locus-tag	class	description
HS093_RS00025	COG4695	Portal protein
HS093_RS00110	COG5301	cellulose 1,4-beta-cellobiosidase activity
HS093_RS00110	COG5301	cellulose 1,4-beta-cellobiosidase activity
HS093_RS00165	COG0826	peptidase U32
HS093_RS00175	COG3609	addiction module antidote protein, CC2985 family
HS093_RS00185	COG0745	RESPONSE REGULATOR receiver
HS093_RS00190	COG2205	protein histidine kinase activity
HS093_RS00230	COG4245	von Willebrand factor, type A
HS093_RS00235	COG0631	protein serine/threonine phosphatase activity
HS093_RS00240	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HS093_RS00245	COG0443	Heat shock 70 kDa protein
HS093_RS00250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HS093_RS00255	COG3447	MASE1 domain protein
HS093_RS00255	COG5001	Diguanylate cyclase
HS093_RS00255	COG5002	protein histidine kinase activity
HS093_RS00260	COG0572	uridine kinase
HS093_RS00270	COG2982	Protein involved in outer membrane biogenesis
HS093_RS00275	COG1253	flavin adenine dinucleotide binding
HS093_RS00285	COG1596	polysaccharide export
HS093_RS00290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HS093_RS00295	COG0489	protein tyrosine kinase activity
HS093_RS00295	COG3206	protein involved in exopolysaccharide biosynthesis
HS093_RS00300	COG0463	Glycosyl transferase, family 2
HS093_RS00305	COG1045	serine acetyltransferase
HS093_RS00310	COG0438	transferase activity, transferring glycosyl groups
HS093_RS00320	COG1216	Glycosyl transferase, family 2
HS093_RS00325	COG0110	maltose O-acetyltransferase activity
HS093_RS00330	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HS093_RS00335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HS093_RS00340	COG1051	belongs to the nudix hydrolase family
HS093_RS00345	COG0297	glycogen (starch) synthase activity
HS093_RS00350	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HS093_RS00350	COG0662	Cupin 2, conserved barrel domain protein
HS093_RS00355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HS093_RS00360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HS093_RS00365	COG2244	polysaccharide biosynthetic process
HS093_RS00370	COG2327	Polysaccharide pyruvyl transferase
HS093_RS00375	COG0438	transferase activity, transferring glycosyl groups
HS093_RS00385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HS093_RS00415	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HS093_RS00425	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HS093_RS00445	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HS093_RS00450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HS093_RS00450	COG0131	Imidazoleglycerol-phosphate dehydratase
HS093_RS00460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HS093_RS00475	COG2161	toxin-antitoxin pair type II binding
HS093_RS00480	COG4115	mRNA cleavage
HS093_RS00485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HS093_RS00490	COG0583	DNA-binding transcription factor activity
HS093_RS00500	COG0531	amino acid
HS093_RS00505	COG2391	methyltransferase activity
HS093_RS00510	COG0425	Belongs to the sulfur carrier protein TusA family
HS093_RS00515	COG2925	Exonuclease
HS093_RS00520	COG1686	Belongs to the peptidase S11 family
HS093_RS00530	COG1289	transmembrane transporter activity
HS093_RS00555	COG4656	Part of a membrane complex involved in electron transport
HS093_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS00560	COG1454	alcohol dehydrogenase
HS093_RS00575	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HS093_RS00590	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HS093_RS00650	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HS093_RS00665	COG1376	ErfK ybiS ycfS ynhG family protein
HS093_RS00675	COG0583	DNA-binding transcription factor activity
HS093_RS00680	COG0583	DNA-binding transcription factor activity
HS093_RS00690	COG0534	Mate efflux family protein
HS093_RS00700	COG0217	transcriptional regulatory protein
HS093_RS00705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HS093_RS00710	COG0477	Major facilitator Superfamily
HS093_RS00740	COG3038	cytochrome b561
HS093_RS00745	COG3443	Belongs to the bacterial solute-binding protein 9 family
HS093_RS00760	COG2351	hydroxyisourate hydrolase activity
HS093_RS00765	COG0745	RESPONSE REGULATOR receiver
HS093_RS00770	COG2205	protein histidine kinase activity
HS093_RS00785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS093_RS00795	COG1418	mRNA catabolic process
HS093_RS00800	COG0270	DNA (cytosine-5-)-methyltransferase activity
HS093_RS00805	COG3727	T/G mismatch-specific endonuclease activity
HS093_RS00810	COG0697	spore germination
HS093_RS00815	COG2354	Protein conserved in bacteria
HS093_RS00820	COG5475	Uncharacterized small protein (DUF2158)
HS093_RS00845	COG2197	response regulator
HS093_RS00850	COG1684	flagellar biosynthetic protein fliR
HS093_RS00855	COG1987	bacterial-type flagellum assembly
HS093_RS00860	COG1338	Plays a role in the flagellum-specific transport system
HS093_RS00865	COG3190	flagellar
HS093_RS00870	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HS093_RS00875	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HS093_RS00880	COG1580	Controls the rotational direction of flagella during chemotaxis
HS093_RS00885	COG3144	bacterial-type flagellum assembly
HS093_RS00890	COG2882	bacterial-type flagellum organization
HS093_RS00895	COG1157	protein secretion by the type III secretion system
HS093_RS00900	COG1317	bacterial-type flagellum organization
HS093_RS00905	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HS093_RS00910	COG1766	The M ring may be actively involved in energy transduction
HS093_RS00920	COG2135	peptidase activity
HS093_RS00925	COG0425	Belongs to the sulfur carrier protein TusA family
HS093_RS00930	COG2391	methyltransferase activity
HS093_RS00940	COG0366	Alpha amylase catalytic
HS093_RS00950	COG1516	flagellar protein fliS
HS093_RS00965	COG1191	sigma factor activity
HS093_RS00975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS00985	COG0765	amino acid transport
HS093_RS00990	COG1126	abc transporter atp-binding protein
HS093_RS00995	COG2197	response regulator
HS093_RS01010	COG2197	response regulator
HS093_RS01040	COG3318	Belongs to the UPF0149 family
HS093_RS01040	COG3012	SEC-C Motif Domain Protein
HS093_RS01045	COG0814	amino acid
HS093_RS01055	COG1528	Iron-storage protein
HS093_RS01075	COG1528	Iron-storage protein
HS093_RS01080	COG1879	ABC-type sugar transport system periplasmic component
HS093_RS01085	COG1129	ABC transporter
HS093_RS01090	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS093_RS01095	COG1877	trehalose-phosphatase activity
HS093_RS01105	COG0589	response to stress
HS093_RS01120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HS093_RS01125	COG1360	Flagellar Motor Protein
HS093_RS01130	COG2198	Histidine kinase
HS093_RS01130	COG0643	Histidine kinase
HS093_RS01135	COG0835	chemotaxis
HS093_RS01140	COG0840	transmembrane signaling receptor activity
HS093_RS01145	COG0840	transmembrane signaling receptor activity
HS093_RS01150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HS093_RS01155	COG2201	protein-glutamate methylesterase activity
HS093_RS01160	COG0745	RESPONSE REGULATOR receiver
HS093_RS01165	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HS093_RS01170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HS093_RS01175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HS093_RS01185	COG3755	Protein conserved in bacteria
HS093_RS01195	COG3102	Protein conserved in bacteria
HS093_RS01220	COG0243	molybdopterin cofactor binding
HS093_RS01235	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HS093_RS01240	COG1801	Protein of unknown function DUF72
HS093_RS01245	COG1335	isochorismatase
HS093_RS01255	COG0494	nUDIX hydrolase
HS093_RS01260	COG0217	transcriptional regulatory protein
HS093_RS01290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HS093_RS01300	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HS093_RS01305	COG0739	heme binding
HS093_RS01310	COG1560	Kdo2-lipid A biosynthetic process
HS093_RS01330	COG3842	ATPase activity
HS093_RS01340	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HS093_RS01350	COG2182	Extracellular solute-binding protein
HS093_RS01355	COG1175	transmembrane transport
HS093_RS01360	COG3833	ABC-type maltose transport systems, permease component
HS093_RS01385	COG0469	pyruvate kinase activity
HS093_RS01390	COG1737	Transcriptional regulator
HS093_RS01395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HS093_RS01400	COG0129	dihydroxy-acid dehydratase activity
HS093_RS01405	COG0800	Aldolase
HS093_RS01415	COG3141	response to X-ray
HS093_RS01425	COG2979	Protein of unknown function (DUF533)
HS093_RS01430	COG1770	oligopeptidase
HS093_RS01435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HS093_RS01440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HS093_RS01450	COG2372	response to copper ion
HS093_RS01455	COG1276	copper resistance
HS093_RS01465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HS093_RS01485	COG3008	intermembrane lipid transfer
HS093_RS01490	COG2995	paraquat-inducible protein a
HS093_RS01495	COG1956	GAF domain-containing protein
HS093_RS01505	COG0793	Belongs to the peptidase S41A family
HS093_RS01515	COG2814	Major facilitator Superfamily
HS093_RS01520	COG1414	Transcriptional regulator
HS093_RS01550	COG2226	methyltransferase
HS093_RS01565	COG3716	PTS system mannose fructose sorbose family IID component
HS093_RS01570	COG3715	PTS system
HS093_RS01575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS01575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS01580	COG1253	flavin adenine dinucleotide binding
HS093_RS01585	COG2200	EAL domain
HS093_RS01590	COG1760	l-serine dehydratase
HS093_RS01600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HS093_RS01615	COG0251	oxidation-reduction process
HS093_RS01620	COG1199	ATP-dependent helicase activity
HS093_RS01625	COG1214	PFAM Peptidase M22, glycoprotease
HS093_RS01630	COG3065	identical protein binding
HS093_RS01635	COG0318	PFAM AMP-dependent synthetase and ligase
HS093_RS01640	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HS093_RS01645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS093_RS01650	COG4638	Rieske (2fe-2S)
HS093_RS01655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HS093_RS01660	COG0473	3-isopropylmalate dehydrogenase activity
HS093_RS01665	COG0583	DNA-binding transcription factor activity
HS093_RS01675	COG3615	Tellurite resistance protein tehB
HS093_RS01690	COG0675	Transposase, IS605 OrfB family
HS093_RS01695	COG2261	transglycosylase associated protein
HS093_RS01710	COG2199	diguanylate cyclase activity
HS093_RS01710	COG2203	Gaf domain
HS093_RS01715	COG3042	response to heat
HS093_RS01720	COG3189	MarR family transcriptional regulator
HS093_RS01725	COG2807	transmembrane transport
HS093_RS01730	COG2207	Transcriptional regulator
HS093_RS01745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HS093_RS01750	COG2199	diguanylate cyclase activity
HS093_RS01755	COG2199	diguanylate cyclase activity
HS093_RS01765	COG2766	serine protein kinase
HS093_RS01770	COG3713	MltA-interacting MipA family protein
HS093_RS01775	COG0656	L-ascorbic acid biosynthetic process
HS093_RS01780	COG0676	glucose-6-phosphate 1-epimerase activity
HS093_RS01785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HS093_RS01795	COG3139	Protein of unknown function (DUF1315)
HS093_RS01800	COG1063	alcohol dehydrogenase
HS093_RS01805	COG2271	Major facilitator Superfamily
HS093_RS01810	COG1063	alcohol dehydrogenase
HS093_RS01815	COG0191	fructose-bisphosphate aldolase activity
HS093_RS01820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS093_RS01825	COG0667	Aldo Keto reductase
HS093_RS01830	COG1349	DNA-binding transcription factor activity
HS093_RS01835	COG2814	Major facilitator Superfamily
HS093_RS01840	COG1335	isochorismatase
HS093_RS01845	COG0252	asparaginase activity
HS093_RS01850	COG0616	signal peptide processing
HS093_RS01855	COG0778	Nitroreductase
HS093_RS01860	COG0709	Synthesizes selenophosphate from selenide and ATP
HS093_RS01865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HS093_RS01875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HS093_RS01885	COG0494	nUDIX hydrolase
HS093_RS01890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HS093_RS01895	COG2897	thiosulfate sulfurtransferase activity
HS093_RS01900	COG4136	ATPase activity
HS093_RS01905	COG4135	transport system, permease component
HS093_RS01910	COG4134	Bacterial extracellular solute-binding protein
HS093_RS01915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HS093_RS01920	COG0398	Pfam SNARE associated Golgi protein
HS093_RS01930	COG0398	Pfam SNARE associated Golgi protein
HS093_RS01935	COG0708	Exodeoxyribonuclease III
HS093_RS01965	COG3678	ATP-independent chaperone mediated protein folding
HS093_RS01975	COG0322	excinuclease ABC activity
HS093_RS01985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS093_RS01990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HS093_RS01995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HS093_RS02000	COG1447	Phosphotransferase system cellobiose-specific component IIA
HS093_RS02005	COG2169	Transcriptional regulator
HS093_RS02005	COG1917	Cupin 2, conserved barrel domain protein
HS093_RS02010	COG1486	melibiose metabolic process
HS093_RS02020	COG0753	catalase activity
HS093_RS02040	COG1823	symporter activity
HS093_RS02045	COG1988	membrane-bound metal-dependent
HS093_RS02050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS093_RS02060	COG3001	Fructosamine kinase
HS093_RS02070	COG1105	Belongs to the carbohydrate kinase PfkB family
HS093_RS02075	COG3137	Salt-induced outer membrane protein
HS093_RS02135	COG0386	Belongs to the glutathione peroxidase family
HS093_RS02145	COG0791	NLP P60 protein
HS093_RS02150	COG2200	EAL domain
HS093_RS02160	COG4256	Hemin uptake protein
HS093_RS02165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HS093_RS02175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HS093_RS02175	COG0574	Belongs to the PEP-utilizing enzyme family
HS093_RS02180	COG0318	PFAM AMP-dependent synthetase and ligase
HS093_RS02185	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HS093_RS02190	COG0644	oxidoreductase
HS093_RS02195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HS093_RS02200	COG2086	electron transfer activity
HS093_RS02205	COG2207	Transcriptional regulator
HS093_RS02205	COG1917	Cupin 2, conserved barrel domain protein
HS093_RS02210	COG1960	acyl-CoA dehydrogenase activity
HS093_RS02215	COG4670	ketone body catabolic process
HS093_RS02230	COG2271	Major facilitator Superfamily
HS093_RS02235	COG0738	Major facilitator superfamily
HS093_RS02250	COG0628	permease
HS093_RS02255	COG0277	FAD linked oxidase domain protein
HS093_RS02255	COG0247	lactate metabolic process
HS093_RS02260	COG2050	protein possibly involved in aromatic compounds catabolism
HS093_RS02270	COG0316	Belongs to the HesB IscA family
HS093_RS02275	COG0719	Fe-S assembly protein
HS093_RS02280	COG0396	ATPase activity
HS093_RS02285	COG0719	Fe-S assembly protein
HS093_RS02300	COG1376	ErfK ybiS ycfS ynhG family protein
HS093_RS02305	COG4238	major outer membrane lipoprotein
HS093_RS02310	COG0469	pyruvate kinase activity
HS093_RS02320	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS02325	COG2414	aldehyde ferredoxin oxidoreductase
HS093_RS02335	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS02340	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HS093_RS02350	COG4529	Protein conserved in bacteria
HS093_RS02370	COG3468	outer membrane autotransporter barrel domain protein
HS093_RS02380	COG0307	riboflavin synthase, alpha
HS093_RS02385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HS093_RS02390	COG2814	Major facilitator Superfamily
HS093_RS02395	COG0583	DNA-binding transcription factor activity
HS093_RS02410	COG2814	Major facilitator Superfamily
HS093_RS02415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HS093_RS02420	COG0791	NLP P60 protein
HS093_RS02425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HS093_RS02430	COG1201	RNA secondary structure unwinding
HS093_RS02440	COG0346	lactoylglutathione lyase activity
HS093_RS02445	COG1902	pentaerythritol trinitrate reductase activity
HS093_RS02450	COG1309	transcriptional regulator
HS093_RS02455	COG3313	Fe-S protein
HS093_RS02460	COG4989	oxidoreductase activity
HS093_RS02465	COG2032	superoxide dismutase activity
HS093_RS02470	COG1289	transmembrane transporter activity
HS093_RS02475	COG1566	PFAM secretion protein HlyD family protein
HS093_RS02490	COG3133	Outer membrane lipoprotein
HS093_RS02500	COG3895	Periplasmic Protein
HS093_RS02515	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HS093_RS02520	COG0625	glutathione transferase activity
HS093_RS02525	COG3104	oligopeptide transport
HS093_RS02530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HS093_RS02540	COG4659	FMN binding
HS093_RS02580	COG0673	inositol 2-dehydrogenase activity
HS093_RS02590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HS093_RS02595	COG1263	PTS System
HS093_RS02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS02600	COG1609	Transcriptional regulator
HS093_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS02610	COG1309	transcriptional regulator
HS093_RS02615	COG3250	beta-galactosidase activity
HS093_RS02630	COG5339	Protein conserved in bacteria
HS093_RS02635	COG1482	cell wall glycoprotein biosynthetic process
HS093_RS02640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HS093_RS02640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HS093_RS02645	COG0114	fumarate hydratase activity
HS093_RS02655	COG2205	protein histidine kinase activity
HS093_RS02660	COG0745	RESPONSE REGULATOR receiver
HS093_RS02665	COG3136	membrane protein required for alginate biosynthesis
HS093_RS02675	COG0531	amino acid
HS093_RS02685	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HS093_RS02690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HS093_RS02695	COG0628	permease
HS093_RS02710	COG3591	Belongs to the peptidase S1B family
HS093_RS02725	COG2814	Major facilitator Superfamily
HS093_RS02730	COG0583	DNA-binding transcription factor activity
HS093_RS02735	COG1940	carbohydrate kinase activity
HS093_RS02740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HS093_RS02750	COG3381	protein complex oligomerization
HS093_RS02755	COG3302	dmso reductase anchor subunit
HS093_RS02760	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS02765	COG0243	molybdopterin cofactor binding
HS093_RS02770	COG0243	molybdopterin cofactor binding
HS093_RS02785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS093_RS02800	COG4948	Mandelate Racemase Muconate Lactonizing
HS093_RS02805	COG1063	alcohol dehydrogenase
HS093_RS02810	COG0477	Major facilitator Superfamily
HS093_RS02815	COG0246	Mannitol dehydrogenase
HS093_RS02825	COG1802	Transcriptional regulator
HS093_RS02830	COG4221	oxidoreductase activity
HS093_RS02835	COG0339	signal peptide processing
HS093_RS02840	COG1546	Belongs to the CinA family
HS093_RS02845	COG3111	PFAM Bacterial OB fold (BOF) protein
HS093_RS02850	COG3706	GGDEF domain
HS093_RS02860	COG2814	Major facilitator Superfamily
HS093_RS02865	COG0697	spore germination
HS093_RS02870	COG2188	Transcriptional regulator
HS093_RS02880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HS093_RS02885	COG1447	Phosphotransferase system cellobiose-specific component IIA
HS093_RS02895	COG2723	6-phospho-beta-galactosidase activity
HS093_RS02905	COG4977	sequence-specific DNA binding
HS093_RS02910	COG1846	Transcriptional regulator
HS093_RS02930	COG0583	DNA-binding transcription factor activity
HS093_RS02935	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS02940	COG2066	Belongs to the glutaminase family
HS093_RS02950	COG2199	diguanylate cyclase activity
HS093_RS02960	COG3781	membrane
HS093_RS03010	COG2911	Protein conserved in bacteria
HS093_RS03010	COG3210	domain, Protein
HS093_RS03015	COG1396	sequence-specific DNA binding
HS093_RS03020	COG3550	peptidyl-serine autophosphorylation
HS093_RS03030	COG3539	Fimbrial protein
HS093_RS03040	COG3188	usher protein
HS093_RS03045	COG3539	Fimbrial protein
HS093_RS03050	COG3539	Fimbrial protein
HS093_RS03055	COG3539	Fimbrial protein
HS093_RS03060	COG0243	molybdopterin cofactor binding
HS093_RS03075	COG3119	arylsulfatase activity
HS093_RS03080	COG0641	radical SAM
HS093_RS03090	COG4178	(ABC) transporter
HS093_RS03095	COG4771	TonB-dependent receptor
HS093_RS03100	COG0612	Peptidase, M16
HS093_RS03105	COG0076	glutamate decarboxylase activity
HS093_RS03110	COG0531	amino acid
HS093_RS03115	COG1649	PFAM Uncharacterised BCR, COG1649
HS093_RS03125	COG2199	diguanylate cyclase activity
HS093_RS03125	COG2202	Pas domain
HS093_RS03125	COG2200	EAL domain
HS093_RS03130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HS093_RS03135	COG0747	negative chemotaxis
HS093_RS03140	COG0601	transmembrane transport
HS093_RS03145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HS093_RS03150	COG0444	Belongs to the ABC transporter superfamily
HS093_RS03155	COG4608	Belongs to the ABC transporter superfamily
HS093_RS03160	COG1764	response to oxidative stress
HS093_RS03180	COG1064	alcohol dehydrogenase
HS093_RS03185	COG3093	addiction module antidote protein HigA
HS093_RS03190	COG2864	formate dehydrogenase
HS093_RS03195	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS03205	COG0697	spore germination
HS093_RS03210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS093_RS03215	COG4886	Leucine-rich repeat (LRR) protein
HS093_RS03220	COG2223	nitrite transmembrane transporter activity
HS093_RS03225	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HS093_RS03230	COG1140	nitrate reductase beta subunit
HS093_RS03235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HS093_RS03240	COG2181	nitrate reductase activity
HS093_RS03245	COG0384	phenazine biosynthesis protein PhzF
HS093_RS03250	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HS093_RS03255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HS093_RS03275	COG3209	COG3209 Rhs family protein
HS093_RS03310	COG3209	COG3209 Rhs family protein
HS093_RS03325	COG0625	glutathione transferase activity
HS093_RS03330	COG1113	amino acid transport
HS093_RS03335	COG3391	amine dehydrogenase activity
HS093_RS03340	COG4772	TonB-dependent receptor
HS093_RS03345	COG1802	Transcriptional regulator
HS093_RS03350	COG2130	NADP-dependent
HS093_RS03355	COG1247	-acetyltransferase
HS093_RS03360	COG3238	Protein conserved in bacteria
HS093_RS03390	COG1177	transmembrane transport
HS093_RS03395	COG1176	ABC-type spermidine putrescine transport system, permease component I
HS093_RS03400	COG3842	ATPase activity
HS093_RS03405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HS093_RS03410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HS093_RS03415	COG1598	PFAM Uncharacterised protein family UPF0150
HS093_RS03430	COG0826	peptidase U32
HS093_RS03435	COG1396	sequence-specific DNA binding
HS093_RS03440	COG3135	benzoate transporter
HS093_RS03445	COG0675	Transposase, IS605 OrfB family
HS093_RS03460	COG0500	methyltransferase
HS093_RS03465	COG1275	C4-dicarboxylate transporter malic acid transport protein
HS093_RS03470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HS093_RS03475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS093_RS03480	COG2841	Protein conserved in bacteria
HS093_RS03490	COG5383	Protein conserved in bacteria
HS093_RS03495	COG0583	DNA-binding transcription factor activity
HS093_RS03500	COG0840	transmembrane signaling receptor activity
HS093_RS03515	COG3038	cytochrome b561
HS093_RS03520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HS093_RS03525	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS03530	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HS093_RS03535	COG1643	Atp-dependent helicase
HS093_RS03545	COG0671	phosphoesterase, PA-phosphatase related
HS093_RS03545	COG2453	phosphatase
HS093_RS03550	COG2267	carboxylic ester hydrolase activity
HS093_RS03555	COG4589	Belongs to the CDS family
HS093_RS03560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HS093_RS03570	COG0667	Aldo Keto reductase
HS093_RS03575	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HS093_RS03580	COG3327	negative regulation of DNA-templated transcription, initiation
HS093_RS03585	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HS093_RS03590	COG0183	Belongs to the thiolase family
HS093_RS03595	COG2050	protein possibly involved in aromatic compounds catabolism
HS093_RS03600	COG1250	3-hydroxyacyl-CoA dehydrogenase
HS093_RS03605	COG1024	Enoyl-CoA hydratase
HS093_RS03610	COG1024	Enoyl-CoA hydratase
HS093_RS03615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS093_RS03620	COG2151	metal-sulfur cluster biosynthetic enzyme
HS093_RS03625	COG3396	Phenylacetate-CoA oxygenase
HS093_RS03630	COG3460	Phenylacetate-CoA oxygenase
HS093_RS03635	COG3396	Phenylacetate-CoA oxygenase
HS093_RS03640	COG2030	dehydratase
HS093_RS03640	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS03645	COG3733	amine oxidase
HS093_RS03650	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS03655	COG2207	Transcriptional regulator
HS093_RS03660	COG3784	Protein of unknown function (DUF1318)
HS093_RS03670	COG2911	Protein conserved in bacteria
HS093_RS03675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HS093_RS03680	COG3187	Heat shock protein
HS093_RS03685	COG3042	response to heat
HS093_RS03690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HS093_RS03690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HS093_RS03690	COG1013	pyruvate-flavodoxin oxidoreductase activity
HS093_RS03690	COG0674	pyruvate-flavodoxin oxidoreductase activity
HS093_RS03695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS093_RS03700	COG0589	response to stress
HS093_RS03710	COG0513	Belongs to the DEAD box helicase family
HS093_RS03720	COG3706	GGDEF domain
HS093_RS03725	COG2840	Smr protein MutS2
HS093_RS03730	COG0583	DNA-binding transcription factor activity
HS093_RS03735	COG1473	amidohydrolase
HS093_RS03740	COG1473	amidohydrolase
HS093_RS03745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HS093_RS03750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HS093_RS03755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HS093_RS03760	COG0589	response to stress
HS093_RS03765	COG3182	Iron-regulated membrane protein
HS093_RS03770	COG0668	transmembrane transport
HS093_RS03775	COG4166	transmembrane transport
HS093_RS03780	COG0583	DNA-binding transcription factor activity
HS093_RS03785	COG1073	alpha beta
HS093_RS03790	COG1073	alpha beta
HS093_RS03795	COG0702	epimerase
HS093_RS03800	COG2866	Carboxypeptidase
HS093_RS03805	COG4948	Mandelate Racemase Muconate Lactonizing
HS093_RS03810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HS093_RS03815	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HS093_RS03825	COG3106	COG3106 Predicted ATPase
HS093_RS03830	COG1609	Transcriptional regulator
HS093_RS03840	COG3842	ATPase activity
HS093_RS03845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS093_RS03850	COG1554	hydrolase, family 65, central catalytic
HS093_RS03855	COG0673	inositol 2-dehydrogenase activity
HS093_RS03860	COG1082	Xylose isomerase domain protein TIM barrel
HS093_RS03865	COG1063	alcohol dehydrogenase
HS093_RS03870	COG0395	ABC-type sugar transport system, permease component
HS093_RS03875	COG1175	transmembrane transport
HS093_RS03880	COG1653	transport
HS093_RS03885	COG0366	Alpha amylase catalytic
HS093_RS03890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HS093_RS03900	COG1983	PspC domain protein
HS093_RS03910	COG1842	Phage shock protein A
HS093_RS03915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HS093_RS03920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HS093_RS03925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HS093_RS03930	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS03935	COG1396	sequence-specific DNA binding
HS093_RS03935	COG1917	Cupin 2, conserved barrel domain protein
HS093_RS03940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HS093_RS03945	COG0174	glutamine synthetase
HS093_RS03955	COG0531	amino acid
HS093_RS03965	COG4166	transmembrane transport
HS093_RS03970	COG4168	peptide transport system, permease
HS093_RS03975	COG4171	peptide transport system, permease
HS093_RS03980	COG4172	Belongs to the ABC transporter superfamily
HS093_RS03985	COG4172	Belongs to the ABC transporter superfamily
HS093_RS03990	COG2852	Protein conserved in bacteria
HS093_RS03995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HS093_RS04000	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HS093_RS04000	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HS093_RS04015	COG5001	Diguanylate cyclase
HS093_RS04025	COG1349	DNA-binding transcription factor activity
HS093_RS04035	COG0023	Translation Initiation Factor
HS093_RS04045	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HS093_RS04050	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HS093_RS04055	COG0671	phosphoesterase, PA-phosphatase related
HS093_RS04065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HS093_RS04085	COG0583	DNA-binding transcription factor activity
HS093_RS04090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HS093_RS04100	COG0616	signal peptide processing
HS093_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS04110	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HS093_RS04115	COG1187	pseudouridine synthase activity
HS093_RS04120	COG0009	L-threonylcarbamoyladenylate synthase
HS093_RS04125	COG0613	PHP domain protein
HS093_RS04135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HS093_RS04140	COG0512	Glutamine amidotransferase of anthranilate synthase
HS093_RS04140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HS093_RS04145	COG0135	phosphoribosylanthranilate isomerase activity
HS093_RS04145	COG0134	indole-3-glycerol-phosphate synthase activity
HS093_RS04160	COG3729	General stress protein
HS093_RS04165	COG3685	Protein conserved in bacteria
HS093_RS04170	COG3685	Protein conserved in bacteria
HS093_RS04175	COG3047	cAMP biosynthetic process
HS093_RS04195	COG1607	acyl-coa hydrolase
HS093_RS04200	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HS093_RS04205	COG2350	Protein conserved in bacteria
HS093_RS04210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HS093_RS04230	COG4608	Belongs to the ABC transporter superfamily
HS093_RS04235	COG0444	Belongs to the ABC transporter superfamily
HS093_RS04240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HS093_RS04245	COG0601	transmembrane transport
HS093_RS04250	COG4166	transmembrane transport
HS093_RS04260	COG2095	MarC family integral membrane protein
HS093_RS04265	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS04265	COG1454	alcohol dehydrogenase
HS093_RS04270	COG1435	thymidine kinase activity
HS093_RS04280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HS093_RS04285	COG0745	RESPONSE REGULATOR receiver
HS093_RS04290	COG1752	Esterase of the alpha-beta hydrolase superfamily
HS093_RS04300	COG0788	formyltetrahydrofolate deformylase activity
HS093_RS04320	COG2181	nitrate reductase activity
HS093_RS04325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HS093_RS04330	COG1140	nitrate reductase beta subunit
HS093_RS04335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HS093_RS04340	COG2223	nitrite transmembrane transporter activity
HS093_RS04345	COG3850	Histidine kinase
HS093_RS04350	COG2197	response regulator
HS093_RS04355	COG4932	domain protein
HS093_RS04360	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HS093_RS04365	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HS093_RS04370	COG4572	Cation transport regulator
HS093_RS04375	COG0387	Pfam Sodium calcium exchanger
HS093_RS04400	COG2912	Transglutaminase-like superfamily
HS093_RS04405	COG3094	Invasion gene expression up-regulator, SirB
HS093_RS04410	COG2890	protein-(glutamine-N5) methyltransferase activity
HS093_RS04435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HS093_RS04440	COG0659	secondary active sulfate transmembrane transporter activity
HS093_RS04455	COG0012	GTP binding
HS093_RS04460	COG0582	viral genome integration into host DNA
HS093_RS04480	COG2826	transposase and inactivated derivatives, IS30 family
HS093_RS04520	COG5290	Psort location Cytoplasmic, score
HS093_RS04540	COG4974	Belongs to the 'phage' integrase family
HS093_RS04560	COG2003	Belongs to the UPF0758 family
HS093_RS04575	COG3423	Transcriptional regulator
HS093_RS04605	COG3335	DDE superfamily endonuclease
HS093_RS04625	COG3468	outer membrane autotransporter barrel domain protein
HS093_RS04630	COG3284	Transcriptional regulator
HS093_RS04635	COG2376	Dihydroxyacetone kinase
HS093_RS04640	COG1461	Dihydroxyacetone kinase
HS093_RS04645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HS093_RS04645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS04645	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HS093_RS04665	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HS093_RS04675	COG1619	proteins homologs of microcin C7 resistance protein MccF
HS093_RS04685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HS093_RS04695	COG2719	SpoVR family
HS093_RS04715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HS093_RS04720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HS093_RS04735	COG0179	Fumarylacetoacetate (FAA) hydrolase
HS093_RS04760	COG2894	cell division
HS093_RS04815	COG2200	EAL domain
HS093_RS04840	COG2200	EAL domain
HS093_RS04845	COG0789	Transcriptional regulator
HS093_RS04850	COG5562	phage envelope protein
HS093_RS04870	COG0538	isocitrate dehydrogenase activity
HS093_RS04875	COG1187	pseudouridine synthase activity
HS093_RS04895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HS093_RS04905	COG2205	protein histidine kinase activity
HS093_RS04910	COG2850	peptidyl-arginine hydroxylation
HS093_RS04920	COG3842	ATPase activity
HS093_RS04930	COG1177	transmembrane transport
HS093_RS04935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HS093_RS04945	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HS093_RS04950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HS093_RS04960	COG4591	ABC-type transport system involved in lipoprotein release permease component
HS093_RS04965	COG1136	(ABC) transporter
HS093_RS04970	COG4591	ABC-type transport system involved in lipoprotein release permease component
HS093_RS04975	COG4763	Acyl-transferase
HS093_RS04980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HS093_RS04985	COG1376	ErfK ybiS ycfS ynhG family protein
HS093_RS04985	COG1388	LysM domain
HS093_RS04995	COG1309	transcriptional regulator
HS093_RS05000	COG3134	Outer membrane lipoprotein
HS093_RS05005	COG1252	NADH dehydrogenase
HS093_RS05025	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HS093_RS05030	COG5633	Lipoprotein
HS093_RS05035	COG0537	adenosine 5'-monophosphoramidase activity
HS093_RS05040	COG4773	Receptor
HS093_RS05045	COG1263	PTS System
HS093_RS05045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS05050	COG0084	hydrolase, TatD family'
HS093_RS05055	COG0470	DNA polymerase III
HS093_RS05065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HS093_RS05070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HS093_RS05075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HS093_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS05090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HS093_RS05110	COG1399	metal-binding, possibly nucleic acid-binding protein
HS093_RS05115	COG0424	maF-like protein
HS093_RS05120	COG0564	pseudouridine synthase activity
HS093_RS05125	COG1530	ribonuclease E activity
HS093_RS05130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HS093_RS05135	COG1256	bacterial-type flagellum assembly
HS093_RS05140	COG1705	Flagellar rod assembly protein muramidase FlgJ
HS093_RS05140	COG3951	Flagellar rod assembly protein muramidase FlgJ
HS093_RS05155	COG4786	Flagellar basal body rod
HS093_RS05160	COG4787	bacterial-type flagellum-dependent cell motility
HS093_RS05165	COG1749	Flagellar hook protein flgE
HS093_RS05170	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HS093_RS05175	COG1558	bacterial-type flagellum-dependent cell motility
HS093_RS05180	COG1815	bacterial-type flagellum-dependent cell motility
HS093_RS05185	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HS093_RS05190	COG2747	anti-sigma28 factor FlgM
HS093_RS05195	COG3418	PFAM FlgN family protein
HS093_RS05200	COG0728	peptidoglycan biosynthetic process
HS093_RS05205	COG0673	inositol 2-dehydrogenase activity
HS093_RS05215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS093_RS05225	COG2999	glutathione oxidoreductase activity
HS093_RS05260	COG3038	cytochrome b561
HS093_RS05265	COG2353	YceI-like domain
HS093_RS05275	COG1560	Kdo2-lipid A biosynthetic process
HS093_RS05290	COG5645	(Lipo)protein
HS093_RS05295	COG2943	transferase activity, transferring hexosyl groups
HS093_RS05310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HS093_RS05315	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HS093_RS05340	COG2197	response regulator
HS093_RS05355	COG1462	curli production assembly transport component CsgG
HS093_RS05365	COG3381	protein complex oligomerization
HS093_RS05400	COG3706	GGDEF domain
HS093_RS05405	COG0457	Tetratricopeptide repeat
HS093_RS05410	COG0726	polysaccharide deacetylase
HS093_RS05410	COG1649	PFAM Uncharacterised BCR, COG1649
HS093_RS05415	COG1215	transferase activity, transferring glycosyl groups
HS093_RS05420	COG3658	cytochrome
HS093_RS05425	COG1702	phosphate starvation-inducible protein PhoH
HS093_RS05430	COG2837	iron assimilation
HS093_RS05435	COG2822	iron ion transport
HS093_RS05445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HS093_RS05455	COG0506	proline dehydrogenase activity
HS093_RS05455	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HS093_RS05455	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HS093_RS05460	COG1309	transcriptional regulator
HS093_RS05495	COG2233	PERMEase
HS093_RS05500	COG3729	General stress protein
HS093_RS05540	COG0243	molybdopterin cofactor binding
HS093_RS05545	COG3005	denitrification pathway
HS093_RS05550	COG0745	RESPONSE REGULATOR receiver
HS093_RS05555	COG1879	ABC-type sugar transport system periplasmic component
HS093_RS05560	COG2205	protein histidine kinase activity
HS093_RS05560	COG2198	Histidine kinase
HS093_RS05560	COG0784	Response regulator, receiver
HS093_RS05565	COG0348	domain, Protein
HS093_RS05585	COG1278	Cold shock
HS093_RS05590	COG1278	Cold shock
HS093_RS05610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS093_RS05615	COG1596	polysaccharide export
HS093_RS05620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HS093_RS05625	COG3206	protein involved in exopolysaccharide biosynthesis
HS093_RS05625	COG0489	protein tyrosine kinase activity
HS093_RS05640	COG1294	oxidase, subunit
HS093_RS05645	COG1271	oxidase subunit
HS093_RS05650	COG1773	rubredoxin
HS093_RS05655	COG1999	signal sequence binding
HS093_RS05660	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HS093_RS05665	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HS093_RS05670	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HS093_RS05675	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HS093_RS05685	COG0670	Belongs to the BI1 family
HS093_RS05690	COG2920	part of a sulfur-relay system
HS093_RS05695	COG1254	Belongs to the acylphosphatase family
HS093_RS05710	COG1832	CoA-binding protein
HS093_RS05725	COG0210	DNA helicase
HS093_RS05730	COG3304	Inner membrane component domain
HS093_RS05735	COG1289	transmembrane transporter activity
HS093_RS05740	COG3070	regulator of competence-specific genes
HS093_RS05750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HS093_RS05750	COG2885	chlorophyll binding
HS093_RS05760	COG1067	ATP-dependent peptidase activity
HS093_RS05770	COG3130	regulation of translation
HS093_RS05775	COG3009	Protein conserved in bacteria
HS093_RS05780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HS093_RS05780	COG3008	intermembrane lipid transfer
HS093_RS05785	COG2995	paraquat-inducible protein a
HS093_RS05790	COG0488	(ABC) transporter
HS093_RS05800	COG0633	Ferredoxin
HS093_RS05800	COG3217	Mosc domain protein beta barrel domain protein
HS093_RS05815	COG3121	Chaperone
HS093_RS05820	COG3539	Fimbrial protein
HS093_RS05825	COG3539	Fimbrial protein
HS093_RS05830	COG3539	Fimbrial protein
HS093_RS05835	COG3188	usher protein
HS093_RS05840	COG3121	Chaperone
HS093_RS05845	COG3539	Fimbrial protein
HS093_RS05850	COG0431	NADPH-dependent FMN reductase
HS093_RS05855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HS093_RS05865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HS093_RS05875	COG0308	aminopeptidase N
HS093_RS05895	COG1448	Aminotransferase
HS093_RS05900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HS093_RS05905	COG3108	Peptidase M15
HS093_RS05910	COG2989	Protein conserved in bacteria
HS093_RS05920	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HS093_RS05930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HS093_RS05935	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HS093_RS05940	COG3173	Aminoglycoside phosphotransferase
HS093_RS05955	COG3214	Protein conserved in bacteria
HS093_RS05965	COG1132	(ABC) transporter
HS093_RS05970	COG2333	competence protein COMEC
HS093_RS05970	COG0658	competence protein
HS093_RS05980	COG0539	negative regulation of cytoplasmic translation
HS093_RS05990	COG0501	Belongs to the peptidase M48B family
HS093_RS06005	COG2323	membrane
HS093_RS06010	COG1944	ATP diphosphatase activity
HS093_RS06015	COG2116	formate transmembrane transporter activity
HS093_RS06020	COG1882	Formate acetyltransferase
HS093_RS06025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS093_RS06030	COG2249	NAD(P)H dehydrogenase (quinone) activity
HS093_RS06035	COG0583	DNA-binding transcription factor activity
HS093_RS06040	COG0531	amino acid
HS093_RS06050	COG1335	isochorismatase
HS093_RS06055	COG3302	dmso reductase anchor subunit
HS093_RS06060	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS06065	COG0243	molybdopterin cofactor binding
HS093_RS06075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HS093_RS06090	COG1522	sequence-specific DNA binding
HS093_RS06095	COG0492	ferredoxin-NADP+ reductase activity
HS093_RS06100	COG4988	ABC transporter
HS093_RS06105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HS093_RS06125	COG0542	response to heat
HS093_RS06135	COG1278	Cold shock
HS093_RS06140	COG1136	(ABC) transporter
HS093_RS06140	COG0577	efflux transmembrane transporter activity
HS093_RS06145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS093_RS06150	COG2990	Protein conserved in bacteria
HS093_RS06155	COG3593	DNA synthesis involved in DNA repair
HS093_RS06165	COG2431	L-lysine efflux transmembrane transporter activity
HS093_RS06175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS093_RS06180	COG0028	Belongs to the TPP enzyme family
HS093_RS06185	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HS093_RS06190	COG0702	epimerase
HS093_RS06195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HS093_RS06200	COG3023	N-Acetylmuramoyl-L-alanine amidase
HS093_RS06215	COG1126	abc transporter atp-binding protein
HS093_RS06220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS06225	COG4215	(ABC) transporter
HS093_RS06230	COG4160	amino acid transport
HS093_RS06235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS06250	COG1177	transmembrane transport
HS093_RS06255	COG1176	ABC-type spermidine putrescine transport system, permease component I
HS093_RS06260	COG3842	ATPase activity
HS093_RS06265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HS093_RS06280	COG0778	Nitroreductase
HS093_RS06290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HS093_RS06305	COG3226	Transcriptional regulator
HS093_RS06310	COG0738	Major facilitator superfamily
HS093_RS06315	COG0561	phosphatase activity
HS093_RS06325	COG2814	Major facilitator Superfamily
HS093_RS06330	COG0671	phosphoesterase, PA-phosphatase related
HS093_RS06335	COG1349	DNA-binding transcription factor activity
HS093_RS06340	COG1686	Belongs to the peptidase S11 family
HS093_RS06345	COG0625	glutathione transferase activity
HS093_RS06350	COG2133	pyrroloquinoline quinone binding
HS093_RS06365	COG2199	diguanylate cyclase activity
HS093_RS06370	COG2200	EAL domain
HS093_RS06395	COG1446	asparaginase
HS093_RS06400	COG0303	'Molybdopterin
HS093_RS06405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HS093_RS06410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HS093_RS06415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS093_RS06420	COG1882	Formate acetyltransferase
HS093_RS06425	COG0561	phosphatase activity
HS093_RS06435	COG3547	Transposase (IS116 IS110 IS902 family)
HS093_RS06440	COG0488	(ABC) transporter
HS093_RS06445	COG1376	ErfK ybiS ycfS ynhG family protein
HS093_RS06450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HS093_RS06455	COG1321	iron dependent repressor
HS093_RS06465	COG2194	sulfuric ester hydrolase activity
HS093_RS06470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HS093_RS06480	COG5006	permease, DMT superfamily
HS093_RS06490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS06495	COG0765	amino acid transport
HS093_RS06500	COG1126	abc transporter atp-binding protein
HS093_RS06505	COG0668	transmembrane transport
HS093_RS06520	COG4774	siderophore transport
HS093_RS06530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HS093_RS06540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HS093_RS06545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HS093_RS06550	COG1199	ATP-dependent helicase activity
HS093_RS06555	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HS093_RS06560	COG0513	Belongs to the DEAD box helicase family
HS093_RS06565	COG1309	transcriptional regulator
HS093_RS06575	COG1131	(ABC) transporter
HS093_RS06580	COG0842	Transport permease protein
HS093_RS06585	COG0842	Transport permease protein
HS093_RS06595	COG3568	Endonuclease Exonuclease Phosphatase
HS093_RS06600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HS093_RS06605	COG0392	lysyltransferase activity
HS093_RS06610	COG0670	Belongs to the BI1 family
HS093_RS06620	COG0670	Belongs to the BI1 family
HS093_RS06625	COG0314	molybdopterin synthase activity
HS093_RS06630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HS093_RS06640	COG0521	Mo-molybdopterin cofactor biosynthetic process
HS093_RS06650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HS093_RS06660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HS093_RS06665	COG2226	methyltransferase
HS093_RS06680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HS093_RS06685	COG1881	PFAM PEBP family protein
HS093_RS06690	COG4677	pectinesterase activity
HS093_RS06695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HS093_RS06700	COG0471	metal ion transport
HS093_RS06705	COG2828	Protein conserved in bacteria
HS093_RS06710	COG0583	DNA-binding transcription factor activity
HS093_RS06720	COG0561	phosphatase activity
HS093_RS06730	COG4149	molybdate abc transporter
HS093_RS06735	COG0725	ABC transporter, periplasmic molybdate-binding protein
HS093_RS06745	COG3585	molybdate ion transport
HS093_RS06745	COG2005	Transcriptional regulator
HS093_RS06750	COG1119	ATPase activity
HS093_RS06755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HS093_RS06760	COG1085	galactose-1-phosphate uridylyltransferase
HS093_RS06770	COG2017	converts alpha-aldose to the beta-anomer
HS093_RS06780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HS093_RS06790	COG1230	cation diffusion facilitator family transporter
HS093_RS06795	COG3201	nicotinamide mononucleotide transporter
HS093_RS06845	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HS093_RS06850	COG2885	chlorophyll binding
HS093_RS06860	COG3064	Membrane
HS093_RS06865	COG0848	biopolymer transport protein
HS093_RS06870	COG0811	peptide transport
HS093_RS06875	COG0824	Thioesterase
HS093_RS06880	COG3790	cyd operon protein YbgE
HS093_RS06885	COG4890	Cyd operon protein YbgT
HS093_RS06890	COG1294	oxidase, subunit
HS093_RS06895	COG1271	oxidase subunit
HS093_RS06900	COG0383	alpha-mannosidase activity
HS093_RS06905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS06905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS06905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS06910	COG2188	Transcriptional regulator
HS093_RS06915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS093_RS06925	COG0508	dehydrogenase complex catalyzes the overall conversion of
HS093_RS06930	COG0567	Dehydrogenase, E1 component
HS093_RS06935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HS093_RS06940	COG1053	succinate dehydrogenase
HS093_RS06945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HS093_RS06950	COG2009	succinate dehydrogenase
HS093_RS06960	COG0372	Belongs to the citrate synthase family
HS093_RS06965	COG3539	Fimbrial protein
HS093_RS06970	COG3188	usher protein
HS093_RS06975	COG3121	Chaperone
HS093_RS06980	COG3539	Fimbrial protein
HS093_RS06985	COG3180	Ammonia monooxygenase
HS093_RS07000	COG1984	allophanate hydrolase subunit 2
HS093_RS07005	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HS093_RS07010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HS093_RS07020	COG0415	Belongs to the DNA photolyase family
HS093_RS07025	COG3272	Protein of unknown function (DUF1722)
HS093_RS07055	COG3209	COG3209 Rhs family protein
HS093_RS07085	COG2205	protein histidine kinase activity
HS093_RS07090	COG0745	RESPONSE REGULATOR receiver
HS093_RS07100	COG1982	Orn Lys Arg decarboxylase major
HS093_RS07105	COG0531	amino acid
HS093_RS07110	COG0033	Phosphoglucomutase
HS093_RS07115	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HS093_RS07120	COG0596	Alpha beta hydrolase
HS093_RS07130	COG0716	FMN binding
HS093_RS07140	COG0735	belongs to the Fur family
HS093_RS07160	COG2190	(PTS) system
HS093_RS07160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS07160	COG1263	PTS System
HS093_RS07170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HS093_RS07175	COG1846	Transcriptional regulator
HS093_RS07175	COG1940	carbohydrate kinase activity
HS093_RS07180	COG0647	UMP catabolic process
HS093_RS07185	COG0367	asparagine synthase
HS093_RS07225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HS093_RS07235	COG1702	phosphate starvation-inducible protein PhoH
HS093_RS07245	COG4535	Mg2 and Co2 transporter CorC
HS093_RS07250	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HS093_RS07260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS07265	COG0765	amino acid transport
HS093_RS07270	COG0765	amino acid transport
HS093_RS07275	COG1126	abc transporter atp-binding protein
HS093_RS07285	COG0443	Heat shock 70 kDa protein
HS093_RS07290	COG2214	Heat shock protein DnaJ domain protein
HS093_RS07300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HS093_RS07305	COG2214	Heat shock protein DnaJ domain protein
HS093_RS07315	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HS093_RS07320	COG2888	peptidyl-tyrosine sulfation
HS093_RS07335	COG1466	dna polymerase III delta subunit
HS093_RS07345	COG0406	alpha-ribazole phosphatase activity
HS093_RS07350	COG0799	negative regulation of ribosome biogenesis
HS093_RS07360	COG0768	penicillin binding
HS093_RS07365	COG0772	Belongs to the SEDS family
HS093_RS07370	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HS093_RS07375	COG1686	Belongs to the peptidase S11 family
HS093_RS07390	COG0583	DNA-binding transcription factor activity
HS093_RS07400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HS093_RS07405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HS093_RS07425	COG3069	C4-dicarboxylate transmembrane transporter activity
HS093_RS07430	COG4565	transcriptional regulatory protein
HS093_RS07435	COG3290	protein histidine kinase activity
HS093_RS07440	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HS093_RS07450	COG2301	Belongs to the HpcH HpaI aldolase family
HS093_RS07455	COG3051	citrate lyase alpha subunit
HS093_RS07470	COG0471	metal ion transport
HS093_RS07475	COG3719	Belongs to the RNase T2 family
HS093_RS07480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HS093_RS07485	COG1063	alcohol dehydrogenase
HS093_RS07490	COG0589	response to stress
HS093_RS07495	COG3634	alkyl hydroperoxide reductase activity
HS093_RS07500	COG0450	alkyl hydroperoxide reductase
HS093_RS07505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HS093_RS07510	COG0583	DNA-binding transcription factor activity
HS093_RS07515	COG3969	phosphoadenosine phosphosulfate
HS093_RS07520	COG1475	DNA binding
HS093_RS07525	COG0436	Aminotransferase
HS093_RS07530	COG0371	Dehydrogenase
HS093_RS07535	COG2879	small protein
HS093_RS07540	COG1966	Carbon starvation protein
HS093_RS07545	COG2050	protein possibly involved in aromatic compounds catabolism
HS093_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS07555	COG3433	isochorismatase activity
HS093_RS07555	COG1535	isochorismatase
HS093_RS07560	COG1021	2,3-dihydroxybenzoate-AMP ligase
HS093_RS07565	COG1169	isochorismate synthase
HS093_RS07570	COG4592	Periplasmic binding protein
HS093_RS07580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS093_RS07585	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS093_RS07590	COG1120	ATPase activity
HS093_RS07595	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HS093_RS07600	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HS093_RS07600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HS093_RS07605	COG3251	PFAM MbtH domain protein
HS093_RS07610	COG2382	esterase
HS093_RS07615	COG4771	TonB-dependent receptor
HS093_RS07620	COG2977	Belongs to the P-Pant transferase superfamily
HS093_RS07645	COG2315	Protein conserved in bacteria
HS093_RS07650	COG0778	Nitroreductase
HS093_RS07655	COG0668	transmembrane transport
HS093_RS07660	COG1113	amino acid transport
HS093_RS07665	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS093_RS07670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS093_RS07675	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS093_RS07680	COG1538	Outer membrane efflux protein
HS093_RS07685	COG0745	RESPONSE REGULATOR receiver
HS093_RS07690	COG5002	protein histidine kinase activity
HS093_RS07695	COG3501	Rhs element vgr protein
HS093_RS07705	COG3209	COG3209 Rhs family protein
HS093_RS07705	COG4104	PAAR repeat-containing protein
HS093_RS07730	COG5433	transposase activity
HS093_RS07735	COG1215	transferase activity, transferring glycosyl groups
HS093_RS07740	COG4783	chaperone-mediated protein folding
HS093_RS07750	COG2207	Transcriptional regulator
HS093_RS07760	COG2197	response regulator
HS093_RS07765	COG3539	Fimbrial protein
HS093_RS07770	COG3539	Fimbrial protein
HS093_RS07775	COG3188	usher protein
HS093_RS07780	COG3121	Chaperone
HS093_RS07785	COG3539	Fimbrial protein
HS093_RS07795	COG2501	S4 domain
HS093_RS07800	COG1988	membrane-bound metal-dependent
HS093_RS07810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HS093_RS07820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HS093_RS07825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HS093_RS07830	COG0549	Belongs to the carbamate kinase family
HS093_RS07840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS093_RS07845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS093_RS07850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HS093_RS07855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HS093_RS07860	COG3257	ureidoglycine aminohydrolase activity
HS093_RS07865	COG1929	Belongs to the glycerate kinase type-1 family
HS093_RS07870	COG2233	PERMEase
HS093_RS07880	COG1953	Uracil, thiamine, allantoin
HS093_RS07885	COG2084	Dehydrogenase
HS093_RS07890	COG3622	Belongs to the hyi family
HS093_RS07895	COG3960	tartronate-semialdehyde synthase activity
HS093_RS07900	COG1414	Transcriptional regulator
HS093_RS07910	COG0583	DNA-binding transcription factor activity
HS093_RS07945	COG3209	COG3209 Rhs family protein
HS093_RS07950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HS093_RS07955	COG4181	ATPase activity
HS093_RS07960	COG2755	lipolytic protein G-D-S-L family
HS093_RS07965	COG0300	oxidoreductase activity
HS093_RS07970	COG3118	belongs to the thioredoxin family
HS093_RS07975	COG0390	transport system, permease component
HS093_RS07980	COG4619	ABC transporter
HS093_RS07985	COG0330	HflC and HflK could
HS093_RS07990	COG1585	Membrane protein implicated in regulation of membrane protease activity
HS093_RS07995	COG0789	Transcriptional regulator
HS093_RS08000	COG0531	amino acid
HS093_RS08005	COG2066	Belongs to the glutaminase family
HS093_RS08010	COG2217	Heavy metal translocating P-type atpase
HS093_RS08015	COG3093	addiction module antidote protein HigA
HS093_RS08020	COG3735	TraB family
HS093_RS08025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HS093_RS08030	COG0737	Belongs to the 5'-nucleotidase family
HS093_RS08035	COG2223	nitrite transmembrane transporter activity
HS093_RS08040	COG4651	solute:proton antiporter activity
HS093_RS08040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HS093_RS08045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS093_RS08080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HS093_RS08090	COG2832	Protein of unknown function (DUF454)
HS093_RS08095	COG3923	Primosomal replication protein n
HS093_RS08105	COG3264	Mechanosensitive ion channel
HS093_RS08105	COG1196	nuclear chromosome segregation
HS093_RS08110	COG1309	transcriptional regulator
HS093_RS08115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS093_RS08120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS093_RS08135	COG0110	maltose O-acetyltransferase activity
HS093_RS08145	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HS093_RS08150	COG5507	3-demethylubiquinone-9 3-methyltransferase
HS093_RS08160	COG3695	enzyme binding
HS093_RS08165	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HS093_RS08170	COG1946	Acyl-CoA thioesterase
HS093_RS08175	COG0004	ammonium transporteR
HS093_RS08180	COG0347	Belongs to the P(II) protein family
HS093_RS08185	COG1132	(ABC) transporter
HS093_RS08190	COG1132	(ABC) transporter
HS093_RS08195	COG1522	sequence-specific DNA binding
HS093_RS08205	COG4533	DNA binding
HS093_RS08215	COG0824	Thioesterase
HS093_RS08220	COG1555	photosystem II stabilization
HS093_RS08225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HS093_RS08230	COG0776	regulation of translation
HS093_RS08235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HS093_RS08255	COG0271	Belongs to the BolA IbaG family
HS093_RS08260	COG3056	Lipoprotein
HS093_RS08265	COG2223	nitrite transmembrane transporter activity
HS093_RS08270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HS093_RS08275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HS093_RS08280	COG1845	cytochrome c oxidase, subunit III
HS093_RS08285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HS093_RS08310	COG2814	Major facilitator Superfamily
HS093_RS08320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HS093_RS08325	COG0693	protein deglycase activity
HS093_RS08340	COG0142	geranyltranstransferase activity
HS093_RS08350	COG0667	Aldo Keto reductase
HS093_RS08355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HS093_RS08360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HS093_RS08375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HS093_RS08375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HS093_RS08385	COG4238	major outer membrane lipoprotein
HS093_RS08390	COG3248	Nucleoside-binding outer membrane protein
HS093_RS08395	COG1403	HNH endonuclease
HS093_RS08400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HS093_RS08405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HS093_RS08410	COG1862	Preprotein translocase
HS093_RS08430	COG0366	Alpha amylase catalytic
HS093_RS08435	COG1113	amino acid transport
HS093_RS08440	COG1114	Component of the transport system for branched-chain amino acids
HS093_RS08445	COG5002	protein histidine kinase activity
HS093_RS08450	COG0745	RESPONSE REGULATOR receiver
HS093_RS08455	COG0420	3'-5' exonuclease activity
HS093_RS08460	COG0419	ATPase involved in DNA repair
HS093_RS08465	COG2814	Major facilitator Superfamily
HS093_RS08470	COG1940	carbohydrate kinase activity
HS093_RS08495	COG4126	flavin adenine dinucleotide binding
HS093_RS08515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HS093_RS08520	COG3706	GGDEF domain
HS093_RS08530	COG1785	Belongs to the alkaline phosphatase family
HS093_RS08545	COG1181	Belongs to the D-alanine--D-alanine ligase family
HS093_RS08565	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HS093_RS08570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HS093_RS08575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HS093_RS08580	COG3468	outer membrane autotransporter barrel domain protein
HS093_RS08585	COG0113	porphobilinogen synthase activity
HS093_RS08590	COG2175	clavaminate synthase activity
HS093_RS08595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HS093_RS08605	COG4521	taurine ABC transporter
HS093_RS08610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HS093_RS08615	COG1215	transferase activity, transferring glycosyl groups
HS093_RS08645	COG3122	Protein conserved in bacteria
HS093_RS08650	COG2814	Major facilitator Superfamily
HS093_RS08685	COG1414	Transcriptional regulator
HS093_RS08690	COG1609	Transcriptional regulator
HS093_RS08695	COG3250	beta-galactosidase activity
HS093_RS08700	COG2223	nitrite transmembrane transporter activity
HS093_RS08705	COG2807	transmembrane transport
HS093_RS08715	COG0288	reversible hydration of carbon dioxide
HS093_RS08720	COG0583	DNA-binding transcription factor activity
HS093_RS08725	COG0402	S-adenosylhomocysteine deaminase activity
HS093_RS08730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HS093_RS08735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HS093_RS08740	COG2079	MmgE PrpD family protein
HS093_RS08745	COG0372	Belongs to the citrate synthase family
HS093_RS08750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HS093_RS08755	COG3829	transcription factor binding
HS093_RS08765	COG1280	lysine exporter protein (LysE YggA)
HS093_RS08780	COG1064	alcohol dehydrogenase
HS093_RS08790	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS093_RS08795	COG1129	ABC transporter
HS093_RS08800	COG1879	ABC-type sugar transport system periplasmic component
HS093_RS08810	COG0402	S-adenosylhomocysteine deaminase activity
HS093_RS08815	COG0549	Belongs to the carbamate kinase family
HS093_RS08820	COG1304	FMN binding
HS093_RS08825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HS093_RS08835	COG0666	response to abiotic stimulus
HS093_RS08845	COG0583	DNA-binding transcription factor activity
HS093_RS08850	COG2771	luxR family
HS093_RS08850	COG2200	EAL domain
HS093_RS08860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HS093_RS08885	COG1556	Lactate utilization protein
HS093_RS08890	COG1139	Iron-sulfur cluster binding protein
HS093_RS08895	COG0247	lactate metabolic process
HS093_RS08900	COG2207	Transcriptional regulator
HS093_RS08905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HS093_RS08915	COG3059	membrane
HS093_RS08925	COG3708	Transcriptional regulator
HS093_RS08925	COG2207	Transcriptional regulator
HS093_RS08930	COG1388	LysM domain
HS093_RS08970	COG3188	usher protein
HS093_RS08980	COG3121	Chaperone
HS093_RS08985	COG0727	PFAM Uncharacterised protein family (UPF0153)
HS093_RS08990	COG3477	response to acidic pH
HS093_RS08995	COG2080	2 iron, 2 sulfur cluster binding
HS093_RS09000	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HS093_RS09005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HS093_RS09010	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HS093_RS09015	COG0583	DNA-binding transcription factor activity
HS093_RS09035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS093_RS09055	COG2195	Cleaves the N-terminal amino acid of tripeptides
HS093_RS09060	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HS093_RS09065	COG1690	Belongs to the RtcB family
HS093_RS09070	COG0454	-acetyltransferase
HS093_RS09085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HS093_RS09090	COG1191	sigma factor activity
HS093_RS09120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HS093_RS09135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HS093_RS09160	COG4786	Flagellar basal body rod
HS093_RS09165	COG4787	bacterial-type flagellum-dependent cell motility
HS093_RS09170	COG1749	Flagellar hook protein flgE
HS093_RS09180	COG1558	bacterial-type flagellum-dependent cell motility
HS093_RS09185	COG1815	bacterial-type flagellum-dependent cell motility
HS093_RS09215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HS093_RS09235	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HS093_RS09245	COG1677	Flagellar hook-basal body complex protein FliE
HS093_RS09270	COG1987	bacterial-type flagellum assembly
HS093_RS09300	COG0791	NLP P60 protein
HS093_RS09305	COG3077	Addiction module antitoxin, RelB DinJ family
HS093_RS09310	COG3041	Addiction module toxin RelE StbE family
HS093_RS09315	COG3034	peptidoglycan biosynthetic process
HS093_RS09320	COG0121	glutamine amidotransferase
HS093_RS09330	COG1960	acyl-CoA dehydrogenase activity
HS093_RS09340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HS093_RS09385	COG5433	transposase activity
HS093_RS09395	COG3209	COG3209 Rhs family protein
HS093_RS09490	COG4104	PAAR repeat-containing protein
HS093_RS09510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HS093_RS09520	COG2226	methyltransferase
HS093_RS09530	COG1388	LysM domain
HS093_RS09530	COG0741	lytic transglycosylase activity
HS093_RS09535	COG2226	methyltransferase
HS093_RS09545	COG0583	DNA-binding transcription factor activity
HS093_RS09550	COG0656	L-ascorbic acid biosynthetic process
HS093_RS09585	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HS093_RS09590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HS093_RS09595	COG2011	ABC-type metal ion transport system permease component
HS093_RS09600	COG1464	Belongs to the NlpA lipoprotein family
HS093_RS09610	COG1720	tRNA m6t6A37 methyltransferase activity
HS093_RS09620	COG0791	NLP P60 protein
HS093_RS09625	COG3547	Transposase (IS116 IS110 IS902 family)
HS093_RS09630	COG3015	lipoprotein NlpE involved in copper resistance
HS093_RS09635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HS093_RS09640	COG4681	YaeQ
HS093_RS09650	COG4568	rho-dependent transcription termination
HS093_RS09660	COG0346	lactoylglutathione lyase activity
HS093_RS09665	COG1982	Orn Lys Arg decarboxylase major
HS093_RS09675	COG0587	DNA-directed DNA polymerase activity
HS093_RS09700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HS093_RS09705	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HS093_RS09715	COG0750	zinc metalloprotease
HS093_RS09720	COG0575	Belongs to the CDS family
HS093_RS09725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HS093_RS09730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HS093_RS09755	COG0024	Methionine aminopeptidase
HS093_RS09775	COG3835	regulator
HS093_RS09780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HS093_RS09795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HS093_RS09800	COG2860	membrane
HS093_RS09825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HS093_RS09830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HS093_RS09835	COG1120	ATPase activity
HS093_RS09840	COG4774	siderophore transport
HS093_RS09845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HS093_RS09850	COG1643	Atp-dependent helicase
HS093_RS09855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HS093_RS09865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HS093_RS09875	COG0617	tRNA 3'-terminal CCA addition
HS093_RS09880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HS093_RS09885	COG3539	Fimbrial protein
HS093_RS09890	COG3121	Chaperone
HS093_RS09895	COG3188	usher protein
HS093_RS09900	COG3539	Fimbrial protein
HS093_RS09905	COG3539	Fimbrial protein
HS093_RS09910	COG3539	Fimbrial protein
HS093_RS09915	COG3539	Fimbrial protein
HS093_RS09930	COG5464	transposase or invertase
HS093_RS09940	COG0726	polysaccharide deacetylase
HS093_RS09945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS09950	COG0842	Transport permease protein
HS093_RS09955	COG1131	(ABC) transporter
HS093_RS09960	COG0288	reversible hydration of carbon dioxide
HS093_RS09965	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HS093_RS09970	COG4993	Dehydrogenase
HS093_RS09975	COG2132	Multicopper oxidase
HS093_RS10000	COG1049	propionate catabolic process, 2-methylcitrate cycle
HS093_RS10005	COG3064	Membrane
HS093_RS10010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HS093_RS10015	COG0508	dehydrogenase complex catalyzes the overall conversion of
HS093_RS10020	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HS093_RS10025	COG2186	Transcriptional regulator
HS093_RS10030	COG1113	amino acid transport
HS093_RS10035	COG3725	Membrane protein required for beta-lactamase induction
HS093_RS10040	COG3023	N-Acetylmuramoyl-L-alanine amidase
HS093_RS10045	COG0157	Belongs to the NadC ModD family
HS093_RS10050	COG4969	Belongs to the N-Me-Phe pilin family
HS093_RS10055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HS093_RS10060	COG1459	type II secretion system
HS093_RS10075	COG0237	dephospho-CoA kinase activity
HS093_RS10090	COG0494	nUDIX hydrolase
HS093_RS10110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HS093_RS10115	COG0849	cell division
HS093_RS10120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HS093_RS10125	COG1181	Belongs to the D-alanine--D-alanine ligase family
HS093_RS10140	COG0772	Belongs to the SEDS family
HS093_RS10155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HS093_RS10160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HS093_RS10165	COG0768	penicillin binding
HS093_RS10170	COG3116	cell division
HS093_RS10185	COG1609	Transcriptional regulator
HS093_RS10195	COG0440	acetolactate synthase activity
HS093_RS10200	COG0028	Belongs to the TPP enzyme family
HS093_RS10210	COG0583	DNA-binding transcription factor activity
HS093_RS10225	COG0473	3-isopropylmalate dehydrogenase activity
HS093_RS10240	COG2814	Major facilitator Superfamily
HS093_RS10250	COG4533	DNA binding
HS093_RS10255	COG4143	(ABC) transporter
HS093_RS10260	COG1178	ABC-type Fe3 transport system permease component
HS093_RS10270	COG0586	Pfam SNARE associated Golgi protein
HS093_RS10275	COG4977	sequence-specific DNA binding
HS093_RS10290	COG0235	Class ii aldolase
HS093_RS10295	COG0417	DNA replication proofreading
HS093_RS10305	COG0564	pseudouridine synthase activity
HS093_RS10310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HS093_RS10315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HS093_RS10320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HS093_RS10360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HS093_RS10375	COG2271	Major facilitator Superfamily
HS093_RS10380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HS093_RS10385	COG0644	oxidoreductase
HS093_RS10435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HS093_RS10440	COG0505	Belongs to the CarA family
HS093_RS10460	COG1047	Peptidyl-prolyl cis-trans
HS093_RS10475	COG0196	riboflavin kinase activity
HS093_RS10505	COG0583	DNA-binding transcription factor activity
HS093_RS10510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HS093_RS10520	COG3119	arylsulfatase activity
HS093_RS10550	COG4735	regulation of single-species biofilm formation
HS093_RS10555	COG1584	GPR1 FUN34 yaaH family protein
HS093_RS10560	COG0521	Mo-molybdopterin cofactor biosynthetic process
HS093_RS10565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HS093_RS10570	COG1115	amino acid carrier protein
HS093_RS10580	COG3547	Transposase (IS116 IS110 IS902 family)
HS093_RS10590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HS093_RS10600	COG0527	aspartate kinase activity
HS093_RS10600	COG0460	homoserine dehydrogenase
HS093_RS10610	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HS093_RS10620	COG0745	RESPONSE REGULATOR receiver
HS093_RS10625	COG4452	Inner membrane protein CreD
HS093_RS10630	COG2205	protein histidine kinase activity
HS093_RS10635	COG0745	RESPONSE REGULATOR receiver
HS093_RS10640	COG3045	CreA protein
HS093_RS10645	COG2207	Transcriptional regulator
HS093_RS10645	COG3708	Transcriptional regulator
HS093_RS10665	COG0741	lytic transglycosylase activity
HS093_RS10670	COG0488	(ABC) transporter
HS093_RS10675	COG3172	ATPase kinase involved in NAD metabolism
HS093_RS10675	COG1056	cytidyltransferase-related domain
HS093_RS10680	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HS093_RS10685	COG0560	Phosphoserine phosphatase
HS093_RS10690	COG3726	membrane protein affecting hemolysin expression
HS093_RS10725	COG1328	CTP reductase activity
HS093_RS10730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS093_RS10735	COG0084	hydrolase, TatD family'
HS093_RS10740	COG4667	esterase of the alpha-beta hydrolase superfamily
HS093_RS10750	COG2823	Periplasmic or secreted lipoprotein
HS093_RS10760	COG1011	Hydrolase
HS093_RS10765	COG0456	acetyltransferase
HS093_RS10770	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HS093_RS10800	COG4114	ferric iron reductase
HS093_RS10805	COG2197	response regulator
HS093_RS10810	COG2197	response regulator
HS093_RS10815	COG2966	Psort location CytoplasmicMembrane, score
HS093_RS10830	COG1484	DNA-dependent DNA replication
HS093_RS10845	COG1063	alcohol dehydrogenase
HS093_RS10850	COG1802	Transcriptional regulator
HS093_RS10855	COG2271	Major facilitator Superfamily
HS093_RS10860	COG0840	transmembrane signaling receptor activity
HS093_RS10865	COG1846	Transcriptional regulator
HS093_RS10870	COG0179	Fumarylacetoacetate (FAA) hydrolase
HS093_RS10875	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS10880	COG3384	dioxygenase
HS093_RS10890	COG3971	2-oxopent-4-enoate hydratase activity
HS093_RS10910	COG2368	4-hydroxyphenylacetate
HS093_RS10915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HS093_RS10920	COG1966	Carbon starvation protein
HS093_RS10925	COG2879	small protein
HS093_RS10930	COG0523	cobalamin synthesis protein
HS093_RS10940	COG5457	Domain of unknown function (DUF1127)
HS093_RS10945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HS093_RS10955	COG2814	Major facilitator Superfamily
HS093_RS10960	COG2733	membrane
HS093_RS10965	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HS093_RS10970	COG1924	4 iron, 4 sulfur cluster binding
HS093_RS10985	COG0477	Major facilitator Superfamily
HS093_RS10995	COG3366	ferrous iron transmembrane transporter activity
HS093_RS11000	COG0700	Nucleoside recognition
HS093_RS11005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HS093_RS11010	COG0583	DNA-binding transcription factor activity
HS093_RS11030	COG2186	Transcriptional regulator
HS093_RS11035	COG0246	Mannitol dehydrogenase
HS093_RS11045	COG2610	gluconate transmembrane transporter activity
HS093_RS11050	COG3539	Fimbrial protein
HS093_RS11055	COG3539	Fimbrial protein
HS093_RS11060	COG3539	Fimbrial protein
HS093_RS11065	COG3188	usher protein
HS093_RS11070	COG3121	Chaperone
HS093_RS11075	COG3539	Fimbrial protein
HS093_RS11085	COG4974	Belongs to the 'phage' integrase family
HS093_RS11090	COG0582	viral genome integration into host DNA
HS093_RS11095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HS093_RS11100	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HS093_RS11125	COG1401	restriction endodeoxyribonuclease activity
HS093_RS11160	COG1064	alcohol dehydrogenase
HS093_RS11165	COG0433	COG0433 Predicted ATPase
HS093_RS11170	COG0795	lipopolysaccharide-transporting ATPase activity
HS093_RS11175	COG0795	lipopolysaccharide-transporting ATPase activity
HS093_RS11185	COG2927	DNA polymerase III (CHI subunit)
HS093_RS11190	COG0525	valine-tRNA ligase activity
HS093_RS11195	COG4269	membrane
HS093_RS11200	COG0456	acetyltransferase
HS093_RS11205	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HS093_RS11225	COG2731	YhcH YjgK YiaL family protein
HS093_RS11230	COG1309	transcriptional regulator
HS093_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS11240	COG0251	oxidation-reduction process
HS093_RS11260	COG0251	oxidation-reduction process
HS093_RS11270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HS093_RS11280	COG1609	Transcriptional regulator
HS093_RS11285	COG1263	PTS System
HS093_RS11285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS11290	COG0366	Alpha amylase catalytic
HS093_RS11295	COG1328	CTP reductase activity
HS093_RS11300	COG0602	queuosine metabolic process
HS093_RS11305	COG3783	Cytochrome b(562)
HS093_RS11310	COG0312	modulator of DNA gyrase
HS093_RS11320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HS093_RS11330	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS093_RS11335	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS093_RS11340	COG1129	ABC transporter
HS093_RS11345	COG1879	ABC-type sugar transport system periplasmic component
HS093_RS11350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HS093_RS11355	COG2337	Toxic component of a toxin-antitoxin (TA) module
HS093_RS11360	COG2336	PFAM SpoVT AbrB
HS093_RS11365	COG2105	PFAM AIG2 family protein
HS093_RS11370	COG2911	Protein conserved in bacteria
HS093_RS11375	COG0729	surface antigen
HS093_RS11385	COG1253	flavin adenine dinucleotide binding
HS093_RS11395	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HS093_RS11400	COG1218	3'(2'),5'-bisphosphate nucleotidase
HS093_RS11405	COG0737	Belongs to the 5'-nucleotidase family
HS093_RS11410	COG1733	regulation of RNA biosynthetic process
HS093_RS11415	COG0702	epimerase
HS093_RS11420	COG0697	spore germination
HS093_RS11430	COG1113	amino acid transport
HS093_RS11435	COG0545	Peptidyl-prolyl cis-trans isomerase
HS093_RS11440	COG3061	Opacity-associated protein A
HS093_RS11450	COG0675	Transposase, IS605 OrfB family
HS093_RS11475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HS093_RS11495	COG3477	response to acidic pH
HS093_RS11525	COG3037	sugar-specific permease SgaT UlaA
HS093_RS11540	COG1073	alpha beta
HS093_RS11545	COG3650	response to hydrogen peroxide
HS093_RS11555	COG1960	acyl-CoA dehydrogenase activity
HS093_RS11560	COG0754	glutathionylspermidine amidase activity
HS093_RS11565	COG5463	Belongs to the UPF0441 family
HS093_RS11570	COG3766	membrane
HS093_RS11580	COG1842	Phage shock protein A
HS093_RS11585	COG3789	protein conserved in bacteria
HS093_RS11590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HS093_RS11595	COG0557	exoribonuclease II activity
HS093_RS11610	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HS093_RS11615	COG0330	HflC and HflK could
HS093_RS11620	COG0330	HflC and HflK could
HS093_RS11625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HS093_RS11645	COG0860	N-Acetylmuramoyl-L-alanine amidase
HS093_RS11650	COG0802	atpase or kinase
HS093_RS11655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HS093_RS11655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HS093_RS11660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HS093_RS11700	COG1511	domain protein
HS093_RS11700	COG3264	Mechanosensitive ion channel
HS093_RS11715	COG0531	amino acid
HS093_RS11725	COG1053	succinate dehydrogenase
HS093_RS11730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HS093_RS11745	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HS093_RS11750	COG3040	lipid binding
HS093_RS11755	COG2076	Multidrug Resistance protein
HS093_RS11760	COG5510	response to toxic substance
HS093_RS11765	COG5510	response to toxic substance
HS093_RS11775	COG1509	lysine 2,3-aminomutase activity
HS093_RS11800	COG0531	amino acid
HS093_RS11805	COG3030	protein affecting phage T7 exclusion by the F plasmid
HS093_RS11810	COG1027	Aspartate ammonia-lyase
HS093_RS11815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HS093_RS11830	COG1309	transcriptional regulator
HS093_RS11840	COG3710	Transcriptional regulator
HS093_RS11845	COG0531	amino acid
HS093_RS11850	COG1982	Orn Lys Arg decarboxylase major
HS093_RS11855	COG3104	oligopeptide transport
HS093_RS11860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HS093_RS11875	COG2388	GCN5-related N-acetyl-transferase
HS093_RS11880	COG3592	Divergent 4Fe-4S mono-cluster
HS093_RS11885	COG3290	protein histidine kinase activity
HS093_RS11890	COG4565	transcriptional regulatory protein
HS093_RS11895	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HS093_RS11900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HS093_RS11900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HS093_RS11905	COG3647	Membrane
HS093_RS11910	COG2211	Major facilitator Superfamily
HS093_RS11915	COG1486	melibiose metabolic process
HS093_RS11920	COG2169	Transcriptional regulator
HS093_RS11925	COG1982	Orn Lys Arg decarboxylase major
HS093_RS11930	COG2207	Transcriptional regulator
HS093_RS11935	COG0531	amino acid
HS093_RS11940	COG2194	sulfuric ester hydrolase activity
HS093_RS11945	COG0745	RESPONSE REGULATOR receiver
HS093_RS11950	COG0642	Histidine kinase
HS093_RS11960	COG0477	Major facilitator Superfamily
HS093_RS11975	COG2824	Alkylphosphonate utilization operon protein PhnA
HS093_RS11980	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HS093_RS11990	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HS093_RS11995	COG3639	organic phosphonate transmembrane transporter activity
HS093_RS12000	COG2188	Transcriptional regulator
HS093_RS12005	COG3624	Phosphonate C-P lyase system protein PhnG
HS093_RS12010	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HS093_RS12015	COG3626	phosphonate metabolism
HS093_RS12020	COG3627	carbon phosphorus lyase activity
HS093_RS12025	COG4107	phosphonate C-P lyase system protein PhnK
HS093_RS12030	COG4778	phosphonate C-P lyase system protein PhnL
HS093_RS12035	COG3454	Phosphonate metabolism
HS093_RS12040	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HS093_RS12045	COG0456	acetyltransferase
HS093_RS12050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HS093_RS12060	COG0698	ribose 5-phosphate isomerase
HS093_RS12065	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HS093_RS12075	COG1566	PFAM secretion protein HlyD family protein
HS093_RS12080	COG1289	transmembrane transporter activity
HS093_RS12095	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HS093_RS12100	COG1301	dicarboxylic acid transport
HS093_RS12105	COG4235	cytochrome complex assembly
HS093_RS12110	COG3088	subunit of a heme lyase
HS093_RS12115	COG1138	Cytochrome C-type biogenesis protein
HS093_RS12120	COG3301	Polysulphide reductase, NrfD
HS093_RS12125	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS12130	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HS093_RS12140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HS093_RS12145	COG3162	membrane
HS093_RS12155	COG1357	PFAM Pentapeptide repeats (8 copies)
HS093_RS12160	COG0025	NhaP-type Na H and K H
HS093_RS12165	COG2252	PERMEase
HS093_RS12170	COG0789	Transcriptional regulator
HS093_RS12175	COG2207	Transcriptional regulator
HS093_RS12180	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HS093_RS12190	COG0629	single-stranded DNA binding
HS093_RS12195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HS093_RS12200	COG2315	Protein conserved in bacteria
HS093_RS12205	COG0432	Pfam Uncharacterised protein family UPF0047
HS093_RS12210	COG3700	Belongs to the class B bacterial acid phosphatase family
HS093_RS12220	COG1448	Aminotransferase
HS093_RS12225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HS093_RS12230	COG0305	Participates in initiation and elongation during chromosome replication
HS093_RS12235	COG0604	alcohol dehydrogenase
HS093_RS12245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HS093_RS12255	COG0735	belongs to the Fur family
HS093_RS12260	COG3237	CsbD-like
HS093_RS12265	COG0534	Mate efflux family protein
HS093_RS12275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HS093_RS12310	COG3842	ATPase activity
HS093_RS12315	COG2182	Extracellular solute-binding protein
HS093_RS12320	COG1175	transmembrane transport
HS093_RS12325	COG3833	ABC-type maltose transport systems, permease component
HS093_RS12330	COG2814	Major facilitator Superfamily
HS093_RS12330	COG0477	Major facilitator Superfamily
HS093_RS12345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS093_RS12370	COG0527	aspartate kinase activity
HS093_RS12375	COG0542	response to heat
HS093_RS12380	COG3541	Predicted nucleotidyltransferase
HS093_RS12395	COG1187	pseudouridine synthase activity
HS093_RS12405	COG1283	sodium-dependent phosphate transmembrane transporter activity
HS093_RS12410	COG0646	methionine synthase
HS093_RS12410	COG1410	methionine synthase
HS093_RS12415	COG1414	Transcriptional regulator
HS093_RS12430	COG2224	Isocitrate lyase
HS093_RS12435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HS093_RS12445	COG0456	acetyltransferase
HS093_RS12475	COG0151	Belongs to the GarS family
HS093_RS12480	COG2204	response regulator
HS093_RS12485	COG4191	Histidine kinase
HS093_RS12490	COG3678	ATP-independent chaperone mediated protein folding
HS093_RS12505	COG3068	Protein conserved in bacteria
HS093_RS12540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HS093_RS12545	COG2104	thiamine diphosphate biosynthetic process
HS093_RS12555	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HS093_RS12595	COG0250	Participates in transcription elongation, termination and antitermination
HS093_RS12600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HS093_RS12635	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HS093_RS12635	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HS093_RS12685	COG1309	transcriptional regulator
HS093_RS12695	COG0583	DNA-binding transcription factor activity
HS093_RS12710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HS093_RS12725	COG2194	sulfuric ester hydrolase activity
HS093_RS12730	COG2207	Transcriptional regulator
HS093_RS12735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS12740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HS093_RS12745	COG1882	Formate acetyltransferase
HS093_RS12750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS12755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS12760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HS093_RS12760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS12760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS12765	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HS093_RS12770	COG0371	Dehydrogenase
HS093_RS12775	COG3738	Protein conserved in bacteria
HS093_RS12780	COG0697	spore germination
HS093_RS12790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HS093_RS12795	COG0527	aspartate kinase activity
HS093_RS12795	COG0460	homoserine dehydrogenase
HS093_RS12800	COG0626	cystathionine gamma-synthase activity
HS093_RS12810	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HS093_RS12825	COG3209	COG3209 Rhs family protein
HS093_RS12835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HS093_RS12840	COG1609	Transcriptional regulator
HS093_RS12845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HS093_RS12860	COG1575	Belongs to the MenA family. Type 1 subfamily
HS093_RS12875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HS093_RS12885	COG1494	fructose-1,6-bisphosphatase
HS093_RS12895	COG0589	response to stress
HS093_RS12900	COG3691	Protein conserved in bacteria
HS093_RS12905	COG3152	Membrane
HS093_RS12925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HS093_RS12930	COG3547	Transposase (IS116 IS110 IS902 family)
HS093_RS12945	COG3678	ATP-independent chaperone mediated protein folding
HS093_RS12950	COG0745	RESPONSE REGULATOR receiver
HS093_RS12955	COG2205	protein histidine kinase activity
HS093_RS12960	COG2258	MOSC domain
HS093_RS12970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HS093_RS13010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS13015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS13015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS13020	COG1363	Peptidase, m42
HS093_RS13025	COG3711	transcriptional antiterminator
HS093_RS13025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS13045	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS13050	COG2864	formate dehydrogenase
HS093_RS13060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HS093_RS13065	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HS093_RS13075	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HS093_RS13085	COG0456	acetyltransferase
HS093_RS13100	COG1011	Hydrolase
HS093_RS13105	COG1349	DNA-binding transcription factor activity
HS093_RS13110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS093_RS13115	COG2084	Dehydrogenase
HS093_RS13120	COG3684	Belongs to the aldolase LacD family
HS093_RS13125	COG2942	2-epimerase
HS093_RS13130	COG2017	converts alpha-aldose to the beta-anomer
HS093_RS13135	COG1501	Belongs to the glycosyl hydrolase 31 family
HS093_RS13140	COG2211	Major facilitator Superfamily
HS093_RS13145	COG2211	Major facilitator Superfamily
HS093_RS13150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HS093_RS13155	COG2271	Major facilitator Superfamily
HS093_RS13160	COG1082	Xylose isomerase domain protein TIM barrel
HS093_RS13165	COG2188	Transcriptional regulator
HS093_RS13170	COG1217	gtp-binding protein TYPA
HS093_RS13175	COG0174	glutamine synthetase
HS093_RS13180	COG3852	Histidine kinase
HS093_RS13185	COG2204	response regulator
HS093_RS13195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HS093_RS13210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HS093_RS13210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HS093_RS13215	COG0204	Acyl-transferase
HS093_RS13220	COG5339	Protein conserved in bacteria
HS093_RS13225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HS093_RS13230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HS093_RS13235	COG3084	Protein conserved in bacteria
HS093_RS13240	COG0746	molybdenum cofactor guanylyltransferase activity
HS093_RS13245	COG1763	Mo-molybdopterin cofactor biosynthetic process
HS093_RS13275	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HS093_RS13280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HS093_RS13285	COG1739	Uncharacterized protein family UPF0029
HS093_RS13300	COG0183	Belongs to the thiolase family
HS093_RS13305	COG0543	2 iron, 2 sulfur cluster binding
HS093_RS13310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HS093_RS13315	COG0250	Participates in transcription elongation, termination and antitermination
HS093_RS13325	COG0805	protein transport
HS093_RS13330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HS093_RS13335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HS093_RS13345	COG3165	ubiquinone biosynthetic process from chorismate
HS093_RS13355	COG1322	Protein conserved in bacteria
HS093_RS13360	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HS093_RS13365	COG0412	Dienelactone hydrolase
HS093_RS13375	COG0583	DNA-binding transcription factor activity
HS093_RS13380	COG0697	spore germination
HS093_RS13385	COG0561	phosphatase activity
HS093_RS13390	COG2267	carboxylic ester hydrolase activity
HS093_RS13395	COG1280	lysine exporter protein (LysE YggA)
HS093_RS13400	COG1280	lysine exporter protein (LysE YggA)
HS093_RS13405	COG0514	ATP-dependent DNA helicase (RecQ)
HS093_RS13410	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HS093_RS13415	COG2050	protein possibly involved in aromatic compounds catabolism
HS093_RS13420	COG2962	Rard protein
HS093_RS13445	COG0598	Magnesium transport protein CorA
HS093_RS13450	COG3698	Phosphodiester glycosidase
HS093_RS13455	COG0210	DNA helicase
HS093_RS13460	COG1011	Hydrolase
HS093_RS13470	COG3159	Protein conserved in bacteria
HS093_RS13480	COG5567	small periplasmic lipoprotein
HS093_RS13490	COG3072	Adenylate cyclase
HS093_RS13500	COG1587	Uroporphyrinogen-III synthase
HS093_RS13505	COG2959	enzyme of heme biosynthesis
HS093_RS13510	COG3071	HemY protein
HS093_RS13515	COG3119	arylsulfatase activity
HS093_RS13520	COG0641	radical SAM
HS093_RS13545	COG1113	amino acid transport
HS093_RS13565	COG2244	polysaccharide biosynthetic process
HS093_RS13570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HS093_RS13575	COG0456	acetyltransferase
HS093_RS13580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HS093_RS13585	COG1088	dTDP-glucose 4,6-dehydratase activity
HS093_RS13590	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HS093_RS13595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HS093_RS13600	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HS093_RS13605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HS093_RS13610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HS093_RS13620	COG3118	belongs to the thioredoxin family
HS093_RS13635	COG0210	DNA helicase
HS093_RS13640	COG3692	DNA binding
HS093_RS13645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HS093_RS13655	COG0583	DNA-binding transcription factor activity
HS093_RS13660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HS093_RS13670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HS093_RS13675	COG3978	acetolactate synthase activity
HS093_RS13695	COG0606	chelatase, subunit chli
HS093_RS13700	COG3085	chromosome segregation
HS093_RS13740	COG2186	Transcriptional regulator
HS093_RS13745	COG0477	Major facilitator Superfamily
HS093_RS13750	COG1609	Transcriptional regulator
HS093_RS13755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS093_RS13760	COG1879	ABC-type sugar transport system periplasmic component
HS093_RS13765	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS093_RS13770	COG1129	ABC transporter
HS093_RS13800	COG1522	sequence-specific DNA binding
HS093_RS13805	COG0716	FMN binding
HS093_RS13820	COG3312	ion transport
HS093_RS13870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HS093_RS13885	COG3188	usher protein
HS093_RS13895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HS093_RS13900	COG0573	inorganic phosphate transmembrane transporter activity
HS093_RS13905	COG0581	inorganic phosphate transmembrane transporter activity
HS093_RS13910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HS093_RS13915	COG0704	Plays a role in the regulation of phosphate uptake
HS093_RS13920	COG3711	transcriptional antiterminator
HS093_RS13925	COG1263	PTS System
HS093_RS13925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS13925	COG2190	(PTS) system
HS093_RS13930	COG2723	6-phospho-beta-galactosidase activity
HS093_RS13940	COG2382	esterase
HS093_RS13955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS093_RS13960	COG2252	PERMEase
HS093_RS13965	COG0431	NADPH-dependent FMN reductase
HS093_RS13970	COG2091	lysine biosynthetic process via aminoadipic acid
HS093_RS13985	COG0814	amino acid
HS093_RS14035	COG0592	DNA-directed DNA polymerase activity
HS093_RS14045	COG0187	DNA topoisomerase II activity
HS093_RS14050	COG3753	Protein conserved in bacteria
HS093_RS14055	COG0561	phosphatase activity
HS093_RS14065	COG2186	Transcriptional regulator
HS093_RS14070	COG3734	2-keto-3-deoxy-galactonokinase
HS093_RS14075	COG0800	Aldolase
HS093_RS14085	COG2271	Major facilitator Superfamily
HS093_RS14095	COG0823	Involved in the tonB-independent uptake of proteins
HS093_RS14100	COG5645	(Lipo)protein
HS093_RS14120	COG2188	Transcriptional regulator
HS093_RS14135	COG2207	Transcriptional regulator
HS093_RS14140	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HS093_RS14145	COG3119	arylsulfatase activity
HS093_RS14155	COG2149	membrane
HS093_RS14165	COG0641	radical SAM
HS093_RS14170	COG2814	Major facilitator Superfamily
HS093_RS14185	COG0028	Belongs to the TPP enzyme family
HS093_RS14190	COG0440	acetolactate synthase activity
HS093_RS14195	COG2197	response regulator
HS093_RS14200	COG3851	Histidine kinase
HS093_RS14205	COG2271	Major facilitator Superfamily
HS093_RS14210	COG2271	Major facilitator Superfamily
HS093_RS14220	COG2252	PERMEase
HS093_RS14240	COG1464	Belongs to the NlpA lipoprotein family
HS093_RS14245	COG0697	spore germination
HS093_RS14250	COG2814	Major facilitator Superfamily
HS093_RS14265	COG2211	Major facilitator Superfamily
HS093_RS14270	COG1501	Belongs to the glycosyl hydrolase 31 family
HS093_RS14275	COG2982	Protein involved in outer membrane biogenesis
HS093_RS14280	COG2233	PERMEase
HS093_RS14285	COG0786	glutamate:sodium symporter activity
HS093_RS14290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HS093_RS14295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HS093_RS14300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HS093_RS14310	COG0194	GDP metabolic process
HS093_RS14320	COG2860	membrane
HS093_RS14325	COG3645	SOS response
HS093_RS14330	COG1561	YicC-like family, N-terminal region
HS093_RS14355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HS093_RS14385	COG1519	Transferase
HS093_RS14390	COG0859	PFAM glycosyl transferase family 9
HS093_RS14395	COG0438	transferase activity, transferring glycosyl groups
HS093_RS14400	COG0515	serine threonine protein kinase
HS093_RS14410	COG3642	lipopolysaccharide core region biosynthetic process
HS093_RS14430	COG0859	PFAM glycosyl transferase family 9
HS093_RS14435	COG0859	PFAM glycosyl transferase family 9
HS093_RS14450	COG0156	8-amino-7-oxononanoate synthase activity
HS093_RS14460	COG1216	Glycosyl transferase, family 2
HS093_RS14465	COG2861	carbohydrate metabolic process
HS093_RS14470	COG4942	peptidase
HS093_RS14480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HS093_RS14485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HS093_RS14500	COG1045	serine acetyltransferase
HS093_RS14505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HS093_RS14515	COG2186	Transcriptional regulator
HS093_RS14520	COG1620	l-lactate permease
HS093_RS14525	COG5295	Hep Hag repeat protein
HS093_RS14545	COG3722	fumarate hydratase activity
HS093_RS14555	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS14555	COG2213	PTS system mannitol-specific
HS093_RS14565	COG1566	PFAM secretion protein HlyD family protein
HS093_RS14575	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HS093_RS14585	COG1413	lyase activity
HS093_RS14600	COG0625	glutathione transferase activity
HS093_RS14610	COG3276	selenocysteine insertion sequence binding
HS093_RS14615	COG1454	alcohol dehydrogenase
HS093_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS14635	COG1566	PFAM secretion protein HlyD family protein
HS093_RS14640	COG0583	DNA-binding transcription factor activity
HS093_RS14645	COG3713	MltA-interacting MipA family protein
HS093_RS14655	COG2211	Major facilitator Superfamily
HS093_RS14665	COG0235	Class ii aldolase
HS093_RS14670	COG3623	hexulose-6-phosphate isomerase
HS093_RS14675	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HS093_RS14680	COG1070	Carbohydrate kinase
HS093_RS14685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HS093_RS14695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HS093_RS14700	COG2731	YhcH YjgK YiaL family protein
HS093_RS14710	COG1414	Transcriptional regulator
HS093_RS14715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS14720	COG3977	Valine--pyruvate aminotransferase
HS093_RS14725	COG0366	Alpha amylase catalytic
HS093_RS14730	COG2992	FlgJ-related protein
HS093_RS14735	COG2207	Transcriptional regulator
HS093_RS14735	COG1609	Transcriptional regulator
HS093_RS14740	COG4214	carbohydrate transport
HS093_RS14745	COG1129	ABC transporter
HS093_RS14750	COG4213	ABC transporter substrate-binding protein
HS093_RS14760	COG1070	Carbohydrate kinase
HS093_RS14765	COG4682	membrane
HS093_RS14770	COG4682	membrane
HS093_RS14775	COG3274	enterobacterial common antigen metabolic process
HS093_RS14800	COG1278	Cold shock
HS093_RS14805	COG2944	sequence-specific DNA binding
HS093_RS14820	COG2885	chlorophyll binding
HS093_RS14825	COG0243	molybdopterin cofactor binding
HS093_RS14830	COG0456	acetyltransferase
HS093_RS14835	COG2818	Glycosylase
HS093_RS14840	COG5571	outer membrane autotransporter
HS093_RS14845	COG2223	nitrite transmembrane transporter activity
HS093_RS14850	COG2194	sulfuric ester hydrolase activity
HS093_RS14865	COG0747	negative chemotaxis
HS093_RS14870	COG0601	transmembrane transport
HS093_RS14875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HS093_RS14880	COG0444	Belongs to the ABC transporter superfamily
HS093_RS14885	COG4608	Belongs to the ABC transporter superfamily
HS093_RS14890	COG0814	amino acid
HS093_RS14910	COG2194	sulfuric ester hydrolase activity
HS093_RS14935	COG1215	transferase activity, transferring glycosyl groups
HS093_RS14940	COG1215	transferase activity, transferring glycosyl groups
HS093_RS14945	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HS093_RS14950	COG0457	Tetratricopeptide repeat
HS093_RS14950	COG3118	belongs to the thioredoxin family
HS093_RS14955	COG2200	EAL domain
HS093_RS14955	COG2199	diguanylate cyclase activity
HS093_RS14965	COG0612	Peptidase, M16
HS093_RS14975	COG2200	EAL domain
HS093_RS14980	COG2982	Protein involved in outer membrane biogenesis
HS093_RS14985	COG0477	Major facilitator Superfamily
HS093_RS14990	COG1295	ribonuclease BN
HS093_RS14995	COG0583	DNA-binding transcription factor activity
HS093_RS15000	COG2197	response regulator
HS093_RS15010	COG1858	cytochrome C peroxidase
HS093_RS15015	COG0076	glutamate decarboxylase activity
HS093_RS15025	COG2207	Transcriptional regulator
HS093_RS15030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS093_RS15035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS093_RS15045	COG2771	luxR family
HS093_RS15050	COG3247	response to pH
HS093_RS15065	COG1285	pathogenesis
HS093_RS15070	COG2197	response regulator
HS093_RS15075	COG3065	identical protein binding
HS093_RS15095	COG1393	Belongs to the ArsC family
HS093_RS15100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HS093_RS15105	COG0640	Transcriptional regulator
HS093_RS15115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HS093_RS15120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HS093_RS15125	COG0339	signal peptide processing
HS093_RS15135	COG3104	oligopeptide transport
HS093_RS15140	COG0589	response to stress
HS093_RS15150	COG0306	phosphate transporter
HS093_RS15155	COG2081	HI0933 family
HS093_RS15175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS093_RS15180	COG1129	ABC transporter
HS093_RS15180	COG0842	Transport permease protein
HS093_RS15185	COG0842	Transport permease protein
HS093_RS15210	COG0444	Belongs to the ABC transporter superfamily
HS093_RS15215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HS093_RS15220	COG0601	transmembrane transport
HS093_RS15225	COG0747	negative chemotaxis
HS093_RS15230	COG2091	lysine biosynthetic process via aminoadipic acid
HS093_RS15235	COG0628	permease
HS093_RS15250	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HS093_RS15265	COG3714	YhhN family
HS093_RS15275	COG3776	membrane
HS093_RS15280	COG0742	ribosomal rna small subunit methyltransferase
HS093_RS15285	COG0552	protein localization to endoplasmic reticulum
HS093_RS15290	COG2884	Cell division ATP-binding protein ftsE
HS093_RS15295	COG2177	Part of the ABC transporter FtsEX involved in
HS093_RS15300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HS093_RS15305	COG0683	leucine binding
HS093_RS15310	COG0456	acetyltransferase
HS093_RS15315	COG0683	leucine binding
HS093_RS15320	COG0559	Belongs to the binding-protein-dependent transport system permease family
HS093_RS15325	COG4177	L-phenylalanine transmembrane transporter activity
HS093_RS15330	COG0411	ABC transporter
HS093_RS15335	COG0410	ABC transporter
HS093_RS15340	COG1653	transport
HS093_RS15345	COG1175	transmembrane transport
HS093_RS15355	COG3842	ATPase activity
HS093_RS15360	COG0584	glycerophosphoryl diester phosphodiesterase
HS093_RS15370	COG0405	Gamma-glutamyltransferase
HS093_RS15390	COG3157	Type VI secretion system effector, Hcp
HS093_RS15395	COG1247	-acetyltransferase
HS093_RS15400	COG0673	inositol 2-dehydrogenase activity
HS093_RS15405	COG1741	Belongs to the pirin family
HS093_RS15410	COG1609	Transcriptional regulator
HS093_RS15415	COG3265	gluconokinase activity
HS093_RS15420	COG2610	gluconate transmembrane transporter activity
HS093_RS15425	COG0514	ATP-dependent DNA helicase (RecQ)
HS093_RS15435	COG2095	MarC family integral membrane protein
HS093_RS15440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HS093_RS15465	COG0058	SHG alpha-glucan phosphorylase activity
HS093_RS15470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HS093_RS15490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HS093_RS15505	COG1349	DNA-binding transcription factor activity
HS093_RS15510	COG4650	regulator
HS093_RS15515	COG1690	Belongs to the RtcB family
HS093_RS15530	COG0058	SHG alpha-glucan phosphorylase activity
HS093_RS15535	COG1640	4-alpha-glucanotransferase
HS093_RS15540	COG2610	gluconate transmembrane transporter activity
HS093_RS15560	COG5464	transposase or invertase
HS093_RS15570	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HS093_RS15575	COG1918	ferrous iron import across plasma membrane
HS093_RS15580	COG2183	response to ionizing radiation
HS093_RS15585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HS093_RS15605	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HS093_RS15615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HS093_RS15620	COG1011	Hydrolase
HS093_RS15630	COG0494	nUDIX hydrolase
HS093_RS15635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HS093_RS15640	COG4972	Pilus assembly protein
HS093_RS15645	COG3166	PFAM Fimbrial assembly family protein
HS093_RS15660	COG4796	Type ii and iii secretion system protein
HS093_RS15675	COG3266	domain, Protein
HS093_RS15680	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HS093_RS15685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HS093_RS15695	COG0180	Tryptophanyl-tRNA synthetase
HS093_RS15700	COG2188	Transcriptional regulator
HS093_RS15710	COG3457	Alanine racemase
HS093_RS15715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HS093_RS15720	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HS093_RS15735	COG0626	cystathionine gamma-synthase activity
HS093_RS15740	COG2188	Transcriptional regulator
HS093_RS15750	COG1082	Xylose isomerase domain protein TIM barrel
HS093_RS15755	COG2222	sugar isomerase
HS093_RS15760	COG0531	amino acid
HS093_RS15775	COG2116	formate transmembrane transporter activity
HS093_RS15780	COG2146	nitrite reductase [NAD(P)H] activity
HS093_RS15785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HS093_RS15795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HS093_RS15805	COG2184	nucleotidyltransferase activity
HS093_RS15810	COG0512	Glutamine amidotransferase of anthranilate synthase
HS093_RS15815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HS093_RS15820	COG1289	transmembrane transporter activity
HS093_RS15825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HS093_RS15830	COG1765	OsmC-like protein
HS093_RS15835	COG3954	Phosphoribulokinase
HS093_RS15845	COG0429	hydrolase of the alpha beta-hydrolase fold
HS093_RS15850	COG0488	(ABC) transporter
HS093_RS15865	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HS093_RS15870	COG1047	Peptidyl-prolyl cis-trans
HS093_RS15880	COG0545	Peptidyl-prolyl cis-trans isomerase
HS093_RS15885	COG2964	Protein conserved in bacteria
HS093_RS15955	COG0089	rRNA binding
HS093_RS16045	COG0201	protein transport
HS093_RS16085	COG0789	Transcriptional regulator
HS093_RS16090	COG3036	rescue of stalled ribosome
HS093_RS16100	COG0569	domain protein
HS093_RS16120	COG0758	DNA mediated transformation
HS093_RS16130	COG0551	DNA topoisomerase type I activity
HS093_RS16150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HS093_RS16190	COG1126	abc transporter atp-binding protein
HS093_RS16195	COG0765	amino acid transport
HS093_RS16200	COG4597	amino acid ABC transporter
HS093_RS16205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS16215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS093_RS16220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HS093_RS16225	COG1309	transcriptional regulator
HS093_RS16235	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HS093_RS16245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HS093_RS16255	COG4145	pantothenate transmembrane transporter activity
HS093_RS16260	COG3924	membrane
HS093_RS16265	COG0439	Biotin carboxylase
HS093_RS16270	COG0511	ligase activity, forming carbon-carbon bonds
HS093_RS16275	COG0604	alcohol dehydrogenase
HS093_RS16280	COG2200	EAL domain
HS093_RS16280	COG2199	diguanylate cyclase activity
HS093_RS16285	COG1077	Cell shape determining protein MreB Mrl
HS093_RS16290	COG1792	Involved in formation and maintenance of cell shape
HS093_RS16295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HS093_RS16305	COG1530	ribonuclease E activity
HS093_RS16310	COG3164	Protein of unknown function
HS093_RS16315	COG0312	modulator of DNA gyrase
HS093_RS16320	COG0583	DNA-binding transcription factor activity
HS093_RS16340	COG2732	(Barnase) inhibitor
HS093_RS16360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HS093_RS16365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HS093_RS16370	COG3105	Protein conserved in bacteria
HS093_RS16375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HS093_RS16390	COG0625	glutathione transferase activity
HS093_RS16395	COG2969	positive regulation of protein catabolic process
HS093_RS16400	COG3069	C4-dicarboxylate transmembrane transporter activity
HS093_RS16430	COG2731	YhcH YjgK YiaL family protein
HS093_RS16435	COG4804	nuclease activity
HS093_RS16440	COG0493	'glutamate synthase
HS093_RS16445	COG0067	glutamate synthase
HS093_RS16445	COG0069	glutamate synthase activity
HS093_RS16445	COG0070	glutamate synthase
HS093_RS16450	COG1242	4 iron, 4 sulfur cluster binding
HS093_RS16455	COG2198	Histidine kinase
HS093_RS16455	COG5002	protein histidine kinase activity
HS093_RS16455	COG0784	Response regulator, receiver
HS093_RS16460	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HS093_RS16470	COG0515	serine threonine protein kinase
HS093_RS16475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS16490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HS093_RS16495	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HS093_RS16500	COG1137	ATPase activity
HS093_RS16505	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HS093_RS16510	COG3117	lipopolysaccharide transmembrane transporter activity
HS093_RS16515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HS093_RS16520	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HS093_RS16520	COG0517	IMP dehydrogenase activity
HS093_RS16525	COG0530	calcium, potassium:sodium antiporter activity
HS093_RS16530	COG1127	ABC transporter
HS093_RS16535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HS093_RS16540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HS093_RS16545	COG2854	intermembrane phospholipid transfer
HS093_RS16550	COG3113	response to antibiotic
HS093_RS16555	COG5007	Belongs to the BolA IbaG family
HS093_RS16565	COG3423	Transcriptional regulator
HS093_RS16570	COG0142	geranyltranstransferase activity
HS093_RS16585	COG0697	spore germination
HS093_RS16595	COG2027	D-alanyl-D-alanine carboxypeptidase
HS093_RS16600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HS093_RS16605	COG1534	Rna-binding protein
HS093_RS16615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HS093_RS16620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HS093_RS16630	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HS093_RS16660	COG0195	Participates in both transcription termination and antitermination
HS093_RS16700	COG0513	Belongs to the DEAD box helicase family
HS093_RS16705	COG0814	amino acid
HS093_RS16710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HS093_RS16715	COG0826	peptidase U32
HS093_RS16720	COG0826	peptidase U32
HS093_RS16725	COG3154	lipid carrier protein
HS093_RS16730	COG3153	acetyltransferase
HS093_RS16745	COG0693	protein deglycase activity
HS093_RS16750	COG0702	epimerase
HS093_RS16755	COG0701	Predicted permease
HS093_RS16760	COG2823	Periplasmic or secreted lipoprotein
HS093_RS16780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HS093_RS16785	COG3539	Fimbrial protein
HS093_RS16790	COG3188	usher protein
HS093_RS16795	COG3121	Chaperone
HS093_RS16800	COG3539	Fimbrial protein
HS093_RS16805	COG0363	glucosamine-6-phosphate deaminase activity
HS093_RS16810	COG3716	PTS system mannose fructose sorbose family IID component
HS093_RS16815	COG3715	PTS system
HS093_RS16820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS16830	COG2222	sugar isomerase
HS093_RS16835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HS093_RS16840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS16845	COG3716	PTS system mannose fructose sorbose family IID component
HS093_RS16855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS16865	COG1349	DNA-binding transcription factor activity
HS093_RS16875	COG2002	toxin-antitoxin pair type II binding
HS093_RS16880	COG2721	sulfolactate sulfo-lyase activity
HS093_RS16885	COG2271	Major facilitator Superfamily
HS093_RS16895	COG2084	Dehydrogenase
HS093_RS16900	COG1929	Belongs to the glycerate kinase type-1 family
HS093_RS16925	COG0583	DNA-binding transcription factor activity
HS093_RS16930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HS093_RS16940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HS093_RS16945	COG1882	Formate acetyltransferase
HS093_RS16950	COG0251	oxidation-reduction process
HS093_RS16955	COG1760	l-serine dehydratase
HS093_RS16960	COG0814	amino acid
HS093_RS16975	COG1741	Belongs to the pirin family
HS093_RS16980	COG0583	DNA-binding transcription factor activity
HS093_RS16985	COG3152	Membrane
HS093_RS16990	COG3152	Membrane
HS093_RS16995	COG0435	Glutathione S-transferase
HS093_RS17000	COG2259	Doxx family
HS093_RS17010	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HS093_RS17015	COG4575	ribosome binding
HS093_RS17020	COG1422	Protein of unknown function (DUF1090)
HS093_RS17030	COG0586	Pfam SNARE associated Golgi protein
HS093_RS17035	COG2186	Transcriptional regulator
HS093_RS17060	COG2271	Major facilitator Superfamily
HS093_RS17070	COG2721	sulfolactate sulfo-lyase activity
HS093_RS17080	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HS093_RS17085	COG0861	Integral membrane protein TerC family
HS093_RS17090	COG0673	inositol 2-dehydrogenase activity
HS093_RS17095	COG2949	membrane
HS093_RS17100	COG1451	nucleotide metabolic process
HS093_RS17115	COG5499	transcription regulator containing HTH domain
HS093_RS17120	COG1902	pentaerythritol trinitrate reductase activity
HS093_RS17120	COG0446	pyridine nucleotide-disulphide oxidoreductase
HS093_RS17125	COG3408	Glycogen debranching enzyme
HS093_RS17125	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HS093_RS17135	COG0531	amino acid
HS093_RS17140	COG2731	YhcH YjgK YiaL family protein
HS093_RS17145	COG3250	beta-galactosidase activity
HS093_RS17150	COG1609	Transcriptional regulator
HS093_RS17155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HS093_RS17165	COG0840	transmembrane signaling receptor activity
HS093_RS17170	COG1695	Transcriptional regulator
HS093_RS17175	COG2375	cellular response to nickel ion
HS093_RS17190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HS093_RS17195	COG0358	DNA primase activity
HS093_RS17200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HS093_RS17210	COG0471	metal ion transport
HS093_RS17215	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HS093_RS17220	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HS093_RS17225	COG0583	DNA-binding transcription factor activity
HS093_RS17235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HS093_RS17250	COG4991	sh3 domain protein
HS093_RS17255	COG3025	triphosphatase activity
HS093_RS17280	COG2268	Band 7 protein
HS093_RS17285	COG1585	Membrane protein implicated in regulation of membrane protease activity
HS093_RS17295	COG3539	Fimbrial protein
HS093_RS17300	COG3121	Chaperone
HS093_RS17305	COG3188	usher protein
HS093_RS17310	COG3539	Fimbrial protein
HS093_RS17315	COG2960	long-chain fatty acid transporting porin activity
HS093_RS17335	COG3384	dioxygenase
HS093_RS17340	COG0754	glutathionylspermidine amidase activity
HS093_RS17350	COG1538	Outer membrane efflux protein
HS093_RS17355	COG0494	nUDIX hydrolase
HS093_RS17360	COG3151	Protein conserved in bacteria
HS093_RS17365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HS093_RS17370	COG3150	esterase
HS093_RS17375	COG0187	DNA topoisomerase II activity
HS093_RS17380	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HS093_RS17385	COG2249	NAD(P)H dehydrogenase (quinone) activity
HS093_RS17395	COG0642	Histidine kinase
HS093_RS17400	COG0745	RESPONSE REGULATOR receiver
HS093_RS17405	COG3111	PFAM Bacterial OB fold (BOF) protein
HS093_RS17410	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HS093_RS17415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HS093_RS17420	COG0204	Acyl-transferase
HS093_RS17425	COG2132	Multicopper oxidase
HS093_RS17430	COG1032	radical SAM domain protein
HS093_RS17435	COG4238	major outer membrane lipoprotein
HS093_RS17445	COG0656	L-ascorbic acid biosynthetic process
HS093_RS17450	COG1979	alcohol dehydrogenase
HS093_RS17455	COG2207	Transcriptional regulator
HS093_RS17460	COG0586	Pfam SNARE associated Golgi protein
HS093_RS17465	COG0626	cystathionine gamma-synthase activity
HS093_RS17470	COG0811	peptide transport
HS093_RS17475	COG0848	biopolymer transport protein
HS093_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS17490	COG0667	Aldo Keto reductase
HS093_RS17505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HS093_RS17510	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS17515	COG5557	Pfam Polysulphide reductase, NrfD
HS093_RS17520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HS093_RS17525	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HS093_RS17530	COG1773	rubredoxin
HS093_RS17535	COG0375	protein maturation
HS093_RS17540	COG0298	carbon dioxide binding
HS093_RS17545	COG0625	glutathione transferase activity
HS093_RS17550	COG0754	glutathionylspermidine amidase activity
HS093_RS17555	COG0306	phosphate transporter
HS093_RS17560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HS093_RS17565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HS093_RS17570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HS093_RS17575	COG2244	polysaccharide biosynthetic process
HS093_RS17585	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HS093_RS17590	COG0795	lipopolysaccharide-transporting ATPase activity
HS093_RS17600	COG0156	8-amino-7-oxononanoate synthase activity
HS093_RS17605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HS093_RS17615	COG0318	PFAM AMP-dependent synthetase and ligase
HS093_RS17620	COG0456	acetyltransferase
HS093_RS17625	COG2186	Transcriptional regulator
HS093_RS17630	COG0277	FAD linked oxidase domain protein
HS093_RS17635	COG0277	FAD linked oxidase domain protein
HS093_RS17640	COG0247	lactate metabolic process
HS093_RS17645	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HS093_RS17650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HS093_RS17655	COG1620	l-lactate permease
HS093_RS17660	COG3064	Membrane
HS093_RS17685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HS093_RS17690	COG1459	type II secretion system
HS093_RS17695	COG2165	general secretion pathway protein
HS093_RS17725	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HS093_RS17750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HS093_RS17785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HS093_RS17965	COG4227	nucleotidyltransferase activity
HS093_RS17990	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HS093_RS18000	COG1811	Na channel or pump
HS093_RS18005	COG1982	Orn Lys Arg decarboxylase major
HS093_RS18010	COG2211	Major facilitator Superfamily
HS093_RS18025	COG1194	a g-specific adenine glycosylase
HS093_RS18035	COG3171	Protein conserved in bacteria
HS093_RS18045	COG0252	asparaginase activity
HS093_RS18055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HS093_RS18070	COG0762	integral membrane protein
HS093_RS18075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HS093_RS18080	COG2805	Type II/IV secretion system protein
HS093_RS18095	COG0189	ligase activity
HS093_RS18100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HS093_RS18105	COG2356	endonuclease I
HS093_RS18115	COG2814	Major facilitator Superfamily
HS093_RS18135	COG1166	arginine decarboxylase activity
HS093_RS18160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS18160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS18165	COG3715	PTS system
HS093_RS18170	COG3716	PTS system mannose fructose sorbose family IID component
HS093_RS18185	COG0501	Belongs to the peptidase M48B family
HS093_RS18190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HS093_RS18195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS18200	COG2213	PTS system mannitol-specific
HS093_RS18205	COG1063	alcohol dehydrogenase
HS093_RS18210	COG1494	fructose-1,6-bisphosphatase
HS093_RS18220	COG1072	(Pantothenic acid kinase))
HS093_RS18225	COG1122	ATPase activity
HS093_RS18230	COG1122	ATPase activity
HS093_RS18260	COG0191	fructose-bisphosphate aldolase activity
HS093_RS18265	COG0668	transmembrane transport
HS093_RS18270	COG1279	arginine transmembrane transporter activity
HS093_RS18275	COG2968	Membrane
HS093_RS18280	COG0583	DNA-binding transcription factor activity
HS093_RS18285	COG0427	acetyl-CoA hydrolase
HS093_RS18290	COG1024	Enoyl-CoA hydratase
HS093_RS18295	COG1703	isobutyryl-CoA mutase activity
HS093_RS18300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HS093_RS18300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HS093_RS18320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HS093_RS18335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HS093_RS18355	COG0006	proline dipeptidase activity
HS093_RS18360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HS093_RS18365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HS093_RS18390	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS18395	COG2723	6-phospho-beta-galactosidase activity
HS093_RS18405	COG1272	protein, Hemolysin III
HS093_RS18415	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HS093_RS18425	COG0716	FMN binding
HS093_RS18430	COG4974	Belongs to the 'phage' integrase family
HS093_RS18435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HS093_RS18440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HS093_RS18470	COG2233	PERMEase
HS093_RS18475	COG0493	'glutamate synthase
HS093_RS18475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS18480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS18485	COG2252	PERMEase
HS093_RS18490	COG0402	S-adenosylhomocysteine deaminase activity
HS093_RS18495	COG2233	PERMEase
HS093_RS18500	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HS093_RS18500	COG2080	2 iron, 2 sulfur cluster binding
HS093_RS18505	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HS093_RS18510	COG0402	S-adenosylhomocysteine deaminase activity
HS093_RS18515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS18515	COG0493	'glutamate synthase
HS093_RS18520	COG2068	MobA-Related Protein
HS093_RS18525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HS093_RS18530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HS093_RS18530	COG3608	succinylglutamate desuccinylase aspartoacylase
HS093_RS18535	COG0549	Belongs to the carbamate kinase family
HS093_RS18545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HS093_RS18550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HS093_RS18555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HS093_RS18560	COG3829	transcription factor binding
HS093_RS18565	COG2080	2 iron, 2 sulfur cluster binding
HS093_RS18570	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HS093_RS18575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HS093_RS18580	COG4942	peptidase
HS093_RS18590	COG3387	PFAM Glycoside hydrolase 15-related
HS093_RS18690	COG3710	Transcriptional regulator
HS093_RS18690	COG0457	Tetratricopeptide repeat
HS093_RS18695	COG0457	Tetratricopeptide repeat
HS093_RS18720	COG3710	Transcriptional regulator
HS093_RS18725	COG2771	luxR family
HS093_RS18730	COG0814	amino acid
HS093_RS18735	COG0183	Belongs to the thiolase family
HS093_RS18745	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS18750	COG2814	Major facilitator Superfamily
HS093_RS18755	COG1794	racemase activity, acting on amino acids and derivatives
HS093_RS18760	COG0583	DNA-binding transcription factor activity
HS093_RS18770	COG1609	Transcriptional regulator
HS093_RS18785	COG0667	Aldo Keto reductase
HS093_RS18795	COG0861	Integral membrane protein TerC family
HS093_RS18810	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HS093_RS18825	COG2165	general secretion pathway protein
HS093_RS18830	COG4795	General secretion pathway protein
HS093_RS18840	COG4967	type IV pilus modification protein PilV
HS093_RS18845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HS093_RS18850	COG1025	Belongs to the peptidase M16 family
HS093_RS18855	COG1074	ATP-dependent DNA helicase activity
HS093_RS18860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HS093_RS18865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HS093_RS18865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HS093_RS18870	COG0860	N-Acetylmuramoyl-L-alanine amidase
HS093_RS18890	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HS093_RS18895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HS093_RS18900	COG2166	iron-sulfur cluster assembly
HS093_RS18905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HS093_RS18915	COG0583	DNA-binding transcription factor activity
HS093_RS18920	COG2363	Small membrane protein
HS093_RS18930	COG1349	DNA-binding transcription factor activity
HS093_RS18940	COG1070	Carbohydrate kinase
HS093_RS18950	COG0738	Major facilitator superfamily
HS093_RS18955	COG0235	Class ii aldolase
HS093_RS18960	COG1454	alcohol dehydrogenase
HS093_RS18970	COG1760	l-serine dehydratase
HS093_RS18975	COG0814	amino acid
HS093_RS18980	COG1611	Belongs to the LOG family
HS093_RS18995	COG3098	single-species biofilm formation
HS093_RS19000	COG0564	pseudouridine synthase activity
HS093_RS19005	COG0716	FMN binding
HS093_RS19010	COG2271	Major facilitator Superfamily
HS093_RS19015	COG4948	Mandelate Racemase Muconate Lactonizing
HS093_RS19020	COG4948	Mandelate Racemase Muconate Lactonizing
HS093_RS19025	COG3437	response regulator, receiver
HS093_RS19025	COG3850	Histidine kinase
HS093_RS19025	COG4999	Histidine kinase
HS093_RS19025	COG2205	protein histidine kinase activity
HS093_RS19035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HS093_RS19040	COG2336	PFAM SpoVT AbrB
HS093_RS19045	COG2337	Toxic component of a toxin-antitoxin (TA) module
HS093_RS19050	COG3956	TIGRFAM MazG family protein
HS093_RS19075	COG0602	queuosine metabolic process
HS093_RS19080	COG1070	Carbohydrate kinase
HS093_RS19085	COG2223	nitrite transmembrane transporter activity
HS093_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS19095	COG0277	FAD linked oxidase domain protein
HS093_RS19100	COG0477	Major facilitator Superfamily
HS093_RS19105	COG2086	electron transfer activity
HS093_RS19110	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HS093_RS19115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HS093_RS19120	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HS093_RS19125	COG0644	oxidoreductase
HS093_RS19130	COG0720	synthase
HS093_RS19155	COG1203	CRISPR-associated helicase, Cas3
HS093_RS19170	COG1857	crispr-associated protein
HS093_RS19185	COG1518	maintenance of DNA repeat elements
HS093_RS19190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HS093_RS19195	COG2234	aminopeptidase activity
HS093_RS19250	COG4942	peptidase
HS093_RS19250	COG1388	LysM domain
HS093_RS19255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HS093_RS19270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HS093_RS19280	COG2610	gluconate transmembrane transporter activity
HS093_RS19285	COG3622	Belongs to the hyi family
HS093_RS19290	COG0235	Class ii aldolase
HS093_RS19295	COG3395	kinase activity
HS093_RS19300	COG2084	Dehydrogenase
HS093_RS19305	COG1349	DNA-binding transcription factor activity
HS093_RS19310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HS093_RS19330	COG3604	Transcriptional regulator
HS093_RS19335	COG0309	Hydrogenase expression formation protein (HypE)
HS093_RS19340	COG0409	Hydrogenase expression formation protein
HS093_RS19345	COG0298	carbon dioxide binding
HS093_RS19350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HS093_RS19355	COG0375	protein maturation
HS093_RS19365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS19370	COG0651	ATP synthesis coupled electron transport
HS093_RS19375	COG0650	Formate hydrogenlyase subunit 4
HS093_RS19380	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HS093_RS19380	COG3261	NADH dehydrogenase
HS093_RS19385	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HS093_RS19390	COG3260	NADH ubiquinone oxidoreductase 20
HS093_RS19400	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HS093_RS19410	COG5499	transcription regulator containing HTH domain
HS093_RS19415	COG2723	6-phospho-beta-galactosidase activity
HS093_RS19420	COG1263	PTS System
HS093_RS19420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS19425	COG1609	Transcriptional regulator
HS093_RS19430	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS19435	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HS093_RS19455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HS093_RS19455	COG0517	IMP dehydrogenase activity
HS093_RS19460	COG1349	DNA-binding transcription factor activity
HS093_RS19465	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS19470	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS19480	COG3732	PTS system glucitol sorbitol-specific
HS093_RS19485	COG3730	PTS system glucitol sorbitol-specific
HS093_RS19490	COG2951	lytic endotransglycosylase activity
HS093_RS19495	COG1546	Belongs to the CinA family
HS093_RS19515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HS093_RS19545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS093_RS19550	COG1238	metal cluster binding
HS093_RS19565	COG2814	Major facilitator Superfamily
HS093_RS19570	COG1566	PFAM secretion protein HlyD family protein
HS093_RS19575	COG1846	Transcriptional regulator
HS093_RS19585	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HS093_RS19590	COG2814	Major facilitator Superfamily
HS093_RS19595	COG2113	Glycine betaine
HS093_RS19600	COG4176	ABC-type proline glycine betaine transport system permease component
HS093_RS19605	COG4175	Glycine betaine
HS093_RS19610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HS093_RS19615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HS093_RS19625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HS093_RS19630	COG4575	ribosome binding
HS093_RS19645	COG2916	Histone family protein nucleoid-structuring protein H-NS
HS093_RS19650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HS093_RS19655	COG0640	Transcriptional regulator
HS093_RS19660	COG0401	homolog of Blt101
HS093_RS19665	COG1652	LysM domain
HS093_RS19670	COG1802	Transcriptional regulator
HS093_RS19675	COG1113	amino acid transport
HS093_RS19680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HS093_RS19685	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS19690	COG0579	oxidoreductase
HS093_RS19740	COG2867	negative regulation of translational initiation
HS093_RS19750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS093_RS19755	COG0497	DNA recombination
HS093_RS19770	COG4536	flavin adenine dinucleotide binding
HS093_RS19775	COG4137	Cytochrome C assembly protein
HS093_RS19780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HS093_RS19805	COG2885	chlorophyll binding
HS093_RS19810	COG2199	diguanylate cyclase activity
HS093_RS19825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HS093_RS19830	COG0287	Prephenate dehydrogenase
HS093_RS19830	COG1605	Chorismate mutase
HS093_RS19835	COG0077	Prephenate dehydratase
HS093_RS19835	COG1605	Chorismate mutase
HS093_RS19845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HS093_RS19850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HS093_RS19855	COG0564	pseudouridine synthase activity
HS093_RS19865	COG0542	response to heat
HS093_RS19890	COG0477	Major facilitator Superfamily
HS093_RS19895	COG5544	Lipoprotein
HS093_RS19900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HS093_RS19905	COG1042	CoA-binding domain protein
HS093_RS19905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HS093_RS19905	COG0045	succinate-CoA ligase (ADP-forming) activity
HS093_RS19910	COG3148	PFAM DTW domain containing protein
HS093_RS19915	COG3118	belongs to the thioredoxin family
HS093_RS19920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HS093_RS19940	COG0583	DNA-binding transcription factor activity
HS093_RS19945	COG0513	Belongs to the DEAD box helicase family
HS093_RS19955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HS093_RS19965	COG1595	DNA-templated transcription, initiation
HS093_RS19970	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HS093_RS19975	COG3026	antisigma factor binding
HS093_RS19980	COG3086	response to oxidative stress
HS093_RS19990	COG0681	Belongs to the peptidase S26 family
HS093_RS20010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HS093_RS20025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS20030	COG1737	Transcriptional regulator
HS093_RS20035	COG0560	Phosphoserine phosphatase
HS093_RS20055	COG2205	protein histidine kinase activity
HS093_RS20060	COG3170	Tfp pilus assembly protein FimV
HS093_RS20065	COG2204	response regulator
HS093_RS20070	COG0347	Belongs to the P(II) protein family
HS093_RS20075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS093_RS20075	COG1017	nitric oxide dioxygenase activity
HS093_RS20085	COG1940	carbohydrate kinase activity
HS093_RS20090	COG0457	Tetratricopeptide repeat
HS093_RS20095	COG1879	ABC-type sugar transport system periplasmic component
HS093_RS20100	COG1129	ABC transporter
HS093_RS20105	COG1172	Belongs to the binding-protein-dependent transport system permease family
HS093_RS20110	COG1063	alcohol dehydrogenase
HS093_RS20115	COG2017	converts alpha-aldose to the beta-anomer
HS093_RS20120	COG2259	Doxx family
HS093_RS20145	COG4638	Rieske (2fe-2S)
HS093_RS20150	COG0583	DNA-binding transcription factor activity
HS093_RS20155	COG2814	Major facilitator Superfamily
HS093_RS20160	COG3711	transcriptional antiterminator
HS093_RS20165	COG1073	alpha beta
HS093_RS20170	COG0483	inositol monophosphate 1-phosphatase activity
HS093_RS20190	COG0822	iron-sulfur transferase activity
HS093_RS20210	COG0633	Ferredoxin
HS093_RS20215	COG2975	iron-sulfur cluster assembly
HS093_RS20230	COG2897	thiosulfate sulfurtransferase activity
HS093_RS20235	COG2373	Large extracellular alpha-helical protein
HS093_RS20240	COG4953	penicillin-binding protein 1C
HS093_RS20270	COG2976	Protein conserved in bacteria
HS093_RS20285	COG1645	bacterial-type flagellum-dependent swarming motility
HS093_RS20295	COG0517	IMP dehydrogenase activity
HS093_RS20295	COG0516	GMP reductase activity
HS093_RS20310	COG3133	Outer membrane lipoprotein
HS093_RS20325	COG2200	EAL domain
HS093_RS20330	COG0248	Ppx GppA phosphatase
HS093_RS20335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HS093_RS20340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HS093_RS20355	COG2233	PERMEase
HS093_RS20365	COG1393	Belongs to the ArsC family
HS093_RS20370	COG4783	chaperone-mediated protein folding
HS093_RS20375	COG0628	permease
HS093_RS20380	COG2116	formate transmembrane transporter activity
HS093_RS20385	COG3604	Transcriptional regulator
HS093_RS20400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HS093_RS20405	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HS093_RS20405	COG3261	NADH dehydrogenase
HS093_RS20410	COG0651	ATP synthesis coupled electron transport
HS093_RS20415	COG4237	Hydrogenase 4 membrane
HS093_RS20425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HS093_RS20430	COG0650	Formate hydrogenlyase subunit 4
HS093_RS20435	COG0651	ATP synthesis coupled electron transport
HS093_RS20440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS20445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HS093_RS20450	COG2716	regulation of RNA biosynthetic process
HS093_RS20460	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HS093_RS20480	COG2321	neutral zinc metallopeptidase
HS093_RS20485	COG1444	tRNA N-acetyltransferase activity
HS093_RS20490	COG0400	carboxylic ester hydrolase activity
HS093_RS20505	COG1393	Belongs to the ArsC family
HS093_RS20515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HS093_RS20520	COG3850	Histidine kinase
HS093_RS20525	COG0493	'glutamate synthase
HS093_RS20525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS20535	COG5342	invasion associated locus B
HS093_RS20540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HS093_RS20545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HS093_RS20550	COG0280	phosphate acetyltransferase
HS093_RS20550	COG0281	malic enzyme
HS093_RS20555	COG4810	utilization protein
HS093_RS20560	COG4917	ethanolamine utilization protein
HS093_RS20565	COG4766	ethanolamine catabolic process
HS093_RS20570	COG4812	Cobalamin adenosyltransferase
HS093_RS20575	COG0280	phosphate acetyltransferase
HS093_RS20580	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HS093_RS20585	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HS093_RS20590	COG1012	belongs to the aldehyde dehydrogenase family
HS093_RS20595	COG4820	ethanolamine utilization protein (EutJ)
HS093_RS20600	COG1454	alcohol dehydrogenase
HS093_RS20605	COG3192	ethanolamine utilization protein
HS093_RS20610	COG4819	ethanolamine utilization protein
HS093_RS20615	COG4303	Ethanolamine ammonia lyase large subunit
HS093_RS20625	COG4816	utilization protein
HS093_RS20630	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HS093_RS20635	COG2207	Transcriptional regulator
HS093_RS20645	COG0860	N-Acetylmuramoyl-L-alanine amidase
HS093_RS20665	COG2837	iron assimilation
HS093_RS20670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HS093_RS20675	COG1263	PTS System
HS093_RS20675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HS093_RS20690	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS20695	COG4150	thiosulfate binding
HS093_RS20700	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HS093_RS20705	COG4208	sulfate ABC transporter
HS093_RS20710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HS093_RS20715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HS093_RS20730	COG2190	(PTS) system
HS093_RS20735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HS093_RS20740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS20745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HS093_RS20765	COG3530	Putative quorum-sensing-regulated virulence factor
HS093_RS20770	COG0385	Bile acid
HS093_RS20775	COG0583	DNA-binding transcription factor activity
HS093_RS20815	COG3415	Transposase
HS093_RS20820	COG3415	Transposase
HS093_RS20835	COG2199	diguanylate cyclase activity
HS093_RS20835	COG2200	EAL domain
HS093_RS20840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HS093_RS20865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS20870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS20875	COG0006	proline dipeptidase activity
HS093_RS20880	COG1363	Peptidase, m42
HS093_RS20890	COG2207	Transcriptional regulator
HS093_RS20895	COG3279	Response regulator of the LytR AlgR family
HS093_RS20900	COG3275	phosphorelay sensor kinase activity
HS093_RS20905	COG0436	Aminotransferase
HS093_RS20915	COG1560	Kdo2-lipid A biosynthetic process
HS093_RS20940	COG0028	Belongs to the TPP enzyme family
HS093_RS20945	COG0679	Auxin Efflux Carrier
HS093_RS20950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HS093_RS20955	COG2205	protein histidine kinase activity
HS093_RS20955	COG0784	Response regulator, receiver
HS093_RS20955	COG2198	Histidine kinase
HS093_RS20955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS20960	COG2197	response regulator
HS093_RS20965	COG1566	PFAM secretion protein HlyD family protein
HS093_RS20970	COG0477	Major facilitator Superfamily
HS093_RS21010	COG2116	formate transmembrane transporter activity
HS093_RS21015	COG2853	Lipoprotein
HS093_RS21025	COG2067	long-chain fatty acid transport protein
HS093_RS21030	COG3691	Protein conserved in bacteria
HS093_RS21045	COG2062	phosphohistidine phosphatase, SixA
HS093_RS21050	COG3539	Fimbrial protein
HS093_RS21055	COG3188	usher protein
HS093_RS21060	COG3121	Chaperone
HS093_RS21065	COG3539	Fimbrial protein
HS093_RS21070	COG3539	Fimbrial protein
HS093_RS21075	COG3539	Fimbrial protein
HS093_RS21105	COG0730	response to heat
HS093_RS21110	COG3101	peptidyl-lysine hydroxylation
HS093_RS21125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HS093_RS21130	COG2814	Major facilitator Superfamily
HS093_RS21145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HS093_RS21155	COG0586	Pfam SNARE associated Golgi protein
HS093_RS21165	COG0285	dihydrofolate synthase activity
HS093_RS21170	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HS093_RS21175	COG1286	toxin biosynthetic process
HS093_RS21180	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HS093_RS21185	COG0163	prenyltransferase activity
HS093_RS21190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS21195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HS093_RS21200	COG4215	(ABC) transporter
HS093_RS21205	COG4160	amino acid transport
HS093_RS21210	COG4598	ABC transporter
HS093_RS21215	COG5464	transposase or invertase
HS093_RS21220	COG1090	epimerase
HS093_RS21225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HS093_RS21230	COG0625	glutathione transferase activity
HS093_RS21235	COG0625	glutathione transferase activity
HS093_RS21240	COG0622	Phosphoesterase
HS093_RS21245	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HS093_RS21250	COG1288	antiporter activity
HS093_RS21255	COG0280	phosphate acetyltransferase
HS093_RS21255	COG0857	belongs to the CobB CobQ family
HS093_RS21260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HS093_RS21275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HS093_RS21280	COG0471	metal ion transport
HS093_RS21280	COG0490	domain, Protein
HS093_RS21290	COG0436	Aminotransferase
HS093_RS21295	COG0583	DNA-binding transcription factor activity
HS093_RS21315	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HS093_RS21320	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HS093_RS21325	COG1034	ATP synthesis coupled electron transport
HS093_RS21340	COG0839	Belongs to the complex I subunit 6 family
HS093_RS21350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HS093_RS21355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HS093_RS21385	COG2153	protein acetylation
HS093_RS21390	COG4575	ribosome binding
HS093_RS21395	COG1169	isochorismate synthase
HS093_RS21410	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HS093_RS21420	COG0318	PFAM AMP-dependent synthetase and ligase
HS093_RS21490	COG5464	transposase or invertase
HS093_RS21495	COG0247	lactate metabolic process
HS093_RS21505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HS093_RS21510	COG2271	Major facilitator Superfamily
HS093_RS21515	COG0584	glycerophosphoryl diester phosphodiesterase
HS093_RS21525	COG3642	lipopolysaccharide core region biosynthetic process
HS093_RS21530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HS093_RS21535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HS093_RS21540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HS093_RS21545	COG3468	outer membrane autotransporter barrel domain protein
HS093_RS21555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HS093_RS21560	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HS093_RS21565	COG3234	Protein of unknown function (DUF1175)
HS093_RS21570	COG2373	Large extracellular alpha-helical protein
HS093_RS21575	COG5445	Predicted secreted protein (DUF2300)
HS093_RS21580	COG4676	Protein conserved in bacteria
HS093_RS21585	COG0784	Response regulator, receiver
HS093_RS21585	COG2205	protein histidine kinase activity
HS093_RS21590	COG2197	response regulator
HS093_RS21595	COG0642	Histidine kinase
HS093_RS21595	COG2198	Histidine kinase
HS093_RS21600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HS093_RS21605	COG1477	protein flavinylation
HS093_RS21610	COG2169	Transcriptional regulator
HS093_RS21610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HS093_RS21615	COG3145	DNA-N1-methyladenine dioxygenase activity
HS093_RS21620	COG4615	Cyclic peptide transporter
HS093_RS21640	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS21640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HS093_RS21645	COG3062	negative regulation of establishment of protein localization
HS093_RS21655	COG0437	4 iron, 4 sulfur cluster binding
HS093_RS21660	COG0348	domain, Protein
HS093_RS21665	COG3043	anaerobic respiration
HS093_RS21670	COG3005	denitrification pathway
HS093_RS21675	COG4133	protoheme IX ABC transporter activity
HS093_RS21680	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HS093_RS21685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HS093_RS21690	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HS093_RS21700	COG1138	Cytochrome C-type biogenesis protein
HS093_RS21705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HS093_RS21710	COG3088	subunit of a heme lyase
HS093_RS21710	COG4235	cytochrome complex assembly
HS093_RS21715	COG2197	response regulator
HS093_RS21730	COG3083	sulfuric ester hydrolase activity
HS093_RS21750	COG1061	Type III restriction enzyme res subunit
HS093_RS21755	COG1187	pseudouridine synthase activity
HS093_RS21760	COG2814	Major facilitator Superfamily
HS093_RS21770	COG4172	Belongs to the ABC transporter superfamily
HS093_RS21775	COG4239	(ABC) transporter, permease
HS093_RS21780	COG4174	ABC transporter (Permease)
HS093_RS21785	COG4166	transmembrane transport
HS093_RS21790	COG2200	EAL domain
HS093_RS21795	COG0791	NLP P60 protein
HS093_RS21800	COG0671	phosphoesterase, PA-phosphatase related
HS093_RS21805	COG0523	cobalamin synthesis protein
HS093_RS21810	COG0246	Mannitol dehydrogenase
HS093_RS21825	COG2814	Major facilitator Superfamily
HS093_RS21830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS21830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS21835	COG1105	Belongs to the carbohydrate kinase PfkB family
HS093_RS21840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS21840	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HS093_RS21840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HS093_RS21845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS093_RS21850	COG2313	pseudouridylate synthase activity
HS093_RS21855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HS093_RS21860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HS093_RS21870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HS093_RS21875	COG1522	sequence-specific DNA binding
HS093_RS21875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS093_RS21885	COG2855	membrane
HS093_RS21890	COG0583	DNA-binding transcription factor activity
HS093_RS21895	COG0833	amino acid
HS093_RS21900	COG4771	TonB-dependent receptor
HS093_RS21915	COG2311	Membrane
HS093_RS21920	COG1609	Transcriptional regulator
HS093_RS21925	COG1879	ABC-type sugar transport system periplasmic component
HS093_RS21930	COG1129	ABC transporter
HS093_RS21935	COG4211	Belongs to the binding-protein-dependent transport system permease family
HS093_RS21940	COG0167	dihydroorotate dehydrogenase activity
HS093_RS21940	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HS093_RS21945	COG0493	'glutamate synthase
HS093_RS21955	COG2949	membrane
HS093_RS21965	COG1346	cytolysis
HS093_RS21975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HS093_RS21990	COG1028	Short-chain dehydrogenase reductase Sdr
HS093_RS21995	COG0586	Pfam SNARE associated Golgi protein
HS093_RS22005	COG1686	Belongs to the peptidase S11 family
HS093_RS22010	COG0277	FAD linked oxidase domain protein
HS093_RS22015	COG1472	Belongs to the glycosyl hydrolase 3 family
HS093_RS22020	COG1732	Glycine betaine
HS093_RS22025	COG1174	glycine betaine transport
HS093_RS22030	COG1125	glycine betaine transport
HS093_RS22035	COG1174	glycine betaine transport
HS093_RS22045	COG0789	Transcriptional regulator
HS093_RS22050	COG3275	phosphorelay sensor kinase activity
HS093_RS22055	COG3279	Response regulator of the LytR AlgR family
HS093_RS22060	COG4807	Protein conserved in bacteria
HS093_RS22065	COG4808	Protein conserved in bacteria
HS093_RS22070	COG4715	Zinc finger, swim domain protein
HS093_RS22075	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HS093_RS22080	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HS093_RS22085	COG0714	Associated with various cellular activities
HS093_RS22095	COG3831	ATPase activity
HS093_RS22100	COG3831	ATPase activity
HS093_RS22110	COG0489	protein tyrosine kinase activity
HS093_RS22120	COG3539	Fimbrial protein
HS093_RS22125	COG3121	Chaperone
HS093_RS22130	COG3188	usher protein
HS093_RS22135	COG3539	Fimbrial protein
HS093_RS22140	COG5455	response to cobalt ion
HS093_RS22160	COG0351	phosphomethylpyrimidine kinase
HS093_RS22165	COG3757	hydrolase, family 25
HS093_RS22170	COG2188	Transcriptional regulator
HS093_RS22175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HS093_RS22180	COG1397	ADP-ribosylglycohydrolase
HS093_RS22185	COG2211	Major facilitator Superfamily
HS093_RS22190	COG1830	Aldolase
HS093_RS22205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HS093_RS22210	COG3414	Phosphotransferase system galactitol-specific IIB component
HS093_RS22215	COG3775	system Galactitol-specific IIC component
HS093_RS22220	COG1063	alcohol dehydrogenase
HS093_RS22240	COG4974	Belongs to the 'phage' integrase family
HS093_RS22315	COG0741	lytic transglycosylase activity
HS093_RS22510	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HS093_RS22545	COG2337	Toxic component of a toxin-antitoxin (TA) module
HS093_RS22555	COG2336	PFAM SpoVT AbrB
HS093_RS22590	COG0629	single-stranded DNA binding
HS093_RS22690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol