ab28f13a3d9 215 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 81 1.8E-13 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS23570 9a5315fcb6bb866a2abd9ab28f13a3d9 215 SUPERFAMILY SSF52833 1 84 3.32E-21 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 Pfam PF00871 Acetokinase family 6 393 4.5E-178 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 Gene3D G3DSA:3.30.420.40 208 398 7.4E-74 T 10-03-2017 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 SUPERFAMILY SSF53067 4 199 3.17E-63 T 10-03-2017 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 Hamap MF_00020 Acetate kinase [ackA]. 1 400 185.948 T 10-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 10-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 206 223 - T 10-03-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 TIGRFAM TIGR00016 ackA: acetate kinase 1 399 9.7E-188 T 10-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 PIRSF PIRSF000722 2 400 4.5E-143 T 10-03-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 Gene3D G3DSA:3.30.420.40 5 207 7.5E-10 T 10-03-2017 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 SUPERFAMILY SSF53067 160 398 6.02E-84 T 10-03-2017 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 PRINTS PR00471 Acetate kinase family signature 6 17 2.3E-48 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 PRINTS PR00471 Acetate kinase family signature 325 341 2.3E-48 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 PRINTS PR00471 Acetate kinase family signature 302 315 2.3E-48 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 PRINTS PR00471 Acetate kinase family signature 176 189 2.3E-48 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 PRINTS PR00471 Acetate kinase family signature 206 227 2.3E-48 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS23600 d3380e9e3ca970d9dfbed22064b59906 400 PRINTS PR00471 Acetate kinase family signature 380 392 2.3E-48 T 10-03-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 RG49_RS02450 1094f8439d83dad3636edbb27c6f465e 232 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 12 230 5.8E-99 T 10-03-2017 IPR006487 Bacteriophage lambda, GpL, minor tail RG49_RS02450 1094f8439d83dad3636edbb27c6f465e 232 Pfam PF05100 Phage minor tail protein L 29 230 1.2E-96 T 10-03-2017 IPR006487 Bacteriophage lambda, GpL, minor tail RG49_RS04245 ba0f52f1dd09d9a0cc84f88a72b1cda3 631 Pfam PF09972 Predicted membrane protein (DUF2207) 35 572 1.4E-69 T 10-03-2017 IPR018702 Protein of unknown function DUF2207, membrane RG49_RS00500 308c2c704e7f4631f2bcb6223796b8cb 129 Gene3D G3DSA:3.40.50.2300 4 126 2.8E-38 T 10-03-2017 RG49_RS00500 308c2c704e7f4631f2bcb6223796b8cb 129 SMART SM00448 6 120 8.9E-35 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00500 308c2c704e7f4631f2bcb6223796b8cb 129 Pfam PF00072 Response regulator receiver domain 9 120 6.1E-32 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00500 308c2c704e7f4631f2bcb6223796b8cb 129 SUPERFAMILY SSF52172 5 125 1.85E-35 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Gene3D G3DSA:3.30.70.240 610 696 3.0E-32 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 10-03-2017 IPR031157 Tr-type G domain, conserved site RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 SUPERFAMILY SSF52540 6 288 1.2E-106 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 SMART SM00889 487 609 1.4E-72 T 10-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Gene3D G3DSA:3.30.70.870 413 487 7.9E-39 T 10-03-2017 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Pfam PF14492 Elongation Factor G, domain II 411 485 7.8E-34 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Gene3D G3DSA:2.40.30.10 312 412 6.1E-38 T 10-03-2017 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 SMART SM00838 611 698 3.9E-50 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Pfam PF03764 Elongation factor G, domain IV 486 609 1.9E-45 T 10-03-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Gene3D G3DSA:3.40.50.300 7 293 5.1E-104 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 187 7.0E-32 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 SUPERFAMILY SSF54211 486 610 9.1E-41 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 703 0.0 T 10-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Hamap MF_00054_B Elongation factor G [fusA]. 6 702 112.335 T 10-03-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 SUPERFAMILY SSF54980 411 488 3.02E-25 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 SUPERFAMILY SSF50447 271 411 3.76E-35 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Pfam PF03144 Elongation factor Tu domain 2 331 398 5.1E-16 T 10-03-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Pfam PF00679 Elongation factor G C-terminus 611 696 6.7E-29 T 10-03-2017 IPR000640 Translation elongation factor EFG, V domain RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.7E-16 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.7E-16 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.7E-16 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.7E-16 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.7E-16 T 10-03-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 3.8E-68 T 10-03-2017 RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 Gene3D G3DSA:3.30.230.10 491 609 9.4E-47 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS17905 5ed92216217cffcadf103a2d101359d4 704 SUPERFAMILY SSF54980 611 700 2.84E-27 T 10-03-2017 IPR009022 Elongation factor G, III-V domain RG49_RS04610 1acea1fd8e0a35126912722cba9822e3 194 SUPERFAMILY SSF53178 3 192 8.11E-71 T 10-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 RG49_RS04610 1acea1fd8e0a35126912722cba9822e3 194 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 110 120 - T 10-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 RG49_RS04610 1acea1fd8e0a35126912722cba9822e3 194 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 10-03-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 RG49_RS04610 1acea1fd8e0a35126912722cba9822e3 194 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 182 36.382 T 10-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 RG49_RS04610 1acea1fd8e0a35126912722cba9822e3 194 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 189 2.6E-74 T 10-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 RG49_RS04610 1acea1fd8e0a35126912722cba9822e3 194 Pfam PF01195 Peptidyl-tRNA hydrolase 5 187 9.7E-54 T 10-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 RG49_RS04610 1acea1fd8e0a35126912722cba9822e3 194 Gene3D G3DSA:3.40.50.1470 3 192 4.1E-72 T 10-03-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 RG49_RS14120 019bd924500663844264e3327cfd671f 211 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 20 202 8.2E-59 T 10-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS14120 019bd924500663844264e3327cfd671f 211 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 207 19.906 T 10-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS14120 019bd924500663844264e3327cfd671f 211 Gene3D G3DSA:3.20.20.70 6 204 5.7E-67 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS14120 019bd924500663844264e3327cfd671f 211 Pfam PF02581 Thiamine monophosphate synthase/TENI 20 189 6.1E-56 T 10-03-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS14120 019bd924500663844264e3327cfd671f 211 SUPERFAMILY SSF51391 6 205 1.01E-63 T 10-03-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS16600 569cf1feac98281f8232aeb1a75b1cc6 274 SMART SM00047 127 256 9.6E-42 T 10-03-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 RG49_RS16600 569cf1feac98281f8232aeb1a75b1cc6 274 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 142 267 2.0E-16 T 10-03-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 RG49_RS08435 d1dd424a617301efaba91e7c373fab8b 77 SUPERFAMILY SSF55174 6 76 4.19E-20 T 10-03-2017 RG49_RS08435 d1dd424a617301efaba91e7c373fab8b 77 Pfam PF13275 S4 domain 16 76 1.1E-23 T 10-03-2017 RG49_RS08435 d1dd424a617301efaba91e7c373fab8b 77 Gene3D G3DSA:3.10.290.10 3 76 2.0E-28 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS00920 3ecc229e111a2dda5f13f13566d72467 59 Pfam PF03701 Uncharacterised protein family (UPF0181) 1 49 6.8E-29 T 10-03-2017 IPR005371 Uncharacterised protein family UPF0181 RG49_RS00920 3ecc229e111a2dda5f13f13566d72467 59 Hamap MF_00507 UPF0181 protein YoaH [yoaH]. 1 58 20.866 T 10-03-2017 IPR005371 Uncharacterised protein family UPF0181 RG49_RS00920 3ecc229e111a2dda5f13f13566d72467 59 ProDom PD026807 UPF0181 YOAH YPTB1650 VV20310 VPA0916 VCA0569 YPO1774/Y2534/YP1619 PLU2693 VVA0806 PM0480 1 48 2.0E-20 T 10-03-2017 IPR005371 Uncharacterised protein family UPF0181 RG49_RS16845 137501c766bb7ae96289be839fdfbbc5 250 Gene3D G3DSA:3.40.50.300 10 236 3.5E-26 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16845 137501c766bb7ae96289be839fdfbbc5 250 SUPERFAMILY SSF52540 3 235 9.95E-27 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16845 137501c766bb7ae96289be839fdfbbc5 250 TIGRFAM TIGR03371 cellulose_yhjQ: cellulose synthase operon protein YhjQ 1 239 1.7E-89 T 10-03-2017 IPR017746 Cellulose synthase operon protein BcsQ RG49_RS16845 137501c766bb7ae96289be839fdfbbc5 250 Pfam PF06564 Cellulose biosynthesis protein BcsQ 1 236 3.4E-109 T 10-03-2017 IPR017746 Cellulose synthase operon protein BcsQ RG49_RS11535 8b33dd0db12f5a412e8477e3e43f9004 232 SUPERFAMILY SSF52540 1 222 2.54E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11535 8b33dd0db12f5a412e8477e3e43f9004 232 SMART SM00382 24 209 1.4E-19 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS11535 8b33dd0db12f5a412e8477e3e43f9004 232 Gene3D G3DSA:3.40.50.300 17 224 4.8E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11535 8b33dd0db12f5a412e8477e3e43f9004 232 Pfam PF00005 ABC transporter 18 157 2.5E-37 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS11535 8b33dd0db12f5a412e8477e3e43f9004 232 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS11535 8b33dd0db12f5a412e8477e3e43f9004 232 TIGRFAM TIGR01277 thiQ: thiamine ABC transporter, ATP-binding protein 2 214 8.3E-120 T 10-03-2017 IPR005968 Thiamine ABC transporter, ATP-binding protein ThiQ GO:0005524|GO:0006810|GO:0016021|GO:0042626 RG49_RS11450 caf26526566e5443399fb4a9b79e8df5 152 Pfam PF02381 MraZ protein, putative antitoxin-like 77 135 2.7E-21 T 10-03-2017 IPR020603 MraZ domain RG49_RS11450 caf26526566e5443399fb4a9b79e8df5 152 Pfam PF02381 MraZ protein, putative antitoxin-like 1 75 1.1E-25 T 10-03-2017 IPR020603 MraZ domain RG49_RS11450 caf26526566e5443399fb4a9b79e8df5 152 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 152 58.628 T 10-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 RG49_RS11450 caf26526566e5443399fb4a9b79e8df5 152 SUPERFAMILY SSF89447 1 135 1.26E-45 T 10-03-2017 RG49_RS11450 caf26526566e5443399fb4a9b79e8df5 152 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 152 1.9E-68 T 10-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 RG49_RS11450 caf26526566e5443399fb4a9b79e8df5 152 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 139 2.0E-78 T 10-03-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 RG49_RS01295 ea37cb76b651f90db9b8d4dbf6861145 275 Pfam PF02540 NAD synthase 23 265 1.5E-81 T 10-03-2017 IPR022310 NAD/GMP synthase RG49_RS01295 ea37cb76b651f90db9b8d4dbf6861145 275 Gene3D G3DSA:3.40.50.620 4 269 2.3E-67 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS01295 ea37cb76b651f90db9b8d4dbf6861145 275 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 268 31.355 T 10-03-2017 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 RG49_RS01295 ea37cb76b651f90db9b8d4dbf6861145 275 SUPERFAMILY SSF52402 3 273 1.45E-86 T 10-03-2017 RG49_RS01295 ea37cb76b651f90db9b8d4dbf6861145 275 TIGRFAM TIGR00552 nadE: NAD+ synthetase 16 275 8.1E-88 T 10-03-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 RG49_RS24840 3c91311e90e18c90f19322863839383f 282 Gene3D G3DSA:1.10.1670.10 231 281 1.3E-20 T 10-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 RG49_RS24840 3c91311e90e18c90f19322863839383f 282 SUPERFAMILY SSF48150 102 274 5.41E-49 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS24840 3c91311e90e18c90f19322863839383f 282 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 118 240 7.1E-10 T 10-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 RG49_RS24840 3c91311e90e18c90f19322863839383f 282 Gene3D G3DSA:3.30.310.20 2 112 3.9E-36 T 10-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal RG49_RS24840 3c91311e90e18c90f19322863839383f 282 Gene3D G3DSA:1.10.340.30 113 229 1.8E-38 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS24840 3c91311e90e18c90f19322863839383f 282 SUPERFAMILY SSF55945 2 98 7.53E-29 T 10-03-2017 RG49_RS24840 3c91311e90e18c90f19322863839383f 282 Pfam PF06029 AlkA N-terminal domain 3 112 2.7E-28 T 10-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal RG49_RS24840 3c91311e90e18c90f19322863839383f 282 SMART SM00478 130 276 4.1E-34 T 10-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 RG49_RS24840 3c91311e90e18c90f19322863839383f 282 SMART SM01009 1 112 2.7E-48 T 10-03-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal RG49_RS24840 3c91311e90e18c90f19322863839383f 282 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 214 238 - T 10-03-2017 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 RG49_RS05285 038013067a4259ba701397125f92a597 219 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 84 217 3.5E-37 T 10-03-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal RG49_RS05285 038013067a4259ba701397125f92a597 219 Pfam PF13144 Chaperone for flagella basal body P-ring formation 26 215 1.2E-37 T 10-03-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal RG49_RS05285 038013067a4259ba701397125f92a597 219 SMART SM00858 95 157 7.1E-9 T 10-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 RG49_RS21050 a7952e210195e398156a0d5896aa0437 382 TIGRFAM TIGR02638 lactal_redase: lactaldehyde reductase 2 378 1.4E-200 T 10-03-2017 IPR013460 Lactaldehyde reductase KEGG: 00630+1.1.1.77|KEGG: 00640+1.1.1.77 RG49_RS21050 a7952e210195e398156a0d5896aa0437 382 Gene3D G3DSA:3.40.50.1970 4 185 1.7E-58 T 10-03-2017 RG49_RS21050 a7952e210195e398156a0d5896aa0437 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 374 2.1E-117 T 10-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 RG49_RS21050 a7952e210195e398156a0d5896aa0437 382 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS21050 a7952e210195e398156a0d5896aa0437 382 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 259 279 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS21050 a7952e210195e398156a0d5896aa0437 382 SUPERFAMILY SSF56796 7 382 1.57E-124 T 10-03-2017 RG49_RS21050 a7952e210195e398156a0d5896aa0437 382 Gene3D G3DSA:1.20.1090.10 186 382 2.0E-72 T 10-03-2017 RG49_RS06890 b41212aa0c737d7fdae9fef1beeb3ead 810 ProSitePatterns PS00850 Glycine radical domain signature. 781 789 - T 10-03-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site RG49_RS06890 b41212aa0c737d7fdae9fef1beeb3ead 810 Pfam PF01228 Glycine radical 688 791 2.9E-30 T 10-03-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 RG49_RS06890 b41212aa0c737d7fdae9fef1beeb3ead 810 SUPERFAMILY SSF51998 7 808 4.27E-233 T 10-03-2017 RG49_RS06890 b41212aa0c737d7fdae9fef1beeb3ead 810 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 8 810 0.0 T 10-03-2017 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 RG49_RS06890 b41212aa0c737d7fdae9fef1beeb3ead 810 PIRSF PIRSF000379 55 810 5.4E-200 T 10-03-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 RG49_RS06890 b41212aa0c737d7fdae9fef1beeb3ead 810 Gene3D G3DSA:3.20.70.20 8 808 1.5E-269 T 10-03-2017 RG49_RS06890 b41212aa0c737d7fdae9fef1beeb3ead 810 Pfam PF02901 Pyruvate formate lyase-like 10 671 7.2E-213 T 10-03-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 RG49_RS16595 2fe9051acc0d44d5b01da336b1507415 676 SUPERFAMILY SSF51445 374 643 1.59E-73 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS16595 2fe9051acc0d44d5b01da336b1507415 676 SUPERFAMILY SSF51445 179 318 1.59E-73 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS16595 2fe9051acc0d44d5b01da336b1507415 676 SMART SM00642 193 637 6.0E-87 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS16595 2fe9051acc0d44d5b01da336b1507415 676 PIRSF PIRSF036917 1 676 0.0 T 10-03-2017 IPR014635 Alpha-amylase, MalS type GO:0004556|GO:0005509|GO:0030980|GO:0042597|GO:0051692 KEGG: 00500+3.2.1.1 RG49_RS16595 2fe9051acc0d44d5b01da336b1507415 676 Gene3D G3DSA:3.20.20.80 183 644 2.9E-86 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS16595 2fe9051acc0d44d5b01da336b1507415 676 Pfam PF00128 Alpha amylase, catalytic domain 226 594 2.9E-37 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS05590 1b132ebafe918ddb07ad91bf691ba8ce 423 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 61 410 2.7E-108 T 10-03-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 RG49_RS05590 1b132ebafe918ddb07ad91bf691ba8ce 423 SUPERFAMILY SSF54909 54 416 6.08E-99 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS05590 1b132ebafe918ddb07ad91bf691ba8ce 423 Pfam PF04261 Dyp-type peroxidase family 61 410 6.7E-122 T 10-03-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 RG49_RS05590 1b132ebafe918ddb07ad91bf691ba8ce 423 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 6 422 2.5E-186 T 10-03-2017 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 RG49_RS06145 4958103bc71341f7156bffe93334285c 248 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 248 46.689 T 10-03-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 RG49_RS06145 4958103bc71341f7156bffe93334285c 248 SUPERFAMILY SSF53448 3 245 8.11E-68 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS06145 4958103bc71341f7156bffe93334285c 248 Gene3D G3DSA:3.90.550.10 1 247 5.4E-86 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS06145 4958103bc71341f7156bffe93334285c 248 Pfam PF02348 Cytidylyltransferase 4 221 1.0E-73 T 10-03-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 RG49_RS06145 4958103bc71341f7156bffe93334285c 248 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 241 1.3E-138 T 10-03-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 RG49_RS03540 2ce28f8d2c735cd6eef7ac6b1d1e1ef8 144 Pfam PF00582 Universal stress protein family 1 144 6.6E-30 T 10-03-2017 IPR006016 UspA GO:0006950 RG49_RS03540 2ce28f8d2c735cd6eef7ac6b1d1e1ef8 144 SUPERFAMILY SSF52402 3 144 5.11E-31 T 10-03-2017 RG49_RS03540 2ce28f8d2c735cd6eef7ac6b1d1e1ef8 144 Gene3D G3DSA:3.40.50.620 3 144 5.4E-35 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS03540 2ce28f8d2c735cd6eef7ac6b1d1e1ef8 144 PRINTS PR01438 Universal stress protein signature 105 117 7.3E-9 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS03540 2ce28f8d2c735cd6eef7ac6b1d1e1ef8 144 PRINTS PR01438 Universal stress protein signature 2 20 7.3E-9 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS03540 2ce28f8d2c735cd6eef7ac6b1d1e1ef8 144 PRINTS PR01438 Universal stress protein signature 122 144 7.3E-9 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS02690 2f0b977a261828b862c4c1ee7729a7fa 453 Pfam PF00589 Phage integrase family 209 363 4.5E-6 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02690 2f0b977a261828b862c4c1ee7729a7fa 453 Gene3D G3DSA:1.10.443.10 178 365 3.1E-12 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02690 2f0b977a261828b862c4c1ee7729a7fa 453 SUPERFAMILY SSF56349 178 365 3.24E-13 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS03060 805f6b3fcf323ecfb77d41d35e5c7659 378 Pfam PF01609 Transposase DDE domain 102 343 1.1E-30 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS03060 805f6b3fcf323ecfb77d41d35e5c7659 378 Pfam PF13808 DDE_Tnp_1-associated 7 94 5.6E-33 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS18425 d2b5373f399cc0382ddf0dc559a2c9ab 90 Gene3D G3DSA:3.30.370.10 1 85 6.8E-14 T 10-03-2017 IPR000468 Barstar (barnase inhibitor) RG49_RS18425 d2b5373f399cc0382ddf0dc559a2c9ab 90 SUPERFAMILY SSF52038 1 89 3.79E-29 T 10-03-2017 IPR000468 Barstar (barnase inhibitor) RG49_RS18425 d2b5373f399cc0382ddf0dc559a2c9ab 90 Pfam PF01337 Barstar (barnase inhibitor) 5 79 5.1E-5 T 10-03-2017 IPR000468 Barstar (barnase inhibitor) RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 SUPERFAMILY SSF50331 239 345 7.37E-14 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 243 4.9E-129 T 10-03-2017 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 Pfam PF12857 TOBE-like domain 289 339 1.9E-7 T 10-03-2017 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 Gene3D G3DSA:3.40.50.300 3 244 7.1E-83 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 SMART SM00382 27 214 3.2E-18 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 SUPERFAMILY SSF52540 3 244 9.13E-86 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 Pfam PF00005 ABC transporter 18 164 4.8E-38 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS23015 eebe6746730e1289ce3d1cce1159eed6 365 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 Gene3D G3DSA:3.40.50.2030 234 379 3.7E-65 T 10-03-2017 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 PIRSF PIRSF000076 1 550 4.5E-241 T 10-03-2017 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 Gene3D G3DSA:1.20.1270.20 1 158 6.2E-38 T 10-03-2017 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 548 3.3E-231 T 10-03-2017 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 549 21.657 T 10-03-2017 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 Pfam PF03063 Prismane/CO dehydrogenase family 1 545 2.0E-156 T 10-03-2017 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 SUPERFAMILY SSF56821 1 548 2.49E-190 T 10-03-2017 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 Gene3D G3DSA:3.40.50.2030 380 547 1.3E-68 T 10-03-2017 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS06395 97f76dcbb43aa9cfd949ecf15a5341ac 550 Gene3D G3DSA:1.20.1270.20 159 232 4.3E-26 T 10-03-2017 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 Gene3D G3DSA:3.30.70.20 38 116 9.4E-25 T 10-03-2017 RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 Gene3D G3DSA:3.30.70.20 188 229 9.4E-25 T 10-03-2017 RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 145 156 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 SUPERFAMILY SSF54862 38 325 1.26E-71 T 10-03-2017 RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 1 26 3.1E-4 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 Pfam PF13247 4Fe-4S dicluster domain 105 207 5.1E-23 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 Gene3D G3DSA:3.30.70.20 117 149 3.0E-12 T 10-03-2017 RG49_RS19780 04bfd607f5520a0d8acc0f14da11b792 328 Gene3D G3DSA:3.30.70.20 150 187 4.7E-9 T 10-03-2017 RG49_RS04555 d63d61068f94d5289d7c8b5c6079f26a 284 Gene3D G3DSA:3.20.20.70 18 281 1.1E-108 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS04555 d63d61068f94d5289d7c8b5c6079f26a 284 SUPERFAMILY SSF51569 3 278 1.1E-103 T 10-03-2017 RG49_RS04555 d63d61068f94d5289d7c8b5c6079f26a 284 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 275 1.0E-118 T 10-03-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS04555 d63d61068f94d5289d7c8b5c6079f26a 284 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 277 50.268 T 10-03-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS04555 d63d61068f94d5289d7c8b5c6079f26a 284 Pfam PF00793 DAHP synthetase I family 10 274 2.0E-68 T 10-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 1.1E-67 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 88 98 1.1E-67 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 277 290 1.1E-67 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 1.1E-67 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 329 344 1.1E-67 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 254 272 1.1E-67 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 1.1E-67 T 10-03-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 SUPERFAMILY SSF53822 24 364 4.12E-91 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 Gene3D G3DSA:3.40.50.2300 24 224 1.1E-65 T 10-03-2017 RG49_RS17285 282fe335fbf6ed4a93ac54316d4aedd5 369 Pfam PF13458 Periplasmic binding protein 26 363 2.6E-62 T 10-03-2017 IPR028081 Leucine-binding protein domain RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Gene3D G3DSA:2.40.50.140 347 421 3.9E-23 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Pfam PF00912 Transglycosylase 55 229 5.6E-65 T 10-03-2017 IPR001264 Glycosyl transferase, family 51 RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Gene3D G3DSA:1.10.3810.10 55 231 7.5E-76 T 10-03-2017 RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Gene3D G3DSA:3.40.710.10 422 611 5.7E-132 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Gene3D G3DSA:3.40.710.10 673 831 5.7E-132 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Gene3D G3DSA:3.40.710.10 232 313 5.7E-132 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 SUPERFAMILY SSF56601 422 610 1.79E-111 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 SUPERFAMILY SSF56601 211 233 1.79E-111 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 SUPERFAMILY SSF56601 672 832 1.79E-111 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 SUPERFAMILY SSF56601 262 313 1.79E-111 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Pfam PF00905 Penicillin binding protein transpeptidase domain 429 611 2.3E-24 T 10-03-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 758 9.1E-174 T 10-03-2017 RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 Pfam PF17092 Penicillin-binding protein OB-like domain 316 425 1.9E-31 T 10-03-2017 IPR031376 Penicillin-binding protein, OB-like domain RG49_RS17605 ebe13cf1bc8ed92ec346c9e20c2252a6 850 SUPERFAMILY SSF53955 43 256 1.69E-80 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 196 33.165 T 10-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 196 9.7E-75 T 10-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 SUPERFAMILY SSF52317 3 195 7.91E-53 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 Gene3D G3DSA:3.40.50.880 1 196 5.1E-70 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 72 83 9.7E-5 T 10-03-2017 RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 174 187 9.7E-5 T 10-03-2017 RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 Pfam PF00117 Glutamine amidotransferase class-I 7 194 1.6E-17 T 10-03-2017 IPR017926 Glutamine amidotransferase RG49_RS25085 238e25162c0a2ea5ef8b1029e602d964 196 PIRSF PIRSF000495 1 196 2.5E-62 T 10-03-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 RG49_RS24765 dd071b74c71eed80ca76002178124ad2 453 Pfam PF01136 Peptidase family U32 75 343 4.9E-97 T 10-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 RG49_RS24765 dd071b74c71eed80ca76002178124ad2 453 ProSitePatterns PS01276 Peptidase family U32 signature. 162 180 - T 10-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 RG49_RS24765 dd071b74c71eed80ca76002178124ad2 453 Pfam PF16325 Peptidase family U32 C-terminal domain 359 440 3.4E-20 T 10-03-2017 IPR032525 Peptidase family U32, C-terminal RG49_RS11155 ed772fa64830eb1cfb7779cbebe0a171 200 SUPERFAMILY SSF49401 43 200 7.46E-17 T 10-03-2017 IPR008966 Adhesion domain RG49_RS11155 ed772fa64830eb1cfb7779cbebe0a171 200 Gene3D G3DSA:2.60.40.1090 43 200 2.9E-12 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11155 ed772fa64830eb1cfb7779cbebe0a171 200 Pfam PF00419 Fimbrial protein 44 199 5.1E-11 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12235 84b08ee7343ebc1810ef966685c0e9c3 170 SMART SM00903 14 161 5.2E-43 T 10-03-2017 IPR002563 Flavin reductase like domain GO:0010181 RG49_RS12235 84b08ee7343ebc1810ef966685c0e9c3 170 Gene3D G3DSA:2.30.110.10 7 160 3.3E-46 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS12235 84b08ee7343ebc1810ef966685c0e9c3 170 SUPERFAMILY SSF50475 9 162 1.18E-43 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS12235 84b08ee7343ebc1810ef966685c0e9c3 170 TIGRFAM TIGR02296 HpaC: 4-hydroxyphenylacetate 3-monooxygenase, reductase component 10 163 7.7E-81 T 10-03-2017 IPR011982 4-hydroxyphenylacetate 3-monooxygenase, reductase component GO:0016651|GO:0042537|GO:0051287|GO:0055114 RG49_RS12235 84b08ee7343ebc1810ef966685c0e9c3 170 Pfam PF01613 Flavin reductase like domain 14 162 7.6E-25 T 10-03-2017 IPR002563 Flavin reductase like domain GO:0010181 RG49_RS01735 b2db91741e661fc80a2b14f173ab7a45 403 Gene3D G3DSA:1.20.1250.20 7 189 6.7E-30 T 10-03-2017 RG49_RS01735 b2db91741e661fc80a2b14f173ab7a45 403 SUPERFAMILY SSF103473 5 379 1.31E-59 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01735 b2db91741e661fc80a2b14f173ab7a45 403 Gene3D G3DSA:1.20.1250.20 200 377 1.1E-13 T 10-03-2017 RG49_RS01735 b2db91741e661fc80a2b14f173ab7a45 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 3 382 3.5E-148 T 10-03-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 RG49_RS01735 b2db91741e661fc80a2b14f173ab7a45 403 Pfam PF07690 Major Facilitator Superfamily 14 341 9.3E-43 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS14810 a166172673f2b331f65aeb86c52e0a66 326 SUPERFAMILY SSF51658 37 260 8.34E-20 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS14810 a166172673f2b331f65aeb86c52e0a66 326 Pfam PF01261 Xylose isomerase-like TIM barrel 41 212 4.7E-11 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS14810 a166172673f2b331f65aeb86c52e0a66 326 Gene3D G3DSA:3.20.20.150 37 242 3.1E-28 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS22930 e1ee55ce3097f70786b5c3d8643f6bcf 219 SUPERFAMILY SSF143414 158 211 1.83E-5 T 10-03-2017 RG49_RS22930 e1ee55ce3097f70786b5c3d8643f6bcf 219 PIRSF PIRSF012290 1 219 8.6E-85 T 10-03-2017 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 RG49_RS22930 e1ee55ce3097f70786b5c3d8643f6bcf 219 Pfam PF00936 BMC domain 160 208 8.5E-6 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22930 e1ee55ce3097f70786b5c3d8643f6bcf 219 Pfam PF00936 BMC domain 36 107 4.2E-11 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22930 e1ee55ce3097f70786b5c3d8643f6bcf 219 SMART SM00877 35 110 8.2E-4 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22930 e1ee55ce3097f70786b5c3d8643f6bcf 219 SMART SM00877 146 219 2.2E-6 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22930 e1ee55ce3097f70786b5c3d8643f6bcf 219 TIGRFAM TIGR04502 microcomp_EutL: microcompartment protein EutL 6 217 6.1E-101 T 10-03-2017 IPR030983 Ethanolamine utilization protein EutL GO:0005198 RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 SUPERFAMILY SSF53720 5 500 1.31E-78 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 Gene3D G3DSA:3.40.605.10 3 286 2.1E-32 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 Pfam PF01575 MaoC like domain 536 650 4.2E-32 T 10-03-2017 IPR002539 MaoC-like domain RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 Pfam PF00171 Aldehyde dehydrogenase family 24 498 5.5E-61 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 4 674 0.0 T 10-03-2017 IPR011966 Phenylacetic acid degradation protein PaaN RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 Gene3D G3DSA:3.40.309.10 287 441 1.6E-34 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 SUPERFAMILY SSF54637 525 676 2.02E-37 T 10-03-2017 IPR029069 HotDog domain RG49_RS03460 f556312b2811bbc6c8dd58fce09c221c 681 Gene3D G3DSA:3.10.129.10 521 676 1.3E-44 T 10-03-2017 IPR029069 HotDog domain RG49_RS09740 c27c5dfc8e2715739374311029a2ae94 200 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 78 199 5.3E-25 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS09785 c27c5dfc8e2715739374311029a2ae94 200 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 78 199 5.3E-25 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS00455 9255e821eaaa6d147395623e6dd34ac2 192 PIRSF PIRSF003159 1 181 1.4E-91 T 10-03-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 RG49_RS00455 9255e821eaaa6d147395623e6dd34ac2 192 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 186 45.375 T 10-03-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 RG49_RS00455 9255e821eaaa6d147395623e6dd34ac2 192 SUPERFAMILY SSF160930 5 160 3.01E-64 T 10-03-2017 RG49_RS00455 9255e821eaaa6d147395623e6dd34ac2 192 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 192 3.0E-110 T 10-03-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 RG49_RS00455 9255e821eaaa6d147395623e6dd34ac2 192 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 172 1.1E-81 T 10-03-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 Gene3D G3DSA:3.40.640.10 63 314 1.6E-87 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 Gene3D G3DSA:3.90.1150.10 315 470 1.1E-63 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 PIRSF PIRSF001386 3 471 5.2E-202 T 10-03-2017 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 260 278 - T 10-03-2017 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 TIGRFAM TIGR02617 tnaA_trp_ase: tryptophanase 5 471 0.0 T 10-03-2017 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 Pfam PF01212 Beta-eliminating lyase 49 437 9.8E-92 T 10-03-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 Hamap MF_00544 Tryptophanase [tnaA]. 4 471 102.324 T 10-03-2017 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 RG49_RS15675 c1c007e5cd0f0bdd10897ed8ba9a91b9 471 SUPERFAMILY SSF53383 6 471 1.94E-128 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS04955 df52ec73cacdfbba1e905ec5b1e1011e 223 SMART SM00448 1 112 5.6E-38 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS04955 df52ec73cacdfbba1e905ec5b1e1011e 223 Pfam PF00072 Response regulator receiver domain 3 112 2.5E-25 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS04955 df52ec73cacdfbba1e905ec5b1e1011e 223 Gene3D G3DSA:3.40.50.2300 1 122 5.9E-35 T 10-03-2017 RG49_RS04955 df52ec73cacdfbba1e905ec5b1e1011e 223 SMART SM00862 145 220 2.2E-19 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS04955 df52ec73cacdfbba1e905ec5b1e1011e 223 SUPERFAMILY SSF52172 1 173 1.14E-37 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS04955 df52ec73cacdfbba1e905ec5b1e1011e 223 Gene3D G3DSA:1.10.10.10 124 221 1.8E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04955 df52ec73cacdfbba1e905ec5b1e1011e 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 7.1E-20 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS21115 5940cf256bc06dacd1577f508626a1c1 446 TIGRFAM TIGR03247 glucar-dehydr: glucarate dehydratase 6 446 1.1E-271 T 10-03-2017 IPR017653 Glucarate dehydratase GO:0000287|GO:0008872|GO:0019394 KEGG: 00053+4.2.1.40|MetaCyc: PWY-6499 RG49_RS21115 5940cf256bc06dacd1577f508626a1c1 446 SUPERFAMILY SSF51604 139 415 1.43E-81 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS21115 5940cf256bc06dacd1577f508626a1c1 446 Gene3D G3DSA:3.20.20.120 119 398 3.4E-101 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS21115 5940cf256bc06dacd1577f508626a1c1 446 Gene3D G3DSA:3.30.390.10 11 118 7.7E-8 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21115 5940cf256bc06dacd1577f508626a1c1 446 SMART SM00922 185 285 5.1E-16 T 10-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal RG49_RS21115 5940cf256bc06dacd1577f508626a1c1 446 Pfam PF13378 Enolase C-terminal domain-like 189 405 2.8E-37 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS21115 5940cf256bc06dacd1577f508626a1c1 446 SUPERFAMILY SSF54826 8 137 6.89E-30 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS04690 39d3c02d553720ba2f5014dc34a7ec45 203 Hamap MF_01381 Endo-type membrane-bound lytic murein transglycosylase A [emtA]. 1 203 68.25 T 10-03-2017 IPR023946 Endo-type membrane-bound lytic murein transglycosylase A GO:0008932|GO:0009279|GO:0016837|GO:0016998 RG49_RS04690 39d3c02d553720ba2f5014dc34a7ec45 203 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 60 88 - T 10-03-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 RG49_RS04690 39d3c02d553720ba2f5014dc34a7ec45 203 Pfam PF01464 Transglycosylase SLT domain 43 168 5.7E-29 T 10-03-2017 IPR008258 Transglycosylase SLT domain 1 RG49_RS04690 39d3c02d553720ba2f5014dc34a7ec45 203 Gene3D G3DSA:1.10.530.10 34 198 2.3E-30 T 10-03-2017 RG49_RS04690 39d3c02d553720ba2f5014dc34a7ec45 203 SUPERFAMILY SSF53955 37 194 2.11E-26 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS08790 52762d32c4bba225824c9d1a93b2d1b3 397 SUPERFAMILY SSF111369 52 300 1.57E-89 T 10-03-2017 RG49_RS08790 52762d32c4bba225824c9d1a93b2d1b3 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 375 1.8E-86 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS08790 52762d32c4bba225824c9d1a93b2d1b3 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 293 2.1E-13 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS08790 52762d32c4bba225824c9d1a93b2d1b3 397 Pfam PF00529 HlyD membrane-fusion protein of T1SS 38 360 4.0E-14 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS08790 52762d32c4bba225824c9d1a93b2d1b3 397 Gene3D G3DSA:2.40.50.100 65 98 1.3E-25 T 10-03-2017 RG49_RS08790 52762d32c4bba225824c9d1a93b2d1b3 397 Gene3D G3DSA:2.40.50.100 173 208 1.3E-25 T 10-03-2017 RG49_RS15650 2eae0f3ac2fab7069bacd829c31a55d7 188 SUPERFAMILY SSF52218 7 178 1.47E-43 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS15650 2eae0f3ac2fab7069bacd829c31a55d7 188 Pfam PF03358 NADPH-dependent FMN reductase 6 148 1.1E-38 T 10-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 RG49_RS15650 2eae0f3ac2fab7069bacd829c31a55d7 188 Gene3D G3DSA:3.40.50.360 2 187 2.9E-50 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS08270 1b2ce3fc66d1f5314bd2551fc7556b58 82 ProDom PD027061 YBDJ MEMBRANE TRANSMEMBRANE INNER RAMA 3'REGION ECS0618 1 82 2.0E-28 T 10-03-2017 IPR010590 Protein of unknown function DUF1158 RG49_RS08270 1b2ce3fc66d1f5314bd2551fc7556b58 82 Pfam PF06643 Protein of unknown function (DUF1158) 1 79 1.6E-44 T 10-03-2017 IPR010590 Protein of unknown function DUF1158 RG49_RS04255 23c2bb606301d96867c8384cd09f367b 293 SMART SM00481 10 77 1.9E-18 T 10-03-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 RG49_RS04255 23c2bb606301d96867c8384cd09f367b 293 Gene3D G3DSA:3.20.20.140 10 95 1.2E-41 T 10-03-2017 RG49_RS04255 23c2bb606301d96867c8384cd09f367b 293 Gene3D G3DSA:3.20.20.140 164 268 1.2E-41 T 10-03-2017 RG49_RS04255 23c2bb606301d96867c8384cd09f367b 293 Pfam PF02811 PHP domain 11 115 1.2E-6 T 10-03-2017 IPR004013 PHP domain GO:0003824 RG49_RS04255 23c2bb606301d96867c8384cd09f367b 293 SUPERFAMILY SSF89550 172 285 3.53E-52 T 10-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 RG49_RS04255 23c2bb606301d96867c8384cd09f367b 293 SUPERFAMILY SSF89550 9 90 3.53E-52 T 10-03-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 RG49_RS22255 27f16372a240005d2e2e205f11d1073e 282 SUPERFAMILY SSF53697 100 261 9.46E-31 T 10-03-2017 RG49_RS22255 27f16372a240005d2e2e205f11d1073e 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 2.3E-29 T 10-03-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 RG49_RS22255 27f16372a240005d2e2e205f11d1073e 282 SUPERFAMILY SSF46689 1 77 3.4E-19 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS22255 27f16372a240005d2e2e205f11d1073e 282 Gene3D G3DSA:1.10.10.10 1 77 3.2E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22255 27f16372a240005d2e2e205f11d1073e 282 Gene3D G3DSA:3.40.50.10490 103 262 2.1E-31 T 10-03-2017 RG49_RS22255 27f16372a240005d2e2e205f11d1073e 282 Pfam PF01380 SIS domain 128 258 9.9E-32 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS19895 5906ab6a487a988f797855890557a11d 254 Gene3D G3DSA:1.10.10.10 2 74 8.5E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19895 5906ab6a487a988f797855890557a11d 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.6E-7 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS19895 5906ab6a487a988f797855890557a11d 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.6E-7 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS19895 5906ab6a487a988f797855890557a11d 254 SMART SM00345 12 71 5.2E-10 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS19895 5906ab6a487a988f797855890557a11d 254 SUPERFAMILY SSF46785 4 75 6.67E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19895 5906ab6a487a988f797855890557a11d 254 SUPERFAMILY SSF48008 93 233 3.66E-24 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS19895 5906ab6a487a988f797855890557a11d 254 Pfam PF07729 FCD domain 96 226 3.2E-22 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS19895 5906ab6a487a988f797855890557a11d 254 Gene3D G3DSA:1.20.120.530 91 235 1.1E-27 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS19895 5906ab6a487a988f797855890557a11d 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 69 1.3E-13 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS19895 5906ab6a487a988f797855890557a11d 254 SMART SM00895 96 227 1.3E-20 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 Gene3D G3DSA:3.40.50.20 2 129 1.2E-55 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 296 1.0E-79 T 10-03-2017 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 2 120 2.0E-46 T 10-03-2017 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 Gene3D G3DSA:3.30.470.20 192 297 6.8E-50 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 TIGRFAM TIGR01380 glut_syn: glutathione synthase 2 311 4.0E-140 T 10-03-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 SUPERFAMILY SSF56059 123 312 4.86E-60 T 10-03-2017 RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 182.217 T 10-03-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 SUPERFAMILY SSF52440 2 122 3.45E-46 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS20150 b378c0526677f8dce7b53174eed7d879 316 Gene3D G3DSA:3.30.1490.20 137 191 3.6E-32 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.5E-25 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.9E-11 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.9E-11 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 Gene3D G3DSA:1.20.120.530 97 238 5.3E-18 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 SUPERFAMILY SSF46785 6 76 4.2E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 Gene3D G3DSA:1.10.10.10 7 76 2.4E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 SUPERFAMILY SSF48008 95 234 3.4E-20 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 Pfam PF07729 FCD domain 99 226 2.4E-17 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 SMART SM00345 15 74 3.0E-29 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS11295 46a9878e5f5f0a1f25c26a908baa14ab 254 SMART SM00895 99 227 9.2E-17 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS20435 f57c9a3f968e1c498a2475a37bf5b8d9 236 Gene3D G3DSA:3.40.30.10 98 231 1.1E-53 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS20435 f57c9a3f968e1c498a2475a37bf5b8d9 236 Pfam PF13098 Thioredoxin-like domain 104 226 5.5E-30 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS20435 f57c9a3f968e1c498a2475a37bf5b8d9 236 Pfam PF10411 Disulfide bond isomerase protein N-terminus 26 75 6.5E-15 T 10-03-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal RG49_RS20435 f57c9a3f968e1c498a2475a37bf5b8d9 236 Gene3D G3DSA:3.10.450.70 21 81 2.2E-27 T 10-03-2017 IPR009094 Disulphide bond isomerase, DsbC, N-terminal RG49_RS20435 f57c9a3f968e1c498a2475a37bf5b8d9 236 SUPERFAMILY SSF54423 22 80 1.44E-18 T 10-03-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal RG49_RS20435 f57c9a3f968e1c498a2475a37bf5b8d9 236 ProSitePatterns PS00194 Thioredoxin family active site. 110 128 - T 10-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 RG49_RS20435 f57c9a3f968e1c498a2475a37bf5b8d9 236 SUPERFAMILY SSF52833 85 230 1.7E-44 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS09055 726e62e250bbd136faca4fd18d794103 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 31.65 T 10-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS09055 726e62e250bbd136faca4fd18d794103 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 3.3E-60 T 10-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS09055 726e62e250bbd136faca4fd18d794103 156 SUPERFAMILY SSF52121 4 154 7.85E-59 T 10-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS09055 726e62e250bbd136faca4fd18d794103 156 Gene3D G3DSA:3.40.50.960 2 152 3.0E-63 T 10-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS09055 726e62e250bbd136faca4fd18d794103 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 2.1E-54 T 10-03-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 Pfam PF02108 Flagellar assembly protein FliH 96 219 1.2E-40 T 10-03-2017 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 133 155 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 184 200 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 53 75 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 76 94 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 5 24 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 156 183 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 201 226 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 115 132 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS00210 691a3d59b279bebb2ddd108b16cca226 228 PRINTS PR01003 Flagellar assembly protein FliH signature 95 114 1.9E-119 T 10-03-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Pfam PF02727 Copper amine oxidase, N2 domain 124 209 2.3E-29 T 10-03-2017 IPR015800 Copper amine oxidase, N2-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Gene3D G3DSA:3.30.457.10 36 113 2.2E-24 T 10-03-2017 IPR012854 Copper amine oxidase-like, N-terminal RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 SUPERFAMILY SSF49998 333 751 3.66E-143 T 10-03-2017 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 485 498 - T 10-03-2017 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Gene3D G3DSA:3.10.450.40 218 308 1.2E-36 T 10-03-2017 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 SUPERFAMILY SSF55383 36 115 2.09E-19 T 10-03-2017 IPR012854 Copper amine oxidase-like, N-terminal RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 ProSitePatterns PS01165 Copper amine oxidase copper-binding site signature. 714 727 - T 10-03-2017 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Gene3D G3DSA:3.10.450.40 117 215 4.7E-31 T 10-03-2017 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Pfam PF07833 Copper amine oxidase N-terminal domain 37 110 1.3E-10 T 10-03-2017 IPR012854 Copper amine oxidase-like, N-terminal RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Gene3D G3DSA:2.70.98.20 309 751 2.6E-144 T 10-03-2017 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Pfam PF02728 Copper amine oxidase, N3 domain 216 317 7.8E-28 T 10-03-2017 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 Pfam PF01179 Copper amine oxidase, enzyme domain 337 750 4.9E-127 T 10-03-2017 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 SUPERFAMILY SSF54416 122 214 4.74E-24 T 10-03-2017 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 RG49_RS03465 d63f3c8eb62c129a1cba353e46276d06 757 SUPERFAMILY SSF54416 216 324 1.25E-28 T 10-03-2017 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 SUPERFAMILY SSF47413 2 61 2.04E-18 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 Gene3D G3DSA:3.40.50.2300 177 311 1.3E-45 T 10-03-2017 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 10-03-2017 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 SMART SM00354 3 73 2.3E-34 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 Pfam PF13377 Periplasmic binding protein-like domain 171 329 8.3E-33 T 10-03-2017 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 1.8E-22 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 3.3E-5 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 3.3E-5 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 Gene3D G3DSA:1.10.260.40 4 64 3.8E-25 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 Gene3D G3DSA:3.40.50.2300 65 176 6.2E-42 T 10-03-2017 RG49_RS09405 1424a24444085ca914df6d6e0a03d9a4 360 SUPERFAMILY SSF53822 61 326 1.06E-54 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS02400 7a28d3e8f9bf133ddaeb6eb985551573 707 Gene3D G3DSA:3.90.226.10 50 233 5.2E-46 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS02400 7a28d3e8f9bf133ddaeb6eb985551573 707 Pfam PF00574 Clp protease 63 223 4.7E-37 T 10-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA RG49_RS02400 7a28d3e8f9bf133ddaeb6eb985551573 707 Pfam PF10124 Mu-like prophage major head subunit gpT 566 639 1.1E-4 T 10-03-2017 IPR018774 Bacteriophage Mu, GpT RG49_RS02400 7a28d3e8f9bf133ddaeb6eb985551573 707 SUPERFAMILY SSF52096 49 230 9.45E-49 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS02400 7a28d3e8f9bf133ddaeb6eb985551573 707 PRINTS PR00127 Clp protease catalytic subunit P signature 94 114 1.4E-8 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS02400 7a28d3e8f9bf133ddaeb6eb985551573 707 PRINTS PR00127 Clp protease catalytic subunit P signature 125 142 1.4E-8 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS02400 7a28d3e8f9bf133ddaeb6eb985551573 707 PRINTS PR00127 Clp protease catalytic subunit P signature 201 220 1.4E-8 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 SUPERFAMILY SSF53850 98 314 2.17E-27 T 10-03-2017 RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 Hamap MF_01607 HTH-type transcriptional regulator YidZ [yidZ]. 1 319 73.519 T 10-03-2017 IPR023746 Transcription regulator HTH, YidZ GO:0003700|GO:0006355 RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 Gene3D G3DSA:3.40.190.10 98 181 4.6E-16 T 10-03-2017 RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 Gene3D G3DSA:3.40.190.10 290 318 4.6E-16 T 10-03-2017 RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 Pfam PF03466 LysR substrate binding domain 106 313 3.5E-16 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 SUPERFAMILY SSF46785 7 81 3.77E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 Gene3D G3DSA:3.40.190.10 182 279 5.9E-28 T 10-03-2017 RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 1.8E-13 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15660 23e471c3c44d1fb21b6d72a9b41c0317 319 Gene3D G3DSA:1.10.10.10 2 87 2.6E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12560 c58037d5f6c70641273ef019840218c6 636 Gene3D G3DSA:1.10.443.10 422 589 1.2E-16 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS12560 c58037d5f6c70641273ef019840218c6 636 SUPERFAMILY SSF56349 343 588 2.35E-31 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS12560 c58037d5f6c70641273ef019840218c6 636 SUPERFAMILY SSF56349 257 313 2.35E-31 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS12560 c58037d5f6c70641273ef019840218c6 636 Pfam PF00589 Phage integrase family 438 582 2.4E-10 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS12520 acb472126b6ee984dcdabf55abf4f8c7 716 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 406 709 1.1E-69 T 10-03-2017 IPR022625 Type-1 restriction enzyme R protein, C-terminal RG49_RS12520 acb472126b6ee984dcdabf55abf4f8c7 716 ProDom PD047574 TYPE I RESTRICTION HYDROLASE DEOXYRIBONUCLEASE SITE-SPECIFIC HSDR ENZYME SYSTEM ENDONUCLEASE 515 550 5.0E-7 T 10-03-2017 RG49_RS12520 acb472126b6ee984dcdabf55abf4f8c7 716 SUPERFAMILY SSF52540 8 118 2.19E-15 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12520 acb472126b6ee984dcdabf55abf4f8c7 716 Gene3D G3DSA:3.40.50.300 10 121 6.4E-14 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12520 acb472126b6ee984dcdabf55abf4f8c7 716 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 4 403 2.0E-136 T 10-03-2017 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 RG49_RS12520 acb472126b6ee984dcdabf55abf4f8c7 716 Pfam PF04851 Type III restriction enzyme, res subunit 9 117 6.5E-23 T 10-03-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 RG49_RS18700 8e9fca70277051eb4b503c63b7d1e731 92 Gene3D G3DSA:1.10.260.40 6 72 5.0E-38 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS18700 8e9fca70277051eb4b503c63b7d1e731 92 Pfam PF13693 Winged helix-turn-helix DNA-binding 7 81 1.4E-35 T 10-03-2017 RG49_RS18700 8e9fca70277051eb4b503c63b7d1e731 92 SUPERFAMILY SSF47413 3 72 5.06E-29 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02290 a022d29449528b2a0288cfe7ef882cb0 70 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 43 5.5E-14 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS02290 a022d29449528b2a0288cfe7ef882cb0 70 PRINTS PR00281 Hok/Gef cell toxic protein family signature 45 67 5.5E-14 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS02290 a022d29449528b2a0288cfe7ef882cb0 70 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 30 49 - T 10-03-2017 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 RG49_RS02290 a022d29449528b2a0288cfe7ef882cb0 70 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 31 68 3.0E-5 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS02290 a022d29449528b2a0288cfe7ef882cb0 70 Pfam PF01848 Hok/gef family 25 66 3.9E-19 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 SUPERFAMILY SSF50692 631 774 4.97E-38 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 Pfam PF01568 Molydopterin dinucleotide binding domain 637 740 4.1E-24 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 13 775 0.0 T 10-03-2017 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 675 702 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 SUPERFAMILY SSF53706 14 633 1.27E-161 T 10-03-2017 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 Gene3D G3DSA:3.40.228.10 155 363 9.4E-61 T 10-03-2017 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 459 476 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 Gene3D G3DSA:3.40.50.740 364 460 2.2E-45 T 10-03-2017 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 Gene3D G3DSA:3.40.50.740 48 150 2.2E-45 T 10-03-2017 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 Gene3D G3DSA:2.40.40.20 612 770 5.1E-54 T 10-03-2017 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 Gene3D G3DSA:3.90.55.10 461 567 1.3E-35 T 10-03-2017 RG49_RS16730 0d8b152d8892464f6c3daf1533d58782 777 Pfam PF00384 Molybdopterin oxidoreductase 56 517 8.5E-113 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 SUPERFAMILY SSF57825 101 151 1.7E-15 T 10-03-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 SUPERFAMILY SSF54893 2 100 8.24E-36 T 10-03-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 152 1.7E-73 T 10-03-2017 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 32.847 T 10-03-2017 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 9.0E-48 T 10-03-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 149 1.2E-18 T 10-03-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 Gene3D G3DSA:2.30.30.20 101 152 7.0E-24 T 10-03-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 96 1.1E-30 T 10-03-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal RG49_RS12670 3b4798139750e07d544a7cf29d8b335c 153 Gene3D G3DSA:3.30.70.140 2 98 6.4E-38 T 10-03-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 107 447 1.1E-143 T 10-03-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 SUPERFAMILY SSF56322 4 452 4.71E-147 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 Gene3D G3DSA:3.60.120.10 11 452 1.1E-153 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 Pfam PF04715 Anthranilate synthase component I, N terminal region 22 153 1.1E-28 T 10-03-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 Pfam PF00425 chorismate binding enzyme 190 443 7.0E-92 T 10-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 PRINTS PR00095 Anthranilate synthase component I signature 305 318 1.3E-18 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 PRINTS PR00095 Anthranilate synthase component I signature 291 304 1.3E-18 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 PRINTS PR00095 Anthranilate synthase component I signature 385 399 1.3E-18 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS00915 4b9e0cd37f8a6f4dfd23063e16af5c80 453 PRINTS PR00095 Anthranilate synthase component I signature 400 414 1.3E-18 T 10-03-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 Gene3D G3DSA:3.40.190.10 178 253 7.7E-20 T 10-03-2017 RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 SUPERFAMILY SSF53850 87 291 1.69E-41 T 10-03-2017 RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.0E-16 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 Gene3D G3DSA:1.10.10.10 1 87 1.0E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 Pfam PF03466 LysR substrate binding domain 86 288 1.6E-43 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.9E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.9E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.9E-6 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 SUPERFAMILY SSF46785 2 109 7.07E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15050 67d8c6fb034ee63a05d25161df201b8a 317 Gene3D G3DSA:3.40.190.10 90 177 1.2E-14 T 10-03-2017 RG49_RS04105 4cfe0c68e4c5d78a423eae94dc053b4f 117 Gene3D G3DSA:3.40.960.10 70 111 7.1E-5 T 10-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 RG49_RS04105 4cfe0c68e4c5d78a423eae94dc053b4f 117 Pfam PF04480 Protein of unknown function (DUF559) 4 111 1.2E-49 T 10-03-2017 IPR007569 Domain of unknown function DUF559 RG49_RS04105 4cfe0c68e4c5d78a423eae94dc053b4f 117 SUPERFAMILY SSF52980 7 113 2.63E-26 T 10-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 Pfam PF00072 Response regulator receiver domain 9 120 8.2E-31 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 SMART SM00448 7 120 3.8E-37 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 1.4E-22 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 Gene3D G3DSA:1.10.10.10 155 214 1.2E-28 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 SMART SM00421 153 210 1.0E-25 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 SUPERFAMILY SSF52172 6 135 1.42E-36 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 SUPERFAMILY SSF46894 146 213 1.36E-20 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 Gene3D G3DSA:3.40.50.2300 5 154 5.4E-41 T 10-03-2017 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.1E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.1E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS04515 8f80a9379e52023221a7cf06252eb4cc 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.1E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.685 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 Gene3D G3DSA:3.30.70.141 1 140 1.0E-58 T 10-03-2017 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 10-03-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 Pfam PF00334 Nucleoside diphosphate kinase 4 137 5.5E-54 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.1E-40 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.1E-40 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.1E-40 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.1E-40 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.1E-40 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 SUPERFAMILY SSF54919 1 141 2.1E-58 T 10-03-2017 RG49_RS22480 54fef7552ef7599096562610b89c5009 143 SMART SM00562 3 140 3.0E-86 T 10-03-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS18460 1dcea8291547c6a54a40baf28d6dee89 375 Gene3D G3DSA:3.40.50.300 37 184 3.8E-21 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18460 1dcea8291547c6a54a40baf28d6dee89 375 Hamap MF_01919 Cell division protein ZapE [zapE]. 4 374 53.842 T 10-03-2017 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 RG49_RS18460 1dcea8291547c6a54a40baf28d6dee89 375 Pfam PF03969 AFG1-like ATPase 4 371 8.6E-171 T 10-03-2017 IPR005654 ATPase, AFG1-like GO:0005524 RG49_RS18460 1dcea8291547c6a54a40baf28d6dee89 375 SUPERFAMILY SSF52540 69 208 2.33E-13 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05175 10c00c0561de7dcf4030f0d748031d11 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 10-03-2017 IPR006162 Phosphopantetheine attachment site RG49_RS05175 10c00c0561de7dcf4030f0d748031d11 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.327 T 10-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05175 10c00c0561de7dcf4030f0d748031d11 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 7.2E-17 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS05175 10c00c0561de7dcf4030f0d748031d11 78 Gene3D G3DSA:1.10.1200.10 3 77 8.4E-37 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS05175 10c00c0561de7dcf4030f0d748031d11 78 SUPERFAMILY SSF47336 2 77 1.44E-24 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS05175 10c00c0561de7dcf4030f0d748031d11 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 1.1E-38 T 10-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05175 10c00c0561de7dcf4030f0d748031d11 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 4.0E-4 T 10-03-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS11440 049383c87ab3f6e97f9a4884f97c116f 121 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 36 118 1.1E-28 T 10-03-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 RG49_RS11440 049383c87ab3f6e97f9a4884f97c116f 121 Hamap MF_00910 Cell division protein FtsL [ftsL]. 35 118 16.85 T 10-03-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 RG49_RS11440 049383c87ab3f6e97f9a4884f97c116f 121 Pfam PF04999 Cell division protein FtsL 25 119 2.3E-35 T 10-03-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 RG49_RS15025 bab51ab7b460e5a9233b143e233ded2e 470 Pfam PF02646 RmuC family 131 427 2.1E-107 T 10-03-2017 IPR003798 DNA recombination RmuC RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 SUPERFAMILY SSF46689 147 187 5.73E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 Gene3D G3DSA:1.10.10.60 146 189 1.1E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 SUPERFAMILY SSF53041 3 144 2.62E-37 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 ProSitePatterns PS00398 Site-specific recombinases signature 2. 63 75 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 SMART SM00857 4 145 4.2E-49 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 Gene3D G3DSA:3.40.50.1390 3 127 1.3E-35 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 Pfam PF00239 Resolvase, N terminal domain 5 144 3.9E-36 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS02485 34e29f4f7976980d5e73dac15cf967bc 196 Pfam PF02796 Helix-turn-helix domain of resolvase 147 190 6.0E-11 T 10-03-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 SUPERFAMILY SSF51395 205 257 2.43E-12 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 SUPERFAMILY SSF51395 287 405 2.43E-12 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 SUPERFAMILY SSF51395 44 140 2.43E-12 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:3.20.20.70 154 260 9.0E-6 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:3.20.20.70 43 88 9.0E-6 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:3.20.20.70 293 368 9.0E-6 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:1.10.1060.10 887 952 7.8E-12 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:1.10.1060.10 418 549 5.4E-25 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:3.50.50.60 634 775 2.6E-37 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:3.50.50.60 776 851 1.6E-9 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 SUPERFAMILY SSF51971 551 786 7.65E-48 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 TIGRFAM TIGR03315 Se_ygfK: putative selenate reductase, YgfK subunit 2 1027 0.0 T 10-03-2017 IPR017701 Putative selenate reductase YgfK RG49_RS20515 affccc9169b0550a7326170650a89211 1032 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 938 949 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS20515 affccc9169b0550a7326170650a89211 1032 PRINTS PR00419 Adrenodoxin reductase family signature 575 588 3.3E-16 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 PRINTS PR00419 Adrenodoxin reductase family signature 552 574 3.3E-16 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 PRINTS PR00419 Adrenodoxin reductase family signature 681 695 3.3E-16 T 10-03-2017 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 SUPERFAMILY SSF46548 396 561 3.66E-20 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Gene3D G3DSA:3.50.50.60 550 628 1.9E-14 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 SUPERFAMILY SSF46548 872 962 1.52E-9 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 552 840 2.6E-46 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS20515 affccc9169b0550a7326170650a89211 1032 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 453 532 6.7E-16 T 10-03-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 RG49_RS21380 fe2d49c088577750c4b7c90374c139bd 212 SUPERFAMILY SSF53639 7 211 8.63E-60 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS21380 fe2d49c088577750c4b7c90374c139bd 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 14 190 7.9E-45 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS21380 fe2d49c088577750c4b7c90374c139bd 212 Gene3D G3DSA:3.40.225.10 8 211 1.2E-65 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS21380 fe2d49c088577750c4b7c90374c139bd 212 SMART SM01007 13 192 6.0E-56 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS23295 8155697a9afcb04958b3261f25646398 381 Gene3D G3DSA:3.40.50.10540 6 220 6.5E-98 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS23295 8155697a9afcb04958b3261f25646398 381 Gene3D G3DSA:3.40.50.10540 309 378 6.5E-98 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS23295 8155697a9afcb04958b3261f25646398 381 SUPERFAMILY SSF89796 8 378 1.31E-122 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS23295 8155697a9afcb04958b3261f25646398 381 Gene3D G3DSA:3.30.1540.10 226 308 2.9E-26 T 10-03-2017 RG49_RS23295 8155697a9afcb04958b3261f25646398 381 Pfam PF02515 CoA-transferase family III 11 361 2.3E-114 T 10-03-2017 IPR003673 CoA-transferase family III GO:0003824 RG49_RS16890 591b84a30cf87f265aca74e16f774d89 498 Pfam PF00675 Insulinase (Peptidase family M16) 46 164 7.7E-6 T 10-03-2017 IPR011765 Peptidase M16, N-terminal RG49_RS16890 591b84a30cf87f265aca74e16f774d89 498 Pfam PF05193 Peptidase M16 inactive domain 201 377 1.9E-18 T 10-03-2017 IPR007863 Peptidase M16, C-terminal RG49_RS16890 591b84a30cf87f265aca74e16f774d89 498 SUPERFAMILY SSF63411 29 239 2.79E-24 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS16890 591b84a30cf87f265aca74e16f774d89 498 Gene3D G3DSA:3.30.830.10 25 252 9.9E-22 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS16890 591b84a30cf87f265aca74e16f774d89 498 SUPERFAMILY SSF63411 296 452 4.71E-6 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS22725 e465515bd56e7c2862b9ad8e0ac8d7eb 216 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 13 197 3.0E-87 T 10-03-2017 RG49_RS22725 e465515bd56e7c2862b9ad8e0ac8d7eb 216 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 128 211 2.2E-11 T 10-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 Pfam PF03466 LysR substrate binding domain 90 294 5.6E-37 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 Gene3D G3DSA:1.10.10.10 6 90 1.3E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 Gene3D G3DSA:3.40.190.10 179 263 7.4E-14 T 10-03-2017 RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.0E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 SUPERFAMILY SSF53850 92 294 2.53E-36 T 10-03-2017 RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 Gene3D G3DSA:3.40.190.10 94 178 4.3E-16 T 10-03-2017 RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 SUPERFAMILY SSF46785 6 90 1.7E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.5E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.5E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03895 35e42455de2c2a1e98cd2244438c9b2e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.5E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 Pfam PF00994 Probable molybdopterin binding domain 14 156 1.4E-32 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 PIRSF PIRSF006443 1 166 1.6E-62 T 10-03-2017 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 153 1.9E-39 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 7 169 2.7E-83 T 10-03-2017 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 Gene3D G3DSA:3.40.980.10 8 169 4.9E-51 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 SMART SM00852 14 158 3.3E-30 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 10-03-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 RG49_RS07120 1d192ad9a2cf2749c9862f362feb18bc 170 SUPERFAMILY SSF53218 7 168 1.3E-46 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82693 146 191 1.7E-21 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82693 277 333 1.7E-21 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82714 192 275 8.24E-17 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Pfam PF00873 AcrB/AcrD/AcrF family 13 1022 0.0 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Hamap MF_01423 Multidrug resistance protein MdtB [mdtB]. 1 1037 33.68 T 10-03-2017 IPR022831 Multidrug resistance protein MdtB RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82866 800 1028 1.57E-45 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Gene3D G3DSA:3.30.2090.10 719 804 1.1E-17 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82714 719 800 7.59E-17 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82693 565 661 1.55E-17 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82693 49 138 1.65E-23 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 SUPERFAMILY SSF82866 299 498 6.93E-45 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Gene3D G3DSA:3.30.2090.10 192 275 2.9E-18 T 10-03-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Gene3D G3DSA:3.30.70.1430 49 151 4.9E-30 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Gene3D G3DSA:1.20.1640.10 294 509 9.3E-55 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Gene3D G3DSA:1.10.3850.10 807 1024 3.6E-56 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 Gene3D G3DSA:3.30.70.1430 568 658 9.2E-13 T 10-03-2017 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 47 65 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 19 43 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24800 1a9048d9ee894802107907cbc474db45 1040 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 1.5E-80 T 10-03-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 SUPERFAMILY SSF53706 2 407 7.46E-146 T 10-03-2017 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 Pfam PF00384 Molybdopterin oxidoreductase 1 331 9.6E-89 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 459 486 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 Gene3D G3DSA:3.40.228.10 15 207 6.7E-79 T 10-03-2017 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 Gene3D G3DSA:3.40.50.740 1 14 3.8E-48 T 10-03-2017 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 Gene3D G3DSA:3.40.50.740 222 353 3.8E-48 T 10-03-2017 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 Gene3D G3DSA:1.20.5.460 533 559 3.5E-19 T 10-03-2017 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 1 529 5.9E-255 T 10-03-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 SUPERFAMILY SSF50692 409 547 5.65E-41 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 Gene3D G3DSA:2.40.40.20 369 532 2.8E-43 T 10-03-2017 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 Pfam PF01568 Molydopterin dinucleotide binding domain 420 526 2.1E-26 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS13600 ec323668f3c0f056e08b0296b3c6b6ad 559 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 277 294 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS11555 6b2172851e3c9c739fb80bec14132c3f 566 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 291 501 2.7E-36 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS11555 6b2172851e3c9c739fb80bec14132c3f 566 Gene3D G3DSA:3.30.420.40 285 545 9.4E-43 T 10-03-2017 RG49_RS11555 6b2172851e3c9c739fb80bec14132c3f 566 SUPERFAMILY SSF53067 285 545 8.2E-42 T 10-03-2017 RG49_RS11555 6b2172851e3c9c739fb80bec14132c3f 566 Hamap MF_00520 Ribulokinase [araB]. 1 558 60.073 T 10-03-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 RG49_RS11555 6b2172851e3c9c739fb80bec14132c3f 566 SUPERFAMILY SSF53067 5 284 2.98E-22 T 10-03-2017 RG49_RS11555 6b2172851e3c9c739fb80bec14132c3f 566 Gene3D G3DSA:3.30.420.40 3 282 6.8E-29 T 10-03-2017 RG49_RS11555 6b2172851e3c9c739fb80bec14132c3f 566 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 2 552 4.3E-283 T 10-03-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 Gene3D G3DSA:3.40.50.1000 1 74 1.3E-48 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 Gene3D G3DSA:3.40.50.1000 179 264 1.3E-48 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 4.1E-66 T 10-03-2017 IPR000150 Cof protein GO:0016787 RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 232 9.5E-22 T 10-03-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 SUPERFAMILY SSF56784 1 262 1.06E-63 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 ProSitePatterns PS01229 Hypothetical cof family signature 2. 213 235 - T 10-03-2017 RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 1.9E-53 T 10-03-2017 IPR023214 HAD-like domain RG49_RS06895 3b2c55884d5bf82f5e0399197e3ae062 271 Gene3D G3DSA:3.30.1240.10 84 178 1.1E-33 T 10-03-2017 RG49_RS05195 4c0da28cfac3276414ddb92eade91f86 356 SUPERFAMILY SSF53659 4 340 1.03E-103 T 10-03-2017 RG49_RS05195 4c0da28cfac3276414ddb92eade91f86 356 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 345 142.289 T 10-03-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 RG49_RS05195 4c0da28cfac3276414ddb92eade91f86 356 Pfam PF02504 Fatty acid synthesis protein 5 331 7.3E-130 T 10-03-2017 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 RG49_RS05195 4c0da28cfac3276414ddb92eade91f86 356 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 345 8.9E-149 T 10-03-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 RG49_RS05195 4c0da28cfac3276414ddb92eade91f86 356 PIRSF PIRSF002465 2 343 2.3E-128 T 10-03-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 RG49_RS05195 4c0da28cfac3276414ddb92eade91f86 356 Gene3D G3DSA:3.40.718.10 3 339 6.2E-136 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS23635 f90d60219db6a32804d897d57c9f691e 405 Gene3D G3DSA:3.40.640.10 51 279 2.3E-68 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS23635 f90d60219db6a32804d897d57c9f691e 405 SUPERFAMILY SSF53383 7 401 4.17E-94 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS23635 f90d60219db6a32804d897d57c9f691e 405 Pfam PF00155 Aminotransferase class I and II 58 387 8.6E-47 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS23635 f90d60219db6a32804d897d57c9f691e 405 Gene3D G3DSA:3.90.1150.10 280 403 9.3E-38 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS01095 acca6325d1d2cdeab1f6106e3f4038c3 137 Pfam PF01641 SelR domain 9 127 1.2E-54 T 10-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 RG49_RS01095 acca6325d1d2cdeab1f6106e3f4038c3 137 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 3 129 38.685 T 10-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 RG49_RS01095 acca6325d1d2cdeab1f6106e3f4038c3 137 SUPERFAMILY SSF51316 5 133 1.99E-59 T 10-03-2017 IPR011057 Mss4-like RG49_RS01095 acca6325d1d2cdeab1f6106e3f4038c3 137 Gene3D G3DSA:2.170.150.20 4 133 9.5E-62 T 10-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 RG49_RS01095 acca6325d1d2cdeab1f6106e3f4038c3 137 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 4 136 3.3E-68 T 10-03-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 SUPERFAMILY SSF51658 4 438 2.83E-172 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 Hamap MF_00455 Xylose isomerase [xylA]. 11 437 54.049 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 133 153 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 229 253 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 156 175 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 180 201 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 300 311 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 271 298 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 92 114 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 333 344 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 PRINTS PR00688 Xylose isomerase signature 207 226 9.2E-86 T 10-03-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 Gene3D G3DSA:3.20.20.150 3 439 2.4E-212 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS16650 547b8ae97de5f7bdf88ee5887850c66e 440 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 4 437 8.4E-221 T 10-03-2017 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 RG49_RS16335 58b0b0c0ea5f78595a91b9c5de63e9d7 427 Pfam PF01551 Peptidase family M23 328 421 5.6E-26 T 10-03-2017 IPR016047 Peptidase M23 RG49_RS16335 58b0b0c0ea5f78595a91b9c5de63e9d7 427 SUPERFAMILY SSF51261 226 425 3.45E-47 T 10-03-2017 IPR011055 Duplicated hybrid motif RG49_RS16335 58b0b0c0ea5f78595a91b9c5de63e9d7 427 Gene3D G3DSA:2.70.70.10 288 426 5.1E-36 T 10-03-2017 RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 SUPERFAMILY SSF46785 20 90 2.03E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 Pfam PF07702 UTRA domain 108 242 2.1E-35 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 87 4.8E-16 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 SUPERFAMILY SSF64288 75 246 4.71E-40 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 SMART SM00866 107 243 3.7E-32 T 10-03-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 8.6E-10 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 8.6E-10 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 SMART SM00345 28 87 2.4E-15 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 Gene3D G3DSA:1.10.10.10 20 89 3.4E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24680 e7651cd274047e1c6cfe7a7008bcbc94 248 Gene3D G3DSA:3.40.1410.10 93 247 2.9E-44 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 882 889 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Gene3D G3DSA:1.10.2060.10 142 260 3.5E-55 T 10-03-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 610 1112 5.2E-263 T 10-03-2017 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 SUPERFAMILY SSF47598 3 45 3.11E-10 T 10-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 148 259 3.1E-46 T 10-03-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 910 921 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Pfam PF01619 Proline dehydrogenase 270 569 6.6E-99 T 10-03-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 SUPERFAMILY SSF81935 88 261 5.1E-67 T 10-03-2017 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 PIRSF PIRSF000197 74 1320 0.0 T 10-03-2017 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Gene3D G3DSA:3.20.20.220 261 616 2.9E-122 T 10-03-2017 IPR029041 FAD-linked oxidoreductase-like RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Gene3D G3DSA:1.20.5.550 87 138 3.9E-26 T 10-03-2017 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 SUPERFAMILY SSF53720 657 1110 7.33E-125 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Gene3D G3DSA:3.40.309.10 898 1090 1.5E-44 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 SUPERFAMILY SSF51730 262 618 9.42E-124 T 10-03-2017 IPR029041 FAD-linked oxidoreductase-like RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Pfam PF00171 Aldehyde dehydrogenase family 659 1105 1.0E-112 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS05625 cb099d7af9dc78d3084ecfdafd86c2f0 1320 Gene3D G3DSA:3.40.605.10 655 897 1.4E-67 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS06440 70563109a451dc689384814cec661e65 242 SMART SM00382 27 218 5.0E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06440 70563109a451dc689384814cec661e65 242 Gene3D G3DSA:3.40.50.300 3 237 5.6E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06440 70563109a451dc689384814cec661e65 242 SUPERFAMILY SSF52540 3 232 1.14E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06440 70563109a451dc689384814cec661e65 242 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06440 70563109a451dc689384814cec661e65 242 PIRSF PIRSF039085 1 242 8.2E-85 T 10-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 RG49_RS06440 70563109a451dc689384814cec661e65 242 Pfam PF00005 ABC transporter 20 170 5.0E-35 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS22590 f4bca165880b2f512dbe898970fc8185 927 SUPERFAMILY SSF53335 481 600 1.54E-45 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS22590 f4bca165880b2f512dbe898970fc8185 927 SUPERFAMILY SSF53335 168 448 1.54E-45 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS22590 f4bca165880b2f512dbe898970fc8185 927 Gene3D G3DSA:3.40.50.150 343 513 1.0E-14 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS24860 e7b76eb58f4406287f72f3e601714f80 617 Pfam PF05170 AsmA family 227 511 1.9E-23 T 10-03-2017 IPR007844 AsmA RG49_RS03885 18783cf6b9c22b11ef751edeeb77a36d 537 PIRSF PIRSF002741 2 537 1.8E-112 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS03885 18783cf6b9c22b11ef751edeeb77a36d 537 Gene3D G3DSA:3.10.105.10 291 505 1.1E-64 T 10-03-2017 RG49_RS03885 18783cf6b9c22b11ef751edeeb77a36d 537 Gene3D G3DSA:3.90.76.10 44 216 1.7E-48 T 10-03-2017 RG49_RS03885 18783cf6b9c22b11ef751edeeb77a36d 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 453 6.3E-88 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS03885 18783cf6b9c22b11ef751edeeb77a36d 537 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 83 104 - T 10-03-2017 IPR023765 Solute-binding protein family 5, conserved site RG49_RS03885 18783cf6b9c22b11ef751edeeb77a36d 537 SUPERFAMILY SSF53850 32 528 2.1E-140 T 10-03-2017 RG49_RS02980 a41335fe081d940f906c40544689ec2d 96 Pfam PF00267 Gram-negative porin 27 91 4.1E-24 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS02980 a41335fe081d940f906c40544689ec2d 96 Gene3D G3DSA:2.40.160.10 22 91 1.2E-18 T 10-03-2017 IPR023614 Porin domain RG49_RS02980 a41335fe081d940f906c40544689ec2d 96 SUPERFAMILY SSF56935 22 92 1.86E-16 T 10-03-2017 RG49_RS02980 a41335fe081d940f906c40544689ec2d 96 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 2.4E-18 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS02980 a41335fe081d940f906c40544689ec2d 96 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 2.4E-18 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS14895 3826d5422af0d44c2985556a685a86b4 328 SUPERFAMILY SSF56112 6 327 1.9E-92 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS14895 3826d5422af0d44c2985556a685a86b4 328 Hamap MF_01497 Stress response kinase A [srkA]. 4 318 45.89 T 10-03-2017 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 RG49_RS14895 3826d5422af0d44c2985556a685a86b4 328 Gene3D G3DSA:3.90.1200.10 106 325 1.5E-46 T 10-03-2017 RG49_RS14895 3826d5422af0d44c2985556a685a86b4 328 Pfam PF01636 Phosphotransferase enzyme family 32 259 1.5E-43 T 10-03-2017 IPR002575 Aminoglycoside phosphotransferase RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 SMART SM00926 49 108 4.9E-10 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Gene3D G3DSA:2.20.25.90 45 111 2.5E-16 T 10-03-2017 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 SUPERFAMILY SSF53706 50 688 3.01E-173 T 10-03-2017 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 SUPERFAMILY SSF50692 679 808 1.45E-38 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Gene3D G3DSA:3.40.228.10 197 400 3.8E-82 T 10-03-2017 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 49 108 9.7E-15 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Pfam PF00384 Molybdopterin oxidoreductase 111 566 1.0E-95 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Gene3D G3DSA:2.40.40.20 663 808 1.0E-55 T 10-03-2017 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 723 750 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Pfam PF01568 Molydopterin dinucleotide binding domain 687 800 3.7E-27 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Gene3D G3DSA:3.40.50.740 112 196 3.2E-81 T 10-03-2017 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 Gene3D G3DSA:3.40.50.740 401 646 3.2E-81 T 10-03-2017 RG49_RS02140 b277b23eb8de8b3e33e68375fa5e01ff 808 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 10 808 0.0 T 10-03-2017 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 SUPERFAMILY SSF54826 41 158 1.54E-23 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 Hamap MF_01288 L-rhamnonate dehydratase [rhmD]. 1 401 79.429 T 10-03-2017 IPR023444 L-rhamnonate dehydratase GO:0050032 KEGG: 00051+4.2.1.90|MetaCyc: PWY-6713|MetaCyc: PWY-6714 RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 SMART SM00922 163 269 7.1E-8 T 10-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 Gene3D G3DSA:3.30.390.10 2 162 1.8E-43 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 132 157 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 Pfam PF13378 Enolase C-terminal domain-like 183 392 1.4E-36 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 Gene3D G3DSA:3.20.20.120 163 390 3.7E-57 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 SUPERFAMILY SSF51604 145 397 5.11E-55 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS23860 847059085d808ee7e5bcb3ba0d1aae48 401 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 67 157 4.5E-8 T 10-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain RG49_RS05775 d9c665a98377af5c68cca9648cbdf6ff 214 SUPERFAMILY SSF159270 19 213 1.07E-64 T 10-03-2017 IPR023373 YmcC-like domain RG49_RS05775 d9c665a98377af5c68cca9648cbdf6ff 214 Gene3D G3DSA:2.40.360.10 16 213 8.0E-82 T 10-03-2017 IPR023373 YmcC-like domain RG49_RS05775 d9c665a98377af5c68cca9648cbdf6ff 214 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 13 210 1.8E-67 T 10-03-2017 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 271 4.8E-28 T 10-03-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 SMART SM00893 5 180 2.1E-12 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 Gene3D G3DSA:3.40.50.620 3 167 3.2E-31 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 PIRSF PIRSF000089 3 312 4.7E-85 T 10-03-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 SUPERFAMILY SSF52402 6 181 2.93E-27 T 10-03-2017 RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 10-03-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 SUPERFAMILY SSF52467 189 309 6.95E-42 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 Pfam PF01012 Electron transfer flavoprotein domain 24 168 1.4E-18 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS01530 02f269fb351d6608be5ce850aaa31368 312 Gene3D G3DSA:3.40.50.1220 184 310 1.2E-47 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS06470 0b056dd34ac4246fd0fea3270d3d4735 375 SUPERFAMILY SSF53335 3 374 1.27E-53 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06470 0b056dd34ac4246fd0fea3270d3d4735 375 Gene3D G3DSA:3.40.50.150 180 373 1.4E-49 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06470 0b056dd34ac4246fd0fea3270d3d4735 375 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 208 374 1.8E-16 T 10-03-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 RG49_RS06470 0b056dd34ac4246fd0fea3270d3d4735 375 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 357 367 - T 10-03-2017 IPR030391 RNA methyltransferase TrmA, conserved site RG49_RS06470 0b056dd34ac4246fd0fea3270d3d4735 375 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 307 338 - T 10-03-2017 IPR030390 RNA methyltransferase TrmA, active site RG49_RS06470 0b056dd34ac4246fd0fea3270d3d4735 375 TIGRFAM TIGR02085 meth_trns_rumB: 23S rRNA (uracil-5-)-methyltransferase RumB 2 374 3.3E-222 T 10-03-2017 IPR011825 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC GO:0016070|GO:0016436 RG49_RS06470 0b056dd34ac4246fd0fea3270d3d4735 375 Hamap MF_01012 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC [rlmC]. 1 375 79.705 T 10-03-2017 IPR011825 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC GO:0016070|GO:0016436 RG49_RS04360 37bfc108960179714ca5be537ab44297 334 SMART SM00382 49 242 5.5E-18 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS04360 37bfc108960179714ca5be537ab44297 334 Pfam PF00005 ABC transporter 41 192 5.8E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS04360 37bfc108960179714ca5be537ab44297 334 SUPERFAMILY SSF52540 22 264 3.04E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04360 37bfc108960179714ca5be537ab44297 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 311 9.7E-19 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS04360 37bfc108960179714ca5be537ab44297 334 Gene3D G3DSA:3.40.50.300 10 266 1.9E-80 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04360 37bfc108960179714ca5be537ab44297 334 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS04360 37bfc108960179714ca5be537ab44297 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 329 1.2E-27 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS08095 1a3d18fa4a35b13df73e9a69b4707a58 187 SUPERFAMILY SSF52833 1 186 6.41E-54 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08095 1a3d18fa4a35b13df73e9a69b4707a58 187 PIRSF PIRSF000239 1 187 2.7E-50 T 10-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 RG49_RS08095 1a3d18fa4a35b13df73e9a69b4707a58 187 Pfam PF00578 AhpC/TSA family 10 133 5.8E-33 T 10-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 RG49_RS08095 1a3d18fa4a35b13df73e9a69b4707a58 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 2.7E-103 T 10-03-2017 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 RG49_RS08095 1a3d18fa4a35b13df73e9a69b4707a58 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 181 1.8E-6 T 10-03-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 RG49_RS08095 1a3d18fa4a35b13df73e9a69b4707a58 187 Gene3D G3DSA:3.40.30.10 4 183 2.4E-59 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS04750 4323aef8aaf07a46c6b111e4c4c6c708 303 Gene3D G3DSA:1.20.1170.10 1 303 5.8E-205 T 10-03-2017 RG49_RS04750 4323aef8aaf07a46c6b111e4c4c6c708 303 SUPERFAMILY SSF58100 1 298 7.32E-184 T 10-03-2017 RG49_RS04750 4323aef8aaf07a46c6b111e4c4c6c708 303 Pfam PF06109 Haemolysin E (HlyE) 13 293 9.2E-125 T 10-03-2017 IPR027018 Hemolysin E GO:0009405|GO:0044179 RG49_RS19005 c610ae9ac87f5fdbe2a6351f32dc6d21 426 TIGRFAM TIGR02810 agaZ_gatZ: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit 6 424 3.9E-217 T 10-03-2017 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 RG49_RS19005 c610ae9ac87f5fdbe2a6351f32dc6d21 426 Pfam PF08013 Tagatose 6 phosphate kinase 4 423 7.3E-201 T 10-03-2017 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 RG49_RS19005 c610ae9ac87f5fdbe2a6351f32dc6d21 426 Gene3D G3DSA:1.10.400.20 295 409 1.2E-54 T 10-03-2017 RG49_RS19005 c610ae9ac87f5fdbe2a6351f32dc6d21 426 Hamap MF_01295 D-tagatose-1,6-bisphosphate aldolase subunit KbaZ [kbaZ]. 1 426 81.684 T 10-03-2017 IPR023435 D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit KbaZ RG49_RS19005 c610ae9ac87f5fdbe2a6351f32dc6d21 426 PIRSF PIRSF009264 1 426 1.8E-211 T 10-03-2017 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 RG49_RS19005 c610ae9ac87f5fdbe2a6351f32dc6d21 426 SUPERFAMILY SSF51569 4 423 4.4E-171 T 10-03-2017 RG49_RS19005 c610ae9ac87f5fdbe2a6351f32dc6d21 426 Gene3D G3DSA:3.20.20.70 5 294 2.7E-146 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS19535 aa212907f314017af7197509ecdb308b 96 Pfam PF04380 Membrane fusogenic activity 1 77 1.1E-28 T 10-03-2017 IPR007475 Membrane fusogenic activity RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 SUPERFAMILY SSF55486 204 450 2.38E-75 T 10-03-2017 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 Pfam PF11940 Domain of unknown function (DUF3458) 459 827 2.7E-136 T 10-03-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 Pfam PF01433 Peptidase family M1 48 384 5.9E-70 T 10-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 SUPERFAMILY SSF63737 1 193 1.22E-45 T 10-03-2017 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 Gene3D G3DSA:1.25.50.10 547 870 2.0E-124 T 10-03-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 12 869 0.0 T 10-03-2017 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 Gene3D G3DSA:1.10.390.10 308 451 1.1E-35 T 10-03-2017 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 258 268 7.2E-9 T 10-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 176 191 7.2E-9 T 10-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 313 325 7.2E-9 T 10-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 126 141 7.2E-9 T 10-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 RG49_RS06065 8a2d4bdfd18bf8b30cf5426d05a5b344 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 294 309 7.2E-9 T 10-03-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 RG49_RS20015 fe7522725fd4681564e6fdb4eff72576 123 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20015 fe7522725fd4681564e6fdb4eff72576 123 Gene3D G3DSA:3.30.1300.30 32 116 5.5E-29 T 10-03-2017 RG49_RS20015 fe7522725fd4681564e6fdb4eff72576 123 SUPERFAMILY SSF54523 36 115 7.46E-21 T 10-03-2017 RG49_RS20015 fe7522725fd4681564e6fdb4eff72576 123 TIGRFAM TIGR01707 gspI: type II secretion system protein I 4 102 5.1E-26 T 10-03-2017 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 RG49_RS20015 fe7522725fd4681564e6fdb4eff72576 123 Pfam PF02501 Type II secretion system (T2SS), protein I 38 116 4.9E-20 T 10-03-2017 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 RG49_RS20015 fe7522725fd4681564e6fdb4eff72576 123 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 25 1.5E-8 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20015 fe7522725fd4681564e6fdb4eff72576 123 Pfam PF13633 Prokaryotic N-terminal methylation site 2 26 2.3E-9 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS09035 6f239857fde2e286b67a868ac42113d0 324 PRINTS PR00069 Aldo-keto reductase signature 142 159 1.7E-6 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS09035 6f239857fde2e286b67a868ac42113d0 324 PRINTS PR00069 Aldo-keto reductase signature 230 254 1.7E-6 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS09035 6f239857fde2e286b67a868ac42113d0 324 PRINTS PR00069 Aldo-keto reductase signature 111 129 1.7E-6 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS09035 6f239857fde2e286b67a868ac42113d0 324 PRINTS PR00069 Aldo-keto reductase signature 47 71 1.7E-6 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS09035 6f239857fde2e286b67a868ac42113d0 324 Pfam PF00248 Aldo/keto reductase family 15 312 1.5E-74 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS09035 6f239857fde2e286b67a868ac42113d0 324 Gene3D G3DSA:3.20.20.100 9 322 4.0E-106 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS09035 6f239857fde2e286b67a868ac42113d0 324 SUPERFAMILY SSF51430 1 321 1.57E-102 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS15575 35bab65849b37f27d224829abaa874fa 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 304 1.8E-17 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS15575 35bab65849b37f27d224829abaa874fa 319 SUPERFAMILY SSF161098 27 303 1.3E-32 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS15575 35bab65849b37f27d224829abaa874fa 319 Gene3D G3DSA:1.10.3720.10 25 316 5.3E-36 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS15575 35bab65849b37f27d224829abaa874fa 319 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 18 311 2.2E-92 T 10-03-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 RG49_RS25255 44b91457c2d37cd6907ea14537e8576a 214 Gene3D G3DSA:3.20.20.70 2 209 3.6E-73 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS25255 44b91457c2d37cd6907ea14537e8576a 214 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 198 4.1E-70 T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS25255 44b91457c2d37cd6907ea14537e8576a 214 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 202 1.4E-70 T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS25255 44b91457c2d37cd6907ea14537e8576a 214 PIRSF PIRSF001461 1 214 2.2E-72 T 10-03-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS25255 44b91457c2d37cd6907ea14537e8576a 214 SUPERFAMILY SSF51366 1 205 2.47E-61 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS25255 44b91457c2d37cd6907ea14537e8576a 214 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 21 388 3.0E-168 T 10-03-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 Pfam PF00285 Citrate synthase, C-terminal domain 22 370 8.4E-116 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 Gene3D G3DSA:1.10.230.10 251 335 5.3E-28 T 10-03-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 SUPERFAMILY SSF48256 22 382 4.45E-124 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 PRINTS PR00143 Citrate synthase signature 139 152 1.8E-37 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 PRINTS PR00143 Citrate synthase signature 211 239 1.8E-37 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 PRINTS PR00143 Citrate synthase signature 341 355 1.8E-37 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 PRINTS PR00143 Citrate synthase signature 264 284 1.8E-37 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 PRINTS PR00143 Citrate synthase signature 321 337 1.8E-37 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 PRINTS PR00143 Citrate synthase signature 189 204 1.8E-37 T 10-03-2017 IPR002020 Citrate synthase GO:0046912 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 PIRSF PIRSF001369 15 389 4.6E-111 T 10-03-2017 IPR024176 Citrate synthase, bacterial-type RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 Gene3D G3DSA:1.10.580.10 26 250 8.8E-79 T 10-03-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 RG49_RS09475 d7cbd5caf74a75301da0d8b5cae459f3 389 ProSitePatterns PS00480 Citrate synthase signature. 271 283 - T 10-03-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 RG49_RS21370 c46cc044abcf0b53e91c75ded33d4a87 454 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 7 453 1.9E-103 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS21370 c46cc044abcf0b53e91c75ded33d4a87 454 PIRSF PIRSF002746 1 454 3.2E-152 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS21370 c46cc044abcf0b53e91c75ded33d4a87 454 Pfam PF02447 GntP family permease 5 453 1.4E-155 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS23005 10f1a1a47a2b2b016072c5e3bb34b0ad 277 Gene3D G3DSA:1.10.3720.10 19 273 8.7E-55 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23005 10f1a1a47a2b2b016072c5e3bb34b0ad 277 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 5 269 5.8E-116 T 10-03-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 RG49_RS23005 10f1a1a47a2b2b016072c5e3bb34b0ad 277 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 9 271 1.7E-113 T 10-03-2017 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 RG49_RS23005 10f1a1a47a2b2b016072c5e3bb34b0ad 277 SUPERFAMILY SSF161098 16 264 1.21E-57 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23005 10f1a1a47a2b2b016072c5e3bb34b0ad 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 274 3.0E-34 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS10430 29c48c733044c909a7c78514c8d28b52 178 SUPERFAMILY SSF109604 1 173 9.42E-39 T 10-03-2017 RG49_RS10430 29c48c733044c909a7c78514c8d28b52 178 Gene3D G3DSA:1.10.3210.10 1 173 9.8E-51 T 10-03-2017 IPR006674 HD domain RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 SUPERFAMILY SSF82866 337 349 2.75E-40 T 10-03-2017 RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 SUPERFAMILY SSF82866 410 606 2.75E-40 T 10-03-2017 RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 Pfam PF02355 Protein export membrane protein 433 601 2.0E-15 T 10-03-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 Gene3D G3DSA:1.20.1640.10 443 610 3.9E-25 T 10-03-2017 RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 345 594 2.5E-84 T 10-03-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 615 51.126 T 10-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 Pfam PF07549 SecD/SecF GG Motif 120 140 5.0E-6 T 10-03-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 Pfam PF13721 SecD export protein N-terminal TM region 2 103 7.6E-38 T 10-03-2017 IPR027398 SecD export protein N-terminal TM domain RG49_RS09090 2f3b50bac6c257dd6c7260ea17b99a01 615 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 601 1.4E-151 T 10-03-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 RG49_RS18005 af999efcbd0a2375432bf21906bd585c 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 13 198 5.6E-75 T 10-03-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18005 af999efcbd0a2375432bf21906bd585c 201 Pfam PF00573 Ribosomal protein L4/L1 family 13 198 3.0E-64 T 10-03-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 RG49_RS18005 af999efcbd0a2375432bf21906bd585c 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 201 33.976 T 10-03-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18005 af999efcbd0a2375432bf21906bd585c 201 SUPERFAMILY SSF52166 10 200 7.06E-73 T 10-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 RG49_RS18005 af999efcbd0a2375432bf21906bd585c 201 Gene3D G3DSA:3.40.1370.10 54 201 2.5E-59 T 10-03-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 709 736 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 Pfam PF01568 Molydopterin dinucleotide binding domain 670 779 1.3E-23 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 493 510 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 SUPERFAMILY SSF50692 661 806 1.08E-38 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 Gene3D G3DSA:2.40.40.20 646 801 1.5E-54 T 10-03-2017 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 Gene3D G3DSA:3.40.228.10 182 392 6.5E-61 T 10-03-2017 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 Gene3D G3DSA:3.40.50.740 393 494 2.4E-42 T 10-03-2017 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 Gene3D G3DSA:3.40.50.740 77 178 2.4E-42 T 10-03-2017 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 Pfam PF00384 Molybdopterin oxidoreductase 84 550 6.0E-103 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 41 808 0.0 T 10-03-2017 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 SUPERFAMILY SSF53706 42 657 7.72E-160 T 10-03-2017 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 Gene3D G3DSA:3.90.55.10 495 601 4.7E-37 T 10-03-2017 RG49_RS00555 069646567eabdff900a553d25d5c1a53 809 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 31 2.1E-6 T 10-03-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 SUPERFAMILY SSF51735 1 160 1.29E-38 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 Gene3D G3DSA:3.40.50.720 2 163 2.7E-51 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 Gene3D G3DSA:1.10.1040.10 164 292 1.5E-36 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 SUPERFAMILY SSF48179 163 286 8.96E-31 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 Hamap MF_01913 3-sulfolactaldehyde reductase. 1 292 72.979 T 10-03-2017 IPR030876 3-sulfolactaldehyde reductase GO:0061596|GO:1902777 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|MetaCyc: PWY-7446 RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 10-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 PIRSF PIRSF000103 1 295 1.9E-96 T 10-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 8.5E-26 T 10-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 RG49_RS14760 9a6b943c07a02ec2f053a4477f2200b7 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 160 3.4E-44 T 10-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 Gene3D G3DSA:3.40.50.510 3 133 1.5E-49 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 Gene3D G3DSA:3.40.35.10 162 321 1.1E-67 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 Pfam PF03830 PTS system sorbose subfamily IIB component 164 310 1.4E-55 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 164 311 1.1E-56 T 10-03-2017 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 SUPERFAMILY SSF52728 162 321 9.16E-55 T 10-03-2017 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 Pfam PF03610 PTS system fructose IIA component 5 116 1.9E-35 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 2 117 3.7E-52 T 10-03-2017 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 RG49_RS00880 36ec77e222bfe6f5d9c347528c4e7c24 323 SUPERFAMILY SSF53062 3 128 1.09E-37 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 PIRSF PIRSF002401 1 376 3.9E-140 T 10-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 SUPERFAMILY SSF52540 151 336 9.24E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 Hamap MF_01454 GTPase Obg [obg]. 2 333 48.475 T 10-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.5E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.5E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.5E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.5E-34 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 Gene3D G3DSA:3.40.50.300 160 348 2.9E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 Pfam PF01926 50S ribosome-binding GTPase 162 284 1.0E-23 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 Pfam PF01018 GTP1/OBG 3 157 1.3E-60 T 10-03-2017 IPR006169 GTP1/OBG domain GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 10-03-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 331 2.9E-148 T 10-03-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 SUPERFAMILY SSF82051 2 157 1.12E-56 T 10-03-2017 IPR006169 GTP1/OBG domain GO:0005525 RG49_RS18725 eed02db95ce28bb7c37465a5fac24899 390 Gene3D G3DSA:2.70.210.12 2 156 1.4E-60 T 10-03-2017 IPR006169 GTP1/OBG domain GO:0005525 RG49_RS09225 81df583a371326a910430ba1314133b7 86 Hamap MF_01198 Anti-adapter protein IraP [iraP]. 1 86 26.572 T 10-03-2017 IPR019732 Sigma-S stabilisation anti-adaptor protein GO:0005737 RG49_RS09225 81df583a371326a910430ba1314133b7 86 Pfam PF10796 Sigma-S stabilisation anti-adaptor protein 1 85 7.8E-32 T 10-03-2017 IPR019732 Sigma-S stabilisation anti-adaptor protein GO:0005737 RG49_RS06050 878cc4667e4f7c30d61cfb1f985a5b47 381 SUPERFAMILY SSF51679 3 349 9.16E-98 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS06050 878cc4667e4f7c30d61cfb1f985a5b47 381 Pfam PF00296 Luciferase-like monooxygenase 5 326 3.9E-86 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS06050 878cc4667e4f7c30d61cfb1f985a5b47 381 Gene3D G3DSA:3.20.20.30 3 253 2.6E-103 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS06050 878cc4667e4f7c30d61cfb1f985a5b47 381 Gene3D G3DSA:3.20.20.30 287 350 2.6E-103 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS06050 878cc4667e4f7c30d61cfb1f985a5b47 381 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 4 379 71.016 T 10-03-2017 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 RG49_RS06050 878cc4667e4f7c30d61cfb1f985a5b47 381 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 4 349 1.5E-190 T 10-03-2017 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 SUPERFAMILY SSF69189 282 375 1.28E-21 T 10-03-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 SMART SM00936 282 373 1.6E-26 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 282 372 2.0E-20 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 Gene3D G3DSA:2.60.410.10 283 373 9.6E-27 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 62 73 1.8E-17 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 121 138 1.8E-17 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 148 161 1.8E-17 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 262 4.3E-99 T 10-03-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 SUPERFAMILY SSF56601 4 282 3.8E-76 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS25160 bce8cefbf54cb74755507224c0f9cdea 388 Gene3D G3DSA:3.40.710.10 28 282 1.5E-94 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS01865 1c961799c8e66571363c81642cf2ab91 287 SUPERFAMILY SSF53613 1 281 2.49E-77 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS01865 1c961799c8e66571363c81642cf2ab91 287 Gene3D G3DSA:3.40.1190.20 1 286 7.1E-89 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS01865 1c961799c8e66571363c81642cf2ab91 287 Hamap MF_01639 Pyridoxal kinase PdxY [pdxY]. 2 287 54.4 T 10-03-2017 IPR023685 Pyridoxal kinase PdxY GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282 RG49_RS01865 1c961799c8e66571363c81642cf2ab91 287 Pfam PF08543 Phosphomethylpyrimidine kinase 68 256 1.2E-15 T 10-03-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 RG49_RS01865 1c961799c8e66571363c81642cf2ab91 287 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 1 286 2.0E-146 T 10-03-2017 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS22330 62087d101e18ced6a99516e659ab57c9 327 Gene3D G3DSA:3.40.50.2300 157 312 8.2E-25 T 10-03-2017 RG49_RS22330 62087d101e18ced6a99516e659ab57c9 327 Gene3D G3DSA:3.40.50.2300 31 156 2.8E-27 T 10-03-2017 RG49_RS22330 62087d101e18ced6a99516e659ab57c9 327 SUPERFAMILY SSF53822 29 312 8.16E-46 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS22330 62087d101e18ced6a99516e659ab57c9 327 Pfam PF13407 Periplasmic binding protein domain 40 294 3.1E-30 T 10-03-2017 IPR025997 Periplasmic binding protein RG49_RS02765 39991c998b0d42cff189711999c8635a 544 SUPERFAMILY SSF52540 189 460 7.16E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02765 39991c998b0d42cff189711999c8635a 544 Gene3D G3DSA:3.40.50.300 384 471 3.7E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02765 39991c998b0d42cff189711999c8635a 544 Gene3D G3DSA:3.40.50.300 190 249 1.1E-4 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02765 39991c998b0d42cff189711999c8635a 544 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 341 456 2.3E-14 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS12830 e182e2eb845270a8bcbd1103a8acf778 220 Hamap MF_01606 Iron-sulfur cluster repair protein YtfE [ytfE]. 1 220 52.203 T 10-03-2017 IPR023742 Iron-sulfur cluster repair protein YftE GO:0006950|GO:0030091 RG49_RS12830 e182e2eb845270a8bcbd1103a8acf778 220 Pfam PF01814 Hemerythrin HHE cation binding domain 77 216 1.1E-27 T 10-03-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 RG49_RS12830 e182e2eb845270a8bcbd1103a8acf778 220 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 8 216 1.0E-80 T 10-03-2017 IPR019903 Repair of iron centres family RG49_RS12830 e182e2eb845270a8bcbd1103a8acf778 220 Pfam PF04405 Domain of Unknown function (DUF542) 5 58 1.4E-20 T 10-03-2017 IPR019903 Repair of iron centres family RG49_RS12830 e182e2eb845270a8bcbd1103a8acf778 220 Gene3D G3DSA:1.20.120.520 78 217 1.5E-26 T 10-03-2017 RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 Gene3D G3DSA:1.10.10.10 126 223 9.8E-32 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 SMART SM00448 1 112 1.8E-39 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 SUPERFAMILY SSF52172 1 118 1.71E-38 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 SUPERFAMILY SSF46894 126 223 1.76E-29 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 1.3E-97 T 10-03-2017 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 Gene3D G3DSA:3.40.50.2300 1 119 9.7E-37 T 10-03-2017 RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 Pfam PF00072 Response regulator receiver domain 4 113 5.2E-27 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 SMART SM00862 146 221 1.2E-25 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS08320 4dd31fadffaa9a241f38483c086aa107 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 6.1E-26 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS22755 d0a863af2c08e2bba635085fb5147e18 156 Gene3D G3DSA:3.40.30.10 2 155 2.8E-51 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS22755 d0a863af2c08e2bba635085fb5147e18 156 SUPERFAMILY SSF52833 3 154 3.14E-50 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS22755 d0a863af2c08e2bba635085fb5147e18 156 Pfam PF00578 AhpC/TSA family 7 134 4.4E-39 T 10-03-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 RG49_RS22755 d0a863af2c08e2bba635085fb5147e18 156 PIRSF PIRSF000239 1 153 1.3E-17 T 10-03-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 RG49_RS02525 2cf69a4dd912f02f130d4313ca35a9d3 681 Gene3D G3DSA:1.20.1050.40 12 143 1.7E-17 T 10-03-2017 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal RG49_RS02525 2cf69a4dd912f02f130d4313ca35a9d3 681 SUPERFAMILY SSF55486 5 679 4.12E-171 T 10-03-2017 RG49_RS02525 2cf69a4dd912f02f130d4313ca35a9d3 681 Pfam PF01432 Peptidase family M3 230 678 1.2E-146 T 10-03-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 RG49_RS02525 2cf69a4dd912f02f130d4313ca35a9d3 681 Gene3D G3DSA:3.40.390.10 362 504 3.0E-51 T 10-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 RG49_RS02525 2cf69a4dd912f02f130d4313ca35a9d3 681 Gene3D G3DSA:1.10.1370.10 146 352 5.2E-110 T 10-03-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 RG49_RS02525 2cf69a4dd912f02f130d4313ca35a9d3 681 Gene3D G3DSA:1.10.1370.10 505 679 5.2E-110 T 10-03-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 RG49_RS15485 3f68597921753db6de1a80dbcc936058 483 Pfam PF05762 VWA domain containing CoxE-like protein 307 458 1.7E-10 T 10-03-2017 IPR008912 Uncharacterised protein family CoxE-like RG49_RS15485 3f68597921753db6de1a80dbcc936058 483 Hamap MF_01626 Protein ViaA [viaA]. 1 483 60.472 T 10-03-2017 IPR023481 Uncharacterised protein family ViaA RG49_RS15485 3f68597921753db6de1a80dbcc936058 483 SMART SM00327 319 483 2.1E-13 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS15485 3f68597921753db6de1a80dbcc936058 483 SUPERFAMILY SSF53300 318 459 4.79E-19 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS11645 25c176104b8a298c5e47bbc96315ab21 95 PIRSF PIRSF036548 1 95 6.8E-39 T 10-03-2017 IPR012206 Ferredoxin-like, FixX GO:0005506 RG49_RS11645 25c176104b8a298c5e47bbc96315ab21 95 SUPERFAMILY SSF54862 40 90 2.99E-8 T 10-03-2017 RG49_RS11645 25c176104b8a298c5e47bbc96315ab21 95 Gene3D G3DSA:3.30.70.20 40 69 1.8E-5 T 10-03-2017 RG49_RS24825 ad694cea7c18f1430b157f3ad62c6416 646 Gene3D G3DSA:1.10.150.20 516 551 4.4E-5 T 10-03-2017 RG49_RS24825 ad694cea7c18f1430b157f3ad62c6416 646 PIRSF PIRSF030823 1 646 0.0 T 10-03-2017 IPR016960 Uncharacterised conserved protein UCP030823, kinase, HhH DNA-binding RG49_RS24825 ad694cea7c18f1430b157f3ad62c6416 646 Gene3D G3DSA:1.10.510.10 112 223 8.6E-7 T 10-03-2017 RG49_RS24825 ad694cea7c18f1430b157f3ad62c6416 646 SUPERFAMILY SSF56112 83 223 1.13E-11 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 Gene3D G3DSA:3.40.190.10 27 150 5.2E-12 T 10-03-2017 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 314 340 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 51 72 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 127 143 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 78 92 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 269 288 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 158 172 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 181 200 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 219 238 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 35 51 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 94 107 3.2E-76 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 PIRSF PIRSF019574 1 370 8.0E-144 T 10-03-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 Pfam PF13416 Bacterial extracellular solute-binding protein 46 335 2.6E-35 T 10-03-2017 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 SUPERFAMILY SSF53850 29 369 2.22E-105 T 10-03-2017 RG49_RS06495 1c34f98313681df17cdf3fcd6c7027b4 370 Gene3D G3DSA:3.40.190.10 151 319 5.8E-76 T 10-03-2017 RG49_RS09590 394696d07fdee0756d69ffc6e6294d60 92 SUPERFAMILY SSF46894 15 75 3.74E-11 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS09590 394696d07fdee0756d69ffc6e6294d60 92 Pfam PF00196 Bacterial regulatory proteins, luxR family 25 73 9.6E-12 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS09590 394696d07fdee0756d69ffc6e6294d60 92 Gene3D G3DSA:1.10.10.10 26 73 2.9E-10 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09590 394696d07fdee0756d69ffc6e6294d60 92 SMART SM00421 22 79 2.3E-10 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS09590 394696d07fdee0756d69ffc6e6294d60 92 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 39 55 2.9E-5 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS09590 394696d07fdee0756d69ffc6e6294d60 92 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 25 39 2.9E-5 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS09590 394696d07fdee0756d69ffc6e6294d60 92 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 55 67 2.9E-5 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS08175 83ef19341687c2c11f8d33c19564f079 318 Pfam PF01497 Periplasmic binding protein 49 297 1.8E-32 T 10-03-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 RG49_RS08175 83ef19341687c2c11f8d33c19564f079 318 SUPERFAMILY SSF53807 31 317 5.1E-50 T 10-03-2017 RG49_RS08175 83ef19341687c2c11f8d33c19564f079 318 Gene3D G3DSA:3.40.50.1980 158 318 5.5E-45 T 10-03-2017 RG49_RS08175 83ef19341687c2c11f8d33c19564f079 318 Gene3D G3DSA:3.40.50.1980 29 157 6.1E-26 T 10-03-2017 RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 SUPERFAMILY SSF52540 270 314 8.3E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 SUPERFAMILY SSF52540 44 220 8.3E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 SUPERFAMILY SSF52540 348 421 8.3E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 Gene3D G3DSA:3.40.50.300 18 234 1.1E-42 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 Gene3D G3DSA:3.40.50.300 286 314 7.1E-26 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 Gene3D G3DSA:3.40.50.300 348 439 7.1E-26 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 Pfam PF00271 Helicase conserved C-terminal domain 349 417 7.0E-12 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 Pfam PF08494 DEAD/H associated 679 867 4.8E-70 T 10-03-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 SMART SM00487 26 249 1.5E-37 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 SMART SM00382 43 404 9.4E-4 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 SMART SM00490 306 417 1.5E-13 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS01780 0a8aa5f42ef9efe50ebc988e2391a8e8 1538 Pfam PF00270 DEAD/DEAH box helicase 31 218 1.5E-26 T 10-03-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 RG49_RS25045 459e85eb24c6e0fac7ce4873984602eb 269 SUPERFAMILY SSF53448 3 266 9.6E-41 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS25045 459e85eb24c6e0fac7ce4873984602eb 269 Pfam PF00535 Glycosyl transferase family 2 4 149 5.2E-18 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS25045 459e85eb24c6e0fac7ce4873984602eb 269 Gene3D G3DSA:3.90.550.10 2 226 6.9E-42 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 535 27.015 T 10-03-2017 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 Pfam PF02096 60Kd inner membrane protein 354 533 1.3E-60 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR01900 YidC translocation/secretion protein signature 339 355 5.3E-30 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR01900 YidC translocation/secretion protein signature 488 512 5.3E-30 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR01900 YidC translocation/secretion protein signature 468 483 5.3E-30 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 353 533 4.8E-69 T 10-03-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 352 4.1E-118 T 10-03-2017 IPR028053 Membrane insertase YidC, N-terminal RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 251 266 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 415 438 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 324 344 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 66 87 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 499 522 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 158 178 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 217 235 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 PRINTS PR00701 60kDa inner membrane protein signature 462 484 1.3E-109 T 10-03-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 RG49_RS15690 d9725ef94d90a026d20113b1739c3cf0 548 Pfam PF14849 YidC periplasmic domain 61 343 7.3E-90 T 10-03-2017 IPR028053 Membrane insertase YidC, N-terminal RG49_RS11390 89c302565302e97261ffc4ee483d4770 276 Pfam PF08478 POTRA domain, FtsQ-type 56 126 1.6E-19 T 10-03-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type RG49_RS11390 89c302565302e97261ffc4ee483d4770 276 Pfam PF03799 Cell division protein FtsQ 130 247 1.6E-27 T 10-03-2017 IPR005548 Cell division protein FtsQ/DivIB RG49_RS11390 89c302565302e97261ffc4ee483d4770 276 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 25 255 26.132 T 10-03-2017 IPR026579 Cell division protein FtsQ GO:0090529 RG49_RS11070 84438753d7cba90f0b21ff4792580f03 265 Gene3D G3DSA:3.40.50.300 14 240 1.2E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11070 84438753d7cba90f0b21ff4792580f03 265 Pfam PF00005 ABC transporter 27 176 7.2E-33 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS11070 84438753d7cba90f0b21ff4792580f03 265 SMART SM00382 36 224 3.4E-16 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS11070 84438753d7cba90f0b21ff4792580f03 265 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS11070 84438753d7cba90f0b21ff4792580f03 265 SUPERFAMILY SSF52540 13 238 2.61E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08045 1e4107932e3c67ed9fa7da427040ddc2 183 Pfam PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 13 176 4.6E-54 T 10-03-2017 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 RG49_RS08045 1e4107932e3c67ed9fa7da427040ddc2 183 TIGRFAM TIGR03124 citrate_citX: holo-ACP synthase CitX 13 175 2.9E-61 T 10-03-2017 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 RG49_RS08045 1e4107932e3c67ed9fa7da427040ddc2 183 Hamap MF_00398 Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase [citX]. 4 181 35.705 T 10-03-2017 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 RG49_RS14670 2b29309574224a030e8ca5a8ec155f4c 582 Pfam PF08279 HTH domain 5 60 2.5E-9 T 10-03-2017 IPR013196 Helix-turn-helix, type 11 RG49_RS14670 2b29309574224a030e8ca5a8ec155f4c 582 SUPERFAMILY SSF46785 1 42 2.72E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14670 2b29309574224a030e8ca5a8ec155f4c 582 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 455 561 3.3E-12 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS14670 2b29309574224a030e8ca5a8ec155f4c 582 Gene3D G3DSA:1.10.10.10 1 61 1.8E-9 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14670 2b29309574224a030e8ca5a8ec155f4c 582 Gene3D G3DSA:3.40.930.10 455 579 1.4E-11 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS14670 2b29309574224a030e8ca5a8ec155f4c 582 SUPERFAMILY SSF55804 453 580 6.15E-17 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS19540 7a0ee251aebd17f34ee42e9d84f7869d 217 Gene3D G3DSA:3.90.870.10 10 214 4.2E-95 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS19540 7a0ee251aebd17f34ee42e9d84f7869d 217 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 17 208 9.0E-83 T 10-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS19540 7a0ee251aebd17f34ee42e9d84f7869d 217 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 209 1.1E-86 T 10-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS19540 7a0ee251aebd17f34ee42e9d84f7869d 217 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 11 213 43.303 T 10-03-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 RG49_RS19540 7a0ee251aebd17f34ee42e9d84f7869d 217 SUPERFAMILY SSF55821 7 213 5.04E-86 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS16210 a41aed07098f4404e71df8cb983f6b25 222 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 171 176 - T 10-03-2017 IPR020891 Uncharacterised protein family UPF0758, conserved site RG49_RS16210 a41aed07098f4404e71df8cb983f6b25 222 Hamap MF_00018 UPF0758 protein YicR [yicR]. 2 222 53.494 T 10-03-2017 IPR022820 Uncharacterised protein family UPF0758, YicR subfamily RG49_RS16210 a41aed07098f4404e71df8cb983f6b25 222 Gene3D G3DSA:3.40.140.10 99 222 3.0E-49 T 10-03-2017 RG49_RS16210 a41aed07098f4404e71df8cb983f6b25 222 TIGRFAM TIGR00608 radc: DNA repair protein RadC 9 222 1.6E-97 T 10-03-2017 IPR001405 RadC protein RG49_RS16210 a41aed07098f4404e71df8cb983f6b25 222 Pfam PF04002 RadC-like JAB domain 103 220 1.1E-43 T 10-03-2017 IPR025657 RadC-like JAB domain RG49_RS16210 a41aed07098f4404e71df8cb983f6b25 222 SUPERFAMILY SSF47781 17 85 4.31E-8 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS01220 24cd8247be640d2cd90e0b61801af68f 388 Pfam PF13416 Bacterial extracellular solute-binding protein 62 340 9.4E-23 T 10-03-2017 RG49_RS01220 24cd8247be640d2cd90e0b61801af68f 388 PIRSF PIRSF029172 1 388 1.0E-185 T 10-03-2017 IPR027020 Protein ynjB RG49_RS01220 24cd8247be640d2cd90e0b61801af68f 388 Gene3D G3DSA:3.40.190.10 155 313 3.2E-6 T 10-03-2017 RG49_RS01220 24cd8247be640d2cd90e0b61801af68f 388 SUPERFAMILY SSF53850 32 385 1.3E-32 T 10-03-2017 RG49_RS01220 24cd8247be640d2cd90e0b61801af68f 388 Gene3D G3DSA:3.40.190.10 31 151 2.2E-16 T 10-03-2017 RG49_RS01220 24cd8247be640d2cd90e0b61801af68f 388 Gene3D G3DSA:3.40.190.10 314 352 2.2E-16 T 10-03-2017 RG49_RS06840 9b568b9f39106f08cda8f1a37b906e8e 782 SUPERFAMILY SSF141868 532 773 3.14E-68 T 10-03-2017 IPR001633 EAL domain RG49_RS06840 9b568b9f39106f08cda8f1a37b906e8e 782 SMART SM00052 526 772 3.8E-105 T 10-03-2017 IPR001633 EAL domain RG49_RS06840 9b568b9f39106f08cda8f1a37b906e8e 782 Pfam PF17153 Periplasmic sensor domain, extracellular 35 150 4.8E-56 T 10-03-2017 IPR033418 Periplasmic sensor domain, extracellular RG49_RS06840 9b568b9f39106f08cda8f1a37b906e8e 782 Gene3D G3DSA:3.20.20.450 530 773 1.3E-69 T 10-03-2017 IPR001633 EAL domain RG49_RS06840 9b568b9f39106f08cda8f1a37b906e8e 782 Pfam PF00563 EAL domain 532 767 1.4E-63 T 10-03-2017 IPR001633 EAL domain RG49_RS06560 9448cfbb44f0ff02b184b083c3e3bff3 39 Pfam PF06528 Phage P2 GpE 1 37 1.6E-19 T 10-03-2017 IPR009493 Burkholderia phage phiE202, Gp27 RG49_RS01020 9ecc1d8c1c619afd50682cff8e257c4f 84 Pfam PF03891 Domain of unknown function (DUF333) 32 78 9.8E-19 T 10-03-2017 IPR005590 Protein of unknown function DUF333 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 Pfam PF01218 Coproporphyrinogen III oxidase 7 299 5.9E-134 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 SUPERFAMILY SSF102886 3 299 1.31E-139 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 2 275 59.579 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PIRSF PIRSF000166 1 299 6.0E-130 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PRINTS PR00073 Coprogen oxidase signature 123 145 1.4E-90 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PRINTS PR00073 Coprogen oxidase signature 160 189 1.4E-90 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PRINTS PR00073 Coprogen oxidase signature 260 286 1.4E-90 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PRINTS PR00073 Coprogen oxidase signature 29 45 1.4E-90 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PRINTS PR00073 Coprogen oxidase signature 232 259 1.4E-90 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PRINTS PR00073 Coprogen oxidase signature 46 67 1.4E-90 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 PRINTS PR00073 Coprogen oxidase signature 88 112 1.4E-90 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 164 188 - T 10-03-2017 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS22945 290773f2e578924a6ead21a0f9af21b8 299 Gene3D G3DSA:3.40.1500.10 3 299 1.0E-138 T 10-03-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 SUPERFAMILY SSF56634 47 584 5.76E-225 T 10-03-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 Gene3D G3DSA:3.40.50.880 600 753 2.1E-48 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 Pfam PF06628 Catalase-related immune-responsive 499 562 3.1E-17 T 10-03-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 Pfam PF00199 Catalase 81 466 5.4E-176 T 10-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 SMART SM01060 81 469 7.6E-274 T 10-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 SUPERFAMILY SSF52317 599 749 2.94E-15 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 Gene3D G3DSA:2.40.180.10 59 436 4.8E-180 T 10-03-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 411 419 - T 10-03-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 ProSitePatterns PS00438 Catalase proximal active site signature. 117 133 - T 10-03-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 PIRSF PIRSF038927 42 751 0.0 T 10-03-2017 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 PRINTS PR00067 Catalase signature 157 175 1.0E-65 T 10-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 PRINTS PR00067 Catalase signature 178 195 1.0E-65 T 10-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 PRINTS PR00067 Catalase signature 366 393 1.0E-65 T 10-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 PRINTS PR00067 Catalase signature 94 117 1.0E-65 T 10-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 PRINTS PR00067 Catalase signature 398 424 1.0E-65 T 10-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS01345 6a26ee277e1e8171e11456e762cea851 753 PRINTS PR00067 Catalase signature 197 215 1.0E-65 T 10-03-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 RG49_RS05790 d7d8480d41cfc1a2f3db54b71892c0a4 379 Pfam PF10531 SLBB domain 173 220 1.5E-8 T 10-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05790 d7d8480d41cfc1a2f3db54b71892c0a4 379 Pfam PF10531 SLBB domain 256 305 9.9E-5 T 10-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05790 d7d8480d41cfc1a2f3db54b71892c0a4 379 Gene3D G3DSA:3.30.1950.10 90 164 1.9E-32 T 10-03-2017 RG49_RS05790 d7d8480d41cfc1a2f3db54b71892c0a4 379 Gene3D G3DSA:3.10.560.10 245 344 1.7E-34 T 10-03-2017 RG49_RS05790 d7d8480d41cfc1a2f3db54b71892c0a4 379 Gene3D G3DSA:1.20.5.70 345 379 4.2E-19 T 10-03-2017 RG49_RS05790 d7d8480d41cfc1a2f3db54b71892c0a4 379 Pfam PF02563 Polysaccharide biosynthesis/export protein 81 165 3.4E-27 T 10-03-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 RG49_RS05790 d7d8480d41cfc1a2f3db54b71892c0a4 379 Gene3D G3DSA:3.10.560.10 165 244 1.3E-28 T 10-03-2017 RG49_RS13750 d303538a3c8771046b84288d4297de26 237 TIGRFAM TIGR01672 AphA: HAD phosphatase, family IIIB 1 237 1.2E-127 T 10-03-2017 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00627+3.1.3.2|MetaCyc: PWY-6348 RG49_RS13750 d303538a3c8771046b84288d4297de26 237 PIRSF PIRSF017818 1 237 1.8E-123 T 10-03-2017 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00627+3.1.3.2|MetaCyc: PWY-6348 RG49_RS13750 d303538a3c8771046b84288d4297de26 237 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 11 220 5.2E-50 T 10-03-2017 IPR005519 Acid phosphatase, class B-like RG49_RS13750 d303538a3c8771046b84288d4297de26 237 Gene3D G3DSA:3.40.50.1000 31 236 4.3E-82 T 10-03-2017 IPR023214 HAD-like domain RG49_RS13750 d303538a3c8771046b84288d4297de26 237 SUPERFAMILY SSF56784 31 237 3.39E-76 T 10-03-2017 IPR023214 HAD-like domain RG49_RS20915 3efdf52fe3cd187c36223c2fe632d255 187 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 1.8E-7 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20915 3efdf52fe3cd187c36223c2fe632d255 187 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20915 3efdf52fe3cd187c36223c2fe632d255 187 PIRSF PIRSF004525 1 187 8.1E-66 T 10-03-2017 IPR016419 Prepilin peptidase-dependent protein B, predicted RG49_RS20915 3efdf52fe3cd187c36223c2fe632d255 187 Pfam PF13633 Prokaryotic N-terminal methylation site 5 30 1.8E-9 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS05570 904b57c2698f1a062f240a0717ad169d 441 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 30 437 1.6E-195 T 10-03-2017 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0042710 RG49_RS05570 904b57c2698f1a062f240a0717ad169d 441 SUPERFAMILY SSF53448 61 340 2.98E-67 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS05570 904b57c2698f1a062f240a0717ad169d 441 Pfam PF00535 Glycosyl transferase family 2 78 245 1.8E-38 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS05570 904b57c2698f1a062f240a0717ad169d 441 Gene3D G3DSA:3.90.550.10 75 321 1.5E-49 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 Gene3D G3DSA:3.40.190.10 174 264 1.4E-20 T 10-03-2017 RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 SUPERFAMILY SSF53850 89 294 7.06E-40 T 10-03-2017 RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.9E-24 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 SUPERFAMILY SSF46785 1 83 9.47E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 Pfam PF03466 LysR substrate binding domain 88 291 1.4E-43 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 Gene3D G3DSA:1.10.10.10 1 85 1.4E-30 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22385 de66fefae2695402d2b9a57258e15605 296 Gene3D G3DSA:3.40.190.10 91 173 1.5E-25 T 10-03-2017 RG49_RS19765 f462ced71b96ba4ecec883716611ad36 95 Pfam PF11115 Protein of unknown function (DUF2623) 1 92 6.2E-48 T 10-03-2017 IPR022574 Protein of unknown function DUF2623 RG49_RS19765 f462ced71b96ba4ecec883716611ad36 95 ProDom PD065638 YGHW CYTOPLASMIC STY3323 1 95 1.0E-51 T 10-03-2017 IPR022574 Protein of unknown function DUF2623 RG49_RS23810 e1dd4a22874a624b58f73c7082e2f0ca 550 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 4 237 1.3E-56 T 10-03-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 RG49_RS23810 e1dd4a22874a624b58f73c7082e2f0ca 550 Hamap MF_01165 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase [arnT]. 1 550 42.581 T 10-03-2017 IPR022839 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase GO:0016763 RG49_RS18025 d44845a02f8ee59d1e9b327b0534f8f6 110 Pfam PF00237 Ribosomal protein L22p/L17e 8 107 7.3E-34 T 10-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 RG49_RS18025 d44845a02f8ee59d1e9b327b0534f8f6 110 Gene3D G3DSA:3.90.470.10 1 109 3.1E-43 T 10-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 RG49_RS18025 d44845a02f8ee59d1e9b327b0534f8f6 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 10-03-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18025 d44845a02f8ee59d1e9b327b0534f8f6 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 4.1E-51 T 10-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18025 d44845a02f8ee59d1e9b327b0534f8f6 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.067 T 10-03-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18025 d44845a02f8ee59d1e9b327b0534f8f6 110 SUPERFAMILY SSF54843 1 109 4.06E-43 T 10-03-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 RG49_RS04500 da11db16b90d0c9b98b9deb569040ab4 463 Gene3D G3DSA:1.20.1250.20 252 457 1.4E-11 T 10-03-2017 RG49_RS04500 da11db16b90d0c9b98b9deb569040ab4 463 TIGRFAM TIGR00886 2A0108: nitrite transporter 36 418 1.1E-118 T 10-03-2017 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 RG49_RS04500 da11db16b90d0c9b98b9deb569040ab4 463 Gene3D G3DSA:1.20.1250.20 31 232 1.2E-13 T 10-03-2017 RG49_RS04500 da11db16b90d0c9b98b9deb569040ab4 463 Pfam PF07690 Major Facilitator Superfamily 45 422 3.8E-15 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS04500 da11db16b90d0c9b98b9deb569040ab4 463 SUPERFAMILY SSF103473 20 460 3.53E-36 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS20120 8aaa1ae42d0eef8631f3e60598bb4e9d 96 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 10 81 4.7E-25 T 10-03-2017 IPR003746 Protein of unknown function DUF167 RG49_RS20120 8aaa1ae42d0eef8631f3e60598bb4e9d 96 Gene3D G3DSA:3.30.1200.10 2 91 1.2E-30 T 10-03-2017 IPR003746 Protein of unknown function DUF167 RG49_RS20120 8aaa1ae42d0eef8631f3e60598bb4e9d 96 SMART SM01152 7 83 2.3E-37 T 10-03-2017 IPR003746 Protein of unknown function DUF167 RG49_RS20120 8aaa1ae42d0eef8631f3e60598bb4e9d 96 SUPERFAMILY SSF69786 2 95 1.44E-32 T 10-03-2017 IPR003746 Protein of unknown function DUF167 RG49_RS20120 8aaa1ae42d0eef8631f3e60598bb4e9d 96 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 93 20.455 T 10-03-2017 IPR003746 Protein of unknown function DUF167 RG49_RS20120 8aaa1ae42d0eef8631f3e60598bb4e9d 96 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 4 91 3.4E-35 T 10-03-2017 IPR005228 Conserved hypothetical protein CHP00251 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 630 3.2E-123 T 10-03-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.9E-60 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 1.9E-60 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.9E-60 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 1.9E-60 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 1.9E-60 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 1.9E-60 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 624 637 1.9E-60 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 Pfam PF01578 Cytochrome C assembly protein 89 296 7.0E-55 T 10-03-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 4.5E-96 T 10-03-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24160 18316fe1e7264d96be57ce14eba0d60e 647 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 634 0.0 T 10-03-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS16645 ac9334dc5ec3548c77219a8c32c166ac 200 Gene3D G3DSA:3.40.50.2300 143 192 1.2E-9 T 10-03-2017 RG49_RS16645 ac9334dc5ec3548c77219a8c32c166ac 200 Gene3D G3DSA:3.40.50.2300 25 142 4.8E-36 T 10-03-2017 RG49_RS16645 ac9334dc5ec3548c77219a8c32c166ac 200 Pfam PF13407 Periplasmic binding protein domain 38 188 7.2E-37 T 10-03-2017 IPR025997 Periplasmic binding protein RG49_RS16645 ac9334dc5ec3548c77219a8c32c166ac 200 SUPERFAMILY SSF53822 24 191 9.11E-42 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS18370 8cc445bae9769447a19025001577e868 367 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 284 6.8E-127 T 10-03-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 RG49_RS18370 8cc445bae9769447a19025001577e868 367 Pfam PF04085 rod shape-determining protein MreC 123 269 4.8E-36 T 10-03-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 RG49_RS01390 af8209e2a3430a40d861afcf35d05ad3 309 Gene3D G3DSA:3.40.1190.20 35 305 5.6E-75 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS01390 af8209e2a3430a40d861afcf35d05ad3 309 Pfam PF00294 pfkB family carbohydrate kinase 12 296 2.9E-65 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS01390 af8209e2a3430a40d861afcf35d05ad3 309 SUPERFAMILY SSF53613 4 297 1.04E-63 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS01390 af8209e2a3430a40d861afcf35d05ad3 309 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 4 305 5.9E-96 T 10-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 RG49_RS01390 af8209e2a3430a40d861afcf35d05ad3 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS01390 af8209e2a3430a40d861afcf35d05ad3 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS01390 af8209e2a3430a40d861afcf35d05ad3 309 PIRSF PIRSF000535 1 309 5.7E-111 T 10-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 RG49_RS20495 c6c906e0909d680b1efc94d9b2b6c727 466 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 363 383 - T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS20495 c6c906e0909d680b1efc94d9b2b6c727 466 Pfam PF00860 Permease family 22 415 5.0E-109 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS20495 c6c906e0909d680b1efc94d9b2b6c727 466 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 18 445 4.9E-137 T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS12315 d7e444dd7447211f42cf0dca32bc36e4 383 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 40 383 3.4E-84 T 10-03-2017 IPR010327 FldB/FldC dehydratase alpha/beta subunit RG49_RS09180 5bd66d039b799dede35975779b8160ed 225 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 5 223 3.0E-123 T 10-03-2017 IPR010843 Uncharacterised protein family AroM RG49_RS09180 5bd66d039b799dede35975779b8160ed 225 Pfam PF07302 AroM protein 5 224 5.9E-71 T 10-03-2017 IPR010843 Uncharacterised protein family AroM RG49_RS03240 ba9031b48a2a90eb766f9e8f2cfe331f 404 TIGRFAM TIGR00843 benE: benzoate transporter 1 395 1.3E-218 T 10-03-2017 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 RG49_RS03240 ba9031b48a2a90eb766f9e8f2cfe331f 404 Pfam PF03594 Benzoate membrane transport protein 19 394 9.7E-155 T 10-03-2017 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 RG49_RS14075 f98a58f47a72c930b718f4f929f7f8fa 141 Pfam PF13801 Heavy-metal resistance 9 120 7.1E-21 T 10-03-2017 IPR025961 Heavy-metal resistance protein RG49_RS14075 f98a58f47a72c930b718f4f929f7f8fa 141 ProDom PD097062 ZINC RESISTANCE-ASSOCIATED PERIPLASMIC PRECURSOR SIGNAL YJAI SEQUENCING DIRECT DFFA 1 119 2.0E-56 T 10-03-2017 IPR020365 Zinc resistance-associated protein, ZraP GO:0008270|GO:0042597 RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 SUPERFAMILY SSF55073 243 397 1.73E-44 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 SMART SM00052 405 649 6.7E-119 T 10-03-2017 IPR001633 EAL domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 Gene3D G3DSA:3.30.450.20 111 218 9.9E-18 T 10-03-2017 RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 Pfam PF00563 EAL domain 412 644 6.4E-65 T 10-03-2017 IPR001633 EAL domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 SUPERFAMILY SSF55785 123 234 6.12E-15 T 10-03-2017 IPR000014 PAS domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 Gene3D G3DSA:3.20.20.450 409 656 4.9E-87 T 10-03-2017 IPR001633 EAL domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 Gene3D G3DSA:3.30.70.270 239 403 9.7E-52 T 10-03-2017 RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 235 394 7.1E-35 T 10-03-2017 IPR000160 GGDEF domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 Pfam PF13426 PAS domain 123 225 4.7E-9 T 10-03-2017 IPR000014 PAS domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 SMART SM00267 226 395 8.2E-70 T 10-03-2017 IPR000160 GGDEF domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 SUPERFAMILY SSF141868 412 657 1.83E-81 T 10-03-2017 IPR001633 EAL domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 390 2.3E-46 T 10-03-2017 IPR000160 GGDEF domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 115 233 2.3E-12 T 10-03-2017 IPR000014 PAS domain RG49_RS04130 8f65242958e6ed927ac8030fe50f5c35 661 SMART SM00091 111 177 1.0E-6 T 10-03-2017 IPR000014 PAS domain RG49_RS14080 d186d46ea1a0898f3498b972c059c970 231 Pfam PF08139 Prokaryotic membrane lipoprotein lipid attachment site 6 33 3.4E-8 T 10-03-2017 IPR012640 Membrane lipoprotein, lipid attachment site RG49_RS14080 d186d46ea1a0898f3498b972c059c970 231 PIRSF PIRSF006993 1 231 1.4E-117 T 10-03-2017 IPR016500 Uncharacterised conserved protein UCP006993 RG49_RS14080 d186d46ea1a0898f3498b972c059c970 231 Pfam PF07356 Protein of unknown function (DUF1481) 42 227 5.8E-69 T 10-03-2017 IPR010858 Protein of unknown function DUF1481 RG49_RS14955 65d5288c2db8222ece4e8f0eb59d4d79 443 SUPERFAMILY SSF55920 163 438 1.83E-57 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS14955 65d5288c2db8222ece4e8f0eb59d4d79 443 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 335 347 - T 10-03-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site RG49_RS14955 65d5288c2db8222ece4e8f0eb59d4d79 443 Hamap MF_01279 Xaa-Pro dipeptidase [pepQ]. 1 443 58.546 T 10-03-2017 IPR022846 Xaa-Pro dipeptidase GO:0016795 RG49_RS14955 65d5288c2db8222ece4e8f0eb59d4d79 443 Pfam PF00557 Metallopeptidase family M24 168 430 3.2E-47 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS14955 65d5288c2db8222ece4e8f0eb59d4d79 443 Gene3D G3DSA:3.90.230.10 161 439 3.2E-56 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS16980 df9b74708cc1a3803391984b0597a232 175 SUPERFAMILY SSF46894 111 169 1.33E-7 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS16980 df9b74708cc1a3803391984b0597a232 175 Gene3D G3DSA:3.20.20.150 21 71 1.5E-10 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS16980 df9b74708cc1a3803391984b0597a232 175 Gene3D G3DSA:1.10.10.10 108 169 2.0E-7 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16980 df9b74708cc1a3803391984b0597a232 175 Pfam PF00196 Bacterial regulatory proteins, luxR family 117 167 1.3E-5 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS01805 1ee330c0c62fe11a881a261ea0306b06 125 Pfam PF06945 Protein of unknown function (DUF1289) 58 103 5.9E-19 T 10-03-2017 IPR010710 Protein of unknown function DUF1289 RG49_RS07675 0782f6f252c33425908184b0f367952b 97 SUPERFAMILY SSF47598 51 86 5.78E-5 T 10-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 RG49_RS07675 0782f6f252c33425908184b0f367952b 97 Pfam PF01402 Ribbon-helix-helix protein, copG family 52 88 4.7E-10 T 10-03-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 14 205 7.2E-112 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 103 114 - T 10-03-2017 IPR018215 ClpP, Ser active site RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 SUPERFAMILY SSF52096 23 206 1.77E-75 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 16 206 44.936 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 Gene3D G3DSA:3.90.226.10 16 205 7.0E-91 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 Pfam PF00574 Clp protease 25 205 5.2E-89 T 10-03-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 PRINTS PR00127 Clp protease catalytic subunit P signature 124 143 2.2E-54 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 PRINTS PR00127 Clp protease catalytic subunit P signature 181 200 2.2E-54 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 PRINTS PR00127 Clp protease catalytic subunit P signature 32 47 2.2E-54 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 PRINTS PR00127 Clp protease catalytic subunit P signature 103 120 2.2E-54 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 PRINTS PR00127 Clp protease catalytic subunit P signature 72 92 2.2E-54 T 10-03-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 RG49_RS08935 c80cda9efd4d78c152403bd0ab9e6143 207 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 125 138 - T 10-03-2017 IPR033135 ClpP, histidine active site RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF04539 Sigma-70 region 3 174 248 1.2E-20 T 10-03-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF04542 Sigma-70 region 2 94 163 3.3E-21 T 10-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 266 278 2.5E-27 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 287 302 2.5E-27 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 118 131 2.5E-27 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 302 313 2.5E-27 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 142 150 2.5E-27 T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 SUPERFAMILY SSF88946 56 164 2.75E-45 T 10-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 3 328 40.0 T 10-03-2017 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Gene3D G3DSA:1.10.10.10 167 216 2.3E-15 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 287 313 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 48 328 4.4E-145 T 10-03-2017 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Gene3D G3DSA:1.10.10.10 257 322 2.4E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 118 131 - T 10-03-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF00140 Sigma-70 factor, region 1.2 56 88 3.0E-11 T 10-03-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 SUPERFAMILY SSF88659 225 323 1.46E-23 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Gene3D G3DSA:1.10.601.10 50 163 9.6E-55 T 10-03-2017 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF04545 Sigma-70, region 4 262 315 1.8E-15 T 10-03-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 SUPERFAMILY SSF88659 167 241 8.72E-15 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS21365 58216af11ca71371bf7a8801dbe9637f 330 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 90 317 5.5E-35 T 10-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 Gene3D G3DSA:3.50.50.60 254 415 6.4E-22 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 Gene3D G3DSA:3.50.50.60 1 53 6.4E-22 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 TIGRFAM TIGR03378 glycerol3P_GlpB: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit 3 411 1.9E-177 T 10-03-2017 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 SUPERFAMILY SSF51905 249 416 2.29E-20 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 SUPERFAMILY SSF51905 195 210 2.29E-20 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 SUPERFAMILY SSF51905 160 166 2.29E-20 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 SUPERFAMILY SSF51905 1 35 2.29E-20 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 Hamap MF_00753 Anaerobic glycerol-3-phosphate dehydrogenase subunit B [glpB]. 1 415 50.061 T 10-03-2017 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 PIRSF PIRSF000141 1 418 2.7E-172 T 10-03-2017 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 RG49_RS23890 a4f456db1f3984264180d0e626155bd5 419 Pfam PF00890 FAD binding domain 4 399 5.9E-61 T 10-03-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS00245 f5a5393085ab47d17284d4beadca7051 401 Pfam PF04143 Sulphur transport 3 160 4.1E-26 T 10-03-2017 IPR007272 Sulphur transport domain RG49_RS00245 f5a5393085ab47d17284d4beadca7051 401 Pfam PF04143 Sulphur transport 237 393 2.5E-24 T 10-03-2017 IPR007272 Sulphur transport domain RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 Hamap MF_01201 Alanine racemase. 2 356 33.77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 TIGRFAM TIGR00492 alr: alanine racemase 4 356 1.4E-141 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 SUPERFAMILY SSF51419 9 233 2.62E-64 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 Pfam PF00842 Alanine racemase, C-terminal domain 232 354 4.0E-37 T 10-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 61 79 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 190 217 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 27 43 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 248 263 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 286 303 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 338 351 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 265 280 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 155 166 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 PRINTS PR00992 Alanine racemase signature 121 133 4.7E-77 T 10-03-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 Pfam PF01168 Alanine racemase, N-terminal domain 9 217 9.3E-67 T 10-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 Gene3D G3DSA:3.20.20.10 11 207 4.9E-67 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 SUPERFAMILY SSF50621 227 355 1.01E-44 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 Gene3D G3DSA:2.40.37.10 208 355 8.9E-55 T 10-03-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 SMART SM01005 232 356 6.6E-62 T 10-03-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS04710 60ada618773dd222501819dd61cddfc7 356 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 10-03-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 Gene3D G3DSA:1.10.40.60 107 211 2.5E-40 T 10-03-2017 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 Gene3D G3DSA:3.30.1300.30 28 106 2.6E-27 T 10-03-2017 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 Gene3D G3DSA:3.30.1300.30 212 325 7.2E-32 T 10-03-2017 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 SUPERFAMILY SSF158544 103 211 1.33E-31 T 10-03-2017 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 SUPERFAMILY SSF54523 39 102 2.98E-18 T 10-03-2017 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 SUPERFAMILY SSF158544 214 282 2.62E-18 T 10-03-2017 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 PIRSF PIRSF002786 4 325 1.6E-67 T 10-03-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 RG49_RS20025 26594de604f76216e22dba7fd3e6226a 325 Pfam PF03934 Type II secretion system (T2SS), protein K 32 312 5.6E-85 T 10-03-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 RG49_RS22760 c431ab61e0ddc8579810ce6d355caa2d 190 Pfam PF13740 ACT domain 7 82 5.0E-26 T 10-03-2017 RG49_RS22760 c431ab61e0ddc8579810ce6d355caa2d 190 Gene3D G3DSA:3.30.70.260 6 84 2.2E-32 T 10-03-2017 RG49_RS22760 c431ab61e0ddc8579810ce6d355caa2d 190 SUPERFAMILY SSF55021 91 179 1.53E-17 T 10-03-2017 RG49_RS22760 c431ab61e0ddc8579810ce6d355caa2d 190 Gene3D G3DSA:3.30.70.260 92 188 4.2E-46 T 10-03-2017 RG49_RS22760 c431ab61e0ddc8579810ce6d355caa2d 190 SUPERFAMILY SSF55021 6 88 9.99E-17 T 10-03-2017 RG49_RS22760 c431ab61e0ddc8579810ce6d355caa2d 190 PIRSF PIRSF028103 5 180 1.2E-72 T 10-03-2017 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 RG49_RS22760 c431ab61e0ddc8579810ce6d355caa2d 190 Pfam PF01842 ACT domain 97 166 3.9E-7 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS16805 5156e2693333cb24f42b9d8757472f75 423 Pfam PF03222 Tryptophan/tyrosine permease family 21 404 1.2E-5 T 10-03-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 RG49_RS03210 df3b5056d744635fb7de4674fb8adb8d 468 Pfam PF00155 Aminotransferase class I and II 145 445 1.0E-31 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS03210 df3b5056d744635fb7de4674fb8adb8d 468 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 2.4E-14 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS03210 df3b5056d744635fb7de4674fb8adb8d 468 SUPERFAMILY SSF53383 91 466 1.17E-92 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS03210 df3b5056d744635fb7de4674fb8adb8d 468 Gene3D G3DSA:3.40.640.10 144 356 2.4E-70 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS03210 df3b5056d744635fb7de4674fb8adb8d 468 SMART SM00345 7 66 1.9E-15 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS03210 df3b5056d744635fb7de4674fb8adb8d 468 Gene3D G3DSA:1.10.10.10 1 67 1.5E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03210 df3b5056d744635fb7de4674fb8adb8d 468 SUPERFAMILY SSF46785 2 70 3.84E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13500 acec23e06d0eadaa2f226b0994eca9cb 226 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS13500 acec23e06d0eadaa2f226b0994eca9cb 226 Pfam PF00005 ABC transporter 24 178 3.4E-29 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS13500 acec23e06d0eadaa2f226b0994eca9cb 226 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 1 218 8.0E-112 T 10-03-2017 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 RG49_RS13500 acec23e06d0eadaa2f226b0994eca9cb 226 SUPERFAMILY SSF52540 2 223 2.21E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13500 acec23e06d0eadaa2f226b0994eca9cb 226 SMART SM00382 33 226 2.5E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS13500 acec23e06d0eadaa2f226b0994eca9cb 226 Gene3D G3DSA:3.40.50.300 1 222 4.9E-50 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS25120 62f87881f58f77a8358f450a95407e24 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 56 1.4E-13 T 10-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM RG49_RS25120 62f87881f58f77a8358f450a95407e24 83 SUPERFAMILY SSF143120 1 81 1.26E-26 T 10-03-2017 RG49_RS25120 62f87881f58f77a8358f450a95407e24 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 73 2.8E-25 T 10-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM RG49_RS25120 62f87881f58f77a8358f450a95407e24 83 Gene3D G3DSA:3.40.1620.10 1 51 3.9E-11 T 10-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 Gene3D G3DSA:3.40.50.720 7 168 1.1E-38 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 Gene3D G3DSA:1.10.1040.10 172 293 5.0E-45 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 SUPERFAMILY SSF51735 8 168 7.69E-31 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 172 291 7.7E-35 T 10-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 PIRSF PIRSF000103 1 296 1.1E-57 T 10-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 166 3.1E-35 T 10-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 11 24 - T 10-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS21390 7e3407cf8a4cdbc0f3bbebfdd3efa8f3 302 SUPERFAMILY SSF48179 170 294 1.25E-37 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS06600 215309d116654603b4293c2a7bf1c9f3 516 Pfam PF12571 Phage tail-collar fibre protein 1 150 2.9E-63 T 10-03-2017 IPR022225 Phage tail fibre protein RG49_RS06600 215309d116654603b4293c2a7bf1c9f3 516 Pfam PF07484 Phage Tail Collar Domain 361 408 4.9E-14 T 10-03-2017 IPR011083 Phage tail collar domain RG49_RS06600 215309d116654603b4293c2a7bf1c9f3 516 Gene3D G3DSA:3.90.1340.10 356 413 2.6E-14 T 10-03-2017 IPR011083 Phage tail collar domain RG49_RS06600 215309d116654603b4293c2a7bf1c9f3 516 SUPERFAMILY SSF88874 350 515 2.49E-42 T 10-03-2017 RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1181 1258 7.9E-24 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF03527 RHS protein 1155 1190 5.1E-15 T 10-03-2017 IPR001826 RHS protein RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 SUPERFAMILY SSF69304 454 667 8.76E-6 T 10-03-2017 RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 579 619 7.4E-12 T 10-03-2017 IPR006530 YD repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 641 681 7.2E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 540 572 6.6E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 455 487 0.002 T 10-03-2017 IPR006530 YD repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 493 518 2.1E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 600 631 5.5E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 413 448 4.1E-7 T 10-03-2017 IPR006530 YD repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF05593 RHS Repeat 539 572 1.2E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF05593 RHS Repeat 621 656 6.9E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF05593 RHS Repeat 413 444 8.7E-7 T 10-03-2017 IPR031325 RHS repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF05593 RHS Repeat 579 615 1.7E-10 T 10-03-2017 IPR031325 RHS repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF05593 RHS Repeat 493 532 1.2E-4 T 10-03-2017 IPR031325 RHS repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF05593 RHS Repeat 320 357 5.1E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 PRINTS PR00394 RHS protein signature 1226 1245 4.4E-53 T 10-03-2017 IPR001826 RHS protein RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 PRINTS PR00394 RHS protein signature 1148 1168 4.4E-53 T 10-03-2017 IPR001826 RHS protein RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 PRINTS PR00394 RHS protein signature 1179 1194 4.4E-53 T 10-03-2017 IPR001826 RHS protein RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 PRINTS PR00394 RHS protein signature 1203 1223 4.4E-53 T 10-03-2017 IPR001826 RHS protein RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 PRINTS PR00394 RHS protein signature 1110 1129 4.4E-53 T 10-03-2017 IPR001826 RHS protein RG49_RS08585 c055766282080f629bf660ed5f39dca2 1426 Pfam PF14220 Domain of unknown function (DUF4329) 1292 1411 5.5E-31 T 10-03-2017 IPR025479 Domain of unknown function DUF4329 RG49_RS07055 609a06ed01466289e7bfc20a0a1fd990 332 SUPERFAMILY SSF111369 177 324 4.84E-13 T 10-03-2017 RG49_RS07055 609a06ed01466289e7bfc20a0a1fd990 332 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 319 4.4E-18 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS07055 609a06ed01466289e7bfc20a0a1fd990 332 SUPERFAMILY SSF111369 113 170 1.96E-5 T 10-03-2017 RG49_RS07055 609a06ed01466289e7bfc20a0a1fd990 332 Hamap MF_01304 UPF0194 membrane protein YbhG [ybhG]. 2 328 50.673 T 10-03-2017 IPR022936 Uncharacterised protein family UPF0194, membrane protein YbhG RG49_RS07055 609a06ed01466289e7bfc20a0a1fd990 332 Gene3D G3DSA:2.40.50.100 44 77 2.7E-13 T 10-03-2017 RG49_RS07055 609a06ed01466289e7bfc20a0a1fd990 332 Gene3D G3DSA:2.40.50.100 204 235 2.7E-13 T 10-03-2017 RG49_RS07055 609a06ed01466289e7bfc20a0a1fd990 332 SUPERFAMILY SSF111369 42 99 8.89E-9 T 10-03-2017 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 SUPERFAMILY SSF55021 79 162 6.26E-25 T 10-03-2017 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 6.0E-37 T 10-03-2017 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 Pfam PF10369 Small subunit of acetolactate synthase 84 158 5.9E-23 T 10-03-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 SUPERFAMILY SSF55021 2 74 2.34E-22 T 10-03-2017 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 Pfam PF13710 ACT domain 12 73 2.7E-15 T 10-03-2017 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 159 1.5E-68 T 10-03-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 Gene3D G3DSA:3.30.70.260 1 76 8.3E-36 T 10-03-2017 RG49_RS11470 20c9b2c99325f00f97eca293da032b3f 163 Gene3D G3DSA:3.30.70.1150 83 162 6.9E-27 T 10-03-2017 RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 Gene3D G3DSA:3.40.30.10 452 561 1.0E-37 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 SUPERFAMILY SSF74863 27 141 6.15E-42 T 10-03-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 Pfam PF13899 Thioredoxin-like 462 536 1.5E-12 T 10-03-2017 RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 564 40.759 T 10-03-2017 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 ProSitePatterns PS00194 Thioredoxin family active site. 472 490 - T 10-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 SUPERFAMILY SSF52833 444 561 6.77E-25 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 Pfam PF11412 Disulphide bond corrector protein DsbC 28 138 9.4E-36 T 10-03-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 171 376 1.1E-18 T 10-03-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 RG49_RS13250 1cc2b33a587a076b516310fb2c6221c5 565 Gene3D G3DSA:2.60.40.1250 24 142 1.0E-47 T 10-03-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain RG49_RS01485 8a242f95bb6b2e7f0f740e9ec19d8801 237 Pfam PF00563 EAL domain 13 222 1.5E-8 T 10-03-2017 IPR001633 EAL domain RG49_RS01485 8a242f95bb6b2e7f0f740e9ec19d8801 237 SUPERFAMILY SSF141868 13 230 3.79E-11 T 10-03-2017 IPR001633 EAL domain RG49_RS01485 8a242f95bb6b2e7f0f740e9ec19d8801 237 Gene3D G3DSA:3.20.20.450 13 236 1.7E-7 T 10-03-2017 IPR001633 EAL domain RG49_RS19080 3aec5cc31bfb0c03fab825265b99b896 174 Pfam PF03614 Repressor of phase-1 flagellin 3 167 2.1E-63 T 10-03-2017 IPR003223 Flagellin phase1 repressor GO:0003700|GO:0006355 RG49_RS19080 3aec5cc31bfb0c03fab825265b99b896 174 ProDom PD016683 REPRESSOR TRANSCRIPTION FLIC PLASMID PHASE FLAGELLIN TRANSCRIPTIONAL DNA-BINDING GENE FLAGELLUM 1 174 1.0E-97 T 10-03-2017 IPR003223 Flagellin phase1 repressor GO:0003700|GO:0006355 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 Gene3D G3DSA:3.30.70.20 104 137 2.1E-11 T 10-03-2017 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 Gene3D G3DSA:3.30.70.20 138 172 6.6E-15 T 10-03-2017 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 SUPERFAMILY SSF54862 28 271 6.38E-72 T 10-03-2017 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 Gene3D G3DSA:1.20.5.480 247 294 1.9E-26 T 10-03-2017 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 PIRSF PIRSF036298 1 300 7.1E-166 T 10-03-2017 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 289 1.3E-144 T 10-03-2017 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 Gene3D G3DSA:3.30.70.20 30 103 8.5E-37 T 10-03-2017 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 Gene3D G3DSA:3.30.70.20 173 227 8.5E-37 T 10-03-2017 RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 288 4.3E-21 T 10-03-2017 IPR015246 Formate dehydrogenase, transmembrane RG49_RS14700 e5a904638cb9b4a8bcc407cc8b46856c 300 Pfam PF13247 4Fe-4S dicluster domain 92 188 8.3E-25 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS00570 10bf2b136d7e76cf4539f28f5a1cddd6 131 Pfam PF01124 MAPEG family 3 120 1.5E-26 T 10-03-2017 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein RG49_RS00570 10bf2b136d7e76cf4539f28f5a1cddd6 131 SUPERFAMILY SSF161084 4 127 4.97E-31 T 10-03-2017 RG49_RS00570 10bf2b136d7e76cf4539f28f5a1cddd6 131 Gene3D G3DSA:1.20.120.550 4 127 4.1E-23 T 10-03-2017 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain RG49_RS19680 6785684b497f6352952536f341ce094f 85 SUPERFAMILY SSF58042 24 72 2.88E-18 T 10-03-2017 RG49_RS19680 6785684b497f6352952536f341ce094f 85 Gene3D G3DSA:1.20.5.190 24 69 1.9E-6 T 10-03-2017 RG49_RS19680 6785684b497f6352952536f341ce094f 85 PIRSF PIRSF002855 1 82 9.8E-26 T 10-03-2017 IPR016367 Murein-lipoprotein RG49_RS19680 6785684b497f6352952536f341ce094f 85 Pfam PF04728 Lipoprotein leucine-zipper 25 71 2.7E-13 T 10-03-2017 IPR006817 Lipoprotein leucine-zipper GO:0019867 RG49_RS23315 ecbace18cdea7d5b5405af802745a0ff 512 SUPERFAMILY SSF103473 479 504 1.44E-68 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23315 ecbace18cdea7d5b5405af802745a0ff 512 SUPERFAMILY SSF103473 255 427 1.44E-68 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23315 ecbace18cdea7d5b5405af802745a0ff 512 SUPERFAMILY SSF103473 7 197 1.44E-68 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23315 ecbace18cdea7d5b5405af802745a0ff 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 502 6.8E-171 T 10-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 RG49_RS23315 ecbace18cdea7d5b5405af802745a0ff 512 Gene3D G3DSA:1.20.1250.20 17 198 1.1E-31 T 10-03-2017 RG49_RS23315 ecbace18cdea7d5b5405af802745a0ff 512 Pfam PF07690 Major Facilitator Superfamily 23 417 1.1E-51 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS23315 ecbace18cdea7d5b5405af802745a0ff 512 Gene3D G3DSA:1.20.1250.20 270 505 1.6E-17 T 10-03-2017 RG49_RS01130 9da7945b21f0ece6c78c43720a9a4a7b 326 SUPERFAMILY SSF51430 1 320 7.2E-86 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS01130 9da7945b21f0ece6c78c43720a9a4a7b 326 Gene3D G3DSA:3.20.20.100 1 321 3.9E-88 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS01130 9da7945b21f0ece6c78c43720a9a4a7b 326 PRINTS PR00069 Aldo-keto reductase signature 154 171 1.6E-9 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01130 9da7945b21f0ece6c78c43720a9a4a7b 326 PRINTS PR00069 Aldo-keto reductase signature 188 217 1.6E-9 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01130 9da7945b21f0ece6c78c43720a9a4a7b 326 PRINTS PR00069 Aldo-keto reductase signature 120 138 1.6E-9 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01130 9da7945b21f0ece6c78c43720a9a4a7b 326 Pfam PF00248 Aldo/keto reductase family 15 320 5.6E-64 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS04795 9d5029004b702bc54723daa4db8308a8 270 PIRSF PIRSF003092 1 270 3.6E-100 T 10-03-2017 IPR025501 ATP binding protein MinD RG49_RS04795 9d5029004b702bc54723daa4db8308a8 270 SUPERFAMILY SSF52540 1 268 2.75E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04795 9d5029004b702bc54723daa4db8308a8 270 Gene3D G3DSA:3.40.50.300 1 248 1.5E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04795 9d5029004b702bc54723daa4db8308a8 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 1.3E-110 T 10-03-2017 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 RG49_RS04795 9d5029004b702bc54723daa4db8308a8 270 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 217 3.1E-28 T 10-03-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain RG49_RS13825 e4d26b48161240273455ecf80e7e407a 807 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 13 807 34.014 T 10-03-2017 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 RG49_RS13825 e4d26b48161240273455ecf80e7e407a 807 SMART SM00563 300 427 1.1E-27 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS13825 e4d26b48161240273455ecf80e7e407a 807 PIRSF PIRSF000437 19 807 0.0 T 10-03-2017 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 RG49_RS13825 e4d26b48161240273455ecf80e7e407a 807 PIRSF PIRSF500064 2 807 0.0 T 10-03-2017 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 RG49_RS13825 e4d26b48161240273455ecf80e7e407a 807 Pfam PF01553 Acyltransferase 282 424 4.4E-26 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS13825 e4d26b48161240273455ecf80e7e407a 807 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 11 799 0.0 T 10-03-2017 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 RG49_RS13825 e4d26b48161240273455ecf80e7e407a 807 SUPERFAMILY SSF69593 245 482 3.66E-23 T 10-03-2017 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 Pfam PF01842 ACT domain 323 378 2.1E-6 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 449 4.2E-154 T 10-03-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 PIRSF PIRSF000726 2 449 4.8E-168 T 10-03-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 10-03-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 Pfam PF00696 Amino acid kinase family 4 277 3.0E-47 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 SUPERFAMILY SSF55021 297 393 5.56E-17 T 10-03-2017 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 6.5E-140 T 10-03-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 SUPERFAMILY SSF55021 372 448 4.81E-14 T 10-03-2017 RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 SUPERFAMILY SSF53633 4 292 3.93E-76 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 Gene3D G3DSA:3.40.1160.10 3 53 3.3E-60 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS13945 10ae47177bcf8044fdf2f4ed94c3bcbc 449 Gene3D G3DSA:3.40.1160.10 106 294 3.3E-60 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 7 23 3.5E-17 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 28 42 3.5E-17 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 173 185 3.5E-17 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 47 60 3.5E-17 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 PIRSF PIRSF000398 1 264 3.8E-61 T 10-03-2017 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 SUPERFAMILY SSF53335 2 260 6.98E-70 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 176 182 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 Gene3D G3DSA:1.10.1020.10 57 154 6.0E-33 T 10-03-2017 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 Gene3D G3DSA:3.40.50.150 158 260 4.2E-48 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 Gene3D G3DSA:3.40.50.150 1 56 4.2E-48 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 TIGRFAM TIGR00571 dam: DNA adenine methylase 1 260 5.8E-96 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS06725 26890792258ac862ebec7fa0a9df4439 285 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 7 244 4.3E-73 T 10-03-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 RG49_RS20035 f0c181abf863ce639abb61b92fa14a8b 178 Gene3D G3DSA:3.30.1360.100 101 178 1.4E-31 T 10-03-2017 IPR023229 Type II secretion system protein M, periplasmic domain RG49_RS20035 f0c181abf863ce639abb61b92fa14a8b 178 SUPERFAMILY SSF103054 102 177 3.01E-20 T 10-03-2017 IPR023229 Type II secretion system protein M, periplasmic domain RG49_RS20035 f0c181abf863ce639abb61b92fa14a8b 178 Pfam PF04612 Type II secretion system (T2SS), protein M 24 177 2.5E-41 T 10-03-2017 IPR007690 Type II secretion system, protein M GO:0006858 RG49_RS20035 f0c181abf863ce639abb61b92fa14a8b 178 PIRSF PIRSF006291 20 177 5.8E-30 T 10-03-2017 IPR007690 Type II secretion system, protein M GO:0006858 RG49_RS19710 41cd95fed8352133b976830ca3ed6a6f 219 Pfam PF09335 SNARE associated Golgi protein 48 173 9.5E-19 T 10-03-2017 IPR032816 SNARE associated Golgi protein RG49_RS24930 be17a11426849b2730a8809d02c5cb3f 159 SUPERFAMILY SSF55811 2 152 6.09E-34 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS24930 be17a11426849b2730a8809d02c5cb3f 159 Pfam PF00293 NUDIX domain 22 142 2.0E-19 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS24930 be17a11426849b2730a8809d02c5cb3f 159 Gene3D G3DSA:3.90.79.10 6 151 9.0E-36 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS24930 be17a11426849b2730a8809d02c5cb3f 159 Hamap MF_00941 GDP-mannose mannosyl hydrolase [gmm]. 1 159 52.274 T 10-03-2017 IPR028613 GDP-mannose mannosyl hydrolase, Enterobacteria GO:0000287|GO:0008727|GO:0030145 RG49_RS24930 be17a11426849b2730a8809d02c5cb3f 159 PIRSF PIRSF037599 1 152 1.5E-73 T 10-03-2017 IPR033715 GDP-mannose mannosyl hydrolase GO:0008727 RG49_RS24930 be17a11426849b2730a8809d02c5cb3f 159 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS21225 d07a0f3b6ef069a63976276551ee69c0 121 PIRSF PIRSF006113 1 121 9.8E-57 T 10-03-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 RG49_RS21225 d07a0f3b6ef069a63976276551ee69c0 121 TIGRFAM TIGR00039 6PTHBS: 6-pyruvoyl tetrahydropterin synthase/QueD family protein 4 120 1.0E-38 T 10-03-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 RG49_RS21225 d07a0f3b6ef069a63976276551ee69c0 121 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 6 97 5.6E-33 T 10-03-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 RG49_RS21225 d07a0f3b6ef069a63976276551ee69c0 121 SUPERFAMILY SSF55620 1 120 1.5E-40 T 10-03-2017 RG49_RS21225 d07a0f3b6ef069a63976276551ee69c0 121 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 7 121 7.6E-34 T 10-03-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 RG49_RS21225 d07a0f3b6ef069a63976276551ee69c0 121 Gene3D G3DSA:3.30.479.10 2 121 8.6E-40 T 10-03-2017 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 Pfam PF01116 Fructose-bisphosphate aldolase class-II 17 355 8.6E-89 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 SUPERFAMILY SSF51569 4 357 6.23E-132 T 10-03-2017 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 357 5.0E-118 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 358 6.2E-194 T 10-03-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 Gene3D G3DSA:3.20.20.70 11 355 1.1E-123 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 172 183 - T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 101 112 - T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS20265 2850d15ff93041e80764356a1cb98b51 359 PIRSF PIRSF001359 13 359 2.4E-108 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS23035 d371d2d204ff54d40970d93dbfef7c21 283 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 16 275 2.4E-52 T 10-03-2017 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS23035 d371d2d204ff54d40970d93dbfef7c21 283 Hamap MF_01638 Pyridoxine/pyridoxal/pyridoxamine kinase [pdxK]. 1 283 55.744 T 10-03-2017 IPR023479 Pyridoxine/pyridoxal/pyridoxamine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282 RG49_RS23035 d371d2d204ff54d40970d93dbfef7c21 283 Gene3D G3DSA:3.40.1190.20 18 276 2.6E-68 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS23035 d371d2d204ff54d40970d93dbfef7c21 283 SUPERFAMILY SSF53613 18 274 9.51E-60 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS23035 d371d2d204ff54d40970d93dbfef7c21 283 Pfam PF08543 Phosphomethylpyrimidine kinase 88 265 2.0E-25 T 10-03-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 RG49_RS25155 398b6bd73cc6f93dff8c3406265a0698 475 Gene3D G3DSA:3.30.420.10 2 201 4.6E-88 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS25155 398b6bd73cc6f93dff8c3406265a0698 475 SUPERFAMILY SSF53098 9 474 2.28E-136 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS25155 398b6bd73cc6f93dff8c3406265a0698 475 PIRSF PIRSF000977 3 475 8.3E-202 T 10-03-2017 IPR023607 Exodeoxyribonuclease I GO:0004529 RG49_RS25155 398b6bd73cc6f93dff8c3406265a0698 475 SMART SM00479 10 203 0.0026 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS25155 398b6bd73cc6f93dff8c3406265a0698 475 Pfam PF00929 Exonuclease 13 188 2.6E-31 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS25155 398b6bd73cc6f93dff8c3406265a0698 475 Pfam PF08411 Exonuclease C-terminal 212 472 4.1E-104 T 10-03-2017 IPR013620 Exonuclease C-terminal GO:0006281|GO:0008852 RG49_RS13160 b715da47d04f9735194c841a1b3d28d5 119 ProDom PD015693 FUMARATE MEMBRANE REDUCTASE D SUBUNIT INNER TRANSMEMBRANE HYDROPHOBIC REDUCTASE POLYPEPTIDE 1 106 8.0E-47 T 10-03-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 RG49_RS13160 b715da47d04f9735194c841a1b3d28d5 119 Pfam PF02313 Fumarate reductase subunit D 6 116 6.5E-52 T 10-03-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 RG49_RS13160 b715da47d04f9735194c841a1b3d28d5 119 SUPERFAMILY SSF81343 1 119 2.62E-53 T 10-03-2017 RG49_RS13160 b715da47d04f9735194c841a1b3d28d5 119 Gene3D G3DSA:1.20.1300.10 1 119 1.5E-55 T 10-03-2017 RG49_RS13160 b715da47d04f9735194c841a1b3d28d5 119 Hamap MF_00709 Fumarate reductase subunit D [frdD]. 2 119 27.602 T 10-03-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 RG49_RS13160 b715da47d04f9735194c841a1b3d28d5 119 PIRSF PIRSF000179 1 119 3.4E-53 T 10-03-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 249 258 4.7E-39 T 10-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 227 238 4.7E-39 T 10-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 141 4.7E-39 T 10-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 161 179 4.7E-39 T 10-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 198 215 4.7E-39 T 10-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 279 39.215 T 10-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 281 1.7E-152 T 10-03-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 Pfam PF01039 Carboxyl transferase domain 54 265 3.3E-19 T 10-03-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 SUPERFAMILY SSF52096 23 284 7.96E-92 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS23500 00f16035247d9646639b739f14fd7dc5 304 Gene3D G3DSA:3.90.226.10 17 285 1.1E-81 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 Gene3D G3DSA:3.20.20.80 7 477 3.3E-154 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 12 26 - T 10-03-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 373 381 - T 10-03-2017 IPR018120 Glycoside hydrolase family 1, active site RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 SUPERFAMILY SSF51445 4 472 1.84E-167 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 Pfam PF00232 Glycosyl hydrolase family 1 7 476 3.2E-132 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 2.1E-16 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 2.1E-16 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 2.1E-16 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 308 322 2.1E-16 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS20395 fd63217667bb10c86656a1ecf3299020 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 2.1E-16 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 23 185 6.5E-52 T 10-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 PRINTS PR00084 Mannitol dehydrogenase signature 176 189 1.6E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 PRINTS PR00084 Mannitol dehydrogenase signature 245 260 1.6E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 PRINTS PR00084 Mannitol dehydrogenase signature 215 228 1.6E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 PRINTS PR00084 Mannitol dehydrogenase signature 24 34 1.6E-21 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 SUPERFAMILY SSF48179 280 483 1.53E-66 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 SUPERFAMILY SSF51735 5 278 3.94E-94 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 Gene3D G3DSA:3.40.50.720 5 278 2.0E-111 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 213 459 8.1E-103 T 10-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 215 227 - T 10-03-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS02500 f346325b37f1992b91e3a6ebf7c20147 486 Gene3D G3DSA:1.10.1040.10 279 483 5.5E-76 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS01290 c815188862f33fcfaa642178544a99b2 295 SMART SM00465 34 112 9.3E-16 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS01290 c815188862f33fcfaa642178544a99b2 295 SUPERFAMILY SSF82771 34 111 1.44E-10 T 10-03-2017 IPR000305 GIY-YIG nuclease superfamily RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 SUPERFAMILY SSF55315 103 179 3.3E-10 T 10-03-2017 IPR029064 50S ribosomal protein L30e-like RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 Gene3D G3DSA:3.30.1330.30 102 178 6.3E-9 T 10-03-2017 IPR029064 50S ribosomal protein L30e-like RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 Pfam PF00588 SpoU rRNA Methylase family 199 336 6.5E-28 T 10-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 SMART SM00967 109 184 7.4E-9 T 10-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 110 181 1.4E-12 T 10-03-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 SUPERFAMILY SSF75217 185 343 6.8E-36 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 PIRSF PIRSF006280 1 345 1.9E-176 T 10-03-2017 IPR016479 tRNA/rRNA methyltransferase, YfiF, predicted GO:0008168 RG49_RS22130 0daba42f9cb1b20c55ca742c40e802af 345 Gene3D G3DSA:3.40.1280.10 191 343 4.8E-35 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS16305 d42624d49e07b165ca8ce2c4357ecf2d 310 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 309 58.662 T 10-03-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 RG49_RS16305 d42624d49e07b165ca8ce2c4357ecf2d 310 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 308 4.6E-138 T 10-03-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 RG49_RS16305 d42624d49e07b165ca8ce2c4357ecf2d 310 Gene3D G3DSA:3.90.25.10 172 291 5.3E-37 T 10-03-2017 RG49_RS16305 d42624d49e07b165ca8ce2c4357ecf2d 310 SUPERFAMILY SSF51735 1 306 2.43E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16305 d42624d49e07b165ca8ce2c4357ecf2d 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 236 7.0E-47 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS16305 d42624d49e07b165ca8ce2c4357ecf2d 310 Gene3D G3DSA:3.40.50.720 2 171 2.8E-23 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 SUPERFAMILY SSF47203 296 447 5.64E-41 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 Gene3D G3DSA:2.40.110.10 186 281 3.7E-23 T 10-03-2017 RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 Gene3D G3DSA:1.20.140.10 282 448 4.3E-43 T 10-03-2017 RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 188 200 - T 10-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 SUPERFAMILY SSF56645 65 287 1.06E-34 T 10-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 186 280 7.6E-18 T 10-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 403 422 - T 10-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 RG49_RS12980 1114ce2ebd8e25e415cf57716cd700c7 546 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 290 444 6.5E-31 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 Gene3D G3DSA:3.30.465.10 73 229 4.4E-52 T 10-03-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 SUPERFAMILY SSF56194 202 339 2.35E-52 T 10-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 205 329 3.4E-35 T 10-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 Gene3D G3DSA:3.30.43.10 3 68 6.0E-28 T 10-03-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 342 92.231 T 10-03-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 5 330 1.4E-133 T 10-03-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 Pfam PF01565 FAD binding domain 18 149 7.5E-27 T 10-03-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 SUPERFAMILY SSF56176 3 197 2.98E-50 T 10-03-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 RG49_RS14240 6382f488f252b13fc35fd4f5d6680447 342 Gene3D G3DSA:3.90.78.10 230 341 1.1E-47 T 10-03-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 Gene3D G3DSA:3.90.25.10 264 336 6.9E-53 T 10-03-2017 RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 Gene3D G3DSA:3.90.25.10 180 232 6.9E-53 T 10-03-2017 RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 Gene3D G3DSA:3.40.50.720 1 179 1.6E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 335 1.1E-137 T 10-03-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 4.1E-57 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 SUPERFAMILY SSF51735 1 336 6.2E-93 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 PRINTS PR01713 Nucleotide sugar epimerase signature 231 246 1.8E-7 T 10-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 1.8E-7 T 10-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 RG49_RS25050 155487033363e3f5e0e1f01714ffd8c3 339 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 1.8E-7 T 10-03-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 RG49_RS07190 03b7bff065515b86e5c38cd6729de0b6 350 SUPERFAMILY SSF54506 2 167 2.62E-63 T 10-03-2017 RG49_RS07190 03b7bff065515b86e5c38cd6729de0b6 350 Gene3D G3DSA:3.10.310.10 2 175 2.9E-77 T 10-03-2017 RG49_RS07190 03b7bff065515b86e5c38cd6729de0b6 350 SUPERFAMILY SSF54506 170 350 7.32E-58 T 10-03-2017 RG49_RS07190 03b7bff065515b86e5c38cd6729de0b6 350 Gene3D G3DSA:3.10.310.10 176 328 1.9E-55 T 10-03-2017 RG49_RS07190 03b7bff065515b86e5c38cd6729de0b6 350 Pfam PF04303 PrpF protein 1 350 9.3E-162 T 10-03-2017 IPR007400 PrpF protein RG49_RS17720 5f5d0186ba0c998b0b1dc84397271212 261 Pfam PF00294 pfkB family carbohydrate kinase 23 260 3.3E-38 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS17720 5f5d0186ba0c998b0b1dc84397271212 261 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 218 231 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS17720 5f5d0186ba0c998b0b1dc84397271212 261 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 24 48 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS17720 5f5d0186ba0c998b0b1dc84397271212 261 SUPERFAMILY SSF53613 1 260 1.34E-57 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS17720 5f5d0186ba0c998b0b1dc84397271212 261 Gene3D G3DSA:3.40.1190.20 1 260 2.7E-55 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 3.0E-7 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 3.0E-7 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 Gene3D G3DSA:3.40.50.1360 80 214 2.9E-11 T 10-03-2017 RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 Pfam PF00455 DeoR C terminal sensor domain 75 231 1.5E-41 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 SUPERFAMILY SSF46785 5 73 3.04E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 Pfam PF08220 DeoR-like helix-turn-helix domain 7 60 1.4E-13 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 SMART SM00420 7 59 3.2E-12 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 SUPERFAMILY SSF100950 75 232 1.05E-26 T 10-03-2017 RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 Gene3D G3DSA:1.10.10.10 5 79 1.1E-9 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS25235 98c0dd53bcdfdb4e2d64221cd3a7dd59 251 SMART SM01134 73 233 5.5E-54 T 10-03-2017 RG49_RS05690 01f51658daa54b6fce36cc556c007d30 75 Pfam PF13993 YccJ-like protein 9 75 2.2E-38 T 10-03-2017 IPR025600 YccJ-like protein RG49_RS04655 1448673b9a3465ab1c7d40e7786b0648 210 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 9 205 2.4E-82 T 10-03-2017 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 RG49_RS04655 1448673b9a3465ab1c7d40e7786b0648 210 SUPERFAMILY SSF101473 2 204 2.22E-57 T 10-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 RG49_RS04655 1448673b9a3465ab1c7d40e7786b0648 210 SMART SM01120 32 206 1.4E-80 T 10-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 RG49_RS04655 1448673b9a3465ab1c7d40e7786b0648 210 Pfam PF02734 DAK2 domain 32 204 1.0E-55 T 10-03-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 RG49_RS14435 779729355b39f0a9064b8cd257dc0f03 105 Hamap MF_00744 Met repressor [metJ]. 1 105 42.783 T 10-03-2017 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 RG49_RS14435 779729355b39f0a9064b8cd257dc0f03 105 Gene3D G3DSA:1.10.140.10 2 105 3.0E-65 T 10-03-2017 IPR023453 Methionine repressor MetJ domain RG49_RS14435 779729355b39f0a9064b8cd257dc0f03 105 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 10 101 4.0E-49 T 10-03-2017 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 RG49_RS14435 779729355b39f0a9064b8cd257dc0f03 105 Pfam PF01340 Met Apo-repressor, MetJ 3 99 3.7E-59 T 10-03-2017 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 RG49_RS14435 779729355b39f0a9064b8cd257dc0f03 105 SUPERFAMILY SSF47598 2 105 2.45E-58 T 10-03-2017 IPR010985 Ribbon-helix-helix GO:0006355 RG49_RS01375 04b4e27c4d938f28df5074160bd0f20d 178 ProDom PD035714 MEMBRANE REGULATOR YNIB TRANSMEMBRANE YFEABCD YFEE PROBABLE LOCUS ESCHERICHIA ECS2432 1 178 2.0E-100 T 10-03-2017 RG49_RS01375 04b4e27c4d938f28df5074160bd0f20d 178 Pfam PF14002 YniB-like protein 15 177 2.5E-77 T 10-03-2017 IPR025229 YniB-like protein RG49_RS21090 7c24a07f57c22d993a2025da36b61814 109 Gene3D G3DSA:1.20.1440.40 1 104 6.4E-42 T 10-03-2017 IPR023376 YqcC-like domain RG49_RS21090 7c24a07f57c22d993a2025da36b61814 109 PIRSF PIRSF006257 1 108 2.3E-41 T 10-03-2017 IPR007384 Protein of unknown function UCP006257 RG49_RS21090 7c24a07f57c22d993a2025da36b61814 109 SUPERFAMILY SSF158452 1 106 1.7E-36 T 10-03-2017 IPR023376 YqcC-like domain RG49_RS21090 7c24a07f57c22d993a2025da36b61814 109 Pfam PF04287 tRNA pseudouridine synthase C 7 103 1.6E-33 T 10-03-2017 IPR023376 YqcC-like domain RG49_RS03405 cac1c7cb751d4612e27d6f06714e6a46 437 Gene3D G3DSA:3.30.300.30 326 433 7.8E-36 T 10-03-2017 RG49_RS03405 cac1c7cb751d4612e27d6f06714e6a46 437 Pfam PF00501 AMP-binding enzyme 80 289 7.9E-16 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS03405 cac1c7cb751d4612e27d6f06714e6a46 437 PIRSF PIRSF006444 1 434 1.7E-206 T 10-03-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 RG49_RS03405 cac1c7cb751d4612e27d6f06714e6a46 437 Gene3D G3DSA:3.40.50.980 89 245 9.8E-15 T 10-03-2017 RG49_RS03405 cac1c7cb751d4612e27d6f06714e6a46 437 SUPERFAMILY SSF56801 19 395 2.62E-61 T 10-03-2017 RG49_RS03405 cac1c7cb751d4612e27d6f06714e6a46 437 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 11 432 7.1E-239 T 10-03-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 RG49_RS03405 cac1c7cb751d4612e27d6f06714e6a46 437 Pfam PF14535 AMP-binding enzyme C-terminal domain 336 432 4.0E-26 T 10-03-2017 IPR028154 AMP-dependent ligase, C-terminal RG49_RS00085 60528112124fb9299b78826b6f99ec8a 167 Pfam PF03400 IS1 transposase 37 167 4.0E-77 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS15695 a8a802f0d44be64679e9db985d203e64 85 Pfam PF01809 Haemolytic domain 10 75 1.1E-30 T 10-03-2017 IPR002696 Putative membrane protein insertion efficiency factor RG49_RS15695 a8a802f0d44be64679e9db985d203e64 85 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 12 77 6.1E-33 T 10-03-2017 IPR002696 Putative membrane protein insertion efficiency factor RG49_RS15695 a8a802f0d44be64679e9db985d203e64 85 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 22 68 4.0E-21 T 10-03-2017 IPR002696 Putative membrane protein insertion efficiency factor RG49_RS15695 a8a802f0d44be64679e9db985d203e64 85 SMART SM01234 8 75 2.7E-45 T 10-03-2017 IPR002696 Putative membrane protein insertion efficiency factor RG49_RS15695 a8a802f0d44be64679e9db985d203e64 85 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 8 76 25.359 T 10-03-2017 IPR002696 Putative membrane protein insertion efficiency factor RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 PRINTS PR00412 Epoxide hydrolase signature 70 85 3.2E-6 T 10-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 PRINTS PR00412 Epoxide hydrolase signature 129 142 3.2E-6 T 10-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 PRINTS PR00412 Epoxide hydrolase signature 267 289 3.2E-6 T 10-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 SUPERFAMILY SSF53474 14 291 2.01E-60 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 Hamap MF_01654 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase [mhpC]. 7 292 71.048 T 10-03-2017 IPR023791 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase GO:0005737|GO:0016787|GO:0018771|GO:0019439|GO:0042803 KEGG: 00360+3.7.1.14|MetaCyc: PWY-6690 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 Pfam PF12697 Alpha/beta hydrolase family 43 284 2.9E-21 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 236 250 1.5E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 70 85 1.5E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.5E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 129 142 1.5E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09385 fb55e46a74c6b75082b16321a53f5076 293 Gene3D G3DSA:3.40.50.1820 13 291 2.7E-62 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS23340 32abce4901f1e587388d671478608386 310 Pfam PF01226 Formate/nitrite transporter 40 276 1.6E-40 T 10-03-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 RG49_RS23340 32abce4901f1e587388d671478608386 310 Gene3D G3DSA:1.20.1080.10 54 281 3.5E-47 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 SUPERFAMILY SSF56014 150 344 1.96E-61 T 10-03-2017 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 355 417 9.8E-15 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 81 138 1.5E-12 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 19 558 2.8E-303 T 10-03-2017 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 SUPERFAMILY SSF56014 428 559 2.49E-34 T 10-03-2017 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 SUPERFAMILY SSF55124 346 422 1.8E-21 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 SUPERFAMILY SSF55124 13 142 1.21E-25 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 477 493 - T 10-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Gene3D G3DSA:3.30.413.10 430 557 1.7E-34 T 10-03-2017 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Gene3D G3DSA:3.30.413.10 150 340 2.3E-73 T 10-03-2017 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Gene3D G3DSA:3.90.480.10 342 422 1.3E-62 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Gene3D G3DSA:3.90.480.10 74 146 1.3E-62 T 10-03-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 10 570 58.685 T 10-03-2017 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 PRINTS PR00397 Sirohaem Fe-binding site signature 429 447 1.5E-8 T 10-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 PRINTS PR00397 Sirohaem Fe-binding site signature 477 495 1.5E-8 T 10-03-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 173 331 1.0E-47 T 10-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS21235 2250b8fcad56045ca91c0e4b05a05c21 570 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 430 545 0.37 T 10-03-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 RG49_RS16190 2c13089ccc8ac8947d75994bef52960e 213 Gene3D G3DSA:3.40.50.2020 7 212 8.0E-84 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS16190 2c13089ccc8ac8947d75994bef52960e 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 187 2.2E-72 T 10-03-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS16190 2c13089ccc8ac8947d75994bef52960e 213 SUPERFAMILY SSF53271 2 209 4.84E-51 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS16190 2c13089ccc8ac8947d75994bef52960e 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 37.06 T 10-03-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 RG49_RS16190 2c13089ccc8ac8947d75994bef52960e 213 Pfam PF00156 Phosphoribosyl transferase domain 48 159 1.3E-11 T 10-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 Pfam PF07687 Peptidase dimerisation domain 231 318 2.3E-9 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 SUPERFAMILY SSF53187 341 430 2.77E-62 T 10-03-2017 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 SUPERFAMILY SSF53187 94 242 2.77E-62 T 10-03-2017 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 SUPERFAMILY SSF53187 2 54 2.77E-62 T 10-03-2017 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 419 3.3E-123 T 10-03-2017 IPR017439 Amidohydrolase GO:0016787 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 PIRSF PIRSF005962 1 435 3.7E-133 T 10-03-2017 IPR017439 Amidohydrolase GO:0016787 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 Pfam PF01546 Peptidase family M20/M25/M40 112 428 8.4E-28 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 Gene3D G3DSA:3.40.630.10 93 224 6.4E-75 T 10-03-2017 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 Gene3D G3DSA:3.40.630.10 338 430 6.4E-75 T 10-03-2017 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 Gene3D G3DSA:3.40.630.10 2 54 6.4E-75 T 10-03-2017 RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 Gene3D G3DSA:3.30.70.360 229 334 2.5E-27 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS03840 d2f2d677985ccf716b67afb1efe80d57 436 SUPERFAMILY SSF55031 228 335 2.99E-23 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS06070 514f423214af8c387dd808100ce010a7 400 Gene3D G3DSA:3.20.140.10 3 376 2.0E-146 T 10-03-2017 RG49_RS06070 514f423214af8c387dd808100ce010a7 400 SUPERFAMILY SSF54675 2 138 7.06E-44 T 10-03-2017 RG49_RS06070 514f423214af8c387dd808100ce010a7 400 SUPERFAMILY SSF51690 120 392 4.51E-87 T 10-03-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 RG49_RS06070 514f423214af8c387dd808100ce010a7 400 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 5 395 51.238 T 10-03-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 RG49_RS06070 514f423214af8c387dd808100ce010a7 400 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 169 394 5.4E-85 T 10-03-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 RG49_RS06070 514f423214af8c387dd808100ce010a7 400 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 8 394 1.9E-187 T 10-03-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 RG49_RS06070 514f423214af8c387dd808100ce010a7 400 PIRSF PIRSF000484 1 397 2.8E-62 T 10-03-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 SUPERFAMILY SSF54534 173 275 3.86E-28 T 10-03-2017 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 SUPERFAMILY SSF109998 25 201 5.2E-43 T 10-03-2017 IPR027304 Trigger factor/SurA domain RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 Gene3D G3DSA:3.10.50.40 282 406 5.0E-37 T 10-03-2017 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 Gene3D G3DSA:3.10.50.40 166 277 1.1E-32 T 10-03-2017 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 321 342 - T 10-03-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 Pfam PF09312 SurA N-terminal domain 25 142 1.8E-45 T 10-03-2017 IPR015391 SurA N-terminal RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 SUPERFAMILY SSF54534 283 385 1.37E-32 T 10-03-2017 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 Gene3D G3DSA:1.10.3120.10 37 115 4.1E-4 T 10-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 Pfam PF00639 PPIC-type PPIASE domain 178 272 1.9E-20 T 10-03-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 Hamap MF_01183 Chaperone SurA [surA]. 9 428 34.445 T 10-03-2017 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 Pfam PF13616 PPIC-type PPIASE domain 282 383 2.4E-26 T 10-03-2017 RG49_RS11600 3279d575a3d10c30c51847f89440205b 428 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 212 232 - T 10-03-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 Gene3D G3DSA:2.40.10.10 54 166 9.9E-12 T 10-03-2017 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 Gene3D G3DSA:2.40.10.10 177 246 6.5E-9 T 10-03-2017 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 Pfam PF00089 Trypsin 50 244 2.7E-11 T 10-03-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 PRINTS PR00839 V8 serine protease family signature 212 228 5.2E-23 T 10-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 PRINTS PR00839 V8 serine protease family signature 69 86 5.2E-23 T 10-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 PRINTS PR00839 V8 serine protease family signature 178 191 5.2E-23 T 10-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 PRINTS PR00839 V8 serine protease family signature 232 244 5.2E-23 T 10-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 PRINTS PR00839 V8 serine protease family signature 44 61 5.2E-23 T 10-03-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 80 85 - T 10-03-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 217 228 - T 10-03-2017 IPR033116 Serine proteases, trypsin family, serine active site RG49_RS02075 1c0770b725a70a6d287f6bec88adce47 273 SUPERFAMILY SSF50494 32 270 9.84E-33 T 10-03-2017 IPR009003 Peptidase S1, PA clan RG49_RS00630 5e314b5dec9369d3b0ed876ad0e66ed4 251 Pfam PF00005 ABC transporter 20 149 2.7E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS00630 5e314b5dec9369d3b0ed876ad0e66ed4 251 SUPERFAMILY SSF52540 4 215 3.53E-55 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00630 5e314b5dec9369d3b0ed876ad0e66ed4 251 Gene3D G3DSA:3.40.50.300 3 207 8.9E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00630 5e314b5dec9369d3b0ed876ad0e66ed4 251 SMART SM00382 29 199 8.6E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS07530 63b88daac06c583ed8cb43c128eed24b 310 SMART SM00797 23 298 1.6E-149 T 10-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B RG49_RS07530 63b88daac06c583ed8cb43c128eed24b 310 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 310 5.2E-146 T 10-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B RG49_RS07530 63b88daac06c583ed8cb43c128eed24b 310 Pfam PF02626 Allophanate hydrolase subunit 2 25 281 1.3E-92 T 10-03-2017 IPR003778 Carboxyltransferase domain, subdomain A and B RG49_RS07530 63b88daac06c583ed8cb43c128eed24b 310 Gene3D G3DSA:2.40.100.10 232 295 6.3E-4 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS07530 63b88daac06c583ed8cb43c128eed24b 310 SUPERFAMILY SSF50891 173 288 1.33E-11 T 10-03-2017 IPR029000 Cyclophilin-like domain RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 9 438 7.0E-203 T 10-03-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 Pfam PF04055 Radical SAM superfamily 146 323 3.1E-30 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 8 440 63.929 T 10-03-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 SMART SM00729 140 365 6.0E-56 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 SUPERFAMILY SSF102114 107 371 4.84E-54 T 10-03-2017 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 9 438 1.8E-110 T 10-03-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 Pfam PF00919 Uncharacterized protein family UPF0004 9 96 2.2E-21 T 10-03-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 Gene3D G3DSA:2.40.50.140 380 441 1.3E-25 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 144 164 - T 10-03-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 RG49_RS06830 7a9203f647687187d4c907dc465fb08d 441 Gene3D G3DSA:3.80.30.20 138 377 2.7E-76 T 10-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe RG49_RS19625 d79f43b8f4c40aef193277852d830dab 219 Gene3D G3DSA:3.40.50.2300 1 121 4.3E-36 T 10-03-2017 RG49_RS19625 d79f43b8f4c40aef193277852d830dab 219 SMART SM00862 145 216 2.3E-24 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS19625 d79f43b8f4c40aef193277852d830dab 219 SUPERFAMILY SSF52172 1 173 1.66E-35 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS19625 d79f43b8f4c40aef193277852d830dab 219 Pfam PF00072 Response regulator receiver domain 3 112 7.6E-22 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS19625 d79f43b8f4c40aef193277852d830dab 219 SMART SM00448 1 112 2.6E-38 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS19625 d79f43b8f4c40aef193277852d830dab 219 Gene3D G3DSA:1.10.10.10 122 217 9.9E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19625 d79f43b8f4c40aef193277852d830dab 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 9.5E-23 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS01845 1c7a1f26c450c8842d028a5ad0c0583b 369 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 4 367 42.463 T 10-03-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 RG49_RS01845 1c7a1f26c450c8842d028a5ad0c0583b 369 Gene3D G3DSA:3.30.420.40 145 327 9.1E-73 T 10-03-2017 RG49_RS01845 1c7a1f26c450c8842d028a5ad0c0583b 369 SUPERFAMILY SSF53067 66 111 6.04E-28 T 10-03-2017 RG49_RS01845 1c7a1f26c450c8842d028a5ad0c0583b 369 SUPERFAMILY SSF53067 143 341 6.04E-28 T 10-03-2017 RG49_RS01845 1c7a1f26c450c8842d028a5ad0c0583b 369 SUPERFAMILY SSF53067 5 37 6.04E-28 T 10-03-2017 RG49_RS01845 1c7a1f26c450c8842d028a5ad0c0583b 369 Pfam PF03702 Uncharacterised protein family (UPF0075) 5 367 2.0E-178 T 10-03-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 Hamap MF_01425 Ferrous-iron efflux pump FieF [fieF]. 1 300 67.259 T 10-03-2017 IPR023783 Cation efflux pump FieF GO:0006829|GO:0015684|GO:0016021|GO:0046873 RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 288 2.4E-80 T 10-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 Gene3D G3DSA:3.30.70.1350 207 288 3.2E-32 T 10-03-2017 IPR027470 Cation efflux protein, cytoplasmic domain RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 287 2.0E-26 T 10-03-2017 IPR027470 Cation efflux protein, cytoplasmic domain RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 Pfam PF01545 Cation efflux family 14 206 1.9E-44 T 10-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 SUPERFAMILY SSF160240 209 288 8.37E-26 T 10-03-2017 RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 SUPERFAMILY SSF161111 8 207 1.57E-51 T 10-03-2017 RG49_RS14565 cc4174eee4938d92c203544008c7e362 300 Gene3D G3DSA:1.20.1510.10 11 206 4.3E-45 T 10-03-2017 IPR027469 Cation efflux protein transmembrane domain RG49_RS14710 ece4f1a2fc4e00177ffa5a91af2e1436 309 Pfam PF04216 Protein involved in formate dehydrogenase formation 22 304 2.7E-117 T 10-03-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 RG49_RS14710 ece4f1a2fc4e00177ffa5a91af2e1436 309 Hamap MF_00611 Protein FdhE [fdhE]. 3 306 50.559 T 10-03-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 RG49_RS14710 ece4f1a2fc4e00177ffa5a91af2e1436 309 Gene3D G3DSA:3.90.1670.10 24 307 1.1E-112 T 10-03-2017 IPR024064 FdhE-like RG49_RS14710 ece4f1a2fc4e00177ffa5a91af2e1436 309 SUPERFAMILY SSF144020 24 306 2.09E-100 T 10-03-2017 IPR024064 FdhE-like RG49_RS14710 ece4f1a2fc4e00177ffa5a91af2e1436 309 PIRSF PIRSF018296 1 309 5.3E-137 T 10-03-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 RG49_RS14710 ece4f1a2fc4e00177ffa5a91af2e1436 309 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 2 305 1.3E-158 T 10-03-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 RG49_RS12020 dcfac8acd8141ebe3ef50513a40aaa29 516 PIRSF PIRSF028991 6 516 3.6E-284 T 10-03-2017 IPR016905 Glycyl radical enzyme, HI0521, predicted RG49_RS12020 dcfac8acd8141ebe3ef50513a40aaa29 516 TIGRFAM TIGR04040 glycyl_YjjI: glycine radical enzyme, YjjI family 11 504 6.8E-238 T 10-03-2017 IPR016905 Glycyl radical enzyme, HI0521, predicted RG49_RS12020 dcfac8acd8141ebe3ef50513a40aaa29 516 Gene3D G3DSA:3.20.70.20 84 253 2.3E-10 T 10-03-2017 RG49_RS12020 dcfac8acd8141ebe3ef50513a40aaa29 516 SUPERFAMILY SSF51998 24 470 1.16E-90 T 10-03-2017 RG49_RS12020 dcfac8acd8141ebe3ef50513a40aaa29 516 Pfam PF11230 Protein of unknown function (DUF3029) 22 504 1.9E-225 T 10-03-2017 IPR016905 Glycyl radical enzyme, HI0521, predicted RG49_RS19205 796ff049c9238442325ea8867b1460e6 99 Pfam PF13997 YqjK-like protein 14 86 2.7E-27 T 10-03-2017 IPR025612 YqjK-like protein RG49_RS00180 b08292274d443df3924e495d6c41199a 137 Pfam PF16973 Flagellar motor switch protein FliN N-terminal 1 49 1.5E-19 T 10-03-2017 IPR031576 Flagellar motor switch protein FliN, N-terminal RG49_RS00180 b08292274d443df3924e495d6c41199a 137 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 53 128 8.6E-34 T 10-03-2017 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00180 b08292274d443df3924e495d6c41199a 137 Gene3D G3DSA:2.30.330.10 52 136 3.8E-39 T 10-03-2017 RG49_RS00180 b08292274d443df3924e495d6c41199a 137 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 56 126 3.3E-26 T 10-03-2017 IPR001543 Surface presentation of antigen (SpoA) RG49_RS00180 b08292274d443df3924e495d6c41199a 137 SUPERFAMILY SSF101801 54 135 4.32E-27 T 10-03-2017 IPR001543 Surface presentation of antigen (SpoA) RG49_RS00180 b08292274d443df3924e495d6c41199a 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 102 117 1.8E-30 T 10-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 RG49_RS00180 b08292274d443df3924e495d6c41199a 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 56 72 1.8E-30 T 10-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 RG49_RS00180 b08292274d443df3924e495d6c41199a 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 73 89 1.8E-30 T 10-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 RG49_RS00180 b08292274d443df3924e495d6c41199a 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 89 102 1.8E-30 T 10-03-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 RG49_RS10635 58a53906e7a655fdd76cd6b736739265 491 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 69 489 8.8E-178 T 10-03-2017 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath RG49_RS10635 58a53906e7a655fdd76cd6b736739265 491 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 20 489 3.6E-212 T 10-03-2017 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 Gene3D G3DSA:3.40.50.300 324 496 1.0E-37 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 SUPERFAMILY SSF46689 536 631 8.96E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 Pfam PF00989 PAS fold 204 306 1.9E-13 T 10-03-2017 IPR013767 PAS fold GO:0006355 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 410 425 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 351 364 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 SUPERFAMILY SSF52540 331 567 1.86E-42 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 SMART SM00382 347 488 0.0016 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 Gene3D G3DSA:3.30.450.20 203 304 2.7E-11 T 10-03-2017 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 Gene3D G3DSA:1.10.8.60 498 569 5.7E-13 T 10-03-2017 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 Gene3D G3DSA:1.10.10.60 580 631 6.5E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 SMART SM00091 203 267 1.0E-5 T 10-03-2017 IPR000014 PAS domain RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 Pfam PF00158 Sigma-54 interaction domain 331 490 2.7E-35 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 Pfam PF02954 Bacterial regulatory protein, Fis family 589 628 3.4E-14 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS04645 cf1e4942f42b178bdec6650fc8766203 639 SUPERFAMILY SSF55785 198 297 7.85E-8 T 10-03-2017 IPR000014 PAS domain RG49_RS03770 6110cb33ae4819550881c982c8f524b5 866 Pfam PF06630 Enterobacterial exodeoxyribonuclease VIII 2 178 3.3E-86 T 10-03-2017 IPR010584 Exodeoxyribonuclease 8 GO:0051908|GO:0090305 RG49_RS03770 6110cb33ae4819550881c982c8f524b5 866 Pfam PF12684 PDDEXK-like domain of unknown function (DUF3799) 615 850 2.0E-33 T 10-03-2017 IPR024432 Putative exodeoxyribonuclease 8, PDDEXK-like domain RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 Gene3D G3DSA:3.90.228.20 351 539 4.6E-122 T 10-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 Gene3D G3DSA:3.90.228.20 228 290 4.6E-122 T 10-03-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 Pfam PF01293 Phosphoenolpyruvate carboxykinase 22 491 2.5E-212 T 10-03-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 4 540 5.9E-299 T 10-03-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 SUPERFAMILY SSF53795 229 540 4.84E-131 T 10-03-2017 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 265 280 - T 10-03-2017 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 16 538 56.517 T 10-03-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 Gene3D G3DSA:3.40.449.10 22 227 5.9E-89 T 10-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 PIRSF PIRSF006294 3 540 2.1E-234 T 10-03-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 RG49_RS17565 67322d9efd747328ae1f0f9c34caf12f 540 SUPERFAMILY SSF68923 9 227 1.71E-91 T 10-03-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 RG49_RS06940 8091372ffb1e79ebbdf2a52a58fbf354 295 SUPERFAMILY SSF103481 46 136 1.44E-6 T 10-03-2017 RG49_RS06940 8091372ffb1e79ebbdf2a52a58fbf354 295 SUPERFAMILY SSF103481 185 278 1.63E-10 T 10-03-2017 RG49_RS06940 8091372ffb1e79ebbdf2a52a58fbf354 295 Pfam PF00892 EamA-like transporter family 148 277 6.0E-18 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS03945 eea0ea7000d510eae36efc9635e61a16 301 Pfam PF09381 Outer membrane protein G (OmpG) 1 301 2.9E-221 T 10-03-2017 IPR018981 Outer membrane protein G RG49_RS03945 eea0ea7000d510eae36efc9635e61a16 301 SUPERFAMILY SSF56935 247 301 1.37E-6 T 10-03-2017 RG49_RS03945 eea0ea7000d510eae36efc9635e61a16 301 SUPERFAMILY SSF56935 47 201 1.37E-6 T 10-03-2017 RG49_RS03945 eea0ea7000d510eae36efc9635e61a16 301 Gene3D G3DSA:2.40.160.40 22 301 6.7E-130 T 10-03-2017 RG49_RS07385 24e689b003b14408a49a151692cf629c 522 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 501 3.0E-173 T 10-03-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 Gene3D G3DSA:1.10.10.10 407 441 7.8E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 Pfam PF06969 HemN C-terminal domain 363 431 8.7E-8 T 10-03-2017 IPR010723 HemN, C-terminal RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 PIRSF PIRSF000167 3 454 6.1E-183 T 10-03-2017 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 6 457 4.7E-244 T 10-03-2017 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 Gene3D G3DSA:3.80.30.20 53 283 1.2E-32 T 10-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 SUPERFAMILY SSF102114 6 444 1.0E-148 T 10-03-2017 RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 SMART SM00729 52 272 1.3E-58 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS14850 740de0cf66dad4cc29af44f7df31b4ef 457 Pfam PF04055 Radical SAM superfamily 57 226 5.0E-18 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS23680 5e3d279c7a066adfaa3edd0db93e2633 325 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 323 24.069 T 10-03-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23680 5e3d279c7a066adfaa3edd0db93e2633 325 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 56 71 - T 10-03-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23680 5e3d279c7a066adfaa3edd0db93e2633 325 Pfam PF00146 NADH dehydrogenase 17 317 1.5E-120 T 10-03-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23680 5e3d279c7a066adfaa3edd0db93e2633 325 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 211 224 - T 10-03-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS18950 c946773f9b258681724ad4434bc73d20 251 SUPERFAMILY SSF100950 23 250 3.6E-58 T 10-03-2017 RG49_RS18950 c946773f9b258681724ad4434bc73d20 251 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 28 239 6.5E-19 T 10-03-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 RG49_RS18950 c946773f9b258681724ad4434bc73d20 251 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 138 156 - T 10-03-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 RG49_RS18950 c946773f9b258681724ad4434bc73d20 251 Gene3D G3DSA:3.40.50.1360 22 249 2.3E-62 T 10-03-2017 RG49_RS02920 07e6492c255a0b650400bb99932324d2 143 Gene3D G3DSA:3.30.300.20 3 141 3.0E-54 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS02920 07e6492c255a0b650400bb99932324d2 143 Pfam PF02566 OsmC-like protein 43 138 4.9E-19 T 10-03-2017 IPR003718 OsmC/Ohr family RG49_RS02920 07e6492c255a0b650400bb99932324d2 143 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 138 2.2E-61 T 10-03-2017 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 RG49_RS02920 07e6492c255a0b650400bb99932324d2 143 SUPERFAMILY SSF82784 1 141 9.29E-42 T 10-03-2017 IPR003718 OsmC/Ohr family RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 Gene3D G3DSA:3.50.50.60 2 107 2.6E-28 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 SUPERFAMILY SSF51905 1 308 6.86E-39 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 Hamap MF_01651 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component [hcaD]. 1 396 70.609 T 10-03-2017 IPR023744 3-phenylpropionate/cinnamic acid dioxygenase, ferredoxin--NAD(+) reductase subunit GO:0008860|GO:0055114 KEGG: 00071+1.18.1.3 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 Pfam PF14759 Reductase C-terminal 318 400 2.7E-21 T 10-03-2017 IPR028202 Reductase, C-terminal RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.3E-21 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.3E-21 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-21 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.3E-21 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 1.3E-21 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 299 3.8E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 SUPERFAMILY SSF55424 311 400 6.18E-23 T 10-03-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 Gene3D G3DSA:3.30.390.30 318 400 7.3E-26 T 10-03-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.7E-13 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 9.7E-13 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 9.7E-13 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 9.7E-13 T 10-03-2017 RG49_RS22360 974f95778097ff09013240ea1f74cf81 400 Gene3D G3DSA:3.50.50.60 108 308 6.4E-42 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 SUPERFAMILY SSF52833 3 112 8.79E-31 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 Pfam PF14559 Tetratricopeptide repeat 124 190 1.4E-21 T 10-03-2017 RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 Pfam PF14561 Tetratricopeptide repeat 195 284 2.3E-28 T 10-03-2017 RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 Gene3D G3DSA:1.25.40.10 110 196 4.2E-37 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 SUPERFAMILY SSF48452 118 241 2.9E-8 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 Gene3D G3DSA:1.25.40.10 197 284 2.0E-33 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 Pfam PF00085 Thioredoxin 6 108 1.6E-18 T 10-03-2017 IPR013766 Thioredoxin domain GO:0045454 RG49_RS08610 78e337f55c30e8db209d8c2c35083444 284 Gene3D G3DSA:3.40.30.10 4 109 2.0E-28 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS24445 7927ac49e2e617e4dd7eeba15d52bc70 79 Pfam PF10808 Protein of unknown function (DUF2542) 1 79 6.6E-46 T 10-03-2017 IPR020155 Uncharacterised protein family YeiS GO:0016021 RG49_RS24445 7927ac49e2e617e4dd7eeba15d52bc70 79 ProDom PD058881 MEMBRANE TRANSMEMBRANE YEIS INNER 1 79 1.0E-32 T 10-03-2017 IPR020155 Uncharacterised protein family YeiS GO:0016021 RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 Gene3D G3DSA:3.40.50.300 1 206 7.7E-75 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 PIRSF PIRSF003128 1 553 7.7E-159 T 10-03-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 SUPERFAMILY SSF52540 4 50 3.86E-30 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 SUPERFAMILY SSF52540 284 507 3.86E-30 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 SUPERFAMILY SSF52540 1 217 2.15E-68 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 3.1E-173 T 10-03-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 Gene3D G3DSA:3.40.50.300 431 496 9.9E-6 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 Gene3D G3DSA:3.40.50.300 356 385 9.9E-6 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21950 c3c9850c1728556c7c806911c89bf917 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 511 1.2E-18 T 10-03-2017 IPR003395 RecF/RecN/SMC, N-terminal RG49_RS25190 7d5f33d9bbd8ffd92595c15f378a9b09 181 Gene3D G3DSA:3.40.50.300 2 181 1.9E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS25190 7d5f33d9bbd8ffd92595c15f378a9b09 181 PIRSF PIRSF006135 1 181 5.4E-65 T 10-03-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25190 7d5f33d9bbd8ffd92595c15f378a9b09 181 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 180 7.7E-64 T 10-03-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS25190 7d5f33d9bbd8ffd92595c15f378a9b09 181 SUPERFAMILY SSF52540 2 181 1.92E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15735 50d20d015fbc420b6c8bd92cc825324c 135 Gene3D G3DSA:1.10.10.690 2 134 1.6E-46 T 10-03-2017 IPR027405 YidB-like RG49_RS15735 50d20d015fbc420b6c8bd92cc825324c 135 Pfam PF06078 Bacterial protein of unknown function (DUF937) 22 110 3.2E-11 T 10-03-2017 IPR009282 Protein of unknown function DUF937 RG49_RS15735 50d20d015fbc420b6c8bd92cc825324c 135 SUPERFAMILY SSF140804 6 133 1.03E-33 T 10-03-2017 IPR027405 YidB-like RG49_RS22675 e3af5bbecb62cf2994c9eb79c05c4ac9 119 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 5 117 1.9E-48 T 10-03-2017 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 RG49_RS22675 e3af5bbecb62cf2994c9eb79c05c4ac9 119 Gene3D G3DSA:3.40.30.10 4 118 6.4E-48 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS22675 e3af5bbecb62cf2994c9eb79c05c4ac9 119 SUPERFAMILY SSF52833 5 118 5.29E-35 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS22675 e3af5bbecb62cf2994c9eb79c05c4ac9 119 Pfam PF03960 ArsC family 8 117 1.6E-22 T 10-03-2017 IPR006660 Arsenate reductase-like RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 SUPERFAMILY SSF64397 4 232 7.19E-77 T 10-03-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 Hamap MF_00117 33 kDa chaperonin [hslO]. 4 284 34.043 T 10-03-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 Gene3D G3DSA:3.55.30.10 2 176 3.5E-67 T 10-03-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 PIRSF PIRSF005261 1 285 1.7E-72 T 10-03-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 Pfam PF01430 Hsp33 protein 5 272 3.2E-86 T 10-03-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 Gene3D G3DSA:1.10.287.480 178 225 6.2E-27 T 10-03-2017 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 Gene3D G3DSA:3.90.1280.10 226 283 1.7E-25 T 10-03-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 RG49_RS17580 318d18d3118b6b44e1aed873603a898a 292 SUPERFAMILY SSF118352 225 283 3.27E-20 T 10-03-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 Hamap MF_01654 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase [mhpC]. 7 292 69.674 T 10-03-2017 IPR023791 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase GO:0005737|GO:0016787|GO:0018771|GO:0019439|GO:0042803 KEGG: 00360+3.7.1.14|MetaCyc: PWY-6690 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 SUPERFAMILY SSF53474 11 291 5.98E-61 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 PRINTS PR00412 Epoxide hydrolase signature 129 142 3.2E-6 T 10-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 PRINTS PR00412 Epoxide hydrolase signature 70 85 3.2E-6 T 10-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 PRINTS PR00412 Epoxide hydrolase signature 267 289 3.2E-6 T 10-03-2017 IPR000639 Epoxide hydrolase-like GO:0003824 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 Pfam PF00561 alpha/beta hydrolase fold 43 278 2.3E-20 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.9E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 236 250 1.9E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 129 142 1.9E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 70 85 1.9E-24 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS09945 ec4840aff39350e6f44fea759319cc07 293 Gene3D G3DSA:3.40.50.1820 12 291 2.2E-61 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS04355 b7cf7c24afbdd6b77a39a81d93ce65da 109 Gene3D G3DSA:3.10.450.140 9 109 5.0E-51 T 10-03-2017 IPR007376 dsDNA mimic, putative RG49_RS04355 b7cf7c24afbdd6b77a39a81d93ce65da 109 SUPERFAMILY SSF102816 3 109 7.32E-51 T 10-03-2017 IPR007376 dsDNA mimic, putative RG49_RS04355 b7cf7c24afbdd6b77a39a81d93ce65da 109 Hamap MF_00680 UPF0263 protein YciU [yciU]. 5 109 35.934 T 10-03-2017 IPR007376 dsDNA mimic, putative RG49_RS04355 b7cf7c24afbdd6b77a39a81d93ce65da 109 Pfam PF04269 Protein of unknown function, DUF440 8 109 9.0E-47 T 10-03-2017 IPR007376 dsDNA mimic, putative RG49_RS04355 b7cf7c24afbdd6b77a39a81d93ce65da 109 ProDom PD020447 UPF0263 YCIU HD0986 VV1228 UNCHARACTERIZED 3D-STRUCTURE VV13059 BCR PM0536 VC1208 7 109 1.0E-53 T 10-03-2017 IPR007376 dsDNA mimic, putative RG49_RS04355 b7cf7c24afbdd6b77a39a81d93ce65da 109 PIRSF PIRSF004916 1 109 2.4E-58 T 10-03-2017 IPR007376 dsDNA mimic, putative RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 SUPERFAMILY SSF54364 13 86 7.85E-29 T 10-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 9 179 30.82 T 10-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 91 177 8.4E-38 T 10-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 SUPERFAMILY SSF55200 90 179 3.92E-35 T 10-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 15 179 4.1E-78 T 10-03-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 Gene3D G3DSA:3.30.110.10 87 179 1.6E-40 T 10-03-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 15 84 8.3E-31 T 10-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 Gene3D G3DSA:3.10.20.80 13 86 1.2E-35 T 10-03-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 RG49_RS01425 45916890555801d87d58e0e9bacc14fc 180 ProSitePatterns PS00938 Initiation factor 3 signature. 66 79 - T 10-03-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 RG49_RS21255 4dc27d1a21f12988eb2f603aa2b9828d 370 Gene3D G3DSA:3.90.350.10 239 329 2.9E-8 T 10-03-2017 IPR014736 Transposase, Tn5-like, core RG49_RS21255 4dc27d1a21f12988eb2f603aa2b9828d 370 Pfam PF01609 Transposase DDE domain 107 348 1.1E-29 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS21255 4dc27d1a21f12988eb2f603aa2b9828d 370 SUPERFAMILY SSF53098 55 349 7.51E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS08240 4dc27d1a21f12988eb2f603aa2b9828d 370 Gene3D G3DSA:3.90.350.10 239 329 2.9E-8 T 10-03-2017 IPR014736 Transposase, Tn5-like, core RG49_RS08240 4dc27d1a21f12988eb2f603aa2b9828d 370 Pfam PF01609 Transposase DDE domain 107 348 1.1E-29 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS08240 4dc27d1a21f12988eb2f603aa2b9828d 370 SUPERFAMILY SSF53098 55 349 7.51E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS11805 4dc27d1a21f12988eb2f603aa2b9828d 370 Gene3D G3DSA:3.90.350.10 239 329 2.9E-8 T 10-03-2017 IPR014736 Transposase, Tn5-like, core RG49_RS11805 4dc27d1a21f12988eb2f603aa2b9828d 370 Pfam PF01609 Transposase DDE domain 107 348 1.1E-29 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS11805 4dc27d1a21f12988eb2f603aa2b9828d 370 SUPERFAMILY SSF53098 55 349 7.51E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS20325 98822156c91c8e151fc394de8e11cfce 219 SUPERFAMILY SSF100950 2 146 1.86E-46 T 10-03-2017 RG49_RS20325 98822156c91c8e151fc394de8e11cfce 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 8.9E-59 T 10-03-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 RG49_RS20325 98822156c91c8e151fc394de8e11cfce 219 Gene3D G3DSA:3.30.70.260 137 196 1.3E-30 T 10-03-2017 RG49_RS20325 98822156c91c8e151fc394de8e11cfce 219 Gene3D G3DSA:3.40.50.1360 1 136 1.7E-58 T 10-03-2017 RG49_RS20325 98822156c91c8e151fc394de8e11cfce 219 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 34.72 T 10-03-2017 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 RG49_RS20325 98822156c91c8e151fc394de8e11cfce 219 SUPERFAMILY SSF75445 127 198 2.75E-24 T 10-03-2017 RG49_RS20325 98822156c91c8e151fc394de8e11cfce 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 215 1.5E-72 T 10-03-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 252 309 2.4E-19 T 10-03-2017 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 Gene3D G3DSA:2.30.130.10 250 312 5.0E-29 T 10-03-2017 IPR015947 PUA-like domain RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 4.2E-22 T 10-03-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 SUPERFAMILY SSF55120 10 246 7.48E-86 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 11 219 2.5E-96 T 10-03-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 11 309 18.967 T 10-03-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 33 180 1.3E-57 T 10-03-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 RG49_RS18815 a877afa6369bea0714b17ebf98c3e804 314 SUPERFAMILY SSF88697 251 310 1.94E-14 T 10-03-2017 IPR015947 PUA-like domain RG49_RS12870 2e9c2b47c62d68cc5bd7285acaf56356 258 Gene3D G3DSA:3.90.226.10 2 250 1.1E-63 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS12870 2e9c2b47c62d68cc5bd7285acaf56356 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 10-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 RG49_RS12870 2e9c2b47c62d68cc5bd7285acaf56356 258 SUPERFAMILY SSF52096 2 256 1.65E-63 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS12870 2e9c2b47c62d68cc5bd7285acaf56356 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 257 4.7E-45 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS20160 d3f4a81e1ecf0eb29709388199333600 235 SUPERFAMILY SSF54060 26 230 4.12E-89 T 10-03-2017 RG49_RS20160 d3f4a81e1ecf0eb29709388199333600 235 Pfam PF04231 Endonuclease I 45 229 1.6E-45 T 10-03-2017 IPR007346 Endonuclease I GO:0004518 RG49_RS02580 97dcfd639ba3467d1eca5597a9519d83 396 Gene3D G3DSA:1.20.1250.20 207 387 2.1E-12 T 10-03-2017 RG49_RS02580 97dcfd639ba3467d1eca5597a9519d83 396 Hamap MF_00517 Probable sugar efflux transporter [sotB]. 1 390 29.99 T 10-03-2017 IPR023495 Sugar efflux transporter, putative RG49_RS02580 97dcfd639ba3467d1eca5597a9519d83 396 Pfam PF07690 Major Facilitator Superfamily 19 348 5.5E-33 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS02580 97dcfd639ba3467d1eca5597a9519d83 396 Gene3D G3DSA:1.20.1250.20 8 195 1.0E-27 T 10-03-2017 RG49_RS02580 97dcfd639ba3467d1eca5597a9519d83 396 SUPERFAMILY SSF103473 5 386 1.01E-53 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS02275 142b2201c05dbaa82136ec32a79a695e 125 Pfam PF03400 IS1 transposase 1 125 1.8E-74 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS07490 142b2201c05dbaa82136ec32a79a695e 125 Pfam PF03400 IS1 transposase 1 125 1.8E-74 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 Pfam PF12833 Helix-turn-helix domain 204 281 3.0E-19 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 234 276 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 Gene3D G3DSA:1.10.10.60 176 233 2.4E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 SUPERFAMILY SSF46689 233 283 1.08E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 SUPERFAMILY SSF46689 181 231 2.6E-5 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 280 1.3E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 264 1.3E-7 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 SMART SM00342 197 280 8.7E-33 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS23230 0609a0a5c9d4527db1bd643c118e9fd1 285 Gene3D G3DSA:1.10.10.60 234 279 2.9E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 Gene3D G3DSA:2.30.110.10 22 218 7.8E-85 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 SUPERFAMILY SSF50475 21 218 3.55E-68 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 178 218 7.5E-19 T 10-03-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 PIRSF PIRSF000190 1 218 2.5E-87 T 10-03-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 16 218 38.941 T 10-03-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 188 201 - T 10-03-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 40 122 5.6E-25 T 10-03-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS01855 703f9b9778717f8100d9df88d0cc741a 218 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 218 2.6E-105 T 10-03-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:3.40.50.740 108 203 9.6E-7 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Pfam PF01568 Molydopterin dinucleotide binding domain 1088 1202 1.6E-21 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1125 1152 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:3.40.50.740 593 778 6.7E-60 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 10-03-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Pfam PF00384 Molybdopterin oxidoreductase 108 833 2.6E-197 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:2.20.25.90 52 98 2.5E-32 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:4.10.1200.10 1 28 1.5E-19 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1235 0.0 T 10-03-2017 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 SUPERFAMILY SSF53706 4 1074 0.0 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 7.6E-17 T 10-03-2017 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:3.90.55.10 779 836 6.2E-7 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:3.40.228.10 218 336 3.1E-79 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:3.40.228.10 487 592 3.1E-79 T 10-03-2017 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 SMART SM00926 43 105 6.6E-8 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 777 794 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 SUPERFAMILY SSF50692 1081 1235 3.62E-47 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS04495 2393e1b7614eb7f7b893bb8f9ea39198 1247 Gene3D G3DSA:2.40.40.20 1054 1234 3.5E-45 T 10-03-2017 RG49_RS11445 60e578c177a169cec19325fad173e260 313 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 1 310 2.2E-136 T 10-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS11445 60e578c177a169cec19325fad173e260 313 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 311 39.581 T 10-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS11445 60e578c177a169cec19325fad173e260 313 SUPERFAMILY SSF53335 7 113 3.63E-46 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS11445 60e578c177a169cec19325fad173e260 313 SUPERFAMILY SSF53335 213 310 3.63E-46 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS11445 60e578c177a169cec19325fad173e260 313 SUPERFAMILY SSF81799 114 213 5.75E-36 T 10-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS11445 60e578c177a169cec19325fad173e260 313 Gene3D G3DSA:1.10.150.170 112 215 4.8E-39 T 10-03-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS11445 60e578c177a169cec19325fad173e260 313 PIRSF PIRSF004486 1 312 2.3E-104 T 10-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS11445 60e578c177a169cec19325fad173e260 313 Pfam PF01795 MraW methylase family 5 310 5.6E-124 T 10-03-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS11445 60e578c177a169cec19325fad173e260 313 Gene3D G3DSA:3.40.50.150 7 110 3.8E-52 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS11445 60e578c177a169cec19325fad173e260 313 Gene3D G3DSA:3.40.50.150 216 312 3.8E-52 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17940 bc63cb993d4fc125cf0565bfe89f0a2e 387 TIGRFAM TIGR01709 typeII_sec_gspL: type II secretion system protein L 6 384 1.6E-113 T 10-03-2017 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 RG49_RS17940 bc63cb993d4fc125cf0565bfe89f0a2e 387 PIRSF PIRSF015761 17 375 9.2E-11 T 10-03-2017 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 RG49_RS17940 bc63cb993d4fc125cf0565bfe89f0a2e 387 Pfam PF05134 Type II secretion system (T2SS), protein L 6 232 3.3E-72 T 10-03-2017 IPR024230 GspL, cytoplasmic actin-ATPase-like domain RG49_RS17940 bc63cb993d4fc125cf0565bfe89f0a2e 387 SUPERFAMILY SSF53067 5 143 3.24E-26 T 10-03-2017 RG49_RS17940 bc63cb993d4fc125cf0565bfe89f0a2e 387 Pfam PF12693 GspL periplasmic domain 240 384 1.1E-41 T 10-03-2017 IPR025691 GspL periplasmic domain RG49_RS12250 b3471aa543518d2a65683c8accb7e50e 318 Gene3D G3DSA:3.40.50.300 2 201 1.6E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12250 b3471aa543518d2a65683c8accb7e50e 318 Gene3D G3DSA:3.30.1220.10 208 315 1.1E-31 T 10-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal RG49_RS12250 b3471aa543518d2a65683c8accb7e50e 318 SMART SM00833 224 317 1.3E-10 T 10-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal RG49_RS12250 b3471aa543518d2a65683c8accb7e50e 318 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 224 315 1.4E-18 T 10-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal RG49_RS12250 b3471aa543518d2a65683c8accb7e50e 318 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 182 1.5E-50 T 10-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain RG49_RS12250 b3471aa543518d2a65683c8accb7e50e 318 SUPERFAMILY SSF90002 224 315 2.88E-25 T 10-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal RG49_RS12250 b3471aa543518d2a65683c8accb7e50e 318 SUPERFAMILY SSF52540 2 201 1.32E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 Gene3D G3DSA:1.10.10.60 224 272 1.2E-17 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 Gene3D G3DSA:2.60.120.10 1 77 7.6E-12 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 Pfam PF02311 AraC-like ligand binding domain 16 154 8.6E-24 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 SUPERFAMILY SSF46689 223 272 4.93E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 SUPERFAMILY SSF51215 15 158 5.49E-14 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 Gene3D G3DSA:1.10.10.60 168 223 1.8E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 SUPERFAMILY SSF46689 171 221 2.33E-8 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 Hamap MF_01534 HTH-type transcriptional activator RhaS [rhaS]. 1 273 53.355 T 10-03-2017 IPR023609 Transcription regulator HTH, RhaS GO:0003700|GO:0006355|GO:0019299 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 266 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 Pfam PF12833 Helix-turn-helix domain 193 271 8.6E-26 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 254 5.3E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 270 5.3E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS14620 42e098c414d46fec50a5e2c0949bf6eb 278 SMART SM00342 187 270 6.3E-34 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13380 6da51f605a6d8b0aed027998b72f6c2f 445 PIRSF PIRSF006060 1 435 1.0E-61 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS13380 6da51f605a6d8b0aed027998b72f6c2f 445 Pfam PF13520 Amino acid permease 12 403 6.0E-50 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 SUPERFAMILY SSF51735 123 281 5.14E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 SUPERFAMILY SSF53223 3 122 7.96E-41 T 10-03-2017 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 37.854 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 Gene3D G3DSA:3.40.50.720 140 264 6.1E-52 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 10-03-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 9.2E-89 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 9.2E-89 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 9.2E-89 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 9.2E-89 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 9.2E-89 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 9.2E-89 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 9.2E-89 T 10-03-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 6.6E-40 T 10-03-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 Gene3D G3DSA:3.40.192.10 7 139 9.2E-52 T 10-03-2017 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 279 1.1E-68 T 10-03-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS08430 d113be618dc62cbbc069c0b0fa57c93b 288 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 10-03-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 RG49_RS25095 9271ba249d38bb65421d1ba5ce43c474 356 SUPERFAMILY SSF53383 9 352 4.98E-82 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS25095 9271ba249d38bb65421d1ba5ce43c474 356 Pfam PF00155 Aminotransferase class I and II 46 351 6.7E-68 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS25095 9271ba249d38bb65421d1ba5ce43c474 356 Gene3D G3DSA:3.90.1150.10 255 352 3.5E-26 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS25095 9271ba249d38bb65421d1ba5ce43c474 356 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 352 5.9E-127 T 10-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 RG49_RS25095 9271ba249d38bb65421d1ba5ce43c474 356 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 211 220 - T 10-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 RG49_RS25095 9271ba249d38bb65421d1ba5ce43c474 356 Gene3D G3DSA:3.40.640.10 50 254 9.1E-73 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS25095 9271ba249d38bb65421d1ba5ce43c474 356 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 355 54.848 T 10-03-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 SUPERFAMILY SSF53067 153 340 3.69E-50 T 10-03-2017 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 1.2E-65 T 10-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 1.2E-65 T 10-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 1.2E-65 T 10-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 1.2E-65 T 10-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 1.2E-65 T 10-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 SUPERFAMILY SSF53067 9 152 8.89E-38 T 10-03-2017 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Pfam PF06723 MreB/Mbl protein 11 338 1.4E-150 T 10-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 9.6E-171 T 10-03-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Gene3D G3DSA:3.30.420.40 267 321 2.1E-35 T 10-03-2017 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Gene3D G3DSA:3.30.420.40 164 190 2.1E-35 T 10-03-2017 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Gene3D G3DSA:3.30.420.40 9 163 1.8E-46 T 10-03-2017 RG49_RS18365 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Gene3D G3DSA:3.90.640.10 191 263 8.7E-31 T 10-03-2017 RG49_RS17180 6f0f7dd96cefa89d272619b3bc13a515 277 SUPERFAMILY SSF161098 66 255 3.43E-19 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17180 6f0f7dd96cefa89d272619b3bc13a515 277 Gene3D G3DSA:1.10.3720.10 62 269 5.0E-18 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17180 6f0f7dd96cefa89d272619b3bc13a515 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 271 8.2E-29 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17180 6f0f7dd96cefa89d272619b3bc13a515 277 TIGRFAM TIGR02790 nickel_nikC: nickel ABC transporter, permease subunit NikC 12 268 3.6E-120 T 10-03-2017 IPR014157 Nickel ABC transporter, permease subunit NikC GO:0015099|GO:0016021 RG49_RS11370 f15937b381d17d5865f645ea1fc67679 170 PIRSF PIRSF004572 1 170 1.7E-85 T 10-03-2017 IPR009502 Secretion monitor GO:0045182 RG49_RS11370 f15937b381d17d5865f645ea1fc67679 170 ProDom PD089227 MONITOR PERIPLASMIC SECRETION PRECURSOR SIGNAL YACA 1 170 2.0E-88 T 10-03-2017 IPR009502 Secretion monitor GO:0045182 RG49_RS11370 f15937b381d17d5865f645ea1fc67679 170 Hamap MF_01332 Secretion monitor [secM]. 1 170 43.098 T 10-03-2017 IPR009502 Secretion monitor GO:0045182 RG49_RS11370 f15937b381d17d5865f645ea1fc67679 170 Pfam PF06558 Secretion monitor precursor protein (SecM) 24 167 8.1E-54 T 10-03-2017 IPR009502 Secretion monitor GO:0045182 RG49_RS01730 6a663e41d5a28c7acd663cce9cef41ba 382 PIRSF PIRSF003085 2 381 2.8E-130 T 10-03-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 RG49_RS01730 6a663e41d5a28c7acd663cce9cef41ba 382 Pfam PF02353 Mycolic acid cyclopropane synthetase 108 368 3.2E-106 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS01730 6a663e41d5a28c7acd663cce9cef41ba 382 Gene3D G3DSA:3.40.50.150 117 371 7.6E-96 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS01730 6a663e41d5a28c7acd663cce9cef41ba 382 SUPERFAMILY SSF53335 117 373 4.53E-79 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00035 4f9827293702da948e921acd4a1ae577 334 Gene3D G3DSA:3.90.420.10 67 331 6.3E-77 T 10-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 RG49_RS00035 4f9827293702da948e921acd4a1ae577 334 Pfam PF00174 Oxidoreductase molybdopterin binding domain 108 267 4.3E-29 T 10-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 RG49_RS00035 4f9827293702da948e921acd4a1ae577 334 SUPERFAMILY SSF56524 75 330 3.27E-95 T 10-03-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 RG49_RS00035 4f9827293702da948e921acd4a1ae577 334 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 2 334 61.843 T 10-03-2017 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 RG49_RS09355 ab99819abcfadfbad3415cfe4a92ad6d 403 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS09355 ab99819abcfadfbad3415cfe4a92ad6d 403 SUPERFAMILY SSF103473 7 395 1.44E-67 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS09355 ab99819abcfadfbad3415cfe4a92ad6d 403 Pfam PF07690 Major Facilitator Superfamily 21 301 6.8E-37 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS09355 ab99819abcfadfbad3415cfe4a92ad6d 403 Gene3D G3DSA:1.20.1250.20 17 193 2.2E-27 T 10-03-2017 RG49_RS09355 ab99819abcfadfbad3415cfe4a92ad6d 403 Gene3D G3DSA:1.20.1250.20 217 402 3.1E-20 T 10-03-2017 RG49_RS09355 ab99819abcfadfbad3415cfe4a92ad6d 403 ProSitePatterns PS00216 Sugar transport proteins signature 1. 70 86 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS21290 ffcab70570dbe61f0191e1376b4560c1 216 Gene3D G3DSA:3.30.70.1200 1 67 2.7E-5 T 10-03-2017 RG49_RS21290 ffcab70570dbe61f0191e1376b4560c1 216 SMART SM01101 1 212 1.1E-90 T 10-03-2017 IPR010179 CRISPR-associated protein Cse3 RG49_RS21290 ffcab70570dbe61f0191e1376b4560c1 216 SUPERFAMILY SSF117987 1 68 7.72E-10 T 10-03-2017 RG49_RS21290 ffcab70570dbe61f0191e1376b4560c1 216 Pfam PF08798 CRISPR associated protein 1 212 5.1E-51 T 10-03-2017 IPR010179 CRISPR-associated protein Cse3 RG49_RS21290 ffcab70570dbe61f0191e1376b4560c1 216 Gene3D G3DSA:3.30.70.1210 83 212 2.1E-33 T 10-03-2017 RG49_RS21290 ffcab70570dbe61f0191e1376b4560c1 216 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 1 212 8.9E-87 T 10-03-2017 IPR010179 CRISPR-associated protein Cse3 RG49_RS21290 ffcab70570dbe61f0191e1376b4560c1 216 SUPERFAMILY SSF117987 82 212 1.31E-29 T 10-03-2017 RG49_RS25245 c411960859bb9555d5c345799eabd920 97 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 61 4.3E-12 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS25245 c411960859bb9555d5c345799eabd920 97 Gene3D G3DSA:3.40.50.270 1 91 2.2E-25 T 10-03-2017 RG49_RS25245 c411960859bb9555d5c345799eabd920 97 SUPERFAMILY SSF52794 1 89 6.15E-19 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS03300 1cc6c80e6f72c2825bcfc3bfd621b952 447 Pfam PF07063 Domain of unknown function (DUF1338) 9 401 6.6E-121 T 10-03-2017 IPR009770 Domain of unknown function DUF1338 RG49_RS03300 1cc6c80e6f72c2825bcfc3bfd621b952 447 SMART SM01150 11 401 3.4E-231 T 10-03-2017 IPR009770 Domain of unknown function DUF1338 RG49_RS05085 76d08c8cacbb14514a6d7679d730e710 179 Pfam PF05433 Glycine zipper 2TM domain 73 113 9.0E-12 T 10-03-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 RG49_RS18995 66f87c86a1f0cd2c745c1a2241282873 259 Pfam PF03609 PTS system sorbose-specific iic component 5 236 3.1E-72 T 10-03-2017 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 RG49_RS24670 65e68a0e92f1beb3c87697c3ebe257da 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 2.4E-109 T 10-03-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS24670 65e68a0e92f1beb3c87697c3ebe257da 266 SUPERFAMILY SSF53613 5 265 6.86E-81 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24670 65e68a0e92f1beb3c87697c3ebe257da 266 Gene3D G3DSA:3.40.1190.20 6 263 1.1E-100 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24670 65e68a0e92f1beb3c87697c3ebe257da 266 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 4.5E-95 T 10-03-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 RG49_RS11595 b463754221f72713d04e1f23ce27c9cd 784 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 14 763 21.449 T 10-03-2017 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 RG49_RS11595 b463754221f72713d04e1f23ce27c9cd 784 Gene3D G3DSA:2.60.450.10 47 209 2.9E-25 T 10-03-2017 RG49_RS11595 b463754221f72713d04e1f23ce27c9cd 784 Pfam PF04453 Organic solvent tolerance protein 309 697 2.0E-112 T 10-03-2017 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 RG49_RS11595 b463754221f72713d04e1f23ce27c9cd 784 Pfam PF03968 OstA-like protein 53 194 2.1E-28 T 10-03-2017 IPR005653 Organic solvent tolerance-like, N-terminal RG49_RS08190 702a3b9bbbd18f771ced73b7cfd3fc9e 330 Pfam PF01032 FecCD transport family 19 324 4.5E-84 T 10-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 RG49_RS08190 702a3b9bbbd18f771ced73b7cfd3fc9e 330 Gene3D G3DSA:1.10.3470.10 6 329 4.5E-90 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS08190 702a3b9bbbd18f771ced73b7cfd3fc9e 330 SUPERFAMILY SSF81345 3 325 8.24E-72 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 SUPERFAMILY SSF54211 2 162 1.21E-49 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 Gene3D G3DSA:3.30.230.10 4 163 1.4E-54 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 Pfam PF08544 GHMP kinases C terminal 213 263 2.2E-6 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 SUPERFAMILY SSF55060 164 281 1.29E-36 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 1 282 3.8E-125 T 10-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 275 32.735 T 10-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 Pfam PF00288 GHMP kinases N terminal domain 91 148 1.3E-10 T 10-03-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 Gene3D G3DSA:3.30.70.890 166 281 2.9E-45 T 10-03-2017 IPR013750 GHMP kinase, C-terminal domain RG49_RS04590 29dbb1a117a0f251a3ad258fc2b25495 283 PIRSF PIRSF010376 1 282 2.4E-85 T 10-03-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 RG49_RS12490 ec2e20d80cbba23b6f3fb6e4ed2ffeb1 436 Pfam PF10117 McrBC 5-methylcytosine restriction system component 65 386 3.0E-96 T 10-03-2017 IPR019292 5-methylcytosine restriction system component RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SUPERFAMILY SSF50249 106 185 3.43E-14 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PIRSF PIRSF002111 1 534 2.7E-221 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SUPERFAMILY SSF50249 189 277 3.88E-27 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Gene3D G3DSA:2.40.50.140 102 172 5.5E-15 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Gene3D G3DSA:2.40.50.140 448 521 3.6E-21 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SUPERFAMILY SSF50249 429 535 1.72E-22 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 155 175 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 330 348 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 21 39 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 126 143 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 212 233 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 290 309 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 39 53 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 108 124 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 PRINTS PR00681 Ribosomal protein S1 signature 84 103 2.3E-99 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SUPERFAMILY SSF50249 362 443 1.56E-20 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SMART SM00316 19 87 6.8E-5 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SMART SM00316 190 260 2.8E-28 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SMART SM00316 449 520 2.9E-22 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SMART SM00316 275 347 2.2E-27 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SMART SM00316 362 434 3.4E-21 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SMART SM00316 103 171 2.0E-8 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Pfam PF00575 S1 RNA binding domain 361 434 9.3E-22 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Pfam PF00575 S1 RNA binding domain 104 171 8.1E-10 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Pfam PF00575 S1 RNA binding domain 449 520 4.5E-18 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Pfam PF00575 S1 RNA binding domain 20 78 7.6E-7 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Pfam PF00575 S1 RNA binding domain 275 347 2.7E-20 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Pfam PF00575 S1 RNA binding domain 190 260 2.4E-21 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SUPERFAMILY SSF50249 255 371 1.03E-31 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Gene3D G3DSA:2.40.50.140 21 101 1.3E-10 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Gene3D G3DSA:2.40.50.140 279 359 3.9E-30 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Gene3D G3DSA:2.40.50.140 192 278 6.7E-31 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 SUPERFAMILY SSF50249 1 112 9.43E-19 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 Gene3D G3DSA:2.40.50.140 360 439 5.8E-25 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06180 3a715b3d0635089e27f33e920bee8f54 557 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 1.4E-241 T 10-03-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 RG49_RS09095 71affcd52404a53dba2f3b6f1bfef285 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 3.1E-17 T 10-03-2017 IPR003849 Preprotein translocase YajC RG49_RS09095 71affcd52404a53dba2f3b6f1bfef285 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 3.1E-17 T 10-03-2017 IPR003849 Preprotein translocase YajC RG49_RS09095 71affcd52404a53dba2f3b6f1bfef285 110 SMART SM01323 19 102 4.0E-37 T 10-03-2017 IPR003849 Preprotein translocase YajC RG49_RS09095 71affcd52404a53dba2f3b6f1bfef285 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 19 102 3.0E-35 T 10-03-2017 IPR003849 Preprotein translocase YajC RG49_RS09095 71affcd52404a53dba2f3b6f1bfef285 110 Pfam PF02699 Preprotein translocase subunit 22 99 2.4E-26 T 10-03-2017 IPR003849 Preprotein translocase YajC RG49_RS24420 25039a1482469b5f2e4756711abe51d9 332 Gene3D G3DSA:3.40.50.2300 25 169 3.1E-40 T 10-03-2017 RG49_RS24420 25039a1482469b5f2e4756711abe51d9 332 Gene3D G3DSA:3.40.50.2300 170 315 1.7E-40 T 10-03-2017 RG49_RS24420 25039a1482469b5f2e4756711abe51d9 332 SUPERFAMILY SSF53822 25 330 2.94E-84 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS24420 25039a1482469b5f2e4756711abe51d9 332 Pfam PF13407 Periplasmic binding protein domain 28 299 9.8E-64 T 10-03-2017 IPR025997 Periplasmic binding protein RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 74 325 1.8E-33 T 10-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 Pfam PF05681 Fumarate hydratase (Fumerase) 51 326 5.3E-88 T 10-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 PIRSF PIRSF001394 30 548 8.0E-236 T 10-03-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 ProSitePatterns PS00163 Fumarate lyases signature. 456 465 - T 10-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 Pfam PF05683 Fumarase C-terminus 332 537 7.9E-93 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 SUPERFAMILY SSF117457 361 536 1.44E-61 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 Gene3D G3DSA:3.20.130.10 348 537 2.4E-75 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS13340 3ae4d43505c990161419f906e48968a9 548 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 373 537 9.3E-66 T 10-03-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 RG49_RS15005 8a2af18841fa7eb9027093e025edee22 89 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 3.8E-21 T 10-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 RG49_RS15005 8a2af18841fa7eb9027093e025edee22 89 Pfam PF02416 mttA/Hcf106 family 4 55 3.6E-15 T 10-03-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 RG49_RS15005 8a2af18841fa7eb9027093e025edee22 89 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 82 25.24 T 10-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 22 88 8.3E-22 T 10-03-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 106 134 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 144 3.3E-10 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 179 4.4E-7 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 255 3.5E-7 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 SUPERFAMILY SSF51161 32 316 9.29E-87 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 326 35.857 T 10-03-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 329 1.2E-131 T 10-03-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 100 128 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 259 285 0.22 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Gene3D G3DSA:2.160.10.10 141 309 7.4E-42 T 10-03-2017 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 Gene3D G3DSA:2.160.10.10 99 140 5.9E-12 T 10-03-2017 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 130 158 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS10920 c8bf2234caa71a5e1101193ea1efb001 341 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 225 253 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS04390 40b17d990f82a1c1cc648d5afe5c31f4 215 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 206 5.5E-86 T 10-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 RG49_RS04390 40b17d990f82a1c1cc648d5afe5c31f4 215 Pfam PF01914 MarC family integral membrane protein 9 210 3.7E-76 T 10-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 RG49_RS18010 a9eb05a116a704d31881e542cf92b1be 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 22.603 T 10-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 RG49_RS18010 a9eb05a116a704d31881e542cf92b1be 100 SUPERFAMILY SSF54189 6 97 2.66E-30 T 10-03-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18010 a9eb05a116a704d31881e542cf92b1be 100 Gene3D G3DSA:3.30.70.330 6 98 3.3E-34 T 10-03-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 RG49_RS18010 a9eb05a116a704d31881e542cf92b1be 100 Pfam PF00276 Ribosomal protein L23 9 95 6.0E-31 T 10-03-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 RG49_RS18010 a9eb05a116a704d31881e542cf92b1be 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 10-03-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 468 481 - T 10-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 SMART SM00962 294 495 4.7E-125 T 10-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 SUPERFAMILY SSF47364 195 274 1.7E-22 T 10-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 SUPERFAMILY SSF52540 287 494 1.25E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 SMART SM00963 200 280 3.3E-24 T 10-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 Gene3D G3DSA:1.20.120.140 185 276 5.2E-36 T 10-03-2017 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 Pfam PF00448 SRP54-type protein, GTPase domain 294 494 9.4E-80 T 10-03-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 223 495 65.982 T 10-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 Gene3D G3DSA:3.40.50.300 288 494 4.1E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 Pfam PF02881 SRP54-type protein, helical bundle domain 211 276 1.9E-13 T 10-03-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 SMART SM00382 293 484 1.1E-10 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17250 64c691d2ed73edc0ffdc93dd2539ca7a 498 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 223 494 1.8E-116 T 10-03-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 RG49_RS05320 77cdabfde36385fd29abaf433e9fab34 402 Hamap MF_01529 Multidrug resistance protein MdtH [mdtH]. 1 401 42.527 T 10-03-2017 IPR022855 Multidrug resistance protein MdtH RG49_RS05320 77cdabfde36385fd29abaf433e9fab34 402 Gene3D G3DSA:1.20.1250.20 206 386 1.2E-16 T 10-03-2017 RG49_RS05320 77cdabfde36385fd29abaf433e9fab34 402 Gene3D G3DSA:1.20.1250.20 17 186 2.1E-25 T 10-03-2017 RG49_RS05320 77cdabfde36385fd29abaf433e9fab34 402 SUPERFAMILY SSF103473 12 392 2.88E-51 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS05320 77cdabfde36385fd29abaf433e9fab34 402 Pfam PF07690 Major Facilitator Superfamily 20 239 7.5E-21 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS07200 5adfc32c620373e38308e89f4358b1d3 331 Gene3D G3DSA:2.130.10.10 2 328 1.1E-80 T 10-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 RG49_RS07200 5adfc32c620373e38308e89f4358b1d3 331 Hamap MF_01605 6-phosphogluconolactonase [pgl]. 1 331 56.289 T 10-03-2017 IPR022528 6-phosphogluconolactonase, YbhE-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 RG49_RS07200 5adfc32c620373e38308e89f4358b1d3 331 SUPERFAMILY SSF50974 3 292 9.94E-53 T 10-03-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 RG49_RS07200 5adfc32c620373e38308e89f4358b1d3 331 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 327 1.2E-87 T 10-03-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 RG49_RS14765 a335ee7b00674b6f815e0e5405ccd0d0 292 SUPERFAMILY SSF51569 3 288 3.66E-60 T 10-03-2017 RG49_RS14765 a335ee7b00674b6f815e0e5405ccd0d0 292 Gene3D G3DSA:3.20.20.70 3 289 1.7E-99 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS14765 a335ee7b00674b6f815e0e5405ccd0d0 292 PIRSF PIRSF037840 1 291 2.0E-131 T 10-03-2017 IPR017291 Sulfofructosephosphate aldolase, YihT GO:0061595|GO:1902777 MetaCyc: PWY-7446 RG49_RS14765 a335ee7b00674b6f815e0e5405ccd0d0 292 Pfam PF01791 DeoC/LacD family aldolase 17 257 1.0E-57 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS14765 a335ee7b00674b6f815e0e5405ccd0d0 292 SMART SM01133 16 258 1.8E-10 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS14765 a335ee7b00674b6f815e0e5405ccd0d0 292 Hamap MF_01912 Sulfofructosephosphate aldolase. 1 291 61.174 T 10-03-2017 IPR017291 Sulfofructosephosphate aldolase, YihT GO:0061595|GO:1902777 MetaCyc: PWY-7446 RG49_RS15780 8d11323f123715637a1283e0e9d0cc59 416 Pfam PF07676 WD40-like Beta Propeller Repeat 388 403 0.063 T 10-03-2017 IPR011659 WD40-like Beta Propeller RG49_RS15780 8d11323f123715637a1283e0e9d0cc59 416 Pfam PF12566 Protein of unknown function (DUF3748) 75 191 4.8E-56 T 10-03-2017 IPR022223 Protein of unknown function DUF3748 RG49_RS15780 8d11323f123715637a1283e0e9d0cc59 416 SUPERFAMILY SSF82171 30 111 1.49E-18 T 10-03-2017 RG49_RS15780 8d11323f123715637a1283e0e9d0cc59 416 SUPERFAMILY SSF82171 144 171 1.49E-18 T 10-03-2017 RG49_RS15780 8d11323f123715637a1283e0e9d0cc59 416 SUPERFAMILY SSF82171 282 405 1.49E-18 T 10-03-2017 RG49_RS15780 8d11323f123715637a1283e0e9d0cc59 416 Gene3D G3DSA:2.120.10.30 25 157 2.0E-31 T 10-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like RG49_RS15780 8d11323f123715637a1283e0e9d0cc59 416 Gene3D G3DSA:2.120.10.30 240 405 2.0E-31 T 10-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like RG49_RS16840 3182779ec3aa941370f3cd412da99001 62 Pfam PF10945 Cellulose biosynthesis protein BcsR 18 59 3.6E-22 T 10-03-2017 IPR024487 Cellulose biosynthesis protein BcsR RG49_RS16840 3182779ec3aa941370f3cd412da99001 62 ProDom PD053230 YHJR ECS4415 STY4179 CYTOPLASMIC 1 62 2.0E-29 T 10-03-2017 IPR024487 Cellulose biosynthesis protein BcsR RG49_RS24935 e4e5cd384f55f85a99ffe765559fb37b 407 SUPERFAMILY SSF53756 2 322 6.28E-40 T 10-03-2017 RG49_RS24935 e4e5cd384f55f85a99ffe765559fb37b 407 SUPERFAMILY SSF53756 354 403 6.28E-40 T 10-03-2017 RG49_RS24935 e4e5cd384f55f85a99ffe765559fb37b 407 TIGRFAM TIGR04007 wcaI: colanic acid biosynthesis glycosyltransferase WcaI 1 407 1.5E-271 T 10-03-2017 IPR023910 Colanic acid biosynthesis, glycosyl transferase, WcaI RG49_RS24935 e4e5cd384f55f85a99ffe765559fb37b 407 Gene3D G3DSA:3.40.50.2000 216 293 1.9E-6 T 10-03-2017 RG49_RS24935 e4e5cd384f55f85a99ffe765559fb37b 407 Pfam PF00534 Glycosyl transferases group 1 219 389 1.1E-21 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS24935 e4e5cd384f55f85a99ffe765559fb37b 407 Pfam PF13579 Glycosyl transferase 4-like domain 15 204 6.2E-28 T 10-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 RG49_RS12450 ac29b31e68529aa4f19039cb9034502f 200 Pfam PF00589 Phage integrase family 12 180 7.6E-52 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS12450 ac29b31e68529aa4f19039cb9034502f 200 Gene3D G3DSA:1.10.443.10 12 179 5.9E-39 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS12450 ac29b31e68529aa4f19039cb9034502f 200 SUPERFAMILY SSF56349 7 190 3.24E-43 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS18765 88a150e17169e37e35694a7f0ccd3ad1 110 Pfam PF03840 Preprotein translocase SecG subunit 5 72 2.2E-21 T 10-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 RG49_RS18765 88a150e17169e37e35694a7f0ccd3ad1 110 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 74 1.4E-26 T 10-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 RG49_RS18765 88a150e17169e37e35694a7f0ccd3ad1 110 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 7.8E-44 T 10-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 RG49_RS18765 88a150e17169e37e35694a7f0ccd3ad1 110 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 7.8E-44 T 10-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 RG49_RS18765 88a150e17169e37e35694a7f0ccd3ad1 110 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 7.8E-44 T 10-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 RG49_RS18765 88a150e17169e37e35694a7f0ccd3ad1 110 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 7.8E-44 T 10-03-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 RG49_RS08230 fdb53521c3b0f175393671bbf5051ae6 209 SUPERFAMILY SSF56214 105 207 7.85E-15 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS08230 fdb53521c3b0f175393671bbf5051ae6 209 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 106 201 2.7E-11 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS08230 fdb53521c3b0f175393671bbf5051ae6 209 Gene3D G3DSA:3.90.470.20 90 111 5.2E-4 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS08230 fdb53521c3b0f175393671bbf5051ae6 209 Gene3D G3DSA:3.90.470.20 112 192 1.8E-7 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS08230 fdb53521c3b0f175393671bbf5051ae6 209 PRINTS PR01399 Enterobactin synthetase component D signature 47 67 9.4E-22 T 10-03-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 RG49_RS08230 fdb53521c3b0f175393671bbf5051ae6 209 PRINTS PR01399 Enterobactin synthetase component D signature 149 165 9.4E-22 T 10-03-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 RG49_RS08230 fdb53521c3b0f175393671bbf5051ae6 209 PRINTS PR01399 Enterobactin synthetase component D signature 76 94 9.4E-22 T 10-03-2017 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 Gene3D G3DSA:3.90.55.10 517 620 7.1E-34 T 10-03-2017 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 56 835 0.0 T 10-03-2017 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 Pfam PF00384 Molybdopterin oxidoreductase 99 572 9.8E-107 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 SUPERFAMILY SSF50692 684 832 1.56E-45 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 Gene3D G3DSA:3.40.228.10 197 407 4.5E-52 T 10-03-2017 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 SUPERFAMILY SSF53706 57 674 1.57E-162 T 10-03-2017 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 515 532 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 Gene3D G3DSA:2.40.40.20 663 827 1.3E-60 T 10-03-2017 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 Pfam PF01568 Molydopterin dinucleotide binding domain 690 811 6.2E-25 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 TIGRFAM TIGR02164 torA: trimethylamine-N-oxide reductase TorA 7 835 0.0 T 10-03-2017 IPR011887 Trimethylamine-N-oxide reductase TorA GO:0030151|GO:0042597|GO:0050626 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 730 757 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 Gene3D G3DSA:3.40.50.740 408 516 2.7E-47 T 10-03-2017 RG49_RS05715 f905cba6c3d943d8565f11683fa0701a 848 Gene3D G3DSA:3.40.50.740 92 193 2.7E-47 T 10-03-2017 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 Gene3D G3DSA:3.90.79.10 229 345 3.1E-24 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 SUPERFAMILY SSF55811 220 344 3.58E-28 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 SUPERFAMILY SSF48150 3 225 1.4E-78 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 192 208 2.4E-4 T 10-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 10-03-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 Pfam PF14815 NUDIX domain 234 343 7.0E-24 T 10-03-2017 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 Gene3D G3DSA:1.10.340.30 22 122 1.9E-45 T 10-03-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 SMART SM00525 191 211 3.5E-4 T 10-03-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 SMART SM00478 39 190 2.7E-56 T 10-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 Gene3D G3DSA:1.10.1670.10 123 224 1.7E-39 T 10-03-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 277 3.3E-133 T 10-03-2017 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 168 1.8E-23 T 10-03-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 Pfam PF00633 Helix-hairpin-helix motif 100 127 4.9E-8 T 10-03-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 RG49_RS20075 14cfebc4e74a61eff5be958fc20838ea 350 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 192 208 - T 10-03-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 PIRSF PIRSF036684 1 758 0.0 T 10-03-2017 IPR012188 Malic enzyme, phosphate acetyl/butaryl transferase GO:0004473|GO:0005829|GO:0006108|GO:0016616|GO:0030145|GO:0046872|GO:0055114 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 Gene3D G3DSA:3.40.50.720 161 448 2.4E-89 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 Gene3D G3DSA:3.40.50.10380 11 160 5.3E-52 T 10-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 Pfam PF03949 Malic enzyme, NAD binding domain 165 360 1.3E-19 T 10-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 SUPERFAMILY SSF51735 163 453 2.08E-86 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 751 2.6E-102 T 10-03-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 SUPERFAMILY SSF53223 10 161 2.16E-54 T 10-03-2017 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 10-03-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 SMART SM00919 163 401 9.7E-142 T 10-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 SUPERFAMILY SSF53659 430 754 1.07E-92 T 10-03-2017 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 Gene3D G3DSA:3.40.50.10750 569 726 4.2E-55 T 10-03-2017 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 2.4E-29 T 10-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 RG49_RS22855 e4ebaf8909957a0c9f12b987e637062a 759 SMART SM01274 18 151 2.4E-83 T 10-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 PRINTS PR00069 Aldo-keto reductase signature 149 178 7.6E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 PRINTS PR00069 Aldo-keto reductase signature 114 131 7.6E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 PRINTS PR00069 Aldo-keto reductase signature 81 99 7.6E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 PRINTS PR00069 Aldo-keto reductase signature 186 210 7.6E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 PRINTS PR00069 Aldo-keto reductase signature 25 49 7.6E-46 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 Pfam PF00248 Aldo/keto reductase family 9 250 2.9E-50 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 PIRSF PIRSF000097 1 265 9.5E-68 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 114 131 - T 10-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 Gene3D G3DSA:3.20.20.100 1 259 3.3E-89 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 29 46 - T 10-03-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 RG49_RS10770 7c6bc8d3ab6fbd114bab02526ebfafad 267 SUPERFAMILY SSF51430 2 257 1.23E-82 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS17815 6dec421aecff53c08f79dd15432e59cb 134 SUPERFAMILY SSF82784 1 132 1.96E-43 T 10-03-2017 IPR003718 OsmC/Ohr family RG49_RS17815 6dec421aecff53c08f79dd15432e59cb 134 Pfam PF02566 OsmC-like protein 30 127 2.8E-19 T 10-03-2017 IPR003718 OsmC/Ohr family RG49_RS17815 6dec421aecff53c08f79dd15432e59cb 134 Gene3D G3DSA:2.20.25.10 1 34 2.7E-19 T 10-03-2017 RG49_RS17815 6dec421aecff53c08f79dd15432e59cb 134 Gene3D G3DSA:3.30.300.20 35 132 2.1E-43 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS07555 b65c20eb9d1634ad2d5c0cc0620c171e 169 Pfam PF08349 Protein of unknown function (DUF1722) 41 158 3.2E-35 T 10-03-2017 IPR013560 Domain of unknown function DUF1722 RG49_RS18705 336b4f05a160e5cc79e6d8ece23f9828 323 Gene3D G3DSA:1.10.600.10 3 322 1.6E-104 T 10-03-2017 IPR008949 Isoprenoid synthase domain RG49_RS18705 336b4f05a160e5cc79e6d8ece23f9828 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 10-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 RG49_RS18705 336b4f05a160e5cc79e6d8ece23f9828 323 SUPERFAMILY SSF48576 6 322 5.76E-101 T 10-03-2017 IPR008949 Isoprenoid synthase domain RG49_RS18705 336b4f05a160e5cc79e6d8ece23f9828 323 Pfam PF00348 Polyprenyl synthetase 30 263 9.5E-76 T 10-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 RG49_RS18705 336b4f05a160e5cc79e6d8ece23f9828 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 10-03-2017 IPR000092 Polyprenyl synthetase GO:0008299 RG49_RS17325 92a6a4240c9ef4f818663722b212482b 281 Gene3D G3DSA:1.10.3720.10 4 270 1.7E-51 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17325 92a6a4240c9ef4f818663722b212482b 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 276 1.9E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17325 92a6a4240c9ef4f818663722b212482b 281 SUPERFAMILY SSF161098 4 277 2.75E-56 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18115 b3f2d60e9479262be013fc0afb0be596 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 3.0E-55 T 10-03-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18115 b3f2d60e9479262be013fc0afb0be596 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 7 129 32.678 T 10-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 RG49_RS18115 b3f2d60e9479262be013fc0afb0be596 129 Pfam PF00411 Ribosomal protein S11 19 128 1.9E-54 T 10-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 RG49_RS18115 b3f2d60e9479262be013fc0afb0be596 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 10-03-2017 IPR018102 Ribosomal S11, conserved site RG49_RS18115 b3f2d60e9479262be013fc0afb0be596 129 Gene3D G3DSA:3.30.420.80 9 129 1.4E-54 T 10-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 RG49_RS18115 b3f2d60e9479262be013fc0afb0be596 129 SUPERFAMILY SSF53137 14 129 6.08E-48 T 10-03-2017 RG49_RS18115 b3f2d60e9479262be013fc0afb0be596 129 PIRSF PIRSF002131 1 129 5.9E-53 T 10-03-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 RG49_RS20010 905577045691a7beeea137e199cffa72 187 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 22 7.1E-5 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20010 905577045691a7beeea137e199cffa72 187 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20010 905577045691a7beeea137e199cffa72 187 Gene3D G3DSA:3.55.40.10 37 186 1.1E-42 T 10-03-2017 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 RG49_RS20010 905577045691a7beeea137e199cffa72 187 SUPERFAMILY SSF54523 6 96 3.22E-9 T 10-03-2017 RG49_RS20010 905577045691a7beeea137e199cffa72 187 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 3 177 2.8E-15 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS20010 905577045691a7beeea137e199cffa72 187 PRINTS PR00885 Bacterial general secretion pathway protein H signature 1 15 6.4E-11 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS20010 905577045691a7beeea137e199cffa72 187 PRINTS PR00885 Bacterial general secretion pathway protein H signature 141 156 6.4E-11 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS20010 905577045691a7beeea137e199cffa72 187 PRINTS PR00885 Bacterial general secretion pathway protein H signature 16 30 6.4E-11 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS20010 905577045691a7beeea137e199cffa72 187 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.7E-5 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS20010 905577045691a7beeea137e199cffa72 187 Pfam PF12019 Type II transport protein GspH 40 175 8.8E-10 T 10-03-2017 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 Gene3D G3DSA:1.10.10.10 13 142 9.2E-35 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 3.9E-25 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 3.9E-25 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 3.9E-25 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 3.9E-25 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 SUPERFAMILY SSF46785 5 143 2.87E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 10-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 Pfam PF01047 MarR family 38 96 4.1E-18 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS02570 c1f91d29301621d710549b3c6237fe96 144 SMART SM00347 31 132 3.1E-33 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS01085 c72a1b266f9fbe1de22d96a9ee89d1b4 294 PIRSF PIRSF016020 10 294 3.3E-54 T 10-03-2017 IPR025532 Glucose-6-phosphate 1-epimerase RG49_RS01085 c72a1b266f9fbe1de22d96a9ee89d1b4 294 Gene3D G3DSA:2.70.98.10 10 291 5.8E-86 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS01085 c72a1b266f9fbe1de22d96a9ee89d1b4 294 SUPERFAMILY SSF74650 8 273 8.16E-69 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS01085 c72a1b266f9fbe1de22d96a9ee89d1b4 294 Pfam PF01263 Aldose 1-epimerase 27 273 3.5E-46 T 10-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 RG49_RS00655 778f496903bce38763ee161e70354b1c 289 Pfam PF01380 SIS domain 124 252 2.6E-28 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS00655 778f496903bce38763ee161e70354b1c 289 Gene3D G3DSA:1.10.10.10 1 80 4.4E-31 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS00655 778f496903bce38763ee161e70354b1c 289 Gene3D G3DSA:3.40.50.10490 97 270 1.1E-40 T 10-03-2017 RG49_RS00655 778f496903bce38763ee161e70354b1c 289 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.4E-32 T 10-03-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 RG49_RS00655 778f496903bce38763ee161e70354b1c 289 SUPERFAMILY SSF53697 94 280 2.6E-43 T 10-03-2017 RG49_RS00655 778f496903bce38763ee161e70354b1c 289 SUPERFAMILY SSF46689 1 80 1.51E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS04765 a67b5b953b3a1b9289f33a6dd22bc79e 108 Hamap MF_01866 Protein YcgL [ycgL]. 12 99 27.74 T 10-03-2017 IPR027354 YcgL domain RG49_RS04765 a67b5b953b3a1b9289f33a6dd22bc79e 108 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 12 93 1.0E-41 T 10-03-2017 IPR027354 YcgL domain RG49_RS04765 a67b5b953b3a1b9289f33a6dd22bc79e 108 SUPERFAMILY SSF160191 4 106 3.53E-43 T 10-03-2017 RG49_RS04765 a67b5b953b3a1b9289f33a6dd22bc79e 108 Pfam PF05166 YcgL domain 14 86 1.8E-33 T 10-03-2017 IPR027354 YcgL domain RG49_RS23565 9c56481195c0a84887bc132b90327655 120 SMART SM00905 8 118 2.0E-33 T 10-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS23565 9c56481195c0a84887bc132b90327655 120 Pfam PF02152 Dihydroneopterin aldolase 8 116 2.1E-25 T 10-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS23565 9c56481195c0a84887bc132b90327655 120 TIGRFAM TIGR00526 folB_dom: FolB domain 6 120 1.5E-39 T 10-03-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS23565 9c56481195c0a84887bc132b90327655 120 SUPERFAMILY SSF55620 6 120 1.67E-31 T 10-03-2017 RG49_RS23565 9c56481195c0a84887bc132b90327655 120 Gene3D G3DSA:3.30.1130.10 3 120 3.3E-37 T 10-03-2017 RG49_RS13725 febdd3e9360726c0ffb9778a5349e88f 93 ProDom PD064934 YJCB MEMBRANE INNER ECS5042 21 93 1.0E-36 T 10-03-2017 IPR016958 Uncharacterised conserved protein UCP030798 RG49_RS13725 febdd3e9360726c0ffb9778a5349e88f 93 PIRSF PIRSF030798 1 93 4.1E-65 T 10-03-2017 IPR016958 Uncharacterised conserved protein UCP030798 RG49_RS13725 febdd3e9360726c0ffb9778a5349e88f 93 Pfam PF15940 Family of unknown function 1 90 1.8E-43 T 10-03-2017 IPR016958 Uncharacterised conserved protein UCP030798 RG49_RS05160 ca9f33268dbf27965963de3b46685bf4 340 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 1 337 4.9E-159 T 10-03-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like RG49_RS05160 ca9f33268dbf27965963de3b46685bf4 340 Gene3D G3DSA:3.30.160.60 71 109 2.2E-23 T 10-03-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 RG49_RS05160 ca9f33268dbf27965963de3b46685bf4 340 Gene3D G3DSA:3.30.160.60 303 339 7.6E-18 T 10-03-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 RG49_RS05160 ca9f33268dbf27965963de3b46685bf4 340 Pfam PF02618 YceG-like family 43 328 4.4E-78 T 10-03-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like RG49_RS06285 98cff905909c9ea46d0aa311b8f2349b 1329 SUPERFAMILY SSF52540 922 1234 5.31E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06285 98cff905909c9ea46d0aa311b8f2349b 1329 Gene3D G3DSA:3.40.50.300 922 1228 1.1E-98 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06285 98cff905909c9ea46d0aa311b8f2349b 1329 Pfam PF09397 Ftsk gamma domain 1264 1324 1.9E-28 T 10-03-2017 IPR018541 FtsK gamma domain RG49_RS06285 98cff905909c9ea46d0aa311b8f2349b 1329 SUPERFAMILY SSF46785 1263 1326 4.63E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06285 98cff905909c9ea46d0aa311b8f2349b 1329 SMART SM00843 1262 1327 4.4E-42 T 10-03-2017 IPR018541 FtsK gamma domain RG49_RS06285 98cff905909c9ea46d0aa311b8f2349b 1329 Pfam PF01580 FtsK/SpoIIIE family 948 1161 1.6E-76 T 10-03-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 RG49_RS06285 98cff905909c9ea46d0aa311b8f2349b 1329 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 20 191 9.4E-42 T 10-03-2017 IPR025199 DNA translocase FtsK, 4TM region RG49_RS01080 251a020ef856d4939eeb3d02e7d1afec 284 Gene3D G3DSA:3.20.20.100 11 275 2.6E-80 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS01080 251a020ef856d4939eeb3d02e7d1afec 284 SUPERFAMILY SSF51430 4 273 2.75E-79 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS01080 251a020ef856d4939eeb3d02e7d1afec 284 PRINTS PR00069 Aldo-keto reductase signature 127 144 3.1E-19 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01080 251a020ef856d4939eeb3d02e7d1afec 284 PRINTS PR00069 Aldo-keto reductase signature 206 230 3.1E-19 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01080 251a020ef856d4939eeb3d02e7d1afec 284 PRINTS PR00069 Aldo-keto reductase signature 97 115 3.1E-19 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01080 251a020ef856d4939eeb3d02e7d1afec 284 PRINTS PR00069 Aldo-keto reductase signature 41 65 3.1E-19 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01080 251a020ef856d4939eeb3d02e7d1afec 284 Pfam PF00248 Aldo/keto reductase family 17 271 8.9E-57 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS07025 bf533f2aef1fdd0536d0754109696a77 320 SUPERFAMILY SSF52418 75 319 7.53E-49 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS07025 bf533f2aef1fdd0536d0754109696a77 320 Gene3D G3DSA:3.40.1030.10 80 319 7.4E-42 T 10-03-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS07025 bf533f2aef1fdd0536d0754109696a77 320 Gene3D G3DSA:1.20.970.10 7 69 6.2E-19 T 10-03-2017 RG49_RS07025 bf533f2aef1fdd0536d0754109696a77 320 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 69 1.5E-10 T 10-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS07025 bf533f2aef1fdd0536d0754109696a77 320 SUPERFAMILY SSF47648 7 72 1.7E-14 T 10-03-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Gene3D G3DSA:3.30.365.10 365 451 1.2E-63 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Gene3D G3DSA:3.30.365.10 616 757 1.2E-63 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 700 1.7E-161 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Gene3D G3DSA:3.30.365.10 289 363 5.2E-29 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Gene3D G3DSA:3.30.365.10 128 180 5.2E-29 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 SMART SM01008 23 139 2.7E-45 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 SUPERFAMILY SSF54665 5 158 9.81E-40 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Gene3D G3DSA:3.30.365.10 452 606 2.4E-40 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 139 6.4E-36 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Gene3D G3DSA:3.90.1170.50 4 127 2.8E-40 T 10-03-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 Gene3D G3DSA:3.30.365.10 181 287 4.9E-35 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS20580 481fdefd608ab980df565a2abef3f5a4 765 SUPERFAMILY SSF56003 143 757 1.2E-177 T 10-03-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 RG49_RS15900 8ef52e4ae7b1adaf3a97b79e67a3d302 96 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 15 78 2.0E-14 T 10-03-2017 RG49_RS15900 8ef52e4ae7b1adaf3a97b79e67a3d302 96 SUPERFAMILY SSF55021 9 80 3.86E-16 T 10-03-2017 RG49_RS15900 8ef52e4ae7b1adaf3a97b79e67a3d302 96 Pfam PF01842 ACT domain 10 73 5.3E-10 T 10-03-2017 IPR002912 ACT domain GO:0008152|GO:0016597 RG49_RS15900 8ef52e4ae7b1adaf3a97b79e67a3d302 96 Gene3D G3DSA:3.30.70.260 10 82 5.2E-22 T 10-03-2017 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 176 - T 10-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 SUPERFAMILY SSF53187 322 406 3.28E-84 T 10-03-2017 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 SUPERFAMILY SSF53187 1 209 3.28E-84 T 10-03-2017 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 Pfam PF07687 Peptidase dimerisation domain 206 303 1.4E-11 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 10-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 Gene3D G3DSA:3.40.630.10 322 407 2.5E-119 T 10-03-2017 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 Gene3D G3DSA:3.40.630.10 1 208 2.5E-119 T 10-03-2017 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 Gene3D G3DSA:3.30.70.360 209 319 2.4E-44 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 PIRSF PIRSF037215 1 408 1.9E-182 T 10-03-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 Hamap MF_00550 Peptidase T [pepT]. 1 404 56.568 T 10-03-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 SUPERFAMILY SSF55031 208 320 2.56E-43 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 406 1.3E-157 T 10-03-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 RG49_RS04970 cc539b5eaec626aa7132f5766adb2d13 408 Pfam PF01546 Peptidase family M20/M25/M40 139 402 1.2E-16 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS18095 dbe6bebee8554c803fd1f9fd03723cdc 144 SUPERFAMILY SSF52080 4 143 1.96E-46 T 10-03-2017 IPR021131 Ribosomal protein L18e/L15P RG49_RS18095 dbe6bebee8554c803fd1f9fd03723cdc 144 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 10-03-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18095 dbe6bebee8554c803fd1f9fd03723cdc 144 Gene3D G3DSA:3.100.10.10 32 143 6.0E-27 T 10-03-2017 RG49_RS18095 dbe6bebee8554c803fd1f9fd03723cdc 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 19.545 T 10-03-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 RG49_RS18095 dbe6bebee8554c803fd1f9fd03723cdc 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.8E-51 T 10-03-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18095 dbe6bebee8554c803fd1f9fd03723cdc 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 1.9E-32 T 10-03-2017 IPR021131 Ribosomal protein L18e/L15P RG49_RS05305 627af4d6b5b1c75b5e1b3cb477762b8e 307 Gene3D G3DSA:3.30.360.10 129 306 9.1E-68 T 10-03-2017 RG49_RS05305 627af4d6b5b1c75b5e1b3cb477762b8e 307 SUPERFAMILY SSF55347 126 265 1.08E-43 T 10-03-2017 RG49_RS05305 627af4d6b5b1c75b5e1b3cb477762b8e 307 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 1.1E-25 T 10-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 RG49_RS05305 627af4d6b5b1c75b5e1b3cb477762b8e 307 SUPERFAMILY SSF51735 3 137 2.08E-42 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05305 627af4d6b5b1c75b5e1b3cb477762b8e 307 Gene3D G3DSA:3.40.50.720 2 128 2.3E-33 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20030 4613f4bb7da2528c8a87c8c77dcdfd72 392 Pfam PF12693 GspL periplasmic domain 234 391 3.1E-45 T 10-03-2017 IPR025691 GspL periplasmic domain RG49_RS20030 4613f4bb7da2528c8a87c8c77dcdfd72 392 Pfam PF05134 Type II secretion system (T2SS), protein L 37 192 6.0E-18 T 10-03-2017 IPR024230 GspL, cytoplasmic actin-ATPase-like domain RG49_RS20030 4613f4bb7da2528c8a87c8c77dcdfd72 392 TIGRFAM TIGR01709 typeII_sec_gspL: type II secretion system protein L 7 391 1.1E-107 T 10-03-2017 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 RG49_RS20030 4613f4bb7da2528c8a87c8c77dcdfd72 392 SUPERFAMILY SSF53067 2 139 2.85E-26 T 10-03-2017 RG49_RS11150 bf80fae8ad288faf707648814fc90a46 189 Gene3D G3DSA:2.60.40.1090 27 189 4.2E-21 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11150 bf80fae8ad288faf707648814fc90a46 189 SUPERFAMILY SSF49401 27 189 2.09E-16 T 10-03-2017 IPR008966 Adhesion domain RG49_RS11150 bf80fae8ad288faf707648814fc90a46 189 Pfam PF00419 Fimbrial protein 29 189 6.2E-24 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11690 332971303b58ff1c0a7f31718184bd93 196 Hamap MF_01525 Carnitine operon protein CaiE [caiE]. 1 196 65.441 T 10-03-2017 IPR023446 Carnitine operon protein CaiE RG49_RS11690 332971303b58ff1c0a7f31718184bd93 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 41 2.5E-5 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS11690 332971303b58ff1c0a7f31718184bd93 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 1.1E-7 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS11690 332971303b58ff1c0a7f31718184bd93 196 Gene3D G3DSA:2.160.10.10 4 167 5.8E-39 T 10-03-2017 RG49_RS11690 332971303b58ff1c0a7f31718184bd93 196 SUPERFAMILY SSF51161 3 167 5.41E-41 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS04040 f656e84af4843b2f7e5f55ee592a7e5b 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS04040 f656e84af4843b2f7e5f55ee592a7e5b 495 Pfam PF00171 Aldehyde dehydrogenase family 32 489 4.6E-170 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS04040 f656e84af4843b2f7e5f55ee592a7e5b 495 SUPERFAMILY SSF53720 7 492 1.31E-162 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS04040 f656e84af4843b2f7e5f55ee592a7e5b 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS04040 f656e84af4843b2f7e5f55ee592a7e5b 495 Gene3D G3DSA:3.40.309.10 281 464 2.0E-62 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS04040 f656e84af4843b2f7e5f55ee592a7e5b 495 Gene3D G3DSA:3.40.605.10 20 280 1.8E-96 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS20570 da56fd2cd0e2aaf487fb52906eeb8498 159 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 64 4.7E-7 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS20570 da56fd2cd0e2aaf487fb52906eeb8498 159 SUPERFAMILY SSF47741 89 155 1.3E-23 T 10-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 RG49_RS20570 da56fd2cd0e2aaf487fb52906eeb8498 159 Pfam PF01799 [2Fe-2S] binding domain 78 152 2.7E-24 T 10-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 RG49_RS20570 da56fd2cd0e2aaf487fb52906eeb8498 159 Gene3D G3DSA:1.10.150.120 80 155 5.8E-27 T 10-03-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 RG49_RS20570 da56fd2cd0e2aaf487fb52906eeb8498 159 SUPERFAMILY SSF54292 8 82 3.8E-19 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS20570 da56fd2cd0e2aaf487fb52906eeb8498 159 Gene3D G3DSA:3.10.20.30 7 79 1.9E-24 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS19365 9e7b731c1405f719730bee5ea85424e0 207 Gene3D G3DSA:1.10.10.10 51 151 1.6E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19365 9e7b731c1405f719730bee5ea85424e0 207 SUPERFAMILY SSF46785 63 180 4.49E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19365 9e7b731c1405f719730bee5ea85424e0 207 Pfam PF03551 Transcriptional regulator PadR-like family 67 136 6.7E-16 T 10-03-2017 IPR005149 Transcription regulator PadR, N-terminal RG49_RS18595 0b0d87592956d7cb8c345679bc86a9ec 217 SUPERFAMILY SSF52317 1 216 4.08E-66 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS18595 0b0d87592956d7cb8c345679bc86a9ec 217 PIRSF PIRSF006320 1 216 8.0E-107 T 10-03-2017 IPR026041 Glyoxalase ElbB RG49_RS18595 0b0d87592956d7cb8c345679bc86a9ec 217 Gene3D G3DSA:3.40.50.880 1 216 7.2E-103 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS01575 90ac83d7d83dbc24ffc994a5c647000a 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 51 67 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS01575 90ac83d7d83dbc24ffc994a5c647000a 393 Pfam PF07690 Major Facilitator Superfamily 2 280 1.4E-20 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS01575 90ac83d7d83dbc24ffc994a5c647000a 393 Gene3D G3DSA:1.20.1250.20 21 175 4.0E-20 T 10-03-2017 RG49_RS01575 90ac83d7d83dbc24ffc994a5c647000a 393 SUPERFAMILY SSF103473 2 384 2.88E-43 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01575 90ac83d7d83dbc24ffc994a5c647000a 393 Gene3D G3DSA:1.20.1250.20 200 387 8.7E-15 T 10-03-2017 RG49_RS03245 fe0a3cc6103c03f9fe8a6aa7552cb21a 402 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 331 1.9E-10 T 10-03-2017 IPR010095 Transposase IS605, OrfB, C-terminal RG49_RS03245 fe0a3cc6103c03f9fe8a6aa7552cb21a 402 Pfam PF12323 Helix-turn-helix domain 4 48 2.3E-12 T 10-03-2017 IPR021027 Transposase, putative, helix-turn-helix domain RG49_RS03245 fe0a3cc6103c03f9fe8a6aa7552cb21a 402 Pfam PF07282 Putative transposase DNA-binding domain 304 371 2.4E-24 T 10-03-2017 IPR010095 Transposase IS605, OrfB, C-terminal RG49_RS03245 fe0a3cc6103c03f9fe8a6aa7552cb21a 402 Pfam PF01385 Probable transposase 162 275 6.2E-31 T 10-03-2017 IPR001959 Probable transposase, IS891/IS1136/IS1341 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 SUPERFAMILY SSF55205 1 423 1.12E-146 T 10-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 420 1.5E-154 T 10-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 426 35.756 T 10-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 PIRSF PIRSF000505 1 427 1.3E-157 T 10-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 424 4.2E-140 T 10-03-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 10-03-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 10-03-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 Gene3D G3DSA:3.65.10.10 238 422 5.6E-74 T 10-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 RG49_RS06195 3d619470281596fe2c36ea304453db83 427 Gene3D G3DSA:3.65.10.10 22 237 2.2E-66 T 10-03-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 RG49_RS08905 14cb24435dc8036ccb3f450aa3bf50ec 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 7 119 1.9E-37 T 10-03-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 RG49_RS08905 14cb24435dc8036ccb3f450aa3bf50ec 132 PIRSF PIRSF003230 1 132 1.8E-21 T 10-03-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 RG49_RS08905 14cb24435dc8036ccb3f450aa3bf50ec 132 Pfam PF13279 Thioesterase-like superfamily 11 118 8.8E-16 T 10-03-2017 RG49_RS08905 14cb24435dc8036ccb3f450aa3bf50ec 132 Gene3D G3DSA:3.10.129.10 2 131 5.1E-44 T 10-03-2017 IPR029069 HotDog domain RG49_RS08905 14cb24435dc8036ccb3f450aa3bf50ec 132 SUPERFAMILY SSF54637 3 129 3.81E-38 T 10-03-2017 IPR029069 HotDog domain RG49_RS17170 757c84b5cc916734d4a91092224de0ca 268 TIGRFAM TIGR02769 nickel_nikE: nickel import ATP-binding protein NikE 2 266 4.0E-137 T 10-03-2017 IPR014137 Nickel import ATP-binding protein NikE GO:0005886|GO:0015413|GO:0015675|GO:0016151 RG49_RS17170 757c84b5cc916734d4a91092224de0ca 268 SUPERFAMILY SSF52540 4 238 5.33E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17170 757c84b5cc916734d4a91092224de0ca 268 Gene3D G3DSA:3.40.50.300 2 235 1.2E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17170 757c84b5cc916734d4a91092224de0ca 268 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17170 757c84b5cc916734d4a91092224de0ca 268 Pfam PF00005 ABC transporter 28 179 3.7E-39 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17170 757c84b5cc916734d4a91092224de0ca 268 SMART SM00382 37 229 1.3E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS22375 2efd003e6e679e0984648127783658c1 172 Pfam PF00866 Ring hydroxylating beta subunit 19 164 3.1E-49 T 10-03-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 RG49_RS22375 2efd003e6e679e0984648127783658c1 172 Hamap MF_01649 3-phenylpropionate/cinnamic acid dioxygenase subunit beta [hcaF]. 1 172 52.992 T 10-03-2017 IPR023712 3-phenylpropionate/cinnamic acid dioxygenase, beta subunit GO:0008695|GO:0055114 KEGG: 00360+1.14.12.19|MetaCyc: PWY-6690 RG49_RS22375 2efd003e6e679e0984648127783658c1 172 Gene3D G3DSA:3.10.450.50 3 172 1.2E-64 T 10-03-2017 IPR032710 NTF2-like domain RG49_RS22375 2efd003e6e679e0984648127783658c1 172 SUPERFAMILY SSF54427 5 171 3.7E-43 T 10-03-2017 IPR032710 NTF2-like domain RG49_RS04370 14f679304a75856c58991218e268f535 302 SUPERFAMILY SSF161098 100 283 3.14E-23 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04370 14f679304a75856c58991218e268f535 302 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 70 2.5E-14 T 10-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain RG49_RS04370 14f679304a75856c58991218e268f535 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 300 7.5E-26 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04370 14f679304a75856c58991218e268f535 302 Gene3D G3DSA:1.10.3720.10 102 299 1.7E-21 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS12960 7612ac245a5edc0ef7f513bfc8516f77 249 SUPERFAMILY SSF53474 9 249 6.76E-38 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS12960 7612ac245a5edc0ef7f513bfc8516f77 249 Pfam PF00326 Prolyl oligopeptidase family 86 234 2.1E-11 T 10-03-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 RG49_RS12960 7612ac245a5edc0ef7f513bfc8516f77 249 Gene3D G3DSA:3.40.50.1820 2 249 1.1E-50 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS11255 6b38f5ed43a61eea2ece7fb07abb5f4c 120 ProDom PD020773 UPF0231 YACL UNCHARACTERISED UCP006287 VC0605 UNCHARACTERIZED 3'REGION VV2750 BCR OXIDASE 1 117 2.0E-63 T 10-03-2017 IPR008249 Uncharacterised protein family UPF0231 RG49_RS11255 6b38f5ed43a61eea2ece7fb07abb5f4c 120 PIRSF PIRSF006287 1 120 8.2E-50 T 10-03-2017 IPR008249 Uncharacterised protein family UPF0231 RG49_RS11255 6b38f5ed43a61eea2ece7fb07abb5f4c 120 Hamap MF_01053 UPF0231 protein YacL [yacL]. 1 119 30.142 T 10-03-2017 IPR008249 Uncharacterised protein family UPF0231 RG49_RS11255 6b38f5ed43a61eea2ece7fb07abb5f4c 120 Pfam PF06062 Uncharacterised protein family (UPF0231) 1 117 8.6E-43 T 10-03-2017 IPR008249 Uncharacterised protein family UPF0231 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 Pfam PF02321 Outer membrane efflux protein 295 476 6.4E-10 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 Pfam PF02321 Outer membrane efflux protein 69 268 5.2E-10 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 SUPERFAMILY SSF56954 7 480 5.75E-71 T 10-03-2017 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 Gene3D G3DSA:1.20.1600.10 55 95 2.9E-66 T 10-03-2017 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 Gene3D G3DSA:1.20.1600.10 365 478 2.9E-66 T 10-03-2017 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 Gene3D G3DSA:1.20.1600.10 156 327 2.9E-66 T 10-03-2017 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 478 7.1E-81 T 10-03-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 Gene3D G3DSA:2.20.200.10 328 363 1.2E-13 T 10-03-2017 RG49_RS13590 1943d68feb5a20d773d6a2fdaa88518d 488 Gene3D G3DSA:2.20.200.10 108 155 1.2E-13 T 10-03-2017 RG49_RS16275 9ff847269ddc6b83a1a1a55392c76c1c 232 Pfam PF06176 Lipopolysaccharide core biosynthesis protein (WaaY) 1 229 1.1E-134 T 10-03-2017 IPR009330 Lipopolysaccharide core heptose(II) kinase RG49_RS16275 9ff847269ddc6b83a1a1a55392c76c1c 232 Gene3D G3DSA:1.10.510.10 143 190 6.2E-4 T 10-03-2017 RG49_RS16275 9ff847269ddc6b83a1a1a55392c76c1c 232 SUPERFAMILY SSF56112 104 180 6.31E-10 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS16275 9ff847269ddc6b83a1a1a55392c76c1c 232 SUPERFAMILY SSF56112 23 71 6.31E-10 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS24855 33400ec6d0ae67fc66a4a57ef909eb60 193 SUPERFAMILY SSF51283 1 193 9.68E-60 T 10-03-2017 IPR029054 dUTPase-like RG49_RS24855 33400ec6d0ae67fc66a4a57ef909eb60 193 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 190 34.223 T 10-03-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 RG49_RS24855 33400ec6d0ae67fc66a4a57ef909eb60 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 190 1.6E-67 T 10-03-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 RG49_RS24855 33400ec6d0ae67fc66a4a57ef909eb60 193 Pfam PF00692 dUTPase 78 185 9.6E-9 T 10-03-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 RG49_RS24855 33400ec6d0ae67fc66a4a57ef909eb60 193 Gene3D G3DSA:2.70.40.10 1 192 1.0E-60 T 10-03-2017 IPR029054 dUTPase-like RG49_RS12985 f5dfa6e11760d6698d46813f101308f5 387 SUPERFAMILY SSF56059 1 169 1.48E-84 T 10-03-2017 RG49_RS12985 f5dfa6e11760d6698d46813f101308f5 387 SUPERFAMILY SSF56059 264 384 1.48E-84 T 10-03-2017 RG49_RS12985 f5dfa6e11760d6698d46813f101308f5 387 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 14 385 1.6E-151 T 10-03-2017 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain RG49_RS12985 f5dfa6e11760d6698d46813f101308f5 387 SUPERFAMILY SSF52440 171 277 5.75E-37 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS21575 4a70a70c7fd75c55a1af29243bd9692c 187 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 5 171 2.8E-75 T 10-03-2017 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 RG49_RS21575 4a70a70c7fd75c55a1af29243bd9692c 187 PIRSF PIRSF038321 2 182 7.0E-88 T 10-03-2017 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 RG49_RS21575 4a70a70c7fd75c55a1af29243bd9692c 187 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 181 1.2E-112 T 10-03-2017 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 SUPERFAMILY SSF51230 81 156 5.76E-26 T 10-03-2017 IPR011053 Single hybrid motif RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 Pfam PF00364 Biotin-requiring enzyme 83 155 9.0E-25 T 10-03-2017 IPR000089 Biotin/lipoyl attachment RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 112 129 - T 10-03-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 Gene3D G3DSA:2.40.50.100 80 156 2.2E-32 T 10-03-2017 RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 156 1.4E-72 T 10-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 117 130 2.0E-18 T 10-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 85 98 2.0E-18 T 10-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 RG49_RS18330 36871dcfe1571efa43dd6a24b6f8caf0 156 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 102 116 2.0E-18 T 10-03-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 RG49_RS22630 8416111a4a5898e7a78c2dabd0fad02d 747 Gene3D G3DSA:3.20.20.450 496 734 1.1E-73 T 10-03-2017 IPR001633 EAL domain RG49_RS22630 8416111a4a5898e7a78c2dabd0fad02d 747 Pfam PF00563 EAL domain 498 730 1.5E-66 T 10-03-2017 IPR001633 EAL domain RG49_RS22630 8416111a4a5898e7a78c2dabd0fad02d 747 SUPERFAMILY SSF141868 497 738 1.44E-71 T 10-03-2017 IPR001633 EAL domain RG49_RS22630 8416111a4a5898e7a78c2dabd0fad02d 747 Pfam PF05231 MASE1 15 320 2.4E-67 T 10-03-2017 IPR007895 MASE1 RG49_RS22630 8416111a4a5898e7a78c2dabd0fad02d 747 SMART SM00267 319 480 3.4E-19 T 10-03-2017 IPR000160 GGDEF domain RG49_RS22630 8416111a4a5898e7a78c2dabd0fad02d 747 SMART SM00052 492 735 3.5E-107 T 10-03-2017 IPR001633 EAL domain RG49_RS08030 e0f1cc85c9d62b640c6184fbf68bd83e 98 ProDom PD015389 LYASE CITRATE ACYL CARRIER GAMMA CHAIN CITD PRECURSOR SIGNAL DIRECT 1 74 2.0E-36 T 10-03-2017 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 RG49_RS08030 e0f1cc85c9d62b640c6184fbf68bd83e 98 Hamap MF_00805 Citrate lyase acyl carrier protein [citD]. 1 97 26.922 T 10-03-2017 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 RG49_RS08030 e0f1cc85c9d62b640c6184fbf68bd83e 98 PIRSF PIRSF002736 1 97 3.0E-38 T 10-03-2017 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 RG49_RS08030 e0f1cc85c9d62b640c6184fbf68bd83e 98 TIGRFAM TIGR01608 citD: citrate lyase acyl carrier protein 1 94 1.8E-29 T 10-03-2017 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 RG49_RS08030 e0f1cc85c9d62b640c6184fbf68bd83e 98 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 5 86 8.2E-29 T 10-03-2017 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein RG49_RS08740 a7c2dce10c2ff34d22b8aa674aa75c8c 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 98 23.604 T 10-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family RG49_RS08740 a7c2dce10c2ff34d22b8aa674aa75c8c 109 Gene3D G3DSA:3.30.1310.10 1 109 1.2E-51 T 10-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family RG49_RS08740 a7c2dce10c2ff34d22b8aa674aa75c8c 109 Pfam PF02575 YbaB/EbfC DNA-binding family 11 99 1.7E-35 T 10-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family RG49_RS08740 a7c2dce10c2ff34d22b8aa674aa75c8c 109 PIRSF PIRSF004555 3 109 1.5E-39 T 10-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family RG49_RS08740 a7c2dce10c2ff34d22b8aa674aa75c8c 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 105 1.3E-42 T 10-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family RG49_RS08740 a7c2dce10c2ff34d22b8aa674aa75c8c 109 SUPERFAMILY SSF82607 11 103 1.44E-36 T 10-03-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family RG49_RS12575 175b7e4fd76eec78522d449416658e61 500 Gene3D G3DSA:3.40.50.300 16 108 3.3E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12575 175b7e4fd76eec78522d449416658e61 500 Gene3D G3DSA:3.40.50.300 204 380 3.3E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12575 175b7e4fd76eec78522d449416658e61 500 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 500 7.1E-251 T 10-03-2017 IPR033186 Helicase HerA-like C-terminal RG49_RS12575 175b7e4fd76eec78522d449416658e61 500 SUPERFAMILY SSF52540 13 369 2.13E-55 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21440 8661b27e6c644be13f4028a3476702ef 290 Gene3D G3DSA:3.40.50.300 112 281 6.9E-10 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS21440 8661b27e6c644be13f4028a3476702ef 290 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 76 289 1.6E-100 T 10-03-2017 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 RG49_RS21440 8661b27e6c644be13f4028a3476702ef 290 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 106 267 1.1E-34 T 10-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain RG49_RS21440 8661b27e6c644be13f4028a3476702ef 290 SUPERFAMILY SSF52540 88 286 1.59E-33 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22540 f2452717e02d1de341fdb881cacb465a 395 Gene3D G3DSA:1.10.150.130 98 193 1.7E-20 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS22540 f2452717e02d1de341fdb881cacb465a 395 Pfam PF00589 Phage integrase family 203 373 5.8E-23 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS22540 f2452717e02d1de341fdb881cacb465a 395 SUPERFAMILY SSF56349 98 383 7.06E-61 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS22540 f2452717e02d1de341fdb881cacb465a 395 Pfam PF13356 Domain of unknown function (DUF4102) 2 88 8.4E-17 T 10-03-2017 IPR025166 Domain of unknown function DUF4102 RG49_RS22540 f2452717e02d1de341fdb881cacb465a 395 Gene3D G3DSA:1.10.443.10 202 381 2.4E-30 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 Gene3D G3DSA:3.40.140.10 189 292 4.0E-25 T 10-03-2017 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 TIGRFAM TIGR01355 cyt_deam_dimer: cytidine deaminase 31 284 4.5E-86 T 10-03-2017 IPR006263 Cytidine deaminase, homodimeric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 60 139 1.9E-11 T 10-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 SUPERFAMILY SSF53927 1 148 6.52E-41 T 10-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 Gene3D G3DSA:3.40.140.10 34 177 2.9E-43 T 10-03-2017 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 SUPERFAMILY SSF53927 152 293 1.25E-44 T 10-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 Pfam PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region 157 276 4.7E-45 T 10-03-2017 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 102 136 - T 10-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 PIRSF PIRSF006334 14 293 1.5E-106 T 10-03-2017 IPR006263 Cytidine deaminase, homodimeric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 RG49_RS24455 cde21cad6c214513fc4fc18792eb9152 294 Hamap MF_01558 Cytidine deaminase [cdd]. 1 292 49.756 T 10-03-2017 IPR020797 Cytidine deaminase, bacteria GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 RG49_RS25130 0a1fdef87474d6b2290a245025d5a55e 274 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 213 1.5E-9 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS25130 0a1fdef87474d6b2290a245025d5a55e 274 SUPERFAMILY SSF51735 2 266 3.11E-28 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25130 0a1fdef87474d6b2290a245025d5a55e 274 Gene3D G3DSA:3.40.50.720 2 99 1.4E-9 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25130 0a1fdef87474d6b2290a245025d5a55e 274 Gene3D G3DSA:3.40.50.720 100 234 1.5E-12 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05880 b39bfa938221d3624fb3e59b2337251e 105 SMART SM00992 3 102 3.3E-33 T 10-03-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 RG49_RS05880 b39bfa938221d3624fb3e59b2337251e 105 SUPERFAMILY SSF141255 4 95 7.06E-30 T 10-03-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 RG49_RS05880 b39bfa938221d3624fb3e59b2337251e 105 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 5 96 9.3E-19 T 10-03-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 RG49_RS05880 b39bfa938221d3624fb3e59b2337251e 105 Hamap MF_01194 Heat shock protein HspQ [hspQ]. 1 105 37.369 T 10-03-2017 IPR022866 Heat shock protein HspQ RG49_RS05880 b39bfa938221d3624fb3e59b2337251e 105 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 4 102 3.8E-35 T 10-03-2017 IPR011722 Hemimethylated DNA-binding domain GO:0003677 RG49_RS07165 878e895a9d6cf67c2b7aea963aedcd08 158 SUPERFAMILY SSF49777 1 157 6.67E-53 T 10-03-2017 IPR008914 Phosphatidylethanolamine-binding protein RG49_RS07165 878e895a9d6cf67c2b7aea963aedcd08 158 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 18 157 5.7E-59 T 10-03-2017 IPR005247 YbhB/YbcL RG49_RS07165 878e895a9d6cf67c2b7aea963aedcd08 158 Pfam PF01161 Phosphatidylethanolamine-binding protein 14 157 8.5E-39 T 10-03-2017 IPR008914 Phosphatidylethanolamine-binding protein RG49_RS07165 878e895a9d6cf67c2b7aea963aedcd08 158 Gene3D G3DSA:3.90.280.10 1 158 1.1E-57 T 10-03-2017 IPR008914 Phosphatidylethanolamine-binding protein RG49_RS14905 7644fcd7f11219cf94daaad46e096a62 194 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 190 30.33 T 10-03-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 RG49_RS14905 7644fcd7f11219cf94daaad46e096a62 194 Pfam PF12804 MobA-like NTP transferase domain 9 160 3.5E-35 T 10-03-2017 IPR025877 MobA-like NTP transferase RG49_RS14905 7644fcd7f11219cf94daaad46e096a62 194 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 7 188 3.6E-69 T 10-03-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 RG49_RS14905 7644fcd7f11219cf94daaad46e096a62 194 SUPERFAMILY SSF53448 7 187 2.03E-36 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS14905 7644fcd7f11219cf94daaad46e096a62 194 Gene3D G3DSA:3.90.550.10 4 192 2.9E-61 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 SUPERFAMILY SSF51011 475 549 3.04E-17 T 10-03-2017 RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 SUPERFAMILY SSF51445 5 472 6.81E-155 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 SMART SM00642 15 414 1.0E-157 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 Gene3D G3DSA:3.90.400.10 107 175 1.4E-31 T 10-03-2017 RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 Pfam PF11941 Domain of unknown function (DUF3459) 459 548 2.5E-7 T 10-03-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 7 548 8.6E-266 T 10-03-2017 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 Gene3D G3DSA:3.20.20.80 176 473 5.3E-125 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 Gene3D G3DSA:3.20.20.80 5 106 5.3E-125 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 Gene3D G3DSA:2.60.40.1180 476 550 1.2E-19 T 10-03-2017 IPR013780 Glycosyl hydrolase, all-beta RG49_RS12695 d6ba6a9d41312e80ef4b9347f8953783 551 Pfam PF00128 Alpha amylase, catalytic domain 30 372 1.3E-127 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS19925 0256f1ad517e34581d1a27dd025f04fa 560 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 552 1.5E-235 T 10-03-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 RG49_RS19925 0256f1ad517e34581d1a27dd025f04fa 560 Pfam PF02652 L-lactate permease 16 550 6.2E-206 T 10-03-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 7 332 1.3E-140 T 10-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 330 6.4E-55 T 10-03-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 311 322 5.9E-32 T 10-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 5.9E-32 T 10-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 5.9E-32 T 10-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 5.9E-32 T 10-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 5.9E-32 T 10-03-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 SUPERFAMILY SSF53671 2 333 6.42E-99 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 1.0E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 1.0E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 1.0E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 1.0E-25 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 Gene3D G3DSA:3.40.50.1370 144 319 3.7E-74 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 Gene3D G3DSA:3.40.50.1370 4 143 3.5E-58 T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 10-03-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 9.7E-48 T 10-03-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 RG49_RS12625 001fdfa5181c94d4138ecf34c76ddba5 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 6 333 82.489 T 10-03-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 RG49_RS20640 d3ff732e60acff51f4bec434c95a6e1a 86 PIRSF PIRSF004669 1 84 4.5E-22 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS20640 d3ff732e60acff51f4bec434c95a6e1a 86 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 16 37 2.0E-23 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS20640 d3ff732e60acff51f4bec434c95a6e1a 86 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 37 52 2.0E-23 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS20640 d3ff732e60acff51f4bec434c95a6e1a 86 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 52 74 2.0E-23 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS20640 d3ff732e60acff51f4bec434c95a6e1a 86 TIGRFAM TIGR01403 fliQ_rel_III: type III secretion protein, HrpO family 4 80 3.0E-27 T 10-03-2017 IPR006306 Type III secretion protein HrpO GO:0006810|GO:0016021 RG49_RS20640 d3ff732e60acff51f4bec434c95a6e1a 86 Pfam PF01313 Bacterial export proteins, family 3 5 74 2.1E-23 T 10-03-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 RG49_RS19430 be58a2688c8a38b639f154fb0e8f8dc5 303 Pfam PF05681 Fumarate hydratase (Fumerase) 16 284 9.8E-79 T 10-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 RG49_RS19430 be58a2688c8a38b639f154fb0e8f8dc5 303 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 14 287 1.3E-123 T 10-03-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 RG49_RS01050 2da1b3dbc2fdda86bf9b48e45087b1d6 167 SUPERFAMILY SSF55826 10 163 1.96E-35 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS01050 2da1b3dbc2fdda86bf9b48e45087b1d6 167 Pfam PF04073 Aminoacyl-tRNA editing domain 30 154 1.7E-25 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS01050 2da1b3dbc2fdda86bf9b48e45087b1d6 167 Gene3D G3DSA:3.90.960.10 7 161 1.5E-33 T 10-03-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 RG49_RS24390 a96d9a8dfdfdc1b536f250efd6b696a1 278 Gene3D G3DSA:3.40.50.1820 1 276 6.0E-79 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS24390 a96d9a8dfdfdc1b536f250efd6b696a1 278 Pfam PF00756 Putative esterase 21 271 2.9E-72 T 10-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 RG49_RS24390 a96d9a8dfdfdc1b536f250efd6b696a1 278 SUPERFAMILY SSF53474 1 276 4.19E-90 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS24390 a96d9a8dfdfdc1b536f250efd6b696a1 278 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 2 275 3.8E-118 T 10-03-2017 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 RG49_RS24380 7de515daa8df4b4fba2378e7f496f93d 489 ProSitePatterns PS00218 Amino acid permeases signature. 46 77 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS24380 7de515daa8df4b4fba2378e7f496f93d 489 PIRSF PIRSF006060 1 488 8.7E-78 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS24380 7de515daa8df4b4fba2378e7f496f93d 489 Pfam PF00324 Amino acid permease 21 476 3.7E-147 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS21240 3fd3591b351d44d4a9ab20e0f0b60938 244 Gene3D G3DSA:3.40.50.620 9 216 2.0E-63 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS21240 3fd3591b351d44d4a9ab20e0f0b60938 244 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 33 243 4.1E-96 T 10-03-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 RG49_RS21240 3fd3591b351d44d4a9ab20e0f0b60938 244 SUPERFAMILY SSF52402 21 208 6.85E-53 T 10-03-2017 RG49_RS21240 3fd3591b351d44d4a9ab20e0f0b60938 244 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 9 243 40.629 T 10-03-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 RG49_RS21240 3fd3591b351d44d4a9ab20e0f0b60938 244 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 21 242 2.1E-104 T 10-03-2017 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8 RG49_RS21240 3fd3591b351d44d4a9ab20e0f0b60938 244 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 48 219 8.6E-52 T 10-03-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 RG49_RS21240 3fd3591b351d44d4a9ab20e0f0b60938 244 PIRSF PIRSF000857 6 244 2.2E-54 T 10-03-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 RG49_RS00900 6599b047ce809f202d1148b59800ef40 532 Pfam PF00563 EAL domain 272 501 1.5E-58 T 10-03-2017 IPR001633 EAL domain RG49_RS00900 6599b047ce809f202d1148b59800ef40 532 Pfam PF12792 CSS motif domain associated with EAL 43 239 8.5E-39 T 10-03-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain RG49_RS00900 6599b047ce809f202d1148b59800ef40 532 Gene3D G3DSA:3.20.20.450 271 513 1.1E-72 T 10-03-2017 IPR001633 EAL domain RG49_RS00900 6599b047ce809f202d1148b59800ef40 532 SUPERFAMILY SSF141868 272 515 1.24E-71 T 10-03-2017 IPR001633 EAL domain RG49_RS00900 6599b047ce809f202d1148b59800ef40 532 SMART SM00052 265 506 4.8E-112 T 10-03-2017 IPR001633 EAL domain RG49_RS06835 2264f342886d7a8570b58618e10f0318 442 Gene3D G3DSA:3.30.70.270 297 440 9.1E-31 T 10-03-2017 RG49_RS06835 2264f342886d7a8570b58618e10f0318 442 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 294 439 4.0E-26 T 10-03-2017 IPR000160 GGDEF domain RG49_RS06835 2264f342886d7a8570b58618e10f0318 442 SUPERFAMILY SSF55073 300 440 7.3E-29 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS06835 2264f342886d7a8570b58618e10f0318 442 Pfam PF00990 Diguanylate cyclase, GGDEF domain 295 437 7.5E-25 T 10-03-2017 IPR000160 GGDEF domain RG49_RS06835 2264f342886d7a8570b58618e10f0318 442 SMART SM00267 285 442 1.3E-45 T 10-03-2017 IPR000160 GGDEF domain RG49_RS06835 2264f342886d7a8570b58618e10f0318 442 Pfam PF17156 Gammaproteobacterial periplasmic sensor domain 26 229 5.0E-143 T 10-03-2017 IPR033422 Gammaproteobacterial periplasmic sensor domain GAPES2 RG49_RS02645 2723f970f1a1e24b3f08ed7252d87e77 291 Gene3D G3DSA:3.20.20.70 34 284 5.5E-78 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS02645 2723f970f1a1e24b3f08ed7252d87e77 291 PIRSF PIRSF038992 31 289 6.0E-86 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS02645 2723f970f1a1e24b3f08ed7252d87e77 291 SMART SM01133 51 259 6.9E-29 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS02645 2723f970f1a1e24b3f08ed7252d87e77 291 Hamap MF_02052 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [lsrF]. 1 291 75.558 T 10-03-2017 IPR033673 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase GO:0016747 KEGG: 00600+2.3.1.24 RG49_RS02645 2723f970f1a1e24b3f08ed7252d87e77 291 SUPERFAMILY SSF51569 35 275 1.9E-65 T 10-03-2017 RG49_RS02645 2723f970f1a1e24b3f08ed7252d87e77 291 Pfam PF01791 DeoC/LacD family aldolase 52 258 3.4E-18 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS21280 0042b42f245a37506f1faf20e467099e 351 Pfam PF09344 CT1975-like protein 5 334 4.2E-101 T 10-03-2017 IPR010148 CRISPR-associated protein, CT1975 RG49_RS21280 0042b42f245a37506f1faf20e467099e 351 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 3 324 6.3E-134 T 10-03-2017 IPR010148 CRISPR-associated protein, CT1975 RG49_RS13515 ed97bda1e25dac2e0837706ae13d09cb 144 SUPERFAMILY SSF55729 6 137 6.08E-27 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS13515 ed97bda1e25dac2e0837706ae13d09cb 144 Gene3D G3DSA:3.40.630.30 3 143 1.0E-30 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS13515 ed97bda1e25dac2e0837706ae13d09cb 144 Pfam PF00583 Acetyltransferase (GNAT) family 54 134 1.5E-14 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS20410 2021d31c2083ffaa600947dd0960a7c9 326 SUPERFAMILY SSF103025 6 242 1.73E-67 T 10-03-2017 RG49_RS20410 2021d31c2083ffaa600947dd0960a7c9 326 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 187 251 6.3E-26 T 10-03-2017 IPR017703 YgfZ/GcvT conserved site RG49_RS20410 2021d31c2083ffaa600947dd0960a7c9 326 Hamap MF_01175 tRNA-modifying protein YgfZ [ygfZ]. 1 321 49.599 T 10-03-2017 IPR023758 tRNA-modifying protein YgfZ GO:0005542|GO:0009451 RG49_RS20410 2021d31c2083ffaa600947dd0960a7c9 326 SUPERFAMILY SSF101790 244 325 7.19E-26 T 10-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain RG49_RS20410 2021d31c2083ffaa600947dd0960a7c9 326 Gene3D G3DSA:3.30.70.1400 27 112 1.7E-34 T 10-03-2017 RG49_RS20410 2021d31c2083ffaa600947dd0960a7c9 326 Pfam PF01571 Aminomethyltransferase folate-binding domain 31 135 5.0E-9 T 10-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal RG49_RS03035 7b9b649970b0bd5364a641ba21f11893 225 Pfam PF02665 Nitrate reductase gamma subunit 5 224 4.2E-79 T 10-03-2017 IPR023234 NarG-like domain RG49_RS03035 7b9b649970b0bd5364a641ba21f11893 225 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 225 9.0E-129 T 10-03-2017 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 RG49_RS03035 7b9b649970b0bd5364a641ba21f11893 225 SUPERFAMILY SSF103501 2 224 8.5E-70 T 10-03-2017 IPR023234 NarG-like domain RG49_RS03035 7b9b649970b0bd5364a641ba21f11893 225 Gene3D G3DSA:1.20.950.20 2 216 2.0E-70 T 10-03-2017 RG49_RS23665 f71f2fb7813aea0d11f312f70d3c5464 166 Gene3D G3DSA:3.40.30.10 86 164 6.0E-11 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS23665 f71f2fb7813aea0d11f312f70d3c5464 166 PIRSF PIRSF000216 1 166 6.5E-54 T 10-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23665 f71f2fb7813aea0d11f312f70d3c5464 166 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 22 166 7.2E-53 T 10-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23665 f71f2fb7813aea0d11f312f70d3c5464 166 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 123 141 - T 10-03-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23665 f71f2fb7813aea0d11f312f70d3c5464 166 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 23 166 3.8E-51 T 10-03-2017 RG49_RS23665 f71f2fb7813aea0d11f312f70d3c5464 166 SUPERFAMILY SSF52833 15 165 3.91E-51 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS21335 3aafe2206d465d52770b771f2cda519c 236 Gene3D G3DSA:3.90.550.10 6 233 8.4E-79 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS21335 3aafe2206d465d52770b771f2cda519c 236 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 10-03-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 RG49_RS21335 3aafe2206d465d52770b771f2cda519c 236 SUPERFAMILY SSF53448 8 227 9.97E-62 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS21335 3aafe2206d465d52770b771f2cda519c 236 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 229 8.5E-96 T 10-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 RG49_RS21335 3aafe2206d465d52770b771f2cda519c 236 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 7 230 30.95 T 10-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 RG49_RS21335 3aafe2206d465d52770b771f2cda519c 236 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 9 227 2.5E-81 T 10-03-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 RG49_RS21010 3dca18030d360a2d65805a168ed98b5d 131 Pfam PF04241 Protein of unknown function (DUF423) 20 106 1.7E-23 T 10-03-2017 IPR006696 Protein of unknown function DUF423 RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 Gene3D G3DSA:1.10.10.10 1 69 2.9E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 SUPERFAMILY SSF46785 1 70 4.57E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 Gene3D G3DSA:3.90.1150.10 349 466 7.0E-10 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 Gene3D G3DSA:3.40.640.10 133 348 7.5E-69 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 8.8E-16 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 SMART SM00345 7 66 1.2E-23 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 Pfam PF00155 Aminotransferase class I and II 122 461 9.9E-37 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS12290 c75d4e89490d932dc0744bbb9516e261 470 SUPERFAMILY SSF53383 84 465 4.35E-92 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 Pfam PF00267 Gram-negative porin 27 377 4.1E-153 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 Gene3D G3DSA:2.40.160.10 22 377 2.7E-110 T 10-03-2017 IPR023614 Porin domain RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00183 E.coli/Salmonella-type porin signature 244 261 4.6E-74 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 4.6E-74 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00183 E.coli/Salmonella-type porin signature 150 172 4.6E-74 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00183 E.coli/Salmonella-type porin signature 95 117 4.6E-74 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 4.6E-74 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00183 E.coli/Salmonella-type porin signature 275 294 4.6E-74 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 95 105 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 328 345 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 238 250 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 152 163 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS03535 66b2a68ae79f5715cd01ffbb5c3f5ca6 377 SUPERFAMILY SSF56935 22 377 1.33E-87 T 10-03-2017 RG49_RS17125 9bc4b6affc25378dadae08a0b5ff25b4 540 Gene3D G3DSA:3.60.21.10 309 413 7.5E-5 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS17125 9bc4b6affc25378dadae08a0b5ff25b4 540 SUPERFAMILY SSF56300 290 409 8.79E-6 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS17125 9bc4b6affc25378dadae08a0b5ff25b4 540 Pfam PF13258 Domain of unknown function (DUF4049) 194 503 6.9E-167 T 10-03-2017 IPR025123 Domain of unknown function DUF4049 RG49_RS06220 4f77b69d5001ba9fc7590c12d8fa535f 760 SUPERFAMILY SSF51998 4 759 5.49E-296 T 10-03-2017 RG49_RS06220 4f77b69d5001ba9fc7590c12d8fa535f 760 Pfam PF02901 Pyruvate formate lyase-like 23 614 3.7E-208 T 10-03-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 RG49_RS06220 4f77b69d5001ba9fc7590c12d8fa535f 760 Pfam PF01228 Glycine radical 630 741 4.3E-43 T 10-03-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 RG49_RS06220 4f77b69d5001ba9fc7590c12d8fa535f 760 PIRSF PIRSF000379 8 760 0.0 T 10-03-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 RG49_RS06220 4f77b69d5001ba9fc7590c12d8fa535f 760 ProSitePatterns PS00850 Glycine radical domain signature. 730 738 - T 10-03-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site RG49_RS06220 4f77b69d5001ba9fc7590c12d8fa535f 760 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 760 0.0 T 10-03-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 RG49_RS06220 4f77b69d5001ba9fc7590c12d8fa535f 760 Gene3D G3DSA:3.20.70.20 5 760 0.0 T 10-03-2017 RG49_RS13650 e13efccbda7c00032fa306b56f27c2f1 478 Pfam PF02335 Cytochrome c552 43 472 3.9E-177 T 10-03-2017 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 RG49_RS13650 e13efccbda7c00032fa306b56f27c2f1 478 Gene3D G3DSA:1.20.140.10 313 445 1.8E-56 T 10-03-2017 RG49_RS13650 e13efccbda7c00032fa306b56f27c2f1 478 PIRSF PIRSF000243 22 478 2.0E-126 T 10-03-2017 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 RG49_RS13650 e13efccbda7c00032fa306b56f27c2f1 478 TIGRFAM TIGR03152 cyto_c552_HCOOH: formate-dependent cytochrome c nitrite reductase, c552 subunit 38 475 3.8E-249 T 10-03-2017 IPR017570 Formate-dependent cytochrome c nitrite reductase, c552 subunit GO:0005509|GO:0006807|GO:0020037|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 RG49_RS13650 e13efccbda7c00032fa306b56f27c2f1 478 Hamap MF_01182 Cytochrome c-552 [nrfA]. 1 477 59.294 T 10-03-2017 IPR017570 Formate-dependent cytochrome c nitrite reductase, c552 subunit GO:0005509|GO:0006807|GO:0020037|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 RG49_RS13650 e13efccbda7c00032fa306b56f27c2f1 478 SUPERFAMILY SSF48695 38 472 2.4E-163 T 10-03-2017 IPR011031 Multihaem cytochrome RG49_RS13650 e13efccbda7c00032fa306b56f27c2f1 478 Gene3D G3DSA:1.10.710.10 110 312 1.5E-18 T 10-03-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 RG49_RS05765 ab52a56d701f4b8ec4f64047f13642de 70 Gene3D G3DSA:2.40.50.140 5 69 5.0E-15 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS05765 ab52a56d701f4b8ec4f64047f13642de 70 SMART SM00357 6 70 5.3E-17 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS05765 ab52a56d701f4b8ec4f64047f13642de 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 1.2E-22 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS05765 ab52a56d701f4b8ec4f64047f13642de 70 PIRSF PIRSF002599 1 70 5.7E-13 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS05765 ab52a56d701f4b8ec4f64047f13642de 70 SUPERFAMILY SSF50249 4 69 1.93E-14 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS05765 ab52a56d701f4b8ec4f64047f13642de 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS05330 6f259138602043a6e267b4c0031e2b2e 186 Pfam PF07273 Protein of unknown function (DUF1439) 27 178 1.1E-55 T 10-03-2017 IPR010835 Protein of unknown function DUF1439 RG49_RS03220 96115a33641245a3092bac9102d716ea 58 SUPERFAMILY SSF54786 2 58 1.22E-8 T 10-03-2017 RG49_RS03220 96115a33641245a3092bac9102d716ea 58 Gene3D G3DSA:3.30.920.30 1 58 9.1E-8 T 10-03-2017 RG49_RS03220 96115a33641245a3092bac9102d716ea 58 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 5 57 2.6E-7 T 10-03-2017 IPR012933 HicA mRNA interferase family GO:0003729 RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 Gene3D G3DSA:1.10.287.110 1 78 3.8E-27 T 10-03-2017 IPR001623 DnaJ domain RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 SMART SM00271 1 66 7.9E-9 T 10-03-2017 IPR001623 DnaJ domain RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 SUPERFAMILY SSF47144 77 170 7.06E-26 T 10-03-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 1 169 25.025 T 10-03-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 13 168 1.7E-68 T 10-03-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 SUPERFAMILY SSF46565 1 75 9.03E-18 T 10-03-2017 IPR001623 DnaJ domain RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 Pfam PF07743 HSCB C-terminal oligomerisation domain 88 161 1.1E-17 T 10-03-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 RG49_RS22435 faf6c0209a96fd32e79e56c86c191611 171 Gene3D G3DSA:1.20.1280.20 81 170 1.0E-31 T 10-03-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 SMART SM00857 2 136 6.0E-64 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 Gene3D G3DSA:1.10.10.60 138 183 5.9E-24 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 SUPERFAMILY SSF53041 1 136 4.45E-48 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 Gene3D G3DSA:3.40.50.1390 1 119 2.1E-45 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 Pfam PF00239 Resolvase, N terminal domain 3 135 3.0E-49 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 Pfam PF02796 Helix-turn-helix domain of resolvase 138 180 1.1E-11 T 10-03-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS09725 31982010cac2acf25c4952a58f6c203c 184 SUPERFAMILY SSF46689 138 180 2.51E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 SMART SM00857 2 136 6.0E-64 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 Gene3D G3DSA:1.10.10.60 138 183 5.9E-24 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 SUPERFAMILY SSF53041 1 136 4.45E-48 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 Gene3D G3DSA:3.40.50.1390 1 119 2.1E-45 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 Pfam PF00239 Resolvase, N terminal domain 3 135 3.0E-49 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 Pfam PF02796 Helix-turn-helix domain of resolvase 138 180 1.1E-11 T 10-03-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS09770 31982010cac2acf25c4952a58f6c203c 184 SUPERFAMILY SSF46689 138 180 2.51E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS05950 f02c85ffe7784203e2291bb5cd740ffe 172 Gene3D G3DSA:3.10.129.10 2 169 8.8E-62 T 10-03-2017 IPR029069 HotDog domain RG49_RS05950 f02c85ffe7784203e2291bb5cd740ffe 172 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 172 51.705 T 10-03-2017 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS05950 f02c85ffe7784203e2291bb5cd740ffe 172 Pfam PF07977 FabA-like domain 29 158 4.1E-54 T 10-03-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS05950 f02c85ffe7784203e2291bb5cd740ffe 172 SUPERFAMILY SSF54637 3 169 1.16E-55 T 10-03-2017 IPR029069 HotDog domain RG49_RS05950 f02c85ffe7784203e2291bb5cd740ffe 172 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 172 3.1E-98 T 10-03-2017 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 RG49_RS20130 2b68a56e970a5df33f6770665e758a03 234 Pfam PF01168 Alanine racemase, N-terminal domain 7 229 1.1E-29 T 10-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS20130 2b68a56e970a5df33f6770665e758a03 234 Gene3D G3DSA:3.20.20.10 1 233 3.5E-93 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS20130 2b68a56e970a5df33f6770665e758a03 234 PIRSF PIRSF004848 1 234 1.3E-74 T 10-03-2017 IPR011078 Uncharacterised protein family UPF0001 RG49_RS20130 2b68a56e970a5df33f6770665e758a03 234 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 79 93 - T 10-03-2017 IPR011078 Uncharacterised protein family UPF0001 RG49_RS20130 2b68a56e970a5df33f6770665e758a03 234 SUPERFAMILY SSF51419 1 227 1.57E-79 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS20130 2b68a56e970a5df33f6770665e758a03 234 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 229 8.7E-105 T 10-03-2017 IPR011078 Uncharacterised protein family UPF0001 RG49_RS10065 d5ca86703629be7365ab71dc235db470 112 Pfam PF01614 Bacterial transcriptional regulator 2 105 1.1E-19 T 10-03-2017 IPR014757 Transcription regulator IclR, C-terminal RG49_RS10065 d5ca86703629be7365ab71dc235db470 112 Gene3D G3DSA:3.30.450.40 2 110 1.3E-22 T 10-03-2017 IPR029016 GAF domain-like RG49_RS10065 d5ca86703629be7365ab71dc235db470 112 SUPERFAMILY SSF55781 2 105 1.5E-19 T 10-03-2017 IPR029016 GAF domain-like RG49_RS21375 eb4ce960d43a3728fb560e741e854efb 258 PIRSF PIRSF006241 1 258 4.7E-86 T 10-03-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 RG49_RS21375 eb4ce960d43a3728fb560e741e854efb 258 Gene3D G3DSA:3.20.20.150 1 257 1.5E-87 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS21375 eb4ce960d43a3728fb560e741e854efb 258 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 5.5E-33 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS21375 eb4ce960d43a3728fb560e741e854efb 258 SUPERFAMILY SSF51658 1 256 1.44E-82 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS19630 08a9b1348813752b10bb807c80c4b69b 130 SUPERFAMILY SSF101756 31 127 1.57E-36 T 10-03-2017 IPR005220 Bacterial OB-fold RG49_RS19630 08a9b1348813752b10bb807c80c4b69b 130 Pfam PF04076 Bacterial OB fold (BOF) protein 25 127 1.8E-47 T 10-03-2017 IPR005220 Bacterial OB-fold RG49_RS19630 08a9b1348813752b10bb807c80c4b69b 130 TIGRFAM TIGR00156 TIGR00156: TIGR00156 family protein 2 129 2.2E-66 T 10-03-2017 IPR016052 Bacteriophage 933W, L0136 RG49_RS19630 08a9b1348813752b10bb807c80c4b69b 130 Gene3D G3DSA:2.40.50.200 30 129 7.1E-44 T 10-03-2017 IPR005220 Bacterial OB-fold RG49_RS18175 f0b6512bf4269ac381617b10726fec38 374 Gene3D G3DSA:3.40.50.450 110 252 5.2E-9 T 10-03-2017 RG49_RS18175 f0b6512bf4269ac381617b10726fec38 374 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 64 283 4.8E-89 T 10-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 RG49_RS18175 f0b6512bf4269ac381617b10726fec38 374 Pfam PF02481 DNA recombination-mediator protein A 67 274 5.2E-71 T 10-03-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 RG49_RS18175 f0b6512bf4269ac381617b10726fec38 374 SUPERFAMILY SSF102405 78 283 3.36E-40 T 10-03-2017 RG49_RS09365 16eab1dd734a4696a6205fbad1e67dfe 82 Pfam PF12035 Protein of unknown function (DUF3521) 1 28 1.4E-6 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS04070 8d06f668ccd378db847f9214dff5ce6b 81 Pfam PF10820 Protein of unknown function (DUF2543) 1 81 1.5E-47 T 10-03-2017 IPR020251 Uncharacterised protein family, YmjA RG49_RS04070 8d06f668ccd378db847f9214dff5ce6b 81 ProDom PD059807 YMJA ECS1872 1 81 3.0E-41 T 10-03-2017 IPR020251 Uncharacterised protein family, YmjA RG49_RS09745 1721dcbda1c16159a5ac306d30707661 110 Pfam PF14282 FlxA-like protein 10 101 2.9E-16 T 10-03-2017 IPR025577 FlxA-like protein RG49_RS09700 1721dcbda1c16159a5ac306d30707661 110 Pfam PF14282 FlxA-like protein 10 101 2.9E-16 T 10-03-2017 IPR025577 FlxA-like protein RG49_RS12925 d13b73a923821ea35f86e7074f079503 284 Gene3D G3DSA:3.20.20.150 4 273 9.1E-49 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12925 d13b73a923821ea35f86e7074f079503 284 Pfam PF01261 Xylose isomerase-like TIM barrel 25 230 5.6E-32 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12925 d13b73a923821ea35f86e7074f079503 284 SUPERFAMILY SSF51658 21 275 9.43E-55 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12925 d13b73a923821ea35f86e7074f079503 284 Hamap MF_01951 L-ribulose-5-phosphate 3-epimerase UlaE [ulaE]. 1 284 81.904 T 10-03-2017 IPR023492 L-ribulose-5-phosphate 3-epimerase, Enterobacteriaceae GO:0034015 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961 RG49_RS12925 d13b73a923821ea35f86e7074f079503 284 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 4 281 5.0E-155 T 10-03-2017 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 SUPERFAMILY SSF53706 53 688 1.7E-172 T 10-03-2017 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 14 807 0.0 T 10-03-2017 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 57 76 - T 10-03-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Gene3D G3DSA:2.20.25.90 51 115 4.4E-16 T 10-03-2017 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 SMART SM00926 52 111 3.1E-9 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Pfam PF00384 Molybdopterin oxidoreductase 114 565 2.7E-88 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 SUPERFAMILY SSF50692 632 807 3.84E-38 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Gene3D G3DSA:3.40.228.10 196 399 8.0E-82 T 10-03-2017 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Gene3D G3DSA:3.40.50.740 116 195 3.1E-86 T 10-03-2017 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Gene3D G3DSA:3.40.50.740 400 645 3.1E-86 T 10-03-2017 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Gene3D G3DSA:2.40.40.20 663 807 2.4E-53 T 10-03-2017 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 722 749 - T 10-03-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 52 111 1.5E-13 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02135 3ae62eba40d3e4199f5016e7d03549ac 807 Pfam PF01568 Molydopterin dinucleotide binding domain 686 799 8.0E-27 T 10-03-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 RG49_RS23255 b89b8135a0832160fefc7ab66c6078a5 306 PIRSF PIRSF026649 3 305 1.2E-91 T 10-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 RG49_RS23255 b89b8135a0832160fefc7ab66c6078a5 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 296 2.0E-118 T 10-03-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 RG49_RS23255 b89b8135a0832160fefc7ab66c6078a5 306 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 5 305 4.5E-143 T 10-03-2017 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 RG49_RS23255 b89b8135a0832160fefc7ab66c6078a5 306 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 4 305 49.096 T 10-03-2017 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 RG49_RS23255 b89b8135a0832160fefc7ab66c6078a5 306 Hamap MF_01943 Lipid A biosynthesis palmitoleoyltransferase [lpxP]. 3 305 69.438 T 10-03-2017 IPR030857 Lipid A biosynthesis palmitoleoyltransferase, LpxP GO:0008951|GO:0009409|GO:0036104 KEGG: 00600+2.3.1.24 RG49_RS24285 5c0779adb72f1e9cf8e5c533f356469e 328 SMART SM00833 240 323 4.7E-4 T 10-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal RG49_RS24285 5c0779adb72f1e9cf8e5c533f356469e 328 Gene3D G3DSA:3.40.50.300 5 189 4.7E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24285 5c0779adb72f1e9cf8e5c533f356469e 328 SUPERFAMILY SSF52540 6 170 5.33E-26 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24285 5c0779adb72f1e9cf8e5c533f356469e 328 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 171 2.2E-39 T 10-03-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain RG49_RS24285 5c0779adb72f1e9cf8e5c533f356469e 328 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 242 321 3.4E-5 T 10-03-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 253 6.1E-102 T 10-03-2017 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 Gene3D G3DSA:3.40.190.10 116 212 9.8E-32 T 10-03-2017 RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 SUPERFAMILY SSF53850 1 257 6.29E-66 T 10-03-2017 RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 254 2.0E-63 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 10-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 Gene3D G3DSA:3.40.190.10 215 257 2.3E-43 T 10-03-2017 RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 Gene3D G3DSA:3.40.190.10 26 113 2.3E-43 T 10-03-2017 RG49_RS23535 c4cdd1b70c465cb610c9f2b2a1983a58 260 SMART SM00062 27 256 4.4E-72 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS20695 eb6da5e6398cd1be3ed8e58ad273c65e 193 Pfam PF09482 Bacterial type III secretion apparatus protein (OrgA_MxiK) 6 170 2.7E-31 T 10-03-2017 IPR013388 Type III secretion apparatus protein OrgA/MxiK GO:0009405 RG49_RS20695 eb6da5e6398cd1be3ed8e58ad273c65e 193 TIGRFAM TIGR02555 OrgA_MxiK: type III secretion apparatus protein OrgA/MxiK 5 189 4.5E-74 T 10-03-2017 IPR013388 Type III secretion apparatus protein OrgA/MxiK GO:0009405 RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 11 390 2.7E-156 T 10-03-2017 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 282 371 7.7E-19 T 10-03-2017 IPR023885 4Fe4S-binding SPASM domain RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 SUPERFAMILY SSF102114 20 352 2.49E-41 T 10-03-2017 RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 Pfam PF13186 Iron-sulfur cluster-binding domain 283 343 3.3E-11 T 10-03-2017 IPR023885 4Fe4S-binding SPASM domain RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 141 402 1.0E-17 T 10-03-2017 RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 Gene3D G3DSA:3.20.20.70 19 358 2.0E-47 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 Pfam PF13353 4Fe-4S single cluster domain 19 135 2.4E-5 T 10-03-2017 RG49_RS15205 65f0340619ab4eb85faa86197b9a7c9f 411 Pfam PF04055 Radical SAM superfamily 20 173 6.6E-13 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS08055 c735e01d1db86756ade346e80d07e441 487 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 25 480 1.2E-172 T 10-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 RG49_RS08055 c735e01d1db86756ade346e80d07e441 487 Pfam PF00939 Sodium:sulfate symporter transmembrane region 6 486 1.8E-185 T 10-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 RG49_RS08055 c735e01d1db86756ade346e80d07e441 487 PIRSF PIRSF002457 1 487 1.1E-162 T 10-03-2017 IPR030676 Citrate carrier CitT-related RG49_RS01160 e6c1af58a06160fc94e702b4ca64be72 183 Gene3D G3DSA:3.40.109.10 1 168 2.3E-42 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS01160 e6c1af58a06160fc94e702b4ca64be72 183 Pfam PF00881 Nitroreductase family 9 161 6.4E-27 T 10-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 RG49_RS01160 e6c1af58a06160fc94e702b4ca64be72 183 SUPERFAMILY SSF55469 1 168 1.44E-40 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS01160 e6c1af58a06160fc94e702b4ca64be72 183 PIRSF PIRSF000232 1 182 7.4E-71 T 10-03-2017 IPR026021 Putative NAD(P)H nitroreductase YdjA-like RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 Gene3D G3DSA:3.50.30.10 133 255 3.0E-42 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 2.2E-22 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 10-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 541 5.7E-127 T 10-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 PIRSF PIRSF000732 1 574 1.4E-218 T 10-03-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 SUPERFAMILY SSF52009 125 246 4.58E-37 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 10-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 566 6.6E-274 T 10-03-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 SUPERFAMILY SSF47831 23 143 3.27E-34 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 126 5.5E-30 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 Gene3D G3DSA:1.10.274.10 23 132 1.2E-39 T 10-03-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 Gene3D G3DSA:3.20.20.60 256 572 7.1E-116 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 3.5E-31 T 10-03-2017 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 3.5E-31 T 10-03-2017 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 3.5E-31 T 10-03-2017 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 3.5E-31 T 10-03-2017 RG49_RS23045 91bd43f5ae683b80ea757a9c967b9398 575 SUPERFAMILY SSF51621 249 549 2.54E-110 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 SMART SM00861 591 784 1.6E-65 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 50 2.0E-15 T 10-03-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 788 930 3.0E-54 T 10-03-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 SUPERFAMILY SSF52518 575 791 4.04E-52 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 SUPERFAMILY SSF52518 121 546 8.1E-89 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 Gene3D G3DSA:3.40.50.970 592 787 3.1E-26 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 PIRSF PIRSF000157 1 932 0.0 T 10-03-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 Gene3D G3DSA:3.40.50.970 162 550 6.3E-79 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 Pfam PF02779 Transketolase, pyrimidine binding domain 591 785 4.6E-67 T 10-03-2017 IPR005475 Transketolase-like, pyrimidine-binding domain RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 Pfam PF00676 Dehydrogenase E1 component 218 511 1.1E-48 T 10-03-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 RG49_RS07425 5cf06ce62b9e2618a775454fd37dbb54 933 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 14 930 0.0 T 10-03-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 SUPERFAMILY SSF50249 67 145 8.01E-17 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 SUPERFAMILY SSF50249 644 724 1.5E-22 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 SUPERFAMILY SSF50249 221 641 2.46E-144 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 SUPERFAMILY SSF50249 138 235 1.03E-14 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 Pfam PF08461 Ribonuclease R winged-helix domain 23 83 3.4E-13 T 10-03-2017 IPR013668 Ribonuclease R winged-helix domain RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 Pfam PF00773 RNB domain 260 587 1.2E-111 T 10-03-2017 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 SMART SM00357 86 145 2.1E-16 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 Gene3D G3DSA:2.40.50.140 644 734 1.7E-23 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 Pfam PF08206 Ribonuclease B OB domain 87 144 4.2E-22 T 10-03-2017 IPR013223 Ribonuclease B, N-terminal OB domain RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 Pfam PF08206 Ribonuclease B OB domain 158 213 8.4E-5 T 10-03-2017 IPR013223 Ribonuclease B, N-terminal OB domain RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 ProSitePatterns PS01175 Ribonuclease II family signature. 555 579 - T 10-03-2017 IPR022966 Ribonuclease II/R, conserved site RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 67 725 9.1E-294 T 10-03-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 TIGRFAM TIGR02063 RNase_R: ribonuclease R 19 725 1.7E-290 T 10-03-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 SMART SM00955 260 588 5.0E-188 T 10-03-2017 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 Pfam PF00575 S1 RNA binding domain 641 724 2.1E-20 T 10-03-2017 IPR003029 S1 domain GO:0003676 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 Hamap MF_01895 Ribonuclease R [rnr]. 38 725 58.121 T 10-03-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 RG49_RS13020 cf7b4c0c5e3e45edc0de4e6a56a14bee 813 SMART SM00316 642 725 5.2E-17 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS18540 982b6951642d939d01a656f871b7877f 793 Pfam PF13953 PapC C-terminal domain 715 777 3.0E-10 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS18540 982b6951642d939d01a656f871b7877f 793 Pfam PF00577 Outer membrane usher protein 176 706 3.3E-143 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18540 982b6951642d939d01a656f871b7877f 793 SUPERFAMILY SSF141729 29 135 1.31E-9 T 10-03-2017 RG49_RS18540 982b6951642d939d01a656f871b7877f 793 Pfam PF13954 PapC N-terminal domain 47 159 1.2E-12 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS18540 982b6951642d939d01a656f871b7877f 793 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 284 294 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS08965 b46df98f7bf34d27b07a251aa7723c38 491 SUPERFAMILY SSF103473 10 403 1.57E-42 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS08965 b46df98f7bf34d27b07a251aa7723c38 491 Gene3D G3DSA:1.20.1250.20 17 199 2.9E-16 T 10-03-2017 RG49_RS08965 b46df98f7bf34d27b07a251aa7723c38 491 Pfam PF07690 Major Facilitator Superfamily 17 366 1.9E-31 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS08965 b46df98f7bf34d27b07a251aa7723c38 491 Gene3D G3DSA:1.20.1250.20 215 405 1.1E-12 T 10-03-2017 RG49_RS08965 b46df98f7bf34d27b07a251aa7723c38 491 TIGRFAM TIGR00901 2A0125: AmpG-like permease 25 363 3.0E-128 T 10-03-2017 IPR004752 AmpG-like permease/Acetyl-coenzyme A transporter 1 GO:0016020 Reactome: R-HSA-425397|Reactome: R-HSA-5619061 RG49_RS05200 211eeaac246f953b67ca2ccd0477fe3b 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 16.352 T 10-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS05200 211eeaac246f953b67ca2ccd0477fe3b 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.2E-18 T 10-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS05200 211eeaac246f953b67ca2ccd0477fe3b 57 Pfam PF01783 Ribosomal L32p protein family 2 57 1.9E-19 T 10-03-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS05200 211eeaac246f953b67ca2ccd0477fe3b 57 SUPERFAMILY SSF57829 2 55 1.53E-18 T 10-03-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 Gene3D G3DSA:1.10.357.10 54 222 1.3E-74 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.4E-5 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.4E-5 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 SUPERFAMILY SSF46689 4 82 5.64E-19 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 58 - T 10-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 SUPERFAMILY SSF48498 90 219 2.13E-36 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 Pfam PF09209 Domain of unknown function (DUF1956) 96 218 2.1E-37 T 10-03-2017 IPR015292 Transcription regulator YbiH, C-terminal RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 Gene3D G3DSA:1.10.10.60 4 53 5.9E-21 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS07050 a3b73e2913325f8203492988cbe7570e 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.0E-13 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS05910 c72ccfd5cce3382ae775701ab1be4741 148 Pfam PF03733 Inner membrane component domain 4 53 3.2E-9 T 10-03-2017 IPR005185 Inner membrane component domain RG49_RS05910 c72ccfd5cce3382ae775701ab1be4741 148 Pfam PF03733 Inner membrane component domain 77 127 6.2E-17 T 10-03-2017 IPR005185 Inner membrane component domain RG49_RS05910 c72ccfd5cce3382ae775701ab1be4741 148 PIRSF PIRSF028777 1 139 2.8E-54 T 10-03-2017 IPR031308 Uncharacterised conserved protein UCP028777 RG49_RS01800 7ef72b0bab2aa4fe67742c1012ed305f 199 Gene3D G3DSA:1.10.357.10 8 194 4.4E-37 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS01800 7ef72b0bab2aa4fe67742c1012ed305f 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 54 2.4E-10 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS01800 7ef72b0bab2aa4fe67742c1012ed305f 199 SUPERFAMILY SSF48498 81 194 2.36E-23 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS01800 7ef72b0bab2aa4fe67742c1012ed305f 199 SUPERFAMILY SSF46689 7 78 1.85E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01800 7ef72b0bab2aa4fe67742c1012ed305f 199 Pfam PF16925 Bacterial transcriptional repressor C-terminal 84 189 2.3E-10 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS16285 abfb562220e95ca85a1426aeaa09317d 357 Gene3D G3DSA:3.40.50.2000 48 178 1.7E-8 T 10-03-2017 RG49_RS16285 abfb562220e95ca85a1426aeaa09317d 357 Gene3D G3DSA:3.40.50.2000 208 332 2.1E-10 T 10-03-2017 RG49_RS16285 abfb562220e95ca85a1426aeaa09317d 357 SUPERFAMILY SSF53756 42 350 4.93E-37 T 10-03-2017 RG49_RS16285 abfb562220e95ca85a1426aeaa09317d 357 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 274 331 1.2E-6 T 10-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 RG49_RS22890 0258db62944cfdf2ec2a4525305a48dc 95 Gene3D G3DSA:2.40.50.220 1 95 5.9E-35 T 10-03-2017 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml RG49_RS22890 0258db62944cfdf2ec2a4525305a48dc 95 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 83 1.4E-29 T 10-03-2017 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml RG49_RS22890 0258db62944cfdf2ec2a4525305a48dc 95 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 11 83 7.0E-37 T 10-03-2017 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml RG49_RS22890 0258db62944cfdf2ec2a4525305a48dc 95 SUPERFAMILY SSF159133 1 94 1.44E-30 T 10-03-2017 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 PRINTS PR00618 DksA/TraR zinc finger signature 126 138 9.9E-5 T 10-03-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 PRINTS PR00618 DksA/TraR zinc finger signature 114 125 9.9E-5 T 10-03-2017 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 SUPERFAMILY SSF109635 9 109 1.07E-37 T 10-03-2017 RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 110 143 3.0E-10 T 10-03-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 SUPERFAMILY SSF57716 111 149 4.56E-10 T 10-03-2017 RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 32 140 1.7E-51 T 10-03-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 28 150 30.333 T 10-03-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 RG49_RS11105 5492ee991adc2f4a849470a45e6b2141 151 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 114 138 - T 10-03-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site RG49_RS19665 aa7c0905c8694c90f6e72488c504e003 245 SUPERFAMILY SSF69593 2 240 3.53E-62 T 10-03-2017 RG49_RS19665 aa7c0905c8694c90f6e72488c504e003 245 Pfam PF01553 Acyltransferase 53 180 2.7E-32 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS19665 aa7c0905c8694c90f6e72488c504e003 245 Gene3D G3DSA:3.40.1130.10 64 233 3.7E-16 T 10-03-2017 RG49_RS19665 aa7c0905c8694c90f6e72488c504e003 245 SMART SM00563 67 182 2.0E-39 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS19665 aa7c0905c8694c90f6e72488c504e003 245 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 180 4.7E-52 T 10-03-2017 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 RG49_RS10550 8ed30fa024c83ac35ce6b448a8331891 86 PIRSF PIRSF003108 1 86 2.4E-35 T 10-03-2017 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 RG49_RS10550 8ed30fa024c83ac35ce6b448a8331891 86 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 84 2.6E-24 T 10-03-2017 IPR007337 RelB antitoxin/Antitoxin DinJ RG49_RS10550 8ed30fa024c83ac35ce6b448a8331891 86 Pfam PF04221 RelB antitoxin 4 83 1.0E-31 T 10-03-2017 IPR007337 RelB antitoxin/Antitoxin DinJ RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 SMART SM00357 5 69 3.2E-33 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 PIRSF PIRSF002599 1 69 2.5E-26 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 PRINTS PR00050 Cold shock protein signature 6 21 1.8E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 PRINTS PR00050 Cold shock protein signature 27 36 1.8E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 PRINTS PR00050 Cold shock protein signature 42 60 1.8E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 Gene3D G3DSA:2.40.50.140 4 67 1.6E-32 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 1.4E-33 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS07995 a681313ba1313404e2556ff70a8ea5db 69 SUPERFAMILY SSF50249 3 68 5.9E-26 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS08620 78e737f41dea33e1d1e828d78a1f9822 225 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS08620 78e737f41dea33e1d1e828d78a1f9822 225 SMART SM00382 32 213 5.8E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS08620 78e737f41dea33e1d1e828d78a1f9822 225 Gene3D G3DSA:3.40.50.300 5 219 5.7E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08620 78e737f41dea33e1d1e828d78a1f9822 225 Pfam PF00005 ABC transporter 23 166 3.3E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS08620 78e737f41dea33e1d1e828d78a1f9822 225 SUPERFAMILY SSF52540 5 211 5.33E-55 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 538 6.9E-48 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 SUPERFAMILY SSF52518 10 185 1.39E-59 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 14 561 4.1E-202 T 10-03-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 334 1.7E-44 T 10-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 427 446 - T 10-03-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 178 3.6E-58 T 10-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 Gene3D G3DSA:3.40.50.970 362 560 2.7E-70 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 SUPERFAMILY SSF52467 165 361 6.2E-57 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 SUPERFAMILY SSF52518 366 560 8.5E-66 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 Gene3D G3DSA:3.40.50.1220 196 358 3.0E-62 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS15895 1676966fbe4eaf4797618b064ce9d92d 562 Gene3D G3DSA:3.40.50.970 12 185 1.1E-72 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS24895 6e672686ca28e852b72ee0f6eaa2a461 162 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 117 145 - T 10-03-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 RG49_RS24895 6e672686ca28e852b72ee0f6eaa2a461 162 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 141 2.9E-8 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS24895 6e672686ca28e852b72ee0f6eaa2a461 162 TIGRFAM TIGR04016 WcaB: colanic acid biosynthesis acetyltransferase WcaB 17 162 9.8E-97 T 10-03-2017 IPR024027 Colanic acid biosynthesis, acetyltransferase, WcaB GO:0016747 RG49_RS24895 6e672686ca28e852b72ee0f6eaa2a461 162 Gene3D G3DSA:2.160.10.10 60 159 2.2E-24 T 10-03-2017 RG49_RS24895 6e672686ca28e852b72ee0f6eaa2a461 162 PIRSF PIRSF000441 2 161 1.8E-47 T 10-03-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 RG49_RS24895 6e672686ca28e852b72ee0f6eaa2a461 162 SUPERFAMILY SSF51161 11 158 8.32E-33 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS19885 62d3c40fdb833fe56dea562ee832ad10 576 Pfam PF00501 AMP-binding enzyme 47 467 1.6E-75 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS19885 62d3c40fdb833fe56dea562ee832ad10 576 Gene3D G3DSA:3.30.300.30 460 561 9.9E-23 T 10-03-2017 RG49_RS19885 62d3c40fdb833fe56dea562ee832ad10 576 Gene3D G3DSA:3.40.50.980 188 351 2.3E-31 T 10-03-2017 RG49_RS19885 62d3c40fdb833fe56dea562ee832ad10 576 Gene3D G3DSA:2.30.38.10 387 459 4.4E-17 T 10-03-2017 RG49_RS19885 62d3c40fdb833fe56dea562ee832ad10 576 SUPERFAMILY SSF56801 22 354 1.19E-97 T 10-03-2017 RG49_RS19885 62d3c40fdb833fe56dea562ee832ad10 576 SUPERFAMILY SSF56801 383 564 1.19E-97 T 10-03-2017 RG49_RS19885 62d3c40fdb833fe56dea562ee832ad10 576 Gene3D G3DSA:3.40.50.980 47 187 2.7E-27 T 10-03-2017 RG49_RS21285 f5fbc71507b66a1c6006dbd176413410 248 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 233 2.0E-47 T 10-03-2017 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 RG49_RS21285 f5fbc71507b66a1c6006dbd176413410 248 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 46 3.4E-12 T 10-03-2017 IPR013422 CRISPR-associated protein Cas5, N-terminal RG49_RS21285 f5fbc71507b66a1c6006dbd176413410 248 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 232 2.3E-33 T 10-03-2017 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 RG49_RS13790 306f2d8456f2882e0cbc9d450ca77304 235 ProDom PD116985 YJBM ECS5030 1 215 8.0E-111 T 10-03-2017 IPR020404 Protein of unknown function DUF2713 RG49_RS13790 306f2d8456f2882e0cbc9d450ca77304 235 Pfam PF10897 Protein of unknown function (DUF2713) 1 235 3.3E-166 T 10-03-2017 IPR020404 Protein of unknown function DUF2713 RG49_RS04990 2da4f50be2cee1134a6ff6ffaa0c724f 264 SUPERFAMILY SSF161098 3 254 5.98E-56 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04990 2da4f50be2cee1134a6ff6ffaa0c724f 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 253 6.3E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04990 2da4f50be2cee1134a6ff6ffaa0c724f 264 Gene3D G3DSA:1.10.3720.10 5 256 4.7E-56 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04790 00362c4b422b83dc24b4840c36ce5767 231 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 1 103 2.1E-40 T 10-03-2017 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 RG49_RS04790 00362c4b422b83dc24b4840c36ce5767 231 Gene3D G3DSA:2.160.20.70 113 230 4.8E-37 T 10-03-2017 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 RG49_RS04790 00362c4b422b83dc24b4840c36ce5767 231 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 5 231 29.141 T 10-03-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 RG49_RS04790 00362c4b422b83dc24b4840c36ce5767 231 SUPERFAMILY SSF63848 125 230 3.53E-29 T 10-03-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 RG49_RS04790 00362c4b422b83dc24b4840c36ce5767 231 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 6 230 3.5E-71 T 10-03-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 RG49_RS04790 00362c4b422b83dc24b4840c36ce5767 231 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 128 227 5.8E-30 T 10-03-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 RG49_RS22980 bedd03002b8cc4f2c282bc01f83c4ff2 474 Pfam PF02378 Phosphotransferase system, EIIC 120 401 2.7E-41 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS22980 bedd03002b8cc4f2c282bc01f83c4ff2 474 Gene3D G3DSA:3.30.1360.60 7 84 9.2E-21 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS22980 bedd03002b8cc4f2c282bc01f83c4ff2 474 SUPERFAMILY SSF55604 9 82 8.24E-17 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS22980 bedd03002b8cc4f2c282bc01f83c4ff2 474 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 22 39 - T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS22980 bedd03002b8cc4f2c282bc01f83c4ff2 474 Pfam PF00367 phosphotransferase system, EIIB 13 44 1.5E-12 T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS12935 4781572aaf963790cf6fd00e0138473f 154 Gene3D G3DSA:3.40.930.10 6 150 3.8E-52 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS12935 4781572aaf963790cf6fd00e0138473f 154 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 53 69 - T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS12935 4781572aaf963790cf6fd00e0138473f 154 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 148 9.9E-34 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS12935 4781572aaf963790cf6fd00e0138473f 154 SUPERFAMILY SSF55804 7 148 1.96E-36 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS06820 185cd74c8c510d92c0df6803d8f45e1a 371 Pfam PF07995 Glucose / Sorbosone dehydrogenase 34 366 5.6E-131 T 10-03-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 RG49_RS06820 185cd74c8c510d92c0df6803d8f45e1a 371 Gene3D G3DSA:2.120.10.30 11 369 4.8E-105 T 10-03-2017 IPR011042 Six-bladed beta-propeller, TolB-like RG49_RS06820 185cd74c8c510d92c0df6803d8f45e1a 371 SUPERFAMILY SSF50952 20 370 3.79E-42 T 10-03-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 RG49_RS17955 cf609f9af98bf77b57a32eda6a2cb6ec 125 TIGRFAM TIGR01707 gspI: type II secretion system protein I 6 103 1.6E-39 T 10-03-2017 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 RG49_RS17955 cf609f9af98bf77b57a32eda6a2cb6ec 125 Pfam PF02501 Type II secretion system (T2SS), protein I 40 113 9.5E-13 T 10-03-2017 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 RG49_RS17955 cf609f9af98bf77b57a32eda6a2cb6ec 125 Gene3D G3DSA:3.30.1300.30 33 110 1.1E-15 T 10-03-2017 RG49_RS17955 cf609f9af98bf77b57a32eda6a2cb6ec 125 SUPERFAMILY SSF54523 37 105 2.35E-12 T 10-03-2017 RG49_RS17955 cf609f9af98bf77b57a32eda6a2cb6ec 125 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS17955 cf609f9af98bf77b57a32eda6a2cb6ec 125 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 1 25 5.3E-7 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS17955 cf609f9af98bf77b57a32eda6a2cb6ec 125 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.6E-4 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS08910 2477d7b9334dff9d96e1432da8410d67 123 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 55 123 3.2E-38 T 10-03-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain RG49_RS08910 2477d7b9334dff9d96e1432da8410d67 123 Gene3D G3DSA:1.10.150.280 32 116 6.1E-17 T 10-03-2017 RG49_RS08910 2477d7b9334dff9d96e1432da8410d67 123 Pfam PF12836 Helix-hairpin-helix motif 60 118 3.6E-19 T 10-03-2017 RG49_RS08910 2477d7b9334dff9d96e1432da8410d67 123 SUPERFAMILY SSF47781 44 119 9.0E-24 T 10-03-2017 IPR010994 RuvA domain 2-like RG49_RS08910 2477d7b9334dff9d96e1432da8410d67 123 SMART SM00278 71 90 80.0 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS08910 2477d7b9334dff9d96e1432da8410d67 123 SMART SM00278 101 120 5.6 T 10-03-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 SUPERFAMILY SSF55594 1 82 1.44E-27 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 2.6E-31 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.5E-20 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.5E-20 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.5E-20 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 10-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 Gene3D G3DSA:3.30.1340.10 1 83 1.8E-33 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 10-03-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site RG49_RS23050 30f33c2d8de065a355696e4e16a20b30 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 7.6E-28 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 61 95 - T 10-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 Pfam PF01047 MarR family 29 86 1.0E-13 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 SUPERFAMILY SSF46785 4 138 3.39E-30 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 Gene3D G3DSA:1.10.10.10 3 133 1.9E-33 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 4 133 1.3E-60 T 10-03-2017 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 1.5E-7 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 1.5E-7 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 1.5E-7 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS12185 723eabd4d16fed3801e3beb502b62a4e 148 SMART SM00347 22 122 2.4E-31 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 SUPERFAMILY SSF63411 259 452 2.44E-7 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 SUPERFAMILY SSF63411 749 923 1.92E-17 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 SUPERFAMILY SSF63411 35 251 2.27E-45 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 SUPERFAMILY SSF63411 510 732 7.16E-21 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 Pfam PF05193 Peptidase M16 inactive domain 697 862 9.0E-18 T 10-03-2017 IPR007863 Peptidase M16, C-terminal RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 Pfam PF05193 Peptidase M16 inactive domain 207 386 6.0E-25 T 10-03-2017 IPR007863 Peptidase M16, C-terminal RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 Pfam PF00675 Insulinase (Peptidase family M16) 46 203 5.9E-43 T 10-03-2017 IPR011765 Peptidase M16, N-terminal RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 67 90 - T 10-03-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 Gene3D G3DSA:3.30.830.10 263 427 7.7E-5 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 Gene3D G3DSA:3.30.830.10 792 918 6.2E-13 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 Gene3D G3DSA:3.30.830.10 22 262 6.6E-52 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS02850 73d1e0cfccec30c979ec786278ef2f34 931 Gene3D G3DSA:3.30.830.10 507 733 1.0E-17 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS16515 71d04cc50398adc3b074ee63faeaa847 383 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS16515 71d04cc50398adc3b074ee63faeaa847 383 Gene3D G3DSA:1.20.1090.10 185 383 3.6E-76 T 10-03-2017 RG49_RS16515 71d04cc50398adc3b074ee63faeaa847 383 SUPERFAMILY SSF56796 5 382 2.62E-134 T 10-03-2017 RG49_RS16515 71d04cc50398adc3b074ee63faeaa847 383 Gene3D G3DSA:3.40.50.1970 2 184 1.2E-59 T 10-03-2017 RG49_RS16515 71d04cc50398adc3b074ee63faeaa847 383 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 260 280 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS16515 71d04cc50398adc3b074ee63faeaa847 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 375 2.5E-122 T 10-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 Gene3D G3DSA:3.30.1490.20 8 197 2.3E-69 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 SUPERFAMILY SSF56059 7 386 7.89E-110 T 10-03-2017 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 416 427 - T 10-03-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 696 714 - T 10-03-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 Gene3D G3DSA:3.30.470.20 199 357 1.3E-61 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 22 350 6.4E-122 T 10-03-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 PIRSF PIRSF000854 4 792 0.0 T 10-03-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 9 792 0.0 T 10-03-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 SUPERFAMILY SSF51621 467 790 7.59E-96 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 Gene3D G3DSA:3.20.20.60 484 791 7.6E-103 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 SUPERFAMILY SSF52009 350 468 2.22E-35 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 Gene3D G3DSA:3.50.30.10 376 473 1.0E-36 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 482 789 1.0E-59 T 10-03-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 RG49_RS01510 8d98038c6dec8415d1e126fe011fc089 792 Pfam PF00391 PEP-utilising enzyme, mobile domain 386 457 7.5E-27 T 10-03-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 Gene3D G3DSA:3.40.309.10 256 443 2.8E-42 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 Pfam PF00171 Aldehyde dehydrogenase family 9 457 1.9E-116 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 TIGRFAM TIGR03240 arg_catab_astD: succinylglutamate-semialdehyde dehydrogenase 3 486 6.2E-259 T 10-03-2017 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 SUPERFAMILY SSF53720 3 455 6.54E-122 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 Gene3D G3DSA:3.40.605.10 3 255 1.0E-75 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS01265 bc2348a2be2b4467746a881795c40057 492 Hamap MF_01174 N-succinylglutamate 5-semialdehyde dehydrogenase [astD]. 1 486 58.782 T 10-03-2017 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 RG49_RS11495 9f236d51fdd36569883f4b5581d5ad7f 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 247 266 - T 10-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 RG49_RS11495 9f236d51fdd36569883f4b5581d5ad7f 363 SMART SM01329 6 355 6.7E-200 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS11495 9f236d51fdd36569883f4b5581d5ad7f 363 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 6 354 8.2E-173 T 10-03-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 RG49_RS11495 9f236d51fdd36569883f4b5581d5ad7f 363 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 359 51.65 T 10-03-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 RG49_RS11495 9f236d51fdd36569883f4b5581d5ad7f 363 SUPERFAMILY SSF53659 2 360 7.92E-122 T 10-03-2017 RG49_RS11495 9f236d51fdd36569883f4b5581d5ad7f 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 355 1.6E-139 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS11495 9f236d51fdd36569883f4b5581d5ad7f 363 Gene3D G3DSA:3.40.718.10 1 357 3.5E-130 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 Gene3D G3DSA:1.10.357.10 71 197 5.7E-21 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.2E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.2E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 Gene3D G3DSA:1.10.10.60 11 44 2.4E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 SUPERFAMILY SSF46689 10 83 2.74E-18 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 Gene3D G3DSA:1.10.10.60 45 70 8.0E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 1.0E-14 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS12855 a41bd4fab7978013e7d4b07cd2b27904 215 SUPERFAMILY SSF48498 81 207 3.34E-25 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS01060 5eda1cb086170e331a3c413e51100b66 491 SMART SM00267 316 489 1.8E-53 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01060 5eda1cb086170e331a3c413e51100b66 491 Pfam PF17158 Membrane-associated sensor, integral membrane domain 87 321 5.2E-77 T 10-03-2017 IPR033424 Membrane-associated sensor domain RG49_RS01060 5eda1cb086170e331a3c413e51100b66 491 SUPERFAMILY SSF55073 333 488 4.08E-36 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS01060 5eda1cb086170e331a3c413e51100b66 491 Gene3D G3DSA:3.30.70.270 330 488 4.9E-40 T 10-03-2017 RG49_RS01060 5eda1cb086170e331a3c413e51100b66 491 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 326 488 3.3E-36 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01060 5eda1cb086170e331a3c413e51100b66 491 Pfam PF00990 Diguanylate cyclase, GGDEF domain 328 485 3.0E-44 T 10-03-2017 IPR000160 GGDEF domain RG49_RS13860 4b32077a00c6eb3753e64fe6969d58fb 306 Pfam PF07148 Maltose operon periplasmic protein precursor (MalM) 76 209 1.5E-50 T 10-03-2017 IPR010794 Maltose operon periplasmic GO:0008643|GO:0042597 RG49_RS17275 438f40d7216fe0dd6af2818adc8b0051 127 SUPERFAMILY SSF55729 6 120 3.95E-9 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS17275 438f40d7216fe0dd6af2818adc8b0051 127 Gene3D G3DSA:3.40.630.30 27 88 3.5E-7 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS17275 438f40d7216fe0dd6af2818adc8b0051 127 Hamap MF_02018 PanD maturation factor [panM]. 1 126 32.741 T 10-03-2017 IPR032900 PanD maturation factor PanM GO:0015940|GO:0031638 RG49_RS17275 438f40d7216fe0dd6af2818adc8b0051 127 Pfam PF12568 Acetyltransferase (GNAT) domain 2 125 3.7E-50 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS22925 bb6eda21bf5678a5f5a8e3a476a31794 295 PIRSF PIRSF018982 46 295 4.6E-103 T 10-03-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 RG49_RS22925 bb6eda21bf5678a5f5a8e3a476a31794 295 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 57 294 40.838 T 10-03-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 RG49_RS22925 bb6eda21bf5678a5f5a8e3a476a31794 295 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 65 293 9.2E-79 T 10-03-2017 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 RG49_RS08000 0e7f2fe9d16170cc2e898d5c2b55d68e 186 Hamap MF_00837 Lipid A palmitoyltransferase PagP [pagP]. 3 186 43.46 T 10-03-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 RG49_RS08000 0e7f2fe9d16170cc2e898d5c2b55d68e 186 SUPERFAMILY SSF56925 26 186 4.87E-83 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS08000 0e7f2fe9d16170cc2e898d5c2b55d68e 186 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 33 174 8.0E-81 T 10-03-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 RG49_RS08000 0e7f2fe9d16170cc2e898d5c2b55d68e 186 Gene3D G3DSA:2.40.160.20 26 186 1.0E-89 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS08000 0e7f2fe9d16170cc2e898d5c2b55d68e 186 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 37 183 7.4E-67 T 10-03-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 SUPERFAMILY SSF55620 4 221 1.48E-76 T 10-03-2017 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 146 156 - T 10-03-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 98 114 - T 10-03-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 40 220 2.9E-86 T 10-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 Gene3D G3DSA:3.30.1130.10 92 220 6.5E-51 T 10-03-2017 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 36 219 33.594 T 10-03-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 Gene3D G3DSA:1.10.286.10 4 86 3.0E-32 T 10-03-2017 RG49_RS24400 b829dda3ad0de908926a2d546a40a434 222 Pfam PF01227 GTP cyclohydrolase I 41 218 1.9E-62 T 10-03-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 RG49_RS15280 1219b29b57af0f4a060cebd80a3df362 376 SUPERFAMILY SSF53756 2 371 1.04E-142 T 10-03-2017 RG49_RS15280 1219b29b57af0f4a060cebd80a3df362 376 Gene3D G3DSA:3.40.50.2000 2 210 1.6E-89 T 10-03-2017 RG49_RS15280 1219b29b57af0f4a060cebd80a3df362 376 Gene3D G3DSA:3.40.50.2000 211 371 7.0E-68 T 10-03-2017 RG49_RS15280 1219b29b57af0f4a060cebd80a3df362 376 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 370 2.6E-129 T 10-03-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS15280 1219b29b57af0f4a060cebd80a3df362 376 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 372 3.9E-187 T 10-03-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 RG49_RS15280 1219b29b57af0f4a060cebd80a3df362 376 Hamap MF_02028 UDP-N-acetylglucosamine 2-epimerase [wecB]. 16 374 66.377 T 10-03-2017 IPR032892 UDP-N-acetylglucosamine 2-epimerase WecB GO:0008761|GO:0009246 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 RG49_RS23730 c167705fba3c308ba95a407e4b48ea83 167 SUPERFAMILY SSF111069 3 165 3.14E-56 T 10-03-2017 IPR015068 Protein of unknown function DUF1877 RG49_RS23730 c167705fba3c308ba95a407e4b48ea83 167 Pfam PF08974 Domain of unknown function (DUF1877) 1 163 1.0E-33 T 10-03-2017 IPR015068 Protein of unknown function DUF1877 RG49_RS23730 c167705fba3c308ba95a407e4b48ea83 167 Gene3D G3DSA:3.40.1760.10 1 166 3.5E-50 T 10-03-2017 IPR015068 Protein of unknown function DUF1877 RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 Gene3D G3DSA:3.40.50.1220 195 337 1.2E-40 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 Gene3D G3DSA:3.40.50.970 362 549 1.0E-51 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 SUPERFAMILY SSF52518 369 547 6.07E-40 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 6 559 0.0 T 10-03-2017 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696 RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 178 4.9E-47 T 10-03-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 SUPERFAMILY SSF52518 7 184 8.1E-48 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 202 327 1.2E-32 T 10-03-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 SUPERFAMILY SSF52467 165 339 8.59E-37 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 Gene3D G3DSA:3.40.50.970 8 180 1.5E-50 T 10-03-2017 IPR029061 Thiamin diphosphate-binding fold RG49_RS23285 77ee9dd7abd037d9298ee614cd78d715 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 402 540 1.4E-24 T 10-03-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 RG49_RS00175 f418cde13386d5853dfd2461fe0e672c 121 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 25 93 3.3E-23 T 10-03-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 RG49_RS00175 f418cde13386d5853dfd2461fe0e672c 121 Pfam PF04347 Flagellar biosynthesis protein, FliO 37 116 1.7E-19 T 10-03-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 RG49_RS24985 561e9c4743b43ae16d0d08a12f2f285e 331 SUPERFAMILY SSF51735 287 316 4.1E-56 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24985 561e9c4743b43ae16d0d08a12f2f285e 331 SUPERFAMILY SSF51735 3 258 4.1E-56 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24985 561e9c4743b43ae16d0d08a12f2f285e 331 Gene3D G3DSA:3.40.50.720 4 314 7.4E-51 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24985 561e9c4743b43ae16d0d08a12f2f285e 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 222 1.4E-28 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS14505 24d4383590b10e541924f1108f82f3ab 248 SUPERFAMILY SSF63380 3 100 5.91E-26 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS14505 24d4383590b10e541924f1108f82f3ab 248 Gene3D G3DSA:3.40.50.80 97 248 1.1E-47 T 10-03-2017 RG49_RS14505 24d4383590b10e541924f1108f82f3ab 248 Pfam PF00970 Oxidoreductase FAD-binding domain 18 90 2.4E-8 T 10-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 RG49_RS14505 24d4383590b10e541924f1108f82f3ab 248 SUPERFAMILY SSF52343 102 248 1.44E-38 T 10-03-2017 RG49_RS14505 24d4383590b10e541924f1108f82f3ab 248 Pfam PF00175 Oxidoreductase NAD-binding domain 111 222 9.9E-20 T 10-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 RG49_RS14505 24d4383590b10e541924f1108f82f3ab 248 Gene3D G3DSA:2.40.30.10 2 96 3.8E-33 T 10-03-2017 RG49_RS08185 a7ee28a873f9a0ac50b351dd1d77370b 334 Pfam PF01032 FecCD transport family 19 328 4.7E-90 T 10-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 RG49_RS08185 a7ee28a873f9a0ac50b351dd1d77370b 334 SUPERFAMILY SSF81345 9 328 7.72E-75 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS08185 a7ee28a873f9a0ac50b351dd1d77370b 334 Gene3D G3DSA:1.10.3470.10 10 331 7.9E-97 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS13530 d4a5ef41f015a8393ca21129d4a09bca 149 SUPERFAMILY SSF89623 2 145 1.44E-57 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS13530 d4a5ef41f015a8393ca21129d4a09bca 149 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 3 145 2.8E-77 T 10-03-2017 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 RG49_RS13530 d4a5ef41f015a8393ca21129d4a09bca 149 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 4 146 1.5E-63 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS13530 d4a5ef41f015a8393ca21129d4a09bca 149 Gene3D G3DSA:3.40.1400.10 2 148 1.2E-62 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS13530 d4a5ef41f015a8393ca21129d4a09bca 149 Pfam PF02502 Ribose/Galactose Isomerase 4 141 3.0E-54 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS13530 d4a5ef41f015a8393ca21129d4a09bca 149 PIRSF PIRSF005384 2 148 1.2E-60 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS13135 b769f71fc2a0dea781692be3b2f8b79a 500 PIRSF PIRSF006060 1 500 1.3E-66 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS13135 b769f71fc2a0dea781692be3b2f8b79a 500 Pfam PF13520 Amino acid permease 9 467 8.4E-28 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS09155 468f2bf33d7d39ed82ad3a949cae929c 302 Gene3D G3DSA:3.30.420.40 132 280 1.1E-48 T 10-03-2017 RG49_RS09155 468f2bf33d7d39ed82ad3a949cae929c 302 Gene3D G3DSA:3.30.420.40 2 131 2.6E-37 T 10-03-2017 RG49_RS09155 468f2bf33d7d39ed82ad3a949cae929c 302 Pfam PF00480 ROK family 3 301 1.3E-100 T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS09155 468f2bf33d7d39ed82ad3a949cae929c 302 ProSitePatterns PS01125 ROK family signature. 130 157 - T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS09155 468f2bf33d7d39ed82ad3a949cae929c 302 SUPERFAMILY SSF53067 3 300 3.81E-62 T 10-03-2017 RG49_RS20230 e9173a627d8ab274d59a2d0af31af9d0 425 SUPERFAMILY SSF50129 3 188 2.6E-23 T 10-03-2017 IPR011032 GroES-like RG49_RS20230 e9173a627d8ab274d59a2d0af31af9d0 425 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 97 8.1E-7 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS20230 e9173a627d8ab274d59a2d0af31af9d0 425 SUPERFAMILY SSF51735 157 336 2.63E-19 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20230 e9173a627d8ab274d59a2d0af31af9d0 425 Gene3D G3DSA:3.40.50.720 181 314 2.0E-21 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20230 e9173a627d8ab274d59a2d0af31af9d0 425 Gene3D G3DSA:3.90.180.10 4 180 1.7E-15 T 10-03-2017 IPR011032 GroES-like RG49_RS20230 e9173a627d8ab274d59a2d0af31af9d0 425 Pfam PF00107 Zinc-binding dehydrogenase 186 329 4.2E-19 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 5.3E-21 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 6.2E-6 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 6.2E-6 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 SUPERFAMILY SSF47413 3 60 2.13E-16 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 10-03-2017 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 SUPERFAMILY SSF53822 63 314 2.72E-60 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 Gene3D G3DSA:3.40.50.2300 54 174 2.8E-19 T 10-03-2017 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 SMART SM00354 4 74 5.3E-33 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 TIGRFAM TIGR02405 trehalos_R_Ecol: trehalose operon repressor 4 314 1.8E-178 T 10-03-2017 IPR012771 Trehalose operon repressor GO:0003677|GO:0005991|GO:0045892 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 Gene3D G3DSA:3.40.50.2300 175 279 4.5E-42 T 10-03-2017 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 Pfam PF13377 Periplasmic binding protein-like domain 168 312 2.7E-19 T 10-03-2017 RG49_RS12685 e300e389c92535b2ab4d64bd780f0a09 315 Gene3D G3DSA:1.10.260.40 3 53 4.3E-23 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS22315 dcfc4b075be45d8d8d4d72d556b4bdb7 417 PIRSF PIRSF000412 1 417 5.3E-177 T 10-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 RG49_RS22315 dcfc4b075be45d8d8d4d72d556b4bdb7 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 53.473 T 10-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 RG49_RS22315 dcfc4b075be45d8d8d4d72d556b4bdb7 417 Gene3D G3DSA:3.40.640.10 37 285 5.2E-111 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS22315 dcfc4b075be45d8d8d4d72d556b4bdb7 417 Gene3D G3DSA:3.90.1150.10 286 416 1.5E-56 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS22315 dcfc4b075be45d8d8d4d72d556b4bdb7 417 SUPERFAMILY SSF53383 6 416 2.45E-187 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS22315 dcfc4b075be45d8d8d4d72d556b4bdb7 417 Pfam PF00464 Serine hydroxymethyltransferase 8 386 5.0E-192 T 10-03-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 RG49_RS22315 dcfc4b075be45d8d8d4d72d556b4bdb7 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 10-03-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 197 0.0013 T 10-03-2017 RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 7.3E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 7.3E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 7.3E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 7.3E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 7.3E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 7.3E-23 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 Gene3D G3DSA:3.40.50.720 5 246 3.6E-68 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 Pfam PF00106 short chain dehydrogenase 14 208 1.4E-54 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS04230 300e549f11fdd41c0c9fcd5e849be56e 252 SUPERFAMILY SSF51735 10 243 3.59E-62 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04425 0b0bf4f1305f9216153bfac86a8062a8 302 SUPERFAMILY SSF53448 9 291 1.04E-62 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS04425 0b0bf4f1305f9216153bfac86a8062a8 302 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 275 2.8E-116 T 10-03-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 RG49_RS04425 0b0bf4f1305f9216153bfac86a8062a8 302 Pfam PF00483 Nucleotidyl transferase 10 276 1.9E-25 T 10-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 RG49_RS04425 0b0bf4f1305f9216153bfac86a8062a8 302 Gene3D G3DSA:3.90.550.10 9 281 1.3E-69 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS17700 2ce55d72c9a96988a6b81716954a8bbd 117 Pfam PF10941 Protein of unknown function DUF2620 2 116 3.7E-49 T 10-03-2017 IPR021238 Protein of unknown function DUF2620 RG49_RS17700 2ce55d72c9a96988a6b81716954a8bbd 117 Gene3D G3DSA:3.40.1400.10 29 62 7.9E-4 T 10-03-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 RG49_RS08525 1789572b041dafe54ac987870d68db11 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 2.8E-47 T 10-03-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 RG49_RS08525 1789572b041dafe54ac987870d68db11 292 PIRSF PIRSF000103 1 291 1.9E-71 T 10-03-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS08525 1789572b041dafe54ac987870d68db11 292 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 2 291 5.5E-156 T 10-03-2017 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 RG49_RS08525 1789572b041dafe54ac987870d68db11 292 Gene3D G3DSA:3.40.50.720 1 161 1.0E-55 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08525 1789572b041dafe54ac987870d68db11 292 SUPERFAMILY SSF51735 1 160 3.29E-46 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08525 1789572b041dafe54ac987870d68db11 292 Gene3D G3DSA:1.10.1040.10 163 290 4.8E-39 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS08525 1789572b041dafe54ac987870d68db11 292 SUPERFAMILY SSF48179 162 289 3.51E-34 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS08525 1789572b041dafe54ac987870d68db11 292 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 10-03-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 RG49_RS08525 1789572b041dafe54ac987870d68db11 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 283 1.5E-36 T 10-03-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 RG49_RS03650 ee58d986532073ef82cbd529776ee9b9 199 Pfam PF07105 Protein of unknown function (DUF1367) 1 198 1.4E-86 T 10-03-2017 IPR009797 Protein of unknown function DUF1367 RG49_RS08500 9653e1d8690b5d25bdda3e247f40cca6 261 SUPERFAMILY SSF51182 11 261 5.54E-69 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS08500 9653e1d8690b5d25bdda3e247f40cca6 261 Pfam PF07883 Cupin domain 184 230 2.7E-7 T 10-03-2017 IPR013096 Cupin 2, conserved barrel RG49_RS08500 9653e1d8690b5d25bdda3e247f40cca6 261 Gene3D G3DSA:2.60.120.10 2 260 7.3E-101 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS08500 9653e1d8690b5d25bdda3e247f40cca6 261 Pfam PF05899 Protein of unknown function (DUF861) 56 130 4.6E-10 T 10-03-2017 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 RG49_RS08500 9653e1d8690b5d25bdda3e247f40cca6 261 TIGRFAM TIGR03214 ura-cupin: putative allantoin catabolism protein 3 260 2.4E-115 T 10-03-2017 IPR017627 Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 RG49_RS21360 4234d7b268b94820b26c4a45b8a10d98 379 Gene3D G3DSA:3.10.350.10 121 165 6.7E-12 T 10-03-2017 IPR018392 LysM domain RG49_RS21360 4234d7b268b94820b26c4a45b8a10d98 379 Pfam PF01551 Peptidase family M23 279 372 1.2E-31 T 10-03-2017 IPR016047 Peptidase M23 RG49_RS21360 4234d7b268b94820b26c4a45b8a10d98 379 Pfam PF01476 LysM domain 123 165 2.2E-10 T 10-03-2017 IPR018392 LysM domain RG49_RS21360 4234d7b268b94820b26c4a45b8a10d98 379 Gene3D G3DSA:2.70.70.10 244 377 4.1E-42 T 10-03-2017 RG49_RS21360 4234d7b268b94820b26c4a45b8a10d98 379 SMART SM00257 122 166 9.3E-12 T 10-03-2017 IPR018392 LysM domain RG49_RS21360 4234d7b268b94820b26c4a45b8a10d98 379 SUPERFAMILY SSF51261 122 376 1.36E-53 T 10-03-2017 IPR011055 Duplicated hybrid motif RG49_RS13220 443338159b9dde7db20435418ba54934 418 Pfam PF13520 Amino acid permease 8 366 3.1E-30 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS13220 443338159b9dde7db20435418ba54934 418 PIRSF PIRSF006060 1 411 8.8E-59 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS08060 2f6304267a8833c50e3ed177a80c66b1 268 SUPERFAMILY SSF55895 33 262 3.79E-29 T 10-03-2017 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 RG49_RS08060 2f6304267a8833c50e3ed177a80c66b1 268 Gene3D G3DSA:3.90.730.10 33 263 4.4E-33 T 10-03-2017 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 RG49_RS08060 2f6304267a8833c50e3ed177a80c66b1 268 ProSitePatterns PS00531 Ribonuclease T2 family histidine active site 2. 148 159 - T 10-03-2017 IPR033130 Ribonuclease T2, His active site 2 RG49_RS08060 2f6304267a8833c50e3ed177a80c66b1 268 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 75 82 - T 10-03-2017 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 RG49_RS08060 2f6304267a8833c50e3ed177a80c66b1 268 Pfam PF00445 Ribonuclease T2 family 38 237 1.5E-12 T 10-03-2017 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 RG49_RS18890 9aa82d4890c709acd158573fb5dcfc10 172 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 171 2.4E-70 T 10-03-2017 IPR006286 Peptidase C56, PfpI RG49_RS18890 9aa82d4890c709acd158573fb5dcfc10 172 SUPERFAMILY SSF52317 3 170 1.24E-46 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS18890 9aa82d4890c709acd158573fb5dcfc10 172 Pfam PF01965 DJ-1/PfpI family 3 167 7.6E-56 T 10-03-2017 IPR002818 DJ-1/PfpI RG49_RS18890 9aa82d4890c709acd158573fb5dcfc10 172 Gene3D G3DSA:3.40.50.880 1 170 2.5E-52 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS07640 9d77c70a533b14ea06ac555c8f2a2c77 439 TIGRFAM TIGR04299 antiport_PotE: putrescine-ornithine antiporter 4 433 6.0E-257 T 10-03-2017 IPR027566 Putrescine-ornithine antiporter GO:0015496|GO:0015822|GO:0015847 RG49_RS07640 9d77c70a533b14ea06ac555c8f2a2c77 439 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 1 432 1.7E-153 T 10-03-2017 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 RG49_RS07640 9d77c70a533b14ea06ac555c8f2a2c77 439 Pfam PF13520 Amino acid permease 10 408 1.4E-48 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS07640 9d77c70a533b14ea06ac555c8f2a2c77 439 PIRSF PIRSF006060 1 437 6.1E-48 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS11605 1cfadfa6ee50881af75c0c606a5c991a 329 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 321 3.0E-110 T 10-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS11605 1cfadfa6ee50881af75c0c606a5c991a 329 SUPERFAMILY SSF53659 5 327 8.8E-118 T 10-03-2017 RG49_RS11605 1cfadfa6ee50881af75c0c606a5c991a 329 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 3 325 36.652 T 10-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS11605 1cfadfa6ee50881af75c0c606a5c991a 329 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 324 8.0E-132 T 10-03-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS11605 1cfadfa6ee50881af75c0c606a5c991a 329 Gene3D G3DSA:3.40.718.10 3 327 1.9E-139 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS14610 2b6a6bf328ca34c2c705db6cb7c71a8d 344 Pfam PF06379 L-rhamnose-proton symport protein (RhaT) 1 343 7.9E-218 T 10-03-2017 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 RG49_RS14610 2b6a6bf328ca34c2c705db6cb7c71a8d 344 Hamap MF_01532 L-rhamnose-proton symporter [rhaT]. 1 344 46.432 T 10-03-2017 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 RG49_RS14610 2b6a6bf328ca34c2c705db6cb7c71a8d 344 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 7 342 8.7E-115 T 10-03-2017 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 RG49_RS12965 604c1960ad8625228c6885656109ff24 109 Gene3D G3DSA:3.30.1660.10 43 109 1.6E-14 T 10-03-2017 IPR025543 Dodecin-like RG49_RS12965 604c1960ad8625228c6885656109ff24 109 SUPERFAMILY SSF159871 11 108 5.75E-19 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS12965 604c1960ad8625228c6885656109ff24 109 Pfam PF07338 Protein of unknown function (DUF1471) 53 108 3.4E-15 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 Gene3D G3DSA:3.40.1190.20 37 309 5.9E-86 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 SUPERFAMILY SSF53613 7 290 1.87E-69 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 5 308 1.9E-101 T 10-03-2017 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 Pfam PF00294 pfkB family carbohydrate kinase 14 293 1.9E-68 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 5 308 5.5E-99 T 10-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 RG49_RS24315 5648dbdd01a92664ee65d6337de4ceed 312 PIRSF PIRSF000535 2 311 7.9E-119 T 10-03-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 SUPERFAMILY SSF55874 414 551 1.31E-18 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 456 552 8.3E-7 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 Pfam PF07694 5TMR of 5TMR-LYT 29 192 3.9E-43 T 10-03-2017 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 SMART SM00387 452 554 3.5E-9 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 Pfam PF06580 Histidine kinase 359 438 1.1E-24 T 10-03-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 Gene3D G3DSA:3.30.450.40 293 348 1.6E-4 T 10-03-2017 IPR029016 GAF domain-like RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 Gene3D G3DSA:3.30.565.10 411 553 2.2E-17 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 SUPERFAMILY SSF55781 226 345 4.21E-8 T 10-03-2017 IPR029016 GAF domain-like RG49_RS23240 e358aa4e86398a460782239d4e7a5955 565 Pfam PF01590 GAF domain 228 346 1.8E-4 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS12600 4c7f4d37ee5f227c696235bc2b2d9035 147 Gene3D G3DSA:3.40.50.10110 1 144 1.1E-52 T 10-03-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 RG49_RS12600 4c7f4d37ee5f227c696235bc2b2d9035 147 SUPERFAMILY SSF102400 1 145 3.53E-47 T 10-03-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 RG49_RS12600 4c7f4d37ee5f227c696235bc2b2d9035 147 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 141 4.1E-39 T 10-03-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 RG49_RS21940 c834d0ff0d080dbf0afeaf9e7d14e549 96 Gene3D G3DSA:3.10.20.280 4 89 1.1E-37 T 10-03-2017 IPR005346 RnfH protein RG49_RS21940 c834d0ff0d080dbf0afeaf9e7d14e549 96 Hamap MF_00460 Protein RnfH [rnfH]. 5 95 25.828 T 10-03-2017 IPR005346 RnfH protein RG49_RS21940 c834d0ff0d080dbf0afeaf9e7d14e549 96 SUPERFAMILY SSF54285 4 79 6.28E-26 T 10-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp RG49_RS21940 c834d0ff0d080dbf0afeaf9e7d14e549 96 Pfam PF03658 RnfH family Ubiquitin 5 87 2.0E-34 T 10-03-2017 IPR005346 RnfH protein RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 Gene3D G3DSA:3.40.50.300 201 383 7.5E-55 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 Gene3D G3DSA:3.40.50.300 3 159 2.3E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 Hamap MF_00195 GTPase Der [der]. 2 461 39.86 T 10-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 458 9.6E-180 T 10-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 9.1E-10 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 9.1E-10 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 SUPERFAMILY SSF52540 137 167 1.26E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 SUPERFAMILY SSF52540 200 464 1.26E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 157 1.5E-21 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 203 368 3.3E-24 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 SUPERFAMILY SSF52540 4 168 9.85E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 PIRSF PIRSF006485 1 466 1.1E-179 T 10-03-2017 IPR016484 GTP-binding protein EngA GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 378 458 2.2E-26 T 10-03-2017 IPR032859 GTPase Der, C-terminal KH-domain-like RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 Gene3D G3DSA:3.30.300.20 384 459 1.8E-23 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 Pfam PF01926 50S ribosome-binding GTPase 205 322 8.4E-25 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS22515 91ef54ffa17e6a062f64b916b7f842ac 490 Pfam PF01926 50S ribosome-binding GTPase 5 119 6.4E-29 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS18455 0d552860d03d7427ddfb58c6c723f3b7 132 PIRSF PIRSF006318 1 132 1.0E-51 T 10-03-2017 IPR009386 Protein of unknown function DUF1043 RG49_RS18455 0d552860d03d7427ddfb58c6c723f3b7 132 Pfam PF06295 Protein of unknown function (DUF1043) 6 126 5.1E-48 T 10-03-2017 IPR009386 Protein of unknown function DUF1043 RG49_RS00350 a52a7859fbfd934bc77137489798d420 182 Hamap MF_01437 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [pgsA]. 1 182 34.88 T 10-03-2017 IPR023762 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, bacterial GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 RG49_RS00350 a52a7859fbfd934bc77137489798d420 182 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 181 1.6E-66 T 10-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 RG49_RS00350 a52a7859fbfd934bc77137489798d420 182 PIRSF PIRSF000847 1 179 7.2E-43 T 10-03-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 RG49_RS00350 a52a7859fbfd934bc77137489798d420 182 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 71 7.9E-18 T 10-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 RG49_RS00350 a52a7859fbfd934bc77137489798d420 182 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 10-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 SUPERFAMILY SSF51182 25 162 3.56E-15 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 256 272 3.7E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 256 3.7E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 Pfam PF12833 Helix-turn-helix domain 200 273 1.4E-19 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 Gene3D G3DSA:2.60.120.10 26 100 5.3E-13 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 SMART SM00342 189 272 4.2E-26 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 Pfam PF07883 Cupin domain 29 81 5.0E-8 T 10-03-2017 IPR013096 Cupin 2, conserved barrel RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 268 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 Gene3D G3DSA:1.10.10.60 224 274 2.3E-17 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01325 d8d0320c909ab4012575b41505f8932d 280 SUPERFAMILY SSF46689 225 275 1.57E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS19025 cf28abc88718dd7facf01872314fd648 111 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 14 101 3.0E-47 T 10-03-2017 RG49_RS19025 cf28abc88718dd7facf01872314fd648 111 SUPERFAMILY SSF89447 13 39 2.96E-5 T 10-03-2017 RG49_RS19025 cf28abc88718dd7facf01872314fd648 111 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 14 110 2.0E-39 T 10-03-2017 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 RG49_RS03965 7d5b178618d0ce4ad7473530a6323abc 351 SUPERFAMILY SSF55347 138 287 7.52E-23 T 10-03-2017 RG49_RS03965 7d5b178618d0ce4ad7473530a6323abc 351 SUPERFAMILY SSF51735 5 158 2.02E-48 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03965 7d5b178618d0ce4ad7473530a6323abc 351 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 128 1.3E-31 T 10-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 RG49_RS03965 7d5b178618d0ce4ad7473530a6323abc 351 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 249 7.2E-15 T 10-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 RG49_RS03965 7d5b178618d0ce4ad7473530a6323abc 351 Gene3D G3DSA:3.30.360.10 145 346 8.5E-47 T 10-03-2017 RG49_RS03965 7d5b178618d0ce4ad7473530a6323abc 351 Gene3D G3DSA:3.40.50.720 4 144 9.4E-48 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS00625 6628f5412cfb4def4d862c2d7263fa8b 261 SUPERFAMILY SSF81345 3 257 8.63E-42 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS00625 6628f5412cfb4def4d862c2d7263fa8b 261 Pfam PF00950 ABC 3 transport family 2 257 7.1E-89 T 10-03-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 RG49_RS00625 6628f5412cfb4def4d862c2d7263fa8b 261 Gene3D G3DSA:1.10.3470.10 60 259 2.9E-11 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 4.9E-17 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 4.9E-17 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 4.9E-17 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 4.9E-17 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 Gene3D G3DSA:1.20.200.10 120 389 1.4E-88 T 10-03-2017 RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 Pfam PF00206 Lyase 14 312 1.3E-84 T 10-03-2017 IPR022761 Fumarate lyase, N-terminal RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 10-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 Gene3D G3DSA:1.10.275.10 1 119 2.0E-49 T 10-03-2017 IPR024083 Fumarase/histidase, N-terminal RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 1.4E-52 T 10-03-2017 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 455 9.9E-159 T 10-03-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 SUPERFAMILY SSF48557 10 454 1.52E-106 T 10-03-2017 IPR008948 L-Aspartase-like GO:0003824 RG49_RS04950 fb9a8b640c464a4aa7ca8951cb3a41f7 456 Gene3D G3DSA:1.10.40.30 390 445 1.0E-34 T 10-03-2017 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 SUPERFAMILY SSF47413 3 51 7.13E-12 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 6.2E-6 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 6.2E-6 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 SMART SM00354 1 74 9.6E-24 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 SUPERFAMILY SSF53822 76 309 1.72E-40 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 Gene3D G3DSA:3.40.50.2300 171 305 4.4E-35 T 10-03-2017 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 Pfam PF13377 Periplasmic binding protein-like domain 168 326 9.3E-31 T 10-03-2017 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 Gene3D G3DSA:3.40.50.2300 76 170 5.3E-8 T 10-03-2017 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 10-03-2017 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 Gene3D G3DSA:1.10.260.40 1 58 1.2E-19 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS19335 f3727352e1569bc404d406943a74ceb2 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 49 8.4E-18 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS20225 8ce8ec0d6ea47d9d398fe9ac61320dc1 462 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 372 454 3.5E-12 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS20225 8ce8ec0d6ea47d9d398fe9ac61320dc1 462 Pfam PF02378 Phosphotransferase system, EIIC 20 277 5.1E-23 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS20225 8ce8ec0d6ea47d9d398fe9ac61320dc1 462 Gene3D G3DSA:3.40.50.10370 369 461 2.0E-32 T 10-03-2017 IPR029503 Phosphotransferase system EIIB component, mannitol-specific GO:0009401|GO:0022872 RG49_RS20225 8ce8ec0d6ea47d9d398fe9ac61320dc1 462 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 9 344 1.0E-144 T 10-03-2017 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 RG49_RS20225 8ce8ec0d6ea47d9d398fe9ac61320dc1 462 SUPERFAMILY SSF52794 369 459 1.96E-22 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS23845 022b1be73d6845cd620a08416a36917c 180 Pfam PF07437 YfaZ precursor 1 180 4.2E-92 T 10-03-2017 IPR009998 YfaZ RG49_RS23845 022b1be73d6845cd620a08416a36917c 180 Gene3D G3DSA:2.40.160.10 13 180 1.8E-9 T 10-03-2017 IPR023614 Porin domain RG49_RS23845 022b1be73d6845cd620a08416a36917c 180 SUPERFAMILY SSF56925 56 177 2.43E-8 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 SUPERFAMILY SSF52540 139 382 9.46E-75 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 Gene3D G3DSA:3.40.50.300 138 312 2.7E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 Pfam PF00158 Sigma-54 interaction domain 140 306 1.4E-70 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 SUPERFAMILY SSF46689 380 469 5.73E-24 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 SMART SM00448 4 115 1.1E-38 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 466 1.3E-249 T 10-03-2017 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 Gene3D G3DSA:1.10.10.60 399 469 5.0E-24 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 SUPERFAMILY SSF52172 6 185 7.26E-49 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 Gene3D G3DSA:3.40.50.2300 6 132 1.2E-39 T 10-03-2017 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 Gene3D G3DSA:1.10.8.60 313 391 2.0E-24 T 10-03-2017 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 SMART SM00382 160 311 5.6E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 Pfam PF02954 Bacterial regulatory protein, Fis family 427 466 1.9E-15 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 8.0E-11 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 469 8.0E-11 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS14840 2e4923d18ec24bccc33a37b0a1ac41dd 469 Pfam PF00072 Response regulator receiver domain 6 115 5.9E-31 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Pfam PF05193 Peptidase M16 inactive domain 216 394 5.0E-21 T 10-03-2017 IPR007863 Peptidase M16, C-terminal RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Pfam PF05193 Peptidase M16 inactive domain 681 856 2.4E-14 T 10-03-2017 IPR007863 Peptidase M16, C-terminal RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 SUPERFAMILY SSF63411 735 957 7.33E-45 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Gene3D G3DSA:3.30.830.10 30 266 1.4E-63 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 SUPERFAMILY SSF63411 33 261 7.14E-51 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Gene3D G3DSA:3.30.830.10 507 729 3.0E-67 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 SUPERFAMILY SSF63411 504 728 1.47E-48 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 SUPERFAMILY SSF63411 265 502 4.02E-66 T 10-03-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Pfam PF16187 Middle or third domain of peptidase_M16 400 676 2.5E-54 T 10-03-2017 IPR032632 Peptidase M16, middle/third domain RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Gene3D G3DSA:3.30.830.10 730 959 8.5E-61 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 75 98 - T 10-03-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Gene3D G3DSA:3.30.830.10 274 506 9.9E-65 T 10-03-2017 IPR011237 Peptidase M16 domain GO:0046872 RG49_RS20935 9617c6dfd595a41a4f9436331fa5191f 962 Pfam PF00675 Insulinase (Peptidase family M16) 54 191 9.5E-39 T 10-03-2017 IPR011765 Peptidase M16, N-terminal RG49_RS07605 d9f5c128c07ed8306e9eea6fdcdce241 557 Pfam PF03814 Potassium-transporting ATPase A subunit 11 556 7.5E-237 T 10-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 RG49_RS07605 d9f5c128c07ed8306e9eea6fdcdce241 557 PIRSF PIRSF001294 1 557 2.1E-231 T 10-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 RG49_RS07605 d9f5c128c07ed8306e9eea6fdcdce241 557 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 557 34.305 T 10-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 RG49_RS07605 d9f5c128c07ed8306e9eea6fdcdce241 557 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 1 557 7.5E-304 T 10-03-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 RG49_RS20360 3c0f8422c72cb3433a8dc7790148cb5c 192 SUPERFAMILY SSF101327 7 176 1.16E-54 T 10-03-2017 IPR011978 Uncharacterised protein family UPF0149 RG49_RS20360 3c0f8422c72cb3433a8dc7790148cb5c 192 Pfam PF03695 Uncharacterised protein family (UPF0149) 12 176 5.6E-42 T 10-03-2017 IPR011978 Uncharacterised protein family UPF0149 RG49_RS20360 3c0f8422c72cb3433a8dc7790148cb5c 192 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 11 166 2.0E-14 T 10-03-2017 IPR011978 Uncharacterised protein family UPF0149 RG49_RS20360 3c0f8422c72cb3433a8dc7790148cb5c 192 Hamap MF_00346 UPF0149 protein YgfB [ygfB]. 6 190 36.957 T 10-03-2017 IPR011978 Uncharacterised protein family UPF0149 RG49_RS08285 f6969707e14eb556ff9022b77907146d 415 SUPERFAMILY SSF82689 317 395 1.19E-6 T 10-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 RG49_RS08285 f6969707e14eb556ff9022b77907146d 415 Gene3D G3DSA:2.30.30.60 203 252 9.1E-9 T 10-03-2017 RG49_RS08285 f6969707e14eb556ff9022b77907146d 415 Gene3D G3DSA:3.30.70.100 323 389 8.9E-4 T 10-03-2017 RG49_RS08285 f6969707e14eb556ff9022b77907146d 415 Pfam PF00924 Mechanosensitive ion channel 142 396 8.1E-72 T 10-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 RG49_RS08285 f6969707e14eb556ff9022b77907146d 415 SUPERFAMILY SSF50182 187 253 4.58E-12 T 10-03-2017 IPR010920 LSM domain RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 SUPERFAMILY SSF55904 567 708 5.75E-45 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 Gene3D G3DSA:3.90.100.10 587 714 5.4E-39 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 14 124 4.1E-29 T 10-03-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 Gene3D G3DSA:3.40.640.10 130 423 2.1E-100 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 362 376 - T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 SUPERFAMILY SSF53383 130 561 4.7E-106 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 570 700 8.6E-46 T 10-03-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 130 545 5.3E-199 T 10-03-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 Gene3D G3DSA:3.90.1150.10 426 586 1.0E-66 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS13280 b640034e80a937d0aa8b98b1180e4740 715 PIRSF PIRSF009393 1 712 1.3E-287 T 10-03-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 RG49_RS12725 29e4b718b1fbfeb0e8756844d1b25bc0 181 Gene3D G3DSA:1.10.60.30 110 180 2.2E-32 T 10-03-2017 IPR023153 PSPTO4464-like domain RG49_RS12725 29e4b718b1fbfeb0e8756844d1b25bc0 181 PIRSF PIRSF016183 9 181 1.7E-71 T 10-03-2017 IPR006839 Ribosome-associated, YjgA RG49_RS12725 29e4b718b1fbfeb0e8756844d1b25bc0 181 Gene3D G3DSA:1.10.60.30 34 108 4.2E-29 T 10-03-2017 IPR023153 PSPTO4464-like domain RG49_RS12725 29e4b718b1fbfeb0e8756844d1b25bc0 181 SUPERFAMILY SSF158710 35 177 3.27E-51 T 10-03-2017 RG49_RS12725 29e4b718b1fbfeb0e8756844d1b25bc0 181 Pfam PF04751 Protein of unknown function (DUF615) 24 174 5.8E-55 T 10-03-2017 IPR006839 Ribosome-associated, YjgA RG49_RS12725 29e4b718b1fbfeb0e8756844d1b25bc0 181 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 14 178 23.773 T 10-03-2017 IPR006839 Ribosome-associated, YjgA RG49_RS23245 8902fe615cdfe858076263ea63c7a812 412 Gene3D G3DSA:3.90.1150.10 264 395 9.1E-45 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS23245 8902fe615cdfe858076263ea63c7a812 412 Gene3D G3DSA:3.40.640.10 50 263 6.3E-62 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS23245 8902fe615cdfe858076263ea63c7a812 412 SUPERFAMILY SSF53383 10 394 3.54E-107 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS23245 8902fe615cdfe858076263ea63c7a812 412 Pfam PF00155 Aminotransferase class I and II 37 376 2.3E-60 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS23325 3b2370aab3a5230b8ef0eb39924478ff 445 Pfam PF02447 GntP family permease 7 444 9.5E-166 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS23325 3b2370aab3a5230b8ef0eb39924478ff 445 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 445 1.7E-176 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS23325 3b2370aab3a5230b8ef0eb39924478ff 445 PIRSF PIRSF002746 2 445 8.0E-147 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS03665 1fcf65d678609bf0539867f66c7177a9 230 Gene3D G3DSA:3.10.490.10 43 210 1.5E-37 T 10-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like RG49_RS03665 1fcf65d678609bf0539867f66c7177a9 230 Pfam PF04752 ChaC-like protein 48 212 7.3E-39 T 10-03-2017 IPR006840 ChaC-like protein Reactome: R-HSA-174403 RG49_RS03665 1fcf65d678609bf0539867f66c7177a9 230 SUPERFAMILY SSF110857 48 161 2.62E-10 T 10-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1467 1565 7.65E-19 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 539 635 1.75E-17 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00089 955 1049 0.2 T 10-03-2017 IPR022409 PKD/Chitinase domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00089 1486 1578 5.6E-9 T 10-03-2017 IPR022409 PKD/Chitinase domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00089 1073 1153 3.5E-10 T 10-03-2017 IPR022409 PKD/Chitinase domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00089 1591 1671 2.5E-12 T 10-03-2017 IPR022409 PKD/Chitinase domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1360 1459 4.19E-15 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 641 725 1.3E-11 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1361 1459 4.1E-18 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 536 636 2.6E-17 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1562 1668 1.78E-20 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1256 1356 6.54E-11 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 842 938 4.71E-20 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 940 1047 2.55E-20 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1767 1863 5.89E-13 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1148 1250 1.1E-18 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1774 1865 1.2E-16 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1155 1249 9.9E-20 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1467 1562 1.5E-23 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1569 1667 2.8E-22 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1255 1356 6.2E-19 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 948 1046 9.6E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1684 1757 1.1E-15 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 1052 1150 1.7E-24 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF09134 Invasin, domain 3 542 637 7.7E-14 T 10-03-2017 IPR015217 Invasin, domain 3 RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 745 845 2.4E-16 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Gene3D G3DSA:2.60.40.920 846 943 4.9E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 942 1041 3.6E-25 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1564 1664 8.6E-27 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1361 1456 1.1E-23 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1257 1357 4.2E-26 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1777 1858 3.6E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1469 1561 2.5E-28 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1675 1761 1.3E-22 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 852 939 3.5E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 748 838 8.0E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1054 1146 2.3E-27 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF02369 Bacterial Ig-like domain (group 1) 1158 1246 4.4E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1044 1151 3.14E-21 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 1667 1759 1.47E-14 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1256 1356 8.8E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 849 937 2.2E-26 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1366 1457 7.8E-27 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1155 1245 1.7E-26 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1051 1145 1.6E-36 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1569 1663 4.2E-34 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1466 1560 1.6E-35 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 748 840 2.1E-25 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1674 1761 1.3E-21 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 1773 1862 1.9E-26 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SMART SM00634 947 1041 2.1E-32 T 10-03-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 Pfam PF11924 Invasin beta-domain of outer membrane 153 428 9.7E-111 T 10-03-2017 IPR024519 Invasin beta-domain of outer membrane RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 SUPERFAMILY SSF49373 748 845 4.71E-14 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 PRINTS PR01369 Intimin signature 279 294 8.8E-11 T 10-03-2017 IPR003535 Intimin/invasin bacterial adhesion mediator protein GO:0007155 RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 PRINTS PR01369 Intimin signature 308 327 8.8E-11 T 10-03-2017 IPR003535 Intimin/invasin bacterial adhesion mediator protein GO:0007155 RG49_RS25380 cbdac3b799175ea2d221b95964dad48d 1866 PRINTS PR01369 Intimin signature 376 395 8.8E-11 T 10-03-2017 IPR003535 Intimin/invasin bacterial adhesion mediator protein GO:0007155 RG49_RS07540 1f8e5f6ccb931658a7d0407519b276a7 247 Gene3D G3DSA:3.40.1390.30 1 107 1.5E-40 T 10-03-2017 RG49_RS07540 1f8e5f6ccb931658a7d0407519b276a7 247 SUPERFAMILY SSF102705 1 246 4.84E-85 T 10-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 RG49_RS07540 1f8e5f6ccb931658a7d0407519b276a7 247 Gene3D G3DSA:3.40.1390.30 108 214 1.8E-29 T 10-03-2017 RG49_RS07540 1f8e5f6ccb931658a7d0407519b276a7 247 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 234 2.3E-57 T 10-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 RG49_RS07540 1f8e5f6ccb931658a7d0407519b276a7 247 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 246 4.3E-83 T 10-03-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 RG49_RS02565 df3a48ee6cec33ee2e1d9770bc0ac91f 127 Gene3D G3DSA:1.10.10.60 7 62 5.7E-25 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02565 df3a48ee6cec33ee2e1d9770bc0ac91f 127 SMART SM00342 25 108 3.0E-31 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS02565 df3a48ee6cec33ee2e1d9770bc0ac91f 127 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 62 104 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS02565 df3a48ee6cec33ee2e1d9770bc0ac91f 127 Gene3D G3DSA:1.10.10.60 63 125 1.0E-22 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02565 df3a48ee6cec33ee2e1d9770bc0ac91f 127 SUPERFAMILY SSF46689 62 111 4.08E-10 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02565 df3a48ee6cec33ee2e1d9770bc0ac91f 127 SUPERFAMILY SSF46689 10 59 1.03E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02565 df3a48ee6cec33ee2e1d9770bc0ac91f 127 Pfam PF12833 Helix-turn-helix domain 32 108 5.8E-18 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS05920 6361f275c91f2feefb9053d6ca87cca6 209 Gene3D G3DSA:3.30.1460.30 5 107 3.7E-34 T 10-03-2017 IPR007076 TfoX, N-terminal RG49_RS05920 6361f275c91f2feefb9053d6ca87cca6 209 Gene3D G3DSA:1.10.150.20 117 205 2.3E-29 T 10-03-2017 RG49_RS05920 6361f275c91f2feefb9053d6ca87cca6 209 Pfam PF04994 TfoX C-terminal domain 116 194 1.5E-26 T 10-03-2017 IPR007077 TfoX, C-terminal RG49_RS05920 6361f275c91f2feefb9053d6ca87cca6 209 PIRSF PIRSF028788 1 205 9.6E-56 T 10-03-2017 IPR026256 Transcriptional regulator, TfoX/Sxy-type RG49_RS05920 6361f275c91f2feefb9053d6ca87cca6 209 SUPERFAMILY SSF159894 13 107 1.44E-26 T 10-03-2017 RG49_RS05920 6361f275c91f2feefb9053d6ca87cca6 209 Pfam PF04993 TfoX N-terminal domain 14 106 9.1E-26 T 10-03-2017 IPR007076 TfoX, N-terminal RG49_RS02150 cbf9905318382579367a802acc11ae67 236 Pfam PF06788 Uncharacterised protein family (UPF0257) 1 236 1.1E-127 T 10-03-2017 IPR010646 Uncharacterised protein family UPF0257 GO:0005886 RG49_RS02150 cbf9905318382579367a802acc11ae67 236 ProDom PD120112 LIPOPROTEIN YNFC MEMBRANE UPF0257 PRECURSOR PALMITATE SIGNAL INNER 1 236 3.0E-137 T 10-03-2017 IPR010646 Uncharacterised protein family UPF0257 GO:0005886 RG49_RS02150 cbf9905318382579367a802acc11ae67 236 Hamap MF_01065 UPF0257 lipoprotein YnfC [ynfC]. 1 236 68.976 T 10-03-2017 IPR010646 Uncharacterised protein family UPF0257 GO:0005886 RG49_RS19870 137008ad36b71c4feb0917635d824c88 390 Pfam PF00155 Aminotransferase class I and II 44 384 5.0E-54 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS19870 137008ad36b71c4feb0917635d824c88 390 Gene3D G3DSA:3.40.640.10 64 276 1.4E-81 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS19870 137008ad36b71c4feb0917635d824c88 390 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 10-03-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 RG49_RS19870 137008ad36b71c4feb0917635d824c88 390 SUPERFAMILY SSF53383 8 387 3.99E-98 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS19870 137008ad36b71c4feb0917635d824c88 390 Gene3D G3DSA:3.90.1150.10 277 387 4.2E-25 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS19225 a13c3466ab65d56408638a9d2649c78a 127 Pfam PF13721 SecD export protein N-terminal TM region 17 104 5.6E-17 T 10-03-2017 IPR027398 SecD export protein N-terminal TM domain RG49_RS19225 a13c3466ab65d56408638a9d2649c78a 127 Hamap MF_00904 Modulator protein MzrA [mzrA]. 2 116 29.285 T 10-03-2017 IPR026574 Modulator protein MzrA RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 13 49 2.9E-16 T 10-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 104 142 6.9E-16 T 10-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 145 167 0.12 T 10-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 62 98 1.1E-17 T 10-03-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 SUPERFAMILY SSF57783 12 49 2.55E-13 T 10-03-2017 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 SUPERFAMILY SSF57783 60 99 1.46E-12 T 10-03-2017 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 Gene3D G3DSA:3.30.65.10 62 96 1.5E-13 T 10-03-2017 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 Gene3D G3DSA:3.30.65.10 102 136 3.6E-4 T 10-03-2017 RG49_RS18185 061f2c854f71fb2933858f32bac9bd55 180 Gene3D G3DSA:3.30.65.10 14 49 4.4E-15 T 10-03-2017 RG49_RS06325 7685e403ced062aa096db5195bf558e7 72 SUPERFAMILY SSF50249 1 70 5.36E-29 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06325 7685e403ced062aa096db5195bf558e7 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 5.1E-39 T 10-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 RG49_RS06325 7685e403ced062aa096db5195bf558e7 72 Gene3D G3DSA:2.40.50.140 1 71 6.9E-39 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06325 7685e403ced062aa096db5195bf558e7 72 SMART SM00316 4 72 2.8E-7 T 10-03-2017 IPR022967 RNA-binding domain, S1 RG49_RS06325 7685e403ced062aa096db5195bf558e7 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 8.4E-28 T 10-03-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 RG49_RS06325 7685e403ced062aa096db5195bf558e7 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.442 T 10-03-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 RG49_RS17190 b46dc9d776715839552090d863e67590 524 PIRSF PIRSF002741 20 520 2.9E-90 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS17190 b46dc9d776715839552090d863e67590 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 68 433 1.2E-92 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS17190 b46dc9d776715839552090d863e67590 524 Gene3D G3DSA:3.40.190.10 128 281 4.6E-40 T 10-03-2017 RG49_RS17190 b46dc9d776715839552090d863e67590 524 SUPERFAMILY SSF53850 27 517 1.99E-129 T 10-03-2017 RG49_RS17190 b46dc9d776715839552090d863e67590 524 TIGRFAM TIGR02294 nickel_nikA: nickel ABC transporter, nickel/metallophore periplasmic binding protein 22 520 1.1E-253 T 10-03-2017 IPR011980 Periplasmic nickel-binding protein GO:0015675|GO:0016151|GO:0020037 RG49_RS17190 b46dc9d776715839552090d863e67590 524 Gene3D G3DSA:3.10.105.10 282 490 2.8E-48 T 10-03-2017 RG49_RS17190 b46dc9d776715839552090d863e67590 524 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 73 95 - T 10-03-2017 IPR023765 Solute-binding protein family 5, conserved site RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 Gene3D G3DSA:3.40.190.10 31 152 2.5E-24 T 10-03-2017 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 SUPERFAMILY SSF53850 29 395 5.43E-100 T 10-03-2017 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 Pfam PF13416 Bacterial extracellular solute-binding protein 50 343 1.2E-42 T 10-03-2017 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 357 376 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 130 149 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 233 252 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 70 88 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 299 320 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 151 170 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 171 190 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 PRINTS PR00181 Maltose binding protein signature 36 54 9.4E-101 T 10-03-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 Gene3D G3DSA:3.40.190.10 153 322 5.2E-59 T 10-03-2017 RG49_RS13880 cce42a1bc3dba537c63b008bbf8fb026 396 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 133 150 - T 10-03-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 RG49_RS09110 2502d6cf4bbc03565b0eae18159ac0f1 193 Pfam PF04336 Protein of unknown function, DUF479 81 186 5.8E-29 T 10-03-2017 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 RG49_RS09110 2502d6cf4bbc03565b0eae18159ac0f1 193 PIRSF PIRSF011489 1 193 2.0E-86 T 10-03-2017 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 RG49_RS09110 2502d6cf4bbc03565b0eae18159ac0f1 193 Hamap MF_01950 Acyl carrier protein phosphodiesterase [acpH]. 1 193 57.007 T 10-03-2017 IPR023491 Acyl carrier protein phosphodiesterase, gammaproteobacteria GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 PRINTS PR00762 Chloride channel signature 115 134 4.2E-21 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 PRINTS PR00762 Chloride channel signature 165 184 4.2E-21 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 PRINTS PR00762 Chloride channel signature 364 380 4.2E-21 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 PRINTS PR00762 Chloride channel signature 382 401 4.2E-21 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 PRINTS PR00762 Chloride channel signature 329 349 4.2E-21 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 SUPERFAMILY SSF81340 4 426 1.57E-87 T 10-03-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 Hamap MF_01203 Voltage-gated ClC-type chloride channel ClcB [clcB]. 16 425 40.591 T 10-03-2017 IPR023790 Chloride channel, voltage-gated, ClcB GO:0006821|GO:0010447 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 Gene3D G3DSA:1.10.3080.10 11 426 7.5E-73 T 10-03-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 RG49_RS02115 1d5f6d89ac274baf9ce0b7867c65dd1d 430 Pfam PF00654 Voltage gated chloride channel 75 414 3.1E-75 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS14800 78ed185e12a2afaef8109dfa36420f58 230 SUPERFAMILY SSF56935 19 230 8.7E-6 T 10-03-2017 RG49_RS14800 78ed185e12a2afaef8109dfa36420f58 230 Pfam PF06178 Oligogalacturonate-specific porin protein (KdgM) 14 230 8.7E-92 T 10-03-2017 IPR009331 Oligogalacturonate-specific porin RG49_RS14800 78ed185e12a2afaef8109dfa36420f58 230 Gene3D G3DSA:2.40.230.30 23 230 7.7E-61 T 10-03-2017 RG49_RS18180 b04c6c392fe494e9a01eddae341e7995 157 Pfam PF04361 Protein of unknown function (DUF494) 1 157 4.1E-59 T 10-03-2017 IPR007456 Smg RG49_RS18180 b04c6c392fe494e9a01eddae341e7995 157 Hamap MF_00598 Protein Smg [smg]. 1 157 33.393 T 10-03-2017 IPR007456 Smg RG49_RS19030 78261d16ff6656ac479f4550b2ddd7e2 523 SMART SM00858 22 92 5.2E-14 T 10-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 RG49_RS19030 78261d16ff6656ac479f4550b2ddd7e2 523 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 15 523 4.7E-284 T 10-03-2017 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 RG49_RS19030 78261d16ff6656ac479f4550b2ddd7e2 523 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 119 521 3.7E-147 T 10-03-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 RG49_RS19030 78261d16ff6656ac479f4550b2ddd7e2 523 Pfam PF08666 SAF domain 22 91 2.5E-13 T 10-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 RG49_RS19030 78261d16ff6656ac479f4550b2ddd7e2 523 Hamap MF_02031 Galactarate dehydratase (L-threo-forming) [garD]. 2 523 79.757 T 10-03-2017 IPR032893 Galactarate dehydratase (L-threo-forming) GarD, Enterobacteriaceae GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 316 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 30 417 1.7E-146 T 10-03-2017 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 Pfam PF00083 Sugar (and other) transporter 24 221 4.6E-26 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 Pfam PF00083 Sugar (and other) transporter 223 421 6.7E-12 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 SUPERFAMILY SSF103473 18 430 2.35E-64 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 Gene3D G3DSA:1.20.1250.20 240 428 3.7E-18 T 10-03-2017 RG49_RS22100 79418c8d83875c099c912df867d9aa6e 432 Gene3D G3DSA:1.20.1250.20 22 227 3.0E-25 T 10-03-2017 RG49_RS01025 2c3b8950ae2804cb881e39a1162f1c3d 115 Pfam PF04343 Protein of unknown function, DUF488 5 112 1.8E-31 T 10-03-2017 IPR007438 Protein of unknown function DUF488 RG49_RS14385 bfabdd738cc4915d44ddb8814cf74056 220 Gene3D G3DSA:3.20.20.70 1 214 2.5E-65 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS14385 bfabdd738cc4915d44ddb8814cf74056 220 Pfam PF00923 Transaldolase 3 206 7.2E-48 T 10-03-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS14385 bfabdd738cc4915d44ddb8814cf74056 220 Hamap MF_00496 Fructose-6-phosphate aldolase [fsa]. 1 220 52.49 T 10-03-2017 IPR023001 Fructose-6-phosphate aldolase GO:0016832 RG49_RS14385 bfabdd738cc4915d44ddb8814cf74056 220 ProSitePatterns PS00958 Transaldolase active site. 82 99 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS14385 bfabdd738cc4915d44ddb8814cf74056 220 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 10-03-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 RG49_RS14385 bfabdd738cc4915d44ddb8814cf74056 220 SUPERFAMILY SSF51569 1 216 2.2E-65 T 10-03-2017 RG49_RS14385 bfabdd738cc4915d44ddb8814cf74056 220 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 215 4.1E-107 T 10-03-2017 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS09810 d89af1506189513ef8125cbca8e031e5 97 Pfam PF06291 Bor protein 1 97 1.3E-60 T 10-03-2017 IPR010438 Bor GO:0009279 RG49_RS09810 d89af1506189513ef8125cbca8e031e5 97 ProDom PD020173 BOR LIPOPROTEIN PLASMID ISS HOMOLOG MEMBRANE FROM PRECURSOR PALMITATE DLP12 1 96 3.0E-50 T 10-03-2017 IPR010438 Bor GO:0009279 RG49_RS13255 20fde03ece91131961c278aac4e36553 191 SUPERFAMILY SSF48498 86 179 1.08E-5 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS13255 20fde03ece91131961c278aac4e36553 191 Gene3D G3DSA:1.10.357.10 2 179 6.0E-18 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS13255 20fde03ece91131961c278aac4e36553 191 SUPERFAMILY SSF46689 3 69 9.75E-8 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 254 7.7E-63 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 253 1.6E-100 T 10-03-2017 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 10-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 SUPERFAMILY SSF53850 26 257 1.49E-65 T 10-03-2017 RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 SMART SM00062 27 256 3.0E-78 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 Gene3D G3DSA:3.40.190.10 116 213 6.2E-32 T 10-03-2017 RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 Gene3D G3DSA:3.40.190.10 26 113 2.0E-44 T 10-03-2017 RG49_RS23530 65a926bfd2167943d8099013a707a4ac 260 Gene3D G3DSA:3.40.190.10 215 257 2.0E-44 T 10-03-2017 RG49_RS11100 10751b546949b42c50b92818301ccad2 234 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 234 58.857 T 10-03-2017 IPR005224 Sugar fermentation stimulation protein RG49_RS11100 10751b546949b42c50b92818301ccad2 234 Pfam PF03749 Sugar fermentation stimulation protein 13 225 1.4E-77 T 10-03-2017 IPR005224 Sugar fermentation stimulation protein RG49_RS11100 10751b546949b42c50b92818301ccad2 234 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 234 1.0E-105 T 10-03-2017 IPR005224 Sugar fermentation stimulation protein RG49_RS07335 86c43f5657f6e673ece51a453a9db8d0 263 Pfam PF16331 TolA binding protein trimerisation 37 111 8.3E-25 T 10-03-2017 IPR032519 YbgF, trimerisation domain GO:0070206 RG49_RS07335 86c43f5657f6e673ece51a453a9db8d0 263 Gene3D G3DSA:1.25.40.10 145 250 2.0E-12 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS07335 86c43f5657f6e673ece51a453a9db8d0 263 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 144 260 3.7E-40 T 10-03-2017 IPR014162 Tol-Pal system, YbgF RG49_RS07335 86c43f5657f6e673ece51a453a9db8d0 263 Pfam PF13432 Tetratricopeptide repeat 159 214 8.7E-6 T 10-03-2017 RG49_RS07335 86c43f5657f6e673ece51a453a9db8d0 263 SUPERFAMILY SSF48452 139 254 1.84E-12 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS07335 86c43f5657f6e673ece51a453a9db8d0 263 Pfam PF13174 Tetratricopeptide repeat 218 250 4.8E-7 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS14545 584800b59681e462425a4237fd481a99 329 Pfam PF13531 Bacterial extracellular solute-binding protein 32 280 2.0E-46 T 10-03-2017 RG49_RS14545 584800b59681e462425a4237fd481a99 329 SUPERFAMILY SSF53850 21 326 1.09E-93 T 10-03-2017 RG49_RS14545 584800b59681e462425a4237fd481a99 329 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 12 326 2.2E-192 T 10-03-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 RG49_RS14545 584800b59681e462425a4237fd481a99 329 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 145 153 - T 10-03-2017 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 RG49_RS14545 584800b59681e462425a4237fd481a99 329 Gene3D G3DSA:3.40.190.10 170 295 1.2E-33 T 10-03-2017 RG49_RS14545 584800b59681e462425a4237fd481a99 329 Gene3D G3DSA:3.40.190.10 21 164 2.5E-51 T 10-03-2017 RG49_RS14545 584800b59681e462425a4237fd481a99 329 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 48 60 - T 10-03-2017 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 RG49_RS10135 575eecdbb22069ea6376a282da3f5086 105 SUPERFAMILY SSF143737 4 104 7.19E-52 T 10-03-2017 RG49_RS10135 575eecdbb22069ea6376a282da3f5086 105 Pfam PF06154 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A 5 104 2.8E-52 T 10-03-2017 IPR009320 YagB/YeeU/YfjZ RG49_RS10135 575eecdbb22069ea6376a282da3f5086 105 Gene3D G3DSA:3.30.450.20 13 104 8.3E-51 T 10-03-2017 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 Gene3D G3DSA:1.10.285.10 7 67 8.2E-28 T 10-03-2017 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 Gene3D G3DSA:1.10.285.10 373 446 2.0E-26 T 10-03-2017 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 184 7.7E-49 T 10-03-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 PIRSF PIRSF000185 22 447 1.8E-114 T 10-03-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 SUPERFAMILY SSF53223 6 196 6.72E-74 T 10-03-2017 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 445 1.5E-87 T 10-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 SMART SM00839 204 445 2.0E-93 T 10-03-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 10-03-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 Gene3D G3DSA:3.40.50.720 209 372 1.6E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 Gene3D G3DSA:3.40.192.10 68 188 1.0E-60 T 10-03-2017 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 SUPERFAMILY SSF51735 202 446 4.96E-77 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 2.5E-33 T 10-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 2.5E-33 T 10-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 2.5E-33 T 10-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 RG49_RS01185 9ec8e26fcf5c160f533bf9a69dec0212 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 2.5E-33 T 10-03-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 RG49_RS11615 10af8e029d2976e91ee59bcb09e86b15 125 SUPERFAMILY SSF110069 5 125 2.09E-48 T 10-03-2017 IPR007474 ApaG domain RG49_RS11615 10af8e029d2976e91ee59bcb09e86b15 125 Hamap MF_00791 Protein ApaG [apaG]. 1 125 33.655 T 10-03-2017 IPR023065 Uncharacterised protein family ApaG RG49_RS11615 10af8e029d2976e91ee59bcb09e86b15 125 Pfam PF04379 Protein of unknown function (DUF525) 18 102 1.9E-33 T 10-03-2017 IPR007474 ApaG domain RG49_RS11615 10af8e029d2976e91ee59bcb09e86b15 125 Gene3D G3DSA:2.60.40.1470 6 125 4.6E-46 T 10-03-2017 IPR007474 ApaG domain RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 PIRSF PIRSF000521 30 423 1.0E-30 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 Gene3D G3DSA:3.90.1150.10 1 61 9.4E-65 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 Gene3D G3DSA:3.90.1150.10 332 423 9.4E-65 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 242 279 - T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 Pfam PF00202 Aminotransferase class-III 27 420 2.0E-133 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 Gene3D G3DSA:3.40.640.10 62 328 8.6E-94 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 424 52.314 T 10-03-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 SUPERFAMILY SSF53383 1 422 5.04E-139 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS07160 62dae4061648b2cb697bc3b505e06aa0 429 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 13 421 5.4E-185 T 10-03-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 RG49_RS17145 a86d0c1ed049aa788670d814e60237c6 378 Pfam PF01609 Transposase DDE domain 102 343 7.1E-30 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS17145 a86d0c1ed049aa788670d814e60237c6 378 Pfam PF13808 DDE_Tnp_1-associated 7 94 1.0E-32 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS11140 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS07865 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS19980 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS20785 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS08835 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS03750 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS09845 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS16560 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS19930 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS16025 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS09790 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS05535 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS03515 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS09585 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS05020 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS12515 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS08410 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS15610 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS03560 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS15980 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS09695 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS16625 bd1aaa2742c8ed5c79d807d31c630327 167 Pfam PF03400 IS1 transposase 37 167 1.5E-78 T 10-03-2017 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 RG49_RS04935 307e4dafc622b419abd71db1a90ceebe 153 Gene3D G3DSA:3.90.79.10 2 143 9.1E-34 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS04935 307e4dafc622b419abd71db1a90ceebe 153 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS04935 307e4dafc622b419abd71db1a90ceebe 153 PRINTS PR00502 NUDIX hydrolase family signature 31 45 8.1E-6 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS04935 307e4dafc622b419abd71db1a90ceebe 153 PRINTS PR00502 NUDIX hydrolase family signature 45 60 8.1E-6 T 10-03-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 RG49_RS04935 307e4dafc622b419abd71db1a90ceebe 153 SUPERFAMILY SSF55811 5 152 1.14E-30 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS04935 307e4dafc622b419abd71db1a90ceebe 153 Pfam PF00293 NUDIX domain 4 114 8.0E-19 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS08180 3dfaab2794194c5ef8e7c06bb2842a59 416 Hamap MF_01436 Enterobactin exporter EntS [entS]. 1 414 43.506 T 10-03-2017 IPR023722 Enterobactin exporter, EntS GO:0005886|GO:0042930|GO:0042931 RG49_RS08180 3dfaab2794194c5ef8e7c06bb2842a59 416 Gene3D G3DSA:1.20.1250.20 239 402 3.1E-12 T 10-03-2017 RG49_RS08180 3dfaab2794194c5ef8e7c06bb2842a59 416 Gene3D G3DSA:1.20.1250.20 16 206 4.1E-22 T 10-03-2017 RG49_RS08180 3dfaab2794194c5ef8e7c06bb2842a59 416 Pfam PF05977 Transmembrane secretion effector 16 405 2.3E-20 T 10-03-2017 IPR010290 Transmembrane secretion effector RG49_RS08180 3dfaab2794194c5ef8e7c06bb2842a59 416 SUPERFAMILY SSF103473 16 403 2.62E-41 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 SUPERFAMILY SSF51735 1 56 2.46E-8 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 32 39 - T 10-03-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 Gene3D G3DSA:3.30.360.10 43 133 6.5E-46 T 10-03-2017 RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1 34 2.7E-6 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 SUPERFAMILY SSF55347 33 133 3.79E-44 T 10-03-2017 RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 Gene3D G3DSA:3.40.50.720 1 42 4.4E-20 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 129 9.5E-20 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 28 46 9.5E-20 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 55 71 9.5E-20 T 10-03-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03340 f4ae3a5a070e5f928f0c4e6bf82cbacc 134 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 39 133 3.1E-42 T 10-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS00095 792424e3abc7ac6c4a8b4325a7b962f6 231 Pfam PF01966 HD domain 29 131 3.7E-15 T 10-03-2017 IPR006674 HD domain RG49_RS00095 792424e3abc7ac6c4a8b4325a7b962f6 231 Gene3D G3DSA:1.10.3210.10 184 214 5.2E-45 T 10-03-2017 IPR006674 HD domain RG49_RS00095 792424e3abc7ac6c4a8b4325a7b962f6 231 Gene3D G3DSA:1.10.3210.10 2 145 5.2E-45 T 10-03-2017 IPR006674 HD domain RG49_RS00095 792424e3abc7ac6c4a8b4325a7b962f6 231 SUPERFAMILY SSF109604 1 214 4.4E-62 T 10-03-2017 RG49_RS00095 792424e3abc7ac6c4a8b4325a7b962f6 231 SMART SM00471 22 141 3.0E-9 T 10-03-2017 IPR003607 HD/PDEase domain RG49_RS18400 c638711cbdded3bee890efdd9a8123be 481 Pfam PF01523 Putative modulator of DNA gyrase 36 332 2.0E-63 T 10-03-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 RG49_RS18400 c638711cbdded3bee890efdd9a8123be 481 PIRSF PIRSF004919 14 481 1.9E-158 T 10-03-2017 IPR025502 TldD RG49_RS18400 c638711cbdded3bee890efdd9a8123be 481 SUPERFAMILY SSF111283 22 480 1.57E-132 T 10-03-2017 RG49_RS23540 8e2f00c641ea643bdbd969a367b8215b 228 Gene3D G3DSA:1.10.3720.10 8 219 6.6E-39 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23540 8e2f00c641ea643bdbd969a367b8215b 228 SUPERFAMILY SSF161098 7 205 1.2E-37 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23540 8e2f00c641ea643bdbd969a367b8215b 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 219 3.5E-23 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23540 8e2f00c641ea643bdbd969a367b8215b 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 114 7.9E-19 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 188 1.1E-60 T 10-03-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 PIRSF PIRSF500136 1 420 5.2E-148 T 10-03-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 SUPERFAMILY SSF52413 311 419 2.88E-24 T 10-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 SMART SM00984 324 420 3.9E-21 T 10-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 Hamap MF_02029 UDP-N-acetyl-D-mannosamine dehydrogenase [wecC]. 1 420 74.075 T 10-03-2017 IPR032891 UDP-N-acetyl-D-mannosamine dehydrogenase WecC GO:0009246|GO:0089714 KEGG: 00520+1.1.1.336|MetaCyc: PWY-7335 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 Gene3D G3DSA:3.40.50.720 237 419 1.1E-45 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 SUPERFAMILY SSF48179 206 298 2.72E-28 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 419 5.2E-18 T 10-03-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 Gene3D G3DSA:3.40.50.720 3 227 3.1E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 416 2.5E-119 T 10-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 293 1.2E-26 T 10-03-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 PIRSF PIRSF000124 4 419 1.6E-77 T 10-03-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 RG49_RS15275 b537b28dee348e1b4fa837926fcf6501 420 SUPERFAMILY SSF51735 5 198 5.92E-46 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21040 0530c5e9c40db1a656c982bb16deb794 438 SUPERFAMILY SSF103473 20 431 6.93E-43 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS21040 0530c5e9c40db1a656c982bb16deb794 438 Pfam PF07690 Major Facilitator Superfamily 33 387 5.5E-20 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS21040 0530c5e9c40db1a656c982bb16deb794 438 Gene3D G3DSA:1.20.1250.20 28 233 1.8E-19 T 10-03-2017 RG49_RS21040 0530c5e9c40db1a656c982bb16deb794 438 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 24 432 1.1E-204 T 10-03-2017 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 RG49_RS21040 0530c5e9c40db1a656c982bb16deb794 438 Gene3D G3DSA:1.20.1250.20 257 431 9.3E-6 T 10-03-2017 RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 3 142 2.1E-18 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 PRINTS PR00885 Bacterial general secretion pathway protein H signature 122 137 1.6E-20 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 PRINTS PR00885 Bacterial general secretion pathway protein H signature 17 31 1.6E-20 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 PRINTS PR00885 Bacterial general secretion pathway protein H signature 2 16 1.6E-20 T 10-03-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 4.8E-8 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 1 26 1.1E-7 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 Gene3D G3DSA:3.55.40.10 40 160 4.2E-14 T 10-03-2017 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 Pfam PF12019 Type II transport protein GspH 44 143 1.4E-9 T 10-03-2017 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 RG49_RS17960 46f18d7a9afb8947503742ba8b2d9f24 169 SUPERFAMILY SSF54523 7 103 6.2E-13 T 10-03-2017 RG49_RS25000 53f2bb62952d22b004b94e74f3d3a6d1 361 Gene3D G3DSA:3.90.25.10 200 354 5.6E-57 T 10-03-2017 RG49_RS25000 53f2bb62952d22b004b94e74f3d3a6d1 361 SUPERFAMILY SSF51735 2 356 2.75E-92 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25000 53f2bb62952d22b004b94e74f3d3a6d1 361 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 330 1.2E-98 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25000 53f2bb62952d22b004b94e74f3d3a6d1 361 Gene3D G3DSA:3.40.50.720 2 199 2.6E-65 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25000 53f2bb62952d22b004b94e74f3d3a6d1 361 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 343 9.3E-155 T 10-03-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 RG49_RS19060 2e858b55282a3f36664feb3db177da30 486 Gene3D G3DSA:1.10.443.10 301 469 1.3E-24 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS19060 2e858b55282a3f36664feb3db177da30 486 Pfam PF11646 Protein of unknown function DUF3258 183 263 1.6E-9 T 10-03-2017 IPR021672 Protein of unknown function DUF3258 RG49_RS19060 2e858b55282a3f36664feb3db177da30 486 Pfam PF00589 Phage integrase family 303 469 4.2E-14 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS19060 2e858b55282a3f36664feb3db177da30 486 SUPERFAMILY SSF56349 169 225 7.36E-36 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS19060 2e858b55282a3f36664feb3db177da30 486 SUPERFAMILY SSF56349 252 469 7.36E-36 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS22520 e4e55dc6a13010f0dbb6e3696e88e31e 71 Pfam PF07191 zinc-ribbons 4 68 5.3E-29 T 10-03-2017 IPR010807 Protein of unknown function DUF1407 RG49_RS22520 e4e55dc6a13010f0dbb6e3696e88e31e 71 ProDom PD060428 YFGJ CYTOPLASMIC VP0614 ECS3372 VC0765 YPO2873 Y1359 STY2763A VV0773 1 71 9.0E-36 T 10-03-2017 IPR010807 Protein of unknown function DUF1407 RG49_RS22520 e4e55dc6a13010f0dbb6e3696e88e31e 71 SUPERFAMILY SSF161187 1 69 6.02E-29 T 10-03-2017 IPR029037 YfgJ-like RG49_RS22520 e4e55dc6a13010f0dbb6e3696e88e31e 71 Gene3D G3DSA:2.10.290.10 1 70 4.1E-35 T 10-03-2017 IPR029037 YfgJ-like RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 Gene3D G3DSA:3.40.50.620 4 174 5.8E-44 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 10-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 SUPERFAMILY SSF69864 190 444 7.59E-81 T 10-03-2017 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 SUPERFAMILY SSF52402 3 186 6.05E-35 T 10-03-2017 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 Gene3D G3DSA:3.90.1260.10 175 372 1.8E-63 T 10-03-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 Gene3D G3DSA:1.10.287.400 377 440 3.4E-35 T 10-03-2017 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 3.3E-170 T 10-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 443 78.07 T 10-03-2017 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 10-03-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS18785 a14eee6a28425349b6d6e22e2d36112d 447 Pfam PF00764 Arginosuccinate synthase 16 410 8.8E-57 T 10-03-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 Gene3D G3DSA:3.30.420.40 254 468 2.8E-34 T 10-03-2017 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 Gene3D G3DSA:3.30.420.40 1 250 1.4E-55 T 10-03-2017 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 Hamap MF_00986 L-fuculokinase [fucK]. 3 464 62.774 T 10-03-2017 IPR013450 L-fuculokinase GO:0005975|GO:0008737 KEGG: 00051+2.7.1.51 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 438 1.2E-21 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 PIRSF PIRSF000538 3 472 1.4E-84 T 10-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 351 371 - T 10-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 SUPERFAMILY SSF53067 5 252 4.32E-62 T 10-03-2017 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 TIGRFAM TIGR02628 fuculo_kin_coli: L-fuculokinase 4 463 1.4E-255 T 10-03-2017 IPR013450 L-fuculokinase GO:0005975|GO:0008737 KEGG: 00051+2.7.1.51 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 10-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 249 9.4E-89 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS21030 c90262ca07247f04717e05ada7f0b306 472 SUPERFAMILY SSF53067 254 467 4.04E-41 T 10-03-2017 RG49_RS01900 0d36786da5a0387f0e1180b36b15a061 352 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 349 4.0E-151 T 10-03-2017 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 RG49_RS01900 0d36786da5a0387f0e1180b36b15a061 352 Pfam PF03116 NQR2, RnfD, RnfE family 6 348 9.2E-109 T 10-03-2017 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 RG49_RS01900 0d36786da5a0387f0e1180b36b15a061 352 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 3 350 28.952 T 10-03-2017 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 RG49_RS09380 da10eaa6e06640558dea3773f0f7dd3c 269 Hamap MF_01655 2-keto-4-pentenoate hydratase [mhpD]. 1 260 56.925 T 10-03-2017 IPR023793 2-keto-4-pentenoate hydratase GO:0008684|GO:0019439|GO:0030145 KEGG: 00360+4.2.1.80|KEGG: 00362+4.2.1.80|KEGG: 00621+4.2.1.80|KEGG: 00622+4.2.1.80|MetaCyc: PWY-5162 RG49_RS09380 da10eaa6e06640558dea3773f0f7dd3c 269 SUPERFAMILY SSF56529 1 259 8.24E-81 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS09380 da10eaa6e06640558dea3773f0f7dd3c 269 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 93 259 1.0E-21 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS09380 da10eaa6e06640558dea3773f0f7dd3c 269 Gene3D G3DSA:3.90.850.10 1 259 1.3E-93 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS02635 b77f1138e788d95be99dd42a9de71400 252 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 2 251 48.815 T 10-03-2017 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 RG49_RS02635 b77f1138e788d95be99dd42a9de71400 252 SUPERFAMILY SSF53335 21 239 1.22E-35 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS02635 b77f1138e788d95be99dd42a9de71400 252 Pfam PF13489 Methyltransferase domain 14 176 1.7E-16 T 10-03-2017 RG49_RS02635 b77f1138e788d95be99dd42a9de71400 252 Gene3D G3DSA:3.40.50.150 22 131 5.1E-21 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS02635 b77f1138e788d95be99dd42a9de71400 252 Gene3D G3DSA:1.10.150.290 132 230 1.2E-30 T 10-03-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 Gene3D G3DSA:3.40.50.2300 2 136 1.8E-36 T 10-03-2017 RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 SUPERFAMILY SSF52172 3 132 1.85E-37 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 SUPERFAMILY SSF46894 126 226 1.25E-24 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 Gene3D G3DSA:1.10.10.10 137 227 1.0E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.5E-23 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 Pfam PF00072 Response regulator receiver domain 6 115 2.2E-26 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 SMART SM00862 150 226 4.5E-23 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS11915 1fc4a92c1e1892d96c1d247a9d864b97 229 SMART SM00448 4 115 9.7E-37 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 163 219 5.2E-9 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 19 141 4.6E-40 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 SUPERFAMILY SSF49584 136 221 1.31E-16 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 SUPERFAMILY SSF49354 15 141 1.86E-39 T 10-03-2017 IPR008962 PapD-like RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 96 113 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 Gene3D G3DSA:2.60.40.1070 147 220 7.6E-16 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 Gene3D G3DSA:2.60.40.360 19 141 1.2E-41 T 10-03-2017 IPR008962 PapD-like RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 PRINTS PR00969 Pili chaperone signature 20 29 5.3E-27 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 PRINTS PR00969 Pili chaperone signature 69 90 5.3E-27 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 PRINTS PR00969 Pili chaperone signature 158 173 5.3E-27 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 PRINTS PR00969 Pili chaperone signature 97 114 5.3E-27 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS24635 22a2f4defc32a103db333832edecaf63 224 PRINTS PR00969 Pili chaperone signature 123 138 5.3E-27 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 Pfam PF00171 Aldehyde dehydrogenase family 8 282 2.9E-16 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 9 406 4.0E-203 T 10-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 PIRSF PIRSF000151 1 417 1.8E-179 T 10-03-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 323 344 - T 10-03-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 Gene3D G3DSA:3.40.605.10 375 416 3.2E-104 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 Gene3D G3DSA:3.40.605.10 2 220 3.2E-104 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 Gene3D G3DSA:3.40.309.10 223 374 4.9E-42 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 SUPERFAMILY SSF53720 3 416 1.18E-116 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS10460 e465935ff61a153e054214ab25c51637 417 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 1 416 41.816 T 10-03-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 Pfam PF00375 Sodium:dicarboxylate symporter family 29 443 5.8E-104 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 PRINTS PR00173 Glutamate-aspartate symporter signature 75 95 2.1E-27 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 PRINTS PR00173 Glutamate-aspartate symporter signature 27 47 2.1E-27 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 2.1E-27 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 2.1E-27 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 PRINTS PR00173 Glutamate-aspartate symporter signature 105 130 2.1E-27 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 2.1E-27 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 SUPERFAMILY SSF118215 29 443 3.53E-98 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS01360 d591201bb48eb0d191bfafac27ba17cd 463 Gene3D G3DSA:1.10.3860.10 23 449 7.6E-103 T 10-03-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 RG49_RS07005 f5cb5c424de48462170a320fa4d4d2f4 225 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 225 45.719 T 10-03-2017 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 RG49_RS07005 f5cb5c424de48462170a320fa4d4d2f4 225 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 175 7.3E-15 T 10-03-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 RG49_RS07005 f5cb5c424de48462170a320fa4d4d2f4 225 SMART SM00702 1 176 4.2E-34 T 10-03-2017 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 RG49_RS07005 f5cb5c424de48462170a320fa4d4d2f4 225 SUPERFAMILY SSF51197 4 177 4.94E-9 T 10-03-2017 RG49_RS16065 8adfaf27988d2f2edff63ad6250dc1c8 773 Pfam PF12696 TraM recognition site of TraD and TraG 435 528 1.3E-4 T 10-03-2017 IPR032689 TraD/TraG, TraM recognition site RG49_RS16065 8adfaf27988d2f2edff63ad6250dc1c8 773 Gene3D G3DSA:3.40.50.300 108 204 2.9E-15 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16065 8adfaf27988d2f2edff63ad6250dc1c8 773 Gene3D G3DSA:3.40.50.300 365 569 2.9E-15 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16065 8adfaf27988d2f2edff63ad6250dc1c8 773 SUPERFAMILY SSF52540 106 568 5.84E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 Pfam PF00107 Zinc-binding dehydrogenase 197 268 2.6E-9 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 SUPERFAMILY SSF50129 1 200 8.07E-59 T 10-03-2017 IPR011032 GroES-like RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 Gene3D G3DSA:3.90.180.10 1 188 1.6E-55 T 10-03-2017 IPR011032 GroES-like RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 1.4E-11 T 10-03-2017 IPR027399 Alcohol dehydrogenase GroES-associated RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 Gene3D G3DSA:3.40.50.720 189 330 1.1E-34 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 151 3.7E-30 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 SUPERFAMILY SSF51735 164 349 2.63E-58 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08080 db0e2b2b3872ec3003311d116dbe7655 412 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 Gene3D G3DSA:1.10.10.60 222 255 1.8E-7 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 Gene3D G3DSA:2.60.120.10 32 93 1.0E-8 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 SUPERFAMILY SSF51182 23 157 5.93E-13 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 SUPERFAMILY SSF46689 213 259 1.34E-6 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 211 252 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 Pfam PF12833 Helix-turn-helix domain 180 257 9.6E-18 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 SMART SM00342 173 256 2.1E-19 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 Pfam PF02311 AraC-like ligand binding domain 22 96 5.1E-5 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS01035 e173fee78fd5016f2790d2d6e479eb65 273 Gene3D G3DSA:1.10.10.60 155 212 2.0E-5 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 SUPERFAMILY SSF46894 118 218 7.37E-27 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 Pfam PF00072 Response regulator receiver domain 3 113 1.3E-25 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 SMART SM00862 145 216 9.1E-22 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.7E-20 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 Gene3D G3DSA:1.10.10.10 124 219 8.9E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 SUPERFAMILY SSF52172 1 132 8.68E-36 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 Gene3D G3DSA:3.40.50.2300 1 123 2.6E-35 T 10-03-2017 RG49_RS13390 7abf516279ea0ff27a6552c9ad978d94 222 SMART SM00448 1 112 9.9E-36 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS04800 48e12cecac761e9a37f181be663a4bfe 88 Gene3D G3DSA:3.30.1070.10 31 85 6.0E-26 T 10-03-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 RG49_RS04800 48e12cecac761e9a37f181be663a4bfe 88 SUPERFAMILY SSF55229 32 85 1.22E-18 T 10-03-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 RG49_RS04800 48e12cecac761e9a37f181be663a4bfe 88 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 19.958 T 10-03-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 RG49_RS04800 48e12cecac761e9a37f181be663a4bfe 88 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 4.0E-25 T 10-03-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 RG49_RS04800 48e12cecac761e9a37f181be663a4bfe 88 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 3.4E-37 T 10-03-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 RG49_RS10855 bf929418f511765a3781435504d335f2 140 Gene3D G3DSA:3.30.160.200 3 107 7.4E-35 T 10-03-2017 RG49_RS10855 bf929418f511765a3781435504d335f2 140 Pfam PF00472 RF-1 domain 6 132 2.9E-28 T 10-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 RG49_RS10855 bf929418f511765a3781435504d335f2 140 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 10-03-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 RG49_RS10855 bf929418f511765a3781435504d335f2 140 SUPERFAMILY SSF75620 7 110 1.73E-15 T 10-03-2017 RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 5.6E-20 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 2.7E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 2.7E-9 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 Gene3D G3DSA:1.10.10.10 8 76 3.2E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 Hamap MF_00696 Fatty acid metabolism regulator protein [fadR]. 1 239 162.307 T 10-03-2017 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 SUPERFAMILY SSF46785 11 88 2.48E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 SUPERFAMILY SSF48008 79 230 5.75E-65 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 Pfam PF07840 FadR C-terminal domain 72 234 5.1E-73 T 10-03-2017 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 Gene3D G3DSA:1.20.120.530 80 236 8.9E-69 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 SMART SM00345 12 71 5.9E-23 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS04725 48835af5c3e5c8f2b7aba321dfbe6aff 239 TIGRFAM TIGR02812 fadR_gamma: fatty acid metabolism transcriptional regulator FadR 2 235 1.1E-123 T 10-03-2017 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 Hamap MF_01516 Malate dehydrogenase [mdh]. 1 311 61.568 T 10-03-2017 IPR023958 Malate dehydrogenase, type 1, bacterial GO:0006099|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 SUPERFAMILY SSF51735 1 145 3.51E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 Gene3D G3DSA:3.40.50.720 1 146 1.3E-57 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 TIGRFAM TIGR01772 MDH_euk_gproteo: malate dehydrogenase, NAD-dependent 2 311 1.2E-140 T 10-03-2017 IPR010097 Malate dehydrogenase, type 1 GO:0006108|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263|Reactome: R-HSA-71403 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 145 6.6E-46 T 10-03-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 SUPERFAMILY SSF56327 146 311 2.16E-42 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 146 158 - T 10-03-2017 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 Gene3D G3DSA:3.90.110.10 147 311 6.9E-64 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 PIRSF PIRSF000102 1 310 6.7E-60 T 10-03-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 RG49_RS18440 e900d4236746abfdd6436dab2615ca4b 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 310 1.9E-52 T 10-03-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 RG49_RS12215 40375d0e2ef33314d920bcbabc0875cc 262 Gene3D G3DSA:3.20.20.60 1 250 1.3E-85 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS12215 40375d0e2ef33314d920bcbabc0875cc 262 SUPERFAMILY SSF51621 2 250 9.74E-86 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS12215 40375d0e2ef33314d920bcbabc0875cc 262 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 3 250 4.7E-131 T 10-03-2017 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 RG49_RS12215 40375d0e2ef33314d920bcbabc0875cc 262 Hamap MF_01292 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase [hpcH]. 1 262 64.264 T 10-03-2017 IPR023701 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, Enterobacteriales GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 RG49_RS12215 40375d0e2ef33314d920bcbabc0875cc 262 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 241 1.4E-66 T 10-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 RG49_RS17875 ef1fc8010739057d521c2c08f6fa32f9 240 Pfam PF08348 YheO-like PAS domain 29 137 2.2E-35 T 10-03-2017 IPR013559 YheO-like RG49_RS17875 ef1fc8010739057d521c2c08f6fa32f9 240 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 27 153 6.0E-71 T 10-03-2017 IPR013559 YheO-like RG49_RS17875 ef1fc8010739057d521c2c08f6fa32f9 240 Pfam PF13309 HTH domain 171 228 2.9E-19 T 10-03-2017 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 SUPERFAMILY SSF81340 15 453 1.96E-111 T 10-03-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 PRINTS PR00762 Chloride channel signature 387 403 3.1E-28 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 PRINTS PR00762 Chloride channel signature 183 202 3.1E-28 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 PRINTS PR00762 Chloride channel signature 102 119 3.1E-28 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 PRINTS PR00762 Chloride channel signature 405 424 3.1E-28 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 PRINTS PR00762 Chloride channel signature 352 372 3.1E-28 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 Hamap MF_01128 H(+)/Cl(-) exchange transporter ClcA [clcA]. 3 469 47.995 T 10-03-2017 IPR023861 Chloride channel, ClcA GO:0005887|GO:0006821|GO:0015108 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 Pfam PF00654 Voltage gated chloride channel 89 437 3.4E-89 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS11050 cc50097b245098fa32ff05d39746678f 473 Gene3D G3DSA:1.10.3080.10 26 452 4.5E-101 T 10-03-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 RG49_RS06005 e138709ee53677e5c338f9968cb71ca6 187 SUPERFAMILY SSF49401 42 187 2.34E-33 T 10-03-2017 IPR008966 Adhesion domain RG49_RS06005 e138709ee53677e5c338f9968cb71ca6 187 Gene3D G3DSA:2.60.40.1090 41 186 5.1E-38 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS06005 e138709ee53677e5c338f9968cb71ca6 187 Pfam PF00419 Fimbrial protein 44 186 2.6E-15 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12905 eb3b97ed13530ca6568258f44c46e3b4 131 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.683 T 10-03-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 RG49_RS12905 eb3b97ed13530ca6568258f44c46e3b4 131 SUPERFAMILY SSF54995 1 103 1.02E-37 T 10-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12905 eb3b97ed13530ca6568258f44c46e3b4 131 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 10-03-2017 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 RG49_RS12905 eb3b97ed13530ca6568258f44c46e3b4 131 Pfam PF01250 Ribosomal protein S6 3 91 3.2E-28 T 10-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12905 eb3b97ed13530ca6568258f44c46e3b4 131 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 3.3E-39 T 10-03-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12905 eb3b97ed13530ca6568258f44c46e3b4 131 Gene3D G3DSA:3.30.70.60 1 103 3.8E-42 T 10-03-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 RG49_RS19855 c29d53bc3f1b9354a28259067f38258a 186 TIGRFAM TIGR01626 ytfJ_HI0045: conserved hypothetical protein YtfJ-family, TIGR01626 1 184 1.2E-62 T 10-03-2017 IPR006513 Conserved hypothetical protein CHP01626, YtfJ RG49_RS19855 c29d53bc3f1b9354a28259067f38258a 186 Pfam PF09695 Bacterial protein of unknown function (YtfJ_HI0045) 25 182 4.9E-58 T 10-03-2017 IPR006513 Conserved hypothetical protein CHP01626, YtfJ RG49_RS21780 6da23bd7f490292f8b291d835394509d 426 Gene3D G3DSA:3.40.640.10 59 303 5.1E-82 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS21780 6da23bd7f490292f8b291d835394509d 426 Gene3D G3DSA:3.90.1150.10 304 423 1.9E-43 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS21780 6da23bd7f490292f8b291d835394509d 426 SUPERFAMILY SSF53383 20 423 9.41E-136 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS21780 6da23bd7f490292f8b291d835394509d 426 Pfam PF00202 Aminotransferase class-III 17 420 3.7E-144 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS21780 6da23bd7f490292f8b291d835394509d 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS21780 6da23bd7f490292f8b291d835394509d 426 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 420 5.5E-163 T 10-03-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 RG49_RS22720 9760dc5822fb36642d47ed35abc51d22 526 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 321 333 4.9E-8 T 10-03-2017 RG49_RS22720 9760dc5822fb36642d47ed35abc51d22 526 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 228 249 4.9E-8 T 10-03-2017 RG49_RS22720 9760dc5822fb36642d47ed35abc51d22 526 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 4.9E-8 T 10-03-2017 RG49_RS22720 9760dc5822fb36642d47ed35abc51d22 526 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 102 6.5E-6 T 10-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22720 9760dc5822fb36642d47ed35abc51d22 526 Pfam PF00361 Proton-conducting membrane transporter 132 425 3.8E-56 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 Gene3D G3DSA:3.40.630.30 37 116 4.5E-9 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 147 204 3.8E-11 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 SUPERFAMILY SSF52374 145 335 3.31E-25 T 10-03-2017 RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 Pfam PF08218 Citrate lyase ligase C-terminal domain 147 333 2.0E-84 T 10-03-2017 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 PIRSF PIRSF005751 1 351 2.8E-144 T 10-03-2017 IPR005216 Citrate lyase ligase GO:0008771 RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 SMART SM00764 147 333 7.7E-135 T 10-03-2017 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 Gene3D G3DSA:3.40.50.620 128 335 4.7E-39 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 TIGRFAM TIGR00124 cit_ly_ligase: [citrate (pro-3S)-lyase] ligase 7 342 2.5E-179 T 10-03-2017 IPR005216 Citrate lyase ligase GO:0008771 RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 SUPERFAMILY SSF55729 34 116 6.45E-9 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS08025 9ae99b578fc0484dd23857f4ca6d1ee4 352 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 113 338 2.0E-132 T 10-03-2017 RG49_RS04295 ba6041c09b74a8a96f61c7c64f2c02b8 166 SUPERFAMILY SSF47240 3 159 1.57E-50 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS04295 ba6041c09b74a8a96f61c7c64f2c02b8 166 Gene3D G3DSA:1.20.1260.10 1 165 1.6E-66 T 10-03-2017 IPR012347 Ferritin-related RG49_RS04295 ba6041c09b74a8a96f61c7c64f2c02b8 166 Pfam PF05974 Domain of unknown function (DUF892) 5 163 1.2E-54 T 10-03-2017 IPR010287 Domain of unknown function DUF892 RG49_RS20465 dcb56ab24fbe0d67496b35a5bb0bdf9a 482 TIGRFAM TIGR03173 pbuX: xanthine permease 33 443 1.3E-153 T 10-03-2017 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 RG49_RS20465 dcb56ab24fbe0d67496b35a5bb0bdf9a 482 Pfam PF00860 Permease family 29 408 6.1E-122 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS20465 dcb56ab24fbe0d67496b35a5bb0bdf9a 482 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 357 377 - T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS20465 dcb56ab24fbe0d67496b35a5bb0bdf9a 482 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 29 440 1.3E-136 T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS10810 800f3cfcd8325fe06e83e6bddfd24778 190 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 6 181 3.3E-101 T 10-03-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 RG49_RS10810 800f3cfcd8325fe06e83e6bddfd24778 190 Gene3D G3DSA:3.40.50.1000 3 183 4.3E-63 T 10-03-2017 IPR023214 HAD-like domain RG49_RS10810 800f3cfcd8325fe06e83e6bddfd24778 190 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 7 155 1.1E-38 T 10-03-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 RG49_RS10810 800f3cfcd8325fe06e83e6bddfd24778 190 Pfam PF13242 HAD-hyrolase-like 109 179 2.7E-12 T 10-03-2017 RG49_RS10810 800f3cfcd8325fe06e83e6bddfd24778 190 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 154 2.5E-38 T 10-03-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 RG49_RS10810 800f3cfcd8325fe06e83e6bddfd24778 190 PIRSF PIRSF004682 1 189 3.0E-67 T 10-03-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 RG49_RS10810 800f3cfcd8325fe06e83e6bddfd24778 190 SUPERFAMILY SSF56784 5 184 3.03E-53 T 10-03-2017 IPR023214 HAD-like domain RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 SUPERFAMILY SSF88723 34 189 3.48E-37 T 10-03-2017 IPR029060 PIN domain-like RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 Gene3D G3DSA:1.10.150.20 205 265 2.7E-25 T 10-03-2017 RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 Gene3D G3DSA:3.40.50.1010 34 204 2.6E-49 T 10-03-2017 IPR029060 PIN domain-like RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 Hamap MF_01192 Flap endonuclease Xni [xni]. 32 281 46.064 T 10-03-2017 IPR022895 Flap endonuclease Xni GO:0048256 RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 190 279 4.9E-26 T 10-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 35 176 2.2E-28 T 10-03-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 SMART SM00279 192 227 2.0E-11 T 10-03-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 SMART SM00475 33 280 5.7E-110 T 10-03-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 RG49_RS21055 604f83967ce63204806a9db7cda7670e 281 SUPERFAMILY SSF47807 190 273 1.2E-23 T 10-03-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 RG49_RS02235 6e09c66423b1dbf1cd34840c761961fd 93 Gene3D G3DSA:1.10.260.40 8 77 2.0E-15 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02235 6e09c66423b1dbf1cd34840c761961fd 93 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 15 66 3.0E-9 T 10-03-2017 IPR031856 Putative bacterial antitoxin YdaS RG49_RS20665 6e26303fdb74dcabb9c5f33970749be4 166 Gene3D G3DSA:1.10.10.10 76 149 2.8E-7 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20665 6e26303fdb74dcabb9c5f33970749be4 166 SUPERFAMILY SSF46894 84 152 6.46E-10 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS20665 6e26303fdb74dcabb9c5f33970749be4 166 Pfam PF00196 Bacterial regulatory proteins, luxR family 96 146 3.0E-6 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS20665 6e26303fdb74dcabb9c5f33970749be4 166 SMART SM00421 93 149 0.0088 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS01365 7f0b657c1abe847f75166fa4410f4fbc 196 PIRSF PIRSF030780 1 195 1.2E-126 T 10-03-2017 IPR016956 Inner membrane protein YdjM RG49_RS01365 7f0b657c1abe847f75166fa4410f4fbc 196 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 161 5.4E-34 T 10-03-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase RG49_RS14660 2c163ba489b2be2474a547fc2c98b4ae 483 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 124 452 3.7E-58 T 10-03-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 RG49_RS14660 2c163ba489b2be2474a547fc2c98b4ae 483 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 8 94 3.8E-30 T 10-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 RG49_RS14660 2c163ba489b2be2474a547fc2c98b4ae 483 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 9 101 8.2E-18 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS14660 2c163ba489b2be2474a547fc2c98b4ae 483 Gene3D G3DSA:3.40.50.2300 3 108 3.6E-38 T 10-03-2017 RG49_RS14660 2c163ba489b2be2474a547fc2c98b4ae 483 Pfam PF02378 Phosphotransferase system, EIIC 134 406 6.0E-28 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS14660 2c163ba489b2be2474a547fc2c98b4ae 483 SUPERFAMILY SSF52794 6 106 1.33E-32 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS18665 c64901c38cc419fd95efac45ef8a5b3e 269 Pfam PF00005 ABC transporter 25 172 1.0E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS18665 c64901c38cc419fd95efac45ef8a5b3e 269 Gene3D G3DSA:3.40.50.300 7 238 3.3E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18665 c64901c38cc419fd95efac45ef8a5b3e 269 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS18665 c64901c38cc419fd95efac45ef8a5b3e 269 SMART SM00382 33 229 1.4E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS18665 c64901c38cc419fd95efac45ef8a5b3e 269 SUPERFAMILY SSF52540 8 237 4.35E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 TIGRFAM TIGR00067 glut_race: glutamate racemase 24 272 1.7E-97 T 10-03-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 Pfam PF01177 Asp/Glu/Hydantoin racemase 26 235 2.4E-25 T 10-03-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 SUPERFAMILY SSF53681 127 279 6.54E-33 T 10-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 SUPERFAMILY SSF53681 24 125 9.15E-31 T 10-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 89 97 - T 10-03-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 200 210 - T 10-03-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 Gene3D G3DSA:3.40.50.1860 22 191 7.1E-49 T 10-03-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS14270 491082b44bf46a95668a6816713fc15d 285 Hamap MF_00258 Glutamate racemase [murI]. 22 274 34.582 T 10-03-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 TIGRFAM TIGR01927 menC_gamma/gm+: o-succinylbenzoate synthase 7 306 6.6E-135 T 10-03-2017 RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 SUPERFAMILY SSF51604 104 307 2.49E-50 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 Pfam PF13378 Enolase C-terminal domain-like 124 279 2.0E-16 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 SUPERFAMILY SSF54826 1 97 3.49E-30 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 SMART SM00922 114 209 6.3E-11 T 10-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 Gene3D G3DSA:3.30.390.10 1 125 5.9E-49 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 4 317 22.914 T 10-03-2017 IPR010196 o-succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS23785 1fe0536e9c677f73701f2ab2f32fd868 320 Gene3D G3DSA:3.20.20.120 126 302 3.5E-36 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS15095 96b08e8d879df54df1aad668aa3ccad0 296 SUPERFAMILY SSF103481 187 285 5.75E-9 T 10-03-2017 RG49_RS15095 96b08e8d879df54df1aad668aa3ccad0 296 SUPERFAMILY SSF103481 42 145 1.83E-12 T 10-03-2017 RG49_RS15095 96b08e8d879df54df1aad668aa3ccad0 296 TIGRFAM TIGR00688 rarD: protein RarD 8 261 2.2E-118 T 10-03-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 RG49_RS15095 96b08e8d879df54df1aad668aa3ccad0 296 Pfam PF00892 EamA-like transporter family 9 142 6.5E-14 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS15095 96b08e8d879df54df1aad668aa3ccad0 296 Pfam PF00892 EamA-like transporter family 152 284 1.4E-6 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS18680 f9202d3d2ddea3d73ae6e3b73b4adb52 211 PIRSF PIRSF004649 1 211 3.3E-64 T 10-03-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC RG49_RS18680 f9202d3d2ddea3d73ae6e3b73b4adb52 211 Gene3D G3DSA:3.10.450.50 26 70 4.8E-18 T 10-03-2017 IPR032710 NTF2-like domain RG49_RS18680 f9202d3d2ddea3d73ae6e3b73b4adb52 211 Gene3D G3DSA:3.10.450.50 114 172 4.8E-18 T 10-03-2017 IPR032710 NTF2-like domain RG49_RS18680 f9202d3d2ddea3d73ae6e3b73b4adb52 211 Gene3D G3DSA:1.10.10.640 173 203 9.7E-22 T 10-03-2017 IPR023094 Toluene tolerance protein, alpha-helical RG49_RS18680 f9202d3d2ddea3d73ae6e3b73b4adb52 211 Gene3D G3DSA:1.10.10.640 71 111 9.7E-22 T 10-03-2017 IPR023094 Toluene tolerance protein, alpha-helical RG49_RS18680 f9202d3d2ddea3d73ae6e3b73b4adb52 211 Pfam PF05494 MlaC protein 33 198 1.1E-53 T 10-03-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC RG49_RS05130 979cd2af81043f185ecb1db9e1bd9b9c 119 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 10-03-2017 IPR019808 Histidine triad, conserved site RG49_RS05130 979cd2af81043f185ecb1db9e1bd9b9c 119 Gene3D G3DSA:3.30.428.10 3 110 5.6E-37 T 10-03-2017 IPR011146 HIT-like domain GO:0003824 RG49_RS05130 979cd2af81043f185ecb1db9e1bd9b9c 119 Pfam PF01230 HIT domain 13 109 1.2E-29 T 10-03-2017 IPR001310 Histidine triad (HIT) protein RG49_RS05130 979cd2af81043f185ecb1db9e1bd9b9c 119 PRINTS PR00332 Histidine triad family signature 6 22 7.3E-19 T 10-03-2017 IPR001310 Histidine triad (HIT) protein RG49_RS05130 979cd2af81043f185ecb1db9e1bd9b9c 119 PRINTS PR00332 Histidine triad family signature 95 105 7.3E-19 T 10-03-2017 IPR001310 Histidine triad (HIT) protein RG49_RS05130 979cd2af81043f185ecb1db9e1bd9b9c 119 PRINTS PR00332 Histidine triad family signature 27 45 7.3E-19 T 10-03-2017 IPR001310 Histidine triad (HIT) protein RG49_RS05130 979cd2af81043f185ecb1db9e1bd9b9c 119 SUPERFAMILY SSF54197 3 113 1.55E-34 T 10-03-2017 IPR011146 HIT-like domain GO:0003824 RG49_RS02610 d8009c56d33a24b4602e6da04481de82 472 SMART SM00267 292 465 8.9E-59 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02610 d8009c56d33a24b4602e6da04481de82 472 SUPERFAMILY SSF55073 308 463 3.3E-38 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS02610 d8009c56d33a24b4602e6da04481de82 472 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 303 463 8.1E-39 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02610 d8009c56d33a24b4602e6da04481de82 472 Gene3D G3DSA:3.30.70.270 305 464 1.4E-41 T 10-03-2017 RG49_RS02610 d8009c56d33a24b4602e6da04481de82 472 Pfam PF00990 Diguanylate cyclase, GGDEF domain 303 461 3.8E-42 T 10-03-2017 IPR000160 GGDEF domain RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 116 202 4.5E-18 T 10-03-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 4.3E-30 T 10-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 SUPERFAMILY SSF141734 6 122 7.45E-47 T 10-03-2017 RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 203 38.01 T 10-03-2017 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 18.187 T 10-03-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 5.0E-31 T 10-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 SUPERFAMILY SSF101386 115 202 3.27E-23 T 10-03-2017 RG49_RS25070 1bf49514919c8c446ec3529084f0b5f8 203 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 105 2.0E-25 T 10-03-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 Pfam PF00330 Aconitase family (aconitate hydratase) 69 562 2.5E-183 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 ProSitePatterns PS01244 Aconitase family signature 2. 493 506 - T 10-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 SUPERFAMILY SSF52016 630 890 1.51E-90 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 890 0.0 T 10-03-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 Gene3D G3DSA:3.30.499.10 22 249 2.4E-78 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 Gene3D G3DSA:3.30.499.10 369 575 5.9E-62 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 Gene3D G3DSA:3.20.19.10 636 890 5.0E-84 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 Pfam PF00694 Aconitase C-terminal domain 691 818 1.2E-51 T 10-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 SUPERFAMILY SSF53732 10 625 1.96E-224 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 Gene3D G3DSA:3.40.1060.10 250 367 8.4E-37 T 10-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 217 232 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 431 442 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 279 292 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 293 306 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 146 159 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 203 216 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 493 506 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 170 178 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 PRINTS PR00415 Aconitase family signature 372 386 1.5E-42 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS04180 f0ca9a258fce93481693a94c67f6444b 891 ProSitePatterns PS00450 Aconitase family signature 1. 427 443 - T 10-03-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 RG49_RS17365 58a681b19f92ace93e3e1c4ad0efcd97 392 Pfam PF05638 Type VI secretion system effector, Hcp 27 139 2.9E-9 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS17365 58a681b19f92ace93e3e1c4ad0efcd97 392 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 147 5.0E-34 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS17365 58a681b19f92ace93e3e1c4ad0efcd97 392 Pfam PF12639 DNase/tRNase domain of colicin-like bacteriocin 272 350 6.4E-5 T 10-03-2017 IPR024622 Colicin/pyocin, DNase domain GO:0004519 RG49_RS17365 58a681b19f92ace93e3e1c4ad0efcd97 392 Gene3D G3DSA:2.30.110.20 1 144 7.6E-7 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS17365 58a681b19f92ace93e3e1c4ad0efcd97 392 SUPERFAMILY SSF141452 5 148 7.98E-23 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS17365 58a681b19f92ace93e3e1c4ad0efcd97 392 SUPERFAMILY SSF54060 244 348 1.65E-20 T 10-03-2017 RG49_RS16150 4181cf83cf26ea2fecc18adef347d76c 91 Gene3D G3DSA:3.90.940.10 1 78 2.6E-15 T 10-03-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 RG49_RS16150 4181cf83cf26ea2fecc18adef347d76c 91 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.321 T 10-03-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS16150 4181cf83cf26ea2fecc18adef347d76c 91 SMART SM01409 8 61 1.3E-15 T 10-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 RG49_RS16150 4181cf83cf26ea2fecc18adef347d76c 91 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 1.7E-30 T 10-03-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 RG49_RS16150 4181cf83cf26ea2fecc18adef347d76c 91 SUPERFAMILY SSF63562 1 79 8.2E-25 T 10-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 RG49_RS16150 4181cf83cf26ea2fecc18adef347d76c 91 Pfam PF01192 RNA polymerase Rpb6 10 59 1.6E-15 T 10-03-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 Pfam PF00072 Response regulator receiver domain 4 114 4.0E-27 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 7.9E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 7.9E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 7.9E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 Gene3D G3DSA:3.40.50.2300 2 113 9.0E-23 T 10-03-2017 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 Gene3D G3DSA:1.10.10.10 114 203 5.9E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 ProSitePatterns PS00622 LuxR-type HTH domain signature. 158 185 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 SMART SM00421 141 198 2.1E-20 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 SMART SM00448 1 113 1.1E-22 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 SUPERFAMILY SSF52172 1 124 1.85E-23 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 198 5.0E-22 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS23305 0fc39431cf45f67ef9e76c9a1f225d7f 204 SUPERFAMILY SSF46894 134 202 1.73E-17 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS00995 6b2a44725c222898af8834d81fe2c51f 60 SUPERFAMILY SSF103063 1 60 3.01E-32 T 10-03-2017 IPR015051 Protein YoaG RG49_RS00995 6b2a44725c222898af8834d81fe2c51f 60 Pfam PF08956 Domain of unknown function (DUF1869) 3 60 5.3E-32 T 10-03-2017 IPR015051 Protein YoaG RG49_RS00995 6b2a44725c222898af8834d81fe2c51f 60 Gene3D G3DSA:3.30.160.220 1 60 2.8E-36 T 10-03-2017 IPR015051 Protein YoaG RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 7 517 4.5E-189 T 10-03-2017 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 SUPERFAMILY SSF69279 7 185 2.51E-49 T 10-03-2017 RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 SUPERFAMILY SSF69349 439 666 3.69E-41 T 10-03-2017 RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 Gene3D G3DSA:2.40.50.230 367 448 3.3E-40 T 10-03-2017 IPR006531 Gp5 N-terminal RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 SUPERFAMILY SSF69255 361 448 1.39E-32 T 10-03-2017 RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 Gene3D G3DSA:3.55.50.10 97 191 4.8E-32 T 10-03-2017 RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 Pfam PF05954 Phage late control gene D protein (GPD) 28 328 7.5E-73 T 10-03-2017 RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 20 500 1.8E-134 T 10-03-2017 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein RG49_RS03100 cba0514c415f05275cf92b2e7d4363b1 702 SUPERFAMILY SSF69279 188 362 3.15E-44 T 10-03-2017 RG49_RS21170 be27e644b13994f36f3bfab71de706cc 223 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 223 40.34 T 10-03-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 RG49_RS21170 be27e644b13994f36f3bfab71de706cc 223 Gene3D G3DSA:3.20.20.70 29 136 1.3E-7 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS21170 be27e644b13994f36f3bfab71de706cc 223 Pfam PF04055 Radical SAM superfamily 27 132 3.1E-8 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS21170 be27e644b13994f36f3bfab71de706cc 223 PIRSF PIRSF000370 1 223 2.5E-72 T 10-03-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 RG49_RS21170 be27e644b13994f36f3bfab71de706cc 223 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 9 223 2.7E-111 T 10-03-2017 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 RG49_RS21170 be27e644b13994f36f3bfab71de706cc 223 SUPERFAMILY SSF102114 24 119 3.79E-7 T 10-03-2017 RG49_RS21170 be27e644b13994f36f3bfab71de706cc 223 Pfam PF13394 4Fe-4S single cluster domain 24 128 1.1E-13 T 10-03-2017 RG49_RS01350 f3ddecb1842fbbf905ff46d1a0f478d3 87 Pfam PF10729 Cell division activator CedA 10 85 9.3E-46 T 10-03-2017 IPR019666 Cell division activator CedA GO:0003677|GO:0051301 RG49_RS01350 f3ddecb1842fbbf905ff46d1a0f478d3 87 Hamap MF_01580 Cell division activator CedA [cedA]. 8 87 36.751 T 10-03-2017 IPR019666 Cell division activator CedA GO:0003677|GO:0051301 RG49_RS18910 597465296a5de04a017204cb6868199c 196 Hamap MF_01157 DnaA initiator-associating protein DiaA [diaA]. 1 196 63.307 T 10-03-2017 IPR023070 DnaA initiator-associating protein RG49_RS18910 597465296a5de04a017204cb6868199c 196 SUPERFAMILY SSF53697 2 191 1.27E-51 T 10-03-2017 RG49_RS18910 597465296a5de04a017204cb6868199c 196 Pfam PF13580 SIS domain 9 144 4.4E-33 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS18910 597465296a5de04a017204cb6868199c 196 Gene3D G3DSA:3.40.50.10490 2 191 6.4E-56 T 10-03-2017 RG49_RS01940 b5e3262b9cb7edf937e0c406173a445e 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 4.3E-25 T 10-03-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 RG49_RS01940 b5e3262b9cb7edf937e0c406173a445e 346 SUPERFAMILY SSF51735 2 192 1.67E-50 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01940 b5e3262b9cb7edf937e0c406173a445e 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 241 2.3E-19 T 10-03-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 RG49_RS01940 b5e3262b9cb7edf937e0c406173a445e 346 Gene3D G3DSA:3.30.360.10 130 339 2.5E-30 T 10-03-2017 RG49_RS01940 b5e3262b9cb7edf937e0c406173a445e 346 Gene3D G3DSA:3.40.50.720 1 129 5.7E-42 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06475 5c8582d7e6f35166b358ca79e5b5c576 162 Pfam PF10767 Protein of unknown function (DUF2593) 21 160 3.7E-63 T 10-03-2017 IPR019703 Protein of unknown function DUF2593 RG49_RS07735 958ba29334f789f470d07397b634d739 406 Pfam PF00480 ROK family 89 392 2.4E-102 T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS07735 958ba29334f789f470d07397b634d739 406 Pfam PF01047 MarR family 25 63 5.5E-7 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS07735 958ba29334f789f470d07397b634d739 406 SUPERFAMILY SSF53067 88 394 8.64E-56 T 10-03-2017 RG49_RS07735 958ba29334f789f470d07397b634d739 406 Gene3D G3DSA:1.10.10.10 14 79 2.9E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07735 958ba29334f789f470d07397b634d739 406 Gene3D G3DSA:3.30.420.40 225 376 1.0E-47 T 10-03-2017 RG49_RS07735 958ba29334f789f470d07397b634d739 406 Gene3D G3DSA:3.30.420.40 85 224 2.4E-34 T 10-03-2017 RG49_RS07735 958ba29334f789f470d07397b634d739 406 SUPERFAMILY SSF46785 14 79 5.25E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07735 958ba29334f789f470d07397b634d739 406 ProSitePatterns PS01125 ROK family signature. 220 247 - T 10-03-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 RG49_RS09975 4c3b49e1637d8ffe03f7ec30e3b112ee 54 Pfam PF13817 IS66 C-terminal element 12 49 1.0E-16 T 10-03-2017 RG49_RS22185 6a47864645205b02d31d4491088179b7 318 Pfam PF03888 MucB/RseB N-terminal domain 28 197 8.7E-62 T 10-03-2017 IPR033434 MucB/RseB, N-terminal RG49_RS22185 6a47864645205b02d31d4491088179b7 318 PIRSF PIRSF005427 1 318 1.9E-102 T 10-03-2017 IPR005588 MucB/RseB RG49_RS22185 6a47864645205b02d31d4491088179b7 318 Pfam PF17188 MucB/RseB C-terminal domain 217 313 2.0E-29 T 10-03-2017 IPR033436 MucB/RseB, C-terminal RG49_RS22185 6a47864645205b02d31d4491088179b7 318 Gene3D G3DSA:2.50.20.10 41 193 7.3E-8 T 10-03-2017 RG49_RS09545 f363ddee906967b072592307902fbf73 287 Pfam PF11392 Protein of unknown function (DUF2877) 167 274 5.8E-27 T 10-03-2017 IPR021530 Protein of unknown function DUF2877 RG49_RS15585 89f4e395d961f21495741ae5f17800b1 257 SUPERFAMILY SSF52540 11 243 2.66E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15585 89f4e395d961f21495741ae5f17800b1 257 SMART SM00382 35 237 1.0E-10 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15585 89f4e395d961f21495741ae5f17800b1 257 Gene3D G3DSA:3.40.50.300 11 251 1.5E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15585 89f4e395d961f21495741ae5f17800b1 257 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 11 257 1.6E-121 T 10-03-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 RG49_RS15585 89f4e395d961f21495741ae5f17800b1 257 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS15585 89f4e395d961f21495741ae5f17800b1 257 Pfam PF00005 ABC transporter 26 181 1.4E-34 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS00235 2a64dc7cb9c3fe98c426f24ae9c9efb9 222 SUPERFAMILY SSF143081 2 222 9.16E-61 T 10-03-2017 IPR003738 SOS response associated peptidase (SRAP) RG49_RS00235 2a64dc7cb9c3fe98c426f24ae9c9efb9 222 Pfam PF02586 SOS response associated peptidase (SRAP) 1 211 5.7E-49 T 10-03-2017 IPR003738 SOS response associated peptidase (SRAP) RG49_RS00235 2a64dc7cb9c3fe98c426f24ae9c9efb9 222 Gene3D G3DSA:3.90.1680.10 1 222 1.3E-66 T 10-03-2017 IPR003738 SOS response associated peptidase (SRAP) RG49_RS01320 a0de2a6a74b4128dddc5bc89c77b6413 116 SUPERFAMILY SSF46973 14 113 5.36E-34 T 10-03-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 RG49_RS01320 a0de2a6a74b4128dddc5bc89c77b6413 116 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 19 112 2.0E-32 T 10-03-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 RG49_RS01320 a0de2a6a74b4128dddc5bc89c77b6413 116 TIGRFAM TIGR00823 EIIA-LAC: PTS system, lactose-specific IIa component 15 113 1.6E-41 T 10-03-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 RG49_RS01320 a0de2a6a74b4128dddc5bc89c77b6413 116 PIRSF PIRSF000699 10 116 6.3E-41 T 10-03-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 RG49_RS01320 a0de2a6a74b4128dddc5bc89c77b6413 116 Gene3D G3DSA:1.20.58.80 14 115 7.6E-42 T 10-03-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 RG49_RS08165 5b883d2a2c2e9dc076f0d304176c5452 391 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 101 387 1.8E-84 T 10-03-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 RG49_RS08165 5b883d2a2c2e9dc076f0d304176c5452 391 Pfam PF00425 chorismate binding enzyme 126 380 7.0E-69 T 10-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal RG49_RS08165 5b883d2a2c2e9dc076f0d304176c5452 391 SUPERFAMILY SSF56322 13 389 9.68E-88 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS08165 5b883d2a2c2e9dc076f0d304176c5452 391 Gene3D G3DSA:3.60.120.10 99 389 2.7E-82 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS02095 7e07ed9ac6f27aa9a93d46e5913731ee 417 Gene3D G3DSA:1.20.1250.20 236 412 2.2E-17 T 10-03-2017 RG49_RS02095 7e07ed9ac6f27aa9a93d46e5913731ee 417 Gene3D G3DSA:1.20.1250.20 36 216 2.2E-32 T 10-03-2017 RG49_RS02095 7e07ed9ac6f27aa9a93d46e5913731ee 417 SUPERFAMILY SSF103473 27 414 1.57E-64 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS02095 7e07ed9ac6f27aa9a93d46e5913731ee 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 91 107 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS02095 7e07ed9ac6f27aa9a93d46e5913731ee 417 Pfam PF07690 Major Facilitator Superfamily 41 260 3.3E-27 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS23355 a0b8c87e2bd67ace085e12beedceb233 446 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 17 446 1.1E-155 T 10-03-2017 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) RG49_RS23355 a0b8c87e2bd67ace085e12beedceb233 446 Gene3D G3DSA:2.40.160.60 26 446 2.1E-141 T 10-03-2017 RG49_RS23355 a0b8c87e2bd67ace085e12beedceb233 446 SUPERFAMILY SSF56935 26 446 1.1E-114 T 10-03-2017 RG49_RS24510 cd1b4a7a95d01231f15e0d49778abb57 313 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 264 2.8E-89 T 10-03-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 RG49_RS24510 cd1b4a7a95d01231f15e0d49778abb57 313 Gene3D G3DSA:3.40.710.10 21 280 1.8E-65 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS24510 cd1b4a7a95d01231f15e0d49778abb57 313 SUPERFAMILY SSF56601 6 280 1.04E-61 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS24510 cd1b4a7a95d01231f15e0d49778abb57 313 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 69 80 1.9E-13 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS24510 cd1b4a7a95d01231f15e0d49778abb57 313 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 119 136 1.9E-13 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS24510 cd1b4a7a95d01231f15e0d49778abb57 313 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 146 159 1.9E-13 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS10615 63f18babb1313bc1324b3528169bfcea 172 Gene3D G3DSA:2.30.110.20 1 166 4.2E-31 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS10615 63f18babb1313bc1324b3528169bfcea 172 SUPERFAMILY SSF141452 3 168 1.57E-37 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS10615 63f18babb1313bc1324b3528169bfcea 172 Pfam PF05638 Type VI secretion system effector, Hcp 8 155 6.1E-31 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS10615 63f18babb1313bc1324b3528169bfcea 172 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 168 4.4E-62 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS07285 9ed734d2db599900373bfc93276f57e3 313 Pfam PF01545 Cation efflux family 22 213 1.1E-51 T 10-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 RG49_RS07285 9ed734d2db599900373bfc93276f57e3 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 18 293 2.3E-102 T 10-03-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 RG49_RS07285 9ed734d2db599900373bfc93276f57e3 313 Hamap MF_00552 Zinc transporter ZitB [zitB]. 3 312 66.892 T 10-03-2017 IPR023500 Zinc transporter ZitB GO:0005385|GO:0006829|GO:0016020 RG49_RS07285 9ed734d2db599900373bfc93276f57e3 313 SUPERFAMILY SSF161111 16 214 9.55E-61 T 10-03-2017 RG49_RS07285 9ed734d2db599900373bfc93276f57e3 313 Gene3D G3DSA:3.30.70.1350 227 290 7.8E-4 T 10-03-2017 IPR027470 Cation efflux protein, cytoplasmic domain RG49_RS07285 9ed734d2db599900373bfc93276f57e3 313 SUPERFAMILY SSF160240 227 292 1.05E-9 T 10-03-2017 RG49_RS07285 9ed734d2db599900373bfc93276f57e3 313 Gene3D G3DSA:1.20.1510.10 18 213 1.3E-67 T 10-03-2017 IPR027469 Cation efflux protein transmembrane domain RG49_RS14960 fa9308178591639f73f3fa408accec78 729 SUPERFAMILY SSF52096 3 303 6.36E-68 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS14960 fa9308178591639f73f3fa408accec78 729 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 10-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 493 517 - T 10-03-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 SUPERFAMILY SSF51735 314 495 4.32E-57 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Gene3D G3DSA:3.90.226.10 14 201 8.2E-59 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Gene3D G3DSA:3.90.226.10 235 296 8.2E-59 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Gene3D G3DSA:1.10.1040.10 632 710 2.0E-16 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 SUPERFAMILY SSF48179 495 610 1.87E-28 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 714 0.0 T 10-03-2017 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 627 690 6.8E-5 T 10-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 496 592 2.0E-26 T 10-03-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Gene3D G3DSA:1.10.1040.10 498 593 2.5E-21 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 316 494 3.2E-60 T 10-03-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 205 6.7E-37 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Hamap MF_01621 Fatty acid oxidation complex subunit alpha [fadB]. 1 715 53.578 T 10-03-2017 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 RG49_RS14960 fa9308178591639f73f3fa408accec78 729 Gene3D G3DSA:3.40.50.720 304 497 3.0E-62 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS14960 fa9308178591639f73f3fa408accec78 729 SUPERFAMILY SSF48179 622 714 2.13E-22 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS05445 ff868b3e5174eae1e4b69f228cbb012e 151 Pfam PF07012 Curlin associated repeat 75 106 3.5E-10 T 10-03-2017 IPR009742 Curlin associated GO:0007155|GO:0009289 RG49_RS05445 ff868b3e5174eae1e4b69f228cbb012e 151 Pfam PF07012 Curlin associated repeat 100 130 1.9E-8 T 10-03-2017 IPR009742 Curlin associated GO:0007155|GO:0009289 RG49_RS05445 ff868b3e5174eae1e4b69f228cbb012e 151 Pfam PF07012 Curlin associated repeat 53 86 4.6E-7 T 10-03-2017 IPR009742 Curlin associated GO:0007155|GO:0009289 RG49_RS15470 224c9b5cddbe7cce94d4b0d9efb673f8 139 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 139 33.417 T 10-03-2017 IPR023064 D-ribose pyranase GO:0016872 RG49_RS15470 224c9b5cddbe7cce94d4b0d9efb673f8 139 Gene3D G3DSA:3.40.1650.10 1 139 4.4E-45 T 10-03-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 RG49_RS15470 224c9b5cddbe7cce94d4b0d9efb673f8 139 Pfam PF05025 RbsD / FucU transport protein family 1 138 2.6E-48 T 10-03-2017 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 RG49_RS15470 224c9b5cddbe7cce94d4b0d9efb673f8 139 SUPERFAMILY SSF102546 1 139 4.45E-45 T 10-03-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 SUPERFAMILY SSF53383 20 401 8.34E-126 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 Gene3D G3DSA:3.90.1150.10 290 403 5.0E-36 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 17 400 8.0E-150 T 10-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 8 404 9.0E-205 T 10-03-2017 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 Pfam PF00202 Aminotransferase class-III 26 400 2.8E-142 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 Gene3D G3DSA:3.40.640.10 60 289 6.2E-92 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS17795 7049391234215ade9ea104bab730f6f0 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 14 401 45.823 T 10-03-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 RG49_RS08545 bc1e5610375e5b8c177351ff78cf0a56 160 Pfam PF04115 Ureidoglycolate lyase 2 154 1.2E-45 T 10-03-2017 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 RG49_RS08545 bc1e5610375e5b8c177351ff78cf0a56 160 Gene3D G3DSA:2.60.120.480 2 155 5.2E-53 T 10-03-2017 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 RG49_RS08545 bc1e5610375e5b8c177351ff78cf0a56 160 PIRSF PIRSF017306 1 160 5.7E-109 T 10-03-2017 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 RG49_RS08545 bc1e5610375e5b8c177351ff78cf0a56 160 SUPERFAMILY SSF51182 2 156 2.0E-54 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS08545 bc1e5610375e5b8c177351ff78cf0a56 160 Hamap MF_00616 Ureidoglycolate lyase [allA]. 1 160 37.868 T 10-03-2017 IPR023525 Ureidoglycolate lyase, bacterial GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 RG49_RS16420 c6deb7847a6f01c74734deeba375556a 195 Pfam PF05068 Mannitol repressor 29 187 1.3E-62 T 10-03-2017 IPR007761 Mannitol repressor RG49_RS16420 c6deb7847a6f01c74734deeba375556a 195 Gene3D G3DSA:1.20.120.330 21 188 1.5E-79 T 10-03-2017 RG49_RS16420 c6deb7847a6f01c74734deeba375556a 195 SUPERFAMILY SSF158668 26 187 6.41E-59 T 10-03-2017 RG49_RS14290 4a18fe7c691fd8116f967c88d2d181cf 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 77 3.9E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS14290 4a18fe7c691fd8116f967c88d2d181cf 234 Gene3D G3DSA:1.10.357.10 21 212 3.3E-35 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS14290 4a18fe7c691fd8116f967c88d2d181cf 234 SUPERFAMILY SSF46689 20 96 7.56E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS14290 4a18fe7c691fd8116f967c88d2d181cf 234 Hamap MF_01190 HTH-type transcriptional repressor FabR [fabR]. 20 229 55.323 T 10-03-2017 IPR023764 Transcriptional repressor HTH, FabR RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 SUPERFAMILY SSF52540 241 485 2.51E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 Gene3D G3DSA:3.40.50.300 3 233 1.0E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 SUPERFAMILY SSF52540 3 228 3.48E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 SMART SM00382 286 482 1.0E-6 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 SMART SM00382 29 219 2.0E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 Gene3D G3DSA:3.40.50.300 249 504 1.2E-52 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 TIGRFAM TIGR02633 xylG: D-xylose ABC transporter, ATP-binding protein 4 502 7.8E-292 T 10-03-2017 IPR013455 ABC transporter, D-xylose, ATP-binding protein GO:0005524|GO:0015614|GO:0015753|GO:0016020 RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 Pfam PF00005 ABC transporter 21 171 6.7E-29 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS16615 ffde89a8304bd686e893a0411998a683 513 Pfam PF00005 ABC transporter 278 433 2.6E-21 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS22695 64c36310818379acae763dab37527c29 670 SUPERFAMILY SSF52540 346 583 1.73E-75 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22695 64c36310818379acae763dab37527c29 670 SMART SM00065 169 321 9.3E-20 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS22695 64c36310818379acae763dab37527c29 670 Pfam PF00158 Sigma-54 interaction domain 347 513 5.3E-73 T 10-03-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 RG49_RS22695 64c36310818379acae763dab37527c29 670 Gene3D G3DSA:3.30.450.40 147 323 6.8E-17 T 10-03-2017 IPR029016 GAF domain-like RG49_RS22695 64c36310818379acae763dab37527c29 670 Pfam PF02954 Bacterial regulatory protein, Fis family 621 662 1.2E-4 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS22695 64c36310818379acae763dab37527c29 670 Gene3D G3DSA:3.40.50.300 345 519 2.4E-62 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22695 64c36310818379acae763dab37527c29 670 Gene3D G3DSA:1.10.8.60 520 572 3.1E-24 T 10-03-2017 RG49_RS22695 64c36310818379acae763dab37527c29 670 Pfam PF13185 GAF domain 168 311 2.8E-11 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS22695 64c36310818379acae763dab37527c29 670 SUPERFAMILY SSF46689 560 664 1.39E-5 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS22695 64c36310818379acae763dab37527c29 670 SUPERFAMILY SSF55781 151 328 6.98E-18 T 10-03-2017 IPR029016 GAF domain-like RG49_RS22695 64c36310818379acae763dab37527c29 670 Gene3D G3DSA:1.10.10.60 573 664 1.9E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS22695 64c36310818379acae763dab37527c29 670 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 560 569 - T 10-03-2017 IPR025944 Sigma-54 interaction domain, conserved site RG49_RS22695 64c36310818379acae763dab37527c29 670 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 371 384 - T 10-03-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 RG49_RS22695 64c36310818379acae763dab37527c29 670 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 433 448 - T 10-03-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 RG49_RS22695 64c36310818379acae763dab37527c29 670 SMART SM00382 367 511 1.5E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06515 03bc60d22bbef4fb47c40413718dd28a 240 SUPERFAMILY SSF55469 1 239 6.41E-74 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS06515 03bc60d22bbef4fb47c40413718dd28a 240 PIRSF PIRSF005426 1 240 3.0E-82 T 10-03-2017 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 RG49_RS06515 03bc60d22bbef4fb47c40413718dd28a 240 Pfam PF00881 Nitroreductase family 11 159 2.7E-17 T 10-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 RG49_RS06515 03bc60d22bbef4fb47c40413718dd28a 240 Gene3D G3DSA:3.40.109.10 2 239 2.0E-74 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS12210 0ab949dcffc99c2a0c1de1db8fadb33f 267 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 265 1.5E-6 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS12210 0ab949dcffc99c2a0c1de1db8fadb33f 267 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 267 2.4E-140 T 10-03-2017 IPR012690 2-oxo-hepta-3-ene-1,7-dioic acid hydratase GO:0019439 RG49_RS12210 0ab949dcffc99c2a0c1de1db8fadb33f 267 SUPERFAMILY SSF56529 3 267 1.96E-77 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS12210 0ab949dcffc99c2a0c1de1db8fadb33f 267 Gene3D G3DSA:3.90.850.10 2 267 1.4E-86 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 Pfam PF00664 ABC transporter transmembrane region 26 291 2.9E-49 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 Pfam PF00005 ABC transporter 369 513 1.1E-27 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 SMART SM00382 375 560 4.0E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 21 556 6.2E-189 T 10-03-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 SUPERFAMILY SSF52540 350 582 1.94E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 SUPERFAMILY SSF90123 11 331 3.14E-54 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 Gene3D G3DSA:3.40.50.300 350 572 6.7E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06305 24e25a47d90dabe8d4e1782aac5cb482 588 Gene3D G3DSA:1.20.1560.10 21 335 2.5E-45 T 10-03-2017 RG49_RS14130 3d4d07c6d0201932400ae28cc925d661 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 66 3.7E-20 T 10-03-2017 IPR010035 ThiS, thiamine-biosynthesis RG49_RS14130 3d4d07c6d0201932400ae28cc925d661 66 Pfam PF02597 ThiS family 3 66 1.1E-17 T 10-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 RG49_RS14130 3d4d07c6d0201932400ae28cc925d661 66 Gene3D G3DSA:3.10.20.30 1 66 2.1E-25 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS14130 3d4d07c6d0201932400ae28cc925d661 66 SUPERFAMILY SSF54285 1 66 9.74E-19 T 10-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp RG49_RS03350 231cde29fd90ffdeb0d36f6deea14d2e 479 Gene3D G3DSA:3.40.605.10 5 264 2.9E-92 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03350 231cde29fd90ffdeb0d36f6deea14d2e 479 Pfam PF00171 Aldehyde dehydrogenase family 22 475 2.0E-165 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03350 231cde29fd90ffdeb0d36f6deea14d2e 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS03350 231cde29fd90ffdeb0d36f6deea14d2e 479 Gene3D G3DSA:3.40.309.10 265 439 7.6E-66 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS03350 231cde29fd90ffdeb0d36f6deea14d2e 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS03350 231cde29fd90ffdeb0d36f6deea14d2e 479 SUPERFAMILY SSF53720 4 477 3.67E-159 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 SUPERFAMILY SSF47384 194 271 6.47E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 SMART SM00304 158 210 2.5E-6 T 10-03-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 423 2.6E-17 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 SMART SM00388 211 271 5.3E-8 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 SUPERFAMILY SSF55874 261 424 1.44E-34 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 270 1.3E-7 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 Gene3D G3DSA:1.10.287.130 201 267 4.6E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 Gene3D G3DSA:3.30.565.10 274 425 1.1E-34 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 5.3E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 422 5.3E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 5.3E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 5.3E-13 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS02015 268ba1e22c5a3508626ec832304ceb98 433 SMART SM00387 315 425 2.2E-32 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS12340 1b7e077122e0b52bd4f6c01e2516c40a 184 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 8 182 32.667 T 10-03-2017 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 RG49_RS12340 1b7e077122e0b52bd4f6c01e2516c40a 184 SUPERFAMILY SSF56399 12 183 1.78E-52 T 10-03-2017 RG49_RS12340 1b7e077122e0b52bd4f6c01e2516c40a 184 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 11 175 1.1E-36 T 10-03-2017 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 RG49_RS02065 52f107aa3bfc6b6bbad5e7f58b07ac7e 121 Pfam PF00893 Small Multidrug Resistance protein 4 94 1.1E-25 T 10-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 RG49_RS02065 52f107aa3bfc6b6bbad5e7f58b07ac7e 121 SUPERFAMILY SSF103481 8 107 1.83E-16 T 10-03-2017 RG49_RS21685 0fcf2ace1d4b289de6ea8f93eeb079ff 394 Gene3D G3DSA:1.20.1250.20 218 386 8.3E-10 T 10-03-2017 RG49_RS21685 0fcf2ace1d4b289de6ea8f93eeb079ff 394 Pfam PF07690 Major Facilitator Superfamily 17 194 3.8E-24 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS21685 0fcf2ace1d4b289de6ea8f93eeb079ff 394 Pfam PF07690 Major Facilitator Superfamily 218 385 8.7E-11 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS21685 0fcf2ace1d4b289de6ea8f93eeb079ff 394 SUPERFAMILY SSF103473 9 388 2.09E-54 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS21685 0fcf2ace1d4b289de6ea8f93eeb079ff 394 Gene3D G3DSA:1.20.1250.20 10 189 8.7E-25 T 10-03-2017 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 Pfam PF01578 Cytochrome C assembly protein 9 184 1.3E-32 T 10-03-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 156 182 3.3E-64 T 10-03-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 62 82 3.3E-64 T 10-03-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 100 120 3.3E-64 T 10-03-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 121 141 3.3E-64 T 10-03-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 45 62 3.3E-64 T 10-03-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 201 225 3.3E-64 T 10-03-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS24145 6d7d675f418d05c29874944be89efc88 245 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 45 225 5.4E-85 T 10-03-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 RG49_RS19445 6eef03657d134c52e9725ddeea8523f6 205 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 184 4.7E-50 T 10-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 RG49_RS19445 6eef03657d134c52e9725ddeea8523f6 205 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 193 18.447 T 10-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 RG49_RS19445 6eef03657d134c52e9725ddeea8523f6 205 SMART SM01207 10 185 1.9E-86 T 10-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 RG49_RS19445 6eef03657d134c52e9725ddeea8523f6 205 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 195 8.0E-83 T 10-03-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 RG49_RS04170 395f94a9f33cf11ba3dcbc322e63ad12 254 Gene3D G3DSA:1.20.144.10 138 240 3.6E-29 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS04170 395f94a9f33cf11ba3dcbc322e63ad12 254 Gene3D G3DSA:1.20.144.10 32 106 3.6E-29 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS04170 395f94a9f33cf11ba3dcbc322e63ad12 254 SUPERFAMILY SSF48317 150 234 1.7E-32 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS04170 395f94a9f33cf11ba3dcbc322e63ad12 254 SUPERFAMILY SSF48317 16 118 1.7E-32 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS04170 395f94a9f33cf11ba3dcbc322e63ad12 254 SMART SM00014 77 227 6.0E-49 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS04170 395f94a9f33cf11ba3dcbc322e63ad12 254 Pfam PF01569 PAP2 superfamily 79 232 1.5E-34 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS21800 58c5af2a91415ec158aec37e66731cc6 98 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 1 86 6.4E-7 T 10-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS21800 58c5af2a91415ec158aec37e66731cc6 98 ProDom PD063434 ENZYME ECS3519 YQAD 9 98 7.0E-45 T 10-03-2017 IPR020316 Uncharacterised protein family YgaQ RG49_RS21800 58c5af2a91415ec158aec37e66731cc6 98 SUPERFAMILY SSF51011 2 86 6.68E-10 T 10-03-2017 RG49_RS21800 58c5af2a91415ec158aec37e66731cc6 98 Gene3D G3DSA:2.60.40.1180 1 86 7.1E-8 T 10-03-2017 IPR013780 Glycosyl hydrolase, all-beta RG49_RS17710 cd0a3106b6e5ec18f1b48d793f609653 361 SUPERFAMILY SSF53383 33 342 2.45E-31 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS17710 cd0a3106b6e5ec18f1b48d793f609653 361 Pfam PF00155 Aminotransferase class I and II 54 232 6.5E-9 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS17710 cd0a3106b6e5ec18f1b48d793f609653 361 Gene3D G3DSA:3.40.640.10 33 238 3.1E-22 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS02385 e105ce00a64f3d90ee69817da8ec8f06 700 Pfam PF05876 Phage terminase large subunit (GpA) 34 644 1.3E-175 T 10-03-2017 IPR008866 Bacteriophage lambda, GpA RG49_RS11030 0e6003b175c65911bc68fb215270015c 232 SUPERFAMILY SSF53167 1 229 4.32E-75 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS11030 0e6003b175c65911bc68fb215270015c 232 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 229 47.921 T 10-03-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS11030 0e6003b175c65911bc68fb215270015c 232 Gene3D G3DSA:3.40.50.1580 1 229 4.2E-77 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS11030 0e6003b175c65911bc68fb215270015c 232 Pfam PF01048 Phosphorylase superfamily 2 226 6.2E-49 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS11030 0e6003b175c65911bc68fb215270015c 232 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 9.6E-138 T 10-03-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 RG49_RS15090 7dd21fe7171c9e259c7ece19b5ba22f4 155 Pfam PF03061 Thioesterase superfamily 57 145 4.5E-19 T 10-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 RG49_RS15090 7dd21fe7171c9e259c7ece19b5ba22f4 155 Gene3D G3DSA:3.10.129.10 17 154 7.0E-31 T 10-03-2017 IPR029069 HotDog domain RG49_RS15090 7dd21fe7171c9e259c7ece19b5ba22f4 155 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 25 153 5.2E-15 T 10-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 RG49_RS15090 7dd21fe7171c9e259c7ece19b5ba22f4 155 SUPERFAMILY SSF54637 12 154 1.1E-25 T 10-03-2017 IPR029069 HotDog domain RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 PRINTS PR00394 RHS protein signature 215 235 1.1E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 PRINTS PR00394 RHS protein signature 177 196 1.1E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 PRINTS PR00394 RHS protein signature 270 290 1.1E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 PRINTS PR00394 RHS protein signature 293 312 1.1E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 PRINTS PR00394 RHS protein signature 246 261 1.1E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 Pfam PF03527 RHS protein 221 258 2.5E-14 T 10-03-2017 IPR001826 RHS protein RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 Pfam PF05593 RHS Repeat 17 62 5.0E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS07580 542a3fa26fa0556d26a74c9d3509a2ae 477 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 248 325 5.4E-24 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS19510 28efdce60777854550935d65f4c0e5f5 66 SUPERFAMILY SSF109747 1 66 1.44E-43 T 10-03-2017 IPR015065 Surface composition regulator RG49_RS19510 28efdce60777854550935d65f4c0e5f5 66 Pfam PF08971 Glycogen synthesis protein 1 66 4.2E-41 T 10-03-2017 IPR015065 Surface composition regulator RG49_RS19510 28efdce60777854550935d65f4c0e5f5 66 ProDom PD054490 GLYCOGEN GLGS SYNTHESIS BIOSYNTHESIS DEPENDENT BIOSYNTHESIS RPOS 3D-STRUCTURE 1 66 4.0E-34 T 10-03-2017 IPR015065 Surface composition regulator RG49_RS19510 28efdce60777854550935d65f4c0e5f5 66 Hamap MF_00525 Surface composition regulator [glgS]. 1 59 20.031 T 10-03-2017 IPR015065 Surface composition regulator RG49_RS19510 28efdce60777854550935d65f4c0e5f5 66 Gene3D G3DSA:1.20.970.20 1 66 1.9E-40 T 10-03-2017 IPR015065 Surface composition regulator RG49_RS11305 b8adf77916259d7103ab136bcf59a655 284 Pfam PF17113 Regulatory signalling modulator protein AmpE 1 284 8.5E-159 T 10-03-2017 IPR031347 Protein AmpE RG49_RS14000 8b9be9c80db3d271bd73dd7b1e08fe27 533 Gene3D G3DSA:1.20.1220.12 414 526 3.0E-38 T 10-03-2017 RG49_RS14000 8b9be9c80db3d271bd73dd7b1e08fe27 533 Gene3D G3DSA:3.20.20.360 73 413 1.8E-123 T 10-03-2017 RG49_RS14000 8b9be9c80db3d271bd73dd7b1e08fe27 533 Pfam PF01274 Malate synthase 12 532 1.7E-214 T 10-03-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS14000 8b9be9c80db3d271bd73dd7b1e08fe27 533 SUPERFAMILY SSF51645 9 532 3.66E-191 T 10-03-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS14000 8b9be9c80db3d271bd73dd7b1e08fe27 533 PIRSF PIRSF001363 2 533 1.3E-252 T 10-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS14000 8b9be9c80db3d271bd73dd7b1e08fe27 533 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 24 532 5.8E-251 T 10-03-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS14000 8b9be9c80db3d271bd73dd7b1e08fe27 533 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 10-03-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 SMART SM00411 1 90 7.6E-43 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.2E-33 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 10-03-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 SUPERFAMILY SSF47729 1 90 4.27E-32 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 7.0E-20 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 7.0E-20 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 7.0E-20 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS08920 f6fe331eede1004b86965d42acd8bb28 90 Gene3D G3DSA:4.10.520.10 1 90 1.2E-36 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 PIRSF PIRSF038994 1 382 3.7E-114 T 10-03-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 SUPERFAMILY SSF51338 1 53 3.24E-18 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 377 1.3E-183 T 10-03-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 Gene3D G3DSA:3.20.20.140 55 349 7.3E-97 T 10-03-2017 RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 Pfam PF01979 Amidohydrolase family 50 379 6.2E-48 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 SUPERFAMILY SSF51556 54 350 2.14E-101 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 Gene3D G3DSA:2.30.40.10 2 54 6.3E-9 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS07730 99cc4b579997db4877c55d5b424f3417 382 Gene3D G3DSA:2.30.40.10 350 366 6.3E-9 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS24200 050e85c2c0280cdc84a4e429da1237a5 586 SUPERFAMILY SSF53649 257 570 8.64E-54 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS24200 050e85c2c0280cdc84a4e429da1237a5 586 PIRSF PIRSF004950 6 586 2.8E-223 T 10-03-2017 IPR012159 Inner membrane protein YejM RG49_RS24200 050e85c2c0280cdc84a4e429da1237a5 586 Pfam PF11893 Domain of unknown function (DUF3413) 6 252 4.0E-106 T 10-03-2017 IPR024588 Inner membrane protein YejM, N-terminal RG49_RS24200 050e85c2c0280cdc84a4e429da1237a5 586 Gene3D G3DSA:3.40.720.10 261 520 5.2E-32 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS24200 050e85c2c0280cdc84a4e429da1237a5 586 Pfam PF00884 Sulfatase 260 500 1.7E-32 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS18310 1a5b4cfd7c254375c6ea0f23a4f8d07d 293 SUPERFAMILY SSF53335 42 291 4.7E-44 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS18310 1a5b4cfd7c254375c6ea0f23a4f8d07d 293 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 286 5.9E-128 T 10-03-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 RG49_RS18310 1a5b4cfd7c254375c6ea0f23a4f8d07d 293 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 292 1.0E-105 T 10-03-2017 RG49_RS18310 1a5b4cfd7c254375c6ea0f23a4f8d07d 293 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 292 33.609 T 10-03-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 RG49_RS18310 1a5b4cfd7c254375c6ea0f23a4f8d07d 293 PIRSF PIRSF000401 1 293 4.8E-94 T 10-03-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 RG49_RS18310 1a5b4cfd7c254375c6ea0f23a4f8d07d 293 Gene3D G3DSA:3.40.50.150 98 286 3.0E-41 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 SUPERFAMILY SSF46689 232 284 2.55E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 Gene3D G3DSA:2.60.120.10 30 89 4.2E-9 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 SUPERFAMILY SSF51182 21 94 7.12E-10 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 Gene3D G3DSA:1.10.10.60 233 283 5.3E-16 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 SUPERFAMILY SSF46689 179 230 3.9E-5 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 Pfam PF02311 AraC-like ligand binding domain 27 157 4.6E-12 T 10-03-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 Gene3D G3DSA:1.10.10.60 181 232 2.7E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 SMART SM00342 196 279 1.2E-27 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS01545 eeb10359211ecbd77c0faa15f78e866c 303 Pfam PF12833 Helix-turn-helix domain 202 281 1.7E-18 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 Gene3D G3DSA:2.170.130.10 32 192 1.9E-39 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 Gene3D G3DSA:2.40.170.20 196 747 4.5E-176 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 Pfam PF00593 TonB dependent receptor 510 745 3.7E-28 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 730 747 - T 10-03-2017 IPR010917 TonB-dependent receptor, conserved site RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 SUPERFAMILY SSF56935 68 747 1.95E-144 T 10-03-2017 RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 47 - T 10-03-2017 IPR010916 TonB box, conserved site RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 78 747 7.0E-207 T 10-03-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 RG49_RS11075 4a7e063be5d86ea0bb74e179eac7f14b 747 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 180 4.1E-20 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS21210 c317c829e12f496268bed2f3f3bfd3db 191 Gene3D G3DSA:3.20.20.400 3 186 1.0E-68 T 10-03-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 RG49_RS21210 c317c829e12f496268bed2f3f3bfd3db 191 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 12 184 8.8E-63 T 10-03-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 RG49_RS21210 c317c829e12f496268bed2f3f3bfd3db 191 PIRSF PIRSF016897 1 190 1.0E-68 T 10-03-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 RG49_RS21210 c317c829e12f496268bed2f3f3bfd3db 191 SUPERFAMILY SSF110391 11 185 2.75E-56 T 10-03-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 RG49_RS05375 3dd5ca176a8335918527f6e49d32cbc8 350 Hamap MF_00469 UPF0176 protein YceA [yceA]. 22 277 39.871 T 10-03-2017 IPR020936 Uncharacterised protein family UPF0176 RG49_RS05375 3dd5ca176a8335918527f6e49d32cbc8 350 Pfam PF12368 Rhodanase C-terminal 246 307 9.9E-19 T 10-03-2017 IPR022111 Rhodanase, C-terminal RG49_RS05375 3dd5ca176a8335918527f6e49d32cbc8 350 SMART SM00450 136 237 7.5E-25 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS05375 3dd5ca176a8335918527f6e49d32cbc8 350 SUPERFAMILY SSF52821 115 271 1.44E-32 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS05375 3dd5ca176a8335918527f6e49d32cbc8 350 Pfam PF00581 Rhodanese-like domain 138 233 1.2E-13 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS05375 3dd5ca176a8335918527f6e49d32cbc8 350 Gene3D G3DSA:3.40.250.10 117 242 1.2E-37 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS10465 13119f177bb40251c69d693b6a942708 367 PIRSF PIRSF000729 1 367 2.7E-147 T 10-03-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 Gene3D G3DSA:3.40.1160.10 3 260 1.3E-59 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS10465 13119f177bb40251c69d693b6a942708 367 SMART SM00359 276 359 7.2E-23 T 10-03-2017 IPR002478 PUA domain GO:0003723 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 SUPERFAMILY SSF53633 6 256 1.13E-65 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS10465 13119f177bb40251c69d693b6a942708 367 Gene3D G3DSA:2.30.130.10 273 365 1.9E-26 T 10-03-2017 IPR015947 PUA-like domain RG49_RS10465 13119f177bb40251c69d693b6a942708 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 207 224 - T 10-03-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 PRINTS PR00474 Glutamate 5-kinase family signature 116 137 2.9E-57 T 10-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 PRINTS PR00474 Glutamate 5-kinase family signature 209 229 2.9E-57 T 10-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 PRINTS PR00474 Glutamate 5-kinase family signature 76 104 2.9E-57 T 10-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 PRINTS PR00474 Glutamate 5-kinase family signature 148 175 2.9E-57 T 10-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 PRINTS PR00474 Glutamate 5-kinase family signature 42 56 2.9E-57 T 10-03-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 Pfam PF00696 Amino acid kinase family 6 234 1.7E-44 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS10465 13119f177bb40251c69d693b6a942708 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 258 36.214 T 10-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 365 5.4E-157 T 10-03-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 RG49_RS10465 13119f177bb40251c69d693b6a942708 367 SUPERFAMILY SSF88697 276 365 1.1E-23 T 10-03-2017 IPR015947 PUA-like domain RG49_RS10465 13119f177bb40251c69d693b6a942708 367 Pfam PF01472 PUA domain 276 350 1.4E-22 T 10-03-2017 IPR002478 PUA domain GO:0003723 RG49_RS01850 8e9f6946e556506a4b25b02adb2d3e90 109 SUPERFAMILY SSF141488 28 107 3.53E-24 T 10-03-2017 IPR018660 C-type lysozyme, inhibitor RG49_RS01850 8e9f6946e556506a4b25b02adb2d3e90 109 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 35 96 2.8E-17 T 10-03-2017 IPR018660 C-type lysozyme, inhibitor RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 SUPERFAMILY SSF46785 10 121 9.9E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 SUPERFAMILY SSF53850 102 305 1.04E-30 T 10-03-2017 RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 1.4E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 1.4E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 1.4E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 Gene3D G3DSA:3.40.190.10 103 185 4.4E-18 T 10-03-2017 RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 Pfam PF03466 LysR substrate binding domain 101 304 1.5E-32 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 4.1E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 Gene3D G3DSA:3.40.190.10 186 272 9.4E-10 T 10-03-2017 RG49_RS03305 fc2a7101356ddd3241030d783952b9ba 307 Gene3D G3DSA:1.10.10.10 10 90 4.7E-25 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21995 2ada1d8c9a5eb60c0809f05c5353ff39 255 SUPERFAMILY SSF75217 1 247 4.71E-103 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS21995 2ada1d8c9a5eb60c0809f05c5353ff39 255 PIRSF PIRSF000386 1 253 6.4E-105 T 10-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 RG49_RS21995 2ada1d8c9a5eb60c0809f05c5353ff39 255 Gene3D G3DSA:1.10.1270.20 161 251 3.3E-38 T 10-03-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 RG49_RS21995 2ada1d8c9a5eb60c0809f05c5353ff39 255 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 3.5E-113 T 10-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 RG49_RS21995 2ada1d8c9a5eb60c0809f05c5353ff39 255 Gene3D G3DSA:3.40.1280.10 1 160 5.7E-68 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS21995 2ada1d8c9a5eb60c0809f05c5353ff39 255 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 2.6E-73 T 10-03-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 RG49_RS21995 2ada1d8c9a5eb60c0809f05c5353ff39 255 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 255 122.122 T 10-03-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 RG49_RS11220 7a19fc763018cea7a941ca7feb7122bf 220 Gene3D G3DSA:3.40.1050.10 1 216 2.7E-77 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS11220 7a19fc763018cea7a941ca7feb7122bf 220 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 10-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS11220 7a19fc763018cea7a941ca7feb7122bf 220 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 10-03-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS11220 7a19fc763018cea7a941ca7feb7122bf 220 SMART SM00947 30 192 1.3E-69 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS11220 7a19fc763018cea7a941ca7feb7122bf 220 Pfam PF00484 Carbonic anhydrase 38 187 2.9E-50 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS11220 7a19fc763018cea7a941ca7feb7122bf 220 SUPERFAMILY SSF53056 2 211 3.4E-74 T 10-03-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 Gene3D G3DSA:3.40.50.300 9 253 2.3E-81 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 SMART SM00382 42 225 5.2E-17 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 48 372 5.1E-169 T 10-03-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 SUPERFAMILY SSF50331 250 364 1.36E-7 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 Pfam PF00005 ABC transporter 35 174 3.1E-34 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 Pfam PF08402 TOBE domain 292 372 2.2E-8 T 10-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 SUPERFAMILY SSF52540 17 258 3.08E-88 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04980 8298de0c0cef9ebec11bfe5447380d15 378 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24900 1d4e208b42696b9d44faee8dfac7e953 405 SUPERFAMILY SSF53756 11 405 1.05E-26 T 10-03-2017 RG49_RS24900 1d4e208b42696b9d44faee8dfac7e953 405 Gene3D G3DSA:3.40.50.2000 295 357 6.8E-4 T 10-03-2017 RG49_RS24900 1d4e208b42696b9d44faee8dfac7e953 405 TIGRFAM TIGR04015 WcaC: colanic acid biosynthesis glycosyltransferase WcaC 1 405 1.1E-271 T 10-03-2017 IPR023916 Colanic acid biosynthesis, glycosyl transferase, WcaC RG49_RS24900 1d4e208b42696b9d44faee8dfac7e953 405 Pfam PF13439 Glycosyltransferase Family 4 13 223 3.9E-10 T 10-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 RG49_RS24900 1d4e208b42696b9d44faee8dfac7e953 405 Pfam PF00534 Glycosyl transferases group 1 292 349 9.1E-7 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 369 1.2E-81 T 10-03-2017 IPR020536 Thil, AANH domain GO:0004810 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 377 3.5E-147 T 10-03-2017 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 Pfam PF02926 THUMP domain 28 161 2.6E-29 T 10-03-2017 IPR004114 THUMP domain GO:0003723 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 383 482 1.5E-40 T 10-03-2017 IPR026340 Thiazole biosynthesis domain GO:0052837 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 Gene3D G3DSA:3.40.50.620 173 333 1.1E-37 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 Gene3D G3DSA:3.40.250.10 407 480 8.9E-8 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 SUPERFAMILY SSF143437 1 173 2.96E-51 T 10-03-2017 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 SMART SM00981 75 165 9.9E-27 T 10-03-2017 IPR004114 THUMP domain GO:0003723 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 SUPERFAMILY SSF52821 405 481 3.6E-9 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 482 232.463 T 10-03-2017 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 RG49_RS09015 40eefeb932a427e6f57410b53b69e3b2 482 SUPERFAMILY SSF52402 174 372 7.28E-42 T 10-03-2017 RG49_RS18755 3e5a1611818dc3e68ad57f45d999d7a6 282 Pfam PF00809 Pterin binding enzyme 18 257 6.1E-92 T 10-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS18755 3e5a1611818dc3e68ad57f45d999d7a6 282 Gene3D G3DSA:3.20.20.20 12 274 2.0E-111 T 10-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS18755 3e5a1611818dc3e68ad57f45d999d7a6 282 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 10-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS18755 3e5a1611818dc3e68ad57f45d999d7a6 282 SUPERFAMILY SSF51717 6 274 2.62E-106 T 10-03-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS18755 3e5a1611818dc3e68ad57f45d999d7a6 282 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 10-03-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 RG49_RS18755 3e5a1611818dc3e68ad57f45d999d7a6 282 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 17 271 1.8E-103 T 10-03-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 Gene3D G3DSA:3.30.70.20 73 159 1.7E-13 T 10-03-2017 RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 Pfam PF13187 4Fe-4S dicluster domain 37 82 1.2E-7 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 Pfam PF00037 4Fe-4S binding domain 136 157 4.9E-7 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 Gene3D G3DSA:3.30.70.20 36 72 1.6E-10 T 10-03-2017 RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 141 152 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 TIGRFAM TIGR00402 napF: ferredoxin-type protein NapF 7 157 7.5E-75 T 10-03-2017 IPR004496 Ferredoxin-type protein NapF GO:0005506|GO:0009055 RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 SUPERFAMILY SSF54862 33 158 5.44E-18 T 10-03-2017 RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 Pfam PF12800 4Fe-4S binding domain 101 118 0.6 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS24100 cad22991413e0146a109f188c8615ed5 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 37 48 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 Gene3D G3DSA:3.40.50.620 1 157 1.6E-57 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 1.7E-18 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 SUPERFAMILY SSF52374 3 156 4.29E-47 T 10-03-2017 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 37.122 T 10-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 8.4E-53 T 10-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 8.4E-53 T 10-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 8.4E-53 T 10-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 8.4E-53 T 10-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 8.4E-53 T 10-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 Pfam PF01467 Cytidylyltransferase-like 6 134 4.9E-23 T 10-03-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 3.8E-62 T 10-03-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 RG49_RS16230 8e1971e3a4b5e90c16262507a38f99e8 159 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 0.001 T 10-03-2017 RG49_RS20135 e06a2ca3a1c2c1f670648988e603c36a 326 Pfam PF00437 Type II/IV secretion system protein 74 259 3.7E-42 T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS20135 e06a2ca3a1c2c1f670648988e603c36a 326 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 190 204 - T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS20135 e06a2ca3a1c2c1f670648988e603c36a 326 SMART SM00382 119 271 4.1E-5 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS20135 e06a2ca3a1c2c1f670648988e603c36a 326 Gene3D G3DSA:3.40.50.300 97 324 3.0E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20135 e06a2ca3a1c2c1f670648988e603c36a 326 SUPERFAMILY SSF52540 4 324 3.64E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20135 e06a2ca3a1c2c1f670648988e603c36a 326 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 2 325 6.2E-141 T 10-03-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 RG49_RS16700 675678ed15c3e500584ca420074d8870 50 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 10 29 - T 10-03-2017 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 RG49_RS16700 675678ed15c3e500584ca420074d8870 50 PRINTS PR00281 Hok/Gef cell toxic protein family signature 5 23 4.7E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS16700 675678ed15c3e500584ca420074d8870 50 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 47 4.7E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS16700 675678ed15c3e500584ca420074d8870 50 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 1 46 3.0E-20 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS16700 675678ed15c3e500584ca420074d8870 50 Pfam PF01848 Hok/gef family 5 46 2.5E-22 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 191 3.4E-22 T 10-03-2017 IPR023214 HAD-like domain RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 SUPERFAMILY SSF56784 7 216 8.54E-49 T 10-03-2017 IPR023214 HAD-like domain RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 7.8E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 7.8E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 7.8E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 Gene3D G3DSA:1.10.150.240 20 82 1.1E-37 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 Gene3D G3DSA:3.40.50.1000 83 216 3.4E-37 T 10-03-2017 IPR023214 HAD-like domain RG49_RS01370 f7aa6c1b22de856efc1870b36b05897a 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 89 191 3.2E-11 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS02590 52ed9bd70ee7a8206fa3a397f5a745bf 293 SUPERFAMILY SSF53850 86 283 9.08E-37 T 10-03-2017 RG49_RS02590 52ed9bd70ee7a8206fa3a397f5a745bf 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.1E-17 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS02590 52ed9bd70ee7a8206fa3a397f5a745bf 293 Gene3D G3DSA:1.10.10.10 1 80 2.4E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02590 52ed9bd70ee7a8206fa3a397f5a745bf 293 Gene3D G3DSA:3.40.190.10 84 190 3.8E-22 T 10-03-2017 RG49_RS02590 52ed9bd70ee7a8206fa3a397f5a745bf 293 Gene3D G3DSA:3.40.190.10 191 256 9.2E-11 T 10-03-2017 RG49_RS02590 52ed9bd70ee7a8206fa3a397f5a745bf 293 Pfam PF03466 LysR substrate binding domain 85 282 2.0E-44 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS02590 52ed9bd70ee7a8206fa3a397f5a745bf 293 SUPERFAMILY SSF46785 1 109 3.65E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 SUPERFAMILY SSF46906 68 141 1.09E-25 T 10-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 4.1E-24 T 10-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 1.0E-16 T 10-03-2017 RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.571 T 10-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.2E-29 T 10-03-2017 IPR020784 Ribosomal protein L11, N-terminal RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 SMART SM00649 9 141 4.6E-84 T 10-03-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 3.2E-65 T 10-03-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 SUPERFAMILY SSF54747 3 73 5.49E-30 T 10-03-2017 IPR020784 Ribosomal protein L11, N-terminal RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 Gene3D G3DSA:3.30.1550.10 2 72 9.8E-38 T 10-03-2017 IPR020784 Ribosomal protein L11, N-terminal RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 Gene3D G3DSA:1.10.10.250 73 141 1.5E-30 T 10-03-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 RG49_RS14180 8db149aa24ca533fb58ad37447a8e174 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 10-03-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 Gene3D G3DSA:3.40.50.300 122 296 4.6E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 SUPERFAMILY SSF48295 363 466 3.66E-38 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 SUPERFAMILY SSF52540 133 343 2.22E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 SMART SM00382 164 366 4.3E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 425 444 1.7E-54 T 10-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 197 211 1.7E-54 T 10-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 263 290 1.7E-54 T 10-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 229 243 1.7E-54 T 10-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 165 185 1.7E-54 T 10-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 466 34.474 T 10-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 ProSitePatterns PS01008 DnaA protein signature. 425 444 - T 10-03-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 Pfam PF11638 DnaA N-terminal domain 4 64 1.4E-19 T 10-03-2017 IPR024633 DnaA N-terminal domain RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 Pfam PF00308 Bacterial dnaA protein 133 349 3.8E-99 T 10-03-2017 IPR013317 Chromosomal replication initiator protein DnaA RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 Gene3D G3DSA:1.10.1750.10 366 466 7.3E-43 T 10-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 SMART SM00760 375 444 6.1E-45 T 10-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 376 444 1.1E-32 T 10-03-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 Gene3D G3DSA:1.10.8.60 298 365 5.6E-30 T 10-03-2017 RG49_RS15715 d32b2a2387fb39205c9d044690deb228 467 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 465 9.2E-188 T 10-03-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 RG49_RS10260 738960c2b664b6e7429bc0734f3c7112 56 ProDom PD027295 GP38 FLUMU BACTERIOPHAGE MU-LIKE ECS4978 SB12 PHAGE ORF10 PROPHAGE 1 54 4.0E-24 T 10-03-2017 IPR024400 Protein of unknown function DUF2635 RG49_RS10260 738960c2b664b6e7429bc0734f3c7112 56 Pfam PF10948 Protein of unknown function (DUF2635) 3 47 1.1E-17 T 10-03-2017 IPR024400 Protein of unknown function DUF2635 RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 Gene3D G3DSA:1.10.3710.10 348 444 2.2E-34 T 10-03-2017 RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 Gene3D G3DSA:1.10.8.60 154 228 1.6E-8 T 10-03-2017 RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 Pfam PF12002 MgsA AAA+ ATPase C terminal 268 434 3.1E-64 T 10-03-2017 IPR021886 MgsA AAA+ ATPase C-terminal RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 SUPERFAMILY SSF48019 252 434 6.23E-71 T 10-03-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 Pfam PF16193 AAA C-terminal domain 188 267 5.5E-22 T 10-03-2017 IPR032423 AAA ATPase, C-terminal domain RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 SUPERFAMILY SSF52540 6 234 1.53E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 Gene3D G3DSA:3.40.50.300 11 153 1.0E-33 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 SMART SM00382 49 165 2.6E-18 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 Gene3D G3DSA:1.20.272.10 249 347 3.1E-42 T 10-03-2017 RG49_RS06275 1b8f312befa2a16b4cd39723018054e6 447 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 159 4.7E-17 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS07040 6d77f6ea6d1b0442df5f049eec76867b 160 Pfam PF08719 Domain of unknown function (DUF1768) 19 156 9.5E-38 T 10-03-2017 IPR012816 NADAR RG49_RS07040 6d77f6ea6d1b0442df5f049eec76867b 160 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 17 156 1.7E-50 T 10-03-2017 IPR012816 NADAR RG49_RS07040 6d77f6ea6d1b0442df5f049eec76867b 160 SUPERFAMILY SSF143990 4 157 1.22E-58 T 10-03-2017 RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 Gene3D G3DSA:3.30.300.20 194 294 2.7E-40 T 10-03-2017 IPR015946 K homology domain-like, alpha/beta RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 Pfam PF07650 KH domain 209 285 2.0E-19 T 10-03-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 SUPERFAMILY SSF52540 11 205 6.79E-44 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 SUPERFAMILY SSF54814 182 297 1.96E-40 T 10-03-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 280 1.0E-120 T 10-03-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 170 1.3E-41 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 Hamap MF_00367 GTPase Era [era]. 6 297 35.38 T 10-03-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 Gene3D G3DSA:3.40.50.300 10 193 2.0E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22215 adcd2c234c40a28b9de3dc5ebd7053b3 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 5.5E-24 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS00605 a3cb1bd5ac6e95d6f876387cf18b336b 200 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 9 184 1.1E-45 T 10-03-2017 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family RG49_RS00605 a3cb1bd5ac6e95d6f876387cf18b336b 200 SUPERFAMILY SSF54001 9 185 3.43E-34 T 10-03-2017 RG49_RS00605 a3cb1bd5ac6e95d6f876387cf18b336b 200 Gene3D G3DSA:2.30.30.330 7 188 1.6E-45 T 10-03-2017 RG49_RS16375 02dcd79bfa3a280c3447f8ae51a2d301 157 Gene3D G3DSA:3.40.1280.10 1 154 6.1E-71 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS16375 02dcd79bfa3a280c3447f8ae51a2d301 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 152 1.5E-75 T 10-03-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 RG49_RS16375 02dcd79bfa3a280c3447f8ae51a2d301 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 34.464 T 10-03-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 RG49_RS16375 02dcd79bfa3a280c3447f8ae51a2d301 157 SUPERFAMILY SSF75217 1 152 3.66E-46 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS16375 02dcd79bfa3a280c3447f8ae51a2d301 157 Pfam PF00588 SpoU rRNA Methylase family 2 142 5.2E-34 T 10-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 RG49_RS16375 02dcd79bfa3a280c3447f8ae51a2d301 157 PIRSF PIRSF029256 1 154 2.9E-71 T 10-03-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 RG49_RS00795 ac6550df35d76a4f981336f112386fd3 232 SMART SM00945 5 119 6.6E-60 T 10-03-2017 IPR016103 ProQ/FinO domain RG49_RS00795 ac6550df35d76a4f981336f112386fd3 232 Gene3D G3DSA:1.10.1710.10 4 118 3.3E-36 T 10-03-2017 IPR016103 ProQ/FinO domain RG49_RS00795 ac6550df35d76a4f981336f112386fd3 232 Hamap MF_00749 RNA chaperone ProQ [proQ]. 3 231 30.419 T 10-03-2017 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 RG49_RS00795 ac6550df35d76a4f981336f112386fd3 232 SUPERFAMILY SSF48657 5 119 5.23E-40 T 10-03-2017 IPR016103 ProQ/FinO domain RG49_RS00795 ac6550df35d76a4f981336f112386fd3 232 Pfam PF04352 ProQ/FINO family 8 115 5.0E-42 T 10-03-2017 IPR016103 ProQ/FinO domain RG49_RS09210 33221920300f1b251518b225a4291ac6 371 Gene3D G3DSA:3.30.70.270 212 369 1.9E-46 T 10-03-2017 RG49_RS09210 33221920300f1b251518b225a4291ac6 371 Pfam PF05230 MASE2 domain 40 128 2.2E-28 T 10-03-2017 IPR007894 MASE2 RG49_RS09210 33221920300f1b251518b225a4291ac6 371 SMART SM00267 199 370 1.0E-66 T 10-03-2017 IPR000160 GGDEF domain RG49_RS09210 33221920300f1b251518b225a4291ac6 371 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 206 370 5.1E-66 T 10-03-2017 IPR000160 GGDEF domain RG49_RS09210 33221920300f1b251518b225a4291ac6 371 SUPERFAMILY SSF55073 215 368 4.71E-44 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS09210 33221920300f1b251518b225a4291ac6 371 Pfam PF00990 Diguanylate cyclase, GGDEF domain 211 366 4.5E-47 T 10-03-2017 IPR000160 GGDEF domain RG49_RS17490 fc45ab32822cf6d6aa81bfa278b69369 438 Pfam PF02447 GntP family permease 1 437 3.2E-188 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS17490 fc45ab32822cf6d6aa81bfa278b69369 438 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 438 7.4E-204 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS17490 fc45ab32822cf6d6aa81bfa278b69369 438 PIRSF PIRSF002746 1 438 5.0E-160 T 10-03-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 RG49_RS09990 901982f5aacb75ec35554f5c995398cc 93 Gene3D G3DSA:1.10.10.10 11 70 8.7E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09990 901982f5aacb75ec35554f5c995398cc 93 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 52 2.6E-14 T 10-03-2017 IPR010093 SinI-like, DNA-binding domain GO:0003677 RG49_RS09990 901982f5aacb75ec35554f5c995398cc 93 SUPERFAMILY SSF46955 9 57 1.43E-5 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS09990 901982f5aacb75ec35554f5c995398cc 93 Pfam PF12728 Helix-turn-helix domain 9 56 5.0E-14 T 10-03-2017 RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 SMART SM00062 26 246 5.7E-74 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 SMART SM00079 26 245 1.3E-7 T 10-03-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 48 61 - T 10-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 Gene3D G3DSA:3.40.190.10 24 102 2.8E-48 T 10-03-2017 RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 Gene3D G3DSA:3.40.190.10 207 246 2.8E-48 T 10-03-2017 RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 Gene3D G3DSA:3.40.190.10 103 206 8.8E-33 T 10-03-2017 RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 SUPERFAMILY SSF53850 7 245 8.25E-75 T 10-03-2017 RG49_RS06965 91e1fc09c4c0571f784e7272bf3d625a 248 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 244 1.1E-70 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS19825 6172b58c5c135df201c48fa84ad539cc 499 Pfam PF01384 Phosphate transporter family 206 488 2.1E-44 T 10-03-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 RG49_RS19825 6172b58c5c135df201c48fa84ad539cc 499 Pfam PF01384 Phosphate transporter family 30 182 2.7E-35 T 10-03-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 346 3.4E-9 T 10-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 SUPERFAMILY SSF56672 1 234 1.51E-94 T 10-03-2017 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 Pfam PF00817 impB/mucB/samB family 7 154 2.8E-49 T 10-03-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 Pfam PF11798 IMS family HHH motif 166 197 5.7E-8 T 10-03-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 Gene3D G3DSA:1.10.150.20 165 237 6.1E-26 T 10-03-2017 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 Gene3D G3DSA:3.30.1490.100 238 349 2.4E-44 T 10-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 Gene3D G3DSA:3.30.70.270 66 164 8.4E-37 T 10-03-2017 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 Hamap MF_01113 DNA polymerase IV [dinB]. 1 349 37.245 T 10-03-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 RG49_RS10520 aadc10fda1d5a3dde4488aa54bf32245 351 SUPERFAMILY SSF100879 241 349 5.69E-27 T 10-03-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 338 359 2.0E-55 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 150 169 2.0E-55 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 2.0E-55 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 2.0E-55 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 2.0E-55 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 2.0E-55 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 SUPERFAMILY SSF53697 5 548 1.33E-229 T 10-03-2017 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 Gene3D G3DSA:1.10.1390.10 511 548 6.8E-23 T 10-03-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 Gene3D G3DSA:3.40.50.10490 99 290 1.1E-92 T 10-03-2017 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 Gene3D G3DSA:3.40.50.10490 8 98 6.7E-149 T 10-03-2017 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 Gene3D G3DSA:3.40.50.10490 293 510 6.7E-149 T 10-03-2017 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 Pfam PF00342 Phosphoglucose isomerase 52 541 8.8E-259 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 524 43.344 T 10-03-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 10-03-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS13935 b27dd7db316ffeb6a91464fc033cd01c 549 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 10-03-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS07525 2c11111f5c692e0943811d78a4052950 244 Pfam PF03746 LamB/YcsF family 3 235 1.7E-94 T 10-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF RG49_RS07525 2c11111f5c692e0943811d78a4052950 244 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 240 43.226 T 10-03-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF RG49_RS07525 2c11111f5c692e0943811d78a4052950 244 SUPERFAMILY SSF88713 1 242 2.22E-92 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS03870 716e68a97fbca16b35ec7ff2a5d22076 316 SUPERFAMILY SSF52402 4 153 7.03E-26 T 10-03-2017 RG49_RS03870 716e68a97fbca16b35ec7ff2a5d22076 316 Gene3D G3DSA:3.40.50.620 143 303 2.2E-31 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS03870 716e68a97fbca16b35ec7ff2a5d22076 316 Pfam PF00582 Universal stress protein family 174 300 5.7E-15 T 10-03-2017 IPR006016 UspA GO:0006950 RG49_RS03870 716e68a97fbca16b35ec7ff2a5d22076 316 Pfam PF00582 Universal stress protein family 3 146 1.5E-18 T 10-03-2017 IPR006016 UspA GO:0006950 RG49_RS03870 716e68a97fbca16b35ec7ff2a5d22076 316 Gene3D G3DSA:3.40.50.620 1 142 1.7E-22 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS03870 716e68a97fbca16b35ec7ff2a5d22076 316 SUPERFAMILY SSF52402 155 307 5.86E-25 T 10-03-2017 RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 Gene3D G3DSA:3.30.70.1450 303 374 6.8E-7 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 Pfam PF02080 TrkA-C domain 229 281 1.4E-8 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 Pfam PF02080 TrkA-C domain 304 371 5.7E-9 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 Pfam PF06826 Predicted Permease Membrane Region 17 182 2.0E-40 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 Pfam PF06826 Predicted Permease Membrane Region 385 555 6.2E-43 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 SUPERFAMILY SSF116726 291 374 2.09E-11 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 Gene3D G3DSA:3.30.70.1450 229 282 2.0E-8 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 Hamap MF_01015 Putative transport protein YbjL [ybjL]. 1 557 57.611 T 10-03-2017 IPR023017 Transport protein YbjL, putative RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 21 169 4.7E-38 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 390 541 4.6E-44 T 10-03-2017 IPR006512 YidE/YbjL duplication RG49_RS06535 9a2c4228f5bfbb5f6538863abfd0e1ab 561 SUPERFAMILY SSF116726 227 282 1.7E-10 T 10-03-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 RG49_RS03155 02f42b4dbeb72169c67d10f922543823 172 SUPERFAMILY SSF55729 3 165 2.92E-35 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS03155 02f42b4dbeb72169c67d10f922543823 172 Gene3D G3DSA:3.40.630.30 1 166 2.5E-42 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS03155 02f42b4dbeb72169c67d10f922543823 172 Pfam PF13420 Acetyltransferase (GNAT) domain 3 154 6.8E-19 T 10-03-2017 RG49_RS09470 685e109994c1166c5b0021c666f95f19 483 SUPERFAMILY SSF103378 13 482 1.7E-161 T 10-03-2017 IPR005656 MmgE/PrpD GO:0016829 RG49_RS09470 685e109994c1166c5b0021c666f95f19 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 1.3E-280 T 10-03-2017 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 RG49_RS09470 685e109994c1166c5b0021c666f95f19 483 Gene3D G3DSA:3.30.1330.120 287 426 2.8E-64 T 10-03-2017 RG49_RS09470 685e109994c1166c5b0021c666f95f19 483 Pfam PF03972 MmgE/PrpD family 18 463 4.2E-159 T 10-03-2017 IPR005656 MmgE/PrpD GO:0016829 RG49_RS05915 d1ce4d7b32591cf9d320610439123b43 720 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 11 709 0.0 T 10-03-2017 IPR010019 Integral membrane protein, YccS RG49_RS05915 d1ce4d7b32591cf9d320610439123b43 720 Pfam PF12805 FUSC-like inner membrane protein yccS 69 348 2.4E-110 T 10-03-2017 IPR032692 Integral membrane protein YccS, N-terminal RG49_RS05915 d1ce4d7b32591cf9d320610439123b43 720 Pfam PF13515 Fusaric acid resistance protein-like 406 528 1.9E-25 T 10-03-2017 RG49_RS05915 d1ce4d7b32591cf9d320610439123b43 720 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 11 708 0.0 T 10-03-2017 IPR010020 Integral membrane protein, YccS/YhfK RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 10-03-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 SUPERFAMILY SSF69075 317 417 2.48E-27 T 10-03-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 Gene3D G3DSA:3.40.50.720 184 358 1.1E-38 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 418 30.895 T 10-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 416 5.2E-24 T 10-03-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 306 5.3E-49 T 10-03-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 PIRSF PIRSF000445 1 418 4.6E-155 T 10-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 2.0E-49 T 10-03-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 SUPERFAMILY SSF69742 1 158 3.27E-47 T 10-03-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 418 1.1E-171 T 10-03-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 RG49_RS04580 3cf93802fe5816e9d12b939a19da52dd 418 SUPERFAMILY SSF51735 162 315 1.64E-34 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21765 4f563011ab0db0a71851097347585757 149 SMART SM00749 28 91 3.6E-9 T 10-03-2017 IPR014004 Transport-associated and nodulation domain, bacteria RG49_RS21765 4f563011ab0db0a71851097347585757 149 SUPERFAMILY SSF54106 97 147 4.84E-8 T 10-03-2017 IPR018392 LysM domain RG49_RS21765 4f563011ab0db0a71851097347585757 149 Pfam PF01476 LysM domain 99 147 1.3E-12 T 10-03-2017 IPR018392 LysM domain RG49_RS21765 4f563011ab0db0a71851097347585757 149 Pfam PF04972 BON domain 24 89 7.1E-10 T 10-03-2017 IPR007055 BON domain RG49_RS21765 4f563011ab0db0a71851097347585757 149 SMART SM00257 98 147 3.4E-14 T 10-03-2017 IPR018392 LysM domain RG49_RS21765 4f563011ab0db0a71851097347585757 149 Gene3D G3DSA:3.10.350.10 97 148 4.0E-12 T 10-03-2017 IPR018392 LysM domain RG49_RS05345 5af841e045682f26b4c0ce5b97d1f90f 84 ProDom PD060858 YCEP CYTOPLASMIC STY1199 ESCHERICHIA COLI SIMILAR ECS1438 1 84 8.0E-45 T 10-03-2017 IPR025730 Biofilm regulator BssS RG49_RS05345 5af841e045682f26b4c0ce5b97d1f90f 84 Pfam PF13991 BssS protein family 11 80 2.1E-32 T 10-03-2017 IPR025730 Biofilm regulator BssS RG49_RS14370 d9a3b3f2a1c4ea763303ebf8b1d91fd5 106 SUPERFAMILY SSF52794 3 101 7.15E-35 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS14370 d9a3b3f2a1c4ea763303ebf8b1d91fd5 106 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 89 4.0E-41 T 10-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 RG49_RS14370 d9a3b3f2a1c4ea763303ebf8b1d91fd5 106 Gene3D G3DSA:3.40.50.2300 2 101 6.6E-41 T 10-03-2017 RG49_RS14370 d9a3b3f2a1c4ea763303ebf8b1d91fd5 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 95 1.1E-20 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS12415 b7f699208de5c64f3c0c3f23b600fe86 176 SUPERFAMILY SSF49401 26 176 4.03E-35 T 10-03-2017 IPR008966 Adhesion domain RG49_RS12415 b7f699208de5c64f3c0c3f23b600fe86 176 Gene3D G3DSA:2.60.40.1090 26 176 3.8E-42 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12415 b7f699208de5c64f3c0c3f23b600fe86 176 Pfam PF00419 Fimbrial protein 28 176 3.5E-21 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS19555 ad81bda048b47ada29af16196e44b9c9 271 Gene3D G3DSA:3.40.830.10 6 271 5.1E-100 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS19555 ad81bda048b47ada29af16196e44b9c9 271 SUPERFAMILY SSF53213 14 271 9.02E-91 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS19555 ad81bda048b47ada29af16196e44b9c9 271 PIRSF PIRSF006157 10 271 5.4E-94 T 10-03-2017 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 RG49_RS19555 ad81bda048b47ada29af16196e44b9c9 271 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 18 266 4.9E-24 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS17195 bf988953eba496afa2b4fe4ebd3ae75c 195 Gene3D G3DSA:3.90.470.20 31 99 2.8E-13 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS17195 bf988953eba496afa2b4fe4ebd3ae75c 195 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 88 172 2.0E-9 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS17195 bf988953eba496afa2b4fe4ebd3ae75c 195 Gene3D G3DSA:3.90.470.20 100 145 4.2E-15 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS17195 bf988953eba496afa2b4fe4ebd3ae75c 195 SUPERFAMILY SSF56214 29 79 5.75E-10 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS17195 bf988953eba496afa2b4fe4ebd3ae75c 195 SUPERFAMILY SSF56214 87 180 8.63E-17 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS00105 9a9419020a3cc6ec4acf291097ff67f7 156 Gene3D G3DSA:3.40.960.10 21 154 3.9E-51 T 10-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 RG49_RS00105 9a9419020a3cc6ec4acf291097ff67f7 156 SUPERFAMILY SSF52980 2 153 1.5E-54 T 10-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 RG49_RS00105 9a9419020a3cc6ec4acf291097ff67f7 156 Pfam PF03852 DNA mismatch endonuclease Vsr 2 74 1.1E-39 T 10-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 RG49_RS00105 9a9419020a3cc6ec4acf291097ff67f7 156 PIRSF PIRSF018267 1 150 1.0E-51 T 10-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 RG49_RS00105 9a9419020a3cc6ec4acf291097ff67f7 156 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 118 7.1E-55 T 10-03-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 RG49_RS18050 88dcf3c63abf6783733af222cd11271c 123 SUPERFAMILY SSF50193 2 122 2.35E-51 T 10-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 RG49_RS18050 88dcf3c63abf6783733af222cd11271c 123 Gene3D G3DSA:2.40.150.20 1 123 5.2E-56 T 10-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 RG49_RS18050 88dcf3c63abf6783733af222cd11271c 123 Pfam PF00238 Ribosomal protein L14p/L23e 1 123 8.5E-55 T 10-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 RG49_RS18050 88dcf3c63abf6783733af222cd11271c 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 10-03-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18050 88dcf3c63abf6783733af222cd11271c 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 4.5E-60 T 10-03-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 RG49_RS18050 88dcf3c63abf6783733af222cd11271c 123 SMART SM01374 1 123 3.7E-86 T 10-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 RG49_RS18050 88dcf3c63abf6783733af222cd11271c 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 28.628 T 10-03-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 Gene3D G3DSA:4.10.520.10 2 93 3.4E-36 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 97 4.6E-55 T 10-03-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 3.1E-17 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 3.1E-17 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 3.1E-17 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 Pfam PF00216 Bacterial DNA-binding protein 3 91 2.7E-30 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 SUPERFAMILY SSF47729 3 93 1.16E-31 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 SMART SM00411 3 92 1.2E-43 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 31.158 T 10-03-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 RG49_RS01460 59ec5d46b9f3ed5fc9297c10221bdeba 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 10-03-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 RG49_RS12840 6325425a92a89626d48ce49677acdf37 206 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 117 203 3.5E-28 T 10-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 RG49_RS12840 6325425a92a89626d48ce49677acdf37 206 Gene3D G3DSA:1.10.287.460 2 88 1.6E-25 T 10-03-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 RG49_RS12840 6325425a92a89626d48ce49677acdf37 206 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 3 108 7.0E-23 T 10-03-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 RG49_RS12840 6325425a92a89626d48ce49677acdf37 206 Gene3D G3DSA:3.10.50.40 89 205 4.3E-51 T 10-03-2017 RG49_RS12840 6325425a92a89626d48ce49677acdf37 206 SUPERFAMILY SSF54534 8 205 2.75E-56 T 10-03-2017 RG49_RS05635 6fd762a726bed2f229328b8b53567025 382 Hamap MF_01699 Pyrimidine monooxygenase RutA [rutA]. 20 379 70.785 T 10-03-2017 IPR019914 Pyrimidine monooxygenase RutA GO:0004497|GO:0006212|GO:0055114 KEGG: 00240+1.14.99.46 RG49_RS05635 6fd762a726bed2f229328b8b53567025 382 Pfam PF00296 Luciferase-like monooxygenase 20 339 5.1E-70 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS05635 6fd762a726bed2f229328b8b53567025 382 Gene3D G3DSA:3.20.20.30 20 371 5.5E-88 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS05635 6fd762a726bed2f229328b8b53567025 382 SUPERFAMILY SSF51679 20 371 8.24E-79 T 10-03-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 RG49_RS05635 6fd762a726bed2f229328b8b53567025 382 TIGRFAM TIGR03612 RutA: pyrimidine utilization protein A 20 373 1.8E-219 T 10-03-2017 IPR019914 Pyrimidine monooxygenase RutA GO:0004497|GO:0006212|GO:0055114 KEGG: 00240+1.14.99.46 RG49_RS14855 753fb57e92ecb164d2d6f391a4063990 168 Pfam PF04220 Der GTPase activator (YihI) 13 165 1.6E-54 T 10-03-2017 IPR007336 Der GTPase activator RG49_RS14855 753fb57e92ecb164d2d6f391a4063990 168 Hamap MF_01058 Der GTPase-activating protein YihI [yihI]. 1 168 16.885 T 10-03-2017 IPR007336 Der GTPase activator RG49_RS03015 a4d8e837edefc90c36de53a2b884e396 462 SUPERFAMILY SSF103473 17 457 4.58E-37 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS03015 a4d8e837edefc90c36de53a2b884e396 462 Gene3D G3DSA:1.20.1250.20 254 455 1.7E-10 T 10-03-2017 RG49_RS03015 a4d8e837edefc90c36de53a2b884e396 462 Gene3D G3DSA:1.20.1250.20 29 229 9.4E-16 T 10-03-2017 RG49_RS03015 a4d8e837edefc90c36de53a2b884e396 462 TIGRFAM TIGR00886 2A0108: nitrite transporter 34 415 2.8E-102 T 10-03-2017 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 RG49_RS03015 a4d8e837edefc90c36de53a2b884e396 462 Pfam PF07690 Major Facilitator Superfamily 43 419 4.4E-9 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS15645 2dd390efbb297fdf3787ac4199229a20 445 PIRSF PIRSF005353 5 444 5.9E-177 T 10-03-2017 IPR026033 Purine permease PbuG-like RG49_RS15645 2dd390efbb297fdf3787ac4199229a20 445 Pfam PF00860 Permease family 31 404 2.4E-42 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS14990 da7f412fdc1ccffb025e39e30b20e8f0 260 PIRSF PIRSF005902 1 260 2.1E-77 T 10-03-2017 IPR001130 TatD family GO:0016788 RG49_RS14990 da7f412fdc1ccffb025e39e30b20e8f0 260 SUPERFAMILY SSF51556 1 258 7.38E-86 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS14990 da7f412fdc1ccffb025e39e30b20e8f0 260 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 123 133 - T 10-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 RG49_RS14990 da7f412fdc1ccffb025e39e30b20e8f0 260 Hamap MF_00901 3'-5' ssDNA/RNA exonuclease TatD [tatD]. 1 259 65.72 T 10-03-2017 IPR024918 3'-5' ssDNA/RNA exonuclease TatD GO:0008408 RG49_RS14990 da7f412fdc1ccffb025e39e30b20e8f0 260 Gene3D G3DSA:3.20.20.140 1 258 1.9E-87 T 10-03-2017 RG49_RS14990 da7f412fdc1ccffb025e39e30b20e8f0 260 Pfam PF01026 TatD related DNase 2 256 2.0E-70 T 10-03-2017 IPR001130 TatD family GO:0016788 RG49_RS14990 da7f412fdc1ccffb025e39e30b20e8f0 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 10-03-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 ProSitePatterns PS00883 Nickel-dependent hydrogenases b-type cytochrome subunit signature 2. 181 198 - T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 ProSitePatterns PS00882 Nickel-dependent hydrogenases b-type cytochrome subunit signature 1. 19 36 - T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 TIGRFAM TIGR02125 CytB-hydogenase: Ni/Fe-hydrogenase, b-type cytochrome subunit 12 225 7.9E-79 T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 Gene3D G3DSA:1.20.950.20 11 226 4.9E-27 T 10-03-2017 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 Pfam PF01292 Prokaryotic cytochrome b561 14 220 3.8E-36 T 10-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 SUPERFAMILY SSF81342 9 226 4.71E-40 T 10-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 54 78 4.0E-47 T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 132 151 4.0E-47 T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 16 39 4.0E-47 T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 212 225 4.0E-47 T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS05840 ab1cbcd0eedf4d4c97cc1238f46674f4 235 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 181 203 4.0E-47 T 10-03-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 SUPERFAMILY SSF143243 9 194 1.57E-47 T 10-03-2017 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 36 152 3.8E-25 T 10-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 Pfam PF00374 Nickel-dependent hydrogenase 218 286 2.4E-13 T 10-03-2017 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 296 464 1.2E-34 T 10-03-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 466 537 5.0E-11 T 10-03-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 216 227 - T 10-03-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 141 5.0E-25 T 10-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 Gene3D G3DSA:1.10.645.10 166 536 5.3E-88 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21475 3eac3c2263398f6d02c5588500b228f2 569 SUPERFAMILY SSF56762 193 537 4.45E-109 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21025 05793d33afddf98c3a809ef19fa95319 140 SUPERFAMILY SSF102546 1 139 1.96E-38 T 10-03-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 RG49_RS21025 05793d33afddf98c3a809ef19fa95319 140 Hamap MF_01662 L-fucose mutarotase [fucU]. 1 140 48.785 T 10-03-2017 IPR023751 L-fucose mutarotase GO:0016854|GO:0042354|GO:0042806 RG49_RS21025 05793d33afddf98c3a809ef19fa95319 140 Gene3D G3DSA:3.40.1650.10 1 139 8.4E-50 T 10-03-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 RG49_RS21025 05793d33afddf98c3a809ef19fa95319 140 Pfam PF05025 RbsD / FucU transport protein family 4 139 9.6E-35 T 10-03-2017 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 240 4.0E-89 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 249 435 1.6E-32 T 10-03-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 TIGRFAM TIGR01312 XylB: xylulokinase 3 477 3.6E-197 T 10-03-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 347 367 - T 10-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 PIRSF PIRSF000538 1 484 1.6E-138 T 10-03-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 SUPERFAMILY SSF53067 2 242 9.72E-74 T 10-03-2017 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 Gene3D G3DSA:3.30.420.40 243 482 4.5E-55 T 10-03-2017 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 Gene3D G3DSA:3.30.420.40 1 240 1.1E-69 T 10-03-2017 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 126 138 - T 10-03-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 RG49_RS16655 4f9001d2fe0e53e02c47bc828b59a67f 484 SUPERFAMILY SSF53067 242 482 3.61E-63 T 10-03-2017 RG49_RS02935 ce57e563d2a484e580c09854d14c2e25 45 ProDom PD049510 RIBOSOMAL S22 30S RIBONUCLEOPROTEIN SUBUNIT D RIBOSOME- SEQUENCING DIRECT ASSOCIATED 1 45 2.0E-19 T 10-03-2017 IPR012607 Ribosomal protein S22 GO:0003735|GO:0005840|GO:0006412 RG49_RS02935 ce57e563d2a484e580c09854d14c2e25 45 Pfam PF08136 30S ribosomal protein subunit S22 family 1 44 1.8E-31 T 10-03-2017 IPR012607 Ribosomal protein S22 GO:0003735|GO:0005840|GO:0006412 RG49_RS21785 d83ef5229638d820c14eec3e18d115ea 482 SUPERFAMILY SSF53720 6 481 1.96E-178 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS21785 d83ef5229638d820c14eec3e18d115ea 482 Pfam PF00171 Aldehyde dehydrogenase family 19 477 4.4E-177 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS21785 d83ef5229638d820c14eec3e18d115ea 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS21785 d83ef5229638d820c14eec3e18d115ea 482 Gene3D G3DSA:3.40.605.10 10 268 2.2E-107 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS21785 d83ef5229638d820c14eec3e18d115ea 482 Gene3D G3DSA:3.40.309.10 269 453 5.4E-71 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS21785 d83ef5229638d820c14eec3e18d115ea 482 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 476 4.1E-243 T 10-03-2017 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 RG49_RS21785 d83ef5229638d820c14eec3e18d115ea 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS10115 1947b48afb01b9ef2690cc08824c74ca 79 SUPERFAMILY SSF54786 10 74 1.88E-30 T 10-03-2017 RG49_RS10115 1947b48afb01b9ef2690cc08824c74ca 79 Pfam PF06006 Bacterial protein of unknown function (DUF905) 6 74 5.6E-41 T 10-03-2017 IPR009253 Protein of unknown function DUF905 RG49_RS10115 1947b48afb01b9ef2690cc08824c74ca 79 ProDom PD028015 PLASMID YKFF YDEA R0111 YPJI YPMT1.60C C4569 AEC70 PSLT067 YFJA 7 66 3.0E-29 T 10-03-2017 IPR009253 Protein of unknown function DUF905 RG49_RS10115 1947b48afb01b9ef2690cc08824c74ca 79 Gene3D G3DSA:3.30.160.130 2 73 5.6E-38 T 10-03-2017 RG49_RS01275 40238e118d2cf8c8336ac5ef71cb2ea7 322 PIRSF PIRSF017020 1 322 2.6E-118 T 10-03-2017 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 RG49_RS01275 40238e118d2cf8c8336ac5ef71cb2ea7 322 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 45 320 1.7E-72 T 10-03-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 RG49_RS01275 40238e118d2cf8c8336ac5ef71cb2ea7 322 TIGRFAM TIGR03242 arg_catab_astE: succinylglutamate desuccinylase 3 318 4.2E-145 T 10-03-2017 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 RG49_RS01275 40238e118d2cf8c8336ac5ef71cb2ea7 322 SUPERFAMILY SSF53187 1 319 2.88E-92 T 10-03-2017 RG49_RS01275 40238e118d2cf8c8336ac5ef71cb2ea7 322 Hamap MF_00767 Succinylglutamate desuccinylase [astE]. 1 322 152.422 T 10-03-2017 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 RG49_RS01275 40238e118d2cf8c8336ac5ef71cb2ea7 322 Gene3D G3DSA:3.40.630.10 45 235 4.3E-14 T 10-03-2017 RG49_RS16110 d09805aa0ef41910cd26ac0a0cc948d6 460 SUPERFAMILY SSF103473 13 426 6.8E-30 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS16110 d09805aa0ef41910cd26ac0a0cc948d6 460 Pfam PF13347 MFS/sugar transport protein 13 431 2.5E-101 T 10-03-2017 RG49_RS16110 d09805aa0ef41910cd26ac0a0cc948d6 460 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 444 1.8E-155 T 10-03-2017 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 RG49_RS16110 d09805aa0ef41910cd26ac0a0cc948d6 460 Gene3D G3DSA:1.20.1250.20 23 208 1.8E-9 T 10-03-2017 RG49_RS16110 d09805aa0ef41910cd26ac0a0cc948d6 460 Gene3D G3DSA:1.20.1250.20 231 421 4.5E-5 T 10-03-2017 RG49_RS16110 d09805aa0ef41910cd26ac0a0cc948d6 460 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 62 87 - T 10-03-2017 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 TIGRFAM TIGR01068 thioredoxin: thioredoxin 45 141 7.9E-32 T 10-03-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 SUPERFAMILY SSF52833 27 143 6.26E-37 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 ProSitePatterns PS00194 Thioredoxin family active site. 61 79 - T 10-03-2017 IPR017937 Thioredoxin, conserved site GO:0045454 RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 PRINTS PR00421 Thioredoxin family signature 68 77 4.0E-9 T 10-03-2017 RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 PRINTS PR00421 Thioredoxin family signature 108 119 4.0E-9 T 10-03-2017 RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 PRINTS PR00421 Thioredoxin family signature 60 68 4.0E-9 T 10-03-2017 RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 Gene3D G3DSA:3.40.30.10 35 143 7.0E-34 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS10040 f10a04eb162283f987bf277f850db51e 146 Pfam PF00085 Thioredoxin 42 140 1.5E-28 T 10-03-2017 IPR013766 Thioredoxin domain GO:0045454 RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 10-03-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 Gene3D G3DSA:3.40.640.10 45 315 2.9E-108 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 Pfam PF00155 Aminotransferase class I and II 28 392 4.1E-96 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 SUPERFAMILY SSF53383 1 396 5.23E-118 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 7.3E-40 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 7.3E-40 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 7.3E-40 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS06090 378fb80b3f4935dbe3a309d2cca355f1 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 7.3E-40 T 10-03-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 RG49_RS15625 cf25bdeb432fb5432f7962022fb5d0ab 240 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 14 220 3.5E-16 T 10-03-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 RG49_RS15625 cf25bdeb432fb5432f7962022fb5d0ab 240 Gene3D G3DSA:3.40.50.1360 1 237 1.3E-59 T 10-03-2017 RG49_RS15625 cf25bdeb432fb5432f7962022fb5d0ab 240 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 113 131 - T 10-03-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 RG49_RS15625 cf25bdeb432fb5432f7962022fb5d0ab 240 SUPERFAMILY SSF100950 1 237 2.15E-56 T 10-03-2017 RG49_RS06775 65646c01bd712f5483197e9bb4866a7b 178 SUPERFAMILY SSF48498 98 175 2.13E-7 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS06775 65646c01bd712f5483197e9bb4866a7b 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.8E-8 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS06775 65646c01bd712f5483197e9bb4866a7b 178 SUPERFAMILY SSF46689 2 81 5.13E-14 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS06775 65646c01bd712f5483197e9bb4866a7b 178 Gene3D G3DSA:1.10.357.10 8 176 1.2E-32 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS05885 4b892b3a20ad0325ba607d03b9f71716 137 Gene3D G3DSA:3.40.50.720 3 135 2.4E-49 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05885 4b892b3a20ad0325ba607d03b9f71716 137 SMART SM00881 9 104 1.5E-26 T 10-03-2017 IPR003781 CoA-binding GO:0048037 RG49_RS05885 4b892b3a20ad0325ba607d03b9f71716 137 SUPERFAMILY SSF51735 4 135 7.44E-44 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS05885 4b892b3a20ad0325ba607d03b9f71716 137 Pfam PF13380 CoA binding domain 15 130 3.6E-39 T 10-03-2017 IPR003781 CoA-binding GO:0048037 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 Gene3D G3DSA:3.40.50.720 2 246 1.8E-69 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 2.4E-52 T 10-03-2017 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 SUPERFAMILY SSF51735 1 246 8.06E-67 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 8 247 2.3E-108 T 10-03-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 74 91 1.6E-67 T 10-03-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 94 114 1.6E-67 T 10-03-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 159 182 1.6E-67 T 10-03-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 12 29 1.6E-67 T 10-03-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 198 217 1.6E-67 T 10-03-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 224 243 1.6E-67 T 10-03-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.7E-7 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.7E-7 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.7E-7 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS08150 216c34eb7acfa7f37d7865ed513aaf0b 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 177 4.2E-4 T 10-03-2017 RG49_RS07830 bc349f7f8df2734ffd8537ed0b956f81 246 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 132 3.4E-15 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS07830 bc349f7f8df2734ffd8537ed0b956f81 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 238 4.3E-27 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07830 bc349f7f8df2734ffd8537ed0b956f81 246 SUPERFAMILY SSF161098 24 223 1.1E-37 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07830 bc349f7f8df2734ffd8537ed0b956f81 246 Gene3D G3DSA:1.10.3720.10 23 238 7.9E-43 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 10-03-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 41 56 - T 10-03-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 SUPERFAMILY SSF55594 4 90 3.66E-24 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 4 84 2.6E-22 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 PRINTS PR00107 Phosphocarrier protein signature 14 30 3.3E-8 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 PRINTS PR00107 Phosphocarrier protein signature 55 72 3.3E-8 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 PRINTS PR00107 Phosphocarrier protein signature 40 55 3.3E-8 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 Gene3D G3DSA:3.30.1340.10 3 89 1.6E-26 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS18610 f957fc3f45621e04f1c53152aea9a048 90 Pfam PF00381 PTS HPr component phosphorylation site 4 84 2.0E-22 T 10-03-2017 IPR000032 Phosphocarrier protein HPr-like RG49_RS17380 3f062636bed0cf06fa22e81645b5893b 231 SUPERFAMILY SSF51182 1 231 1.73E-80 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS17380 3f062636bed0cf06fa22e81645b5893b 231 Pfam PF02678 Pirin 7 119 9.8E-38 T 10-03-2017 IPR003829 Pirin, N-terminal domain RG49_RS17380 3f062636bed0cf06fa22e81645b5893b 231 PIRSF PIRSF006232 1 230 4.0E-58 T 10-03-2017 IPR012093 Pirin RG49_RS17380 3f062636bed0cf06fa22e81645b5893b 231 Gene3D G3DSA:2.60.120.10 4 230 2.0E-72 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS19530 22384031d28e470141f123b8f993dcd1 183 Pfam PF00419 Fimbrial protein 31 182 8.9E-19 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS19530 22384031d28e470141f123b8f993dcd1 183 SUPERFAMILY SSF49401 30 183 8.45E-32 T 10-03-2017 IPR008966 Adhesion domain RG49_RS19530 22384031d28e470141f123b8f993dcd1 183 Gene3D G3DSA:2.60.40.1090 29 183 8.5E-36 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS16260 11369b91dbae38e8c7c6eea7a7b4121e 359 Pfam PF13439 Glycosyltransferase Family 4 13 166 2.3E-12 T 10-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 RG49_RS16260 11369b91dbae38e8c7c6eea7a7b4121e 359 Pfam PF00534 Glycosyl transferases group 1 175 323 6.1E-23 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS16260 11369b91dbae38e8c7c6eea7a7b4121e 359 SUPERFAMILY SSF53756 2 322 1.53E-50 T 10-03-2017 RG49_RS16260 11369b91dbae38e8c7c6eea7a7b4121e 359 Gene3D G3DSA:3.40.50.2000 173 321 7.2E-16 T 10-03-2017 RG49_RS20525 e7f7fb8fc2de0bf7d7dceacb242dfcb9 256 Gene3D G3DSA:3.40.1190.10 14 59 5.1E-6 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS20525 e7f7fb8fc2de0bf7d7dceacb242dfcb9 256 SUPERFAMILY SSF53623 14 123 4.49E-8 T 10-03-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 RG49_RS20525 e7f7fb8fc2de0bf7d7dceacb242dfcb9 256 TIGRFAM TIGR03172 TIGR03172: putative selenium-dependent hydroxylase accessory protein YqeC 22 247 6.4E-90 T 10-03-2017 IPR017587 Putative selenium-dependent hydroxylase accessory protein YqeC RG49_RS09400 409d085d544a96c694d1b7076277c4c9 315 Gene3D G3DSA:3.30.450.40 119 292 9.3E-28 T 10-03-2017 IPR029016 GAF domain-like RG49_RS09400 409d085d544a96c694d1b7076277c4c9 315 Gene3D G3DSA:1.10.10.10 43 118 1.0E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09400 409d085d544a96c694d1b7076277c4c9 315 Pfam PF09339 IclR helix-turn-helix domain 53 103 5.2E-15 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS09400 409d085d544a96c694d1b7076277c4c9 315 SUPERFAMILY SSF46785 51 121 8.2E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09400 409d085d544a96c694d1b7076277c4c9 315 SMART SM00346 50 140 2.3E-32 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS09400 409d085d544a96c694d1b7076277c4c9 315 Pfam PF01614 Bacterial transcriptional regulator 173 295 3.9E-12 T 10-03-2017 IPR014757 Transcription regulator IclR, C-terminal RG49_RS09400 409d085d544a96c694d1b7076277c4c9 315 SUPERFAMILY SSF55781 123 295 1.14E-25 T 10-03-2017 IPR029016 GAF domain-like RG49_RS18200 20b18bc21df64dddb5161c4fc8c49677 85 Pfam PF07369 Protein of unknown function (DUF1488) 5 84 3.9E-31 T 10-03-2017 IPR009962 Protein of unknown function DUF1488 RG49_RS18200 20b18bc21df64dddb5161c4fc8c49677 85 Gene3D G3DSA:3.30.160.140 2 84 3.3E-39 T 10-03-2017 IPR009962 Protein of unknown function DUF1488 RG49_RS18200 20b18bc21df64dddb5161c4fc8c49677 85 SUPERFAMILY SSF160272 2 84 1.57E-31 T 10-03-2017 IPR009962 Protein of unknown function DUF1488 RG49_RS23195 b26138351d78f48b9db353bd3f76767e 418 Hamap MF_01115 Putative ion-transport protein YfeO [yfeO]. 1 411 51.006 T 10-03-2017 IPR022969 Chloride channel YfeO RG49_RS23195 b26138351d78f48b9db353bd3f76767e 418 Pfam PF00654 Voltage gated chloride channel 93 391 1.3E-18 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS23195 b26138351d78f48b9db353bd3f76767e 418 PRINTS PR00762 Chloride channel signature 103 122 4.9E-7 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS23195 b26138351d78f48b9db353bd3f76767e 418 PRINTS PR00762 Chloride channel signature 320 340 4.9E-7 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS23195 b26138351d78f48b9db353bd3f76767e 418 PRINTS PR00762 Chloride channel signature 153 172 4.9E-7 T 10-03-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 RG49_RS23195 b26138351d78f48b9db353bd3f76767e 418 Gene3D G3DSA:1.10.3080.10 12 361 6.9E-19 T 10-03-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 RG49_RS23195 b26138351d78f48b9db353bd3f76767e 418 SUPERFAMILY SSF81340 9 398 2.62E-44 T 10-03-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 RG49_RS03700 bf3bed8e9d3cfd5fbcc95472093dcf3c 141 Gene3D G3DSA:1.10.3600.10 1 122 1.3E-50 T 10-03-2017 IPR009364 Putative bacterial toxin ydaT RG49_RS03700 bf3bed8e9d3cfd5fbcc95472093dcf3c 141 Pfam PF06254 Putative bacterial toxin ydaT 48 101 3.7E-10 T 10-03-2017 IPR009364 Putative bacterial toxin ydaT RG49_RS23590 74cb2e4ad26a58ae7d690fcd8db285bc 506 Pfam PF03606 C4-dicarboxylate anaerobic carrier 15 501 2.2E-164 T 10-03-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 RG49_RS22770 8d841e0474b30257f6ea30847a91b30a 344 Hamap MF_00924 Outer membrane protein assembly factor BamC [bamC]. 9 343 39.586 T 10-03-2017 IPR014524 Outer membrane protein assembly factor BamC RG49_RS22770 8d841e0474b30257f6ea30847a91b30a 344 PIRSF PIRSF026343 9 344 1.2E-150 T 10-03-2017 IPR014524 Outer membrane protein assembly factor BamC RG49_RS22770 8d841e0474b30257f6ea30847a91b30a 344 Pfam PF06804 NlpB/DapX lipoprotein 41 342 6.5E-112 T 10-03-2017 IPR010653 NlpB/DapX lipoprotein RG49_RS11000 26945a7f97dfc64de2925cea9fd84b75 270 Gene3D G3DSA:3.60.21.10 48 218 1.6E-18 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS11000 26945a7f97dfc64de2925cea9fd84b75 270 Pfam PF00149 Calcineurin-like phosphoesterase 49 211 1.5E-10 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS11000 26945a7f97dfc64de2925cea9fd84b75 270 SUPERFAMILY SSF56300 49 237 1.04E-26 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS23435 d1aae2b452c937d9f0a6166ced75b9d7 274 Hamap MF_01623 Penicillin-insensitive murein endopeptidase [mepA]. 1 274 70.416 T 10-03-2017 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 RG49_RS23435 d1aae2b452c937d9f0a6166ced75b9d7 274 Pfam PF03411 Penicillin-insensitive murein endopeptidase 36 270 4.1E-94 T 10-03-2017 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 RG49_RS23435 d1aae2b452c937d9f0a6166ced75b9d7 274 PIRSF PIRSF018455 1 274 1.1E-120 T 10-03-2017 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 RG49_RS23435 d1aae2b452c937d9f0a6166ced75b9d7 274 SUPERFAMILY SSF55166 21 272 1.02E-102 T 10-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 RG49_RS23435 d1aae2b452c937d9f0a6166ced75b9d7 274 Gene3D G3DSA:3.30.1380.10 21 272 7.6E-107 T 10-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 4.1E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 4.1E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 4.1E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 4.1E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 4.1E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 4.1E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 Gene3D G3DSA:3.40.50.720 14 259 1.5E-78 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 4.0E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 4.0E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 4.0E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 258 2.8E-55 T 10-03-2017 RG49_RS21185 af896292b9c2d733eb7d2017220e5a18 261 SUPERFAMILY SSF51735 17 260 1.01E-75 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Gene3D G3DSA:3.30.1360.120 1 121 2.3E-42 T 10-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Pfam PF12631 MnmE helical domain 123 451 5.7E-61 T 10-03-2017 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Gene3D G3DSA:1.20.120.430 248 271 9.3E-60 T 10-03-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Gene3D G3DSA:1.20.120.430 384 454 9.3E-60 T 10-03-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Gene3D G3DSA:1.20.120.430 122 182 9.3E-60 T 10-03-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 370 6.4E-24 T 10-03-2017 IPR005225 Small GTP-binding protein domain GO:0005525 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 120 4.4E-34 T 10-03-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 SUPERFAMILY SSF116878 379 454 2.48E-51 T 10-03-2017 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 SUPERFAMILY SSF116878 121 220 2.48E-51 T 10-03-2017 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 454 33.378 T 10-03-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Gene3D G3DSA:3.40.50.300 286 376 1.3E-7 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 454 4.8E-101 T 10-03-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 SUPERFAMILY SSF52540 72 152 2.66E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 SUPERFAMILY SSF52540 188 372 2.66E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Pfam PF01926 50S ribosome-binding GTPase 218 336 7.7E-25 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS15685 ca47321ff276a44d263a8eea8fbb42a1 454 Gene3D G3DSA:3.40.50.300 201 247 3.1E-8 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13040 215d629d08578afa7c3679e091d4fd50 334 SUPERFAMILY SSF117892 196 233 1.31E-7 T 10-03-2017 IPR001107 Band 7 domain RG49_RS13040 215d629d08578afa7c3679e091d4fd50 334 SMART SM00244 18 227 1.5E-47 T 10-03-2017 IPR001107 Band 7 domain RG49_RS13040 215d629d08578afa7c3679e091d4fd50 334 PIRSF PIRSF005651 1 334 9.5E-111 T 10-03-2017 IPR010200 HflC GO:0016021|GO:0052547 RG49_RS13040 215d629d08578afa7c3679e091d4fd50 334 Pfam PF01145 SPFH domain / Band 7 family 22 243 1.3E-34 T 10-03-2017 IPR001107 Band 7 domain RG49_RS13040 215d629d08578afa7c3679e091d4fd50 334 SUPERFAMILY SSF117892 56 157 1.06E-16 T 10-03-2017 IPR001107 Band 7 domain RG49_RS13040 215d629d08578afa7c3679e091d4fd50 334 TIGRFAM TIGR01932 hflC: HflC protein 1 327 8.0E-150 T 10-03-2017 IPR010200 HflC GO:0016021|GO:0052547 RG49_RS18430 1e53a06f337176a1b4bd9e96a8ebbd36 87 SUPERFAMILY SSF159871 3 87 2.75E-27 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS18430 1e53a06f337176a1b4bd9e96a8ebbd36 87 Pfam PF07338 Protein of unknown function (DUF1471) 35 87 2.8E-22 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS18430 1e53a06f337176a1b4bd9e96a8ebbd36 87 Gene3D G3DSA:3.30.1660.10 18 87 1.5E-31 T 10-03-2017 IPR025543 Dodecin-like RG49_RS19255 c06e38f52e8a68b67ff3930022960dc2 183 Pfam PF10688 Bacterial inner membrane protein 5 163 3.8E-57 T 10-03-2017 IPR019629 Uncharacterised protein family HI1736/YgjV RG49_RS19255 c06e38f52e8a68b67ff3930022960dc2 183 PIRSF PIRSF011443 1 182 1.6E-70 T 10-03-2017 IPR026267 Inner membrane protein YgjV RG49_RS24640 fdc6fc0c80a9ef25222dfa3d221b16a9 826 Pfam PF00577 Outer membrane usher protein 177 743 8.1E-189 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS24640 fdc6fc0c80a9ef25222dfa3d221b16a9 826 SUPERFAMILY SSF141729 49 153 9.42E-27 T 10-03-2017 RG49_RS24640 fdc6fc0c80a9ef25222dfa3d221b16a9 826 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 289 299 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS24640 fdc6fc0c80a9ef25222dfa3d221b16a9 826 Pfam PF13954 PapC N-terminal domain 26 161 5.8E-32 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS24640 fdc6fc0c80a9ef25222dfa3d221b16a9 826 Pfam PF13953 PapC C-terminal domain 753 813 8.5E-9 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS03400 41fd30115411c6ee7659000ff0af28dc 316 Pfam PF08223 PaaX-like protein C-terminal domain 104 273 5.0E-55 T 10-03-2017 IPR013225 PaaX-like, C-terminal RG49_RS03400 41fd30115411c6ee7659000ff0af28dc 316 PIRSF PIRSF020623 1 305 8.7E-134 T 10-03-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 RG49_RS03400 41fd30115411c6ee7659000ff0af28dc 316 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 21 302 4.4E-123 T 10-03-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 RG49_RS03400 41fd30115411c6ee7659000ff0af28dc 316 Pfam PF07848 PaaX-like protein 19 87 3.8E-29 T 10-03-2017 IPR012906 PaaX-like, N-terminal RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 338 1.2E-72 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 1.6E-15 T 10-03-2017 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.6E-15 T 10-03-2017 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 1.6E-15 T 10-03-2017 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.6E-15 T 10-03-2017 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 Gene3D G3DSA:3.50.50.60 6 183 4.2E-25 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.4E-8 T 10-03-2017 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 2.4E-8 T 10-03-2017 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.4E-8 T 10-03-2017 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 Gene3D G3DSA:3.50.50.60 184 353 4.4E-31 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS05095 f2108371cb53148312dca0a82f35964a 434 SUPERFAMILY SSF51905 6 345 2.54E-34 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS19745 ea52332cb2bb7fff6c16aee08c7f9baf 164 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 1 163 5.0E-81 T 10-03-2017 IPR020761 Uncharacterised protein family UPF0114, bacteria RG49_RS19745 ea52332cb2bb7fff6c16aee08c7f9baf 164 Pfam PF03350 Uncharacterized protein family, UPF0114 9 125 1.3E-35 T 10-03-2017 IPR005134 Uncharacterised protein family UPF0114 RG49_RS19745 ea52332cb2bb7fff6c16aee08c7f9baf 164 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 164 92.813 T 10-03-2017 IPR020765 Uncharacterised protein family UPF0114, gammaproteobacteria GO:0005886 RG49_RS07965 87c2edf23054567453efff5ea0bb05f9 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 88 1.7E-14 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS07965 87c2edf23054567453efff5ea0bb05f9 317 Gene3D G3DSA:3.40.190.10 197 283 4.0E-11 T 10-03-2017 RG49_RS07965 87c2edf23054567453efff5ea0bb05f9 317 SUPERFAMILY SSF53850 116 317 1.39E-20 T 10-03-2017 RG49_RS07965 87c2edf23054567453efff5ea0bb05f9 317 SUPERFAMILY SSF46785 26 106 3.54E-17 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07965 87c2edf23054567453efff5ea0bb05f9 317 Gene3D G3DSA:3.40.190.10 116 196 9.7E-11 T 10-03-2017 RG49_RS07965 87c2edf23054567453efff5ea0bb05f9 317 Pfam PF03466 LysR substrate binding domain 116 316 3.8E-17 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS07965 87c2edf23054567453efff5ea0bb05f9 317 Gene3D G3DSA:1.10.10.10 25 106 7.3E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 4.7E-14 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 SMART SM00895 97 220 1.8E-17 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 Gene3D G3DSA:1.10.10.10 5 70 3.8E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 SUPERFAMILY SSF46785 4 72 3.98E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 Gene3D G3DSA:1.20.120.530 93 227 7.0E-26 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 SUPERFAMILY SSF48008 98 227 8.89E-25 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 Pfam PF07729 FCD domain 99 218 3.4E-25 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 SMART SM00345 9 68 1.3E-10 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 3.9E-5 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS15750 763f7017b7dc4d72eba1fdff27ead134 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 3.9E-5 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS20650 a25acaa7ae28723ffb2f21839a6f63a5 243 Pfam PF01312 FlhB HrpN YscU SpaS Family 3 239 3.8E-61 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS20650 a25acaa7ae28723ffb2f21839a6f63a5 243 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 5 27 1.5E-23 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS20650 a25acaa7ae28723ffb2f21839a6f63a5 243 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 216 233 1.5E-23 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS20650 a25acaa7ae28723ffb2f21839a6f63a5 243 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 196 214 1.5E-23 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS20650 a25acaa7ae28723ffb2f21839a6f63a5 243 Gene3D G3DSA:3.40.1690.10 205 239 3.2E-10 T 10-03-2017 IPR029025 Type III secretion system substrate exporter, C-terminal RG49_RS05610 e4c94b3a8fd7418becca2af71351fc02 502 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 437 4.0E-133 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS05610 e4c94b3a8fd7418becca2af71351fc02 502 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 10-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS05610 e4c94b3a8fd7418becca2af71351fc02 502 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 419 439 - T 10-03-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS05610 e4c94b3a8fd7418becca2af71351fc02 502 Pfam PF00474 Sodium:solute symporter family 35 437 1.3E-147 T 10-03-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS05610 e4c94b3a8fd7418becca2af71351fc02 502 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 6 490 6.8E-234 T 10-03-2017 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SMART SM00564 114 146 1.3E-4 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SMART SM00564 65 96 4.1E-5 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SMART SM00564 155 186 5.3E-5 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SMART SM00564 200 231 66.0 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SMART SM00564 289 320 310.0 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SMART SM00564 251 282 7.7E-5 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SMART SM00564 329 361 1.6E-4 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 Gene3D G3DSA:2.140.10.10 3 390 7.1E-78 T 10-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 2 392 40.769 T 10-03-2017 IPR017687 Outer membrane protein assembly factor BamB RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 8 390 1.0E-132 T 10-03-2017 IPR017687 Outer membrane protein assembly factor BamB RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 Pfam PF13360 PQQ-like domain 78 319 9.9E-53 T 10-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat RG49_RS22510 11e83d0da51cd4cfe60ac1337b9b4a23 392 SUPERFAMILY SSF50998 25 382 2.01E-79 T 10-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily RG49_RS18980 142622366e4a80266460912b00e79f63 377 PIRSF PIRSF038994 1 376 2.5E-115 T 10-03-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 RG49_RS18980 142622366e4a80266460912b00e79f63 377 Gene3D G3DSA:2.30.40.10 327 373 3.7E-11 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS18980 142622366e4a80266460912b00e79f63 377 Gene3D G3DSA:3.20.20.140 59 326 2.3E-101 T 10-03-2017 RG49_RS18980 142622366e4a80266460912b00e79f63 377 SUPERFAMILY SSF51338 346 374 8.24E-9 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS18980 142622366e4a80266460912b00e79f63 377 SUPERFAMILY SSF51338 2 49 8.24E-9 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS18980 142622366e4a80266460912b00e79f63 377 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 372 6.8E-87 T 10-03-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 RG49_RS18980 142622366e4a80266460912b00e79f63 377 Pfam PF01979 Amidohydrolase family 47 373 1.0E-16 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS18980 142622366e4a80266460912b00e79f63 377 Gene3D G3DSA:2.30.40.10 3 58 5.9E-5 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS18980 142622366e4a80266460912b00e79f63 377 SUPERFAMILY SSF51556 51 346 4.08E-95 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS01645 64078aac8b5dc42b35ab8b4722c81d13 334 Gene3D G3DSA:3.10.350.10 40 86 1.3E-7 T 10-03-2017 IPR018392 LysM domain RG49_RS01645 64078aac8b5dc42b35ab8b4722c81d13 334 SMART SM00257 41 85 4.0E-8 T 10-03-2017 IPR018392 LysM domain RG49_RS01645 64078aac8b5dc42b35ab8b4722c81d13 334 Gene3D G3DSA:2.40.440.10 90 234 5.9E-35 T 10-03-2017 RG49_RS01645 64078aac8b5dc42b35ab8b4722c81d13 334 SUPERFAMILY SSF141523 94 232 8.89E-30 T 10-03-2017 RG49_RS01645 64078aac8b5dc42b35ab8b4722c81d13 334 Pfam PF03734 L,D-transpeptidase catalytic domain 97 232 4.0E-21 T 10-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 RG49_RS01645 64078aac8b5dc42b35ab8b4722c81d13 334 Pfam PF01476 LysM domain 42 85 1.7E-8 T 10-03-2017 IPR018392 LysM domain RG49_RS20045 84b00af581981befae53586c755e7623 235 Pfam PF04474 Protein of unknown function (DUF554) 3 227 1.7E-68 T 10-03-2017 IPR007563 Protein of unknown function DUF554 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 SMART SM00411 1 90 3.1E-43 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 10-03-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 Gene3D G3DSA:4.10.520.10 1 90 3.1E-37 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 SUPERFAMILY SSF47729 1 90 8.54E-33 T 10-03-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.9E-33 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.0E-19 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.0E-19 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS14085 4939a1cdd4b26c7d9053b02c16db7e41 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.0E-19 T 10-03-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 RG49_RS07105 b138ca230bc137682d8cb2006075bdfc 150 Gene3D G3DSA:3.90.1170.40 4 150 2.1E-57 T 10-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS07105 b138ca230bc137682d8cb2006075bdfc 150 SUPERFAMILY SSF54690 6 150 9.68E-55 T 10-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS07105 b138ca230bc137682d8cb2006075bdfc 150 Pfam PF02391 MoaE protein 11 121 8.1E-37 T 10-03-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 RG49_RS01560 2430db0e67ee8cbbeb6c0d725090a453 252 ProSitePatterns PS01028 Dehydroquinase class I active site. 114 144 - T 10-03-2017 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS01560 2430db0e67ee8cbbeb6c0d725090a453 252 SUPERFAMILY SSF51569 1 251 1.1E-82 T 10-03-2017 RG49_RS01560 2430db0e67ee8cbbeb6c0d725090a453 252 Gene3D G3DSA:3.20.20.70 1 251 4.3E-92 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS01560 2430db0e67ee8cbbeb6c0d725090a453 252 Pfam PF01487 Type I 3-dehydroquinase 20 246 5.8E-70 T 10-03-2017 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS01560 2430db0e67ee8cbbeb6c0d725090a453 252 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 17 245 1.0E-87 T 10-03-2017 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS01560 2430db0e67ee8cbbeb6c0d725090a453 252 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 17 249 41.568 T 10-03-2017 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 RG49_RS02975 961b815ebde82a7027bb8be22f93dd7d 293 SUPERFAMILY SSF103481 191 291 3.92E-6 T 10-03-2017 RG49_RS02975 961b815ebde82a7027bb8be22f93dd7d 293 Pfam PF00892 EamA-like transporter family 6 137 1.1E-7 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS02975 961b815ebde82a7027bb8be22f93dd7d 293 Pfam PF00892 EamA-like transporter family 158 285 3.1E-8 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS02975 961b815ebde82a7027bb8be22f93dd7d 293 SUPERFAMILY SSF103481 48 140 7.85E-6 T 10-03-2017 RG49_RS24770 333881755834af746a09dcb8f81fd6b2 110 Gene3D G3DSA:3.30.160.160 3 49 5.0E-23 T 10-03-2017 IPR010879 Domain of unknown function DUF1508 RG49_RS24770 333881755834af746a09dcb8f81fd6b2 110 Gene3D G3DSA:3.30.160.160 55 100 2.1E-21 T 10-03-2017 IPR010879 Domain of unknown function DUF1508 RG49_RS24770 333881755834af746a09dcb8f81fd6b2 110 SUPERFAMILY SSF160113 61 108 3.53E-16 T 10-03-2017 IPR010879 Domain of unknown function DUF1508 RG49_RS24770 333881755834af746a09dcb8f81fd6b2 110 Pfam PF07411 Domain of unknown function (DUF1508) 61 108 3.2E-21 T 10-03-2017 IPR010879 Domain of unknown function DUF1508 RG49_RS24770 333881755834af746a09dcb8f81fd6b2 110 Pfam PF07411 Domain of unknown function (DUF1508) 11 57 4.4E-22 T 10-03-2017 IPR010879 Domain of unknown function DUF1508 RG49_RS24770 333881755834af746a09dcb8f81fd6b2 110 SUPERFAMILY SSF160113 1 57 9.94E-20 T 10-03-2017 IPR010879 Domain of unknown function DUF1508 RG49_RS05485 33ddad67eb91298cd65bde74be7d1547 184 Pfam PF02613 Nitrate reductase delta subunit 36 147 4.5E-15 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS05485 33ddad67eb91298cd65bde74be7d1547 184 PIRSF PIRSF004690 1 184 1.2E-58 T 10-03-2017 IPR026269 Tat proofreading chaperone DmsD-type RG49_RS05485 33ddad67eb91298cd65bde74be7d1547 184 SUPERFAMILY SSF89155 2 180 3.79E-45 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS05485 33ddad67eb91298cd65bde74be7d1547 184 Gene3D G3DSA:1.10.3480.10 1 181 9.9E-52 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS17360 babaa1d5cd288ff95cffb8a2fb6b66d6 164 Gene3D G3DSA:3.40.1580.10 3 160 7.6E-5 T 10-03-2017 IPR018958 SMI1/KNR4-like domain RG49_RS17360 babaa1d5cd288ff95cffb8a2fb6b66d6 164 SUPERFAMILY SSF160631 61 161 9.81E-6 T 10-03-2017 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SUPERFAMILY SSF52540 416 618 9.78E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SMART SM00958 228 358 5.0E-84 T 10-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Pfam PF07517 SecA DEAD-like domain 7 402 9.1E-132 T 10-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 19.957 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SUPERFAMILY SSF81886 620 840 2.35E-85 T 10-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SUPERFAMILY SSF81886 877 889 2.35E-85 T 10-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Gene3D G3DSA:1.10.3060.10 648 831 6.9E-60 T 10-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SUPERFAMILY SSF81767 227 368 4.58E-44 T 10-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 817 0.0 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Pfam PF07516 SecA Wing and Scaffold domain 617 830 7.7E-69 T 10-03-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Gene3D G3DSA:3.90.1440.10 230 368 7.3E-47 T 10-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Gene3D G3DSA:3.40.50.300 417 619 1.5E-90 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Gene3D G3DSA:3.40.50.300 369 416 2.9E-125 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Gene3D G3DSA:3.40.50.300 2 228 2.9E-125 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Pfam PF02810 SEC-C motif 881 899 9.9E-11 T 10-03-2017 IPR004027 SEC-C motif RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SMART SM00957 6 402 0.0 T 10-03-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SUPERFAMILY SSF52540 368 415 9.24E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 SUPERFAMILY SSF52540 5 228 9.24E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 PRINTS PR00906 SecA protein signature 170 190 7.5E-74 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 PRINTS PR00906 SecA protein signature 376 393 7.5E-74 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 PRINTS PR00906 SecA protein signature 63 87 7.5E-74 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 PRINTS PR00906 SecA protein signature 101 115 7.5E-74 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 PRINTS PR00906 SecA protein signature 339 361 7.5E-74 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 PRINTS PR00906 SecA protein signature 413 426 7.5E-74 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 PRINTS PR00906 SecA protein signature 117 127 7.5E-74 T 10-03-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 ProSitePatterns PS01312 SecA family signature. 500 515 - T 10-03-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 RG49_RS11365 1baad8fe077050f7097e1f3d00a93ace 901 Pfam PF01043 SecA preprotein cross-linking domain 232 358 1.7E-39 T 10-03-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 RG49_RS04440 5ccfe3545b85ce0ab83db92902a6a7ca 152 SUPERFAMILY SSF103642 132 151 4.41E-8 T 10-03-2017 RG49_RS04440 5ccfe3545b85ce0ab83db92902a6a7ca 152 SUPERFAMILY SSF54427 25 129 3.8E-37 T 10-03-2017 IPR032710 NTF2-like domain RG49_RS04440 5ccfe3545b85ce0ab83db92902a6a7ca 152 Pfam PF02810 SEC-C motif 134 152 6.2E-11 T 10-03-2017 IPR004027 SEC-C motif RG49_RS04440 5ccfe3545b85ce0ab83db92902a6a7ca 152 Pfam PF02810 SEC-C motif 3 19 1.2E-4 T 10-03-2017 IPR004027 SEC-C motif RG49_RS04440 5ccfe3545b85ce0ab83db92902a6a7ca 152 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 1 128 30.412 T 10-03-2017 IPR023006 Uncharacterised protein family UPF0225 RG49_RS04440 5ccfe3545b85ce0ab83db92902a6a7ca 152 Gene3D G3DSA:3.10.450.50 2 152 1.3E-56 T 10-03-2017 IPR032710 NTF2-like domain RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 PRINTS PR00112 Acylphosphatase signature 5 20 3.0E-8 T 10-03-2017 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 PRINTS PR00112 Acylphosphatase signature 26 51 3.0E-8 T 10-03-2017 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 PRINTS PR00112 Acylphosphatase signature 61 81 3.0E-8 T 10-03-2017 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 10-03-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 10-03-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 SUPERFAMILY SSF54975 2 92 7.41E-31 T 10-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 Hamap MF_01450 Acylphosphatase [yccX]. 2 92 32.13 T 10-03-2017 IPR028627 Acylphosphatase, bacteria GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 Gene3D G3DSA:3.30.70.100 5 92 6.1E-33 T 10-03-2017 RG49_RS05870 cd83cab5cc9df4753f5e7611f601ecab 92 Pfam PF00708 Acylphosphatase 8 92 9.4E-27 T 10-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS12275 f105ad9536e407bf4e7de52529047253 113 Pfam PF08845 Toxin SymE, type I toxin-antitoxin system 20 71 8.0E-20 T 10-03-2017 IPR014944 Toxin SymE-like GO:0003723|GO:0005737|GO:0016070|GO:0016788 RG49_RS12275 f105ad9536e407bf4e7de52529047253 113 Hamap MF_01193 Endoribonuclease SymE [symE]. 1 110 43.754 T 10-03-2017 IPR020883 Type I toxin-antitoxin system, SymE toxin GO:0003723|GO:0004521|GO:0005737|GO:0016070 RG49_RS07840 38cdb0dacca0e9d5add18020d599e6ed 241 Pfam PF00005 ABC transporter 17 165 4.8E-34 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS07840 38cdb0dacca0e9d5add18020d599e6ed 241 SMART SM00382 26 213 9.6E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS07840 38cdb0dacca0e9d5add18020d599e6ed 241 PIRSF PIRSF039085 1 241 1.4E-105 T 10-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 RG49_RS07840 38cdb0dacca0e9d5add18020d599e6ed 241 Gene3D G3DSA:3.40.50.300 1 236 1.3E-81 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07840 38cdb0dacca0e9d5add18020d599e6ed 241 SUPERFAMILY SSF52540 1 235 1.52E-77 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07840 38cdb0dacca0e9d5add18020d599e6ed 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 SUPERFAMILY SSF55048 128 197 2.62E-18 T 10-03-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 1.7E-138 T 10-03-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 SUPERFAMILY SSF52151 4 122 2.38E-81 T 10-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 SUPERFAMILY SSF52151 190 308 2.38E-81 T 10-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 Pfam PF00698 Acyl transferase domain 6 283 2.8E-38 T 10-03-2017 IPR014043 Acyl transferase RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 PIRSF PIRSF000446 1 309 6.7E-148 T 10-03-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 Gene3D G3DSA:3.40.366.10 3 122 1.4E-71 T 10-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 Gene3D G3DSA:3.40.366.10 197 298 1.4E-71 T 10-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 308 1.4E-39 T 10-03-2017 IPR020801 Polyketide synthase, acyl transferase domain RG49_RS05185 75d678b45ba19441726218d751c1e7a9 309 Gene3D G3DSA:3.30.70.250 125 196 1.3E-32 T 10-03-2017 RG49_RS24005 d01941948f66f5161fac7a8827d20ba1 220 Gene3D G3DSA:3.40.1080.10 3 215 4.2E-78 T 10-03-2017 RG49_RS24005 d01941948f66f5161fac7a8827d20ba1 220 SUPERFAMILY SSF100950 2 217 1.54E-76 T 10-03-2017 RG49_RS24005 d01941948f66f5161fac7a8827d20ba1 220 SMART SM00882 5 216 5.1E-72 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS24005 d01941948f66f5161fac7a8827d20ba1 220 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 10-03-2017 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 RG49_RS24005 d01941948f66f5161fac7a8827d20ba1 220 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 6 217 2.5E-65 T 10-03-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 RG49_RS24005 d01941948f66f5161fac7a8827d20ba1 220 Pfam PF01144 Coenzyme A transferase 6 215 7.5E-71 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 SUPERFAMILY SSF47203 226 381 4.19E-50 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 2.5E-45 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 Gene3D G3DSA:2.40.110.10 121 217 9.6E-28 T 10-03-2017 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 1.3E-22 T 10-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 10-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 SUPERFAMILY SSF56645 1 227 2.36E-51 T 10-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 10-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 107 3.2E-17 T 10-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 Gene3D G3DSA:1.20.140.10 218 382 8.7E-59 T 10-03-2017 RG49_RS01550 f4fbd7821c38d46764fc40e1be629d2d 383 Gene3D G3DSA:1.10.540.10 1 109 5.5E-21 T 10-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 RG49_RS01240 05f3752d12267af8cdcca90e672ff82c 236 Pfam PF09335 SNARE associated Golgi protein 63 179 5.9E-27 T 10-03-2017 IPR032816 SNARE associated Golgi protein RG49_RS19100 ca56b70754b7c70da7559eab15e26132 118 Gene3D G3DSA:1.10.10.60 8 84 5.7E-23 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS19100 ca56b70754b7c70da7559eab15e26132 118 SUPERFAMILY SSF46689 1 84 2.87E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS19100 ca56b70754b7c70da7559eab15e26132 118 Pfam PF01527 Transposase 4 70 2.9E-18 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS22560 f69328aa93180d8783b031f8cf99c089 76 Gene3D G3DSA:1.10.10.10 9 62 5.4E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22560 f69328aa93180d8783b031f8cf99c089 76 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 9 57 1.6E-15 T 10-03-2017 IPR010260 Prophage CP4-57 regulatory protein (AlpA) RG49_RS22560 f69328aa93180d8783b031f8cf99c089 76 SUPERFAMILY SSF46955 9 66 4.03E-6 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS00925 a70e90edde8776f506c853f43a0c41e7 119 SUPERFAMILY SSF140670 23 119 3.53E-53 T 10-03-2017 RG49_RS00925 a70e90edde8776f506c853f43a0c41e7 119 Pfam PF08986 Domain of unknown function (DUF1889) 1 119 3.0E-83 T 10-03-2017 IPR015079 Protein of unknown function DUF1889 RG49_RS11665 38b4db6538bce110ff050407026631c8 504 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 500 2.3E-127 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS11665 38b4db6538bce110ff050407026631c8 504 Hamap MF_01049 L-carnitine/gamma-butyrobetaine antiporter [caiT]. 1 504 63.245 T 10-03-2017 IPR023449 L-carnitine/gamma-butyrobetaine antiporter CaiT GO:0016020|GO:0044667|GO:1900749|GO:1900751 RG49_RS11665 38b4db6538bce110ff050407026631c8 504 ProSitePatterns PS01303 BCCT family of transporters signature. 315 324 - T 10-03-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS11665 38b4db6538bce110ff050407026631c8 504 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 52 501 1.0E-168 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS16830 2e6477a5828faa4bb31e32492e007a94 63 TIGRFAM TIGR03493 cellullose_BcsF: celllulose biosynthesis operon protein BcsF/YhjT 2 63 1.0E-34 T 10-03-2017 IPR019995 Cellulose biosynthesis, BcsF/YhjT RG49_RS16830 2e6477a5828faa4bb31e32492e007a94 63 Pfam PF11120 Cellulose biosynthesis protein BcsF 2 60 3.9E-30 T 10-03-2017 IPR019995 Cellulose biosynthesis, BcsF/YhjT RG49_RS16830 2e6477a5828faa4bb31e32492e007a94 63 ProDom PD053231 YHJT MEMBRANE INNER BCSF 2 63 6.0E-29 T 10-03-2017 IPR019995 Cellulose biosynthesis, BcsF/YhjT RG49_RS01450 2b152b67d38b3ef1e9de4703d23adf22 327 SUPERFAMILY SSF55681 92 327 6.3E-82 T 10-03-2017 RG49_RS01450 2b152b67d38b3ef1e9de4703d23adf22 327 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 327 2.7E-119 T 10-03-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 RG49_RS01450 2b152b67d38b3ef1e9de4703d23adf22 327 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 326 50.145 T 10-03-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 RG49_RS01450 2b152b67d38b3ef1e9de4703d23adf22 327 Pfam PF01409 tRNA synthetases class II core domain (F) 92 326 2.8E-107 T 10-03-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 RG49_RS01450 2b152b67d38b3ef1e9de4703d23adf22 327 Gene3D G3DSA:3.30.930.10 9 327 2.6E-135 T 10-03-2017 RG49_RS01450 2b152b67d38b3ef1e9de4703d23adf22 327 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 1.5E-27 T 10-03-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 RG49_RS01450 2b152b67d38b3ef1e9de4703d23adf22 327 SUPERFAMILY SSF46589 14 99 8.89E-23 T 10-03-2017 IPR010978 tRNA-binding arm GO:0000166 RG49_RS18670 8f27ec0d780bfc7bb9f01b24673b9a1a 260 Pfam PF02405 Permease MlaE 44 256 5.5E-73 T 10-03-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 RG49_RS18670 8f27ec0d780bfc7bb9f01b24673b9a1a 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 258 5.4E-107 T 10-03-2017 IPR003453 ABC transport permease subunit MlaE, Proteobacteria RG49_RS02720 201949c6b1eaaffb56c96c5bdb06aa20 775 Gene3D G3DSA:3.40.50.300 608 749 2.0E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02720 201949c6b1eaaffb56c96c5bdb06aa20 775 Gene3D G3DSA:3.40.50.300 5 191 2.0E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02720 201949c6b1eaaffb56c96c5bdb06aa20 775 Pfam PF13476 AAA domain 8 243 2.4E-14 T 10-03-2017 RG49_RS02720 201949c6b1eaaffb56c96c5bdb06aa20 775 SUPERFAMILY SSF52540 576 751 3.03E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02720 201949c6b1eaaffb56c96c5bdb06aa20 775 SUPERFAMILY SSF52540 5 244 3.03E-25 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08275 8d241ef618e7f1fecb13aacce1696495 122 Pfam PF04237 YjbR 15 106 1.1E-20 T 10-03-2017 IPR007351 Uncharacterised protein YjbR RG49_RS08275 8d241ef618e7f1fecb13aacce1696495 122 SUPERFAMILY SSF142906 8 119 6.67E-36 T 10-03-2017 RG49_RS08440 3714041152f9e4513d50ba46fec255b0 173 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 167 1.0E-33 T 10-03-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase RG49_RS08950 a3aebedd25ddedfe1ade83d1e8475627 105 SUPERFAMILY SSF82657 1 89 7.85E-31 T 10-03-2017 IPR002634 BolA protein RG49_RS08950 a3aebedd25ddedfe1ade83d1e8475627 105 Pfam PF01722 BolA-like protein 11 84 1.7E-29 T 10-03-2017 IPR002634 BolA protein RG49_RS08950 a3aebedd25ddedfe1ade83d1e8475627 105 PIRSF PIRSF003113 1 100 9.8E-34 T 10-03-2017 IPR002634 BolA protein RG49_RS08950 a3aebedd25ddedfe1ade83d1e8475627 105 Gene3D G3DSA:3.30.300.90 1 101 5.0E-32 T 10-03-2017 IPR002634 BolA protein RG49_RS22180 802a622f16887530be1ab825e4ad3e5c 216 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 132 186 5.6E-26 T 10-03-2017 IPR005573 Anti sigma-E protein RseA, C-terminal RG49_RS22180 802a622f16887530be1ab825e4ad3e5c 216 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 1 87 3.6E-37 T 10-03-2017 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 RG49_RS22180 802a622f16887530be1ab825e4ad3e5c 216 SUPERFAMILY SSF89069 1 66 1.44E-22 T 10-03-2017 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 RG49_RS22180 802a622f16887530be1ab825e4ad3e5c 216 PIRSF PIRSF016938 1 205 4.1E-37 T 10-03-2017 IPR026279 Sigma-E factor negative regulatory protein RseA GO:0006950|GO:0016989 RG49_RS06215 61b646950d110aff8f6777315807ff2b 285 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 83 92 - T 10-03-2017 IPR024002 Formate/nitrite transporter, conserved site RG49_RS06215 61b646950d110aff8f6777315807ff2b 285 TIGRFAM TIGR04060 formate_focA: formate transporter FocA 14 279 7.9E-129 T 10-03-2017 IPR023999 Formate transporter FocA, putative GO:0015499|GO:0015724|GO:0016021 RG49_RS06215 61b646950d110aff8f6777315807ff2b 285 Gene3D G3DSA:1.20.1080.10 29 280 8.6E-91 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS06215 61b646950d110aff8f6777315807ff2b 285 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 168 178 - T 10-03-2017 IPR024002 Formate/nitrite transporter, conserved site RG49_RS06215 61b646950d110aff8f6777315807ff2b 285 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 26 280 4.6E-98 T 10-03-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 RG49_RS06215 61b646950d110aff8f6777315807ff2b 285 Pfam PF01226 Formate/nitrite transporter 15 276 2.7E-76 T 10-03-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 Gene3D G3DSA:3.40.190.10 89 190 1.4E-18 T 10-03-2017 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 SUPERFAMILY SSF53850 89 295 5.07E-30 T 10-03-2017 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-8 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 Gene3D G3DSA:1.10.10.10 1 85 3.2E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 Pfam PF03466 LysR substrate binding domain 87 289 4.8E-32 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.9E-22 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 Gene3D G3DSA:3.40.190.10 191 245 1.4E-11 T 10-03-2017 RG49_RS25330 5c39f6f71d7ca84697ea28f968cf0fa5 305 SUPERFAMILY SSF46785 1 86 5.3E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS10160 4ad5ef0650a906ffe34f5e98184ff266 116 Gene3D G3DSA:1.10.260.40 5 98 1.4E-13 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS10160 4ad5ef0650a906ffe34f5e98184ff266 116 Pfam PF12844 Helix-turn-helix domain 6 67 3.0E-11 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS10160 4ad5ef0650a906ffe34f5e98184ff266 116 SUPERFAMILY SSF47413 3 65 2.28E-11 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS10160 4ad5ef0650a906ffe34f5e98184ff266 116 SMART SM00530 8 63 3.5E-6 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS02190 cdecf079fd932332cf157296026d0a50 431 Gene3D G3DSA:1.10.150.130 85 197 6.4E-10 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS02190 cdecf079fd932332cf157296026d0a50 431 Gene3D G3DSA:1.10.443.10 203 408 3.2E-40 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02190 cdecf079fd932332cf157296026d0a50 431 Pfam PF12167 Domain of unknown function (DUF3596) 9 72 7.2E-24 T 10-03-2017 IPR022000 Domain of unknown function (DUF3596) RG49_RS02190 cdecf079fd932332cf157296026d0a50 431 Pfam PF00589 Phage integrase family 206 397 1.3E-19 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02190 cdecf079fd932332cf157296026d0a50 431 SUPERFAMILY SSF56349 84 403 7.36E-55 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS05425 564233cc09f9d1c7cf9967ffcf8472f6 177 SUPERFAMILY SSF52949 3 172 3.7E-64 T 10-03-2017 RG49_RS05425 564233cc09f9d1c7cf9967ffcf8472f6 177 Pfam PF01661 Macro domain 21 137 1.1E-41 T 10-03-2017 IPR002589 Macro domain RG49_RS05425 564233cc09f9d1c7cf9967ffcf8472f6 177 SMART SM00506 4 137 3.5E-58 T 10-03-2017 IPR002589 Macro domain RG49_RS05425 564233cc09f9d1c7cf9967ffcf8472f6 177 Hamap MF_01205 O-acetyl-ADP-ribose deacetylase [ymdB]. 2 172 48.2 T 10-03-2017 IPR024900 O-acetyl-ADP-ribose deacetylase RG49_RS05425 564233cc09f9d1c7cf9967ffcf8472f6 177 Gene3D G3DSA:3.40.220.10 3 174 1.9E-70 T 10-03-2017 RG49_RS02495 0e52289f6b5bd63eedd1187028ffd02c 427 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 1 390 1.7E-136 T 10-03-2017 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 RG49_RS02495 0e52289f6b5bd63eedd1187028ffd02c 427 Pfam PF00083 Sugar (and other) transporter 30 191 4.1E-21 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS02495 0e52289f6b5bd63eedd1187028ffd02c 427 SUPERFAMILY SSF103473 3 406 8.24E-57 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS02495 0e52289f6b5bd63eedd1187028ffd02c 427 Pfam PF07690 Major Facilitator Superfamily 256 410 2.1E-12 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS02495 0e52289f6b5bd63eedd1187028ffd02c 427 Gene3D G3DSA:1.20.1250.20 213 402 2.1E-14 T 10-03-2017 RG49_RS02495 0e52289f6b5bd63eedd1187028ffd02c 427 Gene3D G3DSA:1.20.1250.20 29 194 2.0E-23 T 10-03-2017 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 5 738 0.0 T 10-03-2017 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 SUPERFAMILY SSF56719 28 479 3.66E-154 T 10-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 SUPERFAMILY SSF101904 494 736 1.26E-50 T 10-03-2017 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 1 738 34.376 T 10-03-2017 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Gene3D G3DSA:3.90.199.10 27 234 1.3E-105 T 10-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Gene3D G3DSA:3.90.199.10 330 395 1.3E-105 T 10-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 465 1.3E-134 T 10-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 641 675 2.8E-8 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 593 630 5.3E-4 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Gene3D G3DSA:2.120.10.90 493 726 3.0E-27 T 10-03-2017 RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 Gene3D G3DSA:3.30.1360.40 235 328 8.1E-25 T 10-03-2017 IPR024946 Arginine repressor C-terminal-like domain RG49_RS19655 a8ab4921f417360aa1025821a5f3de3c 752 SMART SM00434 8 458 4.8E-241 T 10-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS06735 148e5d9b88aa30dfdbb66a5141d76a5f 77 ProDom PD057914 C0939 STY4639 GPA GP33 PRECURSOR FELS-2 5'REGION STY3665 SIGNAL PHAGE-RELATED 1 77 2.0E-22 T 10-03-2017 IPR020126 Protein of unknown function DUF2732 RG49_RS06735 148e5d9b88aa30dfdbb66a5141d76a5f 77 Pfam PF10809 Protein of unknown function (DUF2732) 1 76 2.6E-26 T 10-03-2017 IPR020126 Protein of unknown function DUF2732 RG49_RS00380 fa5738dadb5667192f2310a3a38c5df2 79 Pfam PF10678 Protein of unknown function (DUF2492) 3 78 1.1E-36 T 10-03-2017 IPR019620 Putative metal-binding protein RG49_RS00380 fa5738dadb5667192f2310a3a38c5df2 79 TIGRFAM TIGR03853 matur_matur: putative metal-binding protein 3 79 9.6E-36 T 10-03-2017 IPR019620 Putative metal-binding protein RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.3E-53 T 10-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.4E-42 T 10-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.4E-42 T 10-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.4E-42 T 10-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 31.068 T 10-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 4.0E-14 T 10-03-2017 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 Gene3D G3DSA:1.10.1900.20 55 117 3.7E-31 T 10-03-2017 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 SUPERFAMILY SSF74731 3 117 2.62E-50 T 10-03-2017 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 Pfam PF00453 Ribosomal protein L20 3 109 3.9E-49 T 10-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS01435 fde9fa85e2bb35caa2b2d6f368888a0a 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 10-03-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS03930 48db9e65d08ec3300ab00844891161d9 353 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 54 341 1.6E-150 T 10-03-2017 IPR006507 Uncharacterised protein family UPF0283 RG49_RS03930 48db9e65d08ec3300ab00844891161d9 353 Hamap MF_01085 UPF0283 membrane protein YcjF [ycjF]. 4 347 39.242 T 10-03-2017 IPR006507 Uncharacterised protein family UPF0283 RG49_RS03930 48db9e65d08ec3300ab00844891161d9 353 Pfam PF05128 Domain of unknown function (DUF697) 183 341 1.0E-53 T 10-03-2017 IPR021147 Protein of unknown function DUF697 RG49_RS25015 17a96b69168e0a2bd7f740bf45af1ca2 180 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 174 5.2E-83 T 10-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 RG49_RS25015 17a96b69168e0a2bd7f740bf45af1ca2 180 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 169 2.0E-74 T 10-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 RG49_RS25015 17a96b69168e0a2bd7f740bf45af1ca2 180 Gene3D G3DSA:2.60.120.10 1 175 3.5E-84 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS25015 17a96b69168e0a2bd7f740bf45af1ca2 180 SUPERFAMILY SSF51182 1 176 1.29E-78 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS25015 17a96b69168e0a2bd7f740bf45af1ca2 180 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 174 2.6E-75 T 10-03-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 RG49_RS23025 50628d3728e7f0bb038d81c553202a46 244 Pfam PF05406 WGR domain 9 71 1.5E-16 T 10-03-2017 IPR008893 WGR domain RG49_RS23025 50628d3728e7f0bb038d81c553202a46 244 SMART SM00773 1 72 1.5E-20 T 10-03-2017 IPR008893 WGR domain RG49_RS23025 50628d3728e7f0bb038d81c553202a46 244 SUPERFAMILY SSF142921 11 81 4.45E-12 T 10-03-2017 IPR008893 WGR domain RG49_RS23025 50628d3728e7f0bb038d81c553202a46 244 Gene3D G3DSA:2.20.140.10 1 73 8.9E-29 T 10-03-2017 IPR008893 WGR domain RG49_RS23025 50628d3728e7f0bb038d81c553202a46 244 PIRSF PIRSF026317 1 244 9.3E-147 T 10-03-2017 IPR016835 Uncharacterised conserved protein UCP026317, WGR RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PIRSF PIRSF019404 1 147 5.4E-52 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PRINTS PR01004 Flagellar FliJ protein signature 4 26 1.8E-82 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PRINTS PR01004 Flagellar FliJ protein signature 27 43 1.8E-82 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PRINTS PR01004 Flagellar FliJ protein signature 63 84 1.8E-82 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PRINTS PR01004 Flagellar FliJ protein signature 86 107 1.8E-82 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PRINTS PR01004 Flagellar FliJ protein signature 108 126 1.8E-82 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PRINTS PR01004 Flagellar FliJ protein signature 126 146 1.8E-82 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 PRINTS PR01004 Flagellar FliJ protein signature 44 61 1.8E-82 T 10-03-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 144 3.1E-31 T 10-03-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 RG49_RS00200 85bd5ad895f495dbece885dcfbf13b5d 147 Pfam PF02050 Flagellar FliJ protein 19 141 1.4E-34 T 10-03-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 RG49_RS20900 9e23702219d06826b81dbc87632ba4fd 291 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 280 5.9E-77 T 10-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 RG49_RS20900 9e23702219d06826b81dbc87632ba4fd 291 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 142 154 - T 10-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 RG49_RS20900 9e23702219d06826b81dbc87632ba4fd 291 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 287 1.4E-113 T 10-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 RG49_RS20900 9e23702219d06826b81dbc87632ba4fd 291 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 285 20.632 T 10-03-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 RG49_RS25300 bb9e6b22c5252abb6a4d9c8337ee474c 267 Pfam PF12835 Integrase 102 250 1.4E-55 T 10-03-2017 IPR024456 Integrase catalytic domain, putative RG49_RS25300 bb9e6b22c5252abb6a4d9c8337ee474c 267 Gene3D G3DSA:1.10.443.10 113 253 2.1E-7 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS25300 bb9e6b22c5252abb6a4d9c8337ee474c 267 SUPERFAMILY SSF56349 13 253 3.53E-17 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS25300 bb9e6b22c5252abb6a4d9c8337ee474c 267 Pfam PF12834 Phage integrase, N-terminal 1 91 9.4E-37 T 10-03-2017 IPR024457 Putative integrase, N-terminal RG49_RS25400 bb9e6b22c5252abb6a4d9c8337ee474c 267 Pfam PF12835 Integrase 102 250 1.4E-55 T 10-03-2017 IPR024456 Integrase catalytic domain, putative RG49_RS25400 bb9e6b22c5252abb6a4d9c8337ee474c 267 Gene3D G3DSA:1.10.443.10 113 253 2.1E-7 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS25400 bb9e6b22c5252abb6a4d9c8337ee474c 267 SUPERFAMILY SSF56349 13 253 3.53E-17 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS25400 bb9e6b22c5252abb6a4d9c8337ee474c 267 Pfam PF12834 Phage integrase, N-terminal 1 91 9.4E-37 T 10-03-2017 IPR024457 Putative integrase, N-terminal RG49_RS14165 bb3e0d7cf8c73e995b255695bc36b470 165 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 78 161 1.0E-4 T 10-03-2017 RG49_RS14165 bb3e0d7cf8c73e995b255695bc36b470 165 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 10-03-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14165 bb3e0d7cf8c73e995b255695bc36b470 165 Pfam PF00466 Ribosomal protein L10 5 101 6.2E-26 T 10-03-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 RG49_RS14165 bb3e0d7cf8c73e995b255695bc36b470 165 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 162 26.856 T 10-03-2017 IPR022973 Ribosomal protein L10 RG49_RS14165 bb3e0d7cf8c73e995b255695bc36b470 165 SUPERFAMILY SSF160369 4 160 2.48E-48 T 10-03-2017 RG49_RS00295 731ce426a45666832338679bfa10c254 183 TIGRFAM TIGR03823 FliZ: flagellar regulatory protein FliZ 1 167 2.4E-91 T 10-03-2017 IPR022523 Flagellar regulator, FliZ RG49_RS00295 731ce426a45666832338679bfa10c254 183 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 90 164 2.3E-13 T 10-03-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 579 619 7.3E-12 T 10-03-2017 IPR006530 YD repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 641 681 7.1E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 455 487 0.0019 T 10-03-2017 IPR006530 YD repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 493 518 2.1E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 600 631 5.4E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 540 572 6.5E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 413 448 4.1E-7 T 10-03-2017 IPR006530 YD repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 PRINTS PR00394 RHS protein signature 1179 1194 1.2E-51 T 10-03-2017 IPR001826 RHS protein RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 PRINTS PR00394 RHS protein signature 1110 1129 1.2E-51 T 10-03-2017 IPR001826 RHS protein RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 PRINTS PR00394 RHS protein signature 1148 1168 1.2E-51 T 10-03-2017 IPR001826 RHS protein RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 PRINTS PR00394 RHS protein signature 1226 1245 1.2E-51 T 10-03-2017 IPR001826 RHS protein RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 PRINTS PR00394 RHS protein signature 1203 1223 1.2E-51 T 10-03-2017 IPR001826 RHS protein RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 Pfam PF03527 RHS protein 1154 1190 5.5E-16 T 10-03-2017 IPR001826 RHS protein RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1181 1258 2.2E-24 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 Pfam PF05593 RHS Repeat 320 357 5.0E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 Pfam PF05593 RHS Repeat 579 615 1.7E-10 T 10-03-2017 IPR031325 RHS repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 Pfam PF05593 RHS Repeat 413 444 8.5E-7 T 10-03-2017 IPR031325 RHS repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 Pfam PF05593 RHS Repeat 539 572 1.2E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 Pfam PF05593 RHS Repeat 493 532 1.2E-4 T 10-03-2017 IPR031325 RHS repeat RG49_RS03095 fed49ba4ad8cf530e7cf713848880387 1407 Pfam PF05593 RHS Repeat 621 656 6.8E-5 T 10-03-2017 IPR031325 RHS repeat RG49_RS22995 5c51b9de041df249451496766b6b5469 263 SUPERFAMILY SSF51735 6 255 3.17E-86 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.9E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.9E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.9E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 1.5E-4 T 10-03-2017 RG49_RS22995 5c51b9de041df249451496766b6b5469 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 1.5E-71 T 10-03-2017 RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.3E-45 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.3E-45 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.3E-45 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 4.3E-45 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.3E-45 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.3E-45 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS22995 5c51b9de041df249451496766b6b5469 263 Gene3D G3DSA:3.40.50.720 1 254 1.3E-91 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16825 3d8b03e439b3927ee39c8eee7feb29ea 559 TIGRFAM TIGR03368 cellulose_yhjU: cellulose synthase operon protein YhjU 23 557 1.1E-246 T 10-03-2017 IPR017744 Cellulose biosynthesis protein BcsG RG49_RS16825 3d8b03e439b3927ee39c8eee7feb29ea 559 Pfam PF11658 Cellulose biosynthesis protein BcsG 24 554 1.4E-236 T 10-03-2017 IPR017744 Cellulose biosynthesis protein BcsG RG49_RS17680 6a08bdde1ce1a7aea4f29bc619d2f285 120 Gene3D G3DSA:1.10.1790.10 15 108 2.0E-7 T 10-03-2017 IPR011608 PRD domain GO:0006355 RG49_RS17680 6a08bdde1ce1a7aea4f29bc619d2f285 120 SUPERFAMILY SSF63520 15 111 1.83E-7 T 10-03-2017 IPR011608 PRD domain GO:0006355 RG49_RS17105 c3e9eade2eb57760ca7c63fc11f0ee01 350 Pfam PF10951 Protein of unknown function (DUF2776) 2 347 1.3E-151 T 10-03-2017 IPR021240 Protein of unknown function DUF2776 RG49_RS19145 806d23732eecf3a07d4a5478b9c46f34 129 Gene3D G3DSA:3.30.1330.40 2 127 3.5E-46 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS19145 806d23732eecf3a07d4a5478b9c46f34 129 SUPERFAMILY SSF55298 3 127 4.87E-42 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS19145 806d23732eecf3a07d4a5478b9c46f34 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 126 5.4E-54 T 10-03-2017 IPR006056 RidA family RG49_RS19145 806d23732eecf3a07d4a5478b9c46f34 129 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 10-03-2017 IPR019897 RidA, conserved site RG49_RS19145 806d23732eecf3a07d4a5478b9c46f34 129 Pfam PF01042 Endoribonuclease L-PSP 8 126 3.3E-44 T 10-03-2017 IPR006175 YjgF/YER057c/UK114 family RG49_RS14675 bca2e9e0d6165326dffaadbf8f70637f 351 Pfam PF12889 Protein of unknown function (DUF3829) 74 349 1.2E-89 T 10-03-2017 IPR024291 Protein of unknown function DUF3829 RG49_RS08850 6087b77aea927d65738bb3396fb39f38 129 Gene3D G3DSA:1.10.10.10 31 115 3.8E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08850 6087b77aea927d65738bb3396fb39f38 129 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 33 112 4.0E-26 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS08850 6087b77aea927d65738bb3396fb39f38 129 SUPERFAMILY SSF46767 31 113 2.62E-26 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS08850 6087b77aea927d65738bb3396fb39f38 129 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 32 102 7.1E-15 T 10-03-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 RG49_RS20990 c1e3800a5640820e3df98e8023db8756 147 Gene3D G3DSA:3.90.1010.10 4 146 2.0E-48 T 10-03-2017 RG49_RS20990 c1e3800a5640820e3df98e8023db8756 147 SUPERFAMILY SSF82649 3 145 1.2E-43 T 10-03-2017 RG49_RS20990 c1e3800a5640820e3df98e8023db8756 147 Pfam PF02657 Fe-S metabolism associated domain 23 140 2.2E-38 T 10-03-2017 IPR003808 Fe-S metabolism associated domain, SufE-like RG49_RS20990 c1e3800a5640820e3df98e8023db8756 147 TIGRFAM TIGR03391 FeS_syn_CsdE: cysteine desulfurase, sulfur acceptor subunit CsdE 7 143 4.0E-73 T 10-03-2017 IPR017763 Cysteine desulfurase, sulphur acceptor subunit CsdE RG49_RS11980 298a94e68b859667f2f6e80c04f005b7 214 Pfam PF10144 Bacterial virulence factor haemolysin 1 160 4.7E-67 T 10-03-2017 IPR019305 Uncharacterised protein family Smp RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.5E-10 T 10-03-2017 RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 Gene3D G3DSA:3.40.1190.20 60 339 6.0E-62 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 93 117 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 SUPERFAMILY SSF46785 1 54 6.17E-8 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 Gene3D G3DSA:1.10.10.10 1 56 5.9E-9 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 SUPERFAMILY SSF53613 61 340 1.11E-52 T 10-03-2017 IPR029056 Ribokinase-like RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 Pfam PF00294 pfkB family carbohydrate kinase 58 348 5.4E-65 T 10-03-2017 IPR011611 Carbohydrate kinase PfkB RG49_RS24355 73175ae3c97b07fa6aa7a76022803a31 362 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 303 316 - T 10-03-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 RG49_RS13730 51aaf3dcb27be7b8784c06c1895d0b3c 178 PIRSF PIRSF002070 2 161 1.1E-41 T 10-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 RG49_RS13730 51aaf3dcb27be7b8784c06c1895d0b3c 178 SUPERFAMILY SSF50249 4 178 1.34E-63 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13730 51aaf3dcb27be7b8784c06c1895d0b3c 178 Pfam PF00436 Single-strand binding protein family 6 112 8.5E-43 T 10-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 RG49_RS13730 51aaf3dcb27be7b8784c06c1895d0b3c 178 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 178 3.2E-62 T 10-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 RG49_RS13730 51aaf3dcb27be7b8784c06c1895d0b3c 178 Gene3D G3DSA:2.40.50.140 4 178 4.6E-60 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS13730 51aaf3dcb27be7b8784c06c1895d0b3c 178 Hamap MF_00984 Single-stranded DNA-binding protein. 6 117 40.014 T 10-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 RG49_RS12885 0a51a4f0cd061303cf59e8c0e2739976 425 Pfam PF07690 Major Facilitator Superfamily 15 323 1.9E-52 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS12885 0a51a4f0cd061303cf59e8c0e2739976 425 SUPERFAMILY SSF103473 4 412 1.05E-84 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS12885 0a51a4f0cd061303cf59e8c0e2739976 425 Gene3D G3DSA:1.20.1250.20 5 199 2.4E-51 T 10-03-2017 RG49_RS12885 0a51a4f0cd061303cf59e8c0e2739976 425 Gene3D G3DSA:1.20.1250.20 216 414 7.8E-21 T 10-03-2017 RG49_RS12885 0a51a4f0cd061303cf59e8c0e2739976 425 PIRSF PIRSF002808 1 424 3.1E-43 T 10-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS09455 3c82b8c8623b2163e003343cee9f1b6c 419 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 11 397 3.1E-82 T 10-03-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 RG49_RS03690 759bca27c6db4af4744c0709fe08ad2b 140 Pfam PF06163 Bacterial protein of unknown function (DUF977) 2 135 9.1E-31 T 10-03-2017 IPR010382 Protein of unknown function DUF977 RG49_RS05155 14a046f64260012ee400933c501ee8b5 213 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 200 2.5E-70 T 10-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 RG49_RS05155 14a046f64260012ee400933c501ee8b5 213 Hamap MF_00165 Thymidylate kinase [tmk]. 4 208 28.385 T 10-03-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 RG49_RS05155 14a046f64260012ee400933c501ee8b5 213 Gene3D G3DSA:3.40.50.300 2 209 7.0E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05155 14a046f64260012ee400933c501ee8b5 213 SUPERFAMILY SSF52540 1 209 9.53E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05155 14a046f64260012ee400933c501ee8b5 213 ProSitePatterns PS01331 Thymidylate kinase signature. 97 109 - T 10-03-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 RG49_RS05155 14a046f64260012ee400933c501ee8b5 213 Pfam PF02223 Thymidylate kinase 8 200 5.9E-61 T 10-03-2017 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 506 1.1E-153 T 10-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 SUPERFAMILY SSF56719 30 521 3.14E-182 T 10-03-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Gene3D G3DSA:3.90.199.10 34 216 2.3E-84 T 10-03-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Gene3D G3DSA:3.30.1360.40 236 333 2.9E-38 T 10-03-2017 IPR024946 Arginine repressor C-terminal-like domain RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Gene3D G3DSA:2.120.10.90 531 839 5.2E-139 T 10-03-2017 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Gene3D G3DSA:1.10.268.10 363 496 2.8E-49 T 10-03-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 SUPERFAMILY SSF101904 533 851 5.36E-111 T 10-03-2017 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 841 24.557 T 10-03-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 646 688 3.9E-7 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 692 737 8.1E-15 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 538 584 2.0E-10 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 744 789 1.0E-13 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 588 637 7.5E-11 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 793 839 9.3E-13 T 10-03-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 840 0.0 T 10-03-2017 RG49_RS23960 76463a0cc647d9eaf9e912ca32648522 875 SMART SM00434 11 499 4.5E-301 T 10-03-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 RG49_RS00315 957b3181422a84deb1c4730290046581 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS00315 957b3181422a84deb1c4730290046581 250 SUPERFAMILY SSF52540 4 243 1.52E-78 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00315 957b3181422a84deb1c4730290046581 250 SMART SM00382 28 221 3.2E-20 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS00315 957b3181422a84deb1c4730290046581 250 PIRSF PIRSF039085 1 249 4.2E-112 T 10-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 RG49_RS00315 957b3181422a84deb1c4730290046581 250 Pfam PF00005 ABC transporter 19 173 3.4E-36 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS00315 957b3181422a84deb1c4730290046581 250 Gene3D G3DSA:3.40.50.300 3 245 1.9E-87 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08265 87fd4cf28a31877cbb093c6d3865ba8c 372 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 372 93.066 T 10-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 RG49_RS08265 87fd4cf28a31877cbb093c6d3865ba8c 372 SUPERFAMILY SSF55931 4 369 3.27E-109 T 10-03-2017 RG49_RS08265 87fd4cf28a31877cbb093c6d3865ba8c 372 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 14 292 1.3E-93 T 10-03-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 RG49_RS08265 87fd4cf28a31877cbb093c6d3865ba8c 372 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 13 296 7.2E-119 T 10-03-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 RG49_RS14540 a5f1cb3d40319f9a61f8a22a26803fb1 251 Gene3D G3DSA:3.30.428.30 26 251 3.6E-108 T 10-03-2017 RG49_RS14540 a5f1cb3d40319f9a61f8a22a26803fb1 251 PIRSF PIRSF001273 1 251 2.3E-112 T 10-03-2017 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 RG49_RS14540 a5f1cb3d40319f9a61f8a22a26803fb1 251 Pfam PF02611 CDP-diacylglycerol pyrophosphatase 31 249 1.1E-92 T 10-03-2017 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 RG49_RS14540 a5f1cb3d40319f9a61f8a22a26803fb1 251 TIGRFAM TIGR00672 cdh: CDP-diacylglycerol diphosphatase 1 251 5.9E-163 T 10-03-2017 IPR015993 CDP-diacylglycerol pyrophosphatase, proteobacterial GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 RG49_RS14540 a5f1cb3d40319f9a61f8a22a26803fb1 251 SUPERFAMILY SSF54197 31 249 4.93E-91 T 10-03-2017 IPR011146 HIT-like domain GO:0003824 RG49_RS14540 a5f1cb3d40319f9a61f8a22a26803fb1 251 Hamap MF_00319 CDP-diacylglycerol pyrophosphatase [cdh]. 1 251 58.074 T 10-03-2017 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 RG49_RS05265 301d9eb9242556c6164f2bcbeb1fa61f 402 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 10-03-2017 IPR019776 Flagellar basal body rod protein, conserved site RG49_RS05265 301d9eb9242556c6164f2bcbeb1fa61f 402 SUPERFAMILY SSF117143 73 363 3.79E-83 T 10-03-2017 RG49_RS05265 301d9eb9242556c6164f2bcbeb1fa61f 402 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 384 2.9E-96 T 10-03-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G RG49_RS05265 301d9eb9242556c6164f2bcbeb1fa61f 402 Pfam PF07559 Flagellar basal body protein FlaE 173 283 1.3E-20 T 10-03-2017 IPR011491 Flagellar hook protein FlgE RG49_RS05265 301d9eb9242556c6164f2bcbeb1fa61f 402 Pfam PF00460 Flagella basal body rod protein 4 33 1.1E-11 T 10-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 RG49_RS05265 301d9eb9242556c6164f2bcbeb1fa61f 402 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 324 401 2.5E-20 T 10-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain RG49_RS10110 57a7e20d385a1dfe5a3279b27d9bd58d 155 ProDom PD034160 PRECURSOR SIGNAL YFJT INTERGENIC-REGION C0283 YKFB 1 155 7.0E-71 T 10-03-2017 RG49_RS01715 4d2a0cc7b7a42829648e74396df42212 418 Pfam PF03212 Pertactin 329 403 1.9E-5 T 10-03-2017 IPR004899 Pertactin, central region RG49_RS01715 4d2a0cc7b7a42829648e74396df42212 418 Gene3D G3DSA:2.160.20.20 11 393 4.6E-14 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS01715 4d2a0cc7b7a42829648e74396df42212 418 SUPERFAMILY SSF51126 39 394 1.73E-11 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS01715 4d2a0cc7b7a42829648e74396df42212 418 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 149 179 5.9E-5 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS01715 4d2a0cc7b7a42829648e74396df42212 418 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 31 69 1.9E-6 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS01715 4d2a0cc7b7a42829648e74396df42212 418 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 99 159 1.5E-20 T 10-03-2017 IPR030930 Adhesin of bacterial autotransporter system RG49_RS13745 ab5227f9f7cac5ee0aa61af2bc9c67d5 138 SUPERFAMILY SSF111038 1 138 3.01E-46 T 10-03-2017 IPR001602 Uncharacterised protein family UPF0047 RG49_RS13745 ab5227f9f7cac5ee0aa61af2bc9c67d5 138 Gene3D G3DSA:2.60.120.460 1 138 7.2E-55 T 10-03-2017 IPR001602 Uncharacterised protein family UPF0047 RG49_RS13745 ab5227f9f7cac5ee0aa61af2bc9c67d5 138 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 99 117 - T 10-03-2017 IPR001602 Uncharacterised protein family UPF0047 RG49_RS13745 ab5227f9f7cac5ee0aa61af2bc9c67d5 138 PIRSF PIRSF004681 1 138 2.0E-42 T 10-03-2017 IPR001602 Uncharacterised protein family UPF0047 RG49_RS13745 ab5227f9f7cac5ee0aa61af2bc9c67d5 138 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 138 3.4E-54 T 10-03-2017 IPR001602 Uncharacterised protein family UPF0047 RG49_RS13745 ab5227f9f7cac5ee0aa61af2bc9c67d5 138 Pfam PF01894 Uncharacterised protein family UPF0047 19 134 3.5E-35 T 10-03-2017 IPR001602 Uncharacterised protein family UPF0047 RG49_RS14090 9f04afa78cf67b2eff76743038ca0735 196 Pfam PF04222 Protein of unknown function (DUF416) 5 192 1.0E-83 T 10-03-2017 IPR007338 Protein of unknown function DUF416 RG49_RS14090 9f04afa78cf67b2eff76743038ca0735 196 Gene3D G3DSA:1.20.1590.10 1 192 2.8E-93 T 10-03-2017 IPR023381 YP001051499.1-like domain RG49_RS19915 a877b45cd5ab13c71ade9f179fbb0c9c 134 Pfam PF03928 Haem-degrading 7 129 1.4E-32 T 10-03-2017 IPR005624 Haem-degrading RG49_RS19915 a877b45cd5ab13c71ade9f179fbb0c9c 134 SUPERFAMILY SSF143744 2 132 1.26E-36 T 10-03-2017 RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.632 T 10-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 2.1E-22 T 10-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 SUPERFAMILY SSF55653 60 149 1.07E-25 T 10-03-2017 IPR020069 Ribosomal protein L9, C-terminal RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 Gene3D G3DSA:3.40.5.10 1 52 1.5E-25 T 10-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 SUPERFAMILY SSF55658 1 57 3.31E-19 T 10-03-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 2.3E-25 T 10-03-2017 IPR020069 Ribosomal protein L9, C-terminal RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 Gene3D G3DSA:3.10.430.100 61 149 1.7E-28 T 10-03-2017 IPR020069 Ribosomal protein L9, C-terminal RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 10-03-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS12890 32db77dafcb2b4bb72dcbe9329a202fe 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 1.8E-59 T 10-03-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17020 a6d31d6ad8566e43cddbbb108403945e 407 SUPERFAMILY SSF141571 209 253 1.57E-5 T 10-03-2017 RG49_RS00910 f95ae123c40bcc34ed04911293b82ecd 192 ProSitePatterns PS01293 Nudix CoA signature. 47 67 - T 10-03-2017 IPR000059 NUDIX hydrolase, NudL, conserved site GO:0000287|GO:0009132|GO:0016818|GO:0030145 Reactome: R-HSA-390918 RG49_RS00910 f95ae123c40bcc34ed04911293b82ecd 192 SUPERFAMILY SSF55811 8 181 3.11E-35 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS00910 f95ae123c40bcc34ed04911293b82ecd 192 Gene3D G3DSA:3.90.79.10 26 185 1.9E-39 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS00910 f95ae123c40bcc34ed04911293b82ecd 192 Pfam PF00293 NUDIX domain 30 143 1.4E-14 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS24905 970b4d613a04026865116f0add6e5f5d 405 TIGRFAM TIGR04010 WcaD: putative colanic acid polymerase WcaD 1 404 6.4E-264 T 10-03-2017 IPR024013 Colanic acid biosynthesis, putative colanic acid polymerase, WcaD RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 Gene3D G3DSA:3.40.190.10 180 258 2.4E-17 T 10-03-2017 RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.1E-21 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 SUPERFAMILY SSF53850 93 295 6.05E-42 T 10-03-2017 RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 Gene3D G3DSA:1.10.10.10 2 88 2.0E-28 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 SUPERFAMILY SSF46785 3 87 4.75E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 Gene3D G3DSA:3.40.190.10 94 179 7.7E-37 T 10-03-2017 RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 Pfam PF03466 LysR substrate binding domain 91 292 5.5E-42 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.4E-10 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.4E-10 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS21005 b264c05bcf652e64087840e0bcf76319 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.4E-10 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS13275 2570cb8316ae4b95c2b5d701a994e9e2 444 PIRSF PIRSF006060 2 441 5.2E-49 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS13275 2570cb8316ae4b95c2b5d701a994e9e2 444 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 2 443 4.9E-147 T 10-03-2017 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 RG49_RS13275 2570cb8316ae4b95c2b5d701a994e9e2 444 Pfam PF13520 Amino acid permease 7 416 1.7E-37 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS13225 6c9c9d22d41a1db8e5067dde80431b02 158 Pfam PF04186 FxsA cytoplasmic membrane protein 8 109 2.7E-33 T 10-03-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 RG49_RS06670 5842a5028a21347c65b235a03d551b39 216 Pfam PF05944 Phage small terminase subunit 35 163 1.8E-44 T 10-03-2017 IPR010270 Bacteriophage P2, GpM GO:0003677|GO:0004519|GO:0019069 RG49_RS06030 21bd1ac51cf61c7416d9bff6ef4be505 179 Gene3D G3DSA:2.60.40.1090 30 178 1.5E-31 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS06030 21bd1ac51cf61c7416d9bff6ef4be505 179 SUPERFAMILY SSF49401 32 178 5.97E-28 T 10-03-2017 IPR008966 Adhesion domain RG49_RS06030 21bd1ac51cf61c7416d9bff6ef4be505 179 Pfam PF00419 Fimbrial protein 33 178 8.7E-14 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12135 3a20811860fd83fc5985fe52fc54224b 245 Gene3D G3DSA:3.40.50.300 51 222 4.5E-34 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12135 3a20811860fd83fc5985fe52fc54224b 245 Pfam PF01695 IstB-like ATP binding protein 93 218 1.6E-17 T 10-03-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 RG49_RS12135 3a20811860fd83fc5985fe52fc54224b 245 PIRSF PIRSF003073 1 245 1.0E-35 T 10-03-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein RG49_RS12135 3a20811860fd83fc5985fe52fc54224b 245 SMART SM00382 98 227 2.3E-5 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS12135 3a20811860fd83fc5985fe52fc54224b 245 SUPERFAMILY SSF52540 64 226 7.04E-22 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17845 b10c088164418700fd647512829d2829 183 Pfam PF02525 Flavodoxin-like fold 6 171 2.8E-39 T 10-03-2017 IPR003680 Flavodoxin-like fold RG49_RS17845 b10c088164418700fd647512829d2829 183 Hamap MF_01415 Glutathione-regulated potassium-efflux system ancillary protein KefG [kefG]. 1 182 48.312 T 10-03-2017 IPR023947 Glutathione-regulated potassium-efflux system ancillary protein KefG GO:0006813 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 RG49_RS17845 b10c088164418700fd647512829d2829 183 Gene3D G3DSA:3.40.50.360 6 176 2.8E-45 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS17845 b10c088164418700fd647512829d2829 183 SUPERFAMILY SSF52218 5 176 1.4E-45 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS03625 540cb9b909ae7f44431d81bfeb886a44 71 PIRSF PIRSF030786 1 71 8.7E-46 T 10-03-2017 IPR007054 Lysis protein S RG49_RS03625 540cb9b909ae7f44431d81bfeb886a44 71 Pfam PF04971 Bacteriophage P21 holin S 4 71 1.2E-48 T 10-03-2017 IPR007054 Lysis protein S RG49_RS07340 90744e2fc74900a7418e43396073931e 173 Pfam PF00691 OmpA family 72 167 4.7E-22 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS07340 90744e2fc74900a7418e43396073931e 173 ProSitePatterns PS01068 OmpA-like domain. 105 149 - T 10-03-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 RG49_RS07340 90744e2fc74900a7418e43396073931e 173 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 71 173 1.4E-46 T 10-03-2017 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 RG49_RS07340 90744e2fc74900a7418e43396073931e 173 Gene3D G3DSA:3.30.1330.60 68 172 9.6E-35 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS07340 90744e2fc74900a7418e43396073931e 173 SUPERFAMILY SSF103088 60 172 2.09E-34 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS07340 90744e2fc74900a7418e43396073931e 173 PRINTS PR01021 OMPA domain signature 73 95 2.4E-17 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS07340 90744e2fc74900a7418e43396073931e 173 PRINTS PR01021 OMPA domain signature 118 134 2.4E-17 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS07340 90744e2fc74900a7418e43396073931e 173 PRINTS PR01021 OMPA domain signature 103 118 2.4E-17 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS03615 5adca40c99812010c36428f81f298fb7 154 Pfam PF03245 Bacteriophage Rz lysis protein 30 153 3.2E-49 T 10-03-2017 IPR004929 Bacteriophage Rz lysis protein GO:0019076|GO:0019835 RG49_RS18080 56aa23d4e137982cf428a6ee5372d2cc 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 26.115 T 10-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18080 56aa23d4e137982cf428a6ee5372d2cc 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 7.5E-44 T 10-03-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18080 56aa23d4e137982cf428a6ee5372d2cc 117 Gene3D G3DSA:3.30.420.100 24 117 6.9E-37 T 10-03-2017 RG49_RS18080 56aa23d4e137982cf428a6ee5372d2cc 117 SUPERFAMILY SSF53137 3 115 5.45E-54 T 10-03-2017 RG49_RS18080 56aa23d4e137982cf428a6ee5372d2cc 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 2.9E-47 T 10-03-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS11195 0c4b65c44498a22741210287e17540e2 126 Pfam PF02261 Aspartate decarboxylase 1 114 2.5E-47 T 10-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 RG49_RS11195 0c4b65c44498a22741210287e17540e2 126 Gene3D G3DSA:2.40.40.20 1 124 6.7E-56 T 10-03-2017 RG49_RS11195 0c4b65c44498a22741210287e17540e2 126 SUPERFAMILY SSF50692 1 121 7.95E-48 T 10-03-2017 IPR009010 Aspartate decarboxylase-like domain RG49_RS11195 0c4b65c44498a22741210287e17540e2 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 5.5E-69 T 10-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 RG49_RS11195 0c4b65c44498a22741210287e17540e2 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 71.341 T 10-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 RG49_RS11195 0c4b65c44498a22741210287e17540e2 126 PIRSF PIRSF006246 1 125 9.6E-51 T 10-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 RG49_RS11195 0c4b65c44498a22741210287e17540e2 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 2.0E-66 T 10-03-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 Pfam PF02378 Phosphotransferase system, EIIC 113 405 1.7E-31 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 164 448 8.9E-88 T 10-03-2017 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 31 112 8.3E-21 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 SUPERFAMILY SSF55604 11 81 3.92E-18 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 22 39 - T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 Pfam PF00367 phosphotransferase system, EIIB 13 40 1.1E-10 T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 8 461 1.7E-223 T 10-03-2017 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 RG49_RS12690 9c99fd0318ea3b6e7dc22ff4565d79f9 473 Gene3D G3DSA:3.30.1360.60 8 83 2.4E-21 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS08210 786c1042684c5244e90cd312b3af7734 72 Gene3D G3DSA:3.90.820.10 12 70 1.4E-22 T 10-03-2017 RG49_RS08210 786c1042684c5244e90cd312b3af7734 72 Pfam PF03621 MbtH-like protein 4 54 8.7E-21 T 10-03-2017 IPR005153 MbtH-like protein RG49_RS08210 786c1042684c5244e90cd312b3af7734 72 SMART SM00923 5 55 4.8E-23 T 10-03-2017 IPR005153 MbtH-like protein RG49_RS08210 786c1042684c5244e90cd312b3af7734 72 SUPERFAMILY SSF160582 3 70 9.81E-24 T 10-03-2017 RG49_RS23405 ed490404c098c35887c971da41b6ab01 162 Pfam PF00419 Fimbrial protein 24 162 2.3E-16 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS23405 ed490404c098c35887c971da41b6ab01 162 Gene3D G3DSA:2.60.40.1090 22 162 4.8E-10 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS23405 ed490404c098c35887c971da41b6ab01 162 SUPERFAMILY SSF49401 32 162 1.04E-19 T 10-03-2017 IPR008966 Adhesion domain RG49_RS01695 5bce315e3194c261ae740ec3f215e13f 534 Gene3D G3DSA:3.40.50.720 2 87 2.9E-26 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01695 5bce315e3194c261ae740ec3f215e13f 534 Gene3D G3DSA:3.40.50.720 136 221 2.9E-26 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01695 5bce315e3194c261ae740ec3f215e13f 534 SUPERFAMILY SSF51905 1 269 2.98E-16 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS01695 5bce315e3194c261ae740ec3f215e13f 534 Pfam PF13454 FAD-NAD(P)-binding 5 164 7.7E-30 T 10-03-2017 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 1.3E-43 T 10-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 10-03-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 SUPERFAMILY SSF110324 2 81 5.58E-34 T 10-03-2017 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 1.0E-18 T 10-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.952 T 10-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.9E-38 T 10-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.9E-38 T 10-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.9E-38 T 10-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 Gene3D G3DSA:2.40.50.100 20 82 8.0E-32 T 10-03-2017 RG49_RS18715 f2a48cf62f93cb72e86a7a3f4e4c92ad 85 Pfam PF01016 Ribosomal L27 protein 2 82 6.3E-39 T 10-03-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS17255 37921dab3e2edc0b45927b528e3c125e 222 SMART SM00382 27 214 2.6E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17255 37921dab3e2edc0b45927b528e3c125e 222 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17255 37921dab3e2edc0b45927b528e3c125e 222 Pfam PF00005 ABC transporter 18 165 1.6E-37 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17255 37921dab3e2edc0b45927b528e3c125e 222 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 6.3E-94 T 10-03-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 RG49_RS17255 37921dab3e2edc0b45927b528e3c125e 222 SUPERFAMILY SSF52540 1 216 1.86E-67 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17255 37921dab3e2edc0b45927b528e3c125e 222 Gene3D G3DSA:3.40.50.300 1 215 8.9E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 350 357 - T 10-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 498 41.561 T 10-03-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 PRINTS PR00481 Cytosol aminopeptidase signature 287 308 6.0E-54 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 PRINTS PR00481 Cytosol aminopeptidase signature 374 389 6.0E-54 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 PRINTS PR00481 Cytosol aminopeptidase signature 324 345 6.0E-54 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 PRINTS PR00481 Cytosol aminopeptidase signature 346 366 6.0E-54 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 PRINTS PR00481 Cytosol aminopeptidase signature 265 282 6.0E-54 T 10-03-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 489 6.7E-120 T 10-03-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 1.4E-33 T 10-03-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 SUPERFAMILY SSF53187 180 496 5.65E-126 T 10-03-2017 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 SUPERFAMILY SSF52949 1 184 5.89E-52 T 10-03-2017 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 Gene3D G3DSA:3.40.630.10 171 496 1.6E-139 T 10-03-2017 RG49_RS12590 265d817054fc93eac46c9c4d888ed0e2 503 Gene3D G3DSA:3.40.220.10 1 161 1.5E-66 T 10-03-2017 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 2.4E-9 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 2.4E-9 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 2.4E-9 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 56 2.4E-9 T 10-03-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 10-03-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Gene3D G3DSA:2.40.240.10 348 461 1.1E-49 T 10-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 528 2.4E-63 T 10-03-2017 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 549 53.947 T 10-03-2017 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 SUPERFAMILY SSF50715 340 547 6.8E-81 T 10-03-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 551 0.0 T 10-03-2017 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Gene3D G3DSA:3.40.50.620 27 96 4.1E-43 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Gene3D G3DSA:3.40.50.620 212 262 4.1E-43 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Gene3D G3DSA:2.40.240.10 462 547 4.6E-35 T 10-03-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 SUPERFAMILY SSF52374 10 337 1.77E-103 T 10-03-2017 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Gene3D G3DSA:3.90.800.10 101 209 2.4E-48 T 10-03-2017 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 2.1E-128 T 10-03-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 RG49_RS07710 fde8f8b6cc11b1c3ee29baf3aac96d3e 554 Gene3D G3DSA:1.10.1160.10 263 338 6.2E-39 T 10-03-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 RG49_RS09105 6c24b5c8dd2910015562bbc01843a363 356 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 47.721 T 10-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 RG49_RS09105 6c24b5c8dd2910015562bbc01843a363 356 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 344 1.9E-171 T 10-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 RG49_RS09105 6c24b5c8dd2910015562bbc01843a363 356 Gene3D G3DSA:2.40.10.240 64 142 1.7E-18 T 10-03-2017 RG49_RS09105 6c24b5c8dd2910015562bbc01843a363 356 Gene3D G3DSA:3.40.1780.10 1 62 2.8E-101 T 10-03-2017 RG49_RS09105 6c24b5c8dd2910015562bbc01843a363 356 Gene3D G3DSA:3.40.1780.10 179 344 2.8E-101 T 10-03-2017 RG49_RS09105 6c24b5c8dd2910015562bbc01843a363 356 Pfam PF02547 Queuosine biosynthesis protein 4 343 5.1E-133 T 10-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 RG49_RS09105 6c24b5c8dd2910015562bbc01843a363 356 SUPERFAMILY SSF111337 1 343 6.28E-139 T 10-03-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 RG49_RS17825 7033524c6835105f1e9a884500a6b723 72 Hamap MF_00690 UPF0270 protein YheU [yheU]. 1 70 26.528 T 10-03-2017 IPR010648 Uncharacterised protein family UPF0270 RG49_RS17825 7033524c6835105f1e9a884500a6b723 72 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 67 6.0E-30 T 10-03-2017 IPR010648 Uncharacterised protein family UPF0270 RG49_RS17825 7033524c6835105f1e9a884500a6b723 72 SUPERFAMILY SSF118001 1 71 1.07E-29 T 10-03-2017 IPR010648 Uncharacterised protein family UPF0270 RG49_RS17825 7033524c6835105f1e9a884500a6b723 72 PIRSF PIRSF006169 1 72 6.5E-38 T 10-03-2017 IPR010648 Uncharacterised protein family UPF0270 RG49_RS17825 7033524c6835105f1e9a884500a6b723 72 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 69 5.0E-36 T 10-03-2017 IPR010648 Uncharacterised protein family UPF0270 RG49_RS17825 7033524c6835105f1e9a884500a6b723 72 Gene3D G3DSA:1.10.10.610 1 72 6.9E-39 T 10-03-2017 IPR010648 Uncharacterised protein family UPF0270 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 Gene3D G3DSA:2.40.30.110 278 361 4.5E-30 T 10-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 SUPERFAMILY SSF103025 3 277 1.26E-89 T 10-03-2017 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 359 5.0E-171 T 10-03-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 262 353 8.5E-18 T 10-03-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 359 44.89 T 10-03-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 Gene3D G3DSA:3.30.70.1400 54 137 8.3E-32 T 10-03-2017 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 SUPERFAMILY SSF101790 271 361 2.78E-26 T 10-03-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 PIRSF PIRSF006487 1 363 3.0E-79 T 10-03-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 Gene3D G3DSA:3.30.1360.120 144 231 2.6E-52 T 10-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 Gene3D G3DSA:3.30.1360.120 3 53 2.6E-52 T 10-03-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 RG49_RS20380 84044b10cc38bdc6b5a13d1ae107b0b9 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 254 6.5E-83 T 10-03-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal RG49_RS00460 708a2a923a341b281f59fe2d83d422c9 295 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 10-03-2017 IPR000540 Flagellar motor protein MotA, conserved site RG49_RS00460 708a2a923a341b281f59fe2d83d422c9 295 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 281 1.4E-115 T 10-03-2017 IPR022522 Flagellar motor stator, MotA RG49_RS00460 708a2a923a341b281f59fe2d83d422c9 295 Pfam PF01618 MotA/TolQ/ExbB proton channel family 140 239 4.1E-11 T 10-03-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 RG49_RS11410 80169ac40b04644e64f19b23f346f32f 414 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 359 383 - T 10-03-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 RG49_RS11410 80169ac40b04644e64f19b23f346f32f 414 Pfam PF01098 Cell cycle protein 47 402 4.1E-131 T 10-03-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 RG49_RS11410 80169ac40b04644e64f19b23f346f32f 414 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 45 400 1.6E-134 T 10-03-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 RG49_RS11410 80169ac40b04644e64f19b23f346f32f 414 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 43 410 42.309 T 10-03-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 RG49_RS13415 65d0114f477c44d7f15362a1990b1149 742 Pfam PF00350 Dynamin family 72 277 8.0E-18 T 10-03-2017 IPR022812 Dynamin superfamily RG49_RS13415 65d0114f477c44d7f15362a1990b1149 742 Gene3D G3DSA:3.40.50.300 207 320 1.1E-21 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13415 65d0114f477c44d7f15362a1990b1149 742 Gene3D G3DSA:3.40.50.300 69 169 1.1E-21 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13415 65d0114f477c44d7f15362a1990b1149 742 SUPERFAMILY SSF52540 207 348 4.12E-30 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13415 65d0114f477c44d7f15362a1990b1149 742 SUPERFAMILY SSF52540 57 169 4.12E-30 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 SUPERFAMILY SSF51735 48 293 6.62E-74 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 Gene3D G3DSA:3.40.50.720 45 292 3.0E-75 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 199 218 6.2E-5 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 138 6.2E-5 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 187 6.2E-5 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 186 214 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 138 3.9E-32 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 51 68 3.9E-32 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 218 3.9E-32 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 255 275 3.9E-32 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 237 3.9E-32 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 189 3.9E-32 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS19740 71b366fee434d27c10f65222f4cb5ea6 294 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 59 291 5.8E-58 T 10-03-2017 RG49_RS19615 7430480ec15e900068ef45baa7e99ad3 110 ProDom PD072223 MEMBRANE INNER YGIZ TRANSMEMBRANE 3 109 2.0E-47 T 10-03-2017 RG49_RS19615 7430480ec15e900068ef45baa7e99ad3 110 Pfam PF10840 Protein of unknown function (DUF2645) 13 109 2.5E-10 T 10-03-2017 IPR022553 Protein of unknown function DUF2645 RG49_RS03315 702375b166e5701885362211213db51b 49 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 47 5.8E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS03315 702375b166e5701885362211213db51b 49 PRINTS PR00281 Hok/Gef cell toxic protein family signature 5 23 5.8E-13 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS03315 702375b166e5701885362211213db51b 49 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 10 29 - T 10-03-2017 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 RG49_RS03315 702375b166e5701885362211213db51b 49 Pfam PF01848 Hok/gef family 6 46 7.0E-21 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS03315 702375b166e5701885362211213db51b 49 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 1 49 3.0E-10 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS12805 a91894fa7924894b5b81c91f75f2e59f 246 Gene3D G3DSA:3.30.540.10 1 147 1.1E-44 T 10-03-2017 RG49_RS12805 a91894fa7924894b5b81c91f75f2e59f 246 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 1 244 1.5E-113 T 10-03-2017 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 RG49_RS12805 a91894fa7924894b5b81c91f75f2e59f 246 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 10-03-2017 IPR020583 Inositol monophosphatase, metal-binding site RG49_RS12805 a91894fa7924894b5b81c91f75f2e59f 246 Gene3D G3DSA:3.40.190.80 148 243 1.5E-41 T 10-03-2017 RG49_RS12805 a91894fa7924894b5b81c91f75f2e59f 246 SUPERFAMILY SSF56655 1 243 2.75E-76 T 10-03-2017 RG49_RS12805 a91894fa7924894b5b81c91f75f2e59f 246 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 204 218 - T 10-03-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 RG49_RS12805 a91894fa7924894b5b81c91f75f2e59f 246 Pfam PF00459 Inositol monophosphatase family 5 233 4.3E-49 T 10-03-2017 IPR000760 Inositol monophosphatase GO:0046854 RG49_RS14465 ca63a4328404c8e6cbec8523b84f1d95 176 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 172 4.5E-87 T 10-03-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 RG49_RS14465 ca63a4328404c8e6cbec8523b84f1d95 176 SUPERFAMILY SSF56235 2 172 1.08E-58 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS14465 ca63a4328404c8e6cbec8523b84f1d95 176 Pfam PF00227 Proteasome subunit 2 167 1.3E-23 T 10-03-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 RG49_RS14465 ca63a4328404c8e6cbec8523b84f1d95 176 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 42.149 T 10-03-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 RG49_RS14465 ca63a4328404c8e6cbec8523b84f1d95 176 Gene3D G3DSA:3.60.20.10 2 172 3.7E-85 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS14465 ca63a4328404c8e6cbec8523b84f1d95 176 PIRSF PIRSF039093 1 175 3.1E-88 T 10-03-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 RG49_RS12075 1afa2acc67f30a08524474e757dffcb3 343 SUPERFAMILY SSF53335 154 315 1.02E-32 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS12075 1afa2acc67f30a08524474e757dffcb3 343 Pfam PF08468 Methyltransferase small domain N-terminal 8 162 6.0E-57 T 10-03-2017 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS12075 1afa2acc67f30a08524474e757dffcb3 343 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 4 336 45.877 T 10-03-2017 IPR023543 rRNA small subunit methyltransferase C GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS12075 1afa2acc67f30a08524474e757dffcb3 343 Pfam PF05175 Methyltransferase small domain 167 333 4.1E-61 T 10-03-2017 IPR007848 Methyltransferase small domain GO:0008168 RG49_RS12075 1afa2acc67f30a08524474e757dffcb3 343 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 265 271 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS12075 1afa2acc67f30a08524474e757dffcb3 343 Gene3D G3DSA:3.40.50.150 159 332 8.1E-29 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS04420 fdac5ebd57f1155340d7ac31bae488cd 137 PIRSF PIRSF002096 1 135 4.2E-58 T 10-03-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 RG49_RS04420 fdac5ebd57f1155340d7ac31bae488cd 137 Pfam PF00816 H-NS histone family 32 127 1.4E-20 T 10-03-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 RG49_RS04420 fdac5ebd57f1155340d7ac31bae488cd 137 Gene3D G3DSA:1.10.287.1050 1 58 4.4E-32 T 10-03-2017 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 RG49_RS04420 fdac5ebd57f1155340d7ac31bae488cd 137 SMART SM00528 87 135 1.0E-26 T 10-03-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 RG49_RS04420 fdac5ebd57f1155340d7ac31bae488cd 137 SUPERFAMILY SSF81273 2 58 5.1E-18 T 10-03-2017 RG49_RS04420 fdac5ebd57f1155340d7ac31bae488cd 137 Gene3D G3DSA:4.10.430.10 91 136 6.3E-27 T 10-03-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 RG49_RS04420 fdac5ebd57f1155340d7ac31bae488cd 137 SUPERFAMILY SSF81273 93 136 1.02E-12 T 10-03-2017 RG49_RS17025 3b0fb4d862f55919da7d85a871902311 141 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 8.8E-41 T 10-03-2017 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 RG49_RS17025 3b0fb4d862f55919da7d85a871902311 141 Pfam PF03960 ArsC family 7 115 9.8E-20 T 10-03-2017 IPR006660 Arsenate reductase-like RG49_RS17025 3b0fb4d862f55919da7d85a871902311 141 Gene3D G3DSA:3.40.30.10 1 140 8.8E-63 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS17025 3b0fb4d862f55919da7d85a871902311 141 SUPERFAMILY SSF52833 3 137 4.1E-39 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS24275 f49f9ea811d89e701c0cc9d9a464363a 188 Gene3D G3DSA:3.90.1720.10 68 186 7.4E-46 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS24275 f49f9ea811d89e701c0cc9d9a464363a 188 SUPERFAMILY SSF54001 67 185 1.86E-41 T 10-03-2017 RG49_RS24275 f49f9ea811d89e701c0cc9d9a464363a 188 Pfam PF00877 NlpC/P60 family 79 183 2.0E-34 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS07985 4fe26920311a303d77e7884ce9d76c3d 262 SUPERFAMILY SSF56317 1 254 1.83E-57 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS07985 4fe26920311a303d77e7884ce9d76c3d 262 Pfam PF00795 Carbon-nitrogen hydrolase 3 245 1.3E-37 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS07985 4fe26920311a303d77e7884ce9d76c3d 262 Gene3D G3DSA:3.60.110.10 2 256 1.3E-62 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS07985 4fe26920311a303d77e7884ce9d76c3d 262 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 10-03-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site RG49_RS14980 9d7cacf25e6bf152f5cf75cd6bcaff38 497 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 9 458 1.7E-191 T 10-03-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 RG49_RS14980 9d7cacf25e6bf152f5cf75cd6bcaff38 497 SUPERFAMILY SSF143968 326 489 3.4E-66 T 10-03-2017 RG49_RS14980 9d7cacf25e6bf152f5cf75cd6bcaff38 497 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 4 490 73.603 T 10-03-2017 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 RG49_RS14980 9d7cacf25e6bf152f5cf75cd6bcaff38 497 Gene3D G3DSA:1.20.5.570 458 497 7.7E-23 T 10-03-2017 RG49_RS14980 9d7cacf25e6bf152f5cf75cd6bcaff38 497 Gene3D G3DSA:3.40.1670.10 340 457 1.7E-55 T 10-03-2017 RG49_RS14980 9d7cacf25e6bf152f5cf75cd6bcaff38 497 SUPERFAMILY SSF50475 6 325 2.43E-128 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS14980 9d7cacf25e6bf152f5cf75cd6bcaff38 497 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 14 434 5.7E-172 T 10-03-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 RG49_RS11585 b0bfe46f5f02d0b5a7a1b5d90cdce735 219 Pfam PF00849 RNA pseudouridylate synthase 22 169 5.4E-30 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS11585 b0bfe46f5f02d0b5a7a1b5d90cdce735 219 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 7 218 2.5E-61 T 10-03-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS11585 b0bfe46f5f02d0b5a7a1b5d90cdce735 219 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 60 74 - T 10-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS11585 b0bfe46f5f02d0b5a7a1b5d90cdce735 219 SUPERFAMILY SSF55120 8 216 1.38E-63 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS13375 f52ef634ecd02f6a92ea8959834dcae0 253 SMART SM00342 162 244 5.4E-28 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13375 f52ef634ecd02f6a92ea8959834dcae0 253 Gene3D G3DSA:1.10.10.60 197 247 6.7E-13 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13375 f52ef634ecd02f6a92ea8959834dcae0 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 213 228 3.7E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS13375 f52ef634ecd02f6a92ea8959834dcae0 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 244 3.7E-6 T 10-03-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 RG49_RS13375 f52ef634ecd02f6a92ea8959834dcae0 253 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 198 240 - T 10-03-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 RG49_RS13375 f52ef634ecd02f6a92ea8959834dcae0 253 Pfam PF12833 Helix-turn-helix domain 169 244 1.1E-13 T 10-03-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 RG49_RS13375 f52ef634ecd02f6a92ea8959834dcae0 253 SUPERFAMILY SSF46689 197 248 2.69E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS13470 27dbaefd1a7fe6d4e26f5b326c260b59 150 Pfam PF06754 Phosphonate metabolism protein PhnG 7 147 1.8E-52 T 10-03-2017 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 RG49_RS13470 27dbaefd1a7fe6d4e26f5b326c260b59 150 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 6 148 5.4E-54 T 10-03-2017 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 RG49_RS11940 1129ce31eceb1fd2c2e696746fb9ebd9 108 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 10 101 1.0E-40 T 10-03-2017 IPR013335 Trp repressor, bacterial GO:0006355 RG49_RS11940 1129ce31eceb1fd2c2e696746fb9ebd9 108 PIRSF PIRSF003196 3 108 1.3E-40 T 10-03-2017 IPR013335 Trp repressor, bacterial GO:0006355 RG49_RS11940 1129ce31eceb1fd2c2e696746fb9ebd9 108 SUPERFAMILY SSF48295 5 105 7.85E-30 T 10-03-2017 IPR010921 Trp repressor/replication initiator GO:0043565 RG49_RS11940 1129ce31eceb1fd2c2e696746fb9ebd9 108 Gene3D G3DSA:1.10.1270.10 10 107 1.5E-46 T 10-03-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 RG49_RS11940 1129ce31eceb1fd2c2e696746fb9ebd9 108 TIGRFAM TIGR01321 TrpR: trp operon repressor 11 104 7.1E-43 T 10-03-2017 IPR013335 Trp repressor, bacterial GO:0006355 RG49_RS11940 1129ce31eceb1fd2c2e696746fb9ebd9 108 Pfam PF01371 Trp repressor protein 17 102 2.1E-28 T 10-03-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 RG49_RS11940 1129ce31eceb1fd2c2e696746fb9ebd9 108 Hamap MF_00475 Trp operon repressor [trpR]. 15 108 24.11 T 10-03-2017 IPR013335 Trp repressor, bacterial GO:0006355 RG49_RS16300 c06eb074ad8381e36e1846f5c56d7b2c 348 Gene3D G3DSA:3.40.50.2000 168 344 3.3E-55 T 10-03-2017 RG49_RS16300 c06eb074ad8381e36e1846f5c56d7b2c 348 Gene3D G3DSA:3.40.50.2000 1 147 3.8E-59 T 10-03-2017 RG49_RS16300 c06eb074ad8381e36e1846f5c56d7b2c 348 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 69 324 2.9E-91 T 10-03-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 RG49_RS16300 c06eb074ad8381e36e1846f5c56d7b2c 348 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 2 343 8.7E-172 T 10-03-2017 IPR011910 Lipopolysaccharide heptosyltransferase II GO:0009103|GO:0016757 RG49_RS16300 c06eb074ad8381e36e1846f5c56d7b2c 348 SUPERFAMILY SSF53756 1 343 7.33E-102 T 10-03-2017 RG49_RS06740 d8a1bef9dae1e923602644fa79e013bc 113 ProDom PD073252 TRANSPOSABLE STY4640 FELS-2 RETRON ORFC C0938 ELEMENT STY3664 EC67 PHAGE-RELATED 1 111 8.0E-57 T 10-03-2017 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 Gene3D G3DSA:3.40.1390.20 226 366 2.8E-30 T 10-03-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like RG49_RS23595 225a85521704861f41a38bb404b2c028 714 Gene3D G3DSA:3.40.50.300 3 224 1.8E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23595 225a85521704861f41a38bb404b2c028 714 Pfam PF13500 AAA domain 5 230 1.8E-47 T 10-03-2017 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 PIRSF PIRSF006107 1 714 0.0 T 10-03-2017 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 Gene3D G3DSA:3.40.50.10750 525 683 1.0E-67 T 10-03-2017 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 407 707 5.6E-139 T 10-03-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 Pfam PF07085 DRTGG domain 234 345 1.8E-29 T 10-03-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 SUPERFAMILY SSF52540 4 241 1.22E-28 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23595 225a85521704861f41a38bb404b2c028 714 Pfam PF01515 Phosphate acetyl/butaryl transferase 392 707 3.7E-129 T 10-03-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 SUPERFAMILY SSF53659 393 711 1.77E-94 T 10-03-2017 RG49_RS23595 225a85521704861f41a38bb404b2c028 714 SUPERFAMILY SSF75138 230 354 2.75E-25 T 10-03-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like RG49_RS17735 ea34d666ba0a071439a52dc6006a78a9 340 Gene3D G3DSA:3.40.50.10490 22 186 1.3E-19 T 10-03-2017 RG49_RS17735 ea34d666ba0a071439a52dc6006a78a9 340 SUPERFAMILY SSF53697 16 338 1.14E-55 T 10-03-2017 RG49_RS17735 ea34d666ba0a071439a52dc6006a78a9 340 Pfam PF01380 SIS domain 44 164 1.3E-7 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS17735 ea34d666ba0a071439a52dc6006a78a9 340 Gene3D G3DSA:3.40.50.10490 187 332 1.6E-18 T 10-03-2017 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 ProSitePatterns PS01134 FtsZ protein signature 1. 43 77 - T 10-03-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 SMART SM00865 206 324 3.4E-56 T 10-03-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 Gene3D G3DSA:3.30.1330.20 214 321 4.3E-47 T 10-03-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 Gene3D G3DSA:3.40.50.1440 13 213 2.5E-93 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 8 343 38.188 T 10-03-2017 IPR000158 Cell division protein FtsZ GO:0005525 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 PRINTS PR00423 Cell division protein FtsZ signature 188 210 2.5E-52 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 PRINTS PR00423 Cell division protein FtsZ signature 97 117 2.5E-52 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 PRINTS PR00423 Cell division protein FtsZ signature 211 232 2.5E-52 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 PRINTS PR00423 Cell division protein FtsZ signature 125 146 2.5E-52 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 SMART SM00864 12 204 3.3E-111 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 172 1.9E-42 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 SUPERFAMILY SSF55307 203 319 7.33E-43 T 10-03-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 Pfam PF12327 FtsZ family, C-terminal domain 221 315 3.8E-37 T 10-03-2017 IPR024757 Cell division protein FtsZ, C-terminal RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 SUPERFAMILY SSF52490 12 207 1.7E-69 T 10-03-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 ProSitePatterns PS01135 FtsZ protein signature 2. 96 117 - T 10-03-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 RG49_RS11380 c16a16e243d432912840fefd5939be2e 383 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 338 4.5E-142 T 10-03-2017 IPR000158 Cell division protein FtsZ GO:0005525 RG49_RS25210 5d0164484283f93ddb11a60319df1742 321 Gene3D G3DSA:3.40.50.1360 67 321 2.0E-59 T 10-03-2017 RG49_RS25210 5d0164484283f93ddb11a60319df1742 321 Pfam PF04198 Putative sugar-binding domain 71 320 4.0E-52 T 10-03-2017 IPR007324 Sugar-binding domain, putative GO:0030246 RG49_RS25210 5d0164484283f93ddb11a60319df1742 321 SUPERFAMILY SSF100950 73 321 9.21E-54 T 10-03-2017 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 Gene3D G3DSA:3.30.1270.10 211 245 3.5E-42 T 10-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 Gene3D G3DSA:3.30.1270.10 82 134 3.5E-42 T 10-03-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 236 2.0E-107 T 10-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 Pfam PF01709 Transcriptional regulator 5 235 5.4E-94 T 10-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 Gene3D G3DSA:3.30.70.980 135 204 7.2E-31 T 10-03-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 238 36.72 T 10-03-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 SUPERFAMILY SSF75625 3 244 1.24E-97 T 10-03-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS00595 fbfddc817c4c3720caa0df1f266bcd50 246 Gene3D G3DSA:1.10.10.200 1 79 1.4E-34 T 10-03-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like RG49_RS10755 e888ecaef9e6ef34096c988cedfefcf2 207 SUPERFAMILY SSF53335 7 201 4.96E-35 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS10755 e888ecaef9e6ef34096c988cedfefcf2 207 Pfam PF08241 Methyltransferase domain 5 96 7.0E-22 T 10-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 RG49_RS10755 e888ecaef9e6ef34096c988cedfefcf2 207 Gene3D G3DSA:3.40.50.150 7 205 3.8E-37 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 SUPERFAMILY SSF51445 7 404 3.15E-88 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 Gene3D G3DSA:3.20.20.80 2 406 4.5E-69 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 SUPERFAMILY SSF51011 405 491 1.03E-29 T 10-03-2017 RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 PIRSF PIRSF001021 1 494 7.5E-209 T 10-03-2017 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 Gene3D G3DSA:2.60.40.1180 408 491 6.0E-31 T 10-03-2017 IPR013780 Glycosyl hydrolase, all-beta RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 416 491 6.4E-6 T 10-03-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 Pfam PF00128 Alpha amylase, catalytic domain 28 367 9.4E-21 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS00260 fe1b14c88eee1debee777c19c3f0e1eb 495 SMART SM00642 4 402 5.0E-60 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 1 409 39.192 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 Pfam PF01566 Natural resistance-associated macrophage protein 38 384 6.3E-127 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 299 318 1.3E-29 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 150 171 1.3E-29 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 97 123 1.3E-29 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 125 144 1.3E-29 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 200 223 1.3E-29 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS23180 c2e754c9a91b75c862fef2772e28db8c 412 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 19 377 3.3E-99 T 10-03-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 RG49_RS21490 06cb9b04c3aa4d6c8d9b3dba077c19c2 136 ProDom PD021295 MATURATION HYDROGENLYASE FORMATE HYCH LYASE HYCE PROCESSING OXIDOREDUCTASE J COMPONENT 1 134 4.0E-76 T 10-03-2017 IPR010005 Formate hydrogenlyase maturation HycH RG49_RS21490 06cb9b04c3aa4d6c8d9b3dba077c19c2 136 Pfam PF07450 Formate hydrogenlyase maturation protein HycH 4 133 8.9E-56 T 10-03-2017 IPR010005 Formate hydrogenlyase maturation HycH RG49_RS16710 f482944325ae85c7e9a4624ec771d036 96 SMART SM00530 37 91 9.5E-5 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS16710 f482944325ae85c7e9a4624ec771d036 96 Gene3D G3DSA:1.10.260.40 37 88 1.0E-11 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS16710 f482944325ae85c7e9a4624ec771d036 96 SUPERFAMILY SSF47413 38 82 3.22E-7 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS16710 f482944325ae85c7e9a4624ec771d036 96 Pfam PF01381 Helix-turn-helix 38 80 1.4E-5 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS23610 957393d58ba08f00c4dc8206d69808a0 151 Hamap MF_01101 UPF0208 membrane protein YfbV [yfbV]. 9 151 36.961 T 10-03-2017 IPR007334 Uncharacterised protein family UPF0208 RG49_RS23610 957393d58ba08f00c4dc8206d69808a0 151 Pfam PF04217 Protein of unknown function, DUF412 11 149 2.6E-57 T 10-03-2017 IPR007334 Uncharacterised protein family UPF0208 RG49_RS22935 548ebbc11ef0154a0be78c9ffc762231 166 Pfam PF00936 BMC domain 4 79 2.0E-21 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22935 548ebbc11ef0154a0be78c9ffc762231 166 SMART SM00877 3 79 1.4E-26 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22935 548ebbc11ef0154a0be78c9ffc762231 166 SUPERFAMILY SSF143414 3 95 8.63E-24 T 10-03-2017 RG49_RS22935 548ebbc11ef0154a0be78c9ffc762231 166 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 21 40 - T 10-03-2017 IPR020808 Bacterial microcompartments protein, conserved site RG49_RS22935 548ebbc11ef0154a0be78c9ffc762231 166 Pfam PF16365 Ethanolamine utilization protein EutK C-terminus 109 162 3.8E-35 T 10-03-2017 IPR032298 Ethanolamine utilization protein EutK, C-terminal RG49_RS22935 548ebbc11ef0154a0be78c9ffc762231 166 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 47 5.0E-9 T 10-03-2017 RG49_RS22935 548ebbc11ef0154a0be78c9ffc762231 166 Gene3D G3DSA:1.10.10.10 109 165 2.9E-7 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS14705 ed29993cf859e7bc56aba9437df4de6f 211 SUPERFAMILY SSF81342 4 205 9.28E-55 T 10-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 RG49_RS14705 ed29993cf859e7bc56aba9437df4de6f 211 Gene3D G3DSA:1.20.950.20 1 209 3.8E-71 T 10-03-2017 RG49_RS14705 ed29993cf859e7bc56aba9437df4de6f 211 Pfam PF01292 Prokaryotic cytochrome b561 9 184 3.3E-22 T 10-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 RG49_RS14705 ed29993cf859e7bc56aba9437df4de6f 211 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 7 204 3.5E-66 T 10-03-2017 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 RG49_RS08085 c43a041181261d5f8344bb6d01bcee7b 142 Pfam PF00582 Universal stress protein family 1 142 1.0E-27 T 10-03-2017 IPR006016 UspA GO:0006950 RG49_RS08085 c43a041181261d5f8344bb6d01bcee7b 142 PRINTS PR01438 Universal stress protein signature 120 142 1.9E-14 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS08085 c43a041181261d5f8344bb6d01bcee7b 142 PRINTS PR01438 Universal stress protein signature 2 20 1.9E-14 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS08085 c43a041181261d5f8344bb6d01bcee7b 142 PRINTS PR01438 Universal stress protein signature 103 115 1.9E-14 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS08085 c43a041181261d5f8344bb6d01bcee7b 142 SUPERFAMILY SSF52402 1 142 3.68E-27 T 10-03-2017 RG49_RS08085 c43a041181261d5f8344bb6d01bcee7b 142 Gene3D G3DSA:3.40.50.620 2 142 3.0E-29 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS04365 3db7a07166382e6825119a60c95a997b 337 Gene3D G3DSA:3.40.50.300 13 276 9.0E-74 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04365 3db7a07166382e6825119a60c95a997b 337 SMART SM00382 48 254 2.6E-14 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS04365 3db7a07166382e6825119a60c95a997b 337 Pfam PF00005 ABC transporter 40 196 5.7E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS04365 3db7a07166382e6825119a60c95a997b 337 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS04365 3db7a07166382e6825119a60c95a997b 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 312 2.1E-20 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS04365 3db7a07166382e6825119a60c95a997b 337 SUPERFAMILY SSF52540 49 316 4.77E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04365 3db7a07166382e6825119a60c95a997b 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 330 7.4E-25 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS23955 c85df4f0f034c51fe420ff314ef1d243 240 SUPERFAMILY SSF53335 17 224 2.84E-44 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS23955 c85df4f0f034c51fe420ff314ef1d243 240 Gene3D G3DSA:3.40.50.150 28 224 1.6E-45 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS23955 c85df4f0f034c51fe420ff314ef1d243 240 Pfam PF13489 Methyltransferase domain 57 170 4.2E-25 T 10-03-2017 RG49_RS23955 c85df4f0f034c51fe420ff314ef1d243 240 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 16 234 1.9E-91 T 10-03-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 RG49_RS23955 c85df4f0f034c51fe420ff314ef1d243 240 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 14 240 38.456 T 10-03-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 RG49_RS15340 f9de714674d1b64ac6831b260f357baa 93 Pfam PF13616 PPIC-type PPIASE domain 15 90 1.4E-20 T 10-03-2017 RG49_RS15340 f9de714674d1b64ac6831b260f357baa 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 31 51 - T 10-03-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 RG49_RS15340 f9de714674d1b64ac6831b260f357baa 93 Gene3D G3DSA:3.10.50.40 5 91 3.3E-34 T 10-03-2017 RG49_RS15340 f9de714674d1b64ac6831b260f357baa 93 SUPERFAMILY SSF54534 5 90 2.03E-28 T 10-03-2017 RG49_RS18550 8ac83ad509ec54e5dc677b8bdc2e6c61 254 Pfam PF06551 Protein of unknown function (DUF1120) 33 146 1.2E-43 T 10-03-2017 IPR010546 Protein of unknown function DUF1120 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 2.3E-24 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 SUPERFAMILY SSF52172 7 137 2.7E-34 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 SUPERFAMILY SSF46894 137 210 7.48E-22 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 Pfam PF00072 Response regulator receiver domain 9 121 5.2E-31 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 SMART SM00421 151 208 3.4E-24 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 Gene3D G3DSA:1.10.10.10 155 211 4.9E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 SMART SM00448 7 120 1.6E-33 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.7E-15 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.7E-15 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.7E-15 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS24175 157a1dffc1c88c9cf3998d3a1bc58475 215 Gene3D G3DSA:3.40.50.2300 6 154 2.4E-38 T 10-03-2017 RG49_RS23415 971f3a53c1506f86227a0e8ed47dbcd7 285 Pfam PF11245 Protein of unknown function (DUF2544) 47 283 1.3E-62 T 10-03-2017 IPR021407 Protein of unknown function DUF2544 RG49_RS01925 b2cdcea1d0c57fe6f0d34de0d283b551 71 SUPERFAMILY SSF68989 1 71 1.12E-22 T 10-03-2017 IPR007985 Haemolysin expression modulating, HHA RG49_RS01925 b2cdcea1d0c57fe6f0d34de0d283b551 71 Gene3D G3DSA:1.20.1280.40 1 71 2.0E-32 T 10-03-2017 IPR007985 Haemolysin expression modulating, HHA RG49_RS01925 b2cdcea1d0c57fe6f0d34de0d283b551 71 Pfam PF05321 Haemolysin expression modulating protein 8 68 2.7E-29 T 10-03-2017 IPR007985 Haemolysin expression modulating, HHA RG49_RS06255 0c42678a48843a5c27d22f9dd34c61f5 287 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 277 1.8E-117 T 10-03-2017 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 Pfam PF07690 Major Facilitator Superfamily 20 263 5.0E-33 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 SUPERFAMILY SSF103473 11 402 7.67E-71 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 Gene3D G3DSA:1.20.1250.20 13 199 2.1E-40 T 10-03-2017 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 Gene3D G3DSA:1.20.1250.20 210 399 1.3E-27 T 10-03-2017 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 PRINTS PR01035 Tetracycline resistance protein signature 348 371 9.9E-12 T 10-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 PRINTS PR01035 Tetracycline resistance protein signature 87 111 9.9E-12 T 10-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 PRINTS PR01035 Tetracycline resistance protein signature 114 135 9.9E-12 T 10-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 PRINTS PR01035 Tetracycline resistance protein signature 313 333 9.9E-12 T 10-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 PRINTS PR01035 Tetracycline resistance protein signature 25 41 9.9E-12 T 10-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 PRINTS PR01035 Tetracycline resistance protein signature 144 166 9.9E-12 T 10-03-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 RG49_RS05385 941f877beffd9bc430aa3e946905e822 408 Hamap MF_01528 Multidrug resistance protein MdtG [mdtG]. 3 406 49.348 T 10-03-2017 IPR023692 Multidrug resistance protein MdtG GO:0005215|GO:0005886 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 Pfam PF02839 Carbohydrate binding domain 461 510 2.3E-15 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SMART SM00495 229 277 8.4E-7 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SMART SM00495 25 73 1.7E-8 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SMART SM00495 527 569 22.0 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SMART SM00495 414 458 1.5E-6 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SMART SM00495 461 513 5.7E-13 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SMART SM00495 128 176 5.7E-6 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SMART SM00495 339 387 2.5E-8 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 Gene3D G3DSA:3.20.20.80 612 867 9.0E-12 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SUPERFAMILY SSF51445 608 879 1.01E-26 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 SUPERFAMILY SSF51055 458 515 3.66E-10 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS17915 9fac5c6693305ea6d4129095cb5dfaa8 899 Gene3D G3DSA:2.10.10.20 460 515 1.4E-12 T 10-03-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 RG49_RS07915 ab3a68cf5d9d169ee647f6b28ec18eca 203 Gene3D G3DSA:3.40.50.1240 1 195 2.1E-56 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS07915 ab3a68cf5d9d169ee647f6b28ec18eca 203 PIRSF PIRSF000709 1 185 4.1E-16 T 10-03-2017 RG49_RS07915 ab3a68cf5d9d169ee647f6b28ec18eca 203 SMART SM00855 2 156 9.4E-21 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS07915 ab3a68cf5d9d169ee647f6b28ec18eca 203 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 10-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 RG49_RS07915 ab3a68cf5d9d169ee647f6b28ec18eca 203 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 3 181 4.2E-60 T 10-03-2017 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 RG49_RS07915 ab3a68cf5d9d169ee647f6b28ec18eca 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 194 2.2E-54 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS07915 ab3a68cf5d9d169ee647f6b28ec18eca 203 SUPERFAMILY SSF53254 1 195 1.17E-56 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS12920 aff5c61142ffbf46acd61b3f3e5e4067 228 SUPERFAMILY SSF53639 2 219 4.71E-70 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS12920 aff5c61142ffbf46acd61b3f3e5e4067 228 SMART SM01007 6 194 1.2E-67 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS12920 aff5c61142ffbf46acd61b3f3e5e4067 228 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 193 2.1E-47 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS12920 aff5c61142ffbf46acd61b3f3e5e4067 228 Hamap MF_01952 L-ribulose-5-phosphate 4-epimerase UlaF [ulaF]. 1 228 65.247 T 10-03-2017 IPR023499 L-ribulose-5-phosphate 4-epimerase UlaF GO:0008742 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 RG49_RS12920 aff5c61142ffbf46acd61b3f3e5e4067 228 Gene3D G3DSA:3.40.225.10 2 227 3.1E-72 T 10-03-2017 IPR001303 Class II aldolase/adducin N-terminal RG49_RS02070 ba3dc74f48fa2edfcfa472ce207310d8 109 Pfam PF00893 Small Multidrug Resistance protein 6 99 4.0E-29 T 10-03-2017 IPR000390 Small multidrug resistance protein family GO:0016021 RG49_RS02070 ba3dc74f48fa2edfcfa472ce207310d8 109 Hamap MF_01597 Spermidine export protein MdtI [mdtI]. 1 109 34.9 T 10-03-2017 IPR023737 Spermidine export protein MdtI GO:0005886|GO:0015606|GO:0015848 RG49_RS02070 ba3dc74f48fa2edfcfa472ce207310d8 109 SUPERFAMILY SSF103481 12 108 2.09E-17 T 10-03-2017 RG49_RS03200 9c19ea7493ac852dc7ffe972904a7ab9 337 SMART SM00382 29 212 2.2E-17 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS03200 9c19ea7493ac852dc7ffe972904a7ab9 337 Pfam PF08402 TOBE domain 257 331 5.2E-17 T 10-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 RG49_RS03200 9c19ea7493ac852dc7ffe972904a7ab9 337 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS03200 9c19ea7493ac852dc7ffe972904a7ab9 337 SUPERFAMILY SSF52540 5 241 4.06E-83 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03200 9c19ea7493ac852dc7ffe972904a7ab9 337 Pfam PF00005 ABC transporter 21 162 7.4E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS03200 9c19ea7493ac852dc7ffe972904a7ab9 337 SUPERFAMILY SSF50331 240 328 7.37E-10 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS03200 9c19ea7493ac852dc7ffe972904a7ab9 337 Gene3D G3DSA:3.40.50.300 3 237 4.9E-76 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11765 7f88e457a3a03db7aed96b5239483b8d 381 Pfam PF00577 Outer membrane usher protein 2 298 5.4E-59 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS11765 7f88e457a3a03db7aed96b5239483b8d 381 Pfam PF13953 PapC C-terminal domain 308 369 3.9E-9 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS25065 e53cce12aeee9aedaad628645b139cb8 325 Gene3D G3DSA:3.30.1890.10 52 186 3.0E-59 T 10-03-2017 RG49_RS25065 e53cce12aeee9aedaad628645b139cb8 325 Gene3D G3DSA:3.30.1890.10 251 294 3.0E-59 T 10-03-2017 RG49_RS25065 e53cce12aeee9aedaad628645b139cb8 325 SUPERFAMILY SSF160355 54 292 2.35E-70 T 10-03-2017 RG49_RS25065 e53cce12aeee9aedaad628645b139cb8 325 Pfam PF02706 Chain length determinant protein 16 154 7.1E-19 T 10-03-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 SUPERFAMILY SSF81901 3 114 1.7E-29 T 10-03-2017 RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 Pfam PF08238 Sel1 repeat 3 33 3.2E-7 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 Pfam PF08238 Sel1 repeat 35 70 4.5E-11 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 Pfam PF08238 Sel1 repeat 71 104 8.4E-5 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 Gene3D G3DSA:1.25.40.10 3 116 1.7E-34 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 SMART SM00671 71 106 3.4E-7 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 SMART SM00671 1 34 0.0046 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07870 fb1aa89635b421985282c611c5e0840e 119 SMART SM00671 35 70 2.2E-12 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 Gene3D G3DSA:3.10.310.10 1 120 4.8E-50 T 10-03-2017 RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 Gene3D G3DSA:3.10.310.10 121 262 9.3E-53 T 10-03-2017 RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 Pfam PF01678 Diaminopimelate epimerase 3 123 6.2E-35 T 10-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 Pfam PF01678 Diaminopimelate epimerase 152 267 4.6E-35 T 10-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 273 6.5E-105 T 10-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 274 39.819 T 10-03-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 10-03-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 RG49_RS15145 8a2d9e50c5c8f8c6aa8d3d35d6818e19 274 SUPERFAMILY SSF54506 2 273 1.02E-56 T 10-03-2017 RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 SUPERFAMILY SSF81296 14 104 9.33E-8 T 10-03-2017 IPR014756 Immunoglobulin E-set RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 SMART SM00642 128 522 6.7E-90 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 SUPERFAMILY SSF51011 531 604 1.49E-9 T 10-03-2017 RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 2 105 2.7E-8 T 10-03-2017 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 PIRSF PIRSF036918 1 604 2.0E-246 T 10-03-2017 IPR017069 Maltodextrin glucosidase GO:0004558|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.20|KEGG: 00500+3.2.1.20|MetaCyc: PWY-842 RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 Pfam PF00128 Alpha amylase, catalytic domain 178 494 3.0E-88 T 10-03-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 Gene3D G3DSA:2.60.40.1180 526 569 6.3E-8 T 10-03-2017 IPR013780 Glycosyl hydrolase, all-beta RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 SUPERFAMILY SSF51445 118 531 1.63E-88 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS09115 1c1f4299f4de39a5ade1dffef6d6e95a 605 Gene3D G3DSA:3.20.20.80 118 523 1.9E-106 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS25005 5599cf1c2d95e6ffab57ec9b13b0743a 299 Gene3D G3DSA:3.90.25.10 221 283 1.4E-30 T 10-03-2017 RG49_RS25005 5599cf1c2d95e6ffab57ec9b13b0743a 299 Gene3D G3DSA:3.90.25.10 172 184 1.4E-30 T 10-03-2017 RG49_RS25005 5599cf1c2d95e6ffab57ec9b13b0743a 299 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 292 2.2E-98 T 10-03-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 RG49_RS25005 5599cf1c2d95e6ffab57ec9b13b0743a 299 Pfam PF04321 RmlD substrate binding domain 1 293 8.0E-109 T 10-03-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 RG49_RS25005 5599cf1c2d95e6ffab57ec9b13b0743a 299 Gene3D G3DSA:3.40.50.720 1 171 3.0E-29 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS25005 5599cf1c2d95e6ffab57ec9b13b0743a 299 SUPERFAMILY SSF51735 1 294 3.51E-103 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21060 43a98c026719d6e195371b7693d4d122 455 Gene3D G3DSA:3.30.1330.90 10 158 1.8E-55 T 10-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 RG49_RS21060 43a98c026719d6e195371b7693d4d122 455 Pfam PF03315 Serine dehydratase beta chain 3 155 1.4E-56 T 10-03-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 RG49_RS21060 43a98c026719d6e195371b7693d4d122 455 Pfam PF03313 Serine dehydratase alpha chain 184 448 1.5E-96 T 10-03-2017 IPR005130 Serine dehydratase-like, alpha subunit RG49_RS21060 43a98c026719d6e195371b7693d4d122 455 SUPERFAMILY SSF143548 16 158 4.97E-46 T 10-03-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 RG49_RS21060 43a98c026719d6e195371b7693d4d122 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 4.5E-223 T 10-03-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 SUPERFAMILY SSF53187 338 408 7.71E-83 T 10-03-2017 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 SUPERFAMILY SSF53187 6 221 7.71E-83 T 10-03-2017 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 Gene3D G3DSA:3.40.630.10 350 408 1.9E-98 T 10-03-2017 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 Gene3D G3DSA:3.40.630.10 5 224 1.9E-98 T 10-03-2017 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 Gene3D G3DSA:3.30.70.360 225 324 8.8E-40 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 TIGRFAM TIGR03176 AllC: allantoate amidohydrolase 1 411 1.3E-231 T 10-03-2017 IPR017591 Allantoate amidohydrolase GO:0000256|GO:0009442|GO:0030145|GO:0042803|GO:0047652 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 Pfam PF01546 Peptidase family M20/M25/M40 79 405 4.6E-32 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 7 407 2.4E-199 T 10-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 SUPERFAMILY SSF55031 212 328 3.49E-26 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS08495 ea0d6bc313bf389e37eaee4a2e55143a 411 PIRSF PIRSF001235 2 411 3.2E-132 T 10-03-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 RG49_RS11040 eecf6b755b9a9b4068715fd9ae59dc6f 207 Pfam PF03458 UPF0126 domain 92 163 6.3E-20 T 10-03-2017 IPR005115 Uncharacterised domain UPF0126 RG49_RS11040 eecf6b755b9a9b4068715fd9ae59dc6f 207 Pfam PF03458 UPF0126 domain 4 78 3.6E-23 T 10-03-2017 IPR005115 Uncharacterised domain UPF0126 RG49_RS18060 1a6377b3ef5b5fc6796affa39279224a 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 10-03-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18060 1a6377b3ef5b5fc6796affa39279224a 179 SUPERFAMILY SSF55282 4 179 2.35E-79 T 10-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18060 1a6377b3ef5b5fc6796affa39279224a 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 5.0E-41 T 10-03-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18060 1a6377b3ef5b5fc6796affa39279224a 179 Gene3D G3DSA:3.30.1440.10 2 179 7.2E-81 T 10-03-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18060 1a6377b3ef5b5fc6796affa39279224a 179 PIRSF PIRSF002161 1 179 1.5E-66 T 10-03-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18060 1a6377b3ef5b5fc6796affa39279224a 179 Pfam PF00281 Ribosomal protein L5 24 80 9.4E-29 T 10-03-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18060 1a6377b3ef5b5fc6796affa39279224a 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.826 T 10-03-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17425 838205352281ee3792f39070eaba1e18 477 Hamap MF_00484 Glycogen synthase [glgA]. 1 476 47.143 T 10-03-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 RG49_RS17425 838205352281ee3792f39070eaba1e18 477 Pfam PF08323 Starch synthase catalytic domain 2 233 1.3E-71 T 10-03-2017 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 RG49_RS17425 838205352281ee3792f39070eaba1e18 477 Gene3D G3DSA:3.40.50.2000 251 457 5.7E-70 T 10-03-2017 RG49_RS17425 838205352281ee3792f39070eaba1e18 477 SUPERFAMILY SSF53756 5 476 5.58E-117 T 10-03-2017 RG49_RS17425 838205352281ee3792f39070eaba1e18 477 Pfam PF00534 Glycosyl transferases group 1 288 438 1.9E-12 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS17425 838205352281ee3792f39070eaba1e18 477 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 475 1.7E-176 T 10-03-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 RG49_RS12110 5c387d6067b12d8574c994e0ad0ec72e 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 165 2.6E-9 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS12110 5c387d6067b12d8574c994e0ad0ec72e 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 135 149 2.6E-9 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS12110 5c387d6067b12d8574c994e0ad0ec72e 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 177 2.6E-9 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS12110 5c387d6067b12d8574c994e0ad0ec72e 207 Gene3D G3DSA:1.10.10.10 126 189 1.2E-16 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12110 5c387d6067b12d8574c994e0ad0ec72e 207 SMART SM00421 132 189 4.4E-17 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS12110 5c387d6067b12d8574c994e0ad0ec72e 207 SUPERFAMILY SSF46894 126 187 6.8E-16 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS12110 5c387d6067b12d8574c994e0ad0ec72e 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 134 186 1.5E-15 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS01890 3969d74bdfc4d5f843c270fd981333f7 231 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 199 6.0E-62 T 10-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 RG49_RS01890 3969d74bdfc4d5f843c270fd981333f7 231 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 210 27.355 T 10-03-2017 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 RG49_RS01890 3969d74bdfc4d5f843c270fd981333f7 231 PIRSF PIRSF006102 1 219 2.8E-79 T 10-03-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 RG49_RS01890 3969d74bdfc4d5f843c270fd981333f7 231 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 7 208 4.9E-81 T 10-03-2017 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 RG49_RS20180 6e54240b246735d5a285824d43665226 384 SUPERFAMILY SSF55973 112 232 7.46E-52 T 10-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 10-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 Gene3D G3DSA:3.30.300.10 244 381 4.2E-72 T 10-03-2017 RG49_RS20180 6e54240b246735d5a285824d43665226 384 SUPERFAMILY SSF55973 233 382 9.03E-72 T 10-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 380 1.5E-201 T 10-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 SUPERFAMILY SSF55973 3 109 1.29E-47 T 10-03-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 5.6E-43 T 10-03-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 Gene3D G3DSA:3.30.300.10 136 233 4.4E-44 T 10-03-2017 RG49_RS20180 6e54240b246735d5a285824d43665226 384 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 381 60.288 T 10-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 370 5.7E-70 T 10-03-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 Gene3D G3DSA:3.30.300.10 11 135 1.3E-50 T 10-03-2017 RG49_RS20180 6e54240b246735d5a285824d43665226 384 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 10-03-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 PIRSF PIRSF000497 1 382 2.4E-176 T 10-03-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS20180 6e54240b246735d5a285824d43665226 384 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 1.2E-45 T 10-03-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 RG49_RS15055 0fec6e3bbfb8934915d257302668f4e2 299 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 11 273 3.7E-93 T 10-03-2017 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 RG49_RS15055 0fec6e3bbfb8934915d257302668f4e2 299 SUPERFAMILY SSF103481 199 278 1.19E-9 T 10-03-2017 RG49_RS15055 0fec6e3bbfb8934915d257302668f4e2 299 SUPERFAMILY SSF103481 35 130 4.71E-6 T 10-03-2017 RG49_RS15055 0fec6e3bbfb8934915d257302668f4e2 299 Pfam PF00892 EamA-like transporter family 139 274 7.7E-12 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS15055 0fec6e3bbfb8934915d257302668f4e2 299 Pfam PF00892 EamA-like transporter family 2 128 9.0E-8 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS19645 1717100b8891bada43f38885bdb45c2b 131 Gene3D G3DSA:1.10.260.40 74 125 2.7E-10 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS19645 1717100b8891bada43f38885bdb45c2b 131 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 47 8.6E-12 T 10-03-2017 IPR022453 Zinc finger, MqsA-type RG49_RS19645 1717100b8891bada43f38885bdb45c2b 131 SMART SM00530 73 127 5.7E-7 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS19645 1717100b8891bada43f38885bdb45c2b 131 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1 131 5.5E-56 T 10-03-2017 IPR032758 Antitoxin MqsA/HigA-2 RG49_RS19645 1717100b8891bada43f38885bdb45c2b 131 TIGRFAM TIGR03830 CxxCG_CxxCG_HTH: putative zinc finger/helix-turn-helix protein, YgiT family 3 131 7.6E-44 T 10-03-2017 IPR022452 Antitoxin MqsA RG49_RS19645 1717100b8891bada43f38885bdb45c2b 131 SUPERFAMILY SSF47413 69 126 3.07E-8 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS19465 588547ef3c4d62c7c322e82d0e2fdbbf 206 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 27 204 2.9E-53 T 10-03-2017 IPR016476 SH3 domain protein RG49_RS19465 588547ef3c4d62c7c322e82d0e2fdbbf 206 Pfam PF08239 Bacterial SH3 domain 35 85 3.6E-9 T 10-03-2017 IPR003646 SH3-like domain, bacterial-type RG49_RS19465 588547ef3c4d62c7c322e82d0e2fdbbf 206 PIRSF PIRSF006158 1 205 3.8E-73 T 10-03-2017 IPR016476 SH3 domain protein RG49_RS19465 588547ef3c4d62c7c322e82d0e2fdbbf 206 SMART SM00287 23 89 8.2E-16 T 10-03-2017 IPR003646 SH3-like domain, bacterial-type RG49_RS21710 d30c3989e5aaef4ce73878a434b0de67 319 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 7 319 6.2E-143 T 10-03-2017 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 RG49_RS21710 d30c3989e5aaef4ce73878a434b0de67 319 PIRSF PIRSF000355 2 316 5.0E-78 T 10-03-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21710 d30c3989e5aaef4ce73878a434b0de67 319 Pfam PF00268 Ribonucleotide reductase, small chain 9 280 4.9E-84 T 10-03-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21710 d30c3989e5aaef4ce73878a434b0de67 319 SUPERFAMILY SSF47240 6 319 3.25E-101 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS21710 d30c3989e5aaef4ce73878a434b0de67 319 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 97 113 - T 10-03-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 RG49_RS21710 d30c3989e5aaef4ce73878a434b0de67 319 Gene3D G3DSA:1.10.620.20 7 280 4.5E-89 T 10-03-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 RG49_RS16215 79ee4cfd255906487645a5993f85b1d1 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 1.2E-27 T 10-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS16215 79ee4cfd255906487645a5993f85b1d1 78 SUPERFAMILY SSF143800 2 77 6.28E-30 T 10-03-2017 RG49_RS16215 79ee4cfd255906487645a5993f85b1d1 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.212 T 10-03-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS16215 79ee4cfd255906487645a5993f85b1d1 78 Pfam PF00830 Ribosomal L28 family 3 62 1.6E-25 T 10-03-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS16215 79ee4cfd255906487645a5993f85b1d1 78 Gene3D G3DSA:2.30.170.40 2 77 7.8E-36 T 10-03-2017 RG49_RS08040 381637fb7231394b5c5a29e56a8cf20b 510 Gene3D G3DSA:3.40.1080.10 29 238 4.8E-108 T 10-03-2017 RG49_RS08040 381637fb7231394b5c5a29e56a8cf20b 510 TIGRFAM TIGR01584 citF: citrate lyase, alpha subunit 36 510 2.5E-246 T 10-03-2017 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 RG49_RS08040 381637fb7231394b5c5a29e56a8cf20b 510 SUPERFAMILY SSF100950 35 238 2.16E-76 T 10-03-2017 RG49_RS08040 381637fb7231394b5c5a29e56a8cf20b 510 SUPERFAMILY SSF100950 242 508 8.37E-59 T 10-03-2017 RG49_RS08040 381637fb7231394b5c5a29e56a8cf20b 510 PIRSF PIRSF009451 1 510 6.4E-273 T 10-03-2017 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 RG49_RS08040 381637fb7231394b5c5a29e56a8cf20b 510 Pfam PF04223 Citrate lyase, alpha subunit (CitF) 43 508 3.5E-274 T 10-03-2017 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 RG49_RS08040 381637fb7231394b5c5a29e56a8cf20b 510 Gene3D G3DSA:3.40.810.20 242 483 1.8E-76 T 10-03-2017 RG49_RS06875 98b2e1906ad65f44045755ea010c6c0f 249 SUPERFAMILY SSF69572 3 248 1.7E-87 T 10-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 RG49_RS06875 98b2e1906ad65f44045755ea010c6c0f 249 Gene3D G3DSA:3.40.50.720 3 249 3.1E-79 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06875 98b2e1906ad65f44045755ea010c6c0f 249 TIGRFAM TIGR02355 moeB: molybdopterin synthase sulfurylase MoeB 8 247 4.7E-138 T 10-03-2017 IPR012730 Molybdopterin synthase sulfurylase MoeB GO:0006777 MetaCyc: PWY-6823 RG49_RS06875 98b2e1906ad65f44045755ea010c6c0f 249 Pfam PF00899 ThiF family 12 244 2.7E-64 T 10-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 RG49_RS08125 f6d1510051046d56009b53e5ef373284 386 Gene3D G3DSA:3.40.640.10 45 272 1.1E-71 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS08125 f6d1510051046d56009b53e5ef373284 386 SUPERFAMILY SSF53383 10 386 2.79E-100 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS08125 f6d1510051046d56009b53e5ef373284 386 Pfam PF00155 Aminotransferase class I and II 32 383 2.9E-58 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS08125 f6d1510051046d56009b53e5ef373284 386 Gene3D G3DSA:3.90.1150.10 273 385 4.3E-24 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS06990 62dda8a7ba77b082c5198a3dd48c36d2 335 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 32 325 53.612 T 10-03-2017 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 RG49_RS06990 62dda8a7ba77b082c5198a3dd48c36d2 335 Gene3D G3DSA:3.40.50.150 116 299 6.3E-9 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS06990 62dda8a7ba77b082c5198a3dd48c36d2 335 Pfam PF05971 Protein of unknown function (DUF890) 30 323 3.5E-154 T 10-03-2017 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 RG49_RS06990 62dda8a7ba77b082c5198a3dd48c36d2 335 PIRSF PIRSF029038 22 335 1.9E-149 T 10-03-2017 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 RG49_RS06990 62dda8a7ba77b082c5198a3dd48c36d2 335 SUPERFAMILY SSF53335 70 323 6.55E-28 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS10350 57176eedd3620e564c763a4e9c379118 125 Pfam PF06530 Phage antitermination protein Q 2 124 3.7E-45 T 10-03-2017 IPR010534 Bacteriophage 933W, GpQ GO:0003677|GO:0060567 RG49_RS07215 d21ee2d45d2f1b00d1430aeaf33664ab 229 Gene3D G3DSA:1.10.3720.10 8 226 4.9E-44 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07215 d21ee2d45d2f1b00d1430aeaf33664ab 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 215 6.0E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS07215 d21ee2d45d2f1b00d1430aeaf33664ab 229 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 221 4.0E-71 T 10-03-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 RG49_RS07215 d21ee2d45d2f1b00d1430aeaf33664ab 229 SUPERFAMILY SSF161098 6 220 5.63E-50 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS21555 a2d189749af6d11797f208916dc8dacd 119 PIRSF PIRSF011474 1 119 1.3E-47 T 10-03-2017 IPR009693 Glucitol operon activator RG49_RS21555 a2d189749af6d11797f208916dc8dacd 119 Pfam PF06923 Glucitol operon activator protein (GutM) 5 110 9.7E-36 T 10-03-2017 IPR009693 Glucitol operon activator RG49_RS22340 60641f629888667b5b1346e1f87fde86 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 317 3.9E-43 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS25125 6fab5e35c0b0ff4503f90ad29c7c4716 84 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 1.9E-43 T 10-03-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 RG49_RS25125 6fab5e35c0b0ff4503f90ad29c7c4716 84 SUPERFAMILY SSF143011 2 83 2.35E-28 T 10-03-2017 RG49_RS25125 6fab5e35c0b0ff4503f90ad29c7c4716 84 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 1.0E-39 T 10-03-2017 IPR009614 Toxin YoeB GO:0004519|GO:0006401 RG49_RS25010 11dd4b9bfdbabe43c50e9e6839c17782 292 SUPERFAMILY SSF53448 4 289 1.76E-97 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS25010 11dd4b9bfdbabe43c50e9e6839c17782 292 Pfam PF00483 Nucleotidyl transferase 5 241 6.7E-74 T 10-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 RG49_RS25010 11dd4b9bfdbabe43c50e9e6839c17782 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 5 290 1.2E-164 T 10-03-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 RG49_RS25010 11dd4b9bfdbabe43c50e9e6839c17782 292 Gene3D G3DSA:3.90.550.10 4 268 1.1E-71 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS23000 480a37ce631a4078d4ba92298c3e15e1 338 Pfam PF13531 Bacterial extracellular solute-binding protein 38 286 1.4E-40 T 10-03-2017 RG49_RS23000 480a37ce631a4078d4ba92298c3e15e1 338 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 53 65 - T 10-03-2017 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 RG49_RS23000 480a37ce631a4078d4ba92298c3e15e1 338 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 13 332 2.6E-184 T 10-03-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 RG49_RS23000 480a37ce631a4078d4ba92298c3e15e1 338 SUPERFAMILY SSF53850 24 332 3.87E-81 T 10-03-2017 RG49_RS23000 480a37ce631a4078d4ba92298c3e15e1 338 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 151 159 - T 10-03-2017 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 RG49_RS23000 480a37ce631a4078d4ba92298c3e15e1 338 Gene3D G3DSA:3.40.190.10 26 168 9.2E-44 T 10-03-2017 RG49_RS23000 480a37ce631a4078d4ba92298c3e15e1 338 Gene3D G3DSA:3.40.190.10 180 301 1.4E-27 T 10-03-2017 RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 SUPERFAMILY SSF47413 11 67 4.93E-12 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 Gene3D G3DSA:3.40.50.2300 176 336 9.2E-15 T 10-03-2017 RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 SUPERFAMILY SSF53822 70 336 5.69E-30 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 59 3.1E-15 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 SMART SM00354 9 82 1.7E-25 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 Gene3D G3DSA:1.10.260.40 10 69 6.5E-18 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 Gene3D G3DSA:3.40.50.2300 70 175 2.9E-27 T 10-03-2017 RG49_RS24720 d2bb2f738d3ae319512e5c2bd1035199 343 Pfam PF13407 Periplasmic binding protein domain 73 280 3.6E-12 T 10-03-2017 IPR025997 Periplasmic binding protein RG49_RS07290 a05936d8618c73e9c4f7528e21cb3d45 239 Pfam PF04973 Nicotinamide mononucleotide transporter 23 226 4.9E-51 T 10-03-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 RG49_RS07290 a05936d8618c73e9c4f7528e21cb3d45 239 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 22 231 4.5E-74 T 10-03-2017 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 PIRSF PIRSF002097 1 98 4.0E-46 T 10-03-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 Gene3D G3DSA:1.10.10.60 27 98 1.7E-28 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 78 98 8.3E-13 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 61 78 8.3E-13 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 Hamap MF_00166 DNA-binding protein Fis [fis]. 1 98 33.769 T 10-03-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 57 69 7.6E-35 T 10-03-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 42 57 7.6E-35 T 10-03-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 26 42 7.6E-35 T 10-03-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 9 26 7.6E-35 T 10-03-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 Pfam PF02954 Bacterial regulatory protein, Fis family 55 95 3.7E-14 T 10-03-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 RG49_RS18300 e9ff87b2f6cbc07850e519f60813e1f6 98 SUPERFAMILY SSF46689 4 98 3.88E-27 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS17870 806279ae507c35c6fffa477f138c7919 270 Gene3D G3DSA:1.10.287.460 30 134 8.3E-45 T 10-03-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 RG49_RS17870 806279ae507c35c6fffa477f138c7919 270 Gene3D G3DSA:3.10.50.40 135 249 2.3E-45 T 10-03-2017 RG49_RS17870 806279ae507c35c6fffa477f138c7919 270 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 246 8.7E-29 T 10-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 RG49_RS17870 806279ae507c35c6fffa477f138c7919 270 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 33 152 1.3E-36 T 10-03-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 RG49_RS17870 806279ae507c35c6fffa477f138c7919 270 SUPERFAMILY SSF54534 41 249 2.36E-65 T 10-03-2017 RG49_RS17280 229228abf7f50ce11a749be4414c6577 45 Pfam PF15945 Domain of unknown function (DUF4753) 1 45 4.4E-20 T 10-03-2017 IPR031859 Protein of unknown function DUF4753 RG49_RS11505 108aa625085bb3e3d8f6207045d4692e 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 200 44.815 T 10-03-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 RG49_RS11505 108aa625085bb3e3d8f6207045d4692e 201 SUPERFAMILY SSF52016 4 195 3.34E-60 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS11505 108aa625085bb3e3d8f6207045d4692e 201 Gene3D G3DSA:3.20.19.10 6 196 1.3E-48 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS11505 108aa625085bb3e3d8f6207045d4692e 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 3 189 5.9E-104 T 10-03-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 RG49_RS11505 108aa625085bb3e3d8f6207045d4692e 201 Pfam PF00694 Aconitase C-terminal domain 3 126 5.1E-40 T 10-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS10085 92fedb702935db05e08b71ea6cdec06f 287 SUPERFAMILY SSF52540 24 241 3.22E-26 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10085 92fedb702935db05e08b71ea6cdec06f 287 Pfam PF01926 50S ribosome-binding GTPase 39 132 1.0E-14 T 10-03-2017 IPR006073 GTP binding domain GO:0005525 RG49_RS10085 92fedb702935db05e08b71ea6cdec06f 287 Gene3D G3DSA:3.40.50.300 19 48 4.1E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10085 92fedb702935db05e08b71ea6cdec06f 287 Gene3D G3DSA:3.40.50.300 49 216 1.2E-24 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 5.2E-60 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 5.2E-60 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 5.2E-60 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 5.2E-60 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 5.2E-60 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 5.2E-60 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 Gene3D G3DSA:2.40.50.140 1 123 5.3E-65 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 2.6E-70 T 10-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 Pfam PF00164 Ribosomal protein S12/S23 6 123 1.8E-43 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.634 T 10-03-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 SUPERFAMILY SSF50249 3 123 1.63E-51 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 PIRSF PIRSF002133 1 124 7.8E-54 T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17895 29495e0d2573e3eb61572cc610d4e48b 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 10-03-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS17600 f7085bdf5fd53b4058ad6dee28a70a29 186 SUPERFAMILY SSF55811 3 182 2.84E-38 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS17600 f7085bdf5fd53b4058ad6dee28a70a29 186 Gene3D G3DSA:3.90.79.10 9 183 1.0E-42 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS17600 f7085bdf5fd53b4058ad6dee28a70a29 186 Pfam PF00293 NUDIX domain 46 150 3.5E-13 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS17600 f7085bdf5fd53b4058ad6dee28a70a29 186 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS00225 04f7883eb4067e4777f3da3174173415 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 68 84 2.6E-22 T 10-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 RG49_RS00225 04f7883eb4067e4777f3da3174173415 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 89 102 2.6E-22 T 10-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 RG49_RS00225 04f7883eb4067e4777f3da3174173415 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 33 49 2.6E-22 T 10-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 RG49_RS00225 04f7883eb4067e4777f3da3174173415 104 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 2 104 18.056 T 10-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 RG49_RS00225 04f7883eb4067e4777f3da3174173415 104 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 2 104 7.2E-43 T 10-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 RG49_RS00225 04f7883eb4067e4777f3da3174173415 104 Pfam PF02049 Flagellar hook-basal body complex protein FliE 18 104 7.4E-28 T 10-03-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 RG49_RS10880 4b1e42e2cf1af9aa6558949461a02c9d 129 SUPERFAMILY SSF54593 3 128 1.75E-32 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS10880 4b1e42e2cf1af9aa6558949461a02c9d 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 126 9.2E-23 T 10-03-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain RG49_RS10880 4b1e42e2cf1af9aa6558949461a02c9d 129 Gene3D G3DSA:3.10.180.10 3 128 1.5E-36 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS23795 22f73f32dce657aba511b0ead2d927a8 88 Pfam PF11183 Polymyxin resistance protein PmrD 1 82 1.5E-40 T 10-03-2017 RG49_RS23795 22f73f32dce657aba511b0ead2d927a8 88 ProDom PD028730 PMRD RESISTANCE POLYMYXIN B ANTIBIOTIC 1 82 6.0E-42 T 10-03-2017 IPR020146 Signal transduction protein PmrD RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 Pfam PF01750 Hydrogenase maturation protease 23 140 2.5E-30 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 PRINTS PR00446 Hydrogen uptake protein signature 3 15 3.0E-13 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 PRINTS PR00446 Hydrogen uptake protein signature 15 26 3.0E-13 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 PRINTS PR00446 Hydrogen uptake protein signature 33 50 3.0E-13 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 PRINTS PR00446 Hydrogen uptake protein signature 56 66 3.0E-13 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 PRINTS PR00446 Hydrogen uptake protein signature 67 83 3.0E-13 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 140 2.9E-35 T 10-03-2017 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 Gene3D G3DSA:3.40.50.1450 5 142 1.7E-24 T 10-03-2017 IPR023430 Peptidase HybD-like domain RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 TIGRFAM TIGR00142 hycI: hydrogenase maturation peptidase HycI 3 147 2.4E-69 T 10-03-2017 IPR004420 Peptidase A31, hydrogenase maturation protease HycI GO:0008233 RG49_RS21495 3fcee689e8d0c096e82c6ece969c382c 156 SUPERFAMILY SSF53163 4 152 2.17E-35 T 10-03-2017 IPR023430 Peptidase HybD-like domain RG49_RS01660 cec23b87dbcb2822c751fda67bdbd9a6 69 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 69 5.0E-34 T 10-03-2017 RG49_RS01660 cec23b87dbcb2822c751fda67bdbd9a6 69 Pfam PF10965 Protein of unknown function (DUF2767) 1 67 1.7E-34 T 10-03-2017 IPR024493 Protein of unknown function DUF2767 RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 Gene3D G3DSA:3.40.640.10 17 258 4.5E-103 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 361 51.635 T 10-03-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 SUPERFAMILY SSF53383 4 362 7.23E-117 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 Gene3D G3DSA:3.90.1150.10 260 361 5.4E-43 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 208 - T 10-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 PIRSF PIRSF000525 1 362 1.8E-149 T 10-03-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 361 2.3E-154 T 10-03-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 RG49_RS06200 b7a12bfd41d1b3d3a194d047eb9198dc 362 Pfam PF00266 Aminotransferase class-V 4 350 9.6E-76 T 10-03-2017 IPR000192 Aminotransferase class V domain RG49_RS04685 9f83c2e522d2022cb248e1ccc40978fb 244 Gene3D G3DSA:2.30.110.10 11 102 6.6E-6 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS04685 9f83c2e522d2022cb248e1ccc40978fb 244 Pfam PF07238 PilZ domain 112 230 3.2E-12 T 10-03-2017 IPR009875 PilZ domain GO:0035438 RG49_RS04685 9f83c2e522d2022cb248e1ccc40978fb 244 Gene3D G3DSA:2.40.10.220 113 242 3.0E-42 T 10-03-2017 RG49_RS04685 9f83c2e522d2022cb248e1ccc40978fb 244 Hamap MF_01457 Flagellar brake protein YcgR [ycgR]. 3 239 29.615 T 10-03-2017 IPR023787 Type III secretion system flagellar brake protein YcgR GO:0035438|GO:0071945 RG49_RS04685 9f83c2e522d2022cb248e1ccc40978fb 244 Pfam PF07317 Flagellar regulator YcgR 8 109 5.0E-25 T 10-03-2017 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal RG49_RS04090 7b1f50fbc9eeb38883ab3222adb10ef5 296 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 66 2.6E-9 T 10-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain RG49_RS04090 7b1f50fbc9eeb38883ab3222adb10ef5 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 292 1.1E-18 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04090 7b1f50fbc9eeb38883ab3222adb10ef5 296 Gene3D G3DSA:1.10.3720.10 86 290 2.4E-17 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04090 7b1f50fbc9eeb38883ab3222adb10ef5 296 SUPERFAMILY SSF161098 90 277 7.19E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS25170 ae5df7f364eb27de01a616557821937c 352 Pfam PF04632 Fusaric acid resistance protein family 21 316 3.9E-18 T 10-03-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 RG49_RS10730 0e3a268714fb321316c2df60fa60fd6c 243 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 7 242 7.5E-96 T 10-03-2017 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS10730 0e3a268714fb321316c2df60fa60fd6c 243 SMART SM00479 7 184 1.9E-51 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS10730 0e3a268714fb321316c2df60fa60fd6c 243 SUPERFAMILY SSF53098 7 184 1.48E-52 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10730 0e3a268714fb321316c2df60fa60fd6c 243 Gene3D G3DSA:3.30.420.10 7 184 9.1E-65 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS10730 0e3a268714fb321316c2df60fa60fd6c 243 Pfam PF00929 Exonuclease 9 175 3.8E-42 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS10730 0e3a268714fb321316c2df60fa60fd6c 243 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 6 225 5.8E-100 T 10-03-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 RG49_RS02270 22e673bc7bebaa5adeff59495ea2b90a 45 Gene3D G3DSA:1.10.10.60 11 43 1.8E-4 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS02270 22e673bc7bebaa5adeff59495ea2b90a 45 Pfam PF12759 InsA C-terminal domain 1 45 1.6E-31 T 10-03-2017 IPR024431 Insertion element IS1 protein InsA, helix-turn-helix domain RG49_RS04925 0c1ff945501c09b9a16a2183e25d3a4e 416 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 1 416 2.4E-242 T 10-03-2017 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 RG49_RS04925 0c1ff945501c09b9a16a2183e25d3a4e 416 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 29 412 1.7E-117 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS04925 0c1ff945501c09b9a16a2183e25d3a4e 416 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 303 322 - T 10-03-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 RG49_RS04925 0c1ff945501c09b9a16a2183e25d3a4e 416 SUPERFAMILY SSF53659 3 416 1.29E-150 T 10-03-2017 RG49_RS04925 0c1ff945501c09b9a16a2183e25d3a4e 416 Gene3D G3DSA:3.40.718.10 10 416 8.5E-171 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS04925 0c1ff945501c09b9a16a2183e25d3a4e 416 SMART SM01329 28 412 4.7E-182 T 10-03-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-22 T 10-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 PRINTS PR01249 Ribosomal protein L31 signature 31 46 1.0E-22 T 10-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 PRINTS PR01249 Ribosomal protein L31 signature 46 64 1.0E-22 T 10-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 10-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 Pfam PF01197 Ribosomal protein L31 1 65 6.2E-31 T 10-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 32.097 T 10-03-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 SUPERFAMILY SSF143800 1 66 1.02E-27 T 10-03-2017 RG49_RS14445 091bb03c9d1e8734ac0da1ad6ed169e2 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 6.9E-35 T 10-03-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS09605 68a7b6ffd74481e53076568ba8c61d1f 677 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 55 503 3.7E-182 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS09605 68a7b6ffd74481e53076568ba8c61d1f 677 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 17 501 1.9E-174 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS09605 68a7b6ffd74481e53076568ba8c61d1f 677 ProSitePatterns PS01303 BCCT family of transporters signature. 318 327 - T 10-03-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS04900 334cb1989176b9a17bc772a72cd64e84 403 Pfam PF00563 EAL domain 173 388 2.8E-48 T 10-03-2017 IPR001633 EAL domain RG49_RS04900 334cb1989176b9a17bc772a72cd64e84 403 SMART SM01034 2 94 1.1E-37 T 10-03-2017 IPR007024 BLUF domain GO:0009882|GO:0071949 RG49_RS04900 334cb1989176b9a17bc772a72cd64e84 403 SUPERFAMILY SSF141868 173 389 3.01E-43 T 10-03-2017 IPR001633 EAL domain RG49_RS04900 334cb1989176b9a17bc772a72cd64e84 403 Pfam PF04940 Sensors of blue-light using FAD 2 92 1.4E-24 T 10-03-2017 IPR007024 BLUF domain GO:0009882|GO:0071949 RG49_RS04900 334cb1989176b9a17bc772a72cd64e84 403 SUPERFAMILY SSF54975 1 132 5.89E-36 T 10-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS04900 334cb1989176b9a17bc772a72cd64e84 403 SMART SM00052 145 394 5.9E-62 T 10-03-2017 IPR001633 EAL domain RG49_RS04900 334cb1989176b9a17bc772a72cd64e84 403 Gene3D G3DSA:3.20.20.450 175 389 5.1E-40 T 10-03-2017 IPR001633 EAL domain RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 Pfam PF04397 LytTr DNA-binding domain 144 237 1.6E-24 T 10-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-25 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 Gene3D G3DSA:2.20.25.10 214 239 3.2E-7 T 10-03-2017 RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 SMART SM00448 2 112 1.4E-29 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 SUPERFAMILY SSF52172 1 123 8.97E-32 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 Gene3D G3DSA:3.40.50.2300 1 122 5.4E-32 T 10-03-2017 RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 SMART SM00850 143 238 4.5E-27 T 10-03-2017 IPR007492 LytTR DNA-binding domain GO:0003677 RG49_RS24560 19ff1b5d6bf0dc49e6340de80d654268 239 Gene3D G3DSA:2.40.50.40 135 201 1.2E-10 T 10-03-2017 RG49_RS21505 6394ff7098b0249d29a4a3c8674f4de7 485 Pfam PF02378 Phosphotransferase system, EIIC 113 396 3.5E-42 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS21505 6394ff7098b0249d29a4a3c8674f4de7 485 SUPERFAMILY SSF55604 8 82 1.7E-21 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS21505 6394ff7098b0249d29a4a3c8674f4de7 485 Pfam PF00367 phosphotransferase system, EIIB 11 43 5.2E-15 T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS21505 6394ff7098b0249d29a4a3c8674f4de7 485 Gene3D G3DSA:3.30.1360.60 4 82 1.6E-27 T 10-03-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 RG49_RS21505 6394ff7098b0249d29a4a3c8674f4de7 485 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 154 441 1.3E-88 T 10-03-2017 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 RG49_RS21505 6394ff7098b0249d29a4a3c8674f4de7 485 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 10-03-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 RG49_RS15790 6bb27f9960fa9182d82beeeeb4bc8a5c 137 Gene3D G3DSA:2.60.40.790 4 137 3.9E-18 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS15790 6bb27f9960fa9182d82beeeeb4bc8a5c 137 Hamap MF_02000 Small heat shock protein IbpA [ibpA]. 1 137 51.246 T 10-03-2017 IPR023728 Small heat shock protein IbpA RG49_RS15790 6bb27f9960fa9182d82beeeeb4bc8a5c 137 SUPERFAMILY SSF49764 30 137 4.88E-20 T 10-03-2017 IPR008978 HSP20-like chaperone RG49_RS15790 6bb27f9960fa9182d82beeeeb4bc8a5c 137 Pfam PF00011 Hsp20/alpha crystallin family 42 137 5.4E-23 T 10-03-2017 IPR002068 Alpha crystallin/Hsp20 domain RG49_RS17200 8331c8df7ca3a6355b182e261c86154c 349 Pfam PF01594 Domain of unknown function DUF20 14 328 4.6E-82 T 10-03-2017 IPR002549 Transmembrane protein TqsA-like RG49_RS06915 8078487707ef5c65c7b25c94e19b1c5f 372 Pfam PF03600 Citrate transporter 25 304 3.4E-25 T 10-03-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 ProSitePatterns PS00928 Trehalase signature 2. 446 455 - T 10-03-2017 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 Hamap MF_01060 Periplasmic trehalase [treA]. 3 534 83.876 T 10-03-2017 IPR023720 Trehalase, periplasmic GO:0004555|GO:0005993|GO:0042597|GO:0071474 KEGG: 00500+3.2.1.28 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 Pfam PF01204 Trehalase 55 532 3.6E-177 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 SUPERFAMILY SSF48208 39 539 5.83E-175 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 PRINTS PR00744 Glycosyl hydrolase family 37 signature 191 209 4.6E-50 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 PRINTS PR00744 Glycosyl hydrolase family 37 signature 266 283 4.6E-50 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 PRINTS PR00744 Glycosyl hydrolase family 37 signature 439 455 4.6E-50 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 PRINTS PR00744 Glycosyl hydrolase family 37 signature 375 391 4.6E-50 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 PRINTS PR00744 Glycosyl hydrolase family 37 signature 516 529 4.6E-50 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 PRINTS PR00744 Glycosyl hydrolase family 37 signature 332 349 4.6E-50 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 PRINTS PR00744 Glycosyl hydrolase family 37 signature 300 317 4.6E-50 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS04670 d4bc5910f71bdea9b94628450da93565 565 ProSitePatterns PS00927 Trehalase signature 1. 149 162 - T 10-03-2017 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS18720 902bb28bbb38b20e4282f307603bca62 321 SUPERFAMILY SSF103481 41 143 2.35E-12 T 10-03-2017 RG49_RS18720 902bb28bbb38b20e4282f307603bca62 321 Pfam PF00892 EamA-like transporter family 7 142 1.1E-28 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS18720 902bb28bbb38b20e4282f307603bca62 321 Pfam PF00892 EamA-like transporter family 159 291 4.9E-17 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS12720 d29caf3d891e07fc006be50965ca02db 450 SUPERFAMILY SSF111283 17 449 1.44E-133 T 10-03-2017 RG49_RS12720 d29caf3d891e07fc006be50965ca02db 450 Pfam PF01523 Putative modulator of DNA gyrase 36 326 7.9E-55 T 10-03-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 SUPERFAMILY SSF51556 8 347 2.59E-149 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 ProSitePatterns PS00482 Dihydroorotase signature 1. 15 23 - T 10-03-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 ProSitePatterns PS00483 Dihydroorotase signature 2. 249 260 - T 10-03-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 Gene3D G3DSA:3.20.20.140 6 347 5.4E-135 T 10-03-2017 RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 PIRSF PIRSF001237 4 348 6.2E-142 T 10-03-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 Hamap MF_00219 Dihydroorotase [pyrC]. 6 347 63.633 T 10-03-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 8 347 8.2E-169 T 10-03-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 RG49_RS05335 7747d65c098a664bc683352e8734b7c0 348 Pfam PF01979 Amidohydrolase family 15 307 6.5E-22 T 10-03-2017 IPR006680 Amidohydrolase-related GO:0016787 RG49_RS23980 18a3be85091f4844cea48c02101cf185 549 Pfam PF08486 Stage II sporulation protein 312 375 3.1E-5 T 10-03-2017 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal RG49_RS23980 18a3be85091f4844cea48c02101cf185 549 SUPERFAMILY SSF56601 52 225 1.07E-7 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS23980 18a3be85091f4844cea48c02101cf185 549 Pfam PF10062 Predicted secreted protein (DUF2300) 84 205 1.7E-38 T 10-03-2017 IPR018748 Domain of unknown function DUF2300, secreted RG49_RS23980 18a3be85091f4844cea48c02101cf185 549 Pfam PF10062 Predicted secreted protein (DUF2300) 412 531 2.2E-41 T 10-03-2017 IPR018748 Domain of unknown function DUF2300, secreted RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 SMART SM00079 42 262 7.5E-5 T 10-03-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 1.3E-71 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 65 78 - T 10-03-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 Gene3D G3DSA:3.40.190.10 120 222 4.1E-33 T 10-03-2017 RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 Gene3D G3DSA:3.40.190.10 223 265 9.2E-47 T 10-03-2017 RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 Gene3D G3DSA:3.40.190.10 38 119 9.2E-47 T 10-03-2017 RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 SUPERFAMILY SSF53850 15 264 2.09E-76 T 10-03-2017 RG49_RS00300 a8d812f6bc44770bd2caf9a4f00b55f7 266 SMART SM00062 42 263 5.8E-88 T 10-03-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF RG49_RS17575 beb23963219af59bac4b87ad9427731d 574 Pfam PF13687 Domain of unknown function (DUF4153) 150 389 1.2E-44 T 10-03-2017 IPR025291 Protein of unknown function DUF4153 RG49_RS16755 29c6399dfa9cae69ed84165c8b924865 402 Gene3D G3DSA:1.20.1250.20 209 392 2.5E-21 T 10-03-2017 RG49_RS16755 29c6399dfa9cae69ed84165c8b924865 402 Pfam PF07690 Major Facilitator Superfamily 26 231 1.7E-18 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS16755 29c6399dfa9cae69ed84165c8b924865 402 Gene3D G3DSA:1.20.1250.20 8 194 3.4E-18 T 10-03-2017 RG49_RS16755 29c6399dfa9cae69ed84165c8b924865 402 SUPERFAMILY SSF103473 8 393 9.94E-50 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS16755 29c6399dfa9cae69ed84165c8b924865 402 TIGRFAM TIGR00890 2A0111: oxalate/formate antiporter family transporter 9 383 3.7E-144 T 10-03-2017 IPR004741 Oxalate/formate antiporter family transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS21775 356b6e7518ccc81b5b40937fefb56545 466 PIRSF PIRSF006060 1 462 1.1E-73 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS21775 356b6e7518ccc81b5b40937fefb56545 466 TIGRFAM TIGR01773 GABAperm: GABA permease 1 452 1.9E-258 T 10-03-2017 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 RG49_RS21775 356b6e7518ccc81b5b40937fefb56545 466 Pfam PF00324 Amino acid permease 18 456 2.6E-126 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS21775 356b6e7518ccc81b5b40937fefb56545 466 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS17005 789c1488e68dfefde0f2caf41c3e34bd 176 Gene3D G3DSA:1.10.10.10 115 168 3.5E-10 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17005 789c1488e68dfefde0f2caf41c3e34bd 176 Pfam PF00196 Bacterial regulatory proteins, luxR family 115 168 8.0E-9 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17005 789c1488e68dfefde0f2caf41c3e34bd 176 SMART SM00421 113 170 2.1E-12 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS17005 789c1488e68dfefde0f2caf41c3e34bd 176 SUPERFAMILY SSF46894 97 169 3.27E-10 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS05710 0ede193f41465043992af90d9da0a1fc 199 Hamap MF_01150 Chaperone protein TorD [torD]. 1 199 31.111 T 10-03-2017 IPR023069 Chaperone TorD RG49_RS05710 0ede193f41465043992af90d9da0a1fc 199 Gene3D G3DSA:1.10.3480.10 4 195 3.8E-34 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS05710 0ede193f41465043992af90d9da0a1fc 199 SUPERFAMILY SSF89155 7 196 2.49E-42 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS05710 0ede193f41465043992af90d9da0a1fc 199 Pfam PF02613 Nitrate reductase delta subunit 48 169 1.1E-24 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 Gene3D G3DSA:3.20.20.80 3 473 2.7E-151 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 4.2E-15 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 4.2E-15 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 4.2E-15 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 4.2E-15 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 4.2E-15 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 SUPERFAMILY SSF51445 2 471 8.94E-161 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 Pfam PF00232 Glycosyl hydrolase family 1 3 470 2.3E-133 T 10-03-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 10-03-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site RG49_RS21500 914bd95cb20352d4df283c90fccbce79 474 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 10-03-2017 IPR018120 Glycoside hydrolase family 1, active site RG49_RS05805 e701190903cc5eb0eef7b8a96ce4f2ce 432 Gene3D G3DSA:3.40.50.1240 140 280 1.2E-52 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05805 e701190903cc5eb0eef7b8a96ce4f2ce 432 Pfam PF00328 Histidine phosphatase superfamily (branch 2) 29 374 1.5E-33 T 10-03-2017 IPR000560 Histidine phosphatase superfamily, clade-2 GO:0003993 RG49_RS05805 e701190903cc5eb0eef7b8a96ce4f2ce 432 ProSitePatterns PS00778 Histidine acid phosphatases active site signature. 319 335 - T 10-03-2017 IPR033379 Histidine acid phosphatase active site RG49_RS05805 e701190903cc5eb0eef7b8a96ce4f2ce 432 Gene3D G3DSA:3.40.50.1240 27 139 1.1E-77 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05805 e701190903cc5eb0eef7b8a96ce4f2ce 432 Gene3D G3DSA:3.40.50.1240 282 431 1.1E-77 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05805 e701190903cc5eb0eef7b8a96ce4f2ce 432 SUPERFAMILY SSF53254 26 429 1.24E-80 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS05805 e701190903cc5eb0eef7b8a96ce4f2ce 432 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 30 44 - T 10-03-2017 IPR033379 Histidine acid phosphatase active site RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 SUPERFAMILY SSF51604 138 415 9.8E-84 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 Gene3D G3DSA:3.30.390.10 8 123 1.3E-17 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 136 1.5E-8 T 10-03-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 SUPERFAMILY SSF54826 7 136 4.18E-32 T 10-03-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 SMART SM00922 184 284 1.1E-14 T 10-03-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 Pfam PF13378 Enolase C-terminal domain-like 187 404 1.1E-39 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 111 136 - T 10-03-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 RG49_RS21110 d2208bd14107377f2ba67dfbe899075c 446 Gene3D G3DSA:3.20.20.120 124 397 4.4E-104 T 10-03-2017 IPR029065 Enolase C-terminal domain-like RG49_RS00150 2a90bea6ed9b321f0e48112c835df2d9 80 Pfam PF10781 Dextransucrase DSRB 19 78 1.1E-35 T 10-03-2017 IPR019717 Dextransucrase DSRB RG49_RS00150 2a90bea6ed9b321f0e48112c835df2d9 80 Hamap MF_01549 Protein DsrB [dsrB]. 19 80 29.631 T 10-03-2017 IPR019717 Dextransucrase DSRB RG49_RS07805 bf23401583b410850baf2635b1fd0b12 359 Gene3D G3DSA:3.40.50.300 131 334 1.3E-89 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07805 bf23401583b410850baf2635b1fd0b12 359 SUPERFAMILY SSF52540 130 331 2.67E-41 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07805 bf23401583b410850baf2635b1fd0b12 359 Pfam PF02562 PhoH-like protein 131 334 9.1E-96 T 10-03-2017 IPR003714 PhoH-like protein GO:0005524 RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 8.0E-5 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 8.0E-5 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 SMART SM00895 85 209 2.4E-17 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 Gene3D G3DSA:1.20.120.530 79 221 2.1E-25 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 Gene3D G3DSA:1.10.10.10 4 76 5.8E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 Pfam PF07729 FCD domain 89 208 8.5E-26 T 10-03-2017 IPR011711 GntR, C-terminal RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 SUPERFAMILY SSF48008 87 216 4.18E-26 T 10-03-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 2.9E-17 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 SUPERFAMILY SSF46785 7 104 7.69E-19 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02510 d8e4d217b3abef1f1d4da4fef71a7ef7 228 SMART SM00345 17 75 2.6E-22 T 10-03-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 RG49_RS03270 19a04d901e8c6a5d37c9e97a9c47115b 326 SUPERFAMILY SSF51161 4 318 5.69E-59 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS03270 19a04d901e8c6a5d37c9e97a9c47115b 326 Gene3D G3DSA:2.160.10.10 242 301 2.8E-26 T 10-03-2017 RG49_RS03270 19a04d901e8c6a5d37c9e97a9c47115b 326 Gene3D G3DSA:2.160.10.10 46 132 2.8E-26 T 10-03-2017 RG49_RS21675 756835e221c97db024e5cd36be0857c6 111 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 104 4.5E-14 T 10-03-2017 IPR008407 Branched-chain amino acid transport, AzlD RG49_RS24350 913f849a181031b124f381472e2e2bff 416 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 201 412 3.5E-66 T 10-03-2017 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 RG49_RS24350 913f849a181031b124f381472e2e2bff 416 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.6E-21 T 10-03-2017 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 RG49_RS24350 913f849a181031b124f381472e2e2bff 416 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 412 2.0E-150 T 10-03-2017 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 RG49_RS09200 00528948409d56eb33f8de5e85ba03b9 154 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 33.307 T 10-03-2017 IPR003791 Protein of unknown function UPF0178 RG49_RS09200 00528948409d56eb33f8de5e85ba03b9 154 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 143 7.0E-49 T 10-03-2017 IPR003791 Protein of unknown function UPF0178 RG49_RS06995 4e25ab31fd829d2217e93cea6d4d306d 86 SUPERFAMILY SSF159871 3 86 5.62E-23 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS06995 4e25ab31fd829d2217e93cea6d4d306d 86 Pfam PF07338 Protein of unknown function (DUF1471) 34 86 1.2E-17 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS06995 4e25ab31fd829d2217e93cea6d4d306d 86 Gene3D G3DSA:3.30.1660.10 19 86 3.0E-28 T 10-03-2017 IPR025543 Dodecin-like RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 25 145 4.7E-41 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 98 115 - T 10-03-2017 IPR018046 Pili assembly chaperone, conserved site RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 Gene3D G3DSA:2.60.40.1070 147 227 2.7E-22 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 167 222 6.6E-13 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 PRINTS PR00969 Pili chaperone signature 26 35 1.4E-31 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 PRINTS PR00969 Pili chaperone signature 126 141 1.4E-31 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 PRINTS PR00969 Pili chaperone signature 99 116 1.4E-31 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 PRINTS PR00969 Pili chaperone signature 161 176 1.4E-31 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 PRINTS PR00969 Pili chaperone signature 71 92 1.4E-31 T 10-03-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 Gene3D G3DSA:2.60.40.360 25 145 5.9E-44 T 10-03-2017 IPR008962 PapD-like RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 SUPERFAMILY SSF49354 22 144 8.11E-40 T 10-03-2017 IPR008962 PapD-like RG49_RS18940 42f411ca14278794ea5de37c9f2580c2 231 SUPERFAMILY SSF49584 145 225 6.54E-19 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS11935 6ed2eb8b203b53e0368a69cf58cb1dd9 173 Pfam PF01931 Protein of unknown function DUF84 7 166 1.1E-52 T 10-03-2017 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 RG49_RS11935 6ed2eb8b203b53e0368a69cf58cb1dd9 173 SUPERFAMILY SSF52972 1 167 3.44E-58 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS11935 6ed2eb8b203b53e0368a69cf58cb1dd9 173 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 171 30.21 T 10-03-2017 IPR002786 Non-canonical purine NTP phosphatase RG49_RS11935 6ed2eb8b203b53e0368a69cf58cb1dd9 173 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 6 170 4.2E-73 T 10-03-2017 IPR002786 Non-canonical purine NTP phosphatase RG49_RS11935 6ed2eb8b203b53e0368a69cf58cb1dd9 173 Gene3D G3DSA:3.90.950.10 2 168 2.0E-63 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS00785 044bd56624cc00b1a4146b2d63aa56af 427 Pfam PF04403 Paraquat-inducible protein A 66 217 1.7E-39 T 10-03-2017 IPR007498 Paraquat-inducible protein A RG49_RS00785 044bd56624cc00b1a4146b2d63aa56af 427 Pfam PF04403 Paraquat-inducible protein A 263 418 2.8E-43 T 10-03-2017 IPR007498 Paraquat-inducible protein A RG49_RS00785 044bd56624cc00b1a4146b2d63aa56af 427 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 16 417 1.4E-211 T 10-03-2017 IPR005219 Conserved hypothetical protein CHP00155 RG49_RS05640 c21718f4952f1e2734919a6f5f970123 230 Hamap MF_00830 Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB [rutB]. 1 228 61.052 T 10-03-2017 IPR019916 Isochorismatase, RutB GO:0016811 KEGG: 00240+3.5.1.110|KEGG: 00311+3.5.1.11 RG49_RS05640 c21718f4952f1e2734919a6f5f970123 230 TIGRFAM TIGR03614 RutB: pyrimidine utilization protein B 3 226 1.9E-138 T 10-03-2017 IPR019916 Isochorismatase, RutB GO:0016811 KEGG: 00240+3.5.1.110|KEGG: 00311+3.5.1.11 RG49_RS05640 c21718f4952f1e2734919a6f5f970123 230 Gene3D G3DSA:3.40.50.850 3 224 2.4E-66 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS05640 c21718f4952f1e2734919a6f5f970123 230 SUPERFAMILY SSF52499 5 221 4.06E-57 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS05640 c21718f4952f1e2734919a6f5f970123 230 Pfam PF00857 Isochorismatase family 18 215 5.2E-41 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS16060 ffb71ad93232fe3b80632d92a082df46 285 SUPERFAMILY SSF53098 107 269 1.24E-37 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS16060 ffb71ad93232fe3b80632d92a082df46 285 Pfam PF13276 HTH-like domain 37 90 5.6E-8 T 10-03-2017 IPR025948 HTH-like domain RG49_RS16060 ffb71ad93232fe3b80632d92a082df46 285 Pfam PF00665 Integrase core domain 114 229 3.7E-28 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS16060 ffb71ad93232fe3b80632d92a082df46 285 Gene3D G3DSA:3.30.420.10 108 267 5.4E-34 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS01555 7450543d04216ab41b2663358d9ffb21 531 PIRSF PIRSF000858 10 530 1.2E-207 T 10-03-2017 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 RG49_RS01555 7450543d04216ab41b2663358d9ffb21 531 SMART SM00882 15 253 5.9E-50 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS01555 7450543d04216ab41b2663358d9ffb21 531 Gene3D G3DSA:3.40.810.20 287 510 5.0E-54 T 10-03-2017 RG49_RS01555 7450543d04216ab41b2663358d9ffb21 531 Pfam PF01144 Coenzyme A transferase 16 252 1.4E-57 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS01555 7450543d04216ab41b2663358d9ffb21 531 SUPERFAMILY SSF100950 15 264 6.85E-81 T 10-03-2017 RG49_RS01555 7450543d04216ab41b2663358d9ffb21 531 Gene3D G3DSA:3.40.1080.10 15 252 9.0E-65 T 10-03-2017 RG49_RS01555 7450543d04216ab41b2663358d9ffb21 531 SUPERFAMILY SSF100950 284 523 3.43E-67 T 10-03-2017 RG49_RS10290 3fb306b0f3118adfe413f285341fcb68 401 Pfam PF05065 Phage capsid family 115 398 4.1E-79 T 10-03-2017 IPR024455 Phage capsid RG49_RS10290 3fb306b0f3118adfe413f285341fcb68 401 SUPERFAMILY SSF56563 107 399 1.19E-72 T 10-03-2017 RG49_RS10290 3fb306b0f3118adfe413f285341fcb68 401 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 6 398 5.3E-116 T 10-03-2017 IPR006444 Phage major capsid protein, HK97 RG49_RS01495 2aa1c4c849cfdcc5e424b888b95747ca 63 Pfam PF10636 Hemin uptake protein hemP 27 63 5.3E-15 T 10-03-2017 IPR019600 Hemin uptake protein HemP RG49_RS01495 2aa1c4c849cfdcc5e424b888b95747ca 63 Gene3D G3DSA:2.10.70.10 23 63 1.6E-18 T 10-03-2017 RG49_RS21345 cc5959dd650c7d726086e66fefc68c5e 349 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 77 90 - T 10-03-2017 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 RG49_RS21345 cc5959dd650c7d726086e66fefc68c5e 349 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 8 167 3.4E-40 T 10-03-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS21345 cc5959dd650c7d726086e66fefc68c5e 349 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 188 337 1.4E-18 T 10-03-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS21345 cc5959dd650c7d726086e66fefc68c5e 349 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 1 342 4.1E-107 T 10-03-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS21345 cc5959dd650c7d726086e66fefc68c5e 349 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 5 342 28.822 T 10-03-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS21345 cc5959dd650c7d726086e66fefc68c5e 349 SUPERFAMILY SSF55120 2 340 2.73E-101 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Gene3D G3DSA:1.25.40.10 19 114 1.0E-20 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 105 132 0.11 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 134 169 3.3E-9 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 244 277 8.3E-9 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 28 63 2.5E-7 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 170 205 1.4E-7 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 65 99 0.0011 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 282 307 0.0091 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Pfam PF08238 Sel1 repeat 207 241 1.4E-6 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 Gene3D G3DSA:1.25.40.10 117 322 5.0E-63 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 27 63 9.4E-7 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 64 99 1.5E-7 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 134 169 7.2E-13 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 100 133 0.0026 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 206 241 1.8E-8 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 170 205 1.2E-10 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 242 277 4.8E-11 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SMART SM00671 278 313 5.4E-6 T 10-03-2017 IPR006597 Sel1-like repeat RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SUPERFAMILY SSF81901 20 113 1.96E-18 T 10-03-2017 RG49_RS07885 e7141893f5c6979bdbe52aaba4abd1d0 327 SUPERFAMILY SSF81901 112 312 5.14E-54 T 10-03-2017 RG49_RS18865 1602ebadc32278b753c30eae8d523080 331 Pfam PF01136 Peptidase family U32 76 330 8.2E-67 T 10-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 RG49_RS18865 1602ebadc32278b753c30eae8d523080 331 SUPERFAMILY SSF51391 11 162 5.23E-6 T 10-03-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 RG49_RS18865 1602ebadc32278b753c30eae8d523080 331 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 10-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 RG49_RS00840 9030c1c05bccbd63c9ee00333b30276d 47 Pfam PF10736 Protein of unknown function (DUF2627) 1 38 1.3E-30 T 10-03-2017 IPR019672 Protein of unknown function DUF2627 RG49_RS13055 fe3e07d970ca830a34d91a3fa7e4f9e2 102 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 2.0E-29 T 10-03-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 RG49_RS13055 fe3e07d970ca830a34d91a3fa7e4f9e2 102 Gene3D G3DSA:2.30.30.100 1 74 4.5E-38 T 10-03-2017 RG49_RS13055 fe3e07d970ca830a34d91a3fa7e4f9e2 102 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.396 T 10-03-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 RG49_RS13055 fe3e07d970ca830a34d91a3fa7e4f9e2 102 SUPERFAMILY SSF50182 7 69 4.04E-24 T 10-03-2017 IPR010920 LSM domain RG49_RS10210 7e76216cbe691937401a5dd2448a79c7 142 Pfam PF07409 Phage protein GP46 21 126 6.6E-36 T 10-03-2017 IPR010877 Bacteriophage Mu, Gp46 RG49_RS08195 791f92ae0a9d676a1175a548eee6ddb5 271 SMART SM00382 32 229 7.4E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS08195 791f92ae0a9d676a1175a548eee6ddb5 271 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS08195 791f92ae0a9d676a1175a548eee6ddb5 271 Gene3D G3DSA:3.40.50.300 8 241 5.9E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08195 791f92ae0a9d676a1175a548eee6ddb5 271 Pfam PF00005 ABC transporter 24 171 4.1E-34 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS08195 791f92ae0a9d676a1175a548eee6ddb5 271 SUPERFAMILY SSF52540 8 233 1.08E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23400 8efe6da383faae491dd79595a89ad2bd 169 Gene3D G3DSA:2.60.40.1090 44 169 5.2E-9 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS23400 8efe6da383faae491dd79595a89ad2bd 169 Pfam PF00419 Fimbrial protein 42 169 6.4E-20 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS23400 8efe6da383faae491dd79595a89ad2bd 169 SUPERFAMILY SSF49401 43 169 7.46E-26 T 10-03-2017 IPR008966 Adhesion domain RG49_RS01500 166e04931ad678bcd8588b541710f9c1 348 Gene3D G3DSA:3.20.20.70 8 347 7.1E-147 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS01500 166e04931ad678bcd8588b541710f9c1 348 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 348 1.4E-177 T 10-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 RG49_RS01500 166e04931ad678bcd8588b541710f9c1 348 Pfam PF00793 DAHP synthetase I family 43 336 5.6E-110 T 10-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS01500 166e04931ad678bcd8588b541710f9c1 348 PIRSF PIRSF001361 1 348 1.2E-158 T 10-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 RG49_RS01500 166e04931ad678bcd8588b541710f9c1 348 SUPERFAMILY SSF51569 7 347 5.55E-132 T 10-03-2017 RG49_RS17755 60cc16d3867fddc59ceac02648228f66 268 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 73 82 - T 10-03-2017 IPR024002 Formate/nitrite transporter, conserved site RG49_RS17755 60cc16d3867fddc59ceac02648228f66 268 Pfam PF01226 Formate/nitrite transporter 20 247 6.9E-57 T 10-03-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 RG49_RS17755 60cc16d3867fddc59ceac02648228f66 268 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 157 167 - T 10-03-2017 IPR024002 Formate/nitrite transporter, conserved site RG49_RS17755 60cc16d3867fddc59ceac02648228f66 268 Gene3D G3DSA:1.20.1080.10 24 250 2.7E-60 T 10-03-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 RG49_RS17755 60cc16d3867fddc59ceac02648228f66 268 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 21 250 1.5E-84 T 10-03-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 RG49_RS17470 9a638c004131c6a480025772a42b0157 339 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 185 274 3.3E-9 T 10-03-2017 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain RG49_RS17470 9a638c004131c6a480025772a42b0157 339 SUPERFAMILY SSF52913 185 279 2.88E-22 T 10-03-2017 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain RG49_RS17470 9a638c004131c6a480025772a42b0157 339 SUPERFAMILY SSF55205 275 337 7.19E-10 T 10-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 RG49_RS17470 9a638c004131c6a480025772a42b0157 339 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 5 339 38.13 T 10-03-2017 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 RG49_RS17470 9a638c004131c6a480025772a42b0157 339 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 158 168 - T 10-03-2017 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site RG49_RS17470 9a638c004131c6a480025772a42b0157 339 Gene3D G3DSA:3.65.10.20 275 334 1.2E-88 T 10-03-2017 IPR023797 RNA 3'-terminal phosphate cyclase domain RG49_RS17470 9a638c004131c6a480025772a42b0157 339 Gene3D G3DSA:3.65.10.20 5 178 1.2E-88 T 10-03-2017 IPR023797 RNA 3'-terminal phosphate cyclase domain RG49_RS17470 9a638c004131c6a480025772a42b0157 339 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 6 325 6.3E-120 T 10-03-2017 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 RG49_RS17470 9a638c004131c6a480025772a42b0157 339 Gene3D G3DSA:3.30.360.20 186 274 1.4E-37 T 10-03-2017 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain RG49_RS17470 9a638c004131c6a480025772a42b0157 339 SUPERFAMILY SSF55205 5 184 1.5E-64 T 10-03-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 RG49_RS17470 9a638c004131c6a480025772a42b0157 339 Pfam PF01137 RNA 3'-terminal phosphate cyclase 13 326 2.1E-78 T 10-03-2017 IPR023797 RNA 3'-terminal phosphate cyclase domain RG49_RS17470 9a638c004131c6a480025772a42b0157 339 PIRSF PIRSF005378 2 339 8.3E-116 T 10-03-2017 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 RG49_RS19420 941ca9aeac07a0f01c7a8d98afa84f8f 487 Pfam PF00939 Sodium:sulfate symporter transmembrane region 5 486 1.4E-186 T 10-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 RG49_RS19420 941ca9aeac07a0f01c7a8d98afa84f8f 487 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 24 482 2.0E-169 T 10-03-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 RG49_RS19420 941ca9aeac07a0f01c7a8d98afa84f8f 487 PIRSF PIRSF002457 2 487 2.2E-133 T 10-03-2017 IPR030676 Citrate carrier CitT-related RG49_RS17215 1b834039054126a30266a06018e5a481 221 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 12 205 8.3E-69 T 10-03-2017 IPR003744 Protein of unknown function DUF165 RG49_RS17215 1b834039054126a30266a06018e5a481 221 Pfam PF02592 Putative vitamin uptake transporter 43 199 6.0E-37 T 10-03-2017 IPR003744 Protein of unknown function DUF165 RG49_RS02425 f7268ebf189f3ece92ceb5dce8b311aa 247 Gene3D G3DSA:2.60.40.1080 159 243 1.7E-9 T 10-03-2017 RG49_RS02425 f7268ebf189f3ece92ceb5dce8b311aa 247 SMART SM00635 160 240 2.0E-19 T 10-03-2017 IPR003343 Bacterial Ig-like, group 2 RG49_RS02425 f7268ebf189f3ece92ceb5dce8b311aa 247 SUPERFAMILY SSF49373 157 241 7.85E-7 T 10-03-2017 IPR008964 Invasin/intimin cell-adhesion fragments RG49_RS02425 f7268ebf189f3ece92ceb5dce8b311aa 247 Pfam PF02368 Bacterial Ig-like domain (group 2) 161 238 9.5E-12 T 10-03-2017 IPR003343 Bacterial Ig-like, group 2 RG49_RS02425 f7268ebf189f3ece92ceb5dce8b311aa 247 Pfam PF16461 Lambda phage tail tube protein, TTP 2 154 3.6E-79 T 10-03-2017 IPR032494 Lambda phage tail tube protein RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 Pfam PF07687 Peptidase dimerisation domain 183 282 2.9E-17 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 Pfam PF01546 Peptidase family M20/M25/M40 78 395 1.4E-23 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 TIGRFAM TIGR03526 selenium_YgeY: putative selenium metabolism hydrolase 8 400 5.5E-218 T 10-03-2017 IPR017706 Peptidase M20/DapE, YgeY RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 SUPERFAMILY SSF55031 186 282 4.64E-13 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 10-03-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 SUPERFAMILY SSF53187 10 185 7.54E-54 T 10-03-2017 RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 SUPERFAMILY SSF53187 316 399 7.54E-54 T 10-03-2017 RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 Gene3D G3DSA:3.30.70.360 193 282 6.6E-15 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 Gene3D G3DSA:3.40.630.10 14 192 1.4E-54 T 10-03-2017 RG49_RS20550 56ef52fc84e708556588dd43eb465591 403 Gene3D G3DSA:3.40.630.10 311 395 1.4E-54 T 10-03-2017 RG49_RS03415 697c3d0cb0d7d715ab250a6da9e952d0 140 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 130 8.0E-42 T 10-03-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 RG49_RS03415 697c3d0cb0d7d715ab250a6da9e952d0 140 Pfam PF03061 Thioesterase superfamily 49 123 7.0E-21 T 10-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 RG49_RS03415 697c3d0cb0d7d715ab250a6da9e952d0 140 SUPERFAMILY SSF54637 5 131 1.94E-31 T 10-03-2017 IPR029069 HotDog domain RG49_RS03415 697c3d0cb0d7d715ab250a6da9e952d0 140 Gene3D G3DSA:3.10.129.10 3 134 4.2E-51 T 10-03-2017 IPR029069 HotDog domain RG49_RS03415 697c3d0cb0d7d715ab250a6da9e952d0 140 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 19 132 3.4E-53 T 10-03-2017 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 RG49_RS25080 c16cd228e86a446cbbcf5f47380e7c6a 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 238 1.8E-80 T 10-03-2017 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 RG49_RS25080 c16cd228e86a446cbbcf5f47380e7c6a 245 Gene3D G3DSA:3.20.20.70 1 243 3.7E-79 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS25080 c16cd228e86a446cbbcf5f47380e7c6a 245 SUPERFAMILY SSF51366 1 242 6.39E-66 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS25080 c16cd228e86a446cbbcf5f47380e7c6a 245 Pfam PF00977 Histidine biosynthesis protein 1 234 7.9E-76 T 10-03-2017 IPR006062 Histidine biosynthesis GO:0000105 RG49_RS25080 c16cd228e86a446cbbcf5f47380e7c6a 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 241 35.811 T 10-03-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 RG49_RS01815 675fa70156ccc6aab6ccbfa67ecfaf15 173 SUPERFAMILY SSF49329 23 173 2.62E-46 T 10-03-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01815 675fa70156ccc6aab6ccbfa67ecfaf15 173 Gene3D G3DSA:2.60.40.200 23 173 5.0E-46 T 10-03-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01815 675fa70156ccc6aab6ccbfa67ecfaf15 173 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 34 172 8.4E-31 T 10-03-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS01815 675fa70156ccc6aab6ccbfa67ecfaf15 173 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 161 172 - T 10-03-2017 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 Gene3D G3DSA:1.10.10.10 5 89 4.4E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 Pfam PF03466 LysR substrate binding domain 134 299 2.5E-9 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 5.6E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 SUPERFAMILY SSF46785 8 91 3.16E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 SUPERFAMILY SSF53850 115 298 1.68E-19 T 10-03-2017 RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 9.4E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 9.4E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 9.4E-5 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS08110 6cc2134a34b3420e90011cbc846c2255 300 Gene3D G3DSA:3.40.190.10 176 271 2.0E-8 T 10-03-2017 RG49_RS10365 2faf1b94c8a9a8e3b53c12e5bf6d83f3 129 Gene3D G3DSA:3.30.1330.70 1 123 2.5E-35 T 10-03-2017 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 RG49_RS10365 2faf1b94c8a9a8e3b53c12e5bf6d83f3 129 SUPERFAMILY SSF103084 2 120 8.24E-30 T 10-03-2017 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 RG49_RS10365 2faf1b94c8a9a8e3b53c12e5bf6d83f3 129 Pfam PF05866 Endodeoxyribonuclease RusA 6 118 2.2E-17 T 10-03-2017 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 RG49_RS10365 2faf1b94c8a9a8e3b53c12e5bf6d83f3 129 PIRSF PIRSF001007 1 125 4.9E-49 T 10-03-2017 IPR016281 Crossover junction endodeoxyribonuclease, RusA GO:0008821 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 SUPERFAMILY SSF50156 256 352 1.97E-20 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 SMART SM00228 257 339 2.2E-10 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 Gene3D G3DSA:2.40.10.10 148 258 1.7E-38 T 10-03-2017 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 SUPERFAMILY SSF50494 47 254 1.68E-60 T 10-03-2017 IPR009003 Peptidase S1, PA clan RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 Gene3D G3DSA:2.40.10.10 34 138 1.9E-31 T 10-03-2017 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 PRINTS PR00834 HtrA/DegQ protease family signature 151 175 2.4E-47 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 PRINTS PR00834 HtrA/DegQ protease family signature 208 225 2.4E-47 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 PRINTS PR00834 HtrA/DegQ protease family signature 186 203 2.4E-47 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 PRINTS PR00834 HtrA/DegQ protease family signature 89 101 2.4E-47 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 PRINTS PR00834 HtrA/DegQ protease family signature 297 309 2.4E-47 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 PRINTS PR00834 HtrA/DegQ protease family signature 110 130 2.4E-47 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 TIGRFAM TIGR02038 protease_degS: periplasmic serine peptidase DegS 2 352 8.2E-183 T 10-03-2017 IPR011783 Peptidase S1C, DegS GO:0004252|GO:0006508 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 Pfam PF13365 Trypsin-like peptidase domain 80 215 1.7E-28 T 10-03-2017 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 Gene3D G3DSA:2.30.42.10 259 353 1.9E-26 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS18445 d93ed33f63ae8ebec2b3f08782629cbc 355 Pfam PF13180 PDZ domain 279 347 4.4E-13 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS16250 d81661e1b38bb1dd15d6ed2325b21225 265 PIRSF PIRSF037318 1 265 6.0E-168 T 10-03-2017 IPR017172 Lipopolysaccharide core heptose(I) kinase rfaP GO:0009103|GO:0016301 RG49_RS16250 d81661e1b38bb1dd15d6ed2325b21225 265 SUPERFAMILY SSF56112 34 233 3.77E-8 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS16250 d81661e1b38bb1dd15d6ed2325b21225 265 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 20 230 3.9E-66 T 10-03-2017 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 RG49_RS05205 53fd3b3ffa801fe18b080a169dc0e83d 173 Pfam PF02620 Uncharacterized ACR, COG1399 61 171 1.6E-19 T 10-03-2017 IPR003772 Protein of unknown function DUF177 RG49_RS04060 dbf4deef617413556245e11f81a454be 472 Gene3D G3DSA:3.10.20.70 25 136 3.9E-9 T 10-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS04060 dbf4deef617413556245e11f81a454be 472 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 271 286 - T 10-03-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 RG49_RS04060 dbf4deef617413556245e11f81a454be 472 Pfam PF00120 Glutamine synthetase, catalytic domain 134 467 1.5E-102 T 10-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS04060 dbf4deef617413556245e11f81a454be 472 SMART SM01230 133 390 4.2E-94 T 10-03-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS04060 dbf4deef617413556245e11f81a454be 472 SUPERFAMILY SSF55931 134 469 1.05E-95 T 10-03-2017 RG49_RS04060 dbf4deef617413556245e11f81a454be 472 SUPERFAMILY SSF54368 25 132 1.31E-8 T 10-03-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 RG49_RS04060 dbf4deef617413556245e11f81a454be 472 Gene3D G3DSA:3.30.590.10 137 458 1.7E-87 T 10-03-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 RG49_RS06480 c4c2c36a93761ac1f638407579790e2f 281 SUPERFAMILY SSF161098 8 266 2.9E-50 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06480 c4c2c36a93761ac1f638407579790e2f 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 273 3.1E-14 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06480 c4c2c36a93761ac1f638407579790e2f 281 Gene3D G3DSA:1.10.3720.10 11 270 5.0E-57 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24690 9603fc285a71a96412b38a50df38f69c 334 Pfam PF03747 ADP-ribosylglycohydrolase 8 302 3.4E-61 T 10-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 RG49_RS24690 9603fc285a71a96412b38a50df38f69c 334 SUPERFAMILY SSF101478 3 326 2.09E-68 T 10-03-2017 IPR005502 ADP-ribosylation/Crystallin J1 RG49_RS04745 bbb3d5be73690fd3d4a5747d85eea991 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 52 62 5.2E-12 T 10-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 RG49_RS04745 bbb3d5be73690fd3d4a5747d85eea991 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 63 74 5.2E-12 T 10-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 RG49_RS04745 bbb3d5be73690fd3d4a5747d85eea991 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 91 103 5.2E-12 T 10-03-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 RG49_RS04745 bbb3d5be73690fd3d4a5747d85eea991 139 Gene3D G3DSA:2.10.109.10 25 138 3.6E-48 T 10-03-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain RG49_RS04745 bbb3d5be73690fd3d4a5747d85eea991 139 SUPERFAMILY SSF51306 13 135 2.09E-34 T 10-03-2017 IPR015927 Peptidase S24/S26A/S26B/S26C RG49_RS04745 bbb3d5be73690fd3d4a5747d85eea991 139 Pfam PF00717 Peptidase S24-like 57 120 1.7E-11 T 10-03-2017 IPR019759 Peptidase S24/S26A/S26B RG49_RS12195 2c750571503354285254536378bc61ea 488 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 4 487 4.4E-223 T 10-03-2017 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 RG49_RS12195 2c750571503354285254536378bc61ea 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS12195 2c750571503354285254536378bc61ea 488 Gene3D G3DSA:3.40.309.10 258 449 8.6E-68 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS12195 2c750571503354285254536378bc61ea 488 SUPERFAMILY SSF53720 3 480 1.06E-166 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS12195 2c750571503354285254536378bc61ea 488 Pfam PF00171 Aldehyde dehydrogenase family 17 474 3.6E-171 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS12195 2c750571503354285254536378bc61ea 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS12195 2c750571503354285254536378bc61ea 488 Gene3D G3DSA:3.40.605.10 2 257 2.7E-98 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS13510 45106330fdbb9aa870588b2432313cd6 185 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 2 176 34.55 T 10-03-2017 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 RG49_RS13510 45106330fdbb9aa870588b2432313cd6 185 Pfam PF13238 AAA domain 6 139 1.4E-9 T 10-03-2017 RG49_RS13510 45106330fdbb9aa870588b2432313cd6 185 SMART SM00072 2 179 2.8E-36 T 10-03-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit RG49_RS13510 45106330fdbb9aa870588b2432313cd6 185 Gene3D G3DSA:3.40.50.300 73 177 2.5E-15 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13510 45106330fdbb9aa870588b2432313cd6 185 Gene3D G3DSA:3.40.50.300 2 25 2.5E-15 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13510 45106330fdbb9aa870588b2432313cd6 185 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 3 178 2.9E-74 T 10-03-2017 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 RG49_RS13510 45106330fdbb9aa870588b2432313cd6 185 SUPERFAMILY SSF52540 3 178 5.71E-33 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS10080 e192aea83294e0bfdd3eda440e71cb79 83 Gene3D G3DSA:1.10.10.60 8 83 1.0E-22 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS10080 e192aea83294e0bfdd3eda440e71cb79 83 Pfam PF01527 Transposase 4 70 9.4E-19 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS10080 e192aea83294e0bfdd3eda440e71cb79 83 SUPERFAMILY SSF46689 1 83 3.23E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS08575 a5cd85edc13a10f232c936fa89778959 236 PRINTS PR00394 RHS protein signature 39 59 4.0E-29 T 10-03-2017 IPR001826 RHS protein RG49_RS08575 a5cd85edc13a10f232c936fa89778959 236 PRINTS PR00394 RHS protein signature 15 30 4.0E-29 T 10-03-2017 IPR001826 RHS protein RG49_RS08575 a5cd85edc13a10f232c936fa89778959 236 PRINTS PR00394 RHS protein signature 62 81 4.0E-29 T 10-03-2017 IPR001826 RHS protein RG49_RS08575 a5cd85edc13a10f232c936fa89778959 236 Pfam PF03527 RHS protein 2 26 6.8E-8 T 10-03-2017 IPR001826 RHS protein RG49_RS08575 a5cd85edc13a10f232c936fa89778959 236 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 17 94 7.7E-25 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 321 4.8E-164 T 10-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 321 157.267 T 10-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 Gene3D G3DSA:3.20.20.70 55 312 1.2E-71 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 PIRSF PIRSF005963 2 321 3.2E-131 T 10-03-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 Pfam PF04055 Radical SAM superfamily 91 251 1.1E-14 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 SUPERFAMILY SSF102114 52 316 8.76E-68 T 10-03-2017 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 SMART SM00729 84 293 1.9E-15 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS07975 723afa78dd8cb0f4392bbdc68d14adc4 321 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 25 73 9.4E-7 T 10-03-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 SUPERFAMILY SSF111364 32 294 1.2E-89 T 10-03-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 Gene3D G3DSA:2.40.230.20 25 294 4.7E-106 T 10-03-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 32 294 3.1E-85 T 10-03-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 89 110 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 55 79 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 270 293 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 115 135 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 240 259 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 182 205 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 28 50 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS09075 ed1b89a738bb5f7ee793c8ae2e770053 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 150 175 2.7E-115 T 10-03-2017 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 SUPERFAMILY SSF69336 1211 1465 5.36E-88 T 10-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Pfam PF00310 Glutamine amidotransferases class-II 12 425 8.0E-177 T 10-03-2017 IPR017932 Glutamine amidotransferase type 2 domain RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Gene3D G3DSA:3.20.20.70 437 776 1.2E-101 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 SUPERFAMILY SSF56235 12 429 2.63E-149 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Gene3D G3DSA:3.20.20.70 811 1198 9.2E-163 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 SUPERFAMILY SSF51395 434 1191 2.34E-248 T 10-03-2017 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Gene3D G3DSA:2.160.20.60 1211 1465 9.3E-97 T 10-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Gene3D G3DSA:3.60.20.10 12 433 2.4E-171 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Pfam PF04898 Glutamate synthase central domain 457 737 3.2E-105 T 10-03-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Pfam PF01645 Conserved region in glutamate synthase 793 1156 4.0E-158 T 10-03-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 RG49_RS18570 8d3ca885fcf8569e84aca6864ab563a1 1486 Pfam PF01493 GXGXG motif 1236 1418 1.7E-74 T 10-03-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 SMART SM00382 349 549 2.2E-13 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 SMART SM00382 41 246 4.3E-18 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 Gene3D G3DSA:3.40.50.300 312 565 9.1E-81 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 Gene3D G3DSA:3.40.50.300 12 270 1.3E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 543 575 4.3E-8 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 280 6.6E-8 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 SUPERFAMILY SSF52540 314 563 1.2E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 Pfam PF00005 ABC transporter 33 196 1.1E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 Pfam PF00005 ABC transporter 341 491 1.5E-29 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06860 c08ababdcbc5df9917ef6e810faa3934 623 SUPERFAMILY SSF52540 12 268 2.66E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23880 398101ff82145b8790692a2fd357773e 299 Pfam PF04754 Putative transposase, YhgA-like 8 209 5.6E-86 T 10-03-2017 IPR006842 Transposase (putative), YhgA-like RG49_RS23880 398101ff82145b8790692a2fd357773e 299 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 295 2.3E-51 T 10-03-2017 IPR010106 Conserved hypothetical protein CHP01784 RG49_RS16005 226a1dfaacd16a6a95145bb6b2241572 181 Pfam PF13708 Domain of unknown function (DUF4942) 2 175 5.7E-52 T 10-03-2017 IPR031339 Domain of unknown function DUF4942 RG49_RS12950 67fc601402568c525e8e38c22ba634e7 354 Pfam PF13483 Beta-lactamase superfamily domain 42 281 2.2E-15 T 10-03-2017 RG49_RS12950 67fc601402568c525e8e38c22ba634e7 354 Gene3D G3DSA:3.60.15.10 1 336 2.7E-130 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS12950 67fc601402568c525e8e38c22ba634e7 354 Hamap MF_01266 Probable L-ascorbate-6-phosphate lactonase UlaG [ulaG]. 1 354 99.661 T 10-03-2017 IPR023951 L-ascorbate-6-phosphate lactonase UlaG GO:0019854|GO:0030145|GO:0035460 RG49_RS12950 67fc601402568c525e8e38c22ba634e7 354 SUPERFAMILY SSF56281 36 302 1.11E-26 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS11095 8f25056c96b18ceaa490d3a2fe084fe9 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 5 174 22.352 T 10-03-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 RG49_RS11095 8f25056c96b18ceaa490d3a2fe084fe9 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 6 174 9.9E-45 T 10-03-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 RG49_RS11095 8f25056c96b18ceaa490d3a2fe084fe9 176 SUPERFAMILY SSF55144 6 174 8.89E-45 T 10-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase RG49_RS11095 8f25056c96b18ceaa490d3a2fe084fe9 176 Gene3D G3DSA:3.90.1140.10 5 176 4.6E-50 T 10-03-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase RG49_RS11095 8f25056c96b18ceaa490d3a2fe084fe9 176 Pfam PF02834 LigT like Phosphoesterase 92 164 1.1E-7 T 10-03-2017 IPR014051 Phosphoesterase, HXTX RG49_RS11095 8f25056c96b18ceaa490d3a2fe084fe9 176 Pfam PF02834 LigT like Phosphoesterase 11 89 9.7E-13 T 10-03-2017 IPR014051 Phosphoesterase, HXTX RG49_RS01920 79743816d85a4051a102a24dd65eee7a 146 Pfam PF10754 Protein of unknown function (DUF2569) 6 144 1.5E-39 T 10-03-2017 IPR019690 Protein of unknown function DUF2569 RG49_RS16990 3ebfa9baa4ef7004cb2d24c105fbd7db 110 Hamap MF_00946 Acid stress chaperone HdeA [hdeA]. 1 106 34.938 T 10-03-2017 IPR024972 HNS-dependent expression A GO:0030288|GO:0071468 RG49_RS16990 3ebfa9baa4ef7004cb2d24c105fbd7db 110 Pfam PF06411 HdeA/HdeB family 12 96 5.0E-27 T 10-03-2017 IPR010486 HNS-dependent expression A/B RG49_RS16990 3ebfa9baa4ef7004cb2d24c105fbd7db 110 ProDom PD065392 HDEA PRECURSOR SIGNAL PERIPLASMIC 3D-STRUCTURE DIRECT 10K-S SEQUENCING 38 108 1.0E-34 T 10-03-2017 IPR024972 HNS-dependent expression A GO:0030288|GO:0071468 RG49_RS16990 3ebfa9baa4ef7004cb2d24c105fbd7db 110 Gene3D G3DSA:1.10.890.10 22 110 4.1E-42 T 10-03-2017 IPR010486 HNS-dependent expression A/B RG49_RS16990 3ebfa9baa4ef7004cb2d24c105fbd7db 110 PIRSF PIRSF009564 1 107 8.0E-60 T 10-03-2017 IPR024972 HNS-dependent expression A GO:0030288|GO:0071468 RG49_RS16990 3ebfa9baa4ef7004cb2d24c105fbd7db 110 SUPERFAMILY SSF47752 30 108 1.44E-43 T 10-03-2017 IPR024972 HNS-dependent expression A GO:0030288|GO:0071468 RG49_RS23080 40a7020ae00c1ec205d5229a05bdacc3 72 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 68 4.0E-25 T 10-03-2017 IPR024530 Putative quorum-sensing-regulated virulence factor RG49_RS23080 40a7020ae00c1ec205d5229a05bdacc3 72 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 3 68 2.4E-29 T 10-03-2017 IPR024530 Putative quorum-sensing-regulated virulence factor RG49_RS10685 a1473dcb16cb29cff484f4ab9b7fb99f 247 Pfam PF11319 Type VI secretion system VasI, EvfG, VC_A0118 57 244 8.8E-52 T 10-03-2017 IPR017738 Type VI secretion system-associated, VCA0118 RG49_RS10685 a1473dcb16cb29cff484f4ab9b7fb99f 247 TIGRFAM TIGR03360 VI_minor_1: type VI secretion-associated protein, VC_A0118 family 55 244 2.3E-77 T 10-03-2017 IPR017738 Type VI secretion system-associated, VCA0118 RG49_RS04165 c33fda3f705d63a451a8d4eee56752db 102 Pfam PF06305 Protein of unknown function (DUF1049) 23 85 2.6E-21 T 10-03-2017 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 RG49_RS04165 c33fda3f705d63a451a8d4eee56752db 102 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 1 94 22.825 T 10-03-2017 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 RG49_RS02430 68bba8857485218c3cb1aad96dc971f9 128 Pfam PF06894 Bacteriophage lambda tail assembly chaperone, TAC, protein G 1 121 8.0E-40 T 10-03-2017 IPR010027 Bacteriophage lambda, GpG, minor tail RG49_RS02430 68bba8857485218c3cb1aad96dc971f9 128 TIGRFAM TIGR01674 phage_lambda_G: phage minor tail protein G 1 128 1.8E-55 T 10-03-2017 IPR010027 Bacteriophage lambda, GpG, minor tail RG49_RS23705 5472dc539785dfa1047e5dc5e1ab8e7e 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 337 356 1.1E-37 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23705 5472dc539785dfa1047e5dc5e1ab8e7e 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 249 273 1.1E-37 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23705 5472dc539785dfa1047e5dc5e1ab8e7e 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 1.1E-37 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23705 5472dc539785dfa1047e5dc5e1ab8e7e 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 1.1E-37 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23705 5472dc539785dfa1047e5dc5e1ab8e7e 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 389 415 1.1E-37 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23705 5472dc539785dfa1047e5dc5e1ab8e7e 509 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 3 499 4.5E-186 T 10-03-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23705 5472dc539785dfa1047e5dc5e1ab8e7e 509 Pfam PF00361 Proton-conducting membrane transporter 134 430 4.8E-70 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS04755 d73848551f0d39113c9ab657dde8811a 153 Pfam PF03692 Putative zinc- or iron-chelating domain 29 97 2.8E-8 T 10-03-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein RG49_RS04755 d73848551f0d39113c9ab657dde8811a 153 PIRSF PIRSF006173 3 150 5.1E-69 T 10-03-2017 IPR008228 Uncharacterised conserved protein UCP006173 RG49_RS04755 d73848551f0d39113c9ab657dde8811a 153 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 7 150 42.999 T 10-03-2017 IPR008228 Uncharacterised conserved protein UCP006173 RG49_RS08680 955e9d6870bf40a4e65d45a752744566 264 Pfam PF01963 TraB family 30 264 4.1E-41 T 10-03-2017 IPR002816 Pheromone shutdown, TraB RG49_RS13975 1717022bae5763ebfa317e2ebce04a07 274 SMART SM00346 24 114 5.8E-38 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS13975 1717022bae5763ebfa317e2ebce04a07 274 SUPERFAMILY SSF55781 95 271 7.19E-50 T 10-03-2017 IPR029016 GAF domain-like RG49_RS13975 1717022bae5763ebfa317e2ebce04a07 274 Gene3D G3DSA:3.30.450.40 96 271 2.3E-58 T 10-03-2017 IPR029016 GAF domain-like RG49_RS13975 1717022bae5763ebfa317e2ebce04a07 274 Gene3D G3DSA:1.10.10.10 16 85 2.2E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13975 1717022bae5763ebfa317e2ebce04a07 274 SUPERFAMILY SSF46785 24 97 2.37E-15 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13975 1717022bae5763ebfa317e2ebce04a07 274 Pfam PF01614 Bacterial transcriptional regulator 145 267 1.3E-41 T 10-03-2017 IPR014757 Transcription regulator IclR, C-terminal RG49_RS13975 1717022bae5763ebfa317e2ebce04a07 274 Pfam PF09339 IclR helix-turn-helix domain 26 76 1.1E-18 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS10530 f041b62ccc44b898603b9daac0d4a225 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 56 4.2E-36 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS10530 f041b62ccc44b898603b9daac0d4a225 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 19 35 4.2E-36 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS10530 f041b62ccc44b898603b9daac0d4a225 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 119 133 4.2E-36 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS10530 f041b62ccc44b898603b9daac0d4a225 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 68 85 4.2E-36 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS10530 f041b62ccc44b898603b9daac0d4a225 579 Pfam PF00771 FHIPEP family 9 570 5.3E-188 T 10-03-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 RG49_RS10530 f041b62ccc44b898603b9daac0d4a225 579 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 24 47 - T 10-03-2017 IPR025505 FHIPEP conserved site RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 149 171 8.2E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 8.2E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 279 298 8.2E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 95 117 8.2E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 8.2E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 250 267 8.2E-73 T 10-03-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 Pfam PF00267 Gram-negative porin 27 376 1.4E-148 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 328 344 - T 10-03-2017 IPR013793 Porin, Gram-negative type, conserved site RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 Gene3D G3DSA:2.40.160.10 22 376 4.1E-101 T 10-03-2017 IPR023614 Porin domain RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 151 162 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 244 256 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 328 345 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 95 105 1.3E-18 T 10-03-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 RG49_RS24050 82f9ef6562c464a28459f2f96642e727 376 SUPERFAMILY SSF56935 22 376 3.66E-81 T 10-03-2017 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 SMART SM00876 220 312 6.8E-49 T 10-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 220 310 1.3E-20 T 10-03-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 TIGRFAM TIGR00433 bioB: biotin synthase 14 310 2.3E-125 T 10-03-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 Pfam PF04055 Radical SAM superfamily 50 203 6.2E-18 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 SUPERFAMILY SSF102114 6 313 2.62E-95 T 10-03-2017 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 Gene3D G3DSA:3.20.20.70 6 314 1.3E-107 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 PIRSF PIRSF001619 1 319 7.8E-141 T 10-03-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 Hamap MF_01694 Biotin synthase [bioB]. 5 313 41.81 T 10-03-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 RG49_RS07155 ecbf75df6acdc7918e9a9eed66c72b8d 346 SMART SM00729 43 255 4.3E-43 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS05120 c65ae3b77f5a90c598beb8fb073593d0 213 Pfam PF13036 Peptidoglycan-synthase activator LpoB 10 210 8.1E-56 T 10-03-2017 IPR014094 Penicillin-binding protein activator LpoB RG49_RS05120 c65ae3b77f5a90c598beb8fb073593d0 213 Hamap MF_01889 Penicillin-binding protein activator LpoB [lpoB]. 4 211 35.098 T 10-03-2017 IPR014094 Penicillin-binding protein activator LpoB RG49_RS05120 c65ae3b77f5a90c598beb8fb073593d0 213 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 6 212 2.9E-65 T 10-03-2017 IPR014094 Penicillin-binding protein activator LpoB RG49_RS18745 a04f362abdb231dcff8b802527688b2f 209 Pfam PF01728 FtsJ-like methyltransferase 31 206 1.6E-58 T 10-03-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 RG49_RS18745 a04f362abdb231dcff8b802527688b2f 209 Gene3D G3DSA:3.40.50.150 1 208 7.3E-74 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS18745 a04f362abdb231dcff8b802527688b2f 209 SUPERFAMILY SSF53335 31 208 1.09E-43 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS18745 a04f362abdb231dcff8b802527688b2f 209 TIGRFAM TIGR00438 rrmJ: ribosomal RNA large subunit methyltransferase J 20 206 4.9E-97 T 10-03-2017 IPR004512 Ribosomal RNA methyltransferase E, gammaproteobacteria GO:0006364|GO:0016436 KEGG: 00564+2.1.1.16 RG49_RS18745 a04f362abdb231dcff8b802527688b2f 209 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 11 207 27.794 T 10-03-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 RG49_RS18745 a04f362abdb231dcff8b802527688b2f 209 PIRSF PIRSF005461 1 209 8.8E-83 T 10-03-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 RG49_RS20425 bdb84d882dd9a33c97d64ebed39a9242 173 PIRSF PIRSF038996 1 172 2.3E-55 T 10-03-2017 IPR010086 Flavodoxin, long chain GO:0010181 RG49_RS20425 bdb84d882dd9a33c97d64ebed39a9242 173 TIGRFAM TIGR01752 flav_long: flavodoxin 3 168 1.8E-69 T 10-03-2017 IPR010086 Flavodoxin, long chain GO:0010181 RG49_RS20425 bdb84d882dd9a33c97d64ebed39a9242 173 Gene3D G3DSA:3.40.50.360 1 168 5.9E-56 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS20425 bdb84d882dd9a33c97d64ebed39a9242 173 SUPERFAMILY SSF52218 1 168 1.51E-46 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS20425 bdb84d882dd9a33c97d64ebed39a9242 173 Pfam PF00258 Flavodoxin 5 160 4.0E-28 T 10-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 RG49_RS20425 bdb84d882dd9a33c97d64ebed39a9242 173 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 10-03-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 RG49_RS24365 c004b46ac0d958685cc3dfd0e52110c7 349 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 14 348 1.8E-171 T 10-03-2017 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 RG49_RS24365 c004b46ac0d958685cc3dfd0e52110c7 349 Pfam PF03601 Conserved hypothetical protein 698 18 326 1.3E-117 T 10-03-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 RG49_RS17390 ec380fe5bf8f4b6aa485be155609abc4 175 SUPERFAMILY SSF52540 4 172 6.47E-26 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17390 ec380fe5bf8f4b6aa485be155609abc4 175 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 11 173 8.4E-73 T 10-03-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 RG49_RS17390 ec380fe5bf8f4b6aa485be155609abc4 175 Gene3D G3DSA:3.40.50.300 4 172 7.9E-71 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17390 ec380fe5bf8f4b6aa485be155609abc4 175 Pfam PF01202 Shikimate kinase 17 171 2.5E-12 T 10-03-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 8 482 9.3E-186 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 206 223 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 428 444 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 450 472 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 363 381 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PRINTS PR00934 X-His dipeptidase (M25) signature 251 270 2.9E-103 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 PIRSF PIRSF016599 1 485 6.6E-215 T 10-03-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 Pfam PF07687 Peptidase dimerisation domain 209 293 7.8E-8 T 10-03-2017 IPR011650 Peptidase M20, dimerisation domain RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 SUPERFAMILY SSF53187 397 482 6.01E-66 T 10-03-2017 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 SUPERFAMILY SSF53187 10 182 6.01E-66 T 10-03-2017 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 Gene3D G3DSA:3.40.630.10 3 181 4.7E-111 T 10-03-2017 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 Gene3D G3DSA:3.40.630.10 397 483 4.7E-111 T 10-03-2017 RG49_RS10490 514af639c31e8b9b3bd9ffa1553c1f78 485 Pfam PF01546 Peptidase family M20/M25/M40 73 480 9.7E-21 T 10-03-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 RG49_RS18615 5bb437dfbbabba6e96122e3e5bd18614 284 PIRSF PIRSF005052 1 284 3.2E-114 T 10-03-2017 IPR005337 RapZ-like family GO:0005524 RG49_RS18615 5bb437dfbbabba6e96122e3e5bd18614 284 Pfam PF03668 P-loop ATPase protein family 1 282 2.6E-147 T 10-03-2017 IPR005337 RapZ-like family GO:0005524 RG49_RS18615 5bb437dfbbabba6e96122e3e5bd18614 284 Gene3D G3DSA:3.40.50.300 2 150 5.9E-13 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18615 5bb437dfbbabba6e96122e3e5bd18614 284 SUPERFAMILY SSF52540 2 151 5.03E-13 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18615 5bb437dfbbabba6e96122e3e5bd18614 284 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 281 41.009 T 10-03-2017 IPR005337 RapZ-like family GO:0005524 RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Gene3D G3DSA:3.40.50.300 245 331 6.5E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Gene3D G3DSA:3.40.50.300 3 110 6.5E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 443 43.828 T 10-03-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 SMART SM01086 335 434 1.3E-21 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 SUPERFAMILY SSF52540 3 441 3.83E-95 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Pfam PF07724 AAA domain (Cdc48 subfamily) 188 329 8.6E-43 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 106 6.9E-7 T 10-03-2017 IPR003959 ATPase, AAA-type, core GO:0005524 RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Gene3D G3DSA:1.10.8.10 213 243 3.3E-34 T 10-03-2017 RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Gene3D G3DSA:1.10.8.10 111 177 3.3E-34 T 10-03-2017 RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 SMART SM00382 49 332 1.3E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 443 5.1E-239 T 10-03-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 335 405 2.3E-5 T 10-03-2017 IPR019489 Clp ATPase, C-terminal RG49_RS14470 4305fb1988a41d68599001842b2345ea 443 Gene3D G3DSA:1.10.8.60 335 443 2.0E-34 T 10-03-2017 RG49_RS01385 590127badbcf03f51349813aa6afeb2f 96 ProDom PD066031 YDIZ CYTOPLASMIC STY1786 1 96 1.0E-49 T 10-03-2017 IPR020499 Uncharacterised protein family YdiZ RG49_RS01385 590127badbcf03f51349813aa6afeb2f 96 Pfam PF11080 Protein of unknown function (DUF2622) 1 93 1.6E-40 T 10-03-2017 IPR022597 Endoribonuclease GhoS GO:0004521 RG49_RS00930 a3a31d17671eca9f3cc6674aea4faab9 114 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 90 108 - T 10-03-2017 IPR019897 RidA, conserved site RG49_RS00930 a3a31d17671eca9f3cc6674aea4faab9 114 Pfam PF01042 Endoribonuclease L-PSP 4 114 1.6E-28 T 10-03-2017 IPR006175 YjgF/YER057c/UK114 family RG49_RS00930 a3a31d17671eca9f3cc6674aea4faab9 114 Gene3D G3DSA:3.30.1330.40 6 113 1.3E-20 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS00930 a3a31d17671eca9f3cc6674aea4faab9 114 SUPERFAMILY SSF55298 5 114 2.67E-27 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS01145 b72c71c4ba0b75de6c308a8ccf4a4cbe 213 SUPERFAMILY SSF52499 4 208 1.44E-54 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS01145 b72c71c4ba0b75de6c308a8ccf4a4cbe 213 Gene3D G3DSA:3.40.50.850 4 208 3.3E-66 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS01145 b72c71c4ba0b75de6c308a8ccf4a4cbe 213 Pfam PF00857 Isochorismatase family 5 207 5.2E-38 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 SUPERFAMILY SSF54862 12 125 4.18E-21 T 10-03-2017 RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 Pfam PF02754 Cysteine-rich domain 303 385 2.9E-13 T 10-03-2017 IPR004017 Cysteine-rich domain RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 Pfam PF02754 Cysteine-rich domain 170 255 5.4E-13 T 10-03-2017 IPR004017 Cysteine-rich domain RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 PIRSF PIRSF000139 5 407 1.5E-143 T 10-03-2017 IPR012257 Glycolate oxidase, iron-sulphur subunit RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 Gene3D G3DSA:1.10.1060.10 7 106 2.1E-22 T 10-03-2017 RG49_RS19910 07a02f69d8d9bd332d5c5b9ca422a886 407 Pfam PF13183 4Fe-4S dicluster domain 22 89 2.3E-12 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS05955 d4cde8ccefd4aac4b796529242bb3092 55 Hamap MF_00919 Ribosome modulation factor [rmf]. 1 55 31.965 T 10-03-2017 IPR007040 Ribosome modulation factor RG49_RS05955 d4cde8ccefd4aac4b796529242bb3092 55 Pfam PF04957 Ribosome modulation factor 1 52 1.3E-30 T 10-03-2017 IPR007040 Ribosome modulation factor RG49_RS05955 d4cde8ccefd4aac4b796529242bb3092 55 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 55 7.0E-26 T 10-03-2017 IPR007040 Ribosome modulation factor RG49_RS05955 d4cde8ccefd4aac4b796529242bb3092 55 Gene3D G3DSA:1.10.10.620 1 51 5.2E-28 T 10-03-2017 IPR023200 Ribosome modulation factor-like domain RG49_RS03470 a898d666b1d3b33a18542d1995da4920 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 271 278 - T 10-03-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 RG49_RS03470 a898d666b1d3b33a18542d1995da4920 499 Pfam PF00171 Aldehyde dehydrogenase family 33 495 6.2E-162 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03470 a898d666b1d3b33a18542d1995da4920 499 Gene3D G3DSA:3.40.309.10 286 470 3.6E-61 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS03470 a898d666b1d3b33a18542d1995da4920 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 299 310 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS03470 a898d666b1d3b33a18542d1995da4920 499 Gene3D G3DSA:3.40.605.10 19 285 2.2E-97 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS03470 a898d666b1d3b33a18542d1995da4920 499 SUPERFAMILY SSF53720 9 498 1.1E-160 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS25165 1f12ca8ea3eade2cce24231c899277d9 157 Pfam PF06445 GyrI-like small molecule binding domain 1 152 4.4E-29 T 10-03-2017 IPR029442 GyrI-like small molecule binding domain RG49_RS25165 1f12ca8ea3eade2cce24231c899277d9 157 SMART SM00871 1 153 8.2E-33 T 10-03-2017 IPR010499 Bacterial transcription activator, effector binding RG49_RS25165 1f12ca8ea3eade2cce24231c899277d9 157 SUPERFAMILY SSF55136 1 155 1.64E-43 T 10-03-2017 IPR011256 Regulatory factor, effector binding domain RG49_RS25165 1f12ca8ea3eade2cce24231c899277d9 157 Gene3D G3DSA:3.20.80.10 1 155 1.5E-54 T 10-03-2017 IPR011256 Regulatory factor, effector binding domain RG49_RS25165 1f12ca8ea3eade2cce24231c899277d9 157 Hamap MF_01896 DNA gyrase inhibitor [sbmC]. 1 155 39.323 T 10-03-2017 IPR024911 DNA gyrase inhibitor GyrI GO:0008657 RG49_RS22660 03976b836c485a5ee89901e09d2fb723 208 SUPERFAMILY SSF53271 4 206 3.02E-66 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS22660 03976b836c485a5ee89901e09d2fb723 208 Gene3D G3DSA:3.40.50.2020 2 208 5.0E-75 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS22660 03976b836c485a5ee89901e09d2fb723 208 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 8.7E-65 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS22660 03976b836c485a5ee89901e09d2fb723 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 44.829 T 10-03-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 RG49_RS22660 03976b836c485a5ee89901e09d2fb723 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 4.1E-90 T 10-03-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 RG49_RS22025 f8d0f856f4cb32d74c9e1d3c01317ac0 356 SUPERFAMILY SSF51569 8 346 1.92E-135 T 10-03-2017 RG49_RS22025 f8d0f856f4cb32d74c9e1d3c01317ac0 356 Gene3D G3DSA:3.20.20.70 10 348 2.2E-154 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS22025 f8d0f856f4cb32d74c9e1d3c01317ac0 356 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 8 350 6.7E-176 T 10-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 RG49_RS22025 f8d0f856f4cb32d74c9e1d3c01317ac0 356 PIRSF PIRSF001361 1 354 7.6E-165 T 10-03-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 RG49_RS22025 f8d0f856f4cb32d74c9e1d3c01317ac0 356 Pfam PF00793 DAHP synthetase I family 39 340 9.7E-109 T 10-03-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS10905 00529aad8c9fd81e045d4e1d8f4a6e2d 382 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 6 382 43.853 T 10-03-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS10905 00529aad8c9fd81e045d4e1d8f4a6e2d 382 Pfam PF02684 Lipid-A-disaccharide synthetase 9 377 8.6E-159 T 10-03-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS10905 00529aad8c9fd81e045d4e1d8f4a6e2d 382 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 1 380 5.5E-194 T 10-03-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 RG49_RS10905 00529aad8c9fd81e045d4e1d8f4a6e2d 382 Gene3D G3DSA:3.40.50.2000 172 358 3.0E-6 T 10-03-2017 RG49_RS10905 00529aad8c9fd81e045d4e1d8f4a6e2d 382 SUPERFAMILY SSF53756 9 361 1.63E-29 T 10-03-2017 RG49_RS23510 6f45c2901a67422984252b26c0d8a19b 220 Hamap MF_02022 Cell division protein DedD [dedD]. 10 219 24.516 T 10-03-2017 IPR032898 Cell division protein DedD GO:0030428|GO:0032506 RG49_RS23510 6f45c2901a67422984252b26c0d8a19b 220 Gene3D G3DSA:3.30.70.1070 138 216 2.9E-13 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS23510 6f45c2901a67422984252b26c0d8a19b 220 Pfam PF05036 Sporulation related domain 141 214 4.5E-11 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS23510 6f45c2901a67422984252b26c0d8a19b 220 SUPERFAMILY SSF110997 140 217 1.96E-12 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS24950 2483c3e3daedd412a63a9eb5efdc5d3a 464 Pfam PF13727 CoA-binding domain 65 238 6.5E-39 T 10-03-2017 RG49_RS24950 2483c3e3daedd412a63a9eb5efdc5d3a 464 Pfam PF02397 Bacterial sugar transferase 274 456 2.0E-58 T 10-03-2017 IPR003362 Bacterial sugar transferase RG49_RS24950 2483c3e3daedd412a63a9eb5efdc5d3a 464 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 24 464 3.5E-150 T 10-03-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase RG49_RS24950 2483c3e3daedd412a63a9eb5efdc5d3a 464 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 25 464 1.5E-164 T 10-03-2017 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 RG49_RS02805 a10f64c0ce0a7393749614aa72476598 160 SUPERFAMILY SSF49401 27 160 3.63E-19 T 10-03-2017 IPR008966 Adhesion domain RG49_RS02805 a10f64c0ce0a7393749614aa72476598 160 Gene3D G3DSA:2.60.40.1090 27 157 3.7E-16 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 SUPERFAMILY SSF53474 9 253 1.28E-51 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 Pfam PF00561 alpha/beta hydrolase fold 14 115 9.0E-17 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 Gene3D G3DSA:3.40.50.1820 11 253 6.6E-49 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 TIGRFAM TIGR03611 RutD: pyrimidine utilization protein D 1 257 4.8E-124 T 10-03-2017 IPR019913 Pyrimidine utilisation protein RutD GO:0006212|GO:0016811 RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 9.9E-5 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 9.9E-5 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 9.9E-5 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 9.9E-5 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS05650 d0f8f1f81c23aed95b845fedae8f557c 266 Hamap MF_00832 Putative aminoacrylate hydrolase RutD [rutD]. 1 258 50.742 T 10-03-2017 IPR019913 Pyrimidine utilisation protein RutD GO:0006212|GO:0016811 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 SUPERFAMILY SSF51905 337 394 6.68E-59 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 SUPERFAMILY SSF51905 3 188 6.68E-59 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 Gene3D G3DSA:3.50.50.60 3 186 2.5E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 Gene3D G3DSA:3.50.50.60 339 394 2.5E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 362 369 7.6E-7 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 7.6E-7 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.6E-7 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 6.4E-5 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 369 6.4E-5 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.4E-5 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 392 1.6E-128 T 10-03-2017 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 Gene3D G3DSA:2.40.30.10 188 269 2.3E-29 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 Pfam PF03486 HI0933-like protein 5 392 3.8E-156 T 10-03-2017 RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 Gene3D G3DSA:1.10.8.260 270 322 3.5E-25 T 10-03-2017 IPR023166 HI0933 insert-like domain RG49_RS17100 1511eafe55a75e23917c892999a5770d 400 SUPERFAMILY SSF160996 190 338 2.75E-43 T 10-03-2017 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 24 188 7.1E-54 T 10-03-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 218 230 - T 10-03-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 SUPERFAMILY SSF48179 283 484 5.78E-68 T 10-03-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 Gene3D G3DSA:1.10.1040.10 283 485 1.4E-76 T 10-03-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 SUPERFAMILY SSF51735 10 281 1.46E-94 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 PRINTS PR00084 Mannitol dehydrogenase signature 179 192 1.9E-20 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 PRINTS PR00084 Mannitol dehydrogenase signature 25 35 1.9E-20 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 PRINTS PR00084 Mannitol dehydrogenase signature 248 263 1.9E-20 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 PRINTS PR00084 Mannitol dehydrogenase signature 218 231 1.9E-20 T 10-03-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 Gene3D G3DSA:3.40.50.720 10 281 6.3E-112 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12390 041aa6ded95d04a99f506a5515b1c989 486 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 216 463 2.2E-101 T 10-03-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 RG49_RS04730 e3552b4ea6d8fd8fd8efafa5032cb82a 513 TIGRFAM TIGR00774 NhaB: Na+/H+ antiporter NhaB 1 512 0.0 T 10-03-2017 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 RG49_RS04730 e3552b4ea6d8fd8fd8efafa5032cb82a 513 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 513 368.351 T 10-03-2017 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 RG49_RS04730 e3552b4ea6d8fd8fd8efafa5032cb82a 513 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 511 0.0 T 10-03-2017 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 RG49_RS08490 6b148cce633e9f46d694cfdaf9a184f1 349 SUPERFAMILY SSF89733 1 334 2.49E-108 T 10-03-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS08490 6b148cce633e9f46d694cfdaf9a184f1 349 Gene3D G3DSA:1.10.1530.10 1 71 1.2E-27 T 10-03-2017 RG49_RS08490 6b148cce633e9f46d694cfdaf9a184f1 349 TIGRFAM TIGR03175 AllD: ureidoglycolate dehydrogenase 1 349 1.4E-197 T 10-03-2017 IPR017590 Ureidoglycolate dehydrogenase KEGG: 00062+1.1.1.35|KEGG: 00071+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00230+1.1.1.350|KEGG: 00280+1.1.1.35|KEGG: 00281+1.1.1.35|KEGG: 00310+1.1.1.35|KEGG: 00362+1.1.1.35|KEGG: 00380+1.1.1.35|KEGG: 00623+1.1.1.35|KEGG: 00650+1.1.1.35|KEGG: 00720+1.1.1.35|KEGG: 00930+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5136|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401 RG49_RS08490 6b148cce633e9f46d694cfdaf9a184f1 349 Pfam PF02615 Malate/L-lactate dehydrogenase 3 331 2.2E-110 T 10-03-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS08490 6b148cce633e9f46d694cfdaf9a184f1 349 Gene3D G3DSA:3.30.1370.60 72 271 3.9E-76 T 10-03-2017 RG49_RS06140 ff89b03529c68fcffe6ae73cf112382f 297 SUPERFAMILY SSF56112 4 270 5.61E-27 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS06140 ff89b03529c68fcffe6ae73cf112382f 297 Gene3D G3DSA:3.90.1200.10 94 255 5.2E-8 T 10-03-2017 RG49_RS06140 ff89b03529c68fcffe6ae73cf112382f 297 Pfam PF01636 Phosphotransferase enzyme family 64 238 3.3E-6 T 10-03-2017 IPR002575 Aminoglycoside phosphotransferase RG49_RS20670 f1e10b75bbd9b40c3c1bed33c1a8dddd 172 Pfam PF09480 Type III secretion system protein PrgH-EprH (PrgH) 18 165 4.6E-19 T 10-03-2017 IPR019029 Type III secretion system, PrgH/EprH-like GO:0016021 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 Pfam PF13411 MerR HTH family regulatory protein 1 66 6.0E-18 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 SMART SM00422 1 70 4.4E-30 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 SUPERFAMILY SSF46955 1 126 1.21E-35 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 Gene3D G3DSA:1.10.1660.10 56 131 2.3E-25 T 10-03-2017 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 1.4E-62 T 10-03-2017 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 Gene3D G3DSA:1.10.1660.10 1 55 3.1E-23 T 10-03-2017 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.6E-7 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.6E-7 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS08635 d5ede7fa852bcbb40f345a0f77c2fb31 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 6.6E-7 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS17860 d846b3446c74769630da84764ee91886 196 SUPERFAMILY SSF54534 2 140 2.75E-33 T 10-03-2017 RG49_RS17860 d846b3446c74769630da84764ee91886 196 Gene3D G3DSA:3.10.50.40 2 80 5.2E-16 T 10-03-2017 RG49_RS17860 d846b3446c74769630da84764ee91886 196 Gene3D G3DSA:3.10.50.40 126 141 5.2E-16 T 10-03-2017 RG49_RS17860 d846b3446c74769630da84764ee91886 196 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 5 136 1.6E-9 T 10-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 RG49_RS00385 f280d9f948d7fad2e551a8eb6e58ff3f 165 Pfam PF00210 Ferritin-like domain 7 143 3.0E-35 T 10-03-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 RG49_RS00385 f280d9f948d7fad2e551a8eb6e58ff3f 165 Gene3D G3DSA:1.20.1260.10 1 160 2.9E-58 T 10-03-2017 IPR012347 Ferritin-related RG49_RS00385 f280d9f948d7fad2e551a8eb6e58ff3f 165 SUPERFAMILY SSF47240 3 161 3.54E-56 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS08995 409893d58a5d003d03cd88763bd4d100 454 SUPERFAMILY SSF103473 6 390 1.19E-61 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS08995 409893d58a5d003d03cd88763bd4d100 454 Pfam PF07690 Major Facilitator Superfamily 20 354 3.5E-39 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS08995 409893d58a5d003d03cd88763bd4d100 454 Gene3D G3DSA:1.20.1250.20 11 193 2.2E-34 T 10-03-2017 RG49_RS08995 409893d58a5d003d03cd88763bd4d100 454 Gene3D G3DSA:1.20.1250.20 212 392 1.8E-19 T 10-03-2017 RG49_RS17865 00bc8ba7a63c1b8b0b2f031a6c496b49 72 Gene3D G3DSA:1.20.5.300 2 52 2.3E-21 T 10-03-2017 RG49_RS17865 00bc8ba7a63c1b8b0b2f031a6c496b49 72 Hamap MF_00715 Protein SlyX [slyX]. 5 72 17.586 T 10-03-2017 IPR007236 SlyX RG49_RS17865 00bc8ba7a63c1b8b0b2f031a6c496b49 72 Pfam PF04102 SlyX 6 72 4.7E-24 T 10-03-2017 IPR007236 SlyX RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 Gene3D G3DSA:2.40.110.10 123 217 3.4E-23 T 10-03-2017 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 108 1.1E-14 T 10-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 Gene3D G3DSA:1.10.540.10 1 110 7.2E-19 T 10-03-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 SUPERFAMILY SSF47203 226 379 1.93E-45 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 215 1.9E-21 T 10-03-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 Hamap MF_01052 Crotonobetainyl-CoA dehydrogenase [caiA]. 1 380 91.978 T 10-03-2017 IPR023450 Crotonobetainyl-CoA dehydrogenase CaiA GO:0009437|GO:0016627|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 Gene3D G3DSA:1.20.140.10 218 380 3.9E-51 T 10-03-2017 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 376 5.0E-46 T 10-03-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 10-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 SUPERFAMILY SSF56645 1 227 3.27E-52 T 10-03-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 RG49_RS11670 fa68e48e0f4f5f7e3a1b394e6ac0e47f 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 10-03-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 RG49_RS07175 40f70f11ca160246f4c16cbbc902b8a6 427 SUPERFAMILY SSF51126 407 420 2.69E-36 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS07175 40f70f11ca160246f4c16cbbc902b8a6 427 SUPERFAMILY SSF51126 75 155 2.69E-36 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS07175 40f70f11ca160246f4c16cbbc902b8a6 427 SUPERFAMILY SSF51126 192 376 2.69E-36 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS07175 40f70f11ca160246f4c16cbbc902b8a6 427 ProSitePatterns PS00503 Pectinesterase signature 2. 280 289 - T 10-03-2017 IPR033131 Pectinesterase, Asp active site KEGG: 00040+3.1.1.11|KEGG: 00500+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 RG49_RS07175 40f70f11ca160246f4c16cbbc902b8a6 427 Gene3D G3DSA:2.160.20.10 77 423 1.1E-67 T 10-03-2017 IPR012334 Pectin lyase fold RG49_RS07175 40f70f11ca160246f4c16cbbc902b8a6 427 Pfam PF01095 Pectinesterase 194 318 9.5E-11 T 10-03-2017 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|KEGG: 00500+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 RG49_RS15915 e0f9e13214247c73bd510c739450d909 439 PIRSF PIRSF002808 6 439 6.9E-158 T 10-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS15915 e0f9e13214247c73bd510c739450d909 439 ProSitePatterns PS00942 glpT family of transporters signature. 151 167 - T 10-03-2017 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-3229133|Reactome: R-HSA-70153 RG49_RS15915 e0f9e13214247c73bd510c739450d909 439 Pfam PF07690 Major Facilitator Superfamily 35 396 2.8E-49 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS15915 e0f9e13214247c73bd510c739450d909 439 SUPERFAMILY SSF103473 17 432 5.75E-77 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS15915 e0f9e13214247c73bd510c739450d909 439 Gene3D G3DSA:1.20.1250.20 240 434 7.3E-38 T 10-03-2017 RG49_RS15915 e0f9e13214247c73bd510c739450d909 439 Gene3D G3DSA:1.20.1250.20 23 210 4.1E-48 T 10-03-2017 RG49_RS15915 e0f9e13214247c73bd510c739450d909 439 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 413 1.4E-153 T 10-03-2017 RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 6.6E-19 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 SUPERFAMILY SSF46785 8 112 8.08E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 SUPERFAMILY SSF53850 99 298 1.03E-29 T 10-03-2017 RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 Pfam PF03466 LysR substrate binding domain 98 296 1.7E-31 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 Gene3D G3DSA:1.10.10.10 8 93 1.7E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 9.9E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 9.9E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 9.9E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 Gene3D G3DSA:3.40.190.10 99 197 3.9E-20 T 10-03-2017 RG49_RS19120 1a6ccd40122dc3fb213c88d147319706 312 Gene3D G3DSA:3.40.190.10 198 267 1.7E-7 T 10-03-2017 RG49_RS11325 6ad437c6258227e99ba583609f236310 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 1.8E-9 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS11325 6ad437c6258227e99ba583609f236310 146 Gene3D G3DSA:3.30.700.10 7 135 9.2E-33 T 10-03-2017 RG49_RS11325 6ad437c6258227e99ba583609f236310 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS11325 6ad437c6258227e99ba583609f236310 146 SUPERFAMILY SSF54523 7 113 1.05E-22 T 10-03-2017 RG49_RS11325 6ad437c6258227e99ba583609f236310 146 Pfam PF13633 Prokaryotic N-terminal methylation site 4 30 5.0E-11 T 10-03-2017 IPR012902 Prokaryotic N-terminal methylation site RG49_RS00430 dd335e09d83a4d7d9b633db2dfc70b41 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 316 1.2E-45 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 18 652 47.309 T 10-03-2017 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 KEGG: 00650+2.3.1.19 RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Gene3D G3DSA:3.40.630.30 381 413 1.4E-10 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Gene3D G3DSA:3.40.630.30 447 513 1.4E-10 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Gene3D G3DSA:3.40.50.300 169 281 3.1E-4 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 SUPERFAMILY SSF52540 168 285 7.25E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Pfam PF13718 GNAT acetyltransferase 2 369 483 1.6E-16 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Pfam PF05127 Helicase 197 337 1.8E-41 T 10-03-2017 IPR007807 Helicase domain Reactome: R-HSA-6790901 RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Pfam PF17176 tRNA-binding domain 537 653 1.4E-37 T 10-03-2017 IPR033442 tRNA(Met) cytidine acetyltransferase TmcA, tRNA-binding domain KEGG: 00650+2.3.1.19 RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 Pfam PF08351 Domain of unknown function (DUF1726) 66 147 1.9E-6 T 10-03-2017 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 SUPERFAMILY SSF55729 364 418 2.24E-11 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS22790 3bd54cd62bd977d1439fce991e1a7036 671 SUPERFAMILY SSF55729 454 513 2.24E-11 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS02655 a443995e9b3817c05c20462d0fffcfa1 330 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 305 4.5E-47 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS23550 e17e32ecc758294b9a222b3b100f74de 257 SUPERFAMILY SSF52540 6 251 3.59E-75 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23550 e17e32ecc758294b9a222b3b100f74de 257 SMART SM00382 30 229 7.6E-16 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS23550 e17e32ecc758294b9a222b3b100f74de 257 PIRSF PIRSF039085 2 257 3.4E-122 T 10-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 RG49_RS23550 e17e32ecc758294b9a222b3b100f74de 257 Gene3D G3DSA:3.40.50.300 6 252 2.4E-81 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23550 e17e32ecc758294b9a222b3b100f74de 257 Pfam PF00005 ABC transporter 21 181 1.3E-33 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS23550 e17e32ecc758294b9a222b3b100f74de 257 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS01225 641300ae470669096f53e556a4003f65 182 SUPERFAMILY SSF69118 3 173 3.04E-37 T 10-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 RG49_RS01225 641300ae470669096f53e556a4003f65 182 Pfam PF02627 Carboxymuconolactone decarboxylase family 52 122 1.4E-7 T 10-03-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 RG49_RS01225 641300ae470669096f53e556a4003f65 182 Gene3D G3DSA:1.20.1290.10 30 175 2.0E-38 T 10-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 RG49_RS09140 bfa938dc46c7581c7a64934a5d5593eb 400 SUPERFAMILY SSF56300 1 335 2.64E-61 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS09140 bfa938dc46c7581c7a64934a5d5593eb 400 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 254 8.1E-96 T 10-03-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 RG49_RS09140 bfa938dc46c7581c7a64934a5d5593eb 400 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 373 1.8E-24 T 10-03-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain RG49_RS09140 bfa938dc46c7581c7a64934a5d5593eb 400 Pfam PF00149 Calcineurin-like phosphoesterase 1 225 9.2E-19 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS09140 bfa938dc46c7581c7a64934a5d5593eb 400 Gene3D G3DSA:3.60.21.10 1 275 5.2E-67 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS15500 865718f6bc715a9dacbba0897f85b5d6 147 Gene3D G3DSA:3.40.50.360 1 146 4.8E-34 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS15500 865718f6bc715a9dacbba0897f85b5d6 147 SUPERFAMILY SSF52218 1 146 8.19E-39 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS15500 865718f6bc715a9dacbba0897f85b5d6 147 Pfam PF00258 Flavodoxin 7 138 7.9E-24 T 10-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 Pfam PF03882 MukF winged-helix domain 3 117 8.1E-58 T 10-03-2017 IPR033439 Chromosome partition protein MukF, winged-helix domain RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 Pfam PF17192 MukF middle domain 121 281 4.4E-85 T 10-03-2017 IPR033440 Chromosome partition protein MukF, middle domain RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 PIRSF PIRSF018282 1 440 1.0E-244 T 10-03-2017 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 SUPERFAMILY SSF140570 119 281 1.23E-77 T 10-03-2017 IPR033440 Chromosome partition protein MukF, middle domain RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 Pfam PF17193 MukF C-terminal domain 283 440 4.5E-81 T 10-03-2017 IPR033441 Chromosome partition protein MukF, C-terminal domain RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 Gene3D G3DSA:1.10.10.10 24 118 4.7E-49 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 SUPERFAMILY SSF46785 8 118 1.83E-48 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06125 acbb48e71c3c393506fdb692a2b1f8f3 440 Hamap MF_01803 Chromosome partition protein MukF [mukF]. 1 440 57.932 T 10-03-2017 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 RG49_RS24130 e7e732f195c2b45b50d9be60c9a66db8 200 SUPERFAMILY SSF48695 17 196 1.09E-64 T 10-03-2017 IPR011031 Multihaem cytochrome RG49_RS24130 e7e732f195c2b45b50d9be60c9a66db8 200 PIRSF PIRSF000013 1 200 4.7E-108 T 10-03-2017 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 RG49_RS24130 e7e732f195c2b45b50d9be60c9a66db8 200 TIGRFAM TIGR02161 napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family 11 194 5.7E-106 T 10-03-2017 IPR011885 Periplasmic nitrate reductase c-type cytochrome, NapC/NirT GO:0016021|GO:0019333|GO:0020037 RG49_RS24130 e7e732f195c2b45b50d9be60c9a66db8 200 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 22 193 2.0E-77 T 10-03-2017 IPR005126 NapC/NirT cytochrome c, N-terminal RG49_RS24130 e7e732f195c2b45b50d9be60c9a66db8 200 Gene3D G3DSA:1.10.3820.10 21 193 5.2E-28 T 10-03-2017 RG49_RS19590 0d4c39db9daab88884da9237530e7514 275 Gene3D G3DSA:3.60.21.10 14 258 7.4E-42 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS19590 0d4c39db9daab88884da9237530e7514 275 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 15 261 43.006 T 10-03-2017 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 RG49_RS19590 0d4c39db9daab88884da9237530e7514 275 Pfam PF00149 Calcineurin-like phosphoesterase 16 206 4.6E-20 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS19590 0d4c39db9daab88884da9237530e7514 275 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 206 261 9.0E-27 T 10-03-2017 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 RG49_RS19590 0d4c39db9daab88884da9237530e7514 275 SUPERFAMILY SSF56300 16 269 1.27E-61 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS08860 db48d4e8f270845af318b767af7d6024 286 Gene3D G3DSA:3.10.129.10 125 284 4.3E-56 T 10-03-2017 IPR029069 HotDog domain RG49_RS08860 db48d4e8f270845af318b767af7d6024 286 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 283 2.4E-105 T 10-03-2017 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-75105 RG49_RS08860 db48d4e8f270845af318b767af7d6024 286 SUPERFAMILY SSF54637 5 114 2.95E-42 T 10-03-2017 IPR029069 HotDog domain RG49_RS08860 db48d4e8f270845af318b767af7d6024 286 Pfam PF13622 Thioesterase-like superfamily 32 282 6.0E-58 T 10-03-2017 RG49_RS08860 db48d4e8f270845af318b767af7d6024 286 SUPERFAMILY SSF54637 116 284 1.22E-58 T 10-03-2017 IPR029069 HotDog domain RG49_RS08860 db48d4e8f270845af318b767af7d6024 286 Gene3D G3DSA:3.10.129.10 5 116 6.2E-50 T 10-03-2017 IPR029069 HotDog domain RG49_RS24270 0fb8af4a1257bc7907737a8b84a58318 518 Pfam PF12792 CSS motif domain associated with EAL 42 239 1.5E-42 T 10-03-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain RG49_RS24270 0fb8af4a1257bc7907737a8b84a58318 518 Gene3D G3DSA:3.20.20.450 267 512 3.2E-76 T 10-03-2017 IPR001633 EAL domain RG49_RS24270 0fb8af4a1257bc7907737a8b84a58318 518 SMART SM00052 260 505 4.7E-106 T 10-03-2017 IPR001633 EAL domain RG49_RS24270 0fb8af4a1257bc7907737a8b84a58318 518 Pfam PF00563 EAL domain 267 500 9.1E-67 T 10-03-2017 IPR001633 EAL domain RG49_RS24270 0fb8af4a1257bc7907737a8b84a58318 518 SUPERFAMILY SSF141868 267 514 8.11E-73 T 10-03-2017 IPR001633 EAL domain RG49_RS14400 6f01c581f6ee902a2694e4d2a8c90988 205 PIRSF PIRSF011444 1 205 1.5E-97 T 10-03-2017 IPR009706 Protein of unknown function DUF1287 RG49_RS14400 6f01c581f6ee902a2694e4d2a8c90988 205 ProDom PD357862 YIJF PERIPLASMIC ECS4873 PRECURSOR CC1379 SIGNAL DOMAIN PM0035 31 202 2.0E-99 T 10-03-2017 IPR009706 Protein of unknown function DUF1287 RG49_RS14400 6f01c581f6ee902a2694e4d2a8c90988 205 Pfam PF06940 Domain of unknown function (DUF1287) 41 202 4.8E-71 T 10-03-2017 IPR009706 Protein of unknown function DUF1287 RG49_RS10925 00a782218a942c1a99d326d5dc7f41eb 161 Gene3D G3DSA:3.30.910.20 92 161 2.1E-35 T 10-03-2017 RG49_RS10925 00a782218a942c1a99d326d5dc7f41eb 161 Gene3D G3DSA:3.30.910.20 11 57 2.1E-35 T 10-03-2017 RG49_RS10925 00a782218a942c1a99d326d5dc7f41eb 161 Pfam PF03938 Outer membrane protein (OmpH-like) 9 159 1.5E-29 T 10-03-2017 IPR005632 Chaperone protein Skp GO:0051082 RG49_RS10925 00a782218a942c1a99d326d5dc7f41eb 161 SMART SM00935 10 161 2.4E-39 T 10-03-2017 IPR005632 Chaperone protein Skp GO:0051082 RG49_RS10925 00a782218a942c1a99d326d5dc7f41eb 161 SUPERFAMILY SSF111384 20 160 6.41E-32 T 10-03-2017 IPR024930 Skp domain RG49_RS10925 00a782218a942c1a99d326d5dc7f41eb 161 PIRSF PIRSF002094 1 161 1.0E-51 T 10-03-2017 IPR005632 Chaperone protein Skp GO:0051082 RG49_RS06505 6ce61e826b17c7c70a5e13980790f51c 158 Pfam PF10722 Putative bacterial sensory transduction regulator 9 131 1.1E-16 T 10-03-2017 IPR019660 Putative sensory transduction regulator YbjN RG49_RS00305 5915fd294adc50bead12c662ce0d2e54 328 Gene3D G3DSA:3.40.50.1100 112 325 2.4E-68 T 10-03-2017 RG49_RS00305 5915fd294adc50bead12c662ce0d2e54 328 PIRSF PIRSF006278 2 328 2.4E-93 T 10-03-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase RG49_RS00305 5915fd294adc50bead12c662ce0d2e54 328 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 12 328 2.7E-146 T 10-03-2017 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 RG49_RS00305 5915fd294adc50bead12c662ce0d2e54 328 Hamap MF_01045 D-cysteine desulfhydrase [dcyD]. 1 328 80.774 T 10-03-2017 IPR023702 D-cysteine desulphhydrase, bacterial GO:0019148 KEGG: 00270+4.4.1.15 RG49_RS00305 5915fd294adc50bead12c662ce0d2e54 328 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 316 9.3E-55 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS00305 5915fd294adc50bead12c662ce0d2e54 328 SUPERFAMILY SSF53686 7 326 2.23E-86 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS01775 9e5e4071a9d1b9e3765784083543f591 115 PIRSF PIRSF005894 1 108 1.0E-52 T 10-03-2017 IPR014434 Monothiol glutaredoxin RG49_RS01775 9e5e4071a9d1b9e3765784083543f591 115 Pfam PF00462 Glutaredoxin 17 81 1.7E-18 T 10-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 RG49_RS01775 9e5e4071a9d1b9e3765784083543f591 115 Gene3D G3DSA:3.40.30.10 8 102 2.8E-32 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS01775 9e5e4071a9d1b9e3765784083543f591 115 SUPERFAMILY SSF52833 2 104 1.99E-35 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS01775 9e5e4071a9d1b9e3765784083543f591 115 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 101 4.7E-47 T 10-03-2017 IPR004480 Monothiol glutaredoxin-related RG49_RS03075 3a45d2275c220c4572dae520f5735b2c 248 Pfam PF01609 Transposase DDE domain 102 232 4.5E-16 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS03075 3a45d2275c220c4572dae520f5735b2c 248 Pfam PF13808 DDE_Tnp_1-associated 8 94 1.9E-30 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS10025 b8cbf2a585ac6e0c54ad2c33ffe7e79a 295 Pfam PF10938 YfdX protein 64 201 1.8E-36 T 10-03-2017 IPR021236 Uncharacterised protein family YfdX RG49_RS14355 fe5507fb382a0fab75c7421b41d25e0e 113 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 94 1.5E-12 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS14355 fe5507fb382a0fab75c7421b41d25e0e 113 SUPERFAMILY SSF52794 4 98 1.36E-26 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS14355 fe5507fb382a0fab75c7421b41d25e0e 113 Gene3D G3DSA:3.40.50.2300 3 99 7.6E-31 T 10-03-2017 RG49_RS14355 fe5507fb382a0fab75c7421b41d25e0e 113 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 85 5.7E-25 T 10-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 RG49_RS10585 0814ff7b3cdfca46282b3b5e300c43af 256 Pfam PF00795 Carbon-nitrogen hydrolase 6 241 1.3E-31 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS10585 0814ff7b3cdfca46282b3b5e300c43af 256 SUPERFAMILY SSF56317 4 249 1.19E-60 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS10585 0814ff7b3cdfca46282b3b5e300c43af 256 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 137 157 - T 10-03-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site RG49_RS10585 0814ff7b3cdfca46282b3b5e300c43af 256 Gene3D G3DSA:3.60.110.10 4 251 3.2E-59 T 10-03-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 RG49_RS18470 7e83a2f8447b1a959eb026f7a47d4917 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 6.8E-48 T 10-03-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 RG49_RS18470 7e83a2f8447b1a959eb026f7a47d4917 130 Gene3D G3DSA:3.30.230.10 4 130 3.5E-51 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS18470 7e83a2f8447b1a959eb026f7a47d4917 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.138 T 10-03-2017 IPR023035 Ribosomal protein S9, bacterial/plastid RG49_RS18470 7e83a2f8447b1a959eb026f7a47d4917 130 SUPERFAMILY SSF54211 5 130 1.59E-49 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS18470 7e83a2f8447b1a959eb026f7a47d4917 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 10-03-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 RG49_RS08700 9b82d4781f21605010344b7832934572 406 Pfam PF07690 Major Facilitator Superfamily 31 264 9.5E-25 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS08700 9b82d4781f21605010344b7832934572 406 Gene3D G3DSA:1.20.1250.20 27 204 7.2E-21 T 10-03-2017 RG49_RS08700 9b82d4781f21605010344b7832934572 406 Gene3D G3DSA:1.20.1250.20 222 401 4.0E-21 T 10-03-2017 RG49_RS08700 9b82d4781f21605010344b7832934572 406 SUPERFAMILY SSF103473 19 401 2.22E-56 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS19375 89743da0e8d34386567f46ec472079d8 254 Pfam PF08021 Siderophore-interacting FAD-binding domain 22 132 1.5E-34 T 10-03-2017 IPR013113 FAD-binding 9, siderophore-interacting RG49_RS19375 89743da0e8d34386567f46ec472079d8 254 Gene3D G3DSA:2.40.30.10 11 131 3.3E-34 T 10-03-2017 RG49_RS19375 89743da0e8d34386567f46ec472079d8 254 SUPERFAMILY SSF63380 2 137 1.68E-16 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS19375 89743da0e8d34386567f46ec472079d8 254 Pfam PF04954 Siderophore-interacting protein 142 253 6.9E-21 T 10-03-2017 IPR007037 Siderophore-interacting protein RG49_RS19375 89743da0e8d34386567f46ec472079d8 254 Gene3D G3DSA:3.40.50.80 135 252 5.4E-21 T 10-03-2017 RG49_RS21070 b149efe21b9aa1e715c4f7a2b8051d58 454 Gene3D G3DSA:3.30.1850.10 2 113 7.5E-54 T 10-03-2017 IPR027820 Domain of unknown function DUF4478 RG49_RS21070 b149efe21b9aa1e715c4f7a2b8051d58 454 Gene3D G3DSA:3.40.50.450 125 452 2.1E-124 T 10-03-2017 RG49_RS21070 b149efe21b9aa1e715c4f7a2b8051d58 454 Pfam PF03641 Possible lysine decarboxylase 190 329 1.5E-33 T 10-03-2017 IPR031100 LOG family RG49_RS21070 b149efe21b9aa1e715c4f7a2b8051d58 454 Pfam PF11892 Domain of unknown function (DUF3412) 333 452 2.3E-55 T 10-03-2017 IPR021826 Protein of unknown function DUF3412 RG49_RS21070 b149efe21b9aa1e715c4f7a2b8051d58 454 Pfam PF14793 Domain of unknown function (DUF4478) 4 109 4.5E-46 T 10-03-2017 IPR027820 Domain of unknown function DUF4478 RG49_RS21070 b149efe21b9aa1e715c4f7a2b8051d58 454 SUPERFAMILY SSF102405 118 330 6.56E-42 T 10-03-2017 RG49_RS17830 4e07c56169587996d0a84a2c24141d5d 340 Pfam PF00561 alpha/beta hydrolase fold 73 312 9.0E-31 T 10-03-2017 IPR000073 Alpha/beta hydrolase fold-1 RG49_RS17830 4e07c56169587996d0a84a2c24141d5d 340 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 239 280 - T 10-03-2017 IPR000952 AB hydrolase 4, conserved site RG49_RS17830 4e07c56169587996d0a84a2c24141d5d 340 Gene3D G3DSA:3.40.50.1820 260 336 2.4E-28 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS17830 4e07c56169587996d0a84a2c24141d5d 340 Gene3D G3DSA:3.40.50.1820 55 184 2.4E-28 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS17830 4e07c56169587996d0a84a2c24141d5d 340 SUPERFAMILY SSF53474 40 312 7.42E-38 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS17830 4e07c56169587996d0a84a2c24141d5d 340 PIRSF PIRSF005211 4 340 1.1E-111 T 10-03-2017 IPR012020 AB hydrolase 4 family RG49_RS15250 5e48f84aa5ae7f1793eb12dc593c0fcd 416 Pfam PF01943 Polysaccharide biosynthesis protein 4 283 1.1E-8 T 10-03-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 RG49_RS15250 5e48f84aa5ae7f1793eb12dc593c0fcd 416 Hamap MF_02024 Lipid III flippase [wzxE]. 1 416 39.967 T 10-03-2017 IPR032896 Lipid III flippase WzxE GO:0005886|GO:0009246 RG49_RS24580 60323bb6b500e1637fdeb6e88a462cbb 378 Gene3D G3DSA:3.40.50.410 214 334 2.5E-6 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS24580 60323bb6b500e1637fdeb6e88a462cbb 378 SMART SM00327 214 373 3.2E-11 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS24580 60323bb6b500e1637fdeb6e88a462cbb 378 Pfam PF05762 VWA domain containing CoxE-like protein 151 372 1.8E-67 T 10-03-2017 IPR008912 Uncharacterised protein family CoxE-like RG49_RS24580 60323bb6b500e1637fdeb6e88a462cbb 378 SUPERFAMILY SSF53300 212 356 1.05E-20 T 10-03-2017 IPR002035 von Willebrand factor, type A RG49_RS14885 45d812d75dacdd83dcfb27a79c2ea011 476 Pfam PF06097 Bacterial protein of unknown function (DUF945) 4 464 3.0E-95 T 10-03-2017 IPR010352 Protein of unknown function DUF945 RG49_RS11660 519318b39f87a1b89045902a8e149408 256 SMART SM00893 22 215 1.3E-41 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS11660 519318b39f87a1b89045902a8e149408 256 Hamap MF_01055 Protein FixA [fixA]. 1 256 53.874 T 10-03-2017 IPR023463 Electron transfer flavoprotein, FixA subunit GO:0009055|GO:0009437 RG49_RS11660 519318b39f87a1b89045902a8e149408 256 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 159 179 - T 10-03-2017 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 RG49_RS11660 519318b39f87a1b89045902a8e149408 256 Pfam PF01012 Electron transfer flavoprotein domain 28 210 6.1E-39 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS11660 519318b39f87a1b89045902a8e149408 256 Gene3D G3DSA:3.40.50.620 1 254 1.9E-70 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11660 519318b39f87a1b89045902a8e149408 256 SUPERFAMILY SSF52402 1 253 1.26E-60 T 10-03-2017 RG49_RS11660 519318b39f87a1b89045902a8e149408 256 PIRSF PIRSF000090 1 256 1.9E-68 T 10-03-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 RG49_RS20220 69bb77a7a3d14d6a6f90fb3064cadc4e 147 Gene3D G3DSA:3.40.930.10 1 146 5.2E-50 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS20220 69bb77a7a3d14d6a6f90fb3064cadc4e 147 SUPERFAMILY SSF55804 1 145 1.96E-33 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS20220 69bb77a7a3d14d6a6f90fb3064cadc4e 147 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS20220 69bb77a7a3d14d6a6f90fb3064cadc4e 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 145 8.9E-28 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 Gene3D G3DSA:3.40.50.2300 172 338 1.3E-35 T 10-03-2017 RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 SMART SM00354 4 72 0.0031 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 47 1.3E-8 T 10-03-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 SUPERFAMILY SSF53822 72 338 2.03E-39 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 Gene3D G3DSA:3.40.50.2300 75 171 4.9E-11 T 10-03-2017 RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 SUPERFAMILY SSF47413 4 57 9.93E-9 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 Pfam PF13377 Periplasmic binding protein-like domain 174 337 2.0E-26 T 10-03-2017 RG49_RS16085 6009c3994c248df3b1c151acc8d0bc6a 356 Gene3D G3DSA:1.10.260.40 3 47 5.1E-12 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS20920 02098506ab4286f96e5b4e409908f308 135 Pfam PF10713 Protein of unknown function (DUF2509) 15 132 1.1E-33 T 10-03-2017 IPR019652 Protein of unknown function DUF2509 RG49_RS20985 32cd920929ed503e35d0911bc3b6f973 268 Gene3D G3DSA:3.40.50.720 5 262 9.7E-54 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS20985 32cd920929ed503e35d0911bc3b6f973 268 SUPERFAMILY SSF69572 10 259 6.41E-63 T 10-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 RG49_RS20985 32cd920929ed503e35d0911bc3b6f973 268 Pfam PF00899 ThiF family 20 260 5.0E-37 T 10-03-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 RG49_RS04780 cc45c1a3a8952b8417341d5084001975 122 Pfam PF05666 Fels-1 Prophage Protein-like 22 61 1.2E-15 T 10-03-2017 IPR008617 Uncharacterised protein family, YcgJ RG49_RS04780 cc45c1a3a8952b8417341d5084001975 122 Pfam PF05666 Fels-1 Prophage Protein-like 69 120 4.3E-19 T 10-03-2017 IPR008617 Uncharacterised protein family, YcgJ RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 SUPERFAMILY SSF54292 218 321 2.36E-23 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 SUPERFAMILY SSF63380 3 104 7.88E-26 T 10-03-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 SUPERFAMILY SSF52343 106 223 5.11E-27 T 10-03-2017 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 Gene3D G3DSA:2.40.30.10 5 104 2.2E-31 T 10-03-2017 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 Pfam PF00175 Oxidoreductase NAD-binding domain 117 207 1.6E-7 T 10-03-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 242 312 5.9E-12 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 135 2.9E-32 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 2.9E-32 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 80 94 2.9E-32 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 150 2.9E-32 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 2.9E-32 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 94 108 2.9E-32 T 10-03-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 270 278 - T 10-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 Gene3D G3DSA:3.10.20.30 222 319 6.6E-24 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 Gene3D G3DSA:3.40.50.80 110 221 4.0E-29 T 10-03-2017 RG49_RS00960 c6f8b0700a8ba6325f9270e05567230e 321 Pfam PF00970 Oxidoreductase FAD-binding domain 9 103 4.5E-6 T 10-03-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 RG49_RS05685 759960125ed038109fffe0e8f45fb52c 198 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 198 40.837 T 10-03-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 RG49_RS05685 759960125ed038109fffe0e8f45fb52c 198 Gene3D G3DSA:3.40.50.360 1 197 9.8E-73 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS05685 759960125ed038109fffe0e8f45fb52c 198 SUPERFAMILY SSF52218 1 197 5.24E-62 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS05685 759960125ed038109fffe0e8f45fb52c 198 Pfam PF03358 NADPH-dependent FMN reductase 13 143 6.8E-14 T 10-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 RG49_RS05685 759960125ed038109fffe0e8f45fb52c 198 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 196 2.3E-104 T 10-03-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 RG49_RS12430 6f683cbaeccd923e7050825e343c7704 212 Gene3D G3DSA:2.60.40.1090 63 212 3.5E-38 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12430 6f683cbaeccd923e7050825e343c7704 212 Pfam PF00419 Fimbrial protein 66 212 4.9E-21 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12430 6f683cbaeccd923e7050825e343c7704 212 SUPERFAMILY SSF49401 64 212 1.54E-34 T 10-03-2017 IPR008966 Adhesion domain RG49_RS21610 fc4f077eb268a92f29017fcaaedd8fa3 61 Pfam PF02599 Global regulator protein family 1 52 2.6E-27 T 10-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 RG49_RS21610 fc4f077eb268a92f29017fcaaedd8fa3 61 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-20 T 10-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 RG49_RS21610 fc4f077eb268a92f29017fcaaedd8fa3 61 Hamap MF_00167 Carbon storage regulator [csrA]. 1 61 20.514 T 10-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 RG49_RS21610 fc4f077eb268a92f29017fcaaedd8fa3 61 SUPERFAMILY SSF117130 1 54 3.66E-21 T 10-03-2017 RG49_RS21610 fc4f077eb268a92f29017fcaaedd8fa3 61 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 57 2.0E-31 T 10-03-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 1.4E-18 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 1.4E-18 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.4E-18 T 10-03-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 Gene3D G3DSA:2.60.410.10 285 376 1.4E-30 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 Gene3D G3DSA:3.40.710.10 27 283 1.7E-98 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 285 376 8.5E-24 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 SUPERFAMILY SSF56601 14 285 7.11E-83 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 SUPERFAMILY SSF69189 285 378 3.73E-25 T 10-03-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 30 266 3.5E-102 T 10-03-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 RG49_RS06810 067b145a4e68e748e7ae38bdd7fa3de2 400 SMART SM00936 285 376 4.4E-35 T 10-03-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 RG49_RS07110 4af7f177bfbdcea92812e6292c56fae6 81 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 81 3.3E-24 T 10-03-2017 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 RG49_RS07110 4af7f177bfbdcea92812e6292c56fae6 81 SUPERFAMILY SSF54285 1 81 6.54E-24 T 10-03-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp RG49_RS07110 4af7f177bfbdcea92812e6292c56fae6 81 Pfam PF02597 ThiS family 4 81 6.7E-22 T 10-03-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 RG49_RS07110 4af7f177bfbdcea92812e6292c56fae6 81 Gene3D G3DSA:3.10.20.30 1 81 3.3E-26 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS24430 7456c9822d0da0da2bb0da9cdbe5e842 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 325 6.3E-49 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS03725 f55f791164e78b9245b89298c75834ae 162 Pfam PF14163 Super-infection exclusion protein B 21 159 4.6E-29 T 10-03-2017 IPR025982 Superinfection exclusion protein B RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 Pfam PF03473 MOSC domain 139 262 8.9E-31 T 10-03-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 296 362 7.1E-14 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 323 331 - T 10-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 Pfam PF03476 MOSC N-terminal beta barrel domain 2 116 1.4E-29 T 10-03-2017 IPR005303 MOSC, N-terminal beta barrel RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 SUPERFAMILY SSF141673 6 132 9.15E-28 T 10-03-2017 RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 SUPERFAMILY SSF50800 147 264 1.83E-17 T 10-03-2017 IPR011037 Pyruvate kinase-like, insert domain RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 SUPERFAMILY SSF50800 3 50 1.83E-17 T 10-03-2017 IPR011037 Pyruvate kinase-like, insert domain RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 SUPERFAMILY SSF54292 284 367 6.82E-20 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS05985 9a92906b804ad49a2fa5bd89c6099101 369 Gene3D G3DSA:3.10.20.30 279 367 8.6E-22 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 PIRSF PIRSF000089 3 313 1.3E-85 T 10-03-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 SUPERFAMILY SSF52467 190 310 2.81E-41 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 Gene3D G3DSA:3.40.50.620 5 171 3.5E-24 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 SUPERFAMILY SSF52402 7 169 1.81E-22 T 10-03-2017 RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 Pfam PF01012 Electron transfer flavoprotein domain 42 169 7.3E-14 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 Hamap MF_01056 Protein FixB [fixB]. 1 313 59.459 T 10-03-2017 IPR023461 Electron transfer flavoprotein FixB subunit GO:0009437 RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 SMART SM00893 7 180 1.1E-12 T 10-03-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 Gene3D G3DSA:3.40.50.1220 185 311 1.0E-48 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 255 281 - T 10-03-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 RG49_RS11655 a6a7192af9aac1d6a8179ccd34c0e88f 313 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 274 9.1E-30 T 10-03-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 21 131 4.9E-50 T 10-03-2017 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 Pfam PF14489 QueF-like protein 196 270 2.5E-27 T 10-03-2017 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 282 169.824 T 10-03-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 PIRSF PIRSF004750 6 282 5.4E-132 T 10-03-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 TIGRFAM TIGR03138 QueF: queuine synthase 11 282 2.6E-131 T 10-03-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 SUPERFAMILY SSF55620 186 268 1.04E-10 T 10-03-2017 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 Gene3D G3DSA:3.30.1130.10 145 282 1.7E-56 T 10-03-2017 RG49_RS21075 5f25401f9308dc745b15722b4656958e 282 Gene3D G3DSA:3.30.1130.10 21 138 2.3E-45 T 10-03-2017 RG49_RS06555 28c5e069873d22195f078b4bfa1a85e1 1025 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 200 567 3.2E-94 T 10-03-2017 IPR010090 Phage tail tape measure protein RG49_RS06555 28c5e069873d22195f078b4bfa1a85e1 1025 Pfam PF10145 Phage-related minor tail protein 246 457 1.3E-22 T 10-03-2017 IPR010090 Phage tail tape measure protein RG49_RS00825 451eb0ab172f6de5db3b6d9d86ca8e51 47 Pfam PF13998 MgrB protein 19 47 2.2E-17 T 10-03-2017 IPR020907 PhoP/PhoQ regulator MgrB RG49_RS00825 451eb0ab172f6de5db3b6d9d86ca8e51 47 Hamap MF_01596 PhoP/PhoQ regulator MgrB [mgrB]. 1 47 21.855 T 10-03-2017 IPR020907 PhoP/PhoQ regulator MgrB RG49_RS22370 f28ad39557289061743829a0c5dd4184 106 SUPERFAMILY SSF50022 1 103 3.54E-29 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS22370 f28ad39557289061743829a0c5dd4184 106 Hamap MF_01650 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit [hcaC]. 1 106 45.087 T 10-03-2017 IPR023739 3-phenylpropionate/cinnamic acid dioxygenase, ferredoxin subunit RG49_RS22370 f28ad39557289061743829a0c5dd4184 106 Gene3D G3DSA:2.102.10.10 2 104 4.3E-31 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS22370 f28ad39557289061743829a0c5dd4184 106 Pfam PF00355 Rieske [2Fe-2S] domain 4 89 7.9E-18 T 10-03-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 RG49_RS10360 b8a51283083bc94b5e0286ba0c96ebf6 269 SMART SM01252 8 111 6.2E-37 T 10-03-2017 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding RG49_RS10360 b8a51283083bc94b5e0286ba0c96ebf6 269 Pfam PF04383 KilA-N domain 8 108 3.9E-24 T 10-03-2017 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 10-03-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 PRINTS PR00160 Glutaredoxin signature 46 59 3.7E-18 T 10-03-2017 IPR014025 Glutaredoxin subgroup RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 PRINTS PR00160 Glutaredoxin signature 4 22 3.7E-18 T 10-03-2017 IPR014025 Glutaredoxin subgroup RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 PRINTS PR00160 Glutaredoxin signature 60 73 3.7E-18 T 10-03-2017 IPR014025 Glutaredoxin subgroup RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 2.6E-37 T 10-03-2017 IPR011900 Glutaredoxin, GrxC GO:0045454 RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 SUPERFAMILY SSF52833 1 83 5.62E-29 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 Pfam PF00462 Glutaredoxin 4 63 3.2E-24 T 10-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 RG49_RS16355 e8c576ae9b777b43591ed7dca04bcfd9 83 Gene3D G3DSA:3.40.30.10 1 73 4.2E-31 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS19500 5b22fdb04c725f0c1ccf778d2343a6d0 553 SUPERFAMILY SSF117892 61 202 2.62E-23 T 10-03-2017 IPR001107 Band 7 domain RG49_RS19500 5b22fdb04c725f0c1ccf778d2343a6d0 553 Pfam PF15975 Flotillin 406 530 5.4E-37 T 10-03-2017 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 RG49_RS19500 5b22fdb04c725f0c1ccf778d2343a6d0 553 SMART SM00244 30 199 1.5E-25 T 10-03-2017 IPR001107 Band 7 domain RG49_RS19500 5b22fdb04c725f0c1ccf778d2343a6d0 553 Pfam PF01145 SPFH domain / Band 7 family 40 214 4.6E-18 T 10-03-2017 IPR001107 Band 7 domain RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 740 268.722 T 10-03-2017 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 Gene3D G3DSA:1.10.1060.10 333 449 9.2E-18 T 10-03-2017 RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 SUPERFAMILY SSF142019 94 303 4.45E-61 T 10-03-2017 RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 139 283 2.0E-47 T 10-03-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 Pfam PF13375 RnfC Barrel sandwich hybrid domain 14 115 2.3E-33 T 10-03-2017 IPR026902 RnfC Barrel sandwich hybrid domain RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 Pfam PF12838 4Fe-4S dicluster domain 376 430 1.1E-8 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 Pfam PF10531 SLBB domain 296 344 3.5E-12 T 10-03-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 377 388 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 13 445 5.8E-180 T 10-03-2017 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 416 427 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS01905 2ed70f91572b19664bbed37ed5fc9895 740 SUPERFAMILY SSF46548 336 444 6.1E-20 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS20680 516c08379b1bcc380d7970591824fddc 79 Pfam PF09392 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF 9 78 5.6E-26 T 10-03-2017 IPR021123 Type III secretion, needle-protein-like GO:0009405|GO:0015031 RG49_RS20680 516c08379b1bcc380d7970591824fddc 79 TIGRFAM TIGR02105 III_needle: type III secretion apparatus needle protein 6 78 1.5E-31 T 10-03-2017 IPR011841 Type III secretion system, needle protein GO:0008565|GO:0009405|GO:0015031 RG49_RS20680 516c08379b1bcc380d7970591824fddc 79 SUPERFAMILY SSF140129 1 74 4.58E-28 T 10-03-2017 RG49_RS09050 a74b97cb525ada3d7b8a4e8a02f1cdc7 139 SUPERFAMILY SSF48013 3 134 2.35E-42 T 10-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 RG49_RS09050 a74b97cb525ada3d7b8a4e8a02f1cdc7 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 6 131 3.1E-45 T 10-03-2017 IPR011605 NusB antitermination factor GO:0006353 RG49_RS09050 a74b97cb525ada3d7b8a4e8a02f1cdc7 139 Gene3D G3DSA:1.10.940.10 3 135 6.6E-45 T 10-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 RG49_RS09050 a74b97cb525ada3d7b8a4e8a02f1cdc7 139 Pfam PF01029 NusB family 7 131 3.7E-35 T 10-03-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 RG49_RS09050 a74b97cb525ada3d7b8a4e8a02f1cdc7 139 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 4 135 23.572 T 10-03-2017 IPR011605 NusB antitermination factor GO:0006353 RG49_RS07745 671e9a111cf76fc000372e4c0887bf0b 554 Gene3D G3DSA:3.40.50.620 192 510 1.9E-120 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS07745 671e9a111cf76fc000372e4c0887bf0b 554 Pfam PF00733 Asparagine synthase 211 511 5.3E-100 T 10-03-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 RG49_RS07745 671e9a111cf76fc000372e4c0887bf0b 554 SUPERFAMILY SSF56235 1 196 2.92E-58 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS07745 671e9a111cf76fc000372e4c0887bf0b 554 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 371 2.1E-128 T 10-03-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 RG49_RS07745 671e9a111cf76fc000372e4c0887bf0b 554 Gene3D G3DSA:3.60.20.10 2 191 2.9E-68 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS07745 671e9a111cf76fc000372e4c0887bf0b 554 Pfam PF13537 Glutamine amidotransferase domain 48 166 6.5E-42 T 10-03-2017 IPR017932 Glutamine amidotransferase type 2 domain RG49_RS07745 671e9a111cf76fc000372e4c0887bf0b 554 SUPERFAMILY SSF52402 210 479 7.82E-76 T 10-03-2017 RG49_RS10955 75b8e7871c67938515ee3f14a5c26b15 185 Pfam PF01765 Ribosome recycling factor 20 183 6.8E-63 T 10-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 RG49_RS10955 75b8e7871c67938515ee3f14a5c26b15 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.437 T 10-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 RG49_RS10955 75b8e7871c67938515ee3f14a5c26b15 185 SUPERFAMILY SSF55194 2 184 2.09E-71 T 10-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 RG49_RS10955 75b8e7871c67938515ee3f14a5c26b15 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 1.0E-81 T 10-03-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 RG49_RS10955 75b8e7871c67938515ee3f14a5c26b15 185 Gene3D G3DSA:1.10.132.20 67 184 2.9E-44 T 10-03-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 SMART SM00490 517 601 1.7E-19 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 Gene3D G3DSA:3.40.50.300 154 320 4.9E-18 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 SUPERFAMILY SSF52540 141 367 1.07E-36 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 SUPERFAMILY SSF52540 480 654 2.25E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 SUPERFAMILY SSF52540 273 337 2.25E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 SMART SM00487 150 342 1.6E-20 T 10-03-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 Gene3D G3DSA:3.40.50.300 483 627 3.7E-23 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 Pfam PF12137 RNA polymerase recycling family C-terminal 605 965 1.2E-158 T 10-03-2017 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 Pfam PF00176 SNF2 family N-terminal domain 174 441 9.0E-19 T 10-03-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 Pfam PF00271 Helicase conserved C-terminal domain 493 601 3.9E-16 T 10-03-2017 IPR001650 Helicase, C-terminal RG49_RS11580 1c7cff5567c19190aa0e69381c500868 968 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 1 966 74.051 T 10-03-2017 IPR023949 RNA polymerase-associated protein RapA GO:0006355 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 213 234 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 295 312 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 28 51 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 257 276 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 191 212 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 74 96 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 277 295 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 147 170 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 6 26 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 113 138 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 53 73 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 235 256 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 PRINTS PR01002 Flagellar protein FlgJ signature 171 189 4.1E-180 T 10-03-2017 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 Pfam PF10135 Rod binding protein 50 97 9.8E-18 T 10-03-2017 IPR019301 Flagellar protein FlgJ, N-terminal RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 SMART SM00047 142 306 1.9E-73 T 10-03-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 12 295 3.6E-132 T 10-03-2017 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 RG49_RS05240 54abc19c1f181230004e3c23443d7c6a 313 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 161 295 2.3E-20 T 10-03-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 RG49_RS14315 97dd67b940c790b01abcb64aa6bcf9af 257 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 257 25.925 T 10-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS14315 97dd67b940c790b01abcb64aa6bcf9af 257 PIRSF PIRSF000728 1 257 2.6E-74 T 10-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS14315 97dd67b940c790b01abcb64aa6bcf9af 257 Pfam PF00696 Amino acid kinase family 4 234 8.5E-39 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS14315 97dd67b940c790b01abcb64aa6bcf9af 257 SUPERFAMILY SSF53633 2 255 7.59E-62 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS14315 97dd67b940c790b01abcb64aa6bcf9af 257 Gene3D G3DSA:3.40.1160.10 2 256 1.1E-79 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS14315 97dd67b940c790b01abcb64aa6bcf9af 257 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 233 1.6E-78 T 10-03-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 RG49_RS02405 6c205f39a590049039a5099f96aa7029 107 PIRSF PIRSF030771 1 107 3.1E-62 T 10-03-2017 IPR011231 Bacteriophage VT1-Sakai, H0018 RG49_RS02405 6c205f39a590049039a5099f96aa7029 107 Pfam PF09956 Uncharacterized conserved protein (DUF2190) 3 105 1.2E-27 T 10-03-2017 IPR011231 Bacteriophage VT1-Sakai, H0018 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 Gene3D G3DSA:1.10.1740.10 2 108 8.4E-38 T 10-03-2017 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 183 6.8E-32 T 10-03-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 SUPERFAMILY SSF88946 2 105 5.34E-32 T 10-03-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 Gene3D G3DSA:1.10.10.10 122 187 5.2E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 Pfam PF08281 Sigma-70, region 4 129 180 4.4E-19 T 10-03-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 189 3.2E-99 T 10-03-2017 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 Pfam PF04542 Sigma-70 region 2 25 91 4.2E-18 T 10-03-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 SUPERFAMILY SSF88659 122 183 9.53E-19 T 10-03-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS22175 cbc71f42bfa9d5ba628fd0f044c0b4df 191 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 77 - T 10-03-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 RG49_RS11250 5b7dba6fade288e0c70dded82373d87a 264 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 264 175.613 T 10-03-2017 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 RG49_RS11250 5b7dba6fade288e0c70dded82373d87a 264 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 3 261 1.3E-148 T 10-03-2017 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 RG49_RS11250 5b7dba6fade288e0c70dded82373d87a 264 Gene3D G3DSA:3.60.90.10 33 186 5.3E-47 T 10-03-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 RG49_RS11250 5b7dba6fade288e0c70dded82373d87a 264 PIRSF PIRSF001356 1 263 2.6E-156 T 10-03-2017 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 RG49_RS11250 5b7dba6fade288e0c70dded82373d87a 264 Pfam PF02675 S-adenosylmethionine decarboxylase 33 169 2.4E-30 T 10-03-2017 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 RG49_RS11250 5b7dba6fade288e0c70dded82373d87a 264 SUPERFAMILY SSF56276 112 173 5.1E-23 T 10-03-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 RG49_RS11250 5b7dba6fade288e0c70dded82373d87a 264 SUPERFAMILY SSF56276 41 84 5.1E-23 T 10-03-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 RG49_RS06630 cb42febad1a53c8600978e4a4b2bf359 148 Pfam PF05069 Phage virion morphogenesis family 3 146 3.8E-39 T 10-03-2017 IPR006522 Phage virion morphogensis protein RG49_RS06630 cb42febad1a53c8600978e4a4b2bf359 148 TIGRFAM TIGR01635 tail_comp_S: phage virion morphogenesis protein 3 147 3.7E-35 T 10-03-2017 IPR006522 Phage virion morphogensis protein RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 Pfam PF01632 Ribosomal protein L35 2 60 2.3E-22 T 10-03-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 1.2E-26 T 10-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.841 T 10-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 10-03-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-22 T 10-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-22 T 10-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-22 T 10-03-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 RG49_RS01430 fe1a8a3a51c56dbf0860aac70e1d7bd7 65 SUPERFAMILY SSF143034 2 64 3.01E-22 T 10-03-2017 RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 Pfam PF00312 Ribosomal protein S15 9 88 2.2E-38 T 10-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 10-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.443 T 10-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 Gene3D G3DSA:1.10.287.10 3 89 1.0E-39 T 10-03-2017 IPR009068 S15/NS1, RNA-binding RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 6.0E-40 T 10-03-2017 RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 SMART SM01387 8 88 1.8E-52 T 10-03-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 SUPERFAMILY SSF47060 3 89 1.71E-35 T 10-03-2017 IPR009068 S15/NS1, RNA-binding RG49_RS18820 85d82584bc67014d3c63ee6ceabd5751 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 5.7E-41 T 10-03-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS05470 3cbfc0c9fbef801dfbd868b7db9901fa 138 Pfam PF10614 Type VIII secretion system (T8SS), CsgF protein 6 129 2.6E-35 T 10-03-2017 IPR018893 Type VIII secretion system, CsgF RG49_RS02155 a14f98a81c0b073879310c83ed38d3e4 186 Pfam PF13302 Acetyltransferase (GNAT) domain 8 140 7.1E-21 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS02155 a14f98a81c0b073879310c83ed38d3e4 186 Gene3D G3DSA:3.40.630.30 6 166 2.0E-42 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS02155 a14f98a81c0b073879310c83ed38d3e4 186 SUPERFAMILY SSF55729 6 164 9.62E-41 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS12815 9d6fb40bfe2d23d847bfe783e5d17e90 126 Pfam PF01638 HxlR-like helix-turn-helix 29 115 6.0E-32 T 10-03-2017 IPR002577 Helix-turn-helix, HxlR type RG49_RS12815 9d6fb40bfe2d23d847bfe783e5d17e90 126 Gene3D G3DSA:1.10.10.10 3 123 3.2E-45 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12815 9d6fb40bfe2d23d847bfe783e5d17e90 126 SUPERFAMILY SSF46785 13 118 2.25E-32 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS24910 08bac3f34ce808b0e09d364b31be898e 248 TIGRFAM TIGR04009 wcaE: colanic acid biosynthesis glycosyltransferase WcaE 1 248 6.6E-155 T 10-03-2017 IPR024010 Colanic acid biosynthesis, glycosyl transferase, WcaE RG49_RS24910 08bac3f34ce808b0e09d364b31be898e 248 Gene3D G3DSA:3.90.550.10 1 195 4.1E-23 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS24910 08bac3f34ce808b0e09d364b31be898e 248 Pfam PF00535 Glycosyl transferase family 2 4 98 1.8E-12 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS24910 08bac3f34ce808b0e09d364b31be898e 248 SUPERFAMILY SSF53448 2 206 3.56E-28 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 PRINTS PR00050 Cold shock protein signature 43 61 3.4E-17 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 PRINTS PR00050 Cold shock protein signature 7 22 3.4E-17 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 PRINTS PR00050 Cold shock protein signature 28 37 3.4E-17 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 1.7E-31 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 Gene3D G3DSA:2.40.50.140 5 68 5.1E-30 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 SUPERFAMILY SSF50249 3 69 9.66E-26 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 PIRSF PIRSF002599 1 71 6.0E-25 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS02315 fde9de5f8c1d52498f9a5957a8ba432e 71 SMART SM00357 6 70 1.3E-29 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 Gene3D G3DSA:1.10.10.10 6 91 1.6E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 SUPERFAMILY SSF46785 5 114 2.94E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 Gene3D G3DSA:3.40.190.10 92 186 3.5E-22 T 10-03-2017 RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.2E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.2E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.2E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 SUPERFAMILY SSF53850 92 298 4.6E-38 T 10-03-2017 RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 Pfam PF03466 LysR substrate binding domain 91 297 3.1E-38 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 4.2E-20 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS03835 d37553f9670ad89cc54627615aa376c3 302 Gene3D G3DSA:3.40.190.10 187 262 1.5E-9 T 10-03-2017 RG49_RS13675 b94951abfcec35eae32d2fd26d19c5ac 430 SUPERFAMILY SSF141571 251 371 8.11E-19 T 10-03-2017 RG49_RS13675 b94951abfcec35eae32d2fd26d19c5ac 430 Pfam PF00805 Pentapeptide repeats (8 copies) 268 304 1.6E-7 T 10-03-2017 IPR001646 Pentapeptide repeat RG49_RS13675 b94951abfcec35eae32d2fd26d19c5ac 430 Pfam PF00805 Pentapeptide repeats (8 copies) 309 345 7.3E-5 T 10-03-2017 IPR001646 Pentapeptide repeat RG49_RS13675 b94951abfcec35eae32d2fd26d19c5ac 430 Pfam PF13599 Pentapeptide repeats (9 copies) 163 216 2.6E-7 T 10-03-2017 IPR001646 Pentapeptide repeat RG49_RS13675 b94951abfcec35eae32d2fd26d19c5ac 430 SUPERFAMILY SSF141571 146 280 8.63E-24 T 10-03-2017 RG49_RS09165 34ced6a36dc48dc4d72acb1c61942b60 93 ProDom PD029376 YDBD YKIA ECS0442 ECS2009 1 93 4.0E-42 T 10-03-2017 IPR024497 Protein of unknown function DUF2773 RG49_RS09165 34ced6a36dc48dc4d72acb1c61942b60 93 Pfam PF10971 Protein of unknown function (DUF2773) 13 93 1.5E-46 T 10-03-2017 IPR024497 Protein of unknown function DUF2773 RG49_RS02685 76f9d05369187dd2096670e3fcb0656a 440 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 4 103 2.3E-30 T 10-03-2017 IPR017508 HipA, N-terminal subdomain 1 RG49_RS02685 76f9d05369187dd2096670e3fcb0656a 440 Pfam PF13657 HipA N-terminal domain 7 103 9.1E-25 T 10-03-2017 IPR017508 HipA, N-terminal subdomain 1 RG49_RS02685 76f9d05369187dd2096670e3fcb0656a 440 Pfam PF07804 HipA-like C-terminal domain 249 403 3.1E-30 T 10-03-2017 IPR012893 HipA-like, C-terminal RG49_RS02685 76f9d05369187dd2096670e3fcb0656a 440 Pfam PF07805 HipA-like N-terminal domain 150 238 3.5E-19 T 10-03-2017 IPR012894 HipA, N-terminal subdomain 2 RG49_RS00970 d22df89802bfe15266781c04e30c82ba 481 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 2 444 6.1E-114 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS00970 d22df89802bfe15266781c04e30c82ba 481 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 2 444 3.8E-165 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS00970 d22df89802bfe15266781c04e30c82ba 481 ProSitePatterns PS01303 BCCT family of transporters signature. 257 266 - T 10-03-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS07020 b0eedceffb30f153ea5c8d7a52414dd8 361 SUPERFAMILY SSF89733 6 349 2.62E-106 T 10-03-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS07020 b0eedceffb30f153ea5c8d7a52414dd8 361 Gene3D G3DSA:3.30.1370.60 76 280 1.4E-80 T 10-03-2017 RG49_RS07020 b0eedceffb30f153ea5c8d7a52414dd8 361 Pfam PF02615 Malate/L-lactate dehydrogenase 8 338 3.7E-113 T 10-03-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS07020 b0eedceffb30f153ea5c8d7a52414dd8 361 Gene3D G3DSA:1.20.5.460 282 309 5.3E-22 T 10-03-2017 RG49_RS07020 b0eedceffb30f153ea5c8d7a52414dd8 361 Gene3D G3DSA:1.10.1530.10 6 75 6.1E-21 T 10-03-2017 RG49_RS22145 962d4fcebb60e4ebfeeeb772f9870fd3 195 Pfam PF01810 LysE type translocator 15 194 3.8E-14 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS11225 ddcefc5cf7066798d72849925d9a7902 182 Gene3D G3DSA:3.40.50.2020 5 177 1.7E-78 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS11225 ddcefc5cf7066798d72849925d9a7902 182 SUPERFAMILY SSF53271 4 177 1.01E-53 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS11225 ddcefc5cf7066798d72849925d9a7902 182 Pfam PF00156 Phosphoribosyl transferase domain 17 164 3.8E-23 T 10-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 RG49_RS11225 ddcefc5cf7066798d72849925d9a7902 182 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 11 177 1.4E-73 T 10-03-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 RG49_RS05165 f68c11a3b2ca2fd5dc524793b539ab42 269 Gene3D G3DSA:3.30.470.10 1 106 1.4E-32 T 10-03-2017 RG49_RS05165 f68c11a3b2ca2fd5dc524793b539ab42 269 Gene3D G3DSA:3.20.10.10 122 262 4.5E-44 T 10-03-2017 RG49_RS05165 f68c11a3b2ca2fd5dc524793b539ab42 269 SUPERFAMILY SSF56752 2 264 3.27E-70 T 10-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 RG49_RS05165 f68c11a3b2ca2fd5dc524793b539ab42 269 Pfam PF01063 Amino-transferase class IV 24 246 2.1E-48 T 10-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 RG49_RS05165 f68c11a3b2ca2fd5dc524793b539ab42 269 ProSitePatterns PS00770 Aminotransferases class-IV signature. 173 202 - T 10-03-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 RG49_RS05165 f68c11a3b2ca2fd5dc524793b539ab42 269 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 3 262 2.9E-114 T 10-03-2017 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 RG49_RS09655 1c12571461b2f5151078748f4c73a4d8 239 Pfam PF02754 Cysteine-rich domain 133 216 3.1E-14 T 10-03-2017 IPR004017 Cysteine-rich domain RG49_RS09655 1c12571461b2f5151078748f4c73a4d8 239 Pfam PF02754 Cysteine-rich domain 3 84 2.8E-13 T 10-03-2017 IPR004017 Cysteine-rich domain RG49_RS02945 425e740d048be98e59673d7886e22160 336 SUPERFAMILY SSF51735 135 302 2.86E-39 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02945 425e740d048be98e59673d7886e22160 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 3.8E-29 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS02945 425e740d048be98e59673d7886e22160 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 10-03-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 RG49_RS02945 425e740d048be98e59673d7886e22160 336 SUPERFAMILY SSF50129 1 169 4.72E-46 T 10-03-2017 IPR011032 GroES-like RG49_RS02945 425e740d048be98e59673d7886e22160 336 Pfam PF00107 Zinc-binding dehydrogenase 172 298 1.2E-28 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS02945 425e740d048be98e59673d7886e22160 336 SMART SM00829 8 332 1.5E-6 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS02945 425e740d048be98e59673d7886e22160 336 Gene3D G3DSA:3.90.180.10 1 164 3.6E-58 T 10-03-2017 IPR011032 GroES-like RG49_RS02945 425e740d048be98e59673d7886e22160 336 Gene3D G3DSA:3.40.50.720 165 282 1.8E-32 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24655 9ed411025d98b7fdac211e7520c69369 274 Pfam PF03824 High-affinity nickel-transport protein 13 273 1.1E-65 T 10-03-2017 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 RG49_RS03190 00b301637e93d58de57dbf8bb29e9026 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 247 3.2E-13 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03190 00b301637e93d58de57dbf8bb29e9026 264 SUPERFAMILY SSF161098 6 257 4.45E-49 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03190 00b301637e93d58de57dbf8bb29e9026 264 Gene3D G3DSA:1.10.3720.10 9 261 2.8E-49 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS19880 e59f8e3895b83001d3413d02754f122d 304 Gene3D G3DSA:3.40.50.720 2 211 3.7E-47 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS19880 e59f8e3895b83001d3413d02754f122d 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 196 1.9E-20 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS19880 e59f8e3895b83001d3413d02754f122d 304 SUPERFAMILY SSF51735 268 300 2.62E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS19880 e59f8e3895b83001d3413d02754f122d 304 SUPERFAMILY SSF51735 1 241 2.62E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21095 d2e6f2061151d230040633568eedd6e2 260 SUPERFAMILY SSF55120 2 238 1.07E-61 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS21095 d2e6f2061151d230040633568eedd6e2 260 Pfam PF00849 RNA pseudouridylate synthase 11 170 1.5E-28 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS21095 d2e6f2061151d230040633568eedd6e2 260 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 50 64 - T 10-03-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 SUPERFAMILY SSF50249 1 66 8.57E-23 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 PIRSF PIRSF002599 1 74 2.9E-23 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 Gene3D G3DSA:2.40.50.140 1 65 1.9E-29 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 PRINTS PR00050 Cold shock protein signature 25 34 2.8E-16 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-16 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 PRINTS PR00050 Cold shock protein signature 40 58 2.8E-16 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 SMART SM00357 3 67 6.1E-29 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 68 2.1E-43 T 10-03-2017 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 RG49_RS06350 2af9790425e583c73e4c4e65cf6a70d1 74 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 6.4E-29 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS23755 f60b025dbae23e3ebb8e35b400d5830d 153 Pfam PF13673 Acetyltransferase (GNAT) domain 44 149 1.3E-16 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS23755 f60b025dbae23e3ebb8e35b400d5830d 153 SUPERFAMILY SSF55729 1 150 4.69E-34 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS23755 f60b025dbae23e3ebb8e35b400d5830d 153 Gene3D G3DSA:3.40.630.30 2 148 9.7E-48 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS05575 c3167972b4a42808c1f27d2cad0ddb1d 137 ProDom PD460230 MEMBRANE STORAGE INNER HAEMIN SYSTEM HMSS PGA BIOFILM PGAD TRANSMEMBRANE 1 137 8.0E-66 T 10-03-2017 RG49_RS05575 c3167972b4a42808c1f27d2cad0ddb1d 137 Pfam PF13994 PgaD-like protein 4 125 1.8E-16 T 10-03-2017 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 RG49_RS05575 c3167972b4a42808c1f27d2cad0ddb1d 137 TIGRFAM TIGR03940 PGA_PgaD: poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD 3 126 1.4E-15 T 10-03-2017 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 RG49_RS19610 28a8b4a3d9a5ea8750cd2036f45b4819 193 SUPERFAMILY SSF52218 1 192 4.61E-43 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS19610 28a8b4a3d9a5ea8750cd2036f45b4819 193 Pfam PF02525 Flavodoxin-like fold 3 188 1.2E-37 T 10-03-2017 IPR003680 Flavodoxin-like fold RG49_RS19610 28a8b4a3d9a5ea8750cd2036f45b4819 193 Gene3D G3DSA:3.40.50.360 1 192 5.2E-45 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 SUPERFAMILY SSF54292 4 106 7.27E-29 T 10-03-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 Gene3D G3DSA:1.10.1060.10 107 231 6.2E-37 T 10-03-2017 RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 111 3.0E-31 T 10-03-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 Gene3D G3DSA:3.10.20.30 2 106 3.3E-33 T 10-03-2017 IPR012675 Beta-grasp domain RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 10-03-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 Pfam PF13183 4Fe-4S dicluster domain 146 219 7.6E-12 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 SUPERFAMILY SSF46548 107 229 1.92E-31 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS13150 052ebfac67626ca0f2c49ed489e6a56a 244 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 229 4.9E-99 T 10-03-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 Gene3D G3DSA:1.10.10.10 18 167 1.1E-33 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 10-03-2017 IPR023187 Transcriptional regulator MarR-type, conserved site RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 SMART SM00347 46 148 3.0E-31 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 Pfam PF01047 MarR family 53 112 1.4E-16 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 2.4E-24 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 2.4E-24 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 2.4E-24 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 2.4E-24 T 10-03-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 RG49_RS21670 50814fac7a6b49439290e8ccb7977c2b 176 SUPERFAMILY SSF46785 22 166 3.25E-28 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16580 4f8e22a41df9a885a8f3de9ccf4c4266 282 Pfam PF01614 Bacterial transcriptional regulator 143 268 5.3E-45 T 10-03-2017 IPR014757 Transcription regulator IclR, C-terminal RG49_RS16580 4f8e22a41df9a885a8f3de9ccf4c4266 282 Gene3D G3DSA:1.10.10.10 15 91 4.4E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16580 4f8e22a41df9a885a8f3de9ccf4c4266 282 SMART SM00346 23 113 6.4E-41 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS16580 4f8e22a41df9a885a8f3de9ccf4c4266 282 SUPERFAMILY SSF46785 24 97 1.3E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16580 4f8e22a41df9a885a8f3de9ccf4c4266 282 Gene3D G3DSA:3.30.450.40 92 273 9.6E-57 T 10-03-2017 IPR029016 GAF domain-like RG49_RS16580 4f8e22a41df9a885a8f3de9ccf4c4266 282 SUPERFAMILY SSF55781 90 272 5.43E-46 T 10-03-2017 IPR029016 GAF domain-like RG49_RS16580 4f8e22a41df9a885a8f3de9ccf4c4266 282 Pfam PF09339 IclR helix-turn-helix domain 25 74 4.2E-14 T 10-03-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 RG49_RS21265 b4575a2bcaf019d418a408658af2fc71 520 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 6 471 1.0E-99 T 10-03-2017 IPR013381 CRISPR-associated protein Cse1 RG49_RS21265 b4575a2bcaf019d418a408658af2fc71 520 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 5 509 6.9E-184 T 10-03-2017 IPR013381 CRISPR-associated protein Cse1 RG49_RS14115 cbb230cdba77ff99e1a1faee79853dec 631 Pfam PF13667 ThiC-associated domain 27 108 1.0E-32 T 10-03-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 RG49_RS14115 cbb230cdba77ff99e1a1faee79853dec 631 Pfam PF01964 Radical SAM ThiC family 148 596 6.8E-200 T 10-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 RG49_RS14115 cbb230cdba77ff99e1a1faee79853dec 631 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 147 599 2.2E-225 T 10-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 RG49_RS14115 cbb230cdba77ff99e1a1faee79853dec 631 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 147 601 56.158 T 10-03-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 RG49_RS12465 6ceea571b6308d455ec3e91e2da74fc0 238 Gene3D G3DSA:2.40.230.30 25 237 8.9E-69 T 10-03-2017 RG49_RS12465 6ceea571b6308d455ec3e91e2da74fc0 238 Pfam PF06178 Oligogalacturonate-specific porin protein (KdgM) 22 236 7.9E-29 T 10-03-2017 IPR009331 Oligogalacturonate-specific porin RG49_RS15150 dc343b156af7733f266206c0e34d4d10 67 Pfam PF13627 Prokaryotic lipoprotein-attachment site 8 29 6.1E-9 T 10-03-2017 IPR032831 Prokaryotic lipoprotein-attachment site RG49_RS09215 fd26004f3c5a88a00c2fbcf63acbd831 112 Pfam PF07769 psiF repeat 33 65 2.4E-18 T 10-03-2017 IPR011690 Phosphate-starvation-induced PsiF repeat RG49_RS09215 fd26004f3c5a88a00c2fbcf63acbd831 112 Pfam PF07769 psiF repeat 77 109 7.3E-16 T 10-03-2017 IPR011690 Phosphate-starvation-induced PsiF repeat RG49_RS03195 76c746d720ffe64193d2b38cf28c3c52 313 Gene3D G3DSA:1.10.3720.10 78 307 1.5E-41 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03195 76c746d720ffe64193d2b38cf28c3c52 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 307 3.2E-16 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03195 76c746d720ffe64193d2b38cf28c3c52 313 SUPERFAMILY SSF161098 31 307 3.79E-44 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS16095 e4c5e7eb4f39124610131743ba12c8a7 347 SUPERFAMILY SSF48452 129 204 1.3E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16095 e4c5e7eb4f39124610131743ba12c8a7 347 SUPERFAMILY SSF48452 50 85 1.3E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16095 e4c5e7eb4f39124610131743ba12c8a7 347 Gene3D G3DSA:1.25.40.10 49 244 5.2E-14 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22580 b69b4e0c43a05826d05409450abec2ca 463 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 26 325 2.2E-82 T 10-03-2017 IPR014150 Conjugal transfer, TrbL RG49_RS22580 b69b4e0c43a05826d05409450abec2ca 463 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 62 268 2.1E-29 T 10-03-2017 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 RG49_RS10740 f37f9c2a4dd69de5da952f02b40da8d7 240 Pfam PF08241 Methyltransferase domain 71 125 1.4E-10 T 10-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 RG49_RS10740 f37f9c2a4dd69de5da952f02b40da8d7 240 SUPERFAMILY SSF53335 77 207 1.84E-17 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS10740 f37f9c2a4dd69de5da952f02b40da8d7 240 Gene3D G3DSA:3.40.50.150 77 206 2.3E-18 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.432 T 10-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 PIRSF PIRSF002155 1 227 1.9E-78 T 10-03-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.7E-107 T 10-03-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 SUPERFAMILY SSF56808 6 225 4.45E-83 T 10-03-2017 IPR023674 Ribosomal protein L1-like RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 10-03-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 Gene3D G3DSA:3.30.190.20 17 68 5.0E-47 T 10-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 Gene3D G3DSA:3.30.190.20 161 225 5.0E-47 T 10-03-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 4.5E-52 T 10-03-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein RG49_RS14175 aa221aaeffc9e9506e602943921ef46a 234 Gene3D G3DSA:3.40.50.790 69 159 4.7E-41 T 10-03-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich RG49_RS10130 d806873b338ac8ee8d002f928c8a0364 73 Pfam PF06174 Protein of unknown function (DUF987) 1 65 8.3E-40 T 10-03-2017 IPR009329 Protein of unknown function DUF987 RG49_RS10130 d806873b338ac8ee8d002f928c8a0364 73 ProDom PD056719 YEET C0272 C4574 AEC74 ECS1404 C1284 INTERGENIC-REGION YKFH YPJJ 10 73 2.0E-32 T 10-03-2017 IPR009329 Protein of unknown function DUF987 RG49_RS01895 911404ef7490a1d21d8b123e97b38dab 206 SMART SM00900 99 191 1.5E-36 T 10-03-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 RG49_RS01895 911404ef7490a1d21d8b123e97b38dab 206 PIRSF PIRSF006091 1 203 1.1E-70 T 10-03-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 RG49_RS01895 911404ef7490a1d21d8b123e97b38dab 206 Pfam PF04205 FMN-binding domain 99 187 2.9E-19 T 10-03-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 RG49_RS01895 911404ef7490a1d21d8b123e97b38dab 206 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 192 8.9E-70 T 10-03-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 RG49_RS01895 911404ef7490a1d21d8b123e97b38dab 206 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 2 193 26.879 T 10-03-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 RG49_RS17205 0175a85ab238152866d13e1086a5a17d 405 SUPERFAMILY SSF103473 17 396 1.96E-48 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS17205 0175a85ab238152866d13e1086a5a17d 405 Pfam PF07690 Major Facilitator Superfamily 19 120 5.6E-9 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS17205 0175a85ab238152866d13e1086a5a17d 405 Pfam PF07690 Major Facilitator Superfamily 257 400 2.9E-12 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS17205 0175a85ab238152866d13e1086a5a17d 405 Hamap MF_01118 UPF0226 membrane protein . 3 394 29.627 T 10-03-2017 IPR023008 Uncharacterised protein family UPF0226, major facilitator superfamily RG49_RS17205 0175a85ab238152866d13e1086a5a17d 405 Gene3D G3DSA:1.20.1250.20 19 199 1.0E-18 T 10-03-2017 RG49_RS17205 0175a85ab238152866d13e1086a5a17d 405 Gene3D G3DSA:1.20.1250.20 219 397 1.1E-19 T 10-03-2017 RG49_RS15070 38795d3facf63047ab028f62d0851ef1 206 Pfam PF01810 LysE type translocator 14 202 7.1E-51 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS15070 38795d3facf63047ab028f62d0851ef1 206 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 19 200 3.6E-61 T 10-03-2017 IPR004778 Homoserine/Threonine efflux protein GO:0016021 RG49_RS15070 38795d3facf63047ab028f62d0851ef1 206 PIRSF PIRSF006324 1 205 3.4E-55 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS22800 80a9dd33d587548bf4184d4111abf754 66 Pfam PF13980 Uncharacterised protein family (UPF0370) 1 62 4.5E-34 T 10-03-2017 IPR020910 Uncharacterised protein family UPF0370 RG49_RS22800 80a9dd33d587548bf4184d4111abf754 66 Hamap MF_01566 UPF0370 protein YpfN [ypfN]. 1 63 27.722 T 10-03-2017 IPR020910 Uncharacterised protein family UPF0370 RG49_RS14690 444af201730bd8b6d135bb080bb793ae 195 SUPERFAMILY SSF53706 35 195 1.57E-57 T 10-03-2017 RG49_RS14690 444af201730bd8b6d135bb080bb793ae 195 Gene3D G3DSA:2.20.25.90 37 108 6.5E-25 T 10-03-2017 RG49_RS14690 444af201730bd8b6d135bb080bb793ae 195 Pfam PF00384 Molybdopterin oxidoreductase 107 155 2.6E-6 T 10-03-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS14690 444af201730bd8b6d135bb080bb793ae 195 SMART SM00926 43 104 4.9E-22 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS14690 444af201730bd8b6d135bb080bb793ae 195 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 10-03-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 RG49_RS14690 444af201730bd8b6d135bb080bb793ae 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 103 3.7E-19 T 10-03-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS14690 444af201730bd8b6d135bb080bb793ae 195 Gene3D G3DSA:3.40.50.740 109 173 8.9E-16 T 10-03-2017 RG49_RS16195 103142c372162775cb3f2bc874806e02 198 SUPERFAMILY SSF48498 84 193 4.45E-7 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS16195 103142c372162775cb3f2bc874806e02 198 Hamap MF_01839 Nucleoid occlusion factor SlmA [slmA]. 1 198 40.932 T 10-03-2017 IPR023769 Nucleoid occlusion factor SlmA GO:0010974 RG49_RS16195 103142c372162775cb3f2bc874806e02 198 SUPERFAMILY SSF46689 5 86 4.39E-11 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16195 103142c372162775cb3f2bc874806e02 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 61 4.8E-9 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS16195 103142c372162775cb3f2bc874806e02 198 Gene3D G3DSA:1.10.357.10 7 190 2.6E-34 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS16195 103142c372162775cb3f2bc874806e02 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 10-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site RG49_RS09920 0d22507c8268e7d1aee1c55005fab0b0 467 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS09920 0d22507c8268e7d1aee1c55005fab0b0 467 Pfam PF00324 Amino acid permease 18 451 4.1E-115 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS09920 0d22507c8268e7d1aee1c55005fab0b0 467 PIRSF PIRSF006060 1 466 5.0E-86 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS21680 97aeff5a7ac48c263c9c3432825a6690 245 Pfam PF03591 AzlC protein 24 165 2.8E-37 T 10-03-2017 IPR011606 Branched-chain amino acid transport, permease RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 Gene3D G3DSA:3.40.50.10420 189 295 2.8E-54 T 10-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 Gene3D G3DSA:3.40.50.10420 65 128 2.8E-54 T 10-03-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 72 294 5.1E-55 T 10-03-2017 IPR003741 LUD domain RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 Pfam PF13183 4Fe-4S dicluster domain 309 376 8.8E-12 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 SUPERFAMILY SSF46548 282 392 1.03E-18 T 10-03-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 453 3.9E-235 T 10-03-2017 IPR004452 4Fe-4S binding protein GO:0019516 RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 SUPERFAMILY SSF100950 65 89 2.39E-40 T 10-03-2017 RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 SUPERFAMILY SSF100950 135 295 2.39E-40 T 10-03-2017 RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 Pfam PF11870 Domain of unknown function (DUF3390) 385 468 2.0E-11 T 10-03-2017 IPR024569 4Fe-4S binding protein, C-terminal RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 Gene3D G3DSA:1.10.1060.10 305 398 2.6E-13 T 10-03-2017 RG49_RS09650 67ec7930c2d984a92d1d51dfc63193d3 475 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 362 373 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Gene3D G3DSA:3.30.420.40 6 138 2.1E-33 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 420 29.576 T 10-03-2017 IPR020823 Cell division protein FtsA GO:0007049 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 SMART SM00842 10 196 1.1E-96 T 10-03-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Gene3D G3DSA:3.90.640.10 235 297 4.3E-18 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Gene3D G3DSA:3.30.420.40 298 359 1.4E-29 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Gene3D G3DSA:3.30.420.40 210 234 1.4E-29 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 PIRSF PIRSF003101 2 420 5.3E-153 T 10-03-2017 IPR020823 Cell division protein FtsA GO:0007049 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 385 1.2E-161 T 10-03-2017 IPR020823 Cell division protein FtsA GO:0007049 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 SUPERFAMILY SSF53067 8 221 1.94E-61 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 SUPERFAMILY SSF53067 198 384 1.36E-47 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Gene3D G3DSA:3.30.420.40 169 209 1.4E-5 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Pfam PF14450 Cell division protein FtsA 207 381 9.4E-25 T 10-03-2017 RG49_RS11385 7b58e674ba3dcc106ceb417c9db138f7 420 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 4.4E-30 T 10-03-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 RG49_RS17770 03f58a7009ebbdd8f41b157d962431a9 393 Gene3D G3DSA:1.20.1250.20 208 381 1.3E-12 T 10-03-2017 RG49_RS17770 03f58a7009ebbdd8f41b157d962431a9 393 Pfam PF07690 Major Facilitator Superfamily 14 319 9.1E-22 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS17770 03f58a7009ebbdd8f41b157d962431a9 393 Hamap MF_01044 Protein TsgA [tsgA]. 1 388 31.148 T 10-03-2017 IPR023528 Major facilitator superfamily transporter, TsgA RG49_RS17770 03f58a7009ebbdd8f41b157d962431a9 393 Gene3D G3DSA:1.20.1250.20 6 183 1.2E-16 T 10-03-2017 RG49_RS17770 03f58a7009ebbdd8f41b157d962431a9 393 SUPERFAMILY SSF103473 4 385 8.5E-40 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS22140 af241637a7d03f318284ba8a7d712c26 127 Hamap MF_00806 Autonomous glycyl radical cofactor [grcA]. 1 127 43.345 T 10-03-2017 IPR011140 Autonomous glycyl radical cofactor GrcA RG49_RS22140 af241637a7d03f318284ba8a7d712c26 127 TIGRFAM TIGR04365 spare_glycyl: autonomous glycyl radical cofactor GrcA 2 127 1.0E-70 T 10-03-2017 IPR011140 Autonomous glycyl radical cofactor GrcA RG49_RS22140 af241637a7d03f318284ba8a7d712c26 127 ProSitePatterns PS00850 Glycine radical domain signature. 97 105 - T 10-03-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site RG49_RS22140 af241637a7d03f318284ba8a7d712c26 127 PIRSF PIRSF000378 2 127 3.0E-56 T 10-03-2017 IPR011140 Autonomous glycyl radical cofactor GrcA RG49_RS22140 af241637a7d03f318284ba8a7d712c26 127 Pfam PF01228 Glycine radical 16 108 3.2E-22 T 10-03-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 RG49_RS22140 af241637a7d03f318284ba8a7d712c26 127 Gene3D G3DSA:3.20.70.20 35 126 1.6E-34 T 10-03-2017 RG49_RS22140 af241637a7d03f318284ba8a7d712c26 127 SUPERFAMILY SSF51998 64 126 3.25E-24 T 10-03-2017 RG49_RS23585 53125c9d93bd98e258222dccef54316e 180 Pfam PF00293 NUDIX domain 36 154 3.1E-18 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS23585 53125c9d93bd98e258222dccef54316e 180 PIRSF PIRSF017340 1 171 6.7E-76 T 10-03-2017 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 RG49_RS23585 53125c9d93bd98e258222dccef54316e 180 SUPERFAMILY SSF55811 9 166 3.93E-36 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS23585 53125c9d93bd98e258222dccef54316e 180 Gene3D G3DSA:3.90.79.10 2 177 2.3E-63 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 SMART SM00226 3 141 6.3E-68 T 10-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 97 110 8.0E-30 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 113 128 8.0E-30 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 41 57 8.0E-30 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 8.0E-30 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 75 90 8.0E-30 T 10-03-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 Gene3D G3DSA:3.40.50.270 2 145 2.0E-46 T 10-03-2017 RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 SUPERFAMILY SSF52788 1 142 2.75E-44 T 10-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily RG49_RS24880 44e6c4215aea61e17ba2111cbe576c39 147 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 139 2.9E-47 T 10-03-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily RG49_RS05945 53b2039f4bac1280898b2eedf0a04778 586 SUPERFAMILY SSF54211 349 540 2.54E-33 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS05945 53b2039f4bac1280898b2eedf0a04778 586 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 462 481 1.6E-9 T 10-03-2017 RG49_RS05945 53b2039f4bac1280898b2eedf0a04778 586 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 432 451 1.6E-9 T 10-03-2017 RG49_RS05945 53b2039f4bac1280898b2eedf0a04778 586 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 1.6E-9 T 10-03-2017 RG49_RS05945 53b2039f4bac1280898b2eedf0a04778 586 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 435 538 5.5E-10 T 10-03-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 RG49_RS05945 53b2039f4bac1280898b2eedf0a04778 586 Pfam PF13654 AAA domain 140 295 1.2E-19 T 10-03-2017 RG49_RS05945 53b2039f4bac1280898b2eedf0a04778 586 Gene3D G3DSA:3.30.230.10 340 541 5.5E-31 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 21 247 1.3E-84 T 10-03-2017 IPR017788 DnaA regulatory inactivator Hda GO:0032297 RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 Gene3D G3DSA:3.40.50.300 16 179 1.5E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 Gene3D G3DSA:1.10.8.60 182 247 6.6E-31 T 10-03-2017 RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 SUPERFAMILY SSF52540 33 226 8.05E-23 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 Hamap MF_01158 DnaA regulatory inactivator Hda [hda]. 20 248 57.557 T 10-03-2017 IPR022864 DnaA regulatory inactivator Hda, Enterobacteriaceae RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 146 173 1.8E-7 T 10-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 58 78 1.8E-7 T 10-03-2017 IPR020591 Chromosomal replication control, initiator DnaA-like RG49_RS22670 4c7f0457fb24b05f357b7c0347237f04 248 Pfam PF00308 Bacterial dnaA protein 31 227 1.6E-16 T 10-03-2017 IPR013317 Chromosomal replication initiator protein DnaA RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 SUPERFAMILY SSF51246 319 391 3.3E-18 T 10-03-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 SUPERFAMILY SSF52440 3 112 3.31E-36 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 391 52.3 T 10-03-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 SUPERFAMILY SSF56059 113 314 7.78E-56 T 10-03-2017 RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 Gene3D G3DSA:3.40.50.20 5 120 6.1E-41 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 Gene3D G3DSA:3.30.470.20 200 388 1.2E-67 T 10-03-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 391 1.7E-195 T 10-03-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 Pfam PF02222 ATP-grasp domain 123 295 4.3E-57 T 10-03-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type RG49_RS00685 f225bb29ee585e61af6b0bd2c9878d0b 392 Gene3D G3DSA:3.30.1490.20 123 199 7.8E-28 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS09330 284e74edb70dc6c5becf1891a7a0223a 257 TIGRFAM TIGR04390 OMP_YaiO_dom: outer membrane protein, YaiO family 22 257 9.0E-55 T 10-03-2017 IPR030887 YaiO family, OMP domain RG49_RS09330 284e74edb70dc6c5becf1891a7a0223a 257 PIRSF PIRSF007027 1 257 1.3E-164 T 10-03-2017 IPR016504 Uncharacterised conserved protein UCP007027 RG49_RS04735 71b318e3416255f0ca55231b2ea90530 176 Pfam PF02600 Disulfide bond formation protein DsbB 12 159 5.4E-45 T 10-03-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 RG49_RS04735 71b318e3416255f0ca55231b2ea90530 176 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 7 167 22.736 T 10-03-2017 IPR022920 Disulphide bond formation protein DsbB RG49_RS04735 71b318e3416255f0ca55231b2ea90530 176 SUPERFAMILY SSF158442 15 160 4.71E-46 T 10-03-2017 RG49_RS04735 71b318e3416255f0ca55231b2ea90530 176 Gene3D G3DSA:1.20.1550.10 1 174 5.9E-71 T 10-03-2017 IPR023380 Disulphide bond formation protein DsbB-like domain RG49_RS12795 6368f0cdf1a01dc384e1c2397a7d71e6 68 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 1 63 5.0E-30 T 10-03-2017 IPR009491 Protein of unknown function DUF1107 RG49_RS12795 6368f0cdf1a01dc384e1c2397a7d71e6 68 Gene3D G3DSA:3.30.1910.10 1 65 5.0E-37 T 10-03-2017 RG49_RS12795 6368f0cdf1a01dc384e1c2397a7d71e6 68 Pfam PF06526 Protein of unknown function (DUF1107) 1 63 1.1E-29 T 10-03-2017 IPR009491 Protein of unknown function DUF1107 RG49_RS01120 e5ecdc812c6836cde902917f52f82253 278 PIRSF PIRSF001359 1 277 1.7E-76 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS01120 e5ecdc812c6836cde902917f52f82253 278 SUPERFAMILY SSF51569 2 277 2.64E-82 T 10-03-2017 RG49_RS01120 e5ecdc812c6836cde902917f52f82253 278 Gene3D G3DSA:3.20.20.70 2 277 2.0E-91 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS01120 e5ecdc812c6836cde902917f52f82253 278 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 277 4.1E-97 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS01120 e5ecdc812c6836cde902917f52f82253 278 Pfam PF01116 Fructose-bisphosphate aldolase class-II 10 276 1.6E-87 T 10-03-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 RG49_RS04335 ee7c5c3da6a6c1524cfddad9735288b9 98 SUPERFAMILY SSF54909 2 98 3.58E-32 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS04335 ee7c5c3da6a6c1524cfddad9735288b9 98 Gene3D G3DSA:3.30.70.1060 2 98 1.3E-38 T 10-03-2017 RG49_RS04335 ee7c5c3da6a6c1524cfddad9735288b9 98 Pfam PF03795 YCII-related domain 2 95 1.6E-29 T 10-03-2017 IPR005545 YCII-related RG49_RS10020 5b860c5f6f7cf314468b8cc482ac04cd 304 Pfam PF10938 YfdX protein 73 211 3.4E-36 T 10-03-2017 IPR021236 Uncharacterised protein family YfdX RG49_RS02630 427aa761732a9a86719567942d15b274 304 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 1 280 1.3E-56 T 10-03-2017 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 RG49_RS05315 868dc8d0c82e8d87ca65ae7849b70bb2 194 Gene3D G3DSA:3.40.630.30 9 186 8.9E-46 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS05315 868dc8d0c82e8d87ca65ae7849b70bb2 194 Pfam PF13302 Acetyltransferase (GNAT) domain 17 162 5.1E-19 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS05315 868dc8d0c82e8d87ca65ae7849b70bb2 194 SUPERFAMILY SSF55729 12 185 6.07E-42 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 6 457 1.9E-149 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 Gene3D G3DSA:1.20.1250.20 28 208 1.7E-28 T 10-03-2017 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 Gene3D G3DSA:1.20.1250.20 256 458 5.6E-19 T 10-03-2017 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 ProSitePatterns PS00216 Sugar transport proteins signature 1. 314 330 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 PRINTS PR00171 Sugar transporter signature 362 383 5.3E-20 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 PRINTS PR00171 Sugar transporter signature 33 43 5.3E-20 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 PRINTS PR00171 Sugar transporter signature 269 279 5.3E-20 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 PRINTS PR00171 Sugar transporter signature 385 397 5.3E-20 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 PRINTS PR00171 Sugar transporter signature 116 135 5.3E-20 T 10-03-2017 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 ProSitePatterns PS00217 Sugar transport proteins signature 2. 121 146 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 Pfam PF00083 Sugar (and other) transporter 26 460 7.8E-133 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS20820 4ca9c137e2fb78d8fa4a7902275e4e0a 472 SUPERFAMILY SSF103473 16 459 3.79E-72 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS10445 62676f41d2690a0d15bcf75ea9da932a 116 ProDom PD031037 EXCISIONASE DNA-BINDING DNA XIS RECOMBINATION SHIGELLA P40 X PROBABLE GP35 1 112 6.0E-61 T 10-03-2017 RG49_RS10445 62676f41d2690a0d15bcf75ea9da932a 116 Pfam PF12728 Helix-turn-helix domain 6 35 8.6E-8 T 10-03-2017 RG49_RS13715 1e90af2a760a07849fb213a40f495859 528 SUPERFAMILY SSF141868 274 520 1.31E-78 T 10-03-2017 IPR001633 EAL domain RG49_RS13715 1e90af2a760a07849fb213a40f495859 528 SMART SM00052 267 511 6.2E-124 T 10-03-2017 IPR001633 EAL domain RG49_RS13715 1e90af2a760a07849fb213a40f495859 528 Pfam PF00563 EAL domain 273 505 3.2E-71 T 10-03-2017 IPR001633 EAL domain RG49_RS13715 1e90af2a760a07849fb213a40f495859 528 Gene3D G3DSA:3.20.20.450 273 518 3.9E-86 T 10-03-2017 IPR001633 EAL domain RG49_RS13715 1e90af2a760a07849fb213a40f495859 528 Pfam PF12792 CSS motif domain associated with EAL 40 243 2.3E-40 T 10-03-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain RG49_RS10510 5d75622d7c2b8b5ddb7d4f11c04259e1 132 ProDom PD082093 YAFO SIMILAR YAFO-LIKE UNCHARACTERIZED PROTEIN ESCHERICHIA ECS0260 COLI 1 132 8.0E-74 T 10-03-2017 IPR020353 Toxin YafO RG49_RS10510 5d75622d7c2b8b5ddb7d4f11c04259e1 132 Pfam PF13957 Toxin YafO, type II toxin-antitoxin system 27 130 7.2E-36 T 10-03-2017 IPR020353 Toxin YafO RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 SUPERFAMILY SSF53067 13 190 2.1E-36 T 10-03-2017 RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 Gene3D G3DSA:3.30.420.40 11 189 7.1E-38 T 10-03-2017 RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 Gene3D G3DSA:2.40.128.130 277 603 9.6E-90 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 188 603 1.7E-108 T 10-03-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 Gene3D G3DSA:2.160.20.20 190 268 1.1E-18 T 10-03-2017 IPR012332 P22 tailspike C-terminal domain-like RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 Pfam PF03212 Pertactin 189 249 1.1E-4 T 10-03-2017 IPR004899 Pertactin, central region RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 SUPERFAMILY SSF103515 286 603 3.14E-50 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 SUPERFAMILY SSF51126 188 250 6.28E-13 T 10-03-2017 IPR011050 Pectin lyase fold/virulence factor RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 13 190 3.6E-27 T 10-03-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 SMART SM00869 319 592 2.1E-46 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS02675 7075a6e62bb9426ff829c2d69d11cf00 603 Pfam PF03797 Autotransporter beta-domain 317 588 2.4E-53 T 10-03-2017 IPR005546 Autotransporter beta-domain RG49_RS13485 0c7c2b6d470eebc77305ff02c7f9df4d 281 PIRSF PIRSF011468 1 281 1.8E-169 T 10-03-2017 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399 RG49_RS13485 0c7c2b6d470eebc77305ff02c7f9df4d 281 Pfam PF06007 Phosphonate metabolism protein PhnJ 6 277 5.8E-149 T 10-03-2017 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399 RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 15 792 0.0 T 10-03-2017 IPR017511 PQQ-dependent membrane bound dehydrogenase, glucose/quinate/shikimate-related GO:0016021|GO:0016614|GO:0048038|GO:0055114 RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Pfam PF01011 PQQ enzyme repeat 225 258 6.6E-8 T 10-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Pfam PF01011 PQQ enzyme repeat 721 758 5.1E-6 T 10-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Pfam PF01011 PQQ enzyme repeat 442 468 9.2E-7 T 10-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Pfam PF01011 PQQ enzyme repeat 289 321 3.8E-4 T 10-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Pfam PF01011 PQQ enzyme repeat 357 387 2.4E-5 T 10-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Pfam PF01011 PQQ enzyme repeat 664 696 2.0E-7 T 10-03-2017 IPR002372 Pyrrolo-quinoline quinone repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Gene3D G3DSA:2.140.10.10 159 533 7.5E-164 T 10-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 Gene3D G3DSA:2.140.10.10 568 793 7.5E-164 T 10-03-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 ProSitePatterns PS00363 Bacterial quinoprotein dehydrogenases signature 1. 167 195 - T 10-03-2017 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 404 425 - T 10-03-2017 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SMART SM00564 339 380 0.16 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SMART SM00564 401 458 310.0 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SMART SM00564 715 748 0.04 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SMART SM00564 282 314 210.0 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SMART SM00564 220 251 2.4E-6 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SMART SM00564 479 512 550.0 T 10-03-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SUPERFAMILY SSF50998 161 521 5.36E-158 T 10-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily RG49_RS11230 6c0c29cc49bbb6128434e2f5e33eddf8 796 SUPERFAMILY SSF50998 557 792 5.36E-158 T 10-03-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily RG49_RS08595 4f52cdecd6ba96f0da8386afa0a8d56d 228 SUPERFAMILY SSF52540 6 226 1.25E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08595 4f52cdecd6ba96f0da8386afa0a8d56d 228 Gene3D G3DSA:3.40.50.300 5 227 5.5E-69 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS08595 4f52cdecd6ba96f0da8386afa0a8d56d 228 SMART SM00382 35 225 3.9E-16 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS08595 4f52cdecd6ba96f0da8386afa0a8d56d 228 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS08595 4f52cdecd6ba96f0da8386afa0a8d56d 228 Pfam PF00005 ABC transporter 27 174 1.0E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 426 5.4E-220 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 Pfam PF02040 Arsenical pump membrane protein 3 423 1.0E-159 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS17030 e0c8c878f166338d72ff6cbc60ef55cb 429 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 4.2E-123 T 10-03-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 RG49_RS21160 e7fba6e90ad701a2b994014b0bb805e6 290 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 29 152 2.9E-34 T 10-03-2017 IPR007621 TPM domain RG49_RS15230 841c5204136ea32468432b62f37eaee1 461 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS15230 841c5204136ea32468432b62f37eaee1 461 PIRSF PIRSF006060 1 461 1.7E-65 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS15230 841c5204136ea32468432b62f37eaee1 461 Pfam PF00324 Amino acid permease 16 428 2.5E-103 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS22705 e89ea5f410a73899636265143c0084d6 252 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 127 143 - T 10-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22705 e89ea5f410a73899636265143c0084d6 252 Gene3D G3DSA:3.40.50.700 34 156 3.1E-24 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22705 e89ea5f410a73899636265143c0084d6 252 SUPERFAMILY SSF56770 32 163 5.36E-46 T 10-03-2017 RG49_RS22705 e89ea5f410a73899636265143c0084d6 252 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 44 151 8.3E-20 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS08050 a27ce1a7c7f7369ee4e47a9563e148fa 292 Hamap MF_00397 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [citG]. 3 292 183.487 T 10-03-2017 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 RG49_RS08050 a27ce1a7c7f7369ee4e47a9563e148fa 292 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 26 290 1.1E-81 T 10-03-2017 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 RG49_RS08050 a27ce1a7c7f7369ee4e47a9563e148fa 292 TIGRFAM TIGR03125 citrate_citG: triphosphoribosyl-dephospho-CoA synthase CitG 21 291 2.1E-109 T 10-03-2017 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 RG49_RS02800 544c6be5df02a4efb6d41182aadbaa32 176 SUPERFAMILY SSF49401 33 176 1.44E-33 T 10-03-2017 IPR008966 Adhesion domain RG49_RS02800 544c6be5df02a4efb6d41182aadbaa32 176 Pfam PF00419 Fimbrial protein 29 176 9.4E-19 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS02800 544c6be5df02a4efb6d41182aadbaa32 176 Gene3D G3DSA:2.60.40.1090 27 176 2.0E-39 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11885 13fe4258b37e32edda386faa50ec5fdf 21 TIGRFAM TIGR02077 thr_lead_pep: thr operon leader peptide 1 21 2.2E-9 T 10-03-2017 IPR011720 Thr operon leader peptide GO:0009088|GO:0031554|GO:0031556 RG49_RS11885 13fe4258b37e32edda386faa50ec5fdf 21 Pfam PF08254 Threonine leader peptide 1 21 4.9E-10 T 10-03-2017 IPR011720 Thr operon leader peptide GO:0009088|GO:0031554|GO:0031556 RG49_RS11885 13fe4258b37e32edda386faa50ec5fdf 21 Hamap MF_01907 Thr operon leader peptide [thrL]. 1 21 11.934 T 10-03-2017 IPR011720 Thr operon leader peptide GO:0009088|GO:0031554|GO:0031556 RG49_RS01770 1cd0fb3dc2ddc3cce68fee0e9c994807 271 SUPERFAMILY SSF54001 133 265 1.24E-41 T 10-03-2017 RG49_RS01770 1cd0fb3dc2ddc3cce68fee0e9c994807 271 Gene3D G3DSA:3.90.1720.10 133 266 2.2E-47 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS01770 1cd0fb3dc2ddc3cce68fee0e9c994807 271 Pfam PF00877 NlpC/P60 family 153 263 3.8E-33 T 10-03-2017 IPR000064 Endopeptidase, NLPC/P60 domain RG49_RS15380 a4c4ff7d036b31794f438746bc460e3d 32 Pfam PF08046 IlvGEDA operon leader peptide 1 32 1.5E-17 T 10-03-2017 IPR012567 IlvGEDA operon leader peptide GO:0009082 RG49_RS18975 48597c0a2b3cc20f9a6fc6a41c67c758 384 SUPERFAMILY SSF53697 15 373 2.23E-53 T 10-03-2017 RG49_RS18975 48597c0a2b3cc20f9a6fc6a41c67c758 384 Gene3D G3DSA:3.40.50.10490 199 376 4.5E-52 T 10-03-2017 RG49_RS18975 48597c0a2b3cc20f9a6fc6a41c67c758 384 Pfam PF01380 SIS domain 48 188 4.3E-31 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS18975 48597c0a2b3cc20f9a6fc6a41c67c758 384 Pfam PF01380 SIS domain 221 357 2.7E-24 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS18975 48597c0a2b3cc20f9a6fc6a41c67c758 384 Gene3D G3DSA:3.40.50.10490 12 194 1.5E-68 T 10-03-2017 RG49_RS18975 48597c0a2b3cc20f9a6fc6a41c67c758 384 TIGRFAM TIGR02815 agaS_fam: putative sugar isomerase, AgaS family 13 382 1.0E-191 T 10-03-2017 IPR014180 Sugar isomerase, AgaS GO:0016861 RG49_RS12650 0ddc8911d5b6915a314e1c7167bbe1e8 131 Gene3D G3DSA:3.30.1330.40 14 130 8.6E-40 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS12650 0ddc8911d5b6915a314e1c7167bbe1e8 131 SUPERFAMILY SSF55298 7 130 8.17E-35 T 10-03-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like RG49_RS12650 0ddc8911d5b6915a314e1c7167bbe1e8 131 Pfam PF01042 Endoribonuclease L-PSP 13 127 1.9E-30 T 10-03-2017 IPR006175 YjgF/YER057c/UK114 family RG49_RS01620 d02e27382ec352e8efea9dc1184bbb95 495 Pfam PF01458 Uncharacterized protein family (UPF0051) 234 466 8.0E-69 T 10-03-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 RG49_RS01620 d02e27382ec352e8efea9dc1184bbb95 495 SUPERFAMILY SSF101960 41 86 2.75E-137 T 10-03-2017 RG49_RS01620 d02e27382ec352e8efea9dc1184bbb95 495 SUPERFAMILY SSF101960 125 492 2.75E-137 T 10-03-2017 RG49_RS01620 d02e27382ec352e8efea9dc1184bbb95 495 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 21 486 5.8E-194 T 10-03-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 17 33 - T 10-03-2017 IPR013061 Tryptophan/tryrosine permease, conserved site RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 Pfam PF03222 Tryptophan/tyrosine permease family 3 390 6.6E-143 T 10-03-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 337 356 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 37 56 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 82 102 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 182 204 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 282 301 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 316 334 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 10 33 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 148 168 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 PRINTS PR00166 Aromatic amino acid permease signature 221 240 2.9E-92 T 10-03-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 RG49_RS00375 7bc0698336eded520bf4434443e25a78 403 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 7 384 1.5E-147 T 10-03-2017 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 RG49_RS19275 04c481f17b924655e766588a3afcc79c 230 Gene3D G3DSA:3.40.50.620 74 172 1.1E-10 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS19275 04c481f17b924655e766588a3afcc79c 230 Pfam PF02698 DUF218 domain 64 176 4.8E-20 T 10-03-2017 IPR003848 Domain of unknown function DUF218 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 10-03-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 SUPERFAMILY SSF51905 97 261 2.07E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 SUPERFAMILY SSF51905 7 66 2.07E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 Gene3D G3DSA:3.50.50.60 7 233 3.1E-56 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 Pfam PF01134 Glucose inhibited division protein A 8 398 8.0E-171 T 10-03-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 Pfam PF13932 GidA associated domain 403 616 2.6E-73 T 10-03-2017 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 SMART SM01228 546 617 9.2E-45 T 10-03-2017 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 0.0 T 10-03-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 10-03-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 RG49_RS15505 4a322e9c133bccec0d2cf7d3cec1e706 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 43.099 T 10-03-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 15 427 4.4E-157 T 10-03-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Hamap MF_00671 Protein TolB [tolB]. 5 426 34.523 T 10-03-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 SUPERFAMILY SSF52964 29 161 4.84E-40 T 10-03-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Gene3D G3DSA:2.130.10.10 155 428 9.0E-75 T 10-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 SUPERFAMILY SSF69304 155 428 7.98E-56 T 10-03-2017 RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Pfam PF07676 WD40-like Beta Propeller Repeat 281 315 4.3E-10 T 10-03-2017 IPR011659 WD40-like Beta Propeller RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Pfam PF07676 WD40-like Beta Propeller Repeat 199 223 4.2E-5 T 10-03-2017 IPR011659 WD40-like Beta Propeller RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Pfam PF07676 WD40-like Beta Propeller Repeat 369 396 0.0031 T 10-03-2017 IPR011659 WD40-like Beta Propeller RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Pfam PF07676 WD40-like Beta Propeller Repeat 237 272 1.8E-9 T 10-03-2017 IPR011659 WD40-like Beta Propeller RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Gene3D G3DSA:3.40.50.10070 22 154 4.0E-51 T 10-03-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 RG49_RS07345 5506f1e2c28b9da3d0e59cb3d8ba2457 430 Pfam PF04052 TolB amino-terminal domain 23 121 4.5E-31 T 10-03-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 RG49_RS17370 526b62c51f4d9665cb1c18178678e827 162 Gene3D G3DSA:3.40.630.30 2 160 2.6E-40 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS17370 526b62c51f4d9665cb1c18178678e827 162 Pfam PF00583 Acetyltransferase (GNAT) family 57 137 4.0E-14 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS17370 526b62c51f4d9665cb1c18178678e827 162 SUPERFAMILY SSF55729 4 161 5.57E-36 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS21180 51e483eec8f6938c81e27861bb1a97d2 425 Gene3D G3DSA:1.20.1250.20 215 408 5.6E-7 T 10-03-2017 RG49_RS21180 51e483eec8f6938c81e27861bb1a97d2 425 Pfam PF07690 Major Facilitator Superfamily 26 362 2.4E-22 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS21180 51e483eec8f6938c81e27861bb1a97d2 425 SUPERFAMILY SSF103473 5 413 1.96E-38 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS21180 51e483eec8f6938c81e27861bb1a97d2 425 Gene3D G3DSA:1.20.1250.20 8 197 1.3E-20 T 10-03-2017 RG49_RS22885 4c230c6514cdc384596566f76e37b4e9 97 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 2 48 7.0E-19 T 10-03-2017 RG49_RS22885 4c230c6514cdc384596566f76e37b4e9 97 Pfam PF00936 BMC domain 3 78 8.2E-28 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS22885 4c230c6514cdc384596566f76e37b4e9 97 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 20 39 - T 10-03-2017 IPR020808 Bacterial microcompartments protein, conserved site RG49_RS22885 4c230c6514cdc384596566f76e37b4e9 97 SUPERFAMILY SSF143414 1 89 2.35E-31 T 10-03-2017 RG49_RS22885 4c230c6514cdc384596566f76e37b4e9 97 SMART SM00877 2 78 9.9E-36 T 10-03-2017 IPR000249 Microcompartment protein, bacteria RG49_RS10850 840a02f89b25b531d46615add518a845 236 Pfam PF04170 NlpE N-terminal domain 45 130 5.7E-27 T 10-03-2017 IPR007298 Copper resistance lipoprotein NlpE RG49_RS10850 840a02f89b25b531d46615add518a845 236 Pfam PF17185 NlpE C-terminal OB domain 144 232 1.1E-32 T 10-03-2017 IPR033450 NlpE, C-terminal OB domain RG49_RS20110 c936518c8f11c632740dce51e9e2ffe2 378 SMART SM00729 6 223 3.6E-55 T 10-03-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 RG49_RS20110 c936518c8f11c632740dce51e9e2ffe2 378 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 368 2.7E-141 T 10-03-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 RG49_RS20110 c936518c8f11c632740dce51e9e2ffe2 378 Gene3D G3DSA:3.80.30.20 7 239 7.4E-29 T 10-03-2017 IPR023404 Radical SAM, alpha/beta horseshoe RG49_RS20110 c936518c8f11c632740dce51e9e2ffe2 378 SUPERFAMILY SSF102114 5 376 2.88E-107 T 10-03-2017 RG49_RS20110 c936518c8f11c632740dce51e9e2ffe2 378 Pfam PF04055 Radical SAM superfamily 11 177 6.1E-19 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS20110 c936518c8f11c632740dce51e9e2ffe2 378 Pfam PF06969 HemN C-terminal domain 304 364 5.2E-8 T 10-03-2017 IPR010723 HemN, C-terminal RG49_RS21430 d73a340c291028eb0358e0413d694dbf 373 PIRSF PIRSF005622 1 372 4.3E-160 T 10-03-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 RG49_RS21430 d73a340c291028eb0358e0413d694dbf 373 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 371 3.9E-180 T 10-03-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 RG49_RS21430 d73a340c291028eb0358e0413d694dbf 373 Pfam PF01924 Hydrogenase formation hypA family 15 367 9.4E-152 T 10-03-2017 IPR002780 Hydrogenase formation HypD protein GO:0046872 RG49_RS05135 2f8b48b22b75611153bfbf8644138bc0 640 Gene3D G3DSA:2.40.170.20 103 640 1.8E-133 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS05135 2f8b48b22b75611153bfbf8644138bc0 640 SUPERFAMILY SSF56935 1 640 7.06E-111 T 10-03-2017 RG49_RS05135 2f8b48b22b75611153bfbf8644138bc0 640 Gene3D G3DSA:2.170.130.10 1 94 9.5E-21 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS05135 2f8b48b22b75611153bfbf8644138bc0 640 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 623 640 - T 10-03-2017 IPR010917 TonB-dependent receptor, conserved site RG49_RS05135 2f8b48b22b75611153bfbf8644138bc0 640 Pfam PF07715 TonB-dependent Receptor Plug Domain 1 86 8.9E-8 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS05135 2f8b48b22b75611153bfbf8644138bc0 640 Pfam PF00593 TonB dependent receptor 404 639 7.2E-31 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS05135 2f8b48b22b75611153bfbf8644138bc0 640 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 1 640 4.5E-172 T 10-03-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 Gene3D G3DSA:3.40.140.10 2 128 5.1E-38 T 10-03-2017 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 146 364 1.3E-83 T 10-03-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 99 5.4E-24 T 10-03-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 SUPERFAMILY SSF53927 3 145 1.84E-50 T 10-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 SUPERFAMILY SSF53597 144 362 4.06E-58 T 10-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 PIRSF PIRSF006769 1 367 1.3E-141 T 10-03-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 362 2.1E-160 T 10-03-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 10-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 Pfam PF01872 RibD C-terminal domain 147 362 6.2E-64 T 10-03-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 RG49_RS09060 f298dc2a157fb812fdfbe9d48b33fedb 367 Gene3D G3DSA:3.40.430.10 129 363 4.2E-70 T 10-03-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 RG49_RS13310 2b5f1c1b38a8e69a6bcb5dce2d9bf6f2 90 SUPERFAMILY SSF55729 2 88 4.58E-23 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS13310 2b5f1c1b38a8e69a6bcb5dce2d9bf6f2 90 Gene3D G3DSA:3.40.630.30 1 89 3.7E-33 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS13310 2b5f1c1b38a8e69a6bcb5dce2d9bf6f2 90 Pfam PF14542 GCN5-related N-acetyl-transferase 9 88 2.0E-21 T 10-03-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase RG49_RS03325 076eb144eb4ed579bce42ec9beee5823 176 Pfam PF01292 Prokaryotic cytochrome b561 4 172 2.1E-21 T 10-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 RG49_RS03325 076eb144eb4ed579bce42ec9beee5823 176 SUPERFAMILY SSF81342 4 172 5.89E-28 T 10-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 RG49_RS17305 37548f635b68dea3138128a61e47bfbc 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS17305 37548f635b68dea3138128a61e47bfbc 237 PIRSF PIRSF039137 1 237 4.3E-104 T 10-03-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 RG49_RS17305 37548f635b68dea3138128a61e47bfbc 237 SMART SM00382 30 216 6.7E-4 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS17305 37548f635b68dea3138128a61e47bfbc 237 Gene3D G3DSA:3.40.50.300 2 232 1.7E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17305 37548f635b68dea3138128a61e47bfbc 237 Pfam PF00005 ABC transporter 21 165 2.4E-33 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS17305 37548f635b68dea3138128a61e47bfbc 237 SUPERFAMILY SSF52540 4 234 8.31E-61 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14520 2d0b7132078823aa49193912d70fce18 146 Pfam PF05656 Protein of unknown function (DUF805) 8 132 1.2E-21 T 10-03-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 RG49_RS07950 95df53110b4b0bff22f15b71a45ee620 87 SUPERFAMILY SSF117991 1 87 3.4E-31 T 10-03-2017 IPR027471 YbeD-like domain RG49_RS07950 95df53110b4b0bff22f15b71a45ee620 87 Pfam PF04359 Protein of unknown function (DUF493) 7 87 5.6E-29 T 10-03-2017 IPR007454 Uncharacterised protein family UPF0250 RG49_RS07950 95df53110b4b0bff22f15b71a45ee620 87 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 1 87 26.681 T 10-03-2017 IPR007454 Uncharacterised protein family UPF0250 RG49_RS07950 95df53110b4b0bff22f15b71a45ee620 87 Gene3D G3DSA:3.30.70.1460 1 87 1.8E-37 T 10-03-2017 IPR027471 YbeD-like domain RG49_RS24170 f1802769da8c9cc2c67c3a32eecbac06 350 Gene3D G3DSA:1.25.40.10 260 343 1.2E-28 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS24170 f1802769da8c9cc2c67c3a32eecbac06 350 SUPERFAMILY SSF48452 218 327 2.04E-19 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS24170 f1802769da8c9cc2c67c3a32eecbac06 350 Pfam PF03918 Cytochrome C biogenesis protein 7 129 7.6E-51 T 10-03-2017 IPR005616 CcmH/CycL/Ccl2/NrfF family RG49_RS24170 f1802769da8c9cc2c67c3a32eecbac06 350 Gene3D G3DSA:1.25.40.10 194 259 6.5E-7 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS10185 ef69b4f045183e401ca0094e3f053dd8 147 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 10 142 3.1E-25 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS20090 d7dbb589369144842b0aeadbbe674330 108 Pfam PF04320 Protein with unknown function (DUF469) 7 107 1.6E-43 T 10-03-2017 IPR007416 Protein of unknown function DUF469 RG49_RS16125 3ff4cae3eab8617935adc1d51c352d85 463 Pfam PF00860 Permease family 34 426 1.8E-112 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS16125 3ff4cae3eab8617935adc1d51c352d85 463 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 29 457 7.3E-143 T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS16125 3ff4cae3eab8617935adc1d51c352d85 463 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 375 395 - T 10-03-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 Gene3D G3DSA:1.10.3410.10 269 390 4.6E-34 T 10-03-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 502 7.8E-150 T 10-03-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 Gene3D G3DSA:1.10.3210.10 4 122 1.1E-71 T 10-03-2017 IPR006674 HD domain RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 Gene3D G3DSA:1.10.3210.10 183 268 1.1E-71 T 10-03-2017 IPR006674 HD domain RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 SUPERFAMILY SSF109604 251 432 1.2E-67 T 10-03-2017 RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 SUPERFAMILY SSF109604 31 134 1.2E-67 T 10-03-2017 RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 SUPERFAMILY SSF109604 182 215 1.2E-67 T 10-03-2017 RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 SUPERFAMILY SSF109604 483 501 1.2E-67 T 10-03-2017 RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 Pfam PF01966 HD domain 66 146 2.0E-10 T 10-03-2017 IPR006674 HD domain RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 Gene3D G3DSA:1.10.3550.10 123 158 1.1E-32 T 10-03-2017 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 Gene3D G3DSA:1.10.3550.10 391 503 1.1E-32 T 10-03-2017 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 SMART SM00471 62 282 2.4E-11 T 10-03-2017 IPR003607 HD/PDEase domain RG49_RS11025 e325bd2f5aec142ebd23eec7dc623ac4 505 Hamap MF_00030 Deoxyguanosinetriphosphate triphosphohydrolase [dgt]. 1 504 51.65 T 10-03-2017 IPR020779 Deoxyguanosinetriphosphate triphosphohydrolase, proteobacteria GO:0000287|GO:0006203|GO:0008832 KEGG: 00230+3.1.5.1 RG49_RS11120 2c36861317083480fd2b95498467ded2 159 Gene3D G3DSA:3.30.70.560 3 150 1.5E-57 T 10-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS11120 2c36861317083480fd2b95498467ded2 159 SUPERFAMILY SSF55083 1 152 8.11E-54 T 10-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS11120 2c36861317083480fd2b95498467ded2 159 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 10-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS11120 2c36861317083480fd2b95498467ded2 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 134 5.2E-36 T 10-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS11120 2c36861317083480fd2b95498467ded2 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 134 2.8E-47 T 10-03-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 RG49_RS05480 4e5d3bfea4ed60f38e8d2ad4b0effd9f 173 Pfam PF06496 Protein of unknown function (DUF1097) 18 152 2.0E-38 T 10-03-2017 IPR009476 Protein of unknown function DUF1097 RG49_RS04320 7e6505cd3b62bd795c957ca416f31030 179 Pfam PF04279 Intracellular septation protein A 1 175 1.1E-72 T 10-03-2017 IPR006008 Intracellular septation protein A GO:0016021 RG49_RS04320 7e6505cd3b62bd795c957ca416f31030 179 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 178 3.3E-75 T 10-03-2017 IPR006008 Intracellular septation protein A GO:0016021 RG49_RS04320 7e6505cd3b62bd795c957ca416f31030 179 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 176 19.531 T 10-03-2017 IPR006008 Intracellular septation protein A GO:0016021 RG49_RS07925 e1cf7bcdabbdf66cf859974522a5a4b9 155 SUPERFAMILY SSF75217 2 153 3.51E-50 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS07925 e1cf7bcdabbdf66cf859974522a5a4b9 155 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 155 1.7E-87 T 10-03-2017 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS07925 e1cf7bcdabbdf66cf859974522a5a4b9 155 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 154 27.079 T 10-03-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS07925 e1cf7bcdabbdf66cf859974522a5a4b9 155 PIRSF PIRSF004505 1 154 6.1E-40 T 10-03-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS07925 e1cf7bcdabbdf66cf859974522a5a4b9 155 Gene3D G3DSA:3.40.1280.10 2 154 5.5E-53 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS07925 e1cf7bcdabbdf66cf859974522a5a4b9 155 Pfam PF02590 Predicted SPOUT methyltransferase 2 153 2.9E-46 T 10-03-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 RG49_RS13785 a449fea1395713e6b35eafe5ab34a037 345 SUPERFAMILY SSF51395 27 335 2.56E-71 T 10-03-2017 RG49_RS13785 a449fea1395713e6b35eafe5ab34a037 345 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 26 342 1.7E-174 T 10-03-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 RG49_RS13785 a449fea1395713e6b35eafe5ab34a037 345 Pfam PF01207 Dihydrouridine synthase (Dus) 30 339 3.0E-100 T 10-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS13785 a449fea1395713e6b35eafe5ab34a037 345 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 10-03-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS13785 a449fea1395713e6b35eafe5ab34a037 345 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 22 343 52.866 T 10-03-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 RG49_RS13785 a449fea1395713e6b35eafe5ab34a037 345 PIRSF PIRSF006621 16 341 9.4E-72 T 10-03-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 RG49_RS13785 a449fea1395713e6b35eafe5ab34a037 345 Gene3D G3DSA:3.20.20.70 24 267 2.7E-75 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 Pfam PF13185 GAF domain 17 155 1.8E-8 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 Gene3D G3DSA:3.30.450.40 5 169 1.4E-16 T 10-03-2017 IPR029016 GAF domain-like RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 Pfam PF00990 Diguanylate cyclase, GGDEF domain 175 330 2.0E-41 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 SMART SM00267 163 335 1.2E-53 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 SUPERFAMILY SSF55073 179 331 1.18E-38 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 SMART SM00065 18 164 7.0E-17 T 10-03-2017 IPR003018 GAF domain GO:0005515 RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 Gene3D G3DSA:3.30.70.270 175 337 3.1E-44 T 10-03-2017 RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 172 334 3.9E-37 T 10-03-2017 IPR000160 GGDEF domain RG49_RS01015 5e843cb09238e61f6cae5adf9ee64d91 341 SUPERFAMILY SSF55781 18 167 5.67E-17 T 10-03-2017 IPR029016 GAF domain-like RG49_RS15570 3fb2549c0452e2100be49f3a0d2cffea 346 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 335 5.5E-127 T 10-03-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 RG49_RS15570 3fb2549c0452e2100be49f3a0d2cffea 346 Gene3D G3DSA:3.40.190.10 27 177 4.2E-56 T 10-03-2017 RG49_RS15570 3fb2549c0452e2100be49f3a0d2cffea 346 Gene3D G3DSA:3.40.190.10 181 338 2.8E-36 T 10-03-2017 RG49_RS15570 3fb2549c0452e2100be49f3a0d2cffea 346 SUPERFAMILY SSF53850 27 339 6.04E-98 T 10-03-2017 RG49_RS15570 3fb2549c0452e2100be49f3a0d2cffea 346 Pfam PF12849 PBP superfamily domain 27 307 7.6E-63 T 10-03-2017 IPR024370 PBP domain RG49_RS15570 3fb2549c0452e2100be49f3a0d2cffea 346 PIRSF PIRSF002756 1 338 1.9E-105 T 10-03-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 RG49_RS15270 7515c9987f7486e08255e9b7ead33c3c 355 SUPERFAMILY SSF51735 1 339 3.5E-96 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15270 7515c9987f7486e08255e9b7ead33c3c 355 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 341 1.1E-164 T 10-03-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 RG49_RS15270 7515c9987f7486e08255e9b7ead33c3c 355 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 327 2.7E-99 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15270 7515c9987f7486e08255e9b7ead33c3c 355 Gene3D G3DSA:3.40.50.720 1 192 1.2E-65 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS15270 7515c9987f7486e08255e9b7ead33c3c 355 Gene3D G3DSA:3.90.25.10 193 344 1.7E-56 T 10-03-2017 RG49_RS02820 3a3e229b9a51956bfd15416d5d0cb116 65 Pfam PF17073 Two-component-system connector protein 1 65 7.9E-48 T 10-03-2017 IPR031411 Two-component-system connector protein SafA RG49_RS13025 bf9857962d63f9a9d1c63b682285a5b6 141 SUPERFAMILY SSF46785 2 131 6.37E-34 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13025 bf9857962d63f9a9d1c63b682285a5b6 141 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 128 2.8E-36 T 10-03-2017 IPR000944 Transcription regulator Rrf2-type RG49_RS13025 bf9857962d63f9a9d1c63b682285a5b6 141 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 10-03-2017 IPR030489 Transcription regulator Rrf2-type, conserved site RG49_RS13025 bf9857962d63f9a9d1c63b682285a5b6 141 Gene3D G3DSA:1.10.10.10 2 133 3.8E-40 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13025 bf9857962d63f9a9d1c63b682285a5b6 141 Pfam PF02082 Transcriptional regulator 2 82 3.0E-24 T 10-03-2017 IPR000944 Transcription regulator Rrf2-type RG49_RS13025 bf9857962d63f9a9d1c63b682285a5b6 141 Hamap MF_01177 HTH-type transcriptional repressor NsrR [nsrR]. 1 141 45.136 T 10-03-2017 IPR023761 Transcriptional repressor HTH, NsrR GO:0045892 RG49_RS03490 acfbec2f06495833879b46452cddd638 879 Pfam PF11739 Dicarboxylate transport 657 858 4.3E-63 T 10-03-2017 IPR021730 Dicarboxylate transport RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 SUPERFAMILY SSF52794 186 281 1.33E-30 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 SUPERFAMILY SSF55804 21 169 1.1E-32 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 30 170 1.2E-32 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 Gene3D G3DSA:3.40.50.2300 182 282 9.3E-37 T 10-03-2017 RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 187 268 5.8E-23 T 10-03-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 72 88 - T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 Gene3D G3DSA:3.40.930.10 18 171 1.2E-41 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 296 641 1.6E-81 T 10-03-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 188 279 4.6E-16 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 Pfam PF02378 Phosphotransferase system, EIIC 313 565 1.5E-8 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS07400 974bd3e53a30264734a1ab5777d89ead 658 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 27 154 6.1E-39 T 10-03-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 RG49_RS23175 7ef397182a8bc6505c911d9ccddd495e 400 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 398 1.4E-146 T 10-03-2017 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 RG49_RS23175 7ef397182a8bc6505c911d9ccddd495e 400 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 10 82 3.7E-21 T 10-03-2017 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 RG49_RS23175 7ef397182a8bc6505c911d9ccddd495e 400 Pfam PF07670 Nucleoside recognition 92 189 5.2E-7 T 10-03-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 RG49_RS23175 7ef397182a8bc6505c911d9ccddd495e 400 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 193 398 8.5E-59 T 10-03-2017 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 RG49_RS09150 d3567050d33537b14171a7be74772179 394 Gene3D G3DSA:1.20.1250.20 3 188 1.1E-24 T 10-03-2017 RG49_RS09150 d3567050d33537b14171a7be74772179 394 Gene3D G3DSA:1.20.1250.20 191 383 4.0E-13 T 10-03-2017 RG49_RS09150 d3567050d33537b14171a7be74772179 394 Pfam PF07690 Major Facilitator Superfamily 8 327 3.3E-36 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS09150 d3567050d33537b14171a7be74772179 394 SUPERFAMILY SSF103473 3 383 3.66E-49 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS19525 817ca838d7c7d7bf73b65676bdc60323 834 SUPERFAMILY SSF141729 33 153 2.88E-21 T 10-03-2017 RG49_RS19525 817ca838d7c7d7bf73b65676bdc60323 834 Pfam PF13953 PapC C-terminal domain 759 811 7.6E-11 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS19525 817ca838d7c7d7bf73b65676bdc60323 834 Pfam PF13954 PapC N-terminal domain 35 177 5.0E-30 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS19525 817ca838d7c7d7bf73b65676bdc60323 834 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 309 319 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS19525 817ca838d7c7d7bf73b65676bdc60323 834 Pfam PF00577 Outer membrane usher protein 195 746 1.7E-192 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS03070 feae38921f9a3bb2bbe6499fe348d4f9 66 Pfam PF01609 Transposase DDE domain 4 65 1.1E-9 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS17930 ab6b123f2a23748a846ec37834317980 225 Pfam PF01478 Type IV leader peptidase family 82 189 7.4E-29 T 10-03-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 RG49_RS17930 ab6b123f2a23748a846ec37834317980 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 158 169 7.1E-26 T 10-03-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial RG49_RS17930 ab6b123f2a23748a846ec37834317980 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 147 157 7.1E-26 T 10-03-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial RG49_RS17930 ab6b123f2a23748a846ec37834317980 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 170 185 7.1E-26 T 10-03-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial RG49_RS17930 ab6b123f2a23748a846ec37834317980 225 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 90 107 7.1E-26 T 10-03-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial RG49_RS14415 82423f46160b9ea3f63b799b4179fdac 296 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 25 290 6.2E-107 T 10-03-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 RG49_RS14415 82423f46160b9ea3f63b799b4179fdac 296 Gene3D G3DSA:3.20.20.220 13 293 3.6E-109 T 10-03-2017 IPR029041 FAD-linked oxidoreductase-like RG49_RS14415 82423f46160b9ea3f63b799b4179fdac 296 SUPERFAMILY SSF51730 22 294 1.24E-97 T 10-03-2017 IPR029041 FAD-linked oxidoreductase-like RG49_RS14415 82423f46160b9ea3f63b799b4179fdac 296 Pfam PF02219 Methylenetetrahydrofolate reductase 16 291 1.3E-108 T 10-03-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 RG49_RS14910 6fef7098bf0d49adc0ce6c0e8a853640 175 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 10 144 1.3E-49 T 10-03-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 RG49_RS14910 6fef7098bf0d49adc0ce6c0e8a853640 175 SUPERFAMILY SSF52540 7 172 4.22E-23 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14910 6fef7098bf0d49adc0ce6c0e8a853640 175 Gene3D G3DSA:3.40.50.300 5 171 2.1E-60 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14910 6fef7098bf0d49adc0ce6c0e8a853640 175 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 10 169 3.7E-50 T 10-03-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 RG49_RS23310 34a5a931e23b5bfed3c6aab038ba34c8 387 TIGRFAM TIGR00998 8a0101: efflux pump membrane protein 14 338 4.9E-147 T 10-03-2017 IPR005694 Efflux pump membrane protein Emr GO:0006855|GO:0015238 RG49_RS23310 34a5a931e23b5bfed3c6aab038ba34c8 387 Gene3D G3DSA:2.40.50.100 57 87 1.6E-16 T 10-03-2017 RG49_RS23310 34a5a931e23b5bfed3c6aab038ba34c8 387 Gene3D G3DSA:2.40.50.100 208 241 1.6E-16 T 10-03-2017 RG49_RS23310 34a5a931e23b5bfed3c6aab038ba34c8 387 Pfam PF00529 HlyD membrane-fusion protein of T1SS 34 340 1.9E-16 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS23310 34a5a931e23b5bfed3c6aab038ba34c8 387 SUPERFAMILY SSF111369 187 260 1.7E-8 T 10-03-2017 RG49_RS23310 34a5a931e23b5bfed3c6aab038ba34c8 387 SUPERFAMILY SSF111369 105 154 1.7E-8 T 10-03-2017 RG49_RS23310 34a5a931e23b5bfed3c6aab038ba34c8 387 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 285 1.0E-13 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 Gene3D G3DSA:3.30.70.600 3 102 2.3E-42 T 10-03-2017 IPR027486 Ribosomal protein S10 domain RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 SUPERFAMILY SSF54999 5 101 1.02E-35 T 10-03-2017 IPR027486 Ribosomal protein S10 domain RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.898 T 10-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.5E-17 T 10-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.5E-17 T 10-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.5E-17 T 10-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 10-03-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 SMART SM01403 7 101 8.9E-55 T 10-03-2017 IPR027486 Ribosomal protein S10 domain RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-45 T 10-03-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS17995 9d6129626f9f807a8ce60eb3fa40b527 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.4E-34 T 10-03-2017 IPR027486 Ribosomal protein S10 domain RG49_RS12305 72f383200ad27510327283aeb23d52e5 410 SUPERFAMILY SSF103473 17 401 2.09E-46 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS12305 72f383200ad27510327283aeb23d52e5 410 Pfam PF07690 Major Facilitator Superfamily 23 354 7.5E-32 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS12305 72f383200ad27510327283aeb23d52e5 410 Gene3D G3DSA:1.20.1250.20 18 193 1.3E-23 T 10-03-2017 RG49_RS12305 72f383200ad27510327283aeb23d52e5 410 Gene3D G3DSA:1.20.1250.20 214 408 7.0E-5 T 10-03-2017 RG49_RS12305 72f383200ad27510327283aeb23d52e5 410 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 85 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS17500 7701cee638126aa337a3aabdb089aac5 227 SUPERFAMILY SSF53271 45 225 2.1E-37 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS17500 7701cee638126aa337a3aabdb089aac5 227 TIGRFAM TIGR00201 comF: comF family protein 23 225 5.8E-83 T 10-03-2017 IPR005222 Competence protein ComF RG49_RS17500 7701cee638126aa337a3aabdb089aac5 227 Pfam PF00156 Phosphoribosyl transferase domain 173 224 5.5E-8 T 10-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 RG49_RS17500 7701cee638126aa337a3aabdb089aac5 227 Gene3D G3DSA:3.40.50.2020 50 226 2.0E-26 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS04680 baa8b47e694a5018f0ec81cde9229747 84 Pfam PF04226 Transglycosylase associated protein 34 83 6.8E-14 T 10-03-2017 IPR007341 Transglycosylase-associated protein GO:0016021 RG49_RS09925 84e29e7b0806df3a96cabaf970bdacd4 403 SUPERFAMILY SSF103473 8 395 1.05E-66 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS09925 84e29e7b0806df3a96cabaf970bdacd4 403 Pfam PF07690 Major Facilitator Superfamily 19 300 2.3E-34 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS09925 84e29e7b0806df3a96cabaf970bdacd4 403 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS09925 84e29e7b0806df3a96cabaf970bdacd4 403 ProSitePatterns PS00217 Sugar transport proteins signature 2. 110 135 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS09925 84e29e7b0806df3a96cabaf970bdacd4 403 Gene3D G3DSA:1.20.1250.20 216 393 5.7E-18 T 10-03-2017 RG49_RS09925 84e29e7b0806df3a96cabaf970bdacd4 403 Gene3D G3DSA:1.20.1250.20 14 190 7.5E-27 T 10-03-2017 RG49_RS03785 415ee6b0118dd8fe5eae1c9238df588f 69 Pfam PF06688 Protein of unknown function (DUF1187) 2 62 8.8E-39 T 10-03-2017 IPR009572 Protein of unknown function DUF1187 RG49_RS03785 415ee6b0118dd8fe5eae1c9238df588f 69 ProDom PD055514 YDAC STY2075 PLASMID YHEB ECS1931 1 62 2.0E-29 T 10-03-2017 IPR009572 Protein of unknown function DUF1187 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 Gene3D G3DSA:1.10.10.10 4 59 6.2E-8 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 Gene3D G3DSA:3.40.50.1360 78 215 1.8E-11 T 10-03-2017 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 SMART SM00420 6 58 1.9E-25 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 SMART SM01134 74 234 4.3E-58 T 10-03-2017 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 SUPERFAMILY SSF100950 76 234 1.26E-30 T 10-03-2017 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 SUPERFAMILY SSF46785 4 71 1.78E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 Pfam PF00455 DeoR C terminal sensor domain 77 233 1.6E-48 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.8E-8 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.8E-8 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS01135 e3c8c761621f1579d3966119cd3a113e 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 2.6E-17 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 SUPERFAMILY SSF52540 276 525 1.01E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 Gene3D G3DSA:3.40.50.300 4 258 6.4E-72 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 Gene3D G3DSA:3.40.50.300 275 526 3.4E-77 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 SMART SM00382 34 306 3.2E-16 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 SMART SM00382 311 502 1.2E-18 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 SUPERFAMILY SSF52540 5 256 8.59E-65 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 Pfam PF00005 ABC transporter 26 184 3.1E-27 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 Pfam PF00005 ABC transporter 302 454 2.0E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 505 526 0.37 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS24250 016d161b172c0e84f2e421d3d71ef91e 529 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 265 1.7E-4 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS09125 bab745c09ee80710ad1f5407e19f9037 439 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 415 1.5E-165 T 10-03-2017 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 RG49_RS09125 bab745c09ee80710ad1f5407e19f9037 439 Pfam PF05525 Branched-chain amino acid transport protein 8 429 9.2E-161 T 10-03-2017 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 SUPERFAMILY SSF52540 71 291 1.76E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 SMART SM00382 94 248 3.3E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 Pfam PF13481 AAA domain 88 225 4.6E-15 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 PRINTS PR01874 DNA repair protein radA signature 127 144 1.9E-93 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 PRINTS PR01874 DNA repair protein radA signature 216 244 1.9E-93 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 PRINTS PR01874 DNA repair protein radA signature 325 348 1.9E-93 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 PRINTS PR01874 DNA repair protein radA signature 177 201 1.9E-93 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 PRINTS PR01874 DNA repair protein radA signature 11 35 1.9E-93 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 PRINTS PR01874 DNA repair protein radA signature 86 114 1.9E-93 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 PRINTS PR01874 DNA repair protein radA signature 251 277 1.9E-93 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 SUPERFAMILY SSF54211 258 272 1.33E-41 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 SUPERFAMILY SSF54211 306 457 1.33E-41 T 10-03-2017 IPR020568 Ribosomal protein S5 domain 2-type fold RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 Gene3D G3DSA:3.30.230.10 288 456 1.5E-38 T 10-03-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 Pfam PF13541 Subunit ChlI of Mg-chelatase 348 433 1.7E-9 T 10-03-2017 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 454 5.4E-240 T 10-03-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 Hamap MF_01498 DNA repair protein RadA [radA]. 22 458 43.368 T 10-03-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 RG49_RS11970 856a0abd3d7df46f2348dfd5e2ec41c5 460 Gene3D G3DSA:3.40.50.300 62 280 3.3E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18510 6d009ab9d5f35a3f58241b7a35cf21ac 229 Gene3D G3DSA:3.20.20.70 9 226 9.7E-92 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS18510 6d009ab9d5f35a3f58241b7a35cf21ac 229 SUPERFAMILY SSF51366 14 224 1.77E-56 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS18510 6d009ab9d5f35a3f58241b7a35cf21ac 229 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 11 225 38.055 T 10-03-2017 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 RG49_RS18510 6d009ab9d5f35a3f58241b7a35cf21ac 229 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 35 226 1.2E-92 T 10-03-2017 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 RG49_RS22700 089b02b48f3fa3909d3585ecae01c91f 137 ProDom PD021295 MATURATION HYDROGENLYASE FORMATE HYCH LYASE HYCE PROCESSING OXIDOREDUCTASE J COMPONENT 6 136 2.0E-73 T 10-03-2017 IPR010005 Formate hydrogenlyase maturation HycH RG49_RS22700 089b02b48f3fa3909d3585ecae01c91f 137 Pfam PF07450 Formate hydrogenlyase maturation protein HycH 7 135 5.7E-51 T 10-03-2017 IPR010005 Formate hydrogenlyase maturation HycH RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 Pfam PF12848 ABC transporter 224 309 5.2E-21 T 10-03-2017 IPR032781 ABC-transporter extension domain RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 Pfam PF00005 ABC transporter 18 184 1.9E-19 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 Pfam PF00005 ABC transporter 336 467 4.9E-24 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 SUPERFAMILY SSF52540 6 237 6.73E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 Gene3D G3DSA:3.40.50.300 318 528 1.1E-45 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 Gene3D G3DSA:3.40.50.300 132 280 5.1E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 Gene3D G3DSA:3.40.50.300 5 100 5.1E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 SMART SM00382 26 228 7.1E-10 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 SMART SM00382 344 521 1.4E-11 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06905 a4a654b4e89c024c3efdd151385ebf54 530 SUPERFAMILY SSF52540 298 523 1.56E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03675 0b87c53870e928bf951a71d135ae4049 425 Pfam PF10011 Predicted membrane protein (DUF2254) 15 370 2.4E-93 T 10-03-2017 IPR018723 Protein of unknown function DUF2254, membrane RG49_RS01065 ba3043f2e2914b147276f033cc5c8740 427 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 423 42.712 T 10-03-2017 IPR006698 Uncharacterised protein family UPF0229 RG49_RS01065 ba3043f2e2914b147276f033cc5c8740 427 Pfam PF04285 Protein of unknown function (DUF444) 4 421 1.5E-186 T 10-03-2017 IPR006698 Uncharacterised protein family UPF0229 RG49_RS20085 942656c075cbe0d7989ebcf0cc018006 239 Pfam PF02390 Putative methyltransferase 64 233 5.8E-62 T 10-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 RG49_RS20085 942656c075cbe0d7989ebcf0cc018006 239 Gene3D G3DSA:3.40.50.150 53 193 2.5E-14 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS20085 942656c075cbe0d7989ebcf0cc018006 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 24 238 30.392 T 10-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 RG49_RS20085 942656c075cbe0d7989ebcf0cc018006 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 49 238 8.1E-76 T 10-03-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 RG49_RS20085 942656c075cbe0d7989ebcf0cc018006 239 SUPERFAMILY SSF53335 18 237 6.65E-38 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 SUPERFAMILY SSF51338 2 49 8.64E-9 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 SUPERFAMILY SSF51338 345 378 8.64E-9 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 2 378 3.2E-167 T 10-03-2017 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399 RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 Pfam PF07969 Amidohydrolase family 227 378 5.1E-12 T 10-03-2017 IPR013108 Amidohydrolase 3 RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 SUPERFAMILY SSF51556 50 345 2.13E-22 T 10-03-2017 IPR032466 Metal-dependent hydrolase RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 Gene3D G3DSA:3.20.20.140 213 376 3.1E-9 T 10-03-2017 RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 PIRSF PIRSF038971 1 378 2.5E-154 T 10-03-2017 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399 RG49_RS13505 73dedb9a6a38d76f551b7f99b35ae1bd 378 Gene3D G3DSA:2.30.40.10 1 91 1.0E-8 T 10-03-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 RG49_RS21930 977ce8806a2aa645622b342adb4254db 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 160 73.317 T 10-03-2017 IPR000037 SsrA-binding protein GO:0003723 RG49_RS21930 977ce8806a2aa645622b342adb4254db 160 Gene3D G3DSA:2.40.280.10 13 133 1.4E-49 T 10-03-2017 IPR023620 Small protein B RG49_RS21930 977ce8806a2aa645622b342adb4254db 160 SUPERFAMILY SSF74982 8 138 7.19E-51 T 10-03-2017 IPR023620 Small protein B RG49_RS21930 977ce8806a2aa645622b342adb4254db 160 ProSitePatterns PS01317 SsrA-binding protein. 32 44 - T 10-03-2017 IPR020081 SsrA-binding protein, conserved site RG49_RS21930 977ce8806a2aa645622b342adb4254db 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 138 1.0E-69 T 10-03-2017 IPR000037 SsrA-binding protein GO:0003723 RG49_RS21930 977ce8806a2aa645622b342adb4254db 160 Pfam PF01668 SmpB protein 13 75 3.9E-28 T 10-03-2017 IPR000037 SsrA-binding protein GO:0003723 RG49_RS21930 977ce8806a2aa645622b342adb4254db 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 14 156 1.7E-54 T 10-03-2017 IPR000037 SsrA-binding protein GO:0003723 RG49_RS18070 98f615537815942b22a86925403a8f47 130 SUPERFAMILY SSF56047 5 129 4.97E-46 T 10-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18070 98f615537815942b22a86925403a8f47 130 Gene3D G3DSA:3.30.1490.10 74 129 4.2E-28 T 10-03-2017 RG49_RS18070 98f615537815942b22a86925403a8f47 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 10-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18070 98f615537815942b22a86925403a8f47 130 Gene3D G3DSA:3.30.1370.30 2 72 2.3E-28 T 10-03-2017 RG49_RS18070 98f615537815942b22a86925403a8f47 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 31.942 T 10-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS18070 98f615537815942b22a86925403a8f47 130 Pfam PF00410 Ribosomal protein S8 5 129 4.8E-49 T 10-03-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 RG49_RS01685 84aa1338b6e7ce221b8ef618b21c75b8 261 Pfam PF01292 Prokaryotic cytochrome b561 69 257 7.6E-29 T 10-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 RG49_RS01685 84aa1338b6e7ce221b8ef618b21c75b8 261 SUPERFAMILY SSF81342 62 259 4.0E-25 T 10-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 RG49_RS01685 84aa1338b6e7ce221b8ef618b21c75b8 261 Gene3D G3DSA:1.20.950.20 62 258 3.2E-36 T 10-03-2017 RG49_RS03655 e9073d7e65cfdf2a956d6f3ee97ea13c 70 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 43 8.0E-15 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS03655 e9073d7e65cfdf2a956d6f3ee97ea13c 70 PRINTS PR00281 Hok/Gef cell toxic protein family signature 45 67 8.0E-15 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS03655 e9073d7e65cfdf2a956d6f3ee97ea13c 70 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 30 49 - T 10-03-2017 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 RG49_RS03655 e9073d7e65cfdf2a956d6f3ee97ea13c 70 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 31 67 1.0E-5 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS03655 e9073d7e65cfdf2a956d6f3ee97ea13c 70 Pfam PF01848 Hok/gef family 25 66 1.1E-20 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS22190 1c27f669ed8650035a7406302163535c 159 PIRSF PIRSF004923 1 150 3.5E-44 T 10-03-2017 IPR026268 Protein RseC RG49_RS22190 1c27f669ed8650035a7406302163535c 159 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 139 1.5E-32 T 10-03-2017 IPR007359 Positive regulator of sigma(E), RseC/MucC RG49_RS10195 245145e84cb671d7ab7f450f4e1df83a 266 Gene3D G3DSA:3.90.1340.10 103 160 9.4E-15 T 10-03-2017 IPR011083 Phage tail collar domain RG49_RS10195 245145e84cb671d7ab7f450f4e1df83a 266 SUPERFAMILY SSF88874 97 265 5.89E-43 T 10-03-2017 RG49_RS10195 245145e84cb671d7ab7f450f4e1df83a 266 Pfam PF07484 Phage Tail Collar Domain 108 155 1.9E-14 T 10-03-2017 IPR011083 Phage tail collar domain RG49_RS23870 e91610c3c11c3cb4105ed928db5f1743 267 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 19 244 5.3E-69 T 10-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 RG49_RS23870 e91610c3c11c3cb4105ed928db5f1743 267 Gene3D G3DSA:3.20.20.60 5 255 2.7E-81 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS23870 e91610c3c11c3cb4105ed928db5f1743 267 Hamap MF_01290 2-keto-3-deoxy-L-rhamnonate aldolase [rhmA]. 1 267 75.029 T 10-03-2017 IPR023593 2-keto-3-deoxy-L-rhamnonate aldolase GO:0016832 KEGG: 00051+4.1.2.53|MetaCyc: PWY-6713 RG49_RS23870 e91610c3c11c3cb4105ed928db5f1743 267 SUPERFAMILY SSF51621 5 255 9.74E-83 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS17295 b4b9ddc62b83e0c01a9bb78d44ce39f4 425 Pfam PF11862 Domain of unknown function (DUF3382) 6 103 1.0E-24 T 10-03-2017 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal RG49_RS17295 b4b9ddc62b83e0c01a9bb78d44ce39f4 425 Pfam PF02653 Branched-chain amino acid transport system / permease component 112 398 1.9E-60 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS21195 13edd82a09e72f9dd5eb21381fd0d0fd 469 ProSitePatterns PS00217 Sugar transport proteins signature 2. 140 165 - T 10-03-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 RG49_RS21195 13edd82a09e72f9dd5eb21381fd0d0fd 469 Pfam PF00083 Sugar (and other) transporter 53 453 7.0E-51 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS21195 13edd82a09e72f9dd5eb21381fd0d0fd 469 Gene3D G3DSA:1.20.1250.20 270 449 9.3E-15 T 10-03-2017 RG49_RS21195 13edd82a09e72f9dd5eb21381fd0d0fd 469 SUPERFAMILY SSF103473 32 452 1.27E-68 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS21195 13edd82a09e72f9dd5eb21381fd0d0fd 469 Gene3D G3DSA:1.20.1250.20 46 225 1.6E-27 T 10-03-2017 RG49_RS21735 4c50622d1f0d6d6c99358eb8ce0a5eb9 114 SUPERFAMILY SSF159894 1 111 2.25E-59 T 10-03-2017 RG49_RS21735 4c50622d1f0d6d6c99358eb8ce0a5eb9 114 Pfam PF09400 Protein of unknown function (DUF2002) 1 110 4.8E-61 T 10-03-2017 IPR018994 Protein of unknown function DUF2002 RG49_RS08805 12c7241ea3ff19fca3246f734db77c39 72 SUPERFAMILY SSF68989 2 72 9.94E-32 T 10-03-2017 IPR007985 Haemolysin expression modulating, HHA RG49_RS08805 12c7241ea3ff19fca3246f734db77c39 72 Gene3D G3DSA:1.20.1280.40 6 72 1.4E-37 T 10-03-2017 IPR007985 Haemolysin expression modulating, HHA RG49_RS08805 12c7241ea3ff19fca3246f734db77c39 72 Pfam PF05321 Haemolysin expression modulating protein 13 69 1.4E-33 T 10-03-2017 IPR007985 Haemolysin expression modulating, HHA RG49_RS10480 51d7ac9b20c7c709cc5e1ee377955b92 414 SUPERFAMILY SSF53474 46 413 3.39E-55 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS10480 51d7ac9b20c7c709cc5e1ee377955b92 414 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 1 414 1.7E-222 T 10-03-2017 IPR010520 UPF0255 family RG49_RS10480 51d7ac9b20c7c709cc5e1ee377955b92 414 Hamap MF_01063 Esterase FrsA [frsA]. 1 414 65.18 T 10-03-2017 IPR010520 UPF0255 family RG49_RS10480 51d7ac9b20c7c709cc5e1ee377955b92 414 Gene3D G3DSA:3.40.50.1820 346 412 1.5E-27 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS10480 51d7ac9b20c7c709cc5e1ee377955b92 414 Gene3D G3DSA:3.40.50.1820 157 301 1.5E-27 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS00205 6b83302f620c4a9aedf46505490d2c81 457 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 162 373 2.1E-70 T 10-03-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS00205 6b83302f620c4a9aedf46505490d2c81 457 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 364 373 - T 10-03-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS00205 6b83302f620c4a9aedf46505490d2c81 457 SMART SM00382 174 357 7.6E-8 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS00205 6b83302f620c4a9aedf46505490d2c81 457 SUPERFAMILY SSF52540 109 379 1.69E-92 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00205 6b83302f620c4a9aedf46505490d2c81 457 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 29 451 6.9E-196 T 10-03-2017 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS00205 6b83302f620c4a9aedf46505490d2c81 457 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 6 453 2.7E-201 T 10-03-2017 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 RG49_RS00205 6b83302f620c4a9aedf46505490d2c81 457 Gene3D G3DSA:3.40.50.300 138 421 3.1E-89 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 SMART SM00420 8 57 7.0E-15 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 10-03-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 SUPERFAMILY SSF100950 74 236 7.22E-31 T 10-03-2017 RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 Gene3D G3DSA:1.10.10.10 3 43 1.1E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 Gene3D G3DSA:3.40.50.1360 77 215 2.2E-9 T 10-03-2017 RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 SMART SM01134 73 234 1.5E-56 T 10-03-2017 RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 Pfam PF00455 DeoR C terminal sensor domain 76 232 1.5E-45 T 10-03-2017 IPR014036 DeoR C-terminal sensor domain RG49_RS06805 8ee9773f9e113ce236aaaf69eec21e0d 252 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 9.7E-15 T 10-03-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 RG49_RS01465 cc7473d584bb508c165ca41b53c0bea2 326 Pfam PF01032 FecCD transport family 22 323 7.4E-87 T 10-03-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 RG49_RS01465 cc7473d584bb508c165ca41b53c0bea2 326 SUPERFAMILY SSF81345 7 323 1.11E-84 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS01465 cc7473d584bb508c165ca41b53c0bea2 326 Hamap MF_01004 Vitamin B12 import system permease protein BtuC [btuC]. 1 326 32.405 T 10-03-2017 IPR023691 ABC transporter, vitamin B12 import, permease protein BtuC GO:0015889|GO:0016020 RG49_RS01465 cc7473d584bb508c165ca41b53c0bea2 326 Gene3D G3DSA:1.10.3470.10 6 324 2.7E-102 T 10-03-2017 IPR029022 ABC transporter, BtuC-like RG49_RS10570 327c877d6f5c7e3c5044d7e2ffeb1d4e 192 Pfam PF13580 SIS domain 12 146 2.6E-32 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS10570 327c877d6f5c7e3c5044d7e2ffeb1d4e 192 Gene3D G3DSA:3.40.50.10490 1 190 6.7E-64 T 10-03-2017 RG49_RS10570 327c877d6f5c7e3c5044d7e2ffeb1d4e 192 SUPERFAMILY SSF53697 1 189 2.6E-52 T 10-03-2017 RG49_RS10570 327c877d6f5c7e3c5044d7e2ffeb1d4e 192 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 38.958 T 10-03-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 RG49_RS10570 327c877d6f5c7e3c5044d7e2ffeb1d4e 192 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 35 187 1.4E-84 T 10-03-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 RG49_RS05105 6d811a959a23ed1a3377425992e348e2 180 SUPERFAMILY SSF53474 2 176 4.47E-8 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS05105 6d811a959a23ed1a3377425992e348e2 180 Hamap MF_01047 UPF0227 protein YcfP [ycfP]. 1 178 56.44 T 10-03-2017 IPR022987 Uncharacterised protein family UPF0227 RG49_RS05105 6d811a959a23ed1a3377425992e348e2 180 Gene3D G3DSA:3.40.50.1820 2 77 4.9E-5 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS05105 6d811a959a23ed1a3377425992e348e2 180 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 177 6.8E-72 T 10-03-2017 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA RG49_RS01810 260d44bed7fa8dcab1d896019c54f35a 298 Pfam PF00248 Aldo/keto reductase family 18 291 1.0E-57 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS01810 260d44bed7fa8dcab1d896019c54f35a 298 SUPERFAMILY SSF51430 4 295 1.06E-71 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS01810 260d44bed7fa8dcab1d896019c54f35a 298 Gene3D G3DSA:3.20.20.100 2 292 6.3E-65 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS01810 260d44bed7fa8dcab1d896019c54f35a 298 PRINTS PR00069 Aldo-keto reductase signature 112 130 6.0E-6 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS01810 260d44bed7fa8dcab1d896019c54f35a 298 PRINTS PR00069 Aldo-keto reductase signature 143 160 6.0E-6 T 10-03-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 RG49_RS15970 631fc3693468fa20b776944815bc5784 307 SUPERFAMILY SSF103481 191 296 2.48E-13 T 10-03-2017 RG49_RS15970 631fc3693468fa20b776944815bc5784 307 Pfam PF00892 EamA-like transporter family 6 145 7.4E-21 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS15970 631fc3693468fa20b776944815bc5784 307 Pfam PF00892 EamA-like transporter family 158 290 1.5E-21 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS15970 631fc3693468fa20b776944815bc5784 307 SUPERFAMILY SSF103481 43 148 9.68E-7 T 10-03-2017 RG49_RS15970 631fc3693468fa20b776944815bc5784 307 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 18 287 2.6E-78 T 10-03-2017 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 SUPERFAMILY SSF53067 85 205 4.53E-27 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 SUPERFAMILY SSF53067 2 44 4.53E-27 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 213 226 - T 10-03-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 Gene3D G3DSA:3.90.640.10 306 364 4.1E-4 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 SUPERFAMILY SSF53067 208 276 2.07E-30 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 SUPERFAMILY SSF53067 328 447 2.07E-30 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 Gene3D G3DSA:3.30.420.40 85 217 2.0E-30 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 Gene3D G3DSA:3.30.420.40 2 43 2.0E-30 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 Pfam PF00012 Hsp70 protein 3 228 1.5E-14 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 Pfam PF00012 Hsp70 protein 330 422 3.4E-7 T 10-03-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 Gene3D G3DSA:3.30.420.40 374 433 2.7E-14 T 10-03-2017 RG49_RS24830 a517e6b99f48c6674b37664fdbac6dd4 450 Gene3D G3DSA:3.30.420.40 218 241 2.7E-14 T 10-03-2017 RG49_RS18245 ad63e3236acfbfa00af77ac3b4b38c45 252 Gene3D G3DSA:3.40.50.300 11 248 1.2E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18245 ad63e3236acfbfa00af77ac3b4b38c45 252 PIRSF PIRSF039085 9 252 1.4E-107 T 10-03-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 RG49_RS18245 ad63e3236acfbfa00af77ac3b4b38c45 252 SUPERFAMILY SSF52540 12 246 1.1E-80 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18245 ad63e3236acfbfa00af77ac3b4b38c45 252 SMART SM00382 37 224 1.6E-17 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS18245 ad63e3236acfbfa00af77ac3b4b38c45 252 Pfam PF00005 ABC transporter 28 176 1.4E-37 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS18245 ad63e3236acfbfa00af77ac3b4b38c45 252 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS08960 2392f87dc99df6eb16be9adf8acd782b 226 Pfam PF08139 Prokaryotic membrane lipoprotein lipid attachment site 2 54 3.0E-17 T 10-03-2017 IPR012640 Membrane lipoprotein, lipid attachment site RG49_RS08960 2392f87dc99df6eb16be9adf8acd782b 226 Pfam PF03923 Uncharacterized lipoprotein 63 222 4.8E-53 T 10-03-2017 IPR005619 Uncharacterised protein family, YajG RG49_RS11730 9b645bb4da5c24a326dc2063b5c3faf4 149 Gene3D G3DSA:3.10.50.40 130 145 4.7E-20 T 10-03-2017 RG49_RS11730 9b645bb4da5c24a326dc2063b5c3faf4 149 Gene3D G3DSA:3.10.50.40 3 80 4.7E-20 T 10-03-2017 RG49_RS11730 9b645bb4da5c24a326dc2063b5c3faf4 149 SUPERFAMILY SSF54534 5 143 7.66E-37 T 10-03-2017 RG49_RS11730 9b645bb4da5c24a326dc2063b5c3faf4 149 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 5 141 2.2E-15 T 10-03-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 RG49_RS12200 937c936d0310cae58022ef098a533dc4 283 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 279 9.4E-89 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS12200 937c936d0310cae58022ef098a533dc4 283 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 281 3.1E-166 T 10-03-2017 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpaD-Fe KEGG: 00350+1.13.11.15 RG49_RS12200 937c936d0310cae58022ef098a533dc4 283 SUPERFAMILY SSF53213 12 279 1.28E-52 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS12200 937c936d0310cae58022ef098a533dc4 283 Gene3D G3DSA:3.40.830.10 5 270 4.5E-30 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS07445 753b0fd70db6b7058990018f6ede9e17 115 PIRSF PIRSF000169 1 115 3.9E-42 T 10-03-2017 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 RG49_RS07445 753b0fd70db6b7058990018f6ede9e17 115 Gene3D G3DSA:1.20.1300.10 1 115 4.7E-40 T 10-03-2017 RG49_RS07445 753b0fd70db6b7058990018f6ede9e17 115 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 10 113 3.2E-37 T 10-03-2017 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 RG49_RS07445 753b0fd70db6b7058990018f6ede9e17 115 SUPERFAMILY SSF81343 5 115 1.96E-31 T 10-03-2017 RG49_RS07445 753b0fd70db6b7058990018f6ede9e17 115 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 105 2.0E-6 T 10-03-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 RG49_RS10825 28a7814aeb6b097d83e34aff5982e20b 271 Gene3D G3DSA:3.40.190.10 30 162 2.9E-61 T 10-03-2017 RG49_RS10825 28a7814aeb6b097d83e34aff5982e20b 271 PIRSF PIRSF002854 1 271 6.8E-109 T 10-03-2017 IPR004872 Lipoprotein NlpA family RG49_RS10825 28a7814aeb6b097d83e34aff5982e20b 271 SUPERFAMILY SSF53850 33 271 5.31E-85 T 10-03-2017 RG49_RS10825 28a7814aeb6b097d83e34aff5982e20b 271 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 14 271 4.5E-153 T 10-03-2017 IPR004872 Lipoprotein NlpA family RG49_RS10825 28a7814aeb6b097d83e34aff5982e20b 271 Pfam PF03180 NLPA lipoprotein 33 271 4.1E-101 T 10-03-2017 IPR004872 Lipoprotein NlpA family RG49_RS19455 a6d3f91959c49091da24c96ae2e9597f 273 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 272 18.775 T 10-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 RG49_RS19455 a6d3f91959c49091da24c96ae2e9597f 273 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 265 3.2E-110 T 10-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 RG49_RS19455 a6d3f91959c49091da24c96ae2e9597f 273 Pfam PF02673 Bacitracin resistance protein BacA 10 266 1.8E-83 T 10-03-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 PIRSF PIRSF006728 1 384 1.1E-114 T 10-03-2017 IPR008135 Competence-induced protein CinA RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 SUPERFAMILY SSF142433 249 378 2.35E-5 T 10-03-2017 IPR008136 CinA, C-terminal RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 399 1.1E-193 T 10-03-2017 IPR008135 Competence-induced protein CinA RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 400 119.246 T 10-03-2017 IPR008135 Competence-induced protein CinA RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 Gene3D G3DSA:3.40.980.10 2 202 1.6E-28 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 SMART SM00852 5 172 2.1E-35 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 SUPERFAMILY SSF53218 2 204 1.44E-35 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 167 2.1E-38 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS23850 b4f20822833265e17d526ccda1e3cb4f 400 Pfam PF00994 Probable molybdopterin binding domain 6 170 5.0E-31 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS02480 d85310ee40a9bef231c18ffff24434bf 191 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 72 191 6.0E-40 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS19295 29c05b8702cd93fa00920db899d0db99 104 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 20 92 9.9E-22 T 10-03-2017 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 RG49_RS06225 060a51c91c15fb6764d5ea2d7f7ffcc4 246 Pfam PF13353 4Fe-4S single cluster domain 16 141 5.9E-18 T 10-03-2017 RG49_RS06225 060a51c91c15fb6764d5ea2d7f7ffcc4 246 Gene3D G3DSA:3.80.30.10 69 245 3.5E-71 T 10-03-2017 RG49_RS06225 060a51c91c15fb6764d5ea2d7f7ffcc4 246 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 239 4.8E-108 T 10-03-2017 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 RG49_RS06225 060a51c91c15fb6764d5ea2d7f7ffcc4 246 Pfam PF04055 Radical SAM superfamily 24 178 1.4E-31 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS06225 060a51c91c15fb6764d5ea2d7f7ffcc4 246 SUPERFAMILY SSF102114 23 217 2.55E-24 T 10-03-2017 RG49_RS06225 060a51c91c15fb6764d5ea2d7f7ffcc4 246 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 10-03-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 RG49_RS23390 7f14a0bca65b755ba64567fd4e919b7a 881 SUPERFAMILY SSF141729 32 154 1.24E-28 T 10-03-2017 RG49_RS23390 7f14a0bca65b755ba64567fd4e919b7a 881 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 321 331 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS23390 7f14a0bca65b755ba64567fd4e919b7a 881 Pfam PF13954 PapC N-terminal domain 34 179 3.7E-35 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS23390 7f14a0bca65b755ba64567fd4e919b7a 881 Pfam PF00577 Outer membrane usher protein 197 759 4.9E-203 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS23390 7f14a0bca65b755ba64567fd4e919b7a 881 Pfam PF13953 PapC C-terminal domain 770 827 3.5E-13 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS02395 be957265c2f956f4852a711504c17cef 502 Pfam PF05136 Phage portal protein, lambda family 35 372 3.0E-80 T 10-03-2017 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 RG49_RS02395 be957265c2f956f4852a711504c17cef 502 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 31 476 1.1E-137 T 10-03-2017 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 RG49_RS19105 671655356ba828e694f2c15b691c0912 395 SUPERFAMILY SSF141571 152 201 3.4E-6 T 10-03-2017 RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 SMART SM01011 4 139 5.2E-59 T 10-03-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 Pfam PF00557 Metallopeptidase family M24 185 414 1.5E-64 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 SUPERFAMILY SSF55920 178 436 2.36E-88 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 Gene3D G3DSA:3.40.350.10 4 181 8.6E-56 T 10-03-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 Pfam PF05195 Aminopeptidase P, N-terminal domain 9 129 1.0E-36 T 10-03-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 351 363 - T 10-03-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 PRINTS PR00599 Methionine aminopeptidase-1 signature 373 385 1.1E-5 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 PRINTS PR00599 Methionine aminopeptidase-1 signature 256 272 1.1E-5 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 Gene3D G3DSA:3.90.230.10 182 437 1.3E-88 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS20365 a80c6a4be269c78db05dad261c7d3d10 441 SUPERFAMILY SSF53092 4 177 6.02E-54 T 10-03-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal RG49_RS23560 12cdbbf29c934869d738de98dec2670d 297 Gene3D G3DSA:3.90.25.10 199 248 1.8E-5 T 10-03-2017 RG49_RS23560 12cdbbf29c934869d738de98dec2670d 297 SUPERFAMILY SSF51735 1 296 9.29E-47 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS23560 12cdbbf29c934869d738de98dec2670d 297 Pfam PF08338 Domain of unknown function (DUF1731) 249 295 4.1E-19 T 10-03-2017 IPR013549 Domain of unknown function DUF1731 RG49_RS23560 12cdbbf29c934869d738de98dec2670d 297 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 292 4.2E-110 T 10-03-2017 IPR010099 Epimerase family protein SDR39U1 RG49_RS23560 12cdbbf29c934869d738de98dec2670d 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 214 7.1E-23 T 10-03-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 RG49_RS23560 12cdbbf29c934869d738de98dec2670d 297 Gene3D G3DSA:3.40.50.720 1 198 7.8E-25 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS22505 7e34e8464154a27d30ff2bd9940fd001 206 Pfam PF09976 Tetratricopeptide repeat-like domain 15 205 1.0E-55 T 10-03-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 RG49_RS22505 7e34e8464154a27d30ff2bd9940fd001 206 PIRSF PIRSF006170 1 206 6.8E-60 T 10-03-2017 IPR026039 Uncharacterised protein family UPF0070 RG49_RS22505 7e34e8464154a27d30ff2bd9940fd001 206 Gene3D G3DSA:1.25.40.10 53 186 5.1E-5 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS22505 7e34e8464154a27d30ff2bd9940fd001 206 SUPERFAMILY SSF48452 88 186 7.59E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS19800 d3def59d2540f906d8b31bd384435782 162 ProDom PD008308 HUPJ HYDROGENASE EXPRESSION/FORMATION HYDROGENASE-2 HYBE COMPONENT OPERON ELECTRON METAL-BINDING IRON 16 157 3.0E-67 T 10-03-2017 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE RG49_RS19800 d3def59d2540f906d8b31bd384435782 162 Pfam PF11939 Protein of unknown function (DUF3457) 12 155 1.7E-42 T 10-03-2017 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE RG49_RS19800 d3def59d2540f906d8b31bd384435782 162 TIGRFAM TIGR03993 hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family 16 153 7.7E-48 T 10-03-2017 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 SUPERFAMILY SSF52172 1 125 7.54E-27 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 SMART SM00421 135 192 1.7E-25 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 SUPERFAMILY SSF46894 130 193 4.42E-20 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 Pfam PF00072 Response regulator receiver domain 4 112 2.4E-24 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 1.8E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 1.8E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 1.8E-13 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 190 2.4E-23 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 Gene3D G3DSA:3.40.50.2300 1 141 2.1E-31 T 10-03-2017 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 ProSitePatterns PS00622 LuxR-type HTH domain signature. 152 179 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 Gene3D G3DSA:1.10.10.10 142 192 1.9E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15905 4aef5d5ffaa64bb81138a848c65b368b 196 SMART SM00448 2 112 4.8E-27 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS14340 9b0240ae4e2576655c91f9f764c43be2 577 Pfam PF08019 Domain of unknown function (DUF1705) 56 206 5.6E-5 T 10-03-2017 IPR012549 Domain of unknown function DUF1705 GO:0016021 RG49_RS14340 9b0240ae4e2576655c91f9f764c43be2 577 SUPERFAMILY SSF53649 235 554 3.18E-31 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS14340 9b0240ae4e2576655c91f9f764c43be2 577 Gene3D G3DSA:3.40.720.10 240 535 9.1E-14 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS14340 9b0240ae4e2576655c91f9f764c43be2 577 Pfam PF00884 Sulfatase 238 529 3.8E-46 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS18635 5b94fca7e3e7cf91dbf3e34e22a4c66b 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS18635 5b94fca7e3e7cf91dbf3e34e22a4c66b 241 SMART SM00382 28 213 5.4E-10 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS18635 5b94fca7e3e7cf91dbf3e34e22a4c66b 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 1.6E-7 T 10-03-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal RG49_RS18635 5b94fca7e3e7cf91dbf3e34e22a4c66b 241 Pfam PF00005 ABC transporter 20 166 7.1E-34 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS18635 5b94fca7e3e7cf91dbf3e34e22a4c66b 241 Gene3D G3DSA:3.40.50.300 3 234 3.7E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18635 5b94fca7e3e7cf91dbf3e34e22a4c66b 241 SUPERFAMILY SSF52540 4 236 1.13E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS18635 5b94fca7e3e7cf91dbf3e34e22a4c66b 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 3 241 1.9E-120 T 10-03-2017 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 40 472 8.6E-168 T 10-03-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 SUPERFAMILY SSF50494 7 59 1.97E-64 T 10-03-2017 IPR009003 Peptidase S1, PA clan RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 SUPERFAMILY SSF50494 111 298 1.97E-64 T 10-03-2017 IPR009003 Peptidase S1, PA clan RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 SUPERFAMILY SSF50156 399 471 2.76E-16 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 Gene3D G3DSA:2.40.10.10 38 178 2.3E-36 T 10-03-2017 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 Gene3D G3DSA:2.30.42.10 291 388 3.4E-29 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 SMART SM00228 289 371 9.7E-15 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 SMART SM00228 396 466 1.5E-9 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 Gene3D G3DSA:2.30.42.10 406 471 3.0E-20 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 Pfam PF13365 Trypsin-like peptidase domain 114 250 1.5E-32 T 10-03-2017 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 393 463 3.6E-12 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 287 367 2.5E-15 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 PRINTS PR00834 HtrA/DegQ protease family signature 145 165 2.6E-60 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 PRINTS PR00834 HtrA/DegQ protease family signature 186 210 2.6E-60 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 PRINTS PR00834 HtrA/DegQ protease family signature 124 136 2.6E-60 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 PRINTS PR00834 HtrA/DegQ protease family signature 221 238 2.6E-60 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 PRINTS PR00834 HtrA/DegQ protease family signature 243 260 2.6E-60 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 PRINTS PR00834 HtrA/DegQ protease family signature 329 341 2.6E-60 T 10-03-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 SUPERFAMILY SSF50156 271 379 1.26E-22 T 10-03-2017 IPR001478 PDZ domain GO:0005515 RG49_RS11015 fb8c2814f376b032973534386ddd20a2 474 Gene3D G3DSA:2.40.10.10 179 290 2.2E-44 T 10-03-2017 RG49_RS10205 e1534c82c158d98276fd48bff83fbc94 352 Pfam PF04865 Baseplate J-like protein 69 317 7.5E-60 T 10-03-2017 IPR006949 Baseplate protein J-like RG49_RS05655 39f5840e1d18ec1312d9f6ccdc93848d 196 SUPERFAMILY SSF55469 12 193 4.06E-39 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS05655 39f5840e1d18ec1312d9f6ccdc93848d 196 Pfam PF00881 Nitroreductase family 18 174 1.8E-13 T 10-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 RG49_RS05655 39f5840e1d18ec1312d9f6ccdc93848d 196 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 2 196 47.305 T 10-03-2017 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 RG49_RS05655 39f5840e1d18ec1312d9f6ccdc93848d 196 Gene3D G3DSA:3.40.109.10 9 193 1.7E-40 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS06415 50f7cddcd9c6d13b2ffeb66705a852d7 476 Gene3D G3DSA:3.40.50.720 3 221 1.3E-37 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06415 50f7cddcd9c6d13b2ffeb66705a852d7 476 Pfam PF11066 Protein of unknown function (DUF2867) 331 463 2.5E-12 T 10-03-2017 IPR021295 Protein of unknown function DUF2867 RG49_RS06415 50f7cddcd9c6d13b2ffeb66705a852d7 476 SUPERFAMILY SSF51735 3 294 1.08E-48 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06415 50f7cddcd9c6d13b2ffeb66705a852d7 476 Pfam PF13460 NAD(P)H-binding 9 155 1.8E-16 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS12270 1cf925c2747bbd9e5cb55f3730469704 587 SUPERFAMILY SSF116734 372 573 1.8E-39 T 10-03-2017 RG49_RS12270 1cf925c2747bbd9e5cb55f3730469704 587 Pfam PF01420 Type I restriction modification DNA specificity domain 407 558 2.0E-6 T 10-03-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 RG49_RS12270 1cf925c2747bbd9e5cb55f3730469704 587 Pfam PF01420 Type I restriction modification DNA specificity domain 102 278 1.7E-23 T 10-03-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 RG49_RS12270 1cf925c2747bbd9e5cb55f3730469704 587 SUPERFAMILY SSF116734 86 278 2.13E-47 T 10-03-2017 RG49_RS12270 1cf925c2747bbd9e5cb55f3730469704 587 SUPERFAMILY SSF116734 324 348 2.13E-47 T 10-03-2017 RG49_RS20600 35f510e5982c5686bd63f63d74e45036 535 Gene3D G3DSA:1.10.150.130 189 313 8.8E-5 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS20600 35f510e5982c5686bd63f63d74e45036 535 SUPERFAMILY SSF56349 188 516 1.24E-39 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS20600 35f510e5982c5686bd63f63d74e45036 535 Pfam PF00589 Phage integrase family 329 516 4.4E-20 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS20600 35f510e5982c5686bd63f63d74e45036 535 Gene3D G3DSA:1.10.443.10 326 516 2.8E-26 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS24155 c75bff5d958d3809695d48d596226a11 159 SUPERFAMILY SSF82093 30 143 4.45E-41 T 10-03-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 RG49_RS24155 c75bff5d958d3809695d48d596226a11 159 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 147 31.978 T 10-03-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 RG49_RS24155 c75bff5d958d3809695d48d596226a11 159 Pfam PF03100 CcmE 4 137 5.3E-46 T 10-03-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 RG49_RS24155 c75bff5d958d3809695d48d596226a11 159 Gene3D G3DSA:2.40.50.140 26 131 3.2E-42 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS22250 aafd6e66713fcf0b109289f673d6f7c6 86 Gene3D G3DSA:3.30.70.20 4 75 1.9E-17 T 10-03-2017 RG49_RS22250 aafd6e66713fcf0b109289f673d6f7c6 86 SUPERFAMILY SSF54862 5 68 1.77E-17 T 10-03-2017 RG49_RS22250 aafd6e66713fcf0b109289f673d6f7c6 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS22250 aafd6e66713fcf0b109289f673d6f7c6 86 Pfam PF00037 4Fe-4S binding domain 6 25 4.0E-6 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS21910 a45a8adef7f5cb6df6ffc5b6b9a26209 190 Pfam PF07455 Phage polarity suppression protein (Psu) 6 185 2.1E-63 T 10-03-2017 IPR010006 Bacteriophage P4, Psu, polarity suppression protein RG49_RS21910 a45a8adef7f5cb6df6ffc5b6b9a26209 190 ProDom PD037484 CAPSID DETERMINATION SIZE HEAD GLYCOPROTEIN SID MORPHOGENESIS CP-933I ENCODED LATE 66 172 0.008 T 10-03-2017 RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 Pfam PF13624 SurA N-terminal domain 1 165 2.5E-54 T 10-03-2017 RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 SUPERFAMILY SSF54534 225 355 3.34E-23 T 10-03-2017 RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 Gene3D G3DSA:1.10.3120.10 43 122 9.0E-4 T 10-03-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 Gene3D G3DSA:3.10.50.40 258 379 2.1E-29 T 10-03-2017 RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 295 316 - T 10-03-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 SUPERFAMILY SSF109998 203 239 4.32E-38 T 10-03-2017 IPR027304 Trigger factor/SurA domain RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 SUPERFAMILY SSF109998 39 169 4.32E-38 T 10-03-2017 IPR027304 Trigger factor/SurA domain RG49_RS08915 6107950a8bfdc532059d2b072baf9356 623 Pfam PF13145 PPIC-type PPIASE domain 247 369 4.1E-24 T 10-03-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 RG49_RS03815 c18e44d18f3dbd7d6c77a6fdd2e62b77 327 Hamap MF_01565 Zinc transport protein ZntB [zntB]. 1 327 72.982 T 10-03-2017 IPR023714 Zinc transport protein ZntB GO:0005385|GO:0005886|GO:0071577 RG49_RS03815 c18e44d18f3dbd7d6c77a6fdd2e62b77 327 Pfam PF01544 CorA-like Mg2+ transporter protein 39 323 8.4E-65 T 10-03-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 RG49_RS03815 c18e44d18f3dbd7d6c77a6fdd2e62b77 327 SUPERFAMILY SSF144083 263 324 4.71E-13 T 10-03-2017 RG49_RS03815 c18e44d18f3dbd7d6c77a6fdd2e62b77 327 Gene3D G3DSA:1.20.58.340 147 244 2.7E-15 T 10-03-2017 RG49_RS03815 c18e44d18f3dbd7d6c77a6fdd2e62b77 327 SUPERFAMILY SSF143865 8 255 1.22E-48 T 10-03-2017 RG49_RS03815 c18e44d18f3dbd7d6c77a6fdd2e62b77 327 Gene3D G3DSA:1.20.58.340 251 327 2.3E-18 T 10-03-2017 RG49_RS24065 c5f113d57e19da3dcb4576ffc9223fbd 216 SUPERFAMILY SSF51197 15 212 5.22E-63 T 10-03-2017 RG49_RS24065 c5f113d57e19da3dcb4576ffc9223fbd 216 TIGRFAM TIGR00568 alkb: alkylated DNA repair protein AlkB 22 189 5.6E-77 T 10-03-2017 IPR004574 Alkylated DNA repair protein AlkB GO:0006281|GO:0055114 RG49_RS24065 c5f113d57e19da3dcb4576ffc9223fbd 216 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 20 210 4.1E-56 T 10-03-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like RG49_RS24065 c5f113d57e19da3dcb4576ffc9223fbd 216 Gene3D G3DSA:2.60.120.590 15 214 6.5E-62 T 10-03-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like RG49_RS09825 a1cf19339661f10732cc1670fde78f0e 111 TIGRFAM TIGR01594 holin_lambda: phage holin, lambda family 1 109 1.9E-37 T 10-03-2017 IPR006481 Bacteriophage lambda, GpS, holin RG49_RS09825 a1cf19339661f10732cc1670fde78f0e 111 Pfam PF05106 Phage holin family (Lysis protein S) 3 105 5.4E-28 T 10-03-2017 IPR006481 Bacteriophage lambda, GpS, holin RG49_RS06910 72687302febc400acb6aaa54e09d2bef 306 Pfam PF03734 L,D-transpeptidase catalytic domain 101 231 3.1E-17 T 10-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 RG49_RS06910 72687302febc400acb6aaa54e09d2bef 306 SUPERFAMILY SSF141523 177 233 5.1E-26 T 10-03-2017 RG49_RS06910 72687302febc400acb6aaa54e09d2bef 306 SUPERFAMILY SSF141523 99 149 5.1E-26 T 10-03-2017 RG49_RS06910 72687302febc400acb6aaa54e09d2bef 306 Gene3D G3DSA:2.40.440.10 93 233 2.0E-33 T 10-03-2017 RG49_RS14775 0b62229bd733ec10578cb8a0e9b8fd9d 300 SUPERFAMILY SSF74650 14 293 3.64E-62 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS14775 0b62229bd733ec10578cb8a0e9b8fd9d 300 Pfam PF01263 Aldose 1-epimerase 12 292 3.9E-56 T 10-03-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 RG49_RS14775 0b62229bd733ec10578cb8a0e9b8fd9d 300 Gene3D G3DSA:2.70.98.10 11 293 4.7E-46 T 10-03-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 RG49_RS09325 7216e2451684f5ae9ff1af5bf6f61a91 193 SUPERFAMILY SSF51161 10 182 2.53E-30 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS09325 7216e2451684f5ae9ff1af5bf6f61a91 193 Gene3D G3DSA:2.160.10.10 8 181 1.4E-31 T 10-03-2017 RG49_RS09325 7216e2451684f5ae9ff1af5bf6f61a91 193 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 29 62 2.0E-8 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS09325 7216e2451684f5ae9ff1af5bf6f61a91 193 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 64 97 0.0026 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS19170 354a65fd7743ec916ea2b186331682d9 233 Gene3D G3DSA:2.60.120.10 3 231 1.1E-31 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS19170 354a65fd7743ec916ea2b186331682d9 233 PIRSF PIRSF006232 1 230 9.3E-33 T 10-03-2017 IPR012093 Pirin RG49_RS19170 354a65fd7743ec916ea2b186331682d9 233 Pfam PF02678 Pirin 4 119 4.6E-23 T 10-03-2017 IPR003829 Pirin, N-terminal domain RG49_RS19170 354a65fd7743ec916ea2b186331682d9 233 SUPERFAMILY SSF51182 1 231 2.39E-45 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 126 145 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 103 119 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 236 253 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 171 189 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 81 98 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 258 278 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 156 170 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 203 221 1.1E-87 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 Pfam PF02253 Phospholipase A1 43 285 2.2E-89 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 SUPERFAMILY SSF56931 39 288 3.01E-92 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS15085 3fe41c180d748b8b1949d7213bbc728e 289 Gene3D G3DSA:2.40.230.10 37 288 1.0E-101 T 10-03-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 Pfam PF05954 Phage late control gene D protein (GPD) 28 328 2.5E-73 T 10-03-2017 RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 SUPERFAMILY SSF69279 189 362 2.21E-44 T 10-03-2017 RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 Gene3D G3DSA:3.55.50.10 97 191 5.1E-32 T 10-03-2017 RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 20 500 7.6E-132 T 10-03-2017 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 SUPERFAMILY SSF69349 439 633 1.18E-31 T 10-03-2017 RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 7 517 2.9E-187 T 10-03-2017 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 SUPERFAMILY SSF69279 7 185 1.53E-48 T 10-03-2017 RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 SUPERFAMILY SSF69255 361 448 5.75E-33 T 10-03-2017 RG49_RS08335 ba950d2114234e065e26d0397398bd1e 633 Gene3D G3DSA:2.40.50.230 367 448 1.2E-40 T 10-03-2017 IPR006531 Gp5 N-terminal RG49_RS21400 189c6400fed384c7b60e434dd464cae6 218 Pfam PF00149 Calcineurin-like phosphoesterase 16 188 2.0E-16 T 10-03-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 RG49_RS21400 189c6400fed384c7b60e434dd464cae6 218 SUPERFAMILY SSF56300 6 217 3.49E-44 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS21400 189c6400fed384c7b60e434dd464cae6 218 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 74 79 - T 10-03-2017 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 RG49_RS21400 189c6400fed384c7b60e434dd464cae6 218 Gene3D G3DSA:3.60.21.10 4 217 7.4E-40 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS11485 b0d7e14348bbe9ca5277cc67cff46ff4 28 Pfam PF08054 Leucine operon leader peptide 1 28 2.5E-19 T 10-03-2017 IPR012570 Leucine operon leader peptide GO:0009098 RG49_RS17335 7ad1e15e18307c36eb0c20154b2d8db4 247 Gene3D G3DSA:3.20.20.190 3 240 2.5E-61 T 10-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 RG49_RS17335 7ad1e15e18307c36eb0c20154b2d8db4 247 SUPERFAMILY SSF51695 5 239 3.92E-63 T 10-03-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 RG49_RS17335 7ad1e15e18307c36eb0c20154b2d8db4 247 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 238 6.2E-42 T 10-03-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 RG49_RS15840 b2aac0f03eb34d4328fb96c850b370c9 149 PIRSF PIRSF007312 1 149 9.9E-100 T 10-03-2017 IPR016512 Uncharacterised protein family, inner membrane YidI RG49_RS16165 65fb447cec3050795b513dd9a2f962e2 205 Pfam PF03458 UPF0126 domain 91 164 7.2E-22 T 10-03-2017 IPR005115 Uncharacterised domain UPF0126 RG49_RS16165 65fb447cec3050795b513dd9a2f962e2 205 Pfam PF03458 UPF0126 domain 5 79 1.5E-18 T 10-03-2017 IPR005115 Uncharacterised domain UPF0126 RG49_RS03875 d0872fdca7764c1ba04cb966bae40205 85 Pfam PF10749 Protein of unknown function (DUF2534) 5 82 7.5E-40 T 10-03-2017 IPR019685 Protein of unknown function DUF2534 RG49_RS03900 222f6dd5ad5b5e8fa96c4f4148da425e 306 Gene3D G3DSA:3.40.50.1820 5 306 1.1E-63 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS03900 222f6dd5ad5b5e8fa96c4f4148da425e 306 SUPERFAMILY SSF53474 9 143 1.01E-39 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS03900 222f6dd5ad5b5e8fa96c4f4148da425e 306 SUPERFAMILY SSF53474 194 306 1.01E-39 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS03900 222f6dd5ad5b5e8fa96c4f4148da425e 306 Pfam PF12146 Serine aminopeptidase, S33 35 284 2.5E-7 T 10-03-2017 IPR022742 Serine aminopeptidase, S33 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 Gene3D G3DSA:3.40.190.10 98 183 3.5E-13 T 10-03-2017 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 Gene3D G3DSA:1.10.10.10 12 95 9.0E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 Gene3D G3DSA:3.40.190.10 184 274 7.2E-19 T 10-03-2017 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 4.7E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 4.7E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 4.7E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 SUPERFAMILY SSF53850 99 308 3.26E-33 T 10-03-2017 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 Pfam PF03466 LysR substrate binding domain 99 307 9.2E-30 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 76 3.1E-20 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 TIGRFAM TIGR02036 dsdC: D-serine deaminase transcriptional activator 8 308 8.7E-182 T 10-03-2017 IPR011781 D-serine deaminase transcriptional activator RG49_RS23330 e033bcc481d4fea7a552bb4894679a12 311 SUPERFAMILY SSF46785 17 123 4.57E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20730 f2e05782801f27394a24f17229411f6f 388 SUPERFAMILY SSF46894 21 102 5.39E-15 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS20730 f2e05782801f27394a24f17229411f6f 388 Gene3D G3DSA:1.10.10.10 23 102 5.7E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20730 f2e05782801f27394a24f17229411f6f 388 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 101 1.2E-12 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS20730 f2e05782801f27394a24f17229411f6f 388 SMART SM00862 27 101 8.5E-10 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS03660 67159906a30cbbd12496df80fd63ca88 399 SUPERFAMILY SSF103473 3 390 8.76E-52 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS03660 67159906a30cbbd12496df80fd63ca88 399 Pfam PF07690 Major Facilitator Superfamily 10 337 6.1E-36 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS03660 67159906a30cbbd12496df80fd63ca88 399 Gene3D G3DSA:1.20.1250.20 6 182 3.2E-22 T 10-03-2017 RG49_RS03660 67159906a30cbbd12496df80fd63ca88 399 Gene3D G3DSA:1.20.1250.20 202 389 9.8E-16 T 10-03-2017 RG49_RS09540 9ad8ffbceb86405433e36b45e4dd9c55 515 Pfam PF00549 CoA-ligase 346 503 8.6E-47 T 10-03-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS09540 9ad8ffbceb86405433e36b45e4dd9c55 515 Gene3D G3DSA:3.40.50.261 166 290 6.7E-22 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS09540 9ad8ffbceb86405433e36b45e4dd9c55 515 SUPERFAMILY SSF52210 349 507 8.33E-7 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS09540 9ad8ffbceb86405433e36b45e4dd9c55 515 Gene3D G3DSA:3.40.50.720 101 165 9.1E-4 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS09540 9ad8ffbceb86405433e36b45e4dd9c55 515 SUPERFAMILY SSF52210 180 288 1.57E-18 T 10-03-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 RG49_RS09540 9ad8ffbceb86405433e36b45e4dd9c55 515 Pfam PF02629 CoA binding domain 189 282 5.2E-15 T 10-03-2017 IPR003781 CoA-binding GO:0048037 RG49_RS24450 925db9b4ad38753374cef75e12d06554 239 Pfam PF02698 DUF218 domain 48 170 9.9E-18 T 10-03-2017 IPR003848 Domain of unknown function DUF218 RG49_RS24450 925db9b4ad38753374cef75e12d06554 239 Gene3D G3DSA:3.40.50.620 39 170 2.8E-8 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS24450 925db9b4ad38753374cef75e12d06554 239 PIRSF PIRSF005011 1 239 4.5E-157 T 10-03-2017 IPR023604 Uncharacterised protein family SanA RG49_RS04700 a9a7d65ac76c76eca701a94c40bf1a04 304 Pfam PF02016 LD-carboxypeptidase 6 284 8.8E-65 T 10-03-2017 IPR003507 Peptidase family S66 RG49_RS04700 a9a7d65ac76c76eca701a94c40bf1a04 304 PIRSF PIRSF028757 1 300 7.1E-91 T 10-03-2017 IPR003507 Peptidase family S66 RG49_RS04700 a9a7d65ac76c76eca701a94c40bf1a04 304 SUPERFAMILY SSF52317 5 160 1.69E-32 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS04700 a9a7d65ac76c76eca701a94c40bf1a04 304 SUPERFAMILY SSF141986 139 289 4.32E-43 T 10-03-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain RG49_RS04700 a9a7d65ac76c76eca701a94c40bf1a04 304 Gene3D G3DSA:3.40.50.10740 5 160 5.7E-40 T 10-03-2017 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain RG49_RS04700 a9a7d65ac76c76eca701a94c40bf1a04 304 Gene3D G3DSA:3.50.30.60 167 292 1.2E-43 T 10-03-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain RG49_RS10220 010334dc7135487e4a6c415783c846cf 359 Gene3D G3DSA:3.30.1920.10 201 272 2.2E-28 T 10-03-2017 IPR023399 Baseplate-like protein, two-layer sandwich domain RG49_RS10220 010334dc7135487e4a6c415783c846cf 359 PIRSF PIRSF004440 1 357 3.1E-99 T 10-03-2017 IPR026276 Baseplate protein GpP RG49_RS10220 010334dc7135487e4a6c415783c846cf 359 Gene3D G3DSA:3.55.50.10 106 176 1.8E-28 T 10-03-2017 RG49_RS10220 010334dc7135487e4a6c415783c846cf 359 Gene3D G3DSA:2.30.300.10 276 352 1.0E-74 T 10-03-2017 RG49_RS10220 010334dc7135487e4a6c415783c846cf 359 Gene3D G3DSA:2.30.300.10 1 105 1.0E-74 T 10-03-2017 RG49_RS10220 010334dc7135487e4a6c415783c846cf 359 SUPERFAMILY SSF69279 1 176 3.06E-53 T 10-03-2017 RG49_RS10220 010334dc7135487e4a6c415783c846cf 359 SUPERFAMILY SSF69279 179 342 6.8E-55 T 10-03-2017 RG49_RS04115 992c7121fd7b92a33849ca8a9138e991 375 SUPERFAMILY SSF69118 75 187 5.28E-10 T 10-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 RG49_RS04115 992c7121fd7b92a33849ca8a9138e991 375 SUPERFAMILY SSF69118 248 373 2.85E-12 T 10-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 RG49_RS04115 992c7121fd7b92a33849ca8a9138e991 375 Gene3D G3DSA:1.20.1290.10 266 374 6.1E-22 T 10-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 RG49_RS04115 992c7121fd7b92a33849ca8a9138e991 375 Gene3D G3DSA:1.20.1290.10 80 191 2.2E-13 T 10-03-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 RG49_RS05830 c79a8d3d94a915e99f5361bf6550c242 132 Gene3D G3DSA:3.40.30.10 19 101 2.2E-32 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS05830 c79a8d3d94a915e99f5361bf6550c242 132 Pfam PF07449 Hydrogenase-1 expression protein HyaE 10 116 5.8E-44 T 10-03-2017 IPR010893 [NiFe]-hydrogenase maturation factor HyaE RG49_RS05830 c79a8d3d94a915e99f5361bf6550c242 132 SUPERFAMILY SSF52833 5 130 1.1E-25 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 Pfam PF00239 Resolvase, N terminal domain 3 135 6.7E-51 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 SMART SM00857 2 136 4.1E-66 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 Gene3D G3DSA:1.10.10.60 138 185 1.8E-24 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 SUPERFAMILY SSF46689 138 184 1.57E-12 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 10-03-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 Pfam PF02796 Helix-turn-helix domain of resolvase 138 182 3.3E-14 T 10-03-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 Gene3D G3DSA:3.40.50.1390 1 119 5.5E-47 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS06580 46f2baaa53ce272ef21910d2deee1d01 188 SUPERFAMILY SSF53041 1 135 3.4E-49 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS15335 367b838d4f6b0eb5b91b7c0343ec34cd 149 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 8 142 7.2E-29 T 10-03-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 RG49_RS03230 ab513e2a1ddba4a69dd507d0de087189 653 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 10-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 RG49_RS03230 ab513e2a1ddba4a69dd507d0de087189 653 Pfam PF12392 Collagenase 391 505 5.1E-18 T 10-03-2017 IPR020988 Peptidase U32, collagenase RG49_RS03230 ab513e2a1ddba4a69dd507d0de087189 653 Pfam PF01136 Peptidase family U32 79 305 1.2E-71 T 10-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 RG49_RS15260 aacf3a27fabb374fda4f600a80125998 224 Hamap MF_02027 dTDP-fucosamine acetyltransferase [wecD]. 44 224 43.03 T 10-03-2017 IPR012752 dTDP-fucosamine acetyltransferase WecD GO:0008080|GO:0009246 KEGG: 00071+2.3.1.21|MetaCyc: PWY-6111|MetaCyc: PWY-7315 RG49_RS15260 aacf3a27fabb374fda4f600a80125998 224 SUPERFAMILY SSF55729 54 218 2.13E-16 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS15260 aacf3a27fabb374fda4f600a80125998 224 Gene3D G3DSA:3.40.630.30 88 218 2.2E-14 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS15260 aacf3a27fabb374fda4f600a80125998 224 TIGRFAM TIGR02382 wecD_rffC: TDP-D-fucosamine acetyltransferase 44 224 4.7E-97 T 10-03-2017 IPR012752 dTDP-fucosamine acetyltransferase WecD GO:0008080|GO:0009246 KEGG: 00071+2.3.1.21|MetaCyc: PWY-6111|MetaCyc: PWY-7315 RG49_RS21975 539969502e265520399f947fc5e72cec 288 Pfam PF01578 Cytochrome C assembly protein 62 286 6.8E-45 T 10-03-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 RG49_RS11840 e6d7f89842a6366856de47142438fb0a 195 SMART SM00852 7 153 1.4E-23 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS11840 e6d7f89842a6366856de47142438fb0a 195 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 69 82 - T 10-03-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 RG49_RS11840 e6d7f89842a6366856de47142438fb0a 195 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 4 146 2.2E-40 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS11840 e6d7f89842a6366856de47142438fb0a 195 Gene3D G3DSA:3.40.980.10 2 188 1.7E-54 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS11840 e6d7f89842a6366856de47142438fb0a 195 Pfam PF00994 Probable molybdopterin binding domain 8 147 5.8E-28 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS11840 e6d7f89842a6366856de47142438fb0a 195 SUPERFAMILY SSF53218 3 188 2.49E-49 T 10-03-2017 IPR001453 MoaB/Mog domain RG49_RS05075 73b02d4ad99a424c0b72a434a130c16e 85 Pfam PF07338 Protein of unknown function (DUF1471) 34 85 3.5E-19 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS05075 73b02d4ad99a424c0b72a434a130c16e 85 Gene3D G3DSA:3.30.1660.10 18 85 1.5E-26 T 10-03-2017 IPR025543 Dodecin-like RG49_RS05075 73b02d4ad99a424c0b72a434a130c16e 85 SUPERFAMILY SSF159871 3 85 2.62E-24 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS16325 1e3e4c86db4c77c02d00ccbbb709a1de 344 SUPERFAMILY SSF53448 7 225 2.34E-51 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS16325 1e3e4c86db4c77c02d00ccbbb709a1de 344 Gene3D G3DSA:3.90.550.10 3 207 6.7E-52 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS16325 1e3e4c86db4c77c02d00ccbbb709a1de 344 Pfam PF00535 Glycosyl transferase family 2 9 137 1.2E-33 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS09910 2865d8897774e838bff4918974a69fa5 348 Pfam PF08402 TOBE domain 273 344 6.8E-11 T 10-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 RG49_RS09910 2865d8897774e838bff4918974a69fa5 348 SUPERFAMILY SSF50331 240 344 2.67E-15 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS09910 2865d8897774e838bff4918974a69fa5 348 Pfam PF00005 ABC transporter 23 164 1.6E-37 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS09910 2865d8897774e838bff4918974a69fa5 348 SMART SM00382 31 214 5.2E-17 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS09910 2865d8897774e838bff4918974a69fa5 348 SUPERFAMILY SSF52540 7 245 4.56E-86 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09910 2865d8897774e838bff4918974a69fa5 348 Gene3D G3DSA:3.40.50.300 3 238 4.8E-83 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09910 2865d8897774e838bff4918974a69fa5 348 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS04905 6c2c3e8f66d18383cb3be881c7294c06 243 SMART SM00422 4 73 3.6E-29 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS04905 6c2c3e8f66d18383cb3be881c7294c06 243 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 30 - T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS04905 6c2c3e8f66d18383cb3be881c7294c06 243 Gene3D G3DSA:1.10.1660.10 4 87 1.3E-22 T 10-03-2017 RG49_RS04905 6c2c3e8f66d18383cb3be881c7294c06 243 Pfam PF13411 MerR HTH family regulatory protein 4 71 4.9E-19 T 10-03-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 RG49_RS04905 6c2c3e8f66d18383cb3be881c7294c06 243 SUPERFAMILY SSF46955 3 89 1.01E-20 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 40.702 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 SUPERFAMILY SSF55831 1 264 1.83E-132 T 10-03-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 1.6E-47 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 1.6E-47 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 1.6E-47 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 1.6E-47 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 1.6E-47 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 2.8E-42 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 8.1E-94 T 10-03-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 Gene3D G3DSA:3.30.572.10 1 264 5.3E-137 T 10-03-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 10-03-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS20905 188a9c3fc4031be2e94cdf304e4a6cb2 264 Pfam PF00303 Thymidylate synthase 2 264 2.2E-125 T 10-03-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 RG49_RS24265 f4d6a4e9b34cc52dd7429e43799388c1 604 Gene3D G3DSA:3.90.76.10 90 173 1.1E-13 T 10-03-2017 RG49_RS24265 f4d6a4e9b34cc52dd7429e43799388c1 604 SUPERFAMILY SSF53850 49 590 1.63E-108 T 10-03-2017 RG49_RS24265 f4d6a4e9b34cc52dd7429e43799388c1 604 Gene3D G3DSA:3.10.105.10 320 558 1.5E-45 T 10-03-2017 RG49_RS24265 f4d6a4e9b34cc52dd7429e43799388c1 604 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 504 7.2E-70 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS24265 f4d6a4e9b34cc52dd7429e43799388c1 604 PIRSF PIRSF002741 3 592 8.7E-184 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS24265 f4d6a4e9b34cc52dd7429e43799388c1 604 Gene3D G3DSA:3.40.190.10 174 319 5.0E-31 T 10-03-2017 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 50 178 6.6E-40 T 10-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 252 263 - T 10-03-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 25 185 25.255 T 10-03-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 SUPERFAMILY SSF56762 225 600 8.9E-119 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 215 600 4.0E-178 T 10-03-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 16 600 72.767 T 10-03-2017 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 105 160 1.0E-26 T 10-03-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 329 600 4.3E-102 T 10-03-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 138 159 - T 10-03-2017 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 49 176 4.0E-45 T 10-03-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 SUPERFAMILY SSF143243 25 229 1.24E-58 T 10-03-2017 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 Gene3D G3DSA:1.10.645.10 216 585 1.5E-45 T 10-03-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23660 df67d6cd1f4dccaa14e7bea09d5c729e 600 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 211 600 41.961 T 10-03-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22910 27876e37e64d1b27eb466bbf20749bb4 408 PIRSF PIRSF019466 1 408 1.4E-128 T 10-03-2017 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 RG49_RS22910 27876e37e64d1b27eb466bbf20749bb4 408 Pfam PF04346 Ethanolamine utilisation protein, EutH 3 391 9.6E-142 T 10-03-2017 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 RG49_RS17120 b249baeb6de05efde15bc8dd63e36430 535 Pfam PF13258 Domain of unknown function (DUF4049) 209 532 3.6E-201 T 10-03-2017 IPR025123 Domain of unknown function DUF4049 RG49_RS17120 b249baeb6de05efde15bc8dd63e36430 535 SUPERFAMILY SSF56300 291 401 2.78E-5 T 10-03-2017 IPR029052 Metallo-dependent phosphatase-like RG49_RS12765 ef23aa39d7fa5e452a998421f0e9cd7d 113 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 109 8.5E-25 T 10-03-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like RG49_RS12765 ef23aa39d7fa5e452a998421f0e9cd7d 113 SUPERFAMILY SSF110857 1 110 7.85E-35 T 10-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like RG49_RS12765 ef23aa39d7fa5e452a998421f0e9cd7d 113 Gene3D G3DSA:3.10.490.10 1 111 2.2E-40 T 10-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like RG49_RS05990 46cd86b0ab1a1ff8395460bbf4878e7e 180 Pfam PF07126 Cell-division protein ZapC 3 168 8.4E-69 T 10-03-2017 IPR009809 Cell division protein ZapC RG49_RS05990 46cd86b0ab1a1ff8395460bbf4878e7e 180 PIRSF PIRSF010252 1 179 1.7E-67 T 10-03-2017 IPR009809 Cell division protein ZapC RG49_RS05990 46cd86b0ab1a1ff8395460bbf4878e7e 180 Hamap MF_00906 Cell division protein ZapC [zapC]. 2 178 40.41 T 10-03-2017 IPR009809 Cell division protein ZapC RG49_RS21755 22983af105ce88325fc502be2cc0147d 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 2.1E-9 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS21755 22983af105ce88325fc502be2cc0147d 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 2.1E-9 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS21755 22983af105ce88325fc502be2cc0147d 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 2.1E-9 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS21755 22983af105ce88325fc502be2cc0147d 99 Pfam PF01022 Bacterial regulatory protein, arsR family 23 70 1.0E-14 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS21755 22983af105ce88325fc502be2cc0147d 99 SMART SM00418 16 95 1.8E-25 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS21755 22983af105ce88325fc502be2cc0147d 99 Gene3D G3DSA:1.10.10.10 3 98 2.1E-31 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21755 22983af105ce88325fc502be2cc0147d 99 SUPERFAMILY SSF46785 11 98 2.26E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20070 d3e155df63b4b26d95a6a761b36e6453 91 Gene3D G3DSA:1.10.3880.10 1 90 3.9E-44 T 10-03-2017 RG49_RS20070 d3e155df63b4b26d95a6a761b36e6453 91 SUPERFAMILY SSF111148 1 90 1.44E-40 T 10-03-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 RG49_RS20070 d3e155df63b4b26d95a6a761b36e6453 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 2.0E-39 T 10-03-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 RG49_RS20070 d3e155df63b4b26d95a6a761b36e6453 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.992 T 10-03-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 RG49_RS20070 d3e155df63b4b26d95a6a761b36e6453 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 87 2.0E-40 T 10-03-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 RG49_RS20070 d3e155df63b4b26d95a6a761b36e6453 91 PIRSF PIRSF029827 1 90 1.3E-44 T 10-03-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 RG49_RS13775 2baa029712212a12e240651cbb29557a 327 SUPERFAMILY SSF50129 5 144 7.39E-33 T 10-03-2017 IPR011032 GroES-like RG49_RS13775 2baa029712212a12e240651cbb29557a 327 Pfam PF00107 Zinc-binding dehydrogenase 152 258 3.8E-29 T 10-03-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 RG49_RS13775 2baa029712212a12e240651cbb29557a 327 Gene3D G3DSA:3.90.180.10 5 146 4.8E-43 T 10-03-2017 IPR011032 GroES-like RG49_RS13775 2baa029712212a12e240651cbb29557a 327 SMART SM00829 11 325 2.0E-26 T 10-03-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 RG49_RS13775 2baa029712212a12e240651cbb29557a 327 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 10-03-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 RG49_RS13775 2baa029712212a12e240651cbb29557a 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 1.9E-9 T 10-03-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 RG49_RS13775 2baa029712212a12e240651cbb29557a 327 SUPERFAMILY SSF51735 113 275 1.87E-47 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS13775 2baa029712212a12e240651cbb29557a 327 Gene3D G3DSA:3.40.50.720 147 256 1.1E-27 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 Hamap MF_01602 Lipoate-protein ligase A [lplA]. 1 338 59.709 T 10-03-2017 IPR023741 Lipoate-protein ligase A GO:0016979|GO:0018055 RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 158 3.6E-9 T 10-03-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 250 333 7.4E-18 T 10-03-2017 IPR019491 Lipoate protein ligase, C-terminal RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 1 329 1.6E-142 T 10-03-2017 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 Reactome: R-HSA-389661 RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 SUPERFAMILY SSF82649 248 335 1.31E-24 T 10-03-2017 RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 Gene3D G3DSA:3.90.1550.10 1 247 1.4E-85 T 10-03-2017 RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 SUPERFAMILY SSF55681 3 247 7.62E-82 T 10-03-2017 RG49_RS11985 23c2e395f3a1e630d3647906c2b3c4dd 338 Gene3D G3DSA:3.30.390.50 249 332 1.2E-13 T 10-03-2017 RG49_RS09345 f87f798f8fa665e7da0c36a02bb8e5ae 277 SUPERFAMILY SSF53474 1 275 4.86E-82 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS09345 f87f798f8fa665e7da0c36a02bb8e5ae 277 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 2 274 5.1E-119 T 10-03-2017 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 RG49_RS09345 f87f798f8fa665e7da0c36a02bb8e5ae 277 Pfam PF00756 Putative esterase 21 268 1.7E-76 T 10-03-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 RG49_RS09345 f87f798f8fa665e7da0c36a02bb8e5ae 277 Gene3D G3DSA:3.40.50.1820 1 275 6.0E-77 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS14390 6b0532d000b24ead7b35016dc226e4ca 367 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 150 178 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS14390 6b0532d000b24ead7b35016dc226e4ca 367 Gene3D G3DSA:3.40.50.1970 2 158 2.8E-44 T 10-03-2017 RG49_RS14390 6b0532d000b24ead7b35016dc226e4ca 367 Gene3D G3DSA:1.20.1090.10 160 364 1.6E-69 T 10-03-2017 RG49_RS14390 6b0532d000b24ead7b35016dc226e4ca 367 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 348 1.5E-63 T 10-03-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 RG49_RS14390 6b0532d000b24ead7b35016dc226e4ca 367 SUPERFAMILY SSF56796 3 355 3.27E-88 T 10-03-2017 RG49_RS14390 6b0532d000b24ead7b35016dc226e4ca 367 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 241 261 - T 10-03-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 RG49_RS14390 6b0532d000b24ead7b35016dc226e4ca 367 PIRSF PIRSF000112 1 360 4.5E-98 T 10-03-2017 RG49_RS06710 8f5f21ce0b000586ad7a26ff8c44c092 77 SUPERFAMILY SSF54857 1 77 6.02E-22 T 10-03-2017 IPR010391 DNA damage-inducible protein DinI-like RG49_RS06710 8f5f21ce0b000586ad7a26ff8c44c092 77 Pfam PF06183 DinI-like family 14 76 2.1E-21 T 10-03-2017 IPR010391 DNA damage-inducible protein DinI-like RG49_RS06710 8f5f21ce0b000586ad7a26ff8c44c092 77 Gene3D G3DSA:3.30.910.10 1 77 3.5E-27 T 10-03-2017 IPR010391 DNA damage-inducible protein DinI-like RG49_RS18390 887eea80c1f6bc0340bd975550c2e49c 1266 Pfam PF13502 AsmA-like C-terminal region 1009 1252 2.0E-68 T 10-03-2017 IPR032712 AsmA-like, C-terminal RG49_RS18390 887eea80c1f6bc0340bd975550c2e49c 1266 Pfam PF13116 Protein of unknown function 505 789 3.6E-97 T 10-03-2017 IPR025263 Domain of unknown function DUF3971 RG49_RS18390 887eea80c1f6bc0340bd975550c2e49c 1266 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 2 1262 0.0 T 10-03-2017 IPR011836 Conserved hypothetical protein CHP02099 RG49_RS21720 a29f59ebafce7e0553309b9794d32327 136 TIGRFAM TIGR00333 nrdI: nrdI protein 5 131 1.1E-62 T 10-03-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI RG49_RS21720 a29f59ebafce7e0553309b9794d32327 136 PIRSF PIRSF005087 1 136 1.9E-55 T 10-03-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI RG49_RS21720 a29f59ebafce7e0553309b9794d32327 136 Hamap MF_00128 Protein NrdI [nrdI]. 3 132 36.973 T 10-03-2017 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial RG49_RS21720 a29f59ebafce7e0553309b9794d32327 136 Gene3D G3DSA:3.40.50.360 4 132 9.3E-59 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS21720 a29f59ebafce7e0553309b9794d32327 136 Pfam PF07972 NrdI Flavodoxin like 5 122 2.6E-48 T 10-03-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI RG49_RS21720 a29f59ebafce7e0553309b9794d32327 136 SUPERFAMILY SSF52218 2 131 9.02E-24 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS06015 cf079588ac9e188e43b7c50a971b4474 356 Pfam PF00419 Fimbrial protein 211 355 1.8E-20 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS06015 cf079588ac9e188e43b7c50a971b4474 356 SUPERFAMILY SSF49401 219 355 9.44E-14 T 10-03-2017 IPR008966 Adhesion domain RG49_RS06015 cf079588ac9e188e43b7c50a971b4474 356 Gene3D G3DSA:2.60.40.1090 212 355 1.2E-10 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS17685 3f9afd2ff617e53301c95c1b6ef5a89e 387 Pfam PF01168 Alanine racemase, N-terminal domain 33 264 2.1E-22 T 10-03-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 RG49_RS17685 3f9afd2ff617e53301c95c1b6ef5a89e 387 Gene3D G3DSA:3.20.20.10 113 265 7.4E-9 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS17685 3f9afd2ff617e53301c95c1b6ef5a89e 387 SUPERFAMILY SSF51419 34 268 2.83E-24 T 10-03-2017 IPR029066 PLP-binding barrel RG49_RS12835 0c625ea629b944a8bfa50967e063bd0c 470 ProSitePatterns PS00218 Amino acid permeases signature. 52 82 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS12835 0c625ea629b944a8bfa50967e063bd0c 470 PIRSF PIRSF006060 1 469 7.4E-69 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS12835 0c625ea629b944a8bfa50967e063bd0c 470 Pfam PF00324 Amino acid permease 27 468 2.5E-124 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS10225 b81e7febde4a64fe618e63409cf73d31 442 Pfam PF07157 DNA circularisation protein N-terminus 7 93 9.9E-35 T 10-03-2017 IPR009826 DNA circulation, N-terminal RG49_RS10225 b81e7febde4a64fe618e63409cf73d31 442 ProDom PD332323 CIRCULATION DNA PROTEIN TAIL/DNA PHAGE PROPHAGE VIRION FLUMU BACTERIOPHAGE MU-LIKE 3 122 3.0E-67 T 10-03-2017 IPR009826 DNA circulation, N-terminal RG49_RS19310 22accb0a546c5e0ec3b89f972819ea13 783 Pfam PF01204 Trehalase 414 761 6.6E-11 T 10-03-2017 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 RG49_RS19310 22accb0a546c5e0ec3b89f972819ea13 783 SUPERFAMILY SSF48208 558 779 1.46E-85 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS19310 22accb0a546c5e0ec3b89f972819ea13 783 SUPERFAMILY SSF48208 270 530 1.46E-85 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS19250 cc63ccb0cace0874f345f5025aa13d41 495 SMART SM00858 10 81 3.7E-16 T 10-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 RG49_RS19250 cc63ccb0cace0874f345f5025aa13d41 495 Pfam PF08666 SAF domain 10 81 4.6E-15 T 10-03-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 RG49_RS19250 cc63ccb0cace0874f345f5025aa13d41 495 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 107 494 5.4E-155 T 10-03-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 RG49_RS11685 d9c8f73871e078c879e4ff865e64a61d 261 SUPERFAMILY SSF52096 2 261 4.69E-79 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS11685 d9c8f73871e078c879e4ff865e64a61d 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 260 5.2E-87 T 10-03-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 RG49_RS11685 d9c8f73871e078c879e4ff865e64a61d 261 Gene3D G3DSA:3.90.226.10 2 196 1.7E-67 T 10-03-2017 IPR029045 ClpP/crotonase-like domain RG49_RS11685 d9c8f73871e078c879e4ff865e64a61d 261 Gene3D G3DSA:1.10.12.10 200 261 1.8E-20 T 10-03-2017 IPR014748 Crontonase, C-terminal RG49_RS11685 d9c8f73871e078c879e4ff865e64a61d 261 Hamap MF_01051 Carnitinyl-CoA dehydratase [caiD]. 1 261 73.712 T 10-03-2017 IPR022852 Carnitinyl-CoA dehydratase GO:0016836 RG49_RS11685 d9c8f73871e078c879e4ff865e64a61d 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 10-03-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 Pfam PF00206 Lyase 12 342 2.7E-125 T 10-03-2017 IPR022761 Fumarate lyase, N-terminal RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 Gene3D G3DSA:1.10.275.10 3 138 3.2E-61 T 10-03-2017 IPR024083 Fumarase/histidase, N-terminal RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 SUPERFAMILY SSF48557 5 459 6.75E-160 T 10-03-2017 IPR008948 L-Aspartase-like GO:0003824 RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 1.3E-34 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 1.3E-34 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 1.3E-34 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 1.3E-34 T 10-03-2017 IPR000362 Fumarate lyase family RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 Gene3D G3DSA:1.20.200.10 139 416 5.2E-106 T 10-03-2017 RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 461 1.4E-255 T 10-03-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 Pfam PF10415 Fumarase C C-terminus 408 461 1.5E-25 T 10-03-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 10-03-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 462 92.247 T 10-03-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 RG49_RS02005 ba9ea4f2a2bede4d365c5a32e4fd7009 467 Gene3D G3DSA:1.10.40.30 417 462 5.8E-33 T 10-03-2017 RG49_RS20190 e84f0f71a44ddde5fb2cdbae2a17602b 71 ProDom PD056256 YQGC CYTOPLASMIC 1 51 5.0E-16 T 10-03-2017 IPR020102 Uncharacterised protein family YqgC RG49_RS13635 e648b260d82969eef4c78c3ff602feef 318 Gene3D G3DSA:1.20.1630.10 13 295 1.6E-7 T 10-03-2017 RG49_RS13635 e648b260d82969eef4c78c3ff602feef 318 Pfam PF03916 Polysulphide reductase, NrfD 5 318 1.7E-111 T 10-03-2017 IPR005614 NrfD family RG49_RS13635 e648b260d82969eef4c78c3ff602feef 318 TIGRFAM TIGR03148 cyt_nit_nrfD: cytochrome c nitrite reductase, NrfD subunit 5 318 4.7E-140 T 10-03-2017 IPR017566 NrfD RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 Gene3D G3DSA:3.60.15.10 262 385 3.7E-47 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 Gene3D G3DSA:3.60.15.10 118 219 3.7E-47 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 Pfam PF14863 Alkyl sulfatase dimerisation 392 530 4.3E-55 T 10-03-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 SMART SM00849 133 355 4.2E-27 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 SUPERFAMILY SSF55718 541 660 3.83E-29 T 10-03-2017 IPR003033 SCP2 sterol-binding domain RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 Pfam PF00753 Metallo-beta-lactamase superfamily 129 355 7.1E-50 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 Pfam PF14864 Alkyl sulfatase C-terminal 539 660 1.3E-32 T 10-03-2017 IPR029229 Alkyl sulfatase, C-terminal RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 SUPERFAMILY SSF56281 34 533 3.5E-149 T 10-03-2017 IPR001279 Metallo-beta-lactamase RG49_RS13570 b31029bc691faa786d63edf70f29f8d2 661 Gene3D G3DSA:3.30.1050.10 549 644 3.4E-5 T 10-03-2017 IPR003033 SCP2 sterol-binding domain RG49_RS23760 00926371a557641dc94145ad2fafee4b 101 Pfam PF05957 Bacterial protein of unknown function (DUF883) 9 101 1.4E-30 T 10-03-2017 IPR010279 Protein of unknown function DUF883, ElaB RG49_RS07980 2580a29ab0383932419deb2a2bdb7ef8 67 Pfam PF02416 mttA/Hcf106 family 4 51 3.4E-12 T 10-03-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 RG49_RS07980 2580a29ab0383932419deb2a2bdb7ef8 67 Hamap MF_00903 Probable Sec-independent protein translocase protein TatE [tatE]. 1 67 27.925 T 10-03-2017 IPR024905 Sec-independent protein translocase protein TatE RG49_RS07980 2580a29ab0383932419deb2a2bdb7ef8 67 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 62 21.266 T 10-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 RG49_RS07980 2580a29ab0383932419deb2a2bdb7ef8 67 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 47 2.0E-20 T 10-03-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 RG49_RS18860 e5b7ec13fe4fb6f2d6a310f11b24c6ac 292 Pfam PF01136 Peptidase family U32 92 198 3.9E-11 T 10-03-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 Gene3D G3DSA:2.30.38.10 533 609 5.4E-14 T 10-03-2017 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 Gene3D G3DSA:3.40.50.980 377 532 3.1E-40 T 10-03-2017 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 ProSitePatterns PS00455 Putative AMP-binding domain signature. 370 381 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 Gene3D G3DSA:3.30.300.30 617 716 1.1E-8 T 10-03-2017 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 Hamap MF_01162 Bifunctional protein Aas [aas]. 1 717 48.983 T 10-03-2017 IPR023775 Bifunctional protein Aas GO:0006631|GO:0008654|GO:0008779|GO:0008922 KEGG: 00071+6.2.1.20|KEGG: 00564+2.3.1.40|MetaCyc: PWY-6622|MetaCyc: PWY-7032 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 Pfam PF01553 Acyltransferase 15 137 4.2E-19 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 SUPERFAMILY SSF56801 219 712 1.83E-93 T 10-03-2017 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 Gene3D G3DSA:3.40.50.980 233 376 3.1E-15 T 10-03-2017 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 Pfam PF00501 AMP-binding enzyme 233 619 1.5E-65 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 SMART SM00563 30 140 3.4E-28 T 10-03-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 RG49_RS20850 b6563a329f81b8b7b406eacc500fac72 719 SUPERFAMILY SSF69593 3 170 7.72E-21 T 10-03-2017 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 306 3.2E-130 T 10-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 Pfam PF00814 Glycoprotease family 24 307 6.9E-103 T 10-03-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 7.3E-53 T 10-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 7.3E-53 T 10-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 7.3E-53 T 10-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 7.3E-53 T 10-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 7.3E-53 T 10-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 7.3E-53 T 10-03-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 10-03-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 SUPERFAMILY SSF53067 1 309 2.07E-44 T 10-03-2017 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 331 64.609 T 10-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 Gene3D G3DSA:3.30.420.40 1 159 1.4E-50 T 10-03-2017 RG49_RS19415 66e6ffda6e7d19a19beada717e5ad830 337 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 313 2.2E-136 T 10-03-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 RG49_RS03370 d1884c7738f3bf0bc0cee2f7efa8690f 430 Gene3D G3DSA:3.90.190.10 286 430 2.8E-23 T 10-03-2017 IPR029021 Protein-tyrosine phosphatase-like RG49_RS03370 d1884c7738f3bf0bc0cee2f7efa8690f 430 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 374 384 - T 10-03-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 RG49_RS03370 d1884c7738f3bf0bc0cee2f7efa8690f 430 SUPERFAMILY SSF52799 281 429 7.35E-25 T 10-03-2017 IPR029021 Protein-tyrosine phosphatase-like RG49_RS03370 d1884c7738f3bf0bc0cee2f7efa8690f 430 SMART SM00404 335 425 5.7E-4 T 10-03-2017 IPR003595 Protein-tyrosine phosphatase, catalytic RG49_RS03370 d1884c7738f3bf0bc0cee2f7efa8690f 430 Pfam PF00782 Dual specificity phosphatase, catalytic domain 306 429 2.0E-26 T 10-03-2017 IPR000340 Dual specificity phosphatase, catalytic domain GO:0006470|GO:0008138 RG49_RS03370 d1884c7738f3bf0bc0cee2f7efa8690f 430 SMART SM00195 298 430 5.3E-37 T 10-03-2017 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 RG49_RS20165 bf19bb159bc6957ac8dccfd73e5ec169 165 Hamap MF_00746 Protein SprT [sprT]. 12 165 41.456 T 10-03-2017 IPR023483 Uncharacterised protein family SprT RG49_RS20165 bf19bb159bc6957ac8dccfd73e5ec169 165 SMART SM00731 16 165 6.4E-62 T 10-03-2017 IPR006640 SprT-like RG49_RS20165 bf19bb159bc6957ac8dccfd73e5ec169 165 Pfam PF10263 SprT-like family 19 163 1.5E-27 T 10-03-2017 IPR006640 SprT-like RG49_RS05745 22d6146a6f8fda166566b0ed2143ac0f 57 Pfam PF08178 GnsA/GnsB toxin of bacterial toxin-antitoxin system 2 54 4.3E-35 T 10-03-2017 IPR012563 Gns RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 Gene3D G3DSA:2.40.33.10 77 170 1.7E-27 T 10-03-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 479 8.2E-176 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 Gene3D G3DSA:3.20.20.60 172 331 1.3E-93 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 Gene3D G3DSA:3.20.20.60 6 76 1.3E-93 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 218 230 - T 10-03-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 SUPERFAMILY SSF52935 329 479 2.35E-39 T 10-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 PRINTS PR01050 Pyruvate kinase family signature 300 318 4.2E-51 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 PRINTS PR01050 Pyruvate kinase family signature 319 335 4.2E-51 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 PRINTS PR01050 Pyruvate kinase family signature 63 79 4.2E-51 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 PRINTS PR01050 Pyruvate kinase family signature 275 299 4.2E-51 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 PRINTS PR01050 Pyruvate kinase family signature 250 274 4.2E-51 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 PRINTS PR01050 Pyruvate kinase family signature 190 204 4.2E-51 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 PRINTS PR01050 Pyruvate kinase family signature 223 249 4.2E-51 T 10-03-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 SUPERFAMILY SSF50800 74 168 1.74E-24 T 10-03-2017 IPR011037 Pyruvate kinase-like, insert domain RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 Pfam PF00224 Pyruvate kinase, barrel domain 6 344 6.7E-131 T 10-03-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 477 2.0E-29 T 10-03-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 SUPERFAMILY SSF51621 3 78 2.02E-86 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 SUPERFAMILY SSF51621 160 345 2.02E-86 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS00650 a48ece5c8d4b724f879abaeaa387af9f 480 Gene3D G3DSA:3.40.1380.20 332 480 1.3E-39 T 10-03-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 RG49_RS11205 ea6feaea04e6b919df2b03973e782854 146 Gene3D G3DSA:3.40.50.510 1 133 1.4E-31 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS11205 ea6feaea04e6b919df2b03973e782854 146 Pfam PF03610 PTS system fructose IIA component 3 116 9.3E-30 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS11205 ea6feaea04e6b919df2b03973e782854 146 SUPERFAMILY SSF53062 1 124 2.09E-29 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS11200 b26774612c6f6aadea625a7b0f20debf 409 Gene3D G3DSA:3.20.20.370 202 371 4.4E-21 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS11200 b26774612c6f6aadea625a7b0f20debf 409 SUPERFAMILY SSF88713 191 376 1.64E-28 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS11200 b26774612c6f6aadea625a7b0f20debf 409 Pfam PF01522 Polysaccharide deacetylase 228 366 2.9E-21 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS01100 fc2ab03840b63343b9e444654223b798 90 Pfam PF07023 Protein of unknown function (DUF1315) 5 80 1.9E-27 T 10-03-2017 IPR009749 Protein of unknown function DUF1315 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 Gene3D G3DSA:3.40.50.450 2 215 5.0E-76 T 10-03-2017 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 SUPERFAMILY SSF53784 3 309 5.23E-114 T 10-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 ProSitePatterns PS00433 Phosphofructokinase signature. 244 262 - T 10-03-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 301 2.9E-124 T 10-03-2017 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 2 320 47.102 T 10-03-2017 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PIRSF PIRSF000532 1 320 1.8E-131 T 10-03-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 Pfam PF00365 Phosphofructokinase 4 276 4.7E-107 T 10-03-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 32 45 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 240 262 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS14560 9f6606c2e93c6ac75fdc60dff2f54955 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 1.9E-82 T 10-03-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 RG49_RS10385 064adab1098354b3813a156c232ee4b4 313 Gene3D G3DSA:1.10.10.10 21 80 1.5E-7 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS10385 064adab1098354b3813a156c232ee4b4 313 SUPERFAMILY SSF46785 29 76 4.01E-6 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS10385 064adab1098354b3813a156c232ee4b4 313 Pfam PF13730 Helix-turn-helix domain 24 70 2.5E-10 T 10-03-2017 RG49_RS04525 e76d2cf421d530036f7632cf4ec6ba0d 117 Pfam PF02635 DsrE/DsrF-like family 2 117 1.8E-23 T 10-03-2017 IPR003787 Sulphur relay, DsrE/F-like protein RG49_RS04525 e76d2cf421d530036f7632cf4ec6ba0d 117 Gene3D G3DSA:3.40.1260.10 1 117 1.1E-45 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS04525 e76d2cf421d530036f7632cf4ec6ba0d 117 SUPERFAMILY SSF75169 1 117 1.57E-35 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 SUPERFAMILY SSF52540 106 494 4.43E-104 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 Gene3D G3DSA:3.40.50.300 228 494 9.3E-102 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 Pfam PF00437 Type II/IV secretion system protein 124 389 8.8E-89 T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 14 494 8.9E-214 T 10-03-2017 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 SUPERFAMILY SSF160246 13 76 2.88E-13 T 10-03-2017 RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 Gene3D G3DSA:3.30.450.90 93 222 1.3E-53 T 10-03-2017 RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 317 331 - T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS19995 f726613daa6a1629ba3133119609cc8a 497 SMART SM00382 250 373 0.0065 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS06620 5a44a1231b33abb2b35d77eaba983772 192 Pfam PF04717 Type VI secretion system, phage-baseplate injector 7 115 4.3E-44 T 10-03-2017 IPR006531 Gp5 N-terminal RG49_RS06620 5a44a1231b33abb2b35d77eaba983772 192 TIGRFAM TIGR01644 phage_P2_V: phage baseplate assembly protein V 8 190 1.3E-65 T 10-03-2017 IPR013046 Phage baseplate assembly protein V/Gp45 RG49_RS02735 1658433bfa0560efc3469f63422ccb54 446 Gene3D G3DSA:1.10.443.10 199 363 2.7E-15 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02735 1658433bfa0560efc3469f63422ccb54 446 Pfam PF00589 Phage integrase family 199 363 6.5E-7 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02735 1658433bfa0560efc3469f63422ccb54 446 SUPERFAMILY SSF56349 200 359 2.94E-13 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS20105 cbe860bf4f5ec7225571352465f17fd2 335 Pfam PF06717 Protein of unknown function (DUF1202) 14 320 1.1E-197 T 10-03-2017 IPR009592 Protein of unknown function DUF1202 RG49_RS19875 e285b8f667e13c1b5eca1fd2abd2b03a 82 Pfam PF00550 Phosphopantetheine attachment site 10 74 5.3E-13 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS19875 e285b8f667e13c1b5eca1fd2abd2b03a 82 ProSitePatterns PS00012 Phosphopantetheine attachment site. 34 49 - T 10-03-2017 IPR006162 Phosphopantetheine attachment site RG49_RS19875 e285b8f667e13c1b5eca1fd2abd2b03a 82 Gene3D G3DSA:1.10.1200.10 3 74 1.6E-14 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS19875 e285b8f667e13c1b5eca1fd2abd2b03a 82 SUPERFAMILY SSF47336 3 79 5.1E-16 T 10-03-2017 IPR009081 Phosphopantetheine binding ACP domain RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 337 225.684 T 10-03-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 272 335 4.0E-30 T 10-03-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 Gene3D G3DSA:1.10.8.60 275 336 1.6E-33 T 10-03-2017 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 Gene3D G3DSA:3.20.20.70 4 262 9.1E-59 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 Pfam PF00682 HMGL-like 6 262 3.2E-76 T 10-03-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 SUPERFAMILY SSF89000 288 335 3.49E-18 T 10-03-2017 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 SUPERFAMILY SSF51569 3 276 4.03E-69 T 10-03-2017 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 Pfam PF07836 DmpG-like communication domain 274 334 9.8E-31 T 10-03-2017 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS09370 0cecdc75cde2708ed60a5ea482fa9481 337 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 4 336 1.5E-181 T 10-03-2017 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 RG49_RS01180 5ce2ea2146876b530f6337277a034665 346 Pfam PF06889 Protein of unknown function (DUF1266) 167 338 4.2E-23 T 10-03-2017 IPR009677 Protein of unknown function DUF1266 RG49_RS18945 2ddd5d3ced6bd1964b5de3e768fb55dc 194 SUPERFAMILY SSF49401 27 193 6.46E-24 T 10-03-2017 IPR008966 Adhesion domain RG49_RS18945 2ddd5d3ced6bd1964b5de3e768fb55dc 194 Pfam PF00419 Fimbrial protein 28 193 3.4E-20 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS18945 2ddd5d3ced6bd1964b5de3e768fb55dc 194 Gene3D G3DSA:2.60.40.1090 25 193 1.0E-28 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS00945 e6576568a181edce2027623873528bdc 193 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 6 189 2.7E-89 T 10-03-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 RG49_RS00945 e6576568a181edce2027623873528bdc 193 PIRSF PIRSF004982 5 189 1.7E-58 T 10-03-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 RG49_RS00945 e6576568a181edce2027623873528bdc 193 Pfam PF03843 Outer membrane lipoprotein Slp family 20 167 5.2E-49 T 10-03-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 RG49_RS22260 f2662d77b49e68eeea0c795f1810dc75 211 Gene3D G3DSA:3.40.50.1000 99 129 6.8E-5 T 10-03-2017 IPR023214 HAD-like domain RG49_RS22260 f2662d77b49e68eeea0c795f1810dc75 211 Gene3D G3DSA:3.40.50.1000 4 29 6.8E-5 T 10-03-2017 IPR023214 HAD-like domain RG49_RS22260 f2662d77b49e68eeea0c795f1810dc75 211 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 192 2.6E-12 T 10-03-2017 RG49_RS22260 f2662d77b49e68eeea0c795f1810dc75 211 SUPERFAMILY SSF56784 6 137 2.24E-7 T 10-03-2017 IPR023214 HAD-like domain RG49_RS22260 f2662d77b49e68eeea0c795f1810dc75 211 TIGRFAM TIGR01545 YfhB_g-proteo: HAD hydrolase, family IF 2 211 4.5E-136 T 10-03-2017 IPR006435 HAD-superfamily hydrolase, subfamily IF, YfhB KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668 RG49_RS07145 050ade427d2757f7299794e0e575f71e 251 Pfam PF08241 Methyltransferase domain 47 138 1.8E-23 T 10-03-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 RG49_RS07145 050ade427d2757f7299794e0e575f71e 251 SUPERFAMILY SSF53335 10 244 1.22E-41 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS07145 050ade427d2757f7299794e0e575f71e 251 Gene3D G3DSA:3.40.50.150 10 200 3.9E-40 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS07145 050ade427d2757f7299794e0e575f71e 251 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 12 249 8.8E-78 T 10-03-2017 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 RG49_RS07145 050ade427d2757f7299794e0e575f71e 251 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 4 250 31.685 T 10-03-2017 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 RG49_RS24280 68710bdf4de7d9ca111a24d79be3bc6e 237 SMART SM00014 94 210 2.3E-22 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS24280 68710bdf4de7d9ca111a24d79be3bc6e 237 Gene3D G3DSA:1.20.144.10 23 205 1.1E-13 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS24280 68710bdf4de7d9ca111a24d79be3bc6e 237 Hamap MF_01945 Lipid A 1-diphosphate synthase [lpxT]. 1 233 41.709 T 10-03-2017 IPR032908 Lipid A 1-diphosphate synthase GO:0005886|GO:0043165|GO:0050380 RG49_RS24280 68710bdf4de7d9ca111a24d79be3bc6e 237 Pfam PF01569 PAP2 superfamily 133 207 1.0E-8 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS24280 68710bdf4de7d9ca111a24d79be3bc6e 237 SUPERFAMILY SSF48317 2 226 3.38E-36 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS02320 cf2f53c118f7842a10cf2fdd5e047818 71 PIRSF PIRSF030786 1 71 3.0E-44 T 10-03-2017 IPR007054 Lysis protein S RG49_RS02320 cf2f53c118f7842a10cf2fdd5e047818 71 Pfam PF04971 Bacteriophage P21 holin S 4 71 2.1E-47 T 10-03-2017 IPR007054 Lysis protein S RG49_RS15935 9353f8c1aae908466eb3e1e38a0f8a59 150 ProDom PD093913 YICN MEMBRANE INNER EXPORTED 1 145 3.0E-79 T 10-03-2017 IPR009587 Protein of unknown function DUF1198 RG49_RS15935 9353f8c1aae908466eb3e1e38a0f8a59 150 Pfam PF06711 Protein of unknown function (DUF1198) 1 142 4.2E-66 T 10-03-2017 IPR009587 Protein of unknown function DUF1198 RG49_RS08815 8c0fc28afdc8cc4f0ff842ba48eac564 156 Pfam PF10777 Inner membrane protein YlaC 1 152 8.8E-67 T 10-03-2017 IPR019713 Inner membrane protein YlaC RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 Gene3D G3DSA:1.10.10.10 8 105 6.9E-30 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 41 2.9E-26 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.9E-26 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.9E-26 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.9E-26 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 3.6E-17 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 32 50 - T 10-03-2017 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 SMART SM00418 8 86 3.7E-31 T 10-03-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 RG49_RS17035 5476ba71ab630fd81d8d88f6bc00a531 117 SUPERFAMILY SSF46785 7 106 6.47E-27 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06520 4954e971493e7256b7dd516ce78df469 95 Pfam PF07214 Protein of unknown function (DUF1418) 1 92 8.3E-37 T 10-03-2017 IPR010815 Protein of unknown function DUF1418 RG49_RS08520 fd06856f24fd292f2cf4369261edaacf 484 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 14 455 1.2E-138 T 10-03-2017 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 RG49_RS08520 fd06856f24fd292f2cf4369261edaacf 484 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 19 457 3.1E-141 T 10-03-2017 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 Pfam PF07720 Tetratricopeptide repeat 74 107 5.0E-11 T 10-03-2017 IPR011716 Tetratricopeptide TPR-3 RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 Pfam PF07720 Tetratricopeptide repeat 40 73 4.5E-11 T 10-03-2017 IPR011716 Tetratricopeptide TPR-3 RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 PIRSF PIRSF003165 1 163 5.4E-52 T 10-03-2017 IPR016379 Type III secretion system, low calcium response, chaperone LcrH/SycD, subgroup RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 SUPERFAMILY SSF48452 32 144 6.83E-9 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 Gene3D G3DSA:1.25.40.10 37 151 8.8E-7 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 26 49 2.1E-6 T 10-03-2017 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 75 97 2.1E-6 T 10-03-2017 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 RG49_RS20740 5444ce373fc6777ca03ce5bbf90ff67e 163 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 51 70 2.1E-6 T 10-03-2017 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 RG49_RS12280 f6aad2ca358ac827f8463cc71c770600 697 Pfam PF03235 Protein of unknown function DUF262 9 222 1.6E-32 T 10-03-2017 IPR004919 Domain of unknown function DUF262 RG49_RS12280 f6aad2ca358ac827f8463cc71c770600 697 Pfam PF07510 Protein of unknown function (DUF1524) 414 547 2.0E-29 T 10-03-2017 IPR011089 Domain of unknown function DUF1524 RG49_RS02540 7c35f953fbd5e02085ca5a182ddbfcf0 296 Pfam PF13682 Chemoreceptor zinc-binding domain 22 89 7.1E-5 T 10-03-2017 IPR025991 Chemoreceptor zinc-binding domain RG49_RS02540 7c35f953fbd5e02085ca5a182ddbfcf0 296 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 128 285 1.4E-38 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02540 7c35f953fbd5e02085ca5a182ddbfcf0 296 Pfam PF00990 Diguanylate cyclase, GGDEF domain 130 283 1.2E-44 T 10-03-2017 IPR000160 GGDEF domain RG49_RS02540 7c35f953fbd5e02085ca5a182ddbfcf0 296 SUPERFAMILY SSF55073 134 289 5.49E-41 T 10-03-2017 IPR029787 Nucleotide cyclase RG49_RS02540 7c35f953fbd5e02085ca5a182ddbfcf0 296 Gene3D G3DSA:3.30.70.270 131 290 1.1E-45 T 10-03-2017 RG49_RS02540 7c35f953fbd5e02085ca5a182ddbfcf0 296 SMART SM00267 118 287 6.6E-61 T 10-03-2017 IPR000160 GGDEF domain RG49_RS05415 9c4970a407bfa883aec2c648e782e773 385 Pfam PF01757 Acyltransferase family 10 356 1.4E-41 T 10-03-2017 IPR002656 Acyltransferase 3 GO:0016747 RG49_RS05415 9c4970a407bfa883aec2c648e782e773 385 Hamap MF_01066 Glucans biosynthesis protein C [mdoC]. 1 385 55.668 T 10-03-2017 IPR023723 Glucan biosynthesis protein C GO:0016741 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 Pfam PF00708 Acylphosphatase 9 91 1.1E-17 T 10-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 Pfam PF07503 HypF finger 158 191 5.8E-17 T 10-03-2017 IPR011125 Zinc finger, HypF-type GO:0008270 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 Pfam PF07503 HypF finger 108 141 5.6E-16 T 10-03-2017 IPR011125 Zinc finger, HypF-type GO:0008270 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 SUPERFAMILY SSF55821 175 379 1.01E-44 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 Gene3D G3DSA:3.90.870.10 197 369 3.8E-45 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 PIRSF PIRSF006256 4 748 6.9E-281 T 10-03-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 Gene3D G3DSA:3.30.70.100 3 91 3.3E-28 T 10-03-2017 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 ProSitePatterns PS00150 Acylphosphatase signature 1. 13 23 - T 10-03-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 Pfam PF01300 Telomere recombination 210 373 9.3E-47 T 10-03-2017 IPR006070 YrdC-like domain GO:0003725 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 11 738 0.0 T 10-03-2017 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 RG49_RS21520 a0187f1fd3acf7d88bc1dbaa958a3b92 750 SUPERFAMILY SSF54975 8 91 1.31E-20 T 10-03-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 RG49_RS18930 60182bfd2e8963595c08ea4ed8eb23a1 363 SUPERFAMILY SSF49401 219 360 4.91E-14 T 10-03-2017 IPR008966 Adhesion domain RG49_RS18930 60182bfd2e8963595c08ea4ed8eb23a1 363 Pfam PF00419 Fimbrial protein 212 362 2.8E-22 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS08865 7425101048cecf93418f55c3037cb6be 428 ProSitePatterns PS01219 Ammonium transporters signature. 182 207 - T 10-03-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 RG49_RS08865 7425101048cecf93418f55c3037cb6be 428 Pfam PF00909 Ammonium Transporter Family 33 426 2.6E-131 T 10-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 RG49_RS08865 7425101048cecf93418f55c3037cb6be 428 Gene3D G3DSA:1.10.3430.10 26 407 2.2E-140 T 10-03-2017 IPR029020 Ammonium/urea transporter RG49_RS08865 7425101048cecf93418f55c3037cb6be 428 TIGRFAM TIGR00836 amt: ammonium transporter 31 426 8.1E-140 T 10-03-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 RG49_RS08865 7425101048cecf93418f55c3037cb6be 428 SUPERFAMILY SSF111352 27 407 8.37E-129 T 10-03-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 RG49_RS03105 5b4d151cca8a15962918059cd7d19d8d 70 ProDom PD055765 YNCH ECS2059 1 70 2.0E-33 T 10-03-2017 IPR020099 Uncharacterised protein family YncH RG49_RS06690 c982b9d784b41f0e765318b9d49dd7d1 345 PIRSF PIRSF018494 2 344 2.7E-156 T 10-03-2017 IPR030935 Phage portal protein PBSX family, Proteobacteria RG49_RS06690 c982b9d784b41f0e765318b9d49dd7d1 345 Pfam PF04860 Phage portal protein 96 325 3.1E-14 T 10-03-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein RG49_RS06690 c982b9d784b41f0e765318b9d49dd7d1 345 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 53 333 6.8E-111 T 10-03-2017 IPR006430 Phage portal protein PBSX family RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 27 137 5.9E-45 T 10-03-2017 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 Pfam PF00576 HIUase/Transthyretin family 29 136 4.2E-38 T 10-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 SMART SM00095 24 136 8.1E-4 T 10-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 PRINTS PR00189 Transthyretin signature 115 137 1.1E-13 T 10-03-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 PRINTS PR00189 Transthyretin signature 28 48 1.1E-13 T 10-03-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 PRINTS PR00189 Transthyretin signature 60 85 1.1E-13 T 10-03-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 ProSitePatterns PS00768 Transthyretin signature 1. 32 47 - T 10-03-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 SUPERFAMILY SSF49472 26 137 3.66E-43 T 10-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 ProSitePatterns PS00769 Transthyretin signature 2. 120 132 - T 10-03-2017 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS00040 d2746611cc5570bac58fe123700fa606 137 Gene3D G3DSA:2.60.40.180 25 137 5.1E-44 T 10-03-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 RG49_RS07560 dc5db9bfbf141178375c276cbb923c91 253 Pfam PF01609 Transposase DDE domain 102 232 7.8E-16 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS07560 dc5db9bfbf141178375c276cbb923c91 253 Pfam PF13808 DDE_Tnp_1-associated 7 94 2.6E-31 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 441 1.6E-167 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 PRINTS PR00175 Sodium/alanine symporter signature 206 225 6.1E-54 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 PRINTS PR00175 Sodium/alanine symporter signature 349 371 6.1E-54 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 PRINTS PR00175 Sodium/alanine symporter signature 87 109 6.1E-54 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 PRINTS PR00175 Sodium/alanine symporter signature 178 196 6.1E-54 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 PRINTS PR00175 Sodium/alanine symporter signature 410 430 6.1E-54 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 PRINTS PR00175 Sodium/alanine symporter signature 303 321 6.1E-54 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 Pfam PF01235 Sodium:alanine symporter family 52 453 2.2E-142 T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS11850 a5c1f3263bf5314c89fdfba02cbc3a7f 476 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 10-03-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 RG49_RS25205 af9d57342cbb58697c3cf4108cfcfd1a 308 Gene3D G3DSA:2.40.440.10 91 232 3.0E-36 T 10-03-2017 RG49_RS25205 af9d57342cbb58697c3cf4108cfcfd1a 308 Pfam PF03734 L,D-transpeptidase catalytic domain 97 231 3.4E-20 T 10-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 RG49_RS25205 af9d57342cbb58697c3cf4108cfcfd1a 308 SUPERFAMILY SSF141523 175 232 8.37E-29 T 10-03-2017 RG49_RS25205 af9d57342cbb58697c3cf4108cfcfd1a 308 SUPERFAMILY SSF141523 96 147 8.37E-29 T 10-03-2017 RG49_RS22970 fba85d05d695ab68cf36684c692a2b64 299 SUPERFAMILY SSF54909 1 296 1.45E-90 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS22970 fba85d05d695ab68cf36684c692a2b64 299 Pfam PF04261 Dyp-type peroxidase family 5 295 3.3E-98 T 10-03-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 RG49_RS22970 fba85d05d695ab68cf36684c692a2b64 299 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 5 296 1.5E-90 T 10-03-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 RG49_RS06280 abc501f5c77c7a30b01513b7fa11f8ce 203 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 9 201 33.028 T 10-03-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 RG49_RS06280 abc501f5c77c7a30b01513b7fa11f8ce 203 SUPERFAMILY SSF89392 22 202 1.22E-57 T 10-03-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX RG49_RS06280 abc501f5c77c7a30b01513b7fa11f8ce 203 Gene3D G3DSA:2.50.20.10 23 203 6.7E-61 T 10-03-2017 RG49_RS06280 abc501f5c77c7a30b01513b7fa11f8ce 203 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 1 203 5.6E-124 T 10-03-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 RG49_RS06280 abc501f5c77c7a30b01513b7fa11f8ce 203 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 33 191 1.1E-58 T 10-03-2017 IPR004564 Outer membrane lipoprotein carrier protein LolA-like RG49_RS02640 bc40d26e6f0eb4747f7ca30cf9c0f29c 96 Hamap MF_02051 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [lsrG]. 1 96 35.927 T 10-03-2017 IPR033672 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase GO:0016853 RG49_RS02640 bc40d26e6f0eb4747f7ca30cf9c0f29c 96 Gene3D G3DSA:3.30.70.900 1 90 1.3E-27 T 10-03-2017 RG49_RS02640 bc40d26e6f0eb4747f7ca30cf9c0f29c 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.3E-16 T 10-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain RG49_RS02640 bc40d26e6f0eb4747f7ca30cf9c0f29c 96 SUPERFAMILY SSF54909 1 94 2.56E-25 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 Gene3D G3DSA:2.40.30.10 158 207 8.6E-9 T 10-03-2017 RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 Gene3D G3DSA:2.40.30.10 3 32 8.6E-9 T 10-03-2017 RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 Pfam PF00297 Ribosomal protein L3 27 182 1.0E-14 T 10-03-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 Gene3D G3DSA:4.10.960.10 77 157 2.8E-35 T 10-03-2017 RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 204 2.2E-92 T 10-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 207 40.756 T 10-03-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 SUPERFAMILY SSF50447 1 208 8.65E-81 T 10-03-2017 IPR009000 Translation protein, beta-barrel domain RG49_RS18000 4c31ca787dff2e8979a12d5731b91705 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 10-03-2017 IPR019926 Ribosomal protein L3, conserved site RG49_RS17855 04826ee02de2e8ea82315341ca3f5b4e 66 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 3 60 6.1E-32 T 10-03-2017 IPR012658 Conserved hypothetical protein CHP02443 RG49_RS17855 04826ee02de2e8ea82315341ca3f5b4e 66 Pfam PF09526 Probable metal-binding protein (DUF2387) 4 54 2.5E-18 T 10-03-2017 IPR012658 Conserved hypothetical protein CHP02443 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 Pfam PF01336 OB-fold nucleic acid binding domain 68 146 5.3E-15 T 10-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 14 504 1.1E-239 T 10-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 PIRSF PIRSF039101 1 505 3.0E-206 T 10-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 501 9.0E-83 T 10-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 1.1E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 1.1E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 1.1E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 1.1E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 1.1E-39 T 10-03-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 SUPERFAMILY SSF55681 162 502 1.78E-123 T 10-03-2017 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 Gene3D G3DSA:3.30.930.10 157 500 8.1E-124 T 10-03-2017 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 SUPERFAMILY SSF50249 13 155 1.79E-48 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 505 45.643 T 10-03-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 RG49_RS20450 4c9ded869bb1ac9a20840200279bf143 505 Gene3D G3DSA:2.40.50.140 16 154 4.1E-50 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 Hamap MF_01577 Putative multidrug resistance protein MdtD [mdtD]. 1 465 54.228 T 10-03-2017 IPR023721 Multidrug resistance protein MdtD, putative RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 Gene3D G3DSA:1.20.1250.20 257 460 3.2E-14 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 Gene3D G3DSA:1.20.1250.20 10 193 2.1E-31 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 413 4.8E-71 T 10-03-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 Pfam PF07690 Major Facilitator Superfamily 15 405 3.4E-50 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 2.3E-9 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 2.3E-9 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 2.3E-9 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 2.3E-9 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 160 184 2.3E-9 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 2.3E-9 T 10-03-2017 RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 SUPERFAMILY SSF103473 244 452 3.92E-61 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS24790 48c58456901852eaa347ef52364b6ad1 471 SUPERFAMILY SSF103473 8 194 3.92E-61 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS14805 8cf28b83c9925bf9393fbbbb9a4e1d00 421 Pfam PF07690 Major Facilitator Superfamily 32 365 1.4E-22 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS14805 8cf28b83c9925bf9393fbbbb9a4e1d00 421 Gene3D G3DSA:1.20.1250.20 12 197 4.0E-19 T 10-03-2017 RG49_RS14805 8cf28b83c9925bf9393fbbbb9a4e1d00 421 Gene3D G3DSA:1.20.1250.20 213 415 1.4E-16 T 10-03-2017 RG49_RS14805 8cf28b83c9925bf9393fbbbb9a4e1d00 421 SUPERFAMILY SSF103473 3 414 7.46E-46 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS00865 47db7125f51b03a68b3081b13ec28e24 152 Pfam PF06173 Protein of unknown function (DUF986) 4 150 4.8E-62 T 10-03-2017 IPR009328 Protein of unknown function DUF986 RG49_RS00865 47db7125f51b03a68b3081b13ec28e24 152 Hamap MF_01071 UPF0266 membrane protein YobD [yobD]. 1 152 32.437 T 10-03-2017 IPR009328 Protein of unknown function DUF986 RG49_RS00865 47db7125f51b03a68b3081b13ec28e24 152 PIRSF PIRSF020687 1 152 5.1E-69 T 10-03-2017 IPR009328 Protein of unknown function DUF986 RG49_RS00865 47db7125f51b03a68b3081b13ec28e24 152 ProDom PD091196 MEMBRANE UPF0266 TRANSMEMBRANE INNER YOBD PLU2700 LMO0779 PM0830 YPO1755/Y2554/YP1637 LIN0773 21 148 3.0E-69 T 10-03-2017 IPR009328 Protein of unknown function DUF986 RG49_RS03120 fd3ba7bceb467a0105a3d00a8dd4a8e9 353 SUPERFAMILY SSF51004 34 337 1.96E-39 T 10-03-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain RG49_RS03120 fd3ba7bceb467a0105a3d00a8dd4a8e9 353 Gene3D G3DSA:2.130.10.10 46 333 1.2E-36 T 10-03-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 RG49_RS02890 aaa12b35867f101c0057294ada43f71f 193 Pfam PF01427 D-ala-D-ala dipeptidase 4 186 1.4E-81 T 10-03-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 RG49_RS02890 aaa12b35867f101c0057294ada43f71f 193 PIRSF PIRSF026671 1 186 3.3E-57 T 10-03-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 RG49_RS02890 aaa12b35867f101c0057294ada43f71f 193 SUPERFAMILY SSF55166 6 170 1.6E-55 T 10-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 RG49_RS02890 aaa12b35867f101c0057294ada43f71f 193 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 6 181 27.405 T 10-03-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 RG49_RS02890 aaa12b35867f101c0057294ada43f71f 193 Gene3D G3DSA:3.30.1380.10 5 171 2.3E-58 T 10-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 RG49_RS17260 3ed844d1b49fbe63afcfc819444fda72 352 TIGRFAM TIGR00439 ftsX: putative protein insertion permease FtsX 47 352 2.0E-161 T 10-03-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 RG49_RS17260 3ed844d1b49fbe63afcfc819444fda72 352 PIRSF PIRSF003097 50 348 3.9E-110 T 10-03-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 RG49_RS17260 3ed844d1b49fbe63afcfc819444fda72 352 Pfam PF02687 FtsX-like permease family 228 342 2.3E-11 T 10-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 RG49_RS18250 de5bdeed68994facad6ccc8ba26eacd1 367 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 174 360 3.8E-26 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18250 de5bdeed68994facad6ccc8ba26eacd1 367 Gene3D G3DSA:1.10.3720.10 153 361 8.1E-38 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18250 de5bdeed68994facad6ccc8ba26eacd1 367 SUPERFAMILY SSF161098 154 346 1.02E-34 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18250 de5bdeed68994facad6ccc8ba26eacd1 367 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 156 252 6.2E-20 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS03395 a446d8449f92057de7a38c692b9e0135 196 SUPERFAMILY SSF51161 2 168 2.63E-45 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS03395 a446d8449f92057de7a38c692b9e0135 196 TIGRFAM TIGR02287 PaaY: phenylacetic acid degradation protein PaaY 3 195 9.9E-115 T 10-03-2017 IPR011974 Phenylacetic acid degradation protein PaaY RG49_RS03395 a446d8449f92057de7a38c692b9e0135 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 45 6.4E-5 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS03395 a446d8449f92057de7a38c692b9e0135 196 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 1.0E-7 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS03395 a446d8449f92057de7a38c692b9e0135 196 Gene3D G3DSA:2.160.10.10 2 168 4.1E-42 T 10-03-2017 RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 Pfam PF12798 4Fe-4S binding domain 131 151 0.05 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 Gene3D G3DSA:3.30.70.20 70 95 6.5E-20 T 10-03-2017 RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 Pfam PF12800 4Fe-4S binding domain 10 22 0.4 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 Pfam PF13247 4Fe-4S dicluster domain 55 104 3.3E-8 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 Gene3D G3DSA:3.30.70.20 96 167 2.9E-15 T 10-03-2017 RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 Gene3D G3DSA:3.30.70.20 6 69 2.5E-9 T 10-03-2017 RG49_RS21515 cc70f09fe5af29105781fd3a8a15181b 175 SUPERFAMILY SSF54862 1 170 4.13E-42 T 10-03-2017 RG49_RS01950 db01e3168339eccf89562d127e8aba85 390 Pfam PF00155 Aminotransferase class I and II 30 379 5.3E-60 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS01950 db01e3168339eccf89562d127e8aba85 390 Gene3D G3DSA:3.40.640.10 44 250 1.6E-41 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS01950 db01e3168339eccf89562d127e8aba85 390 SUPERFAMILY SSF53383 1 386 3.23E-83 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS01950 db01e3168339eccf89562d127e8aba85 390 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 386 1.8E-113 T 10-03-2017 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 RG49_RS01950 db01e3168339eccf89562d127e8aba85 390 Gene3D G3DSA:3.90.1150.10 251 387 5.2E-42 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS02595 9a7c1fdf9e834ccf08e26c757886bbb4 462 Gene3D G3DSA:3.40.605.10 11 247 1.6E-72 T 10-03-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 RG49_RS02595 9a7c1fdf9e834ccf08e26c757886bbb4 462 Gene3D G3DSA:3.40.309.10 248 432 5.5E-63 T 10-03-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 RG49_RS02595 9a7c1fdf9e834ccf08e26c757886bbb4 462 SUPERFAMILY SSF53720 9 460 6.54E-143 T 10-03-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 RG49_RS02595 9a7c1fdf9e834ccf08e26c757886bbb4 462 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 261 272 - T 10-03-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 RG49_RS02595 9a7c1fdf9e834ccf08e26c757886bbb4 462 Pfam PF00171 Aldehyde dehydrogenase family 10 457 3.3E-141 T 10-03-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 RG49_RS17920 f7eedf512dcd2ecef19d0652fbafd476 64 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 51 1.2E-14 T 10-03-2017 IPR007419 BFD-like [2Fe-2S]-binding domain RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 SUPERFAMILY SSF81442 43 560 5.23E-180 T 10-03-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 Gene3D G3DSA:1.20.210.10 40 589 1.2E-190 T 10-03-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 504 1.6E-135 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 10-03-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 647 0.0 T 10-03-2017 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08975 d538bcaafd2c39381572efd93acd371d 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 3.2E-94 T 10-03-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS02060 d99504d69de835a8516b33bbf623b36c 344 Pfam PF01594 Domain of unknown function DUF20 14 328 5.0E-77 T 10-03-2017 IPR002549 Transmembrane protein TqsA-like RG49_RS12775 a81b75e62a698fa53de70913e5ea9f07 577 Pfam PF01103 Surface antigen 284 574 3.5E-31 T 10-03-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 RG49_RS12775 a81b75e62a698fa53de70913e5ea9f07 577 Gene3D G3DSA:2.40.160.50 307 574 1.6E-21 T 10-03-2017 RG49_RS12775 a81b75e62a698fa53de70913e5ea9f07 577 Pfam PF07244 Surface antigen variable number repeat 189 252 2.6E-8 T 10-03-2017 IPR010827 Surface antigen variable number GO:0019867 RG49_RS05045 eb86abe3a553dee6e1d891af3baf67a5 414 TIGRFAM TIGR02213 lolE_release: lipoprotein releasing system, transmembrane protein LolE 5 414 2.7E-238 T 10-03-2017 IPR011926 Lipoprotein-releasing system transmembrane protein LolC/E, gammaproteobacteria type GO:0006810|GO:0009276|GO:0016021 RG49_RS05045 eb86abe3a553dee6e1d891af3baf67a5 414 Pfam PF02687 FtsX-like permease family 274 407 7.5E-20 T 10-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 RG49_RS05045 eb86abe3a553dee6e1d891af3baf67a5 414 Pfam PF12704 MacB-like periplasmic core domain 27 239 9.4E-16 T 10-03-2017 IPR025857 MacB-like periplasmic core domain RG49_RS05045 eb86abe3a553dee6e1d891af3baf67a5 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 413 3.3E-167 T 10-03-2017 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 RG49_RS04910 900cd4841f32617ff6290456e98f72a1 134 SUPERFAMILY SSF160419 3 127 5.49E-43 T 10-03-2017 IPR009833 Uncharacterised protein DUF1398 RG49_RS04910 900cd4841f32617ff6290456e98f72a1 134 Pfam PF07166 Protein of unknown function (DUF1398) 8 125 7.1E-45 T 10-03-2017 IPR009833 Uncharacterised protein DUF1398 RG49_RS04910 900cd4841f32617ff6290456e98f72a1 134 Gene3D G3DSA:3.30.1810.10 1 127 9.7E-54 T 10-03-2017 IPR009833 Uncharacterised protein DUF1398 RG49_RS04910 900cd4841f32617ff6290456e98f72a1 134 ProDom PD021249 YDFO YCGX ENVELOPE CYTOPLASMIC STY1988 CP-933X ECS1626 YBCV PROPHAGE 1 127 1.0E-71 T 10-03-2017 IPR009833 Uncharacterised protein DUF1398 RG49_RS10705 11a55626eb3def37068546cffa045721 160 SUPERFAMILY SSF141452 6 158 3.4E-32 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS10705 11a55626eb3def37068546cffa045721 160 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 157 5.6E-61 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS10705 11a55626eb3def37068546cffa045721 160 Gene3D G3DSA:2.30.110.20 1 154 1.9E-21 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS10705 11a55626eb3def37068546cffa045721 160 Pfam PF05638 Type VI secretion system effector, Hcp 22 144 6.6E-23 T 10-03-2017 IPR008514 Type VI secretion system effector, Hcp RG49_RS02905 69b1fb4d2afbbf4b253bc1f265e81454 298 SUPERFAMILY SSF161098 88 274 1.01E-25 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS02905 69b1fb4d2afbbf4b253bc1f265e81454 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 292 1.2E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS02905 69b1fb4d2afbbf4b253bc1f265e81454 298 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 70 3.9E-7 T 10-03-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain RG49_RS02905 69b1fb4d2afbbf4b253bc1f265e81454 298 Gene3D G3DSA:1.10.3720.10 86 291 3.5E-26 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS15290 344b956d357f7ff9840c2cc3a9e83607 367 TIGRFAM TIGR02380 ECA_wecA: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 8 351 6.3E-174 T 10-03-2017 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530 RG49_RS15290 344b956d357f7ff9840c2cc3a9e83607 367 Hamap MF_02030 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase [wecA]. 9 353 28.244 T 10-03-2017 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530 RG49_RS15290 344b956d357f7ff9840c2cc3a9e83607 367 Pfam PF00953 Glycosyl transferase family 4 76 232 4.8E-28 T 10-03-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 RG49_RS07810 83b737ffb679080aa9c0d56ed58ff728 155 Gene3D G3DSA:3.40.390.30 12 153 7.2E-52 T 10-03-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 RG49_RS07810 83b737ffb679080aa9c0d56ed58ff728 155 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 148 24.576 T 10-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 RG49_RS07810 83b737ffb679080aa9c0d56ed58ff728 155 Pfam PF02130 Uncharacterized protein family UPF0054 20 142 3.0E-39 T 10-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 RG49_RS07810 83b737ffb679080aa9c0d56ed58ff728 155 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 144 2.8E-37 T 10-03-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 RG49_RS07810 83b737ffb679080aa9c0d56ed58ff728 155 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 114 124 - T 10-03-2017 IPR020549 Endoribonuclease YbeY, conserved site RG49_RS07810 83b737ffb679080aa9c0d56ed58ff728 155 SUPERFAMILY SSF55486 3 151 2.03E-50 T 10-03-2017 RG49_RS13070 4d97bfd666acb755eacdd754110de020 445 SUPERFAMILY SSF53187 340 416 3.77E-53 T 10-03-2017 RG49_RS13070 4d97bfd666acb755eacdd754110de020 445 SUPERFAMILY SSF53187 192 288 3.77E-53 T 10-03-2017 RG49_RS13070 4d97bfd666acb755eacdd754110de020 445 SMART SM00646 254 413 4.6E-76 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS13070 4d97bfd666acb755eacdd754110de020 445 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 194 413 1.2E-48 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS13070 4d97bfd666acb755eacdd754110de020 445 Gene3D G3DSA:3.40.630.40 192 289 9.1E-59 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS13070 4d97bfd666acb755eacdd754110de020 445 Gene3D G3DSA:3.40.630.40 341 416 9.1E-59 T 10-03-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 RG49_RS17890 8d6026b6d86adee3567a335247e6539d 95 Hamap MF_01564 Protein TusB [tusB]. 1 95 31.158 T 10-03-2017 IPR023526 Sulphur relay, TusB GO:0002143|GO:0005737 RG49_RS17890 8d6026b6d86adee3567a335247e6539d 95 Gene3D G3DSA:3.40.1260.10 1 94 1.1E-35 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS17890 8d6026b6d86adee3567a335247e6539d 95 SUPERFAMILY SSF75169 1 95 1.41E-32 T 10-03-2017 IPR027396 DsrEFH-like RG49_RS17890 8d6026b6d86adee3567a335247e6539d 95 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 2 95 7.7E-34 T 10-03-2017 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 RG49_RS17890 8d6026b6d86adee3567a335247e6539d 95 Pfam PF04077 DsrH like protein 7 91 2.1E-30 T 10-03-2017 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 RG49_RS00990 baa4308cec92c44ae312c56d9e35f7bc 119 SUPERFAMILY SSF51197 1 106 1.0E-34 T 10-03-2017 RG49_RS00990 baa4308cec92c44ae312c56d9e35f7bc 119 Gene3D G3DSA:2.60.120.10 1 117 3.2E-45 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS00990 baa4308cec92c44ae312c56d9e35f7bc 119 Pfam PF09313 Domain of unknown function (DUF1971) 12 96 8.0E-24 T 10-03-2017 IPR015392 Domain of unknown function DUF1971 RG49_RS00990 baa4308cec92c44ae312c56d9e35f7bc 119 PIRSF PIRSF020632 1 119 3.8E-57 T 10-03-2017 IPR014510 Tellurite resistance predicted, YeaR RG49_RS21000 de932e898f4776101ae5b563fce85d5a 76 Gene3D G3DSA:2.30.30.100 21 76 7.1E-34 T 10-03-2017 RG49_RS21000 de932e898f4776101ae5b563fce85d5a 76 SUPERFAMILY SSF50182 24 74 5.07E-20 T 10-03-2017 IPR010920 LSM domain RG49_RS21000 de932e898f4776101ae5b563fce85d5a 76 Pfam PF06004 Bacterial protein of unknown function (DUF903) 25 73 2.1E-25 T 10-03-2017 IPR010305 Protein of unknown function DUF903 RG49_RS21270 a722e306873e09442010ff091331e4ce 178 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 12 169 8.8E-38 T 10-03-2017 IPR013382 CRISPR-associated protein Cse2 RG49_RS21270 a722e306873e09442010ff091331e4ce 178 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 25 167 2.0E-21 T 10-03-2017 IPR013382 CRISPR-associated protein Cse2 RG49_RS16330 f6ce7337713a898aa334649ea7733218 319 SUPERFAMILY SSF88713 24 238 1.67E-71 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS16330 f6ce7337713a898aa334649ea7733218 319 Gene3D G3DSA:3.20.20.370 12 248 6.0E-109 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS16330 f6ce7337713a898aa334649ea7733218 319 Pfam PF04748 Divergent polysaccharide deacetylase 28 238 4.9E-74 T 10-03-2017 IPR006837 Divergent polysaccharide deacetylase RG49_RS06230 39abe98e4946779c8b765fa528e44006 196 Pfam PF02525 Flavodoxin-like fold 5 181 2.8E-39 T 10-03-2017 IPR003680 Flavodoxin-like fold RG49_RS06230 39abe98e4946779c8b765fa528e44006 196 Gene3D G3DSA:3.40.50.360 4 192 3.8E-42 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS06230 39abe98e4946779c8b765fa528e44006 196 SUPERFAMILY SSF52218 5 189 5.12E-45 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS07365 95d6b9a5e688947f79739e307a1680a9 134 Pfam PF03061 Thioesterase superfamily 20 103 2.1E-18 T 10-03-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 RG49_RS07365 95d6b9a5e688947f79739e307a1680a9 134 PIRSF PIRSF003230 1 134 1.5E-50 T 10-03-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 RG49_RS07365 95d6b9a5e688947f79739e307a1680a9 134 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 125 1.2E-50 T 10-03-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 RG49_RS07365 95d6b9a5e688947f79739e307a1680a9 134 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 6 130 1.4E-51 T 10-03-2017 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 RG49_RS07365 95d6b9a5e688947f79739e307a1680a9 134 Gene3D G3DSA:3.10.129.10 4 133 1.0E-48 T 10-03-2017 IPR029069 HotDog domain RG49_RS07365 95d6b9a5e688947f79739e307a1680a9 134 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 11 28 - T 10-03-2017 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 RG49_RS07365 95d6b9a5e688947f79739e307a1680a9 134 SUPERFAMILY SSF54637 4 133 2.24E-40 T 10-03-2017 IPR029069 HotDog domain RG49_RS25150 d326d5f2106744488cabcaf962b95a70 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 10-03-2017 IPR001455 TusA-like domain RG49_RS25150 d326d5f2106744488cabcaf962b95a70 75 Gene3D G3DSA:3.30.110.40 3 74 1.8E-22 T 10-03-2017 IPR001455 TusA-like domain RG49_RS25150 d326d5f2106744488cabcaf962b95a70 75 SUPERFAMILY SSF64307 3 74 1.18E-20 T 10-03-2017 IPR001455 TusA-like domain RG49_RS25150 d326d5f2106744488cabcaf962b95a70 75 Pfam PF01206 Sulfurtransferase TusA 4 74 5.8E-18 T 10-03-2017 IPR001455 TusA-like domain RG49_RS25030 748d64699cd917dc52afe6f0e75d6442 266 Pfam PF00535 Glycosyl transferase family 2 6 140 1.9E-31 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS25030 748d64699cd917dc52afe6f0e75d6442 266 Gene3D G3DSA:3.90.550.10 4 233 2.0E-51 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS25030 748d64699cd917dc52afe6f0e75d6442 266 SUPERFAMILY SSF53448 4 219 7.74E-52 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS05340 46aeaec8f464c962863c5da2c65b296e 81 Pfam PF06183 DinI-like family 14 78 2.3E-28 T 10-03-2017 IPR010391 DNA damage-inducible protein DinI-like RG49_RS05340 46aeaec8f464c962863c5da2c65b296e 81 SUPERFAMILY SSF54857 1 80 5.75E-29 T 10-03-2017 IPR010391 DNA damage-inducible protein DinI-like RG49_RS05340 46aeaec8f464c962863c5da2c65b296e 81 Gene3D G3DSA:3.30.910.10 1 80 2.9E-36 T 10-03-2017 IPR010391 DNA damage-inducible protein DinI-like RG49_RS23995 01846cf6b1c4d6c0fcc60600392ffdd4 440 TIGRFAM TIGR00366 TIGR00366: TIGR00366 family protein 4 428 4.7E-226 T 10-03-2017 IPR006161 Conserved hypothetical protein CHP00336 RG49_RS23995 01846cf6b1c4d6c0fcc60600392ffdd4 440 Pfam PF02667 Short chain fatty acid transporter 1 440 3.4E-231 T 10-03-2017 IPR006160 Short chain fatty acid transporter AtoE RG49_RS15100 04162306fdb10f87b035e560bcf0f239 138 ProDom PD084423 MEMBRANE INNER YIGG STY3605 TRANSMEMBRANE 13 138 2.0E-54 T 10-03-2017 IPR020332 Uncharacterised protein family, inner membrane YigG RG49_RS19350 c804fac8730d985af23818944fad05dc 468 Gene3D G3DSA:3.90.1150.10 349 461 4.0E-35 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS19350 c804fac8730d985af23818944fad05dc 468 Gene3D G3DSA:3.40.640.10 109 348 1.6E-92 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS19350 c804fac8730d985af23818944fad05dc 468 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 277 314 - T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS19350 c804fac8730d985af23818944fad05dc 468 SUPERFAMILY SSF53383 79 459 2.92E-120 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS19350 c804fac8730d985af23818944fad05dc 468 Pfam PF00202 Aminotransferase class-III 83 458 8.6E-105 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS19350 c804fac8730d985af23818944fad05dc 468 Hamap MF_01276 Putrescine aminotransferase [patA]. 10 468 90.869 T 10-03-2017 IPR017747 Putrescine aminotransferase GO:0009447|GO:0030170|GO:0033094 KEGG: 00330+2.6.1.82|MetaCyc: PWY-2|MetaCyc: PWY-6440 RG49_RS19350 c804fac8730d985af23818944fad05dc 468 TIGRFAM TIGR03372 putres_am_tran: putrescine aminotransferase 17 458 2.5E-295 T 10-03-2017 IPR017747 Putrescine aminotransferase GO:0009447|GO:0030170|GO:0033094 KEGG: 00330+2.6.1.82|MetaCyc: PWY-2|MetaCyc: PWY-6440 RG49_RS12285 b1fa22726db11c1d5116c8e7695db43f 54 Pfam PF06568 Domain of unknown function (DUF1127) 18 54 1.2E-13 T 10-03-2017 IPR009506 Protein of unknown function DUF1127 RG49_RS12410 2561a628215166917a30045b1b2e650a 167 Gene3D G3DSA:2.60.40.1090 27 166 4.5E-24 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS12410 2561a628215166917a30045b1b2e650a 167 SUPERFAMILY SSF49401 27 166 9.44E-25 T 10-03-2017 IPR008966 Adhesion domain RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 SUPERFAMILY SSF54197 179 345 2.38E-59 T 10-03-2017 IPR011146 HIT-like domain GO:0003824 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 Gene3D G3DSA:3.30.428.10 45 175 1.5E-57 T 10-03-2017 IPR011146 HIT-like domain GO:0003824 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 183 345 7.3E-73 T 10-03-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 151 168 - T 10-03-2017 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 1 347 1.3E-215 T 10-03-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 3 176 5.2E-70 T 10-03-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 SUPERFAMILY SSF54197 3 177 5.27E-73 T 10-03-2017 IPR011146 HIT-like domain GO:0003824 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 PIRSF PIRSF000808 1 341 2.5E-129 T 10-03-2017 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 RG49_RS07250 325cb7c5269d14c0d53593362b5dfad8 348 Gene3D G3DSA:3.30.428.10 176 345 2.3E-80 T 10-03-2017 IPR011146 HIT-like domain GO:0003824 RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 SUPERFAMILY SSF46785 2 106 2.61E-26 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 SUPERFAMILY SSF50331 200 259 1.74E-14 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 Pfam PF03459 TOBE domain 125 187 6.7E-12 T 10-03-2017 IPR005116 Transport-associated OB, type 1 RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 Pfam PF03459 TOBE domain 199 257 9.0E-14 T 10-03-2017 IPR005116 Transport-associated OB, type 1 RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 16 113 4.2E-41 T 10-03-2017 IPR003725 Molybdenum-binding protein ModE, N-terminal RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 Gene3D G3DSA:2.40.50.100 120 184 7.9E-32 T 10-03-2017 RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 SUPERFAMILY SSF50331 123 192 4.62E-17 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 Gene3D G3DSA:2.40.50.100 185 252 4.9E-23 T 10-03-2017 RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 Gene3D G3DSA:1.10.10.10 1 119 3.6E-42 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 83 1.2E-13 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 123 192 2.7E-28 T 10-03-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 RG49_RS07235 0b06eab3efde23ce54d4f3d54d8c0318 262 PIRSF PIRSF005763 1 262 4.3E-101 T 10-03-2017 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 RG49_RS04760 e48a5bef1106a8f9761d1c9519a53ac7 219 Gene3D G3DSA:3.90.850.10 14 218 9.7E-80 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS04760 e48a5bef1106a8f9761d1c9519a53ac7 219 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 18 210 1.6E-53 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS04760 e48a5bef1106a8f9761d1c9519a53ac7 219 SUPERFAMILY SSF56529 11 213 9.03E-71 T 10-03-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 RG49_RS08370 e4554e1e241c325ccd0866bb59d28bf7 378 Pfam PF01609 Transposase DDE domain 102 343 1.5E-31 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS08370 e4554e1e241c325ccd0866bb59d28bf7 378 Pfam PF13808 DDE_Tnp_1-associated 7 94 5.6E-33 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS24990 8f4d6203f6b6bfa028b8ca41d8ad49a9 297 SUPERFAMILY SSF53448 2 283 5.86E-58 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS24990 8f4d6203f6b6bfa028b8ca41d8ad49a9 297 Gene3D G3DSA:3.90.550.10 4 276 5.3E-65 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS24990 8f4d6203f6b6bfa028b8ca41d8ad49a9 297 Pfam PF00483 Nucleotidyl transferase 5 274 2.7E-21 T 10-03-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 RG49_RS24990 8f4d6203f6b6bfa028b8ca41d8ad49a9 297 TIGRFAM TIGR01105 galF: regulatory protein GalF 1 297 5.1E-208 T 10-03-2017 IPR005774 UTP-glucose pyrophosphorylase, regulatory subunit GO:0006011|GO:0030234 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 RG49_RS23065 dbff7c9b90f1e95a740c4485693de230 253 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 9 249 29.292 T 10-03-2017 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 RG49_RS23065 dbff7c9b90f1e95a740c4485693de230 253 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 15 231 3.3E-44 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 331 2.0E-106 T 10-03-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 376 398 3.9E-6 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 619 633 3.9E-6 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 SUPERFAMILY SSF51971 333 519 8.95E-42 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 Gene3D G3DSA:3.20.20.70 3 360 4.7E-120 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 SUPERFAMILY SSF51905 467 627 3.45E-27 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 Gene3D G3DSA:3.50.50.60 361 463 4.0E-25 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 Gene3D G3DSA:3.50.50.60 469 625 1.0E-52 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 497 515 7.9E-12 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 396 7.9E-12 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 618 634 7.9E-12 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 SUPERFAMILY SSF51395 1 362 4.51E-109 T 10-03-2017 RG49_RS19305 2afeca3cbb17b27e3b293646b2d8ece8 672 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 376 635 9.8E-25 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS12525 220776468fdb92d211ec8cc9635192d2 154 SMART SM00530 12 67 2.7E-12 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS12525 220776468fdb92d211ec8cc9635192d2 154 SUPERFAMILY SSF47413 5 73 1.66E-17 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS12525 220776468fdb92d211ec8cc9635192d2 154 Pfam PF13560 Helix-turn-helix domain 8 64 6.6E-15 T 10-03-2017 RG49_RS12525 220776468fdb92d211ec8cc9635192d2 154 Gene3D G3DSA:1.10.260.40 2 76 2.7E-21 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS17400 ebb53170606a348b7e6b3f6c96c87a3b 197 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 191 4.5E-31 T 10-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 RG49_RS17400 ebb53170606a348b7e6b3f6c96c87a3b 197 Pfam PF01914 MarC family integral membrane protein 1 195 2.6E-65 T 10-03-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 RG49_RS21795 cd2633b42264cd3e68fc62dfcdb43b3f 325 SUPERFAMILY SSF51197 16 321 1.6E-93 T 10-03-2017 RG49_RS21795 cd2633b42264cd3e68fc62dfcdb43b3f 325 Gene3D G3DSA:3.60.130.10 16 325 5.3E-136 T 10-03-2017 RG49_RS21795 cd2633b42264cd3e68fc62dfcdb43b3f 325 Pfam PF08943 CsiD 21 314 7.2E-149 T 10-03-2017 IPR015038 Uncharacterised protein family CsiD GO:0005506 RG49_RS21795 cd2633b42264cd3e68fc62dfcdb43b3f 325 Hamap MF_01083 Protein CsiD [csiD]. 1 325 78.049 T 10-03-2017 IPR015038 Uncharacterised protein family CsiD GO:0005506 RG49_RS21795 cd2633b42264cd3e68fc62dfcdb43b3f 325 ProDom PD135861 METAL-BINDING IRON CSID GAB CYTOPLASMIC 3D-STRUCTURE HOMOLOG DIRECT SEQUENCING 16 314 3.0E-161 T 10-03-2017 IPR015038 Uncharacterised protein family CsiD GO:0005506 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 Pfam PF13533 Biotin-lipoyl like 48 94 1.3E-10 T 10-03-2017 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 SUPERFAMILY SSF111369 189 286 3.53E-5 T 10-03-2017 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 SUPERFAMILY SSF111369 41 112 3.01E-8 T 10-03-2017 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 Pfam PF13437 HlyD family secretion protein 214 318 5.4E-13 T 10-03-2017 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 Gene3D G3DSA:2.40.50.100 47 80 1.8E-13 T 10-03-2017 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 Gene3D G3DSA:2.40.50.100 211 244 1.8E-13 T 10-03-2017 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 327 342 4.1E-6 T 10-03-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 RG49_RS17130 b95a98b02319bf14363ba7c8681a7a2e 355 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 58 78 4.1E-6 T 10-03-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 RG49_RS05595 23ee0d4a70a2d6d1fd499146cb3c5cc5 375 SUPERFAMILY SSF49503 16 116 5.63E-6 T 10-03-2017 IPR008972 Cupredoxin RG49_RS05595 23ee0d4a70a2d6d1fd499146cb3c5cc5 375 Pfam PF13473 Cupredoxin-like domain 13 115 6.0E-25 T 10-03-2017 IPR028096 EfeO-type cupredoxin-like domain RG49_RS05595 23ee0d4a70a2d6d1fd499146cb3c5cc5 375 Pfam PF09375 Imelysin 135 368 5.2E-44 T 10-03-2017 RG49_RS05595 23ee0d4a70a2d6d1fd499146cb3c5cc5 375 Gene3D G3DSA:2.60.40.420 15 116 1.4E-6 T 10-03-2017 IPR008972 Cupredoxin RG49_RS13410 33dac07f14ab09bb97c3d56fc3ed9045 288 Pfam PF13990 YjcZ-like protein 21 283 1.5E-132 T 10-03-2017 IPR025599 YjcZ-like protein RG49_RS20115 9e3aa2b894766832b7c2e5f7eb29e652 197 Pfam PF01725 Ham1 family 4 191 1.4E-56 T 10-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 RG49_RS20115 9e3aa2b894766832b7c2e5f7eb29e652 197 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 194 1.0E-72 T 10-03-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 RG49_RS20115 9e3aa2b894766832b7c2e5f7eb29e652 197 Gene3D G3DSA:3.90.950.10 1 195 2.1E-84 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS20115 9e3aa2b894766832b7c2e5f7eb29e652 197 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 196 51.918 T 10-03-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 RG49_RS20115 9e3aa2b894766832b7c2e5f7eb29e652 197 SUPERFAMILY SSF52972 1 195 1.18E-75 T 10-03-2017 IPR029001 Inosine triphosphate pyrophosphatase-like RG49_RS17525 7a667cdb18b6a36eb976d27c4073c7c4 773 Pfam PF07664 Ferrous iron transport protein B C terminus 455 507 1.9E-20 T 10-03-2017 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 RG49_RS17525 7a667cdb18b6a36eb976d27c4073c7c4 773 SUPERFAMILY SSF52540 4 170 2.31E-40 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17525 7a667cdb18b6a36eb976d27c4073c7c4 773 Pfam PF07670 Nucleoside recognition 353 443 6.1E-13 T 10-03-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 RG49_RS17525 7a667cdb18b6a36eb976d27c4073c7c4 773 Pfam PF07670 Nucleoside recognition 512 689 8.8E-37 T 10-03-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 RG49_RS17525 7a667cdb18b6a36eb976d27c4073c7c4 773 Gene3D G3DSA:3.40.50.300 3 171 7.7E-36 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS17525 7a667cdb18b6a36eb976d27c4073c7c4 773 Pfam PF02421 Ferrous iron transport protein B 5 162 4.3E-64 T 10-03-2017 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 RG49_RS17525 7a667cdb18b6a36eb976d27c4073c7c4 773 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 687 4.4E-255 T 10-03-2017 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 RG49_RS12660 3691bc3a112b689e4110d399f97fdaaf 44 PIRSF PIRSF003249 1 44 5.9E-36 T 10-03-2017 IPR012602 PyrBI operon leader peptide GO:0019856 RG49_RS12660 3691bc3a112b689e4110d399f97fdaaf 44 Pfam PF08052 PyrBI operon leader peptide 1 44 2.2E-34 T 10-03-2017 IPR012602 PyrBI operon leader peptide GO:0019856 RG49_RS20660 b393aa793b798fafeaa0c74aec97ea31 97 Pfam PF04741 InvH outer membrane lipoprotein 41 95 9.1E-8 T 10-03-2017 IPR006830 InvH outer membrane lipoprotein GO:0009405 RG49_RS20660 b393aa793b798fafeaa0c74aec97ea31 97 ProDom PD004896 INVH LIPOPROTEIN MEMBRANE PALMITATE ADHERANCE/INVASION OUTER PRECURSOR INVASION VIRULENCE SIGNAL 46 95 5.0E-5 T 10-03-2017 IPR006830 InvH outer membrane lipoprotein GO:0009405 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 Pfam PF01266 FAD dependent oxidoreductase 267 632 4.8E-47 T 10-03-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 Gene3D G3DSA:3.40.50.150 11 248 4.3E-106 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 7 657 28.479 T 10-03-2017 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 SUPERFAMILY SSF51905 267 545 1.55E-28 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 267 662 8.4E-157 T 10-03-2017 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 Gene3D G3DSA:3.50.50.60 396 477 1.6E-24 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 Gene3D G3DSA:3.50.50.60 263 344 1.6E-24 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 Gene3D G3DSA:3.50.50.60 571 645 1.6E-24 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS23455 e9e9869d99b48b3ad5db397b9e6a89ba 668 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 118 244 3.6E-51 T 10-03-2017 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 RG49_RS12165 bac18432808bba911238b9801217304f 323 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 306 2.8E-66 T 10-03-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 RG49_RS12165 bac18432808bba911238b9801217304f 323 PIRSF PIRSF006470 1 323 1.8E-66 T 10-03-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 RG49_RS12165 bac18432808bba911238b9801217304f 323 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 284 2.2E-53 T 10-03-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 RG49_RS12165 bac18432808bba911238b9801217304f 323 SUPERFAMILY SSF53850 131 212 3.36E-5 T 10-03-2017 RG49_RS23765 d820a3489decc11ba033fcd84fa53181 431 Hamap MF_01935 Isochorismate synthase MenF [menF]. 7 430 42.251 T 10-03-2017 RG49_RS23765 d820a3489decc11ba033fcd84fa53181 431 SUPERFAMILY SSF56322 12 428 1.14E-104 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS23765 d820a3489decc11ba033fcd84fa53181 431 Gene3D G3DSA:3.60.120.10 38 429 3.2E-80 T 10-03-2017 IPR005801 ADC synthase GO:0009058 RG49_RS23765 d820a3489decc11ba033fcd84fa53181 431 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 93 427 1.3E-108 T 10-03-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 RG49_RS23765 d820a3489decc11ba033fcd84fa53181 431 Pfam PF00425 chorismate binding enzyme 169 420 7.7E-63 T 10-03-2017 IPR015890 Chorismate-utilising enzyme, C-terminal RG49_RS16070 90a0e40c301897283d3379201da42c77 161 SUPERFAMILY SSF50249 5 161 2.12E-55 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16070 90a0e40c301897283d3379201da42c77 161 PIRSF PIRSF002070 2 154 1.2E-39 T 10-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 RG49_RS16070 90a0e40c301897283d3379201da42c77 161 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 161 1.3E-54 T 10-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 RG49_RS16070 90a0e40c301897283d3379201da42c77 161 Pfam PF00436 Single-strand binding protein family 6 112 5.0E-40 T 10-03-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 RG49_RS16070 90a0e40c301897283d3379201da42c77 161 Gene3D G3DSA:2.40.50.140 4 161 2.2E-58 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16070 90a0e40c301897283d3379201da42c77 161 Hamap MF_00984 Single-stranded DNA-binding protein. 6 117 38.192 T 10-03-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 RG49_RS13385 feffc6fef72fac3f6a2b4e7b532b4bbb 547 Gene3D G3DSA:3.40.720.10 239 532 5.0E-16 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS13385 feffc6fef72fac3f6a2b4e7b532b4bbb 547 SUPERFAMILY SSF53649 239 531 6.17E-21 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS13385 feffc6fef72fac3f6a2b4e7b532b4bbb 547 Pfam PF08019 Domain of unknown function (DUF1705) 59 209 2.6E-43 T 10-03-2017 IPR012549 Domain of unknown function DUF1705 GO:0016021 RG49_RS13385 feffc6fef72fac3f6a2b4e7b532b4bbb 547 Pfam PF00884 Sulfatase 238 527 4.9E-54 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS11780 d3b101a32afcf089880b516e367017f6 388 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 7 380 8.6E-200 T 10-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 RG49_RS11780 d3b101a32afcf089880b516e367017f6 388 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 4 386 24.059 T 10-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 RG49_RS11780 d3b101a32afcf089880b516e367017f6 388 Pfam PF06965 Na+/H+ antiporter 1 6 380 3.3E-152 T 10-03-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 RG49_RS11780 d3b101a32afcf089880b516e367017f6 388 Gene3D G3DSA:1.20.1530.10 2 385 3.9E-161 T 10-03-2017 IPR023171 Na/H antiporter domain RG49_RS09950 c40dc163c7d9374e41d275422aeeea3b 317 Gene3D G3DSA:3.40.830.10 7 187 3.5E-86 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09950 c40dc163c7d9374e41d275422aeeea3b 317 Gene3D G3DSA:3.40.830.10 232 315 3.5E-86 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09950 c40dc163c7d9374e41d275422aeeea3b 317 SUPERFAMILY SSF53213 5 185 2.22E-71 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09950 c40dc163c7d9374e41d275422aeeea3b 317 SUPERFAMILY SSF53213 230 313 2.22E-71 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09950 c40dc163c7d9374e41d275422aeeea3b 317 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 309 4.6E-84 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09950 c40dc163c7d9374e41d275422aeeea3b 317 Hamap MF_01653 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase [mhpB]. 1 316 54.456 T 10-03-2017 IPR023789 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase GO:0005506|GO:0019439|GO:0047070|GO:0055114 KEGG: 00360+1.13.11.16|MetaCyc: PWY-6690 RG49_RS06425 ccfd3f57e7436946f6800bbd1bef0075 276 SUPERFAMILY SSF55846 24 194 1.7E-52 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS06425 ccfd3f57e7436946f6800bbd1bef0075 276 Gene3D G3DSA:3.40.80.10 40 197 9.3E-57 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS06425 ccfd3f57e7436946f6800bbd1bef0075 276 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 43 179 5.3E-20 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS06425 ccfd3f57e7436946f6800bbd1bef0075 276 SUPERFAMILY SSF47090 198 273 2.28E-21 T 10-03-2017 IPR002477 Peptidoglycan binding-like RG49_RS06425 ccfd3f57e7436946f6800bbd1bef0075 276 SMART SM00644 32 178 8.0E-43 T 10-03-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 RG49_RS01505 06fae8bc6a882323282c58129bdf9b9e 277 Pfam PF03618 Kinase/pyrophosphorylase 9 267 4.7E-73 T 10-03-2017 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 RG49_RS01505 06fae8bc6a882323282c58129bdf9b9e 277 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 6 276 72.949 T 10-03-2017 IPR026530 Phosphoenolpyruvate synthase regulatory protein RG49_RS20675 3933e69548cb29fb07d926e3e469be9b 237 Pfam PF09480 Type III secretion system protein PrgH-EprH (PrgH) 5 235 1.7E-52 T 10-03-2017 IPR019029 Type III secretion system, PrgH/EprH-like GO:0016021 RG49_RS06100 679f9d441d38637cd2f65af2dc47cc11 182 Gene3D G3DSA:3.30.1380.10 67 182 4.1E-29 T 10-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 RG49_RS06100 679f9d441d38637cd2f65af2dc47cc11 182 Pfam PF05951 Bacterial protein of unknown function (DUF882) 34 182 1.2E-61 T 10-03-2017 IPR010275 Protein of unknown function DUF882 RG49_RS06100 679f9d441d38637cd2f65af2dc47cc11 182 SUPERFAMILY SSF55166 68 182 1.33E-31 T 10-03-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 RG49_RS11245 1c4eb8da7d0ef9335ecc32a9284914d4 288 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 81 94 - T 10-03-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 RG49_RS11245 1c4eb8da7d0ef9335ecc32a9284914d4 288 Gene3D G3DSA:3.40.50.150 57 284 1.3E-83 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS11245 1c4eb8da7d0ef9335ecc32a9284914d4 288 TIGRFAM TIGR00417 speE: spermidine synthase 7 278 1.9E-125 T 10-03-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 RG49_RS11245 1c4eb8da7d0ef9335ecc32a9284914d4 288 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 6 284 39.149 T 10-03-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 RG49_RS11245 1c4eb8da7d0ef9335ecc32a9284914d4 288 Gene3D G3DSA:2.30.140.10 7 56 2.7E-20 T 10-03-2017 RG49_RS11245 1c4eb8da7d0ef9335ecc32a9284914d4 288 SUPERFAMILY SSF53335 7 283 5.17E-89 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS11245 1c4eb8da7d0ef9335ecc32a9284914d4 288 Pfam PF01564 Spermine/spermidine synthase 7 239 1.8E-88 T 10-03-2017 RG49_RS08840 17cc13b4500106ffcd40e22a22b3dff7 32 Pfam PF07237 Protein of unknown function (DUF1428) 2 31 1.3E-9 T 10-03-2017 IPR009874 Protein of unknown function DUF1428 RG49_RS08840 17cc13b4500106ffcd40e22a22b3dff7 32 SUPERFAMILY SSF54909 1 31 1.5E-8 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS08840 17cc13b4500106ffcd40e22a22b3dff7 32 Gene3D G3DSA:3.30.70.900 1 31 3.9E-10 T 10-03-2017 RG49_RS18520 67388c685c9907204af0f852b1362933 154 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 153 3.2E-67 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS18520 67388c685c9907204af0f852b1362933 154 Gene3D G3DSA:2.60.120.370 1 152 2.9E-49 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS18520 67388c685c9907204af0f852b1362933 154 Pfam PF04074 Domain of unknown function (DUF386) 1 149 5.9E-41 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS18520 67388c685c9907204af0f852b1362933 154 SUPERFAMILY SSF51197 1 152 1.24E-43 T 10-03-2017 RG49_RS15820 1f6d6ee735a51e868b0b829f66343399 58 Gene3D G3DSA:3.90.110.10 1 57 3.8E-20 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS15820 1f6d6ee735a51e868b0b829f66343399 58 SUPERFAMILY SSF56327 1 57 3.97E-19 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS09270 e3852ace2e7d124aa9c7bd69f9301c40 222 SUPERFAMILY SSF51206 39 138 1.93E-6 T 10-03-2017 IPR018490 Cyclic nucleotide-binding-like RG49_RS09270 e3852ace2e7d124aa9c7bd69f9301c40 222 Pfam PF15977 Winged helix-turn-helix DNA binding 153 220 1.7E-29 T 10-03-2017 RG49_RS09270 e3852ace2e7d124aa9c7bd69f9301c40 222 Gene3D G3DSA:1.10.10.10 153 218 3.5E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS03685 ec745e9c8e1fc09f076300075fdcb957 667 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 59 506 2.0E-163 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS03685 ec745e9c8e1fc09f076300075fdcb957 667 ProSitePatterns PS01303 BCCT family of transporters signature. 323 332 - T 10-03-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 RG49_RS03685 ec745e9c8e1fc09f076300075fdcb957 667 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 21 506 1.7E-195 T 10-03-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 RG49_RS01760 b94787472c3d2d87a2e23da87b76ffa0 389 SUPERFAMILY SSF103473 6 379 2.49E-52 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01760 b94787472c3d2d87a2e23da87b76ffa0 389 Pfam PF07690 Major Facilitator Superfamily 10 342 4.4E-32 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS01760 b94787472c3d2d87a2e23da87b76ffa0 389 Gene3D G3DSA:1.20.1250.20 200 380 9.3E-12 T 10-03-2017 RG49_RS01760 b94787472c3d2d87a2e23da87b76ffa0 389 Gene3D G3DSA:1.20.1250.20 6 192 6.3E-24 T 10-03-2017 RG49_RS04100 5b86580b2e5935cabca91c91c0a12f7b 268 Gene3D G3DSA:3.40.50.300 3 251 1.9E-70 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04100 5b86580b2e5935cabca91c91c0a12f7b 268 Pfam PF00005 ABC transporter 31 178 1.8E-33 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS04100 5b86580b2e5935cabca91c91c0a12f7b 268 SUPERFAMILY SSF52540 5 251 2.51E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04100 5b86580b2e5935cabca91c91c0a12f7b 268 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS04100 5b86580b2e5935cabca91c91c0a12f7b 268 SMART SM00382 39 228 2.1E-15 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS07220 5d5ac211ab72e23e2d88dc3e1e0850a5 257 PIRSF PIRSF004846 1 257 1.5E-85 T 10-03-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 RG49_RS07220 5d5ac211ab72e23e2d88dc3e1e0850a5 257 Gene3D G3DSA:3.40.190.10 219 254 1.3E-17 T 10-03-2017 RG49_RS07220 5d5ac211ab72e23e2d88dc3e1e0850a5 257 Gene3D G3DSA:3.40.190.10 28 109 1.3E-17 T 10-03-2017 RG49_RS07220 5d5ac211ab72e23e2d88dc3e1e0850a5 257 Gene3D G3DSA:3.40.190.10 110 218 8.6E-45 T 10-03-2017 RG49_RS07220 5d5ac211ab72e23e2d88dc3e1e0850a5 257 SUPERFAMILY SSF53850 28 255 2.39E-71 T 10-03-2017 RG49_RS07220 5d5ac211ab72e23e2d88dc3e1e0850a5 257 Pfam PF13531 Bacterial extracellular solute-binding protein 29 254 4.8E-51 T 10-03-2017 RG49_RS07220 5d5ac211ab72e23e2d88dc3e1e0850a5 257 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 34 253 4.1E-89 T 10-03-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 RG49_RS00450 7f806aa4d5cc9a3a755ef1ace640419b 116 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 1 104 28.278 T 10-03-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 RG49_RS00450 7f806aa4d5cc9a3a755ef1ace640419b 116 SUPERFAMILY SSF63592 1 98 1.23E-39 T 10-03-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 RG49_RS00450 7f806aa4d5cc9a3a755ef1ace640419b 116 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 9 98 5.0E-47 T 10-03-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 RG49_RS00450 7f806aa4d5cc9a3a755ef1ace640419b 116 Pfam PF05247 Flagellar transcriptional activator (FlhD) 1 100 4.4E-41 T 10-03-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 RG49_RS12310 14e3684debc85039c8a32443cb1659a2 426 Pfam PF04286 Protein of unknown function (DUF445) 44 417 4.5E-108 T 10-03-2017 IPR007383 Protein of unknown function DUF445 RG49_RS03335 4a202be779316d3b41f2934848aa49c4 58 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1 58 6.8E-15 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03335 4a202be779316d3b41f2934848aa49c4 58 SUPERFAMILY SSF51735 1 58 4.56E-14 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03335 4a202be779316d3b41f2934848aa49c4 58 Gene3D G3DSA:3.40.50.720 1 58 5.2E-16 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03335 4a202be779316d3b41f2934848aa49c4 58 SMART SM00846 1 57 0.0014 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03330 933664ba163cff529826cabe41fd20ed 38 Gene3D G3DSA:3.40.50.720 2 36 2.5E-11 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03330 933664ba163cff529826cabe41fd20ed 38 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 36 7.4E-10 T 10-03-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03330 933664ba163cff529826cabe41fd20ed 38 SUPERFAMILY SSF51735 1 36 4.81E-12 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 6 353 1.8E-141 T 10-03-2017 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 SUPERFAMILY SSF160544 243 350 6.28E-41 T 10-03-2017 IPR029025 Type III secretion system substrate exporter, C-terminal RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 Gene3D G3DSA:3.40.1690.10 217 354 7.5E-64 T 10-03-2017 IPR029025 Type III secretion system substrate exporter, C-terminal RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 207 225 1.1E-43 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 271 286 1.1E-43 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 227 244 1.1E-43 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 301 322 1.1E-43 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 9 31 1.1E-43 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS00510 64df6f77593629d1d7f66755863c5f66 382 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 346 3.7E-124 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 SUPERFAMILY SSF55120 69 234 9.87E-43 T 10-03-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 SMART SM00363 3 74 4.3E-11 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 107 121 - T 10-03-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 Gene3D G3DSA:3.10.290.10 3 62 2.5E-15 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 233 3.4E-64 T 10-03-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 Pfam PF00849 RNA pseudouridylate synthase 69 199 1.6E-15 T 10-03-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 Pfam PF01479 S4 domain 4 43 3.9E-12 T 10-03-2017 IPR002942 RNA-binding S4 domain GO:0003723 RG49_RS04240 2d06d19be4e854443c9185e797f09654 291 SUPERFAMILY SSF55174 5 98 5.3E-14 T 10-03-2017 RG49_RS21350 0856dc608b1d4b7dbbc35dee969c97f8 253 Gene3D G3DSA:3.40.1210.10 1 246 7.1E-85 T 10-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 RG49_RS21350 0856dc608b1d4b7dbbc35dee969c97f8 253 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 249 40.359 T 10-03-2017 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 RG49_RS21350 0856dc608b1d4b7dbbc35dee969c97f8 253 SUPERFAMILY SSF64167 1 246 3.4E-83 T 10-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 RG49_RS21350 0856dc608b1d4b7dbbc35dee969c97f8 253 Pfam PF01975 Survival protein SurE 3 180 4.9E-56 T 10-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 RG49_RS21350 0856dc608b1d4b7dbbc35dee969c97f8 253 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 2.3E-80 T 10-03-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 RG49_RS00710 0bc4e678860c87c46670c6523ea2c1cd 219 Gene3D G3DSA:1.10.3680.10 66 212 2.2E-14 T 10-03-2017 IPR029024 TerB-like RG49_RS00710 0bc4e678860c87c46670c6523ea2c1cd 219 SUPERFAMILY SSF158682 88 212 2.09E-18 T 10-03-2017 IPR029024 TerB-like RG49_RS00710 0bc4e678860c87c46670c6523ea2c1cd 219 Pfam PF04391 Protein of unknown function (DUF533) 33 209 7.7E-50 T 10-03-2017 IPR007486 Inner membrane protein YebE RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 142 173 - T 10-03-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 Pfam PF02056 Family 4 glycosyl hydrolase 6 188 2.6E-81 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 SUPERFAMILY SSF51735 5 171 1.61E-53 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 198 421 4.3E-63 T 10-03-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 194 206 6.4E-42 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 113 133 6.4E-42 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 142 159 6.4E-42 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 6.4E-42 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 168 179 6.4E-42 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 6.4E-42 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 75 91 6.4E-42 T 10-03-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 Gene3D G3DSA:3.40.50.720 3 168 2.0E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 Gene3D G3DSA:3.90.110.10 171 449 5.7E-85 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS13355 6d505dc174f4ca3d2659b5f22e58656d 451 SUPERFAMILY SSF56327 172 449 7.68E-75 T 10-03-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 RG49_RS13285 d48a8b724fd6b65b4e3bf3f71553dd2e 485 SUPERFAMILY SSF103473 4 290 1.83E-27 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS13285 d48a8b724fd6b65b4e3bf3f71553dd2e 485 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 64 88 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS13285 d48a8b724fd6b65b4e3bf3f71553dd2e 485 Gene3D G3DSA:1.20.1250.20 18 185 1.2E-19 T 10-03-2017 RG49_RS13285 d48a8b724fd6b65b4e3bf3f71553dd2e 485 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 139 151 - T 10-03-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 RG49_RS13285 d48a8b724fd6b65b4e3bf3f71553dd2e 485 SUPERFAMILY SSF103473 213 472 1.7E-5 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS13285 d48a8b724fd6b65b4e3bf3f71553dd2e 485 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 6 457 5.0E-80 T 10-03-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 RG49_RS13285 d48a8b724fd6b65b4e3bf3f71553dd2e 485 Pfam PF00854 POT family 76 437 7.8E-91 T 10-03-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 679 720 3.5E-9 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 618 649 6.0E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 764 802 2.7E-6 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 725 761 4.0E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 934 963 0.002 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 553 592 2.9E-7 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 976 1014 7.9E-9 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 995 1022 7.7E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 869 909 1.5E-5 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1259 1290 1.6E-4 T 10-03-2017 IPR006530 YD repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1410 1470 2.3E-19 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 Pfam PF05488 PAAR motif 264 310 1.3E-9 T 10-03-2017 IPR008727 PAAR motif RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 Pfam PF05593 RHS Repeat 976 1009 6.5E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 Pfam PF05593 RHS Repeat 618 653 1.2E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 Pfam PF05593 RHS Repeat 869 904 2.1E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 Pfam PF05593 RHS Repeat 995 1026 1.4E-4 T 10-03-2017 IPR031325 RHS repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 Pfam PF05593 RHS Repeat 679 716 7.0E-8 T 10-03-2017 IPR031325 RHS repeat RG49_RS08345 fb4a8da788a12fa0d30e415bcd7863fc 1505 Pfam PF05593 RHS Repeat 721 759 3.6E-6 T 10-03-2017 IPR031325 RHS repeat RG49_RS17740 063a8b0e750f5bdb53a4f7923816a7ce 462 PIRSF PIRSF006060 11 460 2.5E-89 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS17740 063a8b0e750f5bdb53a4f7923816a7ce 462 Pfam PF13520 Amino acid permease 27 427 1.5E-59 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS23280 a1b3f0db2d213a76874f2397cd2e2bf2 416 Gene3D G3DSA:3.30.1540.10 246 326 2.4E-29 T 10-03-2017 RG49_RS23280 a1b3f0db2d213a76874f2397cd2e2bf2 416 Gene3D G3DSA:3.40.50.10540 2 216 1.7E-101 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS23280 a1b3f0db2d213a76874f2397cd2e2bf2 416 Gene3D G3DSA:3.40.50.10540 327 416 1.7E-101 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS23280 a1b3f0db2d213a76874f2397cd2e2bf2 416 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 1 416 65.257 T 10-03-2017 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695 RG49_RS23280 a1b3f0db2d213a76874f2397cd2e2bf2 416 SUPERFAMILY SSF89796 1 416 2.09E-125 T 10-03-2017 IPR023606 CoA-transferase family III domain RG49_RS23280 a1b3f0db2d213a76874f2397cd2e2bf2 416 Pfam PF02515 CoA-transferase family III 5 393 4.1E-94 T 10-03-2017 IPR003673 CoA-transferase family III GO:0003824 RG49_RS23280 a1b3f0db2d213a76874f2397cd2e2bf2 416 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 3 416 4.9E-237 T 10-03-2017 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695 RG49_RS18545 71a933af378f94e33fadd2a9289bd6e0 224 Gene3D G3DSA:2.60.40.1070 140 210 6.9E-6 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS18545 71a933af378f94e33fadd2a9289bd6e0 224 SUPERFAMILY SSF49584 140 218 6.15E-9 T 10-03-2017 IPR016148 Pili assembly chaperone, C-terminal RG49_RS18545 71a933af378f94e33fadd2a9289bd6e0 224 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 22 135 6.6E-23 T 10-03-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 RG49_RS18545 71a933af378f94e33fadd2a9289bd6e0 224 SUPERFAMILY SSF49354 17 135 3.4E-24 T 10-03-2017 IPR008962 PapD-like RG49_RS18545 71a933af378f94e33fadd2a9289bd6e0 224 Gene3D G3DSA:2.60.40.360 22 135 1.0E-18 T 10-03-2017 IPR008962 PapD-like RG49_RS06685 a8e81654c163ae51ea21155d832b4daa 592 Gene3D G3DSA:1.10.10.10 13 44 8.4E-4 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06685 a8e81654c163ae51ea21155d832b4daa 592 Pfam PF06056 Putative ATPase subunit of terminase (gpP-like) 11 68 8.9E-26 T 10-03-2017 IPR010332 ATPase terminase subunit, putative GO:0005524|GO:0019069 RG49_RS06685 a8e81654c163ae51ea21155d832b4daa 592 Pfam PF03237 Terminase-like family 162 571 1.2E-118 T 10-03-2017 IPR004921 Terminase, large subunit RG49_RS13195 3169d336a7eb386df7910f151357feb9 342 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 15 335 6.2E-161 T 10-03-2017 IPR022462 Lysine-2,3-aminomutase-like RG49_RS13195 3169d336a7eb386df7910f151357feb9 342 Gene3D G3DSA:3.20.20.70 104 315 2.7E-17 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS13195 3169d336a7eb386df7910f151357feb9 342 PIRSF PIRSF004911 1 342 3.6E-124 T 10-03-2017 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase RG49_RS13195 3169d336a7eb386df7910f151357feb9 342 TIGRFAM TIGR00238 TIGR00238: KamA family protein 3 328 2.9E-157 T 10-03-2017 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase RG49_RS13195 3169d336a7eb386df7910f151357feb9 342 SUPERFAMILY SSF102114 102 324 1.27E-25 T 10-03-2017 RG49_RS13195 3169d336a7eb386df7910f151357feb9 342 Pfam PF13353 4Fe-4S single cluster domain 112 176 1.7E-5 T 10-03-2017 RG49_RS13195 3169d336a7eb386df7910f151357feb9 342 Pfam PF04055 Radical SAM superfamily 118 263 6.9E-8 T 10-03-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 RG49_RS20140 f4294322f8fe84f7083d8f0e95c07b82 138 SMART SM00732 3 103 2.8E-43 T 10-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 RG49_RS20140 f4294322f8fe84f7083d8f0e95c07b82 138 Pfam PF03652 Holliday junction resolvase 4 135 9.2E-44 T 10-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 RG49_RS20140 f4294322f8fe84f7083d8f0e95c07b82 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 6 135 1.4E-62 T 10-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 RG49_RS20140 f4294322f8fe84f7083d8f0e95c07b82 138 Gene3D G3DSA:3.30.420.140 3 136 2.6E-48 T 10-03-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 RG49_RS20140 f4294322f8fe84f7083d8f0e95c07b82 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 3 138 26.471 T 10-03-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 RG49_RS20140 f4294322f8fe84f7083d8f0e95c07b82 138 SUPERFAMILY SSF53098 3 136 1.97E-43 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS13105 cc0fe12bf30642df7d3d635784fe57c9 181 SUPERFAMILY SSF53098 3 180 3.89E-49 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS13105 cc0fe12bf30642df7d3d635784fe57c9 181 Pfam PF00929 Exonuclease 9 170 2.2E-37 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS13105 cc0fe12bf30642df7d3d635784fe57c9 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 45.336 T 10-03-2017 IPR022894 Oligoribonuclease GO:0016788 RG49_RS13105 cc0fe12bf30642df7d3d635784fe57c9 181 Gene3D G3DSA:3.30.420.10 4 180 4.3E-72 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS13105 cc0fe12bf30642df7d3d635784fe57c9 181 SMART SM00479 7 180 1.2E-21 T 10-03-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III RG49_RS16500 bdf43d94844e8e1113c69c49f67c0e25 202 Gene3D G3DSA:3.40.30.10 1 89 1.7E-20 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS16500 bdf43d94844e8e1113c69c49f67c0e25 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 97 192 5.2E-11 T 10-03-2017 IPR004046 Glutathione S-transferase, C-terminal RG49_RS16500 bdf43d94844e8e1113c69c49f67c0e25 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 71 5.1E-13 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS16500 bdf43d94844e8e1113c69c49f67c0e25 202 Gene3D G3DSA:1.20.1050.10 90 197 1.9E-12 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS16500 bdf43d94844e8e1113c69c49f67c0e25 202 SUPERFAMILY SSF52833 1 100 1.28E-18 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS16500 bdf43d94844e8e1113c69c49f67c0e25 202 SUPERFAMILY SSF47616 73 199 3.13E-15 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS15855 c49f1625fc6661994a3d4ef3d74588c9 165 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 165 7.0E-99 T 10-03-2017 RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 Pfam PF07719 Tetratricopeptide repeat 96 129 5.2E-5 T 10-03-2017 IPR013105 Tetratricopeptide repeat 2 RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 PIRSF PIRSF004654 1 292 1.3E-122 T 10-03-2017 IPR023605 Lipoprotein NlpI RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 Gene3D G3DSA:1.25.40.10 49 267 3.3E-32 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 SUPERFAMILY SSF48452 27 283 1.57E-78 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 SMART SM00028 96 129 2.0E-4 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 SMART SM00028 62 95 0.0033 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 SMART SM00028 234 267 17.0 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS18830 2ce92cf2f06fc5a6d101faab7303c360 294 Pfam PF13181 Tetratricopeptide repeat 62 94 0.022 T 10-03-2017 IPR019734 Tetratricopeptide repeat GO:0005515 RG49_RS00420 a364105b35b80beaabd67a384340fbc1 329 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 26 319 2.4E-96 T 10-03-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain RG49_RS00420 a364105b35b80beaabd67a384340fbc1 329 SUPERFAMILY SSF53822 26 325 5.3E-71 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS00420 a364105b35b80beaabd67a384340fbc1 329 PIRSF PIRSF002816 1 326 3.2E-151 T 10-03-2017 IPR026266 L-arabinose-binding periplasmic protein GO:0042882 RG49_RS00420 a364105b35b80beaabd67a384340fbc1 329 Gene3D G3DSA:3.40.50.2300 148 296 7.8E-56 T 10-03-2017 RG49_RS00420 a364105b35b80beaabd67a384340fbc1 329 Gene3D G3DSA:3.40.50.2300 25 147 1.4E-44 T 10-03-2017 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 186 3.6E-14 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 SUPERFAMILY SSF47384 121 186 3.53E-12 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 SMART SM00388 129 194 2.5E-13 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 234 347 4.9E-17 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 SMART SM00387 233 349 1.2E-33 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 SUPERFAMILY SSF55874 198 346 6.42E-38 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 SUPERFAMILY SSF55785 11 104 9.18E-7 T 10-03-2017 IPR000014 PAS domain RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 Gene3D G3DSA:3.30.450.20 11 102 8.4E-21 T 10-03-2017 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 Pfam PF00989 PAS fold 11 99 2.8E-7 T 10-03-2017 IPR013767 PAS fold GO:0006355 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 Gene3D G3DSA:3.30.565.10 198 348 2.3E-38 T 10-03-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 Gene3D G3DSA:1.10.287.130 129 186 1.4E-10 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 295 1.2E-11 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 328 1.2E-11 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 346 1.2E-11 T 10-03-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 RG49_RS14835 57bebe9c13da525f9cde187fb901cd5e 349 SMART SM00091 7 75 4.0E-8 T 10-03-2017 IPR000014 PAS domain RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 SUPERFAMILY SSF54862 3 199 2.83E-71 T 10-03-2017 RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 Gene3D G3DSA:3.30.70.20 4 74 3.3E-18 T 10-03-2017 RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 Pfam PF12800 4Fe-4S binding domain 12 25 0.0026 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 Gene3D G3DSA:3.30.70.20 119 172 4.9E-19 T 10-03-2017 RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 4 163 6.5E-81 T 10-03-2017 IPR014297 Dimethylsulphoxide reductase, chain B RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 Gene3D G3DSA:3.30.70.20 75 118 1.2E-26 T 10-03-2017 RG49_RS06260 f64233bd1c609e5d66549657a48d9fe4 205 Pfam PF13247 4Fe-4S dicluster domain 59 153 9.1E-30 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS09670 4deb0a840e6405fdfad87f0936a60c19 78 SUPERFAMILY SSF159871 4 78 1.7E-11 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS09670 4deb0a840e6405fdfad87f0936a60c19 78 Gene3D G3DSA:3.30.1660.10 30 78 3.5E-9 T 10-03-2017 IPR025543 Dodecin-like RG49_RS09670 4deb0a840e6405fdfad87f0936a60c19 78 Pfam PF07338 Protein of unknown function (DUF1471) 30 78 2.5E-10 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS21580 c11d1ffc7edcb1f8cbb5fca7d846ee02 361 SUPERFAMILY SSF53955 46 356 3.66E-103 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS21580 c11d1ffc7edcb1f8cbb5fca7d846ee02 361 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 61 355 7.4E-131 T 10-03-2017 IPR011757 Lytic transglycosylase MltB RG49_RS21580 c11d1ffc7edcb1f8cbb5fca7d846ee02 361 Gene3D G3DSA:1.10.530.10 247 356 8.8E-59 T 10-03-2017 RG49_RS21580 c11d1ffc7edcb1f8cbb5fca7d846ee02 361 Gene3D G3DSA:1.10.530.10 113 166 8.8E-59 T 10-03-2017 RG49_RS21580 c11d1ffc7edcb1f8cbb5fca7d846ee02 361 Pfam PF13406 Transglycosylase SLT domain 57 353 2.6E-92 T 10-03-2017 IPR031304 Transglycosylase SLT domain 2 RG49_RS21415 687d7a57c0c238a46191b6eef0d1f544 117 ProDom PD075772 YGBA ECS3588 CYTOPLASMIC UVRA STM2860 AMIDOPHOSPHORIBOSYLTRANSFERASE VVA0912 SO0324 VPA0976 CPE0229 1 97 3.0E-52 T 10-03-2017 IPR020483 Uncharacterised protein family YgbA RG49_RS21415 687d7a57c0c238a46191b6eef0d1f544 117 Pfam PF11756 Nitrous oxide-stimulated promoter 4 106 4.9E-39 T 10-03-2017 IPR020483 Uncharacterised protein family YgbA RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 Pfam PF00529 HlyD membrane-fusion protein of T1SS 35 345 2.4E-18 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 289 1.6E-13 T 10-03-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 Gene3D G3DSA:2.40.50.100 215 248 2.6E-17 T 10-03-2017 RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 Gene3D G3DSA:2.40.50.100 60 94 2.6E-17 T 10-03-2017 RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 SUPERFAMILY SSF111369 57 107 9.68E-8 T 10-03-2017 RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 SUPERFAMILY SSF111369 136 178 9.68E-8 T 10-03-2017 RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 SUPERFAMILY SSF111369 195 268 9.02E-8 T 10-03-2017 RG49_RS21665 5976bc202774a6addd5b30b7feebb517 390 TIGRFAM TIGR00998 8a0101: efflux pump membrane protein 20 345 8.4E-150 T 10-03-2017 IPR005694 Efflux pump membrane protein Emr GO:0006855|GO:0015238 RG49_RS03030 81ceddaac98c865928b8e863f3bba063 231 Pfam PF02613 Nitrate reductase delta subunit 44 151 3.0E-11 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS03030 81ceddaac98c865928b8e863f3bba063 231 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 9 154 2.0E-34 T 10-03-2017 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 RG49_RS03030 81ceddaac98c865928b8e863f3bba063 231 SUPERFAMILY SSF89155 2 156 9.68E-27 T 10-03-2017 IPR020945 DMSO/Nitrate reductase chaperone RG49_RS18205 1e8553aa426f3356c6b6a2d9edccc0de 256 SUPERFAMILY SSF51161 77 248 3.88E-45 T 10-03-2017 IPR011004 Trimeric LpxA-like RG49_RS18205 1e8553aa426f3356c6b6a2d9edccc0de 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 85 119 6.2E-5 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS18205 1e8553aa426f3356c6b6a2d9edccc0de 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 169 202 2.4E-7 T 10-03-2017 IPR001451 Hexapeptide repeat RG49_RS18205 1e8553aa426f3356c6b6a2d9edccc0de 256 Gene3D G3DSA:2.160.10.10 74 248 8.4E-45 T 10-03-2017 RG49_RS03160 ea362bc405643937c211161733323f08 149 Pfam PF04657 Putative inner membrane exporter, YdcZ 6 143 4.5E-21 T 10-03-2017 IPR006750 Putative inner membrane exporter, YdcZ RG49_RS10485 dc744fab454245b67afe74913115ff1f 152 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 1 152 40.485 T 10-03-2017 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 RG49_RS10485 dc744fab454245b67afe74913115ff1f 152 Gene3D G3DSA:3.40.50.2020 1 145 8.2E-45 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS10485 dc744fab454245b67afe74913115ff1f 152 SUPERFAMILY SSF53271 4 144 4.2E-32 T 10-03-2017 IPR029057 Phosphoribosyltransferase-like RG49_RS10485 dc744fab454245b67afe74913115ff1f 152 Pfam PF00156 Phosphoribosyl transferase domain 11 144 1.5E-15 T 10-03-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 RG49_RS19475 9ee5e8cd4a58fd0545db42b085d37a2e 433 SMART SM01118 2 202 9.3E-42 T 10-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 RG49_RS19475 9ee5e8cd4a58fd0545db42b085d37a2e 433 Gene3D G3DSA:2.40.320.10 1 212 5.8E-50 T 10-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 RG49_RS19475 9ee5e8cd4a58fd0545db42b085d37a2e 433 SUPERFAMILY SSF55154 1 217 1.32E-54 T 10-03-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 RG49_RS19475 9ee5e8cd4a58fd0545db42b085d37a2e 433 Pfam PF01928 CYTH domain 3 196 5.5E-39 T 10-03-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 RG49_RS19475 9ee5e8cd4a58fd0545db42b085d37a2e 433 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 4 88 0.005 T 10-03-2017 RG49_RS06315 2457f4abafd37feb90a801064461ee69 234 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 35 203 1.6E-70 T 10-03-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 RG49_RS06315 2457f4abafd37feb90a801064461ee69 234 SUPERFAMILY SSF55729 2 228 1.17E-93 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS06315 2457f4abafd37feb90a801064461ee69 234 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 32 231 3.7E-95 T 10-03-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 RG49_RS06315 2457f4abafd37feb90a801064461ee69 234 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 234 97.301 T 10-03-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 RG49_RS18650 f4baa5ce636807ed5876dbd3f737e4c6 188 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 26 178 9.3E-78 T 10-03-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS18650 f4baa5ce636807ed5876dbd3f737e4c6 188 Gene3D G3DSA:3.40.50.1000 16 181 1.6E-49 T 10-03-2017 IPR023214 HAD-like domain RG49_RS18650 f4baa5ce636807ed5876dbd3f737e4c6 188 Pfam PF08282 haloacid dehalogenase-like hydrolase 93 158 4.0E-11 T 10-03-2017 IPR023214 HAD-like domain RG49_RS18650 f4baa5ce636807ed5876dbd3f737e4c6 188 SUPERFAMILY SSF56784 22 181 1.97E-41 T 10-03-2017 IPR023214 HAD-like domain RG49_RS18650 f4baa5ce636807ed5876dbd3f737e4c6 188 PIRSF PIRSF006118 13 188 1.0E-74 T 10-03-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 RG49_RS13460 6c9df68a5c22ee86aa19912b976ac7b6 259 SUPERFAMILY SSF161098 62 253 4.32E-36 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13460 6c9df68a5c22ee86aa19912b976ac7b6 259 Gene3D G3DSA:1.10.3720.10 60 258 5.0E-33 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13460 6c9df68a5c22ee86aa19912b976ac7b6 259 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 16 258 1.1E-93 T 10-03-2017 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 RG49_RS13460 6c9df68a5c22ee86aa19912b976ac7b6 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 258 1.2E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04885 baa88cf91a836015b220168f5d77b9c1 88 ProDom PD865043 PLASMID SPA-ORF10 3'REGION CYTOPLASMIC ORF-10 SPAS STY1854 30 88 6.0E-5 T 10-03-2017 IPR024753 Regulatory protein AriR GO:0042710|GO:0071229 RG49_RS04885 baa88cf91a836015b220168f5d77b9c1 88 Pfam PF10798 Biofilm development protein YmgB/AriR 29 87 8.2E-24 T 10-03-2017 IPR024753 Regulatory protein AriR GO:0042710|GO:0071229 RG49_RS15930 3c9bacd07595e0776ad06cca96c29783 444 PIRSF PIRSF005353 6 444 1.2E-169 T 10-03-2017 IPR026033 Purine permease PbuG-like RG49_RS15930 3c9bacd07595e0776ad06cca96c29783 444 Pfam PF00860 Permease family 32 405 2.5E-44 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS21330 bee8a9d02e03015c15fe1ba853b07055 103 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 35.875 T 10-03-2017 IPR023081 Cell division protein FtsB RG49_RS21330 bee8a9d02e03015c15fe1ba853b07055 103 Pfam PF04977 Septum formation initiator 11 89 4.1E-30 T 10-03-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 RG49_RS21065 a2d33d253e6e9539162415e9d2feb4b5 429 TIGRFAM TIGR00814 stp: serine transporter 18 418 1.1E-186 T 10-03-2017 IPR004694 Hydroxy amino acid transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS22120 0cc48a60b246695cb57422c52f7e5c5c 232 SMART SM01144 27 218 3.3E-72 T 10-03-2017 IPR005636 DTW RG49_RS22120 0cc48a60b246695cb57422c52f7e5c5c 232 Pfam PF03942 DTW domain 30 210 2.8E-43 T 10-03-2017 IPR005636 DTW RG49_RS06825 9dbf9ce8120b14c0c53088d087bd7f43 127 ProDom PD079626 YLIH RECEPTOR STY0893 CYTOPLASMIC 1 127 6.0E-61 T 10-03-2017 IPR020359 Biofilm regulator BssR RG49_RS06825 9dbf9ce8120b14c0c53088d087bd7f43 127 Pfam PF10799 Biofilm formation protein (YliH/bssR) 1 126 1.0E-75 T 10-03-2017 IPR020359 Biofilm regulator BssR RG49_RS20420 0d986c2a68300d28eda21d61a24fe99c 135 ProDom PD083358 MEMBRANE YGFX INNER SIMILAR ECS3768 Y3281 ESCHERICHIA TRANSMEMBRANE YPO0896A STY3202 19 131 2.0E-58 T 10-03-2017 IPR009883 Toxin CptA RG49_RS20420 0d986c2a68300d28eda21d61a24fe99c 135 Pfam PF07254 Membrane-bound toxin component of toxin-antitoxin system 2 129 5.2E-56 T 10-03-2017 IPR009883 Toxin CptA RG49_RS20420 0d986c2a68300d28eda21d61a24fe99c 135 PIRSF PIRSF020653 1 135 3.5E-79 T 10-03-2017 IPR009883 Toxin CptA RG49_RS01985 c19f5af07478ebf18d5e471aa75b2b21 421 Gene3D G3DSA:2.40.160.10 35 387 9.7E-17 T 10-03-2017 IPR023614 Porin domain RG49_RS01985 c19f5af07478ebf18d5e471aa75b2b21 421 Pfam PF03573 outer membrane porin, OprD family 38 391 7.6E-6 T 10-03-2017 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 RG49_RS03235 2cd987586fc588c4ed931bb6c8fe179e 178 Gene3D G3DSA:1.10.260.40 2 79 1.6E-25 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS03235 2cd987586fc588c4ed931bb6c8fe179e 178 Pfam PF01381 Helix-turn-helix 12 64 1.0E-16 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS03235 2cd987586fc588c4ed931bb6c8fe179e 178 Pfam PF07883 Cupin domain 105 171 1.8E-9 T 10-03-2017 IPR013096 Cupin 2, conserved barrel RG49_RS03235 2cd987586fc588c4ed931bb6c8fe179e 178 SUPERFAMILY SSF51182 51 176 2.35E-22 T 10-03-2017 IPR011051 RmlC-like cupin domain RG49_RS03235 2cd987586fc588c4ed931bb6c8fe179e 178 SUPERFAMILY SSF47413 4 71 1.39E-18 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS03235 2cd987586fc588c4ed931bb6c8fe179e 178 SMART SM00530 11 66 1.2E-15 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS03235 2cd987586fc588c4ed931bb6c8fe179e 178 Gene3D G3DSA:2.60.120.10 85 177 3.3E-34 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS24125 c2016f296eb42227d9dfe25bc81b90e6 149 SUPERFAMILY SSF48695 48 145 2.26E-40 T 10-03-2017 IPR011031 Multihaem cytochrome RG49_RS24125 c2016f296eb42227d9dfe25bc81b90e6 149 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 40 142 6.3E-43 T 10-03-2017 IPR005591 Nitrate reductase cytochrome c-type subunit NapB RG49_RS24125 c2016f296eb42227d9dfe25bc81b90e6 149 PIRSF PIRSF006105 3 149 3.2E-54 T 10-03-2017 IPR005591 Nitrate reductase cytochrome c-type subunit NapB RG49_RS24125 c2016f296eb42227d9dfe25bc81b90e6 149 Gene3D G3DSA:4.10.1020.10 62 129 5.9E-33 T 10-03-2017 IPR027406 Periplasmic nitrate reductase NapB subunit, heme binding domain RG49_RS10820 8cc05077228007da2d3a7bf7635361b4 217 SUPERFAMILY SSF161098 9 201 2.35E-47 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS10820 8cc05077228007da2d3a7bf7635361b4 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 216 1.8E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS10820 8cc05077228007da2d3a7bf7635361b4 217 Gene3D G3DSA:1.10.3720.10 9 214 3.8E-42 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS08135 95856758bc910f75b955633a0b386897 65 Pfam PF04328 Protein of unknown function (DUF466) 5 65 8.7E-31 T 10-03-2017 IPR007423 Protein of unknown function DUF466 RG49_RS18985 2c25f8c3f69a93988153ec5f5be1b7ce 144 SUPERFAMILY SSF53062 1 126 1.44E-34 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS18985 2c25f8c3f69a93988153ec5f5be1b7ce 144 Gene3D G3DSA:3.40.50.510 1 135 4.6E-39 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS18985 2c25f8c3f69a93988153ec5f5be1b7ce 144 Pfam PF03610 PTS system fructose IIA component 4 113 2.0E-27 T 10-03-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 RG49_RS06155 af7bab116b1ac87fc950d1c25e45ca35 410 Pfam PF06224 Winged helix DNA-binding domain 38 381 8.0E-84 T 10-03-2017 IPR009351 Protein of unknown function DUF1006 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Gene3D G3DSA:3.30.1360.30 276 414 1.5E-47 T 10-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 586 2.6E-281 T 10-03-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 558 1.0E-106 T 10-03-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Pfam PF02938 GAD domain 307 406 6.3E-32 T 10-03-2017 IPR029351 GAD domain Reactome: R-HSA-379726 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Gene3D G3DSA:2.40.50.140 1 106 6.6E-40 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 1 563 37.142 T 10-03-2017 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 SUPERFAMILY SSF55261 288 419 1.0E-46 T 10-03-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 6.3E-17 T 10-03-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 1.2E-26 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 1.2E-26 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 1.2E-26 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 1.2E-26 T 10-03-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Gene3D G3DSA:3.30.930.10 415 585 3.5E-112 T 10-03-2017 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 Gene3D G3DSA:3.30.930.10 131 275 3.5E-112 T 10-03-2017 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 SUPERFAMILY SSF50249 1 105 1.18E-34 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 SUPERFAMILY SSF55681 108 287 1.7E-106 T 10-03-2017 RG49_RS00585 b0e3a6ee8141cd32ca4ae3b08c47a7ac 590 SUPERFAMILY SSF55681 420 584 1.7E-106 T 10-03-2017 RG49_RS19085 573051b1bb92bf0f311ab95f0d433b84 270 Gene3D G3DSA:3.30.420.10 97 256 1.2E-39 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS19085 573051b1bb92bf0f311ab95f0d433b84 270 Pfam PF00665 Integrase core domain 104 217 4.1E-35 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS19085 573051b1bb92bf0f311ab95f0d433b84 270 Pfam PF13276 HTH-like domain 23 76 2.0E-11 T 10-03-2017 IPR025948 HTH-like domain RG49_RS19085 573051b1bb92bf0f311ab95f0d433b84 270 SUPERFAMILY SSF53098 96 260 8.6E-44 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS06730 a0f9ac6ab4c18f9fc3d45db592bf8658 75 SUPERFAMILY SSF57716 34 71 4.56E-9 T 10-03-2017 RG49_RS06730 a0f9ac6ab4c18f9fc3d45db592bf8658 75 TIGRFAM TIGR02419 C4_traR_proteo: phage/conjugal plasmid C-4 type zinc finger protein, TraR family 3 64 1.0E-18 T 10-03-2017 IPR012783 Zinc finger, C4 DksA/TraR-type RG49_RS06730 a0f9ac6ab4c18f9fc3d45db592bf8658 75 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 32 64 2.4E-11 T 10-03-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 RG49_RS06970 23b8aa955e966f3380b21e304332387f 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 1.2E-25 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06970 23b8aa955e966f3380b21e304332387f 219 Gene3D G3DSA:1.10.3720.10 13 217 4.4E-50 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06970 23b8aa955e966f3380b21e304332387f 219 SUPERFAMILY SSF161098 13 202 4.71E-46 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS06970 23b8aa955e966f3380b21e304332387f 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 111 3.7E-32 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS08280 ed6b170241dcc61c2768c47b9669987e 217 Pfam PF00881 Nitroreductase family 8 193 1.0E-34 T 10-03-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 RG49_RS08280 ed6b170241dcc61c2768c47b9669987e 217 Gene3D G3DSA:3.40.109.10 1 214 3.3E-60 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS08280 ed6b170241dcc61c2768c47b9669987e 217 SUPERFAMILY SSF55469 1 216 3.93E-64 T 10-03-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 RG49_RS03585 1bf2babd55b51f083b1bd4860c1e9895 364 Pfam PF03592 Terminase small subunit 121 316 1.5E-8 T 10-03-2017 IPR005335 Terminase small subunit GO:0006323 RG49_RS12205 0abcc9f93f76ae86d1e31cc55d34fcc1 126 SUPERFAMILY SSF55331 2 126 3.11E-46 T 10-03-2017 IPR014347 Tautomerase/MIF superfamily RG49_RS12205 0abcc9f93f76ae86d1e31cc55d34fcc1 126 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 124 3.0E-24 T 10-03-2017 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 RG49_RS12205 0abcc9f93f76ae86d1e31cc55d34fcc1 126 Gene3D G3DSA:3.30.429.10 1 126 2.5E-50 T 10-03-2017 RG49_RS02165 54660bbf25f0bf133109f2ee28f1c11c 108 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 2 106 22.345 T 10-03-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 RG49_RS02165 54660bbf25f0bf133109f2ee28f1c11c 108 SUPERFAMILY SSF103481 8 105 1.06E-5 T 10-03-2017 RG49_RS02165 54660bbf25f0bf133109f2ee28f1c11c 108 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 1 107 5.5E-49 T 10-03-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 RG49_RS10645 88483bbf80057f63c8f8c13c9e4bcb74 616 PIRSF PIRSF028304 1 616 4.4E-217 T 10-03-2017 IPR010272 Type VI secretion system, TssF-like RG49_RS10645 88483bbf80057f63c8f8c13c9e4bcb74 616 Pfam PF05947 Type VI secretion system, ImpG, VasA, VC_A0110 6 615 3.1E-169 T 10-03-2017 IPR010272 Type VI secretion system, TssF-like RG49_RS10645 88483bbf80057f63c8f8c13c9e4bcb74 616 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 6 616 4.3E-168 T 10-03-2017 IPR010272 Type VI secretion system, TssF-like RG49_RS19040 638f804e06ce31fe602a43c2d4c5e6b4 256 TIGRFAM TIGR03239 GarL: 2-dehydro-3-deoxyglucarate aldolase 8 256 3.7E-148 T 10-03-2017 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20 RG49_RS19040 638f804e06ce31fe602a43c2d4c5e6b4 256 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 245 1.6E-62 T 10-03-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 RG49_RS19040 638f804e06ce31fe602a43c2d4c5e6b4 256 Hamap MF_01291 5-keto-4-deoxy-D-glucarate aldolase [garL]. 1 256 68.893 T 10-03-2017 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20 RG49_RS19040 638f804e06ce31fe602a43c2d4c5e6b4 256 SUPERFAMILY SSF51621 4 255 3.14E-82 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS19040 638f804e06ce31fe602a43c2d4c5e6b4 256 Gene3D G3DSA:3.20.20.60 6 255 1.1E-78 T 10-03-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 RG49_RS24805 a396adc21a8845949c393d43cd25fd60 415 SUPERFAMILY SSF111369 79 313 1.7E-54 T 10-03-2017 RG49_RS24805 a396adc21a8845949c393d43cd25fd60 415 Gene3D G3DSA:2.40.50.100 195 229 9.2E-24 T 10-03-2017 RG49_RS24805 a396adc21a8845949c393d43cd25fd60 415 Gene3D G3DSA:2.40.50.100 86 120 9.2E-24 T 10-03-2017 RG49_RS24805 a396adc21a8845949c393d43cd25fd60 415 Pfam PF13533 Biotin-lipoyl like 87 135 1.4E-15 T 10-03-2017 RG49_RS24805 a396adc21a8845949c393d43cd25fd60 415 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 62 390 1.4E-77 T 10-03-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 RG49_RS24805 a396adc21a8845949c393d43cd25fd60 415 Pfam PF13437 HlyD family secretion protein 198 301 6.7E-9 T 10-03-2017 RG49_RS24805 a396adc21a8845949c393d43cd25fd60 415 Hamap MF_01422 Multidrug resistance protein MdtA [mdtA]. 1 413 55.003 T 10-03-2017 IPR022824 Multidrug resistance protein MdtA RG49_RS12065 8c23dcd724defdfc273aaee51bbabc62 148 Pfam PF00583 Acetyltransferase (GNAT) family 47 120 7.0E-19 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS12065 8c23dcd724defdfc273aaee51bbabc62 148 Gene3D G3DSA:3.40.630.30 3 147 1.6E-36 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS12065 8c23dcd724defdfc273aaee51bbabc62 148 SUPERFAMILY SSF55729 3 146 3.49E-34 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS12065 8c23dcd724defdfc273aaee51bbabc62 148 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 11 142 4.3E-48 T 10-03-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 RG49_RS12755 60fd77b76fba061cc678c830f21a5169 318 SUPERFAMILY SSF53822 23 310 4.21E-72 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS12755 60fd77b76fba061cc678c830f21a5169 318 Pfam PF13407 Periplasmic binding protein domain 26 274 8.5E-45 T 10-03-2017 IPR025997 Periplasmic binding protein RG49_RS12755 60fd77b76fba061cc678c830f21a5169 318 Gene3D G3DSA:3.40.50.2300 140 308 1.9E-45 T 10-03-2017 RG49_RS12755 60fd77b76fba061cc678c830f21a5169 318 Gene3D G3DSA:3.40.50.2300 25 139 2.0E-28 T 10-03-2017 RG49_RS18990 39cf10cc54ad0e25226e848764bc1cf1 292 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 36 291 1.6E-92 T 10-03-2017 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 SMART SM00382 29 219 7.5E-12 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 Pfam PF00005 ABC transporter 21 162 1.8E-28 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 Gene3D G3DSA:2.40.50.140 286 344 1.2E-13 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 SUPERFAMILY SSF52540 4 243 6.28E-84 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 Gene3D G3DSA:3.40.50.300 3 234 8.0E-75 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 SUPERFAMILY SSF50331 237 359 5.83E-28 T 10-03-2017 IPR008995 Molybdate/tungstate binding, C-terminal RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 Gene3D G3DSA:2.40.50.100 240 285 4.2E-20 T 10-03-2017 RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 Gene3D G3DSA:2.40.50.100 345 359 4.2E-20 T 10-03-2017 RG49_RS03950 99c12948a8d9093ce02bbf572c2c4219 360 Pfam PF08402 TOBE domain 281 351 1.1E-8 T 10-03-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 Pfam PF01494 FAD binding domain 4 251 5.3E-60 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 Gene3D G3DSA:3.50.50.60 174 254 4.7E-36 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 Gene3D G3DSA:3.50.50.60 15 91 4.7E-36 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 65 80 2.4E-25 T 10-03-2017 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 219 237 2.4E-25 T 10-03-2017 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 186 201 2.4E-25 T 10-03-2017 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 201 217 2.4E-25 T 10-03-2017 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 237 253 2.4E-25 T 10-03-2017 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 SUPERFAMILY SSF51905 10 86 3.22E-42 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS09955 e85667f884a1dce87d4bb8d4177e5d4a 453 SUPERFAMILY SSF51905 173 287 3.22E-42 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS01700 3d5216708170fb6b28e34ff38f616c53 101 SUPERFAMILY SSF54909 4 96 7.75E-34 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS01700 3d5216708170fb6b28e34ff38f616c53 101 Pfam PF08803 Putative mono-oxygenase ydhR 4 98 1.3E-41 T 10-03-2017 IPR014910 Putative monooxygenase YdhR RG49_RS08770 d05cc26d0c280b18e3a5ff1c55bc4a0b 53 Pfam PF10689 Protein of unknown function (DUF2496) 2 44 1.1E-23 T 10-03-2017 IPR019630 Protein of unknown function DUF2496, YbaM-related RG49_RS03345 559ccb209ced7c536f4e0f12ef5f3129 78 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 1 63 2.4E-12 T 10-03-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 RG49_RS03345 559ccb209ced7c536f4e0f12ef5f3129 78 Gene3D G3DSA:3.30.360.10 1 65 4.7E-13 T 10-03-2017 RG49_RS03345 559ccb209ced7c536f4e0f12ef5f3129 78 SUPERFAMILY SSF55347 1 64 6.54E-13 T 10-03-2017 RG49_RS08900 e016ac1429a3f688333e890176de2690 231 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 206 3.5E-89 T 10-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 RG49_RS08900 e016ac1429a3f688333e890176de2690 231 Pfam PF06508 Queuosine biosynthesis protein QueC 3 213 7.9E-85 T 10-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 RG49_RS08900 e016ac1429a3f688333e890176de2690 231 PIRSF PIRSF006293 1 226 1.1E-88 T 10-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 RG49_RS08900 e016ac1429a3f688333e890176de2690 231 Gene3D G3DSA:3.40.50.620 1 222 1.4E-86 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS08900 e016ac1429a3f688333e890176de2690 231 SUPERFAMILY SSF52402 1 221 8.38E-72 T 10-03-2017 RG49_RS08900 e016ac1429a3f688333e890176de2690 231 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 219 53.172 T 10-03-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 RG49_RS03905 31403e1c034249f9d552a8e7d60207ab 60 Gene3D G3DSA:3.40.50.720 1 45 3.6E-7 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03905 31403e1c034249f9d552a8e7d60207ab 60 SUPERFAMILY SSF51735 1 44 2.06E-6 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18420 bdbe440e2ad8483e6a2433e9023fd118 655 Pfam PF04632 Fusaric acid resistance protein family 11 652 6.9E-166 T 10-03-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 RG49_RS18420 bdbe440e2ad8483e6a2433e9023fd118 655 Hamap MF_01545 p-hydroxybenzoic acid efflux pump subunit AaeB [aaeB]. 3 653 54.872 T 10-03-2017 IPR023706 Para-hydroxybenzoic acid efflux pump, subunit AaeB GO:0005886|GO:0006810 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 4.4E-9 T 10-03-2017 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 4.4E-9 T 10-03-2017 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 4.4E-9 T 10-03-2017 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 305 329 4.4E-9 T 10-03-2017 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 403 422 4.4E-9 T 10-03-2017 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 Pfam PF07690 Major Facilitator Superfamily 22 412 6.2E-50 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 Gene3D G3DSA:1.20.1250.20 272 448 2.3E-21 T 10-03-2017 RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 SUPERFAMILY SSF103473 251 452 4.05E-63 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 SUPERFAMILY SSF103473 10 195 4.05E-63 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS00810 47aa65fd7bc05ca0bf19dee40648f1de 457 Gene3D G3DSA:1.20.1250.20 15 195 5.4E-26 T 10-03-2017 RG49_RS17320 ae4852e74e0ff9f9e525468243dc365b 295 Gene3D G3DSA:1.10.3720.10 62 291 6.6E-54 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17320 ae4852e74e0ff9f9e525468243dc365b 295 SUPERFAMILY SSF161098 56 282 2.49E-52 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17320 ae4852e74e0ff9f9e525468243dc365b 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 293 4.8E-20 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 37 43 - T 10-03-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 SUPERFAMILY SSF53335 15 257 4.04E-62 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 Pfam PF01555 DNA methylase 34 250 4.9E-53 T 10-03-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 237 257 2.5E-39 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 68 88 2.5E-39 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 195 212 2.5E-39 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 214 232 2.5E-39 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 33 47 2.5E-39 T 10-03-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 RG49_RS18295 2fed4e5d0232982820ace73ff80f6601 294 Gene3D G3DSA:3.40.50.150 14 284 9.8E-72 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS02870 1eb6f5d3c5a435f999a6c3dca49a68d4 511 PIRSF PIRSF006060 6 483 2.5E-67 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS02870 1eb6f5d3c5a435f999a6c3dca49a68d4 511 TIGRFAM TIGR00910 2A0307_GadC: glutamate:gamma-aminobutyrate antiporter 1 511 0.0 T 10-03-2017 IPR004759 Glutamate:g-aminobutyrate antiporter GO:0006865|GO:0016021 RG49_RS02870 1eb6f5d3c5a435f999a6c3dca49a68d4 511 Pfam PF13520 Amino acid permease 13 451 3.1E-56 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS15480 301f47abd1f028ba65c3bac5d439af81 498 Pfam PF12592 Protein of unknown function (DUF3763) 444 497 3.6E-22 T 10-03-2017 IPR022547 ATPase, RavA, C-terminal GO:0016820 RG49_RS15480 301f47abd1f028ba65c3bac5d439af81 498 Hamap MF_01625 ATPase RavA [ravA]. 1 498 59.136 T 10-03-2017 IPR023671 ATPase RavA GO:0005737|GO:0016887 RG49_RS15480 301f47abd1f028ba65c3bac5d439af81 498 Gene3D G3DSA:3.40.50.300 25 183 4.5E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS15480 301f47abd1f028ba65c3bac5d439af81 498 Pfam PF07728 AAA domain (dynein-related subfamily) 41 171 6.3E-25 T 10-03-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 RG49_RS15480 301f47abd1f028ba65c3bac5d439af81 498 SMART SM00382 38 187 1.6E-5 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS15480 301f47abd1f028ba65c3bac5d439af81 498 SUPERFAMILY SSF52540 12 264 4.63E-19 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS14500 0727d21bd1dcd776163eb3b8bb638838 336 Gene3D G3DSA:3.30.540.10 1 170 2.0E-70 T 10-03-2017 RG49_RS14500 0727d21bd1dcd776163eb3b8bb638838 336 Gene3D G3DSA:3.30.540.10 171 332 6.1E-49 T 10-03-2017 RG49_RS14500 0727d21bd1dcd776163eb3b8bb638838 336 PIRSF PIRSF004532 1 333 6.4E-143 T 10-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 RG49_RS14500 0727d21bd1dcd776163eb3b8bb638838 336 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 322 5.7E-133 T 10-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 RG49_RS14500 0727d21bd1dcd776163eb3b8bb638838 336 SUPERFAMILY SSF56655 2 325 6.71E-112 T 10-03-2017 RG49_RS14500 0727d21bd1dcd776163eb3b8bb638838 336 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 335 8.0E-189 T 10-03-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 RG49_RS23345 9ab96bc127def8e4c7d2adb170a065b9 251 PRINTS PR01805 VacJ lipoprotein signature 30 43 4.9E-35 T 10-03-2017 IPR007428 MlaA lipoprotein GO:0016020 RG49_RS23345 9ab96bc127def8e4c7d2adb170a065b9 251 PRINTS PR01805 VacJ lipoprotein signature 48 64 4.9E-35 T 10-03-2017 IPR007428 MlaA lipoprotein GO:0016020 RG49_RS23345 9ab96bc127def8e4c7d2adb170a065b9 251 PRINTS PR01805 VacJ lipoprotein signature 138 155 4.9E-35 T 10-03-2017 IPR007428 MlaA lipoprotein GO:0016020 RG49_RS23345 9ab96bc127def8e4c7d2adb170a065b9 251 PRINTS PR01805 VacJ lipoprotein signature 99 116 4.9E-35 T 10-03-2017 IPR007428 MlaA lipoprotein GO:0016020 RG49_RS23345 9ab96bc127def8e4c7d2adb170a065b9 251 Pfam PF04333 MlaA lipoprotein 29 222 1.4E-66 T 10-03-2017 IPR007428 MlaA lipoprotein GO:0016020 RG49_RS21245 4263b2e59b15bef4b65ed6b43507b24c 50 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 10 29 - T 10-03-2017 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 RG49_RS21245 4263b2e59b15bef4b65ed6b43507b24c 50 Pfam PF01848 Hok/gef family 5 46 5.2E-20 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS21245 4263b2e59b15bef4b65ed6b43507b24c 50 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 1 49 6.0E-20 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS21245 4263b2e59b15bef4b65ed6b43507b24c 50 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 47 7.7E-11 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS21245 4263b2e59b15bef4b65ed6b43507b24c 50 PRINTS PR00281 Hok/Gef cell toxic protein family signature 5 23 7.7E-11 T 10-03-2017 IPR000021 Hok/gef cell toxic protein GO:0016020 RG49_RS25035 db0d0c592029e4e78a30f87f0da222cb 314 SUPERFAMILY SSF53448 8 228 1.13E-39 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS25035 db0d0c592029e4e78a30f87f0da222cb 314 Gene3D G3DSA:3.90.550.10 8 227 1.3E-35 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS25035 db0d0c592029e4e78a30f87f0da222cb 314 Pfam PF00535 Glycosyl transferase family 2 11 113 5.2E-18 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS25240 5ebb0cbab0cc526d65d696cb9687e11b 147 Gene3D G3DSA:3.40.930.10 13 132 4.7E-27 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS25240 5ebb0cbab0cc526d65d696cb9687e11b 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 13 130 9.1E-20 T 10-03-2017 IPR002178 PTS EIIA type-2 domain RG49_RS25240 5ebb0cbab0cc526d65d696cb9687e11b 147 SUPERFAMILY SSF55804 12 133 3.27E-26 T 10-03-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 RG49_RS18480 0344807a9a3d95e3bb0f87f63128f377 165 Gene3D G3DSA:2.30.30.220 4 111 1.5E-52 T 10-03-2017 IPR007481 Stringent starvation protein B RG49_RS18480 0344807a9a3d95e3bb0f87f63128f377 165 SUPERFAMILY SSF101738 4 119 7.46E-49 T 10-03-2017 IPR007481 Stringent starvation protein B RG49_RS18480 0344807a9a3d95e3bb0f87f63128f377 165 PIRSF PIRSF005276 3 165 1.1E-61 T 10-03-2017 IPR007481 Stringent starvation protein B RG49_RS18480 0344807a9a3d95e3bb0f87f63128f377 165 Pfam PF04386 Stringent starvation protein B 9 165 1.2E-45 T 10-03-2017 IPR007481 Stringent starvation protein B RG49_RS21740 c003da0fb50adf0486e1f4625ded4e31 149 Hamap MF_00914 L-alanine exporter AlaE [alaE]. 1 144 35.008 T 10-03-2017 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 RG49_RS21740 c003da0fb50adf0486e1f4625ded4e31 149 Pfam PF06610 L-alanine exporter 4 141 1.4E-68 T 10-03-2017 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 RG49_RS21740 c003da0fb50adf0486e1f4625ded4e31 149 ProDom PD090021 MEMBRANE YGAW TRANSMEMBRANE INNER VV2263 Y3636 VC1828 VP1070 8 141 1.0E-73 T 10-03-2017 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 RG49_RS22835 58d8812bf4ba5e8a835e39f72b0e4ec2 191 Pfam PF00293 NUDIX domain 45 163 2.6E-9 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS22835 58d8812bf4ba5e8a835e39f72b0e4ec2 191 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 2 186 4.7E-82 T 10-03-2017 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 RG49_RS22835 58d8812bf4ba5e8a835e39f72b0e4ec2 191 SUPERFAMILY SSF55811 8 188 5.82E-50 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS22835 58d8812bf4ba5e8a835e39f72b0e4ec2 191 Gene3D G3DSA:3.90.79.10 4 186 1.4E-58 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS10870 08de24ea625185059fa88f56695d2bc8 86 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF) 9 83 4.0E-29 T 10-03-2017 IPR009778 Modulator of Rho-dependent transcription termination RG49_RS10870 08de24ea625185059fa88f56695d2bc8 86 SUPERFAMILY SSF101744 1 85 6.8E-30 T 10-03-2017 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 RG49_RS10475 6c8dd41a84c186a2e9de5a79e5c2d176 133 Pfam PF07417 Transcriptional regulator Crl 5 122 6.2E-54 T 10-03-2017 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 RG49_RS10475 6c8dd41a84c186a2e9de5a79e5c2d176 133 Hamap MF_01178 Sigma factor-binding protein Crl [crl]. 1 128 32.458 T 10-03-2017 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 RG49_RS21725 769ae15e7d32e4f9c4bfe2c535bf870f 81 SUPERFAMILY SSF52833 1 72 3.66E-21 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS21725 769ae15e7d32e4f9c4bfe2c535bf870f 81 Gene3D G3DSA:3.40.30.10 1 75 6.4E-29 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS21725 769ae15e7d32e4f9c4bfe2c535bf870f 81 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 8.0E-34 T 10-03-2017 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 RG49_RS21725 769ae15e7d32e4f9c4bfe2c535bf870f 81 Pfam PF00462 Glutaredoxin 3 57 2.7E-13 T 10-03-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 RG49_RS18530 9d227e91f40487aec287306f3218866a 238 Pfam PF06551 Protein of unknown function (DUF1120) 29 138 2.5E-44 T 10-03-2017 IPR010546 Protein of unknown function DUF1120 RG49_RS06565 255a734c5b750684b58894b173f77210 100 Pfam PF10109 Phage tail assembly chaperone proteins, E, or 41 or 14 9 88 3.1E-15 T 10-03-2017 IPR019289 Bacteriophage tail protein Gp41, putative RG49_RS15475 a2ea77af70193144cfef5c74f92f70d7 622 TIGRFAM TIGR00794 kup: potassium uptake protein 97 550 8.0E-202 T 10-03-2017 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 RG49_RS15475 a2ea77af70193144cfef5c74f92f70d7 622 Pfam PF02705 K+ potassium transporter 14 544 9.8E-206 T 10-03-2017 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 RG49_RS15475 a2ea77af70193144cfef5c74f92f70d7 622 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 5 622 33.363 T 10-03-2017 IPR023051 Potassium uptake protein, low affinity, Kup RG49_RS20415 9c8f7929d68cfe51e355a10748a5d223 88 Pfam PF03937 Flavinator of succinate dehydrogenase 6 75 1.2E-25 T 10-03-2017 IPR005631 Flavinator of succinate dehydrogenase RG49_RS20415 9c8f7929d68cfe51e355a10748a5d223 88 SUPERFAMILY SSF109910 1 78 4.18E-27 T 10-03-2017 IPR005631 Flavinator of succinate dehydrogenase RG49_RS20415 9c8f7929d68cfe51e355a10748a5d223 88 Gene3D G3DSA:1.10.150.250 2 85 3.9E-32 T 10-03-2017 IPR005631 Flavinator of succinate dehydrogenase RG49_RS16775 d1cdacd5d00da33b7dba0df200229b25 535 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 79 101 - T 10-03-2017 IPR023765 Solute-binding protein family 5, conserved site RG49_RS16775 d1cdacd5d00da33b7dba0df200229b25 535 Gene3D G3DSA:3.90.76.10 39 219 4.1E-50 T 10-03-2017 RG49_RS16775 d1cdacd5d00da33b7dba0df200229b25 535 PIRSF PIRSF002741 21 535 1.6E-121 T 10-03-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 RG49_RS16775 d1cdacd5d00da33b7dba0df200229b25 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 453 4.2E-108 T 10-03-2017 IPR000914 Solute-binding protein family 5 domain RG49_RS16775 d1cdacd5d00da33b7dba0df200229b25 535 SUPERFAMILY SSF53850 29 534 1.07E-162 T 10-03-2017 RG49_RS16775 d1cdacd5d00da33b7dba0df200229b25 535 Gene3D G3DSA:3.10.105.10 288 505 5.6E-69 T 10-03-2017 RG49_RS17705 bef5d48e4e4e5654ec3bba74bce24dce 434 Pfam PF10797 Protein of unknown function 6 431 3.7E-171 T 10-03-2017 IPR019733 Uncharacterised protein family YhfT RG49_RS13560 5a4af81f8333785c92397ad10b347023 231 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 29 43 - T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS13560 5a4af81f8333785c92397ad10b347023 231 Gene3D G3DSA:3.20.20.70 1 223 4.1E-77 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS13560 5a4af81f8333785c92397ad10b347023 231 Pfam PF00834 Ribulose-phosphate 3 epimerase family 2 196 6.9E-61 T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS13560 5a4af81f8333785c92397ad10b347023 231 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 10-03-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 RG49_RS13560 5a4af81f8333785c92397ad10b347023 231 SUPERFAMILY SSF51366 1 214 2.26E-58 T 10-03-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 RG49_RS20210 5c9a05397a9e983ceb13bcff0c3df5f1 252 Pfam PF01435 Peptidase family M48 71 245 3.5E-26 T 10-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 RG49_RS20210 5c9a05397a9e983ceb13bcff0c3df5f1 252 Gene3D G3DSA:3.30.2010.10 65 145 2.4E-23 T 10-03-2017 RG49_RS13960 2ad1e07b049baa236cacec426fe168ce 229 Pfam PF03575 Peptidase family S51 3 205 3.8E-62 T 10-03-2017 IPR005320 Peptidase S51 GO:0006508|GO:0008236 RG49_RS13960 2ad1e07b049baa236cacec426fe168ce 229 SUPERFAMILY SSF52317 1 220 9.16E-43 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS13960 2ad1e07b049baa236cacec426fe168ce 229 Gene3D G3DSA:3.40.50.880 1 227 4.5E-77 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS13960 2ad1e07b049baa236cacec426fe168ce 229 Hamap MF_00510 Peptidase E [pepE]. 1 215 48.775 T 10-03-2017 IPR023172 Peptidase S51, dipeptidase E GO:0016805 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 SUPERFAMILY SSF53850 91 322 1.47E-46 T 10-03-2017 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.6E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.6E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.6E-7 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 Gene3D G3DSA:3.40.190.10 185 261 6.9E-32 T 10-03-2017 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 Gene3D G3DSA:3.40.190.10 92 184 6.7E-21 T 10-03-2017 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 5.4E-15 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS04200 14303662561815729cd506cb95d39cd6 324 SUPERFAMILY SSF46785 1 85 3.16E-13 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04200 14303662561815729cd506cb95d39cd6 324 Gene3D G3DSA:1.10.10.10 1 81 9.9E-21 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS04200 14303662561815729cd506cb95d39cd6 324 Pfam PF03466 LysR substrate binding domain 92 292 8.0E-43 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS01615 03ae0c2783e02563669bdfa97ca19a67 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 18 121 7.9E-33 T 10-03-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 RG49_RS01615 03ae0c2783e02563669bdfa97ca19a67 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 10-03-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site RG49_RS01615 03ae0c2783e02563669bdfa97ca19a67 122 Gene3D G3DSA:2.60.300.12 18 111 1.0E-28 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS01615 03ae0c2783e02563669bdfa97ca19a67 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 18 118 8.1E-19 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS01615 03ae0c2783e02563669bdfa97ca19a67 122 TIGRFAM TIGR01997 sufA_proteo: FeS assembly scaffold SufA 17 122 1.3E-51 T 10-03-2017 IPR011298 FeS assembly scaffold SufA GO:0016226 RG49_RS01615 03ae0c2783e02563669bdfa97ca19a67 122 SUPERFAMILY SSF89360 18 111 7.46E-27 T 10-03-2017 IPR000361 FeS cluster biogenesis RG49_RS16380 3c610efa1616d180507e6fc253961e25 396 PIRSF PIRSF000138 2 379 5.5E-121 T 10-03-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 RG49_RS16380 3c610efa1616d180507e6fc253961e25 396 Gene3D G3DSA:3.20.20.70 6 376 1.1E-134 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS16380 3c610efa1616d180507e6fc253961e25 396 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 273 279 - T 10-03-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 RG49_RS16380 3c610efa1616d180507e6fc253961e25 396 Hamap MF_01559 L-lactate dehydrogenase [lldD]. 1 380 73.637 T 10-03-2017 IPR020920 L-lactate dehydrogenase, bacterial GO:0004457|GO:0006089|GO:0010181|GO:0055114 RG49_RS16380 3c610efa1616d180507e6fc253961e25 396 SUPERFAMILY SSF51395 6 375 9.16E-100 T 10-03-2017 RG49_RS16380 3c610efa1616d180507e6fc253961e25 396 Pfam PF01070 FMN-dependent dehydrogenase 13 375 2.7E-125 T 10-03-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 RG49_RS12445 0b8803bf4d8ff74f044a00dd494799f8 198 SUPERFAMILY SSF56349 4 184 6.18E-43 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS12445 0b8803bf4d8ff74f044a00dd494799f8 198 Gene3D G3DSA:1.10.443.10 5 174 9.7E-39 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS12445 0b8803bf4d8ff74f044a00dd494799f8 198 Pfam PF00589 Phage integrase family 6 176 3.8E-50 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS12620 c1ce4550f2fd26228902b5e45090e656 138 Pfam PF06877 Regulator of ribonuclease activity B 12 113 1.5E-33 T 10-03-2017 IPR009671 Regulator of ribonuclease activity B domain RG49_RS12620 c1ce4550f2fd26228902b5e45090e656 138 Hamap MF_01888 Regulator of ribonuclease activity B [rraB]. 4 117 31.689 T 10-03-2017 IPR016716 Regulator of ribonuclease activity B RG49_RS12620 c1ce4550f2fd26228902b5e45090e656 138 PIRSF PIRSF018193 1 138 1.4E-67 T 10-03-2017 IPR016716 Regulator of ribonuclease activity B RG49_RS12620 c1ce4550f2fd26228902b5e45090e656 138 Gene3D G3DSA:3.30.70.970 1 124 1.7E-55 T 10-03-2017 IPR009671 Regulator of ribonuclease activity B domain RG49_RS12620 c1ce4550f2fd26228902b5e45090e656 138 SUPERFAMILY SSF89946 2 122 7.45E-43 T 10-03-2017 IPR009671 Regulator of ribonuclease activity B domain RG49_RS18935 88e23865e756e26a93d203bfb46001d7 838 Pfam PF13954 PapC N-terminal domain 44 190 1.6E-45 T 10-03-2017 IPR025885 PapC, N-terminal domain GO:0005515 RG49_RS18935 88e23865e756e26a93d203bfb46001d7 838 SUPERFAMILY SSF141729 71 181 3.01E-30 T 10-03-2017 RG49_RS18935 88e23865e756e26a93d203bfb46001d7 838 Pfam PF00577 Outer membrane usher protein 206 748 1.3E-210 T 10-03-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 RG49_RS18935 88e23865e756e26a93d203bfb46001d7 838 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 317 327 - T 10-03-2017 IPR018030 Fimbrial membrane usher, conserved site RG49_RS18935 88e23865e756e26a93d203bfb46001d7 838 Pfam PF13953 PapC C-terminal domain 757 822 3.1E-20 T 10-03-2017 IPR025949 PapC-like, C-terminal domain RG49_RS21595 dbbc5589e4fed0bf83fb03dea135e004 166 Hamap MF_01114 Regulatory protein RecX [recX]. 6 166 13.532 T 10-03-2017 IPR003783 Regulatory protein RecX GO:0006282 RG49_RS21595 dbbc5589e4fed0bf83fb03dea135e004 166 Pfam PF02631 RecX family 50 162 1.5E-30 T 10-03-2017 IPR003783 Regulatory protein RecX GO:0006282 RG49_RS21595 dbbc5589e4fed0bf83fb03dea135e004 166 Gene3D G3DSA:1.10.10.10 70 115 4.3E-24 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21595 dbbc5589e4fed0bf83fb03dea135e004 166 Gene3D G3DSA:1.10.10.10 116 165 9.8E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS21595 dbbc5589e4fed0bf83fb03dea135e004 166 Gene3D G3DSA:1.10.10.10 13 69 1.2E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS06625 4fb264405b3c7440df80cc25a519c4d8 591 Pfam PF03235 Protein of unknown function DUF262 30 165 2.4E-12 T 10-03-2017 IPR004919 Domain of unknown function DUF262 RG49_RS01570 39fa5572e91d70e9a37bcb40b228ff1b 421 SUPERFAMILY SSF103473 8 391 1.44E-40 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01570 39fa5572e91d70e9a37bcb40b228ff1b 421 Pfam PF07690 Major Facilitator Superfamily 18 334 3.8E-25 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS01570 39fa5572e91d70e9a37bcb40b228ff1b 421 Gene3D G3DSA:1.20.1250.20 15 185 3.8E-17 T 10-03-2017 RG49_RS01570 39fa5572e91d70e9a37bcb40b228ff1b 421 Gene3D G3DSA:1.20.1250.20 218 389 5.6E-13 T 10-03-2017 RG49_RS25250 2b6ccfb8081c3d1fb9e848f324e9303c 417 Pfam PF03611 PTS system sugar-specific permease component 13 377 2.4E-64 T 10-03-2017 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 RG49_RS25250 2b6ccfb8081c3d1fb9e848f324e9303c 417 PIRSF PIRSF006304 4 416 5.4E-121 T 10-03-2017 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 RG49_RS20795 af711b991ec77a5d95991d4ad5733e24 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 195 2.7E-5 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS20795 af711b991ec77a5d95991d4ad5733e24 210 SUPERFAMILY SSF46894 141 195 4.08E-7 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS20795 af711b991ec77a5d95991d4ad5733e24 210 ProDom PD116027 TRANSCRIPTION DNA-BINDING REGULATION RMBA YQEH ORF3-QACEDELTA1 FUSION CYTOPLASMIC ECS3703 TRANSMEMBRANE 12 201 4.0E-111 T 10-03-2017 RG49_RS20795 af711b991ec77a5d95991d4ad5733e24 210 Gene3D G3DSA:1.10.10.10 129 195 1.9E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13130 a20ac7bdc3bd8d10fdca19a53866c7b4 104 ProDom PD069398 YJEN 1 102 2.0E-55 T 10-03-2017 IPR020528 Uncharacterised protein family YjeN RG49_RS23655 f9cf5ef975a24d6cd284ebce2bd80383 220 SUPERFAMILY SSF56770 35 185 2.09E-65 T 10-03-2017 RG49_RS23655 f9cf5ef975a24d6cd284ebce2bd80383 220 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 64 170 3.4E-22 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23655 f9cf5ef975a24d6cd284ebce2bd80383 220 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 144 160 - T 10-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23655 f9cf5ef975a24d6cd284ebce2bd80383 220 Gene3D G3DSA:3.40.50.700 47 174 5.6E-32 T 10-03-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23655 f9cf5ef975a24d6cd284ebce2bd80383 220 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 27 177 42.699 T 10-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS23655 f9cf5ef975a24d6cd284ebce2bd80383 220 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 37 178 8.0E-71 T 10-03-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 Pfam PF03170 Bacterial cellulose synthase subunit 71 680 1.3E-220 T 10-03-2017 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 PRINTS PR01440 Cellulose synthase subunit B signature 100 121 1.8E-32 T 10-03-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 PRINTS PR01440 Cellulose synthase subunit B signature 190 211 1.8E-32 T 10-03-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 PRINTS PR01440 Cellulose synthase subunit B signature 566 586 1.8E-32 T 10-03-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 PRINTS PR01440 Cellulose synthase subunit B signature 232 255 1.8E-32 T 10-03-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 PRINTS PR01440 Cellulose synthase subunit B signature 313 334 1.8E-32 T 10-03-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 PRINTS PR01440 Cellulose synthase subunit B signature 529 548 1.8E-32 T 10-03-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 RG49_RS16855 ac2f1d4b96850d2d0334c65cbaec33cc 779 PRINTS PR01440 Cellulose synthase subunit B signature 396 417 1.8E-32 T 10-03-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 SUPERFAMILY SSF103473 12 443 3.27E-85 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 Pfam PF07690 Major Facilitator Superfamily 34 400 1.1E-44 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 10-03-2017 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-3229133|Reactome: R-HSA-70153 RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 PIRSF PIRSF002808 5 452 3.1E-178 T 10-03-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 439 2.0E-271 T 10-03-2017 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 417 2.8E-170 T 10-03-2017 RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 Gene3D G3DSA:1.20.1250.20 246 448 1.0E-47 T 10-03-2017 RG49_RS23900 8ae7134eced417045f635b16f6b6f407 452 Gene3D G3DSA:1.20.1250.20 21 224 1.1E-54 T 10-03-2017 RG49_RS16665 442cacac4b05bd9bbbd47ce5e97f840e 145 Pfam PF05360 yiaA/B two helix domain 75 127 5.5E-19 T 10-03-2017 IPR008024 YiaAB two helix RG49_RS16665 442cacac4b05bd9bbbd47ce5e97f840e 145 Pfam PF05360 yiaA/B two helix domain 12 64 4.5E-21 T 10-03-2017 IPR008024 YiaAB two helix RG49_RS20520 03a198eccece8086ffbc95c5fb0452a3 192 TIGRFAM TIGR03310 matur_MocA_YgfJ: molybdenum cofactor cytidylyltransferase 5 184 4.0E-64 T 10-03-2017 IPR017696 Molybdenum cofactor cytidylyltransferase MetaCyc: PWY-6476 RG49_RS20520 03a198eccece8086ffbc95c5fb0452a3 192 Gene3D G3DSA:3.90.550.10 1 189 2.0E-29 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS20520 03a198eccece8086ffbc95c5fb0452a3 192 Pfam PF12804 MobA-like NTP transferase domain 6 144 5.2E-25 T 10-03-2017 IPR025877 MobA-like NTP transferase RG49_RS20520 03a198eccece8086ffbc95c5fb0452a3 192 SUPERFAMILY SSF53448 1 189 2.25E-24 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS07265 b44f939266db7350d7326798f5f7f138 250 SUPERFAMILY SSF53254 4 247 5.18E-78 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS07265 b44f939266db7350d7326798f5f7f138 250 SMART SM00855 5 191 2.7E-28 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS07265 b44f939266db7350d7326798f5f7f138 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 125 3.8E-30 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS07265 b44f939266db7350d7326798f5f7f138 250 Gene3D G3DSA:3.40.50.1240 2 250 2.1E-99 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS07265 b44f939266db7350d7326798f5f7f138 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 3 230 46.985 T 10-03-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 RG49_RS07265 b44f939266db7350d7326798f5f7f138 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 10-03-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 RG49_RS07265 b44f939266db7350d7326798f5f7f138 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 5 248 2.3E-130 T 10-03-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 RG49_RS10235 1c91d95f4460201551f95377f316ca32 610 Pfam PF10145 Phage-related minor tail protein 89 296 4.4E-24 T 10-03-2017 IPR010090 Phage tail tape measure protein RG49_RS10235 1c91d95f4460201551f95377f316ca32 610 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 46 405 7.4E-52 T 10-03-2017 IPR010090 Phage tail tape measure protein RG49_RS15680 b30ce09bc7c4b1d35e8b7ca02a233192 24 Pfam PF08053 Tryptophanase operon leader peptide 1 24 2.5E-20 T 10-03-2017 IPR012620 Tryptophanese operon leader peptide GO:0031554|GO:0031556 RG49_RS15680 b30ce09bc7c4b1d35e8b7ca02a233192 24 TIGRFAM TIGR02616 tnaC_leader: tryptophanase leader peptide 3 24 2.8E-12 T 10-03-2017 IPR012620 Tryptophanese operon leader peptide GO:0031554|GO:0031556 RG49_RS12240 773589c99eb37db3113ea2f9c59a6a1b 716 Pfam PF02554 Carbon starvation protein CstA 34 405 1.6E-162 T 10-03-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 RG49_RS12240 773589c99eb37db3113ea2f9c59a6a1b 716 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 487 614 1.6E-34 T 10-03-2017 IPR025299 CstA, C-terminal domain RG49_RS08510 f5d8e143daa551145c79cb12dc0813be 433 Pfam PF00860 Permease family 9 394 5.7E-98 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS07115 96aaeda2e4331957aa280da4475fd18d 161 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 36.996 T 10-03-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 RG49_RS07115 96aaeda2e4331957aa280da4475fd18d 161 Pfam PF01967 MoaC family 15 150 4.7E-55 T 10-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 RG49_RS07115 96aaeda2e4331957aa280da4475fd18d 161 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 2.5E-74 T 10-03-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 RG49_RS07115 96aaeda2e4331957aa280da4475fd18d 161 Gene3D G3DSA:3.30.70.640 3 158 3.5E-70 T 10-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 RG49_RS07115 96aaeda2e4331957aa280da4475fd18d 161 SUPERFAMILY SSF55040 11 155 4.84E-62 T 10-03-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 RG49_RS04005 9b875f158a8efa9d47cded8a23df00bd 73 TIGRFAM TIGR02979 phageshock_pspD: phage shock protein PspD 13 71 8.7E-36 T 10-03-2017 IPR014321 Phage shock protein, PspD RG49_RS04005 9b875f158a8efa9d47cded8a23df00bd 73 Pfam PF09584 Phage shock protein PspD (Phageshock_PspD) 11 71 7.2E-32 T 10-03-2017 IPR014321 Phage shock protein, PspD RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 SUPERFAMILY SSF53448 275 550 3.21E-50 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 199 219 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 227 252 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 363 387 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 593 612 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 524 550 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 667 688 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 282 301 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 PRINTS PR01439 Cellulose synthase subunit A signature 553 572 1.5E-55 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 Pfam PF00535 Glycosyl transferase family 2 276 446 1.1E-34 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 SUPERFAMILY SSF141371 695 779 6.47E-8 T 10-03-2017 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 Pfam PF03552 Cellulose synthase 451 664 1.2E-12 T 10-03-2017 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 Gene3D G3DSA:3.90.550.10 273 507 1.1E-21 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 Pfam PF07238 PilZ domain 694 790 2.6E-12 T 10-03-2017 IPR009875 PilZ domain GO:0035438 RG49_RS16850 3a933a9a1983667b0c9aa7ab83f83c9b 872 TIGRFAM TIGR03030 CelA: cellulose synthase catalytic subunit (UDP-forming) 147 830 0.0 T 10-03-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 RG49_RS05230 862b8f59700949084e6efa63e08d53a6 317 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 141 2.0E-37 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS05230 862b8f59700949084e6efa63e08d53a6 317 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 192 1.3E-72 T 10-03-2017 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 RG49_RS05230 862b8f59700949084e6efa63e08d53a6 317 Gene3D G3DSA:1.20.1330.10 217 260 2.9E-22 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS05230 862b8f59700949084e6efa63e08d53a6 317 Gene3D G3DSA:1.20.1330.10 69 174 2.9E-22 T 10-03-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 RG49_RS05230 862b8f59700949084e6efa63e08d53a6 317 SUPERFAMILY SSF64518 1 315 4.84E-64 T 10-03-2017 RG49_RS03455 e5e1fa100c208076752f8c320925a480 309 SUPERFAMILY SSF47240 27 270 1.89E-81 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS03455 e5e1fa100c208076752f8c320925a480 309 Gene3D G3DSA:1.20.1260.10 17 270 5.4E-102 T 10-03-2017 IPR012347 Ferritin-related RG49_RS03455 e5e1fa100c208076752f8c320925a480 309 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 7 295 2.9E-156 T 10-03-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 RG49_RS03455 e5e1fa100c208076752f8c320925a480 309 Pfam PF05138 Phenylacetic acid catabolic protein 17 291 5.1E-99 T 10-03-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 Gene3D G3DSA:3.40.50.300 3 240 2.8E-63 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 Gene3D G3DSA:3.40.50.300 264 498 8.0E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 SUPERFAMILY SSF52540 4 235 7.29E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 SUPERFAMILY SSF52540 259 504 3.67E-46 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 Pfam PF00005 ABC transporter 21 174 5.2E-31 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 Pfam PF00005 ABC transporter 280 437 3.0E-20 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 SMART SM00382 288 491 0.017 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS13550 d522c72341878ea1cac739ac7c78e2d9 510 SMART SM00382 30 222 8.8E-7 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS02305 0eb93e42ec66cfbe52c551425292377a 250 SUPERFAMILY SSF57938 146 195 8.89E-8 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS02305 0eb93e42ec66cfbe52c551425292377a 250 Pfam PF03589 Antitermination protein 24 107 5.0E-18 T 10-03-2017 IPR003222 Antitermination protein GO:0003677|GO:0006355 RG49_RS02305 0eb93e42ec66cfbe52c551425292377a 250 Pfam PF03589 Antitermination protein 155 242 2.4E-29 T 10-03-2017 IPR003222 Antitermination protein GO:0003677|GO:0006355 RG49_RS02305 0eb93e42ec66cfbe52c551425292377a 250 Gene3D G3DSA:2.10.230.10 109 158 1.2E-5 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS02305 0eb93e42ec66cfbe52c551425292377a 250 Gene3D G3DSA:2.10.230.10 159 193 1.2E-4 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS07515 7c3a1d70f39414d1f77bac45f458803c 348 Pfam PF05145 Putative ammonia monooxygenase 29 339 4.4E-98 T 10-03-2017 IPR007820 AbrB family GO:0010468|GO:0016021 RG49_RS07515 7c3a1d70f39414d1f77bac45f458803c 348 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 6 160 5.0E-41 T 10-03-2017 IPR017516 AbrB duplication RG49_RS07515 7c3a1d70f39414d1f77bac45f458803c 348 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 183 339 5.7E-46 T 10-03-2017 IPR017516 AbrB duplication RG49_RS07515 7c3a1d70f39414d1f77bac45f458803c 348 PIRSF PIRSF038991 1 348 3.0E-100 T 10-03-2017 IPR007820 AbrB family GO:0010468|GO:0016021 RG49_RS17340 73cf2129d481318202345c58426cbd8b 146 ProDom PD059127 YHHA MEMBRANE OUTER PRECURSOR SIGNAL STY4259 ORFQ ECS4294 1 146 2.0E-47 T 10-03-2017 IPR020158 Protein of unknown function DUF2756 RG49_RS17340 73cf2129d481318202345c58426cbd8b 146 Pfam PF10956 Protein of unknown function (DUF2756) 1 105 4.2E-53 T 10-03-2017 IPR020158 Protein of unknown function DUF2756 RG49_RS07280 a649cce1bf695fe53eecc47f52985976 126 ProDom PD079292 YBGS HOMEOBOX PRECURSOR SIGNAL PROBABLE SECRETED 50 126 5.0E-39 T 10-03-2017 IPR020363 Uncharacterised protein family YbgS RG49_RS07280 a649cce1bf695fe53eecc47f52985976 126 Pfam PF13985 YbgS-like protein 3 126 5.1E-55 T 10-03-2017 IPR020363 Uncharacterised protein family YbgS RG49_RS04340 c2a2513cf182628ff57c140f864b2785 417 Gene3D G3DSA:3.40.50.720 242 384 4.3E-32 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS04340 c2a2513cf182628ff57c140f864b2785 417 SUPERFAMILY SSF81324 166 261 9.16E-19 T 10-03-2017 RG49_RS04340 c2a2513cf182628ff57c140f864b2785 417 SUPERFAMILY SSF81324 79 119 9.16E-19 T 10-03-2017 RG49_RS04340 c2a2513cf182628ff57c140f864b2785 417 Pfam PF02254 TrkA-N domain 246 365 7.2E-20 T 10-03-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 RG49_RS04340 c2a2513cf182628ff57c140f864b2785 417 Gene3D G3DSA:1.10.287.70 142 222 1.2E-14 T 10-03-2017 RG49_RS04340 c2a2513cf182628ff57c140f864b2785 417 Pfam PF07885 Ion channel 149 221 2.8E-15 T 10-03-2017 IPR013099 Potassium channel domain RG49_RS04340 c2a2513cf182628ff57c140f864b2785 417 SUPERFAMILY SSF51735 242 384 3.94E-27 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS01970 b2c1e30af19fa40e5767bc8668149a38 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.1E-18 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS01970 b2c1e30af19fa40e5767bc8668149a38 196 SUPERFAMILY SSF48498 84 168 9.93E-12 T 10-03-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal RG49_RS01970 b2c1e30af19fa40e5767bc8668149a38 196 SUPERFAMILY SSF46689 1 79 1.8E-19 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS01970 b2c1e30af19fa40e5767bc8668149a38 196 Gene3D G3DSA:1.10.357.10 5 192 1.7E-35 T 10-03-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 RG49_RS01970 b2c1e30af19fa40e5767bc8668149a38 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 10-03-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site RG49_RS01970 b2c1e30af19fa40e5767bc8668149a38 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-11 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS01970 b2c1e30af19fa40e5767bc8668149a38 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-11 T 10-03-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 Gene3D G3DSA:3.90.79.10 12 156 2.1E-28 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 10-03-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 Pfam PF00293 NUDIX domain 18 154 1.5E-17 T 10-03-2017 IPR000086 NUDIX hydrolase domain GO:0016787 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 PRINTS PR01404 DATP pyrophosphohydrolase signature 84 103 1.4E-55 T 10-03-2017 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 PRINTS PR01404 DATP pyrophosphohydrolase signature 112 133 1.4E-55 T 10-03-2017 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 PRINTS PR01404 DATP pyrophosphohydrolase signature 33 54 1.4E-55 T 10-03-2017 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 PRINTS PR01404 DATP pyrophosphohydrolase signature 16 33 1.4E-55 T 10-03-2017 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 PRINTS PR01404 DATP pyrophosphohydrolase signature 139 152 1.4E-55 T 10-03-2017 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 RG49_RS00590 887a130a0315ac542e24ffa3a5a30394 160 SUPERFAMILY SSF55811 15 154 6.5E-23 T 10-03-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 RG49_RS09065 38a74cb1c9ac64e2eec5a461bd6814cf 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 1.9E-78 T 10-03-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 RG49_RS09065 38a74cb1c9ac64e2eec5a461bd6814cf 149 Pfam PF03477 ATP cone domain 50 136 2.6E-15 T 10-03-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 RG49_RS09065 38a74cb1c9ac64e2eec5a461bd6814cf 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 89.122 T 10-03-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 RG49_RS10660 4549ff22f4fa8316d5e7f53edc5ed397 350 TIGRFAM TIGR03354 VI_FHA: type VI secretion system FHA domain protein 11 342 1.7E-83 T 10-03-2017 IPR017735 Type VI secretion system, FHA domain-containing protein RG49_RS05675 1dcd6d92651c44a7234a28522f3bf66b 57 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 32 52 9.2E-10 T 10-03-2017 IPR019626 Stress-induced protein, KGG, repeat RG49_RS05675 1dcd6d92651c44a7234a28522f3bf66b 57 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 10 30 1.8E-9 T 10-03-2017 IPR019626 Stress-induced protein, KGG, repeat RG49_RS11855 a7351cee907051f06cd7882c81dd0eac 258 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 38.405 T 10-03-2017 IPR005583 Peroxide stress protein YaaA RG49_RS11855 a7351cee907051f06cd7882c81dd0eac 258 Pfam PF03883 Protein of unknown function (DUF328) 1 243 2.3E-91 T 10-03-2017 IPR005583 Peroxide stress protein YaaA RG49_RS10215 39207ba513f07fa7b7206154436bcbee 182 PIRSF PIRSF012337 1 182 1.4E-58 T 10-03-2017 IPR014462 Phage-associated protein Gp45 RG49_RS10215 39207ba513f07fa7b7206154436bcbee 182 TIGRFAM TIGR01644 phage_P2_V: phage baseplate assembly protein V 8 129 1.5E-14 T 10-03-2017 IPR013046 Phage baseplate assembly protein V/Gp45 RG49_RS10215 39207ba513f07fa7b7206154436bcbee 182 Pfam PF06890 Bacteriophage Mu Gp45 protein 16 164 2.7E-47 T 10-03-2017 IPR014462 Phage-associated protein Gp45 RG49_RS03440 dd2f272e4c07d2e5c190093f163c8329 165 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 22 165 8.0E-73 T 10-03-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit RG49_RS03440 dd2f272e4c07d2e5c190093f163c8329 165 Pfam PF01883 Domain of unknown function DUF59 14 74 5.5E-10 T 10-03-2017 IPR002744 Domain of unknown function DUF59 RG49_RS03440 dd2f272e4c07d2e5c190093f163c8329 165 SUPERFAMILY SSF117916 12 105 7.52E-23 T 10-03-2017 RG49_RS10525 3caff59624c34f172e9f2b104efce56b 261 Gene3D G3DSA:3.30.1330.60 116 222 7.0E-17 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS10525 3caff59624c34f172e9f2b104efce56b 261 SUPERFAMILY SSF103088 106 222 3.01E-18 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS10525 3caff59624c34f172e9f2b104efce56b 261 Pfam PF00691 OmpA family 120 212 1.4E-14 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 5.3E-11 T 10-03-2017 RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 5.3E-11 T 10-03-2017 RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 265 280 5.3E-11 T 10-03-2017 RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 SUPERFAMILY SSF51905 3 168 8.34E-29 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 SUPERFAMILY SSF51905 251 309 8.34E-29 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 Gene3D G3DSA:3.50.50.60 1 171 5.0E-20 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 Gene3D G3DSA:3.50.50.60 263 293 5.0E-20 T 10-03-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 RG49_RS15775 24c754e6ced7d1ca99c5e30203fa19d2 354 Pfam PF01494 FAD binding domain 135 166 1.7E-5 T 10-03-2017 IPR002938 FAD-binding domain GO:0071949 RG49_RS14375 f86a7e80cdbf5542a6dee4efc45dc61d 359 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 10 335 5.8E-90 T 10-03-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 RG49_RS07000 6d9c657173835d3007724c52251fab67 760 Gene3D G3DSA:2.170.130.10 33 179 4.6E-32 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS07000 6d9c657173835d3007724c52251fab67 760 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 168 3.2E-19 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS07000 6d9c657173835d3007724c52251fab67 760 SUPERFAMILY SSF56935 32 760 3.21E-122 T 10-03-2017 RG49_RS07000 6d9c657173835d3007724c52251fab67 760 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 70 760 1.6E-77 T 10-03-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 RG49_RS07000 6d9c657173835d3007724c52251fab67 760 Pfam PF00593 TonB dependent receptor 514 758 1.9E-34 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS07000 6d9c657173835d3007724c52251fab67 760 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 49 - T 10-03-2017 IPR010916 TonB box, conserved site RG49_RS07000 6d9c657173835d3007724c52251fab67 760 Gene3D G3DSA:2.40.170.20 185 760 3.5E-146 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS14770 69519cebcaa9a4f149ff58a43cbd38cd 413 Hamap MF_00998 Sulfoquinovose isomerase. 1 413 83.464 T 10-03-2017 IPR030875 Sulfoquinovose isomerase GO:0061593 MetaCyc: PWY-7446 RG49_RS14770 69519cebcaa9a4f149ff58a43cbd38cd 413 Gene3D G3DSA:1.50.10.10 2 393 8.7E-100 T 10-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 RG49_RS14770 69519cebcaa9a4f149ff58a43cbd38cd 413 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 32 387 4.8E-132 T 10-03-2017 RG49_RS14770 69519cebcaa9a4f149ff58a43cbd38cd 413 SUPERFAMILY SSF48208 3 409 1.36E-115 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 163 171 - T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 Pfam PF13505 Outer membrane protein beta-barrel domain 9 171 3.7E-23 T 10-03-2017 IPR027385 Outer membrane protein beta-barrel RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 SUPERFAMILY SSF56925 27 171 2.62E-34 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 Gene3D G3DSA:2.40.160.20 26 171 2.4E-46 T 10-03-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 132 153 1.7E-39 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 159 170 1.7E-39 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 85 108 1.7E-39 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 45 57 1.7E-39 T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS06935 1f42062652e327a66a7fccdab455504e 171 ProSitePatterns PS00694 Enterobacterial virulence outer membrane protein signature 1. 46 54 - T 10-03-2017 IPR000758 Virulence-related outer membrane protein GO:0009279 RG49_RS20195 73340d20313520da6931f65a511eadf0 43 ProDom PD050163 YQGB INNER MEMBRANE STY3241 1 39 2.0E-16 T 10-03-2017 IPR020196 Uncharacterised protein family YqgB RG49_RS20195 73340d20313520da6931f65a511eadf0 43 Pfam PF11036 Virulence promoting factor 1 43 2.8E-33 T 10-03-2017 IPR020196 Uncharacterised protein family YqgB RG49_RS06930 40d4e1ed75e2940532daedd454bd6801 527 Pfam PF00884 Sulfatase 217 483 9.6E-44 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS06930 40d4e1ed75e2940532daedd454bd6801 527 SUPERFAMILY SSF53649 220 487 8.29E-20 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS06930 40d4e1ed75e2940532daedd454bd6801 527 Gene3D G3DSA:3.40.720.10 220 486 6.8E-13 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS19130 a330b1b5749d3a06929053f127e08624 443 Hamap MF_01583 Threonine/serine transporter TdcC [tdcC]. 1 443 55.698 T 10-03-2017 IPR023726 Threonine/serine transporter TdcC GO:0015565|GO:0015826|GO:0016021|GO:0022889|GO:0032329 RG49_RS19130 a330b1b5749d3a06929053f127e08624 443 Pfam PF03222 Tryptophan/tyrosine permease family 29 438 3.2E-8 T 10-03-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 RG49_RS19130 a330b1b5749d3a06929053f127e08624 443 TIGRFAM TIGR00814 stp: serine transporter 17 433 3.9E-173 T 10-03-2017 IPR004694 Hydroxy amino acid transporter GO:0005215|GO:0006810|GO:0016021 RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 168 186 - T 10-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 250 1.8E-114 T 10-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 Pfam PF00557 Metallopeptidase family M24 12 242 6.1E-54 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 6.1E-24 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 162 174 6.1E-24 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 92 108 6.1E-24 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 6.1E-24 T 10-03-2017 IPR001714 Peptidase M24, methionine aminopeptidase RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 Hamap MF_01974 Methionine aminopeptidase [map]. 3 251 44.081 T 10-03-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 SUPERFAMILY SSF55920 3 255 4.32E-93 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS10985 c168653e3c8d2bb35f52032fea2ce506 264 Gene3D G3DSA:3.90.230.10 3 259 1.5E-102 T 10-03-2017 IPR000994 Peptidase M24, structural domain RG49_RS16590 435247bb3f3f6beec598421ffe52c9ee 417 SUPERFAMILY SSF53383 26 411 2.06E-58 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS16590 435247bb3f3f6beec598421ffe52c9ee 417 Pfam PF00155 Aminotransferase class I and II 69 391 4.7E-21 T 10-03-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 RG49_RS16590 435247bb3f3f6beec598421ffe52c9ee 417 Gene3D G3DSA:3.90.1150.10 267 410 7.3E-16 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS16590 435247bb3f3f6beec598421ffe52c9ee 417 Gene3D G3DSA:3.40.640.10 61 266 2.3E-39 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS22020 1c1cb437efd7b028aed534728d4005d3 121 Pfam PF10973 Protein of unknown function (DUF2799) 32 111 3.3E-17 T 10-03-2017 IPR021242 Protein of unknown function DUF2799 RG49_RS15635 cc4c025526dd4ed554c2fe772486b49e 155 ProDom PD092472 YIEI MEMBRANE INNER TRANSMEMBRANE 1 144 3.0E-75 T 10-03-2017 IPR020222 Inner membrane CbrB GO:0016021 RG49_RS24705 395bb8e25584aae67594f809cb99fd17 424 TIGRFAM TIGR00897 2A0118: polyol permease 1 406 1.5E-188 T 10-03-2017 IPR004748 Polyol permease GO:0005215|GO:0006810|GO:0016021 RG49_RS24705 395bb8e25584aae67594f809cb99fd17 424 SUPERFAMILY SSF103473 6 411 1.7E-44 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS24705 395bb8e25584aae67594f809cb99fd17 424 Gene3D G3DSA:1.20.1250.20 222 409 4.0E-21 T 10-03-2017 RG49_RS24705 395bb8e25584aae67594f809cb99fd17 424 Pfam PF07690 Major Facilitator Superfamily 25 342 5.2E-20 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS24705 395bb8e25584aae67594f809cb99fd17 424 Gene3D G3DSA:1.20.1250.20 15 197 4.6E-15 T 10-03-2017 RG49_RS00805 b89972f7b70346a6ffd6915ae7d9e200 293 Hamap MF_00188 Protease HtpX [htpX]. 1 289 27.11 T 10-03-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 RG49_RS00805 b89972f7b70346a6ffd6915ae7d9e200 293 Pfam PF01435 Peptidase family M48 73 288 3.1E-39 T 10-03-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 RG49_RS00805 b89972f7b70346a6ffd6915ae7d9e200 293 Gene3D G3DSA:3.30.2010.10 69 156 4.4E-32 T 10-03-2017 RG49_RS03760 a27d6e58ae9e9237b6d05da3bd361194 58 Pfam PF04181 Rtr1/RPAP2 family 8 54 6.6E-6 T 10-03-2017 IPR007308 Protein of unknown function DUF408 KEGG: 04660+3.1.3.16|Reactome: R-HSA-6807505 RG49_RS08980 8404e23b100d4aba614871681fcc1a72 204 Pfam PF00510 Cytochrome c oxidase subunit III 16 202 1.7E-15 T 10-03-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08980 8404e23b100d4aba614871681fcc1a72 204 SUPERFAMILY SSF81452 12 202 1.7E-59 T 10-03-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS08980 8404e23b100d4aba614871681fcc1a72 204 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 25 204 2.6E-88 T 10-03-2017 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 RG49_RS08980 8404e23b100d4aba614871681fcc1a72 204 Gene3D G3DSA:1.20.120.80 26 202 1.7E-51 T 10-03-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 Gene3D G3DSA:1.10.10.10 133 195 1.4E-22 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 2.1E-12 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 2.1E-12 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 2.1E-12 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 2.2E-21 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 SUPERFAMILY SSF46894 134 196 6.12E-19 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 Gene3D G3DSA:3.40.50.2300 1 120 2.7E-4 T 10-03-2017 RG49_RS16930 ac797bbc1012fe9e3a1d90be39c0f000 200 SMART SM00421 139 196 5.8E-22 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS02345 9039280c2ef1ddd72dc2b3d08bc9d04e 165 Pfam PF10721 Protein of unknown function (DUF2514) 5 159 4.8E-37 T 10-03-2017 IPR019659 Protein of unknown function DUF2514 RG49_RS18895 5f6ff897400e90b230e3132fadc227a3 211 SMART SM00859 3 103 0.0096 T 10-03-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 RG49_RS18895 5f6ff897400e90b230e3132fadc227a3 211 Pfam PF13460 NAD(P)H-binding 8 188 8.3E-10 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18895 5f6ff897400e90b230e3132fadc227a3 211 Gene3D G3DSA:3.40.50.720 2 208 9.6E-45 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS18895 5f6ff897400e90b230e3132fadc227a3 211 SUPERFAMILY SSF51735 2 200 1.9E-40 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 Gene3D G3DSA:2.40.50.140 5 68 3.2E-32 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 SMART SM00357 6 70 2.5E-31 T 10-03-2017 IPR011129 Cold shock protein GO:0003676 RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 PIRSF PIRSF002599 1 70 1.1E-25 T 10-03-2017 IPR012156 Cold shock, CspA GO:0003676 RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 PRINTS PR00050 Cold shock protein signature 7 22 5.8E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 PRINTS PR00050 Cold shock protein signature 28 37 5.8E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 PRINTS PR00050 Cold shock protein signature 43 61 5.8E-18 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 SUPERFAMILY SSF50249 4 69 3.94E-26 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 8.6E-33 T 10-03-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 RG49_RS16705 40785a8282413070fe126dfd41e458ff 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 10-03-2017 IPR019844 Cold-shock conserved site RG49_RS20245 db4473ddc1449778e483d62bf50e6406 237 Gene3D G3DSA:3.40.50.300 6 230 9.6E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20245 db4473ddc1449778e483d62bf50e6406 237 SUPERFAMILY SSF52540 25 220 4.49E-28 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 Gene3D G3DSA:2.40.50.100 208 241 3.0E-17 T 10-03-2017 RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 Gene3D G3DSA:2.40.50.100 48 81 3.0E-17 T 10-03-2017 RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 Pfam PF13533 Biotin-lipoyl like 49 96 1.2E-16 T 10-03-2017 RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 SUPERFAMILY SSF111369 182 297 1.7E-9 T 10-03-2017 RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 SUPERFAMILY SSF111369 117 171 6.67E-5 T 10-03-2017 RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 TIGRFAM TIGR00998 8a0101: efflux pump membrane protein 10 340 1.9E-126 T 10-03-2017 IPR005694 Efflux pump membrane protein Emr GO:0006855|GO:0015238 RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 Pfam PF13437 HlyD family secretion protein 210 293 1.6E-12 T 10-03-2017 RG49_RS13580 d2f4c2d153851a199c26a184e332e674 343 SUPERFAMILY SSF111369 45 102 6.93E-13 T 10-03-2017 RG49_RS03630 85d2d15b7144964ad6e515a4353915cc 124 Gene3D G3DSA:3.30.1150.10 27 123 5.3E-31 T 10-03-2017 RG49_RS03630 85d2d15b7144964ad6e515a4353915cc 124 Pfam PF06519 TolA C-terminal 38 118 1.1E-14 T 10-03-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 RG49_RS03630 85d2d15b7144964ad6e515a4353915cc 124 SUPERFAMILY SSF74653 38 121 2.55E-15 T 10-03-2017 RG49_RS12585 8a3198a08c3043736c517d2711479048 366 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 348 5.5E-116 T 10-03-2017 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 RG49_RS12585 8a3198a08c3043736c517d2711479048 366 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 345 2.3E-72 T 10-03-2017 IPR005495 Permease LptG/LptF-related GO:0016021 RG49_RS15240 57545119ea045da1671ae8663a816de5 450 Hamap MF_01003 Probable ECA polymerase [wzyE]. 1 448 43.134 T 10-03-2017 IPR010691 Probable ECA polymerase WzyE GO:0009246|GO:0016021 RG49_RS15240 57545119ea045da1671ae8663a816de5 450 Pfam PF06899 WzyE protein, O-antigen assembly polymerase 1 446 1.9E-263 T 10-03-2017 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 Pfam PF00330 Aconitase family (aconitate hydratase) 41 470 3.7E-75 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 Gene3D G3DSA:3.30.499.10 348 531 6.9E-35 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 Gene3D G3DSA:3.30.499.10 301 314 6.9E-35 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 Gene3D G3DSA:3.30.499.10 29 185 7.5E-32 T 10-03-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 Gene3D G3DSA:3.40.1060.10 187 292 1.5E-20 T 10-03-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 PRINTS PR00415 Aconitase family signature 297 311 5.5E-6 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 PRINTS PR00415 Aconitase family signature 356 367 5.5E-6 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 PRINTS PR00415 Aconitase family signature 140 153 5.5E-6 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 PRINTS PR00415 Aconitase family signature 413 426 5.5E-6 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 PRINTS PR00415 Aconitase family signature 216 229 5.5E-6 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 SUPERFAMILY SSF53732 18 509 4.19E-115 T 10-03-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 Pfam PF00694 Aconitase C-terminal domain 636 683 4.1E-6 T 10-03-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 Gene3D G3DSA:3.20.19.10 532 752 2.9E-47 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS07180 6a396a78209cd015940d1535e5abb1e7 753 SUPERFAMILY SSF52016 516 751 1.35E-33 T 10-03-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel RG49_RS17210 2177f81e6b305ed683dc7fe8a2b8e1d5 185 Pfam PF08786 Domain of unknown function (DUF1795) 51 181 2.0E-29 T 10-03-2017 IPR014894 Protein DcrB RG49_RS17210 2177f81e6b305ed683dc7fe8a2b8e1d5 185 Gene3D G3DSA:3.40.1000.10 52 183 3.7E-4 T 10-03-2017 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:1.20.1580.10 251 284 5.6E-54 T 10-03-2017 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:1.20.1580.10 407 477 5.6E-54 T 10-03-2017 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:1.20.1580.10 91 129 5.6E-54 T 10-03-2017 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 SUPERFAMILY SSF52540 613 911 2.9E-54 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13735 1c7ba006096828fb01e4325187699247 940 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 SUPERFAMILY SSF52540 433 569 1.57E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13735 1c7ba006096828fb01e4325187699247 940 SUPERFAMILY SSF52540 4 204 1.57E-43 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:3.30.1490.20 130 153 4.9E-28 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:3.30.1490.20 200 249 4.9E-28 T 10-03-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:1.10.8.280 286 406 5.5E-44 T 10-03-2017 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Pfam PF00005 ABC transporter 806 860 1.1E-5 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:1.20.1580.10 694 820 3.0E-54 T 10-03-2017 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 925 0.0 T 10-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:3.40.50.300 821 938 4.8E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:3.40.50.300 2 51 1.2E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:3.40.50.300 478 599 1.2E-53 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Gene3D G3DSA:3.40.50.300 603 692 4.8E-58 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13735 1c7ba006096828fb01e4325187699247 940 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 940 23.231 T 10-03-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 RG49_RS05860 876dc3992dc25108fa8cc0e9b1bc8d16 219 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 213 1.5E-42 T 10-03-2017 RG49_RS05860 876dc3992dc25108fa8cc0e9b1bc8d16 219 ProSitePatterns PS01243 Bax inhibitor-1 family signature. 87 117 - T 10-03-2017 IPR006213 Bax inhibitor 1, conserved site GO:0016021|GO:0043066 RG49_RS10500 f613e41dec45d915f6caee2f3429ce03 88 SUPERFAMILY SSF103365 8 73 4.18E-13 T 10-03-2017 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 RG49_RS02865 36a9a4610ce76e5efc5008059008fecd 466 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 16 448 4.3E-209 T 10-03-2017 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 RG49_RS02865 36a9a4610ce76e5efc5008059008fecd 466 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 269 290 - T 10-03-2017 IPR021115 Pyridoxal-phosphate binding site GO:0016831 RG49_RS02865 36a9a4610ce76e5efc5008059008fecd 466 SUPERFAMILY SSF53383 6 451 1.09E-132 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS02865 36a9a4610ce76e5efc5008059008fecd 466 Gene3D G3DSA:3.40.640.10 75 321 2.0E-24 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS02865 36a9a4610ce76e5efc5008059008fecd 466 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 33 383 1.5E-114 T 10-03-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 RG49_RS03215 d63693131045d2fc316fad652ac29efd 145 Pfam PF01381 Helix-turn-helix 95 141 3.9E-7 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS03215 d63693131045d2fc316fad652ac29efd 145 Gene3D G3DSA:1.10.260.40 95 142 7.6E-6 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS03215 d63693131045d2fc316fad652ac29efd 145 SMART SM00530 88 143 4.7E-4 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS03215 d63693131045d2fc316fad652ac29efd 145 SUPERFAMILY SSF47413 89 143 9.65E-6 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS03215 d63693131045d2fc316fad652ac29efd 145 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 10 74 2.2E-7 T 10-03-2017 IPR031807 HicB-like antitoxin of toxin-antitoxin system RG49_RS03215 d63693131045d2fc316fad652ac29efd 145 SUPERFAMILY SSF143100 7 71 3.01E-16 T 10-03-2017 RG49_RS05435 44dc230543a37dd5c81a67cabbeaf14d 110 PIRSF PIRSF018100 1 110 1.8E-70 T 10-03-2017 IPR014491 Curli production protein CsgC RG49_RS05435 44dc230543a37dd5c81a67cabbeaf14d 110 Pfam PF10610 Thin aggregative fimbriae synthesis protein 6 103 3.1E-50 T 10-03-2017 IPR014491 Curli production protein CsgC RG49_RS22585 88c18222cb76a6c2e734489f794a9681 144 SMART SM00530 73 129 5.0E-4 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS22585 88c18222cb76a6c2e734489f794a9681 144 SUPERFAMILY SSF47413 71 143 5.04E-17 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS22585 88c18222cb76a6c2e734489f794a9681 144 Pfam PF01381 Helix-turn-helix 77 128 7.1E-7 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS22585 88c18222cb76a6c2e734489f794a9681 144 Gene3D G3DSA:1.10.260.40 60 143 3.1E-21 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS22585 88c18222cb76a6c2e734489f794a9681 144 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 67 142 1.6E-19 T 10-03-2017 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 RG49_RS01520 31070fcc3c8c3b9ffcdef104433a1bf9 97 SUPERFAMILY SSF54862 42 91 2.82E-8 T 10-03-2017 RG49_RS01520 31070fcc3c8c3b9ffcdef104433a1bf9 97 PIRSF PIRSF036548 3 97 3.5E-37 T 10-03-2017 IPR012206 Ferredoxin-like, FixX GO:0005506 RG49_RS01520 31070fcc3c8c3b9ffcdef104433a1bf9 97 Gene3D G3DSA:3.30.70.20 42 81 9.0E-6 T 10-03-2017 RG49_RS01520 31070fcc3c8c3b9ffcdef104433a1bf9 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS05705 ea9c872e77944385518df5f5ae7feaab 101 Hamap MF_01155 Chaperone modulatory protein CbpM [cbpM]. 1 97 24.732 T 10-03-2017 IPR022835 Chaperone modulatory protein CbpM RG49_RS05705 ea9c872e77944385518df5f5ae7feaab 101 Pfam PF13591 MerR HTH family regulatory protein 8 92 2.9E-27 T 10-03-2017 RG49_RS15035 4b2854ef28a7ae4768468e32e4e24cb2 253 Pfam PF01048 Phosphorylase superfamily 21 246 1.1E-40 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS15035 4b2854ef28a7ae4768468e32e4e24cb2 253 Gene3D G3DSA:3.40.50.1580 5 252 7.4E-85 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS15035 4b2854ef28a7ae4768468e32e4e24cb2 253 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 66 81 - T 10-03-2017 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 RG49_RS15035 4b2854ef28a7ae4768468e32e4e24cb2 253 SUPERFAMILY SSF53167 6 250 4.58E-73 T 10-03-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 RG49_RS15035 4b2854ef28a7ae4768468e32e4e24cb2 253 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 6 253 1.5E-132 T 10-03-2017 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3 RG49_RS00270 299ed0a2bda94e80264dded64e65fdd9 136 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 129 3.7E-57 T 10-03-2017 IPR003713 Flagellar protein FliS GO:0044780 RG49_RS00270 299ed0a2bda94e80264dded64e65fdd9 136 Gene3D G3DSA:1.20.120.340 9 124 7.2E-38 T 10-03-2017 IPR003713 Flagellar protein FliS GO:0044780 RG49_RS00270 299ed0a2bda94e80264dded64e65fdd9 136 PIRSF PIRSF039090 1 135 1.3E-43 T 10-03-2017 IPR003713 Flagellar protein FliS GO:0044780 RG49_RS00270 299ed0a2bda94e80264dded64e65fdd9 136 SUPERFAMILY SSF101116 9 124 6.41E-34 T 10-03-2017 IPR003713 Flagellar protein FliS GO:0044780 RG49_RS00270 299ed0a2bda94e80264dded64e65fdd9 136 Pfam PF02561 Flagellar protein FliS 8 124 3.9E-34 T 10-03-2017 IPR003713 Flagellar protein FliS GO:0044780 RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 PIRSF PIRSF005572 2 384 1.9E-144 T 10-03-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 Gene3D G3DSA:3.90.1150.10 255 375 2.1E-52 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 2.5E-236 T 10-03-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 SUPERFAMILY SSF53383 5 391 4.52E-117 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 Gene3D G3DSA:3.40.640.10 17 254 3.7E-99 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 Pfam PF00266 Aminotransferase class-V 5 368 1.3E-89 T 10-03-2017 IPR000192 Aminotransferase class V domain RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 10-03-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site RG49_RS22420 858f1fe35d5f51a75188c72882269fe8 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 56.355 T 10-03-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 RG49_RS05355 e8a7f3a1191b80e840fc13ba4a5b87ef 46 Pfam PF10968 Protein of unknown function (DUF2770) 10 45 4.1E-20 T 10-03-2017 IPR024494 Protein of unknown function DUF2770 RG49_RS05355 e8a7f3a1191b80e840fc13ba4a5b87ef 46 ProDom PD049682 YCEO INNER MEMBRANE STY1197 10 46 4.0E-13 T 10-03-2017 IPR024494 Protein of unknown function DUF2770 RG49_RS21750 da81aa9bbb8eab8ccc5fbc5789024777 174 SUPERFAMILY SSF52821 2 154 1.44E-24 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS21750 da81aa9bbb8eab8ccc5fbc5789024777 174 Pfam PF00581 Rhodanese-like domain 7 99 6.6E-10 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS21750 da81aa9bbb8eab8ccc5fbc5789024777 174 Pfam PF11127 Protein of unknown function (DUF2892) 115 171 1.0E-10 T 10-03-2017 IPR021309 Protein of unknown function DUF2892 RG49_RS21750 da81aa9bbb8eab8ccc5fbc5789024777 174 Gene3D G3DSA:3.40.250.10 4 107 2.6E-18 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS21750 da81aa9bbb8eab8ccc5fbc5789024777 174 SMART SM00450 6 102 2.7E-14 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS07510 9566b8f3a0a026d643af5844c71f5d96 353 Gene3D G3DSA:2.60.40.1090 218 353 5.7E-6 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS07510 9566b8f3a0a026d643af5844c71f5d96 353 Pfam PF00419 Fimbrial protein 217 352 9.1E-8 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS07510 9566b8f3a0a026d643af5844c71f5d96 353 SUPERFAMILY SSF49401 217 353 3.98E-8 T 10-03-2017 IPR008966 Adhesion domain RG49_RS23630 c76d5062861d24b3c113f7ddbf8a0690 199 SMART SM00471 26 151 1.6E-7 T 10-03-2017 IPR003607 HD/PDEase domain RG49_RS23630 c76d5062861d24b3c113f7ddbf8a0690 199 Hamap MF_01100 5'-deoxynucleotidase YfbR [yfbR]. 3 195 43.709 T 10-03-2017 IPR022971 5'-deoxynucleotidase YfbR KEGG: 00240+3.1.3.89 RG49_RS23630 c76d5062861d24b3c113f7ddbf8a0690 199 SUPERFAMILY SSF109604 2 193 4.57E-45 T 10-03-2017 RG49_RS23630 c76d5062861d24b3c113f7ddbf8a0690 199 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 80 172 4.0E-48 T 10-03-2017 RG49_RS23630 c76d5062861d24b3c113f7ddbf8a0690 199 Pfam PF13023 HD domain 11 160 6.9E-17 T 10-03-2017 IPR006674 HD domain RG49_RS23630 c76d5062861d24b3c113f7ddbf8a0690 199 Gene3D G3DSA:1.10.3210.10 2 194 2.8E-53 T 10-03-2017 IPR006674 HD domain RG49_RS02440 c50af477a8f7e0721fde5a28fabb3c01 1021 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 811 885 7.9E-22 T 10-03-2017 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal RG49_RS02440 c50af477a8f7e0721fde5a28fabb3c01 1021 TIGRFAM TIGR01541 tape_meas_lam_C: phage tail tape measure protein, lambda family 656 981 2.7E-85 T 10-03-2017 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal RG49_RS02440 c50af477a8f7e0721fde5a28fabb3c01 1021 Pfam PF06791 Prophage tail length tape measure protein 228 426 1.1E-51 T 10-03-2017 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal RG49_RS04095 8363268fa7b8ab3c96eca838750c1a4c 330 Gene3D G3DSA:3.40.50.300 2 260 2.6E-57 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04095 8363268fa7b8ab3c96eca838750c1a4c 330 SUPERFAMILY SSF52540 3 264 3.03E-51 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS04095 8363268fa7b8ab3c96eca838750c1a4c 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 1.9E-20 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS04095 8363268fa7b8ab3c96eca838750c1a4c 330 SMART SM00382 32 235 2.5E-5 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS04095 8363268fa7b8ab3c96eca838750c1a4c 330 Pfam PF00005 ABC transporter 24 187 1.4E-27 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS04095 8363268fa7b8ab3c96eca838750c1a4c 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 305 7.1E-17 T 10-03-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 SUPERFAMILY SSF52172 1 125 2.28E-39 T 10-03-2017 IPR011006 CheY-like superfamily RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 Gene3D G3DSA:3.40.50.2300 1 120 5.3E-39 T 10-03-2017 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 SMART SM00448 1 111 6.5E-43 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 218 2.9E-115 T 10-03-2017 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 1.9E-24 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 SUPERFAMILY SSF46894 117 219 1.87E-27 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 SMART SM00862 143 218 4.4E-23 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 Pfam PF00072 Response regulator receiver domain 3 112 1.1E-26 T 10-03-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 RG49_RS00045 3be66e34ffa1b2f6d41641c651c4fb06 223 Gene3D G3DSA:1.10.10.10 123 219 4.9E-29 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS15130 cd9da0cb6e8b5fa40b63fb915baf0b61 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 207 8.8E-14 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15130 cd9da0cb6e8b5fa40b63fb915baf0b61 238 Gene3D G3DSA:3.40.50.1000 10 236 7.9E-29 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15130 cd9da0cb6e8b5fa40b63fb915baf0b61 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 199 3.6E-11 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS15130 cd9da0cb6e8b5fa40b63fb915baf0b61 238 SUPERFAMILY SSF56784 10 238 1.53E-39 T 10-03-2017 IPR023214 HAD-like domain RG49_RS18710 3a22854b60f2d397294992484f1a8b31 103 SUPERFAMILY SSF141091 1 102 4.45E-37 T 10-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18710 3a22854b60f2d397294992484f1a8b31 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.783 T 10-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18710 3a22854b60f2d397294992484f1a8b31 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 10-03-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 RG49_RS18710 3a22854b60f2d397294992484f1a8b31 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.1E-37 T 10-03-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS18710 3a22854b60f2d397294992484f1a8b31 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 3.3E-45 T 10-03-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 RG49_RS05440 6104f627c19aca2b8622e0d66701df0a 151 Pfam PF07012 Curlin associated repeat 86 119 1.4E-9 T 10-03-2017 IPR009742 Curlin associated GO:0007155|GO:0009289 RG49_RS05440 6104f627c19aca2b8622e0d66701df0a 151 Pfam PF07012 Curlin associated repeat 108 141 3.4E-6 T 10-03-2017 IPR009742 Curlin associated GO:0007155|GO:0009289 RG49_RS05440 6104f627c19aca2b8622e0d66701df0a 151 Pfam PF07012 Curlin associated repeat 40 74 1.2E-8 T 10-03-2017 IPR009742 Curlin associated GO:0007155|GO:0009289 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 PRINTS PR01374 Gram-negative bacterial tonB protein signature 176 194 3.1E-39 T 10-03-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 PRINTS PR01374 Gram-negative bacterial tonB protein signature 195 212 3.1E-39 T 10-03-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 PRINTS PR01374 Gram-negative bacterial tonB protein signature 155 176 3.1E-39 T 10-03-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 PRINTS PR01374 Gram-negative bacterial tonB protein signature 91 101 3.1E-39 T 10-03-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 161 233 1.2E-20 T 10-03-2017 IPR006260 TonB, C-terminal GO:0006810 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 Gene3D G3DSA:3.30.1150.10 135 234 5.0E-13 T 10-03-2017 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 SUPERFAMILY SSF74653 153 222 1.7E-21 T 10-03-2017 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 160 227 1.9E-18 T 10-03-2017 IPR006260 TonB, C-terminal GO:0006810 RG49_RS04330 610fa5ce85b9c5d1af3d09847b9f8959 239 Pfam PF16031 TonB N-terminal region 33 157 1.2E-35 T 10-03-2017 RG49_RS20300 73ab7404676a644bb2cc33b95892cb53 331 Gene3D G3DSA:1.20.5.170 4 54 7.3E-19 T 10-03-2017 RG49_RS20300 73ab7404676a644bb2cc33b95892cb53 331 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 323 1.8E-137 T 10-03-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 RG49_RS20300 73ab7404676a644bb2cc33b95892cb53 331 Gene3D G3DSA:1.10.287.130 263 331 4.0E-39 T 10-03-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 RG49_RS20300 73ab7404676a644bb2cc33b95892cb53 331 SUPERFAMILY SSF52540 5 321 3.64E-90 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS20300 73ab7404676a644bb2cc33b95892cb53 331 Pfam PF03308 ArgK protein 22 294 8.7E-119 T 10-03-2017 RG49_RS20300 73ab7404676a644bb2cc33b95892cb53 331 Gene3D G3DSA:3.40.50.300 55 258 2.0E-47 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS16470 6b00b958be2be86533dc0bbb3ca02f26 314 PRINTS PR00394 RHS protein signature 4 23 1.6E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS16470 6b00b958be2be86533dc0bbb3ca02f26 314 PRINTS PR00394 RHS protein signature 120 139 1.6E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS16470 6b00b958be2be86533dc0bbb3ca02f26 314 PRINTS PR00394 RHS protein signature 97 117 1.6E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS16470 6b00b958be2be86533dc0bbb3ca02f26 314 PRINTS PR00394 RHS protein signature 73 88 1.6E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS16470 6b00b958be2be86533dc0bbb3ca02f26 314 PRINTS PR00394 RHS protein signature 42 62 1.6E-57 T 10-03-2017 IPR001826 RHS protein RG49_RS16470 6b00b958be2be86533dc0bbb3ca02f26 314 Pfam PF03527 RHS protein 48 82 2.9E-14 T 10-03-2017 IPR001826 RHS protein RG49_RS16470 6b00b958be2be86533dc0bbb3ca02f26 314 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 75 152 1.2E-24 T 10-03-2017 IPR022385 Rhs repeat-associated core GO:0097264 RG49_RS23380 bc7bf55eca457e7f3382f1100b079077 161 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 71 1.4E-7 T 10-03-2017 IPR013078 Histidine phosphatase superfamily, clade-1 RG49_RS23380 bc7bf55eca457e7f3382f1100b079077 161 SUPERFAMILY SSF53254 1 143 1.41E-18 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS23380 bc7bf55eca457e7f3382f1100b079077 161 Gene3D G3DSA:3.40.50.1240 1 157 5.1E-43 T 10-03-2017 IPR029033 Histidine phosphatase superfamily RG49_RS23380 bc7bf55eca457e7f3382f1100b079077 161 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 152 5.6E-66 T 10-03-2017 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 RG49_RS24340 ff6629194d9c7fd986f9c2a0ea968072 232 SUPERFAMILY SSF51206 17 138 9.17E-21 T 10-03-2017 IPR018490 Cyclic nucleotide-binding-like RG49_RS24340 ff6629194d9c7fd986f9c2a0ea968072 232 Gene3D G3DSA:2.60.120.10 19 139 4.3E-19 T 10-03-2017 IPR014710 RmlC-like jelly roll fold RG49_RS24340 ff6629194d9c7fd986f9c2a0ea968072 232 Pfam PF00027 Cyclic nucleotide-binding domain 35 118 1.0E-12 T 10-03-2017 IPR000595 Cyclic nucleotide-binding domain RG49_RS24340 ff6629194d9c7fd986f9c2a0ea968072 232 SMART SM00100 15 133 1.6E-18 T 10-03-2017 IPR000595 Cyclic nucleotide-binding domain RG49_RS22600 c6a1c4301b3b4257dba92fcfb4709e56 392 SMART SM00974 278 372 1.5E-19 T 10-03-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding RG49_RS22600 c6a1c4301b3b4257dba92fcfb4709e56 392 Pfam PF10544 T5orf172 domain 262 372 1.9E-12 T 10-03-2017 IPR018306 Bacteriophage T5, Orf172 DNA-binding RG49_RS19840 d3f872f6275962a61c7099e106f9d8b7 252 Gene3D G3DSA:3.40.50.300 23 240 3.4E-16 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19840 d3f872f6275962a61c7099e106f9d8b7 252 SUPERFAMILY SSF52540 23 47 1.02E-9 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19840 d3f872f6275962a61c7099e106f9d8b7 252 SUPERFAMILY SSF52540 96 226 1.02E-9 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS23085 c556e29794117f257152eefec0fd446e 332 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 8 316 1.2E-103 T 10-03-2017 IPR016833 Putative sodium bile acid cotransporter RG49_RS23085 c556e29794117f257152eefec0fd446e 332 PIRSF PIRSF026166 1 332 1.5E-136 T 10-03-2017 IPR016833 Putative sodium bile acid cotransporter RG49_RS23805 2ceb787818d4a72477ec32d5f728d3fb 111 Hamap MF_01869 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE [arnE]. 1 111 28.503 T 10-03-2017 IPR022883 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase, subunit ArnE RG49_RS23805 2ceb787818d4a72477ec32d5f728d3fb 111 Pfam PF00892 EamA-like transporter family 3 107 7.6E-10 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS23805 2ceb787818d4a72477ec32d5f728d3fb 111 SUPERFAMILY SSF103481 5 107 1.27E-15 T 10-03-2017 RG49_RS03505 70ae7df1b964c15eb97ff2db11c457d1 88 Pfam PF03891 Domain of unknown function (DUF333) 38 83 2.5E-15 T 10-03-2017 IPR005590 Protein of unknown function DUF333 RG49_RS22735 610946c1e49db3658be5403446824b1e 315 Pfam PF00146 NADH dehydrogenase 18 311 8.6E-54 T 10-03-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22735 610946c1e49db3658be5403446824b1e 315 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 201 214 - T 10-03-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS06570 8b126bab52cf619bca164024a6e9cd17 171 TIGRFAM TIGR01611 tail_tube: phage major tail tube protein 3 171 5.3E-50 T 10-03-2017 IPR006498 Tail tube protein RG49_RS06570 8b126bab52cf619bca164024a6e9cd17 171 Pfam PF04985 Phage tail tube protein FII 4 170 1.2E-60 T 10-03-2017 IPR006498 Tail tube protein RG49_RS15580 c7c808e23ee95b56cd60bc41c96f9abb 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 289 1.8E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS15580 c7c808e23ee95b56cd60bc41c96f9abb 296 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 28 293 2.4E-85 T 10-03-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 RG49_RS15580 c7c808e23ee95b56cd60bc41c96f9abb 296 SUPERFAMILY SSF161098 35 286 2.62E-32 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS15580 c7c808e23ee95b56cd60bc41c96f9abb 296 Gene3D G3DSA:1.10.3720.10 27 295 1.1E-37 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13850 9a861c9d3337fb01351fc4e3aefedb58 431 Gene3D G3DSA:3.80.10.10 209 235 3.4E-4 T 10-03-2017 IPR032675 Leucine-rich repeat domain, L domain-like RG49_RS13850 9a861c9d3337fb01351fc4e3aefedb58 431 Gene3D G3DSA:3.80.10.10 10 140 3.4E-4 T 10-03-2017 IPR032675 Leucine-rich repeat domain, L domain-like RG49_RS13850 9a861c9d3337fb01351fc4e3aefedb58 431 Pfam PF13599 Pentapeptide repeats (9 copies) 98 164 8.6E-8 T 10-03-2017 IPR001646 Pentapeptide repeat RG49_RS13850 9a861c9d3337fb01351fc4e3aefedb58 431 SUPERFAMILY SSF141571 9 158 4.91E-22 T 10-03-2017 RG49_RS13850 9a861c9d3337fb01351fc4e3aefedb58 431 Pfam PF13981 SopA-like central domain 198 330 8.7E-53 T 10-03-2017 IPR025726 E3 ubiquitin ligase SopA-like central domain RG49_RS18885 0275d594d49c1f6c3d8cdb5b1e06f89f 147 SUPERFAMILY SSF50475 7 140 1.57E-13 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS18885 0275d594d49c1f6c3d8cdb5b1e06f89f 147 Hamap MF_00764 UPF0306 protein YhbP [yhbP]. 3 140 36.042 T 10-03-2017 IPR011194 Uncharacterised protein family UPF0306 RG49_RS18885 0275d594d49c1f6c3d8cdb5b1e06f89f 147 PIRSF PIRSF009554 1 145 2.3E-62 T 10-03-2017 IPR011194 Uncharacterised protein family UPF0306 RG49_RS18885 0275d594d49c1f6c3d8cdb5b1e06f89f 147 Gene3D G3DSA:2.30.110.10 28 139 7.7E-6 T 10-03-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 RG49_RS16120 f54b4ac02d6862e1b67a49108a92661b 569 Pfam PF05170 AsmA family 1 523 7.7E-26 T 10-03-2017 IPR007844 AsmA RG49_RS03780 8c74262c9ecc9135d3835e591c5354d5 64 TIGRFAM TIGR03655 anti_R_Lar: restriction alleviation protein, Lar family 6 54 1.7E-15 T 10-03-2017 IPR019908 Restriction alleviation protein, Lar RG49_RS03780 8c74262c9ecc9135d3835e591c5354d5 64 Pfam PF14354 Restriction alleviation protein Lar 5 54 3.6E-11 T 10-03-2017 RG49_RS09300 acc9eed688beb3f8038958e540bd5175 255 SUPERFAMILY SSF52540 1 212 8.24E-66 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09300 acc9eed688beb3f8038958e540bd5175 255 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 10-03-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 RG49_RS09300 acc9eed688beb3f8038958e540bd5175 255 Gene3D G3DSA:3.40.50.300 1 210 2.6E-64 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS09300 acc9eed688beb3f8038958e540bd5175 255 SMART SM00382 26 205 1.2E-16 T 10-03-2017 IPR003593 AAA+ ATPase domain RG49_RS09300 acc9eed688beb3f8038958e540bd5175 255 Pfam PF00005 ABC transporter 17 156 3.6E-32 T 10-03-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 RG49_RS06655 90e94fbcde2f9876e989ce93e379b406 71 Pfam PF16080 Bacteriophage holin family HP1 5 56 4.2E-10 T 10-03-2017 IPR032118 Bacteriophage holin HP1 family RG49_RS00870 48ceeff369173479995acd1316efe884 283 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 11 281 3.0E-150 T 10-03-2017 IPR018405 Phosphotransferase system, mannose/fructose/sorbose family IID component, subgroup GO:0009401|GO:0016021 RG49_RS00870 48ceeff369173479995acd1316efe884 283 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 12 281 2.5E-111 T 10-03-2017 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 RG49_RS23555 76ed7ed45f8dc1f280dd497d5ce3c6b7 296 Pfam PF04754 Putative transposase, YhgA-like 8 209 4.0E-88 T 10-03-2017 IPR006842 Transposase (putative), YhgA-like RG49_RS23555 76ed7ed45f8dc1f280dd497d5ce3c6b7 296 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 291 1.8E-55 T 10-03-2017 IPR010106 Conserved hypothetical protein CHP01784 RG49_RS17150 6c702897ef8c9556ac210c1b8b619da7 81 Gene3D G3DSA:1.25.10.10 7 81 1.1E-5 T 10-03-2017 IPR011989 Armadillo-like helical RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 Gene3D G3DSA:2.30.30.60 933 982 1.3E-16 T 10-03-2017 RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 SUPERFAMILY SSF82861 834 916 1.7E-8 T 10-03-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 Pfam PF00924 Mechanosensitive ion channel 875 1074 8.8E-54 T 10-03-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 478 814 7.0E-117 T 10-03-2017 IPR025692 Mechanosensitive ion channel inner membrane domain 1 RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 SUPERFAMILY SSF82689 985 1083 3.4E-16 T 10-03-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 Pfam PF12795 Mechanosensitive ion channel porin domain 31 256 1.2E-54 T 10-03-2017 IPR024393 Mechanosensitive ion channel MscS, porin domain RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 Gene3D G3DSA:3.30.70.100 989 1072 6.6E-8 T 10-03-2017 RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 947 981 - T 10-03-2017 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 RG49_RS13120 cfddd8b5fec36e360530d9439c71c973 1107 SUPERFAMILY SSF50182 918 983 7.52E-17 T 10-03-2017 IPR010920 LSM domain RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 Gene3D G3DSA:3.30.1600.10 149 193 1.3E-26 T 10-03-2017 IPR026591 Sirtuin family, catalytic core small domain RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 Gene3D G3DSA:3.30.1600.10 57 96 1.3E-26 T 10-03-2017 IPR026591 Sirtuin family, catalytic core small domain RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 Gene3D G3DSA:3.40.50.1220 106 148 1.5E-41 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 Gene3D G3DSA:3.40.50.1220 200 266 1.5E-41 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 Gene3D G3DSA:3.40.50.1220 39 56 1.5E-41 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 SUPERFAMILY SSF52467 41 270 1.39E-74 T 10-03-2017 IPR029035 DHS-like NAD/FAD-binding domain RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 Pfam PF02146 Sir2 family 48 221 9.3E-51 T 10-03-2017 IPR003000 Sirtuin family GO:0070403 RG49_RS05035 1372b353a2cb6c6fb538d2def86c7cfc 279 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 41 271 63.2 T 10-03-2017 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 RG49_RS16140 4adc569f0aefe88b64aeed76bccea176 229 Pfam PF12105 SpoU, rRNA methylase, C-terminal 163 218 1.2E-24 T 10-03-2017 IPR022724 RNA methyltransferase, SpoU/TrmH type, C-terminal GO:0009020 RG49_RS16140 4adc569f0aefe88b64aeed76bccea176 229 Pfam PF00588 SpoU rRNA Methylase family 20 159 1.2E-36 T 10-03-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 RG49_RS16140 4adc569f0aefe88b64aeed76bccea176 229 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 2 197 36.859 T 10-03-2017 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 RG49_RS16140 4adc569f0aefe88b64aeed76bccea176 229 SUPERFAMILY SSF75217 4 174 7.85E-50 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS16140 4adc569f0aefe88b64aeed76bccea176 229 Gene3D G3DSA:3.40.1280.10 2 174 1.4E-49 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS05260 7094f4fdab69cee2c4307a73117a0697 251 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 120 2.2E-32 T 10-03-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G RG49_RS05260 7094f4fdab69cee2c4307a73117a0697 251 Pfam PF00460 Flagella basal body rod protein 5 35 2.0E-10 T 10-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 RG49_RS05260 7094f4fdab69cee2c4307a73117a0697 251 SUPERFAMILY SSF117143 77 209 2.35E-16 T 10-03-2017 RG49_RS05260 7094f4fdab69cee2c4307a73117a0697 251 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 10-03-2017 IPR019776 Flagellar basal body rod protein, conserved site RG49_RS05260 7094f4fdab69cee2c4307a73117a0697 251 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 170 247 1.6E-20 T 10-03-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain RG49_RS22005 01810fdaf7e82a4eab1431799e66d066 160 Pfam PF00691 OmpA family 55 151 5.8E-19 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS22005 01810fdaf7e82a4eab1431799e66d066 160 Gene3D G3DSA:3.30.1330.60 46 158 6.7E-30 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS22005 01810fdaf7e82a4eab1431799e66d066 160 SUPERFAMILY SSF103088 45 157 1.83E-28 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS22005 01810fdaf7e82a4eab1431799e66d066 160 PRINTS PR01021 OMPA domain signature 86 101 9.1E-11 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS22005 01810fdaf7e82a4eab1431799e66d066 160 PRINTS PR01021 OMPA domain signature 101 117 9.1E-11 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS22005 01810fdaf7e82a4eab1431799e66d066 160 PRINTS PR01021 OMPA domain signature 56 78 9.1E-11 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS09320 5d0c799343be7f7695ba09dab5c34e63 398 SUPERFAMILY SSF53448 32 289 1.58E-43 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS09320 5d0c799343be7f7695ba09dab5c34e63 398 Pfam PF00535 Glycosyl transferase family 2 34 198 1.8E-24 T 10-03-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 RG49_RS09320 5d0c799343be7f7695ba09dab5c34e63 398 Gene3D G3DSA:3.90.550.10 35 260 3.4E-28 T 10-03-2017 IPR029044 Nucleotide-diphospho-sugar transferases RG49_RS21830 cff7f9af52865eecfde5dd3f5e39c6cb 263 ProDom PD114157 YPJB ECS3517 1 223 9.0E-128 T 10-03-2017 IPR020228 Uncharacterised protein family, YpjB RG49_RS20155 cdd5f9cab8a3311b675752041f458eed 243 Pfam PF04452 RNA methyltransferase 20 236 1.1E-73 T 10-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS20155 cdd5f9cab8a3311b675752041f458eed 243 Gene3D G3DSA:2.40.240.20 1 71 2.1E-30 T 10-03-2017 RG49_RS20155 cdd5f9cab8a3311b675752041f458eed 243 PIRSF PIRSF015601 2 242 8.6E-52 T 10-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS20155 cdd5f9cab8a3311b675752041f458eed 243 SUPERFAMILY SSF88697 2 70 4.22E-18 T 10-03-2017 IPR015947 PUA-like domain RG49_RS20155 cdd5f9cab8a3311b675752041f458eed 243 SUPERFAMILY SSF75217 75 242 2.35E-51 T 10-03-2017 IPR029028 Alpha/beta knot methyltransferases RG49_RS20155 cdd5f9cab8a3311b675752041f458eed 243 Gene3D G3DSA:3.40.1280.10 75 242 8.0E-59 T 10-03-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal RG49_RS20155 cdd5f9cab8a3311b675752041f458eed 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 242 2.0E-95 T 10-03-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 RG49_RS23965 87c184b108863c4d6edd0988a251856e 562 Pfam PF09909 Uncharacterized protein conserved in bacteria (DUF2138) 16 559 1.6E-243 T 10-03-2017 IPR018671 Protein of unknown function DUF2138 RG49_RS06650 97d1b21d4893915e7cf80a5a61c92b65 170 Gene3D G3DSA:1.10.530.40 29 168 2.0E-57 T 10-03-2017 IPR023347 Lysozyme domain GO:0003796 RG49_RS06650 97d1b21d4893915e7cf80a5a61c92b65 170 Pfam PF00959 Phage lysozyme 54 160 1.1E-20 T 10-03-2017 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 RG49_RS06650 97d1b21d4893915e7cf80a5a61c92b65 170 SUPERFAMILY SSF53955 11 168 3.02E-56 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS10560 99472ffcb58487c5aaf42e057c101ab1 246 Gene3D G3DSA:2.40.440.10 43 159 4.9E-5 T 10-03-2017 RG49_RS10560 99472ffcb58487c5aaf42e057c101ab1 246 Pfam PF03734 L,D-transpeptidase catalytic domain 45 159 2.5E-6 T 10-03-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 RG49_RS10560 99472ffcb58487c5aaf42e057c101ab1 246 SUPERFAMILY SSF141523 42 159 1.83E-10 T 10-03-2017 RG49_RS19605 f69c64219e2f9f7854c82b7c6d5a6bc7 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 87 1.3E-28 T 10-03-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain RG49_RS19605 f69c64219e2f9f7854c82b7c6d5a6bc7 104 Gene3D G3DSA:3.30.70.900 1 102 2.0E-40 T 10-03-2017 RG49_RS19605 f69c64219e2f9f7854c82b7c6d5a6bc7 104 SUPERFAMILY SSF54909 1 100 1.61E-30 T 10-03-2017 IPR011008 Dimeric alpha-beta barrel RG49_RS22390 d2e7d0b083eaf00e77aaa538711b503e 379 SUPERFAMILY SSF103473 7 371 1.44E-35 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS22390 d2e7d0b083eaf00e77aaa538711b503e 379 TIGRFAM TIGR00902 2A0127: MFS transporter, phenyl propionate permease (PPP) family 1 379 4.5E-214 T 10-03-2017 IPR026032 Probable 3-phenylpropionic acid transporter RG49_RS22390 d2e7d0b083eaf00e77aaa538711b503e 379 Pfam PF12832 MFS_1 like family 8 358 1.8E-44 T 10-03-2017 IPR024989 Major facilitator superfamily associated domain RG49_RS22390 d2e7d0b083eaf00e77aaa538711b503e 379 Gene3D G3DSA:1.20.1250.20 8 182 3.8E-15 T 10-03-2017 RG49_RS22390 d2e7d0b083eaf00e77aaa538711b503e 379 Gene3D G3DSA:1.20.1250.20 204 371 3.9E-20 T 10-03-2017 RG49_RS22390 d2e7d0b083eaf00e77aaa538711b503e 379 PIRSF PIRSF004925 1 379 2.2E-121 T 10-03-2017 IPR026032 Probable 3-phenylpropionic acid transporter RG49_RS10295 0ebd36f0bef7e0681aff5a150a14710a 216 Pfam PF04586 Caudovirus prohead serine protease 12 160 7.3E-34 T 10-03-2017 IPR006433 Prohead protease RG49_RS10295 0ebd36f0bef7e0681aff5a150a14710a 216 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 20 159 4.6E-47 T 10-03-2017 IPR006433 Prohead protease RG49_RS10295 0ebd36f0bef7e0681aff5a150a14710a 216 SUPERFAMILY SSF50789 24 145 2.11E-5 T 10-03-2017 RG49_RS00440 1446729bec3da4ae5a0b090583def8a9 474 SUPERFAMILY SSF53756 2 455 1.67E-148 T 10-03-2017 RG49_RS00440 1446729bec3da4ae5a0b090583def8a9 474 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 453 4.9E-184 T 10-03-2017 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 RG49_RS00440 1446729bec3da4ae5a0b090583def8a9 474 Pfam PF00982 Glycosyltransferase family 20 17 452 9.7E-153 T 10-03-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 RG49_RS00440 1446729bec3da4ae5a0b090583def8a9 474 Gene3D G3DSA:3.40.50.2000 1 239 1.6E-74 T 10-03-2017 RG49_RS00440 1446729bec3da4ae5a0b090583def8a9 474 Gene3D G3DSA:3.40.50.2000 244 435 1.4E-75 T 10-03-2017 RG49_RS10670 dee19294acfb2c0ed86a5c81683d66df 443 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 6 442 7.7E-161 T 10-03-2017 IPR010263 Type VI secretion protein, VC_A0114 RG49_RS10670 dee19294acfb2c0ed86a5c81683d66df 443 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 20 441 6.8E-141 T 10-03-2017 IPR010263 Type VI secretion protein, VC_A0114 RG49_RS18780 ac3c12043664c960a42ed3727ffe91ab 541 Gene3D G3DSA:3.40.720.10 226 462 4.6E-11 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS18780 ac3c12043664c960a42ed3727ffe91ab 541 Pfam PF00884 Sulfatase 224 462 2.7E-43 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS18780 ac3c12043664c960a42ed3727ffe91ab 541 SUPERFAMILY SSF53649 226 463 8.97E-22 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS16760 df841a9ecb8bd49056c65c4ec0caa48d 563 SUPERFAMILY SSF53649 250 542 4.86E-20 T 10-03-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 RG49_RS16760 df841a9ecb8bd49056c65c4ec0caa48d 563 Gene3D G3DSA:3.40.720.10 250 543 3.6E-15 T 10-03-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 RG49_RS16760 df841a9ecb8bd49056c65c4ec0caa48d 563 Pfam PF00884 Sulfatase 250 538 2.6E-50 T 10-03-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 RG49_RS16760 df841a9ecb8bd49056c65c4ec0caa48d 563 Pfam PF08019 Domain of unknown function (DUF1705) 57 172 1.4E-18 T 10-03-2017 IPR012549 Domain of unknown function DUF1705 GO:0016021 RG49_RS17645 0dfcf6395bb5dd0ff6266aebdd8e8c93 428 Gene3D G3DSA:3.30.70.1070 343 407 4.6E-5 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS17645 0dfcf6395bb5dd0ff6266aebdd8e8c93 428 Hamap MF_02021 Cell division protein DamX [damX]. 1 428 25.175 T 10-03-2017 IPR032899 Cell division protein DamX GO:0030428|GO:0032506 RG49_RS17645 0dfcf6395bb5dd0ff6266aebdd8e8c93 428 Pfam PF05036 Sporulation related domain 345 417 1.3E-12 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS17645 0dfcf6395bb5dd0ff6266aebdd8e8c93 428 SUPERFAMILY SSF110997 344 408 4.45E-7 T 10-03-2017 IPR007730 Sporulation-related domain GO:0042834 RG49_RS13685 2c87aa08ee2ab8b82c0df6ec510cff2c 449 Pfam PF00860 Permease family 26 409 1.8E-88 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS05000 d85b3bfd79fc3d04d5b29c206f3b0408 153 Pfam PF12158 Protein of unknown function (DUF3592) 7 138 1.9E-15 T 10-03-2017 IPR021994 Protein of unknown function DUF3592 RG49_RS06815 06492c649ddc5b0e81a734de36500f67 208 SUPERFAMILY SSF52833 1 85 4.35E-23 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS06815 06492c649ddc5b0e81a734de36500f67 208 Gene3D G3DSA:1.20.1050.10 84 203 1.8E-30 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS06815 06492c649ddc5b0e81a734de36500f67 208 Gene3D G3DSA:3.40.30.10 1 82 4.5E-24 T 10-03-2017 IPR012336 Thioredoxin-like fold RG49_RS06815 06492c649ddc5b0e81a734de36500f67 208 SUPERFAMILY SSF47616 84 203 2.23E-28 T 10-03-2017 IPR010987 Glutathione S-transferase, C-terminal-like RG49_RS06815 06492c649ddc5b0e81a734de36500f67 208 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 3.2E-14 T 10-03-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 RG49_RS06815 06492c649ddc5b0e81a734de36500f67 208 Pfam PF00043 Glutathione S-transferase, C-terminal domain 121 197 3.3E-11 T 10-03-2017 IPR004046 Glutathione S-transferase, C-terminal RG49_RS05400 27f676681a6362b462ec3b4fcb0ed417 75 Pfam PF07119 Protein of unknown function (DUF1375) 9 69 8.1E-10 T 10-03-2017 IPR010780 Protein of unknown function DUF1375 RG49_RS15185 270d43e4c5d4965a1f3abd51031515a7 403 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 34 363 4.5E-136 T 10-03-2017 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX RG49_RS02555 7fb0fd3693bc8cf386058d0e2854a238 299 SUPERFAMILY SSF103481 206 287 6.02E-8 T 10-03-2017 RG49_RS02555 7fb0fd3693bc8cf386058d0e2854a238 299 Pfam PF00892 EamA-like transporter family 7 130 7.6E-14 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS02555 7fb0fd3693bc8cf386058d0e2854a238 299 Pfam PF00892 EamA-like transporter family 143 286 1.5E-14 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS02555 7fb0fd3693bc8cf386058d0e2854a238 299 SUPERFAMILY SSF103481 42 132 3.4E-11 T 10-03-2017 RG49_RS24500 05bcd88239388b81b3c7bc16da507672 204 Pfam PF09335 SNARE associated Golgi protein 35 155 1.6E-16 T 10-03-2017 IPR032816 SNARE associated Golgi protein RG49_RS10330 612002100f9a4b56e4251bd4b4263488 130 Pfam PF10828 Protein of unknown function (DUF2570) 9 109 3.5E-9 T 10-03-2017 IPR022538 Protein of unknown function DUF2570 RG49_RS20855 1026896290f734e7d904f3ba74bc8838 397 SUPERFAMILY SSF103473 16 396 3.4E-21 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS20855 1026896290f734e7d904f3ba74bc8838 397 Pfam PF07690 Major Facilitator Superfamily 20 354 3.7E-13 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS20855 1026896290f734e7d904f3ba74bc8838 397 Hamap MF_01585 Lysophospholipid transporter LplT [lplT]. 1 397 39.4 T 10-03-2017 IPR023727 Lysophospholipid transporter LplT GO:0005886|GO:0051977|GO:0051978 RG49_RS20855 1026896290f734e7d904f3ba74bc8838 397 Gene3D G3DSA:1.20.1250.20 18 185 8.2E-10 T 10-03-2017 RG49_RS22965 cdcea2e903168b78e3f87e53f7d17c13 191 Gene3D G3DSA:2.60.460.10 26 191 2.6E-84 T 10-03-2017 RG49_RS22965 cdcea2e903168b78e3f87e53f7d17c13 191 ProDom PD105195 LIPOPROTEIN YFEY MEMBRANE OUTER PRECURSOR SIGNAL ESCHERICHIA ECS3303 EXPORTED Y1456 1 191 2.0E-110 T 10-03-2017 IPR010938 Protein of unknown function DUF1131 RG49_RS22965 cdcea2e903168b78e3f87e53f7d17c13 191 Pfam PF06572 Protein of unknown function (DUF1131) 24 191 3.4E-82 T 10-03-2017 IPR010938 Protein of unknown function DUF1131 RG49_RS15630 f27f9784c59d8e932ddce32a6ca24d98 195 Pfam PF03691 Uncharacterised protein family (UPF0167) 8 194 7.6E-70 T 10-03-2017 IPR005363 Uncharacterised protein family UPF0167 RG49_RS03775 0e3806be9fca91c6b4790d9dbd9ca089 269 Pfam PF03837 RecT family 53 244 4.8E-57 T 10-03-2017 IPR018330 RecT family GO:0003677|GO:0006259 RG49_RS03775 0e3806be9fca91c6b4790d9dbd9ca089 269 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 1 243 1.8E-125 T 10-03-2017 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 RG49_RS11180 f8c2a3bed8a22a88dff6e7b5ed82af79 300 Pfam PF04754 Putative transposase, YhgA-like 7 207 6.8E-85 T 10-03-2017 IPR006842 Transposase (putative), YhgA-like RG49_RS11180 f8c2a3bed8a22a88dff6e7b5ed82af79 300 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 8 296 1.6E-89 T 10-03-2017 IPR010106 Conserved hypothetical protein CHP01784 RG49_RS20690 6c87f3d84d0471d4b9d7406aff6aa4b1 244 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 74 87 1.8E-13 T 10-03-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 RG49_RS20690 6c87f3d84d0471d4b9d7406aff6aa4b1 244 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 22 32 1.8E-13 T 10-03-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 RG49_RS20690 6c87f3d84d0471d4b9d7406aff6aa4b1 244 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 114 127 1.8E-13 T 10-03-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 RG49_RS20690 6c87f3d84d0471d4b9d7406aff6aa4b1 244 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 94 109 1.8E-13 T 10-03-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 RG49_RS20690 6c87f3d84d0471d4b9d7406aff6aa4b1 244 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 163 175 1.8E-13 T 10-03-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 RG49_RS20690 6c87f3d84d0471d4b9d7406aff6aa4b1 244 Pfam PF01514 Secretory protein of YscJ/FliF family 6 187 5.8E-15 T 10-03-2017 IPR006182 Secretory protein YscJ/FliF RG49_RS20690 6c87f3d84d0471d4b9d7406aff6aa4b1 244 TIGRFAM TIGR02544 III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family 3 190 1.9E-65 T 10-03-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 RG49_RS17235 7cee527f7c119ddd36f97f62295d0fcb 119 Pfam PF10694 Protein of unknown function (DUF2500) 5 115 2.8E-31 T 10-03-2017 IPR019635 Protein of unknown function DUF2500 RG49_RS04405 9d35196a4b2b4391e41badc99dc3fb4c 166 Pfam PF01609 Transposase DDE domain 21 134 9.4E-9 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS02125 6a4f85ec825b46f3ad6fe6e5135ea3db 284 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 274 1.0E-115 T 10-03-2017 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 RG49_RS06245 a8dd2fdb990fc46d1b3ec00200b5dd8d 382 Pfam PF07690 Major Facilitator Superfamily 12 227 3.5E-14 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS06245 a8dd2fdb990fc46d1b3ec00200b5dd8d 382 Gene3D G3DSA:1.20.1250.20 208 372 1.0E-16 T 10-03-2017 RG49_RS06245 a8dd2fdb990fc46d1b3ec00200b5dd8d 382 Gene3D G3DSA:1.20.1250.20 8 184 3.1E-20 T 10-03-2017 RG49_RS06245 a8dd2fdb990fc46d1b3ec00200b5dd8d 382 Hamap MF_01149 Uncharacterized MFS-type transporter YcaD [ycaD]. 1 382 40.488 T 10-03-2017 IPR023745 MSF-type transporter, YcaD RG49_RS06245 a8dd2fdb990fc46d1b3ec00200b5dd8d 382 SUPERFAMILY SSF103473 8 376 1.57E-44 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS16235 dd6481bef3d12aad924e892d84a04e7f 425 Pfam PF00534 Glycosyl transferases group 1 240 398 1.1E-11 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS16235 dd6481bef3d12aad924e892d84a04e7f 425 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 33 211 1.8E-67 T 10-03-2017 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 RG49_RS16235 dd6481bef3d12aad924e892d84a04e7f 425 SUPERFAMILY SSF53756 57 420 2.06E-19 T 10-03-2017 RG49_RS04605 6a0f28f7a21cfc27f20df0b8b89ec6ec 92 Pfam PF10762 Protein of unknown function (DUF2583) 1 87 6.1E-47 T 10-03-2017 IPR019698 Protein of unknown function DUF2583 RG49_RS19640 51c113056902e5b919dcadc144985608 98 Pfam PF15723 Motility quorum-sensing regulator, toxin of MqsA 5 97 4.0E-32 T 10-03-2017 IPR031451 mRNA interferase MqsR GO:0009372|GO:0017148|GO:0042710 RG49_RS21645 7366776f3790ebe26119d479341fb788 142 Pfam PF09335 SNARE associated Golgi protein 26 131 4.5E-10 T 10-03-2017 IPR032816 SNARE associated Golgi protein RG49_RS07075 d0c938714fedc9b781bf354ec1a5aaf0 136 Pfam PF11076 Putative inner membrane protein YbhQ 1 132 8.4E-71 T 10-03-2017 IPR021303 Uncharacterised protein family, inner membrane, YbhQ RG49_RS02845 23330dd331dafb332dcbcd0c9344a149 790 SUPERFAMILY SSF56935 217 790 1.6E-51 T 10-03-2017 RG49_RS02845 23330dd331dafb332dcbcd0c9344a149 790 SUPERFAMILY SSF56935 31 187 1.6E-51 T 10-03-2017 RG49_RS02845 23330dd331dafb332dcbcd0c9344a149 790 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 165 1.4E-8 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS02845 23330dd331dafb332dcbcd0c9344a149 790 Gene3D G3DSA:2.170.130.10 47 165 1.3E-5 T 10-03-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 RG49_RS02845 23330dd331dafb332dcbcd0c9344a149 790 Gene3D G3DSA:2.40.170.20 166 175 3.2E-33 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS02845 23330dd331dafb332dcbcd0c9344a149 790 Gene3D G3DSA:2.40.170.20 217 790 3.2E-33 T 10-03-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 RG49_RS12485 5773838e5e36fca771b85d7313d20546 290 Pfam PF13391 HNH endonuclease 182 236 1.4E-6 T 10-03-2017 IPR003615 HNH nuclease RG49_RS12485 5773838e5e36fca771b85d7313d20546 290 PIRSF PIRSF030850 1 290 2.8E-145 T 10-03-2017 IPR011396 Uncharacterised conserved protein UCP030850 RG49_RS03795 d2605bdeb8ee028ac7427d2ce6a32823 411 Pfam PF12167 Domain of unknown function (DUF3596) 5 69 5.8E-25 T 10-03-2017 IPR022000 Domain of unknown function (DUF3596) RG49_RS03795 d2605bdeb8ee028ac7427d2ce6a32823 411 Gene3D G3DSA:1.10.443.10 200 403 1.9E-37 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS03795 d2605bdeb8ee028ac7427d2ce6a32823 411 Pfam PF00589 Phage integrase family 203 391 3.8E-23 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS03795 d2605bdeb8ee028ac7427d2ce6a32823 411 SUPERFAMILY SSF56349 82 400 5.21E-53 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS03795 d2605bdeb8ee028ac7427d2ce6a32823 411 Gene3D G3DSA:1.10.150.130 82 193 5.0E-9 T 10-03-2017 IPR023109 Integrase/recombinase, N-terminal RG49_RS16670 24a9a6f693fb27ea4dd299486ff6398b 331 Hamap MF_01949 O-acetyltransferase WecH [wecH]. 1 331 38.396 T 10-03-2017 IPR032905 O-acetyltransferase WecH GO:0009246|GO:0016413 RG49_RS16670 24a9a6f693fb27ea4dd299486ff6398b 331 Pfam PF01757 Acyltransferase family 5 318 3.2E-35 T 10-03-2017 IPR002656 Acyltransferase 3 GO:0016747 RG49_RS19300 46394d8005da3d75cb3a9c4665a02bdc 138 Pfam PF01381 Helix-turn-helix 84 135 4.3E-7 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS19300 46394d8005da3d75cb3a9c4665a02bdc 138 SUPERFAMILY SSF47413 83 137 2.96E-7 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS19300 46394d8005da3d75cb3a9c4665a02bdc 138 SMART SM00530 83 136 2.1E-7 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS19300 46394d8005da3d75cb3a9c4665a02bdc 138 Gene3D G3DSA:1.10.260.40 82 137 1.0E-9 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02535 284b226642be9589cc326bc25d089e6a 130 TIGRFAM TIGR00156 TIGR00156: TIGR00156 family protein 1 130 3.6E-61 T 10-03-2017 IPR016052 Bacteriophage 933W, L0136 RG49_RS02535 284b226642be9589cc326bc25d089e6a 130 SUPERFAMILY SSF101756 30 130 5.36E-27 T 10-03-2017 IPR005220 Bacterial OB-fold RG49_RS02535 284b226642be9589cc326bc25d089e6a 130 Gene3D G3DSA:2.40.50.200 29 130 3.5E-29 T 10-03-2017 IPR005220 Bacterial OB-fold RG49_RS02535 284b226642be9589cc326bc25d089e6a 130 Pfam PF04076 Bacterial OB fold (BOF) protein 30 130 3.5E-42 T 10-03-2017 IPR005220 Bacterial OB-fold RG49_RS23695 26e88bb20aa45666ba298fd045b8a027 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 100 19.378 T 10-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 RG49_RS23695 26e88bb20aa45666ba298fd045b8a027 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 95 5.0E-21 T 10-03-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 RG49_RS01230 f3a0de9cbf2215b2acf43cbdd96fbcd5 235 Pfam PF09335 SNARE associated Golgi protein 80 197 1.1E-24 T 10-03-2017 IPR032816 SNARE associated Golgi protein RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 PRINTS PR01021 OMPA domain signature 146 161 6.5E-13 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 PRINTS PR01021 OMPA domain signature 116 138 6.5E-13 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 PRINTS PR01021 OMPA domain signature 161 177 6.5E-13 T 10-03-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 132 158 1.4E-7 T 10-03-2017 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 161 178 1.4E-7 T 10-03-2017 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 199 219 1.4E-7 T 10-03-2017 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 179 198 1.4E-7 T 10-03-2017 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 ProSitePatterns PS01068 OmpA-like domain. 148 192 - T 10-03-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 Pfam PF00691 OmpA family 115 210 1.0E-22 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 Pfam PF13488 Glycine zipper 37 85 2.4E-12 T 10-03-2017 RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 SUPERFAMILY SSF103088 103 218 3.92E-38 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS16725 73fda5c9064dcaf9e2ab74e80353758c 219 Gene3D G3DSA:3.30.1330.60 103 216 6.4E-40 T 10-03-2017 IPR006665 OmpA-like domain RG49_RS21215 6ea51bd3c5795f4ea493049cd343d6c3 86 Gene3D G3DSA:3.30.70.20 32 69 9.3E-7 T 10-03-2017 RG49_RS21215 6ea51bd3c5795f4ea493049cd343d6c3 86 SUPERFAMILY SSF54862 31 84 4.45E-9 T 10-03-2017 RG49_RS21215 6ea51bd3c5795f4ea493049cd343d6c3 86 PIRSF PIRSF036548 1 86 5.4E-25 T 10-03-2017 IPR012206 Ferredoxin-like, FixX GO:0005506 RG49_RS06575 081eeebcba10e368db8ba80711c0905e 390 Pfam PF04984 Phage tail sheath protein 91 377 3.8E-56 T 10-03-2017 IPR007067 Tail sheath protein RG49_RS06575 081eeebcba10e368db8ba80711c0905e 390 Pfam PF04984 Phage tail sheath protein 1 93 2.7E-15 T 10-03-2017 IPR007067 Tail sheath protein RG49_RS16055 2f0e6ba9c4d7925b173a354db72b7bc0 103 Pfam PF01527 Transposase 4 77 7.4E-10 T 10-03-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 RG49_RS16055 2f0e6ba9c4d7925b173a354db72b7bc0 103 Gene3D G3DSA:1.10.10.60 10 93 8.3E-20 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS16055 2f0e6ba9c4d7925b173a354db72b7bc0 103 SUPERFAMILY SSF46689 5 96 3.4E-18 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS24300 dba544ddbc138316162a3bb53f91d15e 84 Pfam PF03692 Putative zinc- or iron-chelating domain 2 60 2.6E-6 T 10-03-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein RG49_RS24600 b4b4cd8ffe66dea887912a8ac44d57de 1210 Pfam PF13569 Domain of unknown function (DUF4132) 954 1138 9.7E-43 T 10-03-2017 IPR025406 Domain of unknown function DUF4132 RG49_RS17085 c2a2a507453813d4db15fd2112a4401d 111 Hamap MF_01088 Universal stress protein B [uspB]. 1 107 39.999 T 10-03-2017 IPR019598 Universal stress protein B RG49_RS17085 c2a2a507453813d4db15fd2112a4401d 111 Pfam PF10625 Universal stress protein B (UspB) 1 106 6.3E-55 T 10-03-2017 IPR019598 Universal stress protein B RG49_RS11330 3137a58a24bdcdf04c81fcf0c2041571 461 SUPERFAMILY SSF52540 79 454 3.8E-89 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11330 3137a58a24bdcdf04c81fcf0c2041571 461 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 281 295 - T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS11330 3137a58a24bdcdf04c81fcf0c2041571 461 Gene3D G3DSA:3.40.50.300 192 457 1.3E-94 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS11330 3137a58a24bdcdf04c81fcf0c2041571 461 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 8 68 3.6E-5 T 10-03-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 RG49_RS11330 3137a58a24bdcdf04c81fcf0c2041571 461 Pfam PF00437 Type II/IV secretion system protein 89 353 9.2E-85 T 10-03-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 RG49_RS11330 3137a58a24bdcdf04c81fcf0c2041571 461 Gene3D G3DSA:3.30.450.90 52 186 4.2E-45 T 10-03-2017 RG49_RS16620 4cf32c9bcf38ecc4d39f89a0ab5df7c3 141 SUPERFAMILY SSF53822 2 128 1.85E-29 T 10-03-2017 IPR028082 Periplasmic binding protein-like I RG49_RS16620 4cf32c9bcf38ecc4d39f89a0ab5df7c3 141 Pfam PF13407 Periplasmic binding protein domain 2 97 2.1E-21 T 10-03-2017 IPR025997 Periplasmic binding protein RG49_RS16620 4cf32c9bcf38ecc4d39f89a0ab5df7c3 141 Gene3D G3DSA:3.40.50.2300 2 129 9.6E-33 T 10-03-2017 RG49_RS16585 b21a15f1751161e95d1823853b8ce530 157 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 10-03-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site RG49_RS16585 b21a15f1751161e95d1823853b8ce530 157 Gene3D G3DSA:3.30.70.20 6 67 4.2E-9 T 10-03-2017 RG49_RS16585 b21a15f1751161e95d1823853b8ce530 157 Gene3D G3DSA:3.30.70.20 96 150 3.1E-16 T 10-03-2017 RG49_RS16585 b21a15f1751161e95d1823853b8ce530 157 SUPERFAMILY SSF54862 1 145 2.3E-41 T 10-03-2017 RG49_RS16585 b21a15f1751161e95d1823853b8ce530 157 Gene3D G3DSA:3.30.70.20 68 95 1.9E-13 T 10-03-2017 RG49_RS16585 b21a15f1751161e95d1823853b8ce530 157 Pfam PF13247 4Fe-4S dicluster domain 55 141 6.2E-12 T 10-03-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain RG49_RS14095 879ad00cedf9a671b268009d65d7016e 223 Pfam PF04493 Endonuclease V 12 206 2.8E-73 T 10-03-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 RG49_RS14095 879ad00cedf9a671b268009d65d7016e 223 Hamap MF_00801 Endonuclease V [nfi]. 2 216 35.446 T 10-03-2017 IPR007581 Endonuclease V GO:0004519|GO:0006281 RG49_RS23290 7e0148b9955b55d6cbdc9ebbfda702b9 314 Pfam PF03547 Membrane transport protein 166 307 1.7E-28 T 10-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 RG49_RS23290 7e0148b9955b55d6cbdc9ebbfda702b9 314 Pfam PF03547 Membrane transport protein 6 161 8.1E-35 T 10-03-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 RG49_RS15785 4dd786d3f534a35c3fbd91e656d277f4 110 Pfam PF07119 Protein of unknown function (DUF1375) 15 76 3.7E-12 T 10-03-2017 IPR010780 Protein of unknown function DUF1375 RG49_RS05600 c7698b26c8b6670355ac7da8a946bb9d 276 Pfam PF03239 Iron permease FTR1 family 1 274 2.6E-76 T 10-03-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 RG49_RS05600 c7698b26c8b6670355ac7da8a946bb9d 276 SUPERFAMILY SSF103473 5 263 6.93E-6 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS05600 c7698b26c8b6670355ac7da8a946bb9d 276 TIGRFAM TIGR00145 TIGR00145: FTR1 family protein 1 273 9.1E-106 T 10-03-2017 IPR005217 Iron permease FTR1-like GO:0005381|GO:0005886|GO:0006827|GO:0033573 RG49_RS06150 f54b03733b9accf07b649354c09ff99e 60 Gene3D G3DSA:2.20.25.10 8 59 5.3E-24 T 10-03-2017 RG49_RS06150 f54b03733b9accf07b649354c09ff99e 60 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 25.895 T 10-03-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 RG49_RS06150 f54b03733b9accf07b649354c09ff99e 60 Pfam PF03966 Trm112p-like protein 2 41 1.5E-8 T 10-03-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 RG49_RS06150 f54b03733b9accf07b649354c09ff99e 60 SUPERFAMILY SSF158997 1 55 6.93E-20 T 10-03-2017 RG49_RS18960 135508bea4e52908ac79bdb356013219 267 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 2 267 5.0E-124 T 10-03-2017 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 RG49_RS18960 135508bea4e52908ac79bdb356013219 267 Pfam PF03609 PTS system sorbose-specific iic component 7 238 3.1E-65 T 10-03-2017 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 RG49_RS16715 d7997edec107c0e6dafb6563581aac7f 236 Pfam PF11254 Protein of unknown function (DUF3053) 15 230 3.4E-89 T 10-03-2017 IPR021413 Protein of unknown function DUF3053 RG49_RS09010 fa0d3c949697af67f435b8aef0a96a5a 196 Pfam PF01965 DJ-1/PfpI family 4 170 2.1E-48 T 10-03-2017 IPR002818 DJ-1/PfpI RG49_RS09010 fa0d3c949697af67f435b8aef0a96a5a 196 Gene3D G3DSA:3.40.50.880 2 188 1.6E-58 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS09010 fa0d3c949697af67f435b8aef0a96a5a 196 SUPERFAMILY SSF52317 5 188 2.89E-47 T 10-03-2017 IPR029062 Class I glutamine amidotransferase-like RG49_RS09010 fa0d3c949697af67f435b8aef0a96a5a 196 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 5 183 1.0E-66 T 10-03-2017 IPR006287 Protein deglycase DJ-1 GO:0006517|GO:0030091 RG49_RS20280 a8ef2580fbba5dc084c0e29260d0cdb6 246 Pfam PF04402 Protein of unknown function (DUF541) 30 230 1.2E-44 T 10-03-2017 IPR007497 Protein of unknown function DUF541 RG49_RS16530 55af257b10070992ec20dc468d74428f 107 Pfam PF11742 Protein of unknown function (DUF3302) 3 78 1.9E-42 T 10-03-2017 IPR011223 Uncharacterised conserved protein UCP028770 RG49_RS16530 55af257b10070992ec20dc468d74428f 107 PIRSF PIRSF028770 1 107 1.1E-60 T 10-03-2017 IPR011223 Uncharacterised conserved protein UCP028770 RG49_RS02435 9eedb5517f09f78a67b2daff1c916936 109 Pfam PF06223 Minor tail protein T 6 105 8.1E-40 T 10-03-2017 IPR009350 Minor tail T RG49_RS02435 9eedb5517f09f78a67b2daff1c916936 109 TIGRFAM TIGR01715 phage_lam_T: phage tail assembly protein T 2 106 2.6E-40 T 10-03-2017 IPR009350 Minor tail T RG49_RS00120 46306f556d59932698151c05ab825b24 60 Pfam PF09926 Uncharacterized small protein (DUF2158) 9 47 1.3E-7 T 10-03-2017 IPR019226 Protein of unknown function DUF2158 RG49_RS21690 f88dc9aa701cbe535d01e68eb90355ee 330 SUPERFAMILY SSF53850 24 328 1.19E-96 T 10-03-2017 RG49_RS21690 f88dc9aa701cbe535d01e68eb90355ee 330 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 312 5.5E-56 T 10-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 RG49_RS21690 f88dc9aa701cbe535d01e68eb90355ee 330 Gene3D G3DSA:3.40.190.10 263 329 1.3E-58 T 10-03-2017 RG49_RS21690 f88dc9aa701cbe535d01e68eb90355ee 330 Gene3D G3DSA:3.40.190.10 23 112 1.3E-58 T 10-03-2017 RG49_RS21690 f88dc9aa701cbe535d01e68eb90355ee 330 Gene3D G3DSA:3.40.190.100 113 262 1.2E-57 T 10-03-2017 RG49_RS09265 ccd61426568dc0e6905ca0c162a6c5fe 385 Pfam PF00144 Beta-lactamase 45 357 3.7E-64 T 10-03-2017 IPR001466 Beta-lactamase-related RG49_RS09265 ccd61426568dc0e6905ca0c162a6c5fe 385 Gene3D G3DSA:3.40.710.10 16 371 3.7E-70 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS09265 ccd61426568dc0e6905ca0c162a6c5fe 385 SUPERFAMILY SSF56601 33 361 8.38E-69 T 10-03-2017 IPR012338 Beta-lactamase/transpeptidase-like RG49_RS17060 5a887edb44abee1a78c5115a9fa91f79 680 Gene3D G3DSA:1.10.1370.10 140 349 3.5E-147 T 10-03-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 RG49_RS17060 5a887edb44abee1a78c5115a9fa91f79 680 Gene3D G3DSA:1.10.1370.10 505 678 3.5E-147 T 10-03-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 RG49_RS17060 5a887edb44abee1a78c5115a9fa91f79 680 Gene3D G3DSA:1.20.1050.40 7 138 6.0E-25 T 10-03-2017 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal RG49_RS17060 5a887edb44abee1a78c5115a9fa91f79 680 Gene3D G3DSA:3.40.390.10 360 504 1.6E-61 T 10-03-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 RG49_RS17060 5a887edb44abee1a78c5115a9fa91f79 680 Pfam PF01432 Peptidase family M3 222 677 4.7E-177 T 10-03-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 RG49_RS17060 5a887edb44abee1a78c5115a9fa91f79 680 SUPERFAMILY SSF55486 1 677 1.1E-214 T 10-03-2017 RG49_RS08555 d8b01b9da932c9d18b39be3493bdc33c 364 Hamap MF_01622 tRNA 2-selenouridine synthase [selU]. 3 364 49.516 T 10-03-2017 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 RG49_RS08555 d8b01b9da932c9d18b39be3493bdc33c 364 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 17 349 3.9E-106 T 10-03-2017 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 RG49_RS08555 d8b01b9da932c9d18b39be3493bdc33c 364 SMART SM00450 4 134 4.9E-14 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS08555 d8b01b9da932c9d18b39be3493bdc33c 364 SUPERFAMILY SSF52821 9 66 1.65E-19 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS08555 d8b01b9da932c9d18b39be3493bdc33c 364 SUPERFAMILY SSF52821 94 134 1.65E-19 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS08555 d8b01b9da932c9d18b39be3493bdc33c 364 Gene3D G3DSA:3.40.250.10 11 131 6.3E-32 T 10-03-2017 IPR001763 Rhodanese-like domain RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 SMART SM01274 81 261 5.2E-108 T 10-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 SMART SM00919 271 531 1.0E-130 T 10-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 SUPERFAMILY SSF51735 271 562 3.82E-94 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 Pfam PF03949 Malic enzyme, NAD binding domain 271 530 3.7E-104 T 10-03-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PRINTS PR00072 Malic enzyme signature 267 283 3.1E-74 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PRINTS PR00072 Malic enzyme signature 87 111 3.1E-74 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PRINTS PR00072 Malic enzyme signature 298 314 3.1E-74 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PRINTS PR00072 Malic enzyme signature 183 205 3.1E-74 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PRINTS PR00072 Malic enzyme signature 147 176 3.1E-74 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PRINTS PR00072 Malic enzyme signature 408 424 3.1E-74 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PRINTS PR00072 Malic enzyme signature 242 260 3.1E-74 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 Hamap MF_01619 NAD-dependent malic enzyme [maeA]. 4 565 72.765 T 10-03-2017 IPR023667 NAD-dependent malic enzyme, proteobacteria GO:0004471|GO:0055114 KEGG: 00620+1.1.1.38 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 Gene3D G3DSA:3.40.50.720 269 562 7.1E-109 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 PIRSF PIRSF000106 1 563 5.5E-227 T 10-03-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 Gene3D G3DSA:3.40.50.10380 17 268 1.0E-116 T 10-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 SUPERFAMILY SSF53223 7 270 2.88E-110 T 10-03-2017 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 Pfam PF00390 Malic enzyme, N-terminal domain 81 261 4.6E-80 T 10-03-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 RG49_RS02940 bfad39e0369c239e89296099b49758eb 565 ProSitePatterns PS00331 Malic enzymes signature. 267 283 - T 10-03-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 RG49_RS19845 507d315f9d34cfd230cf84957e6dc385 449 Pfam PF01943 Polysaccharide biosynthesis protein 19 280 2.3E-9 T 10-03-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 RG49_RS17725 530cdc602134d988bdb3b09cabeab7ba 276 SUPERFAMILY SSF51658 1 251 5.5E-51 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS17725 530cdc602134d988bdb3b09cabeab7ba 276 Pfam PF01261 Xylose isomerase-like TIM barrel 19 225 9.0E-34 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS17725 530cdc602134d988bdb3b09cabeab7ba 276 Gene3D G3DSA:3.20.20.150 1 271 6.5E-53 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS21695 34b1ad9278660782fe02aef695c3c6ee 354 Gene3D G3DSA:1.10.3720.10 140 325 3.4E-44 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS21695 34b1ad9278660782fe02aef695c3c6ee 354 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 163 324 3.0E-26 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS21695 34b1ad9278660782fe02aef695c3c6ee 354 SUPERFAMILY SSF161098 142 324 3.92E-44 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13480 5c78f94d8d85740239e195cef56650db 354 PIRSF PIRSF007313 1 354 1.1E-156 T 10-03-2017 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 RG49_RS13480 5c78f94d8d85740239e195cef56650db 354 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 350 1.8E-152 T 10-03-2017 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 RG49_RS02445 5449cab370b012349ff2abc85a369908 109 Pfam PF05939 Phage minor tail protein 2 108 3.3E-37 T 10-03-2017 IPR010265 Bacteriophage lambda, GpM, minor tail RG49_RS20865 0b48a9e1f99ef82a0bed4c2f17b46097 72 Pfam PF06004 Bacterial protein of unknown function (DUF903) 23 71 4.3E-24 T 10-03-2017 IPR010305 Protein of unknown function DUF903 RG49_RS20865 0b48a9e1f99ef82a0bed4c2f17b46097 72 Gene3D G3DSA:2.30.30.100 19 72 6.5E-31 T 10-03-2017 RG49_RS20865 0b48a9e1f99ef82a0bed4c2f17b46097 72 SUPERFAMILY SSF50182 21 71 3.11E-18 T 10-03-2017 IPR010920 LSM domain RG49_RS19565 1e5087778c85c4bd82c5db4cfe1124f6 223 Pfam PF06693 Protein of unknown function (DUF1190) 41 210 4.2E-57 T 10-03-2017 IPR009576 Biofilm formation YgiB RG49_RS19565 1e5087778c85c4bd82c5db4cfe1124f6 223 Hamap MF_01188 UPF0441 protein YgiB [ygiB]. 1 223 36.617 T 10-03-2017 IPR009576 Biofilm formation YgiB RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 186 1.7E-9 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 1.7E-9 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 1.7E-9 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 1.7E-9 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 Gene3D G3DSA:1.10.150.240 17 81 8.0E-36 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 SUPERFAMILY SSF56784 3 194 3.01E-45 T 10-03-2017 IPR023214 HAD-like domain RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 4 184 2.8E-21 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 Gene3D G3DSA:3.40.50.1000 3 16 3.3E-36 T 10-03-2017 IPR023214 HAD-like domain RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 Gene3D G3DSA:3.40.50.1000 83 196 3.3E-36 T 10-03-2017 IPR023214 HAD-like domain RG49_RS14745 618cb3819b24df24fb52fc06c5473f9c 199 Pfam PF13419 Haloacid dehalogenase-like hydrolase 51 184 1.0E-12 T 10-03-2017 IPR023214 HAD-like domain RG49_RS09560 0235befc034c930aa28b7f4ceca7b4c8 165 Pfam PF06496 Protein of unknown function (DUF1097) 9 152 1.6E-27 T 10-03-2017 IPR009476 Protein of unknown function DUF1097 RG49_RS15370 a1d7a82621861acf64f75e6389f719d2 87 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 73 0.005 T 10-03-2017 RG49_RS15370 a1d7a82621861acf64f75e6389f719d2 87 Pfam PF13710 ACT domain 13 73 1.6E-27 T 10-03-2017 RG49_RS15370 a1d7a82621861acf64f75e6389f719d2 87 Gene3D G3DSA:3.30.70.260 1 74 3.3E-14 T 10-03-2017 RG49_RS15370 a1d7a82621861acf64f75e6389f719d2 87 SUPERFAMILY SSF55021 3 75 4.12E-12 T 10-03-2017 RG49_RS20285 bb1cfad3d3e7451672c6ce09a6c4bbde 298 SUPERFAMILY SSF46785 8 87 7.62E-14 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20285 bb1cfad3d3e7451672c6ce09a6c4bbde 298 Gene3D G3DSA:1.10.10.10 7 87 1.0E-18 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS20285 bb1cfad3d3e7451672c6ce09a6c4bbde 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 5.9E-12 T 10-03-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 RG49_RS20285 bb1cfad3d3e7451672c6ce09a6c4bbde 298 Gene3D G3DSA:3.40.190.10 188 261 1.2E-4 T 10-03-2017 RG49_RS20285 bb1cfad3d3e7451672c6ce09a6c4bbde 298 SUPERFAMILY SSF53850 104 283 7.8E-13 T 10-03-2017 RG49_RS20285 bb1cfad3d3e7451672c6ce09a6c4bbde 298 Pfam PF03466 LysR substrate binding domain 89 281 4.4E-11 T 10-03-2017 IPR005119 LysR, substrate-binding RG49_RS06040 6afd28a89336f8a5bdb073bf57c66710 191 Pfam PF03358 NADPH-dependent FMN reductase 1 140 2.9E-34 T 10-03-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 RG49_RS06040 6afd28a89336f8a5bdb073bf57c66710 191 Gene3D G3DSA:3.40.50.360 1 174 1.1E-33 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS06040 6afd28a89336f8a5bdb073bf57c66710 191 SUPERFAMILY SSF52218 1 143 2.33E-30 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS06040 6afd28a89336f8a5bdb073bf57c66710 191 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 2 171 1.3E-73 T 10-03-2017 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 RG49_RS12010 9b90291244a6893c80b1298e3e5413e7 259 SMART SM01133 10 246 6.8E-81 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS12010 9b90291244a6893c80b1298e3e5413e7 259 PIRSF PIRSF001357 5 255 2.6E-78 T 10-03-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 RG49_RS12010 9b90291244a6893c80b1298e3e5413e7 259 Gene3D G3DSA:3.20.20.70 3 254 7.4E-94 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS12010 9b90291244a6893c80b1298e3e5413e7 259 Hamap MF_00592 Deoxyribose-phosphate aldolase [deoC]. 1 259 55.255 T 10-03-2017 IPR023649 Deoxyribose-phosphate aldolase type II GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 RG49_RS12010 9b90291244a6893c80b1298e3e5413e7 259 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 11 232 8.8E-89 T 10-03-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 RG49_RS12010 9b90291244a6893c80b1298e3e5413e7 259 SUPERFAMILY SSF51569 6 246 2.2E-82 T 10-03-2017 RG49_RS12010 9b90291244a6893c80b1298e3e5413e7 259 Pfam PF01791 DeoC/LacD family aldolase 11 245 6.3E-54 T 10-03-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 RG49_RS15640 58d09e253997938c0702784a0490a80f 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 183 3.9E-21 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15640 58d09e253997938c0702784a0490a80f 221 Gene3D G3DSA:3.40.50.1000 88 212 4.3E-32 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15640 58d09e253997938c0702784a0490a80f 221 Gene3D G3DSA:3.40.50.1000 2 19 4.3E-32 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15640 58d09e253997938c0702784a0490a80f 221 Gene3D G3DSA:1.10.150.240 20 77 1.0E-5 T 10-03-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 RG49_RS15640 58d09e253997938c0702784a0490a80f 221 SUPERFAMILY SSF56784 4 211 9.63E-44 T 10-03-2017 IPR023214 HAD-like domain RG49_RS15640 58d09e253997938c0702784a0490a80f 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 1.7E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS15640 58d09e253997938c0702784a0490a80f 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 1.7E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS15640 58d09e253997938c0702784a0490a80f 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 1.7E-5 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS15640 58d09e253997938c0702784a0490a80f 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 67 183 3.6E-12 T 10-03-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 RG49_RS11355 389a5dad656b70da31de26225cbe2bab 65 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 3 59 19.691 T 10-03-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 RG49_RS11355 389a5dad656b70da31de26225cbe2bab 65 Pfam PF03884 Domain of unknown function (DUF329) 7 56 3.6E-25 T 10-03-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 RG49_RS11355 389a5dad656b70da31de26225cbe2bab 65 Gene3D G3DSA:3.30.50.10 1 62 8.2E-28 T 10-03-2017 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 RG49_RS11355 389a5dad656b70da31de26225cbe2bab 65 SUPERFAMILY SSF57716 2 62 2.14E-23 T 10-03-2017 RG49_RS15590 c985a3c3e3ec4449c6414e751233c51d 241 Gene3D G3DSA:1.20.58.220 9 114 2.0E-36 T 10-03-2017 RG49_RS15590 c985a3c3e3ec4449c6414e751233c51d 241 Gene3D G3DSA:1.20.58.220 127 233 1.7E-31 T 10-03-2017 RG49_RS15590 c985a3c3e3ec4449c6414e751233c51d 241 Pfam PF01895 PhoU domain 128 212 1.7E-17 T 10-03-2017 IPR026022 PhoU domain RG49_RS15590 c985a3c3e3ec4449c6414e751233c51d 241 Pfam PF01895 PhoU domain 27 111 6.5E-20 T 10-03-2017 IPR026022 PhoU domain RG49_RS15590 c985a3c3e3ec4449c6414e751233c51d 241 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 13 221 5.1E-71 T 10-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 RG49_RS15590 c985a3c3e3ec4449c6414e751233c51d 241 SUPERFAMILY SSF109755 13 229 1.26E-69 T 10-03-2017 RG49_RS15590 c985a3c3e3ec4449c6414e751233c51d 241 PIRSF PIRSF003107 7 226 5.6E-67 T 10-03-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 RG49_RS00030 d7457c555815d359afee06469c1b8bfa 211 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 1 203 24.344 T 10-03-2017 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 RG49_RS00030 d7457c555815d359afee06469c1b8bfa 211 Pfam PF01794 Ferric reductase like transmembrane component 48 161 2.2E-14 T 10-03-2017 IPR013130 Ferric reductase transmembrane component-like domain RG49_RS19550 265d0972bd15046d7555cfda792abe62 257 Hamap MF_00548 Zinc transporter ZupT [zupT]. 1 252 30.594 T 10-03-2017 IPR023498 Zinc transporter ZupT RG49_RS19550 265d0972bd15046d7555cfda792abe62 257 Pfam PF02535 ZIP Zinc transporter 98 246 2.0E-25 T 10-03-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 RG49_RS19550 265d0972bd15046d7555cfda792abe62 257 Pfam PF02535 ZIP Zinc transporter 6 91 1.1E-7 T 10-03-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 RG49_RS22265 51dcae9eaed28566a0a75c23feb0005e 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 68 105 - T 10-03-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 RG49_RS22265 51dcae9eaed28566a0a75c23feb0005e 178 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 23 164 49.706 T 10-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 RG49_RS22265 51dcae9eaed28566a0a75c23feb0005e 178 Pfam PF14437 MafB19-like deaminase 18 164 2.2E-33 T 10-03-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 RG49_RS22265 51dcae9eaed28566a0a75c23feb0005e 178 Gene3D G3DSA:3.40.140.10 17 162 3.4E-61 T 10-03-2017 RG49_RS22265 51dcae9eaed28566a0a75c23feb0005e 178 SUPERFAMILY SSF53927 15 168 9.2E-60 T 10-03-2017 IPR016193 Cytidine deaminase-like GO:0003824 RG49_RS13035 50ba39a5e7587e96d30d0fca5fd4db4b 65 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 5 60 1.4E-21 T 10-03-2017 IPR019201 Protein of unknown function DUF2065 RG49_RS24660 9349b0c023e13e5b28da19a2c598a33c 90 Pfam PF02583 Metal-sensitive transcriptional repressor 7 86 1.3E-19 T 10-03-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 RG49_RS24975 8276862266830e71f92b1445d788ffbe 406 Pfam PF13439 Glycosyltransferase Family 4 15 210 9.2E-8 T 10-03-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 RG49_RS24975 8276862266830e71f92b1445d788ffbe 406 SUPERFAMILY SSF53756 14 82 3.06E-59 T 10-03-2017 RG49_RS24975 8276862266830e71f92b1445d788ffbe 406 SUPERFAMILY SSF53756 117 404 3.06E-59 T 10-03-2017 RG49_RS24975 8276862266830e71f92b1445d788ffbe 406 TIGRFAM TIGR04005 wcaL: colanic acid biosynthesis glycosyltransferase WcaL 1 406 1.0E-265 T 10-03-2017 IPR023884 Colanic acid biosynthesis, glycosyl transferase, WcaL RG49_RS24975 8276862266830e71f92b1445d788ffbe 406 Pfam PF00534 Glycosyl transferases group 1 217 383 1.1E-39 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS24975 8276862266830e71f92b1445d788ffbe 406 Gene3D G3DSA:3.40.50.2000 201 384 1.5E-24 T 10-03-2017 RG49_RS08305 06b26eaeff3381c46dc9050c52ac4cda 110 Pfam PF11604 Copper binding periplasmic protein CusF 42 103 1.4E-21 T 10-03-2017 IPR021647 Copper binding periplasmic protein CusF RG49_RS24105 6adef57f29618c27bdcb14c1b0c08dfe 87 Pfam PF03927 NapD protein 5 81 8.9E-27 T 10-03-2017 IPR005623 Chaperone NapD, nitrate reductase assembly RG49_RS19160 d2c3a295c16faf3cb069b40d540c0c00 436 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 9 433 35.158 T 10-03-2017 IPR021144 Uncharacterised protein family UPF0597 RG49_RS19160 d2c3a295c16faf3cb069b40d540c0c00 436 Pfam PF03313 Serine dehydratase alpha chain 178 428 2.6E-48 T 10-03-2017 IPR005130 Serine dehydratase-like, alpha subunit RG49_RS19160 d2c3a295c16faf3cb069b40d540c0c00 436 PIRSF PIRSF006054 5 435 2.7E-185 T 10-03-2017 IPR021144 Uncharacterised protein family UPF0597 RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 SUPERFAMILY SSF56801 24 535 6.93E-143 T 10-03-2017 RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 Gene3D G3DSA:2.30.38.10 359 433 3.7E-24 T 10-03-2017 RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 525 7.1E-19 T 10-03-2017 IPR025110 AMP-binding enzyme C-terminal domain RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 10-03-2017 IPR020845 AMP-binding, conserved site RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 Gene3D G3DSA:3.40.50.980 199 349 5.5E-38 T 10-03-2017 RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 Pfam PF00501 AMP-binding enzyme 31 439 3.2E-100 T 10-03-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 Gene3D G3DSA:3.40.50.980 25 198 2.1E-33 T 10-03-2017 RG49_RS01515 13487536a7743cbbeaf16d93bed49bd4 548 Gene3D G3DSA:3.30.300.30 434 533 2.8E-30 T 10-03-2017 RG49_RS18915 e61d6c47f0c413069058deb6dcf035d8 131 Gene3D G3DSA:3.40.1350.10 24 128 3.9E-37 T 10-03-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 RG49_RS18915 e61d6c47f0c413069058deb6dcf035d8 131 SUPERFAMILY SSF52980 17 125 4.4E-23 T 10-03-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 RG49_RS18915 e61d6c47f0c413069058deb6dcf035d8 131 Pfam PF02021 Uncharacterised protein family UPF0102 24 114 8.7E-24 T 10-03-2017 IPR003509 Uncharacterised protein family UPF0102 RG49_RS18915 e61d6c47f0c413069058deb6dcf035d8 131 Hamap MF_00048 UPF0102 protein YraN [yraN]. 16 128 23.684 T 10-03-2017 IPR003509 Uncharacterised protein family UPF0102 RG49_RS18915 e61d6c47f0c413069058deb6dcf035d8 131 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 10 131 3.3E-61 T 10-03-2017 IPR003509 Uncharacterised protein family UPF0102 RG49_RS23150 41032b04170ea48fed1e6276d5892a37 130 Pfam PF07037 Putative transcription regulator (DUF1323) 8 129 1.5E-56 T 10-03-2017 IPR010749 Protein of unknown function DUF1323 RG49_RS23150 41032b04170ea48fed1e6276d5892a37 130 Gene3D G3DSA:1.10.10.10 7 48 9.7E-8 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS23150 41032b04170ea48fed1e6276d5892a37 130 ProDom PD060594 TRANSCRIPTION YFED YFEC DNA-BINDING REGULATION NEGATIVE REGULATOR STY2653 ECS3274 STY2652 8 129 4.0E-68 T 10-03-2017 IPR010749 Protein of unknown function DUF1323 RG49_RS23150 41032b04170ea48fed1e6276d5892a37 130 SUPERFAMILY SSF46955 5 82 7.23E-13 T 10-03-2017 IPR009061 Putative DNA-binding domain RG49_RS14010 e82b1aa1f92f0bd46703b0ee99655019 147 Gene3D G3DSA:3.40.630.30 1 141 1.4E-27 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS14010 e82b1aa1f92f0bd46703b0ee99655019 147 SUPERFAMILY SSF55729 3 139 2.36E-26 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS14010 e82b1aa1f92f0bd46703b0ee99655019 147 Pfam PF13673 Acetyltransferase (GNAT) domain 43 131 9.1E-16 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS17530 b994f7e159789c2d72f9d9ecfbe6ddb1 75 SMART SM00899 1 72 4.2E-8 T 10-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 RG49_RS17530 b994f7e159789c2d72f9d9ecfbe6ddb1 75 Pfam PF04023 FeoA domain 5 71 3.0E-8 T 10-03-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 RG49_RS17530 b994f7e159789c2d72f9d9ecfbe6ddb1 75 SUPERFAMILY SSF50037 2 73 7.33E-17 T 10-03-2017 IPR008988 Transcriptional repressor, C-terminal RG49_RS11975 247a282ce885f477136173a67e5d6f2a 322 Gene3D G3DSA:3.40.50.1000 176 302 5.2E-40 T 10-03-2017 IPR023214 HAD-like domain RG49_RS11975 247a282ce885f477136173a67e5d6f2a 322 SUPERFAMILY SSF56784 109 316 1.06E-47 T 10-03-2017 IPR023214 HAD-like domain RG49_RS11975 247a282ce885f477136173a67e5d6f2a 322 Gene3D G3DSA:1.10.150.210 126 175 1.3E-27 T 10-03-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 RG49_RS11975 247a282ce885f477136173a67e5d6f2a 322 Pfam PF12710 haloacid dehalogenase-like hydrolase 142 280 1.7E-18 T 10-03-2017 RG49_RS11975 247a282ce885f477136173a67e5d6f2a 322 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 97 315 2.2E-94 T 10-03-2017 RG49_RS11975 247a282ce885f477136173a67e5d6f2a 322 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 112 283 4.5E-26 T 10-03-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 RG49_RS09120 111a14e2f39729750ab3bfc622cd4712 457 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 10-03-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 RG49_RS09120 111a14e2f39729750ab3bfc622cd4712 457 PIRSF PIRSF006060 1 456 2.2E-77 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS09120 111a14e2f39729750ab3bfc622cd4712 457 Pfam PF00324 Amino acid permease 15 451 4.1E-105 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS02550 a937dafde573e8b25ba4b0c132b52e99 395 Pfam PF07690 Major Facilitator Superfamily 13 341 9.8E-29 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS02550 a937dafde573e8b25ba4b0c132b52e99 395 Gene3D G3DSA:1.20.1250.20 8 185 1.5E-23 T 10-03-2017 RG49_RS02550 a937dafde573e8b25ba4b0c132b52e99 395 Gene3D G3DSA:1.20.1250.20 205 382 1.5E-9 T 10-03-2017 RG49_RS02550 a937dafde573e8b25ba4b0c132b52e99 395 SUPERFAMILY SSF103473 7 384 1.28E-44 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23210 e8466c8885c90b263f456479c62c7777 415 Pfam PF02378 Phosphotransferase system, EIIC 41 338 1.6E-12 T 10-03-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 RG49_RS19190 5ff29563b74530a50780d9f4bebaa4b5 121 Pfam PF05656 Protein of unknown function (DUF805) 11 117 4.0E-35 T 10-03-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 RG49_RS12940 0373f0dcb85ad5deb6a8d78e37a5b8da 101 SUPERFAMILY SSF52794 3 95 7.59E-18 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS12940 0373f0dcb85ad5deb6a8d78e37a5b8da 101 Gene3D G3DSA:3.40.50.270 4 93 1.4E-17 T 10-03-2017 RG49_RS12940 0373f0dcb85ad5deb6a8d78e37a5b8da 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 79 1.1E-13 T 10-03-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 RG49_RS23545 f4eb4d7cb66164480bde4b4c647dc70e 238 SUPERFAMILY SSF161098 17 223 6.28E-37 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23545 f4eb4d7cb66164480bde4b4c647dc70e 238 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 122 2.4E-13 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS23545 f4eb4d7cb66164480bde4b4c647dc70e 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 224 2.2E-15 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS23545 f4eb4d7cb66164480bde4b4c647dc70e 238 Gene3D G3DSA:1.10.3720.10 20 228 5.1E-38 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS13110 cb5ed36eea9850de2081ab737b329046 350 Gene3D G3DSA:3.40.50.300 115 275 2.6E-49 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13110 cb5ed36eea9850de2081ab737b329046 350 SUPERFAMILY SSF52540 114 340 8.75E-59 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS13110 cb5ed36eea9850de2081ab737b329046 350 Gene3D G3DSA:1.10.40.50 276 345 5.5E-26 T 10-03-2017 RG49_RS13110 cb5ed36eea9850de2081ab737b329046 350 Pfam PF03193 Protein of unknown function, DUF258 100 276 5.3E-57 T 10-03-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 RG49_RS13110 cb5ed36eea9850de2081ab737b329046 350 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 73 334 3.1E-101 T 10-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 RG49_RS13110 cb5ed36eea9850de2081ab737b329046 350 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 40 340 37.976 T 10-03-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 2 15 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 117 140 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 55 71 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 213 235 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 20 37 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 279 294 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 261 279 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 358 374 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 236 258 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 PRINTS PR01007 Flagellar hook-length control protein signature 294 317 1.2E-116 T 10-03-2017 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 RG49_RS00195 f8954534a7dba1ceca90cc3855e14265 375 Pfam PF02120 Flagellar hook-length control protein FliK 250 328 8.4E-20 T 10-03-2017 IPR021136 Flagellar hook-length control protein-like, C-terminal RG49_RS21325 e2b987a10d0bacc61f47994a9bbc71b2 107 ProDom PD070788 MEMBRANE OXIDASE SUBUNIT CYTOCHROME YGBE INNER STY3057 TRANSMEMBRANE 6 107 3.0E-52 T 10-03-2017 IPR022721 Protein of unknown function DUF3561 RG49_RS21325 e2b987a10d0bacc61f47994a9bbc71b2 107 Pfam PF12084 Protein of unknown function (DUF3561) 1 107 6.0E-48 T 10-03-2017 IPR022721 Protein of unknown function DUF3561 RG49_RS22105 1f0a0316d76e1fddc9f4bcead74a2a0d 107 Pfam PF10043 Predicted periplasmic lipoprotein (DUF2279) 24 99 8.2E-10 T 10-03-2017 IPR018736 Protein of unknown function DUF2279, periplasmic lipoprotein RG49_RS22105 1f0a0316d76e1fddc9f4bcead74a2a0d 107 PIRSF PIRSF034456 1 106 7.2E-59 T 10-03-2017 IPR017028 Uncharacterised conserved protein UCP034456 RG49_RS12115 66319064d61836b210e41c9ee90775ca 241 SUPERFAMILY SSF46894 145 209 4.08E-12 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS12115 66319064d61836b210e41c9ee90775ca 241 Gene3D G3DSA:1.10.10.10 137 209 1.6E-11 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS12115 66319064d61836b210e41c9ee90775ca 241 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 9.3E-10 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS12115 66319064d61836b210e41c9ee90775ca 241 SMART SM00421 151 208 3.9E-11 T 10-03-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 RG49_RS09295 1d368401c814de78cffea8e0e4c418fa 275 Gene3D G3DSA:1.10.3720.10 71 269 1.1E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS09295 1d368401c814de78cffea8e0e4c418fa 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 269 6.4E-23 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS09295 1d368401c814de78cffea8e0e4c418fa 275 SUPERFAMILY SSF161098 75 258 1.7E-36 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS17065 dc8cf8cc515f3370699496d6efc7f464 250 SUPERFAMILY SSF53335 13 246 3.81E-74 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17065 dc8cf8cc515f3370699496d6efc7f464 250 Gene3D G3DSA:3.40.50.150 57 247 3.9E-73 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS17065 dc8cf8cc515f3370699496d6efc7f464 250 Gene3D G3DSA:3.40.1630.10 1 56 4.3E-30 T 10-03-2017 RG49_RS17065 dc8cf8cc515f3370699496d6efc7f464 250 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 3 248 37.951 T 10-03-2017 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 RG49_RS17065 dc8cf8cc515f3370699496d6efc7f464 250 Pfam PF04445 Putative SAM-dependent methyltransferase 19 246 3.2E-105 T 10-03-2017 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 RG49_RS14525 d7a4af65a4005bf707f1f527bdcd3a5e 199 Pfam PF07305 Protein of unknown function (DUF1454) 9 192 2.9E-86 T 10-03-2017 IPR009918 Protein of unknown function DUF1454 RG49_RS04300 5e876b2c040d02e51b8211de91219860 168 SUPERFAMILY SSF47240 5 155 1.98E-44 T 10-03-2017 IPR009078 Ferritin-like superfamily RG49_RS04300 5e876b2c040d02e51b8211de91219860 168 Gene3D G3DSA:1.20.1260.10 5 160 1.9E-52 T 10-03-2017 IPR012347 Ferritin-related RG49_RS04300 5e876b2c040d02e51b8211de91219860 168 Pfam PF05974 Domain of unknown function (DUF892) 5 155 2.9E-48 T 10-03-2017 IPR010287 Domain of unknown function DUF892 RG49_RS22490 55395f810860604ad5410bd5db32f42d 337 SMART SM00530 18 79 2.2E-6 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS22490 55395f810860604ad5410bd5db32f42d 337 Hamap MF_02017 Cytoskeleton protein RodZ [rodZ]. 1 332 45.737 T 10-03-2017 IPR023690 Cytoskeleton protein RodZ GO:0008360|GO:0016021 RG49_RS22490 55395f810860604ad5410bd5db32f42d 337 Gene3D G3DSA:1.10.260.40 6 86 1.0E-14 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS22490 55395f810860604ad5410bd5db32f42d 337 Pfam PF13464 Domain of unknown function (DUF4115) 255 329 9.3E-24 T 10-03-2017 IPR025194 Domain of unknown function DUF4115 RG49_RS22490 55395f810860604ad5410bd5db32f42d 337 Pfam PF13413 Helix-turn-helix domain 18 78 5.1E-15 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS22490 55395f810860604ad5410bd5db32f42d 337 SUPERFAMILY SSF47413 14 83 9.65E-9 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS16570 da354cf16538711e0089dc72b6ab149d 155 Pfam PF04074 Domain of unknown function (DUF386) 1 149 2.0E-41 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS16570 da354cf16538711e0089dc72b6ab149d 155 SUPERFAMILY SSF51197 1 152 1.9E-42 T 10-03-2017 RG49_RS16570 da354cf16538711e0089dc72b6ab149d 155 Gene3D G3DSA:2.60.120.370 1 151 5.7E-49 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS16570 da354cf16538711e0089dc72b6ab149d 155 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 153 7.0E-67 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS02340 655b7ce9deb6f986d355ed37ada816c7 177 SUPERFAMILY SSF53955 5 172 1.23E-34 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS02340 655b7ce9deb6f986d355ed37ada816c7 177 Pfam PF00959 Phage lysozyme 48 166 2.1E-30 T 10-03-2017 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 RG49_RS02340 655b7ce9deb6f986d355ed37ada816c7 177 Gene3D G3DSA:1.10.530.40 29 174 1.7E-29 T 10-03-2017 IPR023347 Lysozyme domain GO:0003796 RG49_RS06540 902029146ee7a45a99eb941a2395f71d 72 Pfam PF04606 Ogr/Delta-like zinc finger 4 49 1.1E-20 T 10-03-2017 IPR007684 Zinc finger, Ogr/Delta-type RG49_RS06780 64e55c42078d0d56bb520381025f1f4c 402 Pfam PF07690 Major Facilitator Superfamily 223 388 3.0E-17 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS06780 64e55c42078d0d56bb520381025f1f4c 402 Gene3D G3DSA:1.20.1250.20 215 396 2.3E-24 T 10-03-2017 RG49_RS06780 64e55c42078d0d56bb520381025f1f4c 402 SUPERFAMILY SSF103473 11 390 4.97E-45 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS06780 64e55c42078d0d56bb520381025f1f4c 402 Gene3D G3DSA:1.20.1250.20 11 186 6.9E-12 T 10-03-2017 RG49_RS14405 ee33b1f96fbb9fc32c120416e947a427 301 Pfam PF00892 EamA-like transporter family 152 289 6.6E-26 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS14405 ee33b1f96fbb9fc32c120416e947a427 301 Pfam PF00892 EamA-like transporter family 13 141 1.1E-22 T 10-03-2017 IPR000620 EamA domain GO:0016020|GO:0016021 RG49_RS14405 ee33b1f96fbb9fc32c120416e947a427 301 SUPERFAMILY SSF103481 189 292 1.7E-16 T 10-03-2017 RG49_RS14405 ee33b1f96fbb9fc32c120416e947a427 301 SUPERFAMILY SSF103481 44 144 3.53E-14 T 10-03-2017 RG49_RS13270 7f1b90f0b7284853cc73fd05d36b37b4 512 SMART SM00862 24 100 2.7E-18 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS13270 7f1b90f0b7284853cc73fd05d36b37b4 512 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 100 4.6E-19 T 10-03-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 RG49_RS13270 7f1b90f0b7284853cc73fd05d36b37b4 512 SUPERFAMILY SSF46894 2 102 3.4E-20 T 10-03-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 RG49_RS13270 7f1b90f0b7284853cc73fd05d36b37b4 512 Gene3D G3DSA:1.10.10.10 2 103 1.8E-23 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13270 7f1b90f0b7284853cc73fd05d36b37b4 512 Gene3D G3DSA:1.25.40.10 356 375 5.5E-4 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS13270 7f1b90f0b7284853cc73fd05d36b37b4 512 Gene3D G3DSA:1.25.40.10 420 486 5.5E-4 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS19220 06d0c04686cf093876a7be5f2128f8f0 122 Pfam PF06476 Protein of unknown function (DUF1090) 11 116 1.4E-36 T 10-03-2017 IPR009468 Protein of unknown function DUF1090 RG49_RS12865 c6a7016e72949239cb6ed54e68b1c640 280 Pfam PF01261 Xylose isomerase-like TIM barrel 29 233 1.2E-25 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12865 c6a7016e72949239cb6ed54e68b1c640 280 Gene3D G3DSA:3.20.20.150 11 277 5.6E-51 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS12865 c6a7016e72949239cb6ed54e68b1c640 280 SUPERFAMILY SSF51658 1 258 8.38E-51 T 10-03-2017 IPR013022 Xylose isomerase-like, TIM barrel domain RG49_RS10090 6cd37fa58b17e883d94028ce6d9f889f 273 Pfam PF06067 Domain of unknown function (DUF932) 37 262 2.2E-55 T 10-03-2017 IPR026325 Protein of unknown function DUF932 RG49_RS02210 75f83192dfeb29ae8a707782b7576223 62 Pfam PF05358 DicB protein 1 62 1.6E-48 T 10-03-2017 IPR008022 DicB RG49_RS02210 75f83192dfeb29ae8a707782b7576223 62 ProDom PD053043 DIVISION CELL INHIBITION INHIBITOR ENCODED DICB PROPHAGE BY WITHIN CP- 1 62 6.0E-30 T 10-03-2017 IPR008022 DicB RG49_RS15890 1c33a7a64691bb4ff675788cf927599d 32 Pfam PF08049 IlvB leader peptide 1 32 4.7E-18 T 10-03-2017 IPR012566 IlvB leader peptide RG49_RS02680 18d1c634bc57f7386f29c1a0c602bee7 88 Pfam PF01381 Helix-turn-helix 18 69 1.2E-14 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS02680 18d1c634bc57f7386f29c1a0c602bee7 88 Gene3D G3DSA:1.10.260.40 10 75 3.2E-15 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02680 18d1c634bc57f7386f29c1a0c602bee7 88 SUPERFAMILY SSF47413 5 70 3.22E-17 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS02680 18d1c634bc57f7386f29c1a0c602bee7 88 SMART SM00530 16 71 2.1E-10 T 10-03-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 RG49_RS04250 8c594a998eee7b31f51598408074e2db 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 204 6.8E-80 T 10-03-2017 IPR006070 YrdC-like domain GO:0003725 RG49_RS04250 8c594a998eee7b31f51598408074e2db 206 Pfam PF01300 Telomere recombination 23 198 2.8E-46 T 10-03-2017 IPR006070 YrdC-like domain GO:0003725 RG49_RS04250 8c594a998eee7b31f51598408074e2db 206 Gene3D G3DSA:3.90.870.10 2 203 3.2E-65 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS04250 8c594a998eee7b31f51598408074e2db 206 SUPERFAMILY SSF55821 1 204 2.66E-66 T 10-03-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain RG49_RS03575 35295f629e2c47060978af587d4ae52d 468 Pfam PF13264 Domain of unknown function (DUF4055) 249 386 1.0E-45 T 10-03-2017 IPR025129 Domain of unknown function DUF4055 RG49_RS16400 efdf560360bc0c65dad4842fa1d764ef 227 Gene3D G3DSA:2.60.40.1620 116 203 1.0E-4 T 10-03-2017 IPR021658 Domain of unknown function DUF3251 RG49_RS16400 efdf560360bc0c65dad4842fa1d764ef 227 Pfam PF11622 Protein of unknown function (DUF3251) 54 204 5.7E-6 T 10-03-2017 IPR021658 Domain of unknown function DUF3251 RG49_RS19820 1bec76be687a06418a3a114017a4ad6f 619 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 250 615 1.1E-66 T 10-03-2017 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain RG49_RS19820 1bec76be687a06418a3a114017a4ad6f 619 SUPERFAMILY SSF52440 380 510 2.65E-39 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS19820 1bec76be687a06418a3a114017a4ad6f 619 SUPERFAMILY SSF56059 497 614 3.04E-77 T 10-03-2017 RG49_RS19820 1bec76be687a06418a3a114017a4ad6f 619 SUPERFAMILY SSF56059 205 379 3.04E-77 T 10-03-2017 RG49_RS19820 1bec76be687a06418a3a114017a4ad6f 619 Pfam PF05257 CHAP domain 52 149 1.2E-11 T 10-03-2017 IPR007921 CHAP domain RG49_RS19820 1bec76be687a06418a3a114017a4ad6f 619 SUPERFAMILY SSF54001 10 197 2.65E-61 T 10-03-2017 RG49_RS10590 b1bb87a88d46d206377d012c12293022 378 Pfam PF01609 Transposase DDE domain 102 343 2.7E-28 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS10590 b1bb87a88d46d206377d012c12293022 378 Pfam PF13808 DDE_Tnp_1-associated 7 94 9.5E-33 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS02160 0cf2ea0c11bdcb07e43c5ce7edef3229 113 ProDom PD073251 YNFB PERIPLASMIC SECRETED ORF9 PRECURSOR SIGNAL SIMILAR ECS2289 EXPORTED ESCHERICHIA 1 113 1.0E-53 T 10-03-2017 IPR009700 Protein of unknown function DUF1283 RG49_RS02160 0cf2ea0c11bdcb07e43c5ce7edef3229 113 Hamap MF_01581 UPF0482 protein YnfB [ynfB]. 2 113 28.89 T 10-03-2017 IPR009700 Protein of unknown function DUF1283 RG49_RS02160 0cf2ea0c11bdcb07e43c5ce7edef3229 113 Pfam PF06932 Protein of unknown function (DUF1283) 32 113 1.5E-41 T 10-03-2017 IPR009700 Protein of unknown function DUF1283 RG49_RS17095 14cfe6a3d3e68d767bd41c320f32a9b9 499 Pfam PF01384 Phosphate transporter family 30 488 1.4E-85 T 10-03-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 RG49_RS13865 c93c8f314eb2a28915971d9ae89a9ac9 446 SUPERFAMILY SSF56935 26 446 1.53E-154 T 10-03-2017 RG49_RS13865 c93c8f314eb2a28915971d9ae89a9ac9 446 Pfam PF02264 LamB porin 28 446 3.5E-145 T 10-03-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 RG49_RS13865 c93c8f314eb2a28915971d9ae89a9ac9 446 Gene3D G3DSA:2.40.170.10 26 446 1.5E-176 T 10-03-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 RG49_RS13865 c93c8f314eb2a28915971d9ae89a9ac9 446 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 32 442 0.0 T 10-03-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 RG49_RS13865 c93c8f314eb2a28915971d9ae89a9ac9 446 Hamap MF_01301 Maltoporin [lamB]. 4 446 44.865 T 10-03-2017 IPR023738 Maltoporin GO:0009279|GO:0015481|GO:0015768|GO:0042956|GO:0042958 RG49_RS22400 7488463354ecbdbf4d07993f0b67ae82 284 Gene3D G3DSA:3.40.50.1820 39 276 6.0E-50 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS22400 7488463354ecbdbf4d07993f0b67ae82 284 SUPERFAMILY SSF53474 23 280 1.58E-45 T 10-03-2017 IPR029058 Alpha/Beta hydrolase fold RG49_RS22400 7488463354ecbdbf4d07993f0b67ae82 284 Pfam PF12146 Serine aminopeptidase, S33 77 187 6.8E-13 T 10-03-2017 IPR022742 Serine aminopeptidase, S33 RG49_RS12220 8369021a6c61e7284b151922991920ea 458 TIGRFAM TIGR02332 HpaX: 4-hydroxyphenylacetate permease 28 439 8.5E-270 T 10-03-2017 IPR012707 4-hydroxyphenylacetate permease GO:1900754|GO:1901241 RG49_RS12220 8369021a6c61e7284b151922991920ea 458 Gene3D G3DSA:1.20.1250.20 263 447 8.3E-20 T 10-03-2017 RG49_RS12220 8369021a6c61e7284b151922991920ea 458 Pfam PF07690 Major Facilitator Superfamily 40 413 2.0E-48 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS12220 8369021a6c61e7284b151922991920ea 458 SUPERFAMILY SSF103473 25 448 1.7E-79 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS12220 8369021a6c61e7284b151922991920ea 458 Gene3D G3DSA:1.20.1250.20 32 232 9.5E-42 T 10-03-2017 RG49_RS06590 d9800e09a9a55cd599b0d91f9cc8a0e0 147 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 10 142 1.5E-26 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS04985 e02c82f749b1fa75aa870bff57531423 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 282 1.5E-17 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04985 e02c82f749b1fa75aa870bff57531423 285 SUPERFAMILY SSF161098 6 274 4.32E-53 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS04985 e02c82f749b1fa75aa870bff57531423 285 Gene3D G3DSA:1.10.3720.10 3 273 1.3E-46 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS22060 0964b88bae051b5140427145ee7ba2a6 243 Gene3D G3DSA:3.60.140.10 3 242 6.4E-99 T 10-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase RG49_RS22060 0964b88bae051b5140427145ee7ba2a6 243 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 241 1.0E-78 T 10-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase RG49_RS22060 0964b88bae051b5140427145ee7ba2a6 243 SUPERFAMILY SSF64438 4 242 9.52E-91 T 10-03-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic RG49_RS22060 0964b88bae051b5140427145ee7ba2a6 243 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 25 242 3.5E-83 T 10-03-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase RG49_RS09250 5f90a9f26aecc2b94d1dc59611816b6f 364 ProDom PD041438 LIPOPROTEIN YAIW PRECURSOR SIGNAL MEMBRANE OUTER LIPOPROTEIN ECS0428 XAC0592 SECRETED 20 364 0.0 T 10-03-2017 IPR011673 Protein of unknown function DUF1615 RG49_RS09250 5f90a9f26aecc2b94d1dc59611816b6f 364 Pfam PF07759 Protein of unknown function (DUF1615) 50 363 2.1E-148 T 10-03-2017 IPR011673 Protein of unknown function DUF1615 RG49_RS11760 a33a75c5a1f02cad50db0ba151a25056 373 SUPERFAMILY SSF141571 190 277 2.75E-10 T 10-03-2017 RG49_RS21900 45587a4a3216e52ee0b0313c27dc30ef 244 ProDom PD037484 CAPSID DETERMINATION SIZE HEAD GLYCOPROTEIN SID MORPHOGENESIS CP-933I ENCODED LATE 1 244 2.0E-140 T 10-03-2017 RG49_RS10690 8227e23e5c598ff7ef23e96a012882b2 470 TIGRFAM TIGR03362 VI_chp_7: type VI secretion-associated protein, VC_A0119 family 11 466 1.5E-155 T 10-03-2017 IPR017739 Type VI secretion system-associated, VCA0119 RG49_RS10690 8227e23e5c598ff7ef23e96a012882b2 470 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ 223 465 7.6E-71 T 10-03-2017 IPR017739 Type VI secretion system-associated, VCA0119 RG49_RS10125 77364a7bf7ef8903ea3078c952814e3b 158 Gene3D G3DSA:3.40.140.10 36 158 3.4E-50 T 10-03-2017 RG49_RS10125 77364a7bf7ef8903ea3078c952814e3b 158 Pfam PF04002 RadC-like JAB domain 38 157 2.3E-44 T 10-03-2017 IPR025657 RadC-like JAB domain RG49_RS10125 77364a7bf7ef8903ea3078c952814e3b 158 TIGRFAM TIGR00608 radc: DNA repair protein RadC 36 158 5.0E-45 T 10-03-2017 IPR001405 RadC protein RG49_RS00275 ca8bbf5c2a176e663c239a818271d205 470 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 106 2.5E-21 T 10-03-2017 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 RG49_RS00275 ca8bbf5c2a176e663c239a818271d205 470 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 226 455 4.0E-59 T 10-03-2017 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 RG49_RS10960 2a381e1e09c703d61823ce7f7d5643e3 241 Pfam PF00696 Amino acid kinase family 10 219 3.9E-28 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS10960 2a381e1e09c703d61823ce7f7d5643e3 241 PIRSF PIRSF005650 4 241 2.2E-89 T 10-03-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 RG49_RS10960 2a381e1e09c703d61823ce7f7d5643e3 241 SUPERFAMILY SSF53633 7 240 3.93E-72 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS10960 2a381e1e09c703d61823ce7f7d5643e3 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.437 T 10-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 RG49_RS10960 2a381e1e09c703d61823ce7f7d5643e3 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 7.3E-104 T 10-03-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 RG49_RS10960 2a381e1e09c703d61823ce7f7d5643e3 241 Gene3D G3DSA:3.40.1160.10 3 240 1.4E-85 T 10-03-2017 IPR001048 Aspartate/glutamate/uridylate kinase RG49_RS12635 7968e50ce009e052eb38faa515724a49 150 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 150 3.0E-63 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS12635 7968e50ce009e052eb38faa515724a49 150 SUPERFAMILY SSF51197 1 149 1.68E-43 T 10-03-2017 RG49_RS12635 7968e50ce009e052eb38faa515724a49 150 Gene3D G3DSA:2.60.120.370 1 149 2.2E-50 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS12635 7968e50ce009e052eb38faa515724a49 150 Pfam PF04074 Domain of unknown function (DUF386) 1 147 3.1E-45 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS00405 96c5f61e193689d16bb38315cf420562 83 ProDom PD060536 YECJ YPO1738 1 77 1.0E-37 T 10-03-2017 IPR020262 Uncharacterised protein family YecJ RG49_RS00405 96c5f61e193689d16bb38315cf420562 83 Pfam PF10964 Protein of unknown function (DUF2766) 1 78 2.3E-48 T 10-03-2017 IPR020262 Uncharacterised protein family YecJ RG49_RS15655 2c6f14ef258fb7a6625ed136577f14de 253 Gene3D G3DSA:3.90.470.20 36 111 7.2E-8 T 10-03-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.8E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.8E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.8E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 6.8E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.8E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.8E-39 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 243 1.3E-59 T 10-03-2017 RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 8.1E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.1E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.1E-13 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 Gene3D G3DSA:3.40.50.720 3 245 1.2E-76 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS24495 878ffbf3dc881e79447426c3328a84cd 253 SUPERFAMILY SSF51735 3 245 3.64E-75 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS06745 6b7d93c41ffdf184edad302901d06861 66 Pfam PF10893 Protein of unknown function (DUF2724) 1 62 2.7E-31 T 10-03-2017 IPR021221 Bacteriophage 186, Fil RG49_RS03855 2e64ad7fa19a7a95b6a610cdebf618a8 508 TIGRFAM TIGR00819 ydaH: AbgT transporter family 1 507 1.5E-280 T 10-03-2017 IPR011540 AbgT, Proteobacteria GO:0015558|GO:1902604 RG49_RS03855 2e64ad7fa19a7a95b6a610cdebf618a8 508 Pfam PF03806 AbgT putative transporter family 14 505 1.5E-207 T 10-03-2017 IPR004697 p-aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 RG49_RS06605 9e3971e0ef2e4eae097889eac4a5d54e 201 TIGRFAM TIGR01634 tail_P2_I: phage tail protein I 5 140 8.3E-58 T 10-03-2017 IPR006521 Tail protein I RG49_RS06605 9e3971e0ef2e4eae097889eac4a5d54e 201 Pfam PF09684 Phage tail protein (Tail_P2_I) 5 140 5.8E-54 T 10-03-2017 IPR006521 Tail protein I RG49_RS12140 79e0914b36732da3b6d7943fca0a33c0 165 Pfam PF10696 Protein of unknown function (DUF2501) 85 163 4.1E-27 T 10-03-2017 IPR019637 Protein of unknown function DUF2501 RG49_RS04530 2d9b33c1d9cbd55c714118a3e57d55ce 238 SUPERFAMILY SSF110857 54 168 2.75E-10 T 10-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like RG49_RS04530 2d9b33c1d9cbd55c714118a3e57d55ce 238 Pfam PF04752 ChaC-like protein 54 222 6.7E-56 T 10-03-2017 IPR006840 ChaC-like protein Reactome: R-HSA-174403 RG49_RS04530 2d9b33c1d9cbd55c714118a3e57d55ce 238 Gene3D G3DSA:3.10.490.10 48 216 8.6E-47 T 10-03-2017 IPR013024 Butirosin biosynthesis, BtrG-like RG49_RS07095 bfce72acec61e4dc9d964e50cd6c0f35 237 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 223 3.6E-14 T 10-03-2017 RG49_RS19320 a2eb5d385ad3a165afe233ad8a00166e 477 Pfam PF13520 Amino acid permease 11 439 3.3E-30 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS19320 a2eb5d385ad3a165afe233ad8a00166e 477 PIRSF PIRSF006060 1 476 1.4E-53 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS13930 ea8c0d748b8851e307dded14ffe3c860 80 Pfam PF11106 Exopolysaccharide production protein YjbE 1 79 2.0E-28 T 10-03-2017 IPR025858 Exopolysaccharide production protein YjbE RG49_RS11830 74fa5333babac70fe76a3620cadb267f 237 Pfam PF13099 Domain of unknown function (DUF3944) 5 39 3.7E-15 T 10-03-2017 IPR025217 Domain of unknown function DUF3944 RG49_RS11830 74fa5333babac70fe76a3620cadb267f 237 Pfam PF03981 Ubiquinol-cytochrome C chaperone 58 220 3.6E-23 T 10-03-2017 IPR021150 Ubiquinol-cytochrome c chaperone/UPF0174 RG49_RS02700 6f698d5bc86f0c32304d795039bdfc82 787 Gene3D G3DSA:1.10.443.10 445 552 1.1E-5 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02700 6f698d5bc86f0c32304d795039bdfc82 787 Gene3D G3DSA:1.10.443.10 239 329 1.1E-5 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS02700 6f698d5bc86f0c32304d795039bdfc82 787 SUPERFAMILY SSF56349 498 552 7.65E-5 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS16905 c38a51b02bc41e134984cdbaa5aa2a34 255 SUPERFAMILY SSF141868 26 249 5.1E-30 T 10-03-2017 IPR001633 EAL domain RG49_RS16905 c38a51b02bc41e134984cdbaa5aa2a34 255 SMART SM00052 7 247 1.7E-55 T 10-03-2017 IPR001633 EAL domain RG49_RS16905 c38a51b02bc41e134984cdbaa5aa2a34 255 Gene3D G3DSA:3.20.20.450 33 250 4.7E-25 T 10-03-2017 IPR001633 EAL domain RG49_RS16905 c38a51b02bc41e134984cdbaa5aa2a34 255 Pfam PF00563 EAL domain 27 242 4.4E-29 T 10-03-2017 IPR001633 EAL domain RG49_RS12160 72eaebd16b79127ad9b4939ef26606df 550 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 548 2.1E-159 T 10-03-2017 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 RG49_RS12160 72eaebd16b79127ad9b4939ef26606df 550 Pfam PF00999 Sodium/hydrogen exchanger family 7 419 1.5E-66 T 10-03-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 RG49_RS09240 5ff4c08cb3c6470566d0e7860c59fc50 114 ProDom PD073772 MEMBRANE TRANSMEMBRANE YAIZ INNER ECS0430 GENOME 45 114 2.0E-35 T 10-03-2017 IPR020490 Uncharacterised protein family YaiZ RG49_RS09240 5ff4c08cb3c6470566d0e7860c59fc50 114 Pfam PF10953 Protein of unknown function (DUF2754) 45 114 6.6E-47 T 10-03-2017 IPR020490 Uncharacterised protein family YaiZ RG49_RS19265 24c4f8cab04028b26f3c946b6acbbb3d 321 Pfam PF03741 Integral membrane protein TerC family 80 282 8.5E-57 T 10-03-2017 IPR005496 Integral membrane protein TerC GO:0016021 RG49_RS19265 24c4f8cab04028b26f3c946b6acbbb3d 321 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 7 311 5.2E-121 T 10-03-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 RG49_RS05780 95c1e9e66d0834c4960ed6e96cc07b99 248 Pfam PF06251 Capsule biosynthesis GfcC 21 247 9.3E-89 T 10-03-2017 IPR010425 Domain of unknown function DUF1017 RG49_RS07065 b44cacfa6f04af42d5cc1336e756855c 377 Pfam PF12698 ABC-2 family transporter protein 29 370 3.3E-38 T 10-03-2017 RG49_RS21885 cc139ef31d9be4c201f103a1f16f2f09 95 ProDom PD065621 DEREPRESSION EARLY EPSILON BACTERIOPHAGE HELPER 1 95 1.0E-49 T 10-03-2017 IPR020492 Derepression protein epsilon RG49_RS03170 e7ee53c8ce3b3cee26edca768f288949 73 Pfam PF10753 Protein of unknown function (DUF2566) 20 73 2.3E-27 T 10-03-2017 IPR019689 Toxin GhoT/OrtT RG49_RS06660 ed28a38cb72ea8427b5956a32b14998b 67 Pfam PF05489 Phage Tail Protein X 1 59 3.0E-33 T 10-03-2017 IPR008861 Phage Tail Protein X-like RG49_RS04840 ffd449597ed4823ef5acc583e636187c 111 Pfam PF16456 YmgD protein 28 109 1.7E-48 T 10-03-2017 IPR032497 Uncharacterised protein YmgD RG49_RS13840 e5e319058be3c56ab8dbb16668312b25 165 Pfam PF04345 Chorismate lyase 18 165 9.5E-31 T 10-03-2017 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 RG49_RS13840 e5e319058be3c56ab8dbb16668312b25 165 SUPERFAMILY SSF64288 6 165 5.39E-47 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS13840 e5e319058be3c56ab8dbb16668312b25 165 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 12 165 25.742 T 10-03-2017 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 RG49_RS13840 e5e319058be3c56ab8dbb16668312b25 165 Gene3D G3DSA:3.40.1410.10 3 165 5.3E-58 T 10-03-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain RG49_RS08645 1956a8e47f72b42f52110c328f394d60 430 Pfam PF13520 Amino acid permease 13 396 1.5E-28 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS08645 1956a8e47f72b42f52110c328f394d60 430 PIRSF PIRSF006060 1 428 1.3E-48 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS24465 034812e0808f904f3a4bfabed5cd83dc 132 Hamap MF_01144 UPF0299 membrane protein YohJ [yohJ]. 4 123 23.864 T 10-03-2017 IPR022957 Uncharacterised protein family UPF0299 RG49_RS24465 034812e0808f904f3a4bfabed5cd83dc 132 Pfam PF03788 LrgA family 23 113 1.2E-28 T 10-03-2017 IPR005538 LrgA/CidA family GO:0016021 RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 425 1.1E-206 T 10-03-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 SUPERFAMILY SSF53383 2 425 3.6E-138 T 10-03-2017 IPR015424 Pyridoxal phosphate-dependent transferase RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 Pfam PF00202 Aminotransferase class-III 32 397 6.3E-79 T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 108.843 T 10-03-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 Gene3D G3DSA:3.90.1150.10 2 69 8.0E-46 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 Gene3D G3DSA:3.90.1150.10 319 425 8.0E-46 T 10-03-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 Gene3D G3DSA:3.40.640.10 70 315 4.0E-83 T 10-03-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 RG49_RS11055 a27422463ab38e54b64666e90d5e44b5 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 10-03-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 RG49_RS12245 64ebf211c2df241d1e2cc73dd08a01e7 67 Pfam PF04328 Protein of unknown function (DUF466) 5 67 8.0E-28 T 10-03-2017 IPR007423 Protein of unknown function DUF466 RG49_RS10400 49c5d5fd2df498f45dde0727b6a1c1c3 66 SUPERFAMILY SSF47413 1 61 9.56E-12 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS10400 49c5d5fd2df498f45dde0727b6a1c1c3 66 Gene3D G3DSA:1.10.260.40 1 63 5.6E-17 T 10-03-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 RG49_RS10400 49c5d5fd2df498f45dde0727b6a1c1c3 66 Pfam PF14549 DNA-binding transcriptional regulator Cro 3 62 4.7E-12 T 10-03-2017 RG49_RS20555 26909ae862b272187e42c0b14a1c15d3 398 SUPERFAMILY SSF53686 34 354 1.31E-61 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS20555 26909ae862b272187e42c0b14a1c15d3 398 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 23 391 1.3E-210 T 10-03-2017 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 RG49_RS20555 26909ae862b272187e42c0b14a1c15d3 398 Gene3D G3DSA:3.40.50.1100 114 390 2.8E-37 T 10-03-2017 RG49_RS20555 26909ae862b272187e42c0b14a1c15d3 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 41 375 7.4E-50 T 10-03-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme RG49_RS20555 26909ae862b272187e42c0b14a1c15d3 398 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 6 392 1.2E-196 T 10-03-2017 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 RG49_RS10650 dbcd574fb043ee821b7e4088565af98a 360 Pfam PF06996 Type VI secretion, VasB, ImpH, VC_A0111 36 346 1.4E-84 T 10-03-2017 IPR010732 Type VI secretion, TssG-like RG49_RS10650 dbcd574fb043ee821b7e4088565af98a 360 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 34 346 8.4E-105 T 10-03-2017 IPR010732 Type VI secretion, TssG-like RG49_RS07705 bff477e1fbfef98b7a6004d63850573f 468 Pfam PF03573 outer membrane porin, OprD family 33 430 2.1E-25 T 10-03-2017 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 RG49_RS07705 bff477e1fbfef98b7a6004d63850573f 468 Gene3D G3DSA:2.40.160.10 38 468 2.2E-50 T 10-03-2017 IPR023614 Porin domain RG49_RS23275 b07a894e3f230acc90c1a5273123d953 211 Pfam PF10938 YfdX protein 56 206 2.6E-46 T 10-03-2017 IPR021236 Uncharacterised protein family YfdX RG49_RS17220 5a422db384aafff6e9de57f0759b81fb 81 SUPERFAMILY SSF64307 5 80 9.03E-28 T 10-03-2017 IPR001455 TusA-like domain RG49_RS17220 5a422db384aafff6e9de57f0759b81fb 81 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 10-03-2017 IPR001455 TusA-like domain RG49_RS17220 5a422db384aafff6e9de57f0759b81fb 81 Pfam PF01206 Sulfurtransferase TusA 10 79 2.1E-25 T 10-03-2017 IPR001455 TusA-like domain RG49_RS17220 5a422db384aafff6e9de57f0759b81fb 81 Gene3D G3DSA:3.30.110.40 6 80 7.2E-32 T 10-03-2017 IPR001455 TusA-like domain RG49_RS17220 5a422db384aafff6e9de57f0759b81fb 81 Hamap MF_00413 Sulfurtransferase TusA [tusA]. 3 81 29.938 T 10-03-2017 IPR022931 Sulphurtransferase TusA GO:0016783 RG49_RS16820 311aecf1c44bf620420d5934951323ee 35 Pfam PF13940 Toxin Ldr, type I toxin-antitoxin system 1 35 4.6E-27 T 10-03-2017 IPR025253 Type I toxin-antitoxin system, toxin Ldr RG49_RS09080 9423b535b2adce32a0371dc85f4279dc 115 Pfam PF01844 HNH endonuclease 27 75 6.4E-12 T 10-03-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 RG49_RS09080 9423b535b2adce32a0371dc85f4279dc 115 SMART SM00507 15 70 3.2E-6 T 10-03-2017 IPR003615 HNH nuclease RG49_RS09390 2932d3b4e9fdac8bc4bfe81ba6c920bd 314 SUPERFAMILY SSF53213 5 185 9.42E-71 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09390 2932d3b4e9fdac8bc4bfe81ba6c920bd 314 SUPERFAMILY SSF53213 230 310 9.42E-71 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09390 2932d3b4e9fdac8bc4bfe81ba6c920bd 314 Hamap MF_01653 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase [mhpB]. 1 313 54.711 T 10-03-2017 IPR023789 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase GO:0005506|GO:0019439|GO:0047070|GO:0055114 KEGG: 00360+1.13.11.16|MetaCyc: PWY-6690 RG49_RS09390 2932d3b4e9fdac8bc4bfe81ba6c920bd 314 Gene3D G3DSA:3.40.830.10 7 187 4.1E-86 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09390 2932d3b4e9fdac8bc4bfe81ba6c920bd 314 Gene3D G3DSA:3.40.830.10 232 312 4.1E-86 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS09390 2932d3b4e9fdac8bc4bfe81ba6c920bd 314 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 306 3.4E-90 T 10-03-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 RG49_RS24505 dacf8958b65df1f1a5cefd58154fc07b 195 Pfam PF06930 Protein of unknown function (DUF1282) 7 177 5.0E-44 T 10-03-2017 IPR009698 Protein of unknown function DUF1282 RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.8E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.8E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 8.8E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.8E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 8.8E-19 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.6E-9 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.6E-9 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.6E-9 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 Pfam PF00106 short chain dehydrogenase 3 197 1.5E-48 T 10-03-2017 IPR002347 Short-chain dehydrogenase/reductase SDR RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 SUPERFAMILY SSF51735 2 258 8.92E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 10-03-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 RG49_RS21560 9e97efd3d0b0906c6c7b160e25b92b4c 259 Gene3D G3DSA:3.40.50.720 2 256 3.5E-63 T 10-03-2017 IPR016040 NAD(P)-binding domain RG49_RS03580 8600e930a75b5e2292ce1360d88628b5 433 Pfam PF03237 Terminase-like family 23 416 2.5E-41 T 10-03-2017 IPR004921 Terminase, large subunit RG49_RS07565 0f5051187e959e90d1fde23cab880c6d 353 Pfam PF13808 DDE_Tnp_1-associated 1 69 9.9E-23 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS07565 0f5051187e959e90d1fde23cab880c6d 353 Pfam PF01609 Transposase DDE domain 77 318 1.7E-31 T 10-03-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 RG49_RS05565 107030cbb72fb262decf0411880b083f 672 Pfam PF14883 Hypothetical glycosyl hydrolase family 13 318 645 1.1E-142 T 10-03-2017 IPR032772 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal RG49_RS05565 107030cbb72fb262decf0411880b083f 672 SUPERFAMILY SSF88713 224 346 1.45E-35 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS05565 107030cbb72fb262decf0411880b083f 672 SUPERFAMILY SSF88713 65 196 1.45E-35 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS05565 107030cbb72fb262decf0411880b083f 672 Pfam PF01522 Polysaccharide deacetylase 102 270 1.5E-30 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS05565 107030cbb72fb262decf0411880b083f 672 Gene3D G3DSA:3.20.20.370 74 333 2.9E-25 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS05565 107030cbb72fb262decf0411880b083f 672 TIGRFAM TIGR03938 deacetyl_PgaB: poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 49 665 4.7E-270 T 10-03-2017 IPR023854 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB GO:0016810|GO:0042710 RG49_RS13800 4d1307ac9a78a32c71b172790fb90c0c 171 SUPERFAMILY SSF46785 12 144 5.85E-34 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13800 4d1307ac9a78a32c71b172790fb90c0c 171 Gene3D G3DSA:1.10.10.10 12 83 5.7E-15 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS13800 4d1307ac9a78a32c71b172790fb90c0c 171 Pfam PF01475 Ferric uptake regulator family 20 138 5.9E-15 T 10-03-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 RG49_RS05720 0d0916b0b0f67c050f52508bae942707 390 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 11 184 9.9E-68 T 10-03-2017 IPR005126 NapC/NirT cytochrome c, N-terminal RG49_RS05720 0d0916b0b0f67c050f52508bae942707 390 SUPERFAMILY SSF48695 8 185 2.84E-52 T 10-03-2017 IPR011031 Multihaem cytochrome RG49_RS05720 0d0916b0b0f67c050f52508bae942707 390 TIGRFAM TIGR02162 torC: trimethylamine-N-oxide reductase c-type cytochrome TorC 2 383 3.8E-199 T 10-03-2017 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 RG49_RS05720 0d0916b0b0f67c050f52508bae942707 390 PIRSF PIRSF000014 1 383 6.7E-184 T 10-03-2017 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 RG49_RS05720 0d0916b0b0f67c050f52508bae942707 390 Gene3D G3DSA:1.10.3820.10 328 333 1.7E-29 T 10-03-2017 RG49_RS05720 0d0916b0b0f67c050f52508bae942707 390 Gene3D G3DSA:1.10.3820.10 10 185 1.7E-29 T 10-03-2017 RG49_RS09875 bc044919ecf19ff1fc1d4d905e7dcb9d 208 Pfam PF11726 Protein of unknown function (DUF3296) 18 204 6.2E-66 T 10-03-2017 IPR021723 Inovirus Gp2 RG49_RS19325 a66343ae1ae0ed0862055ecd995a3a4f 149 SUPERFAMILY SSF51197 3 142 2.28E-22 T 10-03-2017 RG49_RS19325 a66343ae1ae0ed0862055ecd995a3a4f 149 Pfam PF04074 Domain of unknown function (DUF386) 3 139 3.1E-24 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS19325 a66343ae1ae0ed0862055ecd995a3a4f 149 Gene3D G3DSA:2.60.120.370 3 141 6.3E-17 T 10-03-2017 IPR004375 YhcH/YjgK/YiaL family RG49_RS25040 3c1d3fe7c4c0c7fb718fd7e90f3dffee 353 Pfam PF00534 Glycosyl transferases group 1 172 323 3.1E-25 T 10-03-2017 IPR001296 Glycosyl transferase, family 1 RG49_RS25040 3c1d3fe7c4c0c7fb718fd7e90f3dffee 353 Gene3D G3DSA:3.40.50.2000 145 311 7.9E-22 T 10-03-2017 RG49_RS25040 3c1d3fe7c4c0c7fb718fd7e90f3dffee 353 SUPERFAMILY SSF53756 3 349 3.56E-55 T 10-03-2017 RG49_RS12120 97a11c6d3d5fcf9f2d7cb79fe023ce71 256 Pfam PF06738 Putative threonine/serine exporter 11 250 1.1E-69 T 10-03-2017 IPR010619 Putative threonine/serine exporter RG49_RS24235 a5fa7747215ae6b55959a878eed53a43 396 Pfam PF07690 Major Facilitator Superfamily 16 358 2.4E-45 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS24235 a5fa7747215ae6b55959a878eed53a43 396 SUPERFAMILY SSF103473 8 395 1.44E-69 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS24235 a5fa7747215ae6b55959a878eed53a43 396 TIGRFAM TIGR00880 2_A_01_02: multidrug resistance protein 52 188 2.0E-42 T 10-03-2017 IPR004734 Multidrug resistance protein GO:0015238|GO:0015893|GO:0016021 Reactome: R-HSA-442660 RG49_RS24235 a5fa7747215ae6b55959a878eed53a43 396 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 390 7.4E-163 T 10-03-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 RG49_RS24235 a5fa7747215ae6b55959a878eed53a43 396 Gene3D G3DSA:1.20.1250.20 12 194 2.7E-33 T 10-03-2017 RG49_RS24235 a5fa7747215ae6b55959a878eed53a43 396 Gene3D G3DSA:1.20.1250.20 211 393 3.0E-10 T 10-03-2017 RG49_RS03570 db9e9e934f284d754ff12a04f78ef1f5 370 PIRSF PIRSF034565 6 370 6.3E-133 T 10-03-2017 IPR017029 Putative phage head morphogenesis protein RG49_RS03570 db9e9e934f284d754ff12a04f78ef1f5 370 Pfam PF04233 Phage Mu protein F like protein 153 273 3.4E-8 T 10-03-2017 IPR006528 Phage head morphogenesis domain RG49_RS12540 fd3ffc7612ea6ffeaa68c2fce7bfaac9 186 Pfam PF00239 Resolvase, N terminal domain 4 142 1.4E-36 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS12540 fd3ffc7612ea6ffeaa68c2fce7bfaac9 186 SUPERFAMILY SSF53041 1 142 4.05E-40 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS12540 fd3ffc7612ea6ffeaa68c2fce7bfaac9 186 Gene3D G3DSA:1.10.10.60 144 181 1.6E-4 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS12540 fd3ffc7612ea6ffeaa68c2fce7bfaac9 186 SMART SM00857 3 142 1.0E-50 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS12540 fd3ffc7612ea6ffeaa68c2fce7bfaac9 186 Gene3D G3DSA:3.40.50.1390 1 124 1.3E-35 T 10-03-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 RG49_RS04565 01594cfc8ebd1478000babc7e0515264 130 Pfam PF04247 Invasion gene expression up-regulator, SirB 6 127 1.5E-34 T 10-03-2017 IPR007360 Invasion gene expression up-regulator, SirB RG49_RS04565 01594cfc8ebd1478000babc7e0515264 130 PIRSF PIRSF005610 1 125 7.4E-19 T 10-03-2017 IPR007360 Invasion gene expression up-regulator, SirB RG49_RS10340 ee4c59573b107b732e73bdfe4eb41d2f 108 Pfam PF05106 Phage holin family (Lysis protein S) 5 102 1.1E-25 T 10-03-2017 IPR006481 Bacteriophage lambda, GpS, holin RG49_RS10340 ee4c59573b107b732e73bdfe4eb41d2f 108 TIGRFAM TIGR01594 holin_lambda: phage holin, lambda family 1 105 4.8E-36 T 10-03-2017 IPR006481 Bacteriophage lambda, GpS, holin RG49_RS18875 d1085cd555e31f30dc7869b9c267bdd5 167 Pfam PF13508 Acetyltransferase (GNAT) domain 44 123 2.4E-10 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS18875 d1085cd555e31f30dc7869b9c267bdd5 167 SUPERFAMILY SSF55729 1 163 9.78E-25 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS18875 d1085cd555e31f30dc7869b9c267bdd5 167 Gene3D G3DSA:3.40.630.30 17 127 6.0E-19 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS13315 a4d2334bb8fdfdcffe5daa6acb9eda80 76 Pfam PF06902 Divergent 4Fe-4S mono-cluster 13 76 6.5E-29 T 10-03-2017 IPR010693 Divergent 4Fe-4S mono-cluster RG49_RS04135 2f7611af1672614622d32d671b386112 57 Hamap MF_01641 UPF0509 protein YciZ [yciZ]. 1 57 25.98 T 10-03-2017 IPR020887 Uncharacterised protein family UPF0509 RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 Gene3D G3DSA:3.40.50.300 164 202 3.9E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 Gene3D G3DSA:3.40.50.300 42 63 3.9E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 SUPERFAMILY SSF52540 165 209 2.19E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 SUPERFAMILY SSF52540 45 75 2.19E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 Gene3D G3DSA:3.40.50.300 233 336 0.001 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 Gene3D G3DSA:3.40.50.300 64 143 0.001 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 SUPERFAMILY SSF52540 239 330 5.9E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS02280 ec757df833f7189f885071bf66c62cff 588 SUPERFAMILY SSF52540 44 111 5.9E-5 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS05125 49abb01d1a4ae381d598799580d8c3fa 125 Pfam PF07233 Protein of unknown function (DUF1425) 34 124 4.5E-26 T 10-03-2017 IPR010824 Protein of unknown function DUF1425 RG49_RS13915 7c9637b99147977ac6ce9c9610667154 698 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 30 691 8.8E-271 T 10-03-2017 IPR010344 Exopolysaccharide biosynthesis protein YbjH RG49_RS01200 750c76de612c0778c79a0e84a38ad998 206 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 89 1.1E-9 T 10-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 RG49_RS01200 750c76de612c0778c79a0e84a38ad998 206 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 89 - T 10-03-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 RG49_RS03255 c3ec39d379cb8ce3f605174e5ba70eda 222 Pfam PF11769 Protein of unknown function (DUF3313) 17 213 1.4E-57 T 10-03-2017 IPR021747 Protein of unknown function DUF3313 RG49_RS16175 10ad4b48fceee46064d5710b2cf281c5 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 9.4E-44 T 10-03-2017 IPR013527 YicC-like, N-terminal RG49_RS16175 10ad4b48fceee46064d5710b2cf281c5 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 287 3.0E-34 T 10-03-2017 IPR013551 Domain of unknown function DUF1732 RG49_RS16175 10ad4b48fceee46064d5710b2cf281c5 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 287 1.2E-139 T 10-03-2017 IPR005229 Conserved hypothetical protein CHP00255 RG49_RS13445 7a4ac01db26900e8df8cfd7017aa84f2 147 SUPERFAMILY SSF54593 2 139 1.08E-28 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS13445 7a4ac01db26900e8df8cfd7017aa84f2 147 Gene3D G3DSA:3.10.180.10 7 143 7.0E-41 T 10-03-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase RG49_RS13445 7a4ac01db26900e8df8cfd7017aa84f2 147 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 138 1.1E-6 T 10-03-2017 IPR028973 PhnB-like RG49_RS04065 96dd1ad5815b580d8bb84861a9e0412b 461 PIRSF PIRSF006060 2 459 6.9E-78 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS04065 96dd1ad5815b580d8bb84861a9e0412b 461 Pfam PF00324 Amino acid permease 27 429 3.0E-40 T 10-03-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 RG49_RS06800 d94d303f349fd6b56cbd2781dd092aa5 198 SUPERFAMILY SSF48317 1 196 6.02E-42 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS06800 d94d303f349fd6b56cbd2781dd092aa5 198 SMART SM00014 57 165 6.0E-32 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS06800 d94d303f349fd6b56cbd2781dd092aa5 198 Pfam PF01569 PAP2 superfamily 58 166 2.0E-13 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS06800 d94d303f349fd6b56cbd2781dd092aa5 198 Gene3D G3DSA:1.20.144.10 3 165 1.4E-27 T 10-03-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase RG49_RS24000 7ab5c96ce88776428c8b6e0085c2e8f8 216 SUPERFAMILY SSF100950 2 211 7.73E-68 T 10-03-2017 RG49_RS24000 7ab5c96ce88776428c8b6e0085c2e8f8 216 Gene3D G3DSA:3.40.810.20 3 209 6.9E-84 T 10-03-2017 RG49_RS24000 7ab5c96ce88776428c8b6e0085c2e8f8 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 204 1.9E-92 T 10-03-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 RG49_RS24000 7ab5c96ce88776428c8b6e0085c2e8f8 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 43 51 - T 10-03-2017 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 RG49_RS24000 7ab5c96ce88776428c8b6e0085c2e8f8 216 Pfam PF01144 Coenzyme A transferase 5 179 1.0E-37 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS24000 7ab5c96ce88776428c8b6e0085c2e8f8 216 SMART SM00882 5 198 2.8E-65 T 10-03-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 RG49_RS19830 ff7234668f7d177e4796f1335e1a1df7 230 SUPERFAMILY SSF52540 6 224 9.31E-14 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS19830 ff7234668f7d177e4796f1335e1a1df7 230 Gene3D G3DSA:3.40.50.300 8 221 2.3E-24 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22355 d5b99aaccb74912ff045ab72909bc3e4 140 Pfam PF07681 DoxX 16 97 1.6E-16 T 10-03-2017 IPR032808 DoxX family RG49_RS00580 9eb2861ceec31a7e766a83fa0a09eaa1 188 Pfam PF00857 Isochorismatase family 9 182 2.0E-38 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS00580 9eb2861ceec31a7e766a83fa0a09eaa1 188 SUPERFAMILY SSF52499 4 188 2.75E-51 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS00580 9eb2861ceec31a7e766a83fa0a09eaa1 188 Gene3D G3DSA:3.40.50.850 3 185 4.6E-52 T 10-03-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 RG49_RS05280 3e8d86b7a557f5f3957a7efcc60aeb06 138 PIRSF PIRSF002889 1 137 3.4E-44 T 10-03-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 RG49_RS05280 3e8d86b7a557f5f3957a7efcc60aeb06 138 Pfam PF00460 Flagella basal body rod protein 9 39 2.2E-12 T 10-03-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 RG49_RS05280 3e8d86b7a557f5f3957a7efcc60aeb06 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 10-03-2017 IPR019776 Flagellar basal body rod protein, conserved site RG49_RS05280 3e8d86b7a557f5f3957a7efcc60aeb06 138 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 135 7.6E-50 T 10-03-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 RG49_RS13795 1f00e407bc95c71e769464d48da1906c 84 ProDom PD060861 YJBL ECS5030 1 84 2.0E-42 T 10-03-2017 IPR020276 Uncharacterised protein family, YjbL RG49_RS12800 23d5e4c5198cdddf89d36c990ed28af9 185 Pfam PF09695 Bacterial protein of unknown function (YtfJ_HI0045) 24 181 2.6E-75 T 10-03-2017 IPR006513 Conserved hypothetical protein CHP01626, YtfJ RG49_RS12800 23d5e4c5198cdddf89d36c990ed28af9 185 TIGRFAM TIGR01626 ytfJ_HI0045: conserved hypothetical protein YtfJ-family, TIGR01626 1 183 1.2E-92 T 10-03-2017 IPR006513 Conserved hypothetical protein CHP01626, YtfJ RG49_RS08630 22cceb8ea8572d920b6ea0113afe5ddb 152 Gene3D G3DSA:1.20.1250.20 34 84 5.0E-4 T 10-03-2017 RG49_RS08630 22cceb8ea8572d920b6ea0113afe5ddb 152 Gene3D G3DSA:2.40.50.140 94 148 7.5E-10 T 10-03-2017 IPR012340 Nucleic acid-binding, OB-fold RG49_RS08630 22cceb8ea8572d920b6ea0113afe5ddb 152 SUPERFAMILY SSF141322 95 150 9.42E-5 T 10-03-2017 RG49_RS08630 22cceb8ea8572d920b6ea0113afe5ddb 152 Pfam PF01957 NfeD-like C-terminal, partner-binding 13 149 4.3E-24 T 10-03-2017 IPR002810 NfeD-like, C-terminal domain RG49_RS02300 7e77282f303f9313a4d64d3c781d2f1a 349 Pfam PF06147 Protein of unknown function (DUF968) 131 346 3.9E-80 T 10-03-2017 IPR010373 Protein of unknown function DUF968 RG49_RS02300 7e77282f303f9313a4d64d3c781d2f1a 349 SMART SM00507 266 315 1.8E-5 T 10-03-2017 IPR003615 HNH nuclease RG49_RS09780 8cd29ab59e3e10f4b1fe7b201ae67964 146 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 8 141 9.1E-33 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS09735 8cd29ab59e3e10f4b1fe7b201ae67964 146 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 8 141 9.1E-33 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS07070 9cc81d16a4ada6aa83fe23a5941d98e1 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 290 309 2.3E-6 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS07070 9cc81d16a4ada6aa83fe23a5941d98e1 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 253 277 2.3E-6 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS07070 9cc81d16a4ada6aa83fe23a5941d98e1 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 310 329 2.3E-6 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS07070 9cc81d16a4ada6aa83fe23a5941d98e1 368 Pfam PF12698 ABC-2 family transporter protein 25 358 6.5E-49 T 10-03-2017 RG49_RS22990 b46f10ef56added92a63b1b09f0f6dac 285 Hamap MF_02108 HTH-type transcriptional regulator MurR [murR]. 1 285 65.47 T 10-03-2017 IPR022821 Transcription regulator HTH, MurR RG49_RS22990 b46f10ef56added92a63b1b09f0f6dac 285 SUPERFAMILY SSF53697 111 272 8.6E-38 T 10-03-2017 RG49_RS22990 b46f10ef56added92a63b1b09f0f6dac 285 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.2E-27 T 10-03-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 RG49_RS22990 b46f10ef56added92a63b1b09f0f6dac 285 Gene3D G3DSA:1.10.10.10 3 75 1.0E-20 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS22990 b46f10ef56added92a63b1b09f0f6dac 285 Gene3D G3DSA:3.40.50.10490 101 276 2.0E-37 T 10-03-2017 RG49_RS22990 b46f10ef56added92a63b1b09f0f6dac 285 Pfam PF01380 SIS domain 132 260 3.7E-22 T 10-03-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 RG49_RS22990 b46f10ef56added92a63b1b09f0f6dac 285 SUPERFAMILY SSF46689 4 74 1.59E-15 T 10-03-2017 IPR009057 Homeodomain-like GO:0003677 RG49_RS04540 3c778838db426eafafa86324b8c1dd40 366 Pfam PF01699 Sodium/calcium exchanger protein 223 364 1.6E-9 T 10-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 RG49_RS04540 3c778838db426eafafa86324b8c1dd40 366 Pfam PF01699 Sodium/calcium exchanger protein 40 190 3.0E-14 T 10-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 RG49_RS04540 3c778838db426eafafa86324b8c1dd40 366 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 1 365 1.1E-128 T 10-03-2017 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 RG49_RS02220 b14d40e17a6a48d8c154503e5f2f50fe 51 ProDom PD019047 YDFA YDAF PROPHAGE ECS2210 ECS2767 ECS1505 STY2067 1 49 1.0E-20 T 10-03-2017 IPR009821 Protein of unknown function DUF1391 RG49_RS02220 b14d40e17a6a48d8c154503e5f2f50fe 51 Pfam PF07151 Protein of unknown function (DUF1391) 3 48 1.9E-32 T 10-03-2017 IPR009821 Protein of unknown function DUF1391 RG49_RS11240 8ebca0738a83e782708c9b4b890d1b23 172 Pfam PF09691 Type II secretion system pilotin lipoprotein (PulS_OutS) 81 163 5.6E-8 T 10-03-2017 IPR019114 Chaperone lipoprotein, PulS/OutS-like RG49_RS11240 8ebca0738a83e782708c9b4b890d1b23 172 ProDom PD074041 YACC EXPORTED PRECURSOR SIGNAL PERIPLASMIC Y0776 SIMILAR ECS0126 STY0189 ESCHERICHIA 58 172 3.0E-63 T 10-03-2017 RG49_RS13200 49cae799eb058d52b40eebde3955cf4a 289 Pfam PF15922 YjeJ-like 1 283 3.9E-155 T 10-03-2017 IPR031810 YjeJ-like RG49_RS21825 99720b29b6e187376d41c1efe404450d 160 ProDom PD094182 YPJC ECS3517 1 160 4.0E-79 T 10-03-2017 IPR020227 Uncharacterised protein family, YpjC RG49_RS06120 bbf5f34fe903483125d29ab15be37248 234 Hamap MF_01802 Chromosome partition protein MukE [mukE]. 10 234 48.74 T 10-03-2017 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 RG49_RS06120 bbf5f34fe903483125d29ab15be37248 234 Pfam PF04288 MukE-like family 10 230 5.7E-126 T 10-03-2017 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 RG49_RS14135 696a63d9107a6a09a9347fc1818cc273 256 Gene3D G3DSA:3.20.20.70 1 253 1.1E-64 T 10-03-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 RG49_RS14135 696a63d9107a6a09a9347fc1818cc273 256 SUPERFAMILY SSF110399 1 235 6.93E-82 T 10-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 RG49_RS14135 696a63d9107a6a09a9347fc1818cc273 256 Hamap MF_00443 Thiazole synthase [thiG]. 1 253 42.938 T 10-03-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 RG49_RS14135 696a63d9107a6a09a9347fc1818cc273 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 247 2.0E-110 T 10-03-2017 RG49_RS18905 3182b332d3bf53110c047a967d45302d 191 SMART SM00749 129 191 9.4E-7 T 10-03-2017 IPR014004 Transport-associated and nodulation domain, bacteria RG49_RS18905 3182b332d3bf53110c047a967d45302d 191 SMART SM00749 51 114 8.0E-13 T 10-03-2017 IPR014004 Transport-associated and nodulation domain, bacteria RG49_RS18905 3182b332d3bf53110c047a967d45302d 191 Pfam PF04972 BON domain 124 188 3.2E-18 T 10-03-2017 IPR007055 BON domain RG49_RS18905 3182b332d3bf53110c047a967d45302d 191 Pfam PF04972 BON domain 46 113 2.8E-14 T 10-03-2017 IPR007055 BON domain RG49_RS01140 f6a126df007e2b9f937252b3e10d7160 452 SUPERFAMILY SSF103473 9 449 8.11E-66 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS01140 f6a126df007e2b9f937252b3e10d7160 452 Pfam PF00083 Sugar (and other) transporter 55 451 1.9E-35 T 10-03-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 RG49_RS01140 f6a126df007e2b9f937252b3e10d7160 452 Gene3D G3DSA:1.20.1250.20 262 443 5.0E-19 T 10-03-2017 RG49_RS01140 f6a126df007e2b9f937252b3e10d7160 452 Gene3D G3DSA:1.20.1250.20 18 203 2.1E-19 T 10-03-2017 RG49_RS03640 f8dc7d6199cc7b6ca46c8aca585022bf 180 Pfam PF06576 Protein of unknown function (DUF1133) 1 175 4.8E-104 T 10-03-2017 IPR010557 Protein of unknown function DUF1133 RG49_RS13000 cbc23639b77a5f5c666dbfe3a761a41c 219 Pfam PF10679 Protein of unknown function (DUF2491) 4 215 1.8E-69 T 10-03-2017 IPR019621 Protein of unknown function DUF2491 RG49_RS07090 90d80f7284488e046155561fad0810c0 318 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 21 295 1.3E-16 T 10-03-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD RG49_RS09335 42aa88b8937af3dbc7154b9a93528a6f 91 Pfam PF02583 Metal-sensitive transcriptional repressor 7 87 4.5E-22 T 10-03-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 RG49_RS18605 6aa8c3f6bc3d4c9b66bfec303e76f0f9 210 Pfam PF10707 PhoP regulatory network protein YrbL 2 185 6.0E-63 T 10-03-2017 IPR019647 PhoP regulatory network protein YrbL RG49_RS18605 6aa8c3f6bc3d4c9b66bfec303e76f0f9 210 SUPERFAMILY SSF56112 13 152 9.09E-9 T 10-03-2017 IPR011009 Protein kinase-like domain RG49_RS19750 1dc4fbae30f91e3c3e48867ad308b7d2 346 SUPERFAMILY SSF51430 13 331 5.89E-89 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS19750 1dc4fbae30f91e3c3e48867ad308b7d2 346 Gene3D G3DSA:3.20.20.100 12 331 1.8E-88 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS19750 1dc4fbae30f91e3c3e48867ad308b7d2 346 Pfam PF00248 Aldo/keto reductase family 28 332 3.0E-80 T 10-03-2017 IPR023210 NADP-dependent oxidoreductase domain RG49_RS22745 735ed0fad65923ee541cacd505624655 223 Pfam PF00361 Proton-conducting membrane transporter 136 207 5.2E-7 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22745 735ed0fad65923ee541cacd505624655 223 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 72 107 1.7E-5 T 10-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS06640 4e4c6092dabe0ff12ce48e3e2201732a 142 TIGRFAM TIGR03495 phage_LysB: phage lysis regulatory protein, LysB family 3 136 4.6E-52 T 10-03-2017 IPR020000 Bacteriophage P2, LysB RG49_RS15365 1d3a670d1bfad1175025fba33bbc4a4c 309 Gene3D G3DSA:3.30.470.10 7 130 1.6E-43 T 10-03-2017 RG49_RS15365 1d3a670d1bfad1175025fba33bbc4a4c 309 Gene3D G3DSA:3.20.10.10 135 295 3.0E-58 T 10-03-2017 RG49_RS15365 1d3a670d1bfad1175025fba33bbc4a4c 309 Pfam PF01063 Amino-transferase class IV 36 268 6.0E-51 T 10-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 RG49_RS15365 1d3a670d1bfad1175025fba33bbc4a4c 309 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 223 - T 10-03-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 RG49_RS15365 1d3a670d1bfad1175025fba33bbc4a4c 309 SUPERFAMILY SSF56752 7 308 1.31E-105 T 10-03-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 RG49_RS15365 1d3a670d1bfad1175025fba33bbc4a4c 309 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 10 307 6.9E-148 T 10-03-2017 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108 RG49_RS07700 9119f4702f0f2bb81a8a9f5439748650 108 Pfam PF13982 YbfN-like lipoprotein 20 107 1.9E-48 T 10-03-2017 IPR025727 YbfN-like lipoprotein RG49_RS24405 4291f1df8f9d0dc081231e46a74cf414 385 Pfam PF04235 Protein of unknown function (DUF418) 215 374 7.6E-47 T 10-03-2017 IPR007349 Domain of unknown function DUF418 RG49_RS05750 12d246d8816a6232049dfe3015021a51 76 Pfam PF15939 Putative antitoxin of bacterial toxin-antitoxin system 1 76 1.1E-56 T 10-03-2017 IPR031853 Putative antitoxin YmcE RG49_RS22565 e244bf9d8aef2582df86baee1492a039 332 Pfam PF04796 Plasmid encoded RepA protein 93 268 3.7E-33 T 10-03-2017 IPR006881 Plasmid encoded RepA protein RG49_RS19575 43c25df8e3937e9cf2d501de8338fc94 493 Gene3D G3DSA:1.20.1600.10 15 434 6.1E-95 T 10-03-2017 RG49_RS19575 43c25df8e3937e9cf2d501de8338fc94 493 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 21 443 4.9E-145 T 10-03-2017 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 RG49_RS19575 43c25df8e3937e9cf2d501de8338fc94 493 SUPERFAMILY SSF56954 25 447 2.09E-99 T 10-03-2017 RG49_RS19575 43c25df8e3937e9cf2d501de8338fc94 493 Pfam PF02321 Outer membrane efflux protein 232 427 4.5E-33 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS19575 43c25df8e3937e9cf2d501de8338fc94 493 Pfam PF02321 Outer membrane efflux protein 27 209 3.5E-26 T 10-03-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 RG49_RS02205 1b5b96b92ef6b5633bcb7b2f818fc18e 63 Pfam PF07358 Protein of unknown function (DUF1482) 4 61 4.0E-25 T 10-03-2017 IPR009954 Protein of unknown function DUF1482 RG49_RS02560 bf83c4375b5b050103db9a8628dcecd1 72 Pfam PF13999 MarB protein 6 70 2.8E-34 T 10-03-2017 IPR025732 MarB protein RG49_RS02560 bf83c4375b5b050103db9a8628dcecd1 72 ProDom PD027692 ANTIBIOTIC RESISTANCE MULTIPLE MARB 1 72 1.0E-27 T 10-03-2017 IPR025732 MarB protein RG49_RS09960 ab988e1ca9945565c7af8f22de79b8ff 279 Pfam PF00665 Integrase core domain 108 223 2.5E-32 T 10-03-2017 IPR001584 Integrase, catalytic core GO:0015074 RG49_RS09960 ab988e1ca9945565c7af8f22de79b8ff 279 SUPERFAMILY SSF53098 101 263 1.39E-41 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS09960 ab988e1ca9945565c7af8f22de79b8ff 279 Gene3D G3DSA:3.30.420.10 102 261 1.2E-40 T 10-03-2017 IPR012337 Ribonuclease H-like domain GO:0003676 RG49_RS01590 94908636efdf36c16faa3c2ed0674250 370 Pfam PF01594 Domain of unknown function DUF20 15 344 1.3E-65 T 10-03-2017 IPR002549 Transmembrane protein TqsA-like RG49_RS23095 d013800745a406ed3e2f821f4a0fb62a 254 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 34 254 2.3E-37 T 10-03-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 RG49_RS23095 d013800745a406ed3e2f821f4a0fb62a 254 SUPERFAMILY SSF111364 26 254 2.62E-43 T 10-03-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 RG49_RS02465 2a06ba30b347d4c344828ab10f45fda0 1159 Gene3D G3DSA:2.60.40.10 618 709 1.3E-4 T 10-03-2017 IPR013783 Immunoglobulin-like fold RG49_RS02465 2a06ba30b347d4c344828ab10f45fda0 1159 Pfam PF13550 Putative phage tail protein 330 495 1.7E-40 T 10-03-2017 IPR032876 Tip attachment protein J RG49_RS02465 2a06ba30b347d4c344828ab10f45fda0 1159 SUPERFAMILY SSF49265 617 719 5.7E-6 T 10-03-2017 IPR003961 Fibronectin type III GO:0005515 RG49_RS02465 2a06ba30b347d4c344828ab10f45fda0 1159 Pfam PF09327 Domain of unknown function (DUF1983) 873 953 3.5E-22 T 10-03-2017 IPR015406 Domain of unknown function DUF1983 RG49_RS02465 2a06ba30b347d4c344828ab10f45fda0 1159 Pfam PF12421 Fibronectin type III protein 977 1117 7.3E-41 T 10-03-2017 IPR021034 Domain of unknown function, DUF3672 RG49_RS02465 2a06ba30b347d4c344828ab10f45fda0 1159 SMART SM00060 618 701 0.18 T 10-03-2017 IPR003961 Fibronectin type III GO:0005515 RG49_RS02465 2a06ba30b347d4c344828ab10f45fda0 1159 SMART SM00060 714 798 53.0 T 10-03-2017 IPR003961 Fibronectin type III GO:0005515 RG49_RS17510 978eaef3e69d95f5ca4bdaf0ca640a0a 292 Pfam PF04754 Putative transposase, YhgA-like 8 209 4.9E-88 T 10-03-2017 IPR006842 Transposase (putative), YhgA-like RG49_RS17510 978eaef3e69d95f5ca4bdaf0ca640a0a 292 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 288 2.5E-47 T 10-03-2017 IPR010106 Conserved hypothetical protein CHP01784 RG49_RS10565 5b3a74c3ccac39b6b6ad2d79e078b3be 255 SUPERFAMILY SSF56235 2 253 1.37E-52 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS10565 5b3a74c3ccac39b6b6ad2d79e078b3be 255 Pfam PF13230 Glutamine amidotransferases class-II 1 252 7.9E-115 T 10-03-2017 IPR026869 Putative glutamine amidotransferase type 2 RG49_RS10565 5b3a74c3ccac39b6b6ad2d79e078b3be 255 Gene3D G3DSA:3.60.20.10 1 248 6.9E-68 T 10-03-2017 IPR029055 Nucleophile aminohydrolases, N-terminal RG49_RS13625 3059de4b576ed1ca40f37247ac9576c8 127 TIGRFAM TIGR03147 cyt_nit_nrfF: cytochrome c nitrite reductase, accessory protein NrfF 3 127 7.7E-63 T 10-03-2017 IPR017565 Formate-dependent nitrite reductase complex, subunit NrfF RG49_RS13625 3059de4b576ed1ca40f37247ac9576c8 127 Pfam PF03918 Cytochrome C biogenesis protein 7 126 6.9E-44 T 10-03-2017 IPR005616 CcmH/CycL/Ccl2/NrfF family RG49_RS21875 b691ee57cab5e538cb00e3417dbc1d45 106 ProDom PD070475 P4 PHAGE PROPHAGE-DERIVED CNR-LIKE ORF106 T2655 20 106 3.0E-36 T 10-03-2017 RG49_RS12030 2b76c467e2b232a0a362242579473e14 69 Pfam PF12035 Protein of unknown function (DUF3521) 1 28 1.8E-9 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS15165 ab12975d962de749be008095f7fcca95 848 PIRSF PIRSF001444 1 847 0.0 T 10-03-2017 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 RG49_RS15165 ab12975d962de749be008095f7fcca95 848 Pfam PF01295 Adenylate cyclase, class-I 228 825 6.6E-258 T 10-03-2017 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 RG49_RS15165 ab12975d962de749be008095f7fcca95 848 ProSitePatterns PS01093 Adenylate cyclase class-I signature 2. 598 612 - T 10-03-2017 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 RG49_RS15165 ab12975d962de749be008095f7fcca95 848 Pfam PF12633 Adenylate cyclase NT domain 5 200 4.4E-81 T 10-03-2017 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 RG49_RS15165 ab12975d962de749be008095f7fcca95 848 ProSitePatterns PS01092 Adenylate cyclase class-I signature 1. 242 253 - T 10-03-2017 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 RG49_RS04775 12d5e3d642271de381a19ec3bb6812eb 133 Gene3D G3DSA:2.60.120.380 37 130 3.0E-5 T 10-03-2017 RG49_RS04775 12d5e3d642271de381a19ec3bb6812eb 133 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 48 111 2.5E-7 T 10-03-2017 IPR007280 Peptidase, C-terminal, archaeal/bacterial RG49_RS02875 6333ba099b7dc5ad261d9388411a5567 439 Pfam PF02638 Glycosyl hydrolase-like 10 55 390 2.0E-138 T 10-03-2017 IPR003790 Glycosyl hydrolase-like 10 RG49_RS02875 6333ba099b7dc5ad261d9388411a5567 439 Gene3D G3DSA:3.20.20.80 89 239 2.6E-9 T 10-03-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 RG49_RS02875 6333ba099b7dc5ad261d9388411a5567 439 SUPERFAMILY SSF51445 81 365 1.36E-31 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS10865 78921246262a5771174ba4db0353b5ec 66 Hamap MF_01064 UPF0253 protein YaeP [yaeP]. 1 66 27.209 T 10-03-2017 IPR009624 Uncharacterised protein family UPF0253 RG49_RS10865 78921246262a5771174ba4db0353b5ec 66 ProDom PD054643 UPF0253 YAEP CYTOPLASMIC VP2335 YPO1064.1/Y3113/YP2785 VC0872 VV2574 PBPRA2947 VV11836 1 66 5.0E-27 T 10-03-2017 IPR009624 Uncharacterised protein family UPF0253 RG49_RS10865 78921246262a5771174ba4db0353b5ec 66 Pfam PF06786 Uncharacterised protein family (UPF0253) 2 65 3.4E-34 T 10-03-2017 IPR009624 Uncharacterised protein family UPF0253 RG49_RS20655 24fe21f189d84414e6dde6e15783d1b8 130 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 47 68 3.0E-9 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS20655 24fe21f189d84414e6dde6e15783d1b8 130 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 17 32 3.0E-9 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS20655 24fe21f189d84414e6dde6e15783d1b8 130 SUPERFAMILY SSF160544 3 98 1.26E-25 T 10-03-2017 IPR029025 Type III secretion system substrate exporter, C-terminal RG49_RS20655 24fe21f189d84414e6dde6e15783d1b8 130 Gene3D G3DSA:3.40.1690.10 2 99 2.7E-25 T 10-03-2017 IPR029025 Type III secretion system substrate exporter, C-terminal RG49_RS20655 24fe21f189d84414e6dde6e15783d1b8 130 Pfam PF01312 FlhB HrpN YscU SpaS Family 3 91 4.9E-20 T 10-03-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 RG49_RS13920 bf1144a36a9a230e5b4b6bbc941247f3 245 Pfam PF06251 Capsule biosynthesis GfcC 19 245 1.4E-90 T 10-03-2017 IPR010425 Domain of unknown function DUF1017 RG49_RS04260 a656f81e21bd955cd09a74e9d6759db3 14 Pfam PF08255 Trp-operon Leader Peptide 1 14 3.1E-9 T 10-03-2017 IPR013205 Leader peptide, tryptophan-operon RG49_RS00520 8753591244fe769a57dc9a0a035dfcbd 130 Pfam PF06366 Flagellar protein FlhE 28 130 2.9E-38 T 10-03-2017 IPR009420 Flagellar protein FlhE RG49_RS16675 92010e6a65242879d952d15f1a9a47f3 99 Pfam PF13983 YsaB-like lipoprotein 25 99 4.8E-42 T 10-03-2017 IPR025728 YsaB-like lipoprotein RG49_RS15200 ef7c8f9f239a7a1e7d329e42b11f5abb 59 Pfam PF12035 Protein of unknown function (DUF3521) 11 38 6.2E-7 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS07015 abff3b4bc0880312dc5caa4a683d877d 86 Pfam PF07338 Protein of unknown function (DUF1471) 34 86 1.8E-16 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS07015 abff3b4bc0880312dc5caa4a683d877d 86 Gene3D G3DSA:3.30.1660.10 18 86 1.5E-27 T 10-03-2017 IPR025543 Dodecin-like RG49_RS07015 abff3b4bc0880312dc5caa4a683d877d 86 SUPERFAMILY SSF159871 3 86 4.71E-25 T 10-03-2017 IPR010854 Domain of unknown function DUF1471 RG49_RS22730 df81a014454c091da38351363d0500c4 479 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 119 6.9E-10 T 10-03-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS22730 df81a014454c091da38351363d0500c4 479 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 1.4E-32 T 10-03-2017 RG49_RS22730 df81a014454c091da38351363d0500c4 479 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 1.4E-32 T 10-03-2017 RG49_RS22730 df81a014454c091da38351363d0500c4 479 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 307 319 1.4E-32 T 10-03-2017 RG49_RS22730 df81a014454c091da38351363d0500c4 479 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 155 176 1.4E-32 T 10-03-2017 RG49_RS22730 df81a014454c091da38351363d0500c4 479 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 1.4E-32 T 10-03-2017 RG49_RS22730 df81a014454c091da38351363d0500c4 479 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 1.4E-32 T 10-03-2017 RG49_RS22730 df81a014454c091da38351363d0500c4 479 Pfam PF00361 Proton-conducting membrane transporter 133 413 2.5E-54 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02670 7537482b4af403c10fa62e4fbed1e78b 317 Pfam PF04198 Putative sugar-binding domain 67 316 3.9E-73 T 10-03-2017 IPR007324 Sugar-binding domain, putative GO:0030246 RG49_RS02670 7537482b4af403c10fa62e4fbed1e78b 317 Gene3D G3DSA:3.40.50.1360 73 316 1.7E-68 T 10-03-2017 RG49_RS02670 7537482b4af403c10fa62e4fbed1e78b 317 Gene3D G3DSA:1.10.10.10 31 63 2.0E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02670 7537482b4af403c10fa62e4fbed1e78b 317 SUPERFAMILY SSF100950 67 316 1.88E-58 T 10-03-2017 RG49_RS25115 115d5a4081836103ad363b4a5bd0f9dd 16 Pfam PF08047 Histidine operon leader peptide 1 16 4.4E-10 T 10-03-2017 IPR012565 Histidine operon leader peptide GO:0000105 RG49_RS07230 388b7440f751b01deb0d56ef744bb678 49 Hamap MF_01484 Multidrug efflux pump accessory protein AcrZ [acrZ]. 1 46 19.084 T 10-03-2017 IPR019702 Multidrug efflux pump accessory protein AcrZ GO:0005886|GO:0006855|GO:0015238 RG49_RS07230 388b7440f751b01deb0d56ef744bb678 49 Pfam PF10766 Multidrug efflux pump-associated protein AcrZ 1 45 6.9E-29 T 10-03-2017 IPR019702 Multidrug efflux pump accessory protein AcrZ GO:0005886|GO:0006855|GO:0015238 RG49_RS06205 8b942c35860846a30392f6a1560ac9f7 230 Gene3D G3DSA:3.30.240.20 95 167 1.4E-23 T 10-03-2017 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain RG49_RS06205 8b942c35860846a30392f6a1560ac9f7 230 Pfam PF04239 Protein of unknown function (DUF421) 104 170 1.2E-15 T 10-03-2017 IPR007353 Protein of unknown function DUF421 RG49_RS03260 a384d69a287af333f96db37ea865f71f 197 TIGRFAM TIGR00477 tehB: tellurite resistance protein TehB 1 196 4.4E-113 T 10-03-2017 IPR004537 Tellurite resistance methyltransferase, TehB GO:0005737|GO:0008757|GO:0046690 RG49_RS03260 a384d69a287af333f96db37ea865f71f 197 Pfam PF03848 Tellurite resistance protein TehB 1 193 9.6E-110 T 10-03-2017 IPR015985 Tellurite resistance methyltransferase TehB-like domain RG49_RS03260 a384d69a287af333f96db37ea865f71f 197 SUPERFAMILY SSF53335 7 196 2.01E-33 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS03260 a384d69a287af333f96db37ea865f71f 197 Gene3D G3DSA:3.40.50.150 7 196 1.4E-38 T 10-03-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase RG49_RS03500 a742fedb3e02d0abb3da07ddc4d939db 140 Pfam PF03724 META domain 28 131 3.5E-23 T 10-03-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ RG49_RS10050 d4305ead99bde46e552599a506bd71f7 165 Pfam PF06146 Phosphate-starvation-inducible E 73 141 1.2E-15 T 10-03-2017 IPR020948 Phosphate-starvation-induced PsiE-like RG49_RS23440 2115501e2a116e8ff68efd8802eec3f9 269 Pfam PF01925 Sulfite exporter TauE/SafE 18 253 2.0E-42 T 10-03-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 RG49_RS00310 ccfb4a7497fbd98dafee3c38a9c78618 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 2.7E-34 T 10-03-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 RG49_RS00310 ccfb4a7497fbd98dafee3c38a9c78618 222 Gene3D G3DSA:1.10.3720.10 12 216 2.5E-56 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS00310 ccfb4a7497fbd98dafee3c38a9c78618 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 2.8E-25 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS00310 ccfb4a7497fbd98dafee3c38a9c78618 222 SUPERFAMILY SSF161098 13 203 1.31E-52 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS08760 bc54172278741905cd4b02571125d3ec 125 Pfam PF04304 Protein of unknown function (DUF454) 3 116 4.3E-41 T 10-03-2017 IPR007401 Protein of unknown function DUF454 RG49_RS08760 bc54172278741905cd4b02571125d3ec 125 PIRSF PIRSF016789 2 123 5.3E-51 T 10-03-2017 IPR007401 Protein of unknown function DUF454 RG49_RS09915 751787cd584546e973fc51dc472cdf67 310 SUPERFAMILY SSF82282 7 308 8.89E-86 T 10-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 RG49_RS09915 751787cd584546e973fc51dc472cdf67 310 Gene3D G3DSA:3.20.20.330 2 308 2.8E-97 T 10-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 RG49_RS09915 751787cd584546e973fc51dc472cdf67 310 Pfam PF02574 Homocysteine S-methyltransferase 17 308 1.1E-75 T 10-03-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 RG49_RS21080 d402373386ab2ea6d2299546ab240c2f 181 Hamap MF_01104 Protein Syd [syd]. 3 181 35.928 T 10-03-2017 IPR009948 Syd GO:0009898 RG49_RS21080 d402373386ab2ea6d2299546ab240c2f 181 Pfam PF07348 Syd protein (SUKH-2) 7 179 1.7E-72 T 10-03-2017 IPR009948 Syd GO:0009898 RG49_RS08765 009f52003504589085c9d5e7c8b34d37 175 Pfam PF07445 Primosomal replication protein priC 9 173 1.0E-45 T 10-03-2017 IPR010890 Primosomal replication PriB/PriC RG49_RS22595 3cc753bd76f724a3a9fe163c6876a182 681 Gene3D G3DSA:3.40.50.300 246 394 8.1E-7 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22595 3cc753bd76f724a3a9fe163c6876a182 681 Gene3D G3DSA:3.40.50.300 26 202 1.1E-11 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22595 3cc753bd76f724a3a9fe163c6876a182 681 SUPERFAMILY SSF52540 40 201 1.28E-22 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22595 3cc753bd76f724a3a9fe163c6876a182 681 SUPERFAMILY SSF52540 308 388 1.28E-22 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS22595 3cc753bd76f724a3a9fe163c6876a182 681 SUPERFAMILY SSF52540 229 279 1.28E-22 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS07900 a7c6de8d29fbfe9d0f23a1c6e706d9ac 193 Gene3D G3DSA:3.30.160.150 19 171 1.3E-58 T 10-03-2017 RG49_RS07900 a7c6de8d29fbfe9d0f23a1c6e706d9ac 193 Pfam PF04390 Lipopolysaccharide-assembly 11 159 3.9E-22 T 10-03-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 RG49_RS07900 a7c6de8d29fbfe9d0f23a1c6e706d9ac 193 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 4 164 26.045 T 10-03-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 RG49_RS02930 c2d2eec3f1fda1f562f4e4bd17649b15 71 Pfam PF10684 Putative biofilm-dependent modulation protein 1 71 2.2E-52 T 10-03-2017 IPR019625 Biofilm-dependent modulation protein Bdm, putative RG49_RS21100 956b20f3c8b78b296ce403ba1d6441c6 149 Pfam PF00258 Flavodoxin 6 140 2.4E-24 T 10-03-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 RG49_RS21100 956b20f3c8b78b296ce403ba1d6441c6 149 SUPERFAMILY SSF52218 1 148 2.42E-38 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS21100 956b20f3c8b78b296ce403ba1d6441c6 149 PRINTS PR00369 Flavodoxin signature 53 64 2.2E-6 T 10-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 RG49_RS21100 956b20f3c8b78b296ce403ba1d6441c6 149 PRINTS PR00369 Flavodoxin signature 108 127 2.2E-6 T 10-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 RG49_RS21100 956b20f3c8b78b296ce403ba1d6441c6 149 PRINTS PR00369 Flavodoxin signature 84 94 2.2E-6 T 10-03-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 RG49_RS21100 956b20f3c8b78b296ce403ba1d6441c6 149 Gene3D G3DSA:3.40.50.360 1 147 2.0E-34 T 10-03-2017 IPR029039 Flavoprotein-like domain RG49_RS18660 451703c97611612e1cca3fb94f78bc98 325 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 312 1.4E-106 T 10-03-2017 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 RG49_RS18660 451703c97611612e1cca3fb94f78bc98 325 Pfam PF01699 Sodium/calcium exchanger protein 4 143 5.4E-28 T 10-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 RG49_RS18660 451703c97611612e1cca3fb94f78bc98 325 Pfam PF01699 Sodium/calcium exchanger protein 175 317 2.4E-26 T 10-03-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 RG49_RS02365 f104b1a8704198942ae5c8a4421817c5 57 Pfam PF08178 GnsA/GnsB toxin of bacterial toxin-antitoxin system 1 54 1.5E-33 T 10-03-2017 IPR012563 Gns RG49_RS00140 72e2520f273898f23d559569705062d9 75 Pfam PF10733 Protein of unknown function (DUF2525) 18 75 2.3E-33 T 10-03-2017 IPR019669 Uncharacterised bacterial stress protein YodD RG49_RS13810 2192ebdf64a4b7a33c09b5d4791fec64 459 TIGRFAM TIGR00797 matE: MATE efflux family protein 35 428 1.2E-103 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS13810 2192ebdf64a4b7a33c09b5d4791fec64 459 Pfam PF01554 MatE 259 412 1.3E-10 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS13810 2192ebdf64a4b7a33c09b5d4791fec64 459 Pfam PF01554 MatE 35 196 1.1E-33 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS10830 0ea44a49b70285717a7432533a30b5a1 134 Hamap MF_00976 Outer membrane lipoprotein RcsF [rcsF]. 1 133 36.266 T 10-03-2017 IPR030852 Outer membrane lipoprotein RcsF GO:0009279|GO:0035556 RG49_RS10830 0ea44a49b70285717a7432533a30b5a1 134 Pfam PF16358 RcsF lipoprotein 29 132 7.6E-50 T 10-03-2017 IPR030852 Outer membrane lipoprotein RcsF GO:0009279|GO:0035556 RG49_RS03380 55df56cc617a9df51eb0660952195c40 185 Pfam PF10971 Protein of unknown function (DUF2773) 105 185 1.3E-46 T 10-03-2017 IPR024497 Protein of unknown function DUF2773 RG49_RS03380 55df56cc617a9df51eb0660952195c40 185 ProDom PD029376 YDBD YKIA ECS0442 ECS2009 105 183 2.0E-38 T 10-03-2017 IPR024497 Protein of unknown function DUF2773 RG49_RS11270 5becda1ac59c6ff4b0fc38e2b6c13165 617 Pfam PF11737 Protein of unknown function (DUF3300) 75 333 1.3E-81 T 10-03-2017 IPR021728 Protein of unknown function DUF3300 RG49_RS11160 a115362cd65464a9242df2822a0f99bf 198 Gene3D G3DSA:2.60.40.1090 41 198 3.5E-7 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11160 a115362cd65464a9242df2822a0f99bf 198 Pfam PF00419 Fimbrial protein 36 197 8.1E-7 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS11160 a115362cd65464a9242df2822a0f99bf 198 SUPERFAMILY SSF49401 31 198 8.95E-10 T 10-03-2017 IPR008966 Adhesion domain RG49_RS06135 ef2b934bf0fc95b31331d3429865cba6 259 Pfam PF02698 DUF218 domain 80 213 1.7E-27 T 10-03-2017 IPR003848 Domain of unknown function DUF218 RG49_RS06135 ef2b934bf0fc95b31331d3429865cba6 259 Gene3D G3DSA:3.40.50.620 74 210 3.6E-17 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS14785 ea4300e7a06ce57b7ec0c32983e445e1 678 SUPERFAMILY SSF74650 13 225 9.1E-24 T 10-03-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 RG49_RS14785 ea4300e7a06ce57b7ec0c32983e445e1 678 SUPERFAMILY SSF51445 235 583 1.05E-51 T 10-03-2017 IPR017853 Glycoside hydrolase superfamily RG49_RS14785 ea4300e7a06ce57b7ec0c32983e445e1 678 Pfam PF01055 Glycosyl hydrolases family 31 230 665 6.6E-73 T 10-03-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 RG49_RS14785 ea4300e7a06ce57b7ec0c32983e445e1 678 SUPERFAMILY SSF51011 585 663 3.67E-21 T 10-03-2017 RG49_RS25025 0b221796486b4dee4f305d1eb320fe07 440 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 51 418 6.7E-12 T 10-03-2017 RG49_RS25025 0b221796486b4dee4f305d1eb320fe07 440 Pfam PF14296 O-antigen polysaccharide polymerase Wzy 4 422 1.3E-49 T 10-03-2017 IPR029468 O-antigen polysaccharide polymerase Wzy RG49_RS00745 59bf56dfa967d909e4e0b817bd08d2fa 290 Pfam PF05425 Copper resistance protein D 185 284 1.9E-24 T 10-03-2017 IPR008457 Copper resistance protein D GO:0016021 RG49_RS17785 aee8e5d8a562867c6ef59667b804c2ed 200 Gene3D G3DSA:1.10.3290.10 11 196 3.2E-54 T 10-03-2017 IPR003812 Fido domain RG49_RS17785 aee8e5d8a562867c6ef59667b804c2ed 200 Pfam PF02661 Fic/DOC family 58 152 2.4E-14 T 10-03-2017 IPR003812 Fido domain RG49_RS17785 aee8e5d8a562867c6ef59667b804c2ed 200 SUPERFAMILY SSF140931 41 195 1.44E-29 T 10-03-2017 IPR003812 Fido domain RG49_RS23495 21b21923ff6f1fa0d08ee0d7d60d1f78 219 Pfam PF09335 SNARE associated Golgi protein 49 176 5.6E-27 T 10-03-2017 IPR032816 SNARE associated Golgi protein RG49_RS01395 84ab58669017d6a598e21ffc93cc3041 252 Pfam PF04338 Protein of unknown function, DUF481 48 251 1.9E-55 T 10-03-2017 IPR007433 Protein of unknown function DUF481 RG49_RS03480 e17b93cceda521326f1ff88abfa8ce51 108 PIRSF PIRSF025560 1 107 3.4E-44 T 10-03-2017 IPR008309 Uncharacterised conserved protein UCP025560 RG49_RS03480 e17b93cceda521326f1ff88abfa8ce51 108 Pfam PF07027 Protein of unknown function (DUF1318) 18 107 4.5E-31 T 10-03-2017 IPR008309 Uncharacterised conserved protein UCP025560 RG49_RS17350 32dda504b11ad96e8f1f2b64f9169ddd 94 Pfam PF15567 Immunity protein 35 5 83 9.9E-22 T 10-03-2017 IPR029082 Immunity protein 35 RG49_RS23260 091c2d0c6fb2a0b381797e22f2b05b47 80 ProDom PD857460 MEMBRANE YFDY INNER TRANSMEMBRANE STY2638 ECS3257 1 80 7.0E-39 T 10-03-2017 IPR024470 Protein of unknown function DUF2545 RG49_RS23260 091c2d0c6fb2a0b381797e22f2b05b47 80 Pfam PF10810 Protein of unknown function (DUF2545) 1 80 1.9E-44 T 10-03-2017 IPR024470 Protein of unknown function DUF2545 RG49_RS24820 26a5164b46d0cc31bfa5592d1562efa2 253 Pfam PF13672 Protein phosphatase 2C 11 220 7.2E-41 T 10-03-2017 RG49_RS24820 26a5164b46d0cc31bfa5592d1562efa2 253 SUPERFAMILY SSF81606 10 188 2.62E-7 T 10-03-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 RG49_RS03720 fa243047619d08779918c7e851d3b226 51 ProDom PD019047 YDFA YDAF PROPHAGE ECS2210 ECS2767 ECS1505 STY2067 1 48 7.0E-23 T 10-03-2017 IPR009821 Protein of unknown function DUF1391 RG49_RS03720 fa243047619d08779918c7e851d3b226 51 Pfam PF07151 Protein of unknown function (DUF1391) 2 49 1.6E-36 T 10-03-2017 IPR009821 Protein of unknown function DUF1391 RG49_RS09835 e3b60519136a1d1b507b2df84c64014b 64 Gene3D G3DSA:1.10.10.10 14 60 7.8E-6 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS09835 e3b60519136a1d1b507b2df84c64014b 64 SUPERFAMILY SSF46785 1 55 4.41E-5 T 10-03-2017 IPR011991 Winged helix-turn-helix DNA-binding domain RG49_RS02660 1c3537c8dc669bc5d20831ec460dfe43 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 301 4.9E-44 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS10030 5bd0e0424515a0090208331b3d76a981 203 Pfam PF03729 Short repeat of unknown function (DUF308) 30 101 4.0E-13 T 10-03-2017 IPR005325 Protein of unknown function DUF308, membrane RG49_RS10030 5bd0e0424515a0090208331b3d76a981 203 Pfam PF03729 Short repeat of unknown function (DUF308) 88 161 2.6E-9 T 10-03-2017 IPR005325 Protein of unknown function DUF308, membrane RG49_RS05785 99b0df83fcc4f5ebabeaa7093da7de4c 698 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 33 690 3.6E-266 T 10-03-2017 IPR010344 Exopolysaccharide biosynthesis protein YbjH RG49_RS21140 2d2ac8345144c9aa328a5b8b633fd297 111 SUPERFAMILY SSF50118 4 111 2.83E-33 T 10-03-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor RG49_RS21140 2d2ac8345144c9aa328a5b8b633fd297 111 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 10 109 2.3E-22 T 10-03-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 RG49_RS21140 2d2ac8345144c9aa328a5b8b633fd297 111 Gene3D G3DSA:2.30.30.110 4 110 1.2E-36 T 10-03-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor RG49_RS10675 97285d25a18104026765be8acc3e2226 253 Pfam PF09850 Type VI secretion system protein DotU 33 233 1.6E-54 T 10-03-2017 IPR017732 Type IV / VI secretion system, DotU RG49_RS10675 97285d25a18104026765be8acc3e2226 253 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 32 242 2.2E-64 T 10-03-2017 IPR017732 Type IV / VI secretion system, DotU RG49_RS05965 61acd3582d9c4b965d1feae2c5e4a5ff 546 Pfam PF02470 MlaD protein 158 217 7.2E-8 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS05965 61acd3582d9c4b965d1feae2c5e4a5ff 546 Pfam PF02470 MlaD protein 42 133 5.3E-9 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS05965 61acd3582d9c4b965d1feae2c5e4a5ff 546 Pfam PF02470 MlaD protein 285 389 1.2E-14 T 10-03-2017 IPR003399 Mce/MlaD RG49_RS15390 e9f588040b00f0a765a09edb29d4dc3c 112 Pfam PF04219 Protein of unknown function, DUF 10 98 2.7E-39 T 10-03-2017 IPR007335 Protein of unknown function DUF413 RG49_RS24540 8779934939f8d857811a6b91a06ced7e 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 238 2.9E-22 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24540 8779934939f8d857811a6b91a06ced7e 243 Gene3D G3DSA:1.10.3720.10 8 239 3.7E-30 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS24540 8779934939f8d857811a6b91a06ced7e 243 SUPERFAMILY SSF161098 46 233 1.15E-32 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS19560 57e0a11356ce3ca0dc086400937f1a7e 386 SUPERFAMILY SSF56059 1 168 1.94E-95 T 10-03-2017 RG49_RS19560 57e0a11356ce3ca0dc086400937f1a7e 386 SUPERFAMILY SSF56059 266 383 1.94E-95 T 10-03-2017 RG49_RS19560 57e0a11356ce3ca0dc086400937f1a7e 386 SUPERFAMILY SSF52440 174 279 3.16E-39 T 10-03-2017 IPR016185 Pre-ATP-grasp domain RG49_RS19560 57e0a11356ce3ca0dc086400937f1a7e 386 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 384 1.9E-162 T 10-03-2017 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain RG49_RS03990 99c0984e2324b15155000d53c88eb7e0 430 SUPERFAMILY SSF53850 21 427 5.98E-59 T 10-03-2017 RG49_RS03990 99c0984e2324b15155000d53c88eb7e0 430 Gene3D G3DSA:3.40.190.10 149 348 2.8E-42 T 10-03-2017 RG49_RS03990 99c0984e2324b15155000d53c88eb7e0 430 Pfam PF01547 Bacterial extracellular solute-binding protein 43 325 4.0E-38 T 10-03-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 RG49_RS01030 7712dd7f08af42f280e755248cd9f3ac 393 Pfam PF07690 Major Facilitator Superfamily 23 349 4.4E-18 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS01030 7712dd7f08af42f280e755248cd9f3ac 393 TIGRFAM TIGR00896 CynX: cyanate transporter 15 368 4.2E-151 T 10-03-2017 IPR004747 Cyanate transport system protein GO:0016021 RG49_RS01030 7712dd7f08af42f280e755248cd9f3ac 393 Gene3D G3DSA:1.20.1250.20 14 192 9.5E-16 T 10-03-2017 RG49_RS01030 7712dd7f08af42f280e755248cd9f3ac 393 Gene3D G3DSA:1.20.1250.20 207 388 5.2E-13 T 10-03-2017 RG49_RS01030 7712dd7f08af42f280e755248cd9f3ac 393 SUPERFAMILY SSF103473 7 389 1.24E-43 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS10515 c126a2de3452f05a689af37b57bb37eb 97 SUPERFAMILY SSF143120 9 56 3.01E-6 T 10-03-2017 RG49_RS10515 c126a2de3452f05a689af37b57bb37eb 97 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 52 2.0E-6 T 10-03-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM RG49_RS24575 16dee4badeed3bf3f5636bb7c0749ba7 666 Pfam PF04434 SWIM zinc finger 64 88 0.011 T 10-03-2017 IPR007527 Zinc finger, SWIM-type GO:0008270 RG49_RS24575 16dee4badeed3bf3f5636bb7c0749ba7 666 Pfam PF04434 SWIM zinc finger 159 183 0.082 T 10-03-2017 IPR007527 Zinc finger, SWIM-type GO:0008270 RG49_RS02420 a39a262af8566a4670aafa5c5ffb246f 133 SUPERFAMILY SSF143749 3 132 6.54E-50 T 10-03-2017 IPR009312 Minor tail protein U-like RG49_RS02420 a39a262af8566a4670aafa5c5ffb246f 133 Pfam PF06141 Phage minor tail protein U 3 131 9.4E-48 T 10-03-2017 IPR009312 Minor tail protein U-like RG49_RS01000 455f98bebfeb521aa6aa9acd749a3b4e 82 Pfam PF04226 Transglycosylase associated protein 33 81 4.7E-17 T 10-03-2017 IPR007341 Transglycosylase-associated protein GO:0016021 RG49_RS02380 a077337e3d230fae639f42d20eb7a0cb 164 Pfam PF07278 Protein of unknown function (DUF1441) 10 151 7.7E-48 T 10-03-2017 IPR009901 Bacteriophage VT1-Sakai, H0025 RG49_RS02415 1f30d81c00f76036c776909586c216ff 192 Pfam PF06763 Prophage minor tail protein Z (GPZ) 1 192 1.6E-74 T 10-03-2017 IPR010633 Bacteriophage lambda, GpZ, minor tail RG49_RS02415 1f30d81c00f76036c776909586c216ff 192 PIRSF PIRSF004395 1 192 1.9E-88 T 10-03-2017 IPR010633 Bacteriophage lambda, GpZ, minor tail RG49_RS02780 ccc574f8ece94d83b46f9023c9d221b7 85 Gene3D G3DSA:2.10.230.10 4 63 3.3E-8 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS02780 ccc574f8ece94d83b46f9023c9d221b7 85 SUPERFAMILY SSF57938 3 62 4.05E-8 T 10-03-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 RG49_RS07650 9ee1548ee0a7b45fa48b2a9100a3594f 252 Pfam PF10946 Protein of unknown function DUF2625 40 238 1.9E-86 T 10-03-2017 IPR021239 Protein of unknown function DUF2625 RG49_RS03980 0946be28916cee1935cc76c354455acd 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 267 2.6E-17 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03980 0946be28916cee1935cc76c354455acd 280 Gene3D G3DSA:1.10.3720.10 4 266 4.6E-67 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS03980 0946be28916cee1935cc76c354455acd 280 SUPERFAMILY SSF161098 5 280 5.76E-71 T 10-03-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 RG49_RS08590 4cad79037f47d23a61b9af142ed8b851 804 Pfam PF02687 FtsX-like permease family 247 364 6.8E-10 T 10-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 RG49_RS08590 4cad79037f47d23a61b9af142ed8b851 804 Pfam PF02687 FtsX-like permease family 683 791 5.0E-12 T 10-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 RG49_RS10245 458463b7e455f7e588c8414478f93320 89 Pfam PF10109 Phage tail assembly chaperone proteins, E, or 41 or 14 4 86 1.2E-14 T 10-03-2017 IPR019289 Bacteriophage tail protein Gp41, putative RG49_RS09160 cac643010e273e86918ad3bb0a83df4c 303 Pfam PF04381 Putative exonuclease, RdgC 2 300 2.2E-129 T 10-03-2017 IPR007476 Putative exonuclease, RdgC GO:0006310 RG49_RS09160 cac643010e273e86918ad3bb0a83df4c 303 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 2 302 44.467 T 10-03-2017 IPR007476 Putative exonuclease, RdgC GO:0006310 RG49_RS10845 7e940c308e3407f48fba841d8c920aca 274 Gene3D G3DSA:2.30.30.330 63 237 2.0E-25 T 10-03-2017 RG49_RS10845 7e940c308e3407f48fba841d8c920aca 274 SUPERFAMILY SSF54001 64 160 2.49E-29 T 10-03-2017 RG49_RS10845 7e940c308e3407f48fba841d8c920aca 274 SUPERFAMILY SSF54001 201 264 2.49E-29 T 10-03-2017 RG49_RS10845 7e940c308e3407f48fba841d8c920aca 274 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 65 156 1.7E-9 T 10-03-2017 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family RG49_RS12990 e2e92e80c43ebeee5882b4149b8976f0 212 Pfam PF06693 Protein of unknown function (DUF1190) 67 211 3.8E-20 T 10-03-2017 IPR009576 Biofilm formation YgiB RG49_RS07295 1c41427b681785fd1d7be801c76228b7 347 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 22 341 6.3E-131 T 10-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 RG49_RS07295 1c41427b681785fd1d7be801c76228b7 347 SUPERFAMILY SSF142754 29 341 4.97E-108 T 10-03-2017 RG49_RS07295 1c41427b681785fd1d7be801c76228b7 347 Pfam PF02445 Quinolinate synthetase A protein 31 340 1.2E-103 T 10-03-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 RG49_RS07295 1c41427b681785fd1d7be801c76228b7 347 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 347 72.329 T 10-03-2017 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 RG49_RS23190 46b03e93eba98dbcb2c9463dcc4d52a9 108 Pfam PF10697 Protein of unknown function (DUF2502) 23 106 2.1E-19 T 10-03-2017 IPR019638 Protein of unknown function DUF2502 RG49_RS19515 81225be9a54653003656bd9e22a4d586 354 SUPERFAMILY SSF49401 219 354 1.18E-7 T 10-03-2017 IPR008966 Adhesion domain RG49_RS19515 81225be9a54653003656bd9e22a4d586 354 Pfam PF00419 Fimbrial protein 226 353 1.4E-6 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS19515 81225be9a54653003656bd9e22a4d586 354 Gene3D G3DSA:2.60.40.1090 223 354 2.0E-4 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS22645 3e687d05b19d5cd4a374f92003ff6a79 212 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 191 1.0E-84 T 10-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 RG49_RS22645 3e687d05b19d5cd4a374f92003ff6a79 212 SUPERFAMILY SSF53328 1 205 3.53E-66 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS22645 3e687d05b19d5cd4a374f92003ff6a79 212 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 187 31.676 T 10-03-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 RG49_RS22645 3e687d05b19d5cd4a374f92003ff6a79 212 Pfam PF00551 Formyl transferase 1 181 6.9E-68 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS22645 3e687d05b19d5cd4a374f92003ff6a79 212 Gene3D G3DSA:3.40.50.170 1 199 7.8E-71 T 10-03-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS22645 3e687d05b19d5cd4a374f92003ff6a79 212 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 10-03-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 RG49_RS12320 9218c0ccc00e319ca02a3c60513f501b 255 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 247 4.0E-69 T 10-03-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 RG49_RS12320 9218c0ccc00e319ca02a3c60513f501b 255 SUPERFAMILY SSF53067 3 246 3.25E-32 T 10-03-2017 RG49_RS12320 9218c0ccc00e319ca02a3c60513f501b 255 Gene3D G3DSA:3.30.420.40 92 230 8.8E-46 T 10-03-2017 RG49_RS12320 9218c0ccc00e319ca02a3c60513f501b 255 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 247 1.8E-109 T 10-03-2017 IPR008275 CoA enzyme activase RG49_RS11210 b33785388ed7fee27027fd1c6f05e055 256 PIRSF PIRSF006648 11 252 4.4E-22 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS11210 b33785388ed7fee27027fd1c6f05e055 256 Pfam PF01061 ABC-2 type transporter 9 218 2.6E-39 T 10-03-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 RG49_RS11210 b33785388ed7fee27027fd1c6f05e055 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 58 80 1.9E-7 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS11210 b33785388ed7fee27027fd1c6f05e055 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 1.9E-7 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS11210 b33785388ed7fee27027fd1c6f05e055 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 139 163 1.9E-7 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS11210 b33785388ed7fee27027fd1c6f05e055 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 1.9E-7 T 10-03-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 RG49_RS22960 9d8113afcfd6bd799d0b102affd72088 149 Pfam PF11143 Protein of unknown function (DUF2919) 6 145 2.1E-48 T 10-03-2017 IPR021318 Protein of unknown function DUF2919 RG49_RS05540 12a4573647d2d3387ea14c7535f47b96 107 SUPERFAMILY SSF52151 1 85 2.88E-12 T 10-03-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 RG49_RS05540 12a4573647d2d3387ea14c7535f47b96 107 Gene3D G3DSA:3.40.366.10 1 93 1.8E-10 T 10-03-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 RG49_RS23865 f25145af9893429c4dfaa5c6a7483aa4 429 Gene3D G3DSA:1.20.1250.20 231 416 3.1E-15 T 10-03-2017 RG49_RS23865 f25145af9893429c4dfaa5c6a7483aa4 429 SUPERFAMILY SSF103473 9 417 2.49E-72 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS23865 f25145af9893429c4dfaa5c6a7483aa4 429 Pfam PF07690 Major Facilitator Superfamily 23 381 5.8E-45 T 10-03-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 RG49_RS23865 f25145af9893429c4dfaa5c6a7483aa4 429 Gene3D G3DSA:1.20.1250.20 14 212 2.9E-40 T 10-03-2017 RG49_RS23985 8052f4b1a1591eb979f9030fc61c1eff 258 PIRSF PIRSF012281 1 258 2.9E-128 T 10-03-2017 IPR012039 Uncharacterised conserved protein UCP012281 RG49_RS23985 8052f4b1a1591eb979f9030fc61c1eff 258 Pfam PF09906 Uncharacterized protein conserved in bacteria (DUF2135) 199 244 1.4E-18 T 10-03-2017 IPR019220 Domain of unknown function DUF2135 RG49_RS06770 0a334681f7dbd77c0810d046eab3e01d 350 Gene3D G3DSA:1.10.443.10 170 328 1.6E-35 T 10-03-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS06770 0a334681f7dbd77c0810d046eab3e01d 350 Pfam PF00589 Phage integrase family 174 246 1.0E-9 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS06770 0a334681f7dbd77c0810d046eab3e01d 350 Pfam PF00589 Phage integrase family 280 320 5.4E-11 T 10-03-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 RG49_RS06770 0a334681f7dbd77c0810d046eab3e01d 350 SUPERFAMILY SSF56349 60 326 7.3E-43 T 10-03-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 RG49_RS23815 00eab6701f3f824f58a08890feb2529e 296 Gene3D G3DSA:3.20.20.370 82 268 6.4E-27 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS23815 00eab6701f3f824f58a08890feb2529e 296 Gene3D G3DSA:3.20.20.370 13 38 6.4E-27 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS23815 00eab6701f3f824f58a08890feb2529e 296 Pfam PF01522 Polysaccharide deacetylase 15 167 6.6E-13 T 10-03-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 RG49_RS23815 00eab6701f3f824f58a08890feb2529e 296 Hamap MF_01870 Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD [arnD]. 1 292 61.733 T 10-03-2017 IPR023557 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD, probable GO:0016811 RG49_RS23815 00eab6701f3f824f58a08890feb2529e 296 SUPERFAMILY SSF88713 85 267 3.06E-27 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS23815 00eab6701f3f824f58a08890feb2529e 296 SUPERFAMILY SSF88713 14 41 3.06E-27 T 10-03-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 RG49_RS19785 cd9f5956f94fc8cb7105b18e978d56f7 392 Pfam PF03916 Polysulphide reductase, NrfD 45 330 1.8E-18 T 10-03-2017 IPR005614 NrfD family RG49_RS21450 0767ce54ee39b8e281fcbd854dae8cc2 153 Pfam PF11046 Transcriptional repressor of hyc and hyp operons 1 145 1.2E-75 T 10-03-2017 IPR021285 Transcription regulator, HycA RG49_RS21730 88dafdd2f1e6b9926ee59fd6763d3056 109 Pfam PF05957 Bacterial protein of unknown function (DUF883) 16 107 6.4E-26 T 10-03-2017 IPR010279 Protein of unknown function DUF883, ElaB RG49_RS05060 e9efcd3a80a658300659ce3eee5d4220 357 Pfam PF01757 Acyltransferase family 7 326 8.2E-23 T 10-03-2017 IPR002656 Acyltransferase 3 GO:0016747 RG49_RS24620 514eb4d6bbe43a7c253e4501aa7a81ad 93 Pfam PF10836 Protein of unknown function (DUF2574) 1 93 1.2E-52 T 10-03-2017 IPR020386 Uncharacterised protein family YehE RG49_RS24620 514eb4d6bbe43a7c253e4501aa7a81ad 93 ProDom PD064930 YEHE MEMBRANE OUTER STY2382 PRECURSOR ECS2918 SIGNAL 1 83 3.0E-44 T 10-03-2017 IPR020386 Uncharacterised protein family YehE RG49_RS12125 61c27c1430528e71237fa44e3aa2e192 157 Pfam PF12821 Threonine/Serine exporter, ThrE 13 147 3.5E-33 T 10-03-2017 IPR024528 Threonine/Serine exporter, ThrE RG49_RS12125 61c27c1430528e71237fa44e3aa2e192 157 Hamap MF_01191 UPF0442 protein YjjB [yjjB]. 1 157 46.186 T 10-03-2017 IPR020914 Uncharacterised protein family UPF0442 RG49_RS00575 ae4ae0fa31f2635e6c6508ff81b9d94f 272 Gene3D G3DSA:3.20.20.410 1 261 4.2E-73 T 10-03-2017 IPR002763 Protein of unknown function DUF72 RG49_RS00575 ae4ae0fa31f2635e6c6508ff81b9d94f 272 Pfam PF01904 Protein of unknown function DUF72 21 248 1.3E-51 T 10-03-2017 IPR002763 Protein of unknown function DUF72 RG49_RS00575 ae4ae0fa31f2635e6c6508ff81b9d94f 272 SUPERFAMILY SSF117396 1 253 2.62E-65 T 10-03-2017 IPR002763 Protein of unknown function DUF72 RG49_RS04215 00ed2acece391bc2d4fba1e81e860271 83 Pfam PF10692 Protein of unknown function (DUF2498) 4 81 1.2E-42 T 10-03-2017 IPR019633 Protein of unknown function DUF2498 RG49_RS00115 8d0fb76c06618313bbf75b0dbf5c17ae 305 PIRSF PIRSF016660 3 305 1.9E-125 T 10-03-2017 IPR008526 Inner membrane protein YedI RG49_RS00115 8d0fb76c06618313bbf75b0dbf5c17ae 305 Pfam PF05661 Protein of unknown function (DUF808) 6 291 1.3E-113 T 10-03-2017 IPR008526 Inner membrane protein YedI RG49_RS18625 261ff6da90a7a3f692be0c00dde3dae7 95 Gene3D G3DSA:3.30.160.100 1 95 3.7E-37 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS18625 261ff6da90a7a3f692be0c00dde3dae7 95 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 1.9E-37 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS18625 261ff6da90a7a3f692be0c00dde3dae7 95 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 3.7E-27 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS18625 261ff6da90a7a3f692be0c00dde3dae7 95 SUPERFAMILY SSF69754 1 95 8.11E-33 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS09190 76276175b24bc2a79c2eb244dd5c3de7 63 Pfam PF16362 YaiA protein 1 63 7.7E-40 T 10-03-2017 IPR032303 YaiA protein RG49_RS17080 5c3e9984919757f7cc69deb288ba224a 144 Gene3D G3DSA:3.40.50.620 3 139 7.3E-32 T 10-03-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold RG49_RS17080 5c3e9984919757f7cc69deb288ba224a 144 PIRSF PIRSF006276 1 141 3.4E-54 T 10-03-2017 IPR006015 Universal stress protein A RG49_RS17080 5c3e9984919757f7cc69deb288ba224a 144 SUPERFAMILY SSF52402 3 139 1.59E-32 T 10-03-2017 RG49_RS17080 5c3e9984919757f7cc69deb288ba224a 144 Pfam PF00582 Universal stress protein family 3 138 2.4E-21 T 10-03-2017 IPR006016 UspA GO:0006950 RG49_RS13350 3d34b2e2e8ab03f69004b3b594c071f1 469 Pfam PF13347 MFS/sugar transport protein 6 432 8.6E-87 T 10-03-2017 RG49_RS13350 3d34b2e2e8ab03f69004b3b594c071f1 469 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 55 80 - T 10-03-2017 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 RG49_RS13350 3d34b2e2e8ab03f69004b3b594c071f1 469 Gene3D G3DSA:1.20.1250.20 9 195 6.8E-13 T 10-03-2017 RG49_RS13350 3d34b2e2e8ab03f69004b3b594c071f1 469 Gene3D G3DSA:1.20.1250.20 226 424 5.6E-6 T 10-03-2017 RG49_RS13350 3d34b2e2e8ab03f69004b3b594c071f1 469 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 4 446 5.4E-174 T 10-03-2017 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 RG49_RS13350 3d34b2e2e8ab03f69004b3b594c071f1 469 SUPERFAMILY SSF103473 6 438 6.93E-31 T 10-03-2017 IPR020846 Major facilitator superfamily domain RG49_RS05395 d9e18784e818e532bdf30ea5ef71f2fa 124 Pfam PF13984 MsyB protein 3 124 3.0E-64 T 10-03-2017 IPR025729 MsyB protein RG49_RS11515 abfa044baa298f169ea62ac6b48e1185 43 Pfam PF15894 Inhibitor of glucose uptake transporter SgrT 3 37 5.7E-11 T 10-03-2017 IPR031767 Inhibitor of glucose uptake transporter SgrT GO:0046325 RG49_RS10300 976da537220a129b142d8aa3e90c6eba 413 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 39 379 5.0E-78 T 10-03-2017 IPR006427 Phage portal protein, HK97 RG49_RS10300 976da537220a129b142d8aa3e90c6eba 413 Pfam PF04860 Phage portal protein 47 373 1.0E-99 T 10-03-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein RG49_RS24525 d572aa6ab6a64fad9282a20959414f10 305 SUPERFAMILY SSF53850 26 303 7.06E-59 T 10-03-2017 RG49_RS24525 d572aa6ab6a64fad9282a20959414f10 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 300 2.5E-60 T 10-03-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 RG49_RS24525 d572aa6ab6a64fad9282a20959414f10 305 Gene3D G3DSA:3.40.190.10 24 133 1.1E-55 T 10-03-2017 RG49_RS24525 d572aa6ab6a64fad9282a20959414f10 305 Gene3D G3DSA:3.40.190.10 254 304 1.1E-55 T 10-03-2017 RG49_RS24525 d572aa6ab6a64fad9282a20959414f10 305 Gene3D G3DSA:3.40.190.120 134 241 1.2E-27 T 10-03-2017 RG49_RS05270 6f45e827bcc45f6298b451d1cef08755 231 Pfam PF13861 FlgD Tudor-like domain 87 228 1.9E-16 T 10-03-2017 IPR025963 FlgD Tudor-like domain RG49_RS05270 6f45e827bcc45f6298b451d1cef08755 231 Pfam PF03963 Flagellar hook capping protein - N-terminal region 11 79 7.0E-25 T 10-03-2017 IPR005648 Flagellar hook capping protein RG49_RS05270 6f45e827bcc45f6298b451d1cef08755 231 Pfam PF13860 FlgD Ig-like domain 119 189 2.0E-23 T 10-03-2017 IPR025965 FlgD Ig-like domain RG49_RS08800 59f4d82cd10395502e6959ccb0935bc9 124 Pfam PF10757 Biofilm formation regulator YbaJ 1 117 5.5E-62 T 10-03-2017 IPR019693 Biofilm formation regulator YbaJ RG49_RS21465 d18a0adcc8778222e60fbaa4b6288423 608 Pfam PF00361 Proton-conducting membrane transporter 124 404 2.3E-38 T 10-03-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21465 d18a0adcc8778222e60fbaa4b6288423 608 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 154 178 7.8E-7 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21465 d18a0adcc8778222e60fbaa4b6288423 608 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 373 399 7.8E-7 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS21465 d18a0adcc8778222e60fbaa4b6288423 608 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 321 340 7.8E-7 T 10-03-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS06720 ccdea6649b92720a99177d6c96eb4c49 804 ProDom PD092055 ENDONUCLEASE POSSIBLE PROPHAGE FOR ORFE TRANSPOSABLE FELS-2 RETRON STY4635 ELEMENT 656 801 4.0E-70 T 10-03-2017 IPR020220 Retron, EC67, C-terminal GO:0016788 RG49_RS06720 ccdea6649b92720a99177d6c96eb4c49 804 Pfam PF05840 Bacteriophage replication gene A protein (GPA) 188 562 1.6E-145 T 10-03-2017 IPR008766 Replication gene A protein GO:0006260 RG49_RS19280 e11ec548a79753999e550101197c400f 167 Pfam PF01863 Protein of unknown function DUF45 95 149 3.2E-10 T 10-03-2017 IPR002725 Protein of unknown function DUF45 RG49_RS00265 afe2c35082432cc86cbbe2a7e19876c1 121 Gene3D G3DSA:1.20.58.380 8 93 2.9E-18 T 10-03-2017 RG49_RS00265 afe2c35082432cc86cbbe2a7e19876c1 121 Pfam PF05400 Flagellar protein FliT 21 106 7.8E-20 T 10-03-2017 IPR008622 Flagellar protein FliT RG49_RS23715 2a56b67a8afad091f5da9e616f631735 282 Gene3D G3DSA:1.25.40.10 96 160 1.1E-6 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS23715 2a56b67a8afad091f5da9e616f631735 282 SUPERFAMILY SSF48452 96 160 1.11E-7 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS10335 abb8bf751e85800847bc7131a5d9cbb6 158 Gene3D G3DSA:1.10.530.10 2 156 2.6E-67 T 10-03-2017 RG49_RS10335 abb8bf751e85800847bc7131a5d9cbb6 158 SUPERFAMILY SSF53955 2 152 5.45E-54 T 10-03-2017 IPR023346 Lysozyme-like domain RG49_RS10335 abb8bf751e85800847bc7131a5d9cbb6 158 Pfam PF00959 Phage lysozyme 33 138 3.5E-22 T 10-03-2017 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 RG49_RS00025 8ef3c062510a6f44bad85ab31cfe59dd 216 Gene3D G3DSA:2.40.128.20 30 216 4.3E-88 T 10-03-2017 IPR012674 Calycin RG49_RS00025 8ef3c062510a6f44bad85ab31cfe59dd 216 SUPERFAMILY SSF50814 31 216 2.8E-80 T 10-03-2017 IPR011038 Calycin-like RG49_RS00025 8ef3c062510a6f44bad85ab31cfe59dd 216 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 37 216 1.6E-84 T 10-03-2017 IPR015304 ZinT domain GO:0008270 RG49_RS08480 39132e038edffe5909359bf4da732e2f 271 Pfam PF11392 Protein of unknown function (DUF2877) 159 263 1.7E-28 T 10-03-2017 IPR021530 Protein of unknown function DUF2877 RG49_RS21385 cedb3c352760e92db74444eddde90dcd 420 Pfam PF07005 Putative sugar-binding N-terminal domain 4 227 1.7E-69 T 10-03-2017 IPR010737 Putative sugar-binding, N-terminal domain RG49_RS21385 cedb3c352760e92db74444eddde90dcd 420 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 253 411 2.0E-40 T 10-03-2017 IPR031475 Putative nucleotide-binding C-terminal domain RG49_RS21385 cedb3c352760e92db74444eddde90dcd 420 SUPERFAMILY SSF142764 4 418 6.54E-130 T 10-03-2017 RG49_RS24810 341a7a2d8f5bf41e55ebf6666af0b702 19 Pfam PF13956 Toxin Ibs, type I toxin-antitoxin system 1 19 1.8E-12 T 10-03-2017 IPR025881 Toxin Ibs RG49_RS13665 f0ca57b7d8601f2a5ccdf27978c77e4d 104 Pfam PF04341 Protein of unknown function, DUF485 11 98 8.0E-33 T 10-03-2017 IPR007436 Protein of unknown function DUF485 RG49_RS11920 d95d12290aaa87a91f47d25299cfb6ce 157 PIRSF PIRSF003174 1 157 9.7E-70 T 10-03-2017 IPR010292 Uncharacterised protein family CreA RG49_RS11920 d95d12290aaa87a91f47d25299cfb6ce 157 Pfam PF05981 CreA protein 24 155 3.3E-58 T 10-03-2017 IPR010292 Uncharacterised protein family CreA RG49_RS17290 f3b3126d27a413d02b5c6fee54c114c0 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 6.6E-71 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS17140 1c91ed2264018ff0eebbbf36e224c475 374 Pfam PF12698 ABC-2 family transporter protein 26 363 1.9E-31 T 10-03-2017 RG49_RS03275 b554a1f054ecc3327c039a19e69dc033 179 Gene3D G3DSA:3.40.630.30 6 175 1.2E-45 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS03275 b554a1f054ecc3327c039a19e69dc033 179 Pfam PF13302 Acetyltransferase (GNAT) domain 11 150 1.0E-21 T 10-03-2017 IPR000182 GNAT domain GO:0008080 RG49_RS03275 b554a1f054ecc3327c039a19e69dc033 179 SUPERFAMILY SSF55729 7 175 3.78E-43 T 10-03-2017 IPR016181 Acyl-CoA N-acyltransferase RG49_RS01075 834628c6391cbb7c33fde8ac328b6104 248 Pfam PF06629 MltA-interacting protein MipA 28 248 3.5E-52 T 10-03-2017 IPR010583 MltA-interacting MipA RG49_RS11540 1efc011c87f10d10e62cbc9a04f61013 254 Pfam PF09335 SNARE associated Golgi protein 36 159 1.5E-18 T 10-03-2017 IPR032816 SNARE associated Golgi protein RG49_RS22015 0f1a1505a92b1343234682838ca09b1f 172 Pfam PF13689 Domain of unknown function (DUF4154) 34 167 1.5E-29 T 10-03-2017 IPR025293 Protein of unknown function DUF4154 RG49_RS20335 38a95d84901e00f2c24db98e397096fa 19 Pfam PF13956 Toxin Ibs, type I toxin-antitoxin system 1 19 5.4E-12 T 10-03-2017 IPR025881 Toxin Ibs RG49_RS08660 7598f3ba715f241145cd9f86a8208e80 50 Pfam PF12035 Protein of unknown function (DUF3521) 5 32 1.5E-7 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS19020 3b82fd43f53b87a7714a44c33bdddfb9 154 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 12 150 6.1E-55 T 10-03-2017 IPR021679 Toxin endonuclease, YhaV RG49_RS05465 81e30ecf38cdb07c6e8dcfc6d04c85a1 129 Pfam PF10627 Curli assembly protein CsgE 28 128 4.1E-33 T 10-03-2017 IPR018900 Curli assembly protein CsgE RG49_RS22610 4ce56e0e02f0797bcd47328dd3c75256 172 Pfam PF05433 Glycine zipper 2TM domain 73 114 7.3E-8 T 10-03-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 RG49_RS16835 e6e290341d850c93d35ca225f5dbd8b2 523 Pfam PF10995 GGDEF I-site like or GIL domain 165 474 1.1E-121 T 10-03-2017 IPR017745 Cellulose biosynthesis protein BcsE RG49_RS16835 e6e290341d850c93d35ca225f5dbd8b2 523 TIGRFAM TIGR03369 cellulose_bcsE: cellulose biosynthesis protein BcsE 161 475 1.3E-125 T 10-03-2017 IPR017745 Cellulose biosynthesis protein BcsE RG49_RS12705 75471cc3a3cf7853a49295d170331a14 31 Pfam PF12035 Protein of unknown function (DUF3521) 1 27 5.6E-7 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS13295 4ab13bfa7f38d4245489085048fe75b8 57 Pfam PF10753 Protein of unknown function (DUF2566) 4 57 2.1E-25 T 10-03-2017 IPR019689 Toxin GhoT/OrtT RG49_RS12380 2add831bf10ddd2dce82733805b2a010 276 Pfam PF10887 Protein of unknown function (DUF2686) 1 276 3.0E-150 T 10-03-2017 IPR021220 Protein of unknown function DUF2686 RG49_RS16920 3e1737b4d0fa1a6a841588f94205858e 337 PIRSF PIRSF035875 37 329 8.2E-24 T 10-03-2017 IPR017039 Virulence factor BrkB RG49_RS16920 3e1737b4d0fa1a6a841588f94205858e 337 Pfam PF03631 Virulence factor BrkB 66 325 6.0E-52 T 10-03-2017 IPR017039 Virulence factor BrkB RG49_RS16920 3e1737b4d0fa1a6a841588f94205858e 337 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 52 326 1.4E-136 T 10-03-2017 IPR005274 Inner membrane protein YhjD RG49_RS10380 b6646dd7fcf6a4234ea5165ce2524ddb 162 Pfam PF06069 PerC transcriptional activator 98 149 2.9E-8 T 10-03-2017 IPR024684 Transcriptional activator PerC/bacteriophage SfV Orf40 RG49_RS10380 b6646dd7fcf6a4234ea5165ce2524ddb 162 ProDom PD096295 YFDN SB43 ORF40 3 162 3.0E-83 T 10-03-2017 IPR020344 Bacteriophage SfV, Orf40 RG49_RS16660 b35b745ff72ec9fc3114a4af1c25c91f 113 Pfam PF05360 yiaA/B two helix domain 6 50 3.3E-8 T 10-03-2017 IPR008024 YiaAB two helix RG49_RS23745 92a8179018b6e47deb0a173691637af8 403 SUPERFAMILY SSF54001 165 329 1.35E-16 T 10-03-2017 RG49_RS23745 92a8179018b6e47deb0a173691637af8 403 Pfam PF02902 Ulp1 protease family, C-terminal catalytic domain 165 362 5.4E-33 T 10-03-2017 IPR003653 Ulp1 protease family, C-terminal catalytic domain GO:0006508|GO:0008234 RG49_RS08140 b9b84a95df18925b8dd5c34717a21dad 701 Pfam PF02554 Carbon starvation protein CstA 32 403 3.3E-168 T 10-03-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 RG49_RS08140 b9b84a95df18925b8dd5c34717a21dad 701 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 469 596 4.5E-35 T 10-03-2017 IPR025299 CstA, C-terminal domain RG49_RS16290 92583900408b902431a8b1e8cbc84e5f 419 Pfam PF04932 O-Antigen ligase 205 352 2.2E-9 T 10-03-2017 IPR007016 O-antigen ligase-related RG49_RS02195 3a6fb23c7b00cd63837f1aa3cdf59ee2 83 Pfam PF06806 Putative excisionase (DUF1233) 5 74 1.2E-34 T 10-03-2017 IPR009634 Bacteriophage 933W, Xis excisionase RG49_RS01610 a54604dcebb36d745995385bf2d3febb 89 Pfam PF15930 Domain of unknown function 28 89 9.7E-42 T 10-03-2017 IPR031830 Uncharacterised protein YdiH RG49_RS01990 afca01a8a5abfff6100aea5004d46e3f 502 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 480 2.5E-139 T 10-03-2017 IPR010352 Protein of unknown function DUF945 RG49_RS06240 e3df422ab6879a8f35675aa92ed46de7 476 Pfam PF13520 Amino acid permease 12 450 2.1E-29 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS06240 e3df422ab6879a8f35675aa92ed46de7 476 PIRSF PIRSF006060 1 474 1.1E-50 T 10-03-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 RG49_RS12480 032341da9f5719eb4669b023bcd17984 216 Pfam PF01844 HNH endonuclease 141 197 1.5E-5 T 10-03-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 RG49_RS22785 79de25710027b9941b278a537a881745 287 Pfam PF04228 Putative neutral zinc metallopeptidase 1 283 5.5E-143 T 10-03-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative RG49_RS20605 701bcd3cef398dbef67e59048f667ed2 209 Pfam PF13643 Domain of unknown function (DUF4145) 86 164 1.2E-16 T 10-03-2017 IPR025285 Domain of unknown function DUF4145 RG49_RS13980 2eb75f129de2147975e4af3a4e583821 524 Pfam PF07906 ShET2 enterotoxin, N-terminal region 117 379 1.6E-95 T 10-03-2017 IPR012927 ShET2 enterotoxin, N-terminal RG49_RS13005 1a57bb4e9510d192b7cfdbeb63f0fd04 232 Pfam PF04012 PspA/IM30 family 2 232 3.3E-57 T 10-03-2017 IPR007157 PspA/IM30 RG49_RS00750 641701ca2a971165e2b7e15b2a9cbea7 113 Pfam PF10709 Protein of unknown function (DUF2511) 26 113 3.4E-44 T 10-03-2017 IPR019648 Protein of unknown function DUF2511 RG49_RS16435 76ef4b0973c993f7f7c8a2ef5491fffa 120 PIRSF PIRSF028770 1 120 2.1E-67 T 10-03-2017 IPR011223 Uncharacterised conserved protein UCP028770 RG49_RS16435 76ef4b0973c993f7f7c8a2ef5491fffa 120 Pfam PF11742 Protein of unknown function (DUF3302) 3 78 1.6E-40 T 10-03-2017 IPR011223 Uncharacterised conserved protein UCP028770 RG49_RS06765 6fa5b8d72fb677e53ab87b5fd6ddbbbe 63 ProDom PD052090 YDCA PRECURSOR SIGNAL ECS2024 27 59 1.0E-9 T 10-03-2017 RG49_RS01840 b2a03d2e7fe3b375a54295440bd78a9a 155 Pfam PF05433 Glycine zipper 2TM domain 62 102 2.4E-7 T 10-03-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 RG49_RS20535 3451fe592e1eff2c83b98e5008c23c6d 59 Pfam PF12035 Protein of unknown function (DUF3521) 20 53 1.4E-16 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS25145 92cb828915d29f82603ef18fe677e383 352 Pfam PF04143 Sulphur transport 21 331 6.0E-102 T 10-03-2017 IPR007272 Sulphur transport domain RG49_RS10165 fb9ba232acd9053c77880cebb615bf69 177 Pfam PF06114 Domain of unknown function (DUF955) 89 168 5.1E-12 T 10-03-2017 IPR010359 HTH domain, IrrE-type RG49_RS02085 2755a4ed561345cffb3a6e23c4484e14 111 Hamap MF_00546 Acid shock protein [asr]. 10 111 16.598 T 10-03-2017 IPR023497 Acid shock protein RG49_RS06595 17404f9d058b6715e43cfae35fc41466 200 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 78 199 1.4E-25 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS06680 12aa5caac6a4de1fd1577a3261aac247 277 Pfam PF05929 Phage capsid scaffolding protein (GPO) serine peptidase 6 277 4.2E-117 T 10-03-2017 IPR009228 Capsid scaffolding protein GpO GO:0019069 RG49_RS16445 00a5e0d1afca1498744384a0e97aa721 145 Pfam PF15596 Immunity protein 57 1 109 2.3E-73 T 10-03-2017 IPR028955 Immunity protein 57 RG49_RS11860 53df78ce90872acb2f4c0752e5946a85 98 Pfam PF10697 Protein of unknown function (DUF2502) 25 72 3.2E-15 T 10-03-2017 IPR019638 Protein of unknown function DUF2502 RG49_RS09675 388ca9d51685c15a9a00ad80741d8503 111 Pfam PF04224 Protein of unknown function, DUF417 2 110 4.8E-44 T 10-03-2017 IPR007339 Protein of unknown function DUF417 RG49_RS18525 74b56db2445e0c37674e89bbc27bd4c6 375 Pfam PF06250 Protein of unknown function (DUF1016) 19 361 5.0E-106 T 10-03-2017 IPR009362 Protein of unknown function DUF1016 RG49_RS07600 f0406faac8b1ec3e482d3820d2abdc1d 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 5.7E-9 T 10-03-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 RG49_RS07600 f0406faac8b1ec3e482d3820d2abdc1d 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 29 2.3E-5 T 10-03-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 RG49_RS20095 dbfacff178fe3f821f92f5cf0121219a 238 Pfam PF11101 Protein of unknown function (DUF2884) 23 234 9.4E-41 T 10-03-2017 IPR021307 Protein of unknown function DUF2884 RG49_RS04895 c513878fbcbc7e2671afafffb0e66fe7 78 Pfam PF10798 Biofilm development protein YmgB/AriR 27 62 2.8E-5 T 10-03-2017 IPR024753 Regulatory protein AriR GO:0042710|GO:0071229 RG49_RS10305 61a3f6b49051fc15e327f4b15e1aed7b 60 ProDom PD052744 YMFR MEMBRANE TRANSMEMBRANE INTEGRAL SB3 GP3 25 57 6.0E-12 T 10-03-2017 IPR020297 Protein of unknown function YmfR RG49_RS01830 72ac7c40552321d2fa8aec410c3a37c1 78 Pfam PF07869 Protein of unknown function (DUF1656) 19 70 3.4E-14 T 10-03-2017 IPR012451 Protein of unknown function DUF1656 RG49_RS19725 5bdaec02fb5a7e801d2c81806ddbaf51 244 Pfam PF01618 MotA/TolQ/ExbB proton channel family 91 205 5.2E-35 T 10-03-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 RG49_RS19725 5bdaec02fb5a7e801d2c81806ddbaf51 244 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 11 222 9.1E-104 T 10-03-2017 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 RG49_RS22575 91868a52f3e689de8ee8170a28693401 264 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 16 263 1.9E-55 T 10-03-2017 IPR014147 Type IV conjugative transfer protein TrbJ RG49_RS22575 91868a52f3e689de8ee8170a28693401 264 SUPERFAMILY SSF101082 37 233 4.45E-35 T 10-03-2017 IPR023220 Type IV secretion system, VirB5-domain RG49_RS00190 06fc43f4d8fe0d35237de79ebe9ef69b 154 Pfam PF03748 Flagellar basal body-associated protein FliL 56 152 6.5E-20 T 10-03-2017 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 RG49_RS13740 831a5687da56a321a6ae8999dc605323 118 Pfam PF04237 YjbR 12 101 1.6E-18 T 10-03-2017 IPR007351 Uncharacterised protein YjbR RG49_RS13740 831a5687da56a321a6ae8999dc605323 118 SUPERFAMILY SSF142906 1 116 1.44E-35 T 10-03-2017 RG49_RS10390 4197e348dd30e57b8a89e92d840ba199 59 Pfam PF13973 Domain of unknown function (DUF4222) 2 53 2.4E-20 T 10-03-2017 IPR025317 Protein of unknown function DUF4222 RG49_RS00765 f09458ceeceecb70c53b22329e0f730f 63 Pfam PF07358 Protein of unknown function (DUF1482) 1 57 1.3E-35 T 10-03-2017 IPR009954 Protein of unknown function DUF1482 RG49_RS06365 0faa22a23ece1f6fc9ce2f4c176eb87f 330 Pfam PF04393 Protein of unknown function (DUF535) 48 325 6.9E-101 T 10-03-2017 IPR007488 Protein of unknown function DUF535 RG49_RS03645 14965542eaa021a8410889176dea14d8 96 Pfam PF07102 Protein of unknown function (DUF1364) 3 94 1.8E-42 T 10-03-2017 IPR010774 Protein of unknown function DUF1364 RG49_RS03645 14965542eaa021a8410889176dea14d8 96 Gene3D G3DSA:3.30.50.20 19 94 4.5E-41 T 10-03-2017 RG49_RS16465 cb7c6eb9ac0b71c31220de2518dfdd4f 153 Gene3D G3DSA:1.25.40.10 50 135 2.9E-10 T 10-03-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 RG49_RS16465 cb7c6eb9ac0b71c31220de2518dfdd4f 153 SUPERFAMILY SSF81901 49 133 7.32E-10 T 10-03-2017 RG49_RS16480 9dbc7bd0fdec3cc4d8a98b33d830b2cd 112 Pfam PF15606 Bacterial toxin 34 33 107 2.8E-44 T 10-03-2017 IPR028947 Bacterial toxin 34 RG49_RS11750 ba6191e60d52aa485969dd92928859eb 72 Pfam PF10837 Protein of unknown function (DUF2575) 2 72 6.0E-48 T 10-03-2017 IPR020105 Uncharacterised protein family YaaY RG49_RS11750 ba6191e60d52aa485969dd92928859eb 72 ProDom PD056390 YAAY CYTOPLASMIC STY0053 ECS0027 3 72 4.0E-34 T 10-03-2017 IPR020105 Uncharacterised protein family YaaY RG49_RS07570 00e50842c75dfe03d72cefa5f30827fb 78 Pfam PF13808 DDE_Tnp_1-associated 7 77 3.7E-26 T 10-03-2017 IPR032806 H repeat-associated protein, N-terminal RG49_RS24545 39afb12f8e36ff9141ee3713e61b64bd 35 Hamap MF_01362 UPF0387 membrane protein YohO [yohO]. 1 35 19.177 T 10-03-2017 IPR020870 Uncharacterised protein family UPF0387, membrane GO:0005886 RG49_RS10120 70160c975050db305a4451adbe40e0fe 152 Pfam PF03230 Antirestriction protein 60 152 4.6E-39 T 10-03-2017 IPR004914 Antirestriction protein RG49_RS10120 70160c975050db305a4451adbe40e0fe 152 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 58 152 3.0E-48 T 10-03-2017 IPR004914 Antirestriction protein RG49_RS11770 78a544a97c12a8410a0c2a54215be060 319 SUPERFAMILY SSF49401 202 319 3.33E-9 T 10-03-2017 IPR008966 Adhesion domain RG49_RS11770 78a544a97c12a8410a0c2a54215be060 319 Gene3D G3DSA:2.60.40.1090 199 319 3.5E-8 T 10-03-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 RG49_RS18900 ed5d89bf2347e407b119f5df4193209b 346 Pfam PF03773 Predicted permease 73 340 9.0E-29 T 10-03-2017 IPR005524 Predicted permease DUF318 RG49_RS18900 ed5d89bf2347e407b119f5df4193209b 346 Pfam PF03773 Predicted permease 56 151 4.9E-13 T 10-03-2017 IPR005524 Predicted permease DUF318 RG49_RS10140 ae0c7e7177f1d843e6d0a144e6dea5dc 113 Pfam PF06755 CbtA_toxin of type IV toxin-antitoxin system 1 112 2.6E-64 T 10-03-2017 IPR009610 CbtA toxin of type IV toxin-antitoxin system RG49_RS19200 57cdfd3896ab8ea7ca2141046ebb7fba 130 Pfam PF07681 DoxX 9 87 7.2E-18 T 10-03-2017 IPR032808 DoxX family RG49_RS02250 077736ab1e4cf81c0122484573b878da 140 Pfam PF06163 Bacterial protein of unknown function (DUF977) 2 136 3.1E-32 T 10-03-2017 IPR010382 Protein of unknown function DUF977 RG49_RS07595 6c5a711ba684b1984664e98a5dcacbc4 68 Pfam PF10725 Protein of unknown function (DUF2517) 4 63 4.1E-34 T 10-03-2017 IPR019663 Uncharacterised protein YbfA RG49_RS15140 d218bc05c06dbbc0aa77508fc93792a1 235 Pfam PF04340 Protein of unknown function, DUF484 11 232 1.8E-89 T 10-03-2017 IPR007435 Protein of unknown function DUF484 RG49_RS17745 76ba5d1213b18a531b417abd1f61de8f 55 Pfam PF13978 Protein of unknown function (DUF4223) 1 54 9.2E-36 T 10-03-2017 IPR025318 Protein of unknown function DUF4223 RG49_RS24955 3cea1747086f8e2bdda5cae1af863503 492 Pfam PF13440 Polysaccharide biosynthesis protein 31 325 1.0E-67 T 10-03-2017 RG49_RS08855 b07e61a211cd339d73ef424fe70b80af 190 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 46 150 5.9E-42 T 10-03-2017 RG49_RS10255 a78b50ed8fe05aff75fb2a60abee0e13 498 Pfam PF04984 Phage tail sheath protein 8 489 1.2E-75 T 10-03-2017 IPR007067 Tail sheath protein RG49_RS10255 a78b50ed8fe05aff75fb2a60abee0e13 498 PIRSF PIRSF007349 1 491 2.9E-202 T 10-03-2017 IPR007067 Tail sheath protein RG49_RS19215 fa1a4201301f9503dd5d51aa06fb8a10 101 Pfam PF05957 Bacterial protein of unknown function (DUF883) 9 101 5.8E-31 T 10-03-2017 IPR010279 Protein of unknown function DUF883, ElaB RG49_RS10035 c3f91de9bd9a10e7c49f16dc8cd3efc3 381 Gene3D G3DSA:3.30.160.100 20 103 7.5E-4 T 10-03-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 RG49_RS19065 c03b3ade5a862334add5f64e2f8095eb 240 Pfam PF11726 Protein of unknown function (DUF3296) 52 213 1.5E-16 T 10-03-2017 IPR021723 Inovirus Gp2 RG49_RS19865 591944e19cd523868dc3adb6a949839f 359 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 354 1.2E-92 T 10-03-2017 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 RG49_RS19865 591944e19cd523868dc3adb6a949839f 359 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 352 3.0E-61 T 10-03-2017 IPR005495 Permease LptG/LptF-related GO:0016021 RG49_RS12740 63c4f8f85f6e4434568e4a12539260fc 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 304 8.9E-44 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS09245 7f96e8cdcba5b70264df8173cbad350b 102 ProDom PD068630 MEMBRANE INNER YAIY TRANSMEMBRANE 1 102 2.0E-54 T 10-03-2017 IPR020513 Uncharacterised protein family, inner membrane YaiY GO:0016021 RG49_RS09245 7f96e8cdcba5b70264df8173cbad350b 102 Pfam PF10954 Protein of unknown function (DUF2755) 1 101 9.2E-50 T 10-03-2017 IPR020513 Uncharacterised protein family, inner membrane YaiY GO:0016021 RG49_RS23450 5330ef2469142976e5ec195c1e8c17c5 92 Pfam PF08891 YfcL protein 4 87 4.7E-35 T 10-03-2017 IPR014987 Uncharacterised protein family YfcL RG49_RS25345 c1bdad2c63efefacd8c358f8231658b5 546 TIGRFAM TIGR00797 matE: MATE efflux family protein 99 503 2.1E-69 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS25345 c1bdad2c63efefacd8c358f8231658b5 546 Pfam PF01554 MatE 329 490 2.7E-20 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS25345 c1bdad2c63efefacd8c358f8231658b5 546 Pfam PF01554 MatE 99 258 9.5E-37 T 10-03-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 RG49_RS23650 3196ce19e8d8d88083060387212e6a7a 147 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 9 126 19.913 T 10-03-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 RG49_RS23650 3196ce19e8d8d88083060387212e6a7a 147 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 28 125 5.0E-31 T 10-03-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 RG49_RS02460 77de495ec4dd29aefd5d286a8aca9cd2 215 Pfam PF06805 Bacteriophage lambda tail assembly protein I 14 97 2.8E-28 T 10-03-2017 IPR010654 Bacteriophage lambda tail assembly I RG49_RS01280 3053db65ad689963a9ed3c8eb81b43dd 161 PIRSF PIRSF034445 1 152 4.5E-30 T 10-03-2017 IPR012899 LTXXQ motif family protein GO:0042597 RG49_RS01280 3053db65ad689963a9ed3c8eb81b43dd 161 Pfam PF07813 LTXXQ motif family protein 46 141 2.2E-23 T 10-03-2017 IPR012899 LTXXQ motif family protein GO:0042597 RG49_RS05055 244f900a709d08330dbbbe6a157ce87b 399 Pfam PF02687 FtsX-like permease family 270 392 4.5E-16 T 10-03-2017 IPR003838 ABC transporter permease protein domain GO:0016020 RG49_RS05055 244f900a709d08330dbbbe6a157ce87b 399 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 399 4.0E-148 T 10-03-2017 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 RG49_RS05055 244f900a709d08330dbbbe6a157ce87b 399 Gene3D G3DSA:2.40.40.20 132 164 3.7E-4 T 10-03-2017 RG49_RS05055 244f900a709d08330dbbbe6a157ce87b 399 Pfam PF12704 MacB-like periplasmic core domain 27 205 1.9E-13 T 10-03-2017 IPR025857 MacB-like periplasmic core domain RG49_RS12770 e57659b43ea4671a588b5dc132e2a80f 1259 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 923 1259 1.4E-69 T 10-03-2017 IPR007452 Translocation and assembly module TamB RG49_RS09255 ff46144aaa0fd5275bbe0ee78e5e4538 406 Pfam PF05992 SbmA/BacA-like family 80 393 1.7E-166 T 10-03-2017 IPR009248 SbmA/BacA-like GO:0005215|GO:0006810|GO:0016021 RG49_RS09255 ff46144aaa0fd5275bbe0ee78e5e4538 406 SUPERFAMILY SSF90123 78 389 3.24E-6 T 10-03-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 RG49_RS01300 80ee582081650fc1058f330ea6212f00 112 Pfam PF04355 SmpA / OmlA family 33 96 4.0E-11 T 10-03-2017 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 RG49_RS18135 1d203ab277962fd871b609851310cbe3 122 Pfam PF09350 Domain of unknown function (DUF1992) 7 72 1.1E-23 T 10-03-2017 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain RG49_RS18320 345eb4fa521090ef985ca04cddd5ea81 80 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 1 80 2.0E-27 T 10-03-2017 IPR010398 Protein of unknown function DUF997 RG49_RS18320 345eb4fa521090ef985ca04cddd5ea81 80 Pfam PF06196 Protein of unknown function (DUF997) 7 77 3.1E-31 T 10-03-2017 IPR010398 Protein of unknown function DUF997 RG49_RS20620 44f6b8455c701720bec2b49bbf92c409 278 Gene3D G3DSA:1.50.10.10 204 249 3.0E-6 T 10-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 RG49_RS20620 44f6b8455c701720bec2b49bbf92c409 278 Gene3D G3DSA:1.50.10.10 110 170 3.0E-6 T 10-03-2017 IPR012341 Six-hairpin glycosidase GO:0003824 RG49_RS20620 44f6b8455c701720bec2b49bbf92c409 278 SUPERFAMILY SSF48208 104 268 4.76E-14 T 10-03-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 RG49_RS16985 67a5dda29807a1312cc7bc73846e624e 190 Pfam PF03729 Short repeat of unknown function (DUF308) 27 97 5.3E-12 T 10-03-2017 IPR005325 Protein of unknown function DUF308, membrane RG49_RS16985 67a5dda29807a1312cc7bc73846e624e 190 Pfam PF03729 Short repeat of unknown function (DUF308) 84 153 4.8E-8 T 10-03-2017 IPR005325 Protein of unknown function DUF308, membrane RG49_RS03320 c644a0db127a3ef79f5e313345406a27 57 ProDom PD052090 YDCA PRECURSOR SIGNAL ECS2024 1 57 3.0E-26 T 10-03-2017 RG49_RS12995 9aa45ee7f805e22a5ebb8154609c2108 132 Pfam PF03994 Domain of Unknown Function (DUF350) 13 65 2.7E-12 T 10-03-2017 IPR007140 Protein of unknown function DUF350 RG49_RS12995 9aa45ee7f805e22a5ebb8154609c2108 132 Pfam PF03994 Domain of Unknown Function (DUF350) 78 130 4.1E-7 T 10-03-2017 IPR007140 Protein of unknown function DUF350 RG49_RS16610 4f7ef4f0d7fc188abb5ab29c6fbe5bc0 393 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 383 6.3E-50 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS00020 f63325d1b682a48571ce979a37c9c1ae 176 Pfam PF01292 Prokaryotic cytochrome b561 3 173 1.1E-18 T 10-03-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 RG49_RS00020 f63325d1b682a48571ce979a37c9c1ae 176 SUPERFAMILY SSF81342 2 173 6.59E-28 T 10-03-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 RG49_RS00390 0ad3439040d2bb9159091a01236d0ec6 107 Pfam PF13992 YecR-like lipoprotein 27 98 8.6E-28 T 10-03-2017 IPR025731 YecR-like lipoprotein RG49_RS00255 64ce94611ad24a457523dab461191fcb 137 Pfam PF13987 YedD-like protein 25 129 1.2E-54 T 10-03-2017 IPR025596 YedD-like protein RG49_RS13430 54afcb53e71a51b427a3daec7ef83d49 35 Pfam PF12035 Protein of unknown function (DUF3521) 1 28 4.2E-7 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS17625 86f73b1fba638fb86a227b2c13d9130b 134 Pfam PF10748 Protein of unknown function (DUF2531) 3 134 7.7E-70 T 10-03-2017 IPR019684 Protein of unknown function DUF2531 RG49_RS15515 e48c3498685547481d38ac4b6ecf0af5 126 Pfam PF03899 ATP synthase I chain 13 108 1.0E-14 T 10-03-2017 IPR005598 ATP synthase protein I RG49_RS20125 7ad30a2f9c07ad0dff873afcdc2e3d07 188 Pfam PF02325 YGGT family 10 78 8.1E-22 T 10-03-2017 IPR003425 CCB3/YggT GO:0016020 RG49_RS20125 7ad30a2f9c07ad0dff873afcdc2e3d07 188 Pfam PF02325 YGGT family 104 167 7.7E-16 T 10-03-2017 IPR003425 CCB3/YggT GO:0016020 RG49_RS20275 c705b24f3b3aa1fbba4c3871f469db86 211 Hamap MF_01901 Arginine exporter protein ArgO [argO]. 1 205 39.783 T 10-03-2017 IPR023445 Arginine exporter protein ArgO, enterobacteria GO:0015181|GO:0015809 RG49_RS20275 c705b24f3b3aa1fbba4c3871f469db86 211 TIGRFAM TIGR00948 2a75: L-lysine exporter 15 191 3.8E-73 T 10-03-2017 IPR004777 L-lysine exporter/arginine exporter GO:0016021 RG49_RS20275 c705b24f3b3aa1fbba4c3871f469db86 211 Pfam PF01810 LysE type translocator 14 201 3.2E-57 T 10-03-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 RG49_RS19505 0087e1591cf4e7494fadfb8076c46772 209 Pfam PF07290 Protein of unknown function (DUF1449) 8 202 4.1E-75 T 10-03-2017 IPR010840 Protein of unknown function DUF1449 RG49_RS17000 61db44ead7d92cfa989ac478e06fc1d5 215 PRINTS PR01837 MgtC/SapB protein signature 65 87 5.8E-43 T 10-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 RG49_RS17000 61db44ead7d92cfa989ac478e06fc1d5 215 PRINTS PR01837 MgtC/SapB protein signature 12 31 5.8E-43 T 10-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 RG49_RS17000 61db44ead7d92cfa989ac478e06fc1d5 215 PRINTS PR01837 MgtC/SapB protein signature 31 49 5.8E-43 T 10-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 RG49_RS17000 61db44ead7d92cfa989ac478e06fc1d5 215 PRINTS PR01837 MgtC/SapB protein signature 92 116 5.8E-43 T 10-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 RG49_RS17000 61db44ead7d92cfa989ac478e06fc1d5 215 Pfam PF02308 MgtC family 9 136 4.9E-37 T 10-03-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 RG49_RS17230 5f7576ae25377f28389d220901852c51 208 Pfam PF07947 YhhN-like protein 26 206 3.0E-42 T 10-03-2017 IPR012506 YhhN-like GO:0016021 RG49_RS25180 e5ecfba48af92c337d81ebfac5cc08cb 91 SUPERFAMILY SSF52540 6 84 7.64E-9 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS25180 e5ecfba48af92c337d81ebfac5cc08cb 91 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 1 85 2.6E-24 T 10-03-2017 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 RG49_RS25180 e5ecfba48af92c337d81ebfac5cc08cb 91 Gene3D G3DSA:3.40.50.300 7 84 2.8E-8 T 10-03-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase RG49_RS00525 4a1b580474248a74e937551b70dff96e 162 Pfam PF07007 Protein of unknown function (DUF1311) 35 145 3.3E-19 T 10-03-2017 IPR009739 Protein of unknown function DUF1311 RG49_RS08385 b03a56e720e3e19b9577b37a37c5c716 296 Pfam PF14488 Domain of unknown function (DUF4434) 21 186 1.5E-31 T 10-03-2017 IPR027849 Protein of unknown function DUF4434 RG49_RS14395 693b46070a0353eaae1f2ca03b6ddb00 39 Pfam PF15954 Domain of unknown function (DUF4759) 5 38 2.1E-18 T 10-03-2017 IPR031873 Domain of unknown function DUF4759 RG49_RS13585 8c70bc72d5e8567c35245925f9875e29 683 Pfam PF04632 Fusaric acid resistance protein family 36 532 1.8E-31 T 10-03-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 RG49_RS06550 7b95b5dbe79c49baf3b63c265ad9be65 161 PIRSF PIRSF029208 1 154 1.5E-63 T 10-03-2017 IPR016912 Bacteriophage P2, GpU RG49_RS06550 7b95b5dbe79c49baf3b63c265ad9be65 161 Pfam PF06995 Phage P2 GpU 6 125 4.7E-45 T 10-03-2017 IPR009734 Myoviridae, GpU RG49_RS07355 029ef8d31b6e4eba21b7bb703a4276ae 142 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 141 2.4E-23 T 10-03-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 RG49_RS07355 029ef8d31b6e4eba21b7bb703a4276ae 142 TIGRFAM TIGR02801 tolR: protein TolR 13 140 1.4E-39 T 10-03-2017 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 RG49_RS13555 2892364ec80d127a376a1c557ffffca6 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 318 1.1E-47 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS22685 06bbef67f05e6a9bce12f6fea70defe0 353 Pfam PF01594 Domain of unknown function DUF20 20 345 4.6E-86 T 10-03-2017 IPR002549 Transmembrane protein TqsA-like RG49_RS20485 91e4634553e74b24c052e927f8591eea 455 Pfam PF00860 Permease family 32 415 1.4E-78 T 10-03-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 RG49_RS17155 b63fb11714ba2af00abcadccf55dc08f 127 Pfam PF15631 NTF2 fold immunity protein 60 127 1.9E-23 T 10-03-2017 IPR028921 NTF2 fold domain RG49_RS17615 15cdced7c289825b0288cd8854133daf 179 Pfam PF05137 Fimbrial assembly protein (PilN) 99 169 2.6E-8 T 10-03-2017 IPR007813 Fimbrial assembly PilN RG49_RS15105 00114b18d6a5d476c5945aa918bf782a 126 Pfam PF10947 Protein of unknown function (DUF2628) 13 116 6.7E-11 T 10-03-2017 IPR024399 Protein of unknown function DUF2628 RG49_RS15105 00114b18d6a5d476c5945aa918bf782a 126 ProDom PD031864 YIGF SIMILAR ESCHERICHIA COLI MEMBRANE XCC4223 XAC4357 XAC2195 1 126 2.0E-68 T 10-03-2017 RG49_RS04720 ae5b826c1faba4566de05bf2241c2304 510 Pfam PF04293 SpoVR like protein 19 450 8.0E-177 T 10-03-2017 IPR007390 Sporulation stage V, protein R RG49_RS21890 bea5629b47386eb8650c08fb156d06c0 196 Pfam PF10554 Ash protein family 22 140 7.2E-16 T 10-03-2017 IPR018880 Bacteriophage P4, Ash protein RG49_RS14725 d893c87f673831389b65740e236439fc 72 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 3.8E-11 T 10-03-2017 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 RG49_RS19860 3423d818fb0d4109d0c4b412b01b73ab 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 344 7.2E-54 T 10-03-2017 IPR005495 Permease LptG/LptF-related GO:0016021 RG49_RS19860 3423d818fb0d4109d0c4b412b01b73ab 356 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 4 345 1.2E-95 T 10-03-2017 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 RG49_RS13180 8e45ccea21f648f7711eaa8914e50a61 48 Pfam PF08085 Entericidin EcnA/B family 23 43 1.6E-8 T 10-03-2017 IPR012556 Entericidin A/B GO:0009636|GO:0016020 RG49_RS05810 ba88ee2c8ffa535d78ee61ad5a098427 30 Pfam PF08173 Membrane bound YbgT-like protein 1 25 2.7E-11 T 10-03-2017 IPR012994 Membrane bound YbgT-like RG49_RS10280 ee76ab80ea1f798304478e867c587f9d 107 Pfam PF05135 Phage gp6-like head-tail connector protein 4 103 4.2E-19 T 10-03-2017 IPR021146 Phage gp6-like head-tail connector protein RG49_RS24565 354ab63b41dba23df9aec162e9e69519 156 Pfam PF07308 Protein of unknown function (DUF1456) 86 150 1.1E-20 T 10-03-2017 IPR009921 Domain of unknown function DUF1456 RG49_RS24565 354ab63b41dba23df9aec162e9e69519 156 Pfam PF07308 Protein of unknown function (DUF1456) 4 70 2.2E-25 T 10-03-2017 IPR009921 Domain of unknown function DUF1456 RG49_RS12610 3d39feede726890bf144e272c10d8422 398 Pfam PF05987 Bacterial protein of unknown function (DUF898) 13 367 4.7E-46 T 10-03-2017 IPR010295 Protein of unknown function DUF898 RG49_RS23475 8c427423cdce9398529d1ea8d7c2f4d3 331 PIRSF PIRSF020588 2 331 5.4E-153 T 10-03-2017 IPR023597 Flagellar regulator Flk GO:0010468|GO:0031224 RG49_RS19545 5ed3d2d902d1744d288f3c3937079a81 56 Pfam PF13260 Protein of unknown function (DUF4051) 1 50 5.2E-29 T 10-03-2017 IPR025125 Protein of unknown function DUF4051 RG49_RS10200 37cb9865d412bb336ae8e9b02ad10f2a 194 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 12 192 8.1E-42 T 10-03-2017 IPR018755 Bacteriophage Mu, Gp48 RG49_RS15460 9f0be77d9917763c8c42a8459a9228f5 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 313 1.8E-50 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS20320 7507a58cf122b99e516842d7e69272c9 76 SUPERFAMILY SSF53850 14 74 5.79E-7 T 10-03-2017 RG49_RS06635 d764a6f53acae8d197bc36adaa6247a2 150 Pfam PF06891 P2 phage tail completion protein R (GpR) 9 126 1.9E-43 T 10-03-2017 IPR009678 Bacteriophage tail completion protein R RG49_RS23515 9117bbc343b0b643f07748ca67d2c7ad 162 Pfam PF02674 Colicin V production protein 4 141 1.6E-35 T 10-03-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 RG49_RS12170 768cbc3dfbbec52b5c7bb44cba024e32 157 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 19 147 1.3E-28 T 10-03-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component RG49_RS00820 50742b438fde18c9298f5c246d366197 79 Pfam PF13996 YobH-like protein 2 71 2.4E-38 T 10-03-2017 IPR025611 YobH-like protein RG49_RS25285 8a3225ce8bd9e23194cba7fdff5d1d57 110 Pfam PF15631 NTF2 fold immunity protein 47 110 2.6E-17 T 10-03-2017 IPR028921 NTF2 fold domain RG49_RS22840 e225df92eaca90364c47c581e790371b 347 Pfam PF06674 Protein of unknown function (DUF1176) 25 347 5.8E-98 T 10-03-2017 IPR009560 Protein of unknown function DUF1176 RG49_RS04550 0dc3e987eab4546d4cc5b2c564a7e27f 35 Pfam PF13940 Toxin Ldr, type I toxin-antitoxin system 1 35 1.2E-24 T 10-03-2017 IPR025253 Type I toxin-antitoxin system, toxin Ldr RG49_RS13300 f493d69733f522a4c27501a938b03886 98 Pfam PF11080 Protein of unknown function (DUF2622) 5 94 3.5E-31 T 10-03-2017 IPR022597 Endoribonuclease GhoS GO:0004521 RG49_RS10190 1209ed6336347e99ef7bfaf1893428e6 200 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 78 199 5.2E-26 T 10-03-2017 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly RG49_RS13910 fbb6498f0e2700d373910bd08ba7709a 92 Pfam PF17089 Uncharacterised protein family 1 92 1.0E-65 T 10-03-2017 IPR031382 Uncharacterised protein YjbT RG49_RS03790 c74ef7009315a1d8e1f7a1bfe045d258 71 Pfam PF06806 Putative excisionase (DUF1233) 5 69 1.6E-19 T 10-03-2017 IPR009634 Bacteriophage 933W, Xis excisionase RG49_RS05820 5994037a8161b9abc63787fdb520c8a5 514 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 501 5.3E-177 T 10-03-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 RG49_RS12295 5be77fe4e8ef81fc7ebbf8505edf48ea 74 Pfam PF12035 Protein of unknown function (DUF3521) 7 38 1.3E-7 T 10-03-2017 IPR021909 Protein of unknown function DUF3521 RG49_RS17240 731798065aac5c810116fb4002e87f6c 89 Pfam PF06611 Protein of unknown function (DUF1145) 1 58 2.4E-27 T 10-03-2017 IPR009525 Protein of unknown function DUF1145 RG49_RS04290 ec654bea684d593746da27b5cc2c198e 59 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 32 52 5.0E-9 T 10-03-2017 IPR019626 Stress-induced protein, KGG, repeat RG49_RS04290 ec654bea684d593746da27b5cc2c198e 59 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 10 30 1.5E-9 T 10-03-2017 IPR019626 Stress-induced protein, KGG, repeat RG49_RS23110 b8bdea31c2cf66019b18d6f8739081a3 52 TIGRFAM TIGR03510 XapX: XapX domain 4 50 1.5E-18 T 10-03-2017 IPR020017 XapX domain RG49_RS12745 2f2a2815f07ace179826bf145eee1556 340 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 320 6.6E-48 T 10-03-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 RG49_RS10250 58e17a50feb463d32d5a899c9cd2f73a 118 Pfam PF10618 Phage tail tube protein 1 115 2.0E-39 T 10-03-2017 IPR019596 Bacteriophage Mu, GpM, tail tube RG49_RS19185 5457883fbb5e31e291642c74cdd194af 118 Pfam PF05656 Protein of unknown function (DUF805) 11 113 4.6E-33 T 10-03-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 RG49_RS16415 9e0251c1867e1ba3e9df366e7925c3bc 69 Gene3D G3DSA:1.20.58.250 15 63 1.5E-9 T 10-03-2017 IPR011326 Homologue of theta DNA polymerase III RG49_RS17610 97f5eef863ffe960d3e1542d8ec96b7f 259 SUPERFAMILY SSF53067 34 164 7.12E-6 T 10-03-2017 RG49_RS03280 6bf54baee61b13e781585b52912ea80c 74 Pfam PF04325 Protein of unknown function (DUF465) 19 66 5.9E-14 T 10-03-2017 IPR007420 Protein of unknown function DUF465 RG49_RS23910 9f732ac1589c278a9bb5309f30e2c3c2 68 ProDom PD055259 TRANSCRIPTION TRANSCRIPTIONAL REGULATOR DNA-BINDING ACTIVATOR REGULATION YFAH FAMILY LYSR REGULATOR 1 68 5.0E-29 T 10-03-2017 IPR020093 Uncharacterised domain YfaH, C-terminal RG49_RS12350 e1be2efdebafdb2189690c233440a7a5 227 Pfam PF07670 Nucleoside recognition 85 178 4.2E-6 T 10-03-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 RG49_RS19230 c73ca6950ef645f2f22a23b5c138d8f4 220 Pfam PF09335 SNARE associated Golgi protein 48 173 7.8E-22 T 10-03-2017 IPR032816 SNARE associated Golgi protein