locus-tag	class	description
ECOK1_RS00010	COG0460	homoserine dehydrogenase
ECOK1_RS00010	COG0527	aspartate kinase activity
ECOK1_RS00020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ECOK1_RS00040	COG1115	amino acid carrier protein
ECOK1_RS00050	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECOK1_RS00060	COG1584	GPR1 FUN34 yaaH family protein
ECOK1_RS00065	COG4735	regulation of single-species biofilm formation
ECOK1_RS00095	COG3119	arylsulfatase activity
ECOK1_RS00110	COG0583	DNA-binding transcription factor activity
ECOK1_RS00125	COG0196	riboflavin kinase activity
ECOK1_RS00140	COG1047	Peptidyl-prolyl cis-trans
ECOK1_RS00175	COG0505	Belongs to the CarA family
ECOK1_RS00180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ECOK1_RS00245	COG0644	oxidoreductase
ECOK1_RS00250	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECOK1_RS00255	COG2271	Major facilitator Superfamily
ECOK1_RS00270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ECOK1_RS00300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ECOK1_RS00305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECOK1_RS00315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ECOK1_RS00320	COG0564	pseudouridine synthase activity
ECOK1_RS00330	COG0417	DNA replication proofreading
ECOK1_RS00335	COG0235	Class ii aldolase
ECOK1_RS00350	COG4977	sequence-specific DNA binding
ECOK1_RS00365	COG0586	Pfam SNARE associated Golgi protein
ECOK1_RS00375	COG1178	ABC-type Fe3 transport system permease component
ECOK1_RS00380	COG4143	(ABC) transporter
ECOK1_RS00420	COG0583	DNA-binding transcription factor activity
ECOK1_RS00425	COG0028	Belongs to the TPP enzyme family
ECOK1_RS00430	COG0440	acetolactate synthase activity
ECOK1_RS00440	COG1609	Transcriptional regulator
ECOK1_RS00455	COG3116	cell division
ECOK1_RS00460	COG0768	penicillin binding
ECOK1_RS00465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECOK1_RS00470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ECOK1_RS00485	COG0772	Belongs to the SEDS family
ECOK1_RS00500	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECOK1_RS00505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ECOK1_RS00510	COG0849	cell division
ECOK1_RS00515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ECOK1_RS00535	COG0494	nUDIX hydrolase
ECOK1_RS00550	COG0237	dephospho-CoA kinase activity
ECOK1_RS00560	COG1459	type II secretion system
ECOK1_RS00565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECOK1_RS00570	COG4969	Belongs to the N-Me-Phe pilin family
ECOK1_RS00580	COG0157	Belongs to the NadC ModD family
ECOK1_RS00585	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECOK1_RS00590	COG3725	Membrane protein required for beta-lactamase induction
ECOK1_RS00595	COG1113	amino acid transport
ECOK1_RS00600	COG3157	Type VI secretion system effector, Hcp
ECOK1_RS00630	COG2186	Transcriptional regulator
ECOK1_RS00635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ECOK1_RS00640	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECOK1_RS00645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECOK1_RS00650	COG3064	Membrane
ECOK1_RS00655	COG1049	propionate catabolic process, 2-methylcitrate cycle
ECOK1_RS00680	COG2132	Multicopper oxidase
ECOK1_RS00685	COG4993	Dehydrogenase
ECOK1_RS00690	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ECOK1_RS00695	COG0288	reversible hydration of carbon dioxide
ECOK1_RS00700	COG1131	(ABC) transporter
ECOK1_RS00705	COG0842	Transport permease protein
ECOK1_RS00710	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS00715	COG0726	polysaccharide deacetylase
ECOK1_RS00725	COG5464	transposase or invertase
ECOK1_RS00740	COG3539	Fimbrial protein
ECOK1_RS00745	COG3539	Fimbrial protein
ECOK1_RS00750	COG3539	Fimbrial protein
ECOK1_RS00755	COG3539	Fimbrial protein
ECOK1_RS00760	COG3188	usher protein
ECOK1_RS00765	COG3121	Chaperone
ECOK1_RS00770	COG3539	Fimbrial protein
ECOK1_RS00775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ECOK1_RS00780	COG0617	tRNA 3'-terminal CCA addition
ECOK1_RS00785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECOK1_RS00790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECOK1_RS00800	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ECOK1_RS00805	COG1643	Atp-dependent helicase
ECOK1_RS00810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ECOK1_RS00815	COG4774	siderophore transport
ECOK1_RS00820	COG1120	ATPase activity
ECOK1_RS00825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECOK1_RS00830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS00850	COG2860	membrane
ECOK1_RS00855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECOK1_RS00870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECOK1_RS00875	COG3835	regulator
ECOK1_RS00895	COG0024	Methionine aminopeptidase
ECOK1_RS00920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ECOK1_RS00925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ECOK1_RS00930	COG0575	Belongs to the CDS family
ECOK1_RS00935	COG0750	zinc metalloprotease
ECOK1_RS00945	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ECOK1_RS00975	COG0587	DNA-directed DNA polymerase activity
ECOK1_RS00990	COG0346	lactoylglutathione lyase activity
ECOK1_RS00995	COG0037	tRNA processing
ECOK1_RS01000	COG4568	rho-dependent transcription termination
ECOK1_RS01010	COG4681	YaeQ
ECOK1_RS01015	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECOK1_RS01020	COG3015	lipoprotein NlpE involved in copper resistance
ECOK1_RS01025	COG0791	NLP P60 protein
ECOK1_RS01035	COG1720	tRNA m6t6A37 methyltransferase activity
ECOK1_RS01045	COG1464	Belongs to the NlpA lipoprotein family
ECOK1_RS01050	COG2011	ABC-type metal ion transport system permease component
ECOK1_RS01055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ECOK1_RS01060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECOK1_RS01095	COG0656	L-ascorbic acid biosynthetic process
ECOK1_RS01100	COG0583	DNA-binding transcription factor activity
ECOK1_RS01110	COG2226	methyltransferase
ECOK1_RS01115	COG1388	LysM domain
ECOK1_RS01115	COG0741	lytic transglycosylase activity
ECOK1_RS01125	COG2226	methyltransferase
ECOK1_RS01135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECOK1_RS01235	COG3501	Rhs element vgr protein
ECOK1_RS01255	COG5433	transposase activity
ECOK1_RS01260	COG5433	transposase activity
ECOK1_RS01275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECOK1_RS01285	COG1960	acyl-CoA dehydrogenase activity
ECOK1_RS01295	COG0121	glutamine amidotransferase
ECOK1_RS01300	COG3034	peptidoglycan biosynthetic process
ECOK1_RS01305	COG0791	NLP P60 protein
ECOK1_RS01310	COG1943	Transposase
ECOK1_RS01330	COG2161	toxin-antitoxin pair type II binding
ECOK1_RS01340	COG0454	-acetyltransferase
ECOK1_RS01345	COG1690	Belongs to the RtcB family
ECOK1_RS01350	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECOK1_RS01355	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECOK1_RS01375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECOK1_RS01395	COG0582	viral genome integration into host DNA
ECOK1_RS01435	COG3477	response to acidic pH
ECOK1_RS01440	COG0727	PFAM Uncharacterised protein family (UPF0153)
ECOK1_RS01490	COG1902	pentaerythritol trinitrate reductase activity
ECOK1_RS01495	COG1073	alpha beta
ECOK1_RS01500	COG0583	DNA-binding transcription factor activity
ECOK1_RS01510	COG0667	Aldo Keto reductase
ECOK1_RS01515	COG0656	L-ascorbic acid biosynthetic process
ECOK1_RS01520	COG1388	LysM domain
ECOK1_RS01525	COG2207	Transcriptional regulator
ECOK1_RS01525	COG3708	Transcriptional regulator
ECOK1_RS01530	COG0656	L-ascorbic acid biosynthetic process
ECOK1_RS01535	COG3059	membrane
ECOK1_RS01545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECOK1_RS01550	COG2207	Transcriptional regulator
ECOK1_RS01555	COG0247	lactate metabolic process
ECOK1_RS01560	COG1139	Iron-sulfur cluster binding protein
ECOK1_RS01565	COG1556	Lactate utilization protein
ECOK1_RS01580	COG3468	outer membrane autotransporter barrel domain protein
ECOK1_RS01590	COG2771	luxR family
ECOK1_RS01590	COG2200	EAL domain
ECOK1_RS01595	COG0582	viral genome integration into host DNA
ECOK1_RS01620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECOK1_RS01630	COG2200	EAL domain
ECOK1_RS01630	COG2771	luxR family
ECOK1_RS01635	COG0583	DNA-binding transcription factor activity
ECOK1_RS01645	COG0666	response to abiotic stimulus
ECOK1_RS01655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECOK1_RS01660	COG1304	FMN binding
ECOK1_RS01665	COG0549	Belongs to the carbamate kinase family
ECOK1_RS01670	COG0402	S-adenosylhomocysteine deaminase activity
ECOK1_RS01680	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS01685	COG1129	ABC transporter
ECOK1_RS01690	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS01700	COG1064	alcohol dehydrogenase
ECOK1_RS01710	COG1280	lysine exporter protein (LysE YggA)
ECOK1_RS01720	COG3829	transcription factor binding
ECOK1_RS01725	COG3829	transcription factor binding
ECOK1_RS01730	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ECOK1_RS01735	COG0372	Belongs to the citrate synthase family
ECOK1_RS01740	COG2079	MmgE PrpD family protein
ECOK1_RS01745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECOK1_RS01750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ECOK1_RS01755	COG0402	S-adenosylhomocysteine deaminase activity
ECOK1_RS01760	COG0110	maltose O-acetyltransferase activity
ECOK1_RS01765	COG2223	nitrite transmembrane transporter activity
ECOK1_RS01775	COG1609	Transcriptional regulator
ECOK1_RS01780	COG3122	Protein conserved in bacteria
ECOK1_RS01810	COG1215	transferase activity, transferring glycosyl groups
ECOK1_RS01815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ECOK1_RS01820	COG4521	taurine ABC transporter
ECOK1_RS01830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECOK1_RS01835	COG2175	clavaminate synthase activity
ECOK1_RS01840	COG0113	porphobilinogen synthase activity
ECOK1_RS01845	COG3468	outer membrane autotransporter barrel domain protein
ECOK1_RS01850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECOK1_RS01855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECOK1_RS01865	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ECOK1_RS01885	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECOK1_RS01895	COG1785	Belongs to the alkaline phosphatase family
ECOK1_RS01905	COG3706	GGDEF domain
ECOK1_RS01910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ECOK1_RS01935	COG4126	flavin adenine dinucleotide binding
ECOK1_RS01955	COG1940	carbohydrate kinase activity
ECOK1_RS01960	COG2814	Major facilitator Superfamily
ECOK1_RS01965	COG0419	ATPase involved in DNA repair
ECOK1_RS01970	COG0420	3'-5' exonuclease activity
ECOK1_RS01975	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS01980	COG5002	protein histidine kinase activity
ECOK1_RS01985	COG1114	Component of the transport system for branched-chain amino acids
ECOK1_RS01990	COG1113	amino acid transport
ECOK1_RS01995	COG0366	Alpha amylase catalytic
ECOK1_RS02015	COG1862	Preprotein translocase
ECOK1_RS02020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECOK1_RS02025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECOK1_RS02030	COG1403	HNH endonuclease
ECOK1_RS02035	COG3248	Nucleoside-binding outer membrane protein
ECOK1_RS02040	COG4238	major outer membrane lipoprotein
ECOK1_RS02050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECOK1_RS02050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECOK1_RS02065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ECOK1_RS02070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ECOK1_RS02075	COG0667	Aldo Keto reductase
ECOK1_RS02085	COG0142	geranyltranstransferase activity
ECOK1_RS02100	COG0693	protein deglycase activity
ECOK1_RS02105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECOK1_RS02115	COG2814	Major facilitator Superfamily
ECOK1_RS02125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ECOK1_RS02130	COG1845	cytochrome c oxidase, subunit III
ECOK1_RS02135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECOK1_RS02140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ECOK1_RS02145	COG2223	nitrite transmembrane transporter activity
ECOK1_RS02150	COG3056	Lipoprotein
ECOK1_RS02155	COG0271	Belongs to the BolA IbaG family
ECOK1_RS02180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ECOK1_RS02185	COG0776	regulation of translation
ECOK1_RS02190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECOK1_RS02195	COG1555	photosystem II stabilization
ECOK1_RS02200	COG0824	Thioesterase
ECOK1_RS02210	COG4533	DNA binding
ECOK1_RS02220	COG1522	sequence-specific DNA binding
ECOK1_RS02225	COG1132	(ABC) transporter
ECOK1_RS02230	COG1132	(ABC) transporter
ECOK1_RS02235	COG0347	Belongs to the P(II) protein family
ECOK1_RS02240	COG0004	ammonium transporteR
ECOK1_RS02245	COG1946	Acyl-CoA thioesterase
ECOK1_RS02250	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ECOK1_RS02255	COG3695	enzyme binding
ECOK1_RS02260	COG5507	3-demethylubiquinone-9 3-methyltransferase
ECOK1_RS02265	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECOK1_RS02275	COG0110	maltose O-acetyltransferase activity
ECOK1_RS02290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECOK1_RS02295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS02300	COG1309	transcriptional regulator
ECOK1_RS02305	COG3264	Mechanosensitive ion channel
ECOK1_RS02305	COG1196	nuclear chromosome segregation
ECOK1_RS02320	COG3923	Primosomal replication protein n
ECOK1_RS02325	COG2832	Protein of unknown function (DUF454)
ECOK1_RS02335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECOK1_RS02370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS02375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECOK1_RS02375	COG4651	solute:proton antiporter activity
ECOK1_RS02380	COG2223	nitrite transmembrane transporter activity
ECOK1_RS02385	COG0737	Belongs to the 5'-nucleotidase family
ECOK1_RS02400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECOK1_RS02405	COG3735	TraB family
ECOK1_RS02410	COG3549	Plasmid maintenance system killer
ECOK1_RS02415	COG3093	addiction module antidote protein HigA
ECOK1_RS02420	COG2217	Heavy metal translocating P-type atpase
ECOK1_RS02425	COG2066	Belongs to the glutaminase family
ECOK1_RS02430	COG0531	amino acid
ECOK1_RS02435	COG0789	Transcriptional regulator
ECOK1_RS02460	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECOK1_RS02465	COG0330	HflC and HflK could
ECOK1_RS02470	COG4619	ABC transporter
ECOK1_RS02475	COG0390	transport system, permease component
ECOK1_RS02480	COG3118	belongs to the thioredoxin family
ECOK1_RS02485	COG0300	oxidoreductase activity
ECOK1_RS02490	COG2755	lipolytic protein G-D-S-L family
ECOK1_RS02495	COG4181	ATPase activity
ECOK1_RS02500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ECOK1_RS02525	COG3960	tartronate-semialdehyde synthase activity
ECOK1_RS02530	COG3622	Belongs to the hyi family
ECOK1_RS02535	COG2084	Dehydrogenase
ECOK1_RS02540	COG1953	Uracil, thiamine, allantoin
ECOK1_RS02550	COG2233	PERMEase
ECOK1_RS02555	COG1929	Belongs to the glycerate kinase type-1 family
ECOK1_RS02560	COG3257	ureidoglycine aminohydrolase activity
ECOK1_RS02565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECOK1_RS02570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECOK1_RS02575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECOK1_RS02580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECOK1_RS02585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECOK1_RS02595	COG0549	Belongs to the carbamate kinase family
ECOK1_RS02600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ECOK1_RS02605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ECOK1_RS02620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECOK1_RS02630	COG1988	membrane-bound metal-dependent
ECOK1_RS02635	COG2501	S4 domain
ECOK1_RS02655	COG0582	viral genome integration into host DNA
ECOK1_RS02670	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ECOK1_RS02675	COG5532	Uncharacterized conserved protein (DUF2303)
ECOK1_RS02715	COG1846	Transcriptional regulator
ECOK1_RS02730	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECOK1_RS02740	COG1403	HNH endonuclease
ECOK1_RS02745	COG0484	heat shock protein binding
ECOK1_RS02790	COG3772	lysozyme
ECOK1_RS02825	COG4220	transposase activity
ECOK1_RS02845	COG1030	water channel activity
ECOK1_RS02895	COG1196	nuclear chromosome segregation
ECOK1_RS02935	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECOK1_RS02950	COG0500	methyltransferase
ECOK1_RS02965	COG4571	Outer membrane protease
ECOK1_RS02970	COG0582	viral genome integration into host DNA
ECOK1_RS02975	COG0582	viral genome integration into host DNA
ECOK1_RS02980	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECOK1_RS02985	COG0500	methyltransferase
ECOK1_RS02990	COG4571	Outer membrane protease
ECOK1_RS03000	COG4783	chaperone-mediated protein folding
ECOK1_RS03005	COG1215	transferase activity, transferring glycosyl groups
ECOK1_RS03010	COG5002	protein histidine kinase activity
ECOK1_RS03015	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS03020	COG1538	Outer membrane efflux protein
ECOK1_RS03025	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS03030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS03035	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECOK1_RS03040	COG1113	amino acid transport
ECOK1_RS03045	COG0668	transmembrane transport
ECOK1_RS03050	COG0778	Nitroreductase
ECOK1_RS03055	COG2315	Protein conserved in bacteria
ECOK1_RS03085	COG2977	Belongs to the P-Pant transferase superfamily
ECOK1_RS03095	COG4771	TonB-dependent receptor
ECOK1_RS03100	COG2382	esterase
ECOK1_RS03105	COG3251	PFAM MbtH domain protein
ECOK1_RS03110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ECOK1_RS03110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ECOK1_RS03115	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECOK1_RS03120	COG1120	ATPase activity
ECOK1_RS03125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS03140	COG4592	Periplasmic binding protein
ECOK1_RS03145	COG1169	isochorismate synthase
ECOK1_RS03150	COG1021	2,3-dihydroxybenzoate-AMP ligase
ECOK1_RS03155	COG3433	isochorismatase activity
ECOK1_RS03155	COG1535	isochorismatase
ECOK1_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS03165	COG2050	protein possibly involved in aromatic compounds catabolism
ECOK1_RS03170	COG1966	Carbon starvation protein
ECOK1_RS03175	COG2879	small protein
ECOK1_RS03180	COG0371	Dehydrogenase
ECOK1_RS03185	COG0436	Aminotransferase
ECOK1_RS03190	COG1475	DNA binding
ECOK1_RS03195	COG3969	phosphoadenosine phosphosulfate
ECOK1_RS03200	COG0583	DNA-binding transcription factor activity
ECOK1_RS03205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECOK1_RS03210	COG0450	alkyl hydroperoxide reductase
ECOK1_RS03215	COG3634	alkyl hydroperoxide reductase activity
ECOK1_RS03220	COG0589	response to stress
ECOK1_RS03225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECOK1_RS03230	COG3719	Belongs to the RNase T2 family
ECOK1_RS03235	COG0471	metal ion transport
ECOK1_RS03250	COG3051	citrate lyase alpha subunit
ECOK1_RS03255	COG2301	Belongs to the HpcH HpaI aldolase family
ECOK1_RS03265	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ECOK1_RS03270	COG3290	protein histidine kinase activity
ECOK1_RS03275	COG4565	transcriptional regulatory protein
ECOK1_RS03280	COG3069	C4-dicarboxylate transmembrane transporter activity
ECOK1_RS03300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECOK1_RS03305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECOK1_RS03330	COG1686	Belongs to the peptidase S11 family
ECOK1_RS03335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECOK1_RS03340	COG0772	Belongs to the SEDS family
ECOK1_RS03345	COG0768	penicillin binding
ECOK1_RS03355	COG0799	negative regulation of ribosome biogenesis
ECOK1_RS03360	COG0406	alpha-ribazole phosphatase activity
ECOK1_RS03370	COG1466	dna polymerase III delta subunit
ECOK1_RS03385	COG2888	peptidyl-tyrosine sulfation
ECOK1_RS03395	COG1126	abc transporter atp-binding protein
ECOK1_RS03400	COG0765	amino acid transport
ECOK1_RS03405	COG0765	amino acid transport
ECOK1_RS03410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS03420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ECOK1_RS03425	COG4535	Mg2 and Co2 transporter CorC
ECOK1_RS03435	COG1702	phosphate starvation-inducible protein PhoH
ECOK1_RS03445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECOK1_RS03485	COG0367	asparagine synthase
ECOK1_RS03490	COG0647	UMP catabolic process
ECOK1_RS03495	COG1940	carbohydrate kinase activity
ECOK1_RS03495	COG1846	Transcriptional regulator
ECOK1_RS03500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECOK1_RS03510	COG1263	PTS System
ECOK1_RS03510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS03510	COG2190	(PTS) system
ECOK1_RS03535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECOK1_RS03540	COG1454	alcohol dehydrogenase
ECOK1_RS03545	COG3395	kinase activity
ECOK1_RS03550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ECOK1_RS03555	COG1349	DNA-binding transcription factor activity
ECOK1_RS03580	COG0735	belongs to the Fur family
ECOK1_RS03595	COG0716	FMN binding
ECOK1_RS03605	COG0596	Alpha beta hydrolase
ECOK1_RS03610	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ECOK1_RS03615	COG0033	Phosphoglucomutase
ECOK1_RS03620	COG0531	amino acid
ECOK1_RS03625	COG1982	Orn Lys Arg decarboxylase major
ECOK1_RS03635	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS03640	COG2205	protein histidine kinase activity
ECOK1_RS03670	COG3272	Protein of unknown function (DUF1722)
ECOK1_RS03675	COG0415	Belongs to the DNA photolyase family
ECOK1_RS03685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ECOK1_RS03690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ECOK1_RS03695	COG1984	allophanate hydrolase subunit 2
ECOK1_RS03710	COG3180	Ammonia monooxygenase
ECOK1_RS03715	COG3539	Fimbrial protein
ECOK1_RS03720	COG0372	Belongs to the citrate synthase family
ECOK1_RS03730	COG2009	succinate dehydrogenase
ECOK1_RS03735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ECOK1_RS03740	COG1053	succinate dehydrogenase
ECOK1_RS03745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECOK1_RS03755	COG0567	Dehydrogenase, E1 component
ECOK1_RS03760	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECOK1_RS03770	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECOK1_RS03785	COG1271	oxidase subunit
ECOK1_RS03790	COG1294	oxidase, subunit
ECOK1_RS03795	COG4890	Cyd operon protein YbgT
ECOK1_RS03800	COG3790	cyd operon protein YbgE
ECOK1_RS03805	COG0824	Thioesterase
ECOK1_RS03810	COG0811	peptide transport
ECOK1_RS03815	COG0848	biopolymer transport protein
ECOK1_RS03820	COG3064	Membrane
ECOK1_RS03830	COG2885	chlorophyll binding
ECOK1_RS03835	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ECOK1_RS03880	COG3201	nicotinamide mononucleotide transporter
ECOK1_RS03885	COG1230	cation diffusion facilitator family transporter
ECOK1_RS03900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECOK1_RS03910	COG2017	converts alpha-aldose to the beta-anomer
ECOK1_RS03920	COG1085	galactose-1-phosphate uridylyltransferase
ECOK1_RS03925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ECOK1_RS03930	COG1119	ATPase activity
ECOK1_RS03940	COG2005	Transcriptional regulator
ECOK1_RS03940	COG3585	molybdate ion transport
ECOK1_RS03950	COG0725	ABC transporter, periplasmic molybdate-binding protein
ECOK1_RS03955	COG4149	molybdate abc transporter
ECOK1_RS03965	COG0561	phosphatase activity
ECOK1_RS03975	COG0583	DNA-binding transcription factor activity
ECOK1_RS03980	COG2828	Protein conserved in bacteria
ECOK1_RS03985	COG0471	metal ion transport
ECOK1_RS03990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECOK1_RS03995	COG4677	pectinesterase activity
ECOK1_RS04000	COG1881	PFAM PEBP family protein
ECOK1_RS04005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ECOK1_RS04020	COG2226	methyltransferase
ECOK1_RS04025	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECOK1_RS04035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ECOK1_RS04050	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECOK1_RS04060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ECOK1_RS04065	COG0314	molybdopterin synthase activity
ECOK1_RS04070	COG0670	Belongs to the BI1 family
ECOK1_RS04075	COG0670	Belongs to the BI1 family
ECOK1_RS04080	COG0392	lysyltransferase activity
ECOK1_RS04085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECOK1_RS04090	COG3568	Endonuclease Exonuclease Phosphatase
ECOK1_RS04100	COG0842	Transport permease protein
ECOK1_RS04105	COG0842	Transport permease protein
ECOK1_RS04110	COG1131	(ABC) transporter
ECOK1_RS04120	COG1309	transcriptional regulator
ECOK1_RS04125	COG0513	Belongs to the DEAD box helicase family
ECOK1_RS04135	COG1199	ATP-dependent helicase activity
ECOK1_RS04140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECOK1_RS04145	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECOK1_RS04155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECOK1_RS04180	COG0668	transmembrane transport
ECOK1_RS04185	COG1126	abc transporter atp-binding protein
ECOK1_RS04190	COG0765	amino acid transport
ECOK1_RS04195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS04210	COG5006	permease, DMT superfamily
ECOK1_RS04215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECOK1_RS04220	COG2194	sulfuric ester hydrolase activity
ECOK1_RS04230	COG1321	iron dependent repressor
ECOK1_RS04235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECOK1_RS04240	COG1376	ErfK ybiS ycfS ynhG family protein
ECOK1_RS04245	COG0488	(ABC) transporter
ECOK1_RS04250	COG0561	phosphatase activity
ECOK1_RS04255	COG1882	Formate acetyltransferase
ECOK1_RS04260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECOK1_RS04265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECOK1_RS04270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECOK1_RS04275	COG0303	'Molybdopterin
ECOK1_RS04280	COG1446	asparaginase
ECOK1_RS04305	COG2200	EAL domain
ECOK1_RS04310	COG2199	diguanylate cyclase activity
ECOK1_RS04325	COG2133	pyrroloquinoline quinone binding
ECOK1_RS04330	COG0625	glutathione transferase activity
ECOK1_RS04335	COG1686	Belongs to the peptidase S11 family
ECOK1_RS04340	COG1349	DNA-binding transcription factor activity
ECOK1_RS04345	COG0671	phosphoesterase, PA-phosphatase related
ECOK1_RS04350	COG2814	Major facilitator Superfamily
ECOK1_RS04360	COG0561	phosphatase activity
ECOK1_RS04365	COG0738	Major facilitator superfamily
ECOK1_RS04370	COG3226	Transcriptional regulator
ECOK1_RS04385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECOK1_RS04395	COG0778	Nitroreductase
ECOK1_RS04415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECOK1_RS04420	COG3842	ATPase activity
ECOK1_RS04425	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECOK1_RS04430	COG1177	transmembrane transport
ECOK1_RS04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS04450	COG4160	amino acid transport
ECOK1_RS04455	COG4215	(ABC) transporter
ECOK1_RS04460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS04465	COG1126	abc transporter atp-binding protein
ECOK1_RS04480	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECOK1_RS04485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECOK1_RS04490	COG0702	epimerase
ECOK1_RS04495	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ECOK1_RS04500	COG0028	Belongs to the TPP enzyme family
ECOK1_RS04505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECOK1_RS04515	COG2431	L-lysine efflux transmembrane transporter activity
ECOK1_RS04530	COG3593	DNA synthesis involved in DNA repair
ECOK1_RS04535	COG2990	Protein conserved in bacteria
ECOK1_RS04540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS04550	COG1278	Cold shock
ECOK1_RS04560	COG3311	Transcriptional regulator
ECOK1_RS04630	COG4220	transposase activity
ECOK1_RS04655	COG1518	maintenance of DNA repeat elements
ECOK1_RS04660	COG1203	CRISPR-associated helicase, Cas3
ECOK1_RS04700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ECOK1_RS04705	COG4988	ABC transporter
ECOK1_RS04710	COG0492	ferredoxin-NADP+ reductase activity
ECOK1_RS04715	COG1522	sequence-specific DNA binding
ECOK1_RS04720	COG1674	ftsk spoiiie
ECOK1_RS04720	COG1178	ABC-type Fe3 transport system permease component
ECOK1_RS04730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ECOK1_RS04740	COG0243	molybdopterin cofactor binding
ECOK1_RS04745	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS04750	COG3302	dmso reductase anchor subunit
ECOK1_RS04755	COG1335	isochorismatase
ECOK1_RS04765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECOK1_RS04770	COG4974	Belongs to the 'phage' integrase family
ECOK1_RS04850	COG4695	Portal protein
ECOK1_RS04940	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECOK1_RS04990	COG1882	Formate acetyltransferase
ECOK1_RS04995	COG2116	formate transmembrane transporter activity
ECOK1_RS05000	COG1944	ATP diphosphatase activity
ECOK1_RS05005	COG2323	membrane
ECOK1_RS05020	COG0501	Belongs to the peptidase M48B family
ECOK1_RS05030	COG0539	negative regulation of cytoplasmic translation
ECOK1_RS05040	COG2333	competence protein COMEC
ECOK1_RS05040	COG0658	competence protein
ECOK1_RS05055	COG3214	Protein conserved in bacteria
ECOK1_RS05070	COG3173	Aminoglycoside phosphotransferase
ECOK1_RS05075	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECOK1_RS05080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECOK1_RS05090	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ECOK1_RS05100	COG2989	Protein conserved in bacteria
ECOK1_RS05105	COG3108	Peptidase M15
ECOK1_RS05110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECOK1_RS05115	COG1448	Aminotransferase
ECOK1_RS05140	COG0308	aminopeptidase N
ECOK1_RS05150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECOK1_RS05160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECOK1_RS05165	COG0431	NADPH-dependent FMN reductase
ECOK1_RS05180	COG3217	Mosc domain protein beta barrel domain protein
ECOK1_RS05180	COG0633	Ferredoxin
ECOK1_RS05190	COG0488	(ABC) transporter
ECOK1_RS05195	COG2995	paraquat-inducible protein a
ECOK1_RS05200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECOK1_RS05200	COG3008	intermembrane lipid transfer
ECOK1_RS05205	COG3009	Protein conserved in bacteria
ECOK1_RS05210	COG3130	regulation of translation
ECOK1_RS05220	COG1067	ATP-dependent peptidase activity
ECOK1_RS05230	COG2885	chlorophyll binding
ECOK1_RS05230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECOK1_RS05245	COG3070	regulator of competence-specific genes
ECOK1_RS05250	COG1289	transmembrane transporter activity
ECOK1_RS05255	COG3304	Inner membrane component domain
ECOK1_RS05260	COG0210	DNA helicase
ECOK1_RS05280	COG1832	CoA-binding protein
ECOK1_RS05300	COG2920	part of a sulfur-relay system
ECOK1_RS05305	COG0670	Belongs to the BI1 family
ECOK1_RS05315	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECOK1_RS05320	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECOK1_RS05325	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ECOK1_RS05330	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECOK1_RS05335	COG1999	signal sequence binding
ECOK1_RS05340	COG1773	rubredoxin
ECOK1_RS05345	COG1271	oxidase subunit
ECOK1_RS05350	COG1294	oxidase, subunit
ECOK1_RS05365	COG1278	Cold shock
ECOK1_RS05370	COG1278	Cold shock
ECOK1_RS05385	COG0348	domain, Protein
ECOK1_RS05390	COG2198	Histidine kinase
ECOK1_RS05390	COG0784	Response regulator, receiver
ECOK1_RS05390	COG2205	protein histidine kinase activity
ECOK1_RS05395	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS05400	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS05405	COG3005	denitrification pathway
ECOK1_RS05410	COG0243	molybdopterin cofactor binding
ECOK1_RS05450	COG3729	General stress protein
ECOK1_RS05490	COG1309	transcriptional regulator
ECOK1_RS05495	COG0506	proline dehydrogenase activity
ECOK1_RS05495	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECOK1_RS05495	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECOK1_RS05505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECOK1_RS05525	COG1702	phosphate starvation-inducible protein PhoH
ECOK1_RS05530	COG3658	cytochrome
ECOK1_RS05535	COG1215	transferase activity, transferring glycosyl groups
ECOK1_RS05540	COG1649	PFAM Uncharacterised BCR, COG1649
ECOK1_RS05540	COG0726	polysaccharide deacetylase
ECOK1_RS05545	COG0457	Tetratricopeptide repeat
ECOK1_RS05550	COG3706	GGDEF domain
ECOK1_RS05560	COG0582	viral genome integration into host DNA
ECOK1_RS05585	COG4983	Phage plasmid primase, P4 family domain protein
ECOK1_RS05595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECOK1_RS05605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECOK1_RS05610	COG2222	sugar isomerase
ECOK1_RS05615	COG1349	DNA-binding transcription factor activity
ECOK1_RS05620	COG1349	DNA-binding transcription factor activity
ECOK1_RS05625	COG2721	sulfolactate sulfo-lyase activity
ECOK1_RS05630	COG2721	sulfolactate sulfo-lyase activity
ECOK1_RS05635	COG2721	sulfolactate sulfo-lyase activity
ECOK1_RS05665	COG3539	Fimbrial protein
ECOK1_RS05710	COG2819	hydrolase of the alpha beta superfamily
ECOK1_RS05715	COG2382	esterase
ECOK1_RS05735	COG3385	transposase activity
ECOK1_RS05765	COG4771	TonB-dependent receptor
ECOK1_RS05775	COG0523	cobalamin synthesis protein
ECOK1_RS05780	COG4372	Transposase
ECOK1_RS05815	COG3468	outer membrane autotransporter barrel domain protein
ECOK1_RS05835	COG2003	Belongs to the UPF0758 family
ECOK1_RS05890	COG3381	protein complex oligomerization
ECOK1_RS05900	COG1462	curli production assembly transport component CsgG
ECOK1_RS05915	COG2197	response regulator
ECOK1_RS05945	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECOK1_RS05950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECOK1_RS05975	COG2943	transferase activity, transferring hexosyl groups
ECOK1_RS05980	COG5645	(Lipo)protein
ECOK1_RS06000	COG1560	Kdo2-lipid A biosynthetic process
ECOK1_RS06010	COG2353	YceI-like domain
ECOK1_RS06015	COG3038	cytochrome b561
ECOK1_RS06050	COG2999	glutathione oxidoreductase activity
ECOK1_RS06060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECOK1_RS06070	COG0673	inositol 2-dehydrogenase activity
ECOK1_RS06075	COG0728	peptidoglycan biosynthetic process
ECOK1_RS06080	COG3418	PFAM FlgN family protein
ECOK1_RS06085	COG2747	anti-sigma28 factor FlgM
ECOK1_RS06090	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ECOK1_RS06095	COG1815	bacterial-type flagellum-dependent cell motility
ECOK1_RS06100	COG1558	bacterial-type flagellum-dependent cell motility
ECOK1_RS06105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ECOK1_RS06110	COG1749	Flagellar hook protein flgE
ECOK1_RS06115	COG4787	bacterial-type flagellum-dependent cell motility
ECOK1_RS06120	COG4786	Flagellar basal body rod
ECOK1_RS06135	COG1705	Flagellar rod assembly protein muramidase FlgJ
ECOK1_RS06135	COG3951	Flagellar rod assembly protein muramidase FlgJ
ECOK1_RS06140	COG1256	bacterial-type flagellum assembly
ECOK1_RS06145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECOK1_RS06150	COG1530	ribonuclease E activity
ECOK1_RS06160	COG0564	pseudouridine synthase activity
ECOK1_RS06165	COG0424	maF-like protein
ECOK1_RS06170	COG1399	metal-binding, possibly nucleic acid-binding protein
ECOK1_RS06190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ECOK1_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS06205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECOK1_RS06210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECOK1_RS06215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ECOK1_RS06225	COG0470	DNA polymerase III
ECOK1_RS06230	COG0084	hydrolase, TatD family'
ECOK1_RS06235	COG1263	PTS System
ECOK1_RS06235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS06240	COG4773	Receptor
ECOK1_RS06245	COG0537	adenosine 5'-monophosphoramidase activity
ECOK1_RS06250	COG5633	Lipoprotein
ECOK1_RS06255	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ECOK1_RS06275	COG1252	NADH dehydrogenase
ECOK1_RS06280	COG3134	Outer membrane lipoprotein
ECOK1_RS06285	COG1309	transcriptional regulator
ECOK1_RS06295	COG1388	LysM domain
ECOK1_RS06295	COG1376	ErfK ybiS ycfS ynhG family protein
ECOK1_RS06300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ECOK1_RS06305	COG4763	Acyl-transferase
ECOK1_RS06310	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECOK1_RS06320	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECOK1_RS06330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ECOK1_RS06335	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECOK1_RS06345	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECOK1_RS06350	COG1177	transmembrane transport
ECOK1_RS06375	COG2850	peptidyl-arginine hydroxylation
ECOK1_RS06380	COG2205	protein histidine kinase activity
ECOK1_RS06390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECOK1_RS06410	COG1187	pseudouridine synthase activity
ECOK1_RS06415	COG0538	isocitrate dehydrogenase activity
ECOK1_RS06420	COG0582	viral genome integration into host DNA
ECOK1_RS06610	COG3772	lysozyme
ECOK1_RS06645	COG4220	transposase activity
ECOK1_RS06715	COG1196	nuclear chromosome segregation
ECOK1_RS06745	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECOK1_RS06760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECOK1_RS06765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECOK1_RS06770	COG1121	(ABC) transporter
ECOK1_RS06800	COG5562	phage envelope protein
ECOK1_RS06805	COG0789	Transcriptional regulator
ECOK1_RS06810	COG2200	EAL domain
ECOK1_RS06835	COG2200	EAL domain
ECOK1_RS06890	COG2894	cell division
ECOK1_RS06915	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECOK1_RS06930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECOK1_RS06935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ECOK1_RS06955	COG2719	SpoVR family
ECOK1_RS06965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECOK1_RS06975	COG1619	proteins homologs of microcin C7 resistance protein MccF
ECOK1_RS06985	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ECOK1_RS07000	COG0157	Belongs to the NadC ModD family
ECOK1_RS07005	COG0500	methyltransferase
ECOK1_RS07010	COG1120	ATPase activity
ECOK1_RS07015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS07020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECOK1_RS07030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECOK1_RS07030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS07030	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ECOK1_RS07035	COG1461	Dihydroxyacetone kinase
ECOK1_RS07040	COG2376	Dihydroxyacetone kinase
ECOK1_RS07045	COG3284	Transcriptional regulator
ECOK1_RS07055	COG0012	GTP binding
ECOK1_RS07070	COG0659	secondary active sulfate transmembrane transporter activity
ECOK1_RS07075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ECOK1_RS07100	COG2890	protein-(glutamine-N5) methyltransferase activity
ECOK1_RS07105	COG3094	Invasion gene expression up-regulator, SirB
ECOK1_RS07110	COG2912	Transglutaminase-like superfamily
ECOK1_RS07125	COG0387	Pfam Sodium calcium exchanger
ECOK1_RS07130	COG4572	Cation transport regulator
ECOK1_RS07135	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ECOK1_RS07140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECOK1_RS07145	COG4932	domain protein
ECOK1_RS07150	COG2197	response regulator
ECOK1_RS07155	COG3850	Histidine kinase
ECOK1_RS07165	COG2223	nitrite transmembrane transporter activity
ECOK1_RS07170	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECOK1_RS07175	COG1140	nitrate reductase beta subunit
ECOK1_RS07180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECOK1_RS07185	COG2181	nitrate reductase activity
ECOK1_RS07205	COG0788	formyltetrahydrofolate deformylase activity
ECOK1_RS07215	COG1752	Esterase of the alpha-beta hydrolase superfamily
ECOK1_RS07220	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS07225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ECOK1_RS07235	COG1435	thymidine kinase activity
ECOK1_RS07240	COG3385	transposase activity
ECOK1_RS07245	COG1454	alcohol dehydrogenase
ECOK1_RS07245	COG1012	belongs to the aldehyde dehydrogenase family
ECOK1_RS07250	COG2095	MarC family integral membrane protein
ECOK1_RS07255	COG4166	transmembrane transport
ECOK1_RS07260	COG0601	transmembrane transport
ECOK1_RS07265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECOK1_RS07270	COG0444	Belongs to the ABC transporter superfamily
ECOK1_RS07275	COG4608	Belongs to the ABC transporter superfamily
ECOK1_RS07295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECOK1_RS07300	COG2350	Protein conserved in bacteria
ECOK1_RS07310	COG1607	acyl-coa hydrolase
ECOK1_RS07325	COG3047	cAMP biosynthetic process
ECOK1_RS07330	COG0582	viral genome integration into host DNA
ECOK1_RS07340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECOK1_RS07415	COG1403	HNH endonuclease
ECOK1_RS07420	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECOK1_RS07425	COG0484	heat shock protein binding
ECOK1_RS07475	COG3772	lysozyme
ECOK1_RS07485	COG5562	phage envelope protein
ECOK1_RS07500	COG4220	transposase activity
ECOK1_RS07620	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECOK1_RS07625	COG0500	methyltransferase
ECOK1_RS07640	COG3685	Protein conserved in bacteria
ECOK1_RS07645	COG3685	Protein conserved in bacteria
ECOK1_RS07650	COG3729	General stress protein
ECOK1_RS07665	COG0135	phosphoribosylanthranilate isomerase activity
ECOK1_RS07665	COG0134	indole-3-glycerol-phosphate synthase activity
ECOK1_RS07670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECOK1_RS07670	COG0512	Glutamine amidotransferase of anthranilate synthase
ECOK1_RS07675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECOK1_RS07680	COG0613	PHP domain protein
ECOK1_RS07685	COG0009	L-threonylcarbamoyladenylate synthase
ECOK1_RS07690	COG4907	membrane protein (DUF2207)
ECOK1_RS07695	COG1187	pseudouridine synthase activity
ECOK1_RS07700	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ECOK1_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS07715	COG0616	signal peptide processing
ECOK1_RS07730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECOK1_RS07735	COG0583	DNA-binding transcription factor activity
ECOK1_RS07760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECOK1_RS07770	COG0671	phosphoesterase, PA-phosphatase related
ECOK1_RS07775	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ECOK1_RS07780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ECOK1_RS07790	COG0023	Translation Initiation Factor
ECOK1_RS07800	COG1349	DNA-binding transcription factor activity
ECOK1_RS07810	COG5001	Diguanylate cyclase
ECOK1_RS07825	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECOK1_RS07825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECOK1_RS07830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECOK1_RS07840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS07845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECOK1_RS07855	COG2814	Major facilitator Superfamily
ECOK1_RS07860	COG4172	Belongs to the ABC transporter superfamily
ECOK1_RS07865	COG4172	Belongs to the ABC transporter superfamily
ECOK1_RS07870	COG4171	peptide transport system, permease
ECOK1_RS07875	COG4168	peptide transport system, permease
ECOK1_RS07880	COG4166	transmembrane transport
ECOK1_RS07900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ECOK1_RS07905	COG1842	Phage shock protein A
ECOK1_RS07915	COG1983	PspC domain protein
ECOK1_RS07925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECOK1_RS07930	COG0366	Alpha amylase catalytic
ECOK1_RS07935	COG1653	transport
ECOK1_RS07940	COG1175	transmembrane transport
ECOK1_RS07945	COG0395	ABC-type sugar transport system, permease component
ECOK1_RS07950	COG1063	alcohol dehydrogenase
ECOK1_RS07955	COG1082	Xylose isomerase domain protein TIM barrel
ECOK1_RS07960	COG0673	inositol 2-dehydrogenase activity
ECOK1_RS07965	COG1554	hydrolase, family 65, central catalytic
ECOK1_RS07970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECOK1_RS07985	COG1609	Transcriptional regulator
ECOK1_RS07990	COG3106	COG3106 Predicted ATPase
ECOK1_RS08000	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ECOK1_RS08005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ECOK1_RS08010	COG4948	Mandelate Racemase Muconate Lactonizing
ECOK1_RS08015	COG2866	Carboxypeptidase
ECOK1_RS08020	COG0702	epimerase
ECOK1_RS08025	COG1073	alpha beta
ECOK1_RS08030	COG0583	DNA-binding transcription factor activity
ECOK1_RS08040	COG4166	transmembrane transport
ECOK1_RS08045	COG0668	transmembrane transport
ECOK1_RS08050	COG3182	Iron-regulated membrane protein
ECOK1_RS08055	COG0589	response to stress
ECOK1_RS08060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECOK1_RS08065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECOK1_RS08070	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ECOK1_RS08080	COG2207	Transcriptional regulator
ECOK1_RS08095	COG2840	Smr protein MutS2
ECOK1_RS08100	COG3706	GGDEF domain
ECOK1_RS08115	COG0513	Belongs to the DEAD box helicase family
ECOK1_RS08125	COG0582	viral genome integration into host DNA
ECOK1_RS08135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECOK1_RS08145	COG0589	response to stress
ECOK1_RS08150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECOK1_RS08155	COG1013	pyruvate-flavodoxin oxidoreductase activity
ECOK1_RS08155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ECOK1_RS08155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECOK1_RS08155	COG0674	pyruvate-flavodoxin oxidoreductase activity
ECOK1_RS08160	COG3042	response to heat
ECOK1_RS08165	COG3187	Heat shock protein
ECOK1_RS08170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECOK1_RS08175	COG2911	Protein conserved in bacteria
ECOK1_RS08185	COG3784	Protein of unknown function (DUF1318)
ECOK1_RS08200	COG0667	Aldo Keto reductase
ECOK1_RS08205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECOK1_RS08210	COG4589	Belongs to the CDS family
ECOK1_RS08215	COG2267	carboxylic ester hydrolase activity
ECOK1_RS08220	COG0671	phosphoesterase, PA-phosphatase related
ECOK1_RS08220	COG2453	phosphatase
ECOK1_RS08230	COG1643	Atp-dependent helicase
ECOK1_RS08235	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECOK1_RS08240	COG1012	belongs to the aldehyde dehydrogenase family
ECOK1_RS08245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECOK1_RS08250	COG3038	cytochrome b561
ECOK1_RS08265	COG0840	transmembrane signaling receptor activity
ECOK1_RS08270	COG0583	DNA-binding transcription factor activity
ECOK1_RS08275	COG5383	Protein conserved in bacteria
ECOK1_RS08290	COG2841	Protein conserved in bacteria
ECOK1_RS08295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECOK1_RS08300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECOK1_RS08305	COG1275	C4-dicarboxylate transporter malic acid transport protein
ECOK1_RS08310	COG0500	methyltransferase
ECOK1_RS08320	COG3135	benzoate transporter
ECOK1_RS08325	COG1396	sequence-specific DNA binding
ECOK1_RS08330	COG0826	peptidase U32
ECOK1_RS08340	COG1598	PFAM Uncharacterised protein family UPF0150
ECOK1_RS08345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECOK1_RS08350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECOK1_RS08355	COG3842	ATPase activity
ECOK1_RS08360	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECOK1_RS08365	COG1177	transmembrane transport
ECOK1_RS08390	COG3238	Protein conserved in bacteria
ECOK1_RS08395	COG1247	-acetyltransferase
ECOK1_RS08400	COG1802	Transcriptional regulator
ECOK1_RS08405	COG4772	TonB-dependent receptor
ECOK1_RS08415	COG1113	amino acid transport
ECOK1_RS08420	COG0625	glutathione transferase activity
ECOK1_RS08425	COG0625	glutathione transferase activity
ECOK1_RS08435	COG3501	Rhs element vgr protein
ECOK1_RS08450	COG5433	transposase activity
ECOK1_RS08465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECOK1_RS08470	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ECOK1_RS08475	COG0384	phenazine biosynthesis protein PhzF
ECOK1_RS08480	COG2181	nitrate reductase activity
ECOK1_RS08485	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECOK1_RS08490	COG1140	nitrate reductase beta subunit
ECOK1_RS08495	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECOK1_RS08500	COG2223	nitrite transmembrane transporter activity
ECOK1_RS08505	COG0697	spore germination
ECOK1_RS08510	COG3383	formate dehydrogenase (NAD+) activity
ECOK1_RS08510	COG0243	molybdopterin cofactor binding
ECOK1_RS08515	COG0243	molybdopterin cofactor binding
ECOK1_RS08515	COG3383	formate dehydrogenase (NAD+) activity
ECOK1_RS08520	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS08525	COG2864	formate dehydrogenase
ECOK1_RS08530	COG3093	addiction module antidote protein HigA
ECOK1_RS08540	COG1064	alcohol dehydrogenase
ECOK1_RS08560	COG1764	response to oxidative stress
ECOK1_RS08565	COG2199	diguanylate cyclase activity
ECOK1_RS08565	COG2200	EAL domain
ECOK1_RS08565	COG2202	Pas domain
ECOK1_RS08570	COG3706	GGDEF domain
ECOK1_RS08570	COG3706	GGDEF domain
ECOK1_RS08575	COG1649	PFAM Uncharacterised BCR, COG1649
ECOK1_RS08580	COG0531	amino acid
ECOK1_RS08585	COG0076	glutamate decarboxylase activity
ECOK1_RS08595	COG0612	Peptidase, M16
ECOK1_RS08600	COG4771	TonB-dependent receptor
ECOK1_RS08605	COG4178	(ABC) transporter
ECOK1_RS08610	COG0641	radical SAM
ECOK1_RS08615	COG3119	arylsulfatase activity
ECOK1_RS08620	COG2207	Transcriptional regulator
ECOK1_RS08630	COG0243	molybdopterin cofactor binding
ECOK1_RS08635	COG3539	Fimbrial protein
ECOK1_RS08640	COG3539	Fimbrial protein
ECOK1_RS08645	COG3539	Fimbrial protein
ECOK1_RS08650	COG3188	usher protein
ECOK1_RS08660	COG3539	Fimbrial protein
ECOK1_RS08670	COG0702	epimerase
ECOK1_RS08680	COG3550	peptidyl-serine autophosphorylation
ECOK1_RS08685	COG1396	sequence-specific DNA binding
ECOK1_RS08695	COG3781	membrane
ECOK1_RS08710	COG2199	diguanylate cyclase activity
ECOK1_RS08720	COG2066	Belongs to the glutaminase family
ECOK1_RS08725	COG1012	belongs to the aldehyde dehydrogenase family
ECOK1_RS08730	COG0583	DNA-binding transcription factor activity
ECOK1_RS08745	COG1846	Transcriptional regulator
ECOK1_RS08750	COG4977	sequence-specific DNA binding
ECOK1_RS08760	COG2723	6-phospho-beta-galactosidase activity
ECOK1_RS08770	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECOK1_RS08775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECOK1_RS08785	COG2188	Transcriptional regulator
ECOK1_RS08790	COG0697	spore germination
ECOK1_RS08795	COG2814	Major facilitator Superfamily
ECOK1_RS08805	COG3706	GGDEF domain
ECOK1_RS08810	COG3111	PFAM Bacterial OB fold (BOF) protein
ECOK1_RS08820	COG4221	oxidoreductase activity
ECOK1_RS08825	COG1802	Transcriptional regulator
ECOK1_RS08835	COG0246	Mannitol dehydrogenase
ECOK1_RS08840	COG0477	Major facilitator Superfamily
ECOK1_RS08845	COG1063	alcohol dehydrogenase
ECOK1_RS08850	COG4948	Mandelate Racemase Muconate Lactonizing
ECOK1_RS08865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECOK1_RS08885	COG0243	molybdopterin cofactor binding
ECOK1_RS08890	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS08895	COG3302	dmso reductase anchor subunit
ECOK1_RS08900	COG3381	protein complex oligomerization
ECOK1_RS08910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECOK1_RS08915	COG1940	carbohydrate kinase activity
ECOK1_RS08920	COG0583	DNA-binding transcription factor activity
ECOK1_RS08925	COG2814	Major facilitator Superfamily
ECOK1_RS08940	COG3591	Belongs to the peptidase S1B family
ECOK1_RS08955	COG0628	permease
ECOK1_RS08960	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ECOK1_RS08965	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ECOK1_RS08975	COG0531	amino acid
ECOK1_RS08985	COG3136	membrane protein required for alginate biosynthesis
ECOK1_RS08990	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS08995	COG2205	protein histidine kinase activity
ECOK1_RS09005	COG0114	fumarate hydratase activity
ECOK1_RS09010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECOK1_RS09010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECOK1_RS09015	COG1482	cell wall glycoprotein biosynthetic process
ECOK1_RS09020	COG5339	Protein conserved in bacteria
ECOK1_RS09035	COG3250	beta-galactosidase activity
ECOK1_RS09040	COG1309	transcriptional regulator
ECOK1_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS09050	COG1609	Transcriptional regulator
ECOK1_RS09055	COG1263	PTS System
ECOK1_RS09055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS09060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECOK1_RS09070	COG0673	inositol 2-dehydrogenase activity
ECOK1_RS09110	COG4659	FMN binding
ECOK1_RS09120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECOK1_RS09130	COG3104	oligopeptide transport
ECOK1_RS09135	COG0625	glutathione transferase activity
ECOK1_RS09155	COG3895	Periplasmic Protein
ECOK1_RS09165	COG3133	Outer membrane lipoprotein
ECOK1_RS09180	COG1566	PFAM secretion protein HlyD family protein
ECOK1_RS09185	COG1289	transmembrane transporter activity
ECOK1_RS09190	COG2032	superoxide dismutase activity
ECOK1_RS09195	COG4989	oxidoreductase activity
ECOK1_RS09200	COG3313	Fe-S protein
ECOK1_RS09205	COG1309	transcriptional regulator
ECOK1_RS09210	COG1902	pentaerythritol trinitrate reductase activity
ECOK1_RS09215	COG0346	lactoylglutathione lyase activity
ECOK1_RS09225	COG1201	RNA secondary structure unwinding
ECOK1_RS09230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ECOK1_RS09235	COG0791	NLP P60 protein
ECOK1_RS09240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECOK1_RS09245	COG2814	Major facilitator Superfamily
ECOK1_RS09260	COG0583	DNA-binding transcription factor activity
ECOK1_RS09265	COG2814	Major facilitator Superfamily
ECOK1_RS09270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECOK1_RS09275	COG0307	riboflavin synthase, alpha
ECOK1_RS09285	COG3468	outer membrane autotransporter barrel domain protein
ECOK1_RS09305	COG4529	Protein conserved in bacteria
ECOK1_RS09315	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ECOK1_RS09320	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS09330	COG2414	aldehyde ferredoxin oxidoreductase
ECOK1_RS09340	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS09350	COG0469	pyruvate kinase activity
ECOK1_RS09355	COG4238	major outer membrane lipoprotein
ECOK1_RS09360	COG1376	ErfK ybiS ycfS ynhG family protein
ECOK1_RS09375	COG0719	Fe-S assembly protein
ECOK1_RS09380	COG0396	ATPase activity
ECOK1_RS09385	COG0719	Fe-S assembly protein
ECOK1_RS09390	COG0316	Belongs to the HesB IscA family
ECOK1_RS09400	COG2050	protein possibly involved in aromatic compounds catabolism
ECOK1_RS09405	COG0277	FAD linked oxidase domain protein
ECOK1_RS09405	COG0247	lactate metabolic process
ECOK1_RS09410	COG0628	permease
ECOK1_RS09420	COG0738	Major facilitator superfamily
ECOK1_RS09425	COG2271	Major facilitator Superfamily
ECOK1_RS09440	COG4670	ketone body catabolic process
ECOK1_RS09445	COG1960	acyl-CoA dehydrogenase activity
ECOK1_RS09450	COG2207	Transcriptional regulator
ECOK1_RS09450	COG1917	Cupin 2, conserved barrel domain protein
ECOK1_RS09460	COG2086	electron transfer activity
ECOK1_RS09465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ECOK1_RS09470	COG0644	oxidoreductase
ECOK1_RS09475	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECOK1_RS09480	COG0318	PFAM AMP-dependent synthetase and ligase
ECOK1_RS09485	COG0574	Belongs to the PEP-utilizing enzyme family
ECOK1_RS09485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECOK1_RS09500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECOK1_RS09505	COG4256	Hemin uptake protein
ECOK1_RS09515	COG2200	EAL domain
ECOK1_RS09520	COG0791	NLP P60 protein
ECOK1_RS09530	COG0386	Belongs to the glutathione peroxidase family
ECOK1_RS09595	COG3137	Salt-induced outer membrane protein
ECOK1_RS09600	COG1105	Belongs to the carbohydrate kinase PfkB family
ECOK1_RS09610	COG3001	Fructosamine kinase
ECOK1_RS09620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECOK1_RS09625	COG1988	membrane-bound metal-dependent
ECOK1_RS09630	COG1823	symporter activity
ECOK1_RS09640	COG0753	catalase activity
ECOK1_RS09650	COG1486	melibiose metabolic process
ECOK1_RS09655	COG2169	Transcriptional regulator
ECOK1_RS09655	COG1917	Cupin 2, conserved barrel domain protein
ECOK1_RS09660	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECOK1_RS09665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECOK1_RS09670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECOK1_RS09675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECOK1_RS09690	COG0322	excinuclease ABC activity
ECOK1_RS09700	COG3678	ATP-independent chaperone mediated protein folding
ECOK1_RS09730	COG0708	Exodeoxyribonuclease III
ECOK1_RS09735	COG0398	Pfam SNARE associated Golgi protein
ECOK1_RS09745	COG0398	Pfam SNARE associated Golgi protein
ECOK1_RS09750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECOK1_RS09755	COG4134	Bacterial extracellular solute-binding protein
ECOK1_RS09760	COG4135	transport system, permease component
ECOK1_RS09765	COG4136	ATPase activity
ECOK1_RS09770	COG2897	thiosulfate sulfurtransferase activity
ECOK1_RS09775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECOK1_RS09780	COG0494	nUDIX hydrolase
ECOK1_RS09790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ECOK1_RS09795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECOK1_RS09810	COG0778	Nitroreductase
ECOK1_RS09820	COG0616	signal peptide processing
ECOK1_RS09825	COG0252	asparaginase activity
ECOK1_RS09830	COG1335	isochorismatase
ECOK1_RS09835	COG2814	Major facilitator Superfamily
ECOK1_RS09840	COG1349	DNA-binding transcription factor activity
ECOK1_RS09845	COG0667	Aldo Keto reductase
ECOK1_RS09850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS09855	COG0191	fructose-bisphosphate aldolase activity
ECOK1_RS09860	COG1063	alcohol dehydrogenase
ECOK1_RS09865	COG2271	Major facilitator Superfamily
ECOK1_RS09870	COG1063	alcohol dehydrogenase
ECOK1_RS09875	COG3139	Protein of unknown function (DUF1315)
ECOK1_RS09885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECOK1_RS09890	COG0676	glucose-6-phosphate 1-epimerase activity
ECOK1_RS09895	COG0656	L-ascorbic acid biosynthetic process
ECOK1_RS09900	COG3713	MltA-interacting MipA family protein
ECOK1_RS09905	COG2766	serine protein kinase
ECOK1_RS09915	COG2199	diguanylate cyclase activity
ECOK1_RS09920	COG2199	diguanylate cyclase activity
ECOK1_RS09925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECOK1_RS09940	COG2207	Transcriptional regulator
ECOK1_RS09945	COG2807	transmembrane transport
ECOK1_RS09950	COG3189	MarR family transcriptional regulator
ECOK1_RS09955	COG3042	response to heat
ECOK1_RS09960	COG2203	Gaf domain
ECOK1_RS09960	COG2199	diguanylate cyclase activity
ECOK1_RS09970	COG2261	transglycosylase associated protein
ECOK1_RS09980	COG3615	Tellurite resistance protein tehB
ECOK1_RS09990	COG0583	DNA-binding transcription factor activity
ECOK1_RS09995	COG0473	3-isopropylmalate dehydrogenase activity
ECOK1_RS10000	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ECOK1_RS10005	COG0318	PFAM AMP-dependent synthetase and ligase
ECOK1_RS10010	COG3065	identical protein binding
ECOK1_RS10015	COG1214	PFAM Peptidase M22, glycoprotease
ECOK1_RS10020	COG1199	ATP-dependent helicase activity
ECOK1_RS10025	COG0251	oxidation-reduction process
ECOK1_RS10045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECOK1_RS10055	COG1760	l-serine dehydratase
ECOK1_RS10060	COG2200	EAL domain
ECOK1_RS10065	COG1253	flavin adenine dinucleotide binding
ECOK1_RS10075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS10075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS10080	COG3715	PTS system
ECOK1_RS10085	COG3716	PTS system mannose fructose sorbose family IID component
ECOK1_RS10105	COG2226	methyltransferase
ECOK1_RS10140	COG1414	Transcriptional regulator
ECOK1_RS10145	COG2814	Major facilitator Superfamily
ECOK1_RS10155	COG0793	Belongs to the peptidase S41A family
ECOK1_RS10165	COG1956	GAF domain-containing protein
ECOK1_RS10170	COG2995	paraquat-inducible protein a
ECOK1_RS10175	COG3008	intermembrane lipid transfer
ECOK1_RS10195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECOK1_RS10210	COG1276	copper resistance
ECOK1_RS10215	COG2372	response to copper ion
ECOK1_RS10225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECOK1_RS10230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECOK1_RS10235	COG1770	oligopeptidase
ECOK1_RS10240	COG2979	Protein of unknown function (DUF533)
ECOK1_RS10255	COG3141	response to X-ray
ECOK1_RS10265	COG0800	Aldolase
ECOK1_RS10270	COG0129	dihydroxy-acid dehydratase activity
ECOK1_RS10275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ECOK1_RS10285	COG1737	Transcriptional regulator
ECOK1_RS10290	COG0469	pyruvate kinase activity
ECOK1_RS10295	COG1560	Kdo2-lipid A biosynthetic process
ECOK1_RS10300	COG0739	heme binding
ECOK1_RS10305	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ECOK1_RS10315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECOK1_RS10340	COG0217	transcriptional regulatory protein
ECOK1_RS10345	COG0494	nUDIX hydrolase
ECOK1_RS10355	COG1335	isochorismatase
ECOK1_RS10360	COG1801	Protein of unknown function DUF72
ECOK1_RS10365	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ECOK1_RS10380	COG0243	molybdopterin cofactor binding
ECOK1_RS10385	COG3005	denitrification pathway
ECOK1_RS10395	COG3102	Protein conserved in bacteria
ECOK1_RS10410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECOK1_RS10415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECOK1_RS10420	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ECOK1_RS10425	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS10435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ECOK1_RS10445	COG0840	transmembrane signaling receptor activity
ECOK1_RS10450	COG0835	chemotaxis
ECOK1_RS10455	COG2198	Histidine kinase
ECOK1_RS10455	COG0643	Histidine kinase
ECOK1_RS10460	COG1360	Flagellar Motor Protein
ECOK1_RS10465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECOK1_RS10480	COG0589	response to stress
ECOK1_RS10490	COG1877	trehalose-phosphatase activity
ECOK1_RS10495	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS10505	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS10510	COG1528	Iron-storage protein
ECOK1_RS10530	COG1528	Iron-storage protein
ECOK1_RS10540	COG0814	amino acid
ECOK1_RS10545	COG3318	Belongs to the UPF0149 family
ECOK1_RS10545	COG3012	SEC-C Motif Domain Protein
ECOK1_RS10575	COG2197	response regulator
ECOK1_RS10590	COG2197	response regulator
ECOK1_RS10595	COG1126	abc transporter atp-binding protein
ECOK1_RS10600	COG0765	amino acid transport
ECOK1_RS10610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS10620	COG1191	sigma factor activity
ECOK1_RS10630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECOK1_RS10635	COG1516	flagellar protein fliS
ECOK1_RS10645	COG0366	Alpha amylase catalytic
ECOK1_RS10655	COG2391	methyltransferase activity
ECOK1_RS10660	COG0425	Belongs to the sulfur carrier protein TusA family
ECOK1_RS10665	COG2135	peptidase activity
ECOK1_RS10675	COG2207	Transcriptional regulator
ECOK1_RS10680	COG1881	PFAM PEBP family protein
ECOK1_RS10685	COG2076	Multidrug Resistance protein
ECOK1_RS10705	COG1766	The M ring may be actively involved in energy transduction
ECOK1_RS10710	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECOK1_RS10715	COG1317	bacterial-type flagellum organization
ECOK1_RS10720	COG1157	protein secretion by the type III secretion system
ECOK1_RS10725	COG2882	bacterial-type flagellum organization
ECOK1_RS10730	COG3144	bacterial-type flagellum assembly
ECOK1_RS10735	COG1580	Controls the rotational direction of flagella during chemotaxis
ECOK1_RS10740	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECOK1_RS10745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECOK1_RS10750	COG3190	flagellar
ECOK1_RS10755	COG1338	Plays a role in the flagellum-specific transport system
ECOK1_RS10760	COG1987	bacterial-type flagellum assembly
ECOK1_RS10765	COG1684	flagellar biosynthetic protein fliR
ECOK1_RS10770	COG2197	response regulator
ECOK1_RS10795	COG2354	Protein conserved in bacteria
ECOK1_RS10800	COG0697	spore germination
ECOK1_RS10805	COG3727	T/G mismatch-specific endonuclease activity
ECOK1_RS10810	COG0270	DNA (cytosine-5-)-methyltransferase activity
ECOK1_RS10815	COG1418	mRNA catabolic process
ECOK1_RS10830	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECOK1_RS10845	COG2205	protein histidine kinase activity
ECOK1_RS10850	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS10855	COG2351	hydroxyisourate hydrolase activity
ECOK1_RS10870	COG3443	Belongs to the bacterial solute-binding protein 9 family
ECOK1_RS10905	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECOK1_RS11020	COG3772	lysozyme
ECOK1_RS11060	COG0484	heat shock protein binding
ECOK1_RS11065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECOK1_RS11070	COG1403	HNH endonuclease
ECOK1_RS11085	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ECOK1_RS11145	COG3646	Phage regulatory protein
ECOK1_RS11155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECOK1_RS11190	COG1169	isochorismate synthase
ECOK1_RS11195	COG2814	Major facilitator Superfamily
ECOK1_RS11200	COG1132	(ABC) transporter
ECOK1_RS11215	COG2226	methyltransferase
ECOK1_RS11215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ECOK1_RS11215	COG3433	isochorismatase activity
ECOK1_RS11235	COG1021	2,3-dihydroxybenzoate-AMP ligase
ECOK1_RS11240	COG4771	TonB-dependent receptor
ECOK1_RS11245	COG2373	Large extracellular alpha-helical protein
ECOK1_RS11245	COG4932	domain protein
ECOK1_RS11245	COG1388	LysM domain
ECOK1_RS11250	COG1388	LysM domain
ECOK1_RS11250	COG1470	cell adhesion involved in biofilm formation
ECOK1_RS11255	COG1470	cell adhesion involved in biofilm formation
ECOK1_RS11255	COG1388	LysM domain
ECOK1_RS11260	COG1388	LysM domain
ECOK1_RS11260	COG1470	cell adhesion involved in biofilm formation
ECOK1_RS11270	COG0477	Major facilitator Superfamily
ECOK1_RS11275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ECOK1_RS11280	COG0217	transcriptional regulatory protein
ECOK1_RS11290	COG0583	DNA-binding transcription factor activity
ECOK1_RS11295	COG0583	DNA-binding transcription factor activity
ECOK1_RS11305	COG0534	Mate efflux family protein
ECOK1_RS11315	COG0582	viral genome integration into host DNA
ECOK1_RS11355	COG0154	amidase activity
ECOK1_RS11385	COG1960	acyl-CoA dehydrogenase activity
ECOK1_RS11390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECOK1_RS11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECOK1_RS11410	COG2197	response regulator
ECOK1_RS11425	COG2801	Transposase and inactivated derivatives
ECOK1_RS11435	COG1376	ErfK ybiS ycfS ynhG family protein
ECOK1_RS11450	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ECOK1_RS11465	COG4771	TonB-dependent receptor
ECOK1_RS11470	COG1475	DNA binding
ECOK1_RS11475	COG3969	phosphoadenosine phosphosulfate
ECOK1_RS11480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ECOK1_RS11485	COG1215	transferase activity, transferring glycosyl groups
ECOK1_RS11510	COG3547	Transposase (IS116 IS110 IS902 family)
ECOK1_RS11535	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ECOK1_RS11540	COG0405	Gamma-glutamyltransferase
ECOK1_RS11590	COG3547	Transposase (IS116 IS110 IS902 family)
ECOK1_RS11635	COG1120	ATPase activity
ECOK1_RS11640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS11695	COG2003	Belongs to the UPF0758 family
ECOK1_RS11735	COG1289	transmembrane transporter activity
ECOK1_RS11750	COG2925	Exonuclease
ECOK1_RS11755	COG0531	amino acid
ECOK1_RS11760	COG0583	DNA-binding transcription factor activity
ECOK1_RS11765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECOK1_RS11770	COG4115	mRNA cleavage
ECOK1_RS11775	COG2161	toxin-antitoxin pair type II binding
ECOK1_RS11785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ECOK1_RS11795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECOK1_RS11795	COG0131	Imidazoleglycerol-phosphate dehydratase
ECOK1_RS11800	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ECOK1_RS11815	COG0140	phosphoribosyl-ATP diphosphatase activity
ECOK1_RS11815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ECOK1_RS11820	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECOK1_RS11825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ECOK1_RS11830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ECOK1_RS11835	COG0438	transferase activity, transferring glycosyl groups
ECOK1_RS11840	COG0438	transferase activity, transferring glycosyl groups
ECOK1_RS11845	COG1216	Glycosyl transferase, family 2
ECOK1_RS11845	COG1442	glycosyl transferase family 8
ECOK1_RS11850	COG1216	Glycosyl transferase, family 2
ECOK1_RS11870	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ECOK1_RS11875	COG1091	dTDP-4-dehydrorhamnose reductase activity
ECOK1_RS11880	COG1088	dTDP-glucose 4,6-dehydratase activity
ECOK1_RS11885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ECOK1_RS11895	COG0438	transferase activity, transferring glycosyl groups
ECOK1_RS11900	COG2327	Polysaccharide pyruvyl transferase
ECOK1_RS11905	COG2244	polysaccharide biosynthetic process
ECOK1_RS11910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ECOK1_RS11915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECOK1_RS11920	COG0662	Cupin 2, conserved barrel domain protein
ECOK1_RS11920	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ECOK1_RS11925	COG0297	glycogen (starch) synthase activity
ECOK1_RS11930	COG1051	belongs to the nudix hydrolase family
ECOK1_RS11935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECOK1_RS11940	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ECOK1_RS11945	COG0110	maltose O-acetyltransferase activity
ECOK1_RS11950	COG1216	Glycosyl transferase, family 2
ECOK1_RS11960	COG0438	transferase activity, transferring glycosyl groups
ECOK1_RS11965	COG1045	serine acetyltransferase
ECOK1_RS11970	COG0463	Glycosyl transferase, family 2
ECOK1_RS11975	COG3206	protein involved in exopolysaccharide biosynthesis
ECOK1_RS11975	COG0489	protein tyrosine kinase activity
ECOK1_RS11980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECOK1_RS11985	COG1596	polysaccharide export
ECOK1_RS11990	COG1253	flavin adenine dinucleotide binding
ECOK1_RS12005	COG2982	Protein involved in outer membrane biogenesis
ECOK1_RS12015	COG0572	uridine kinase
ECOK1_RS12020	COG3447	MASE1 domain protein
ECOK1_RS12020	COG5002	protein histidine kinase activity
ECOK1_RS12020	COG5001	Diguanylate cyclase
ECOK1_RS12025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ECOK1_RS12030	COG0443	Heat shock 70 kDa protein
ECOK1_RS12035	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ECOK1_RS12040	COG0631	protein serine/threonine phosphatase activity
ECOK1_RS12045	COG4245	von Willebrand factor, type A
ECOK1_RS12070	COG2205	protein histidine kinase activity
ECOK1_RS12075	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS12080	COG3422	double-strand break repair
ECOK1_RS12105	COG0826	peptidase U32
ECOK1_RS12130	COG1063	alcohol dehydrogenase
ECOK1_RS12135	COG3775	system Galactitol-specific IIC component
ECOK1_RS12140	COG3414	Phosphotransferase system galactitol-specific IIB component
ECOK1_RS12145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS12160	COG1830	Aldolase
ECOK1_RS12165	COG2211	Major facilitator Superfamily
ECOK1_RS12170	COG1397	ADP-ribosylglycohydrolase
ECOK1_RS12175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS12180	COG2188	Transcriptional regulator
ECOK1_RS12185	COG3757	hydrolase, family 25
ECOK1_RS12190	COG0351	phosphomethylpyrimidine kinase
ECOK1_RS12210	COG5455	response to cobalt ion
ECOK1_RS12215	COG3539	Fimbrial protein
ECOK1_RS12220	COG3188	usher protein
ECOK1_RS12225	COG3121	Chaperone
ECOK1_RS12230	COG3539	Fimbrial protein
ECOK1_RS12245	COG0489	protein tyrosine kinase activity
ECOK1_RS12255	COG3831	ATPase activity
ECOK1_RS12275	COG0714	Associated with various cellular activities
ECOK1_RS12280	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ECOK1_RS12285	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ECOK1_RS12290	COG4715	Zinc finger, swim domain protein
ECOK1_RS12295	COG4808	Protein conserved in bacteria
ECOK1_RS12300	COG4807	Protein conserved in bacteria
ECOK1_RS12305	COG3279	Response regulator of the LytR AlgR family
ECOK1_RS12310	COG3275	phosphorelay sensor kinase activity
ECOK1_RS12315	COG0789	Transcriptional regulator
ECOK1_RS12325	COG1174	glycine betaine transport
ECOK1_RS12330	COG1125	glycine betaine transport
ECOK1_RS12335	COG1174	glycine betaine transport
ECOK1_RS12340	COG1732	Glycine betaine
ECOK1_RS12345	COG1472	Belongs to the glycosyl hydrolase 3 family
ECOK1_RS12350	COG0277	FAD linked oxidase domain protein
ECOK1_RS12355	COG1686	Belongs to the peptidase S11 family
ECOK1_RS12365	COG0586	Pfam SNARE associated Golgi protein
ECOK1_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS12375	COG1538	Outer membrane efflux protein
ECOK1_RS12385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECOK1_RS12395	COG1346	cytolysis
ECOK1_RS12405	COG2949	membrane
ECOK1_RS12415	COG0493	'glutamate synthase
ECOK1_RS12420	COG0167	dihydroorotate dehydrogenase activity
ECOK1_RS12420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ECOK1_RS12425	COG4211	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS12435	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS12440	COG1609	Transcriptional regulator
ECOK1_RS12450	COG2311	Membrane
ECOK1_RS12470	COG4771	TonB-dependent receptor
ECOK1_RS12480	COG0833	amino acid
ECOK1_RS12485	COG0583	DNA-binding transcription factor activity
ECOK1_RS12490	COG2855	membrane
ECOK1_RS12500	COG1522	sequence-specific DNA binding
ECOK1_RS12500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS12510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECOK1_RS12515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECOK1_RS12520	COG2313	pseudouridylate synthase activity
ECOK1_RS12525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS12530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS12530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS12530	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ECOK1_RS12535	COG1105	Belongs to the carbohydrate kinase PfkB family
ECOK1_RS12540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS12540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS12545	COG2814	Major facilitator Superfamily
ECOK1_RS12560	COG0246	Mannitol dehydrogenase
ECOK1_RS12565	COG0523	cobalamin synthesis protein
ECOK1_RS12570	COG0671	phosphoesterase, PA-phosphatase related
ECOK1_RS12575	COG0791	NLP P60 protein
ECOK1_RS12580	COG2200	EAL domain
ECOK1_RS12585	COG4166	transmembrane transport
ECOK1_RS12590	COG4174	ABC transporter (Permease)
ECOK1_RS12595	COG4239	(ABC) transporter, permease
ECOK1_RS12600	COG4172	Belongs to the ABC transporter superfamily
ECOK1_RS12610	COG2814	Major facilitator Superfamily
ECOK1_RS12615	COG1187	pseudouridine synthase activity
ECOK1_RS12620	COG1061	Type III restriction enzyme res subunit
ECOK1_RS12640	COG3083	sulfuric ester hydrolase activity
ECOK1_RS12650	COG3468	outer membrane autotransporter barrel domain protein
ECOK1_RS12655	COG3468	outer membrane autotransporter barrel domain protein
ECOK1_RS12665	COG2197	response regulator
ECOK1_RS12670	COG3088	subunit of a heme lyase
ECOK1_RS12670	COG4235	cytochrome complex assembly
ECOK1_RS12675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECOK1_RS12680	COG1138	Cytochrome C-type biogenesis protein
ECOK1_RS12690	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECOK1_RS12695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECOK1_RS12700	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECOK1_RS12710	COG3005	denitrification pathway
ECOK1_RS12715	COG3043	anaerobic respiration
ECOK1_RS12720	COG0348	domain, Protein
ECOK1_RS12725	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS12735	COG3062	negative regulation of establishment of protein localization
ECOK1_RS12740	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS12740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS12760	COG4615	Cyclic peptide transporter
ECOK1_RS12765	COG3145	DNA-N1-methyladenine dioxygenase activity
ECOK1_RS12770	COG2169	Transcriptional regulator
ECOK1_RS12770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECOK1_RS12775	COG1477	protein flavinylation
ECOK1_RS12780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECOK1_RS12790	COG0642	Histidine kinase
ECOK1_RS12790	COG2198	Histidine kinase
ECOK1_RS12795	COG2197	response regulator
ECOK1_RS12800	COG2205	protein histidine kinase activity
ECOK1_RS12800	COG0784	Response regulator, receiver
ECOK1_RS12805	COG3852	Histidine kinase
ECOK1_RS12810	COG2204	response regulator
ECOK1_RS12815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ECOK1_RS12820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ECOK1_RS12825	COG2031	fatty acid transporter
ECOK1_RS12830	COG0183	Belongs to the thiolase family
ECOK1_RS12835	COG4676	Protein conserved in bacteria
ECOK1_RS12840	COG5445	Predicted secreted protein (DUF2300)
ECOK1_RS12845	COG2373	Large extracellular alpha-helical protein
ECOK1_RS12850	COG3234	Protein of unknown function (DUF1175)
ECOK1_RS12855	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ECOK1_RS12860	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECOK1_RS12870	COG3468	outer membrane autotransporter barrel domain protein
ECOK1_RS12880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECOK1_RS12885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECOK1_RS12890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECOK1_RS12895	COG3642	lipopolysaccharide core region biosynthetic process
ECOK1_RS12900	COG0584	glycerophosphoryl diester phosphodiesterase
ECOK1_RS12905	COG2271	Major facilitator Superfamily
ECOK1_RS12910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECOK1_RS12920	COG0247	lactate metabolic process
ECOK1_RS12925	COG5464	transposase or invertase
ECOK1_RS12940	COG2271	Major facilitator Superfamily
ECOK1_RS12950	COG1414	Transcriptional regulator
ECOK1_RS13015	COG0318	PFAM AMP-dependent synthetase and ligase
ECOK1_RS13025	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ECOK1_RS13040	COG1169	isochorismate synthase
ECOK1_RS13045	COG4575	ribosome binding
ECOK1_RS13050	COG2153	protein acetylation
ECOK1_RS13060	COG2304	oxidoreductase activity
ECOK1_RS13065	COG2234	aminopeptidase activity
ECOK1_RS13080	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECOK1_RS13085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECOK1_RS13095	COG0839	Belongs to the complex I subunit 6 family
ECOK1_RS13110	COG1034	ATP synthesis coupled electron transport
ECOK1_RS13115	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ECOK1_RS13120	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ECOK1_RS13140	COG0583	DNA-binding transcription factor activity
ECOK1_RS13145	COG0436	Aminotransferase
ECOK1_RS13155	COG0490	domain, Protein
ECOK1_RS13155	COG0471	metal ion transport
ECOK1_RS13160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECOK1_RS13180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECOK1_RS13185	COG0280	phosphate acetyltransferase
ECOK1_RS13185	COG0857	belongs to the CobB CobQ family
ECOK1_RS13190	COG1288	antiporter activity
ECOK1_RS13195	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ECOK1_RS13200	COG0622	Phosphoesterase
ECOK1_RS13205	COG0625	glutathione transferase activity
ECOK1_RS13210	COG0625	glutathione transferase activity
ECOK1_RS13215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECOK1_RS13220	COG1090	epimerase
ECOK1_RS13225	COG5464	transposase or invertase
ECOK1_RS13230	COG4598	ABC transporter
ECOK1_RS13235	COG4160	amino acid transport
ECOK1_RS13240	COG4215	(ABC) transporter
ECOK1_RS13245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS13250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS13255	COG0163	prenyltransferase activity
ECOK1_RS13260	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ECOK1_RS13265	COG1286	toxin biosynthetic process
ECOK1_RS13270	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ECOK1_RS13275	COG0285	dihydrofolate synthase activity
ECOK1_RS13285	COG0586	Pfam SNARE associated Golgi protein
ECOK1_RS13295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECOK1_RS13305	COG4974	Belongs to the 'phage' integrase family
ECOK1_RS13390	COG4695	Portal protein
ECOK1_RS13470	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECOK1_RS13485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECOK1_RS13555	COG2814	Major facilitator Superfamily
ECOK1_RS13560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECOK1_RS13575	COG3101	peptidyl-lysine hydroxylation
ECOK1_RS13580	COG0730	response to heat
ECOK1_RS13615	COG3539	Fimbrial protein
ECOK1_RS13620	COG3539	Fimbrial protein
ECOK1_RS13625	COG3539	Fimbrial protein
ECOK1_RS13630	COG3121	Chaperone
ECOK1_RS13635	COG3188	usher protein
ECOK1_RS13640	COG3539	Fimbrial protein
ECOK1_RS13645	COG2062	phosphohistidine phosphatase, SixA
ECOK1_RS13660	COG3691	Protein conserved in bacteria
ECOK1_RS13665	COG2067	long-chain fatty acid transport protein
ECOK1_RS13675	COG2116	formate transmembrane transporter activity
ECOK1_RS13685	COG0582	viral genome integration into host DNA
ECOK1_RS13790	COG1783	phage Terminase large subunit
ECOK1_RS13805	COG3646	Phage regulatory protein
ECOK1_RS14005	COG0583	DNA-binding transcription factor activity
ECOK1_RS14010	COG2610	gluconate transmembrane transporter activity
ECOK1_RS14020	COG0477	Major facilitator Superfamily
ECOK1_RS14025	COG1566	PFAM secretion protein HlyD family protein
ECOK1_RS14030	COG2197	response regulator
ECOK1_RS14035	COG2198	Histidine kinase
ECOK1_RS14035	COG2205	protein histidine kinase activity
ECOK1_RS14035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS14035	COG0784	Response regulator, receiver
ECOK1_RS14040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ECOK1_RS14045	COG0679	Auxin Efflux Carrier
ECOK1_RS14050	COG0028	Belongs to the TPP enzyme family
ECOK1_RS14080	COG1560	Kdo2-lipid A biosynthetic process
ECOK1_RS14085	COG0436	Aminotransferase
ECOK1_RS14090	COG3275	phosphorelay sensor kinase activity
ECOK1_RS14095	COG3279	Response regulator of the LytR AlgR family
ECOK1_RS14100	COG2207	Transcriptional regulator
ECOK1_RS14105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS14105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS14105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECOK1_RS14110	COG1363	Peptidase, m42
ECOK1_RS14115	COG0006	proline dipeptidase activity
ECOK1_RS14120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS14125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS14155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECOK1_RS14160	COG2200	EAL domain
ECOK1_RS14160	COG2199	diguanylate cyclase activity
ECOK1_RS14175	COG3415	Transposase
ECOK1_RS14180	COG3415	Transposase
ECOK1_RS14210	COG0583	DNA-binding transcription factor activity
ECOK1_RS14220	COG2211	Major facilitator Superfamily
ECOK1_RS14225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ECOK1_RS14235	COG0583	DNA-binding transcription factor activity
ECOK1_RS14240	COG0385	Bile acid
ECOK1_RS14245	COG3530	Putative quorum-sensing-regulated virulence factor
ECOK1_RS14265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECOK1_RS14270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS14275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECOK1_RS14280	COG2190	(PTS) system
ECOK1_RS14295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECOK1_RS14300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ECOK1_RS14305	COG4208	sulfate ABC transporter
ECOK1_RS14310	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ECOK1_RS14315	COG4150	thiosulfate binding
ECOK1_RS14320	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS14335	COG2837	iron assimilation
ECOK1_RS14355	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECOK1_RS14365	COG2207	Transcriptional regulator
ECOK1_RS14370	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECOK1_RS14375	COG4816	utilization protein
ECOK1_RS14385	COG4303	Ethanolamine ammonia lyase large subunit
ECOK1_RS14390	COG4819	ethanolamine utilization protein
ECOK1_RS14395	COG3192	ethanolamine utilization protein
ECOK1_RS14400	COG1454	alcohol dehydrogenase
ECOK1_RS14405	COG4820	ethanolamine utilization protein (EutJ)
ECOK1_RS14410	COG1012	belongs to the aldehyde dehydrogenase family
ECOK1_RS14415	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ECOK1_RS14420	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ECOK1_RS14425	COG0280	phosphate acetyltransferase
ECOK1_RS14430	COG4812	Cobalamin adenosyltransferase
ECOK1_RS14435	COG4766	ethanolamine catabolic process
ECOK1_RS14440	COG4917	ethanolamine utilization protein
ECOK1_RS14445	COG4810	utilization protein
ECOK1_RS14450	COG0280	phosphate acetyltransferase
ECOK1_RS14450	COG0281	malic enzyme
ECOK1_RS14455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECOK1_RS14460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECOK1_RS14465	COG5342	invasion associated locus B
ECOK1_RS14475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS14475	COG0493	'glutamate synthase
ECOK1_RS14480	COG3850	Histidine kinase
ECOK1_RS14485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECOK1_RS14495	COG1393	Belongs to the ArsC family
ECOK1_RS14510	COG0400	carboxylic ester hydrolase activity
ECOK1_RS14520	COG2321	neutral zinc metallopeptidase
ECOK1_RS14535	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ECOK1_RS14545	COG2716	regulation of RNA biosynthetic process
ECOK1_RS14550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ECOK1_RS14555	COG0628	permease
ECOK1_RS14560	COG4783	chaperone-mediated protein folding
ECOK1_RS14565	COG1393	Belongs to the ArsC family
ECOK1_RS14575	COG2233	PERMEase
ECOK1_RS14590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ECOK1_RS14595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ECOK1_RS14600	COG0248	Ppx GppA phosphatase
ECOK1_RS14605	COG2200	EAL domain
ECOK1_RS14620	COG3133	Outer membrane lipoprotein
ECOK1_RS14635	COG3179	chitinase
ECOK1_RS14780	COG3728	DNA packaging
ECOK1_RS14780	COG5484	DNA packaging
ECOK1_RS14855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECOK1_RS14895	COG0517	IMP dehydrogenase activity
ECOK1_RS14895	COG0516	GMP reductase activity
ECOK1_RS14920	COG1645	bacterial-type flagellum-dependent swarming motility
ECOK1_RS14935	COG2976	Protein conserved in bacteria
ECOK1_RS14965	COG4953	penicillin-binding protein 1C
ECOK1_RS14970	COG2373	Large extracellular alpha-helical protein
ECOK1_RS14975	COG2897	thiosulfate sulfurtransferase activity
ECOK1_RS14990	COG2975	iron-sulfur cluster assembly
ECOK1_RS14995	COG0633	Ferredoxin
ECOK1_RS15015	COG0822	iron-sulfur transferase activity
ECOK1_RS15035	COG0483	inositol monophosphate 1-phosphatase activity
ECOK1_RS15040	COG1073	alpha beta
ECOK1_RS15045	COG3711	transcriptional antiterminator
ECOK1_RS15050	COG2814	Major facilitator Superfamily
ECOK1_RS15055	COG2259	Doxx family
ECOK1_RS15060	COG2017	converts alpha-aldose to the beta-anomer
ECOK1_RS15065	COG1063	alcohol dehydrogenase
ECOK1_RS15070	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS15075	COG1129	ABC transporter
ECOK1_RS15080	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS15085	COG0457	Tetratricopeptide repeat
ECOK1_RS15090	COG1940	carbohydrate kinase activity
ECOK1_RS15100	COG1017	nitric oxide dioxygenase activity
ECOK1_RS15100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECOK1_RS15105	COG0347	Belongs to the P(II) protein family
ECOK1_RS15110	COG2204	response regulator
ECOK1_RS15115	COG3170	Tfp pilus assembly protein FimV
ECOK1_RS15120	COG2205	protein histidine kinase activity
ECOK1_RS15135	COG0590	tRNA wobble adenosine to inosine editing
ECOK1_RS15140	COG0560	Phosphoserine phosphatase
ECOK1_RS15145	COG1737	Transcriptional regulator
ECOK1_RS15150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS15170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ECOK1_RS15190	COG0681	Belongs to the peptidase S26 family
ECOK1_RS15200	COG3086	response to oxidative stress
ECOK1_RS15205	COG3026	antisigma factor binding
ECOK1_RS15210	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ECOK1_RS15215	COG1595	DNA-templated transcription, initiation
ECOK1_RS15225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECOK1_RS15235	COG0513	Belongs to the DEAD box helicase family
ECOK1_RS15240	COG0583	DNA-binding transcription factor activity
ECOK1_RS15260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECOK1_RS15270	COG3118	belongs to the thioredoxin family
ECOK1_RS15275	COG3148	PFAM DTW domain containing protein
ECOK1_RS15280	COG0045	succinate-CoA ligase (ADP-forming) activity
ECOK1_RS15280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECOK1_RS15280	COG1042	CoA-binding domain protein
ECOK1_RS15285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECOK1_RS15290	COG5544	Lipoprotein
ECOK1_RS15295	COG0477	Major facilitator Superfamily
ECOK1_RS15335	COG0542	response to heat
ECOK1_RS15345	COG0564	pseudouridine synthase activity
ECOK1_RS15350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECOK1_RS15360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECOK1_RS15365	COG0077	Prephenate dehydratase
ECOK1_RS15365	COG1605	Chorismate mutase
ECOK1_RS15370	COG1605	Chorismate mutase
ECOK1_RS15370	COG0287	Prephenate dehydrogenase
ECOK1_RS15375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECOK1_RS15390	COG2199	diguanylate cyclase activity
ECOK1_RS15395	COG2885	chlorophyll binding
ECOK1_RS15420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECOK1_RS15425	COG4137	Cytochrome C assembly protein
ECOK1_RS15430	COG4536	flavin adenine dinucleotide binding
ECOK1_RS15450	COG0497	DNA recombination
ECOK1_RS15455	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECOK1_RS15465	COG2867	negative regulation of translational initiation
ECOK1_RS15505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ECOK1_RS15515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECOK1_RS15530	COG3778	Protein conserved in bacteria
ECOK1_RS15535	COG3299	homolog of phage Mu protein gp47
ECOK1_RS15555	COG4228	DNA circulation
ECOK1_RS15575	COG4386	tail sheath protein
ECOK1_RS15620	COG4695	Portal protein
ECOK1_RS15630	COG4626	Terminase
ECOK1_RS15630	COG1802	Transcriptional regulator
ECOK1_RS15675	COG0484	heat shock protein binding
ECOK1_RS15680	COG1403	HNH endonuclease
ECOK1_RS15690	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECOK1_RS15700	COG4725	Belongs to the MT-A70-like family
ECOK1_RS15710	COG1846	Transcriptional regulator
ECOK1_RS15725	COG4197	protein conserved in bacteria, prophage-related
ECOK1_RS15730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECOK1_RS15745	COG5532	Uncharacterized conserved protein (DUF2303)
ECOK1_RS15750	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ECOK1_RS15755	COG0582	viral genome integration into host DNA
ECOK1_RS15785	COG0579	oxidoreductase
ECOK1_RS15790	COG1012	belongs to the aldehyde dehydrogenase family
ECOK1_RS15795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECOK1_RS15800	COG1113	amino acid transport
ECOK1_RS15805	COG1802	Transcriptional regulator
ECOK1_RS15810	COG1652	LysM domain
ECOK1_RS15815	COG0401	homolog of Blt101
ECOK1_RS15820	COG0640	Transcriptional regulator
ECOK1_RS15825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECOK1_RS15830	COG2916	Histone family protein nucleoid-structuring protein H-NS
ECOK1_RS15845	COG4575	ribosome binding
ECOK1_RS15855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECOK1_RS15860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECOK1_RS15870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECOK1_RS15875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECOK1_RS15880	COG4175	Glycine betaine
ECOK1_RS15885	COG4176	ABC-type proline glycine betaine transport system permease component
ECOK1_RS15890	COG2113	Glycine betaine
ECOK1_RS15895	COG2814	Major facilitator Superfamily
ECOK1_RS15900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ECOK1_RS15910	COG1846	Transcriptional regulator
ECOK1_RS15915	COG1566	PFAM secretion protein HlyD family protein
ECOK1_RS15920	COG2814	Major facilitator Superfamily
ECOK1_RS15945	COG1238	metal cluster binding
ECOK1_RS15950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECOK1_RS15985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ECOK1_RS16010	COG1546	Belongs to the CinA family
ECOK1_RS16015	COG2951	lytic endotransglycosylase activity
ECOK1_RS16020	COG3730	PTS system glucitol sorbitol-specific
ECOK1_RS16025	COG3732	PTS system glucitol sorbitol-specific
ECOK1_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS16040	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS16045	COG1349	DNA-binding transcription factor activity
ECOK1_RS16050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECOK1_RS16050	COG0517	IMP dehydrogenase activity
ECOK1_RS16070	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ECOK1_RS16075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS16080	COG1609	Transcriptional regulator
ECOK1_RS16085	COG1263	PTS System
ECOK1_RS16085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS16090	COG2723	6-phospho-beta-galactosidase activity
ECOK1_RS16095	COG5499	transcription regulator containing HTH domain
ECOK1_RS16100	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECOK1_RS16110	COG3260	NADH ubiquinone oxidoreductase 20
ECOK1_RS16115	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECOK1_RS16120	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECOK1_RS16120	COG3261	NADH dehydrogenase
ECOK1_RS16125	COG0650	Formate hydrogenlyase subunit 4
ECOK1_RS16130	COG0651	ATP synthesis coupled electron transport
ECOK1_RS16135	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS16145	COG0375	protein maturation
ECOK1_RS16150	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ECOK1_RS16155	COG0298	carbon dioxide binding
ECOK1_RS16160	COG0409	Hydrogenase expression formation protein
ECOK1_RS16165	COG0309	Hydrogenase expression formation protein (HypE)
ECOK1_RS16170	COG3604	Transcriptional regulator
ECOK1_RS16190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECOK1_RS16195	COG1349	DNA-binding transcription factor activity
ECOK1_RS16200	COG2084	Dehydrogenase
ECOK1_RS16205	COG3395	kinase activity
ECOK1_RS16210	COG0235	Class ii aldolase
ECOK1_RS16215	COG3622	Belongs to the hyi family
ECOK1_RS16220	COG2610	gluconate transmembrane transporter activity
ECOK1_RS16240	COG4942	peptidase
ECOK1_RS16240	COG1388	LysM domain
ECOK1_RS16295	COG2234	aminopeptidase activity
ECOK1_RS16320	COG0720	synthase
ECOK1_RS16325	COG0644	oxidoreductase
ECOK1_RS16330	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ECOK1_RS16335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ECOK1_RS16340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ECOK1_RS16345	COG2086	electron transfer activity
ECOK1_RS16350	COG0477	Major facilitator Superfamily
ECOK1_RS16355	COG0277	FAD linked oxidase domain protein
ECOK1_RS16360	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS16365	COG2223	nitrite transmembrane transporter activity
ECOK1_RS16370	COG1070	Carbohydrate kinase
ECOK1_RS16380	COG0602	queuosine metabolic process
ECOK1_RS16390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECOK1_RS16400	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ECOK1_RS16415	COG3956	TIGRFAM MazG family protein
ECOK1_RS16420	COG2337	Toxic component of a toxin-antitoxin (TA) module
ECOK1_RS16425	COG2336	PFAM SpoVT AbrB
ECOK1_RS16430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECOK1_RS16440	COG2205	protein histidine kinase activity
ECOK1_RS16440	COG3850	Histidine kinase
ECOK1_RS16440	COG4999	Histidine kinase
ECOK1_RS16440	COG3437	response regulator, receiver
ECOK1_RS16445	COG4948	Mandelate Racemase Muconate Lactonizing
ECOK1_RS16450	COG4948	Mandelate Racemase Muconate Lactonizing
ECOK1_RS16455	COG2271	Major facilitator Superfamily
ECOK1_RS16460	COG0716	FMN binding
ECOK1_RS16465	COG0564	pseudouridine synthase activity
ECOK1_RS16470	COG3098	single-species biofilm formation
ECOK1_RS16490	COG1611	Belongs to the LOG family
ECOK1_RS16495	COG0814	amino acid
ECOK1_RS16500	COG1760	l-serine dehydratase
ECOK1_RS16510	COG1454	alcohol dehydrogenase
ECOK1_RS16515	COG0235	Class ii aldolase
ECOK1_RS16520	COG0738	Major facilitator superfamily
ECOK1_RS16530	COG1070	Carbohydrate kinase
ECOK1_RS16540	COG1349	DNA-binding transcription factor activity
ECOK1_RS16550	COG2363	Small membrane protein
ECOK1_RS16555	COG0583	DNA-binding transcription factor activity
ECOK1_RS16565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECOK1_RS16570	COG2166	iron-sulfur cluster assembly
ECOK1_RS16575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ECOK1_RS16580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ECOK1_RS16620	COG2885	chlorophyll binding
ECOK1_RS16725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECOK1_RS16730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS16730	COG1263	PTS System
ECOK1_RS16735	COG3711	transcriptional antiterminator
ECOK1_RS16740	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECOK1_RS16745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ECOK1_RS16745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ECOK1_RS16750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ECOK1_RS16755	COG1074	ATP-dependent DNA helicase activity
ECOK1_RS16760	COG1025	Belongs to the peptidase M16 family
ECOK1_RS16765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ECOK1_RS16770	COG4967	type IV pilus modification protein PilV
ECOK1_RS16780	COG4795	General secretion pathway protein
ECOK1_RS16785	COG2165	general secretion pathway protein
ECOK1_RS16800	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ECOK1_RS16825	COG0861	Integral membrane protein TerC family
ECOK1_RS16835	COG0667	Aldo Keto reductase
ECOK1_RS16850	COG1609	Transcriptional regulator
ECOK1_RS16860	COG0583	DNA-binding transcription factor activity
ECOK1_RS16865	COG1794	racemase activity, acting on amino acids and derivatives
ECOK1_RS16870	COG2814	Major facilitator Superfamily
ECOK1_RS16875	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS16885	COG0183	Belongs to the thiolase family
ECOK1_RS16890	COG0814	amino acid
ECOK1_RS16900	COG4942	peptidase
ECOK1_RS16905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECOK1_RS16910	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECOK1_RS16915	COG2080	2 iron, 2 sulfur cluster binding
ECOK1_RS16920	COG3829	transcription factor binding
ECOK1_RS16925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECOK1_RS16930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECOK1_RS16935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECOK1_RS16945	COG0549	Belongs to the carbamate kinase family
ECOK1_RS16950	COG3608	succinylglutamate desuccinylase aspartoacylase
ECOK1_RS16950	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ECOK1_RS16955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECOK1_RS16960	COG2068	MobA-Related Protein
ECOK1_RS16965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS16965	COG0493	'glutamate synthase
ECOK1_RS16970	COG0402	S-adenosylhomocysteine deaminase activity
ECOK1_RS16975	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECOK1_RS16980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECOK1_RS16980	COG2080	2 iron, 2 sulfur cluster binding
ECOK1_RS16985	COG2233	PERMEase
ECOK1_RS16990	COG0402	S-adenosylhomocysteine deaminase activity
ECOK1_RS16995	COG2252	PERMEase
ECOK1_RS17000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS17005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS17005	COG0493	'glutamate synthase
ECOK1_RS17015	COG2233	PERMEase
ECOK1_RS17030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECOK1_RS17040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ECOK1_RS17045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECOK1_RS17055	COG0716	FMN binding
ECOK1_RS17065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ECOK1_RS17075	COG1272	protein, Hemolysin III
ECOK1_RS17085	COG2723	6-phospho-beta-galactosidase activity
ECOK1_RS17105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECOK1_RS17110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECOK1_RS17115	COG0006	proline dipeptidase activity
ECOK1_RS17130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ECOK1_RS17135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECOK1_RS17155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECOK1_RS17155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ECOK1_RS17160	COG0583	DNA-binding transcription factor activity
ECOK1_RS17165	COG2968	Membrane
ECOK1_RS17170	COG1279	arginine transmembrane transporter activity
ECOK1_RS17175	COG0668	transmembrane transport
ECOK1_RS17180	COG0191	fructose-bisphosphate aldolase activity
ECOK1_RS17215	COG1122	ATPase activity
ECOK1_RS17220	COG1072	(Pantothenic acid kinase))
ECOK1_RS17230	COG1494	fructose-1,6-bisphosphatase
ECOK1_RS17235	COG1063	alcohol dehydrogenase
ECOK1_RS17240	COG2213	PTS system mannitol-specific
ECOK1_RS17245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS17250	COG0330	HflC and HflK could
ECOK1_RS17255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECOK1_RS17260	COG0501	Belongs to the peptidase M48B family
ECOK1_RS17275	COG1166	arginine decarboxylase activity
ECOK1_RS17300	COG2814	Major facilitator Superfamily
ECOK1_RS17310	COG2356	endonuclease I
ECOK1_RS17315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ECOK1_RS17320	COG0189	ligase activity
ECOK1_RS17335	COG2805	Type II/IV secretion system protein
ECOK1_RS17340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ECOK1_RS17345	COG0762	integral membrane protein
ECOK1_RS17355	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ECOK1_RS17360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECOK1_RS17370	COG0252	asparaginase activity
ECOK1_RS17385	COG3171	Protein conserved in bacteria
ECOK1_RS17395	COG1194	a g-specific adenine glycosylase
ECOK1_RS17410	COG2211	Major facilitator Superfamily
ECOK1_RS17415	COG1982	Orn Lys Arg decarboxylase major
ECOK1_RS17420	COG1811	Na channel or pump
ECOK1_RS17485	COG2089	acid synthase
ECOK1_RS17505	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECOK1_RS17535	COG2165	general secretion pathway protein
ECOK1_RS17540	COG1459	type II secretion system
ECOK1_RS17545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECOK1_RS17555	COG3031	protein transport across the cell outer membrane
ECOK1_RS17570	COG3064	Membrane
ECOK1_RS17580	COG1620	l-lactate permease
ECOK1_RS17585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECOK1_RS17590	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ECOK1_RS17595	COG0247	lactate metabolic process
ECOK1_RS17600	COG0277	FAD linked oxidase domain protein
ECOK1_RS17605	COG0277	FAD linked oxidase domain protein
ECOK1_RS17610	COG2186	Transcriptional regulator
ECOK1_RS17615	COG0456	acetyltransferase
ECOK1_RS17620	COG0318	PFAM AMP-dependent synthetase and ligase
ECOK1_RS17630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECOK1_RS17635	COG0156	8-amino-7-oxononanoate synthase activity
ECOK1_RS17645	COG0795	lipopolysaccharide-transporting ATPase activity
ECOK1_RS17650	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECOK1_RS17660	COG2244	polysaccharide biosynthetic process
ECOK1_RS17665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECOK1_RS17670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECOK1_RS17675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECOK1_RS17680	COG0306	phosphate transporter
ECOK1_RS17685	COG0754	glutathionylspermidine amidase activity
ECOK1_RS17690	COG0625	glutathione transferase activity
ECOK1_RS17695	COG0298	carbon dioxide binding
ECOK1_RS17700	COG0375	protein maturation
ECOK1_RS17705	COG1773	rubredoxin
ECOK1_RS17710	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECOK1_RS17715	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ECOK1_RS17720	COG5557	Pfam Polysulphide reductase, NrfD
ECOK1_RS17725	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS17730	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ECOK1_RS17750	COG0667	Aldo Keto reductase
ECOK1_RS17760	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS17765	COG0848	biopolymer transport protein
ECOK1_RS17770	COG0811	peptide transport
ECOK1_RS17780	COG0626	cystathionine gamma-synthase activity
ECOK1_RS17785	COG0586	Pfam SNARE associated Golgi protein
ECOK1_RS17790	COG2207	Transcriptional regulator
ECOK1_RS17800	COG1979	alcohol dehydrogenase
ECOK1_RS17805	COG0656	L-ascorbic acid biosynthetic process
ECOK1_RS17815	COG4238	major outer membrane lipoprotein
ECOK1_RS17820	COG1032	radical SAM domain protein
ECOK1_RS17825	COG2186	Transcriptional regulator
ECOK1_RS17830	COG0246	Mannitol dehydrogenase
ECOK1_RS17835	COG1063	alcohol dehydrogenase
ECOK1_RS17840	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECOK1_RS17860	COG2132	Multicopper oxidase
ECOK1_RS17865	COG0204	Acyl-transferase
ECOK1_RS17870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECOK1_RS17875	COG4166	transmembrane transport
ECOK1_RS17880	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECOK1_RS17885	COG3111	PFAM Bacterial OB fold (BOF) protein
ECOK1_RS17890	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS17895	COG0642	Histidine kinase
ECOK1_RS17915	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECOK1_RS17920	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ECOK1_RS17925	COG1737	Transcriptional regulator
ECOK1_RS17935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS17940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS17945	COG1120	ATPase activity
ECOK1_RS17950	COG4774	siderophore transport
ECOK1_RS17955	COG0187	DNA topoisomerase II activity
ECOK1_RS17960	COG3150	esterase
ECOK1_RS17965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ECOK1_RS17970	COG3151	Protein conserved in bacteria
ECOK1_RS17975	COG0494	nUDIX hydrolase
ECOK1_RS17980	COG1538	Outer membrane efflux protein
ECOK1_RS17995	COG0754	glutathionylspermidine amidase activity
ECOK1_RS18005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ECOK1_RS18015	COG3384	dioxygenase
ECOK1_RS18030	COG3539	Fimbrial protein
ECOK1_RS18035	COG3188	usher protein
ECOK1_RS18040	COG3121	Chaperone
ECOK1_RS18045	COG3539	Fimbrial protein
ECOK1_RS18065	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECOK1_RS18070	COG2268	Band 7 protein
ECOK1_RS18090	COG3025	triphosphatase activity
ECOK1_RS18100	COG4991	sh3 domain protein
ECOK1_RS18115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECOK1_RS18135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECOK1_RS18150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ECOK1_RS18155	COG0358	DNA primase activity
ECOK1_RS18160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECOK1_RS18175	COG2375	cellular response to nickel ion
ECOK1_RS18180	COG1695	Transcriptional regulator
ECOK1_RS18185	COG0840	transmembrane signaling receptor activity
ECOK1_RS18195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECOK1_RS18200	COG1609	Transcriptional regulator
ECOK1_RS18205	COG3250	beta-galactosidase activity
ECOK1_RS18210	COG2731	YhcH YjgK YiaL family protein
ECOK1_RS18215	COG0531	amino acid
ECOK1_RS18225	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ECOK1_RS18225	COG3408	Glycogen debranching enzyme
ECOK1_RS18230	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECOK1_RS18230	COG1902	pentaerythritol trinitrate reductase activity
ECOK1_RS18240	COG1451	nucleotide metabolic process
ECOK1_RS18245	COG2949	membrane
ECOK1_RS18250	COG0673	inositol 2-dehydrogenase activity
ECOK1_RS18255	COG0861	Integral membrane protein TerC family
ECOK1_RS18270	COG2721	sulfolactate sulfo-lyase activity
ECOK1_RS18280	COG2271	Major facilitator Superfamily
ECOK1_RS18285	COG2186	Transcriptional regulator
ECOK1_RS18290	COG0586	Pfam SNARE associated Golgi protein
ECOK1_RS18300	COG1422	Protein of unknown function (DUF1090)
ECOK1_RS18305	COG4575	ribosome binding
ECOK1_RS18310	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ECOK1_RS18320	COG2259	Doxx family
ECOK1_RS18325	COG0435	Glutathione S-transferase
ECOK1_RS18330	COG3152	Membrane
ECOK1_RS18335	COG0583	DNA-binding transcription factor activity
ECOK1_RS18340	COG1741	Belongs to the pirin family
ECOK1_RS18355	COG0814	amino acid
ECOK1_RS18360	COG1760	l-serine dehydratase
ECOK1_RS18365	COG0251	oxidation-reduction process
ECOK1_RS18370	COG1882	Formate acetyltransferase
ECOK1_RS18375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECOK1_RS18385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECOK1_RS18390	COG0583	DNA-binding transcription factor activity
ECOK1_RS18400	COG1929	Belongs to the glycerate kinase type-1 family
ECOK1_RS18405	COG2084	Dehydrogenase
ECOK1_RS18415	COG2271	Major facilitator Superfamily
ECOK1_RS18420	COG2721	sulfolactate sulfo-lyase activity
ECOK1_RS18425	COG1349	DNA-binding transcription factor activity
ECOK1_RS18435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS18445	COG3716	PTS system mannose fructose sorbose family IID component
ECOK1_RS18450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS18455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECOK1_RS18460	COG2222	sugar isomerase
ECOK1_RS18470	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS18475	COG3715	PTS system
ECOK1_RS18480	COG3716	PTS system mannose fructose sorbose family IID component
ECOK1_RS18485	COG0363	glucosamine-6-phosphate deaminase activity
ECOK1_RS18490	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECOK1_RS18495	COG3107	peptidoglycan biosynthetic process
ECOK1_RS18510	COG2823	Periplasmic or secreted lipoprotein
ECOK1_RS18515	COG0701	Predicted permease
ECOK1_RS18520	COG0702	epimerase
ECOK1_RS18525	COG0693	protein deglycase activity
ECOK1_RS18540	COG3153	acetyltransferase
ECOK1_RS18545	COG3154	lipid carrier protein
ECOK1_RS18550	COG0826	peptidase U32
ECOK1_RS18555	COG0826	peptidase U32
ECOK1_RS18560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECOK1_RS18565	COG0814	amino acid
ECOK1_RS18575	COG0513	Belongs to the DEAD box helicase family
ECOK1_RS18610	COG0195	Participates in both transcription termination and antitermination
ECOK1_RS18630	COG2194	sulfuric ester hydrolase activity
ECOK1_RS18640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECOK1_RS18650	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ECOK1_RS18655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ECOK1_RS18665	COG1534	Rna-binding protein
ECOK1_RS18670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECOK1_RS18675	COG2027	D-alanyl-D-alanine carboxypeptidase
ECOK1_RS18685	COG0697	spore germination
ECOK1_RS18700	COG0142	geranyltranstransferase activity
ECOK1_RS18705	COG3423	Transcriptional regulator
ECOK1_RS18715	COG5007	Belongs to the BolA IbaG family
ECOK1_RS18720	COG3113	response to antibiotic
ECOK1_RS18725	COG2854	intermembrane phospholipid transfer
ECOK1_RS18730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECOK1_RS18735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ECOK1_RS18740	COG1127	ABC transporter
ECOK1_RS18745	COG0530	calcium, potassium:sodium antiporter activity
ECOK1_RS18750	COG0517	IMP dehydrogenase activity
ECOK1_RS18750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECOK1_RS18755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ECOK1_RS18760	COG3117	lipopolysaccharide transmembrane transporter activity
ECOK1_RS18765	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ECOK1_RS18770	COG1137	ATPase activity
ECOK1_RS18775	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ECOK1_RS18780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECOK1_RS18795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS18800	COG0515	serine threonine protein kinase
ECOK1_RS18810	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ECOK1_RS18815	COG0784	Response regulator, receiver
ECOK1_RS18815	COG5002	protein histidine kinase activity
ECOK1_RS18815	COG2198	Histidine kinase
ECOK1_RS18820	COG1242	4 iron, 4 sulfur cluster binding
ECOK1_RS18825	COG0070	glutamate synthase
ECOK1_RS18825	COG0067	glutamate synthase
ECOK1_RS18825	COG0069	glutamate synthase activity
ECOK1_RS18830	COG0493	'glutamate synthase
ECOK1_RS18835	COG2731	YhcH YjgK YiaL family protein
ECOK1_RS18865	COG2969	positive regulation of protein catabolic process
ECOK1_RS18870	COG0625	glutathione transferase activity
ECOK1_RS18885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ECOK1_RS18890	COG3105	Protein conserved in bacteria
ECOK1_RS18895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECOK1_RS18900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECOK1_RS18920	COG2732	(Barnase) inhibitor
ECOK1_RS18940	COG0583	DNA-binding transcription factor activity
ECOK1_RS18945	COG0312	modulator of DNA gyrase
ECOK1_RS18950	COG3164	Protein of unknown function
ECOK1_RS18955	COG1530	ribonuclease E activity
ECOK1_RS18965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ECOK1_RS18970	COG1792	Involved in formation and maintenance of cell shape
ECOK1_RS18975	COG1077	Cell shape determining protein MreB Mrl
ECOK1_RS18985	COG2199	diguanylate cyclase activity
ECOK1_RS18985	COG2200	EAL domain
ECOK1_RS18990	COG0604	alcohol dehydrogenase
ECOK1_RS19010	COG0511	ligase activity, forming carbon-carbon bonds
ECOK1_RS19015	COG0439	Biotin carboxylase
ECOK1_RS19025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS19030	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS19035	COG1129	ABC transporter
ECOK1_RS19040	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS19050	COG1349	DNA-binding transcription factor activity
ECOK1_RS19055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS19060	COG3924	membrane
ECOK1_RS19065	COG4145	pantothenate transmembrane transporter activity
ECOK1_RS19075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECOK1_RS19085	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ECOK1_RS19095	COG1309	transcriptional regulator
ECOK1_RS19100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS19105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECOK1_RS19125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECOK1_RS19130	COG4597	amino acid ABC transporter
ECOK1_RS19135	COG0765	amino acid transport
ECOK1_RS19140	COG1126	abc transporter atp-binding protein
ECOK1_RS19180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECOK1_RS19200	COG0551	DNA topoisomerase type I activity
ECOK1_RS19210	COG0758	DNA mediated transformation
ECOK1_RS19230	COG0569	domain protein
ECOK1_RS19240	COG3036	rescue of stalled ribosome
ECOK1_RS19245	COG0789	Transcriptional regulator
ECOK1_RS19285	COG0201	protein transport
ECOK1_RS19375	COG0089	rRNA binding
ECOK1_RS19400	COG3409	Peptidoglycan-binding domain 1 protein
ECOK1_RS19400	COG3267	Type II secretory pathway component ExeA
ECOK1_RS19405	COG3031	protein transport across the cell outer membrane
ECOK1_RS19410	COG1450	Type ii and iii secretion system protein
ECOK1_RS19415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECOK1_RS19420	COG1459	type II secretion system
ECOK1_RS19425	COG2165	general secretion pathway protein
ECOK1_RS19430	COG2165	general secretion pathway protein
ECOK1_RS19435	COG2165	general secretion pathway protein
ECOK1_RS19440	COG4795	General secretion pathway protein
ECOK1_RS19445	COG3156	type II secretion system protein K
ECOK1_RS19450	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECOK1_RS19455	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECOK1_RS19460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ECOK1_RS19465	COG2193	ferroxidase activity
ECOK1_RS19470	COG2906	2 iron, 2 sulfur cluster binding
ECOK1_RS19475	COG3979	chitinase
ECOK1_RS19515	COG2964	Protein conserved in bacteria
ECOK1_RS19520	COG0545	Peptidyl-prolyl cis-trans isomerase
ECOK1_RS19530	COG1047	Peptidyl-prolyl cis-trans
ECOK1_RS19535	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ECOK1_RS19550	COG0488	(ABC) transporter
ECOK1_RS19555	COG0429	hydrolase of the alpha beta-hydrolase fold
ECOK1_RS19565	COG3954	Phosphoribulokinase
ECOK1_RS19570	COG1765	OsmC-like protein
ECOK1_RS19580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECOK1_RS19585	COG1289	transmembrane transporter activity
ECOK1_RS19590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ECOK1_RS19595	COG0512	Glutamine amidotransferase of anthranilate synthase
ECOK1_RS19600	COG2184	nucleotidyltransferase activity
ECOK1_RS19610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECOK1_RS19620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECOK1_RS19625	COG2146	nitrite reductase [NAD(P)H] activity
ECOK1_RS19630	COG2116	formate transmembrane transporter activity
ECOK1_RS19645	COG0626	cystathionine gamma-synthase activity
ECOK1_RS19660	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ECOK1_RS19665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ECOK1_RS19670	COG3457	Alanine racemase
ECOK1_RS19680	COG2188	Transcriptional regulator
ECOK1_RS19685	COG0180	Tryptophanyl-tRNA synthetase
ECOK1_RS19690	COG0546	phosphoglycolate phosphatase activity
ECOK1_RS19695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECOK1_RS19700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ECOK1_RS19705	COG3266	domain, Protein
ECOK1_RS19720	COG4796	Type ii and iii secretion system protein
ECOK1_RS19735	COG3166	PFAM Fimbrial assembly family protein
ECOK1_RS19740	COG4972	Pilus assembly protein
ECOK1_RS19745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ECOK1_RS19750	COG0494	nUDIX hydrolase
ECOK1_RS19760	COG1011	Hydrolase
ECOK1_RS19765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ECOK1_RS19775	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECOK1_RS19800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECOK1_RS19805	COG2183	response to ionizing radiation
ECOK1_RS19810	COG1918	ferrous iron import across plasma membrane
ECOK1_RS19815	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ECOK1_RS19825	COG5464	transposase or invertase
ECOK1_RS19835	COG1040	competence protein
ECOK1_RS19845	COG2610	gluconate transmembrane transporter activity
ECOK1_RS19850	COG1640	4-alpha-glucanotransferase
ECOK1_RS19855	COG0058	SHG alpha-glucan phosphorylase activity
ECOK1_RS19870	COG1690	Belongs to the RtcB family
ECOK1_RS19875	COG4650	regulator
ECOK1_RS19880	COG1349	DNA-binding transcription factor activity
ECOK1_RS19895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECOK1_RS19935	COG3188	usher protein
ECOK1_RS19940	COG3121	Chaperone
ECOK1_RS19950	COG0058	SHG alpha-glucan phosphorylase activity
ECOK1_RS19975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECOK1_RS19980	COG2095	MarC family integral membrane protein
ECOK1_RS19985	COG2610	gluconate transmembrane transporter activity
ECOK1_RS19990	COG3265	gluconokinase activity
ECOK1_RS19995	COG1609	Transcriptional regulator
ECOK1_RS20000	COG1741	Belongs to the pirin family
ECOK1_RS20005	COG0673	inositol 2-dehydrogenase activity
ECOK1_RS20015	COG1247	-acetyltransferase
ECOK1_RS20035	COG0405	Gamma-glutamyltransferase
ECOK1_RS20045	COG0584	glycerophosphoryl diester phosphodiesterase
ECOK1_RS20075	COG0410	ABC transporter
ECOK1_RS20080	COG0411	ABC transporter
ECOK1_RS20085	COG4177	L-phenylalanine transmembrane transporter activity
ECOK1_RS20090	COG0559	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS20095	COG0683	leucine binding
ECOK1_RS20100	COG0456	acetyltransferase
ECOK1_RS20110	COG0683	leucine binding
ECOK1_RS20135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECOK1_RS20140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECOK1_RS20145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECOK1_RS20150	COG2177	Part of the ABC transporter FtsEX involved in
ECOK1_RS20155	COG2884	Cell division ATP-binding protein ftsE
ECOK1_RS20160	COG0552	protein localization to endoplasmic reticulum
ECOK1_RS20165	COG0742	ribosomal rna small subunit methyltransferase
ECOK1_RS20170	COG3776	membrane
ECOK1_RS20180	COG3714	YhhN family
ECOK1_RS20195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ECOK1_RS20205	COG0477	Major facilitator Superfamily
ECOK1_RS20210	COG0628	permease
ECOK1_RS20215	COG2091	lysine biosynthetic process via aminoadipic acid
ECOK1_RS20220	COG0747	negative chemotaxis
ECOK1_RS20225	COG0601	transmembrane transport
ECOK1_RS20230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECOK1_RS20250	COG2188	Transcriptional regulator
ECOK1_RS20260	COG3414	Phosphotransferase system galactitol-specific IIB component
ECOK1_RS20265	COG3775	system Galactitol-specific IIC component
ECOK1_RS20280	COG0191	fructose-bisphosphate aldolase activity
ECOK1_RS20285	COG0842	Transport permease protein
ECOK1_RS20290	COG0842	Transport permease protein
ECOK1_RS20290	COG1129	ABC transporter
ECOK1_RS20295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS20305	COG2081	HI0933 family
ECOK1_RS20310	COG0306	phosphate transporter
ECOK1_RS20320	COG0589	response to stress
ECOK1_RS20325	COG3104	oligopeptide transport
ECOK1_RS20335	COG0339	signal peptide processing
ECOK1_RS20340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ECOK1_RS20345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECOK1_RS20360	COG1393	Belongs to the ArsC family
ECOK1_RS20365	COG3065	identical protein binding
ECOK1_RS20370	COG2197	response regulator
ECOK1_RS20375	COG3720	iron ion transport
ECOK1_RS20380	COG4771	TonB-dependent receptor
ECOK1_RS20400	COG3721	Heme iron utilization protein
ECOK1_RS20410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECOK1_RS20420	COG1285	pathogenesis
ECOK1_RS20435	COG3247	response to pH
ECOK1_RS20440	COG2771	luxR family
ECOK1_RS20450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECOK1_RS20455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECOK1_RS20460	COG2207	Transcriptional regulator
ECOK1_RS20465	COG2207	Transcriptional regulator
ECOK1_RS20470	COG0076	glutamate decarboxylase activity
ECOK1_RS20475	COG1858	cytochrome C peroxidase
ECOK1_RS20485	COG2197	response regulator
ECOK1_RS20490	COG0583	DNA-binding transcription factor activity
ECOK1_RS20495	COG1295	ribonuclease BN
ECOK1_RS20500	COG0477	Major facilitator Superfamily
ECOK1_RS20505	COG2982	Protein involved in outer membrane biogenesis
ECOK1_RS20510	COG2200	EAL domain
ECOK1_RS20520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS20525	COG0612	Peptidase, M16
ECOK1_RS20535	COG2199	diguanylate cyclase activity
ECOK1_RS20535	COG2200	EAL domain
ECOK1_RS20540	COG0457	Tetratricopeptide repeat
ECOK1_RS20540	COG3118	belongs to the thioredoxin family
ECOK1_RS20545	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ECOK1_RS20550	COG1215	transferase activity, transferring glycosyl groups
ECOK1_RS20555	COG1215	transferase activity, transferring glycosyl groups
ECOK1_RS20580	COG2194	sulfuric ester hydrolase activity
ECOK1_RS20605	COG0814	amino acid
ECOK1_RS20610	COG4608	Belongs to the ABC transporter superfamily
ECOK1_RS20615	COG0444	Belongs to the ABC transporter superfamily
ECOK1_RS20620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECOK1_RS20625	COG0601	transmembrane transport
ECOK1_RS20635	COG0747	negative chemotaxis
ECOK1_RS20650	COG2194	sulfuric ester hydrolase activity
ECOK1_RS20655	COG2223	nitrite transmembrane transporter activity
ECOK1_RS20660	COG5571	outer membrane autotransporter
ECOK1_RS20665	COG2818	Glycosylase
ECOK1_RS20670	COG0456	acetyltransferase
ECOK1_RS20675	COG0243	molybdopterin cofactor binding
ECOK1_RS20680	COG2885	chlorophyll binding
ECOK1_RS20695	COG2944	sequence-specific DNA binding
ECOK1_RS20700	COG1278	Cold shock
ECOK1_RS20725	COG3274	enterobacterial common antigen metabolic process
ECOK1_RS20730	COG4682	membrane
ECOK1_RS20735	COG4682	membrane
ECOK1_RS20740	COG1070	Carbohydrate kinase
ECOK1_RS20750	COG4213	ABC transporter substrate-binding protein
ECOK1_RS20760	COG4214	carbohydrate transport
ECOK1_RS20765	COG2207	Transcriptional regulator
ECOK1_RS20765	COG1609	Transcriptional regulator
ECOK1_RS20770	COG2992	FlgJ-related protein
ECOK1_RS20775	COG0366	Alpha amylase catalytic
ECOK1_RS20780	COG3977	Valine--pyruvate aminotransferase
ECOK1_RS20790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECOK1_RS20795	COG1414	Transcriptional regulator
ECOK1_RS20805	COG2731	YhcH YjgK YiaL family protein
ECOK1_RS20815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECOK1_RS20820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECOK1_RS20825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECOK1_RS20830	COG1070	Carbohydrate kinase
ECOK1_RS20835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ECOK1_RS20840	COG3623	hexulose-6-phosphate isomerase
ECOK1_RS20845	COG0235	Class ii aldolase
ECOK1_RS20850	COG1012	belongs to the aldehyde dehydrogenase family
ECOK1_RS20860	COG1454	alcohol dehydrogenase
ECOK1_RS20865	COG3276	selenocysteine insertion sequence binding
ECOK1_RS20875	COG0625	glutathione transferase activity
ECOK1_RS20880	COG1566	PFAM secretion protein HlyD family protein
ECOK1_RS20890	COG2213	PTS system mannitol-specific
ECOK1_RS20890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS20905	COG3722	fumarate hydratase activity
ECOK1_RS20925	COG5295	Hep Hag repeat protein
ECOK1_RS20930	COG1620	l-lactate permease
ECOK1_RS20935	COG2186	Transcriptional regulator
ECOK1_RS20945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ECOK1_RS20950	COG1045	serine acetyltransferase
ECOK1_RS20965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECOK1_RS20970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECOK1_RS20980	COG4942	peptidase
ECOK1_RS20985	COG2861	carbohydrate metabolic process
ECOK1_RS20990	COG1216	Glycosyl transferase, family 2
ECOK1_RS21000	COG0156	8-amino-7-oxononanoate synthase activity
ECOK1_RS21010	COG0859	PFAM glycosyl transferase family 9
ECOK1_RS21015	COG0859	PFAM glycosyl transferase family 9
ECOK1_RS21020	COG3307	-O-antigen
ECOK1_RS21025	COG1216	Glycosyl transferase, family 2
ECOK1_RS21030	COG1442	glycosyl transferase family 8
ECOK1_RS21035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ECOK1_RS21050	COG0515	serine threonine protein kinase
ECOK1_RS21055	COG0438	transferase activity, transferring glycosyl groups
ECOK1_RS21060	COG0859	PFAM glycosyl transferase family 9
ECOK1_RS21065	COG1519	Transferase
ECOK1_RS21095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECOK1_RS21120	COG1561	YicC-like family, N-terminal region
ECOK1_RS21125	COG3645	SOS response
ECOK1_RS21130	COG2860	membrane
ECOK1_RS21140	COG0194	GDP metabolic process
ECOK1_RS21150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECOK1_RS21155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECOK1_RS21160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECOK1_RS21165	COG0786	glutamate:sodium symporter activity
ECOK1_RS21170	COG2233	PERMEase
ECOK1_RS21175	COG2982	Protein involved in outer membrane biogenesis
ECOK1_RS21185	COG1940	carbohydrate kinase activity
ECOK1_RS21200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS21200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS21205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS21210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS21210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS21210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS21215	COG3711	transcriptional antiterminator
ECOK1_RS21220	COG1501	Belongs to the glycosyl hydrolase 31 family
ECOK1_RS21225	COG2211	Major facilitator Superfamily
ECOK1_RS21250	COG0697	spore germination
ECOK1_RS21255	COG1464	Belongs to the NlpA lipoprotein family
ECOK1_RS21280	COG2252	PERMEase
ECOK1_RS21290	COG2271	Major facilitator Superfamily
ECOK1_RS21295	COG2271	Major facilitator Superfamily
ECOK1_RS21300	COG3851	Histidine kinase
ECOK1_RS21305	COG2197	response regulator
ECOK1_RS21310	COG0440	acetolactate synthase activity
ECOK1_RS21315	COG0028	Belongs to the TPP enzyme family
ECOK1_RS21325	COG2814	Major facilitator Superfamily
ECOK1_RS21330	COG0641	radical SAM
ECOK1_RS21340	COG2149	membrane
ECOK1_RS21350	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECOK1_RS21355	COG2207	Transcriptional regulator
ECOK1_RS21380	COG5645	(Lipo)protein
ECOK1_RS21385	COG0823	Involved in the tonB-independent uptake of proteins
ECOK1_RS21395	COG2271	Major facilitator Superfamily
ECOK1_RS21405	COG0800	Aldolase
ECOK1_RS21410	COG3734	2-keto-3-deoxy-galactonokinase
ECOK1_RS21415	COG2186	Transcriptional regulator
ECOK1_RS21425	COG0561	phosphatase activity
ECOK1_RS21430	COG3753	Protein conserved in bacteria
ECOK1_RS21440	COG0187	DNA topoisomerase II activity
ECOK1_RS21450	COG0592	DNA-directed DNA polymerase activity
ECOK1_RS21495	COG0814	amino acid
ECOK1_RS21505	COG0583	DNA-binding transcription factor activity
ECOK1_RS21510	COG2091	lysine biosynthetic process via aminoadipic acid
ECOK1_RS21515	COG0431	NADPH-dependent FMN reductase
ECOK1_RS21520	COG2252	PERMEase
ECOK1_RS21525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECOK1_RS21535	COG0363	glucosamine-6-phosphate deaminase activity
ECOK1_RS21550	COG2723	6-phospho-beta-galactosidase activity
ECOK1_RS21555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS21555	COG1263	PTS System
ECOK1_RS21555	COG2190	(PTS) system
ECOK1_RS21560	COG3711	transcriptional antiterminator
ECOK1_RS21565	COG0704	Plays a role in the regulation of phosphate uptake
ECOK1_RS21570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ECOK1_RS21575	COG0581	inorganic phosphate transmembrane transporter activity
ECOK1_RS21580	COG0573	inorganic phosphate transmembrane transporter activity
ECOK1_RS21585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECOK1_RS21640	COG3312	ion transport
ECOK1_RS21655	COG0716	FMN binding
ECOK1_RS21660	COG1522	sequence-specific DNA binding
ECOK1_RS21695	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS21700	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS21705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS21710	COG1609	Transcriptional regulator
ECOK1_RS21720	COG2186	Transcriptional regulator
ECOK1_RS21760	COG3085	chromosome segregation
ECOK1_RS21765	COG0606	chelatase, subunit chli
ECOK1_RS21780	COG3978	acetolactate synthase activity
ECOK1_RS21785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECOK1_RS21795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECOK1_RS21800	COG0583	DNA-binding transcription factor activity
ECOK1_RS21810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECOK1_RS21815	COG0210	DNA helicase
ECOK1_RS21830	COG3118	belongs to the thioredoxin family
ECOK1_RS21840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECOK1_RS21850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECOK1_RS21855	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECOK1_RS21860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ECOK1_RS21865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ECOK1_RS21870	COG1088	dTDP-glucose 4,6-dehydratase activity
ECOK1_RS21875	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ECOK1_RS21880	COG0456	acetyltransferase
ECOK1_RS21885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ECOK1_RS21890	COG2244	polysaccharide biosynthetic process
ECOK1_RS21910	COG1113	amino acid transport
ECOK1_RS21935	COG0641	radical SAM
ECOK1_RS21940	COG3119	arylsulfatase activity
ECOK1_RS21945	COG3071	HemY protein
ECOK1_RS21950	COG2959	enzyme of heme biosynthesis
ECOK1_RS21955	COG1587	Uroporphyrinogen-III synthase
ECOK1_RS21965	COG3072	Adenylate cyclase
ECOK1_RS21985	COG5567	small periplasmic lipoprotein
ECOK1_RS21995	COG3159	Protein conserved in bacteria
ECOK1_RS22005	COG1011	Hydrolase
ECOK1_RS22010	COG0210	DNA helicase
ECOK1_RS22015	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
ECOK1_RS22020	COG3698	Phosphodiester glycosidase
ECOK1_RS22030	COG0598	Magnesium transport protein CorA
ECOK1_RS22045	COG2962	Rard protein
ECOK1_RS22050	COG2050	protein possibly involved in aromatic compounds catabolism
ECOK1_RS22055	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ECOK1_RS22060	COG0514	ATP-dependent DNA helicase (RecQ)
ECOK1_RS22065	COG1280	lysine exporter protein (LysE YggA)
ECOK1_RS22070	COG1280	lysine exporter protein (LysE YggA)
ECOK1_RS22075	COG2267	carboxylic ester hydrolase activity
ECOK1_RS22080	COG0561	phosphatase activity
ECOK1_RS22085	COG0697	spore germination
ECOK1_RS22090	COG0583	DNA-binding transcription factor activity
ECOK1_RS22110	COG3157	Type VI secretion system effector, Hcp
ECOK1_RS22125	COG2190	(PTS) system
ECOK1_RS22125	COG1263	PTS System
ECOK1_RS22125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS22130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECOK1_RS22135	COG1737	Transcriptional regulator
ECOK1_RS22140	COG0583	DNA-binding transcription factor activity
ECOK1_RS22145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ECOK1_RS22155	COG0549	Belongs to the carbamate kinase family
ECOK1_RS22160	COG1304	FMN binding
ECOK1_RS22165	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECOK1_RS22175	COG1335	isochorismatase
ECOK1_RS22185	COG0412	Dienelactone hydrolase
ECOK1_RS22190	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ECOK1_RS22210	COG0800	Aldolase
ECOK1_RS22215	COG3734	2-keto-3-deoxy-galactonokinase
ECOK1_RS22220	COG1414	Transcriptional regulator
ECOK1_RS22225	COG1322	Protein conserved in bacteria
ECOK1_RS22235	COG3165	ubiquinone biosynthetic process from chorismate
ECOK1_RS22245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECOK1_RS22255	COG0805	protein transport
ECOK1_RS22270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECOK1_RS22275	COG0543	2 iron, 2 sulfur cluster binding
ECOK1_RS22300	COG1739	Uncharacterized protein family UPF0029
ECOK1_RS22305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECOK1_RS22310	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ECOK1_RS22340	COG1763	Mo-molybdopterin cofactor biosynthetic process
ECOK1_RS22345	COG0746	molybdenum cofactor guanylyltransferase activity
ECOK1_RS22350	COG3084	Protein conserved in bacteria
ECOK1_RS22355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ECOK1_RS22360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECOK1_RS22365	COG5339	Protein conserved in bacteria
ECOK1_RS22370	COG0204	Acyl-transferase
ECOK1_RS22380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECOK1_RS22380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECOK1_RS22395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECOK1_RS22405	COG2204	response regulator
ECOK1_RS22410	COG3852	Histidine kinase
ECOK1_RS22415	COG0174	glutamine synthetase
ECOK1_RS22425	COG1217	gtp-binding protein TYPA
ECOK1_RS22430	COG1349	DNA-binding transcription factor activity
ECOK1_RS22435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECOK1_RS22440	COG2084	Dehydrogenase
ECOK1_RS22445	COG3684	Belongs to the aldolase LacD family
ECOK1_RS22450	COG1063	alcohol dehydrogenase
ECOK1_RS22460	COG0477	Major facilitator Superfamily
ECOK1_RS22470	COG1011	Hydrolase
ECOK1_RS22485	COG0456	acetyltransferase
ECOK1_RS22495	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ECOK1_RS22525	COG2864	formate dehydrogenase
ECOK1_RS22530	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS22535	COG0243	molybdopterin cofactor binding
ECOK1_RS22535	COG3383	formate dehydrogenase (NAD+) activity
ECOK1_RS22540	COG3383	formate dehydrogenase (NAD+) activity
ECOK1_RS22540	COG0243	molybdopterin cofactor binding
ECOK1_RS22605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECOK1_RS22620	COG2258	MOSC domain
ECOK1_RS22625	COG2205	protein histidine kinase activity
ECOK1_RS22630	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS22635	COG3678	ATP-independent chaperone mediated protein folding
ECOK1_RS22655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ECOK1_RS22675	COG3152	Membrane
ECOK1_RS22680	COG3691	Protein conserved in bacteria
ECOK1_RS22685	COG0589	response to stress
ECOK1_RS22695	COG1494	fructose-1,6-bisphosphatase
ECOK1_RS22705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ECOK1_RS22720	COG1575	Belongs to the MenA family. Type 1 subfamily
ECOK1_RS22735	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECOK1_RS22740	COG1609	Transcriptional regulator
ECOK1_RS22745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ECOK1_RS22755	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ECOK1_RS22765	COG0626	cystathionine gamma-synthase activity
ECOK1_RS22770	COG0527	aspartate kinase activity
ECOK1_RS22770	COG0460	homoserine dehydrogenase
ECOK1_RS22780	COG0737	Belongs to the 5'-nucleotidase family
ECOK1_RS22795	COG0737	Belongs to the 5'-nucleotidase family
ECOK1_RS22800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ECOK1_RS22810	COG0697	spore germination
ECOK1_RS22815	COG3738	Protein conserved in bacteria
ECOK1_RS22825	COG0371	Dehydrogenase
ECOK1_RS22830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECOK1_RS22835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECOK1_RS22835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS22835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS22840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS22845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS22850	COG1882	Formate acetyltransferase
ECOK1_RS22855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECOK1_RS22860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECOK1_RS22865	COG2207	Transcriptional regulator
ECOK1_RS22870	COG2194	sulfuric ester hydrolase activity
ECOK1_RS22885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ECOK1_RS22900	COG4948	Mandelate Racemase Muconate Lactonizing
ECOK1_RS22905	COG2271	Major facilitator Superfamily
ECOK1_RS22910	COG0583	DNA-binding transcription factor activity
ECOK1_RS22920	COG1473	amidohydrolase
ECOK1_RS22925	COG0477	Major facilitator Superfamily
ECOK1_RS22975	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ECOK1_RS22980	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ECOK1_RS22980	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ECOK1_RS23020	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECOK1_RS23025	COG0250	Participates in transcription elongation, termination and antitermination
ECOK1_RS23060	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ECOK1_RS23070	COG2104	thiamine diphosphate biosynthetic process
ECOK1_RS23075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECOK1_RS23110	COG3068	Protein conserved in bacteria
ECOK1_RS23125	COG3678	ATP-independent chaperone mediated protein folding
ECOK1_RS23130	COG4191	Histidine kinase
ECOK1_RS23135	COG2204	response regulator
ECOK1_RS23140	COG0151	Belongs to the GarS family
ECOK1_RS23175	COG0456	acetyltransferase
ECOK1_RS23185	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECOK1_RS23190	COG2224	Isocitrate lyase
ECOK1_RS23200	COG1414	Transcriptional regulator
ECOK1_RS23205	COG0646	methionine synthase
ECOK1_RS23205	COG1410	methionine synthase
ECOK1_RS23220	COG1283	sodium-dependent phosphate transmembrane transporter activity
ECOK1_RS23270	COG1187	pseudouridine synthase activity
ECOK1_RS23280	COG0527	aspartate kinase activity
ECOK1_RS23305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECOK1_RS23325	COG3833	ABC-type maltose transport systems, permease component
ECOK1_RS23330	COG1175	transmembrane transport
ECOK1_RS23335	COG2182	Extracellular solute-binding protein
ECOK1_RS23345	COG3842	ATPase activity
ECOK1_RS23375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ECOK1_RS23385	COG0534	Mate efflux family protein
ECOK1_RS23390	COG3237	CsbD-like
ECOK1_RS23395	COG0735	belongs to the Fur family
ECOK1_RS23400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECOK1_RS23410	COG0604	alcohol dehydrogenase
ECOK1_RS23415	COG1053	succinate dehydrogenase
ECOK1_RS23420	COG0477	Major facilitator Superfamily
ECOK1_RS23425	COG1024	Enoyl-CoA hydratase
ECOK1_RS23435	COG1609	Transcriptional regulator
ECOK1_RS23440	COG0305	Participates in initiation and elongation during chromosome replication
ECOK1_RS23445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECOK1_RS23450	COG3201	nicotinamide mononucleotide transporter
ECOK1_RS23460	COG1448	Aminotransferase
ECOK1_RS23465	COG0567	Dehydrogenase, E1 component
ECOK1_RS23475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECOK1_RS23480	COG0045	succinate-CoA ligase (ADP-forming) activity
ECOK1_RS23485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECOK1_RS23490	COG0471	metal ion transport
ECOK1_RS23495	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ECOK1_RS23500	COG2204	response regulator
ECOK1_RS23510	COG3700	Belongs to the class B bacterial acid phosphatase family
ECOK1_RS23515	COG0432	Pfam Uncharacterised protein family UPF0047
ECOK1_RS23520	COG2315	Protein conserved in bacteria
ECOK1_RS23525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ECOK1_RS23530	COG0629	single-stranded DNA binding
ECOK1_RS23540	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECOK1_RS23545	COG2207	Transcriptional regulator
ECOK1_RS23550	COG0789	Transcriptional regulator
ECOK1_RS23555	COG2252	PERMEase
ECOK1_RS23560	COG0025	NhaP-type Na H and K H
ECOK1_RS23565	COG0583	DNA-binding transcription factor activity
ECOK1_RS23570	COG1380	Effector of murein hydrolase LrgA
ECOK1_RS23575	COG1346	cytolysis
ECOK1_RS23585	COG3162	membrane
ECOK1_RS23590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECOK1_RS23600	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ECOK1_RS23605	COG0437	4 iron, 4 sulfur cluster binding
ECOK1_RS23610	COG3301	Polysulphide reductase, NrfD
ECOK1_RS23620	COG3088	subunit of a heme lyase
ECOK1_RS23625	COG4235	cytochrome complex assembly
ECOK1_RS23630	COG1301	dicarboxylic acid transport
ECOK1_RS23635	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECOK1_RS23640	COG4608	Belongs to the ABC transporter superfamily
ECOK1_RS23645	COG0444	Belongs to the ABC transporter superfamily
ECOK1_RS23650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECOK1_RS23655	COG0601	transmembrane transport
ECOK1_RS23665	COG3383	formate dehydrogenase (NAD+) activity
ECOK1_RS23670	COG3383	formate dehydrogenase (NAD+) activity
ECOK1_RS23680	COG1289	transmembrane transporter activity
ECOK1_RS23685	COG1566	PFAM secretion protein HlyD family protein
ECOK1_RS23695	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ECOK1_RS23700	COG1940	carbohydrate kinase activity
ECOK1_RS23705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECOK1_RS23710	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS23715	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS23720	COG1129	ABC transporter
ECOK1_RS23725	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS23730	COG1737	Transcriptional regulator
ECOK1_RS23735	COG0698	ribose 5-phosphate isomerase
ECOK1_RS23745	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ECOK1_RS23750	COG0456	acetyltransferase
ECOK1_RS23760	COG3454	Phosphonate metabolism
ECOK1_RS23765	COG4778	phosphonate C-P lyase system protein PhnL
ECOK1_RS23770	COG4107	phosphonate C-P lyase system protein PhnK
ECOK1_RS23775	COG3627	carbon phosphorus lyase activity
ECOK1_RS23780	COG3626	phosphonate metabolism
ECOK1_RS23785	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ECOK1_RS23790	COG3624	Phosphonate C-P lyase system protein PhnG
ECOK1_RS23795	COG2188	Transcriptional regulator
ECOK1_RS23800	COG3639	organic phosphonate transmembrane transporter activity
ECOK1_RS23805	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ECOK1_RS23815	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ECOK1_RS23820	COG2824	Alkylphosphonate utilization operon protein PhnA
ECOK1_RS23835	COG0477	Major facilitator Superfamily
ECOK1_RS23845	COG0642	Histidine kinase
ECOK1_RS23850	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS23855	COG2194	sulfuric ester hydrolase activity
ECOK1_RS23860	COG0531	amino acid
ECOK1_RS23865	COG2207	Transcriptional regulator
ECOK1_RS23875	COG2169	Transcriptional regulator
ECOK1_RS23885	COG1486	melibiose metabolic process
ECOK1_RS23890	COG3647	Membrane
ECOK1_RS23895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECOK1_RS23895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECOK1_RS23900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECOK1_RS23910	COG4565	transcriptional regulatory protein
ECOK1_RS23915	COG3290	protein histidine kinase activity
ECOK1_RS23920	COG3592	Divergent 4Fe-4S mono-cluster
ECOK1_RS23925	COG2388	GCN5-related N-acetyl-transferase
ECOK1_RS23940	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECOK1_RS23945	COG3104	oligopeptide transport
ECOK1_RS23950	COG1982	Orn Lys Arg decarboxylase major
ECOK1_RS23955	COG0531	amino acid
ECOK1_RS23960	COG3710	Transcriptional regulator
ECOK1_RS23975	COG1309	transcriptional regulator
ECOK1_RS23990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECOK1_RS23995	COG1027	Aspartate ammonia-lyase
ECOK1_RS24000	COG3030	protein affecting phage T7 exclusion by the F plasmid
ECOK1_RS24005	COG0531	amino acid
ECOK1_RS24030	COG1509	lysine 2,3-aminomutase activity
ECOK1_RS24040	COG5510	response to toxic substance
ECOK1_RS24045	COG5510	response to toxic substance
ECOK1_RS24050	COG2076	Multidrug Resistance protein
ECOK1_RS24055	COG3040	lipid binding
ECOK1_RS24060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECOK1_RS24075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECOK1_RS24080	COG1053	succinate dehydrogenase
ECOK1_RS24090	COG0531	amino acid
ECOK1_RS24105	COG3264	Mechanosensitive ion channel
ECOK1_RS24105	COG1511	domain protein
ECOK1_RS24145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECOK1_RS24145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ECOK1_RS24150	COG0802	atpase or kinase
ECOK1_RS24155	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECOK1_RS24175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ECOK1_RS24180	COG0330	HflC and HflK could
ECOK1_RS24185	COG0330	HflC and HflK could
ECOK1_RS24190	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ECOK1_RS24205	COG0557	exoribonuclease II activity
ECOK1_RS24210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECOK1_RS24215	COG3789	protein conserved in bacteria
ECOK1_RS24220	COG1842	Phage shock protein A
ECOK1_RS24230	COG3766	membrane
ECOK1_RS24235	COG5463	Belongs to the UPF0441 family
ECOK1_RS24240	COG0754	glutathionylspermidine amidase activity
ECOK1_RS24245	COG1960	acyl-CoA dehydrogenase activity
ECOK1_RS24255	COG3650	response to hydrogen peroxide
ECOK1_RS24260	COG1073	alpha beta
ECOK1_RS24275	COG3037	sugar-specific permease SgaT UlaA
ECOK1_RS24280	COG3414	Phosphotransferase system galactitol-specific IIB component
ECOK1_RS24325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ECOK1_RS24345	COG2271	Major facilitator Superfamily
ECOK1_RS24350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECOK1_RS24355	COG4670	ketone body catabolic process
ECOK1_RS24360	COG1024	Enoyl-CoA hydratase
ECOK1_RS24375	COG1309	transcriptional regulator
ECOK1_RS24380	COG3061	Opacity-associated protein A
ECOK1_RS24385	COG0545	Peptidyl-prolyl cis-trans isomerase
ECOK1_RS24390	COG1113	amino acid transport
ECOK1_RS24400	COG0697	spore germination
ECOK1_RS24405	COG0702	epimerase
ECOK1_RS24410	COG1733	regulation of RNA biosynthetic process
ECOK1_RS24415	COG0737	Belongs to the 5'-nucleotidase family
ECOK1_RS24420	COG1218	3'(2'),5'-bisphosphate nucleotidase
ECOK1_RS24425	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECOK1_RS24435	COG1253	flavin adenine dinucleotide binding
ECOK1_RS24450	COG0729	surface antigen
ECOK1_RS24455	COG2911	Protein conserved in bacteria
ECOK1_RS24460	COG2105	PFAM AIG2 family protein
ECOK1_RS24465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ECOK1_RS24470	COG1879	ABC-type sugar transport system periplasmic component
ECOK1_RS24475	COG1129	ABC transporter
ECOK1_RS24480	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS24485	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECOK1_RS24495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECOK1_RS24505	COG0312	modulator of DNA gyrase
ECOK1_RS24510	COG3783	Cytochrome b(562)
ECOK1_RS24515	COG0602	queuosine metabolic process
ECOK1_RS24520	COG1328	CTP reductase activity
ECOK1_RS24530	COG0366	Alpha amylase catalytic
ECOK1_RS24535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECOK1_RS24535	COG1263	PTS System
ECOK1_RS24540	COG1609	Transcriptional regulator
ECOK1_RS24545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ECOK1_RS24550	COG0251	oxidation-reduction process
ECOK1_RS24570	COG1438	arginine binding
ECOK1_RS24575	COG1288	antiporter activity
ECOK1_RS24580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECOK1_RS24585	COG0549	Belongs to the carbamate kinase family
ECOK1_RS24595	COG2731	YhcH YjgK YiaL family protein
ECOK1_RS24600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECOK1_RS24605	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ECOK1_RS24610	COG0456	acetyltransferase
ECOK1_RS24620	COG0525	valine-tRNA ligase activity
ECOK1_RS24625	COG2927	DNA polymerase III (CHI subunit)
ECOK1_RS24635	COG0795	lipopolysaccharide-transporting ATPase activity
ECOK1_RS24640	COG0795	lipopolysaccharide-transporting ATPase activity
ECOK1_RS24645	COG0433	COG0433 Predicted ATPase
ECOK1_RS24650	COG1609	Transcriptional regulator
ECOK1_RS24655	COG2610	gluconate transmembrane transporter activity
ECOK1_RS24660	COG1028	Short-chain dehydrogenase reductase Sdr
ECOK1_RS24665	COG1063	alcohol dehydrogenase
ECOK1_RS24670	COG3265	gluconokinase activity
ECOK1_RS24675	COG1064	alcohol dehydrogenase
ECOK1_RS24685	COG0582	viral genome integration into host DNA
ECOK1_RS24780	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECOK1_RS24795	COG0582	viral genome integration into host DNA
ECOK1_RS24800	COG4974	Belongs to the 'phage' integrase family
ECOK1_RS24815	COG3539	Fimbrial protein
ECOK1_RS24820	COG3121	Chaperone
ECOK1_RS24825	COG3188	usher protein
ECOK1_RS24830	COG3539	Fimbrial protein
ECOK1_RS24835	COG3539	Fimbrial protein
ECOK1_RS24840	COG3539	Fimbrial protein
ECOK1_RS24855	COG0246	Mannitol dehydrogenase
ECOK1_RS24865	COG2186	Transcriptional regulator
ECOK1_RS24880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECOK1_RS24880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECOK1_RS24885	COG1461	Dihydroxyacetone kinase
ECOK1_RS24890	COG2376	Dihydroxyacetone kinase
ECOK1_RS24905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECOK1_RS24920	COG1929	Belongs to the glycerate kinase type-1 family
ECOK1_RS24925	COG2084	Dehydrogenase
ECOK1_RS24940	COG3284	Transcriptional regulator
ECOK1_RS24950	COG1757	Na H antiporter
ECOK1_RS24955	COG0583	DNA-binding transcription factor activity
ECOK1_RS24960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECOK1_RS24965	COG0700	Nucleoside recognition
ECOK1_RS24970	COG3366	ferrous iron transmembrane transporter activity
ECOK1_RS24985	COG0477	Major facilitator Superfamily
ECOK1_RS25000	COG1924	4 iron, 4 sulfur cluster binding
ECOK1_RS25005	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ECOK1_RS25010	COG2733	membrane
ECOK1_RS25030	COG0732	type I restriction modification DNA specificity domain
ECOK1_RS25035	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ECOK1_RS25040	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ECOK1_RS25045	COG1715	Restriction endonuclease
ECOK1_RS25050	COG0523	cobalamin synthesis protein
ECOK1_RS25055	COG2879	small protein
ECOK1_RS25060	COG1966	Carbon starvation protein
ECOK1_RS25070	COG0840	transmembrane signaling receptor activity
ECOK1_RS25075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECOK1_RS25085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECOK1_RS25090	COG0025	NhaP-type Na H and K H
ECOK1_RS25095	COG1802	Transcriptional regulator
ECOK1_RS25100	COG1063	alcohol dehydrogenase
ECOK1_RS25115	COG1484	DNA-dependent DNA replication
ECOK1_RS25130	COG2966	Psort location CytoplasmicMembrane, score
ECOK1_RS25135	COG2197	response regulator
ECOK1_RS25140	COG2197	response regulator
ECOK1_RS25145	COG4114	ferric iron reductase
ECOK1_RS25180	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ECOK1_RS25185	COG0456	acetyltransferase
ECOK1_RS25190	COG1011	Hydrolase
ECOK1_RS25215	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ECOK1_RS25220	COG5532	Uncharacterized conserved protein (DUF2303)
ECOK1_RS25230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECOK1_RS25235	COG4197	protein conserved in bacteria, prophage-related
ECOK1_RS25255	COG1846	Transcriptional regulator
ECOK1_RS25265	COG4725	Belongs to the MT-A70-like family
ECOK1_RS25275	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECOK1_RS25285	COG1403	HNH endonuclease
ECOK1_RS25290	COG0484	heat shock protein binding
ECOK1_RS25320	COG3772	lysozyme
ECOK1_RS25365	COG0740	serine-type endopeptidase activity
ECOK1_RS25440	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECOK1_RS25480	COG2823	Periplasmic or secreted lipoprotein
ECOK1_RS25490	COG4667	esterase of the alpha-beta hydrolase superfamily
ECOK1_RS25495	COG0084	hydrolase, TatD family'
ECOK1_RS25500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECOK1_RS25505	COG1328	CTP reductase activity
ECOK1_RS25535	COG3550	peptidyl-serine autophosphorylation
ECOK1_RS25545	COG3726	membrane protein affecting hemolysin expression
ECOK1_RS25550	COG0560	Phosphoserine phosphatase
ECOK1_RS25555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECOK1_RS25560	COG3172	ATPase kinase involved in NAD metabolism
ECOK1_RS25560	COG1056	cytidyltransferase-related domain
ECOK1_RS25565	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ECOK1_RS25575	COG0488	(ABC) transporter
ECOK1_RS25580	COG0741	lytic transglycosylase activity
ECOK1_RS25600	COG2207	Transcriptional regulator
ECOK1_RS25600	COG3708	Transcriptional regulator
ECOK1_RS25605	COG3045	CreA protein
ECOK1_RS25610	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS25615	COG2205	protein histidine kinase activity
ECOK1_RS25620	COG4452	Inner membrane protein CreD
ECOK1_RS25625	COG0745	RESPONSE REGULATOR receiver
ECOK1_RS25635	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ECOK1_RS25685	COG2963	transposase activity