locus-tag	class	description
ECHS_RS00010	COG0527	aspartate kinase activity
ECHS_RS00010	COG0460	homoserine dehydrogenase
ECHS_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ECHS_RS00040	COG1115	amino acid carrier protein
ECHS_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECHS_RS00055	COG1584	GPR1 FUN34 yaaH family protein
ECHS_RS00060	COG4735	regulation of single-species biofilm formation
ECHS_RS00080	COG3385	transposase activity
ECHS_RS00095	COG0583	DNA-binding transcription factor activity
ECHS_RS00130	COG0196	riboflavin kinase activity
ECHS_RS00145	COG1047	Peptidyl-prolyl cis-trans
ECHS_RS00175	COG0505	Belongs to the CarA family
ECHS_RS00180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ECHS_RS00235	COG0644	oxidoreductase
ECHS_RS00240	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECHS_RS00245	COG2271	Major facilitator Superfamily
ECHS_RS00260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ECHS_RS00285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECHS_RS00290	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECHS_RS00295	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ECHS_RS00300	COG0564	pseudouridine synthase activity
ECHS_RS00310	COG0417	DNA replication proofreading
ECHS_RS00315	COG0235	Class ii aldolase
ECHS_RS00330	COG4977	sequence-specific DNA binding
ECHS_RS00335	COG0586	Pfam SNARE associated Golgi protein
ECHS_RS00345	COG1178	ABC-type Fe3 transport system permease component
ECHS_RS00350	COG4143	(ABC) transporter
ECHS_RS00355	COG4533	DNA binding
ECHS_RS00365	COG2814	Major facilitator Superfamily
ECHS_RS00380	COG0473	3-isopropylmalate dehydrogenase activity
ECHS_RS00395	COG0583	DNA-binding transcription factor activity
ECHS_RS00400	COG0028	Belongs to the TPP enzyme family
ECHS_RS00405	COG0440	acetolactate synthase activity
ECHS_RS00415	COG1609	Transcriptional regulator
ECHS_RS00430	COG3116	cell division
ECHS_RS00435	COG0768	penicillin binding
ECHS_RS00440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECHS_RS00445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ECHS_RS00455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ECHS_RS00460	COG0772	Belongs to the SEDS family
ECHS_RS00475	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECHS_RS00480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ECHS_RS00485	COG0849	cell division
ECHS_RS00490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ECHS_RS00510	COG0494	nUDIX hydrolase
ECHS_RS00530	COG0237	dephospho-CoA kinase activity
ECHS_RS00540	COG1459	type II secretion system
ECHS_RS00545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECHS_RS00550	COG4969	Belongs to the N-Me-Phe pilin family
ECHS_RS00560	COG0157	Belongs to the NadC ModD family
ECHS_RS00565	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECHS_RS00570	COG3725	Membrane protein required for beta-lactamase induction
ECHS_RS00575	COG1113	amino acid transport
ECHS_RS00580	COG2186	Transcriptional regulator
ECHS_RS00585	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ECHS_RS00590	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECHS_RS00595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECHS_RS00600	COG3064	Membrane
ECHS_RS00605	COG1049	propionate catabolic process, 2-methylcitrate cycle
ECHS_RS00630	COG2132	Multicopper oxidase
ECHS_RS00635	COG4993	Dehydrogenase
ECHS_RS00640	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ECHS_RS00645	COG0288	reversible hydration of carbon dioxide
ECHS_RS00650	COG1131	(ABC) transporter
ECHS_RS00655	COG0842	Transport permease protein
ECHS_RS00660	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS00665	COG0726	polysaccharide deacetylase
ECHS_RS00690	COG3539	Fimbrial protein
ECHS_RS00695	COG3539	Fimbrial protein
ECHS_RS00700	COG2801	Transposase and inactivated derivatives
ECHS_RS00705	COG2963	transposase activity
ECHS_RS00710	COG3121	Chaperone
ECHS_RS00715	COG3539	Fimbrial protein
ECHS_RS00720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ECHS_RS00725	COG0617	tRNA 3'-terminal CCA addition
ECHS_RS00735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECHS_RS00745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ECHS_RS00750	COG1643	Atp-dependent helicase
ECHS_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ECHS_RS00765	COG4774	siderophore transport
ECHS_RS00770	COG1120	ATPase activity
ECHS_RS00775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECHS_RS00780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECHS_RS00800	COG2860	membrane
ECHS_RS00805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECHS_RS00820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECHS_RS00825	COG3835	regulator
ECHS_RS00845	COG0024	Methionine aminopeptidase
ECHS_RS00870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ECHS_RS00875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ECHS_RS00880	COG0575	Belongs to the CDS family
ECHS_RS00885	COG0750	zinc metalloprotease
ECHS_RS00895	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ECHS_RS00900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECHS_RS00925	COG0587	DNA-directed DNA polymerase activity
ECHS_RS00935	COG1982	Orn Lys Arg decarboxylase major
ECHS_RS00940	COG0346	lactoylglutathione lyase activity
ECHS_RS00950	COG4568	rho-dependent transcription termination
ECHS_RS00960	COG4681	YaeQ
ECHS_RS00965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECHS_RS00970	COG3015	lipoprotein NlpE involved in copper resistance
ECHS_RS00975	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS00980	COG0791	NLP P60 protein
ECHS_RS00990	COG1720	tRNA m6t6A37 methyltransferase activity
ECHS_RS01000	COG1464	Belongs to the NlpA lipoprotein family
ECHS_RS01005	COG2011	ABC-type metal ion transport system permease component
ECHS_RS01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ECHS_RS01015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECHS_RS01050	COG0656	L-ascorbic acid biosynthetic process
ECHS_RS01055	COG0583	DNA-binding transcription factor activity
ECHS_RS01065	COG2226	methyltransferase
ECHS_RS01070	COG1388	LysM domain
ECHS_RS01070	COG0741	lytic transglycosylase activity
ECHS_RS01080	COG2226	methyltransferase
ECHS_RS01090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECHS_RS01110	COG4104	PAAR repeat-containing protein
ECHS_RS01115	COG3157	Type VI secretion system effector, Hcp
ECHS_RS01215	COG3209	COG3209 Rhs family protein
ECHS_RS01230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECHS_RS01240	COG1960	acyl-CoA dehydrogenase activity
ECHS_RS01250	COG0121	glutamine amidotransferase
ECHS_RS01255	COG3034	peptidoglycan biosynthetic process
ECHS_RS01260	COG3041	Addiction module toxin RelE StbE family
ECHS_RS01265	COG3077	Addiction module antitoxin, RelB DinJ family
ECHS_RS01270	COG0791	NLP P60 protein
ECHS_RS01300	COG0454	-acetyltransferase
ECHS_RS01305	COG1690	Belongs to the RtcB family
ECHS_RS01310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECHS_RS01315	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECHS_RS01335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECHS_RS01355	COG0582	viral genome integration into host DNA
ECHS_RS01395	COG2963	transposase activity
ECHS_RS01400	COG2801	Transposase and inactivated derivatives
ECHS_RS01405	COG3723	Recombinational DNA repair protein, rece pathway
ECHS_RS01460	COG0305	Participates in initiation and elongation during chromosome replication
ECHS_RS01525	COG3646	Phage regulatory protein
ECHS_RS01540	COG1783	phage Terminase large subunit
ECHS_RS01620	COG2963	transposase activity
ECHS_RS01625	COG2801	Transposase and inactivated derivatives
ECHS_RS01655	COG0582	viral genome integration into host DNA
ECHS_RS01660	COG0582	viral genome integration into host DNA
ECHS_RS01745	COG2963	transposase activity
ECHS_RS01750	COG2801	Transposase and inactivated derivatives
ECHS_RS01780	COG1388	LysM domain
ECHS_RS01785	COG2207	Transcriptional regulator
ECHS_RS01785	COG3708	Transcriptional regulator
ECHS_RS01790	COG0656	L-ascorbic acid biosynthetic process
ECHS_RS01795	COG3059	membrane
ECHS_RS01805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECHS_RS01810	COG2207	Transcriptional regulator
ECHS_RS01815	COG0247	lactate metabolic process
ECHS_RS01820	COG1139	Iron-sulfur cluster binding protein
ECHS_RS01825	COG1556	Lactate utilization protein
ECHS_RS01840	COG3468	outer membrane autotransporter barrel domain protein
ECHS_RS01850	COG2771	luxR family
ECHS_RS01850	COG2200	EAL domain
ECHS_RS01855	COG0582	viral genome integration into host DNA
ECHS_RS01890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECHS_RS01900	COG2771	luxR family
ECHS_RS01900	COG2200	EAL domain
ECHS_RS01905	COG0583	DNA-binding transcription factor activity
ECHS_RS01915	COG0666	response to abiotic stimulus
ECHS_RS01925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECHS_RS01930	COG1304	FMN binding
ECHS_RS01935	COG0549	Belongs to the carbamate kinase family
ECHS_RS01940	COG0402	S-adenosylhomocysteine deaminase activity
ECHS_RS01950	COG1879	ABC-type sugar transport system periplasmic component
ECHS_RS01955	COG1129	ABC transporter
ECHS_RS01960	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS01970	COG1064	alcohol dehydrogenase
ECHS_RS01985	COG1280	lysine exporter protein (LysE YggA)
ECHS_RS01995	COG3829	transcription factor binding
ECHS_RS02000	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ECHS_RS02005	COG0372	Belongs to the citrate synthase family
ECHS_RS02010	COG2079	MmgE PrpD family protein
ECHS_RS02015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECHS_RS02020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ECHS_RS02025	COG0402	S-adenosylhomocysteine deaminase activity
ECHS_RS02030	COG0583	DNA-binding transcription factor activity
ECHS_RS02035	COG0288	reversible hydration of carbon dioxide
ECHS_RS02045	COG2807	transmembrane transport
ECHS_RS02050	COG2223	nitrite transmembrane transporter activity
ECHS_RS02060	COG1609	Transcriptional regulator
ECHS_RS02065	COG1414	Transcriptional regulator
ECHS_RS02100	COG2814	Major facilitator Superfamily
ECHS_RS02105	COG3122	Protein conserved in bacteria
ECHS_RS02110	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS02140	COG1215	transferase activity, transferring glycosyl groups
ECHS_RS02145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ECHS_RS02150	COG4521	taurine ABC transporter
ECHS_RS02160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECHS_RS02165	COG2175	clavaminate synthase activity
ECHS_RS02170	COG0113	porphobilinogen synthase activity
ECHS_RS02180	COG2801	Transposase and inactivated derivatives
ECHS_RS02185	COG2963	transposase activity
ECHS_RS02190	COG3468	outer membrane autotransporter barrel domain protein
ECHS_RS02195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECHS_RS02200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECHS_RS02210	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ECHS_RS02230	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECHS_RS02245	COG1785	Belongs to the alkaline phosphatase family
ECHS_RS02255	COG3706	GGDEF domain
ECHS_RS02260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ECHS_RS02285	COG4126	flavin adenine dinucleotide binding
ECHS_RS02305	COG1940	carbohydrate kinase activity
ECHS_RS02310	COG2814	Major facilitator Superfamily
ECHS_RS02315	COG0419	ATPase involved in DNA repair
ECHS_RS02320	COG0420	3'-5' exonuclease activity
ECHS_RS02325	COG0745	RESPONSE REGULATOR receiver
ECHS_RS02330	COG5002	protein histidine kinase activity
ECHS_RS02335	COG1114	Component of the transport system for branched-chain amino acids
ECHS_RS02340	COG1113	amino acid transport
ECHS_RS02345	COG0366	Alpha amylase catalytic
ECHS_RS02365	COG1862	Preprotein translocase
ECHS_RS02370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECHS_RS02375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECHS_RS02380	COG1403	HNH endonuclease
ECHS_RS02390	COG3248	Nucleoside-binding outer membrane protein
ECHS_RS02395	COG4238	major outer membrane lipoprotein
ECHS_RS02405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECHS_RS02405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECHS_RS02420	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ECHS_RS02425	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ECHS_RS02430	COG0667	Aldo Keto reductase
ECHS_RS02440	COG0142	geranyltranstransferase activity
ECHS_RS02455	COG0693	protein deglycase activity
ECHS_RS02460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECHS_RS02470	COG2814	Major facilitator Superfamily
ECHS_RS02495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ECHS_RS02500	COG1845	cytochrome c oxidase, subunit III
ECHS_RS02505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECHS_RS02510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ECHS_RS02515	COG2223	nitrite transmembrane transporter activity
ECHS_RS02520	COG3056	Lipoprotein
ECHS_RS02525	COG0271	Belongs to the BolA IbaG family
ECHS_RS02550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ECHS_RS02555	COG0776	regulation of translation
ECHS_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECHS_RS02565	COG1555	photosystem II stabilization
ECHS_RS02570	COG0824	Thioesterase
ECHS_RS02580	COG4533	DNA binding
ECHS_RS02590	COG1522	sequence-specific DNA binding
ECHS_RS02595	COG1132	(ABC) transporter
ECHS_RS02600	COG1132	(ABC) transporter
ECHS_RS02605	COG0347	Belongs to the P(II) protein family
ECHS_RS02610	COG0004	ammonium transporteR
ECHS_RS02615	COG1946	Acyl-CoA thioesterase
ECHS_RS02620	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ECHS_RS02625	COG3695	enzyme binding
ECHS_RS02630	COG5507	3-demethylubiquinone-9 3-methyltransferase
ECHS_RS02635	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECHS_RS02645	COG0110	maltose O-acetyltransferase activity
ECHS_RS02660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECHS_RS02665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECHS_RS02670	COG1309	transcriptional regulator
ECHS_RS02675	COG1196	nuclear chromosome segregation
ECHS_RS02675	COG3264	Mechanosensitive ion channel
ECHS_RS02690	COG3923	Primosomal replication protein n
ECHS_RS02695	COG2832	Protein of unknown function (DUF454)
ECHS_RS02705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECHS_RS02740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS02745	COG4651	solute:proton antiporter activity
ECHS_RS02745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECHS_RS02750	COG2223	nitrite transmembrane transporter activity
ECHS_RS02755	COG0737	Belongs to the 5'-nucleotidase family
ECHS_RS02760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECHS_RS02765	COG3735	TraB family
ECHS_RS02770	COG3093	addiction module antidote protein HigA
ECHS_RS02775	COG2217	Heavy metal translocating P-type atpase
ECHS_RS02785	COG0531	amino acid
ECHS_RS02790	COG0789	Transcriptional regulator
ECHS_RS02795	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECHS_RS02800	COG0330	HflC and HflK could
ECHS_RS02805	COG4619	ABC transporter
ECHS_RS02810	COG0390	transport system, permease component
ECHS_RS02815	COG3118	belongs to the thioredoxin family
ECHS_RS02820	COG0300	oxidoreductase activity
ECHS_RS02825	COG2755	lipolytic protein G-D-S-L family
ECHS_RS02830	COG4181	ATPase activity
ECHS_RS02835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ECHS_RS02845	COG0583	DNA-binding transcription factor activity
ECHS_RS02855	COG1414	Transcriptional regulator
ECHS_RS02860	COG3960	tartronate-semialdehyde synthase activity
ECHS_RS02865	COG3622	Belongs to the hyi family
ECHS_RS02870	COG2084	Dehydrogenase
ECHS_RS02875	COG1953	Uracil, thiamine, allantoin
ECHS_RS02885	COG2233	PERMEase
ECHS_RS02890	COG1929	Belongs to the glycerate kinase type-1 family
ECHS_RS02895	COG3257	ureidoglycine aminohydrolase activity
ECHS_RS02900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECHS_RS02905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECHS_RS02910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECHS_RS02915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECHS_RS02925	COG0549	Belongs to the carbamate kinase family
ECHS_RS02930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ECHS_RS02935	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ECHS_RS02945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECHS_RS02955	COG1988	membrane-bound metal-dependent
ECHS_RS02960	COG2501	S4 domain
ECHS_RS02970	COG3539	Fimbrial protein
ECHS_RS02975	COG3121	Chaperone
ECHS_RS02980	COG3188	usher protein
ECHS_RS02985	COG3539	Fimbrial protein
ECHS_RS02990	COG3539	Fimbrial protein
ECHS_RS02995	COG2197	response regulator
ECHS_RS03020	COG3501	Rhs element vgr protein
ECHS_RS03025	COG5002	protein histidine kinase activity
ECHS_RS03030	COG0745	RESPONSE REGULATOR receiver
ECHS_RS03035	COG1538	Outer membrane efflux protein
ECHS_RS03040	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECHS_RS03045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECHS_RS03050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECHS_RS03055	COG1113	amino acid transport
ECHS_RS03060	COG0668	transmembrane transport
ECHS_RS03065	COG0778	Nitroreductase
ECHS_RS03070	COG2315	Protein conserved in bacteria
ECHS_RS03095	COG3385	transposase activity
ECHS_RS03100	COG2977	Belongs to the P-Pant transferase superfamily
ECHS_RS03105	COG4771	TonB-dependent receptor
ECHS_RS03110	COG2382	esterase
ECHS_RS03115	COG3251	PFAM MbtH domain protein
ECHS_RS03120	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ECHS_RS03120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ECHS_RS03125	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECHS_RS03130	COG1120	ATPase activity
ECHS_RS03135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECHS_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECHS_RS03150	COG4592	Periplasmic binding protein
ECHS_RS03155	COG1169	isochorismate synthase
ECHS_RS03160	COG1021	2,3-dihydroxybenzoate-AMP ligase
ECHS_RS03165	COG3433	isochorismatase activity
ECHS_RS03165	COG1535	isochorismatase
ECHS_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS03175	COG2050	protein possibly involved in aromatic compounds catabolism
ECHS_RS03180	COG1966	Carbon starvation protein
ECHS_RS03185	COG2879	small protein
ECHS_RS03190	COG0371	Dehydrogenase
ECHS_RS03195	COG0436	Aminotransferase
ECHS_RS03200	COG1475	DNA binding
ECHS_RS03205	COG3969	phosphoadenosine phosphosulfate
ECHS_RS03210	COG0583	DNA-binding transcription factor activity
ECHS_RS03215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECHS_RS03220	COG0450	alkyl hydroperoxide reductase
ECHS_RS03225	COG3634	alkyl hydroperoxide reductase activity
ECHS_RS03230	COG0589	response to stress
ECHS_RS03235	COG1063	alcohol dehydrogenase
ECHS_RS03245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECHS_RS03250	COG3719	Belongs to the RNase T2 family
ECHS_RS03255	COG0471	metal ion transport
ECHS_RS03270	COG3051	citrate lyase alpha subunit
ECHS_RS03275	COG2301	Belongs to the HpcH HpaI aldolase family
ECHS_RS03285	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ECHS_RS03290	COG3290	protein histidine kinase activity
ECHS_RS03295	COG4565	transcriptional regulatory protein
ECHS_RS03300	COG3069	C4-dicarboxylate transmembrane transporter activity
ECHS_RS03320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECHS_RS03325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECHS_RS03335	COG0583	DNA-binding transcription factor activity
ECHS_RS03355	COG1686	Belongs to the peptidase S11 family
ECHS_RS03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECHS_RS03365	COG0772	Belongs to the SEDS family
ECHS_RS03370	COG0768	penicillin binding
ECHS_RS03380	COG0799	negative regulation of ribosome biogenesis
ECHS_RS03385	COG0406	alpha-ribazole phosphatase activity
ECHS_RS03395	COG1466	dna polymerase III delta subunit
ECHS_RS03410	COG2888	peptidyl-tyrosine sulfation
ECHS_RS03420	COG1126	abc transporter atp-binding protein
ECHS_RS03425	COG0765	amino acid transport
ECHS_RS03430	COG0765	amino acid transport
ECHS_RS03435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS03445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ECHS_RS03450	COG4535	Mg2 and Co2 transporter CorC
ECHS_RS03460	COG1702	phosphate starvation-inducible protein PhoH
ECHS_RS03470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECHS_RS03510	COG0367	asparagine synthase
ECHS_RS03515	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS03520	COG0647	UMP catabolic process
ECHS_RS03525	COG1846	Transcriptional regulator
ECHS_RS03525	COG1940	carbohydrate kinase activity
ECHS_RS03530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECHS_RS03540	COG2190	(PTS) system
ECHS_RS03540	COG1263	PTS System
ECHS_RS03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS03560	COG0735	belongs to the Fur family
ECHS_RS03575	COG0716	FMN binding
ECHS_RS03585	COG0596	Alpha beta hydrolase
ECHS_RS03590	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ECHS_RS03595	COG0033	Phosphoglucomutase
ECHS_RS03615	COG0745	RESPONSE REGULATOR receiver
ECHS_RS03620	COG2205	protein histidine kinase activity
ECHS_RS03650	COG3209	COG3209 Rhs family protein
ECHS_RS03660	COG3209	COG3209 Rhs family protein
ECHS_RS03670	COG5433	transposase activity
ECHS_RS03680	COG5433	transposase activity
ECHS_RS03685	COG3272	Protein of unknown function (DUF1722)
ECHS_RS03690	COG0415	Belongs to the DNA photolyase family
ECHS_RS03695	COG3104	oligopeptide transport
ECHS_RS03700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ECHS_RS03705	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ECHS_RS03710	COG1984	allophanate hydrolase subunit 2
ECHS_RS03725	COG3180	Ammonia monooxygenase
ECHS_RS03730	COG3539	Fimbrial protein
ECHS_RS03735	COG3121	Chaperone
ECHS_RS03740	COG3188	usher protein
ECHS_RS03745	COG3539	Fimbrial protein
ECHS_RS03750	COG0372	Belongs to the citrate synthase family
ECHS_RS03760	COG2009	succinate dehydrogenase
ECHS_RS03765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ECHS_RS03770	COG1053	succinate dehydrogenase
ECHS_RS03775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECHS_RS03785	COG0567	Dehydrogenase, E1 component
ECHS_RS03790	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECHS_RS03800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECHS_RS03805	COG2188	Transcriptional regulator
ECHS_RS03810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS03810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS03810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS03815	COG0383	alpha-mannosidase activity
ECHS_RS03825	COG0383	alpha-mannosidase activity
ECHS_RS03835	COG1271	oxidase subunit
ECHS_RS03840	COG1294	oxidase, subunit
ECHS_RS03845	COG4890	Cyd operon protein YbgT
ECHS_RS03850	COG3790	cyd operon protein YbgE
ECHS_RS03855	COG0824	Thioesterase
ECHS_RS03860	COG0811	peptide transport
ECHS_RS03865	COG0848	biopolymer transport protein
ECHS_RS03870	COG3064	Membrane
ECHS_RS03880	COG2885	chlorophyll binding
ECHS_RS03885	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ECHS_RS03930	COG3201	nicotinamide mononucleotide transporter
ECHS_RS03935	COG1230	cation diffusion facilitator family transporter
ECHS_RS03950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECHS_RS03960	COG2017	converts alpha-aldose to the beta-anomer
ECHS_RS03970	COG1085	galactose-1-phosphate uridylyltransferase
ECHS_RS03975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ECHS_RS03980	COG1119	ATPase activity
ECHS_RS03985	COG2005	Transcriptional regulator
ECHS_RS03985	COG3585	molybdate ion transport
ECHS_RS03995	COG0725	ABC transporter, periplasmic molybdate-binding protein
ECHS_RS04000	COG4149	molybdate abc transporter
ECHS_RS04005	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ECHS_RS04010	COG0561	phosphatase activity
ECHS_RS04020	COG0583	DNA-binding transcription factor activity
ECHS_RS04025	COG2828	Protein conserved in bacteria
ECHS_RS04030	COG0471	metal ion transport
ECHS_RS04035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECHS_RS04040	COG4677	pectinesterase activity
ECHS_RS04045	COG1881	PFAM PEBP family protein
ECHS_RS04050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ECHS_RS04065	COG2226	methyltransferase
ECHS_RS04070	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECHS_RS04080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ECHS_RS04095	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECHS_RS04105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ECHS_RS04110	COG0314	molybdopterin synthase activity
ECHS_RS04115	COG0670	Belongs to the BI1 family
ECHS_RS04120	COG0670	Belongs to the BI1 family
ECHS_RS04125	COG0392	lysyltransferase activity
ECHS_RS04130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECHS_RS04135	COG3568	Endonuclease Exonuclease Phosphatase
ECHS_RS04145	COG0842	Transport permease protein
ECHS_RS04150	COG0842	Transport permease protein
ECHS_RS04155	COG1131	(ABC) transporter
ECHS_RS04165	COG1309	transcriptional regulator
ECHS_RS04170	COG0513	Belongs to the DEAD box helicase family
ECHS_RS04180	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ECHS_RS04185	COG1199	ATP-dependent helicase activity
ECHS_RS04190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECHS_RS04195	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECHS_RS04205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECHS_RS04215	COG4774	siderophore transport
ECHS_RS04230	COG0668	transmembrane transport
ECHS_RS04235	COG1126	abc transporter atp-binding protein
ECHS_RS04240	COG0765	amino acid transport
ECHS_RS04245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS04260	COG5006	permease, DMT superfamily
ECHS_RS04265	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECHS_RS04270	COG2194	sulfuric ester hydrolase activity
ECHS_RS04280	COG1321	iron dependent repressor
ECHS_RS04285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECHS_RS04290	COG1376	ErfK ybiS ycfS ynhG family protein
ECHS_RS04295	COG0488	(ABC) transporter
ECHS_RS04300	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS04310	COG0561	phosphatase activity
ECHS_RS04315	COG1882	Formate acetyltransferase
ECHS_RS04320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECHS_RS04325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECHS_RS04330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECHS_RS04335	COG0303	'Molybdopterin
ECHS_RS04340	COG1446	asparaginase
ECHS_RS04350	COG0747	negative chemotaxis
ECHS_RS04365	COG2200	EAL domain
ECHS_RS04370	COG2199	diguanylate cyclase activity
ECHS_RS04395	COG2133	pyrroloquinoline quinone binding
ECHS_RS04400	COG0625	glutathione transferase activity
ECHS_RS04405	COG1686	Belongs to the peptidase S11 family
ECHS_RS04410	COG1349	DNA-binding transcription factor activity
ECHS_RS04415	COG0671	phosphoesterase, PA-phosphatase related
ECHS_RS04420	COG2814	Major facilitator Superfamily
ECHS_RS04430	COG0561	phosphatase activity
ECHS_RS04435	COG0738	Major facilitator superfamily
ECHS_RS04440	COG3226	Transcriptional regulator
ECHS_RS04450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ECHS_RS04480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECHS_RS04515	COG4695	Portal protein
ECHS_RS04600	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECHS_RS04660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECHS_RS04670	COG0778	Nitroreductase
ECHS_RS04690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECHS_RS04695	COG3842	ATPase activity
ECHS_RS04700	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECHS_RS04705	COG1177	transmembrane transport
ECHS_RS04720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS04725	COG4160	amino acid transport
ECHS_RS04730	COG4215	(ABC) transporter
ECHS_RS04735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS04740	COG1126	abc transporter atp-binding protein
ECHS_RS04755	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECHS_RS04760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECHS_RS04765	COG0702	epimerase
ECHS_RS04770	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ECHS_RS04775	COG0028	Belongs to the TPP enzyme family
ECHS_RS04780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECHS_RS04790	COG2431	L-lysine efflux transmembrane transporter activity
ECHS_RS04805	COG3593	DNA synthesis involved in DNA repair
ECHS_RS04810	COG2990	Protein conserved in bacteria
ECHS_RS04815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECHS_RS04820	COG1136	(ABC) transporter
ECHS_RS04820	COG0577	efflux transmembrane transporter activity
ECHS_RS04825	COG1278	Cold shock
ECHS_RS04835	COG0542	response to heat
ECHS_RS04855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ECHS_RS04860	COG4988	ABC transporter
ECHS_RS04865	COG0492	ferredoxin-NADP+ reductase activity
ECHS_RS04870	COG1522	sequence-specific DNA binding
ECHS_RS04875	COG1674	ftsk spoiiie
ECHS_RS04875	COG1178	ABC-type Fe3 transport system permease component
ECHS_RS04885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ECHS_RS04895	COG0243	molybdopterin cofactor binding
ECHS_RS04900	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS04905	COG3302	dmso reductase anchor subunit
ECHS_RS04910	COG1335	isochorismatase
ECHS_RS04920	COG0531	amino acid
ECHS_RS04925	COG0583	DNA-binding transcription factor activity
ECHS_RS04935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECHS_RS04940	COG1882	Formate acetyltransferase
ECHS_RS04945	COG2116	formate transmembrane transporter activity
ECHS_RS04950	COG1944	ATP diphosphatase activity
ECHS_RS04955	COG2323	membrane
ECHS_RS04970	COG0501	Belongs to the peptidase M48B family
ECHS_RS04980	COG0539	negative regulation of cytoplasmic translation
ECHS_RS04995	COG1132	(ABC) transporter
ECHS_RS05005	COG3214	Protein conserved in bacteria
ECHS_RS05020	COG3173	Aminoglycoside phosphotransferase
ECHS_RS05025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECHS_RS05030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECHS_RS05040	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ECHS_RS05050	COG2989	Protein conserved in bacteria
ECHS_RS05055	COG3108	Peptidase M15
ECHS_RS05060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECHS_RS05065	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS05070	COG1448	Aminotransferase
ECHS_RS05095	COG0308	aminopeptidase N
ECHS_RS05100	COG1116	anion transmembrane transporter activity
ECHS_RS05105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECHS_RS05115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECHS_RS05120	COG0431	NADPH-dependent FMN reductase
ECHS_RS05130	COG3121	Chaperone
ECHS_RS05135	COG3188	usher protein
ECHS_RS05140	COG3539	Fimbrial protein
ECHS_RS05145	COG3539	Fimbrial protein
ECHS_RS05150	COG3539	Fimbrial protein
ECHS_RS05155	COG3121	Chaperone
ECHS_RS05170	COG3217	Mosc domain protein beta barrel domain protein
ECHS_RS05170	COG0633	Ferredoxin
ECHS_RS05180	COG0488	(ABC) transporter
ECHS_RS05185	COG2995	paraquat-inducible protein a
ECHS_RS05190	COG3008	intermembrane lipid transfer
ECHS_RS05190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECHS_RS05195	COG3009	Protein conserved in bacteria
ECHS_RS05200	COG3130	regulation of translation
ECHS_RS05210	COG1067	ATP-dependent peptidase activity
ECHS_RS05220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECHS_RS05220	COG2885	chlorophyll binding
ECHS_RS05235	COG3070	regulator of competence-specific genes
ECHS_RS05240	COG1289	transmembrane transporter activity
ECHS_RS05245	COG3304	Inner membrane component domain
ECHS_RS05250	COG0210	DNA helicase
ECHS_RS05270	COG1832	CoA-binding protein
ECHS_RS05285	COG1254	Belongs to the acylphosphatase family
ECHS_RS05290	COG2920	part of a sulfur-relay system
ECHS_RS05295	COG0670	Belongs to the BI1 family
ECHS_RS05305	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECHS_RS05310	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECHS_RS05315	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ECHS_RS05320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECHS_RS05325	COG1999	signal sequence binding
ECHS_RS05330	COG1773	rubredoxin
ECHS_RS05335	COG1271	oxidase subunit
ECHS_RS05340	COG1294	oxidase, subunit
ECHS_RS05355	COG3206	protein involved in exopolysaccharide biosynthesis
ECHS_RS05355	COG0489	protein tyrosine kinase activity
ECHS_RS05360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECHS_RS05365	COG1596	polysaccharide export
ECHS_RS05390	COG1278	Cold shock
ECHS_RS05395	COG1278	Cold shock
ECHS_RS05410	COG0348	domain, Protein
ECHS_RS05415	COG0784	Response regulator, receiver
ECHS_RS05415	COG2198	Histidine kinase
ECHS_RS05415	COG2205	protein histidine kinase activity
ECHS_RS05420	COG1879	ABC-type sugar transport system periplasmic component
ECHS_RS05425	COG0745	RESPONSE REGULATOR receiver
ECHS_RS05430	COG3005	denitrification pathway
ECHS_RS05435	COG0243	molybdopterin cofactor binding
ECHS_RS05480	COG3729	General stress protein
ECHS_RS05485	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS05490	COG2233	PERMEase
ECHS_RS05525	COG1309	transcriptional regulator
ECHS_RS05530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECHS_RS05530	COG0506	proline dehydrogenase activity
ECHS_RS05530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECHS_RS05540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECHS_RS05555	COG2822	iron ion transport
ECHS_RS05560	COG2837	iron assimilation
ECHS_RS05570	COG1702	phosphate starvation-inducible protein PhoH
ECHS_RS05575	COG3658	cytochrome
ECHS_RS05580	COG1215	transferase activity, transferring glycosyl groups
ECHS_RS05585	COG1649	PFAM Uncharacterised BCR, COG1649
ECHS_RS05585	COG0726	polysaccharide deacetylase
ECHS_RS05590	COG0457	Tetratricopeptide repeat
ECHS_RS05600	COG0457	Tetratricopeptide repeat
ECHS_RS05605	COG3706	GGDEF domain
ECHS_RS05610	COG2801	Transposase and inactivated derivatives
ECHS_RS05615	COG2801	Transposase and inactivated derivatives
ECHS_RS05620	COG2801	Transposase and inactivated derivatives
ECHS_RS05660	COG3381	protein complex oligomerization
ECHS_RS05670	COG1462	curli production assembly transport component CsgG
ECHS_RS05685	COG2197	response regulator
ECHS_RS05720	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECHS_RS05725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECHS_RS05750	COG2943	transferase activity, transferring hexosyl groups
ECHS_RS05755	COG5645	(Lipo)protein
ECHS_RS05775	COG1560	Kdo2-lipid A biosynthetic process
ECHS_RS05785	COG2353	YceI-like domain
ECHS_RS05790	COG3038	cytochrome b561
ECHS_RS05825	COG2999	glutathione oxidoreductase activity
ECHS_RS05835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECHS_RS05845	COG0673	inositol 2-dehydrogenase activity
ECHS_RS05850	COG0728	peptidoglycan biosynthetic process
ECHS_RS05855	COG3418	PFAM FlgN family protein
ECHS_RS05860	COG2747	anti-sigma28 factor FlgM
ECHS_RS05865	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ECHS_RS05870	COG1815	bacterial-type flagellum-dependent cell motility
ECHS_RS05875	COG1558	bacterial-type flagellum-dependent cell motility
ECHS_RS05880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ECHS_RS05885	COG1749	Flagellar hook protein flgE
ECHS_RS05890	COG4787	bacterial-type flagellum-dependent cell motility
ECHS_RS05895	COG4786	Flagellar basal body rod
ECHS_RS05910	COG1705	Flagellar rod assembly protein muramidase FlgJ
ECHS_RS05910	COG3951	Flagellar rod assembly protein muramidase FlgJ
ECHS_RS05915	COG1256	bacterial-type flagellum assembly
ECHS_RS05920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECHS_RS05925	COG1530	ribonuclease E activity
ECHS_RS05935	COG0564	pseudouridine synthase activity
ECHS_RS05940	COG0424	maF-like protein
ECHS_RS05945	COG1399	metal-binding, possibly nucleic acid-binding protein
ECHS_RS05965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ECHS_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS05980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECHS_RS05985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECHS_RS05990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ECHS_RS06000	COG0470	DNA polymerase III
ECHS_RS06005	COG0084	hydrolase, TatD family'
ECHS_RS06010	COG1263	PTS System
ECHS_RS06010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS06015	COG4773	Receptor
ECHS_RS06020	COG0537	adenosine 5'-monophosphoramidase activity
ECHS_RS06025	COG5633	Lipoprotein
ECHS_RS06030	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ECHS_RS06050	COG1252	NADH dehydrogenase
ECHS_RS06055	COG3134	Outer membrane lipoprotein
ECHS_RS06060	COG1309	transcriptional regulator
ECHS_RS06070	COG1376	ErfK ybiS ycfS ynhG family protein
ECHS_RS06070	COG1388	LysM domain
ECHS_RS06075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ECHS_RS06080	COG4763	Acyl-transferase
ECHS_RS06085	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECHS_RS06090	COG1136	(ABC) transporter
ECHS_RS06095	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECHS_RS06105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ECHS_RS06110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECHS_RS06115	COG1177	transmembrane transport
ECHS_RS06140	COG2850	peptidyl-arginine hydroxylation
ECHS_RS06145	COG2205	protein histidine kinase activity
ECHS_RS06150	COG0745	RESPONSE REGULATOR receiver
ECHS_RS06155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECHS_RS06175	COG1187	pseudouridine synthase activity
ECHS_RS06180	COG0538	isocitrate dehydrogenase activity
ECHS_RS06195	COG5562	phage envelope protein
ECHS_RS06200	COG0789	Transcriptional regulator
ECHS_RS06205	COG2200	EAL domain
ECHS_RS06215	COG2801	Transposase and inactivated derivatives
ECHS_RS06220	COG2963	transposase activity
ECHS_RS06240	COG2200	EAL domain
ECHS_RS06285	COG2894	cell division
ECHS_RS06310	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECHS_RS06330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECHS_RS06335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ECHS_RS06340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ECHS_RS06355	COG2719	SpoVR family
ECHS_RS06365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECHS_RS06375	COG1619	proteins homologs of microcin C7 resistance protein MccF
ECHS_RS06385	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ECHS_RS06405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS06405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECHS_RS06405	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ECHS_RS06410	COG1461	Dihydroxyacetone kinase
ECHS_RS06415	COG2376	Dihydroxyacetone kinase
ECHS_RS06420	COG3284	Transcriptional regulator
ECHS_RS06425	COG3468	outer membrane autotransporter barrel domain protein
ECHS_RS06435	COG0012	GTP binding
ECHS_RS06450	COG0659	secondary active sulfate transmembrane transporter activity
ECHS_RS06455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ECHS_RS06480	COG2890	protein-(glutamine-N5) methyltransferase activity
ECHS_RS06485	COG3094	Invasion gene expression up-regulator, SirB
ECHS_RS06490	COG2912	Transglutaminase-like superfamily
ECHS_RS06515	COG0387	Pfam Sodium calcium exchanger
ECHS_RS06520	COG4572	Cation transport regulator
ECHS_RS06525	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ECHS_RS06530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECHS_RS06535	COG4932	domain protein
ECHS_RS06540	COG2197	response regulator
ECHS_RS06545	COG3850	Histidine kinase
ECHS_RS06555	COG2223	nitrite transmembrane transporter activity
ECHS_RS06560	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECHS_RS06565	COG1140	nitrate reductase beta subunit
ECHS_RS06570	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECHS_RS06575	COG2181	nitrate reductase activity
ECHS_RS06600	COG0788	formyltetrahydrofolate deformylase activity
ECHS_RS06610	COG1752	Esterase of the alpha-beta hydrolase superfamily
ECHS_RS06615	COG0745	RESPONSE REGULATOR receiver
ECHS_RS06620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ECHS_RS06630	COG1435	thymidine kinase activity
ECHS_RS06645	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS06645	COG1454	alcohol dehydrogenase
ECHS_RS06650	COG2095	MarC family integral membrane protein
ECHS_RS06655	COG4166	transmembrane transport
ECHS_RS06660	COG0601	transmembrane transport
ECHS_RS06665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECHS_RS06670	COG0444	Belongs to the ABC transporter superfamily
ECHS_RS06675	COG4608	Belongs to the ABC transporter superfamily
ECHS_RS06695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECHS_RS06700	COG2350	Protein conserved in bacteria
ECHS_RS06705	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ECHS_RS06710	COG1607	acyl-coa hydrolase
ECHS_RS06725	COG3047	cAMP biosynthetic process
ECHS_RS06730	COG3685	Protein conserved in bacteria
ECHS_RS06735	COG3685	Protein conserved in bacteria
ECHS_RS06740	COG3729	General stress protein
ECHS_RS06755	COG0134	indole-3-glycerol-phosphate synthase activity
ECHS_RS06755	COG0135	phosphoribosylanthranilate isomerase activity
ECHS_RS06760	COG0512	Glutamine amidotransferase of anthranilate synthase
ECHS_RS06760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECHS_RS06765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECHS_RS06770	COG0613	PHP domain protein
ECHS_RS06775	COG0009	L-threonylcarbamoyladenylate synthase
ECHS_RS06780	COG4907	membrane protein (DUF2207)
ECHS_RS06785	COG1187	pseudouridine synthase activity
ECHS_RS06790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ECHS_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS06805	COG0616	signal peptide processing
ECHS_RS06820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECHS_RS06825	COG0583	DNA-binding transcription factor activity
ECHS_RS06845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECHS_RS06855	COG0671	phosphoesterase, PA-phosphatase related
ECHS_RS06860	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ECHS_RS06865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ECHS_RS06875	COG0023	Translation Initiation Factor
ECHS_RS06885	COG1349	DNA-binding transcription factor activity
ECHS_RS06895	COG5001	Diguanylate cyclase
ECHS_RS06910	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECHS_RS06910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECHS_RS06915	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECHS_RS06920	COG2852	Protein conserved in bacteria
ECHS_RS06925	COG4172	Belongs to the ABC transporter superfamily
ECHS_RS06930	COG4172	Belongs to the ABC transporter superfamily
ECHS_RS06935	COG4171	peptide transport system, permease
ECHS_RS06940	COG4168	peptide transport system, permease
ECHS_RS06945	COG4166	transmembrane transport
ECHS_RS06960	COG0531	amino acid
ECHS_RS06965	COG0174	glutamine synthetase
ECHS_RS06970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ECHS_RS06975	COG1917	Cupin 2, conserved barrel domain protein
ECHS_RS06975	COG1396	sequence-specific DNA binding
ECHS_RS06980	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS06985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECHS_RS06990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECHS_RS06995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ECHS_RS07000	COG1842	Phage shock protein A
ECHS_RS07010	COG1983	PspC domain protein
ECHS_RS07020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECHS_RS07025	COG0366	Alpha amylase catalytic
ECHS_RS07030	COG1653	transport
ECHS_RS07035	COG1175	transmembrane transport
ECHS_RS07040	COG0395	ABC-type sugar transport system, permease component
ECHS_RS07045	COG1063	alcohol dehydrogenase
ECHS_RS07050	COG1082	Xylose isomerase domain protein TIM barrel
ECHS_RS07055	COG0673	inositol 2-dehydrogenase activity
ECHS_RS07060	COG1554	hydrolase, family 65, central catalytic
ECHS_RS07065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECHS_RS07070	COG3842	ATPase activity
ECHS_RS07080	COG1609	Transcriptional regulator
ECHS_RS07085	COG3106	COG3106 Predicted ATPase
ECHS_RS07095	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ECHS_RS07100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ECHS_RS07105	COG4948	Mandelate Racemase Muconate Lactonizing
ECHS_RS07110	COG2866	Carboxypeptidase
ECHS_RS07115	COG0702	epimerase
ECHS_RS07120	COG1073	alpha beta
ECHS_RS07125	COG0583	DNA-binding transcription factor activity
ECHS_RS07135	COG4166	transmembrane transport
ECHS_RS07140	COG0668	transmembrane transport
ECHS_RS07145	COG3182	Iron-regulated membrane protein
ECHS_RS07150	COG0589	response to stress
ECHS_RS07155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECHS_RS07160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECHS_RS07165	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ECHS_RS07175	COG1473	amidohydrolase
ECHS_RS07180	COG1473	amidohydrolase
ECHS_RS07185	COG0583	DNA-binding transcription factor activity
ECHS_RS07195	COG2840	Smr protein MutS2
ECHS_RS07200	COG3706	GGDEF domain
ECHS_RS07215	COG0513	Belongs to the DEAD box helicase family
ECHS_RS07225	COG0589	response to stress
ECHS_RS07230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECHS_RS07235	COG1013	pyruvate-flavodoxin oxidoreductase activity
ECHS_RS07235	COG0674	pyruvate-flavodoxin oxidoreductase activity
ECHS_RS07235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECHS_RS07235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ECHS_RS07240	COG3042	response to heat
ECHS_RS07245	COG3187	Heat shock protein
ECHS_RS07250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECHS_RS07255	COG2911	Protein conserved in bacteria
ECHS_RS07265	COG3784	Protein of unknown function (DUF1318)
ECHS_RS07270	COG2207	Transcriptional regulator
ECHS_RS07275	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS07280	COG3733	amine oxidase
ECHS_RS07285	COG2030	dehydratase
ECHS_RS07285	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS07290	COG3396	Phenylacetate-CoA oxygenase
ECHS_RS07295	COG3460	Phenylacetate-CoA oxygenase
ECHS_RS07300	COG3396	Phenylacetate-CoA oxygenase
ECHS_RS07305	COG2151	metal-sulfur cluster biosynthetic enzyme
ECHS_RS07310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECHS_RS07315	COG1024	Enoyl-CoA hydratase
ECHS_RS07320	COG1024	Enoyl-CoA hydratase
ECHS_RS07325	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECHS_RS07330	COG2050	protein possibly involved in aromatic compounds catabolism
ECHS_RS07335	COG0183	Belongs to the thiolase family
ECHS_RS07340	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ECHS_RS07345	COG3327	negative regulation of DNA-templated transcription, initiation
ECHS_RS07350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECHS_RS07360	COG0667	Aldo Keto reductase
ECHS_RS07370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECHS_RS07375	COG4589	Belongs to the CDS family
ECHS_RS07380	COG2267	carboxylic ester hydrolase activity
ECHS_RS07385	COG2453	phosphatase
ECHS_RS07385	COG0671	phosphoesterase, PA-phosphatase related
ECHS_RS07395	COG1643	Atp-dependent helicase
ECHS_RS07400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECHS_RS07405	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS07410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECHS_RS07415	COG3038	cytochrome b561
ECHS_RS07430	COG0840	transmembrane signaling receptor activity
ECHS_RS07435	COG0583	DNA-binding transcription factor activity
ECHS_RS07440	COG5383	Protein conserved in bacteria
ECHS_RS07455	COG2841	Protein conserved in bacteria
ECHS_RS07460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECHS_RS07465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECHS_RS07470	COG1275	C4-dicarboxylate transporter malic acid transport protein
ECHS_RS07475	COG0500	methyltransferase
ECHS_RS07500	COG0675	Transposase, IS605 OrfB family
ECHS_RS07505	COG3135	benzoate transporter
ECHS_RS07510	COG1396	sequence-specific DNA binding
ECHS_RS07515	COG0826	peptidase U32
ECHS_RS07525	COG1724	mRNA binding
ECHS_RS07530	COG1598	PFAM Uncharacterised protein family UPF0150
ECHS_RS07535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECHS_RS07540	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECHS_RS07545	COG3842	ATPase activity
ECHS_RS07550	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECHS_RS07555	COG1177	transmembrane transport
ECHS_RS07580	COG3238	Protein conserved in bacteria
ECHS_RS07585	COG1247	-acetyltransferase
ECHS_RS07590	COG2130	NADP-dependent
ECHS_RS07595	COG1802	Transcriptional regulator
ECHS_RS07600	COG4772	TonB-dependent receptor
ECHS_RS07605	COG3391	amine dehydrogenase activity
ECHS_RS07610	COG1113	amino acid transport
ECHS_RS07615	COG0625	glutathione transferase activity
ECHS_RS07625	COG5433	transposase activity
ECHS_RS07635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECHS_RS07640	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ECHS_RS07645	COG0384	phenazine biosynthesis protein PhzF
ECHS_RS07650	COG2181	nitrate reductase activity
ECHS_RS07655	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECHS_RS07660	COG1140	nitrate reductase beta subunit
ECHS_RS07665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECHS_RS07670	COG2223	nitrite transmembrane transporter activity
ECHS_RS07675	COG4886	Leucine-rich repeat (LRR) protein
ECHS_RS07680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECHS_RS07685	COG0697	spore germination
ECHS_RS07690	COG3383	formate dehydrogenase (NAD+) activity
ECHS_RS07690	COG0243	molybdopterin cofactor binding
ECHS_RS07695	COG0243	molybdopterin cofactor binding
ECHS_RS07695	COG3383	formate dehydrogenase (NAD+) activity
ECHS_RS07700	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS07705	COG2864	formate dehydrogenase
ECHS_RS07710	COG3093	addiction module antidote protein HigA
ECHS_RS07715	COG1064	alcohol dehydrogenase
ECHS_RS07735	COG1764	response to oxidative stress
ECHS_RS07740	COG4608	Belongs to the ABC transporter superfamily
ECHS_RS07745	COG0444	Belongs to the ABC transporter superfamily
ECHS_RS07750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECHS_RS07755	COG0601	transmembrane transport
ECHS_RS07760	COG0747	negative chemotaxis
ECHS_RS07765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ECHS_RS07770	COG2199	diguanylate cyclase activity
ECHS_RS07770	COG2202	Pas domain
ECHS_RS07770	COG2200	EAL domain
ECHS_RS07775	COG3706	GGDEF domain
ECHS_RS07780	COG1649	PFAM Uncharacterised BCR, COG1649
ECHS_RS07785	COG0531	amino acid
ECHS_RS07790	COG0076	glutamate decarboxylase activity
ECHS_RS07800	COG0612	Peptidase, M16
ECHS_RS07805	COG4771	TonB-dependent receptor
ECHS_RS07810	COG4178	(ABC) transporter
ECHS_RS07815	COG0641	radical SAM
ECHS_RS07820	COG3119	arylsulfatase activity
ECHS_RS07825	COG2207	Transcriptional regulator
ECHS_RS07835	COG0243	molybdopterin cofactor binding
ECHS_RS07840	COG3539	Fimbrial protein
ECHS_RS07845	COG3539	Fimbrial protein
ECHS_RS07850	COG3539	Fimbrial protein
ECHS_RS07855	COG3188	usher protein
ECHS_RS07860	COG4977	sequence-specific DNA binding
ECHS_RS07865	COG3550	peptidyl-serine autophosphorylation
ECHS_RS07870	COG1396	sequence-specific DNA binding
ECHS_RS07875	COG3210	domain, Protein
ECHS_RS07875	COG2911	Protein conserved in bacteria
ECHS_RS07925	COG3781	membrane
ECHS_RS07935	COG2199	diguanylate cyclase activity
ECHS_RS07945	COG2066	Belongs to the glutaminase family
ECHS_RS07950	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS07955	COG0583	DNA-binding transcription factor activity
ECHS_RS07975	COG1846	Transcriptional regulator
ECHS_RS07980	COG4977	sequence-specific DNA binding
ECHS_RS07990	COG2723	6-phospho-beta-galactosidase activity
ECHS_RS08000	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECHS_RS08005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECHS_RS08015	COG2188	Transcriptional regulator
ECHS_RS08020	COG0697	spore germination
ECHS_RS08025	COG2814	Major facilitator Superfamily
ECHS_RS08035	COG3706	GGDEF domain
ECHS_RS08040	COG3111	PFAM Bacterial OB fold (BOF) protein
ECHS_RS08045	COG1546	Belongs to the CinA family
ECHS_RS08050	COG0339	signal peptide processing
ECHS_RS08055	COG4221	oxidoreductase activity
ECHS_RS08060	COG1802	Transcriptional regulator
ECHS_RS08070	COG0246	Mannitol dehydrogenase
ECHS_RS08075	COG0477	Major facilitator Superfamily
ECHS_RS08090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECHS_RS08095	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECHS_RS08150	COG1278	Cold shock
ECHS_RS08160	COG3772	lysozyme
ECHS_RS08175	COG2207	Transcriptional regulator
ECHS_RS08180	COG3272	Protein of unknown function (DUF1722)
ECHS_RS08210	COG1063	alcohol dehydrogenase
ECHS_RS08215	COG4948	Mandelate Racemase Muconate Lactonizing
ECHS_RS08230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECHS_RS08245	COG0243	molybdopterin cofactor binding
ECHS_RS08250	COG0243	molybdopterin cofactor binding
ECHS_RS08255	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS08260	COG3302	dmso reductase anchor subunit
ECHS_RS08265	COG3381	protein complex oligomerization
ECHS_RS08275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECHS_RS08280	COG1940	carbohydrate kinase activity
ECHS_RS08285	COG0583	DNA-binding transcription factor activity
ECHS_RS08290	COG2814	Major facilitator Superfamily
ECHS_RS08305	COG3591	Belongs to the peptidase S1B family
ECHS_RS08320	COG0628	permease
ECHS_RS08325	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ECHS_RS08330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ECHS_RS08340	COG0531	amino acid
ECHS_RS08350	COG3136	membrane protein required for alginate biosynthesis
ECHS_RS08355	COG0745	RESPONSE REGULATOR receiver
ECHS_RS08360	COG2205	protein histidine kinase activity
ECHS_RS08370	COG0114	fumarate hydratase activity
ECHS_RS08375	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECHS_RS08375	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECHS_RS08380	COG1482	cell wall glycoprotein biosynthetic process
ECHS_RS08385	COG5339	Protein conserved in bacteria
ECHS_RS08400	COG3250	beta-galactosidase activity
ECHS_RS08405	COG1309	transcriptional regulator
ECHS_RS08410	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS08415	COG1609	Transcriptional regulator
ECHS_RS08420	COG1263	PTS System
ECHS_RS08420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS08425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECHS_RS08435	COG0673	inositol 2-dehydrogenase activity
ECHS_RS08475	COG4659	FMN binding
ECHS_RS08485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECHS_RS08495	COG3104	oligopeptide transport
ECHS_RS08500	COG0625	glutathione transferase activity
ECHS_RS08505	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ECHS_RS08520	COG3895	Periplasmic Protein
ECHS_RS08530	COG3133	Outer membrane lipoprotein
ECHS_RS08545	COG1566	PFAM secretion protein HlyD family protein
ECHS_RS08550	COG1289	transmembrane transporter activity
ECHS_RS08555	COG2032	superoxide dismutase activity
ECHS_RS08560	COG4989	oxidoreductase activity
ECHS_RS08565	COG3313	Fe-S protein
ECHS_RS08570	COG1309	transcriptional regulator
ECHS_RS08575	COG1902	pentaerythritol trinitrate reductase activity
ECHS_RS08580	COG0346	lactoylglutathione lyase activity
ECHS_RS08590	COG1201	RNA secondary structure unwinding
ECHS_RS08595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ECHS_RS08600	COG0791	NLP P60 protein
ECHS_RS08605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECHS_RS08610	COG2814	Major facilitator Superfamily
ECHS_RS08625	COG0583	DNA-binding transcription factor activity
ECHS_RS08630	COG2814	Major facilitator Superfamily
ECHS_RS08635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECHS_RS08640	COG0307	riboflavin synthase, alpha
ECHS_RS08650	COG3468	outer membrane autotransporter barrel domain protein
ECHS_RS08670	COG4529	Protein conserved in bacteria
ECHS_RS08680	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ECHS_RS08685	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS08695	COG2414	aldehyde ferredoxin oxidoreductase
ECHS_RS08700	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS08710	COG0469	pyruvate kinase activity
ECHS_RS08715	COG4238	major outer membrane lipoprotein
ECHS_RS08720	COG1376	ErfK ybiS ycfS ynhG family protein
ECHS_RS08735	COG0719	Fe-S assembly protein
ECHS_RS08740	COG0396	ATPase activity
ECHS_RS08745	COG0719	Fe-S assembly protein
ECHS_RS08750	COG0316	Belongs to the HesB IscA family
ECHS_RS08760	COG2050	protein possibly involved in aromatic compounds catabolism
ECHS_RS08765	COG0277	FAD linked oxidase domain protein
ECHS_RS08765	COG0247	lactate metabolic process
ECHS_RS08770	COG0628	permease
ECHS_RS08780	COG0738	Major facilitator superfamily
ECHS_RS08785	COG2271	Major facilitator Superfamily
ECHS_RS08800	COG4670	ketone body catabolic process
ECHS_RS08810	COG1960	acyl-CoA dehydrogenase activity
ECHS_RS08815	COG2207	Transcriptional regulator
ECHS_RS08815	COG1917	Cupin 2, conserved barrel domain protein
ECHS_RS08825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECHS_RS08825	COG0574	Belongs to the PEP-utilizing enzyme family
ECHS_RS08840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECHS_RS08845	COG4256	Hemin uptake protein
ECHS_RS08855	COG2200	EAL domain
ECHS_RS08860	COG0791	NLP P60 protein
ECHS_RS08870	COG0386	Belongs to the glutathione peroxidase family
ECHS_RS08885	COG0072	phenylalanine-tRNA ligase activity
ECHS_RS08885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECHS_RS08930	COG3137	Salt-induced outer membrane protein
ECHS_RS08935	COG1105	Belongs to the carbohydrate kinase PfkB family
ECHS_RS08945	COG3001	Fructosamine kinase
ECHS_RS08955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECHS_RS08960	COG1988	membrane-bound metal-dependent
ECHS_RS08965	COG1823	symporter activity
ECHS_RS08980	COG0753	catalase activity
ECHS_RS08985	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS08995	COG1486	melibiose metabolic process
ECHS_RS09000	COG1917	Cupin 2, conserved barrel domain protein
ECHS_RS09000	COG2169	Transcriptional regulator
ECHS_RS09005	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECHS_RS09010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECHS_RS09015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECHS_RS09020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECHS_RS09035	COG0322	excinuclease ABC activity
ECHS_RS09045	COG3678	ATP-independent chaperone mediated protein folding
ECHS_RS09075	COG0708	Exodeoxyribonuclease III
ECHS_RS09080	COG0398	Pfam SNARE associated Golgi protein
ECHS_RS09090	COG0398	Pfam SNARE associated Golgi protein
ECHS_RS09095	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECHS_RS09100	COG4134	Bacterial extracellular solute-binding protein
ECHS_RS09105	COG4135	transport system, permease component
ECHS_RS09110	COG4136	ATPase activity
ECHS_RS09115	COG2897	thiosulfate sulfurtransferase activity
ECHS_RS09120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECHS_RS09125	COG0494	nUDIX hydrolase
ECHS_RS09135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ECHS_RS09145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECHS_RS09160	COG0778	Nitroreductase
ECHS_RS09170	COG0616	signal peptide processing
ECHS_RS09175	COG0252	asparaginase activity
ECHS_RS09180	COG1335	isochorismatase
ECHS_RS09185	COG2814	Major facilitator Superfamily
ECHS_RS09190	COG1349	DNA-binding transcription factor activity
ECHS_RS09195	COG0667	Aldo Keto reductase
ECHS_RS09200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS09205	COG0191	fructose-bisphosphate aldolase activity
ECHS_RS09215	COG2271	Major facilitator Superfamily
ECHS_RS09220	COG1063	alcohol dehydrogenase
ECHS_RS09225	COG3139	Protein of unknown function (DUF1315)
ECHS_RS09235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECHS_RS09240	COG0676	glucose-6-phosphate 1-epimerase activity
ECHS_RS09245	COG0656	L-ascorbic acid biosynthetic process
ECHS_RS09250	COG3713	MltA-interacting MipA family protein
ECHS_RS09255	COG2766	serine protein kinase
ECHS_RS09265	COG2199	diguanylate cyclase activity
ECHS_RS09270	COG2199	diguanylate cyclase activity
ECHS_RS09275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECHS_RS09290	COG2207	Transcriptional regulator
ECHS_RS09295	COG2807	transmembrane transport
ECHS_RS09300	COG3189	MarR family transcriptional regulator
ECHS_RS09305	COG3042	response to heat
ECHS_RS09310	COG2203	Gaf domain
ECHS_RS09310	COG2199	diguanylate cyclase activity
ECHS_RS09320	COG2261	transglycosylase associated protein
ECHS_RS09330	COG3615	Tellurite resistance protein tehB
ECHS_RS09340	COG0583	DNA-binding transcription factor activity
ECHS_RS09345	COG0473	3-isopropylmalate dehydrogenase activity
ECHS_RS09350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECHS_RS09355	COG4638	Rieske (2fe-2S)
ECHS_RS09360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECHS_RS09365	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ECHS_RS09370	COG0318	PFAM AMP-dependent synthetase and ligase
ECHS_RS09375	COG3065	identical protein binding
ECHS_RS09380	COG1214	PFAM Peptidase M22, glycoprotease
ECHS_RS09385	COG1199	ATP-dependent helicase activity
ECHS_RS09390	COG0251	oxidation-reduction process
ECHS_RS09415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECHS_RS09425	COG1760	l-serine dehydratase
ECHS_RS09430	COG2200	EAL domain
ECHS_RS09435	COG1253	flavin adenine dinucleotide binding
ECHS_RS09445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS09445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS09450	COG3715	PTS system
ECHS_RS09455	COG3716	PTS system mannose fructose sorbose family IID component
ECHS_RS09475	COG2226	methyltransferase
ECHS_RS09510	COG1414	Transcriptional regulator
ECHS_RS09515	COG2814	Major facilitator Superfamily
ECHS_RS09525	COG0793	Belongs to the peptidase S41A family
ECHS_RS09535	COG1956	GAF domain-containing protein
ECHS_RS09540	COG2995	paraquat-inducible protein a
ECHS_RS09545	COG3008	intermembrane lipid transfer
ECHS_RS09565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECHS_RS09580	COG1276	copper resistance
ECHS_RS09585	COG2372	response to copper ion
ECHS_RS09595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECHS_RS09600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECHS_RS09605	COG1770	oligopeptidase
ECHS_RS09610	COG2979	Protein of unknown function (DUF533)
ECHS_RS09625	COG3141	response to X-ray
ECHS_RS09635	COG0800	Aldolase
ECHS_RS09640	COG0129	dihydroxy-acid dehydratase activity
ECHS_RS09645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ECHS_RS09655	COG1737	Transcriptional regulator
ECHS_RS09660	COG0469	pyruvate kinase activity
ECHS_RS09665	COG1560	Kdo2-lipid A biosynthetic process
ECHS_RS09670	COG0739	heme binding
ECHS_RS09675	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ECHS_RS09685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECHS_RS09710	COG0217	transcriptional regulatory protein
ECHS_RS09715	COG0494	nUDIX hydrolase
ECHS_RS09725	COG1335	isochorismatase
ECHS_RS09730	COG1801	Protein of unknown function DUF72
ECHS_RS09735	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ECHS_RS09750	COG0243	molybdopterin cofactor binding
ECHS_RS09755	COG3005	denitrification pathway
ECHS_RS09765	COG3102	Protein conserved in bacteria
ECHS_RS09775	COG3755	Protein conserved in bacteria
ECHS_RS09785	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECHS_RS09790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECHS_RS09795	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ECHS_RS09800	COG0745	RESPONSE REGULATOR receiver
ECHS_RS09810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ECHS_RS09815	COG0840	transmembrane signaling receptor activity
ECHS_RS09820	COG0840	transmembrane signaling receptor activity
ECHS_RS09825	COG0835	chemotaxis
ECHS_RS09830	COG2198	Histidine kinase
ECHS_RS09830	COG0643	Histidine kinase
ECHS_RS09835	COG1360	Flagellar Motor Protein
ECHS_RS09840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECHS_RS09855	COG2963	transposase activity
ECHS_RS09860	COG2801	Transposase and inactivated derivatives
ECHS_RS09865	COG0589	response to stress
ECHS_RS09875	COG1877	trehalose-phosphatase activity
ECHS_RS09880	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS09885	COG1129	ABC transporter
ECHS_RS09890	COG1879	ABC-type sugar transport system periplasmic component
ECHS_RS09895	COG1528	Iron-storage protein
ECHS_RS09915	COG1528	Iron-storage protein
ECHS_RS09925	COG0814	amino acid
ECHS_RS09930	COG3318	Belongs to the UPF0149 family
ECHS_RS09930	COG3012	SEC-C Motif Domain Protein
ECHS_RS09960	COG2197	response regulator
ECHS_RS09975	COG2197	response regulator
ECHS_RS09980	COG1126	abc transporter atp-binding protein
ECHS_RS09985	COG0765	amino acid transport
ECHS_RS09995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS10005	COG1191	sigma factor activity
ECHS_RS10010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECHS_RS10015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECHS_RS10020	COG1516	flagellar protein fliS
ECHS_RS10030	COG0366	Alpha amylase catalytic
ECHS_RS10040	COG2391	methyltransferase activity
ECHS_RS10045	COG0425	Belongs to the sulfur carrier protein TusA family
ECHS_RS10050	COG2135	peptidase activity
ECHS_RS10060	COG2207	Transcriptional regulator
ECHS_RS10065	COG1881	PFAM PEBP family protein
ECHS_RS10070	COG2076	Multidrug Resistance protein
ECHS_RS10085	COG1766	The M ring may be actively involved in energy transduction
ECHS_RS10090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECHS_RS10095	COG1317	bacterial-type flagellum organization
ECHS_RS10100	COG1157	protein secretion by the type III secretion system
ECHS_RS10105	COG2882	bacterial-type flagellum organization
ECHS_RS10110	COG3144	bacterial-type flagellum assembly
ECHS_RS10115	COG1580	Controls the rotational direction of flagella during chemotaxis
ECHS_RS10120	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECHS_RS10125	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECHS_RS10130	COG3190	flagellar
ECHS_RS10135	COG1338	Plays a role in the flagellum-specific transport system
ECHS_RS10140	COG1987	bacterial-type flagellum assembly
ECHS_RS10145	COG1684	flagellar biosynthetic protein fliR
ECHS_RS10150	COG2197	response regulator
ECHS_RS10180	COG5475	Uncharacterized small protein (DUF2158)
ECHS_RS10185	COG2354	Protein conserved in bacteria
ECHS_RS10190	COG0697	spore germination
ECHS_RS10195	COG3727	T/G mismatch-specific endonuclease activity
ECHS_RS10200	COG0270	DNA (cytosine-5-)-methyltransferase activity
ECHS_RS10205	COG1418	mRNA catabolic process
ECHS_RS10210	COG2963	transposase activity
ECHS_RS10215	COG2801	Transposase and inactivated derivatives
ECHS_RS10220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECHS_RS10235	COG2205	protein histidine kinase activity
ECHS_RS10240	COG0745	RESPONSE REGULATOR receiver
ECHS_RS10245	COG2351	hydroxyisourate hydrolase activity
ECHS_RS10260	COG3443	Belongs to the bacterial solute-binding protein 9 family
ECHS_RS10265	COG3038	cytochrome b561
ECHS_RS10405	COG2373	Large extracellular alpha-helical protein
ECHS_RS10405	COG4932	domain protein
ECHS_RS10405	COG1388	LysM domain
ECHS_RS10410	COG2373	Large extracellular alpha-helical protein
ECHS_RS10410	COG1388	LysM domain
ECHS_RS10410	COG4932	domain protein
ECHS_RS10415	COG1388	LysM domain
ECHS_RS10415	COG1470	cell adhesion involved in biofilm formation
ECHS_RS10420	COG1388	LysM domain
ECHS_RS10420	COG1470	cell adhesion involved in biofilm formation
ECHS_RS10425	COG1388	LysM domain
ECHS_RS10425	COG1470	cell adhesion involved in biofilm formation
ECHS_RS10435	COG0477	Major facilitator Superfamily
ECHS_RS10440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ECHS_RS10445	COG0217	transcriptional regulatory protein
ECHS_RS10455	COG0534	Mate efflux family protein
ECHS_RS10465	COG0583	DNA-binding transcription factor activity
ECHS_RS10470	COG0583	DNA-binding transcription factor activity
ECHS_RS10480	COG1376	ErfK ybiS ycfS ynhG family protein
ECHS_RS10495	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ECHS_RS10510	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ECHS_RS10515	COG0405	Gamma-glutamyltransferase
ECHS_RS10525	COG3436	PFAM IS66 Orf2 family protein
ECHS_RS10530	COG4372	Transposase
ECHS_RS10620	COG3468	outer membrane autotransporter barrel domain protein
ECHS_RS10655	COG4917	ethanolamine utilization protein
ECHS_RS10665	COG1289	transmembrane transporter activity
ECHS_RS10675	COG1686	Belongs to the peptidase S11 family
ECHS_RS10680	COG2925	Exonuclease
ECHS_RS10685	COG0425	Belongs to the sulfur carrier protein TusA family
ECHS_RS10690	COG2391	methyltransferase activity
ECHS_RS10695	COG0531	amino acid
ECHS_RS10700	COG0583	DNA-binding transcription factor activity
ECHS_RS10705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECHS_RS10710	COG4115	mRNA cleavage
ECHS_RS10715	COG2161	toxin-antitoxin pair type II binding
ECHS_RS10735	COG0131	Imidazoleglycerol-phosphate dehydratase
ECHS_RS10735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECHS_RS10740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ECHS_RS10755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ECHS_RS10755	COG0140	phosphoribosyl-ATP diphosphatase activity
ECHS_RS10765	COG0438	transferase activity, transferring glycosyl groups
ECHS_RS10830	COG1088	dTDP-glucose 4,6-dehydratase activity
ECHS_RS10840	COG2244	polysaccharide biosynthetic process
ECHS_RS10855	COG0463	Glycosyl transferase, family 2
ECHS_RS10915	COG1253	flavin adenine dinucleotide binding
ECHS_RS10920	COG2982	Protein involved in outer membrane biogenesis
ECHS_RS10930	COG0572	uridine kinase
ECHS_RS10940	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ECHS_RS10945	COG0443	Heat shock 70 kDa protein
ECHS_RS10950	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ECHS_RS10955	COG3779	Protein conserved in bacteria
ECHS_RS10960	COG0631	protein serine/threonine phosphatase activity
ECHS_RS10965	COG4245	von Willebrand factor, type A
ECHS_RS10990	COG2205	protein histidine kinase activity
ECHS_RS10995	COG0745	RESPONSE REGULATOR receiver
ECHS_RS11005	COG0826	peptidase U32
ECHS_RS11030	COG1063	alcohol dehydrogenase
ECHS_RS11035	COG3775	system Galactitol-specific IIC component
ECHS_RS11040	COG3414	Phosphotransferase system galactitol-specific IIB component
ECHS_RS11045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS11060	COG1830	Aldolase
ECHS_RS11065	COG2211	Major facilitator Superfamily
ECHS_RS11070	COG1397	ADP-ribosylglycohydrolase
ECHS_RS11075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS11080	COG2188	Transcriptional regulator
ECHS_RS11085	COG3757	hydrolase, family 25
ECHS_RS11090	COG0351	phosphomethylpyrimidine kinase
ECHS_RS11110	COG5455	response to cobalt ion
ECHS_RS11115	COG3539	Fimbrial protein
ECHS_RS11120	COG3188	usher protein
ECHS_RS11125	COG3121	Chaperone
ECHS_RS11130	COG3539	Fimbrial protein
ECHS_RS11145	COG0489	protein tyrosine kinase activity
ECHS_RS11155	COG3831	ATPase activity
ECHS_RS11160	COG3831	ATPase activity
ECHS_RS11170	COG0714	Associated with various cellular activities
ECHS_RS11175	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ECHS_RS11180	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ECHS_RS11185	COG4715	Zinc finger, swim domain protein
ECHS_RS11190	COG4808	Protein conserved in bacteria
ECHS_RS11195	COG4807	Protein conserved in bacteria
ECHS_RS11200	COG3279	Response regulator of the LytR AlgR family
ECHS_RS11205	COG3275	phosphorelay sensor kinase activity
ECHS_RS11210	COG0789	Transcriptional regulator
ECHS_RS11220	COG1174	glycine betaine transport
ECHS_RS11225	COG1125	glycine betaine transport
ECHS_RS11230	COG1174	glycine betaine transport
ECHS_RS11235	COG1732	Glycine betaine
ECHS_RS11240	COG1472	Belongs to the glycosyl hydrolase 3 family
ECHS_RS11245	COG0277	FAD linked oxidase domain protein
ECHS_RS11250	COG1686	Belongs to the peptidase S11 family
ECHS_RS11260	COG0586	Pfam SNARE associated Golgi protein
ECHS_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS11280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECHS_RS11290	COG1346	cytolysis
ECHS_RS11300	COG2949	membrane
ECHS_RS11310	COG0493	'glutamate synthase
ECHS_RS11315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ECHS_RS11315	COG0167	dihydroorotate dehydrogenase activity
ECHS_RS11320	COG4211	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS11325	COG1129	ABC transporter
ECHS_RS11330	COG1879	ABC-type sugar transport system periplasmic component
ECHS_RS11335	COG1609	Transcriptional regulator
ECHS_RS11345	COG2311	Membrane
ECHS_RS11365	COG4771	TonB-dependent receptor
ECHS_RS11370	COG0833	amino acid
ECHS_RS11375	COG0583	DNA-binding transcription factor activity
ECHS_RS11380	COG2855	membrane
ECHS_RS11390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS11390	COG1522	sequence-specific DNA binding
ECHS_RS11395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECHS_RS11405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECHS_RS11415	COG2313	pseudouridylate synthase activity
ECHS_RS11420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS11425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS11425	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ECHS_RS11425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS11430	COG1105	Belongs to the carbohydrate kinase PfkB family
ECHS_RS11435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS11435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS11440	COG2814	Major facilitator Superfamily
ECHS_RS11455	COG0246	Mannitol dehydrogenase
ECHS_RS11460	COG0523	cobalamin synthesis protein
ECHS_RS11465	COG0671	phosphoesterase, PA-phosphatase related
ECHS_RS11470	COG0791	NLP P60 protein
ECHS_RS11475	COG2200	EAL domain
ECHS_RS11480	COG4166	transmembrane transport
ECHS_RS11485	COG4174	ABC transporter (Permease)
ECHS_RS11490	COG4239	(ABC) transporter, permease
ECHS_RS11495	COG4172	Belongs to the ABC transporter superfamily
ECHS_RS11505	COG2814	Major facilitator Superfamily
ECHS_RS11510	COG1187	pseudouridine synthase activity
ECHS_RS11515	COG1061	Type III restriction enzyme res subunit
ECHS_RS11535	COG3083	sulfuric ester hydrolase activity
ECHS_RS11545	COG3468	outer membrane autotransporter barrel domain protein
ECHS_RS11555	COG2197	response regulator
ECHS_RS11560	COG3088	subunit of a heme lyase
ECHS_RS11560	COG4235	cytochrome complex assembly
ECHS_RS11565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECHS_RS11570	COG1138	Cytochrome C-type biogenesis protein
ECHS_RS11580	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECHS_RS11585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECHS_RS11590	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECHS_RS11595	COG4133	protoheme IX ABC transporter activity
ECHS_RS11600	COG3005	denitrification pathway
ECHS_RS11605	COG3043	anaerobic respiration
ECHS_RS11610	COG0348	domain, Protein
ECHS_RS11615	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS11625	COG3062	negative regulation of establishment of protein localization
ECHS_RS11630	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS11630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS11650	COG4615	Cyclic peptide transporter
ECHS_RS11655	COG3145	DNA-N1-methyladenine dioxygenase activity
ECHS_RS11660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECHS_RS11660	COG2169	Transcriptional regulator
ECHS_RS11665	COG1477	protein flavinylation
ECHS_RS11670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECHS_RS11685	COG2198	Histidine kinase
ECHS_RS11685	COG0642	Histidine kinase
ECHS_RS11690	COG2197	response regulator
ECHS_RS11695	COG2205	protein histidine kinase activity
ECHS_RS11695	COG0784	Response regulator, receiver
ECHS_RS11700	COG3852	Histidine kinase
ECHS_RS11705	COG2204	response regulator
ECHS_RS11710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ECHS_RS11715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ECHS_RS11720	COG2031	fatty acid transporter
ECHS_RS11725	COG0183	Belongs to the thiolase family
ECHS_RS11730	COG4676	Protein conserved in bacteria
ECHS_RS11735	COG5445	Predicted secreted protein (DUF2300)
ECHS_RS11740	COG2373	Large extracellular alpha-helical protein
ECHS_RS11745	COG3234	Protein of unknown function (DUF1175)
ECHS_RS11750	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ECHS_RS11755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECHS_RS11765	COG3468	outer membrane autotransporter barrel domain protein
ECHS_RS11775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECHS_RS11780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECHS_RS11785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECHS_RS11790	COG3642	lipopolysaccharide core region biosynthetic process
ECHS_RS11795	COG0583	DNA-binding transcription factor activity
ECHS_RS11800	COG0584	glycerophosphoryl diester phosphodiesterase
ECHS_RS11805	COG2271	Major facilitator Superfamily
ECHS_RS11810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECHS_RS11820	COG0247	lactate metabolic process
ECHS_RS11825	COG5464	transposase or invertase
ECHS_RS11835	COG2271	Major facilitator Superfamily
ECHS_RS11845	COG1414	Transcriptional regulator
ECHS_RS11910	COG0318	PFAM AMP-dependent synthetase and ligase
ECHS_RS11920	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ECHS_RS11935	COG1169	isochorismate synthase
ECHS_RS11940	COG4575	ribosome binding
ECHS_RS11945	COG2153	protein acetylation
ECHS_RS11955	COG5160	protein modification by small protein removal
ECHS_RS11970	COG2304	oxidoreductase activity
ECHS_RS11975	COG2234	aminopeptidase activity
ECHS_RS11995	COG0457	Tetratricopeptide repeat
ECHS_RS12005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECHS_RS12010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECHS_RS12020	COG0839	Belongs to the complex I subunit 6 family
ECHS_RS12035	COG1034	ATP synthesis coupled electron transport
ECHS_RS12040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ECHS_RS12045	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ECHS_RS12065	COG0583	DNA-binding transcription factor activity
ECHS_RS12070	COG0436	Aminotransferase
ECHS_RS12080	COG0471	metal ion transport
ECHS_RS12080	COG0490	domain, Protein
ECHS_RS12085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECHS_RS12105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECHS_RS12110	COG0280	phosphate acetyltransferase
ECHS_RS12110	COG0857	belongs to the CobB CobQ family
ECHS_RS12115	COG1288	antiporter activity
ECHS_RS12120	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ECHS_RS12125	COG0622	Phosphoesterase
ECHS_RS12130	COG0625	glutathione transferase activity
ECHS_RS12135	COG0625	glutathione transferase activity
ECHS_RS12140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECHS_RS12145	COG1090	epimerase
ECHS_RS12155	COG4598	ABC transporter
ECHS_RS12160	COG4160	amino acid transport
ECHS_RS12165	COG4215	(ABC) transporter
ECHS_RS12170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS12175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS12180	COG0163	prenyltransferase activity
ECHS_RS12185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ECHS_RS12190	COG1286	toxin biosynthetic process
ECHS_RS12195	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ECHS_RS12200	COG0285	dihydrofolate synthase activity
ECHS_RS12210	COG0586	Pfam SNARE associated Golgi protein
ECHS_RS12220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECHS_RS12235	COG2814	Major facilitator Superfamily
ECHS_RS12240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECHS_RS12255	COG3101	peptidyl-lysine hydroxylation
ECHS_RS12260	COG0730	response to heat
ECHS_RS12275	COG2890	protein-(glutamine-N5) methyltransferase activity
ECHS_RS12290	COG3539	Fimbrial protein
ECHS_RS12295	COG3539	Fimbrial protein
ECHS_RS12300	COG3539	Fimbrial protein
ECHS_RS12305	COG3121	Chaperone
ECHS_RS12310	COG3188	usher protein
ECHS_RS12315	COG3539	Fimbrial protein
ECHS_RS12320	COG2062	phosphohistidine phosphatase, SixA
ECHS_RS12335	COG3691	Protein conserved in bacteria
ECHS_RS12340	COG2067	long-chain fatty acid transport protein
ECHS_RS12350	COG2853	Lipoprotein
ECHS_RS12355	COG2116	formate transmembrane transporter activity
ECHS_RS12365	COG0583	DNA-binding transcription factor activity
ECHS_RS12370	COG2610	gluconate transmembrane transporter activity
ECHS_RS12380	COG0477	Major facilitator Superfamily
ECHS_RS12385	COG1566	PFAM secretion protein HlyD family protein
ECHS_RS12390	COG2197	response regulator
ECHS_RS12395	COG0784	Response regulator, receiver
ECHS_RS12395	COG2205	protein histidine kinase activity
ECHS_RS12395	COG2198	Histidine kinase
ECHS_RS12395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS12400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ECHS_RS12405	COG0679	Auxin Efflux Carrier
ECHS_RS12410	COG0028	Belongs to the TPP enzyme family
ECHS_RS12440	COG1560	Kdo2-lipid A biosynthetic process
ECHS_RS12445	COG0436	Aminotransferase
ECHS_RS12450	COG3275	phosphorelay sensor kinase activity
ECHS_RS12455	COG3279	Response regulator of the LytR AlgR family
ECHS_RS12460	COG2207	Transcriptional regulator
ECHS_RS12465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECHS_RS12465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS12465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS12470	COG1363	Peptidase, m42
ECHS_RS12475	COG0006	proline dipeptidase activity
ECHS_RS12480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS12485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS12515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECHS_RS12520	COG3385	transposase activity
ECHS_RS12525	COG2200	EAL domain
ECHS_RS12525	COG2199	diguanylate cyclase activity
ECHS_RS12540	COG3415	Transposase
ECHS_RS12545	COG3415	Transposase
ECHS_RS12580	COG0583	DNA-binding transcription factor activity
ECHS_RS12585	COG0385	Bile acid
ECHS_RS12590	COG3530	Putative quorum-sensing-regulated virulence factor
ECHS_RS12610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECHS_RS12615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS12620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECHS_RS12625	COG2190	(PTS) system
ECHS_RS12640	COG4884	unkown
ECHS_RS12640	COG3831	ATPase activity
ECHS_RS12645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECHS_RS12650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ECHS_RS12655	COG4208	sulfate ABC transporter
ECHS_RS12660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ECHS_RS12665	COG4150	thiosulfate binding
ECHS_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS12685	COG1263	PTS System
ECHS_RS12685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS12690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECHS_RS12695	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS12700	COG2837	iron assimilation
ECHS_RS12720	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECHS_RS12730	COG2207	Transcriptional regulator
ECHS_RS12735	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECHS_RS12740	COG4816	utilization protein
ECHS_RS12750	COG4303	Ethanolamine ammonia lyase large subunit
ECHS_RS12755	COG4819	ethanolamine utilization protein
ECHS_RS12760	COG3192	ethanolamine utilization protein
ECHS_RS12765	COG1454	alcohol dehydrogenase
ECHS_RS12770	COG4820	ethanolamine utilization protein (EutJ)
ECHS_RS12775	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS12780	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ECHS_RS12785	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECHS_RS12790	COG0280	phosphate acetyltransferase
ECHS_RS12795	COG4812	Cobalamin adenosyltransferase
ECHS_RS12800	COG4766	ethanolamine catabolic process
ECHS_RS12805	COG4917	ethanolamine utilization protein
ECHS_RS12810	COG4810	utilization protein
ECHS_RS12815	COG0281	malic enzyme
ECHS_RS12815	COG0280	phosphate acetyltransferase
ECHS_RS12820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECHS_RS12825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECHS_RS12830	COG5342	invasion associated locus B
ECHS_RS12840	COG0493	'glutamate synthase
ECHS_RS12840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS12845	COG3850	Histidine kinase
ECHS_RS12850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECHS_RS12860	COG1393	Belongs to the ArsC family
ECHS_RS12875	COG0400	carboxylic ester hydrolase activity
ECHS_RS12885	COG2321	neutral zinc metallopeptidase
ECHS_RS12900	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ECHS_RS12910	COG2716	regulation of RNA biosynthetic process
ECHS_RS12915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ECHS_RS12920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS12925	COG0651	ATP synthesis coupled electron transport
ECHS_RS12930	COG0651	ATP synthesis coupled electron transport
ECHS_RS12935	COG0650	Formate hydrogenlyase subunit 4
ECHS_RS12945	COG4237	Hydrogenase 4 membrane
ECHS_RS12950	COG0651	ATP synthesis coupled electron transport
ECHS_RS12955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECHS_RS12955	COG3261	NADH dehydrogenase
ECHS_RS12960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECHS_RS12965	COG3260	NADH ubiquinone oxidoreductase 20
ECHS_RS12975	COG3604	Transcriptional regulator
ECHS_RS12980	COG2116	formate transmembrane transporter activity
ECHS_RS12985	COG0628	permease
ECHS_RS12990	COG4783	chaperone-mediated protein folding
ECHS_RS12995	COG1393	Belongs to the ArsC family
ECHS_RS13005	COG2233	PERMEase
ECHS_RS13020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ECHS_RS13025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ECHS_RS13030	COG0248	Ppx GppA phosphatase
ECHS_RS13050	COG3133	Outer membrane lipoprotein
ECHS_RS13060	COG3093	addiction module antidote protein HigA
ECHS_RS13070	COG3093	addiction module antidote protein HigA
ECHS_RS13075	COG3846	protein secretion by the type IV secretion system
ECHS_RS13115	COG0582	viral genome integration into host DNA
ECHS_RS13125	COG0516	GMP reductase activity
ECHS_RS13125	COG0517	IMP dehydrogenase activity
ECHS_RS13135	COG1645	bacterial-type flagellum-dependent swarming motility
ECHS_RS13150	COG2976	Protein conserved in bacteria
ECHS_RS13180	COG4953	penicillin-binding protein 1C
ECHS_RS13185	COG2373	Large extracellular alpha-helical protein
ECHS_RS13190	COG2897	thiosulfate sulfurtransferase activity
ECHS_RS13205	COG2975	iron-sulfur cluster assembly
ECHS_RS13210	COG0633	Ferredoxin
ECHS_RS13230	COG0822	iron-sulfur transferase activity
ECHS_RS13250	COG0483	inositol monophosphate 1-phosphatase activity
ECHS_RS13255	COG1073	alpha beta
ECHS_RS13260	COG3711	transcriptional antiterminator
ECHS_RS13265	COG2814	Major facilitator Superfamily
ECHS_RS13270	COG0583	DNA-binding transcription factor activity
ECHS_RS13300	COG2259	Doxx family
ECHS_RS13305	COG2017	converts alpha-aldose to the beta-anomer
ECHS_RS13310	COG1063	alcohol dehydrogenase
ECHS_RS13315	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS13320	COG1129	ABC transporter
ECHS_RS13325	COG1879	ABC-type sugar transport system periplasmic component
ECHS_RS13335	COG0457	Tetratricopeptide repeat
ECHS_RS13340	COG1940	carbohydrate kinase activity
ECHS_RS13350	COG1017	nitric oxide dioxygenase activity
ECHS_RS13350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECHS_RS13355	COG0347	Belongs to the P(II) protein family
ECHS_RS13360	COG2204	response regulator
ECHS_RS13365	COG3170	Tfp pilus assembly protein FimV
ECHS_RS13370	COG2205	protein histidine kinase activity
ECHS_RS13375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ECHS_RS13375	COG0047	phosphoribosylformylglycinamidine synthase activity
ECHS_RS13390	COG0560	Phosphoserine phosphatase
ECHS_RS13395	COG1737	Transcriptional regulator
ECHS_RS13400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS13425	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ECHS_RS13445	COG0681	Belongs to the peptidase S26 family
ECHS_RS13455	COG3086	response to oxidative stress
ECHS_RS13460	COG3026	antisigma factor binding
ECHS_RS13465	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ECHS_RS13470	COG1595	DNA-templated transcription, initiation
ECHS_RS13480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECHS_RS13490	COG0513	Belongs to the DEAD box helicase family
ECHS_RS13495	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS13500	COG0583	DNA-binding transcription factor activity
ECHS_RS13520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECHS_RS13530	COG3118	belongs to the thioredoxin family
ECHS_RS13535	COG3148	PFAM DTW domain containing protein
ECHS_RS13540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECHS_RS13540	COG1042	CoA-binding domain protein
ECHS_RS13540	COG0045	succinate-CoA ligase (ADP-forming) activity
ECHS_RS13545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECHS_RS13550	COG5544	Lipoprotein
ECHS_RS13555	COG0477	Major facilitator Superfamily
ECHS_RS13580	COG0542	response to heat
ECHS_RS13590	COG0564	pseudouridine synthase activity
ECHS_RS13595	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECHS_RS13605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECHS_RS13610	COG0077	Prephenate dehydratase
ECHS_RS13610	COG1605	Chorismate mutase
ECHS_RS13615	COG0287	Prephenate dehydrogenase
ECHS_RS13615	COG1605	Chorismate mutase
ECHS_RS13620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECHS_RS13640	COG2199	diguanylate cyclase activity
ECHS_RS13645	COG2885	chlorophyll binding
ECHS_RS13670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECHS_RS13675	COG4137	Cytochrome C assembly protein
ECHS_RS13680	COG4536	flavin adenine dinucleotide binding
ECHS_RS13700	COG0497	DNA recombination
ECHS_RS13705	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECHS_RS13715	COG2867	negative regulation of translational initiation
ECHS_RS13750	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECHS_RS13765	COG2801	Transposase and inactivated derivatives
ECHS_RS13770	COG2963	transposase activity
ECHS_RS13780	COG0366	Alpha amylase catalytic
ECHS_RS13790	COG0579	oxidoreductase
ECHS_RS13795	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS13800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECHS_RS13805	COG1113	amino acid transport
ECHS_RS13810	COG1802	Transcriptional regulator
ECHS_RS13815	COG1652	LysM domain
ECHS_RS13820	COG0401	homolog of Blt101
ECHS_RS13825	COG0640	Transcriptional regulator
ECHS_RS13830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECHS_RS13835	COG2916	Histone family protein nucleoid-structuring protein H-NS
ECHS_RS13850	COG4575	ribosome binding
ECHS_RS13855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECHS_RS13865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECHS_RS13870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECHS_RS13875	COG4175	Glycine betaine
ECHS_RS13880	COG4176	ABC-type proline glycine betaine transport system permease component
ECHS_RS13885	COG2113	Glycine betaine
ECHS_RS13890	COG2814	Major facilitator Superfamily
ECHS_RS13895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ECHS_RS13905	COG1846	Transcriptional regulator
ECHS_RS13910	COG1566	PFAM secretion protein HlyD family protein
ECHS_RS13915	COG2814	Major facilitator Superfamily
ECHS_RS13930	COG1238	metal cluster binding
ECHS_RS13935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECHS_RS13965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ECHS_RS13990	COG1546	Belongs to the CinA family
ECHS_RS13995	COG2951	lytic endotransglycosylase activity
ECHS_RS14000	COG3730	PTS system glucitol sorbitol-specific
ECHS_RS14005	COG3732	PTS system glucitol sorbitol-specific
ECHS_RS14015	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS14020	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS14025	COG1349	DNA-binding transcription factor activity
ECHS_RS14030	COG0517	IMP dehydrogenase activity
ECHS_RS14030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECHS_RS14050	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ECHS_RS14055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS14060	COG1609	Transcriptional regulator
ECHS_RS14065	COG1263	PTS System
ECHS_RS14065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS14070	COG2723	6-phospho-beta-galactosidase activity
ECHS_RS14075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECHS_RS14085	COG3260	NADH ubiquinone oxidoreductase 20
ECHS_RS14090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECHS_RS14095	COG3261	NADH dehydrogenase
ECHS_RS14095	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECHS_RS14100	COG0650	Formate hydrogenlyase subunit 4
ECHS_RS14105	COG0651	ATP synthesis coupled electron transport
ECHS_RS14110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS14125	COG0375	protein maturation
ECHS_RS14130	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ECHS_RS14135	COG0298	carbon dioxide binding
ECHS_RS14140	COG0409	Hydrogenase expression formation protein
ECHS_RS14145	COG0309	Hydrogenase expression formation protein (HypE)
ECHS_RS14150	COG3604	Transcriptional regulator
ECHS_RS14165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECHS_RS14170	COG1349	DNA-binding transcription factor activity
ECHS_RS14175	COG2084	Dehydrogenase
ECHS_RS14180	COG3395	kinase activity
ECHS_RS14185	COG0235	Class ii aldolase
ECHS_RS14190	COG3622	Belongs to the hyi family
ECHS_RS14195	COG2610	gluconate transmembrane transporter activity
ECHS_RS14200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECHS_RS14205	COG1388	LysM domain
ECHS_RS14205	COG4942	peptidase
ECHS_RS14260	COG2234	aminopeptidase activity
ECHS_RS14265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECHS_RS14270	COG1518	maintenance of DNA repeat elements
ECHS_RS14285	COG1857	crispr-associated protein
ECHS_RS14300	COG1203	CRISPR-associated helicase, Cas3
ECHS_RS14320	COG0720	synthase
ECHS_RS14325	COG0644	oxidoreductase
ECHS_RS14330	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECHS_RS14335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ECHS_RS14340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ECHS_RS14345	COG2086	electron transfer activity
ECHS_RS14350	COG0477	Major facilitator Superfamily
ECHS_RS14355	COG0277	FAD linked oxidase domain protein
ECHS_RS14360	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS14365	COG2223	nitrite transmembrane transporter activity
ECHS_RS14370	COG1070	Carbohydrate kinase
ECHS_RS14375	COG0602	queuosine metabolic process
ECHS_RS14385	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECHS_RS14410	COG3956	TIGRFAM MazG family protein
ECHS_RS14415	COG2337	Toxic component of a toxin-antitoxin (TA) module
ECHS_RS14420	COG2336	PFAM SpoVT AbrB
ECHS_RS14425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECHS_RS14430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECHS_RS14435	COG3437	response regulator, receiver
ECHS_RS14435	COG4999	Histidine kinase
ECHS_RS14435	COG2205	protein histidine kinase activity
ECHS_RS14435	COG3850	Histidine kinase
ECHS_RS14440	COG4948	Mandelate Racemase Muconate Lactonizing
ECHS_RS14445	COG4948	Mandelate Racemase Muconate Lactonizing
ECHS_RS14450	COG2271	Major facilitator Superfamily
ECHS_RS14455	COG0716	FMN binding
ECHS_RS14460	COG0564	pseudouridine synthase activity
ECHS_RS14465	COG3098	single-species biofilm formation
ECHS_RS14485	COG1611	Belongs to the LOG family
ECHS_RS14490	COG0814	amino acid
ECHS_RS14495	COG1760	l-serine dehydratase
ECHS_RS14505	COG1454	alcohol dehydrogenase
ECHS_RS14510	COG0235	Class ii aldolase
ECHS_RS14515	COG0738	Major facilitator superfamily
ECHS_RS14525	COG1070	Carbohydrate kinase
ECHS_RS14535	COG1349	DNA-binding transcription factor activity
ECHS_RS14545	COG2363	Small membrane protein
ECHS_RS14550	COG0583	DNA-binding transcription factor activity
ECHS_RS14560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECHS_RS14565	COG2166	iron-sulfur cluster assembly
ECHS_RS14570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ECHS_RS14575	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ECHS_RS14600	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECHS_RS14605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ECHS_RS14605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ECHS_RS14610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ECHS_RS14615	COG1074	ATP-dependent DNA helicase activity
ECHS_RS14620	COG1025	Belongs to the peptidase M16 family
ECHS_RS14625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ECHS_RS14630	COG4967	type IV pilus modification protein PilV
ECHS_RS14640	COG4795	General secretion pathway protein
ECHS_RS14645	COG2165	general secretion pathway protein
ECHS_RS14660	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ECHS_RS14685	COG0861	Integral membrane protein TerC family
ECHS_RS14695	COG0667	Aldo Keto reductase
ECHS_RS14710	COG1609	Transcriptional regulator
ECHS_RS14720	COG0583	DNA-binding transcription factor activity
ECHS_RS14725	COG1794	racemase activity, acting on amino acids and derivatives
ECHS_RS14730	COG2814	Major facilitator Superfamily
ECHS_RS14735	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS14745	COG0183	Belongs to the thiolase family
ECHS_RS14750	COG0814	amino acid
ECHS_RS14755	COG2771	luxR family
ECHS_RS14760	COG3710	Transcriptional regulator
ECHS_RS14790	COG0457	Tetratricopeptide repeat
ECHS_RS14795	COG3710	Transcriptional regulator
ECHS_RS14795	COG0457	Tetratricopeptide repeat
ECHS_RS14810	COG2197	response regulator
ECHS_RS14900	COG2801	Transposase and inactivated derivatives
ECHS_RS14905	COG2963	transposase activity
ECHS_RS14910	COG3387	PFAM Glycoside hydrolase 15-related
ECHS_RS14920	COG4942	peptidase
ECHS_RS14925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECHS_RS14930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECHS_RS14935	COG2080	2 iron, 2 sulfur cluster binding
ECHS_RS14940	COG3829	transcription factor binding
ECHS_RS14945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECHS_RS14950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECHS_RS14955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECHS_RS14965	COG0549	Belongs to the carbamate kinase family
ECHS_RS14970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ECHS_RS14970	COG3608	succinylglutamate desuccinylase aspartoacylase
ECHS_RS14975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECHS_RS14980	COG2068	MobA-Related Protein
ECHS_RS14985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS14985	COG0493	'glutamate synthase
ECHS_RS14990	COG0402	S-adenosylhomocysteine deaminase activity
ECHS_RS14995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECHS_RS15000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECHS_RS15000	COG2080	2 iron, 2 sulfur cluster binding
ECHS_RS15005	COG2233	PERMEase
ECHS_RS15010	COG0402	S-adenosylhomocysteine deaminase activity
ECHS_RS15015	COG2252	PERMEase
ECHS_RS15020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS15025	COG0493	'glutamate synthase
ECHS_RS15025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS15035	COG2233	PERMEase
ECHS_RS15050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECHS_RS15060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ECHS_RS15065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECHS_RS15070	COG4974	Belongs to the 'phage' integrase family
ECHS_RS15075	COG0716	FMN binding
ECHS_RS15085	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ECHS_RS15095	COG1272	protein, Hemolysin III
ECHS_RS15105	COG2723	6-phospho-beta-galactosidase activity
ECHS_RS15110	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS15130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECHS_RS15135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECHS_RS15140	COG0006	proline dipeptidase activity
ECHS_RS15155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ECHS_RS15160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECHS_RS15180	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECHS_RS15180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECHS_RS15185	COG1703	isobutyryl-CoA mutase activity
ECHS_RS15190	COG1024	Enoyl-CoA hydratase
ECHS_RS15195	COG0427	acetyl-CoA hydrolase
ECHS_RS15200	COG0583	DNA-binding transcription factor activity
ECHS_RS15205	COG2968	Membrane
ECHS_RS15210	COG1279	arginine transmembrane transporter activity
ECHS_RS15215	COG0668	transmembrane transport
ECHS_RS15220	COG0191	fructose-bisphosphate aldolase activity
ECHS_RS15235	COG1072	(Pantothenic acid kinase))
ECHS_RS15240	COG3722	fumarate hydratase activity
ECHS_RS15245	COG1494	fructose-1,6-bisphosphatase
ECHS_RS15250	COG1063	alcohol dehydrogenase
ECHS_RS15255	COG2213	PTS system mannitol-specific
ECHS_RS15265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECHS_RS15270	COG0501	Belongs to the peptidase M48B family
ECHS_RS15280	COG1166	arginine decarboxylase activity
ECHS_RS15305	COG2814	Major facilitator Superfamily
ECHS_RS15315	COG2356	endonuclease I
ECHS_RS15320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ECHS_RS15325	COG0189	ligase activity
ECHS_RS15340	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS15345	COG2805	Type II/IV secretion system protein
ECHS_RS15350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ECHS_RS15355	COG0762	integral membrane protein
ECHS_RS15370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECHS_RS15380	COG0252	asparaginase activity
ECHS_RS15395	COG3171	Protein conserved in bacteria
ECHS_RS15405	COG1194	a g-specific adenine glycosylase
ECHS_RS15420	COG2211	Major facilitator Superfamily
ECHS_RS15425	COG1982	Orn Lys Arg decarboxylase major
ECHS_RS15430	COG1811	Na channel or pump
ECHS_RS15440	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECHS_RS15470	COG2165	general secretion pathway protein
ECHS_RS15475	COG1459	type II secretion system
ECHS_RS15480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECHS_RS15520	COG1620	l-lactate permease
ECHS_RS15525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECHS_RS15530	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ECHS_RS15535	COG0247	lactate metabolic process
ECHS_RS15540	COG0277	FAD linked oxidase domain protein
ECHS_RS15545	COG0277	FAD linked oxidase domain protein
ECHS_RS15550	COG2186	Transcriptional regulator
ECHS_RS15555	COG0456	acetyltransferase
ECHS_RS15560	COG0318	PFAM AMP-dependent synthetase and ligase
ECHS_RS15570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECHS_RS15575	COG0156	8-amino-7-oxononanoate synthase activity
ECHS_RS15585	COG0795	lipopolysaccharide-transporting ATPase activity
ECHS_RS15590	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECHS_RS15600	COG2244	polysaccharide biosynthetic process
ECHS_RS15605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECHS_RS15610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECHS_RS15615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECHS_RS15620	COG0306	phosphate transporter
ECHS_RS15625	COG0754	glutathionylspermidine amidase activity
ECHS_RS15630	COG0625	glutathione transferase activity
ECHS_RS15635	COG0298	carbon dioxide binding
ECHS_RS15645	COG1773	rubredoxin
ECHS_RS15650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECHS_RS15655	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECHS_RS15660	COG5557	Pfam Polysulphide reductase, NrfD
ECHS_RS15665	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS15670	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECHS_RS15690	COG0667	Aldo Keto reductase
ECHS_RS15700	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS15705	COG0848	biopolymer transport protein
ECHS_RS15710	COG0811	peptide transport
ECHS_RS15720	COG0626	cystathionine gamma-synthase activity
ECHS_RS15725	COG0586	Pfam SNARE associated Golgi protein
ECHS_RS15730	COG2207	Transcriptional regulator
ECHS_RS15740	COG1979	alcohol dehydrogenase
ECHS_RS15745	COG0656	L-ascorbic acid biosynthetic process
ECHS_RS15755	COG4238	major outer membrane lipoprotein
ECHS_RS15760	COG1032	radical SAM domain protein
ECHS_RS15765	COG2132	Multicopper oxidase
ECHS_RS15770	COG0204	Acyl-transferase
ECHS_RS15775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECHS_RS15780	COG4166	transmembrane transport
ECHS_RS15785	COG2944	sequence-specific DNA binding
ECHS_RS15795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECHS_RS15800	COG3111	PFAM Bacterial OB fold (BOF) protein
ECHS_RS15805	COG0745	RESPONSE REGULATOR receiver
ECHS_RS15810	COG0642	Histidine kinase
ECHS_RS15820	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECHS_RS15825	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ECHS_RS15830	COG0187	DNA topoisomerase II activity
ECHS_RS15835	COG3150	esterase
ECHS_RS15840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ECHS_RS15845	COG3151	Protein conserved in bacteria
ECHS_RS15850	COG0494	nUDIX hydrolase
ECHS_RS15855	COG1538	Outer membrane efflux protein
ECHS_RS15870	COG0754	glutathionylspermidine amidase activity
ECHS_RS15875	COG3384	dioxygenase
ECHS_RS15895	COG2960	long-chain fatty acid transporting porin activity
ECHS_RS15900	COG3539	Fimbrial protein
ECHS_RS15905	COG3188	usher protein
ECHS_RS15910	COG3121	Chaperone
ECHS_RS15915	COG3539	Fimbrial protein
ECHS_RS15925	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECHS_RS15955	COG3025	triphosphatase activity
ECHS_RS15965	COG4991	sh3 domain protein
ECHS_RS15985	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECHS_RS15995	COG0583	DNA-binding transcription factor activity
ECHS_RS16005	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECHS_RS16010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECHS_RS16015	COG0471	metal ion transport
ECHS_RS16025	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ECHS_RS16030	COG0358	DNA primase activity
ECHS_RS16035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECHS_RS16050	COG2375	cellular response to nickel ion
ECHS_RS16055	COG1695	Transcriptional regulator
ECHS_RS16060	COG0840	transmembrane signaling receptor activity
ECHS_RS16070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECHS_RS16075	COG1609	Transcriptional regulator
ECHS_RS16080	COG3250	beta-galactosidase activity
ECHS_RS16085	COG2731	YhcH YjgK YiaL family protein
ECHS_RS16090	COG0531	amino acid
ECHS_RS16100	COG3408	Glycogen debranching enzyme
ECHS_RS16100	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ECHS_RS16105	COG1902	pentaerythritol trinitrate reductase activity
ECHS_RS16105	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECHS_RS16110	COG5499	transcription regulator containing HTH domain
ECHS_RS16115	COG4680	protein conserved in bacteria
ECHS_RS16130	COG1451	nucleotide metabolic process
ECHS_RS16135	COG2949	membrane
ECHS_RS16140	COG0673	inositol 2-dehydrogenase activity
ECHS_RS16145	COG0861	Integral membrane protein TerC family
ECHS_RS16150	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ECHS_RS16160	COG2721	sulfolactate sulfo-lyase activity
ECHS_RS16170	COG2271	Major facilitator Superfamily
ECHS_RS16195	COG2186	Transcriptional regulator
ECHS_RS16200	COG0586	Pfam SNARE associated Golgi protein
ECHS_RS16210	COG1422	Protein of unknown function (DUF1090)
ECHS_RS16215	COG4575	ribosome binding
ECHS_RS16220	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ECHS_RS16230	COG2259	Doxx family
ECHS_RS16235	COG0435	Glutathione S-transferase
ECHS_RS16240	COG3152	Membrane
ECHS_RS16245	COG3152	Membrane
ECHS_RS16250	COG0583	DNA-binding transcription factor activity
ECHS_RS16255	COG1741	Belongs to the pirin family
ECHS_RS16270	COG0814	amino acid
ECHS_RS16275	COG1760	l-serine dehydratase
ECHS_RS16280	COG0251	oxidation-reduction process
ECHS_RS16285	COG1882	Formate acetyltransferase
ECHS_RS16290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECHS_RS16300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECHS_RS16305	COG0583	DNA-binding transcription factor activity
ECHS_RS16325	COG1929	Belongs to the glycerate kinase type-1 family
ECHS_RS16330	COG2084	Dehydrogenase
ECHS_RS16340	COG2271	Major facilitator Superfamily
ECHS_RS16345	COG2721	sulfolactate sulfo-lyase activity
ECHS_RS16350	COG2002	toxin-antitoxin pair type II binding
ECHS_RS16360	COG1349	DNA-binding transcription factor activity
ECHS_RS16370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS16380	COG3716	PTS system mannose fructose sorbose family IID component
ECHS_RS16385	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS16390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECHS_RS16395	COG2222	sugar isomerase
ECHS_RS16405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS16410	COG3715	PTS system
ECHS_RS16415	COG3716	PTS system mannose fructose sorbose family IID component
ECHS_RS16420	COG0363	glucosamine-6-phosphate deaminase activity
ECHS_RS16425	COG3539	Fimbrial protein
ECHS_RS16430	COG3121	Chaperone
ECHS_RS16435	COG3188	usher protein
ECHS_RS16440	COG3539	Fimbrial protein
ECHS_RS16445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECHS_RS16450	COG3107	peptidoglycan biosynthetic process
ECHS_RS16465	COG2823	Periplasmic or secreted lipoprotein
ECHS_RS16470	COG0701	Predicted permease
ECHS_RS16475	COG0702	epimerase
ECHS_RS16480	COG0693	protein deglycase activity
ECHS_RS16495	COG3153	acetyltransferase
ECHS_RS16500	COG3154	lipid carrier protein
ECHS_RS16505	COG0826	peptidase U32
ECHS_RS16510	COG0826	peptidase U32
ECHS_RS16515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECHS_RS16520	COG0814	amino acid
ECHS_RS16530	COG0513	Belongs to the DEAD box helicase family
ECHS_RS16565	COG0195	Participates in both transcription termination and antitermination
ECHS_RS16585	COG2194	sulfuric ester hydrolase activity
ECHS_RS16595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECHS_RS16605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ECHS_RS16610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ECHS_RS16620	COG1534	Rna-binding protein
ECHS_RS16625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECHS_RS16630	COG2027	D-alanyl-D-alanine carboxypeptidase
ECHS_RS16640	COG0697	spore germination
ECHS_RS16655	COG0142	geranyltranstransferase activity
ECHS_RS16660	COG3423	Transcriptional regulator
ECHS_RS16670	COG5007	Belongs to the BolA IbaG family
ECHS_RS16675	COG3113	response to antibiotic
ECHS_RS16680	COG2854	intermembrane phospholipid transfer
ECHS_RS16685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECHS_RS16690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ECHS_RS16695	COG1127	ABC transporter
ECHS_RS16700	COG0530	calcium, potassium:sodium antiporter activity
ECHS_RS16705	COG0517	IMP dehydrogenase activity
ECHS_RS16705	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECHS_RS16710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ECHS_RS16715	COG3117	lipopolysaccharide transmembrane transporter activity
ECHS_RS16720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ECHS_RS16725	COG1137	ATPase activity
ECHS_RS16730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ECHS_RS16735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECHS_RS16750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS16755	COG0515	serine threonine protein kinase
ECHS_RS16765	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ECHS_RS16770	COG5002	protein histidine kinase activity
ECHS_RS16770	COG0784	Response regulator, receiver
ECHS_RS16770	COG2198	Histidine kinase
ECHS_RS16775	COG1242	4 iron, 4 sulfur cluster binding
ECHS_RS16780	COG0070	glutamate synthase
ECHS_RS16780	COG0067	glutamate synthase
ECHS_RS16780	COG0069	glutamate synthase activity
ECHS_RS16785	COG0493	'glutamate synthase
ECHS_RS16790	COG4804	nuclease activity
ECHS_RS16800	COG2731	YhcH YjgK YiaL family protein
ECHS_RS16835	COG2969	positive regulation of protein catabolic process
ECHS_RS16840	COG0625	glutathione transferase activity
ECHS_RS16855	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ECHS_RS16860	COG3105	Protein conserved in bacteria
ECHS_RS16865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECHS_RS16870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECHS_RS16890	COG2732	(Barnase) inhibitor
ECHS_RS16910	COG0583	DNA-binding transcription factor activity
ECHS_RS16915	COG0312	modulator of DNA gyrase
ECHS_RS16920	COG3164	Protein of unknown function
ECHS_RS16925	COG1530	ribonuclease E activity
ECHS_RS16930	COG0424	maF-like protein
ECHS_RS16935	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ECHS_RS16940	COG1792	Involved in formation and maintenance of cell shape
ECHS_RS16945	COG1077	Cell shape determining protein MreB Mrl
ECHS_RS16955	COG2199	diguanylate cyclase activity
ECHS_RS16955	COG2200	EAL domain
ECHS_RS16960	COG0604	alcohol dehydrogenase
ECHS_RS16975	COG0511	ligase activity, forming carbon-carbon bonds
ECHS_RS16980	COG0439	Biotin carboxylase
ECHS_RS16985	COG3924	membrane
ECHS_RS16990	COG4145	pantothenate transmembrane transporter activity
ECHS_RS17000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECHS_RS17010	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ECHS_RS17020	COG1309	transcriptional regulator
ECHS_RS17025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECHS_RS17030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECHS_RS17045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECHS_RS17050	COG4597	amino acid ABC transporter
ECHS_RS17060	COG1126	abc transporter atp-binding protein
ECHS_RS17100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECHS_RS17120	COG0551	DNA topoisomerase type I activity
ECHS_RS17130	COG0758	DNA mediated transformation
ECHS_RS17150	COG0569	domain protein
ECHS_RS17160	COG3036	rescue of stalled ribosome
ECHS_RS17165	COG0789	Transcriptional regulator
ECHS_RS17205	COG0201	protein transport
ECHS_RS17295	COG0089	rRNA binding
ECHS_RS17320	COG3267	Type II secretory pathway component ExeA
ECHS_RS17320	COG3409	Peptidoglycan-binding domain 1 protein
ECHS_RS17325	COG3031	protein transport across the cell outer membrane
ECHS_RS17330	COG1450	Type ii and iii secretion system protein
ECHS_RS17335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECHS_RS17340	COG1459	type II secretion system
ECHS_RS17345	COG2165	general secretion pathway protein
ECHS_RS17350	COG2165	general secretion pathway protein
ECHS_RS17355	COG2165	general secretion pathway protein
ECHS_RS17360	COG4795	General secretion pathway protein
ECHS_RS17365	COG3156	type II secretion system protein K
ECHS_RS17370	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECHS_RS17375	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECHS_RS17380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ECHS_RS17385	COG2193	ferroxidase activity
ECHS_RS17390	COG2906	2 iron, 2 sulfur cluster binding
ECHS_RS17395	COG3979	chitinase
ECHS_RS17435	COG2964	Protein conserved in bacteria
ECHS_RS17440	COG0545	Peptidyl-prolyl cis-trans isomerase
ECHS_RS17450	COG1047	Peptidyl-prolyl cis-trans
ECHS_RS17455	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ECHS_RS17470	COG0488	(ABC) transporter
ECHS_RS17475	COG0429	hydrolase of the alpha beta-hydrolase fold
ECHS_RS17485	COG3954	Phosphoribulokinase
ECHS_RS17490	COG1765	OsmC-like protein
ECHS_RS17500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECHS_RS17505	COG1289	transmembrane transporter activity
ECHS_RS17510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ECHS_RS17515	COG0512	Glutamine amidotransferase of anthranilate synthase
ECHS_RS17520	COG2184	nucleotidyltransferase activity
ECHS_RS17530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECHS_RS17540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECHS_RS17545	COG2146	nitrite reductase [NAD(P)H] activity
ECHS_RS17550	COG2116	formate transmembrane transporter activity
ECHS_RS17565	COG0531	amino acid
ECHS_RS17570	COG2222	sugar isomerase
ECHS_RS17575	COG1082	Xylose isomerase domain protein TIM barrel
ECHS_RS17580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS17585	COG2188	Transcriptional regulator
ECHS_RS17590	COG0626	cystathionine gamma-synthase activity
ECHS_RS17605	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ECHS_RS17610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ECHS_RS17615	COG3457	Alanine racemase
ECHS_RS17625	COG2188	Transcriptional regulator
ECHS_RS17630	COG0180	Tryptophanyl-tRNA synthetase
ECHS_RS17635	COG0546	phosphoglycolate phosphatase activity
ECHS_RS17640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECHS_RS17645	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ECHS_RS17650	COG3266	domain, Protein
ECHS_RS17665	COG4796	Type ii and iii secretion system protein
ECHS_RS17680	COG3166	PFAM Fimbrial assembly family protein
ECHS_RS17685	COG4972	Pilus assembly protein
ECHS_RS17690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ECHS_RS17695	COG0494	nUDIX hydrolase
ECHS_RS17705	COG1011	Hydrolase
ECHS_RS17710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ECHS_RS17720	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECHS_RS17745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECHS_RS17750	COG2183	response to ionizing radiation
ECHS_RS17755	COG1918	ferrous iron import across plasma membrane
ECHS_RS17760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ECHS_RS17770	COG5464	transposase or invertase
ECHS_RS17790	COG2610	gluconate transmembrane transporter activity
ECHS_RS17795	COG1640	4-alpha-glucanotransferase
ECHS_RS17800	COG0058	SHG alpha-glucan phosphorylase activity
ECHS_RS17815	COG1690	Belongs to the RtcB family
ECHS_RS17820	COG4650	regulator
ECHS_RS17825	COG1349	DNA-binding transcription factor activity
ECHS_RS17840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECHS_RS17860	COG0058	SHG alpha-glucan phosphorylase activity
ECHS_RS17885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECHS_RS17890	COG2095	MarC family integral membrane protein
ECHS_RS17895	COG2610	gluconate transmembrane transporter activity
ECHS_RS17900	COG3265	gluconokinase activity
ECHS_RS17905	COG1609	Transcriptional regulator
ECHS_RS17910	COG1741	Belongs to the pirin family
ECHS_RS17915	COG0673	inositol 2-dehydrogenase activity
ECHS_RS17920	COG1247	-acetyltransferase
ECHS_RS17925	COG3157	Type VI secretion system effector, Hcp
ECHS_RS17940	COG0405	Gamma-glutamyltransferase
ECHS_RS17950	COG0584	glycerophosphoryl diester phosphodiesterase
ECHS_RS17955	COG3842	ATPase activity
ECHS_RS17965	COG1175	transmembrane transport
ECHS_RS17970	COG1653	transport
ECHS_RS17980	COG0410	ABC transporter
ECHS_RS17985	COG0411	ABC transporter
ECHS_RS17990	COG4177	L-phenylalanine transmembrane transporter activity
ECHS_RS17995	COG0559	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS18000	COG0683	leucine binding
ECHS_RS18005	COG0456	acetyltransferase
ECHS_RS18015	COG0683	leucine binding
ECHS_RS18020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECHS_RS18025	COG2177	Part of the ABC transporter FtsEX involved in
ECHS_RS18030	COG2884	Cell division ATP-binding protein ftsE
ECHS_RS18035	COG0552	protein localization to endoplasmic reticulum
ECHS_RS18040	COG0742	ribosomal rna small subunit methyltransferase
ECHS_RS18045	COG3776	membrane
ECHS_RS18055	COG3714	YhhN family
ECHS_RS18070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ECHS_RS18080	COG0477	Major facilitator Superfamily
ECHS_RS18085	COG0628	permease
ECHS_RS18090	COG2091	lysine biosynthetic process via aminoadipic acid
ECHS_RS18095	COG0747	negative chemotaxis
ECHS_RS18100	COG0601	transmembrane transport
ECHS_RS18105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECHS_RS18110	COG0444	Belongs to the ABC transporter superfamily
ECHS_RS18125	COG3209	COG3209 Rhs family protein
ECHS_RS18140	COG5433	transposase activity
ECHS_RS18150	COG0842	Transport permease protein
ECHS_RS18155	COG0842	Transport permease protein
ECHS_RS18155	COG1129	ABC transporter
ECHS_RS18160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECHS_RS18175	COG2081	HI0933 family
ECHS_RS18180	COG0306	phosphate transporter
ECHS_RS18190	COG0589	response to stress
ECHS_RS18195	COG3104	oligopeptide transport
ECHS_RS18205	COG0339	signal peptide processing
ECHS_RS18210	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ECHS_RS18215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECHS_RS18230	COG0640	Transcriptional regulator
ECHS_RS18235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECHS_RS18240	COG1393	Belongs to the ArsC family
ECHS_RS18250	COG3065	identical protein binding
ECHS_RS18255	COG2197	response regulator
ECHS_RS18260	COG1285	pathogenesis
ECHS_RS18275	COG3247	response to pH
ECHS_RS18280	COG2771	luxR family
ECHS_RS18290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECHS_RS18295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECHS_RS18300	COG2207	Transcriptional regulator
ECHS_RS18305	COG2207	Transcriptional regulator
ECHS_RS18310	COG0076	glutamate decarboxylase activity
ECHS_RS18315	COG1858	cytochrome C peroxidase
ECHS_RS18325	COG2197	response regulator
ECHS_RS18330	COG0583	DNA-binding transcription factor activity
ECHS_RS18335	COG1295	ribonuclease BN
ECHS_RS18340	COG0477	Major facilitator Superfamily
ECHS_RS18345	COG2982	Protein involved in outer membrane biogenesis
ECHS_RS18350	COG2200	EAL domain
ECHS_RS18360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS18365	COG0612	Peptidase, M16
ECHS_RS18375	COG2200	EAL domain
ECHS_RS18375	COG2199	diguanylate cyclase activity
ECHS_RS18380	COG3118	belongs to the thioredoxin family
ECHS_RS18380	COG0457	Tetratricopeptide repeat
ECHS_RS18385	COG2194	sulfuric ester hydrolase activity
ECHS_RS18410	COG0814	amino acid
ECHS_RS18415	COG4608	Belongs to the ABC transporter superfamily
ECHS_RS18420	COG0444	Belongs to the ABC transporter superfamily
ECHS_RS18425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECHS_RS18430	COG0601	transmembrane transport
ECHS_RS18440	COG0747	negative chemotaxis
ECHS_RS18455	COG2194	sulfuric ester hydrolase activity
ECHS_RS18460	COG2223	nitrite transmembrane transporter activity
ECHS_RS18465	COG5571	outer membrane autotransporter
ECHS_RS18470	COG2818	Glycosylase
ECHS_RS18475	COG0456	acetyltransferase
ECHS_RS18480	COG0243	molybdopterin cofactor binding
ECHS_RS18485	COG2885	chlorophyll binding
ECHS_RS18500	COG2944	sequence-specific DNA binding
ECHS_RS18505	COG1278	Cold shock
ECHS_RS18515	COG2963	transposase activity
ECHS_RS18520	COG2801	Transposase and inactivated derivatives
ECHS_RS18540	COG3274	enterobacterial common antigen metabolic process
ECHS_RS18545	COG4682	membrane
ECHS_RS18550	COG4682	membrane
ECHS_RS18555	COG1070	Carbohydrate kinase
ECHS_RS18565	COG4213	ABC transporter substrate-binding protein
ECHS_RS18570	COG1129	ABC transporter
ECHS_RS18575	COG4214	carbohydrate transport
ECHS_RS18580	COG1609	Transcriptional regulator
ECHS_RS18580	COG2207	Transcriptional regulator
ECHS_RS18585	COG2992	FlgJ-related protein
ECHS_RS18590	COG0366	Alpha amylase catalytic
ECHS_RS18595	COG3977	Valine--pyruvate aminotransferase
ECHS_RS18605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECHS_RS18610	COG1414	Transcriptional regulator
ECHS_RS18620	COG2731	YhcH YjgK YiaL family protein
ECHS_RS18625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECHS_RS18630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECHS_RS18635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECHS_RS18640	COG1070	Carbohydrate kinase
ECHS_RS18645	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ECHS_RS18650	COG3623	hexulose-6-phosphate isomerase
ECHS_RS18655	COG0235	Class ii aldolase
ECHS_RS18660	COG3713	MltA-interacting MipA family protein
ECHS_RS18665	COG0583	DNA-binding transcription factor activity
ECHS_RS18670	COG1566	PFAM secretion protein HlyD family protein
ECHS_RS18685	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS18690	COG1454	alcohol dehydrogenase
ECHS_RS18695	COG3276	selenocysteine insertion sequence binding
ECHS_RS18705	COG0625	glutathione transferase activity
ECHS_RS18710	COG3209	COG3209 Rhs family protein
ECHS_RS18715	COG3209	COG3209 Rhs family protein
ECHS_RS18720	COG1413	lyase activity
ECHS_RS18725	COG3209	COG3209 Rhs family protein
ECHS_RS18730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECHS_RS18740	COG1566	PFAM secretion protein HlyD family protein
ECHS_RS18750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS18750	COG2213	PTS system mannitol-specific
ECHS_RS18760	COG3722	fumarate hydratase activity
ECHS_RS18780	COG5295	Hep Hag repeat protein
ECHS_RS18785	COG1620	l-lactate permease
ECHS_RS18790	COG2186	Transcriptional regulator
ECHS_RS18800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ECHS_RS18805	COG1045	serine acetyltransferase
ECHS_RS18820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECHS_RS18825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECHS_RS18835	COG4942	peptidase
ECHS_RS18840	COG2861	carbohydrate metabolic process
ECHS_RS18845	COG1216	Glycosyl transferase, family 2
ECHS_RS18855	COG0156	8-amino-7-oxononanoate synthase activity
ECHS_RS18865	COG0859	PFAM glycosyl transferase family 9
ECHS_RS18870	COG0859	PFAM glycosyl transferase family 9
ECHS_RS18875	COG3307	-O-antigen
ECHS_RS18880	COG1216	Glycosyl transferase, family 2
ECHS_RS18885	COG1442	glycosyl transferase family 8
ECHS_RS18890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ECHS_RS18905	COG0515	serine threonine protein kinase
ECHS_RS18910	COG0438	transferase activity, transferring glycosyl groups
ECHS_RS18915	COG0859	PFAM glycosyl transferase family 9
ECHS_RS18920	COG1519	Transferase
ECHS_RS18950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECHS_RS18975	COG1561	YicC-like family, N-terminal region
ECHS_RS18985	COG2860	membrane
ECHS_RS18995	COG0194	GDP metabolic process
ECHS_RS19005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECHS_RS19010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECHS_RS19015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECHS_RS19020	COG0786	glutamate:sodium symporter activity
ECHS_RS19025	COG2233	PERMEase
ECHS_RS19030	COG2982	Protein involved in outer membrane biogenesis
ECHS_RS19035	COG1501	Belongs to the glycosyl hydrolase 31 family
ECHS_RS19040	COG2211	Major facilitator Superfamily
ECHS_RS19055	COG2814	Major facilitator Superfamily
ECHS_RS19060	COG0697	spore germination
ECHS_RS19065	COG1464	Belongs to the NlpA lipoprotein family
ECHS_RS19090	COG2252	PERMEase
ECHS_RS19100	COG2271	Major facilitator Superfamily
ECHS_RS19105	COG2271	Major facilitator Superfamily
ECHS_RS19110	COG3851	Histidine kinase
ECHS_RS19115	COG2197	response regulator
ECHS_RS19120	COG0440	acetolactate synthase activity
ECHS_RS19125	COG0028	Belongs to the TPP enzyme family
ECHS_RS19150	COG2814	Major facilitator Superfamily
ECHS_RS19155	COG0641	radical SAM
ECHS_RS19165	COG2149	membrane
ECHS_RS19170	COG0675	Transposase, IS605 OrfB family
ECHS_RS19190	COG2188	Transcriptional regulator
ECHS_RS19215	COG5645	(Lipo)protein
ECHS_RS19220	COG0823	Involved in the tonB-independent uptake of proteins
ECHS_RS19230	COG2271	Major facilitator Superfamily
ECHS_RS19240	COG0800	Aldolase
ECHS_RS19245	COG3734	2-keto-3-deoxy-galactonokinase
ECHS_RS19250	COG2186	Transcriptional regulator
ECHS_RS19260	COG0561	phosphatase activity
ECHS_RS19265	COG3753	Protein conserved in bacteria
ECHS_RS19275	COG0187	DNA topoisomerase II activity
ECHS_RS19285	COG0592	DNA-directed DNA polymerase activity
ECHS_RS19330	COG0814	amino acid
ECHS_RS19345	COG2091	lysine biosynthetic process via aminoadipic acid
ECHS_RS19350	COG0431	NADPH-dependent FMN reductase
ECHS_RS19355	COG2252	PERMEase
ECHS_RS19360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECHS_RS19370	COG3196	Protein conserved in bacteria
ECHS_RS19375	COG0363	glucosamine-6-phosphate deaminase activity
ECHS_RS19380	COG2382	esterase
ECHS_RS19390	COG2723	6-phospho-beta-galactosidase activity
ECHS_RS19395	COG1263	PTS System
ECHS_RS19395	COG2190	(PTS) system
ECHS_RS19395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS19400	COG3711	transcriptional antiterminator
ECHS_RS19405	COG0704	Plays a role in the regulation of phosphate uptake
ECHS_RS19410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ECHS_RS19415	COG0581	inorganic phosphate transmembrane transporter activity
ECHS_RS19420	COG0573	inorganic phosphate transmembrane transporter activity
ECHS_RS19425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECHS_RS19430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ECHS_RS19480	COG3312	ion transport
ECHS_RS19495	COG0716	FMN binding
ECHS_RS19500	COG1522	sequence-specific DNA binding
ECHS_RS19530	COG1129	ABC transporter
ECHS_RS19535	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS19540	COG1879	ABC-type sugar transport system periplasmic component
ECHS_RS19545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS19550	COG1609	Transcriptional regulator
ECHS_RS19555	COG2801	Transposase and inactivated derivatives
ECHS_RS19560	COG2963	transposase activity
ECHS_RS19565	COG1609	Transcriptional regulator
ECHS_RS19570	COG0477	Major facilitator Superfamily
ECHS_RS19575	COG2186	Transcriptional regulator
ECHS_RS19615	COG3085	chromosome segregation
ECHS_RS19620	COG0606	chelatase, subunit chli
ECHS_RS19635	COG3978	acetolactate synthase activity
ECHS_RS19640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECHS_RS19650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECHS_RS19655	COG0583	DNA-binding transcription factor activity
ECHS_RS19665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECHS_RS19675	COG0210	DNA helicase
ECHS_RS19690	COG3118	belongs to the thioredoxin family
ECHS_RS19700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECHS_RS19710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECHS_RS19715	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECHS_RS19720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ECHS_RS19725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ECHS_RS19730	COG1088	dTDP-glucose 4,6-dehydratase activity
ECHS_RS19735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ECHS_RS19740	COG0456	acetyltransferase
ECHS_RS19745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ECHS_RS19750	COG2244	polysaccharide biosynthetic process
ECHS_RS19770	COG1113	amino acid transport
ECHS_RS19795	COG0641	radical SAM
ECHS_RS19800	COG3119	arylsulfatase activity
ECHS_RS19805	COG3071	HemY protein
ECHS_RS19810	COG2959	enzyme of heme biosynthesis
ECHS_RS19815	COG1587	Uroporphyrinogen-III synthase
ECHS_RS19825	COG3072	Adenylate cyclase
ECHS_RS19850	COG5567	small periplasmic lipoprotein
ECHS_RS19860	COG3159	Protein conserved in bacteria
ECHS_RS19870	COG1011	Hydrolase
ECHS_RS19875	COG0210	DNA helicase
ECHS_RS19880	COG3698	Phosphodiester glycosidase
ECHS_RS19890	COG0598	Magnesium transport protein CorA
ECHS_RS19905	COG2962	Rard protein
ECHS_RS19910	COG2050	protein possibly involved in aromatic compounds catabolism
ECHS_RS19915	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ECHS_RS19920	COG0514	ATP-dependent DNA helicase (RecQ)
ECHS_RS19925	COG1280	lysine exporter protein (LysE YggA)
ECHS_RS19930	COG1280	lysine exporter protein (LysE YggA)
ECHS_RS19935	COG2267	carboxylic ester hydrolase activity
ECHS_RS19940	COG0561	phosphatase activity
ECHS_RS19945	COG0697	spore germination
ECHS_RS19950	COG0583	DNA-binding transcription factor activity
ECHS_RS19960	COG0412	Dienelactone hydrolase
ECHS_RS19965	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ECHS_RS19970	COG1322	Protein conserved in bacteria
ECHS_RS19980	COG3165	ubiquinone biosynthetic process from chorismate
ECHS_RS19990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECHS_RS19995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECHS_RS20000	COG0805	protein transport
ECHS_RS20005	COG0084	hydrolase, TatD family'
ECHS_RS20010	COG0250	Participates in transcription elongation, termination and antitermination
ECHS_RS20020	COG0543	2 iron, 2 sulfur cluster binding
ECHS_RS20040	COG1739	Uncharacterized protein family UPF0029
ECHS_RS20045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECHS_RS20050	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ECHS_RS20080	COG1763	Mo-molybdopterin cofactor biosynthetic process
ECHS_RS20085	COG0746	molybdenum cofactor guanylyltransferase activity
ECHS_RS20090	COG3084	Protein conserved in bacteria
ECHS_RS20095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ECHS_RS20100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECHS_RS20105	COG5339	Protein conserved in bacteria
ECHS_RS20110	COG0204	Acyl-transferase
ECHS_RS20120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECHS_RS20120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECHS_RS20130	COG3078	GTPase activator activity
ECHS_RS20135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECHS_RS20145	COG2204	response regulator
ECHS_RS20150	COG3852	Histidine kinase
ECHS_RS20155	COG0174	glutamine synthetase
ECHS_RS20165	COG1217	gtp-binding protein TYPA
ECHS_RS20170	COG2188	Transcriptional regulator
ECHS_RS20175	COG1082	Xylose isomerase domain protein TIM barrel
ECHS_RS20180	COG2271	Major facilitator Superfamily
ECHS_RS20185	COG1349	DNA-binding transcription factor activity
ECHS_RS20190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECHS_RS20195	COG2084	Dehydrogenase
ECHS_RS20200	COG3684	Belongs to the aldolase LacD family
ECHS_RS20205	COG1063	alcohol dehydrogenase
ECHS_RS20215	COG0477	Major facilitator Superfamily
ECHS_RS20225	COG1011	Hydrolase
ECHS_RS20240	COG0456	acetyltransferase
ECHS_RS20245	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECHS_RS20250	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECHS_RS20260	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS20270	COG2864	formate dehydrogenase
ECHS_RS20275	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS20280	COG0243	molybdopterin cofactor binding
ECHS_RS20280	COG3383	formate dehydrogenase (NAD+) activity
ECHS_RS20285	COG0243	molybdopterin cofactor binding
ECHS_RS20285	COG3383	formate dehydrogenase (NAD+) activity
ECHS_RS20300	COG3711	transcriptional antiterminator
ECHS_RS20300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS20305	COG1363	Peptidase, m42
ECHS_RS20310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS20310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS20315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS20360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECHS_RS20375	COG2258	MOSC domain
ECHS_RS20380	COG2205	protein histidine kinase activity
ECHS_RS20385	COG0745	RESPONSE REGULATOR receiver
ECHS_RS20390	COG3678	ATP-independent chaperone mediated protein folding
ECHS_RS20405	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ECHS_RS20425	COG3152	Membrane
ECHS_RS20430	COG3691	Protein conserved in bacteria
ECHS_RS20435	COG0589	response to stress
ECHS_RS20440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECHS_RS20445	COG1494	fructose-1,6-bisphosphatase
ECHS_RS20455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ECHS_RS20470	COG1575	Belongs to the MenA family. Type 1 subfamily
ECHS_RS20485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECHS_RS20490	COG1609	Transcriptional regulator
ECHS_RS20495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ECHS_RS20510	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ECHS_RS20520	COG0626	cystathionine gamma-synthase activity
ECHS_RS20525	COG0527	aspartate kinase activity
ECHS_RS20525	COG0460	homoserine dehydrogenase
ECHS_RS20535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ECHS_RS20545	COG0697	spore germination
ECHS_RS20550	COG3738	Protein conserved in bacteria
ECHS_RS20555	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS20560	COG0371	Dehydrogenase
ECHS_RS20565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECHS_RS20570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECHS_RS20570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS20570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECHS_RS20575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS20580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS20585	COG1882	Formate acetyltransferase
ECHS_RS20590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECHS_RS20595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECHS_RS20600	COG2207	Transcriptional regulator
ECHS_RS20605	COG2194	sulfuric ester hydrolase activity
ECHS_RS20620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ECHS_RS20635	COG0583	DNA-binding transcription factor activity
ECHS_RS20695	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ECHS_RS20695	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ECHS_RS20735	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECHS_RS20740	COG0250	Participates in transcription elongation, termination and antitermination
ECHS_RS20780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ECHS_RS20790	COG2104	thiamine diphosphate biosynthetic process
ECHS_RS20795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECHS_RS20830	COG3068	Protein conserved in bacteria
ECHS_RS20845	COG3678	ATP-independent chaperone mediated protein folding
ECHS_RS20850	COG4191	Histidine kinase
ECHS_RS20855	COG2204	response regulator
ECHS_RS20860	COG0151	Belongs to the GarS family
ECHS_RS20900	COG0456	acetyltransferase
ECHS_RS20910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECHS_RS20915	COG2224	Isocitrate lyase
ECHS_RS20935	COG1414	Transcriptional regulator
ECHS_RS20940	COG0646	methionine synthase
ECHS_RS20940	COG1410	methionine synthase
ECHS_RS20945	COG1283	sodium-dependent phosphate transmembrane transporter activity
ECHS_RS20955	COG1187	pseudouridine synthase activity
ECHS_RS20970	COG3541	Predicted nucleotidyltransferase
ECHS_RS20975	COG0542	response to heat
ECHS_RS20980	COG0527	aspartate kinase activity
ECHS_RS21005	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECHS_RS21025	COG2814	Major facilitator Superfamily
ECHS_RS21025	COG0477	Major facilitator Superfamily
ECHS_RS21030	COG3833	ABC-type maltose transport systems, permease component
ECHS_RS21035	COG1175	transmembrane transport
ECHS_RS21040	COG2182	Extracellular solute-binding protein
ECHS_RS21050	COG3842	ATPase activity
ECHS_RS21070	COG1357	PFAM Pentapeptide repeats (8 copies)
ECHS_RS21090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ECHS_RS21100	COG0534	Mate efflux family protein
ECHS_RS21105	COG3237	CsbD-like
ECHS_RS21110	COG0735	belongs to the Fur family
ECHS_RS21125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECHS_RS21135	COG0604	alcohol dehydrogenase
ECHS_RS21140	COG0305	Participates in initiation and elongation during chromosome replication
ECHS_RS21145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECHS_RS21150	COG1448	Aminotransferase
ECHS_RS21165	COG0432	Pfam Uncharacterised protein family UPF0047
ECHS_RS21170	COG2315	Protein conserved in bacteria
ECHS_RS21175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ECHS_RS21180	COG0629	single-stranded DNA binding
ECHS_RS21190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECHS_RS21195	COG2207	Transcriptional regulator
ECHS_RS21200	COG0789	Transcriptional regulator
ECHS_RS21205	COG2252	PERMEase
ECHS_RS21210	COG0025	NhaP-type Na H and K H
ECHS_RS21225	COG3162	membrane
ECHS_RS21230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECHS_RS21240	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ECHS_RS21245	COG0437	4 iron, 4 sulfur cluster binding
ECHS_RS21250	COG3301	Polysulphide reductase, NrfD
ECHS_RS21255	COG1138	Cytochrome C-type biogenesis protein
ECHS_RS21260	COG3088	subunit of a heme lyase
ECHS_RS21265	COG4235	cytochrome complex assembly
ECHS_RS21270	COG1301	dicarboxylic acid transport
ECHS_RS21275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECHS_RS21280	COG3383	formate dehydrogenase (NAD+) activity
ECHS_RS21285	COG3383	formate dehydrogenase (NAD+) activity
ECHS_RS21295	COG1289	transmembrane transporter activity
ECHS_RS21300	COG1566	PFAM secretion protein HlyD family protein
ECHS_RS21310	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ECHS_RS21315	COG0698	ribose 5-phosphate isomerase
ECHS_RS21325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ECHS_RS21330	COG0456	acetyltransferase
ECHS_RS21335	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ECHS_RS21340	COG3454	Phosphonate metabolism
ECHS_RS21345	COG4778	phosphonate C-P lyase system protein PhnL
ECHS_RS21350	COG4107	phosphonate C-P lyase system protein PhnK
ECHS_RS21355	COG3627	carbon phosphorus lyase activity
ECHS_RS21360	COG3626	phosphonate metabolism
ECHS_RS21365	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ECHS_RS21370	COG3624	Phosphonate C-P lyase system protein PhnG
ECHS_RS21375	COG2188	Transcriptional regulator
ECHS_RS21380	COG3639	organic phosphonate transmembrane transporter activity
ECHS_RS21385	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ECHS_RS21395	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ECHS_RS21400	COG2824	Alkylphosphonate utilization operon protein PhnA
ECHS_RS21415	COG0477	Major facilitator Superfamily
ECHS_RS21425	COG0642	Histidine kinase
ECHS_RS21430	COG0745	RESPONSE REGULATOR receiver
ECHS_RS21435	COG2194	sulfuric ester hydrolase activity
ECHS_RS21440	COG0531	amino acid
ECHS_RS21445	COG2207	Transcriptional regulator
ECHS_RS21450	COG1982	Orn Lys Arg decarboxylase major
ECHS_RS21455	COG2169	Transcriptional regulator
ECHS_RS21465	COG1486	melibiose metabolic process
ECHS_RS21470	COG2211	Major facilitator Superfamily
ECHS_RS21475	COG3647	Membrane
ECHS_RS21480	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECHS_RS21480	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECHS_RS21485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECHS_RS21495	COG4565	transcriptional regulatory protein
ECHS_RS21500	COG3290	protein histidine kinase activity
ECHS_RS21505	COG3592	Divergent 4Fe-4S mono-cluster
ECHS_RS21510	COG2388	GCN5-related N-acetyl-transferase
ECHS_RS21525	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECHS_RS21530	COG3104	oligopeptide transport
ECHS_RS21535	COG1982	Orn Lys Arg decarboxylase major
ECHS_RS21540	COG0531	amino acid
ECHS_RS21545	COG3710	Transcriptional regulator
ECHS_RS21555	COG1309	transcriptional regulator
ECHS_RS21570	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECHS_RS21575	COG1027	Aspartate ammonia-lyase
ECHS_RS21580	COG3030	protein affecting phage T7 exclusion by the F plasmid
ECHS_RS21585	COG0531	amino acid
ECHS_RS21605	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS21615	COG1509	lysine 2,3-aminomutase activity
ECHS_RS21625	COG5510	response to toxic substance
ECHS_RS21630	COG5510	response to toxic substance
ECHS_RS21635	COG2076	Multidrug Resistance protein
ECHS_RS21640	COG3040	lipid binding
ECHS_RS21645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECHS_RS21660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECHS_RS21665	COG1053	succinate dehydrogenase
ECHS_RS21675	COG0531	amino acid
ECHS_RS21680	COG1511	domain protein
ECHS_RS21680	COG3264	Mechanosensitive ion channel
ECHS_RS21715	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ECHS_RS21720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ECHS_RS21720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECHS_RS21725	COG0802	atpase or kinase
ECHS_RS21730	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECHS_RS21750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ECHS_RS21755	COG0330	HflC and HflK could
ECHS_RS21760	COG0330	HflC and HflK could
ECHS_RS21765	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ECHS_RS21780	COG0557	exoribonuclease II activity
ECHS_RS21785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECHS_RS21790	COG3789	protein conserved in bacteria
ECHS_RS21795	COG1842	Phage shock protein A
ECHS_RS21805	COG3766	membrane
ECHS_RS21810	COG5463	Belongs to the UPF0441 family
ECHS_RS21815	COG0754	glutathionylspermidine amidase activity
ECHS_RS21820	COG1960	acyl-CoA dehydrogenase activity
ECHS_RS21830	COG3650	response to hydrogen peroxide
ECHS_RS21835	COG1073	alpha beta
ECHS_RS21850	COG3037	sugar-specific permease SgaT UlaA
ECHS_RS21895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ECHS_RS21905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECHS_RS21915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECHS_RS21920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECHS_RS21925	COG4670	ketone body catabolic process
ECHS_RS21930	COG1024	Enoyl-CoA hydratase
ECHS_RS21945	COG1309	transcriptional regulator
ECHS_RS21950	COG3061	Opacity-associated protein A
ECHS_RS21955	COG0545	Peptidyl-prolyl cis-trans isomerase
ECHS_RS21960	COG1113	amino acid transport
ECHS_RS21980	COG0697	spore germination
ECHS_RS21985	COG0702	epimerase
ECHS_RS21990	COG1733	regulation of RNA biosynthetic process
ECHS_RS21995	COG0737	Belongs to the 5'-nucleotidase family
ECHS_RS22000	COG1218	3'(2'),5'-bisphosphate nucleotidase
ECHS_RS22005	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECHS_RS22015	COG1253	flavin adenine dinucleotide binding
ECHS_RS22020	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS22035	COG0729	surface antigen
ECHS_RS22040	COG2911	Protein conserved in bacteria
ECHS_RS22045	COG2105	PFAM AIG2 family protein
ECHS_RS22050	COG2336	PFAM SpoVT AbrB
ECHS_RS22055	COG2337	Toxic component of a toxin-antitoxin (TA) module
ECHS_RS22060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ECHS_RS22065	COG1879	ABC-type sugar transport system periplasmic component
ECHS_RS22070	COG1129	ABC transporter
ECHS_RS22075	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS22080	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECHS_RS22090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECHS_RS22100	COG0312	modulator of DNA gyrase
ECHS_RS22105	COG3783	Cytochrome b(562)
ECHS_RS22110	COG0602	queuosine metabolic process
ECHS_RS22115	COG1328	CTP reductase activity
ECHS_RS22120	COG0366	Alpha amylase catalytic
ECHS_RS22125	COG1263	PTS System
ECHS_RS22125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECHS_RS22130	COG1609	Transcriptional regulator
ECHS_RS22135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ECHS_RS22140	COG3547	Transposase (IS116 IS110 IS902 family)
ECHS_RS22145	COG0251	oxidation-reduction process
ECHS_RS22170	COG0251	oxidation-reduction process
ECHS_RS22175	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS22180	COG1309	transcriptional regulator
ECHS_RS22185	COG2731	YhcH YjgK YiaL family protein
ECHS_RS22205	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ECHS_RS22210	COG0456	acetyltransferase
ECHS_RS22215	COG4269	membrane
ECHS_RS22220	COG0525	valine-tRNA ligase activity
ECHS_RS22225	COG2927	DNA polymerase III (CHI subunit)
ECHS_RS22235	COG0795	lipopolysaccharide-transporting ATPase activity
ECHS_RS22240	COG0795	lipopolysaccharide-transporting ATPase activity
ECHS_RS22245	COG0433	COG0433 Predicted ATPase
ECHS_RS22250	COG1609	Transcriptional regulator
ECHS_RS22255	COG2610	gluconate transmembrane transporter activity
ECHS_RS22260	COG1028	Short-chain dehydrogenase reductase Sdr
ECHS_RS22265	COG1063	alcohol dehydrogenase
ECHS_RS22270	COG3265	gluconokinase activity
ECHS_RS22275	COG1064	alcohol dehydrogenase
ECHS_RS22295	COG2801	Transposase and inactivated derivatives
ECHS_RS22300	COG2963	transposase activity
ECHS_RS22310	COG1401	restriction endodeoxyribonuclease activity
ECHS_RS22330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECHS_RS22345	COG0582	viral genome integration into host DNA
ECHS_RS22350	COG4974	Belongs to the 'phage' integrase family
ECHS_RS22365	COG3539	Fimbrial protein
ECHS_RS22370	COG3121	Chaperone
ECHS_RS22375	COG3188	usher protein
ECHS_RS22380	COG3539	Fimbrial protein
ECHS_RS22385	COG3539	Fimbrial protein
ECHS_RS22390	COG3539	Fimbrial protein
ECHS_RS22395	COG2610	gluconate transmembrane transporter activity
ECHS_RS22410	COG0246	Mannitol dehydrogenase
ECHS_RS22420	COG2186	Transcriptional regulator
ECHS_RS22445	COG0583	DNA-binding transcription factor activity
ECHS_RS22450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECHS_RS22455	COG0700	Nucleoside recognition
ECHS_RS22460	COG3366	ferrous iron transmembrane transporter activity
ECHS_RS22470	COG0477	Major facilitator Superfamily
ECHS_RS22485	COG1924	4 iron, 4 sulfur cluster binding
ECHS_RS22490	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ECHS_RS22495	COG2733	membrane
ECHS_RS22500	COG2814	Major facilitator Superfamily
ECHS_RS22510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECHS_RS22515	COG5457	Domain of unknown function (DUF1127)
ECHS_RS22530	COG0523	cobalamin synthesis protein
ECHS_RS22535	COG2879	small protein
ECHS_RS22540	COG1966	Carbon starvation protein
ECHS_RS22550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECHS_RS22555	COG2368	4-hydroxyphenylacetate
ECHS_RS22575	COG3971	2-oxopent-4-enoate hydratase activity
ECHS_RS22585	COG3384	dioxygenase
ECHS_RS22590	COG1012	belongs to the aldehyde dehydrogenase family
ECHS_RS22595	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECHS_RS22600	COG1846	Transcriptional regulator
ECHS_RS22605	COG0840	transmembrane signaling receptor activity
ECHS_RS22610	COG2271	Major facilitator Superfamily
ECHS_RS22615	COG1802	Transcriptional regulator
ECHS_RS22620	COG1063	alcohol dehydrogenase
ECHS_RS22635	COG1484	DNA-dependent DNA replication
ECHS_RS22650	COG2966	Psort location CytoplasmicMembrane, score
ECHS_RS22655	COG2197	response regulator
ECHS_RS22660	COG2197	response regulator
ECHS_RS22665	COG4114	ferric iron reductase
ECHS_RS22695	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ECHS_RS22700	COG0456	acetyltransferase
ECHS_RS22705	COG1011	Hydrolase
ECHS_RS22715	COG2823	Periplasmic or secreted lipoprotein
ECHS_RS22725	COG4667	esterase of the alpha-beta hydrolase superfamily
ECHS_RS22730	COG0084	hydrolase, TatD family'
ECHS_RS22735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECHS_RS22740	COG1328	CTP reductase activity
ECHS_RS22780	COG3726	membrane protein affecting hemolysin expression
ECHS_RS22785	COG0560	Phosphoserine phosphatase
ECHS_RS22790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECHS_RS22795	COG1056	cytidyltransferase-related domain
ECHS_RS22795	COG3172	ATPase kinase involved in NAD metabolism
ECHS_RS22805	COG0488	(ABC) transporter
ECHS_RS22810	COG0741	lytic transglycosylase activity
ECHS_RS22830	COG2207	Transcriptional regulator
ECHS_RS22830	COG3708	Transcriptional regulator
ECHS_RS22835	COG3045	CreA protein
ECHS_RS22840	COG0745	RESPONSE REGULATOR receiver
ECHS_RS22845	COG2205	protein histidine kinase activity
ECHS_RS22850	COG4452	Inner membrane protein CreD
ECHS_RS22855	COG0745	RESPONSE REGULATOR receiver
ECHS_RS22865	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA